46 CFR 175.900 - OMB control numbers.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 7 2014-10-01 2014-10-01 false OMB control numbers. 175.900 Section 175.900 Shipping...) GENERAL PROVISIONS § 175.900 OMB control numbers. (a) Purpose. This section lists the control numbers... that agencies display a current control number assigned by the Director of OMB for each approved agency...

46 CFR 169.117 - OMB control numbers.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 7 2012-10-01 2012-10-01 false OMB control numbers. 169.117 Section 169.117 Shipping... Provisions § 169.117 OMB control numbers. (a) Purpose. This section collects and displays the control numbers... that agencies display a current control number assigned by the Director of OMB for each approved agency...

46 CFR 175.900 - OMB control numbers.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 7 2012-10-01 2012-10-01 false OMB control numbers. 175.900 Section 175.900 Shipping...) GENERAL PROVISIONS § 175.900 OMB control numbers. (a) Purpose. This section lists the control numbers... that agencies display a current control number assigned by the Director of OMB for each approved agency...

7 CFR 63.505 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false OMB control number. 63.505 Section 63.505 Agriculture... IMPROVEMENT CENTER General Provisions Miscellaneous § 63.505 OMB control number. The control number assigned... pursuant to the Paperwork Reduction Act of 1995, 44 U.S.C. Chapter 35, is OMB control number 0505-new. ...

27 CFR 53.187 - OMB control numbers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2012-04-01 2011-04-01 true OMB control numbers. 53.187... numbers. (a) Purpose. This section collects and displays the control numbers assigned to collections of... control numbers assigned by OMB to collections of information in the regulations in this part. (b) Display...

Development and Validation of the Eating Loss of Control Scale

PubMed Central

Blomquist, Kerstin K.; Roberto, Christina A.; Barnes, Rachel D.; White, Marney A.; Masheb, Robin M.; Grilo, Carlos M.

2014-01-01

Recurrent objective bulimic episodes (OBE) are a defining diagnostic characteristic of binge eating disorder (BED) and bulimia nervosa (BN). OBEs are characterized by experiencing loss of control (LOC) while eating an unusually large quantity of food. Despite nosological importance and complex heterogeneity across patients, measurement of LOC has been assessed dichotomously (present/absent). This study describes the development and initial validation of the Eating Loss of Control Scale (ELOCS), a self-report questionnaire that examines the complexity of the LOC construct. Participants were 168 obese treatment-seeking individuals with BED who completed the Eating Disorder Examination interview and self-report measures. Participants rated their LOC-related feelings or behaviors on continuous Likert-type scales and reported the number of LOC episodes in the past 28 days. Principal component analysis identified a single-factor, 18-item scale, which demonstrated good internal reliability (α=0.90). Frequency of LOC episodes was significantly correlated with frequency of OBEs and subjective bulimic episodes. The ELOCS demonstrated good convergent validity and was significantly correlated with greater eating pathology, greater emotion dysregulation, greater depression, and lower self-control, but not with BMI. The findings suggest that the ELOCS is a valid self-report questionnaire that may provide important clinical information regarding experiences of LOC in obese persons with BED. Future research should examine the ELOCS in other eating disorders and non-clinical samples. PMID:24219700

7 CFR 785.13 - OMB Control Number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 7 2012-01-01 2012-01-01 false OMB Control Number. 785.13 Section 785.13 Agriculture... SPECIAL PROGRAMS CERTIFIED STATE MEDIATION PROGRAM § 785.13 OMB Control Number. The information collection... control number 0560-0165. ...

7 CFR 1782.100 - OMB Control Number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true OMB Control Number. 1782.100 Section 1782.100... AGRICULTURE (CONTINUED) SERVICING OF WATER AND WASTE PROGRAMS § 1782.100 OMB Control Number. The information... OMB Control Number 0572-0137. ...

7 CFR 1782.100 - OMB Control Number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 12 2011-01-01 2011-01-01 false OMB Control Number. 1782.100 Section 1782.100... AGRICULTURE (CONTINUED) SERVICING OF WATER AND WASTE PROGRAMS § 1782.100 OMB Control Number. The information... OMB Control Number 0572-0137. ...

7 CFR 1782.100 - OMB Control Number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false OMB Control Number. 1782.100 Section 1782.100... AGRICULTURE (CONTINUED) SERVICING OF WATER AND WASTE PROGRAMS § 1782.100 OMB Control Number. The information... OMB Control Number 0572-0137. ...

7 CFR 1775.9 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true OMB control number. 1775.9 Section 1775.9 Agriculture... (CONTINUED) TECHNICAL ASSISTANCE GRANTS General Provisions § 1775.9 OMB control number. The information... have been assigned OMB control number 0572-0112. ...

7 CFR 407.4 - OMB control numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 6 2010-01-01 2010-01-01 false OMB control numbers. 407.4 Section 407.4 Agriculture... AGRICULTURE GROUP RISK PLAN OF INSURANCE REGULATIONS § 407.4 OMB control numbers. The information collection...) under control number 0563-0053. ...

7 CFR 1775.9 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 12 2011-01-01 2011-01-01 false OMB control number. 1775.9 Section 1775.9 Agriculture... (CONTINUED) TECHNICAL ASSISTANCE GRANTS General Provisions § 1775.9 OMB control number. The information... have been assigned OMB control number 0572-0112. ...

7 CFR 1775.9 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false OMB control number. 1775.9 Section 1775.9 Agriculture... (CONTINUED) TECHNICAL ASSISTANCE GRANTS General Provisions § 1775.9 OMB control number. The information... have been assigned OMB control number 0572-0112. ...

7 CFR 407.4 - OMB control numbers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE GROUP RISK PLAN OF INSURANCE REGULATIONS § 407.4 OMB control numbers. The information collection... 7 Agriculture 6 2011-01-01 2011-01-01 false OMB control numbers. 407.4 Section 407.4 Agriculture...) under control number 0563-0053. ...

31 CFR 25.101 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false OMB control number. 25.101 Section 25... control number. The reporting requirements in this part have been approved under the Office of Management and Budget control number 1505-0109. ...

7 CFR 1778.100 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 12 2011-01-01 2011-01-01 false OMB control number. 1778.100 Section 1778.100... AGRICULTURE (CONTINUED) EMERGENCY AND IMMINENT COMMUNITY WATER ASSISTANCE GRANTS § 1778.100 OMB control number... Management and Budget and assigned OMB control number 0572-0110. ...

7 CFR 1778.100 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true OMB control number. 1778.100 Section 1778.100... AGRICULTURE (CONTINUED) EMERGENCY AND IMMINENT COMMUNITY WATER ASSISTANCE GRANTS § 1778.100 OMB control number... Management and Budget and assigned OMB control number 0572-0110. ...

7 CFR 1778.100 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false OMB control number. 1778.100 Section 1778.100... AGRICULTURE (CONTINUED) EMERGENCY AND IMMINENT COMMUNITY WATER ASSISTANCE GRANTS § 1778.100 OMB control number... Management and Budget and assigned OMB control number 0572-0110. ...

7 CFR 1779.100 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false OMB control number. 1779.100 Section 1779.100... AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.100 OMB control number. The... Management and Budget and have been assigned OMB control number 0572-0122. ...

7 CFR 1774.100 - OMB Control Number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 12 2011-01-01 2011-01-01 false OMB Control Number. 1774.100 Section 1774.100...) Grant Application Processing § 1774.100 OMB Control Number. The information collection requirements in... the submission of a paperwork package to OMB and assigned an OMB Control Number. ...

7 CFR 1774.100 - OMB Control Number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false OMB Control Number. 1774.100 Section 1774.100...) Grant Application Processing § 1774.100 OMB Control Number. The information collection requirements in... the submission of a paperwork package to OMB and assigned an OMB Control Number. ...

7 CFR 1779.100 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 12 2011-01-01 2011-01-01 false OMB control number. 1779.100 Section 1779.100... AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.100 OMB control number. The... Management and Budget and have been assigned OMB control number 0572-0122. ...

7 CFR 1774.100 - OMB Control Number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true OMB Control Number. 1774.100 Section 1774.100...) Grant Application Processing § 1774.100 OMB Control Number. The information collection requirements in... the submission of a paperwork package to OMB and assigned an OMB Control Number. ...

7 CFR 1779.100 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true OMB control number. 1779.100 Section 1779.100... AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.100 OMB control number. The... Management and Budget and have been assigned OMB control number 0572-0122. ...

12 CFR 1805.106 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 9 2013-01-01 2013-01-01 false OMB control number. 1805.106 Section 1805.106... COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS PROGRAM General Provisions § 1805.106 OMB control number. The... and assigned OMB control numbers 1559-0006, 1559-0021 and 1559-0022. ...

46 CFR 169.117 - OMB control numbers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false OMB control numbers. 169.117 Section 169.117 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS General Provisions § 169.117 OMB control numbers. (a) Purpose. This section collects and displays the control numbers...

46 CFR 169.117 - OMB control numbers.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false OMB control numbers. 169.117 Section 169.117 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS General Provisions § 169.117 OMB control numbers. (a) Purpose. This section collects and displays the control numbers...

7 CFR 1940.1000 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 13 2014-01-01 2013-01-01 true OMB control number. 1940.1000 Section 1940.1000....1000 OMB control number. The collection of information requirements contained in this regulation has been approved by the Office of Management and Budget and assigned OMB control number 0575-0145. Public...

48 CFR 901.105 - OMB control numbers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false OMB control numbers. 901... ACQUISITION REGULATIONS SYSTEM Purpose, Authority, Issuance 901.105 OMB control numbers. The Paperwork... members of the public be cleared by that Office. The OMB control number for the collection of information...

7 CFR 1924.50 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true OMB control number. 1924.50 Section 1924.50... control number. The reporting and recordkeeping requirements contained in this regulation have been approved by the Office of Management and Budget (OMB) and have been assigned OMB control number 0575-0042...

7 CFR 205.690 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false OMB control number. 205.690 Section 205.690... PROVISIONS NATIONAL ORGANIC PROGRAM Administrative Miscellaneous § 205.690 OMB control number. The control number assigned to the information collection requirements in this part by the Office of Management and...

7 CFR 1940.1000 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 13 2013-01-01 2013-01-01 false OMB control number. 1940.1000 Section 1940.1000....1000 OMB control number. The collection of information requirements contained in this regulation has been approved by the Office of Management and Budget and assigned OMB control number 0575-0145. Public...

7 CFR 1927.100 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false OMB control number. 1927.100 Section 1927.100... control number. The reporting requirements contained in this regulation have been approved by the Office of Management and Budget and have been assigned OMB control number 0575-0147. Public reporting burden...

7 CFR 1944.100 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 13 2014-01-01 2013-01-01 true OMB control number. 1944.100 Section 1944.100...) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing Application Packaging Grants § 1944.100 OMB control number... Office of Management and Budget and have been assigned OMB control number 0575-0157. Public reporting...

7 CFR 1924.50 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 12 2011-01-01 2011-01-01 false OMB control number. 1924.50 Section 1924.50... control number. The reporting and recordkeeping requirements contained in this regulation have been approved by the Office of Management and Budget (OMB) and have been assigned OMB control number 0575-0042...

7 CFR 1924.50 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false OMB control number. 1924.50 Section 1924.50... control number. The reporting and recordkeeping requirements contained in this regulation have been approved by the Office of Management and Budget (OMB) and have been assigned OMB control number 0575-0042...

7 CFR 1924.300 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false OMB control number. 1924.300 Section 1924.300... control number. The reporting and recordkeeping requirements contained in this regulation have been approved by the Office of Management and Budget (OMB) and have been assigned OMB control number 0575-0082...

5 CFR 2634.414 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false OMB control number. 2634.414 Section 2634... DISCLOSURE, QUALIFIED TRUSTS, AND CERTIFICATES OF DIVESTITURE Qualified Trusts § 2634.414 OMB control number... the Certificates), are all approved by the Office of Management and Budget under control number 3209...

7 CFR 1944.100 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 13 2013-01-01 2013-01-01 false OMB control number. 1944.100 Section 1944.100...) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing Application Packaging Grants § 1944.100 OMB control number... Office of Management and Budget and have been assigned OMB control number 0575-0157. Public reporting...

7 CFR 1924.300 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true OMB control number. 1924.300 Section 1924.300... control number. The reporting and recordkeeping requirements contained in this regulation have been approved by the Office of Management and Budget (OMB) and have been assigned OMB control number 0575-0082...

7 CFR 1942.50 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 13 2013-01-01 2013-01-01 false OMB control number. 1942.50 Section 1942.50...) PROGRAM REGULATIONS (CONTINUED) ASSOCIATIONS Community Facility Loans § 1942.50 OMB control number. The... Management and Budget (OMB) and have been assigned OMB control number 0575-0015. Public reporting burden for...

7 CFR 1927.100 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true OMB control number. 1927.100 Section 1927.100... control number. The reporting requirements contained in this regulation have been approved by the Office of Management and Budget and have been assigned OMB control number 0575-0147. Public reporting burden...

7 CFR 1942.50 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 13 2014-01-01 2013-01-01 true OMB control number. 1942.50 Section 1942.50...) PROGRAM REGULATIONS (CONTINUED) ASSOCIATIONS Community Facility Loans § 1942.50 OMB control number. The... Management and Budget (OMB) and have been assigned OMB control number 0575-0015. Public reporting burden for...

7 CFR 1927.100 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 12 2011-01-01 2011-01-01 false OMB control number. 1927.100 Section 1927.100... control number. The reporting requirements contained in this regulation have been approved by the Office of Management and Budget and have been assigned OMB control number 0575-0147. Public reporting burden...

Sweep and Compressibility Effects on Active Separation Control at High Reynolds Numbers

NASA Technical Reports Server (NTRS)

Seifert, Avi; Pack, LaTunia G.

2000-01-01

This paper explores the effects of compressibility, sweep and excitation location on active separation control at high Reynolds numbers. The model, which was tested in a cryogenic pressurized wind tunnel, simulates the upper surface of a 20% thick GlauertGoldschmied type airfoil at zero angle of attack. The flow is fully turbulent since the tunnel sidewall boundary layer flows over the model. Without control, the flow separates at the highly convex area and a large turbulent separation bubble is formed. Periodic excitation is applied to gradually eliminate the separation bubble. Two alternative blowing slot locations as well as the effect of compressibility, sweep and steady suction or blowing were studied. During the test the Reynolds numbers ranged from 2 to 40 million and Mach numbers ranged from 0.2 to 0.7. Sweep angles were 0 and 30 deg. It was found that excitation must be introduced slightly upstream of the separation region regardless of the sweep angle at low Mach number. Introduction of excitation upstream of the shock wave is more effective than at its foot. Compressibility reduces the ability of steady mass transfer and periodic excitation to control the separation bubble but excitation has an effect on the integral parameters, which is similar to that observed in low Mach numbers. The conventional swept flow scaling is valid for fully and even partially attached flow, but different scaling is required for the separated 3D flow. The effectiveness of the active control is not reduced by sweep. Detailed flow field dynamics are described in the accompanying paper.

Sweep and Compressibility Effects on Active Separation Control at High Reynolds Numbers

NASA Technical Reports Server (NTRS)

Seifert, Avi; Pack, LaTunia G.

2000-01-01

This paper explores the effects of compressibility, sweep and excitation location on active separation control at high Reynolds numbers. The model, which was tested in a cryogenic pressurized wind tunnel, simulates the upper surface of a 20% thick Glauert Goldschmied type airfoil at zero angle of attack. The flow is fully turbulent since the tunnel sidewall boundary layer flows over the model. Without control, the flow separates at the highly convex area and a large turbulent separation bubble is formed. Periodic excitation is applied to gradually eliminate the separation bubble. Two alternative blowing slot locations as well as the effect of compressibility, sweep and steady suction or blowing were studied. During the test the Reynolds numbers ranged from 2 to 40 million and Mach numbers ranged from 0.2 to 0.7. Sweep angles were 0 and 30 deg. It was found that excitation must be introduced slightly upstream of the separation region regardless of the sweep angle at low Mach number. Introduction of excitation upstream of the shock wave is more effective than at its foot. Compressibility reduces the ability of steady mass transfer and periodic excitation to control the separation bubble but excitation has an effect on the integral parameters, which is similar to that observed in low Mach numbers. The conventional swept flow scaling is valid for fully and even partially attached flow, but different scaling is required for the separated 3D flow. The effectiveness of the active control is not reduced by sweep. Detailed flow field dynamics are described in the accompanying paper.

7 CFR 1777.100 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 12 2011-01-01 2011-01-01 false OMB control number. 1777.100 Section 1777.100... AGRICULTURE (CONTINUED) SECTION 306C WWD LOANS AND GRANTS § 1777.100 OMB control number. The reporting and... assigned OMB control number 0570-0001. Public reporting burden for this collection of information is...

7 CFR 1902.50 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false OMB control number. 1902.50 Section 1902.50... control number. The reporting and recordkeeping requirements contained in this regulation have been approved by the OMB and have been assigned OMB Control Number 0575-0158. [70 FR 59228, Oct. 12, 2005] ...

7 CFR 56.9 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false OMB control number. 56.9 Section 56.9 Agriculture... EGGS Grading of Shell Eggs General § 56.9 OMB control number. (a) Purpose. The collecting of... assigned OMB control number 0581-0128. (b) Display. Sections Where Information Collection Requirements Are...

7 CFR 1902.50 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true OMB control number. 1902.50 Section 1902.50... control number. The reporting and recordkeeping requirements contained in this regulation have been approved by the OMB and have been assigned OMB Control Number 0575-0158. [70 FR 59228, Oct. 12, 2005] ...

7 CFR 1942.150 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 13 2014-01-01 2013-01-01 true OMB control number. 1942.150 Section 1942.150... § 1942.150 OMB control number. The collection of information requirements in this regulation have been approved by the Office of Management and Budget and have been assigned OMB control number 0575-0120. ...

7 CFR 1942.150 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 13 2013-01-01 2013-01-01 false OMB control number. 1942.150 Section 1942.150... § 1942.150 OMB control number. The collection of information requirements in this regulation have been approved by the Office of Management and Budget and have been assigned OMB control number 0575-0120. ...

7 CFR 1777.100 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false OMB control number. 1777.100 Section 1777.100... AGRICULTURE (CONTINUED) SECTION 306C WWD LOANS AND GRANTS § 1777.100 OMB control number. The reporting and... assigned OMB control number 0570-0001. Public reporting burden for this collection of information is...

7 CFR 1777.100 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true OMB control number. 1777.100 Section 1777.100... AGRICULTURE (CONTINUED) SECTION 306C WWD LOANS AND GRANTS § 1777.100 OMB control number. The reporting and... assigned OMB control number 0570-0001. Public reporting burden for this collection of information is...

7 CFR 1902.50 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 12 2011-01-01 2011-01-01 false OMB control number. 1902.50 Section 1902.50... control number. The reporting and recordkeeping requirements contained in this regulation have been approved by the OMB and have been assigned OMB Control Number 0575-0158. [70 FR 59228, Oct. 12, 2005] ...

12 CFR 1815.115 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 9 2013-01-01 2013-01-01 false OMB control number. 1815.115 Section 1815.115... ENVIRONMENTAL QUALITY § 1815.115 OMB control number. The collection of information requirements in this part have been approved by the Office of Management and Budget and assigned OMB control number 1505-0153...

29 CFR 4010.15 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 9 2011-07-01 2011-07-01 false OMB control number. 4010.15 Section 4010.15 Labor... DISCLOSURE REQUIREMENTS ANNUAL FINANCIAL AND ACTUARIAL INFORMATION REPORTING § 4010.15 OMB control number... Management and Budget under OMB control number 1212-0049. [61 FR 34022, July 1, 1996. Redesignated at 74 FR...

7 CFR 57.18 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false OMB control number. 57.18 Section 57.18 Agriculture... PRODUCTS INSPECTION ACT) Regulations Governing the Inspection of Eggs General § 57.18 OMB control number... and Budget and assigned OMB control number 0581-0113. [63 FR 69970, Dec. 17, 1998] Scope of Inspection ...

12 CFR 363.0 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false OMB control number. 363.0 Section 363.0 Banks... INDEPENDENT AUDITS AND REPORTING REQUIREMENTS § 363.0 OMB control number. The information collection requirements in this part have been approved by the Office of Management and Budget under OMB control number...

29 CFR 4010.15 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 9 2013-07-01 2013-07-01 false OMB control number. 4010.15 Section 4010.15 Labor... DISCLOSURE REQUIREMENTS ANNUAL FINANCIAL AND ACTUARIAL INFORMATION REPORTING § 4010.15 OMB control number... Management and Budget under OMB control number 1212-0049. [61 FR 34022, July 1, 1996. Redesignated at 74 FR...

29 CFR 4010.15 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false OMB control number. 4010.15 Section 4010.15 Labor... DISCLOSURE REQUIREMENTS ANNUAL FINANCIAL AND ACTUARIAL INFORMATION REPORTING § 4010.15 OMB control number... Management and Budget under OMB control number 1212-0049. [61 FR 34022, July 1, 1996. Redesignated at 74 FR...

12 CFR 363.0 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 5 2013-01-01 2013-01-01 false OMB control number. 363.0 Section 363.0 Banks... INDEPENDENT AUDITS AND REPORTING REQUIREMENTS § 363.0 OMB control number. The information collection requirements in this part have been approved by the Office of Management and Budget under OMB control number...

29 CFR 4010.15 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 9 2012-07-01 2012-07-01 false OMB control number. 4010.15 Section 4010.15 Labor... DISCLOSURE REQUIREMENTS ANNUAL FINANCIAL AND ACTUARIAL INFORMATION REPORTING § 4010.15 OMB control number... Management and Budget under OMB control number 1212-0049. [61 FR 34022, July 1, 1996. Redesignated at 74 FR...

46 CFR 28.20 - OMB control numbers.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false OMB control numbers. 28.20 Section 28.20 Shipping COAST... VESSELS General Provisions § 28.20 OMB control numbers. (a) This section collects and displays the control numbers assigned to information collection and recordkeeping requirements in this part by the Office of...

46 CFR 28.20 - OMB control numbers.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false OMB control numbers. 28.20 Section 28.20 Shipping COAST... VESSELS General Provisions § 28.20 OMB control numbers. (a) This section collects and displays the control numbers assigned to information collection and recordkeeping requirements in this part by the Office of...

29 CFR 4011.11 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false OMB control number. 4011.11 Section 4011.11 Labor... DISCLOSURE REQUIREMENTS DISCLOSURE TO PARTICIPANTS § 4011.11 OMB control number. The collections of... number 1212-0050. ...

29 CFR 4011.11 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 9 2011-07-01 2011-07-01 false OMB control number. 4011.11 Section 4011.11 Labor... DISCLOSURE REQUIREMENTS DISCLOSURE TO PARTICIPANTS § 4011.11 OMB control number. The collections of... number 1212-0050. ...

12 CFR 1807.106 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 9 2013-01-01 2013-01-01 false OMB control number. 1807.106 Section 1807.106... MAGNET FUND General Provisions § 1807.106 OMB control number. The collection of information requirements... number 1559-0036. ...

Validation of gamma irradiator controls for quality and regulatory compliance

NASA Astrophysics Data System (ADS)

Harding, Rorry B.; Pinteric, Francis J. A.

1995-09-01

Since 1978 the U.S. Food and Drug Administration (FDA) has had both the legal authority and the Current Good Manufacturing Practice (CGMP) regulations in place to require irradiator owners who process medical devices to produce evidence of Irradiation Process Validation. One of the key components of Irradiation Process Validation is the validation of the irradiator controls. However, it is only recently that FDA audits have focused on this component of the process validation. What is Irradiator Control System Validation? What constitutes evidence of control? How do owners obtain evidence? What is the irradiator supplier's role in validation? How does the ISO 9000 Quality Standard relate to the FDA's CGMP requirement for evidence of Control System Validation? This paper presents answers to these questions based on the recent experiences of Nordion's engineering and product management staff who have worked with several US-based irradiator owners. This topic — Validation of Irradiator Controls — is a significant regulatory compliance and operations issue within the irradiator suppliers' and users' community.

29 CFR 4203.6 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 9 2012-07-01 2012-07-01 false OMB control number. 4203.6 Section 4203.6 Labor Regulations... PLANS EXTENSION OF SPECIAL WITHDRAWAL LIABILITY RULES § 4203.6 OMB control number. The collections of... number 1212-0050. ...

29 CFR 4203.6 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 9 2013-07-01 2013-07-01 false OMB control number. 4203.6 Section 4203.6 Labor Regulations... PLANS EXTENSION OF SPECIAL WITHDRAWAL LIABILITY RULES § 4203.6 OMB control number. The collections of... number 1212-0050. ...

29 CFR 4203.6 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 9 2011-07-01 2011-07-01 false OMB control number. 4203.6 Section 4203.6 Labor Regulations... PLANS EXTENSION OF SPECIAL WITHDRAWAL LIABILITY RULES § 4203.6 OMB control number. The collections of... number 1212-0050. ...

29 CFR 4203.6 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false OMB control number. 4203.6 Section 4203.6 Labor Regulations... PLANS EXTENSION OF SPECIAL WITHDRAWAL LIABILITY RULES § 4203.6 OMB control number. The collections of... number 1212-0050. ...

Servo-hydraulic actuator in controllable canonical form: Identification and experimental validation

NASA Astrophysics Data System (ADS)

Maghareh, Amin; Silva, Christian E.; Dyke, Shirley J.

2018-02-01

Hydraulic actuators have been widely used to experimentally examine structural behavior at multiple scales. Real-time hybrid simulation (RTHS) is one innovative testing method that largely relies on such servo-hydraulic actuators. In RTHS, interface conditions must be enforced in real time, and controllers are often used to achieve tracking of the desired displacements. Thus, neglecting the dynamics of hydraulic transfer system may result either in system instability or sub-optimal performance. Herein, we propose a nonlinear dynamical model for a servo-hydraulic actuator (a.k.a. hydraulic transfer system) coupled with a nonlinear physical specimen. The nonlinear dynamical model is transformed into controllable canonical form for further tracking control design purposes. Through a number of experiments, the controllable canonical model is validated.

7 CFR 75.49 - OMB control numbers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false OMB control numbers. 75.49 Section 75.49 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... numbers. The control number assigned to the information collection requirements by the Office of...

Dynamics of Active Separation Control at High Reynolds Numbers

NASA Technical Reports Server (NTRS)

Pack, LaTunia G.; Seifert, Avi

2000-01-01

A series of active flow control experiments were recently conducted at high Reynolds numbers on a generic separated configuration. The model simulates the upper surface of a 20% thick Glauert-Goldschmied type airfoil at zero angle of attack. The flow is fully turbulent since the tunnel sidewall boundary layer flows over the model. The main motivation for the experiments is to generate a comprehensive data base for validation of unsteady numerical simulation as a first step in the development of a CFD design tool, without which it would not be possible to effectively utilize the great potential of unsteady flow control. This paper focuses on the dynamics of several key features of the baseline as well as the controlled flow. It was found that the thickness of the upstream boundary layer has a negligible effect on the flow dynamics. It is speculated that separation is caused mainly by the highly convex surface while viscous effects are less important. The two-dimensional separated flow contains unsteady waves centered on a reduced frequency of 0.9, while in the three dimensional separated flow, frequencies around a reduced frequency of 0.3 and 1 are active. Several scenarios of resonant wave interaction take place at the separated shear-layer and in the pressure recovery region. The unstable reduced frequency bands for periodic excitation are centered on 1.5 and 5, but these reduced frequencies are based on the length of the baseline bubble that shortens due to the excitation. The conventional works well for the coherent wave features. Reproduction of these dynamic effects by a numerical simulation would provide benchmark validation.

Dynamics of Active Separation Control at High Reynolds Numbers

NASA Technical Reports Server (NTRS)

Pack, LaTunia G.; Seifert, Avi

2000-01-01

A series of active flow control experiments were recently conducted at high Reynolds numbers on a generic separated configuration. The model simulates the upper surface of a 20% thick Glauert-Goldschmied type airfoil at zero angle of attack. The flow is fully turbulent since the tunnel sidewall boundary layer flows over the model. The main motivation for the experiments is to generate a comprehensive data base for validation of unsteady numerical simulation as a first step in the development of a CFD design tool, without which it would not be possible to effectively utilize the great potential of unsteady flow control. This paper focuses on the dynamics of several key features of the baseline as well as the controlled flow. It was found that the thickness of the upstream boundary layer has a negligible effect on the flow dynamics. It is speculated that separation is caused mainly by the highly convex surface while viscous effects are less important. The two-dimensional separated flow contains unsteady waves centered on a reduced frequency of 0.8, while in the three dimensional separated flow, frequencies around a reduced frequency of 0.3 and 1 are active. Several scenarios of resonant wave interaction take place at the separated shear-layer and in the pressure recovery region. The unstable reduced frequency bands for periodic excitation are centered on 1.5 and 5, but these reduced frequencies are based on the length of the baseline bubble that shortens due to the excitation. The conventional swept wing-scaling works well for the coherent wave features. Reproduction of these dynamic effects by a numerical simulation would provide benchmark validation.

7 CFR 1944.450 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 13 2013-01-01 2013-01-01 false OMB control number. 1944.450 Section 1944.450... number. The reporting and recordkeeping requirements contained in this regulation have ben approved by the Office of Management and Budget and have been assigned OMB control number 0575-0043. Public...

7 CFR 1944.450 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 13 2014-01-01 2013-01-01 true OMB control number. 1944.450 Section 1944.450... number. The reporting and recordkeeping requirements contained in this regulation have ben approved by the Office of Management and Budget and have been assigned OMB control number 0575-0043. Public...

7 CFR 1924.150 - OMB Control Number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 12 2011-01-01 2011-01-01 false OMB Control Number. 1924.150 Section 1924.150... Number. The reporting requirements contained in this subpart have been approved by the Office of Management and Budget (OMB) and have been assigned OMB control number 0575-0164. Public reporting burden for...

7 CFR 1924.150 - OMB Control Number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true OMB Control Number. 1924.150 Section 1924.150... Number. The reporting requirements contained in this subpart have been approved by the Office of Management and Budget (OMB) and have been assigned OMB control number 0575-0164. Public reporting burden for...

7 CFR 1924.150 - OMB Control Number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false OMB Control Number. 1924.150 Section 1924.150... Number. The reporting requirements contained in this subpart have been approved by the Office of Management and Budget (OMB) and have been assigned OMB control number 0575-0164. Public reporting burden for...

7 CFR 70.6 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false OMB control number. 70.6 Section 70.6 Agriculture... number. (a) Purpose. The collecting of information requirements in this part has been approved by the Office of Management and Budget (OMB) and assigned OMB control number 0581-0127. (b) Display. Sections...

32 CFR 635.21 - USACRC control numbers.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true USACRC control numbers. 635.21 Section 635.21 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS LAW ENFORCEMENT REPORTING Offense Reporting § 635.21 USACRC control numbers. (a) Case numbers to support reporting...

16 CFR 1033.2 - Display of control numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Display of control numbers. 1033.2 Section 1033.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL DISPLAY OF CONTROL NUMBERS FOR COLLECTION OF INFORMATION REQUIREMENTS UNDER THE PAPERWORK REDUCTION ACT § 1033.2 Display of control numbers...

7 CFR 1955.100 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) PROPERTY MANAGEMENT Management of Property § 1955.100 OMB control number... Management and Budget and assigned OMB control number 0575-0110. ...

Organizing, Concerns and Control Numbers.

ERIC Educational Resources Information Center

Washington, Gene

A heuristic procedure can be used to teach organizational skills to students of technical writing. Designed to allow students on their own to explore ways that numbers can be used to give a definite shape to technical information, its central feature is a matrix composed of a series of control numbers (horizontal axis) and organizing concerns…

7 CFR 3565.400 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false OMB control number. 3565.400 Section 3565.400 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED RURAL RENTAL HOUSING PROGRAM Project Management § 3565.400 OMB control number...

7 CFR 1940.1000 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true OMB control number. 1940.1000 Section 1940.1000 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS....1000 OMB control number. The collection of information requirements contained in this regulation has...

7 CFR 3565.400 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 15 2012-01-01 2012-01-01 false OMB control number. 3565.400 Section 3565.400 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED RURAL RENTAL HOUSING PROGRAM Project Management § 3565.400 OMB control number...

7 CFR 3565.400 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 15 2011-01-01 2011-01-01 false OMB control number. 3565.400 Section 3565.400 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED RURAL RENTAL HOUSING PROGRAM Project Management § 3565.400 OMB control number...

7 CFR 3565.400 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 15 2013-01-01 2013-01-01 false OMB control number. 3565.400 Section 3565.400 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED RURAL RENTAL HOUSING PROGRAM Project Management § 3565.400 OMB control number...

7 CFR 3565.400 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 15 2014-01-01 2014-01-01 false OMB control number. 3565.400 Section 3565.400 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED RURAL RENTAL HOUSING PROGRAM Project Management § 3565.400 OMB control number...

7 CFR 1280.238 - OMB Control Numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false OMB Control Numbers. 1280.238 Section 1280.238 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING.... The control number for the information requirements assigned by the Office of Management and Budget...

7 CFR 1220.257 - OMB control numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false OMB control numbers. 1220.257 Section 1220.257 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... control number assigned to the information collection requirements by the Office of Management and Budget...

7 CFR 1209.280 - OMB control numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false OMB control numbers. 1209.280 Section 1209.280 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... control number assigned to the information collection requirements by the Office of Management and Budget...

7 CFR 1942.350 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) PROGRAM REGULATIONS (CONTINUED) ASSOCIATIONS Rural Business Enterprise Grants and Television Demonstration Grants § 1942.350 OMB control number. The collection of information requirements in this regulation have been approved by the Office of Management and Budget and have been assigned OMB control number 0575...

7 CFR 1942.350 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) PROGRAM REGULATIONS (CONTINUED) ASSOCIATIONS Rural Business Enterprise Grants and Television Demonstration Grants § 1942.350 OMB control number. The collection of information requirements in this regulation have been approved by the Office of Management and Budget and have been assigned OMB control number 0575...

7 CFR 1942.350 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) PROGRAM REGULATIONS (CONTINUED) ASSOCIATIONS Rural Business Enterprise Grants and Television Demonstration Grants § 1942.350 OMB control number. The collection of information requirements in this regulation have been approved by the Office of Management and Budget and have been assigned OMB control number 0575...

7 CFR 1942.350 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) PROGRAM REGULATIONS (CONTINUED) ASSOCIATIONS Rural Business Enterprise Grants and Television Demonstration Grants § 1942.350 OMB control number. The collection of information requirements in this regulation have been approved by the Office of Management and Budget and have been assigned OMB control number 0575...

Empirical evaluation demonstrated importance of validating biomarkers for early detection of cancer in screening settings to limit the number of false-positive findings.

PubMed

Chen, Hongda; Knebel, Phillip; Brenner, Hermann

2016-07-01

Search for biomarkers for early detection of cancer is a very active area of research, but most studies are done in clinical rather than screening settings. We aimed to empirically evaluate the role of study setting for early detection marker identification and validation. A panel of 92 candidate cancer protein markers was measured in 35 clinically identified colorectal cancer patients and 35 colorectal cancer patients identified at screening colonoscopy. For each case group, we selected 38 controls without colorectal neoplasms at screening colonoscopy. Single-, two- and three-marker combinations discriminating cases and controls were identified in each setting and subsequently validated in the alternative setting. In all scenarios, a higher number of predictive biomarkers were initially detected in the clinical setting, but a substantially lower proportion of identified biomarkers could subsequently be confirmed in the screening setting. Confirmation rates were 50.0%, 84.5%, and 74.2% for one-, two-, and three-marker algorithms identified in the screening setting and were 42.9%, 18.6%, and 25.7% for algorithms identified in the clinical setting. Validation of early detection markers of cancer in a true screening setting is important to limit the number of false-positive findings. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

7 CFR 2201.34 - OMB Control Number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false OMB Control Number. 2201.34 Section 2201.34 Agriculture Regulations of the Department of Agriculture (Continued) LOCAL TELEVISION LOAN GUARANTEE BOARD LOCAL TELEVISION LOAN GUARANTEE PROGRAM-PROGRAM REGULATIONS Loan Guarantees § 2201.34 OMB Control Number...

7 CFR 1778.100 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false OMB control number. 1778.100 Section 1778.100 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) EMERGENCY AND IMMINENT COMMUNITY WATER ASSISTANCE GRANTS § 1778.100 OMB control number...

7 CFR 402.3 - OMB control numbers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 6 2011-01-01 2011-01-01 false OMB control numbers. 402.3 Section 402.3 Agriculture Regulations of the Department of Agriculture (Continued) FEDERAL CROP INSURANCE CORPORATION, DEPARTMENT OF AGRICULTURE CATASTROPHIC RISK PROTECTION ENDORSEMENT § 402.3 OMB control numbers. The information collection...

7 CFR 252.7 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 4 2011-01-01 2011-01-01 false OMB control number. 252.7 Section 252.7 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... approved by the Office of Management and Budget under control number 0584-0325. ...

7 CFR 252.7 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 4 2014-01-01 2014-01-01 false OMB control number. 252.7 Section 252.7 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... approved by the Office of Management and Budget under control number 0584-0325. ...

7 CFR 252.7 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 4 2013-01-01 2013-01-01 false OMB control number. 252.7 Section 252.7 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... approved by the Office of Management and Budget under control number 0584-0325. ...

7 CFR 252.7 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 4 2012-01-01 2012-01-01 false OMB control number. 252.7 Section 252.7 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... approved by the Office of Management and Budget under control number 0584-0325. ...

7 CFR 402.3 - OMB control numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 6 2010-01-01 2010-01-01 false OMB control numbers. 402.3 Section 402.3 Agriculture Regulations of the Department of Agriculture (Continued) FEDERAL CROP INSURANCE CORPORATION, DEPARTMENT OF AGRICULTURE CATASTROPHIC RISK PROTECTION ENDORSEMENT § 402.3 OMB control numbers. The information collection...

7 CFR 457.4 - OMB control numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 6 2010-01-01 2010-01-01 false OMB control numbers. 457.4 Section 457.4 Agriculture Regulations of the Department of Agriculture (Continued) FEDERAL CROP INSURANCE CORPORATION, DEPARTMENT OF AGRICULTURE COMMON CROP INSURANCE REGULATIONS § 457.4 OMB control numbers. The information collection...

45 CFR 1303.24 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START... Current or Prospective Delegate Agencies § 1303.24 OMB control number. The collection of information... of Management and Budget and assigned OMB control number 0980-0242. [58 FR 13019, Mar. 9, 1993] ...

45 CFR 1303.24 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START... Current or Prospective Delegate Agencies § 1303.24 OMB control number. The collection of information... of Management and Budget and assigned OMB control number 0980-0242. [58 FR 13019, Mar. 9, 1993] ...

45 CFR 1303.24 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START... Current or Prospective Delegate Agencies § 1303.24 OMB control number. The collection of information... of Management and Budget and assigned OMB control number 0980-0242. [58 FR 13019, Mar. 9, 1993] ...

45 CFR 1303.24 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START... Current or Prospective Delegate Agencies § 1303.24 OMB control number. The collection of information... of Management and Budget and assigned OMB control number 0980-0242. [58 FR 13019, Mar. 9, 1993] ...

10 CFR 590.100 - OMB Control Numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false OMB Control Numbers. 590.100 Section 590.100 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS General Provisions § 590.100 OMB Control Numbers...

10 CFR 590.100 - OMB Control Numbers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false OMB Control Numbers. 590.100 Section 590.100 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS General Provisions § 590.100 OMB Control Numbers...

10 CFR 590.100 - OMB Control Numbers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false OMB Control Numbers. 590.100 Section 590.100 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS General Provisions § 590.100 OMB Control Numbers...

29 CFR 403.11 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 2 2010-07-01 2010-07-01 false OMB control number. 403.11 Section 403.11 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR LABOR-MANAGEMENT STANDARDS LABOR ORGANIZATION ANNUAL FINANCIAL REPORTS § 403.11 OMB control number. The collecting of information...

Validation of a proposal for evaluating hospital infection control programs.

PubMed

Silva, Cristiane Pavanello Rodrigues; Lacerda, Rúbia Aparecida

2011-02-01

To validate the construct and discriminant properties of a hospital infection prevention and control program. The program consisted of four indicators: technical-operational structure; operational prevention and control guidelines; epidemiological surveillance system; and prevention and control activities. These indicators, with previously validated content, were applied to 50 healthcare institutions in the city of São Paulo, Southeastern Brazil, in 2009. Descriptive statistics were used to characterize the hospitals and indicator scores, and Cronbach's α coefficient was used to evaluate the internal consistency. The discriminant validity was analyzed by comparing indicator scores between groups of hospitals: with versus without quality certification. The construct validity analysis was based on exploratory factor analysis with a tetrachoric correlation matrix. The indicators for the technical-operational structure and epidemiological surveillance presented almost 100% conformity in the whole sample. The indicators for the operational prevention and control guidelines and the prevention and control activities presented internal consistency ranging from 0.67 to 0.80. The discriminant validity of these indicators indicated higher and statistically significant mean conformity scores among the group of institutions with healthcare certification or accreditation processes. In the construct validation, two dimensions were identified for the operational prevention and control guidelines: recommendations for preventing hospital infection and recommendations for standardizing prophylaxis procedures, with good correlation between the analysis units that formed the guidelines. The same was found for the prevention and control activities: interfaces with treatment units and support units were identified. Validation of the measurement properties of the hospital infection prevention and control program indicators made it possible to develop a tool for evaluating these programs

Choosing the Optimal Number of B-spline Control Points (Part 1: Methodology and Approximation of Curves)

NASA Astrophysics Data System (ADS)

Harmening, Corinna; Neuner, Hans

2016-09-01

Due to the establishment of terrestrial laser scanner, the analysis strategies in engineering geodesy change from pointwise approaches to areal ones. These areal analysis strategies are commonly built on the modelling of the acquired point clouds. Freeform curves and surfaces like B-spline curves/surfaces are one possible approach to obtain space continuous information. A variety of parameters determines the B-spline's appearance; the B-spline's complexity is mostly determined by the number of control points. Usually, this number of control points is chosen quite arbitrarily by intuitive trial-and-error-procedures. In this paper, the Akaike Information Criterion and the Bayesian Information Criterion are investigated with regard to a justified and reproducible choice of the optimal number of control points of B-spline curves. Additionally, we develop a method which is based on the structural risk minimization of the statistical learning theory. Unlike the Akaike and the Bayesian Information Criteria this method doesn't use the number of parameters as complexity measure of the approximating functions but their Vapnik-Chervonenkis-dimension. Furthermore, it is also valid for non-linear models. Thus, the three methods differ in their target function to be minimized and consequently in their definition of optimality. The present paper will be continued by a second paper dealing with the choice of the optimal number of control points of B-spline surfaces.

Poison control center - emergency number

MedlinePlus

For a POISON EMERGENCY call: 1-800-222-1222 ANYWHERE IN THE UNITED STATES This national hotline number will let you ... is a free and confidential service. All local poison control centers in the United States use this ...

Automatic control system generation for robot design validation

NASA Technical Reports Server (NTRS)

Bacon, James A. (Inventor); English, James D. (Inventor)

2012-01-01

The specification and drawings present a new method, system and software product for and apparatus for generating a robotic validation system for a robot design. The robotic validation system for the robot design of a robotic system is automatically generated by converting a robot design into a generic robotic description using a predetermined format, then generating a control system from the generic robotic description and finally updating robot design parameters of the robotic system with an analysis tool using both the generic robot description and the control system.

Integrated Resilient Aircraft Control Project Full Scale Flight Validation

NASA Technical Reports Server (NTRS)

Bosworth, John T.

2009-01-01

Objective: Provide validation of adaptive control law concepts through full scale flight evaluation. Technical Approach: a) Engage failure mode - destabilizing or frozen surface. b) Perform formation flight and air-to-air tracking tasks. Evaluate adaptive algorithm: a) Stability metrics. b) Model following metrics. Full scale flight testing provides an ability to validate different adaptive flight control approaches. Full scale flight testing adds credence to NASA's research efforts. A sustained research effort is required to remove the road blocks and provide adaptive control as a viable design solution for increased aircraft resilience.

Building Kindergartners' Number Sense: A Randomized Controlled Study.

PubMed

Jordan, Nancy C; Glutting, Joseph; Dyson, Nancy; Hassinger-Das, Brenna; Irwin, Casey

2012-08-01

Math achievement in elementary school is mediated by performance and growth in number sense during kindergarten. The aim of the present study was to test the effectiveness of a targeted small group number sense intervention for high-risk kindergartners from low-income communities. Children were randomly assigned to one of three groups ( n = 44 in each group): a number sense intervention group, a language intervention group, or a business as usual control group. Accounting for initial skill level in mathematical knowledge, children who received the number sense intervention performed better than controls at immediate post test, with meaningful effects on measures of number competencies and general math achievement. Many of the effects held eight weeks after the intervention was completed, suggesting that children internalized what they had learned. There were no differences between the language and control groups on any math-related measures.

Separation Control at Flight Reynolds Numbers: Lessons Learned and Future Directions

NASA Technical Reports Server (NTRS)

Pack, LaTunia G.; Seifert, Avi

2000-01-01

Active separation control, using periodic excitation, was studied experimentally at high Reynolds numbers. The effects of compressibility, mild sweep, location of excitation slot and steady momentum transfer on the efficacy of the method were identified. Tests conducted at chord Reynolds numbers as high as 40 x 10(exp 6) demonstrated that active control using oscillatory flow excitation can effectively delay flow separation from, and reattach separated flow to aerodynamic surfaces at flight conditions. The effective frequencies generate one to four vortices over the controlled region at all times, regardless of the Reynolds number. The vortices are initially amplified by the separated shear-layer, and after initiating reattachment, the strength of the vortices decay as they are convected downstream. Large amplitude, low frequency vortices break down to smaller ones upon introduction at the excitation slot. The effects of steady mass transfer were compared to those of periodic excitation. It was found that steady blowing is significantly inferior to periodic excitation in terms of performance benefits and that the response to steady blowing is abrupt, and therefore undesirable from a control point of view. Steady suction and periodic excitation are comparable in effectiveness and both exhibit a gradual response to changes in the magnitude of the control input. The combination of weak steady suction and periodic excitation is extremely effective while the addition of steady blowing could be detrimental. Compressibility effects are weak as long as separation is not caused by a shock-wave/boundary-layer interaction. The undesirable effects of the shock-induced separation could be alleviated by the introduction of periodic excitation upstream of the shock wave, inside the region of supersonic flow. The effects of mild sweep were also studied and periodic excitation was found to be very effective in reattaching three-dimensional separated flow. Scaling laws that

Separation Control at Flight Reynolds Numbers: Lessons Learned and Future Directions

NASA Technical Reports Server (NTRS)

Seifert, Avi; Pack, LaTunia G.

2000-01-01

Active separation control, using periodic excitation, was studied experimentally at high Reynolds numbers. The effects of compressibility, mild sweep, location o excitation slot and steady momentum transfer on the efficacy of the method were identified. Tests conducted at chord Reynolds numbers as high as 40 x 10(exp 6) demonstrated that active control using oscillatory flow excitation can effectively delay flow separation from and reattach separated flow to aerodynamic surfaces at flight conditions. The effective frequencies generate one to four vortices over the controlled region at all times, regardless of the Reynolds number. The vortices are initially amplified by the separated shear-layer, and after initiating reattachment, the strength of the vortices decay as they are convected downstream. Large amplitude, low frequency vortices break down to smaller ones upon introduction at the excitation slot. The effects of steady mass transfer were compared to those of periodic excitation. It was found that steady blowing is significantly inferior to periodic excitation in terms o performance benefits and that the response to steady blowing is abrupt, and therefore undesirable from a control point of view. Steady suction and periodic excitation are comparable in effectiveness and both exhibit a gradual response to changes in the magnitude of the control input. The combination of weak steady suction and periodic excitation is extremely effective while the addition of steady blowing could be detrimental. Compressibility effects are weak as long as separation is not caused by a shock-wave/boundary-layer interaction The undesirable effects of the shock-induced separation could be alleviated by the introduction of periodic excitation upstream of the shock wave, inside the region of supersonic flow. The effects of mild sweep were also studied and periodic excitation was found to be very effective in reattaching three-dimensional separated flow. Scaling laws that correlate 2D

Validation of a motor activity system by a robotically controlled vehicle and using standard reference compounds.

PubMed

Patterson, John P; Markgraf, Carrie G; Cirino, Maria; Bass, Alan S

2005-01-01

A series of experiments were undertaken to evaluate the accuracy, precision, specificity, and sensitivity of an automated, infrared photo beam-based open field motor activity system, the MotorMonitor v. 4.01, Hamilton-Kinder, LLC, for use in a good laboratory practices (GLP) Safety Pharmacology laboratory. This evaluation consisted of two phases: (1) system validation, employing known inputs using the EM-100 Controller Photo Beam Validation System, a robotically controlled vehicle representing a rodent and (2) biologic validation, employing groups of rats treated with the standard pharmacologic agents diazepam or D-amphetamine. The MotorMonitor's parameters that described the open-field activity of a subject were: basic movements, total distance, fine movements, x/y horizontal ambulations, rearing, and total rest time. These measurements were evaluated over a number of zones within each enclosure. System validation with the EM-100 Controller Photo Beam Validation System showed that all the parameters accurately and precisely measured what they were intended to measure, with the exception of fine movements and x/y ambulations. Biologic validation using the central nervous system depressant diazepam at 1, 2, or 5 mg/kg, i.p. produced the expected dose-dependent reduction in rat motor activity. In contrast, the central nervous system stimulant D-amphetamine produced the expected increases in rat motor activity at 0.1 and 1 mg/kg, i.p, demonstrating the specificity and sensitivity of the system. Taken together, these studies of the accuracy, precision, specificity, and sensitivity show the importance of both system and biologic validation in the evaluation of an automated open field motor activity system for use in a GLP compliant laboratory.

Building Kindergartners’ Number Sense: A Randomized Controlled Study

PubMed Central

Jordan, Nancy C.; Glutting, Joseph; Dyson, Nancy; Hassinger-Das, Brenna; Irwin, Casey

2015-01-01

Math achievement in elementary school is mediated by performance and growth in number sense during kindergarten. The aim of the present study was to test the effectiveness of a targeted small group number sense intervention for high-risk kindergartners from low-income communities. Children were randomly assigned to one of three groups (n = 44 in each group): a number sense intervention group, a language intervention group, or a business as usual control group. Accounting for initial skill level in mathematical knowledge, children who received the number sense intervention performed better than controls at immediate post test, with meaningful effects on measures of number competencies and general math achievement. Many of the effects held eight weeks after the intervention was completed, suggesting that children internalized what they had learned. There were no differences between the language and control groups on any math-related measures. PMID:25866417

13 CFR 500.214 - OMB control number. [Reserved

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false OMB control number. [Reserved] 500.214 Section 500.214 Business Credit and Assistance EMERGENCY OIL AND GAS GUARANTEED LOAN BOARD EMERGENCY OIL AND GAS GUARANTEED LOAN PROGRAM Oil and Gas Guaranteed Loans § 500.214 OMB control number...

12 CFR 1806.105 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... ENTERPRISE AWARD PROGRAM General Provisions § 1806.105 OMB control number. The collection of information requirements in this part have been approved by the Office of Management and Budget and assigned OMB control...

12 CFR 1806.105 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... ENTERPRISE AWARD PROGRAM General Provisions § 1806.105 OMB control number. The collection of information requirements in this part have been approved by the Office of Management and Budget and assigned OMB control...

12 CFR 1806.105 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... ENTERPRISE AWARD PROGRAM General Provisions § 1806.105 OMB control number. The collection of information requirements in this part have been approved by the Office of Management and Budget and assigned OMB control...

12 CFR 1806.105 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... ENTERPRISE AWARD PROGRAM General Provisions § 1806.105 OMB control number. The collection of information requirements in this part have been approved by the Office of Management and Budget and assigned OMB control...

12 CFR 1806.105 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... ENTERPRISE AWARD PROGRAM General Provisions § 1806.105 OMB control number. The collection of information requirements in this part have been approved by the Office of Management and Budget and assigned OMB control...

NREL and CSIRO Validating Advanced Microgrid Control Solution | Energy

Science.gov Websites

Organisation NREL and CSIRO Validating Advanced Microgrid Control Solution Australia's Commonwealth Scientific microgrid control solution. This technology helps hybrid microgrids to automatically recognize when solar

Micropillars with a controlled number of site-controlled quantum dots

NASA Astrophysics Data System (ADS)

Kaganskiy, Arsenty; Gericke, Fabian; Heuser, Tobias; Heindel, Tobias; Porte, Xavier; Reitzenstein, Stephan

2018-02-01

We report on the realization of micropillars with site-controlled quantum dots (SCQDs) in the active layer. The SCQDs are grown via the buried stressor approach which allows for the positioned growth and device integration of a controllable number of QDs with high optical quality. This concept is very powerful as the number and the position of SCQDs in the cavity can be simultaneously controlled by the design of the buried-stressor. The fabricated micropillars exhibit a high degree of position control for the QDs above the buried stressor and Q-factors of up to 12 000 at an emission wavelength of around 930 nm. We experimentally analyze and numerically model the cavity Q-factor, the mode volume, the Purcell factor, and the photon-extraction efficiency as a function of the aperture diameter of the buried stressor. Exploiting these SCQD micropillars, we experimentally observe a Purcell enhancement in the single-QD regime with FP = 4.3 ± 0.3.

7 CFR 1205.541 - OMB control numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false OMB control numbers. 1205.541 Section 1205.541 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... number assigned to the information collection requirements by the Office of Management and Budget...

Ada Compiler Validation Summary Report: Certificate Number: 910517W1.11155, Verdix Corporation, VADS UNIX System V/486, SCO UNIX 3.2, VAda-110-3232, Version 6.0, Zenith Z-486/25E (SCO UNIX i386 Release 3.2)

DTIC Science & Technology

1991-10-15

Host Customer Agreement Number: 91-03-18- VRX See Section 3.1 for any additional information about the testing environment. As a result of this validation...Department of Defense Washington DC 20301 AVF Control Number: AVF-VSR-470-0491 15-October-1991 91-03-18- VRx Ada COMPILER VALIDATION SUMMARY REPORT

AdA Compiler Validation Summary Report: Certificate Number: 910920W1. 11214 Verdix Corporation, VADS VAX VMS= AMD 29K, VAda-110-03525, Version 6.04, MicroVAX 3600 (Host) to Ironics IV9001 Board (Target). MVME147 (Target)

DTIC Science & Technology

1991-09-20

Agreement Number: 91-07-16- VRX See section 3.1 for any additional information about the testing environment. As a result of this validation effort...Washington DC 20301 92-06991 AVF Control Number: AVF-VSR-511.0292 18 February 1992 91-07-16- VRX Ada COMPILER VALIDATION SUMMARY REPORT: Certificate Number...System: Ironics IV9001 board (AMD 29000) (Am29000 bare VME machine) Customer Agreement Number: 91-07-16- VRX See section 3.1 for any additional information

7 CFR 249.27 - OMB Control Number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false OMB Control Number. 249.27 Section 249.27 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... approved by the Office of Management and Budget (OMB). The OMB approval number is 0584-0541. [72 FR 13671...

Evaluation of biologic occupational risk control practices: quality indicators development and validation.

PubMed

Takahashi, Renata Ferreira; Gryschek, Anna Luíza F P L; Izumi Nichiata, Lúcia Yasuko; Lacerda, Rúbia Aparecida; Ciosak, Suely Itsuko; Gir, Elucir; Padoveze, Maria Clara

2010-05-01

There is growing demand for the adoption of qualification systems for health care practices. This study is aimed at describing the development and validation of indicators for evaluation of biologic occupational risk control programs. The study involved 3 stages: (1) setting up a research team, (2) development of indicators, and (3) validation of the indicators by a team of specialists recruited to validate each attribute of the developed indicators. The content validation method was used for the validation, and a psychometric scale was developed for the specialists' assessment. A consensus technique was used, and every attribute that obtained a Content Validity Index of at least 0.75 was approved. Eight indicators were developed for the evaluation of the biologic occupational risk prevention program, with emphasis on accidents caused by sharp instruments and occupational tuberculosis prevention. The indicators included evaluation of the structure, process, and results at the prevention and biologic risk control levels. The majority of indicators achieved a favorable consensus regarding all validated attributes. The developed indicators were considered validated, and the method used for construction and validation proved to be effective. Copyright (c) 2010 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

Validation of acid washes as critical control points in hazard analysis and critical control point systems.

PubMed

Dormedy, E S; Brashears, M M; Cutter, C N; Burson, D E

2000-12-01

A 2% lactic acid wash used in a large meat-processing facility was validated as an effective critical control point (CCP) in a hazard analysis and critical control point (HACCP) plan. We examined the microbial profiles of beef carcasses before the acid wash, beef carcasses immediately after the acid wash, beef carcasses 24 h after the acid wash, beef subprimal cuts from the acid-washed carcasses, and on ground beef made from acid-washed carcasses. Total mesophilic, psychrotrophic, coliforms, generic Escherichia coli, lactic acid bacteria, pseudomonads, and acid-tolerant microorganisms were enumerated on all samples. The presence of Salmonella spp. was also determined. Acid washing significantly reduced all counts except for pseudomonads that were present at very low numbers before acid washing. All other counts continued to stay significantly lower (P < 0.05) than those on pre-acid-washed carcasses throughout all processing steps. Total bacteria, coliforms, and generic E. coli enumerated on ground beef samples were more than 1 log cycle lower than those reported in the U.S. Department of Agriculture Baseline data. This study suggests that acid washes may be effective CCPs in HACCP plans and can significantly reduce the total number of microorganisms present on the carcass and during further processing.

7 CFR 1924.150 - OMB Control Number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false OMB Control Number. 1924.150 Section 1924.150 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... REGULATIONS CONSTRUCTION AND REPAIR Planning and Performing Site Development Work § 1924.150 OMB Control...

Towards Validation of an Adaptive Flight Control Simulation Using Statistical Emulation

NASA Technical Reports Server (NTRS)

He, Yuning; Lee, Herbert K. H.; Davies, Misty D.

2012-01-01

Traditional validation of flight control systems is based primarily upon empirical testing. Empirical testing is sufficient for simple systems in which a.) the behavior is approximately linear and b.) humans are in-the-loop and responsible for off-nominal flight regimes. A different possible concept of operation is to use adaptive flight control systems with online learning neural networks (OLNNs) in combination with a human pilot for off-nominal flight behavior (such as when a plane has been damaged). Validating these systems is difficult because the controller is changing during the flight in a nonlinear way, and because the pilot and the control system have the potential to co-adapt in adverse ways traditional empirical methods are unlikely to provide any guarantees in this case. Additionally, the time it takes to find unsafe regions within the flight envelope using empirical testing means that the time between adaptive controller design iterations is large. This paper describes a new concept for validating adaptive control systems using methods based on Bayesian statistics. This validation framework allows the analyst to build nonlinear models with modal behavior, and to have an uncertainty estimate for the difference between the behaviors of the model and system under test.

Poison control center - Emergency number (image)

MedlinePlus

For a poison emergency call 1-800-222-1222 anywhere in the United States. This national hotline number will let you ... is a free and confidential service. All local poison control centers in the U.S. use this national ...

Validation results of specifications for motion control interoperability

NASA Astrophysics Data System (ADS)

Szabo, Sandor; Proctor, Frederick M.

1997-01-01

The National Institute of Standards and Technology (NIST) is participating in the Department of Energy Technologies Enabling Agile Manufacturing (TEAM) program to establish interface standards for machine tool, robot, and coordinate measuring machine controllers. At NIST, the focus is to validate potential application programming interfaces (APIs) that make it possible to exchange machine controller components with a minimal impact on the rest of the system. This validation is taking place in the enhanced machine controller (EMC) consortium and is in cooperation with users and vendors of motion control equipment. An area of interest is motion control, including closed-loop control of individual axes and coordinated path planning. Initial tests of the motion control APIs are complete. The APIs were implemented on two commercial motion control boards that run on two different machine tools. The results for a baseline set of APIs look promising, but several issues were raised. These include resolving differing approaches in how motions are programmed and defining a standard measurement of performance for motion control. This paper starts with a summary of the process used in developing a set of specifications for motion control interoperability. Next, the EMC architecture and its classification of motion control APIs into two classes, Servo Control and Trajectory Planning, are reviewed. Selected APIs are presented to explain the basic functionality and some of the major issues involved in porting the APIs to other motion controllers. The paper concludes with a summary of the main issues and ways to continue the standards process.

12 CFR 18.1 - Purpose and OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... statement with narrative information management deems important. The availability of this information is... AND OTHER INFORMATION BY NATIONAL BANKS § 18.1 Purpose and OMB control number. (a) Purpose. The... public confidence in the national banking system. (b) OMB control number. The collection of information...

12 CFR 18.1 - Purpose and OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... statement with narrative information management deems important. The availability of this information is... AND OTHER INFORMATION BY NATIONAL BANKS § 18.1 Purpose and OMB control number. (a) Purpose. The... public confidence in the national banking system. (b) OMB control number. The collection of information...

12 CFR 18.1 - Purpose and OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... statement with narrative information management deems important. The availability of this information is... AND OTHER INFORMATION BY NATIONAL BANKS § 18.1 Purpose and OMB control number. (a) Purpose. The... public confidence in the national banking system. (b) OMB control number. The collection of information...

12 CFR 18.1 - Purpose and OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... statement with narrative information management deems important. The availability of this information is... AND OTHER INFORMATION BY NATIONAL BANKS § 18.1 Purpose and OMB control number. (a) Purpose. The... public confidence in the national banking system. (b) OMB control number. The collection of information...

8 CFR 207.6 - Control over approved refugee numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Control over approved refugee numbers. 207.6 Section 207.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADMISSION OF REFUGEES § 207.6 Control over approved refugee numbers. Current numerical accounting of...

8 CFR 207.6 - Control over approved refugee numbers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Control over approved refugee numbers. 207.6 Section 207.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADMISSION OF REFUGEES § 207.6 Control over approved refugee numbers. Current numerical accounting of...

8 CFR 207.6 - Control over approved refugee numbers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Control over approved refugee numbers. 207.6 Section 207.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADMISSION OF REFUGEES § 207.6 Control over approved refugee numbers. Current numerical accounting of...

8 CFR 207.6 - Control over approved refugee numbers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Control over approved refugee numbers. 207.6 Section 207.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADMISSION OF REFUGEES § 207.6 Control over approved refugee numbers. Current numerical accounting of...

8 CFR 207.6 - Control over approved refugee numbers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Control over approved refugee numbers. 207.6 Section 207.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADMISSION OF REFUGEES § 207.6 Control over approved refugee numbers. Current numerical accounting of...

7 CFR 1218.78 - OMB control numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false OMB control numbers. 1218.78 Section 1218.78 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Management and Budget pursuant to the Paperwork Reduction Act of 1995, 44 U.S.C. Chapter 35, is OMB control...

7 CFR 1212.88 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false OMB control number. 1212.88 Section 1212.88 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Management and Budget pursuant to the Paperwork Reduction Act of 1995, 44 U.S.C. Chapter 35, is OMB control...

Control Oriented Modeling and Validation of Aeroservoelastic Systems

NASA Technical Reports Server (NTRS)

Crowder, Marianne; deCallafon, Raymond (Principal Investigator)

2002-01-01

Lightweight aircraft design emphasizes the reduction of structural weight to maximize aircraft efficiency and agility at the cost of increasing the likelihood of structural dynamic instabilities. To ensure flight safety, extensive flight testing and active structural servo control strategies are required to explore and expand the boundary of the flight envelope. Aeroservoelastic (ASE) models can provide online flight monitoring of dynamic instabilities to reduce flight time testing and increase flight safety. The success of ASE models is determined by the ability to take into account varying flight conditions and the possibility to perform flight monitoring under the presence of active structural servo control strategies. In this continued study, these aspects are addressed by developing specific methodologies and algorithms for control relevant robust identification and model validation of aeroservoelastic structures. The closed-loop model robust identification and model validation are based on a fractional model approach where the model uncertainties are characterized in a closed-loop relevant way.

40 CFR 1065.545 - Validation of proportional flow control for batch sampling.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 34 2013-07-01 2013-07-01 false Validation of proportional flow control for batch sampling. 1065.545 Section 1065.545 Protection of Environment ENVIRONMENTAL PROTECTION... Specified Duty Cycles § 1065.545 Validation of proportional flow control for batch sampling. For any...

40 CFR 1065.545 - Validation of proportional flow control for batch sampling.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 34 2012-07-01 2012-07-01 false Validation of proportional flow control for batch sampling. 1065.545 Section 1065.545 Protection of Environment ENVIRONMENTAL PROTECTION... Specified Duty Cycles § 1065.545 Validation of proportional flow control for batch sampling. For any...

40 CFR 1065.545 - Validation of proportional flow control for batch sampling.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Validation of proportional flow control for batch sampling. 1065.545 Section 1065.545 Protection of Environment ENVIRONMENTAL PROTECTION... Specified Duty Cycles § 1065.545 Validation of proportional flow control for batch sampling. For any...

7 CFR 1220.257 - OMB control numbers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Soybean Promotion and Research Order Miscellaneous § 1220.257 OMB control numbers. The...

7 CFR 4284.1100 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GRANTS Agriculture Innovation Demonstration Centers... have been approved by the Office of Management and Budget and have been assigned OMB control number...

7 CFR 3560.450 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Servicing § 3560.450 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.450 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Servicing § 3560.450 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.350 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Financial Management § 3560.350 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.800 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Appraisals § 3560.800 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.700 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Housing Preservation § 3560.700 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.750 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.750 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.350 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Financial Management § 3560.350 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.800 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Appraisals § 3560.800 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.800 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Appraisals § 3560.800 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.800 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Appraisals § 3560.800 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.750 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.750 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.450 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Servicing § 3560.450 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.800 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Appraisals § 3560.800 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.350 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Financial Management § 3560.350 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.450 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Servicing § 3560.450 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.450 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Servicing § 3560.450 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.350 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Financial Management § 3560.350 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.750 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.750 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.700 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Housing Preservation § 3560.700 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.350 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Financial Management § 3560.350 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.700 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Housing Preservation § 3560.700 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.700 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Housing Preservation § 3560.700 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.750 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.750 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.750 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.750 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.700 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Housing Preservation § 3560.700 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.400 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Agency Monitoring § 3560.400 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.300 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Rental Subsidies § 3560.300 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.250 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Rents § 3560.250 OMB control number. The information... reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and...

7 CFR 3560.400 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Agency Monitoring § 3560.400 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.250 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Rents § 3560.250 OMB control number. The information... reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and...

7 CFR 3560.250 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Rents § 3560.250 OMB control number. The information... reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and...

7 CFR 3560.300 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Rental Subsidies § 3560.300 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.300 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Rental Subsidies § 3560.300 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.300 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Rental Subsidies § 3560.300 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.400 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Agency Monitoring § 3560.400 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.250 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Rents § 3560.250 OMB control number. The information... reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and...

7 CFR 3560.400 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Agency Monitoring § 3560.400 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.250 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Rents § 3560.250 OMB control number. The information... reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and...

7 CFR 3560.300 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Rental Subsidies § 3560.300 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 3560.400 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Agency Monitoring § 3560.400 OMB control number. The... time for reviewing instructions, searching existing data sources, gathering and maintaining the data...

7 CFR 1721.109 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE POST-LOAN POLICIES AND PROCEDURES FOR INSURED ELECTRIC LOANS Extensions of Payments of Principal... approved by the Office of Management and Budget and assigned OMB control number 0572-0123. ...

Development and validation of a melanoma risk score based on pooled data from 16 case-control studies

PubMed Central

Davies, John R; Chang, Yu-mei; Bishop, D Timothy; Armstrong, Bruce K; Bataille, Veronique; Bergman, Wilma; Berwick, Marianne; Bracci, Paige M; Elwood, J Mark; Ernstoff, Marc S; Green, Adele; Gruis, Nelleke A; Holly, Elizabeth A; Ingvar, Christian; Kanetsky, Peter A; Karagas, Margaret R; Lee, Tim K; Le Marchand, Loïc; Mackie, Rona M; Olsson, Håkan; Østerlind, Anne; Rebbeck, Timothy R; Reich, Kristian; Sasieni, Peter; Siskind, Victor; Swerdlow, Anthony J; Titus, Linda; Zens, Michael S; Ziegler, Andreas; Gallagher, Richard P.; Barrett, Jennifer H; Newton-Bishop, Julia

2015-01-01

Background We report the development of a cutaneous melanoma risk algorithm based upon 7 factors; hair colour, skin type, family history, freckling, nevus count, number of large nevi and history of sunburn, intended to form the basis of a self-assessment webtool for the general public. Methods Predicted odds of melanoma were estimated by analysing a pooled dataset from 16 case-control studies using logistic random coefficients models. Risk categories were defined based on the distribution of the predicted odds in the controls from these studies. Imputation was used to estimate missing data in the pooled datasets. The 30th, 60th and 90th centiles were used to distribute individuals into four risk groups for their age, sex and geographic location. Cross-validation was used to test the robustness of the thresholds for each group by leaving out each study one by one. Performance of the model was assessed in an independent UK case-control study dataset. Results Cross-validation confirmed the robustness of the threshold estimates. Cases and controls were well discriminated in the independent dataset (area under the curve 0.75, 95% CI 0.73-0.78). 29% of cases were in the highest risk group compared with 7% of controls, and 43% of controls were in the lowest risk group compared with 13% of cases. Conclusion We have identified a composite score representing an estimate of relative risk and successfully validated this score in an independent dataset. Impact This score may be a useful tool to inform members of the public about their melanoma risk. PMID:25713022

In-Trail Procedure Air Traffic Control Procedures Validation Simulation Study

NASA Technical Reports Server (NTRS)

Chartrand, Ryan C.; Hewitt, Katrin P.; Sweeney, Peter B.; Graff, Thomas J.; Jones, Kenneth M.

2012-01-01

In August 2007, Airservices Australia (Airservices) and the United States National Aeronautics and Space Administration (NASA) conducted a validation experiment of the air traffic control (ATC) procedures associated with the Automatic Dependant Surveillance-Broadcast (ADS-B) In-Trail Procedure (ITP). ITP is an Airborne Traffic Situation Awareness (ATSA) application designed for near-term use in procedural airspace in which ADS-B data are used to facilitate climb and descent maneuvers. NASA and Airservices conducted the experiment in Airservices simulator in Melbourne, Australia. Twelve current operational air traffic controllers participated in the experiment, which identified aspects of the ITP that could be improved (mainly in the communication and controller approval process). Results showed that controllers viewed the ITP as valid and acceptable. This paper describes the experiment design and results.

7 CFR 3560.600 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Off-Farm Labor Housing § 3560.600 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3550.50 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS General § 3550.50 OMB control number. The... average of 11/2 hours per response, including time for reviewing instructions, searching existing data...

7 CFR 3560.650 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS On-Farm Labor Housing § 3560.650 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.650 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS On-Farm Labor Housing § 3560.650 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.600 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Off-Farm Labor Housing § 3560.600 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.600 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Off-Farm Labor Housing § 3560.600 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3550.50 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS General § 3550.50 OMB control number. The... average of 11/2 hours per response, including time for reviewing instructions, searching existing data...

7 CFR 3550.50 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS General § 3550.50 OMB control number. The... average of 11/2 hours per response, including time for reviewing instructions, searching existing data...

7 CFR 3550.50 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS General § 3550.50 OMB control number. The... average of 11/2 hours per response, including time for reviewing instructions, searching existing data...

7 CFR 3550.50 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS General § 3550.50 OMB control number. The... average of 11/2 hours per response, including time for reviewing instructions, searching existing data...

7 CFR 3560.600 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Off-Farm Labor Housing § 3560.600 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.650 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS On-Farm Labor Housing § 3560.650 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.600 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Off-Farm Labor Housing § 3560.600 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.650 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS On-Farm Labor Housing § 3560.650 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

7 CFR 3560.650 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS On-Farm Labor Housing § 3560.650 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

NREL, EPRI Validate Advanced Microgrid Controller with ESIF's Virtual

Science.gov Websites

Microgrid Controller with ESIF's Virtual Microgrid Model NREL, EPRI Validate Advanced Microgrid Controller with ESIF's Virtual Microgrid Model NREL is working with the Electric Power Research Institute (EPRI Energy Systems Integration Facility, by connecting it to a virtual model of a microgrid. NREL researchers

7 CFR 3550.250 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Special Servicing § 3550.250 OMB control number. The... average of 11/2 hours per response, including time for reviewing insurrections, searching existing data...

7 CFR 3550.250 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Special Servicing § 3550.250 OMB control number. The... average of 11/2 hours per response, including time for reviewing insurrections, searching existing data...

7 CFR 3550.200 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Regular Servicing § 3550.200 OMB control number. The... average of 11/2 hours per response, including time for reviewing instructions, searching existing data...

7 CFR 3550.250 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Special Servicing § 3550.250 OMB control number. The... average of 11/2 hours per response, including time for reviewing insurrections, searching existing data...

7 CFR 3550.200 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Regular Servicing § 3550.200 OMB control number. The... average of 11/2 hours per response, including time for reviewing instructions, searching existing data...

7 CFR 3550.200 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Regular Servicing § 3550.200 OMB control number. The... average of 11/2 hours per response, including time for reviewing instructions, searching existing data...

7 CFR 3550.200 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Regular Servicing § 3550.200 OMB control number. The... average of 11/2 hours per response, including time for reviewing instructions, searching existing data...

7 CFR 3550.250 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Special Servicing § 3550.250 OMB control number. The... average of 11/2 hours per response, including time for reviewing insurrections, searching existing data...

7 CFR 3550.250 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Special Servicing § 3550.250 OMB control number. The... average of 11/2 hours per response, including time for reviewing insurrections, searching existing data...

7 CFR 3550.200 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Regular Servicing § 3550.200 OMB control number. The... average of 11/2 hours per response, including time for reviewing instructions, searching existing data...

7 CFR 56.9 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) VOLUNTARY GRADING OF SHELL EGGS Grading of Shell Eggs General § 56.9 OMB control number. (a) Purpose. The collecting of...

7 CFR 3550.300 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Post-Servicing Actions § 3550.300 OMB control number..., with an average of 11/2 hours per response, including time for review instructions, searching existing...

7 CFR 3550.300 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Post-Servicing Actions § 3550.300 OMB control number..., with an average of 11/2 hours per response, including time for review instructions, searching existing...

7 CFR 3550.300 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Post-Servicing Actions § 3550.300 OMB control number..., with an average of 11/2 hours per response, including time for review instructions, searching existing...

7 CFR 3550.300 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Post-Servicing Actions § 3550.300 OMB control number..., with an average of 11/2 hours per response, including time for review instructions, searching existing...

7 CFR 3550.300 - OMB control number.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Post-Servicing Actions § 3550.300 OMB control number..., with an average of 11/2 hours per response, including time for review instructions, searching existing...

Getting DNA copy numbers without control samples.

PubMed

Ortiz-Estevez, Maria; Aramburu, Ander; Rubio, Angel

2012-08-16

The selection of the reference to scale the data in a copy number analysis has paramount importance to achieve accurate estimates. Usually this reference is generated using control samples included in the study. However, these control samples are not always available and in these cases, an artificial reference must be created. A proper generation of this signal is crucial in terms of both noise and bias.We propose NSA (Normality Search Algorithm), a scaling method that works with and without control samples. It is based on the assumption that genomic regions enriched in SNPs with identical copy numbers in both alleles are likely to be normal. These normal regions are predicted for each sample individually and used to calculate the final reference signal. NSA can be applied to any CN data regardless the microarray technology and preprocessing method. It also finds an optimal weighting of the samples minimizing possible batch effects. Five human datasets (a subset of HapMap samples, Glioblastoma Multiforme (GBM), Ovarian, Prostate and Lung Cancer experiments) have been analyzed. It is shown that using only tumoral samples, NSA is able to remove the bias in the copy number estimation, to reduce the noise and therefore, to increase the ability to detect copy number aberrations (CNAs). These improvements allow NSA to also detect recurrent aberrations more accurately than other state of the art methods. NSA provides a robust and accurate reference for scaling probe signals data to CN values without the need of control samples. It minimizes the problems of bias, noise and batch effects in the estimation of CNs. Therefore, NSA scaling approach helps to better detect recurrent CNAs than current methods. The automatic selection of references makes it useful to perform bulk analysis of many GEO or ArrayExpress experiments without the need of developing a parser to find the normal samples or possible batches within the data. The method is available in the open-source R package

Verification and Validation of Digitally Upgraded Control Rooms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boring, Ronald; Lau, Nathan

2015-09-01

As nuclear power plants undertake main control room modernization, a challenge is the lack of a clearly defined human factors process to follow. Verification and validation (V&V) as applied in the nuclear power community has tended to involve efforts such as integrated system validation, which comes at the tail end of the design stage. To fill in guidance gaps and create a step-by-step process for control room modernization, we have developed the Guideline for Operational Nuclear Usability and Knowledge Elicitation (GONUKE). This approach builds on best practices in the software industry, which prescribe an iterative user-centered approach featuring multiple cyclesmore » of design and evaluation. Nuclear regulatory guidance for control room design emphasizes summative evaluation—which occurs after the design is complete. In the GONUKE approach, evaluation is also performed at the formative stage of design—early in the design cycle using mockups and prototypes for evaluation. The evaluation may involve expert review (e.g., software heuristic evaluation at the formative stage and design verification against human factors standards like NUREG-0700 at the summative stage). The evaluation may also involve user testing (e.g., usability testing at the formative stage and integrated system validation at the summative stage). An additional, often overlooked component of evaluation is knowledge elicitation, which captures operator insights into the system. In this report we outline these evaluation types across design phases that support the overall modernization process. The objective is to provide industry-suitable guidance for steps to be taken in support of the design and evaluation of a new human-machine interface (HMI) in the control room. We suggest the value of early-stage V&V and highlight how this early-stage V&V can help improve the design process for control room modernization. We argue that there is a need to overcome two shortcomings of V&V in current

High-Reynolds Number Circulation Control Testing in the National Transonic Facility

NASA Technical Reports Server (NTRS)

Milholen, William E., II; Jones, Gregory S.; Chan, David T.; Goodliff, Scott L.

2012-01-01

A new capability to test active flow control concepts and propulsion simulations at high Reynolds numbers in the National Transonic Facility at the NASA Langley Research Center is being developed. The first active flow control experiment was completed using the new FAST-MAC semi-span model to study Reynolds number scaling effects for several circulation control concepts. Testing was conducted over a wide range of Mach numbers, up to chord Reynolds numbers of 30 million. The model was equipped with four onboard flow control valves allowing independent control of the circulation control plenums, which were directed over a 15% chord simple-hinged flap. Preliminary analysis of the uncorrected lift data showed that the circulation control increased the low-speed maximum lift coefficient by 33%. At transonic speeds, the circulation control was capable of positively altering the shockwave pattern on the upper wing surface and reducing flow separation. Furthermore, application of the technique to only the outboard portion of the wing demonstrated the feasibility of a pneumatic based roll control capability.

Guidance and Control Systems Simulation and Validation Techniques

DTIC Science & Technology

1988-07-01

AGARDograph No.273 GUIDANCE AND CONTROL SYSTEMS SIMULATION AND VALIDATION TECHNIQUES Edited by Dr William P.Albritton, Jr AMTEC Corporation 213 Ridgelawn...AND DEVELOPMENT PROCESS FOR TACTICAL GUIDED WEAPONS by Dr W.PAlbritton, Jr AMTEC Corporation 213 Ridgelawn Drive Athens, AL 35611, USA Summary A brief

7 CFR 1214.108 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false OMB control number. 1214.108 Section 1214.108 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE CHRISTMAS TREE PROMOTION...

7 CFR 1214.108 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false OMB control number. 1214.108 Section 1214.108 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE CHRISTMAS TREE PROMOTION...

7 CFR 1214.108 - OMB control number.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false OMB control number. 1214.108 Section 1214.108 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE CHRISTMAS TREE PROMOTION...

7 CFR 252.7 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION NATIONAL COMMODITY PROCESSING PROGRAM § 252.7 OMB... approved by the Office of Management and Budget under control number 0584-0325. ...

7 CFR 1209.280 - OMB control numbers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false OMB control numbers. 1209.280 Section 1209.280 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH...

7 CFR 1209.280 - OMB control numbers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false OMB control numbers. 1209.280 Section 1209.280 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH...

7 CFR 1209.280 - OMB control numbers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false OMB control numbers. 1209.280 Section 1209.280 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH...

7 CFR 1209.280 - OMB control numbers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false OMB control numbers. 1209.280 Section 1209.280 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH...

7 CFR 1942.350 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) PROGRAM REGULATIONS (CONTINUED) ASSOCIATIONS Rural Business Enterprise Grants and Television Demonstration... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... been approved by the Office of Management and Budget and have been assigned OMB control number 0575...

Mixing Methods in Randomized Controlled Trials (RCTs): Validation, Contextualization, Triangulation, and Control

ERIC Educational Resources Information Center

Spillane, James P.; Pareja, Amber Stitziel; Dorner, Lisa; Barnes, Carol; May, Henry; Huff, Jason; Camburn, Eric

2010-01-01

In this paper we described how we mixed research approaches in a Randomized Control Trial (RCT) of a school principal professional development program. Using examples from our study we illustrate how combining qualitative and quantitative data can address some key challenges from validating instruments and measures of mediator variables to…

Experimental Validation of L1 Adaptive Control: Rohrs' Counterexample in Flight

NASA Technical Reports Server (NTRS)

Xargay, Enric; Hovakimyan, Naira; Dobrokhodov, Vladimir; Kaminer, Issac; Kitsios, Ioannis; Cao, Chengyu; Gregory, Irene M.; Valavani, Lena

2010-01-01

The paper presents new results on the verification and in-flight validation of an L1 adaptive flight control system, and proposes a general methodology for verification and validation of adaptive flight control algorithms. The proposed framework is based on Rohrs counterexample, a benchmark problem presented in the early 80s to show the limitations of adaptive controllers developed at that time. In this paper, the framework is used to evaluate the performance and robustness characteristics of an L1 adaptive control augmentation loop implemented onboard a small unmanned aerial vehicle. Hardware-in-the-loop simulations and flight test results confirm the ability of the L1 adaptive controller to maintain stability and predictable performance of the closed loop adaptive system in the presence of general (artificially injected) unmodeled dynamics. The results demonstrate the advantages of L1 adaptive control as a verifiable robust adaptive control architecture with the potential of reducing flight control design costs and facilitating the transition of adaptive control into advanced flight control systems.

Getting DNA copy numbers without control samples

PubMed Central

2012-01-01

Background The selection of the reference to scale the data in a copy number analysis has paramount importance to achieve accurate estimates. Usually this reference is generated using control samples included in the study. However, these control samples are not always available and in these cases, an artificial reference must be created. A proper generation of this signal is crucial in terms of both noise and bias. We propose NSA (Normality Search Algorithm), a scaling method that works with and without control samples. It is based on the assumption that genomic regions enriched in SNPs with identical copy numbers in both alleles are likely to be normal. These normal regions are predicted for each sample individually and used to calculate the final reference signal. NSA can be applied to any CN data regardless the microarray technology and preprocessing method. It also finds an optimal weighting of the samples minimizing possible batch effects. Results Five human datasets (a subset of HapMap samples, Glioblastoma Multiforme (GBM), Ovarian, Prostate and Lung Cancer experiments) have been analyzed. It is shown that using only tumoral samples, NSA is able to remove the bias in the copy number estimation, to reduce the noise and therefore, to increase the ability to detect copy number aberrations (CNAs). These improvements allow NSA to also detect recurrent aberrations more accurately than other state of the art methods. Conclusions NSA provides a robust and accurate reference for scaling probe signals data to CN values without the need of control samples. It minimizes the problems of bias, noise and batch effects in the estimation of CNs. Therefore, NSA scaling approach helps to better detect recurrent CNAs than current methods. The automatic selection of references makes it useful to perform bulk analysis of many GEO or ArrayExpress experiments without the need of developing a parser to find the normal samples or possible batches within the data. The method is

9 CFR 355.9 - Numbers granted same ownership or control.

Code of Federal Regulations, 2010 CFR

2010-01-01

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Proceedings of the 2004 Workshop on CFD Validation of Synthetic Jets and Turbulent Separation Control

NASA Technical Reports Server (NTRS)

Rumsey, Christopher L. (Compiler)

2007-01-01

The papers presented here are from the Langley Research Center Workshop on Computational Fluid Dynamics (CFD) Validation of Synthetic Jets and Turbulent Separation Control (nicknamed "CFDVAL2004"), held March 2004 in Williamsburg, Virginia. The goal of the workshop was to bring together an international group of CFD practitioners to assess the current capabilities of different classes of turbulent flow solution methodologies to predict flow fields induced by synthetic jets and separation control geometries. The workshop consisted of three flow-control test cases of varying complexity, and participants could contribute to any number of the cases. Along with their workshop submissions, each participant included a short write-up describing their method for computing the particular case(s). These write-ups are presented as received from the authors with no editing. Descriptions of each of the test cases and experiments are also included.

8 CFR 299.5 - Display of control numbers.

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7 CFR 1212.108 - OMB control number.

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2011-01-01

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Revisiting Turbulence Model Validation for High-Mach Number Axisymmetric Compression Corner Flows

NASA Technical Reports Server (NTRS)

Georgiadis, Nicholas J.; Rumsey, Christopher L.; Huang, George P.

2015-01-01

Two axisymmetric shock-wave/boundary-layer interaction (SWBLI) cases are used to benchmark one- and two-equation Reynolds-averaged Navier-Stokes (RANS) turbulence models. This validation exercise was executed in the philosophy of the NASA Turbulence Modeling Resource and the AIAA Turbulence Model Benchmarking Working Group. Both SWBLI cases are from the experiments of Kussoy and Horstman for axisymmetric compression corner geometries with SWBLI inducing flares of 20 and 30 degrees, respectively. The freestream Mach number was approximately 7. The RANS closures examined are the Spalart-Allmaras one-equation model and the Menter family of kappa - omega two equation models including the Baseline and Shear Stress Transport formulations. The Wind-US and CFL3D RANS solvers are employed to simulate the SWBLI cases. Comparisons of RANS solutions to experimental data are made for a boundary layer survey plane just upstream of the SWBLI region. In the SWBLI region, comparisons of surface pressure and heat transfer are made. The effects of inflow modeling strategy, grid resolution, grid orthogonality, turbulent Prandtl number, and code-to-code variations are also addressed.

7 CFR 1956.150 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

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Code of Federal Regulations, 2010 CFR

2010-01-01

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Code of Federal Regulations, 2010 CFR

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[Econometric and ethical validation of regression logistics. Reducing of the number of patients in the evaluation of mortality].

PubMed

Castiel, D; Herve, C

1992-01-01

In general, a large number of patients is needed to conclude whether the results of a therapeutic strategy are significant or not. One can lower this number with a logit. The method has been proposed in an article published recently (Cost-utility analysis of early thrombolytic therapy, Pharmaco Economics, 1992). The present article is an essay aimed at validating the method, both from the econometric and ethical points of view.

Air & Space Power Journal (ASPJ). Volume 26, Number 6

DTIC Science & Technology

2012-12-01

collection of information if it does not display a currently valid OMB control number. 1. REPORT DATE DEC 2012 2. REPORT TYPE 3. DATES COVERED 00- 11 ...MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11 . SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION/AVAILABILITY...continuous sharing of information among the military services, combatant commands, coalition partners, and intel- ligence community with the goal of

7 CFR 1221.138 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

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7 CFR 1206.78 - OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

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7 CFR 1212.108 - OMB control number.

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2010-01-01

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Validation Methods for Fault-Tolerant avionics and control systems, working group meeting 1

NASA Technical Reports Server (NTRS)

1979-01-01

The proceedings of the first working group meeting on validation methods for fault tolerant computer design are presented. The state of the art in fault tolerant computer validation was examined in order to provide a framework for future discussions concerning research issues for the validation of fault tolerant avionics and flight control systems. The development of positions concerning critical aspects of the validation process are given.

The Validation by Measurement Theory of Proposed Object-Oriented Software Metrics

NASA Technical Reports Server (NTRS)

Neal, Ralph D.

1996-01-01

Moving software development into the engineering arena requires controllability, and to control a process, it must be measurable. Measuring the process does no good if the product is not also measured, i.e., being the best at producing an inferior product does not define a quality process. Also, not every number extracted from software development is a valid measurement. A valid measurement only results when we are able to verify that the number is representative of the attribute that we wish to measure. Many proposed software metrics are used by practitioners without these metrics ever having been validated, leading to costly but often useless calculations. Several researchers have bemoaned the lack of scientific precision in much of the published software measurement work and have called for validation of software metrics by measurement theory. This dissertation applies measurement theory to validate fifty proposed object-oriented software metrics.

Validation Test Report for WAVEWATCH III

DTIC Science & Technology

2012-11-30

scales relevant to operation of a zodiac , to larger length-scales, relevant to activities on the largest ships, such as ship-to-ship transfer of...average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data...display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

75 FR 51503 - Existing Collection in Use Without an OMB Control Number

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-20

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REPRODUCTIVE NUMBERS, EPIDEMIC SPREAD AND CONTROL IN A COMMUNITY OF HOUSEHOLDS

PubMed Central

Goldstein, E.; Paur, K.; Fraser, C.; Kenah, E.; Wallinga, J.; Lipsitch, M.

2009-01-01

Many of the studies on emerging epidemics (such as SARS and pandemic flu) use mass action models to estimate reproductive numbers and the needed control measures. In reality, transmission patterns are more complex due to the presence of various social networks. One level of complexity can be accommodated by considering a community of households. Our study of transmission dynamics in a community of households emphasizes five types of reproductive numbers for the epidemic spread: household-to-household reproductive number, leaky vaccine-associated reproductive numbers, perfect vaccine reproductive number, growth rate reproductive number, and the individual reproductive number. Each of those carries different information about the transmission dynamics and the required control measures, and often some of those can be estimated from the data while others cannot. Simulations have shown that under certain scenarios there is an ordering for those reproductive numbers. We have proven a number of ordering inequalities under general assumptions about the individual infectiousness profiles. Those inequalities allow, for instance, to estimate the needed vaccine coverage and other control measures without knowing the various transmission parameters in the models. Along the way, we’ve also shown that in choosing between increasing vaccine efficacy and increasing coverage levels by the same factor, preference should go to efficacy. PMID:19559715

Validity of the Microsoft Kinect for assessment of postural control.

PubMed

Clark, Ross A; Pua, Yong-Hao; Fortin, Karine; Ritchie, Callan; Webster, Kate E; Denehy, Linda; Bryant, Adam L

2012-07-01

Clinically feasible methods of assessing postural control such as timed standing balance and functional reach tests provide important information, however, they cannot accurately quantify specific postural control mechanisms. The Microsoft Kinect™ system provides real-time anatomical landmark position data in three dimensions (3D), and given that it is inexpensive, portable and simple to setup it may bridge this gap. This study assessed the concurrent validity of the Microsoft Kinect™ against a benchmark reference, a multiple-camera 3D motion analysis system, in 20 healthy subjects during three postural control tests: (i) forward reach, (ii) lateral reach, and (iii) single-leg eyes-closed standing balance. For the reach tests, the outcome measures consisted of distance reached and trunk flexion angle in the sagittal (forward reach) and coronal (lateral reach) planes. For the standing balance test the range and deviation of movement in the anatomical landmark positions for the sternum, pelvis, knee and ankle and the lateral and anterior trunk flexion angle were assessed. The Microsoft Kinect™ and 3D motion analysis systems had comparable inter-trial reliability (ICC difference=0.06±0.05; range, 0.00-0.16) and excellent concurrent validity, with Pearson's r-values >0.90 for the majority of measurements (r=0.96±0.04; range, 0.84-0.99). However, ordinary least products analyses demonstrated proportional biases for some outcome measures associated with the pelvis and sternum. These findings suggest that the Microsoft Kinect™ can validly assess kinematic strategies of postural control. Given the potential benefits it could therefore become a useful tool for assessing postural control in the clinical setting. Copyright © 2012 Elsevier B.V. All rights reserved.

[Validation and verfication of microbiology methods].

PubMed

Camaró-Sala, María Luisa; Martínez-García, Rosana; Olmos-Martínez, Piedad; Catalá-Cuenca, Vicente; Ocete-Mochón, María Dolores; Gimeno-Cardona, Concepción

2015-01-01

Clinical microbiologists should ensure, to the maximum level allowed by the scientific and technical development, the reliability of the results. This implies that, in addition to meeting the technical criteria to ensure their validity, they must be performed with a number of conditions that allows comparable results to be obtained, regardless of the laboratory that performs the test. In this sense, the use of recognized and accepted reference methodsis the most effective tool for these guarantees. The activities related to verification and validation of analytical methods has become very important, as there is continuous development, as well as updating techniques and increasingly complex analytical equipment, and an interest of professionals to ensure quality processes and results. The definitions of validation and verification are described, along with the different types of validation/verification, and the types of methods, and the level of validation necessary depending on the degree of standardization. The situations in which validation/verification is mandatory and/or recommended is discussed, including those particularly related to validation in Microbiology. It stresses the importance of promoting the use of reference strains as controls in Microbiology and the use of standard controls, as well as the importance of participation in External Quality Assessment programs to demonstrate technical competence. The emphasis is on how to calculate some of the parameters required for validation/verification, such as the accuracy and precision. The development of these concepts can be found in the microbiological process SEIMC number 48: «Validation and verification of microbiological methods» www.seimc.org/protocols/microbiology. Copyright © 2013 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

Serial album validation for promotion of infant body weight control

PubMed Central

Saraiva, Nathalia Costa Gonzaga; Medeiros, Carla Campos Muniz; de Araujo, Thelma Leite

2018-01-01

ABSTRACT Objective: to validate the content and appearance of a serial album for children aged from 7 to 10 years addressing the topic of prevention and control of body weight. Method: methodological study with descriptive nature. The validation process was attended by 33 specialists in educational technologies and/or in excess of infantile weight. The agreement index of 80% was the minimum considered to guarantee the validation of the material. Results: most of the specialists had a doctoral degree and a graduate degree in nursing. Regarding content, illustrations, layout and relevance, all items were validated and 69.7% of the experts considered the album as great. The overall agreement validation index for the educational technology was 0.88. Only the script-sheet 3 did not reach the cutoff point of the content validation index. Changes were made to the material, such as title change, inclusion of the school context and insertion of nutritionist and physical educator in the story narrated in the album. Conclusion: the proposed serial album was considered valid by experts regarding content and appearance, suggesting that this technology has the potential to contribute in health education by promoting healthy weight in the age group of 7 to 10 years. PMID:29791665

75 FR 33632 - Renewal of Approved Information Collection, OMB Control Number 1004-0179

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-14

... Approved Information Collection, OMB Control Number 1004-0179 AGENCY: Bureau of Land Management, Interior.... This information collection activity was previously approved by the OMB, and assigned control number...: Title: Helium Contracts (43 CFR part 3195). OMB Control Number: 1004-0179. Summary: This collection of...

The Space Technology-7 Disturbance Reduction System Precision Control Flight Validation Experiment Control System Design

NASA Technical Reports Server (NTRS)

O'Donnell, James R.; Hsu, Oscar C.; Maghami, Peirman G.; Markley, F. Landis

2006-01-01

As originally proposed, the Space Technology-7 Disturbance Reduction System (DRS) project, managed out of the Jet Propulsion Laboratory, was designed to validate technologies required for future missions such as the Laser Interferometer Space Antenna (LISA). The two technologies to be demonstrated by DRS were Gravitational Reference Sensors (GRSs) and Colloidal MicroNewton Thrusters (CMNTs). Control algorithms being designed by the Dynamic Control System (DCS) team at the Goddard Space Flight Center would control the spacecraft so that it flew about a freely-floating GRS test mass, keeping it centered within its housing. For programmatic reasons, the GRSs were descoped from DRS. The primary goals of the new mission are to validate the performance of the CMNTs and to demonstrate precise spacecraft position control. DRS will fly as a part of the European Space Agency (ESA) LISA Pathfinder (LPF) spacecraft along with a similar ESA experiment, the LISA Technology Package (LTP). With no GRS, the DCS attitude and drag-free control systems make use of the sensor being developed by ESA as a part of the LTP. The control system is designed to maintain the spacecraft s position with respect to the test mass, to within 10 nm/the square root of Hz over the DRS science frequency band of 1 to 30 mHz.

High Reynolds Number Effects on HSCT Stability and Control Characteristics

NASA Technical Reports Server (NTRS)

Elzey, Michael B.; Owens, Lewis R., Jr.; Wahls, Richard A.; Wilson, Douglas L.

1999-01-01

Two wind tunnel tests during 1995 in the National Transonic Facility (NTF 070 and 073) served to define Reynolds number effects on longitudinal and lateral-directional stability and control. Testing was completed at both high lift and transonic conditions. The effect of Reynolds number on the total airplane configuration, horizontal and vertical tail effectiveness, forebody chine performance, rudder control and model aeroelastics was investigated. This paper will present pertinent stability and control results from these two test entries. Note that while model aeroelastic effects are examined in this presentation, no corrections for these effects have been made to the data.

Factor structure and validation of the Attentional Control Scale.

PubMed

Judah, Matt R; Grant, DeMond M; Mills, Adam C; Lechner, William V

2014-04-01

The Attentional Control Scale (ACS; Derryberry & Reed, 2002) has been used to assess executive control over attention in numerous studies, but no published data have examined the factor structure of the English version. The current studies addressed this need and tested the predictive and convergent validity of the ACS subscales. In Study 1, exploratory factor analysis yielded a two-factor model with Focusing and Shifting subscales. In Study 2, confirmatory factor analysis supported this model and suggested superior fit compared to the factor structure of the Icelandic version (Ólafsson et al., 2011). Study 3 examined correlations between the ACS subscales and measures of working memory, anxiety, and cognitive control. Study 4 examined correlations between the subscales and reaction times on a mixed-antisaccade task, revealing positive correlations for antisaccade performance and prosaccade latency with Focusing scores and between switch trial performance and Shifting scores. Additionally, the findings partially supported unique relationships between Focusing and trait anxiety and between Shifting and depression that have been noted in recent research. Although the results generally support the validity of the ACS, additional research using performance-based tasks is needed.

STR-validator: an open source platform for validation and process control.

PubMed

Hansson, Oskar; Gill, Peter; Egeland, Thore

2014-11-01

This paper addresses two problems faced when short tandem repeat (STR) systems are validated for forensic purposes: (1) validation is extremely time consuming and expensive, and (2) there is strong consensus about what to validate but not how. The first problem is solved by powerful data processing functions to automate calculations. Utilising an easy-to-use graphical user interface, strvalidator (hereafter referred to as STR-validator) can greatly increase the speed of validation. The second problem is exemplified by a series of analyses, and subsequent comparison with published material, highlighting the need for a common validation platform. If adopted by the forensic community STR-validator has the potential to standardise the analysis of validation data. This would not only facilitate information exchange but also increase the pace at which laboratories are able to switch to new technology. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

The validation by measurement theory of proposed object-oriented software metrics

NASA Technical Reports Server (NTRS)

Neal, Ralph D.

1994-01-01

Moving software development into the engineering arena requires controllability, and to control a process, it must be measurable. Measuring the process does no good if the product is not also measured, i.e., being the best at producing an inferior product does not define a quality process. Also, not every number extracted from software development is a valid measurement. A valid measurement only results when we are able to verify that the number is representative of the attribute that we wish to measure. Many proposed software metrics are used by practitioners without these metrics ever having been validated, leading to costly but often useless calculations. Several researchers have bemoaned the lack of scientific precision in much of the published software measurement work and have called for validation of software metrics by measurement theory. This dissertation applies measurement theory to validate fifty proposed object-oriented software metrics (Li and Henry, 1993; Chidamber and Kemerrer, 1994; Lorenz and Kidd, 1994).

21 CFR 201.18 - Drugs; significance of control numbers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Drugs; significance of control numbers. 201.18 Section 201.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.18 Drugs; significance of control...

21 CFR 201.18 - Drugs; significance of control numbers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Drugs; significance of control numbers. 201.18 Section 201.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.18 Drugs; significance of control...

21 CFR 201.18 - Drugs; significance of control numbers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Drugs; significance of control numbers. 201.18 Section 201.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.18 Drugs; significance of control...

21 CFR 201.18 - Drugs; significance of control numbers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Drugs; significance of control numbers. 201.18 Section 201.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.18 Drugs; significance of control...

21 CFR 201.18 - Drugs; significance of control numbers.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Drugs; significance of control numbers. 201.18 Section 201.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.18 Drugs; significance of control...

2-D Circulation Control Airfoil Benchmark Experiments Intended for CFD Code Validation

NASA Technical Reports Server (NTRS)

Englar, Robert J.; Jones, Gregory S.; Allan, Brian G.; Lin, Johb C.

2009-01-01

A current NASA Research Announcement (NRA) project being conducted by Georgia Tech Research Institute (GTRI) personnel and NASA collaborators includes the development of Circulation Control (CC) blown airfoils to improve subsonic aircraft high-lift and cruise performance. The emphasis of this program is the development of CC active flow control concepts for both high-lift augmentation, drag control, and cruise efficiency. A collaboration in this project includes work by NASA research engineers, whereas CFD validation and flow physics experimental research are part of NASA s systematic approach to developing design and optimization tools for CC applications to fixed-wing aircraft. The design space for CESTOL type aircraft is focusing on geometries that depend on advanced flow control technologies that include Circulation Control aerodynamics. The ability to consistently predict advanced aircraft performance requires improvements in design tools to include these advanced concepts. Validation of these tools will be based on experimental methods applied to complex flows that go beyond conventional aircraft modeling techniques. This paper focuses on recent/ongoing benchmark high-lift experiments and CFD efforts intended to provide 2-D CFD validation data sets related to NASA s Cruise Efficient Short Take Off and Landing (CESTOL) study. Both the experimental data and related CFD predictions are discussed.

44 CFR 2.2 - OMB control numbers assigned to information collections.

Code of Federal Regulations, 2012 CFR

2012-10-01

... to information collections. 2.2 Section 2.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY GENERAL OMB CONTROL NUMBERS § 2.2 OMB control numbers....202(f)(2), 206.203(c), 206.203(d)(i), 206.204(f) 1660-0017 206 subpart K 1660-0082, 1660-0083 206...

44 CFR 2.2 - OMB control numbers assigned to information collections.

Code of Federal Regulations, 2010 CFR

2010-10-01

... to information collections. 2.2 Section 2.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY GENERAL OMB CONTROL NUMBERS § 2.2 OMB control numbers....202(f)(2), 206.203(c), 206.203(d)(i), 206.204(f) 1660-0017 206 subpart K 1660-0082, 1660-0083 206...

44 CFR 2.2 - OMB control numbers assigned to information collections.

Code of Federal Regulations, 2014 CFR

2014-10-01

... to information collections. 2.2 Section 2.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY GENERAL OMB CONTROL NUMBERS § 2.2 OMB control numbers....202(f)(2), 206.203(c), 206.203(d)(i), 206.204(f) 1660-0017 206 subpart K 1660-0082, 1660-0083 206...

44 CFR 2.2 - OMB control numbers assigned to information collections.

Code of Federal Regulations, 2011 CFR

2011-10-01

... to information collections. 2.2 Section 2.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY GENERAL OMB CONTROL NUMBERS § 2.2 OMB control numbers....202(f)(2), 206.203(c), 206.203(d)(i), 206.204(f) 1660-0017 206 subpart K 1660-0082, 1660-0083 206...

44 CFR 2.2 - OMB control numbers assigned to information collections.

Code of Federal Regulations, 2013 CFR

2013-10-01

... to information collections. 2.2 Section 2.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY GENERAL OMB CONTROL NUMBERS § 2.2 OMB control numbers....202(f)(2), 206.203(c), 206.203(d)(i), 206.204(f) 1660-0017 206 subpart K 1660-0082, 1660-0083 206...

Design and control of compliant tensegrity robots through simulation and hardware validation

PubMed Central

Caluwaerts, Ken; Despraz, Jérémie; Işçen, Atıl; Sabelhaus, Andrew P.; Bruce, Jonathan; Schrauwen, Benjamin; SunSpiral, Vytas

2014-01-01

To better understand the role of tensegrity structures in biological systems and their application to robotics, the Dynamic Tensegrity Robotics Lab at NASA Ames Research Center, Moffett Field, CA, USA, has developed and validated two software environments for the analysis, simulation and design of tensegrity robots. These tools, along with new control methodologies and the modular hardware components developed to validate them, are presented as a system for the design of actuated tensegrity structures. As evidenced from their appearance in many biological systems, tensegrity (‘tensile–integrity’) structures have unique physical properties that make them ideal for interaction with uncertain environments. Yet, these characteristics make design and control of bioinspired tensegrity robots extremely challenging. This work presents the progress our tools have made in tackling the design and control challenges of spherical tensegrity structures. We focus on this shape since it lends itself to rolling locomotion. The results of our analyses include multiple novel control approaches for mobility and terrain interaction of spherical tensegrity structures that have been tested in simulation. A hardware prototype of a spherical six-bar tensegrity, the Reservoir Compliant Tensegrity Robot, is used to empirically validate the accuracy of simulation. PMID:24990292

Design and Control of Compliant Tensegrity Robots Through Simulation and Hardware Validation

NASA Technical Reports Server (NTRS)

Caluwaerts, Ken; Despraz, Jeremie; Iscen, Atil; Sabelhaus, Andrew P.; Bruce, Jonathan; Schrauwen, Benjamin; Sunspiral, Vytas

2014-01-01

To better understand the role of tensegrity structures in biological systems and their application to robotics, the Dynamic Tensegrity Robotics Lab at NASA Ames Research Center has developed and validated two different software environments for the analysis, simulation, and design of tensegrity robots. These tools, along with new control methodologies and the modular hardware components developed to validate them, are presented as a system for the design of actuated tensegrity structures. As evidenced from their appearance in many biological systems, tensegrity ("tensile-integrity") structures have unique physical properties which make them ideal for interaction with uncertain environments. Yet these characteristics, such as variable structural compliance, and global multi-path load distribution through the tension network, make design and control of bio-inspired tensegrity robots extremely challenging. This work presents the progress in using these two tools in tackling the design and control challenges. The results of this analysis includes multiple novel control approaches for mobility and terrain interaction of spherical tensegrity structures. The current hardware prototype of a six-bar tensegrity, code-named ReCTeR, is presented in the context of this validation.

Development and validation of measures to assess prevention and control of AMR in hospitals.

PubMed

Flanagan, Mindy; Ramanujam, Rangaraj; Sutherland, Jason; Vaughn, Thomas; Diekema, Daniel; Doebbeling, Bradley N

2007-06-01

The rapid spread of antimicrobial resistance (AMR) in the US hospitals poses serious quality and safety problems. Expert panels, identifying strategies for optimizing antibiotic use and preventing AMR spread, have recommended hospitals undertake efforts to implement specific evidence-based practices. To develop and validate a measurement scale for assessing hospitals' efforts to implement recommended AMR prevention and control measures. Surveys were mailed to infection control professionals in a national sample of 670 US hospitals stratified by geographic region, bedsize, teaching status, and VA affiliation. : Four hundred forty-eight infection control professionals participated (67% response rate). Survey items measured implementation of guideline recommendations, practices for AMR monitoring and feedback, AMR-related outcomes (methicillin-resistant Staphylococcus aureus prevalence and outbreaks [MRSA]), and organizational features. "Derivation" and "validation" samples were randomly selected. Exploratory factor analysis was performed to identify factors underlying AMR prevention and control efforts. Multiple methods were used for validation. We identified 4 empirically distinct factors in AMR prevention and control: (1) practices for antimicrobial prescription/use, (2) information/resources for AMR control, (3) practices for isolating infected patients, and (4) organizational support for infection control policies. The Prevention and Control of Antimicrobial Resistance scale was reliable and had content and construct validity. MRSA prevalence was significantly lower in hospitals with higher resource/information availability and broader organizational support. The Prevention and Control of Antimicrobial Resistance scale offers a simple yet discriminating assessment of AMR prevention and control efforts. Use should complement assessment methods based exclusively on AMR outcomes.

Flight-Test Validation and Flying Qualities Evaluation of a Rotorcraft UAV Flight Control System

NASA Technical Reports Server (NTRS)

Mettler, Bernard; Tuschler, Mark B.; Kanade, Takeo

2000-01-01

This paper presents a process of design and flight-test validation and flying qualities evaluation of a flight control system for a rotorcraft-based unmanned aerial vehicle (RUAV). The keystone of this process is an accurate flight-dynamic model of the aircraft, derived by using system identification modeling. The model captures the most relevant dynamic features of our unmanned rotorcraft, and explicitly accounts for the presence of a stabilizer bar. Using the identified model we were able to determine the performance margins of our original control system and identify limiting factors. The performance limitations were addressed and the attitude control system was 0ptimize.d for different three performance levels: slow, medium, fast. The optimized control laws will be implemented in our RUAV. We will first determine the validity of our control design approach by flight test validating our optimized controllers. Subsequently, we will fly a series of maneuvers with the three optimized controllers to determine the level of flying qualities that can be attained. The outcome enable us to draw important conclusions on the flying qualities requirements for small-scale RUAVs.

An empirical study of the predictive validity of number grades in medical school using 3 decades of longitudinal data: implications for a grading system.

PubMed

Gonnella, Joseph S; Erdmann, James B; Hojat, Mohammadreza

2004-04-01

Context It is important to establish the predictive validity of medical school grades. The strength of predictive validity and the ability to identify at-risk students in medical schools depends upon assessment systems such as number grades, pass/fail (P/F) or honours/pass/fail (H/P/F) systems. Objective This study was designed to examine the predictive validity of number grades in medical school, and to determine whether any important information is lost in a shift from number to P/F and H/P/F grading systems. Subjects The participants in this prospective, longitudinal study were 6656 medical students who studied at Jefferson Medical College over 3 decades. They were grouped into 10 deciles based on their number grades in Year 1 of medical school. Methods Participants were compared on academic accomplishments in Years 2 and 3 of medical school, medical school class rank, delayed graduation and attrition, performance on medical licensing examinations and clinical competence ratings in the first postgraduate year. Results Results supported the short- and longterm predictive validity of the number grades. Ratings of clinical competence beyond medical school were predicted by number grades in medical school. We demonstrated that small differences in number grades are statistically meaningful, and that important information for identifying students in need of remedial education is lost when students who narrowly meet faculty's expectations are included with the rest of the class in a broad 'pass' category. Conclusions The findings refute the argument that knowledge of sciences basic to medicine is not critical to subsequent performance in medical school and beyond if an appropriate evaluation system is used. Furthermore, the results of this study raise questions about abandoning number grades in favour of a pass/fail system. Consideration of these findings in policy decisions regarding assessment systems of medical students is recommended.

Validating a UAV artificial intelligence control system using an autonomous test case generator

NASA Astrophysics Data System (ADS)

Straub, Jeremy; Huber, Justin

2013-05-01

The validation of safety-critical applications, such as autonomous UAV operations in an environment which may include human actors, is an ill posed problem. To confidence in the autonomous control technology, numerous scenarios must be considered. This paper expands upon previous work, related to autonomous testing of robotic control algorithms in a two dimensional plane, to evaluate the suitability of similar techniques for validating artificial intelligence control in three dimensions, where a minimum level of airspeed must be maintained. The results of human-conducted testing are compared to this automated testing, in terms of error detection, speed and testing cost.

Structured Uncertainty Bound Determination From Data for Control and Performance Validation

NASA Technical Reports Server (NTRS)

Lim, Kyong B.

2003-01-01

This report attempts to document the broad scope of issues that must be satisfactorily resolved before one can expect to methodically obtain, with a reasonable confidence, a near-optimal robust closed loop performance in physical applications. These include elements of signal processing, noise identification, system identification, model validation, and uncertainty modeling. Based on a recently developed methodology involving a parameterization of all model validating uncertainty sets for a given linear fractional transformation (LFT) structure and noise allowance, a new software, Uncertainty Bound Identification (UBID) toolbox, which conveniently executes model validation tests and determine uncertainty bounds from data, has been designed and is currently available. This toolbox also serves to benchmark the current state-of-the-art in uncertainty bound determination and in turn facilitate benchmarking of robust control technology. To help clarify the methodology and use of the new software, two tutorial examples are provided. The first involves the uncertainty characterization of a flexible structure dynamics, and the second example involves a closed loop performance validation of a ducted fan based on an uncertainty bound from data. These examples, along with other simulation and experimental results, also help describe the many factors and assumptions that determine the degree of success in applying robust control theory to practical problems.

A Validated Method for the Quality Control of Andrographis paniculata Preparations.

PubMed

Karioti, Anastasia; Timoteo, Patricia; Bergonzi, Maria Camilla; Bilia, Anna Rita

2017-10-01

Andrographis paniculata is a herbal drug of Asian traditional medicine largely employed for the treatment of several diseases. Recently, it has been introduced in Europe for the prophylactic and symptomatic treatment of common cold and as an ingredient of dietary supplements. The active principles are diterpenes with andrographolide as the main representative. In the present study, an analytical protocol was developed for the determination of the main constituents in the herb and preparations of A. paniculata . Three different extraction protocols (methanol extraction using a modified Soxhlet procedure, maceration under ultrasonication, and decoction) were tested. Ultrasonication achieved the highest content of analytes. HPLC conditions were optimized in terms of solvent mixtures, time course, and temperature. A reversed phase C18 column eluted with a gradient system consisting of acetonitrile and acidified water and including an isocratic step at 30 °C was used. The HPLC method was validated for linearity, limits of quantitation and detection, repeatability, precision, and accuracy. The overall method was validated for precision and accuracy over at least three different concentration levels. Relative standard deviation was less than 1.13%, whereas recovery was between 95.50% and 97.19%. The method also proved to be suitable for the determination of a large number of commercial samples and was proposed to the European Pharmacopoeia for the quality control of Andrographidis herba. Georg Thieme Verlag KG Stuttgart · New York.

Experimental Validation of an Integrated Controls-Structures Design Methodology

NASA Technical Reports Server (NTRS)

Maghami, Peiman G.; Gupta, Sandeep; Elliot, Kenny B.; Walz, Joseph E.

1996-01-01

The first experimental validation of an integrated controls-structures design methodology for a class of large order, flexible space structures is described. Integrated redesign of the controls-structures-interaction evolutionary model, a laboratory testbed at NASA Langley, was described earlier. The redesigned structure was fabricated, assembled in the laboratory, and experimentally tested against the original structure. Experimental results indicate that the structure redesigned using the integrated design methodology requires significantly less average control power than the nominal structure with control-optimized designs, while maintaining the required line-of-sight pointing performance. Thus, the superiority of the integrated design methodology over the conventional design approach is experimentally demonstrated. Furthermore, amenability of the integrated design structure to other control strategies is evaluated, both analytically and experimentally. Using Linear-Quadratic-Guassian optimal dissipative controllers, it is observed that the redesigned structure leads to significantly improved performance with alternate controllers as well.

Performance validation of the ANSER control laws for the F-18 HARV

NASA Technical Reports Server (NTRS)

Messina, Michael D.

1995-01-01

The ANSER control laws were implemented in Ada by NASA Dryden for flight test on the High Alpha Research Vehicle (HARV). The Ada implementation was tested in the hardware-in-the-loop (HIL) simulation, and results were compared to those obtained with the NASA Langley batch Fortran implementation of the control laws which are considered the 'truth model.' This report documents the performance validation test results between these implementations. This report contains the ANSER performance validation test plan, HIL versus batch time-history comparisons, simulation scripts used to generate checkcases, and detailed analysis of discrepancies discovered during testing.

Performance validation of the ANSER Control Laws for the F-18 HARV

NASA Technical Reports Server (NTRS)

Messina, Michael D.

1995-01-01

The ANSER control laws were implemented in Ada by NASA Dryden for flight test on the High Alpha Research Vehicle (HARV). The Ada implementation was tested in the hardware-in-the-loop (HIL) simulation, and results were compared to those obtained with the NASA Langley batch Fortran implementation of the control laws which are considered the 'truth model'. This report documents the performance validation test results between these implementations. This report contains the ANSER performance validation test plan, HIL versus batch time-history comparisons, simulation scripts used to generate checkcases, and detailed analysis of discrepancies discovered during testing.

Design and control of compliant tensegrity robots through simulation and hardware validation.

PubMed

Caluwaerts, Ken; Despraz, Jérémie; Işçen, Atıl; Sabelhaus, Andrew P; Bruce, Jonathan; Schrauwen, Benjamin; SunSpiral, Vytas

2014-09-06

To better understand the role of tensegrity structures in biological systems and their application to robotics, the Dynamic Tensegrity Robotics Lab at NASA Ames Research Center, Moffett Field, CA, USA, has developed and validated two software environments for the analysis, simulation and design of tensegrity robots. These tools, along with new control methodologies and the modular hardware components developed to validate them, are presented as a system for the design of actuated tensegrity structures. As evidenced from their appearance in many biological systems, tensegrity ('tensile-integrity') structures have unique physical properties that make them ideal for interaction with uncertain environments. Yet, these characteristics make design and control of bioinspired tensegrity robots extremely challenging. This work presents the progress our tools have made in tackling the design and control challenges of spherical tensegrity structures. We focus on this shape since it lends itself to rolling locomotion. The results of our analyses include multiple novel control approaches for mobility and terrain interaction of spherical tensegrity structures that have been tested in simulation. A hardware prototype of a spherical six-bar tensegrity, the Reservoir Compliant Tensegrity Robot, is used to empirically validate the accuracy of simulation. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

Validation of Biomarkers of the Tumor Microenvironment

DTIC Science & Technology

2014-10-01

A ., Yao, H., Rahmatpanah, F., Xia, X. Q., Xu, Q., Pio, R., Turan , T., Koziol, J. A ., Goodison, S., Carpenter, P., Wang-Rodriguez, J., Simoneau, A ...to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE...embedded) prostate cancer biopsy tissue in order validate the accuracy of a stroma-based classifier for diagnosis of prostate cancer using FFPE

Cigar Box Arthroscopy: A Randomized Controlled Trial Validates Nonanatomic Simulation Training of Novice Arthroscopy Skills.

PubMed

Sandberg, Rory P; Sherman, Nathan C; Latt, L Daniel; Hardy, Jolene C

2017-11-01

The goal of this study was to validate the cigar box arthroscopy trainer (CBAT) as a training tool and then compare its effectiveness to didactic training and to another previously validated low-fidelity but anatomic model, the anatomic knee arthroscopy trainer (AKAT). A nonanatomic knee arthroscopy training module was developed at our institution. Twenty-four medical students with no prior arthroscopic or laparoscopic experience were enrolled as subjects. Eight subjects served as controls. The remaining 16 subjects were randomized to participate in 4 hours of either the CBAT or a previously validated AKAT. Subjects' skills were assessed by 1 of 2 faculty members through repeated attempts at performing a diagnostic knee arthroscopy on a cadaveric specimen. Objective scores were given using a minimally adapted version of the Basic Arthroscopic Knee Skill Scoring System. Total cost differences were calculated. Seventy-five percent of subjects in the CBAT and AKAT groups succeeded in reaching minimum proficiency in the allotted time compared with 25% in the control group (P < .05). There was no significant difference in the number of attempts to reach proficiency between the CBAT and AKAT groups. The cost to build the CBAT was $44.12, whereas the cost was $324.33 for the AKAT. This pilot study suggests the CBAT is an effective knee arthroscopy trainer that may decrease the learning curve of residents without significant cost to a residency program. This study demonstrates the need for an agreed-upon objective scoring system to properly evaluate residents and compare the effectiveness of different training tools. Copyright © 2017 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

46 CFR 502.991 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROVISIONS RULES OF PRACTICE AND PROCEDURE Paperwork Reduction Act § 502.991 OMB control numbers assigned pursuant to the Paperwork Reduction Act. This section displays the control numbers assigned to information... comply with the Act, which requires that agencies display a current control number assigned by the...

29 CFR 1910.8 - OMB control numbers under the Paperwork Reduction Act.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 5 2012-07-01 2012-07-01 false OMB control numbers under the Paperwork Reduction Act. 1910.8 Section 1910.8 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR OCCUPATIONAL SAFETY AND HEALTH STANDARDS General § 1910.8 OMB control numbers...

29 CFR 1910.8 - OMB control numbers under the Paperwork Reduction Act.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 5 2011-07-01 2011-07-01 false OMB control numbers under the Paperwork Reduction Act. 1910.8 Section 1910.8 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR OCCUPATIONAL SAFETY AND HEALTH STANDARDS General § 1910.8 OMB control numbers...

75 FR 7548 - Amendments to the Select Agents Controls in Export Control Classification Number (ECCN) 1C360 on...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-22

...-91434-01] RIN 0694-AE67 Amendments to the Select Agents Controls in Export Control Classification Number... controls on certain select agents identified in Export Control Classification Number (ECCN) 1C360 on the...) list of select agents and toxins. The changes made by APHIS were part of a biennial review and...

7 CFR 1940.350 - Office of Management and Budget (OMB) control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Office of Management and Budget (OMB) control number....350 Office of Management and Budget (OMB) control number. The collection of information requirements in this regulation has been approved by the Office of Management and Budget and has been assigned OMB...

Proposal and validation of a clinical trunk control test in individuals with spinal cord injury.

PubMed

Quinzaños, J; Villa, A R; Flores, A A; Pérez, R

2014-06-01

One of the problems that arise in spinal cord injury (SCI) is alteration in trunk control. Despite the need for standardized scales, these do not exist for evaluating trunk control in SCI. To propose and validate a trunk control test in individuals with SCI. National Institute of Rehabilitation, Mexico. The test was developed and later evaluated for reliability and criteria, content, and construct validity. We carried out 531 tests on 177 patients and found high inter- and intra-rater reliability. In terms of criterion validity, analysis of variance demonstrated a statistically significant difference in the test score of patients with adequate or inadequate trunk control according to the assessment of a group of experts. A receiver operating characteristic curve was plotted for optimizing the instrument's cutoff point, which was determined at 13 points, with a sensitivity of 98% and a specificity of 92.2%. With regard to construct validity, the correlation between the proposed test and the spinal cord independence measure (SCIM) was 0.873 (P=0.001) and that with the evolution time was 0.437 (P=0.001). For testing the hypothesis with qualitative variables, the Kruskal-Wallis test was performed, which resulted in a statistically significant difference between the scores in the proposed scale of each group defined by these variables. It was proven experimentally that the proposed trunk control test is valid and reliable. Furthermore, the test can be used for all patients with SCI despite the type and level of injury.

Androstenedione response to recombinant human FSH is the most valid predictor of the number of selected follicles in polycystic ovarian syndrome: (a case-control study).

PubMed

Ozyurek, Eser Sefik; Yoldemir, Tevfik; Artar, Gokhan

2017-05-12

We aimed to test the hypothesis that the correlation of the changes in the blood Androstenedione (A 4 ) levels to the number of selected follicles during ovulation induction with low-dose recombinant human follicle stimulating hormone (rhFSH) is as strong as the correlation to changes in the blood Estradiol (E 2 ) levels in polycystic ovary syndrome (PCOS). Prospective Case-control study conducted from October 2014 to January 2016. 61 non-PCOS control (Group I) and 46 PCOS (Group II) patients treated with the chronic low-dose step up protocosl with rhFSH. A 4 , E 2 , progesterone blood levels and follicular growth were monitored.. Univariate and hierarchical multivariable analysis were performed for age, BMI, HOMA-IR, A 4 and E 2 (with the number of selected follicles as the dependent variable in both groups). ROC analysis was performed to define threshold values for the significant determinants of the number of selected follicles to predict cyle cancellations due to excessive ovarian response. The control group (Group I) was comprised of 61 cycles from a group of primary infertile non-PCOS patients, and the study group (Group II) of 46 cycles of PCOS patients. The analysis revealed that the strongest independent predictor of the total number of selected follicles in Group I was the E 2 (AUC) (B = 0.0006[0.0003-0.001]; P < 0.001); whereas for Group II, it was the A 4 (AUC) (B = 0.114[0.04-0.25]; P = 0.01). Optimum thresholds for the A 4 related parameters were defined to predict excessive response within Group II were 88.7%, 3.1 ng/mL and 5.4 ng*days for the percentage increase in A 4 , the maximum A 4 value and area under the curve values for A 4 , respectively. A 4 response to low-dose rhFSH in PCOS has a stronger association with the number of follicles selected than the E 2 reponse. A 4 response preceding the E 2 response is essential for progressive follicle development. Monitoring A 4 rather than E 2 may be more preemptive to define the initial

Modeling validation and control analysis for controlled temperature and humidity of air conditioning system.

PubMed

Lee, Jing-Nang; Lin, Tsung-Min; Chen, Chien-Chih

2014-01-01

This study constructs an energy based model of thermal system for controlled temperature and humidity air conditioning system, and introduces the influence of the mass flow rate, heater and humidifier for proposed control criteria to achieve the controlled temperature and humidity of air conditioning system. Then, the reliability of proposed thermal system model is established by both MATLAB dynamic simulation and the literature validation. Finally, the PID control strategy is applied for controlling the air mass flow rate, humidifying capacity, and heating, capacity. The simulation results show that the temperature and humidity are stable at 541 sec, the disturbance of temperature is only 0.14 °C, 0006 kg(w)/kg(da) in steady-state error of humidity ratio, and the error rate is only 7.5%. The results prove that the proposed system is an effective controlled temperature and humidity of an air conditioning system.

Modeling Validation and Control Analysis for Controlled Temperature and Humidity of Air Conditioning System

PubMed Central

Lee, Jing-Nang; Lin, Tsung-Min

2014-01-01

This study constructs an energy based model of thermal system for controlled temperature and humidity air conditioning system, and introduces the influence of the mass flow rate, heater and humidifier for proposed control criteria to achieve the controlled temperature and humidity of air conditioning system. Then, the reliability of proposed thermal system model is established by both MATLAB dynamic simulation and the literature validation. Finally, the PID control strategy is applied for controlling the air mass flow rate, humidifying capacity, and heating, capacity. The simulation results show that the temperature and humidity are stable at 541 sec, the disturbance of temperature is only 0.14°C, 0006 kgw/kgda in steady-state error of humidity ratio, and the error rate is only 7.5%. The results prove that the proposed system is an effective controlled temperature and humidity of an air conditioning system. PMID:25250390

Validity of clinical color vision tests for air traffic control specialists.

DOT National Transportation Integrated Search

1992-10-01

An experiment on the relationship between aeromedical color vision screening test performance and performance on color-dependent tasks of Air Traffic Control Specialists was replicated to expand the data base supporting the job-related validity of th...

Risk-based Methodology for Validation of Pharmaceutical Batch Processes.

PubMed

Wiles, Frederick

2013-01-01

In January 2011, the U.S. Food and Drug Administration published new process validation guidance for pharmaceutical processes. The new guidance debunks the long-held industry notion that three consecutive validation batches or runs are all that are required to demonstrate that a process is operating in a validated state. Instead, the new guidance now emphasizes that the level of monitoring and testing performed during process performance qualification (PPQ) studies must be sufficient to demonstrate statistical confidence both within and between batches. In some cases, three qualification runs may not be enough. Nearly two years after the guidance was first published, little has been written defining a statistical methodology for determining the number of samples and qualification runs required to satisfy Stage 2 requirements of the new guidance. This article proposes using a combination of risk assessment, control charting, and capability statistics to define the monitoring and testing scheme required to show that a pharmaceutical batch process is operating in a validated state. In this methodology, an assessment of process risk is performed through application of a process failure mode, effects, and criticality analysis (PFMECA). The output of PFMECA is used to select appropriate levels of statistical confidence and coverage which, in turn, are used in capability calculations to determine when significant Stage 2 (PPQ) milestones have been met. The achievement of Stage 2 milestones signals the release of batches for commercial distribution and the reduction of monitoring and testing to commercial production levels. Individuals, moving range, and range/sigma charts are used in conjunction with capability statistics to demonstrate that the commercial process is operating in a state of statistical control. The new process validation guidance published by the U.S. Food and Drug Administration in January of 2011 indicates that the number of process validation batches

Validation of Safety-Critical Systems for Aircraft Loss-of-Control Prevention and Recovery

NASA Technical Reports Server (NTRS)

Belcastro, Christine M.

2012-01-01

Validation of technologies developed for loss of control (LOC) prevention and recovery poses significant challenges. Aircraft LOC can result from a wide spectrum of hazards, often occurring in combination, which cannot be fully replicated during evaluation. Technologies developed for LOC prevention and recovery must therefore be effective under a wide variety of hazardous and uncertain conditions, and the validation framework must provide some measure of assurance that the new vehicle safety technologies do no harm (i.e., that they themselves do not introduce new safety risks). This paper summarizes a proposed validation framework for safety-critical systems, provides an overview of validation methods and tools developed by NASA to date within the Vehicle Systems Safety Project, and develops a preliminary set of test scenarios for the validation of technologies for LOC prevention and recovery

Experimental validation of flexible robot arm modeling and control

NASA Technical Reports Server (NTRS)

Ulsoy, A. Galip

1989-01-01

Flexibility is important for high speed, high precision operation of lightweight manipulators. Accurate dynamic modeling of flexible robot arms is needed. Previous work has mostly been based on linear elasticity with prescribed rigid body motions (i.e., no effect of flexible motion on rigid body motion). Little or no experimental validation of dynamic models for flexible arms is available. Experimental results are also limited for flexible arm control. Researchers include the effects of prismatic as well as revolute joints. They investigate the effect of full coupling between the rigid and flexible motions, and of axial shortening, and consider the control of flexible arms using only additional sensors.

Quality control and assurance for validation of DOS/I measurements

NASA Astrophysics Data System (ADS)

Cerussi, Albert; Durkin, Amanda; Kwong, Richard; Quang, Timothy; Hill, Brian; Tromberg, Bruce J.; MacKinnon, Nick; Mantulin, William W.

2010-02-01

Ongoing multi-center clinical trials are crucial for Biophotonics to gain acceptance in medical imaging. In these trials, quality control (QC) and assurance (QA) are key to success and provide "data insurance". Quality control and assurance deal with standardization, validation, and compliance of procedures, materials and instrumentation. Specifically, QC/QA involves systematic assessment of testing materials, instrumentation performance, standard operating procedures, data logging, analysis, and reporting. QC and QA are important for FDA accreditation and acceptance by the clinical community. Our Biophotonics research in the Network for Translational Research in Optical Imaging (NTROI) program for breast cancer characterization focuses on QA/QC issues primarily related to the broadband Diffuse Optical Spectroscopy and Imaging (DOS/I) instrumentation, because this is an emerging technology with limited standardized QC/QA in place. In the multi-center trial environment, we implement QA/QC procedures: 1. Standardize and validate calibration standards and procedures. (DOS/I technology requires both frequency domain and spectral calibration procedures using tissue simulating phantoms and reflectance standards, respectively.) 2. Standardize and validate data acquisition, processing and visualization (optimize instrument software-EZDOS; centralize data processing) 3. Monitor, catalog and maintain instrument performance (document performance; modularize maintenance; integrate new technology) 4. Standardize and coordinate trial data entry (from individual sites) into centralized database 5. Monitor, audit and communicate all research procedures (database, teleconferences, training sessions) between participants ensuring "calibration". This manuscript describes our ongoing efforts, successes and challenges implementing these strategies.

Assessing validity of observational intervention studies - the Benchmarking Controlled Trials.

PubMed

Malmivaara, Antti

2016-09-01

Benchmarking Controlled Trial (BCT) is a concept which covers all observational studies aiming to assess impact of interventions or health care system features to patients and populations. To create and pilot test a checklist for appraising methodological validity of a BCT. The checklist was created by extracting the most essential elements from the comprehensive set of criteria in the previous paper on BCTs. Also checklists and scientific papers on observational studies and respective systematic reviews were utilized. Ten BCTs published in the Lancet and in the New England Journal of Medicine were used to assess feasibility of the created checklist. The appraised studies seem to have several methodological limitations, some of which could be avoided in planning, conducting and reporting phases of the studies. The checklist can be used for planning, conducting, reporting, reviewing, and critical reading of observational intervention studies. However, the piloted checklist should be validated in further studies. Key messages Benchmarking Controlled Trial (BCT) is a concept which covers all observational studies aiming to assess impact of interventions or health care system features to patients and populations. This paper presents a checklist for appraising methodological validity of BCTs and pilot-tests the checklist with ten BCTs published in leading medical journals. The appraised studies seem to have several methodological limitations, some of which could be avoided in planning, conducting and reporting phases of the studies. The checklist can be used for planning, conducting, reporting, reviewing, and critical reading of observational intervention studies.

New validated recipes for double-blind placebo-controlled low-dose food challenges.

PubMed

Winberg, Anna; Nordström, Lisbeth; Strinnholm, Åsa; Nylander, Annica; Jonsäll, Anette; Rönmark, Eva; West, Christina E

2013-05-01

Double-blind placebo-controlled food challenges are considered the most reliable method to diagnose or rule out food allergy. Despite this, there are few validated challenge recipes available. The present study aimed to validate new recipes for low-dose double-blind placebo-controlled food challenges in school children, by investigating whether there were any sensory differences between the active materials containing cow's milk, hen's egg, soy, wheat or cod, and the placebo materials. The challenge materials contained the same hypoallergenic amino acid-based product, with or without added food allergens. The test panels consisted of 275 school children, aged 8-10 and 14-15 yr, respectively, from five Swedish schools. Each participant tested at least one recipe. Standardized blinded triangle tests were performed to investigate whether any sensory differences could be detected between the active and placebo materials. In our final recipes, no significant differences could be detected between the active and placebo materials for any challenge food (p > 0.05). These results remained after stratification for age and gender. The taste of challenge materials was acceptable, and no unfavourable side effects related to test materials were observed. In summary, these new validated recipes for low-dose double-blinded food challenges contain common allergenic foods in childhood; cow's milk, hen's egg, soy, wheat and cod. All test materials contain the same liquid vehicle, which facilitates preparation and dosing. Our validated recipes increase the range of available recipes, and as they are easily prepared and dosed, they may facilitate the use of double-blind placebo-controlled food challenges in daily clinical practice. © 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.

4TH Marine Division Operation Plan Number 49-44

DTIC Science & Technology

1944-12-26

information if it does not display a currently valid OMB control number. 1. REPORT DATE MAY 1972 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND...assigned (Annex DOG to Adm 0 No. ;44-44,. (2) 4th Tk Bn (less Cos A, B, & C), on landing, be prepared to assume control of Tk Elms as released and Spt...the Atk. (3) 41th Ned Bn, on landing Bn Ho and on Div order, assume control of Cos A, B, and C ashore, prepared to land the remainder of the Bn on Div

76 FR 7629 - Interagency Notice of Change in Control

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-10

... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Interagency Notice of Change in Control... information collection displays a currently valid OMB control number. As part of the approval process, we... in Control. OMB Number: 1550-0032. Form Number: 1622. Description: The Regional Office must review...

Effective normalization for copy number variation detection from whole genome sequencing.

PubMed

Janevski, Angel; Varadan, Vinay; Kamalakaran, Sitharthan; Banerjee, Nilanjana; Dimitrova, Nevenka

2012-01-01

Whole genome sequencing enables a high resolution view of the human genome and provides unique insights into genome structure at an unprecedented scale. There have been a number of tools to infer copy number variation in the genome. These tools, while validated, also include a number of parameters that are configurable to genome data being analyzed. These algorithms allow for normalization to account for individual and population-specific effects on individual genome CNV estimates but the impact of these changes on the estimated CNVs is not well characterized. We evaluate in detail the effect of normalization methodologies in two CNV algorithms FREEC and CNV-seq using whole genome sequencing data from 8 individuals spanning four populations. We apply FREEC and CNV-seq to a sequencing data set consisting of 8 genomes. We use multiple configurations corresponding to different read-count normalization methodologies in FREEC, and statistically characterize the concordance of the CNV calls between FREEC configurations and the analogous output from CNV-seq. The normalization methodologies evaluated in FREEC are: GC content, mappability and control genome. We further stratify the concordance analysis within genic, non-genic, and a collection of validated variant regions. The GC content normalization methodology generates the highest number of altered copy number regions. Both mappability and control genome normalization reduce the total number and length of copy number regions. Mappability normalization yields Jaccard indices in the 0.07 - 0.3 range, whereas using a control genome normalization yields Jaccard index values around 0.4 with normalization based on GC content. The most critical impact of using mappability as a normalization factor is substantial reduction of deletion CNV calls. The output of another method based on control genome normalization, CNV-seq, resulted in comparable CNV call profiles, and substantial agreement in variable gene and CNV region calls

A study for active control research and validation using the Total In-Flight Simulator (TIFS) aircraft

NASA Technical Reports Server (NTRS)

Chen, R. T. N.; Daughaday, H.; Andrisani, D., II; Till, R. D.; Weingarten, N. C.

1975-01-01

The results of a feasibility study and preliminary design for active control research and validation using the Total In-Flight Simulator (TIFS) aircraft are documented. Active control functions which can be demonstrated on the TIFS aircraft and the cost of preparing, equipping, and operating the TIFS aircraft for active control technology development are determined. It is shown that the TIFS aircraft is as a suitable test bed for inflight research and validation of many ACT concepts.

46 CFR 565.13 - OMB control number assigned pursuant to the Paperwork Reduction Act

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 9 2010-10-01 2010-10-01 false OMB control number assigned pursuant to the Paperwork Reduction Act 565.13 Section 565.13 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AND ACTIONS TO ADDRESS RESTRICTIVE FOREIGN MARITIME PRACTICES CONTROLLED CARRIERS § 565.13 OMB control number assigned pursuant to...

Feedback control of flow vorticity at low Reynolds numbers.

PubMed

Zeitz, Maria; Gurevich, Pavel; Stark, Holger

2015-03-01

Our aim is to explore strategies of feedback control to design and stabilize novel dynamic flow patterns in model systems of complex fluids. To introduce the control strategies, we investigate the simple Newtonian fluid at low Reynolds number in a circular geometry. Then, the fluid vorticity satisfies a diffusion equation. We determine the mean vorticity in the sensing area and use two control strategies to feed it back into the system by controlling the angular velocity of the circular boundary. Hysteretic feedback control generates self-regulated stable oscillations in time, the frequency of which can be adjusted over several orders of magnitude by tuning the relevant feedback parameters. Time-delayed feedback control initiates unstable vorticity modes for sufficiently large feedback strength. For increasing delay time, we first observe oscillations with beats and then regular trains of narrow pulses. Close to the transition line between the resting fluid and the unstable modes, these patterns are relatively stable over long times.

Controller certification: The generalized stability margin inference for a large number of MIMO controllers

NASA Astrophysics Data System (ADS)

Park, Jisang

In this dissertation, we investigate MIMO stability margin inference of a large number of controllers using pre-established stability margins of a small number of nu-gap-wise adjacent controllers. The generalized stability margin and the nu-gap metric are inherently able to handle MIMO system analysis without the necessity of repeating multiple channel-by-channel SISO analyses. This research consists of three parts: (i) development of a decision support tool for inference of the stability margin, (ii) computational considerations for yielding the maximal stability margin with the minimal nu-gap metric in a less conservative manner, and (iii) experiment design for estimating the generalized stability margin with an assured error bound. A modern problem from aerospace control involves the certification of a large set of potential controllers with either a single plant or a fleet of potential plant systems, with both plants and controllers being MIMO and, for the moment, linear. Experiments on a limited number of controller/plant pairs should establish the stability and a certain level of margin of the complete set. We consider this certification problem for a set of controllers and provide algorithms for selecting an efficient subset for testing. This is done for a finite set of candidate controllers and, at least for SISO plants, for an infinite set. In doing this, the nu-gap metric will be the main tool. We provide a theorem restricting a radius of a ball in the parameter space so that the controller can guarantee a prescribed level of stability and performance if parameters of the controllers are contained in the ball. Computational examples are given, including one of certification of an aircraft engine controller. The overarching aim is to introduce truly MIMO margin calculations and to understand their efficacy in certifying stability over a set of controllers and in replacing legacy single-loop gain and phase margin calculations. We consider methods for the

Validation of Digital Systems in Avionics and Flight Control Applications Handbook. Volume 1.

DTIC Science & Technology

1983-07-01

will also be available to Airways Facilities, Systems Research and Development Service, Air Traffic Control Service, and Flight Standards elements...2114, March 12-14, 1979. 3. Validation Methods Research for Fault-Tolerant Avionics and Control Systems-- *r Working Group Meeting II, NASA...command generation with the multiple methods becoming avail- able for closure of the outer control loop necessitates research on alternative integration

Physics of lateral triple quantum-dot molecules with controlled electron numbers.

PubMed

Hsieh, Chang-Yu; Shim, Yun-Pil; Korkusinski, Marek; Hawrylak, Pawel

2012-11-01

We review the recent progress in theory and experiments with lateral triple quantum dots with controlled electron numbers down to one electron in each dot. The theory covers electronic and spin properties as a function of topology, number of electrons, gate voltage and external magnetic field. The orbital Hund's rules and Nagaoka ferromagnetism, magnetic frustration and chirality, interplay of quantum interference and electron-electron interactions and geometrical phases are described and related to charging and transport spectroscopy. Fabrication techniques and recent experiments are covered, as well as potential applications of triple quantum-dot molecule in coherent control, spin manipulation and quantum computation.

Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study

PubMed Central

Ross-Adams, H.; Lamb, A.D.; Dunning, M.J.; Halim, S.; Lindberg, J.; Massie, C.M.; Egevad, L.A.; Russell, R.; Ramos-Montoya, A.; Vowler, S.L.; Sharma, N.L.; Kay, J.; Whitaker, H.; Clark, J.; Hurst, R.; Gnanapragasam, V.J.; Shah, N.C.; Warren, A.Y.; Cooper, C.S.; Lynch, A.G.; Stark, R.; Mills, I.G.; Grönberg, H.; Neal, D.E.

2015-01-01

Background Understanding the heterogeneous genotypes and phenotypes of prostate cancer is fundamental to improving the way we treat this disease. As yet, there are no validated descriptions of prostate cancer subgroups derived from integrated genomics linked with clinical outcome. Methods In a study of 482 tumour, benign and germline samples from 259 men with primary prostate cancer, we used integrative analysis of copy number alterations (CNA) and array transcriptomics to identify genomic loci that affect expression levels of mRNA in an expression quantitative trait loci (eQTL) approach, to stratify patients into subgroups that we then associated with future clinical behaviour, and compared with either CNA or transcriptomics alone. Findings We identified five separate patient subgroups with distinct genomic alterations and expression profiles based on 100 discriminating genes in our separate discovery and validation sets of 125 and 103 men. These subgroups were able to consistently predict biochemical relapse (p = 0.0017 and p = 0.016 respectively) and were further validated in a third cohort with long-term follow-up (p = 0.027). We show the relative contributions of gene expression and copy number data on phenotype, and demonstrate the improved power gained from integrative analyses. We confirm alterations in six genes previously associated with prostate cancer (MAP3K7, MELK, RCBTB2, ELAC2, TPD52, ZBTB4), and also identify 94 genes not previously linked to prostate cancer progression that would not have been detected using either transcript or copy number data alone. We confirm a number of previously published molecular changes associated with high risk disease, including MYC amplification, and NKX3-1, RB1 and PTEN deletions, as well as over-expression of PCA3 and AMACR, and loss of MSMB in tumour tissue. A subset of the 100 genes outperforms established clinical predictors of poor prognosis (PSA, Gleason score), as well as previously published gene

Multi-laboratory validation study of multilocus variable-number tandem repeat analysis (MLVA) for Salmonella enterica serovar Enteritidis, 2015

PubMed Central

Peters, Tansy; Bertrand, Sophie; Björkman, Jonas T; Brandal, Lin T; Brown, Derek J; Erdõsi, Tímea; Heck, Max; Ibrahem, Salha; Johansson, Karin; Kornschober, Christian; Kotila, Saara M; Le Hello, Simon; Lienemann, Taru; Mattheus, Wesley; Nielsen, Eva Møller; Ragimbeau, Catherine; Rumore, Jillian; Sabol, Ashley; Torpdahl, Mia; Trees, Eija; Tuohy, Alma; de Pinna, Elizabeth

2017-01-01

Multilocus variable-number tandem repeat analysis (MLVA) is a rapid and reproducible typing method that is an important tool for investigation, as well as detection, of national and multinational outbreaks of a range of food-borne pathogens. Salmonella enterica serovar Enteritidis is the most common Salmonella serovar associated with human salmonellosis in the European Union/European Economic Area and North America. Fourteen laboratories from 13 countries in Europe and North America participated in a validation study for MLVA of S. Enteritidis targeting five loci. Following normalisation of fragment sizes using a set of reference strains, a blinded set of 24 strains with known allele sizes was analysed by each participant. The S. Enteritidis 5-loci MLVA protocol was shown to produce internationally comparable results as more than 90% of the participants reported less than 5% discrepant MLVA profiles. All 14 participating laboratories performed well, even those where experience with this typing method was limited. The raw fragment length data were consistent throughout, and the inter-laboratory validation helped to standardise the conversion of raw data to repeat numbers with at least two countries updating their internal procedures. However, differences in assigned MLVA profiles remain between well-established protocols and should be taken into account when exchanging data. PMID:28277220

Multi-laboratory validation study of multilocus variable-number tandem repeat analysis (MLVA) for Salmonella enterica serovar Enteritidis, 2015.

PubMed

Peters, Tansy; Bertrand, Sophie; Björkman, Jonas T; Brandal, Lin T; Brown, Derek J; Erdõsi, Tímea; Heck, Max; Ibrahem, Salha; Johansson, Karin; Kornschober, Christian; Kotila, Saara M; Le Hello, Simon; Lienemann, Taru; Mattheus, Wesley; Nielsen, Eva Møller; Ragimbeau, Catherine; Rumore, Jillian; Sabol, Ashley; Torpdahl, Mia; Trees, Eija; Tuohy, Alma; de Pinna, Elizabeth

2017-03-02

Multilocus variable-number tandem repeat analysis (MLVA) is a rapid and reproducible typing method that is an important tool for investigation, as well as detection, of national and multinational outbreaks of a range of food-borne pathogens. Salmonella enterica serovar Enteritidis is the most common Salmonella serovar associated with human salmonellosis in the European Union/European Economic Area and North America. Fourteen laboratories from 13 countries in Europe and North America participated in a validation study for MLVA of S. Enteritidis targeting five loci. Following normalisation of fragment sizes using a set of reference strains, a blinded set of 24 strains with known allele sizes was analysed by each participant. The S. Enteritidis 5-loci MLVA protocol was shown to produce internationally comparable results as more than 90% of the participants reported less than 5% discrepant MLVA profiles. All 14 participating laboratories performed well, even those where experience with this typing method was limited. The raw fragment length data were consistent throughout, and the inter-laboratory validation helped to standardise the conversion of raw data to repeat numbers with at least two countries updating their internal procedures. However, differences in assigned MLVA profiles remain between well-established protocols and should be taken into account when exchanging data. This article is copyright of The Authors, 2017.

International Space Station Internal Thermal Control System Lab Module Simulator Build-Up and Validation

NASA Technical Reports Server (NTRS)

Wieland, Paul; Miller, Lee; Ibarra, Tom

2003-01-01

As part of the Sustaining Engineering program for the International Space Station (ISS), a ground simulator of the Internal Thermal Control System (ITCS) in the Lab Module was designed and built at the Marshall Space Flight Center (MSFC). To support prediction and troubleshooting, this facility is operationally and functionally similar to the flight system and flight-like components were used when available. Flight software algorithms, implemented using the LabVIEW(Registered Trademark) programming language, were used for monitoring performance and controlling operation. Validation testing of the low temperature loop was completed prior to activation of the Lab module in 2001. Assembly of the moderate temperature loop was completed in 2002 and validated in 2003. The facility has been used to address flight issues with the ITCS, successfully demonstrating the ability to add silver biocide and to adjust the pH of the coolant. Upon validation of the entire facility, it will be capable not only of checking procedures, but also of evaluating payload timelining, operational modifications, physical modifications, and other aspects affecting the thermal control system.

On the validation of a code and a turbulence model appropriate to circulation control airfoils

NASA Technical Reports Server (NTRS)

Viegas, J. R.; Rubesin, M. W.; Maccormack, R. W.

1988-01-01

A computer code for calculating flow about a circulation control airfoil within a wind tunnel test section has been developed. This code is being validated for eventual use as an aid to design such airfoils. The concept of code validation being used is explained. The initial stages of the process have been accomplished. The present code has been applied to a low-subsonic, 2-D flow about a circulation control airfoil for which extensive data exist. Two basic turbulence models and variants thereof have been successfully introduced into the algorithm, the Baldwin-Lomax algebraic and the Jones-Launder two-equation models of turbulence. The variants include adding a history of the jet development for the algebraic model and adding streamwise curvature effects for both models. Numerical difficulties and difficulties in the validation process are discussed. Turbulence model and code improvements to proceed with the validation process are also discussed.

Controlled Hydrogen Fleet and Infrastructure Demonstration and Validation Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stottler, Gary

General Motors, LLC and energy partner Shell Hydrogen, LLC, deployed a system of hydrogen fuel cell electric vehicles integrated with a hydrogen fueling station infrastructure to operate under real world conditions as part of the U.S. Department of Energy's Controlled Hydrogen Fleet and Infrastructure Validation and Demonstration Project. This technical report documents the performance and describes the learnings from progressive generations of vehicle fuel cell system technology and multiple approaches to hydrogen generation and delivery for vehicle fueling.

Ada Compiler Validation Summary Report: Certificate Number: 890409W1. 10063, TeleSoft, TeleGen2 Ada Development System for VAX to E68K, Version 3.23, VAXserver 3602 Host and Motorola MVME117 (MC68010) Target

DTIC Science & Technology

1989-04-09

01hc ’i.’ f’Pf a- ebc 2i1o.-fer-er~hfom Repo.) tUEFCTE $UP1 * ta ~ (Con’rj 01’?Cre V Pot s’o fneccksa’) ortoiorM’f, by blDc n fumYber) Ada Prcr-7n...CLA53SIF1CA1,O0s or IMIS PA ,j (AhnDetsinfree1 AVF Control Number: AVF-VSP-267.0539 69-01-25-TEL Ada COMPILER VALIDATION SUMMARY REPORT: Certificate Number...pragma images controls the creation and allocation of the image table for a specified enumeration type. The default is Deferred, which saves space in the

Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care

PubMed Central

Rennert, Hanna; Eng, Kenneth; Zhang, Tuo; Tan, Adrian; Xiang, Jenny; Romanel, Alessandro; Kim, Robert; Tam, Wayne; Liu, Yen-Chun; Bhinder, Bhavneet; Cyrta, Joanna; Beltran, Himisha; Robinson, Brian; Mosquera, Juan Miguel; Fernandes, Helen; Demichelis, Francesca; Sboner, Andrea; Kluk, Michael; Rubin, Mark A; Elemento, Olivier

2016-01-01

We describe Exome Cancer Test v1.0 (EXaCT-1), the first New York State-Department of Health-approved whole-exome sequencing (WES)-based test for precision cancer care. EXaCT-1 uses HaloPlex (Agilent) target enrichment followed by next-generation sequencing (Illumina) of tumour and matched constitutional control DNA. We present a detailed clinical development and validation pipeline suitable for simultaneous detection of somatic point/indel mutations and copy-number alterations (CNAs). A computational framework for data analysis, reporting and sign-out is also presented. For the validation, we tested EXaCT-1 on 57 tumours covering five distinct clinically relevant mutations. Results demonstrated elevated and uniform coverage compatible with clinical testing as well as complete concordance in variant quality metrics between formalin-fixed paraffin embedded and fresh-frozen tumours. Extensive sensitivity studies identified limits of detection threshold for point/indel mutations and CNAs. Prospective analysis of 337 cancer cases revealed mutations in clinically relevant genes in 82% of tumours, demonstrating that EXaCT-1 is an accurate and sensitive method for identifying actionable mutations, with reasonable costs and time, greatly expanding its utility for advanced cancer care. PMID:28781886

Army Communicator. Volume 38, Number 2. Summer 2013

DTIC Science & Technology

2013-01-01

subject to a penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. 1. REPORT DATE... development and education, without relying solely on operational experience. While waging two wars, many Soldiers sacrificed going to school and...invest in the education and training of our formations. Leadership training is especially important in the Signal Regiment where development of

Guidelines To Validate Control of Cross-Contamination during Washing of Fresh-Cut Leafy Vegetables.

PubMed

Gombas, D; Luo, Y; Brennan, J; Shergill, G; Petran, R; Walsh, R; Hau, H; Khurana, K; Zomorodi, B; Rosen, J; Varley, R; Deng, K

2017-02-01

The U.S. Food and Drug Administration requires food processors to implement and validate processes that will result in significantly minimizing or preventing the occurrence of hazards that are reasonably foreseeable in food production. During production of fresh-cut leafy vegetables, microbial contamination that may be present on the product can spread throughout the production batch when the product is washed, thus increasing the risk of illnesses. The use of antimicrobials in the wash water is a critical step in preventing such water-mediated cross-contamination; however, many factors can affect antimicrobial efficacy in the production of fresh-cut leafy vegetables, and the procedures for validating this key preventive control have not been articulated. Producers may consider three options for validating antimicrobial washing as a preventive control for cross-contamination. Option 1 involves the use of a surrogate for the microbial hazard and the demonstration that cross-contamination is prevented by the antimicrobial wash. Option 2 involves the use of antimicrobial sensors and the demonstration that a critical antimicrobial level is maintained during worst-case operating conditions. Option 3 validates the placement of the sensors in the processing equipment with the demonstration that a critical antimicrobial level is maintained at all locations, regardless of operating conditions. These validation options developed for fresh-cut leafy vegetables may serve as examples for validating processes that prevent cross-contamination during washing of other fresh produce commodities.

Unsteady Low Reynolds Number Aerodynamics for Micro Air Vehicles (MAVs)

DTIC Science & Technology

2010-05-01

and Colonius, T. " Control of a Semi-Circular Planform Wing in a "Gusting" Unsteady Freestream Flow: I- Experimental Issues". AIAA-2008-3976, 2008...information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD...Return 96 6.9.1. Introduction 96 6.9.2. Experimental Parameter Study with Dye Injection 96 6.9.3. Qualitative vs. Quantitative Flow Visualization

Convergent and discriminant validity of measures of parenting efficacy and control.

PubMed

Lovejoy, M C; Verda, M R; Hays, C E

1997-12-01

Examined the convergent and discriminant validity of the Parent Attribution Test (PAT; Bugental, Blue, & Cruzcosa, 1989), the Parental Locus of Control Scale (PLOC; Campis, Lyman, & Prentice-Dunn, 1986), and the Parenting Sense of Competence-Efficacy Scale (PSOC-Efficacy; Johnston & Mash, 1989) in 3 samples of community mothers. In the 1st 2 samples, mothers also completed measures of negative affect and social desirability. In the 3rd sample, the PAT and PSOC-Efficacy scales were administered with measures of adult attachment style and child behavior problems. There was weak support for the convergent validity of the measures. Moreover, the discriminant validity of the measures was not adequately demonstrated. Our results suggest that PLOC and PSOC-Efficacy scores may reflect distress and response style as well as beliefs about parenting. Scores on the PAT, although less influenced by response style and distress, appear to reflect a different dimension of efficacy than that assessed by other self-report measures.

77 FR 5832 - Conveyance of Federally-Owned Mineral Interests; Renewal of OMB Control Number

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-06

...] Conveyance of Federally-Owned Mineral Interests; Renewal of OMB Control Number AGENCY: Bureau of Land... Federally-owned mineral interests. The Office of Management and Budget (OMB) previously approved this...: Title: Conveyance of Federally-Owned Mineral Interests (43 CFR Part 2720). OMB Control Number: 1004-0153...

Environmental Validation of Legionella Control in a VHA Facility Water System.

PubMed

Jinadatha, Chetan; Stock, Eileen M; Miller, Steve E; McCoy, William F

2018-03-01

OBJECTIVES We conducted this study to determine what sample volume, concentration, and limit of detection (LOD) are adequate for environmental validation of Legionella control. We also sought to determine whether time required to obtain culture results can be reduced compared to spread-plate culture method. We also assessed whether polymerase chain reaction (PCR) and in-field total heterotrophic aerobic bacteria (THAB) counts are reliable indicators of Legionella in water samples from buildings. DESIGN Comparative Legionella screening and diagnostics study for environmental validation of a healthcare building water system. SETTING Veterans Health Administration (VHA) facility water system in central Texas. METHODS We analyzed 50 water samples (26 hot, 24 cold) from 40 sinks and 10 showers using spread-plate cultures (International Standards Organization [ISO] 11731) on samples shipped overnight to the analytical lab. In-field, on-site cultures were obtained using the PVT (Phigenics Validation Test) culture dipslide-format sampler. A PCR assay for genus-level Legionella was performed on every sample. RESULTS No practical differences regardless of sample volume filtered were observed. Larger sample volumes yielded more detections of Legionella. No statistically significant differences at the 1 colony-forming unit (CFU)/mL or 10 CFU/mL LOD were observed. Approximately 75% less time was required when cultures were started in the field. The PCR results provided an early warning, which was confirmed by spread-plate cultures. The THAB results did not correlate with Legionella status. CONCLUSIONS For environmental validation at this facility, we confirmed that (1) 100 mL sample volumes were adequate, (2) 10× concentrations were adequate, (3) 10 CFU/mL LOD was adequate, (4) in-field cultures reliably reduced time to get results by 75%, (5) PCR provided a reliable early warning, and (6) THAB was not predictive of Legionella results. Infect Control Hosp Epidemiol 2018;39:259-266.

Validation of the F-18 high alpha research vehicle flight control and avionics systems modifications

NASA Technical Reports Server (NTRS)

Chacon, Vince; Pahle, Joseph W.; Regenie, Victoria A.

1990-01-01

The verification and validation process is a critical portion of the development of a flight system. Verification, the steps taken to assure the system meets the design specification, has become a reasonably understood and straightforward process. Validation is the method used to ensure that the system design meets the needs of the project. As systems become more integrated and more critical in their functions, the validation process becomes more complex and important. The tests, tools, and techniques which are being used for the validation of the high alpha research vehicle (HARV) turning valve control system (TVCS) are discussed, and their solutions are documented. The emphasis of this paper is on the validation of integrated systems.

Validation of the F-18 high alpha research vehicle flight control and avionics systems modifications

NASA Technical Reports Server (NTRS)

Chacon, Vince; Pahle, Joseph W.; Regenie, Victoria A.

1990-01-01

The verification and validation process is a critical portion of the development of a flight system. Verification, the steps taken to assure the system meets the design specification, has become a reasonably understood and straightforward process. Validation is the method used to ensure that the system design meets the needs of the project. As systems become more integrated and more critical in their functions, the validation process becomes more complex and important. The tests, tools, and techniques which are being used for the validation of the high alpha research vehicle (HARV) turning vane control system (TVCS) are discussed and the problems and their solutions are documented. The emphasis of this paper is on the validation of integrated system.

Air & Space Power Journal. Volume 26, Number 2, March-April 2012

DTIC Science & Technology

2012-03-01

subject to a penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. 1. REPORT DATE ...MAR 2012 2. REPORT TYPE 3. DATES COVERED 00-03-2012 to 00-04-2012 4. TITLE AND SUBTITLE Air & Space Power Journal. Volume 26, Number 2, March...Adversaries increasingly target energy as a center of gravity. To date , more than 3,000 American Sol- diers and contractors have been killed or

Revisiting the Basic Reproductive Number for Malaria and Its Implications for Malaria Control

PubMed Central

Smith, David L; McKenzie, F. Ellis; Snow, Robert W; Hay, Simon I

2007-01-01

The prospects for the success of malaria control depend, in part, on the basic reproductive number for malaria, R 0. Here, we estimate R 0 in a novel way for 121 African populations, and thereby increase the number of R 0 estimates for malaria by an order of magnitude. The estimates range from around one to more than 3,000. We also consider malaria transmission and control in finite human populations, of size H. We show that classic formulas approximate the expected number of mosquitoes that could trace infection back to one mosquito after one parasite generation, Z 0(H), but they overestimate the expected number of infected humans per infected human, R 0(H). Heterogeneous biting increases R 0 and, as we show, Z 0(H), but we also show that it sometimes reduces R 0(H); those who are bitten most both infect many vectors and absorb infectious bites. The large range of R 0 estimates strongly supports the long-held notion that malaria control presents variable challenges across its transmission spectrum. In populations where R 0 is highest, malaria control will require multiple, integrated methods that target those who are bitten most. Therefore, strategic planning for malaria control should consider R 0, the spatial scale of transmission, human population density, and heterogeneous biting. PMID:17311470

A Meta-Analysis of the Convergent Validity of Self-Control Measures

PubMed Central

Duckworth, Angela Lee; Kern, Margaret L.

2011-01-01

There is extraordinary diversity in how the construct of self-control is operationalized in research studies. We meta-analytically examined evidence of convergent validity among executive function, delay of gratification, and self- and informant-report questionnaire measures of self-control. Overall, measures demonstrated moderate convergence (rrandom = .27 [95% CI = .24, .30]; rfixed = .34 [.33, .35], k = 282 samples, N = 33,564 participants), although there was substantial heterogeneity in the observed correlations. Correlations within and across types of self-control measures were strongest for informant-report questionnaires and weakest for executive function tasks. Questionnaires assessing sensation seeking impulses could be distinguished from questionnaires assessing processes of impulse regulation. We conclude that self-control is a coherent but multidimensional construct best assessed using multiple methods. PMID:21643479

Validation of MIL-F-9490D. General Specification for Flight Control System for Piloted Military Aircraft. Volume III. C-5A Heavy Logistics Transport Validation

DTIC Science & Technology

1977-04-01

U* AFFDL-TR-77-7 0 VOLUME III " 󈧦 VALIDATION OF MIL-F-9490D - GENERAL SPECIFICATION FOR FLIGHT CONTROL SYSTEM "FOR PILOTED MILITARY AIRCRAFT VOLUME...ý A1O 1 C I\\.FFBL Ti(-77-7. Vol. III f Validatio~n of UL-P-9-490D#,*. General Spacificatior "~inal 1’l -_t e for Flight ContrsA Zyn’om for Piloted...cation MIL-F-9490D (USAF), "Flight Control Systems - Design, Installation and Test of Piloted Aircraft, General Specifications for," dated 6 June 1975, by

QTL Mapping of Kernel Number-Related Traits and Validation of One Major QTL for Ear Length in Maize.

PubMed

Huo, Dongao; Ning, Qiang; Shen, Xiaomeng; Liu, Lei; Zhang, Zuxin

2016-01-01

The kernel number is a grain yield component and an important maize breeding goal. Ear length, kernel number per row and ear row number are highly correlated with the kernel number per ear, which eventually determines the ear weight and grain yield. In this study, two sets of F2:3 families developed from two bi-parental crosses sharing one inbred line were used to identify quantitative trait loci (QTL) for four kernel number-related traits: ear length, kernel number per row, ear row number and ear weight. A total of 39 QTLs for the four traits were identified in the two populations. The phenotypic variance explained by a single QTL ranged from 0.4% to 29.5%. Additionally, 14 overlapping QTLs formed 5 QTL clusters on chromosomes 1, 4, 5, 7, and 10. Intriguingly, six QTLs for ear length and kernel number per row overlapped in a region on chromosome 1. This region was designated qEL1.10 and was validated as being simultaneously responsible for ear length, kernel number per row and ear weight in a near isogenic line-derived population, suggesting that qEL1.10 was a pleiotropic QTL with large effects. Furthermore, the performance of hybrids generated by crossing 6 elite inbred lines with two near isogenic lines at qEL1.10 showed the breeding value of qEL1.10 for the improvement of the kernel number and grain yield of maize hybrids. This study provides a basis for further fine mapping, molecular marker-aided breeding and functional studies of kernel number-related traits in maize.

46 CFR 147.8 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2011 CFR

2011-10-01

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2013-10-01

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46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 5 2012-10-01 2012-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 150.105 Section 150.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant to...

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2014-10-01

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46 CFR 147.8 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

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2012-10-01

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46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2011 CFR

2011-10-01

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46 CFR 147.8 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2014 CFR

2014-10-01

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46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 5 2013-10-01 2013-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 150.105 Section 150.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant to...

46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 5 2010-10-01 2010-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 150.105 Section 150.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant to...

46 CFR 147.8 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2010 CFR

2010-10-01

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46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2014 CFR

2014-10-01

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46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 107.05 Section 107.05 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned...

46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 107.05 Section 107.05 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned...

46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2013 CFR

2013-10-01

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46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 107.05 Section 107.05 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned...

[External and internal validity of a multidimensional Locus of control scale of eating attitudes for athletes (LOCSCAS)].

PubMed

Paquet, Y; Scoffier, S; d'Arripe-Longueville, F

2016-10-01

In the field of health psychology, the control has consistently been considered as a protective factor. This protective role has been also highlighted in eating attitudes' domain. However, current studies use the one-dimensional scale of Rotter or the multidimensional health locus of control scale, and no specific eating attitudes' scale in the sport context exists. Moreover, the social influence in previous scales is limited. According to recent works, the purpose of this study was to test the internal and external validity of a multidimensional locus of control scale of eating attitudes for athletes. One hundred and seventy-nine participants were solicited. A confirmatory factorial analysis was conducted in order to test the internal validity of the scale. The scale external validity was tested in relation to eating attitudes. The internal validity of the scale was verified as well as the external validity, which confirmed the importance of taking into consideration social influences. Indeed, the 2 subscales "Trainers, friends" and "Parents, family" are related respectively positively and negatively in eating disorders. Copyright © 2016 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

FPGA and USB based control board for quantum random number generator

NASA Astrophysics Data System (ADS)

Wang, Jian; Wan, Xu; Zhang, Hong-Fei; Gao, Yuan; Chen, Teng-Yun; Liang, Hao

2009-09-01

The design and implementation of FPGA-and-USB-based control board for quantum experiments are discussed. The usage of quantum true random number generator, control- logic in FPGA and communication with computer through USB protocol are proposed in this paper. Programmable controlled signal input and output ports are implemented. The error-detections of data frame header and frame length are designed. This board has been used in our decoy-state based quantum key distribution (QKD) system successfully.

7 CFR 215.18 - Information collection/recordkeeping-OMB assigned control numbers.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL MILK PROGRAM FOR CHILDREN § 215.18 Information collection/recordkeeping—OMB assigned control numbers. 7 CFR section where...

7 CFR 215.18 - Information collection/recordkeeping-OMB assigned control numbers.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL MILK PROGRAM FOR CHILDREN § 215.18 Information collection/recordkeeping—OMB assigned control numbers. 7 CFR section where...

7 CFR 215.18 - Information collection/recordkeeping-OMB assigned control numbers.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL MILK PROGRAM FOR CHILDREN § 215.18 Information collection/recordkeeping—OMB assigned control numbers. 7 CFR section where...

7 CFR 215.18 - Information collection/recordkeeping-OMB assigned control numbers.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL MILK PROGRAM FOR CHILDREN § 215.18 Information collection/recordkeeping—OMB assigned control numbers. 7 CFR section where...

7 CFR 215.18 - Information collection/recordkeeping-OMB assigned control numbers.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL MILK PROGRAM FOR CHILDREN § 215.18 Information collection/recordkeeping—OMB assigned control numbers. 7 CFR section where...

Evaluation of a Quartz Bourdon Pressure Gage of Wind Tunnel Mach Number Control System Application

NASA Technical Reports Server (NTRS)

Chapin, W. G.

1986-01-01

A theoretical and experimental study was undertaken to determine the feasibility of using the National Transonic Facility's high accuracy Mach number measurement system as part of a closed loop Mach number control system. The theoretical and experimental procedures described are applicable to the engineering design of pressure control systems. The results show that the dynamic response characteristics of the NTF Mach number gage (a Ruska DDR-6000 quartz absolute pressure gage) coupled to a typical length of pressure tubing were only marginally acceptable within a limited range of the facility's total pressure envelope and could not be used in the Mach number control system.

12 CFR 24.1 - Authority, purpose, and OMB control number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Authority, purpose, and OMB control number. 24.1 Section 24.1 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY COMMUNITY AND ECONOMIC DEVELOPMENT ENTITIES, COMMUNITY DEVELOPMENT PROJECTS, AND OTHER PUBLIC WELFARE...

9 CFR 355.9 - Numbers granted same ownership or control.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Numbers granted same ownership or control. 355.9 Section 355.9 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... INSPECTION AND CERTIFICATION CERTIFIED PRODUCTS FOR DOGS, CATS, AND OTHER CARNIVORA; INSPECTION...

Validity and reliability of a controlled pneumatic resistance exercise device.

PubMed

Paulus, David C; Reynolds, Michael C; Schilling, Brian K

2008-01-01

During the concentric portion of the free-weight squat exercise, accelerating the mass from rest results in a fluctuation in ground reaction force. It is characterized by an initial period of force greater than the load while accelerating from rest followed by a period of force lower than the external load during negative acceleration. During the deceleration phase, less force is exerted and muscles are loaded sub-optimally. Thus, using a reduced inertia form of resistance such as pneumatics has the capability to minimize these inertial effects as well as control the force in real time to maximize the force exerted over the exercise cycle. To improve the system response of a preliminary design, a squat device was designed with a reduced mass barbell and two smaller pneumatic cylinders. The resistance was controlled by regulating cylinder pressure such that it is capable of adjusting force within a repetition to maximize force exerted during the lift. The resistance force production of the machine was statically validated with the input voltage and output force R2 =0.9997 for at four increments of the range of motion, and the intraclass correlation coefficient (ICC) between trials at the different heights equaled 0.999. The slew rate at three forces was 749.3 N/s +/- 252.3. Dynamic human subject testing showed the desired input force correlated with average and peak ground reaction force with R2 = 0.9981 and R2 = 0.9315, respectively. The ICC between desired force and average and peak ground reaction force was 0.963. Thus, the system is able to deliver constant levels of static and dynamic force with validity and reliability. Future work will be required to develop the control strategy required for real-time control, and performance testing is required to determine its efficacy.

Reynolds number dependence of large-scale friction control in turbulent channel flow

NASA Astrophysics Data System (ADS)

Canton, Jacopo; Örlü, Ramis; Chin, Cheng; Schlatter, Philipp

2016-12-01

The present work investigates the effectiveness of the control strategy introduced by Schoppa and Hussain [Phys. Fluids 10, 1049 (1998), 10.1063/1.869789] as a function of Reynolds number (Re). The skin-friction drag reduction method proposed by these authors, consisting of streamwise-invariant, counter-rotating vortices, was analyzed by Canton et al. [Flow, Turbul. Combust. 97, 811 (2016), 10.1007/s10494-016-9723-8] in turbulent channel flows for friction Reynolds numbers (Reτ) corresponding to the value of the original study (i.e., 104) and 180. For these Re, a slightly modified version of the method proved to be successful and was capable of providing a drag reduction of up to 18%. The present study analyzes the Reynolds number dependence of this drag-reducing strategy by performing two sets of direct numerical simulations (DNS) for Reτ=360 and 550. A detailed analysis of the method as a function of the control parameters (amplitude and wavelength) and Re confirms, on the one hand, the effectiveness of the large-scale vortices at low Re and, on the other hand, the decreasing and finally vanishing effectiveness of this method for higher Re. In particular, no drag reduction can be achieved for Reτ=550 for any combination of the parameters controlling the vortices. For low Reynolds numbers, the large-scale vortices are able to affect the near-wall cycle and alter the wall-shear-stress distribution to cause an overall drag reduction effect, in accordance with most control strategies. For higher Re, instead, the present method fails to penetrate the near-wall region and cannot induce the spanwise velocity variation observed in other more established control strategies, which focus on the near-wall cycle. Despite the negative outcome, the present results demonstrate the shortcomings of the control strategy and show that future focus should be on methods that directly target the near-wall region or other suitable alternatives.

Validation of an Integrated Airframe and Turbofan Engine Simulation for Evaluation of Propulsion Control Modes

NASA Technical Reports Server (NTRS)

Litt, Jonathan S.; Sowers, T Shane; Liu, Yuan; Owen, A. Karl; Guo, Ten-Huei

2015-01-01

The National Aeronautics and Space Administration (NASA) has developed independent airframe and engine models that have been integrated into a single real-time aircraft simulation for piloted evaluation of propulsion control algorithms. In order to have confidence in the results of these evaluations, the integrated simulation must be validated to demonstrate that its behavior is realistic and that it meets the appropriate Federal Aviation Administration (FAA) certification requirements for aircraft. The paper describes the test procedures and results, demonstrating that the integrated simulation generally meets the FAA requirements and is thus a valid testbed for evaluation of propulsion control modes.

All Validity Is Construct Validity. Or Is It?

ERIC Educational Resources Information Center

Kane, Michael

2012-01-01

Paul E. Newton's article on the consensus definition of validity tackles a number of big issues and makes a number of strong claims. I agreed with much of what he said, and I disagreed with a number of his claims, but I found his article to be consistently interesting and thought provoking (whether I agreed or not). I will focus on three general…

Assessing validity of observational intervention studies – the Benchmarking Controlled Trials

PubMed Central

Malmivaara, Antti

2016-01-01

Abstract Background: Benchmarking Controlled Trial (BCT) is a concept which covers all observational studies aiming to assess impact of interventions or health care system features to patients and populations. Aims: To create and pilot test a checklist for appraising methodological validity of a BCT. Methods: The checklist was created by extracting the most essential elements from the comprehensive set of criteria in the previous paper on BCTs. Also checklists and scientific papers on observational studies and respective systematic reviews were utilized. Ten BCTs published in the Lancet and in the New England Journal of Medicine were used to assess feasibility of the created checklist. Results: The appraised studies seem to have several methodological limitations, some of which could be avoided in planning, conducting and reporting phases of the studies. Conclusions: The checklist can be used for planning, conducting, reporting, reviewing, and critical reading of observational intervention studies. However, the piloted checklist should be validated in further studies.Key messagesBenchmarking Controlled Trial (BCT) is a concept which covers all observational studies aiming to assess impact of interventions or health care system features to patients and populations.This paper presents a checklist for appraising methodological validity of BCTs and pilot-tests the checklist with ten BCTs published in leading medical journals. The appraised studies seem to have several methodological limitations, some of which could be avoided in planning, conducting and reporting phases of the studies.The checklist can be used for planning, conducting, reporting, reviewing, and critical reading of observational intervention studies. PMID:27238631

Development, Validation, and Fairness of a Biographical Data Questionnaire for the Air Traffic Control Specialist Occupation

DTIC Science & Technology

2012-12-01

Development and validation. ABA, BQ , and criterion data were extracted from AT- SAT concurrent, criterion- related validation database. Overall, 1,232...dependent on responses to the other instrument. 3 A subset of 260 controllers in the AT- SAT dataset had full and complete ABA, BQ , and criterion data (i.e... SAT cases with ABA, BQ , and criterion data (n=260) was very small, making fairness analyses with the validation sample impractical. However, the

Validation of the Asthma Control Test questionnaire in a North African population.

PubMed

El Hasnaoui, Abdelkader; Martin, Jennifer; Salhi, Hocine; Doble, Adam

2009-12-01

Patient-reported outcome measures are required to measure asthma control. The Asthma Control Test (ACT) is one such measure which was used in the AIRMAG study, a general population study of asthma in the Maghreb. Three dialectal Arabic versions of the ACT (Algerian, Moroccan and Tunisian) were developed. To perform a psychometric evaluation of the properties of dialectal Arabic versions of the ACT used in the AIRMAG study. The test data came from 624 adult subjects in a random general population sample in Algeria, Morocco and Tunisia. The internal consistency of the ACT was analysed using Cronbach's a coefficient. The factorial structure was explored by primary component analysis with varimax rotation. Test-retest reproducibility was assessed in a subgroup of 61 subjects. Face and discriminant validity were assessed. Cronbach's a coefficient ranged from 0.58 for the Algerian version to 0.67 for the Moroccan version. The 'use-of-rescue-treatment' item was identified as discordant, since its removal resulted in an increase in Cronbach's a coefficient. The discordance of this item was confirmed by primary component analysis, where the four remaining items were aligned along a single dimension, and the 'use-of-rescue-treatment' item offset along a second dimension. Test and retest scores were well correlated (r =0.704). The ACT showed good face and discriminant validity. The ACT is a valid measure of asthma control in a North African context, although its internal consistency is compromised by the 'use-of-rescue-treatment' item, probably due to limited access to care and use of short-acting beta-agonists. (c) 2009 Elsevier Ltd. All rights reserved.

Nanoarchitectonics for Controlling the Number of Dopant Atoms in Solid Electrolyte Nanodots.

PubMed

Nayak, Alpana; Unayama, Satomi; Tai, Seishiro; Tsuruoka, Tohru; Waser, Rainer; Aono, Masakazu; Valov, Ilia; Hasegawa, Tsuyoshi

2018-02-01

Controlling movements of electrons and holes is the key task in developing today's highly sophisticated information society. As transistors reach their physical limits, the semiconductor industry is seeking the next alternative to sustain its economy and to unfold a new era of human civilization. In this context, a completely new information token, i.e., ions instead of electrons, is promising. The current trend in solid-state nanoionics for applications in energy storage, sensing, and brain-type information processing, requires the ability to control the properties of matter at the ultimate atomic scale. Here, a conceptually novel nanoarchitectonic strategy is proposed for controlling the number of dopant atoms in a solid electrolyte to obtain discrete electrical properties. Using α-Ag 2+ δ S nanodots with a finite number of nonstoichiometry excess dopants as a model system, a theory matched with experiments is presented that reveals the role of physical parameters, namely, the separation between electrochemical energy levels and the cohesive energy, underlying atomic-scale manipulation of dopants in nanodots. This strategy can be applied to different nanoscale materials as their properties strongly depend on the number of doping atoms/ions, and has the potential to create a new paradigm based on controlled single atom/ion transfer. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

[Validation of the IBS-SSS].

PubMed

Betz, C; Mannsdörfer, K; Bischoff, S C

2013-10-01

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterised by abdominal pain, associated with stool abnormalities and changes in stool consistency. Diagnosis of IBS is based on characteristic symptoms and exclusion of other gastrointestinal diseases. A number of questionnaires exist to assist diagnosis and assessment of severity of the disease. One of these is the irritable bowel syndrome - severity scoring system (IBS-SSS). The IBS-SSS was validated 1997 in its English version. In the present study, the IBS-SSS has been validated in German language. To do this, a cohort of 60 patients with IBS according to the Rome III criteria, was compared with a control group of healthy individuals (n = 38). We studied sensitivity and reproducibility of the score, as well as the sensitivity to detect changes of symptom severity. The results of the German validation largely reflect the results of the English validation. The German version of the IBS-SSS is also a valid, meaningful and reproducible questionnaire with a high sensitivity to assess changes in symptom severity, especially in IBS patients with moderate symptoms. It is unclear if the IBS-SSS is also a valid questionnaire in IBS patients with severe symptoms because this group of patients was not studied. © Georg Thieme Verlag KG Stuttgart · New York.

Circulation Control Model Experimental Database for CFD Validation

NASA Technical Reports Server (NTRS)

Paschal, Keith B.; Neuhart, Danny H.; Beeler, George B.; Allan, Brian G.

2012-01-01

A 2D circulation control wing was tested in the Basic Aerodynamic Research Tunnel at the NASA Langley Research Center. A traditional circulation control wing employs tangential blowing along the span over a trailing-edge Coanda surface for the purpose of lift augmentation. This model has been tested extensively at the Georgia Tech Research Institute for the purpose of performance documentation at various blowing rates. The current study seeks to expand on the previous work by documenting additional flow-field data needed for validation of computational fluid dynamics. Two jet momentum coefficients were tested during this entry: 0.047 and 0.114. Boundary-layer transition was investigated and turbulent boundary layers were established on both the upper and lower surfaces of the model. Chordwise and spanwise pressure measurements were made, and tunnel sidewall pressure footprints were documented. Laser Doppler Velocimetry measurements were made on both the upper and lower surface of the model at two chordwise locations (x/c = 0.8 and 0.9) to document the state of the boundary layers near the spanwise blowing slot.

Development and validation of a scale to measure perceived control of internal states.

PubMed

Pallant, J F

2000-10-01

One of the key developments in the psychological literature on control has been the growing recognition of the multidimensional nature of the control construct. Recent research suggests that perceived control of internal states may be just as important as perceived control of external events. The Perceived Control of Internal States Scale was developed to provide a measure of the degree to which people feel they have control of their internal states (emotions, thoughts, physical reactions). I report the results of 2 studies (N= 689), supporting the reliability, construct, and incremental validity of the scale. The buffering effects of perceived control for people facing major life events was also explored, with higher levels of perceived control being associated with less physical and psychological symptoms of strain.

The Child Dental Control Assessment (CDCA) in youth: reliability, validity and cross-cultural differences.

PubMed

Coolidge, T; Heima, M; Heaton, L J; Nakai, Y; Höskuldsson, O; Smith, T A; Weinstein, P; Milgrom, P

2005-03-01

The Child Dental Control Assessment (CDCA) measures children's preferred control strategies in the dental situation. Three studies are reported, assessing aspects of this instrument in youths from the USA, Japan and Australia. In particular, measurements were made as to the reliability and validity of this instrument in this age group in the three cultures, as well as comparing some results across cultures. These studies used a questionnaire design. Questionnaires (including the CDCA and other measures) were given to youths aged 11-15 in the three cultures. In one culture, youths received the questionnaire twice, to compute test-retest reliability. The measure's reliability and validity were similar to those of other measures. The CDCA behaves similarly to the Revised Iowa Dental Control Index (R-IDCI). Youths in all three cultures showed similar responses, although the Japanese were less likely to endorse items. Internal reliability of the scale ranged from 0.74 to 0.85. Test- retest reliability was 0.74. Participants in the High Desire/Low Predicted classification on the R-IDCI scored higher on the CDCA (t (73) = 2.9, p < .01). In the Japanese and Australian samples the correlation between CDCA and dental fear was 0.29-0.33 (p < .001). The Australian and USA samples scored significantly higher than the Japanese sample (overall F(2,1544) = 383.98, p < .001, followed by Tukey's HSD, p < .001). These results provide evidence for the reliability and validity of the CDCA in youth. It appears to measure the discrepancy between Desired and Predicted Control identified in the Revised Iowa Dental Control Index (R-IDCI). Responses of the youth in all three cultures were similar, indicating common dental control preferences for individuals of this age. However, consistent with cultural values, Japanese youth were less likely to endorse the control strategies. These results underline the need to develop culturally-specific, as well as situationally-specific control measures.

Protocol for the validation of microbiological control of cellular products according to German regulators recommendations--Boon and Bane for the manufacturer.

PubMed

Störmer, M; Radojska, S; Hos, N J; Gathof, B S

2015-04-01

In order to generate standardized conditions for the microbiological control of HPCs, the PEI recommended defined steps for validation that will lead to extensive validation as shown in this study, where a possible validation principle for the microbiological control of allogeneic SCPs is presented. Although it could be demonstrated that automated culture improves microbial safety of cellular products, the requirement for extensive validation studies needs to be considered. © 2014 International Society of Blood Transfusion.

Validation of copy number variants associated with prostate cancer risk and prognosis.

PubMed

Blackburn, August; Wilson, Desiree; Gelfond, Jonathan; Yao, Li; Hernandez, Javier; Thompson, Ian M; Leach, Robin J; Lehman, Donna M

2014-01-01

Two recent studies have reported novel heritable copy number variants on chromosomes 2p, 15q, and 12q to be associated with prostate cancer (PCa) risk in non-Hispanic Caucasians. The goal of this study was to determine whether these findings could be independently confirmed in the Caucasian population from the South Texas area. The study subjects consisted of participants of the San Antonio Biomarkers of Risk for PCa cohort and additional cases ascertained in the same metropolitan area. We genotyped all 7 of the reported copy number variants using real-time quantitative polymerase chain reaction in 1,536 (317 cases and 1,219 controls) non-Hispanic Caucasian men, and additionally, we genotyped 632 (191 cases and 441 controls) Hispanic Caucasian men for one of these variants, a deletion on 2p24.3. Association of the deletion on 2p24.3 with overall PCa risk did not meet our significance criteria but was consistent with previous reports (odds ratio, 1.40; 95% confidence interval 0.99-2.00; P = 0.06). Among Hispanic Caucasians, this deletion is much less prevalent (minor allele frequencies of 0.059 and 0.024 in non-Hispanic and Hispanic Caucasians, respectively) and did not show evidence of association with risk for PCa. Interestingly, among non-Hispanic Caucasians, carrying a homozygous deletion of 2p24.3 was significantly associated with high-grade PCa as defined by Gleason score sum ≥8 (odds ratio, 27.99; 95% confidence interval 1.99-392.6; P = 0.007 [the Fisher exact test]). The remaining 6 copy number variable regions either were not polymorphic in our cohort of non-Hispanic Caucasians or showed no evidence of association. Our findings are consistent with the reported observation that a heritable deletion on 2p24.3 is associated with PCa risk in non-Hispanic Caucasians. Additionally, our observations indicate that the 2p24.3 variant is associated with risk for high-grade PCa in a recessive manner. We were unable to replicate any association with PCa for the

Validation of the Federal Aviation Administration Air Traffic Control Specialist Pre-Training Screen.

DOT National Transportation Integrated Search

1994-02-01

Two formal validation studies of the Air Traffic Control Specialist Pre Training Screen (ATCS/PTS), a 5 day computer administered test battery, are described. The ATCS/PTS was designed to replace the 9 week US Federal Aviation Administration (FAA) Ac...

Validity and validation of expert (Q)SAR systems.

PubMed

Hulzebos, E; Sijm, D; Traas, T; Posthumus, R; Maslankiewicz, L

2005-08-01

At a recent workshop in Setubal (Portugal) principles were drafted to assess the suitability of (quantitative) structure-activity relationships ((Q)SARs) for assessing the hazards and risks of chemicals. In the present study we applied some of the Setubal principles to test the validity of three (Q)SAR expert systems and validate the results. These principles include a mechanistic basis, the availability of a training set and validation. ECOSAR, BIOWIN and DEREK for Windows have a mechanistic or empirical basis. ECOSAR has a training set for each QSAR. For half of the structural fragments the number of chemicals in the training set is >4. Based on structural fragments and log Kow, ECOSAR uses linear regression to predict ecotoxicity. Validating ECOSAR for three 'valid' classes results in predictivity of > or = 64%. BIOWIN uses (non-)linear regressions to predict the probability of biodegradability based on fragments and molecular weight. It has a large training set and predicts non-ready biodegradability well. DEREK for Windows predictions are supported by a mechanistic rationale and literature references. The structural alerts in this program have been developed with a training set of positive and negative toxicity data. However, to support the prediction only a limited number of chemicals in the training set is presented to the user. DEREK for Windows predicts effects by 'if-then' reasoning. The program predicts best for mutagenicity and carcinogenicity. Each structural fragment in ECOSAR and DEREK for Windows needs to be evaluated and validated separately.

[Validation of a Spanish version of the Childhood Asthma Control Test (Sc-ACT) for use in Spain].

PubMed

Pérez-Yarza, E G; Castro-Rodriguez, J A; Villa Asensi, J R; Garde Garde, J; Hidalgo Bermejo, F J

2015-08-01

The Childhood Asthma Control Test (c-ACT) is a validated tool for determining pediatric asthma control. However, it is not validated in the Spanish language in Spain. We evaluated the psychometric properties of the Spanish version of the Childhood Asthma Control Test (Sc-ACT) for assessing asthma control in children ages 4 to11. This national, multicentre, prospective study was conducted in Spain with asthmatic children and their caregivers. Patients were assessed at 3 visits (Baseline, 2 Weeks, and 4 Months). Clinical variables included: symptoms, exacerbations, FEV1, asthma classification, PAQLQ and PACQLQ questionnaire scores, and asthma control as perceived by physicians, patients and caregivers. The Sc-ACT feasibility, validity, reliability, and sensitivity to change were assessed. A total of 394 children were included; mean (SD) time to complete the Sc-ACT was 5.3 (4.4) minutes. Sc-ACT score was correlated with asthma control as perceived by physician (-0.52), patient (-0.53), and caregiver (-0.51) and with the PAQLQ (0.56) and PACQLQ (0.55) scores. Sc-ACT was found to be significantly related to intensity and frequency of asthma symptoms. Cronbach alpha coefficient α was 0.81 and intraclass correlation coefficient was ≥0.85 for all of the items. The global effect size of Sc-ACT was 0.55. The cutoff point scores of 21 or higher indicated a good asthma control and their MCID was 4 points. The Spanish version of the c-ACT was found to be a reliable and valid questionnaire for evaluating asthma control in Spanish-speaking children ages 4 to 11 in Spain. Copyright © 2014 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.

Ada (Trade Name) Compiler Validation Summary Report: Verdix Corporation VAda-010-20205, Version 5.42 SYS32/20 Host National DB32000 (NS32032) Target.

DTIC Science & Technology

1987-06-21

AD-*I93 60 A (T~r~ OIIP~~~T l UNCL~t Uh 1&0-- is Imf, FILE COPY 0o AVF Control Number: AVF-VSR-100.1087087-04-09- VRX Ada® COMPILER VALIDATION SUMMARY...UNCLASSIFIED SECURITY CLASSIFICATION OF THIS PAGE (When Data Entered) AVF Control Number: AVF-VSR-100.0987 87-04-09- VRX Ada ® COMPILER VALIDATION SUMMARY REPORT

A formal approach to validation and verification for knowledge-based control systems

NASA Technical Reports Server (NTRS)

Castore, Glen

1987-01-01

As control systems become more complex in response to desires for greater system flexibility, performance and reliability, the promise is held out that artificial intelligence might provide the means for building such systems. An obstacle to the use of symbolic processing constructs in this domain is the need for verification and validation (V and V) of the systems. Techniques currently in use do not seem appropriate for knowledge-based software. An outline of a formal approach to V and V for knowledge-based control systems is presented.

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Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-28

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Development and validation of a questionnaire to evaluate infection control in oral radiology.

PubMed

da Costa, Eliana D; Pinelli, Camila; da Silva Tagliaferro, Elaine P; Corrente, José E; Ambrosano, Glaucia M B

2017-04-01

To create and validate a questionnaire to evaluate infection control in oral radiology. The questionnaire was developed after review of the literature, which included published articles and the biosafety protocols available from healthcare agencies. The initial version of the questionnaire was composed of 14 multiple choice questions and was divided into 3 domains on handwashing, disinfection/protection of surfaces and disinfectant used. Content validity was assessed by two expert committees, which reviewed the content and scope of the questionnaire and the relevance of each item, respectively. Reliability was evaluated using test-retest and internal consistency methods with 115 undergraduate dentistry students. Construct validity was assessed using the known-groups technique and factor analysis. The known-groups technique involved 641 undergraduate dentistry students, 20 PhD students and 15 oral radiology professors. In the factor analysis, 3 radiology technicians also participated in addition to the 641 undergraduates, 20 PhD students and 15 oral radiology professors. The content validity results were found to be satisfactory to excellent for the ordinal variables (intraclass correlation coefficient = 0.722-1.000) and good to great for the yes/no questions (kappa = 0.662-0.913) in terms of reliability and good internal consistency (Cronbach's alpha = 0.88). After a factor analysis, some questions were excluded, and the questions were grouped into new domains. Significant differences were observed between answers from different groups. The final version of the questionnaire was composed of nine domains. The questionnaire created was found to exhibit good psychometric properties for assessing infection control in oral radiology.

Number sense in infancy predicts mathematical abilities in childhood.

PubMed

Starr, Ariel; Libertus, Melissa E; Brannon, Elizabeth M

2013-11-05

Human infants in the first year of life possess an intuitive sense of number. This preverbal number sense may serve as a developmental building block for the uniquely human capacity for mathematics. In support of this idea, several studies have demonstrated that nonverbal number sense is correlated with mathematical abilities in children and adults. However, there has been no direct evidence that infant numerical abilities are related to mathematical abilities later in childhood. Here, we provide evidence that preverbal number sense in infancy predicts mathematical abilities in preschool-aged children. Numerical preference scores at 6 months of age correlated with both standardized math test scores and nonsymbolic number comparison scores at 3.5 years of age, suggesting that preverbal number sense facilitates the acquisition of numerical symbols and mathematical abilities. This relationship held even after controlling for general intelligence, indicating that preverbal number sense imparts a unique contribution to mathematical ability. These results validate the many prior studies purporting to show number sense in infancy and support the hypothesis that mathematics is built upon an intuitive sense of number that predates language.

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