Sample records for values obtained experimentally

  1. Obtaining high g-values with low degree expansion of the phasefunction

    NASA Astrophysics Data System (ADS)

    Rinzema, Kees; ten Bosch, Jaap J.; Ferwerda, Hedzer A.; Hoenders, Bernhard J.

    1994-02-01

    Analytic theory of anisotropic random flight requires the expansion of phase-functions in spherical harmonics. The number of terms should be limited while a g value should be obtained that is as high as possible. We describe how such a phase function can be constructed for a given number N of spherical components of the phasefunction, while obtaining a maximum value of the asymmetry parameter g.

  2. On the precision of experimentally determined protein folding rates and φ-values

    PubMed Central

    De Los Rios, Miguel A.; Muralidhara, B.K.; Wildes, David; Sosnick, Tobin R.; Marqusee, Susan; Wittung-Stafshede, Pernilla; Plaxco, Kevin W.; Ruczinski, Ingo

    2006-01-01

    φ-Values, a relatively direct probe of transition-state structure, are an important benchmark in both experimental and theoretical studies of protein folding. Recently, however, significant controversy has emerged regarding the reliability with which φ-values can be determined experimentally: Because φ is a ratio of differences between experimental observables it is extremely sensitive to errors in those observations when the differences are small. Here we address this issue directly by performing blind, replicate measurements in three laboratories. By monitoring within- and between-laboratory variability, we have determined the precision with which folding rates and φ-values are measured using generally accepted laboratory practices and under conditions typical of our laboratories. We find that, unless the change in free energy associated with the probing mutation is quite large, the precision of φ-values is relatively poor when determined using rates extrapolated to the absence of denaturant. In contrast, when we employ rates estimated at nonzero denaturant concentrations or assume that the slopes of the chevron arms (mf and mu) are invariant upon mutation, the precision of our estimates of φ is significantly improved. Nevertheless, the reproducibility we thus obtain still compares poorly with the confidence intervals typically reported in the literature. This discrepancy appears to arise due to differences in how precision is calculated, the dependence of precision on the number of data points employed in defining a chevron, and interlaboratory sources of variability that may have been largely ignored in the prior literature. PMID:16501226

  3. A new look on anomalous thermal gradient values obtained in South Portugal

    NASA Astrophysics Data System (ADS)

    Duque, M. R.; Malico, I.

    2012-04-01

    A NEW LOOK ON THE ANOMALOUS THERMAL GRADIENT VALUES OBTAINED IN SOUTH PORTUGAL Duque, M. R. and Malico, I. M. Physics Department, University of Évora, Rua Romão Ramalho, 59,7000-671, Évora, Portugal It is well known that soil temperatures can be altered by water circulation. In this paper, we study numerically this effect by simulating some aquifers occurring in South Portugal. At this location, the thermal gradient values obtained in boreholes with depths less than 200 m, range between 22 and 30 °C km-1. However, there, it is easy to find places where temperatures are around 30 °C, at depths of 100 m. The obtained thermal gradient values show an increase one day after raining and a decrease during the dry season. Additionally, the curve of temperature as function of depth showed no hot water inlet in the hole. The region studied shows a smooth topography due to intensive erosion, but it was affected by alpine and hercinian orogenies. As a result, a high topography in depth, with folds and wrinkles is present. The space between adjacent folds is now filled by small sedimentary basins. Aquifers existing in this region can reach considerable depths and return to depths near the surface, but hot springs in the area are scarce. Water temperature rises in depth, and when the speed is high enough high temperatures near the surface, due to water circulation, can be found. The ability of the fluid to flow through the system depends on topography relief, rock permeability and basal heat flow. In this study, the steady-state fluid flow and heat transfer by conduction and advection are modeled. Fractures in the medium are simulated by an equivalent porous medium saturated with liquid. Thermal conductivity values for the water and the rocks can vary in space .Porosities used have high values in the region of the aquifer, low values in the lower region of the model and intermediate values in the upper regions. The results obtained show that temperature anomaly values

  4. Total sperm per ejaculate of men: obtaining a meaningful value or a mean value with appropriate precision.

    PubMed

    Amann, Rupert P; Chapman, Phillip L

    2009-01-01

    We retrospectively mined and modeled data to answer 3 questions. 1) Relative to an estimate based on approximately 20 semen samples, how imprecise is an estimate of an individual's total sperm per ejaculate (TSperm) based on 1 sample? 2) What is the impact of abstinence interval on TSperm and TSperm/h? 3) How many samples are needed to provide a meaningful estimate of an individual's mean TSperm or TSperm/h? Data were for 18-20 consecutive masturbation samples from each of 48 semen donors. Modeling exploited the gamma distribution of values for TSperm and a unique approach to project to future samples. Answers: 1) Within-individual coefficients of variation were similar for TSperm or TSperm/h abstinence and ranged from 17% to 51%; average approximately 34%. TSperm or TSperm/h in any individual sample from a given donor was between -20% and +20% of the mean value in 48% of 18-20 samples per individual. 2) For a majority of individuals, TSperm increased in a nearly linear manner through approximately 72 hours of abstinence. TSperm and TSperm/h after 18-36 hours' abstinence are high. To obtain meaningful values for diagnostic purposes and maximize distinction of individuals with relatively low or high sperm production, the requested abstinence should be 42-54 hours with an upper limit of 64 hours. For individuals producing few sperm, 7 days or more of abstinence might be appropriate to obtain sperm for insemination. 3) At least 3 samples from a hypothetical future subject are recommended for most applications. Assuming 60 hours' abstinence, 80% confidence limits for TSperm/h for 1, 3, or 6 samples would be 70%-163%, 80%-130%, or 85%-120% of the mean for observed values. In only approximately 50% of cases would TSperm/h for a single sample be within -16% and +30% of the true mean value for that subject. Pooling values for TSperm in samples obtained after 18-36 or 72-168 hours' abstinence with values for TSperm obtained after 42-64 hours is inappropriate. Reliance on

  5. Experimental Demonstration of Higher Precision Weak-Value-Based Metrology Using Power Recycling

    NASA Astrophysics Data System (ADS)

    Wang, Yi-Tao; Tang, Jian-Shun; Hu, Gang; Wang, Jian; Yu, Shang; Zhou, Zong-Quan; Cheng, Ze-Di; Xu, Jin-Shi; Fang, Sen-Zhi; Wu, Qing-Lin; Li, Chuan-Feng; Guo, Guang-Can

    2016-12-01

    The weak-value-based metrology is very promising and has attracted a lot of attention in recent years because of its remarkable ability in signal amplification. However, it is suggested that the upper limit of the precision of this metrology cannot exceed that of classical metrology because of the low sample size caused by the probe loss during postselection. Nevertheless, a recent proposal shows that this probe loss can be reduced by the power-recycling technique, and thus enhance the precision of weak-value-based metrology. Here we experimentally realize the power-recycled interferometric weak-value-based beam-deflection measurement and obtain the amplitude of the detected signal and white noise by discrete Fourier transform. Our results show that the detected signal can be strengthened by power recycling, and the power-recycled weak-value-based signal-to-noise ratio can surpass the upper limit of the classical scheme, corresponding to the shot-noise limit. This work sheds light on higher precision metrology and explores the real advantage of the weak-value-based metrology over classical metrology.

  6. Theoretical verification of experimentally obtained conformation-dependent electronic conductance in a biphenyl molecule

    NASA Astrophysics Data System (ADS)

    Maiti, Santanu K.

    2014-07-01

    The experimentally obtained (Venkataraman et al. [1]) cosine squared relation of electronic conductance in a biphenyl molecule is verified theoretically within a tight-binding framework. Using Green's function formalism we numerically calculate two-terminal conductance as a function of relative twist angle among the molecular rings and find that the results are in good agreement with the experimental observation.

  7. Do bacterial cell numbers follow a theoretical Poisson distribution? Comparison of experimentally obtained numbers of single cells with random number generation via computer simulation.

    PubMed

    Koyama, Kento; Hokunan, Hidekazu; Hasegawa, Mayumi; Kawamura, Shuso; Koseki, Shigenobu

    2016-12-01

    We investigated a bacterial sample preparation procedure for single-cell studies. In the present study, we examined whether single bacterial cells obtained via 10-fold dilution followed a theoretical Poisson distribution. Four serotypes of Salmonella enterica, three serotypes of enterohaemorrhagic Escherichia coli and one serotype of Listeria monocytogenes were used as sample bacteria. An inoculum of each serotype was prepared via a 10-fold dilution series to obtain bacterial cell counts with mean values of one or two. To determine whether the experimentally obtained bacterial cell counts follow a theoretical Poisson distribution, a likelihood ratio test between the experimentally obtained cell counts and Poisson distribution which parameter estimated by maximum likelihood estimation (MLE) was conducted. The bacterial cell counts of each serotype sufficiently followed a Poisson distribution. Furthermore, to examine the validity of the parameters of Poisson distribution from experimentally obtained bacterial cell counts, we compared these with the parameters of a Poisson distribution that were estimated using random number generation via computer simulation. The Poisson distribution parameters experimentally obtained from bacterial cell counts were within the range of the parameters estimated using a computer simulation. These results demonstrate that the bacterial cell counts of each serotype obtained via 10-fold dilution followed a Poisson distribution. The fact that the frequency of bacterial cell counts follows a Poisson distribution at low number would be applied to some single-cell studies with a few bacterial cells. In particular, the procedure presented in this study enables us to develop an inactivation model at the single-cell level that can estimate the variability of survival bacterial numbers during the bacterial death process. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Understanding AlN Obtaining Through Computational Thermodynamics Combined with Experimental Investigation

    NASA Astrophysics Data System (ADS)

    Florea, R. M.

    2017-06-01

    Basic material concept, technology and some results of studies on aluminum matrix composite with dispersive aluminum nitride reinforcement was shown. Studied composites were manufactured by „in situ” technique. Aluminum nitride (AlN) has attracted large interest recently, because of its high thermal conductivity, good dielectric properties, high flexural strength, thermal expansion coefficient matches that of Si and its non-toxic nature, as a suitable material for hybrid integrated circuit substrates. AlMg alloys are the best matrix for AlN obtaining. Al2O3-AlMg, AlN-Al2O3, and AlN-AlMg binary diagrams were thermodynamically modelled. The obtained Gibbs free energies of components, solution parameters and stoichiometric phases were used to build a thermodynamic database of AlN- Al2O3-AlMg system. Obtaining of AlN with Liquid-phase of AlMg as matrix has been studied and compared with the thermodynamic results. The secondary phase microstructure has a significant effect on the final thermal conductivity of the obtained AlN. Thermodynamic modelling of AlN-Al2O3-AlMg system provided an important basis for understanding the obtaining behavior and interpreting the experimental results.

  9. An experimental study of trace element partitioning between perovskite, hibonite and melt: Equilibrium values

    NASA Technical Reports Server (NTRS)

    Kennedy, A. K.; Lofgren, G. E.; Wasserburg, G. J.

    1993-01-01

    The presence of perovskite (CATiO3) and hibonite (Ca Al12O19) within different regions of Calcium-, Aluminum-rich Inclusions (CAI) and the trace element concentrations of these minerals in each circumstance, constrain models of precursor formation, nebular condensation, the thermal history of inclusions with relict perovskite and hibonite, and the formation of the Wark-Lovering rim. At present mineral/melt partition coefficient data for hibonite are limited to a few elements in simple experimental systems, or to those derived from hibonite-glass pairs in hibonite/glass microspherules. Similarly, there is only limited data on perovskite D that are applicable to meteorite compositions. Apart from the importance of partitioning studies to meteorite research, D values also are invaluable in the development of thermodynamic models, especially when data is available for a large number of elements that have different ionic charge and radii. In addition, study of the effect of rapid cooling on partitioning is crucial to our understanding of meteorite inclusions. To expand our knowledge of mineral/melt D for perovskite and hibonite, a study was instituted where D values are obtained in both equilibrium and dynamic cooling experiments. As an initial phase of this study mineral/melt D was measured for major elements (Ca, Mg, Al, Ti, and Si), 15 rare earth elements (La-Lu) and 8 other elements (Ba, Sr, U, Th, Nb, Zr, Hf, and Ge) in perovskite and hibonite grown under equilibrium conditions, in bulk compositions that are respectively similar to Compact Type A (CTA) CAI and to a hibonite/glass microspherule. Experimental mixes were doped with REE at 20-50x chondritic (ch) abundances, Ba at 50 ppm, Sr, Hf, Nb, and Zr at 100 ppm and, U and Th at 200 ppm. Trace element abundances were measured with the PANURGE ion microprobe. Major element compositions were obtained by electron microprobe analysis.

  10. Experimental Characterization of Aluminum-Based Hybrid Composites Obtained Through Powder Metallurgy

    NASA Astrophysics Data System (ADS)

    Marcu, D. F.; Buzatu, M.; Ghica, V. G.; Petrescu, M. I.; Popescu, G.; Niculescu, F.; Iacob, G.

    2018-06-01

    The paper presents some experimental results concerning fabrication through powder metallurgy (P/M) of aluminum-based hybrid composites - Al/Al2O3/Gr. In order to understand the mechanisms that occur during the P/M processes of obtaining Al/Al2O3/Gr composite, we correlated the physical characteristics with their micro-structural characteristics. The characterization was performed using analysis techniques specific for P/M process, SEM-EDS and XRD analyses. Micro-structural characterization of the composites has revealed fairly uniform distribution this resulting in good properties of the final composite material.

  11. Experimental thermal conductivity, thermal diffusivity, and specific heat values for mixtures of nitrogen, oxygen, and argon

    NASA Technical Reports Server (NTRS)

    Perkins, R. A.; Cieszkiewicz, M. T.

    1991-01-01

    Experimental measurements of thermal conductivity and thermal diffusivity obtained with a transient hot-wire apparatus are reported for three mixtures of nitrogen, oxygen, and argon. Values of the specific heat, Cp, are calculated from these measured values and the density calculated with an equation of state. The measurements were made at temperatures between 65 and 303 K with pressures between 0.1 and 70 MPa. The data cover the vapor, liquid, and supercritical gas phases for the three mixtures. The total reported points are 1066 for the air mixture (78.11 percent nitrogen, 20.97 percent oxygen, and 0.92 percent argon), 1058 for the 50 percent nitrogen, 50 percent oxygen mixture, and 864 for the 25 percent nitrogen, 75 oxygen mixture. Empirical thermal conductivity correlations are provided for the three mixtures.

  12. Experimental scarcity increases the relative reinforcing value of food in food insecure adults.

    PubMed

    Crandall, Amanda K; Temple, Jennifer L

    2018-05-29

    People with fewer financial resources are at greater risk for obesity, but the mechanisms of this relationship are not fully understood. One factor that is related, both cross-sectionally and prospectively, to obesity is the relative reinforcing value of food. It is possible that the experience of scarcity increases this reinforcing value. To date, no studies have examined this potential relationship experimentally in humans. The purpose of the studies presented here was to test the hypothesis that experimental manipulations of perceived scarcity would impact the relative reinforcing value of food. A secondary hypothesis was that individuals who report experiencing food insecurity would be more sensitive to these experimental manipulations. In order to test these hypotheses, we investigated the effects of experimentally manipulated scarcity on the relative reinforcing value of food in a laboratory setting. Study 1 had a within-subjects design and included 25 adults. Scarcity was manipulated by placing time and resource limits on the relative reinforcing value task and examining responding for a high calorie snack food versus that of an alternative reinforcer. Study 1 showed a tendency for food insecure participants to respond more for all reinforcers across conditions and have a higher proportional response for food when resources were limited. Study 2 also made use of a within-subjects design with 30 adults and primed scarcity by creating financial gains and losses on the Iowa Gambling Task. We observed higher relative reinforcing values of food among food insecure participants in the control condition, which decreased in the financial gain condition. When taken together, these two studies suggest that individuals who report experiencing food insecurity respond to acute manipulations of scarcity by increasing their reinforcing value of snack food. Copyright © 2018 Elsevier Ltd. All rights reserved.

  13. Determination of Soil Moisture Content using Laboratory Experimental and Field Electrical Resistivity Values

    NASA Astrophysics Data System (ADS)

    Hazreek, Z. A. M.; Rosli, S.; Fauziah, A.; Wijeyesekera, D. C.; Ashraf, M. I. M.; Faizal, T. B. M.; Kamarudin, A. F.; Rais, Y.; Dan, M. F. Md; Azhar, A. T. S.; Hafiz, Z. M.

    2018-04-01

    The efficiency of civil engineering structure require comprehensive geotechnical data obtained from site investigation. In the past, conventional site investigation was heavily related to drilling techniques thus suffer from several limitations such as time consuming, expensive and limited data collection. Consequently, this study presents determination of soil moisture content using laboratory experimental and field electrical resistivity values (ERV). Field and laboratory electrical resistivity (ER) test were performed using ABEM SAS4000 and Nilsson400 soil resistance meter. Soil sample used for resistivity test was tested for characterization test specifically on particle size distribution and moisture content test according to BS1377 (1990). Field ER data was processed using RES2DINV software while laboratory ER data was analyzed using SPSS and Excel software. Correlation of ERV and moisture content shows some medium relationship due to its r = 0.506. Moreover, coefficient of determination, R2 analyzed has demonstrate that the statistical correlation obtain was very good due to its R2 value of 0.9382. In order to determine soil moisture content based on statistical correlation (w = 110.68ρ-0.347), correction factor, C was established through laboratory and field ERV given as 19.27. Finally, this study has shown that soil basic geotechnical properties with particular reference to water content was applicably determined using integration of laboratory and field ERV data analysis thus able to compliment conventional approach due to its economic, fast and wider data coverage.

  14. Evaluation of True Power Luminous Efficiency from Experimental Luminance Values

    NASA Astrophysics Data System (ADS)

    Tsutsui, Tetsuo; Yamamato, Kounosuke

    1999-05-01

    A method for obtaining true external power luminous efficiencyfrom experimentally obtained luminance in organic light-emittingdiodes (LEDs) wasdemonstrated. Conventional two-layer organic LEDs with different electron-transport layer thicknesses wereprepared. Spatial distributions of emission intensities wereobserved. The large deviation in both emission spectra and spatialemission patterns were observed when the electron-transport layerthickness was varied. The deviation of emission patterns from thestandard Lambertian pattern was found to cause overestimations ofpower luminous efficiencies as large as 30%. A method for evaluatingcorrection factors was proposed.

  15. 41 CFR 102-75.305 - What type of appraisal value must be obtained for real property disposal transactions?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What type of appraisal value must be obtained for real property disposal transactions? 102-75.305 Section 102-75.305 Public...-75.305 What type of appraisal value must be obtained for real property disposal transactions? For all...

  16. 41 CFR 102-75.305 - What type of appraisal value must be obtained for real property disposal transactions?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What type of appraisal value must be obtained for real property disposal transactions? 102-75.305 Section 102-75.305 Public...-75.305 What type of appraisal value must be obtained for real property disposal transactions? For all...

  17. 41 CFR 102-75.305 - What type of appraisal value must be obtained for real property disposal transactions?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false What type of appraisal value must be obtained for real property disposal transactions? 102-75.305 Section 102-75.305 Public...-75.305 What type of appraisal value must be obtained for real property disposal transactions? For all...

  18. 41 CFR 102-75.305 - What type of appraisal value must be obtained for real property disposal transactions?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What type of appraisal value must be obtained for real property disposal transactions? 102-75.305 Section 102-75.305 Public...-75.305 What type of appraisal value must be obtained for real property disposal transactions? For all...

  19. 41 CFR 102-75.305 - What type of appraisal value must be obtained for real property disposal transactions?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What type of appraisal value must be obtained for real property disposal transactions? 102-75.305 Section 102-75.305 Public...-75.305 What type of appraisal value must be obtained for real property disposal transactions? For all...

  20. The equivalence of numbers: The social value of avoiding health decline: An experimental web-based study

    PubMed Central

    Schwappach, David LB

    2002-01-01

    Background Health economic analysis aimed at informing policy makers and supporting resource allocation decisions has to evaluate not only improvements in health but also avoided decline. Little is known however, whether the "direction" in which changes in health are experienced is important for the public in prioritizing among patients. This experimental study investigates the social value people place on avoiding (further) health decline when directly compared to curative treatments in resource allocation decisions. Methods 127 individuals completed an interactive survey that was published in the World Wide Web. They were confronted with a standard gamble (SG) and three person trade-off tasks, either comparing improvements in health (PTO-Up), avoided decline (PTO-Down), or both, contrasting health changes of equal magnitude differing in the direction in which they are experienced (PTO-WAD). Finally, a direct priority ranking of various interventions was obtained. Results Participants strongly prioritized improving patients' health rather than avoiding decline. The mean substitution rate between health improvements and avoided decline (WAD) ranged between 0.47 and 0.64 dependent on the intervention. Weighting PTO values according to the direction in which changes in health are experienced improved their accuracy in predicting a direct prioritization ranking. Health state utilities obtained by the standard gamble method seem not to reflect social values in resource allocation contexts. Conclusion Results suggest that the utility of being cured of a given health state might not be a good approximation for the societal value of avoiding this health state, especially in cases of competition between preventive and curative interventions. PMID:11879529

  1. Experimental Surface Pressure Data Obtained on 65 deg Delta Wing Across Reynolds Number and Mach Number Ranges. Volume 2; Small-Radius Leading Edge

    NASA Technical Reports Server (NTRS)

    Chu, Julio; Luckring, James M.

    1996-01-01

    An experimental wind tunnel test of a 65 deg. delta wing model with interchangeable leading edges was conducted in the Langley National Transonic Facility (NTF). The objective was to investigate the effects of Reynolds and Mach numbers on slender-wing leading-edge vortex flows with four values of wing leading-edge bluntness. Experimentally obtained pressure data are presented without analysis in tabulated and graphical formats across a Reynolds number range of 6 x 10(exp 6) to 84 x 10(exp 6) at a Mach number of 0.85 and across a Mach number range of 0.4 to 0.9 at Reynolds numbers of 6 x 10(exp 6) and 60 x 10(exp 6). Normal-force and pitching-moment coefficient plots for these Reynolds number and Mach number ranges are also presented.

  2. Experimental Surface Pressure Data Obtained on 65 deg Delta Wing Across Reynolds Number and Mach Number Ranges. Vol. 4: Large-radius leading edge

    NASA Technical Reports Server (NTRS)

    Chu, Julio; Luckring, James M.

    1996-01-01

    An experimental wind tunnel test of a 65 deg delta wing model with interchangeable leading edges was conducted in the Langley National Transonic Facility (NTF). The objective was to investigate the effects of Reynolds and Mach numbers on slender-wing leading-edge vortex flows with four values of wing leading-edge bluntness. Experimentally obtained pressure data are presented without analysis in tabulated and graphical formats across a Reynolds number range of 6 x 10(exp 6) to 120 x 10(exp 6) at a Mach number of 0.85 and across a Mach number range of 0.4 to 0.9 at Reynolds numbers of 6 x 10(exp 6) and 60 x 10(exp 6). Normal-force and pitching-moment coefficient plots for these Reynolds number and Mach number ranges are also presented.

  3. Obtaining Approximate Values of Exterior Orientation Elements of Multi-Intersection Images Using Particle Swarm Optimization

    NASA Astrophysics Data System (ADS)

    Li, X.; Li, S. W.

    2012-07-01

    In this paper, an efficient global optimization algorithm in the field of artificial intelligence, named Particle Swarm Optimization (PSO), is introduced into close range photogrammetric data processing. PSO can be applied to obtain the approximate values of exterior orientation elements under the condition that multi-intersection photography and a small portable plane control frame are used. PSO, put forward by an American social psychologist J. Kennedy and an electrical engineer R.C. Eberhart, is a stochastic global optimization method based on swarm intelligence, which was inspired by social behavior of bird flocking or fish schooling. The strategy of obtaining the approximate values of exterior orientation elements using PSO is as follows: in terms of image coordinate observed values and space coordinates of few control points, the equations of calculating the image coordinate residual errors can be given. The sum of absolute value of each image coordinate is minimized to be the objective function. The difference between image coordinate observed value and the image coordinate computed through collinear condition equation is defined as the image coordinate residual error. Firstly a gross area of exterior orientation elements is given, and then the adjustment of other parameters is made to get the particles fly in the gross area. After iterative computation for certain times, the satisfied approximate values of exterior orientation elements are obtained. By doing so, the procedures like positioning and measuring space control points in close range photogrammetry can be avoided. Obviously, this method can improve the surveying efficiency greatly and at the same time can decrease the surveying cost. And during such a process, only one small portable control frame with a couple of control points is employed, and there are no strict requirements for the space distribution of control points. In order to verify the effectiveness of this algorithm, two experiments are

  4. Experimental Surface Pressure Data Obtained on 65 deg Delta Wing Across Reynolds Number and Mach Number Ranges. Vol. 3: Medium-radius leading edge

    NASA Technical Reports Server (NTRS)

    Chu, Julio; Luckring, James M.

    1996-01-01

    An experimental wind tunnel test of a 65 deg delta wing model with interchangeable leading edges was conducted in the Langley National Transonic Facility (NTF). The objective was to investigate the effects of Reynolds and Mach numbers on slender-wing leading-edge vortex flows with four values of wing leading-edge bluntness. Experimentally obtained pressure data are presented without analysis in tabulated and graphical formats across a Reynolds number range of 6 x 10(exp 6) to 120 x 10(exp 6) at a Mach number of 0.85 and across a Mach number range of 0.4 to 0.9 at Reynolds numbers of 6 x 10(exp 6), 60 x 10(exp 6), and 120 x 10(exp 6). Normal-force and pitching-moment coefficient plots for these Reynolds number and Mach number ranges are also presented.

  5. Mapping Bone Mineral Density Obtained by Quantitative Computed Tomography to Bone Volume Fraction

    NASA Technical Reports Server (NTRS)

    Pennline, James A.; Mulugeta, Lealem

    2017-01-01

    Methods for relating or mapping estimates of volumetric Bone Mineral Density (vBMD) obtained by Quantitative Computed Tomography to Bone Volume Fraction (BVF) are outlined mathematically. The methods are based on definitions of bone properties, cited experimental studies and regression relations derived from them for trabecular bone in the proximal femur. Using an experimental range of values in the intertrochanteric region obtained from male and female human subjects, age 18 to 49, the BVF values calculated from four different methods were compared to the experimental average and numerical range. The BVF values computed from the conversion method used data from two sources. One source provided pre bed rest vBMD values in the intertrochanteric region from 24 bed rest subject who participated in a 70 day study. Another source contained preflight vBMD values from 18 astronauts who spent 4 to 6 months on the ISS. To aid the use of a mapping from BMD to BVF, the discussion includes how to formulate them for purpose of computational modeling. An application of the conversions would be used to aid in modeling of time varying changes in vBMD as it relates to changes in BVF via bone remodeling and/or modeling.

  6. Re-evaluation of the reported experimental values of the heat of vaporization of N-methylacetamide

    PubMed Central

    MacKerell, Alexander D.; Shim, Ji Hyun; Anisimov, Victor M.

    2010-01-01

    The accuracy of empirical force fields is inherently related to the quality of the target data used for optimization of the model. With the heat of vaporization (ΔHvap) of N-methylacetamide (NMA), a range of values have been reported as target data for optimization of the nonbond parameters associated with the peptide bond in proteins. In the present work, the original experimental data and Antoine constants used for the determination of the ΔHvap of NMA are reanalyzed. Based on this analysis, the wide range of ΔHvap values reported in the literature are shown to be due to incorrect reporting of the temperatures at which the original values were extracted and limitations in the quality of experimental vapor pressure-temperature data over a wide range of temperatures. Taking these problems into account, a consistent ΔHvap value is extracted from three studies for which experimental data are available. This analysis suggests that the most reliable value for ΔHvap is 13.0±0.1 at 410 K for use in force field optimization studies. The present results also indicate that similar analyses, including analysis of Antoine constants alone, may be of utility when reported ΔHvap values are not consistent for a given neat liquid. PMID:20445813

  7. Comparing the rankings obtained from two biodiversity indices: the Fair Proportion Index and the Shapley Value.

    PubMed

    Wicke, Kristina; Fischer, Mareike

    2017-10-07

    The Shapley Value and the Fair Proportion Index of phylogenetic trees have been frequently discussed as prioritization tools in conservation biology. Both indices rank species according to their contribution to total phylogenetic diversity, allowing for a simple conservation criterion. While both indices have their specific advantages and drawbacks, it has recently been shown that both values are closely related. However, as different authors use different definitions of the Shapley Value, the specific degree of relatedness depends on the specific version of the Shapley Value - it ranges from a high correlation index to equality of the indices. In this note, we first give an overview of the different indices. Then we turn our attention to the mere ranking order provided by either of the indices. We compare the rankings obtained from different versions of the Shapley Value for a phylogenetic tree of European amphibians and illustrate their differences. We then undertake further analyses on simulated data and show that even though the chance of two rankings being exactly identical (when obtained from different versions of the Shapley Value) decreases with an increasing number of taxa, the distance between the two rankings converges to zero, i.e., the rankings are becoming more and more alike. Moreover, we introduce our freely available software package FairShapley, which was implemented in Perl and with which all calculations have been performed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. The amount effect and marginal value.

    PubMed

    Rachlin, Howard; Arfer, Kodi B; Safin, Vasiliy; Yen, Ming

    2015-07-01

    The amount effect of delay discounting (by which the value of larger reward amounts is discounted by delay at a lower rate than that of smaller amounts) strictly implies that value functions (value as a function of amount) are steeper at greater delays than they are at lesser delays. That is, the amount effect and the difference in value functions at different delays are actually a single empirical finding. Amount effects of delay discounting are typically found with choice experiments. Value functions for immediate rewards have been empirically obtained by direct judgment. (Value functions for delayed rewards have not been previously obtained.) The present experiment obtained value functions for both immediate and delayed rewards by direct judgment and found them to be steeper when the rewards were delayed--hence, finding an amount effect with delay discounting. © Society for the Experimental Analysis of Behavior.

  9. Construction of social value or utility-based health indices: the usefulness of factorial experimental design plans.

    PubMed

    Cadman, D; Goldsmith, C

    1986-01-01

    Global indices, which aggregate multiple health or function attributes into a single summary indicator, are useful measures in health research. Two key issues must be addressed in the initial stages of index construction from the universe of possible health and function attributes, which ones should be included in a new index? and how simple can the statistical model be to combine attributes into a single numeric index value? Factorial experimental designs were used in the initial stages of developing a function index for evaluating a program for the care of young handicapped children. Beginning with eight attributes judged important to the goals of the program by clinicians, social preference values for different function states were obtained from 32 parents of handicapped children and 32 members of the community. Using category rating methods each rater scored 16 written multi-attribute case descriptions which contained information about a child's status for all eight attributes. Either a good or poor level of each function attribute and age 3 or 5 years were described in each case. Thus, 2(8) = 256 different cases were rated. Two factorial design plans were selected and used to allocate case descriptions to raters. Analysis of variance determined that seven of the eight clinician selected attributes were required in a social value based index for handicapped children. Most importantly, the subsequent steps of index construction could be greatly simplified by the finding that a simple additive statistical model without complex attribute interaction terms was adequate for the index. We conclude that factorial experimental designs are an efficient, feasible and powerful tool for the initial stages of constructing a multi-attribute health index.

  10. Revision of the experimental electron affinity of BO

    NASA Astrophysics Data System (ADS)

    Rienstra, Jonathan C.; Schaefer, Henry F., III

    1997-05-01

    The experimental electron affinity of BO has proven questionable. We obtained the electron affinity of BO using the large aug-cc-pVQZ basis with SCF, CISD, CISD+Q, CCSD, and CCSD(T) methods and predict a value of 2.57 eV, or 0.55 eV smaller than the latest experimental value. The 2∑+ to 2Π excitation energy of BO has also been obtained with the CCSD(T) method and found to be 2.82 eV.

  11. A discrete choice experiment to obtain a tariff for valuing informal care situations measured with the CarerQol instrument.

    PubMed

    Hoefman, Renske J; van Exel, Job; Rose, John M; van de Wetering, E J; Brouwer, Werner B F

    2014-01-01

    Economic evaluations adopting a societal perspective need to include informal care whenever relevant. However, in practice, informal care is often neglected, because there are few validated instruments to measure and value informal care for inclusion in economic evaluations. The CarerQol, which is such an instrument, measures the impact of informal care on 7 important burden dimensions (CarerQol-7D) and values this in terms of general quality of life (CarerQol-VAS). The objective of the study was to calculate utility scores based on relative utility weights for the CarerQol-7D. These tariffs will facilitate inclusion of informal care in economic evaluations. The CarerQol-7D tariff was derived with a discrete choice experiment conducted as an Internet survey among the general adult population in the Netherlands (N = 992). The choice set contained 2 unlabeled alternatives described in terms of the 7 CarerQol-7D dimensions (level range: "no,"some," and "a lot"). An efficient experimental design with priors obtained from a pilot study (N = 104) was used. Data were analyzed with a panel mixed multinomial parameter model including main and interaction effects of the attributes. The utility attached to informal care situations was significantly higher when this situation was more attractive in terms of fewer problems and more fulfillment or support. The interaction term between the CarerQol-7D dimensions physical health and mental health problems also significantly explained this utility. The tariff was constructed by adding up the relative utility weights per category of all CarerQol-7D dimensions and the interaction term. We obtained a tariff providing standard utility scores for caring situations described with the CarerQol-7D. This facilitates the inclusion of informal care in economic evaluations.

  12. A new experimental procedure of outgassing rate measurement to obtain more precise deposition properties of materials

    NASA Astrophysics Data System (ADS)

    Miyazaki, Eiji; Shimazaki, Kazunori; Numata, Osamu; Waki, Miyuki; Yamanaka, Riyo; Kimoto, Yugo

    2016-09-01

    Outgassing rate measurement, or dynamic outgassing test, is used to obtain outgassing properties of materials, i.e., Total Mass Loss, "TML," and Collected Volatile Condensed Mass, "CVCM." The properties are used as input parameters for executing contamination analysis, e.g., calculating a prediction of deposition mass on a surface in a spacecraft caused by outgassed substances from contaminant sources onboard. It is likely that results obtained by such calculations are affected by the input parameters. Thus, it is important to get a sufficient experimental data set of outgassing rate measurements for extract good outgassing parameters of materials for calculation. As specified in the standard, ASTM E 1559, TML is measured by a QCM sensor kept at cryogenic temperature; CVCMs are measured at certain temperatures. In the present work, the authors propose a new experimental procedure to obtain more precise VCMs from one run of the current test time with the present equipment. That is, two of four CQCMs in the equipment control the temperature to cool step-by-step during the test run. It is expected that the deposition rate, that is sticking coefficient, with respect to temperature could be discovered. As a result, the sticking coefficient can be obtained directly between -50 and 50 degrees C with 5 degrees C step. It looks like the method could be used as an improved procedure for outgassing rate measurement. The present experiment also specified some issues of the new procedure. It will be considered in future work.

  13. Experimental evidence for a new single-event upset (SEU) mode in a CMOS SRAM obtained from model verification

    NASA Technical Reports Server (NTRS)

    Zoutendyk, J. A.; Smith, L. S.; Soli, G. A.; Lo, R. Y.

    1987-01-01

    Modeling of SEU has been done in a CMOS static RAM containing 1-micron-channel-length transistors fabricated from a p-well epilayer process using both circuit-simulation and numerical-simulation techniques. The modeling results have been experimentally verified with the aid of heavy-ion beams obtained from a three-stage tandem van de Graaff accelerator. Experimental evidence for a novel SEU mode in an ON n-channel device is presented.

  14. Effect of Fluid Bypassing on the Experimentally Obtained Darcy and Non-Darcy Permeability Parameters of Ceramic Foam Filters

    NASA Astrophysics Data System (ADS)

    Akbarnejad, Shahin; Saffari Pour, Mohsen; Jonsson, Lage Tord Ingemar; Jönsson, Pӓr Göran

    2017-02-01

    Ceramic foam filters (CFFs) are used to remove solid particles and inclusions from molten metal. In general, molten metal which is poured on the top of a CFF needs to reach a certain height to build the required pressure (metal head) to prime the filter. To estimate the required metal head, it is necessary to obtain permeability coefficients using permeametry experiments. It has been mentioned in the literature that to avoid fluid bypassing, during permeametry, samples need to be sealed. However, the effect of fluid bypassing on the experimentally obtained pressure gradients seems not to be explored. Therefore, in this research, the focus was on studying the effect of fluid bypassing on the experimentally obtained pressure gradients as well as the empirically obtained Darcy and non-Darcy permeability coefficients. Specifically, the aim of the research was to investigate the effect of fluid bypassing on the liquid permeability of 30, 50, and 80 pores per inch (PPI) commercial alumina CFFs. In addition, the experimental data were compared to the numerically modeled findings. Both studies showed that no sealing results in extremely poor estimates of the pressure gradients and Darcy and non-Darcy permeability coefficients for all studied filters. The average deviations between the pressure gradients of the sealed and unsealed 30, 50, and 80 PPI samples were calculated to be 57.2, 56.8, and 61.3 pct. The deviations between the Darcy coefficients of the sealed and unsealed 30, 50, and 80 PPI samples found to be 9, 20, and 31 pct. The deviations between the non-Darcy coefficients of the sealed and unsealed 30, 50, and 80 PPI samples were calculated to be 59, 58, and 63 pct.

  15. Transition from Research to Operations: Assessing Value of Experimental Forecast Products within the NWSFO Environment

    NASA Technical Reports Server (NTRS)

    Lapenta, William M.; Wohlman, Richard; Bradshaw, Tom; Burks, Jason; Jedlovec, Gary; Goodman, Steve; Darden, Chris; Meyer, Paul

    2003-01-01

    The NASA Short-term Prediction Research and Transition (SPoRT) Center seeks to accelerate the infusion of NASA Earth Science Enterprise (ESE) observations, data assimilation and modeling research into NWS forecast operations and decision-making. To meet long-term program expectations, it is not sufficient simply to give forecasters sophisticated workstations or new forecast products without fully assessing the ways in which they will be utilized. Close communication must be established between the research and operational communities so that developers have a complete understanding of user needs. In turn, forecasters must obtain a more comprehensive knowledge of the modeling and sensing tools available to them. A major goal of the SPoRT Program is to develop metrics and conduct assessment studies with NWS forecasters to evaluate the impacts and benefits of ESE experimental products on forecast skill. At a glance the task seems relatively straightforward. However, performing assessment of experimental products in an operational environment is demanding. Given the tremendous time constraints placed on NWS forecasters, it is imperative that forecaster input be obtained in a concise unobtrusive manor. Great care must also be taken to ensure that forecasters understand their participation will eventually benefit them and WFO operations in general. Two requirements of the assessment plan developed under the SPoRT activity are that it 1) Can be implemented within the WFO environment; and 2) Provide tangible results for BOTH the research and operational communities. Supplemental numerical quantitative precipitation forecasts (QPF) were chosen as the first experimental SPoRT product to be evaluated during a Pilot Assessment Program conducted 1 May 2003 within the Huntsville AL National Weather Service Forecast Office. Forecast time periods were broken up into six- hour bins ranging from zero to twenty-four hours. Data were made available for display in AWIPS on an

  16. Driving Performance among Bioptic Telescope Users with Low Vision Two Years after Obtaining Their Driver's License: A Quasi-Experimental Study

    ERIC Educational Resources Information Center

    Vincent, Claude; Lachance, Jean-Paul; Deaudelin, Isabelle

    2012-01-01

    This study sought to compare road safety of new drivers with low vision who have followed a specific pilot bioptic training program with other groups of drivers all matched for age and driving experience. A quasi-experimental design was used two years after drivers obtained their license. Drivers were classified in the experimental group (n = 10,…

  17. Comparison of oxygen saturation values obtained from fingers on physically restrained or unrestrained sides of the body.

    PubMed

    Korhan, Esra Akin; Yönt, Gülendam Hakverdioğlu; Khorshid, Leyla

    2011-01-01

    The aim of this study was to compare semiexperimentally the pulse oximetry values obtained from a finger on restrained or unrestrained sides of the body. The pulse oximeter provides a noninvasive measurement of the oxygen saturation of hemoglobin in arterial blood. One of the procedures most frequently applied to patients in intensive care units is the application of physical restraint. Circulation problems are the most important complication in patients who are physically restrained. Evaluation of oxygen saturation from body parts in which circulation is impeded or has deteriorated can cause false results. The research sample consisted of 30 hospitalized patients who participated in the study voluntarily and who were concordant with the inclusion criteria of the study. Patient information and patient follow-up forms were used for data collection. Pulse oximetry values were measured simultaneously using OxiMax Nellcor finger sensors from fingers on the restrained and unrestrained sides of the body. Numeric and percentile distributions were used in evaluating the sociodemographic properties of patients. A significant difference was found between the oxygen saturation values obtained from a finger of an arm that had been physically restrained and a finger of an arm that had not been physically restrained. The mean oxygen saturation value measured from a finger of an arm that had been physically restrained was found to be 93.40 (SD, 2.97), and the mean oxygen saturation value measured from a finger of an arm that had not been physically restrained was found to be 95.53 (SD, 2.38). The results of this study indicate that nurses should use a finger of an arm that is not physically restrained when evaluating oxygen saturation values to evaluate them correctly.

  18. Comparison of internal dose estimates obtained using organ-level, voxel S value, and Monte Carlo techniques

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grimes, Joshua, E-mail: grimes.joshua@mayo.edu; Celler, Anna

    2014-09-15

    Purpose: The authors’ objective was to compare internal dose estimates obtained using the Organ Level Dose Assessment with Exponential Modeling (OLINDA/EXM) software, the voxel S value technique, and Monte Carlo simulation. Monte Carlo dose estimates were used as the reference standard to assess the impact of patient-specific anatomy on the final dose estimate. Methods: Six patients injected with{sup 99m}Tc-hydrazinonicotinamide-Tyr{sup 3}-octreotide were included in this study. A hybrid planar/SPECT imaging protocol was used to estimate {sup 99m}Tc time-integrated activity coefficients (TIACs) for kidneys, liver, spleen, and tumors. Additionally, TIACs were predicted for {sup 131}I, {sup 177}Lu, and {sup 90}Y assuming themore » same biological half-lives as the {sup 99m}Tc labeled tracer. The TIACs were used as input for OLINDA/EXM for organ-level dose calculation and voxel level dosimetry was performed using the voxel S value method and Monte Carlo simulation. Dose estimates for {sup 99m}Tc, {sup 131}I, {sup 177}Lu, and {sup 90}Y distributions were evaluated by comparing (i) organ-level S values corresponding to each method, (ii) total tumor and organ doses, (iii) differences in right and left kidney doses, and (iv) voxelized dose distributions calculated by Monte Carlo and the voxel S value technique. Results: The S values for all investigated radionuclides used by OLINDA/EXM and the corresponding patient-specific S values calculated by Monte Carlo agreed within 2.3% on average for self-irradiation, and differed by as much as 105% for cross-organ irradiation. Total organ doses calculated by OLINDA/EXM and the voxel S value technique agreed with Monte Carlo results within approximately ±7%. Differences between right and left kidney doses determined by Monte Carlo were as high as 73%. Comparison of the Monte Carlo and voxel S value dose distributions showed that each method produced similar dose volume histograms with a minimum dose covering 90% of the volume

  19. 7 CFR 356.4 - Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Property valued at $10,000 or less; notice of seizure... PROCEDURES § 356.4 Property valued at $10,000 or less; notice of seizure administrative action to obtain... notice of seizure and proposed forfeiture as provided in paragraph (c)(1) of this section, by posting for...

  20. Ignition and Growth Modeling of Detonating LX-04 (85% HMX / 15% VITON) Using New and Previously Obtained Experimental Data

    NASA Astrophysics Data System (ADS)

    Tarver, Craig

    2017-06-01

    An Ignition and Growth reactive flow model for detonating LX-04 (85% HMX / 15% Viton) was developed using new and previously obtained experimental data on: cylinder test expansion; wave curvature; failure diameter; and laser interferometric copper and tantalum foil free surface velocities and LiF interface particle velocity histories. A reaction product JWL EOS generated by the CHEETAH code compared favorably with the existing, well normalized LX-04 product JWL when both were used with the Ignition and Growth model. Good agreement with all existing experimental data was obtained. Keywords: LX-04, HMX, detonation, Ignition and Growth PACS:82.33.Vx, 82.40.Fp This work was performed under the auspices of the U. S. Department of Energy by the Lawrence Livermore National Laboratory under Contract No. DE-AC52-07NA27344.

  1. Statistical evaluation of accelerated stability data obtained at a single temperature. I. Effect of experimental errors in evaluation of stability data obtained.

    PubMed

    Yoshioka, S; Aso, Y; Takeda, Y

    1990-06-01

    Accelerated stability data obtained at a single temperature is statistically evaluated, and the utility of such data for assessment of stability is discussed focussing on the chemical stability of solution-state dosage forms. The probability that the drug content of a product is observed to be within the lower specification limit in the accelerated test is interpreted graphically. This probability depends on experimental errors in the assay and temperature control, as well as the true degradation rate and activation energy. Therefore, the observation that the drug content meets the specification in the accelerated testing can provide only limited information on the shelf-life of the drug, without the knowledge of the activation energy and the accuracy and precision of the assay and temperature control.

  2. Optimization of the parameters for obtaining zirconia-alumina coatings, made by flame spraying from results of numerical simulation

    NASA Astrophysics Data System (ADS)

    Ferrer, M.; Vargas, F.; Peña, G.

    2017-12-01

    The K-Sommerfeld values (K) and the melting percentage (% F) obtained by numerical simulation using the Jets et Poudres software were used to find the projection parameters of zirconia-alumina coatings by thermal spraying flame, in order to obtain coatings with good morphological and structural properties to be used as thermal insulation. The experimental results show the relationship between the Sommerfeld parameter and the porosity of the zirconia-alumina coatings. It is found that the lowest porosity is obtained when the K-Sommerfeld value is close to 45 with an oxidant flame, on the contrary, when superoxidant flames are used K values are close 52, which improve wear resistance.

  3. Steel Fibers Reinforced Concrete Pipes - Experimental Tests and Numerical Simulation

    NASA Astrophysics Data System (ADS)

    Doru, Zdrenghea

    2017-10-01

    The paper presents in the first part a state of the art review of reinforced concrete pipes used in micro tunnelling realised through pipes jacking method and design methods for steel fibres reinforced concrete. In part two experimental tests are presented on inner pipes with diameters of 1410mm and 2200mm, and specimens (100x100x500mm) of reinforced concrete with metal fibres (35 kg / m3). In part two experimental tests are presented on pipes with inner diameters of 1410mm and 2200mm, and specimens (100x100x500mm) of reinforced concrete with steel fibres (35 kg / m3). The results obtained are analysed and are calculated residual flexural tensile strengths which characterise the post-cracking behaviour of steel fibres reinforced concrete. In the third part are presented numerical simulations of the tests of pipes and specimens. The model adopted for the pipes test was a three-dimensional model and loads considered were those obtained in experimental tests at reaching breaking forces. Tensile stresses determined were compared with mean flexural tensile strength. To validate tensile parameters of steel fibres reinforced concrete, experimental tests of the specimens were modelled with MIDAS program to reproduce the flexural breaking behaviour. To simulate post - cracking behaviour was used the method σ — ε based on the relationship stress - strain, according to RILEM TC 162-TDF. For the specimens tested were plotted F — δ diagrams, which have been superimposed for comparison with the similar diagrams of experimental tests. The comparison of experimental results with those obtained from numerical simulation leads to the following conclusions: - the maximum forces obtained by numerical calculation have higher values than the experimental values for the same tensile stresses; - forces corresponding of residual strengths have very similar values between the experimental and numerical calculations; - generally the numerical model estimates a breaking force greater

  4. Simulation and experimental measurement of radon activity using a multichannel silicon-based radiation detector.

    PubMed

    Ozdemir, F B; Selcuk, A B; Ozkorucuklu, S; Alpat, A B; Ozdemir, T; Ӧzek, N

    2018-05-01

    In this study, high-precision radiation detector (HIPRAD), a new-generation semiconductor microstrip detector, was used for detecting radon (Rn-222) activity. The aim of this study was to detect radon (Rn-222) activity experimentally by measuring the energy of particles in this detector. Count-ADC channel, eta-charge, and dose-response values were experimentally obtained using HIPRAD. The radon simulation in the radiation detector was theoretically performed using the Geant4 software package. The obtained radioactive decay, energy generation, energy values, and efficiency values of the simulation were plotted using the root program. The new-generation radiation detector proved to have 95% reliability according to the obtained dose-response graphs. The experimental and simulation results were found to be compatible with each other and with the radon decays and literature studies. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Experimental Surface Pressure Data Obtained on 65 deg Delta Wing Across Reynolds Number and Mach Number Ranges. Volume 1; Sharp Leading Edge; [conducted in the Langley National Transonic Facility (NTF)

    NASA Technical Reports Server (NTRS)

    Chu, Julio; Luckring, James M.

    1996-01-01

    An experimental wind tunnel test of a 65 deg delta wing model with interchangeable leading edges was conducted in the Langley National Transonic Facility (NTF). The objective was to investigate the effects of Reynolds and Mach numbers on slender-wing leading-edge vortex flows with four values of wing leading-edge bluntness. Experimentally obtained pressure data are presented without analysis in tabulated and graphical formats across a Reynolds number range of 6 x 10(exp 6) to 36 x 10(exp 6) at a Mach number of 0.85 and across a Mach number range of 0.4 to 0.9 at a Reynolds number of 6 x 10(exp 6). Normal-force and pitching-moment coefficient plots for these Reynolds number and Mach number ranges are also presented.

  6. Theoretical and experimental prediction of the redox potentials of metallocene compounds

    NASA Astrophysics Data System (ADS)

    Li, Ya-Ping; Liu, Hai-Bo; Liu, Tao; Yu, Zhang-Yu

    2017-11-01

    The standard redox electrode potential ( E°) values of metallocene compounds are obtained theoretically with density functional theory (DFT) method at B3LYP/6-311++G( d, p) level and experimentally with cyclic voltammetry (CV). The theoretical E° values of metallocene compounds are in good agreement with experimental ones. We investigate the substituent effects on the redox properties of metallocene compounds. Among the four metallocene compounds, the E° values is largest for titanocene dichloride and smallest for ferrocene.

  7. Comparison of Theoretical Stresses and Deflections of Multicell Wings with Experimental Results Obtained from Plastic Models

    NASA Technical Reports Server (NTRS)

    Zender, George W

    1956-01-01

    The experimental deflections and stresses of six plastic multicell-wing models of unswept, delta, and swept plan form are presented and compared with previously published theoretical results obtained by the electrical analog method. The comparisons indicate that the theory is reliable except for the evaluation of stresses in the vicinity of the leading edge of delta wings and the leading and trailing edges of swept wings. The stresses in these regions are questionable, apparently because of simplifications employed in idealizing the actual structure for theoretical purposes and because of local effects of concentrated loads.

  8. Modeling functional Magnetic Resonance Imaging (fMRI) experimental variables in the Ontology of Experimental Variables and Values (OoEVV)

    PubMed Central

    Burns, Gully A.P.C.; Turner, Jessica A.

    2015-01-01

    Neuroimaging data is raw material for cognitive neuroscience experiments, leading to scientific knowledge about human neurological and psychological disease, language, perception, attention and ultimately, cognition. The structure of the variables used in the experimental design defines the structure of the data gathered in the experiments; this in turn structures the interpretative assertions that may be presented as experimental conclusions. Representing these assertions and the experimental data which support them in a computable way means that they could be used in logical reasoning environments, i.e. for automated meta-analyses, or linking hypotheses and results across different levels of neuroscientific experiments. Therefore, a crucial first step in being able to represent neuroimaging results in a clear, computable way is to develop representations for the scientific variables involved in neuroimaging experiments. These representations should be expressive, computable, valid, extensible, and easy-to-use. They should also leverage existing semantic standards to interoperate easily with other systems. We present an ontology design pattern called the Ontology of Experimental Variables and Values (OoEVV). This is designed to provide a lightweight framework to capture mathematical properties of data, with appropriate ‘hooks’ to permit linkage to other ontology-driven projects (such as the Ontology of Biomedical Investigations, OBI). We instantiate the OoEVV system with a small number of functional Magnetic Resonance Imaging datasets, to demonstrate the system’s ability to describe the variables of a neuroimaging experiment. OoEVV is designed to be compatible with the XCEDE neuroimaging data standard for data collection terminology, and with the Cognitive Paradigm Ontology (CogPO) for specific reasoning elements of neuroimaging experimental designs. PMID:23684873

  9. Valores, Creencias Y Objectivos: Base del programa de la Escuela Experimental P.K. Yonge. (Values, Beliefs and Objectives: The Basis of Experimental Schools P.K. Yonge's Program.)

    ERIC Educational Resources Information Center

    Florida Univ., Gainesville. Coll. of Education.

    The values, beliefs, and objectives that form the core of the program at the Experimental School P.K. Yonge in the University of Florida are presented in this paper which is written in Spanish. This experimental school serves approximately 900 students from grades one through twelve. The function of the school is to conduct research to solve…

  10. A Dye-Tracer Technique for Experimentally Obtaining Impingement Characteristics of Arbitrary Bodies and a Method for Determining Droplet Size Distribution

    NASA Technical Reports Server (NTRS)

    VonGlahn, Uwe H.; Gelder, Thomas F.; Smyers, William H., Jr.

    1955-01-01

    A dye-tracer technique has been developed whereby the quantity of dyed water collected on a blotter-wrapped body exposed to an air stream containing a dyed-water spray cloud can be colorimetrically determined in order to obtain local collection efficiencies, total collection efficiency, and rearward extent of impingement on the body. In addition, a method has been developed whereby the impingement characteristics obtained experimentally for a body can be related to theoretical impingement data for the same body in order to determine the droplet size distribution of the impinging cloud. Several cylinders, a ribbon, and an aspirating device to measure cloud liquid-water content were used in the studies presented herein for the purpose of evaluating the dye-tracer technique. Although the experimental techniques used in the dye-tracer technique require careful control, the methods presented herein should be applicable for any wind tunnel provided the humidity of the air stream can be maintained near saturation.

  11. 7 CFR 356.4 - Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 5 2012-01-01 2012-01-01 false Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture. 356.4 Section 356.4 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FORFEITURE...

  12. FLUID: A numerical interpolation procedure for obtaining thermodynamic and transport properties of fluids

    NASA Technical Reports Server (NTRS)

    Fessler, T. E.

    1977-01-01

    A computer program subroutine, FLUID, was developed to calculate thermodynamic and transport properties of pure fluid substances. It provides for determining the thermodynamic state from assigned values for temperature-density, pressure-density, temperature-pressure, pressure-entropy, or pressure-enthalpy. Liquid or two-phase (liquid-gas) conditions are considered as well as the gas phase. A van der Waals model is used to obtain approximate state values; these values are then corrected for real gas effects by model-correction factors obtained from tables based on experimental data. Saturation conditions, specific heat, entropy, and enthalpy data are included in the tables for each gas. Since these tables are external to the FLUID subroutine itself, FLUID can implement any gas for which a set of tables has been generated. (A setup phase is used to establish pointers dynamically to the tables for a specific gas.) Data-table preparation is described. FLUID is available in both SFTRAN and FORTRAN

  13. Characterising experimental time series using local intrinsic dimension

    NASA Astrophysics Data System (ADS)

    Buzug, Thorsten M.; von Stamm, Jens; Pfister, Gerd

    1995-02-01

    Experimental strange attractors are analysed with the averaged local intrinsic dimension proposed by A. Passamante et al. [Phys. Rev. A 39 (1989) 3640] which is based on singular value decomposition of local trajectory matrices. The results are compared to the values of Kaplan-Yorke and the correlation dimension. The attractors, reconstructed with Takens' delay time coordinates from scalar velocity time series, are measured in the hydrodynamic Taylor-Couette system. A period doubling route towards chaos obtained from a very short Taylor-Couette cylinder yields a sequence of experimental time series where the local intrinsic dimension is applied.

  14. An accurate density functional theory based estimation of pK(a) values of polar residues combined with experimental data: from amino acids to minimal proteins.

    PubMed

    Matsui, Toru; Baba, Takeshi; Kamiya, Katsumasa; Shigeta, Yasuteru

    2012-03-28

    We report a scheme for estimating the acid dissociation constant (pK(a)) based on quantum-chemical calculations combined with a polarizable continuum model, where a parameter is determined for small reference molecules. We calculated the pK(a) values of variously sized molecules ranging from an amino acid to a protein consisting of 300 atoms. This scheme enabled us to derive a semiquantitative pK(a) value of specific chemical groups and discuss the influence of the surroundings on the pK(a) values. As applications, we have derived the pK(a) value of the side chain of an amino acid and almost reproduced the experimental value. By using our computing schemes, we showed the influence of hydrogen bonds on the pK(a) values in the case of tripeptides, which decreases the pK(a) value by 3.0 units for serine in comparison with those of the corresponding monopeptides. Finally, with some assumptions, we derived the pK(a) values of tyrosines and serines in chignolin and a tryptophan cage. We obtained quite different pK(a) values of adjacent serines in the tryptophan cage; the pK(a) value of the OH group of Ser13 exposed to bulk water is 14.69, whereas that of Ser14 not exposed to bulk water is 20.80 because of the internal hydrogen bonds.

  15. Experimental study of low-energy charge transfer in nitrogen

    NASA Technical Reports Server (NTRS)

    Smith, A.

    1979-01-01

    Total charge transfer cross sections were obtained for the N2(+)-N2 system with relative translational ion energies between 9 and 441 eV. Data were obtained to examine the dependence of total cross section on ion energy. The effect of ion excitation on the cross sections was studied by varying the electron ionization energy in the mass spectrometer ion source over an electron energy range between 14.5 and 32.1 eV. The dependence of total cross section on the neutralization chamber gas pressure was examined by obtaining data at pressure values from 9.9 to 0.000199 torr. Cross section values obtained were compared with experimental and theoretical results of other investigations.

  16. Fundamental period of Italian reinforced concrete buildings: comparison between numerical, experimental and Italian code simplified values

    NASA Astrophysics Data System (ADS)

    Ditommaso, Rocco; Carlo Ponzo, Felice; Auletta, Gianluca; Iacovino, Chiara; Nigro, Antonella

    2015-04-01

    Aim of this study is a comparison among the fundamental period of reinforced concrete buildings evaluated using the simplified approach proposed by the Italian Seismic code (NTC 2008), numerical models and real values retrieved from an experimental campaign performed on several buildings located in Basilicata region (Italy). With the intention of proposing simplified relationships to evaluate the fundamental period of reinforced concrete buildings, scientists and engineers performed several numerical and experimental campaigns, on different structures all around the world, to calibrate different kind of formulas. Most of formulas retrieved from both numerical and experimental analyses provides vibration periods smaller than those suggested by the Italian seismic code. However, it is well known that the fundamental period of a structure play a key role in the correct evaluation of the spectral acceleration for seismic static analyses. Generally, simplified approaches impose the use of safety factors greater than those related to in depth nonlinear analyses with the aim to cover possible unexpected uncertainties. Using the simplified formula proposed by the Italian seismic code the fundamental period is quite higher than fundamental periods experimentally evaluated on real structures, with the consequence that the spectral acceleration adopted in the seismic static analysis may be significantly different than real spectral acceleration. This approach could produces a decreasing in safety factors obtained using linear and nonlinear seismic static analyses. Finally, the authors suggest a possible update of the Italian seismic code formula for the simplified estimation of the fundamental period of vibration of existing RC buildings, taking into account both elastic and inelastic structural behaviour and the interaction between structural and non-structural elements. Acknowledgements This study was partially funded by the Italian Civil Protection Department within the

  17. Comparison of Water-Load Distributions Obtained during Seaplane Landings with Bureau of Aeronautics Specifications. TED No. NACA 2413

    NASA Technical Reports Server (NTRS)

    Smiley, Robert F.; Haines, Gilbert A.

    1949-01-01

    Bureau of Aeronautics Design Specifications SS-IC-2 for water loads in sheltered water are compared with experimental water loads obtained during a full--scale landing investigation. This investigation was conducted with a JRS-1 flying boat which has a 20 degrees dead-rise V-bottom with a partial chine flare. The range of landing conditions included airspeeds between 88 and 126 feet per second, sinking speeds between 1.6 and 9.1 feet per second, flight angles less than 6 degrees, and trims between 2 degrees and 12 degrees. Landings were moderate and were made in calm water. Measurements were obtained of maximum over-all loads, maximum pitching moments, and pressure distributions. Maximum experimental loads include over-all load factors of 2g, moments of 128,000 pound-feet, and maximum local pressures greater than 40 pounds per square inch. Experimental over-all loads are approximately one-half the design values, while local pressures are of the same order as or larger than pressures calculated from specifications for plating, stringer, floor, and frame design. The value of this comparison is limited, to some extent, by the moderate conditions of the test and by the necessary simplifying assumptions used in comparing the specifications with the experimental loads.

  18. Utilization of coffee by-products obtained from semi-washed process for production of value-added compounds.

    PubMed

    Bonilla-Hermosa, Verónica Alejandra; Duarte, Whasley Ferreira; Schwan, Rosane Freitas

    2014-08-01

    The semi-dry processing of coffee generates significant amounts of coffee pulp and wastewater. This study evaluated the production of bioethanol and volatile compounds of eight yeast strains cultivated in a mixture of these residues. Hanseniaspora uvarum UFLA CAF76 showed the best fermentation performance; hence it was selected to evaluate different culture medium compositions and inoculum size. The best results were obtained with 12% w/v of coffee pulp, 1 g/L of yeast extract and 0.3 g/L of inoculum. Using these conditions, fermentation in 1 L of medium was carried out, achieving higher ethanol yield, productivity and efficiency with values of 0.48 g/g, 0.55 g/L h and 94.11% respectively. Twenty-one volatile compounds corresponding to higher alcohols, acetates, terpenes, aldehydes and volatile acids were identified by GC-FID. Such results indicate that coffee residues show an excellent potential as substrates for production of value-added compounds. H. uvarum demonstrated high fermentative capacity using these residues. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. An Experimental and Theoretical Study of Nitrogen-Broadened Acetylene Lines

    NASA Technical Reports Server (NTRS)

    Thibault, Franck; Martinez, Raul Z.; Bermejo, Dionisio; Ivanov, Sergey V.; Buzykin, Oleg G.; Ma, Qiancheng

    2014-01-01

    We present experimental nitrogen-broadening coefficients derived from Voigt profiles of isotropic Raman Q-lines measured in the 2 band of acetylene (C2H2) at 150 K and 298 K, and compare them to theoretical values obtained through calculations that were carried out specifically for this work. Namely, full classical calculations based on Gordon's approach, two kinds of semi-classical calculations based on Robert Bonamy method as well as full quantum dynamical calculations were performed. All the computations employed exactly the same ab initio potential energy surface for the C2H2N2 system which is, to our knowledge, the most realistic, accurate and up-to-date one. The resulting calculated collisional half-widths are in good agreement with the experimental ones only for the full classical and quantum dynamical methods. In addition, we have performed similar calculations for IR absorption lines and compared the results to bibliographic values. Results obtained with the full classical method are again in good agreement with the available room temperature experimental data. The quantum dynamical close-coupling calculations are too time consuming to provide a complete set of values and therefore have been performed only for the R(0) line of C2H2. The broadening coefficient obtained for this line at 173 K and 297 K also compares quite well with the available experimental data. The traditional Robert Bonamy semi-classical formalism, however, strongly overestimates the values of half-width for both Qand R-lines. The refined semi-classical Robert Bonamy method, first proposed for the calculations of pressure broadening coefficients of isotropic Raman lines, is also used for IR lines. By using this improved model that takes into account effects from line coupling, the calculated semi-classical widths are significantly reduced and closer to the measured ones.

  20. 7 CFR 356.3 - Property valued at greater than $10,000; notice of seizure and civil action to obtain forfeiture.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 5 2012-01-01 2012-01-01 false Property valued at greater than $10,000; notice of seizure and civil action to obtain forfeiture. 356.3 Section 356.3 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  1. Analysis on Experimental Investigation and Mathematical Modeling of Incompressible Flow Through Ceramic Foam Filters

    NASA Astrophysics Data System (ADS)

    Akbarnejad, Shahin; Jonsson, Lage Tord Ingemar; Kennedy, Mark William; Aune, Ragnhild Elizabeth; Jönsson, Pӓr Göran

    2016-08-01

    This paper presents experimental results of pressure drop measurements on 30, 50, and 80 pores per inch (PPI) commercial alumina ceramic foam filters (CFF) and compares the obtained pressure drop profiles to numerically modeled values. In addition, it is aimed at investigating the adequacy of the mathematical correlations used in the analytical and the computational fluid dynamics (CFD) simulations. It is shown that the widely used correlations for predicting pressure drop in porous media continuously under-predict the experimentally obtained pressure drop profiles. For analytical predictions, the negative deviations from the experimentally obtained pressure drop using the unmodified Ergun and Dietrich equations could be as high as 95 and 74 pct, respectively. For the CFD predictions, the deviation to experimental results is in the range of 84.3 to 88.5 pct depending on filter PPI. Better results can be achieved by applying the Forchheimer second-order drag term instead of the Brinkman-Forchheimer drag term. Thus, the final deviation of the CFD model estimates lie in the range of 0.3 to 5.5 pct compared to the measured values.

  2. Discussion about the use of the volume specific surface area (VSSA) as a criterion to identify nanomaterials according to the EU definition. Part two: experimental approach.

    PubMed

    Lecloux, André J; Atluri, Rambabu; Kolen'ko, Yury V; Deepak, Francis Leonard

    2017-10-12

    The first part of this study was dedicated to the modelling of the influence of particle shape, porosity and particle size distribution on the volume specific surface area (VSSA) values in order to check the applicability of this concept to the identification of nanomaterials according to the European Commission Recommendation. In this second part, experimental VSSA values are obtained for various samples from nitrogen adsorption isotherms and these values were used as a screening tool to identify and classify nanomaterials. These identification results are compared to the identification based on the 50% of particles with a size below 100 nm criterion applied to the experimental particle size distributions obtained by analysis of electron microscopy images on the same materials. It is concluded that the experimental VSSA values are able to identify nanomaterials, without false negative identification, if they have a mono-modal particle size, if the adsorption data cover the relative pressure range from 0.001 to 0.65 and if a simple, qualitative image of the particles by transmission or scanning electron microscopy is available to define their shape. The experimental conditions to obtain reliable adsorption data as well as the way to analyze the adsorption isotherms are described and discussed in some detail in order to help the reader in using the experimental VSSA criterion. To obtain the experimental VSSA values, the BET surface area can be used for non-porous particles, but for porous, nanostructured or coated nanoparticles, only the external surface of the particles, obtained by a modified t-plot approach, should be considered to determine the experimental VSSA and to avoid false positive identification of nanomaterials, only the external surface area being related to the particle size. Finally, the availability of experimental VSSA values together with particle size distributions obtained by electron microscopy gave the opportunity to check the

  3. The Defense Logistics Agency Properly Awarded Power Purchase Agreements and the Army Obtained Fair Market Value for Leases Supporting Power Purchase Agreements

    DTIC Science & Technology

    2016-09-28

    Fair Market Value for Leases Supporting Power Purchase Agreements I N T E G R I T Y  E F F I C I E N C Y  A C C O U N T A B I L I T Y  E X... Market Value for Leases Supporting Power Purchase Agreements Visit us at www.dodig.mil September 28, 2016 Objective We determined whether the...Department of the Army properly awarded and obtained fair market value for leases supporting energy production projects. We conducted this audit in

  4. Experimental and predicted cavitation performance of an 80.6 deg helical inducer in high temperature water

    NASA Technical Reports Server (NTRS)

    Kovich, G.

    1972-01-01

    The cavitating performance of a stainless steel 80.6 degree flat-plate helical inducer was investigated in water over a range of liquid temperatures and flow coefficients. A semi-empirical prediction method was used to compare predicted values of required net positive suction head in water with experimental values obtained in water. Good agreement was obtained between predicted and experimental data in water. The required net positive suction head in water decreased with increasing temperature and increased with flow coefficient, similar to that observed for a like inducer in liquid hydrogen.

  5. UV index experimental values during the years 2000 and 2001 from the Spanish broadband UV-B radiometric network.

    PubMed

    Martínez-Lozano, José A; Marín, María J; Tena, Fernando; Utrillas, María P; Sánchez-Muniosguren, Luis; González-Frías, Carlos; Cuevas, Emilio; Redondas, Alberto; Lorente, Jerónimo; de Cabo, Xavier; Cachorro, Victoria; Vergaz, Ricardo; de Frutos, Angel; Díaz, Juan P; Expósito, Francisco J; de la Morena, Benito; Vilaplana, José M

    2002-08-01

    An analysis is made of experimental ultraviolet erythemal solar radiation data measured during the years 2000 and 2001 by the Spanish UV-B radiation evaluation and prediction network. This network consists of 16 Robertson-Berger type pyranometers for evaluating solar erythemal radiation and five Brewer spectroradiometers for evaluating the stratospheric ozone. On the basis of these data the Ultraviolet Index (UVI) was evaluated for the measuring stations that are located either in coastal regions or in the more densely populated regions inland on the Iberian Peninsula. It has been checked that in most cases the maximum irradiance values corresponded to solar noon, although there were exceptions that could be explained by cloudiness. The maximum experimental values of the UVI were around 9 during the summer, though frequently passing this value at the inland measurement stations. The annual accumulated dose of irradiation on a horizontal plane has also been studied, as well as the evolution through the year in units of energy, standard erythemal doses and minimum erythemal doses, according to different phototypes.

  6. Experimental validation of beam quality correction factors for proton beams

    NASA Astrophysics Data System (ADS)

    Gomà, Carles; Hofstetter-Boillat, Bénédicte; Safai, Sairos; Vörös, Sándor

    2015-04-01

    This paper presents a method to experimentally validate the beam quality correction factors (kQ) tabulated in IAEA TRS-398 for proton beams and to determine the kQ of non-tabulated ionization chambers (based on the already tabulated values). The method is based exclusively on ionometry and it consists in comparing the reading of two ionization chambers under the same reference conditions in a proton beam quality Q and a reference beam quality 60Co. This allows one to experimentally determine the ratio between the kQ of the two ionization chambers. In this work, 7 different ionization chamber models were irradiated under the IAEA TRS-398 reference conditions for 60Co beams and proton beams. For the latter, the reference conditions for both modulated beams (spread-out Bragg peak field) and monoenergetic beams (pseudo-monoenergetic field) were studied. For monoenergetic beams, it was found that the experimental kQ values obtained for plane-parallel chambers are consistent with the values tabulated in IAEA TRS-398; whereas the kQ values obtained for cylindrical chambers are not consistent—being higher than the tabulated values. These results support the suggestion (of previous publications) that the IAEA TRS-398 reference conditions for monoenergetic proton beams should be revised so that the effective point of measurement of cylindrical ionization chambers is taken into account when positioning the reference point of the chamber at the reference depth. For modulated proton beams, the tabulated kQ values of all the ionization chambers studied in this work were found to be consistent with each other—except for the IBA FC65-G, whose experimental kQ value was found to be 0.6% lower than the tabulated one. The kQ of the PTW Advanced Markus chamber, which is not tabulated in IAEA TRS-398, was found to be 0.997 ± 0.042 (k = 2), based on the tabulated value of the PTW Markus chamber.

  7. Comparison of Monte Carlo simulation of gamma ray attenuation coefficients of amino acids with XCOM program and experimental data

    NASA Astrophysics Data System (ADS)

    Elbashir, B. O.; Dong, M. G.; Sayyed, M. I.; Issa, Shams A. M.; Matori, K. A.; Zaid, M. H. M.

    2018-06-01

    The mass attenuation coefficients (μ/ρ), effective atomic numbers (Zeff) and electron densities (Ne) of some amino acids obtained experimentally by the other researchers have been calculated using MCNP5 simulations in the energy range 0.122-1.330 MeV. The simulated values of μ/ρ, Zeff, and Ne were compared with the previous experimental work for the amino acids samples and a good agreement was noticed. Moreover, the values of mean free path (MFP) for the samples were calculated using MCNP5 program and compared with the theoretical results obtained by XCOM. The investigation of μ/ρ, Zeff, Ne and MFP values of amino acids using MCNP5 simulations at various photon energies when compared with the XCOM values and previous experimental data for the amino acids samples revealed that MCNP5 code provides accurate photon interaction parameters for amino acids.

  8. Experimental Results Obtained with Air Liquide Cold Compression System: CERN LHC and SNS Projects

    NASA Astrophysics Data System (ADS)

    Delcayre, F.; Courty, J.-C.; Hamber, F.; Hilbert, B.; Monneret, E.; Toia, J.-L.

    2006-04-01

    Large scale collider facilities will make intensive use of superconducting magnets, operating below 2.0 K. This dictates high-capacity refrigeration systems operating below 2.0 K. These systems, making use of cryogenic centrifugal compressors in a series arrangement with room temperature screw compressors will be coupled to a refrigerator, providing a certain power at 4.5 K. A first Air Liquide Cold Compression System (CCS) unit was built and delivered to CERN in 2001. Installed at the beginning of 2002, it was commissioned and tested successfully during year 2002. A series of four sets of identical CCS were then tested in 2004. Another set of four cryogenic centrifugal compressors (CCC) has been delivered to Thomas Jefferson National Accelerator Facility (JLAB) for the Spallation Neutron Source (SNS) in 2002. These compressors were tested and commissioned from December 2004 to July 2005. The experimental results obtained with these systems will be presented and discussed: the characteristics of the CCC will be detailed. The principles of control for the CCC in series will be detailed.

  9. Experimental trim drag values for conventional and supercritical wings. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Jacobs, P. F.

    1981-01-01

    Supercritical wings were studied to determine whether they incur higher trim drag values at cruise conditions than wide body technology wings. Relative trim drag increments were measured in an experimental wind tunnel investigation. The tests utilized high aspect ratio supercritical wing and a wide body wing in conjunction with five different horizontal tail configurations, mounted on a representative wide body fuselage. The three low tail configurations and two T tail configurations were chosen to measure the effects on horizontal tail size, location, and camber on the trim drag increments for the two wings. The increase in performance (lift to drag ratio) for supercritical wing over the wide body wing was 11 percent for both the optimum low tail and T tail configurations.

  10. Experimental Evaluation of the Value Added by Raising a Reader and Supplemental Parent Training in Shared Reading

    ERIC Educational Resources Information Center

    Anthony, Jason L.; Williams, Jeffrey M.; Zhang, Zhoe; Landry, Susan H.; Dunkelberger, Martha J.

    2014-01-01

    Research Findings: In an effort toward developing a comprehensive, effective, scalable, and sustainable early childhood education program for at-risk populations, we conducted an experimental evaluation of the value added by 2 family involvement programs to the Texas Early Education Model (TEEM). A total of 91 preschool classrooms that served…

  11. An iterative transformation procedure for numerical solution of flutter and similar characteristics-value problems

    NASA Technical Reports Server (NTRS)

    Gossard, Myron L

    1952-01-01

    An iterative transformation procedure suggested by H. Wielandt for numerical solution of flutter and similar characteristic-value problems is presented. Application of this procedure to ordinary natural-vibration problems and to flutter problems is shown by numerical examples. Comparisons of computed results with experimental values and with results obtained by other methods of analysis are made.

  12. Ethical issues in field research: balancing competing values.

    PubMed

    O'Neill, P

    1990-04-01

    An ethical issue becomes a dilemma when the psychologist is pulled in different directions by competing values. This paper will focus on the conflict between experimental and ethical values inherent in field research. The problem has special significance in community psychology, which gives priority to studying, in natural settings, those affected by social problems. An example is given of research that required observation of family interaction in the homes of convicted child abusers. The case demonstrates that the value of ecological validity often conflicts with the need to protect privacy and obtain uncoerced consent. Other ethical constraints, including the duty to report lawbreaking and to protect the public from harm, may threaten research validity.

  13. Experimental investigation of heat transfer and effectiveness in corrugated plate heat exchangers having different chevron angles

    NASA Astrophysics Data System (ADS)

    Kılıç, Bayram; İpek, Osman

    2017-02-01

    In this study, heat transfer rate and effectiveness of corrugated plate heat exchangers having different chevron angles were investigated experimentally. Chevron angles of plate heat exchangers are β = 30° and β = 60°. For this purpose, experimentally heating system used plate heat exchanger was designed and constructed. Thermodynamic analysis of corrugated plate heat exchangers having different chevron angles were carried out. The heat transfer rate and effectiveness values are calculated. The experimental results are shown that heat transfer rate and effectiveness values for β = 60° is higher than that of the other. Obtained experimental results were graphically presented.

  14. Remote measurement of water color in coastal waters. [spectral radiance data used to obtain quantitative values for chlorophyll and turbidity

    NASA Technical Reports Server (NTRS)

    Weldon, J. W.

    1973-01-01

    An investigation was conducted to develop procedure to obtain quantitative values for chlorophyll and turbidity in coastal waters by observing the changes in spectral radiance of the backscattered spectrum. The technique under consideration consists of Examining Exotech model 20-D spectral radiometer data and determining which radiance ratios best correlated with chlorophyll and turbidity measurements as obtained from analyses of water samples and sechi visibility readings. Preliminary results indicate that there is a correlation between backscattered light and chlorophyll concentration and secchi visibility. The tests were conducted with the spectrometer mounted in a light aircraft over the Mississippi Sound at altitudes of 2.5K, 2.8K and 10K feet.

  15. True detection limits in an experimental linearly heteroscedastic system.. Part 2

    NASA Astrophysics Data System (ADS)

    Voigtman, Edward; Abraham, Kevin T.

    2011-11-01

    Despite much different processing of the experimental fluorescence detection data presented in Part 1, essentially the same estimates were obtained for the true theoretical Currie decision levels ( YC and XC) and true Currie detection limits ( YD and XD). The obtained experimental values, for 5% probability of false positives and 5% probability of false negatives, were YC = 56.0 mV, YD = 125. mV, XC = 0.132 μg/mL and XD = 0.293 μg/mL. For 5% probability of false positives and 1% probability of false negatives, the obtained detection limits were YD = 158 . mV and XD = 0.371 μg/mL. Furthermore, by using bootstrapping methodology on the experimental data for the standards and the analytical blank, it was possible to validate previously published experimental domain expressions for the decision levels ( yC and xC) and detection limits ( yD and xD). This was demonstrated by testing the generated decision levels and detection limits for their performance in regard to false positives and false negatives. In every case, the obtained numbers of false negatives and false positives were as specified a priori.

  16. The Search for Significance: A Few Peculiarities in the Distribution of P Values in Experimental Psychology Literature.

    PubMed

    Krawczyk, Michał

    2015-01-01

    In this project I investigate the use and possible misuse of p values in papers published in five (high-ranked) journals in experimental psychology. I use a data set of over 135'000 p values from more than five thousand papers. I inspect (1) the way in which the p values are reported and (2) their distribution. The main findings are following: first, it appears that some authors choose the mode of reporting their results in an arbitrary way. Moreover, they often end up doing it in such a way that makes their findings seem more statistically significant than they really are (which is well known to improve the chances for publication). Specifically, they frequently report p values "just above" significance thresholds directly, whereas other values are reported by means of inequalities (e.g. "p<.1"), they round the p values down more eagerly than up and appear to choose between the significance thresholds and between one- and two-sided tests only after seeing the data. Further, about 9.2% of reported p values are inconsistent with their underlying statistics (e.g. F or t) and it appears that there are "too many" "just significant" values. One interpretation of this is that researchers tend to choose the model or include/discard observations to bring the p value to the right side of the threshold.

  17. Partition coefficients of methylated DNA bases obtained from free energy calculations with molecular electron density derived atomic charges.

    PubMed

    Lara, A; Riquelme, M; Vöhringer-Martinez, E

    2018-05-11

    Partition coefficients serve in various areas as pharmacology and environmental sciences to predict the hydrophobicity of different substances. Recently, they have also been used to address the accuracy of force fields for various organic compounds and specifically the methylated DNA bases. In this study, atomic charges were derived by different partitioning methods (Hirshfeld and Minimal Basis Iterative Stockholder) directly from the electron density obtained by electronic structure calculations in a vacuum, with an implicit solvation model or with explicit solvation taking the dynamics of the solute and the solvent into account. To test the ability of these charges to describe electrostatic interactions in force fields for condensed phases, the original atomic charges of the AMBER99 force field were replaced with the new atomic charges and combined with different solvent models to obtain the hydration and chloroform solvation free energies by molecular dynamics simulations. Chloroform-water partition coefficients derived from the obtained free energies were compared to experimental and previously reported values obtained with the GAFF or the AMBER-99 force field. The results show that good agreement with experimental data is obtained when the polarization of the electron density by the solvent has been taken into account, and when the energy needed to polarize the electron density of the solute has been considered in the transfer free energy. These results were further confirmed by hydration free energies of polar and aromatic amino acid side chain analogs. Comparison of the two partitioning methods, Hirshfeld-I and Minimal Basis Iterative Stockholder (MBIS), revealed some deficiencies in the Hirshfeld-I method related to the unstable isolated anionic nitrogen pro-atom used in the method. Hydration free energies and partitioning coefficients obtained with atomic charges from the MBIS partitioning method accounting for polarization by the implicit solvation model

  18. Experimental study of a variable-capacitance micromotor with electrostatic suspension

    NASA Astrophysics Data System (ADS)

    Han, F. T.; Wu, Q. P.; Wang, L.

    2010-11-01

    A variable-capacitance micromotor where the rotor is supported electrostatically in five degrees of freedom was designed, fabricated and tested in order to study the behavior of this electrostatic motor. The micromachined device is based on a glass/silicon/glass stack bonding structure, fabricated by bulk micromachining and initially operated in atmospheric environment. The analytical torque model is obtained by calculating the capacitances between different stator electrodes and the rotor. Capacitance values in the order of 10-13 pF and torque values in the order of 10-10 N m have been calculated from the motor geometry and attainable drive voltage. A dynamic model of the motor is proposed by further estimating the air-film damping effect in an effort to explain the experimental rotation measurements. Experimental results of starting voltage, continuous operation, switching response and electric bearing of the micromotor are presented and discussed. Preliminary measurements indicate that a rotor rotating speed of 73.3 r min-1 can be achieved at a drive voltage of 28.3 V, equivalent to a theoretical motive torque of 517 pN m. Starting voltage results obtained from experimental measurement are in agreement with the developed dynamic model.

  19. Binding energies from diffusion Monte Carlo for the MB-pol H{sub 2}O and D{sub 2}O dimer: A comparison to experimental values

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mallory, Joel D.; Mandelshtam, Vladimir A.

    2015-10-14

    The diffusion Monte Carlo (DMC) method is applied to compute the ground state energies of the water monomer and dimer and their D{sub 2}O isotopomers using MB-pol; the most recent and most accurate ab inito-based potential energy surface (PES). MB-pol has already demonstrated excellent agreement with high level electronic structure data, as well as agreement with some experimental, spectroscopic, and thermodynamic data. Here, the DMC binding energies of (H{sub 2}O){sub 2} and (D{sub 2}O){sub 2} agree with the corresponding values obtained from velocity map imaging within, respectively, 0.01 and 0.02 kcal/mol. This work adds two more valuable data points thatmore » highlight the accuracy of the MB-pol PES.« less

  20. Unsteady Ejector Performance: an Experimental Investigation Using a Pulsejet Driver

    NASA Technical Reports Server (NTRS)

    Paxson, Daniel E.; Wilson, Jack; Dougherty, Kevin T.

    2002-01-01

    An experimental investigation is described in which thrust augmentation and mass entrainment were measured for a variety of simple cylindrical ejectors driven by a gasoline-fueled pulsejet. The ejectors were of varying length, diameter, and inlet radius. Measurements were also taken to determine the effect on performance of the distance between pulsejet exit and ejector inlet. Limited tests were also conducted to determine the effect of driver cross-sectional shape. Optimal values were found for all three ejector parameters with respect to thrust augmentation. This was not the case with mass entrainment, which increased monotonically with ejector diameter. Thus, it was found that thrust augmentation is not necessarily directly related to mass entrainment, as is often supposed for ejectors. Peak thrust augmentation values of 1.8 were obtained. Peak mass entrainment values of 30 times the driver mass flow were also observed. Details of the experimental setup and results are presented. Preliminary analysis of the results indicates that the enhanced performance obtained with an unsteady jet (primary source) over comparably sized ejectors driven with steady jets is due primarily to the structure of the starting vortex-type flow associated with the former.

  1. Proximate analyses and predicting HHV of chars obtained from cocracking of petroleum vacuum residue with coal, plastics and biomass.

    PubMed

    Ahmaruzzaman, M

    2008-07-01

    Higher heating value (HHV) and analysis of chars obtained from cocracking of petroleum vacuum residue (XVR) with coal (SC), biomass (BG, CL) and plastics (PP, PS, BL) are important which define the energy content and determine the clean and efficient use of these chars. The main aim of the present study is to analyze the char obtained from cocracking in terms of their proximate analysis data and determination of the HHV of the chars. The char obtained from XVR+PP cocracking showed a HHV of 32.84 MJ/kg, whereas that from CL cracking showed a HHV of 18.52 MJ/kg. The experimentally determined heating values of the char samples obtained from cocracking have been correlated with the theoretical equation based on proximate analysis data. There exists a variety of correlations for predicting HHV from proximate analysis of fuels. Based upon proximate analysis data, the models were tested. The best results show coefficient of determination (R2) of 0.965 and average absolute and bias error of 3.07% and 0.41%, respectively. The heating values obtained from the model were in good agreement with that obtained by experiment. Proximate analysis of the chars obtained from the cocracking of XVR with coal, biomass and plastics showed that there exists a definite interaction of the reactive species, when they were cocracked together.

  2. Thermoelectric generator based on composites obtained by sintering of detonation nanodiamonds

    NASA Astrophysics Data System (ADS)

    Eidelman, E. D.; Meilakhs, A. P.; Semak, B. V.; Shakhov, F. M.

    2017-11-01

    A model of a thermoelectric generator is proposed, in which composite materials obtained by sintering diamond nanoparticles are used as the main component. To increase the useful conversion of heat into electric current, it is proposed to use the effect of electron drag by ballistic phonons. To reduce the ineffective heat spread, it is proposed to use the effect of thermal resistance of the boundaries between the graphite-like and diamond-like phases of the composite. An experimental confirmation of the existence of an optimal volume ratio between graphite-like and diamond-like phases of the composite is predicted and obtained. The highest achieved value of thermoelectric coefficient in the actual structure is 80 µV K-1 (which means 20 times increase compared to that of composites not of the optimal structure), with a thermal conductivity of 50 W m-1 K-1. These results were obtained with constant electrical conductivity. The combined influence of these two effects in case of the ideal composite structure should result in an increase of the thermoelectric efficiency parameter by three orders of magnitude.

  3. The Search for Significance: A Few Peculiarities in the Distribution of P Values in Experimental Psychology Literature

    PubMed Central

    Krawczyk, Michał

    2015-01-01

    In this project I investigate the use and possible misuse of p values in papers published in five (high-ranked) journals in experimental psychology. I use a data set of over 135’000 p values from more than five thousand papers. I inspect (1) the way in which the p values are reported and (2) their distribution. The main findings are following: first, it appears that some authors choose the mode of reporting their results in an arbitrary way. Moreover, they often end up doing it in such a way that makes their findings seem more statistically significant than they really are (which is well known to improve the chances for publication). Specifically, they frequently report p values “just above” significance thresholds directly, whereas other values are reported by means of inequalities (e.g. “p<.1”), they round the p values down more eagerly than up and appear to choose between the significance thresholds and between one- and two-sided tests only after seeing the data. Further, about 9.2% of reported p values are inconsistent with their underlying statistics (e.g. F or t) and it appears that there are “too many” “just significant” values. One interpretation of this is that researchers tend to choose the model or include/discard observations to bring the p value to the right side of the threshold. PMID:26061881

  4. The experimental and calculated characteristics of 22 tapered wings

    NASA Technical Reports Server (NTRS)

    Anderson, Raymond F

    1938-01-01

    The experimental and calculated aerodynamic characteristics of 22 tapered wings are compared, using tests made in the variable-density wind tunnel. The wings had aspect ratios from 6 to 12 and taper ratios from 1:6:1 and 5:1. The compared characteristics are the pitching moment, the aerodynamic-center position, the lift-curve slope, the maximum lift coefficient, and the curves of drag. The method of obtaining the calculated values is based on the use of wing theory and experimentally determined airfoil section data. In general, the experimental and calculated characteristics are in sufficiently good agreement that the method may be applied to many problems of airplane design.

  5. Gaseous Sulfate Solubility in Glass: Experimental Method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bliss, Mary

    2013-11-30

    Sulfate solubility in glass is a key parameter in many commercial glasses and nuclear waste glasses. This report summarizes key publications specific to sulfate solubility experimental methods and the underlying physical chemistry calculations. The published methods and experimental data are used to verify the calculations in this report and are expanded to a range of current technical interest. The calculations and experimental methods described in this report will guide several experiments on sulfate solubility and saturation for the Hanford Waste Treatment Plant Enhanced Waste Glass Models effort. There are several tables of sulfate gas equilibrium values at high temperature tomore » guide experimental gas mixing and to achieve desired SO3 levels. This report also describes the necessary equipment and best practices to perform sulfate saturation experiments for molten glasses. Results and findings will be published when experimental work is finished and this report is validated from the data obtained.« less

  6. Analysis of Experimental Sea-level Transient Data and Analog Method of Obtaining Altitude Response for Turbine-propeller Engine with Relay-type Speed Control

    NASA Technical Reports Server (NTRS)

    Vasu, George; Pack, George J

    1951-01-01

    Correlation has been established between transient engine and control data obtained experimentally and data obtained by simulating the engine and control with an analog computer. This correlation was established at sea-level conditions for a turbine-propeller engine with a relay-type speed control. The behavior of the controlled engine at altitudes of 20,000 and 35,000 feet was determined with an analog computer using the altitude pressure and temperature generalization factors to calculate the new engine constants for these altitudes. Because the engine response varies considerably at altitude some type of compensation appears desirable and four methods of compensation are discussed.

  7. A comparison of the calculated and experimental off-design performance of a radial flow turbine

    NASA Technical Reports Server (NTRS)

    Tirres, Lizet

    1992-01-01

    Off design aerodynamic performance of the solid version of a cooled radial inflow turbine is analyzed. Rotor surface static pressure data and other performance parameters were obtained experimentally. Overall stage performance and turbine blade surface static to inlet total pressure ratios were calculated by using a quasi-three dimensional inviscid code. The off design prediction capability of this code for radial inflow turbines shows accurate static pressure prediction. Solutions show a difference of 3 to 5 points between the experimentally obtained efficiencies and the calculated values.

  8. A comparison of the calculated and experimental off-design performance of a radial flow turbine

    NASA Technical Reports Server (NTRS)

    Tirres, Lizet

    1991-01-01

    Off design aerodynamic performance of the solid version of a cooled radial inflow turbine is analyzed. Rotor surface static pressure data and other performance parameters were obtained experimentally. Overall stage performance and turbine blade surface static to inlet total pressure ratios were calculated by using a quasi-three dimensional inviscid code. The off design prediction capability of this code for radial inflow turbines shows accurate static pressure prediction. Solutions show a difference of 3 to 5 points between the experimentally obtained efficiencies and the calculated values.

  9. Obtaining value prior to pulping with diethyl oxalate and oxalic acid

    Treesearch

    W.R. Kenealy; E. Horn; C.J. Houtman; J. Laplaza; T.W. Jeffries

    2007-01-01

    Pulp and paper are converted to paper products with yields of paper dependent on the wood and the process used. Even with high yield pulps there are conversion losses and with chemical pulps the yields approach 50%. The portions of the wood that do not provide product are either combusted to generate power and steam or incur a cost in waste water treatment. Value prior...

  10. Appraisal on the wound healing activity of different extracts obtained from Aegle marmelos and Mucuna pruriens by in vivo experimental models.

    PubMed

    Toppo, F A; Pawar, R S

    2016-01-01

    The use of a simple and reproducible model is inevitable for an objective statement of the effects of external factors on wound healing. Hence, the present study was conducted to evaluate wound healing activities of sequential different extracts of Aegle marmelos leaves (AM) and Mucuna pruriens seeds (MP) by in vivo experimental models. Wistar albino rats were subjected to excision, incision and dead space wounds measuring approximately 250 mm2, 3 cm and implanting sterilized polyvinyl chloride tube on the back of each rat near either side of the vertebral column respectively. The experimental animals were randomized into eight groups (n = 6), control, standard and treatment groups. Hydrogel of different extracts were applied topically once daily. The parameters observed were percentage of wound contraction, epithelization period, tensile strength, hydroxyproline content of the granulation tissue, and histological changes during wound healing. The statistical study revealed that in excision, incision, and dead space wound models all formulations have significant (P < 0.01) wound healing potential. However, methanolic extract formulation was found to be superior to all other treatments as evidenced by rapid wound contraction, lesser number of days required for complete epithelization, increased tensile strength and significant increase in hydroxyproline content. As compared to the reference standard treated group the wound healing process of the experimental groups was decelerated. All extracts obtained from AM and MP facilitated the wound healing process in all experimental models.

  11. A systematic review of the angular values obtained by computerized photogrammetry in sagittal plane: a proposal for reference values.

    PubMed

    Krawczky, Bruna; Pacheco, Antonio G; Mainenti, Míriam R M

    2014-05-01

    Reference values for postural alignment in the coronal plane, as measured by computerized photogrammetry, have been established but not for the sagittal plane. The objective of this study is to propose reference values for angular measurements used for postural analysis in the sagittal plane for healthy adults. Electronic databases (PubMed, BVS, Cochrane, Scielo, and Science Direct) were searched using the following key words: evaluation, posture, photogrammetry, and software. Articles published between 2006 and 2012 that used the PAS/SAPO (postural assessment software) were selected. Another inclusion criterion was the presentation of, at least, one of the following measurements: head horizontal alignment, pelvic horizontal alignment, hip angle, vertical alignment of the body, thoracic kyphosis, and lumbar lordosis. Angle samples of the selected articles were grouped 2 by 2 in relation to an overall average, which made possible total average, variance, and SD calculations. Six articles were included, and the following average angular values were found: 51.42° ± 4.87° (head horizontal alignment), -12.26° ± 5.81° (pelvic horizontal alignment), -6.40° ± 3.86° (hip angle), and 1.73° ± 0.94° (vertical alignment of the body). None of the articles contained the measurements for thoracic kyphosis and lumbar lordosis. The reference values can be adopted as reference for postural assessment in future researches if the same anatomical points are considered. Copyright © 2014 National University of Health Sciences. Published by Mosby, Inc. All rights reserved.

  12. [VALUE OF SMART PHONE Scoliometer SOFTWARE IN OBTAINING OPTIMAL LUMBAR LORDOSIS DURING L4-S1 FUSION SURGERY].

    PubMed

    Yu, Weibo; Liang, De; Ye, Linqiang; Jiang, Xiaobing; Yao, Zhensong; Tang, Jingjing; Tang, Yongchao

    2015-10-01

    To investigate the value of smart phone Scoliometer software in obtaining optimal lumbar lordosis (LL) during L4-S1 fusion surgery. Between November 2014 and February 2015, 20 patients scheduled for L4-S1 fusion surgery were prospectively enrolled the study. There were 8 males and 12 females, aged 41-65 years (mean, 52.3 years). The disease duration ranged from 6 months to 6 years (mean, 3.4 years). Before operation, the pelvic incidence (PI) and Cobb angle of L4-S1 (CobbL4-S1) were measured on lateral X-ray film of lumbosacral spine by PACS system; and the ideal CobbL4-S1 was then calculated according to previously published methods [(PI+9 degrees) x 70%]. Subsequently, intraoperative CobbL4-S1 was monitored by the Scoliometer software and was defined as optimal while it was less than 5 degrees difference compared with ideal CobbL4-S1. Finally, the CobbL4-S1 was measured by the PACS system after operation and the consistency was compared between Scoliometer software and PACS system to evaluate the accuracy of this software. In addition, value of this method in obtaining optimal LL was validated by comparing the difference between ideal CobbL4-S1 and preoperative one with that between ideal CobbL4-S1 and postoperative one. The CobbL4-S1 was (36.17 ± 1.53)degrees for ideal one, (22.57 ± 5.50)degrees for preoperative one, (32.25 ± 1.46)degrees for intraoperative one measured by Scoliometer software, and (34.43 ± 1.72)degrees for postoperative one, respectively. The observed intraclass correlation coefficient (ICC) was excellent [ICC = 0.96, 95% confidence interval (0.93, 0.97)] and the mean absolute difference (MAD) was low (MAD = 1.23) between Scoliometer software and PACS system. The deviation between ideal CobbL4-S1 and postoperative CobbL4-S1 was (2.31 ± 0.23)degrees, which was significantly lower than the deviation between ideal CobbL4-S1 and preoperative CobbL4-S1 (13.60 ± 1.85)degrees (t = 6.065, P = 0.001). Scoliometer software can help surgeon obtain

  13. Experimental scheme for qubit and qutrit symmetric informationally complete positive operator-valued measurements using multiport devices

    NASA Astrophysics Data System (ADS)

    Tabia, Gelo Noel M.

    2012-12-01

    It is crucial for various quantum information processing tasks that the state of a quantum system can be determined reliably and efficiently from general quantum measurements. One important class of measurements for this purpose is symmetric informationally complete positive operator-valued measurements (SIC-POVMs). SIC-POVMs have the advantage of providing an unbiased estimator for the quantum state with the minimal number of outcomes needed for full tomography. By virtue of Naimark's dilation theorem, any POVM can always be realized with a suitable coupling between the system and an auxiliary system and by performing a projective measurement on the joint system. In practice, finding the appropriate coupling is rather nontrivial. Here we propose an experimental design for directly implementing SIC-POVMs using multiport devices and path-encoded qubits and qutrits, the utility of which has recently been demonstrated by several experimental groups around the world. Furthermore, we describe how these multiports can be attained in practice with an integrated photonic system composed of nested linear optical elements.

  14. Neutron field measurement at the Experimental Advanced Superconducting Tokamak using a Bonner sphere spectrometer

    NASA Astrophysics Data System (ADS)

    Hu, Zhimeng; Zhong, Guoqiang; Ge, Lijian; Du, Tengfei; Peng, Xingyu; Chen, Zhongjing; Xie, Xufei; Yuan, Xi; Zhang, Yimo; Sun, Jiaqi; Fan, Tieshuan; Zhou, Ruijie; Xiao, Min; Li, Kai; Hu, Liqun; Chen, Jun; Zhang, Hui; Gorini, Giuseppe; Nocente, Massimo; Tardocchi, Marco; Li, Xiangqing; Chen, Jinxiang; Zhang, Guohui

    2018-07-01

    The neutron field measurement was performed in the Experimental Advanced Superconducting Tokamak (EAST) experimental hall using a Bonner sphere spectrometer (BSS) based on a 3He thermal neutron counter. The measured spectra and the corresponding integrated neutron fluence and dose values deduced from the spectra at two exposed positions were compared to the calculated results obtained by a general Monte Carlo code MCNP5, and good agreements were found. The applicability of a homemade dose survey meter installed at EAST was also verified with the comparison of the ambient dose equivalent H*(10) values measured by the meter and BSS.

  15. Complex Values in Different Cultures: Some Research Results of Psycholinguistic Experiments with Russian and Swedish Students

    ERIC Educational Resources Information Center

    Shabes, Vladimir; Troshchenkova, Ekaterina; Potapova, Tamara; Ivarsson, Lena; Damber, Ulla; Bostedt, Goran

    2012-01-01

    In the article on the basis of the psycholinguistic experimental data obtained in 2009-2010 from Russian and Swedish students, we consider internal features of several complex values ("Harmony", "Freedom", "Democracy", "Tolerance" and "Patriotism") and analyze their external systemic organization,…

  16. On collisional disruption - Experimental results and scaling laws

    NASA Technical Reports Server (NTRS)

    Davis, Donald R.; Ryan, Eileen V.

    1990-01-01

    Both homogeneous and inhomogeneous targets have been addressed by the present experimental consideration of the impact strengths, fragment sizes, and fragment velocities generated by cement mortar targets whose crushing strengths vary by an order of magnitude, upon impact of projectiles in the velocity range of 50-5700 m/sec. When combined with additional published data, dynamic impact strength is found to correlate with quasi-static material strengths for materials ranging in character from basalt to ice; two materials not following this trend, however, are weak mortar and clay targets. Values consistent with experimental results are obtainable with a simple scaling algorithm based on impact energy, material properties, and collisional strain rate.

  17. Theoretical and experimental studies of reentry plasmas

    NASA Technical Reports Server (NTRS)

    Dunn, M. G.; Kang, S.

    1973-01-01

    A viscous shock-layer analysis was developed and used to calculate nonequilibrium-flow species distributions in the plasma layer of the RAM vehicle. The theoretical electron-density results obtained are in good agreement with those measured in flight. A circular-aperture flush-mounted antenna was used to obtain a comparison between theoretical and experimental antenna admittance in the presence of ionized boundary layers of low collision frequency. The electron-temperature and electron-density distributions in the boundary layer were independently measured. The antenna admittance was measured using a four-probe microwave reflectometer and these measured values were found to be in good agreement with those predicted. Measurements were also performed with another type of circular-aperture antenna and good agreement was obtained between the calculations and the experimental results. A theoretical analysis has been completed which permits calculation of the nonequilibrium, viscous shock-layer flow field for a sphere-cone body. Results are presented for two different bodies at several different altitudes illustrating the influences of bluntness and chemical nonequilibrium on several gas dynamic parameters of interest. Plane-wave transmission coefficients were calculated for an approximate space-shuttle body using a typical trajectory.

  18. Wood-Polymer composites obtained by gamma irradiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gago, J.; Lopez, A.; Rodriguez, J.

    2007-10-26

    In this work we impregnate three Peruvian woods (Calycophy spruceanum Be, Aniba amazonica Meiz and Hura crepitans L) with styrene-polyester resin and methyl methacrylate. The polymerization of the system was promoted by gamma radiation and the experimental optimal condition was obtained with styrene-polyester 1:1 and 15 kGy. The obtained composites show reduced water absorption and better mechanical properties compared to the original wood. The structure of the wood-polymer composites was studied by light microscopy. Water absorption and hardness were also obtained.

  19. Valuing inter-sectoral costs and benefits of interventions in the healthcare sector: methods for obtaining unit prices.

    PubMed

    Drost, Ruben M W A; Paulus, Aggie T G; Ruwaard, Dirk; Evers, Silvia M A A

    2017-02-01

    There is a lack of knowledge about methods for valuing health intervention-related costs and monetary benefits in the education and criminal justice sectors, also known as 'inter-sectoral costs and benefits' (ICBs). The objective of this study was to develop methods for obtaining unit prices for the valuation of ICBs. By conducting an exploratory literature study and expert interviews, several generic methods were developed. The methods' feasibility was assessed through application in the Netherlands. Results were validated in an expert meeting, which was attended by policy makers, public health experts, health economists and HTA-experts, and discussed at several international conferences and symposia. The study resulted in four methods, including the opportunity cost method (A) and valuation using available unit prices (B), self-constructed unit prices (C) or hourly labor costs (D). The methods developed can be used internationally and are valuable for the broad international field of HTA.

  20. Inverse Modelling to Obtain Head Movement Controller Signal

    NASA Technical Reports Server (NTRS)

    Kim, W. S.; Lee, S. H.; Hannaford, B.; Stark, L.

    1984-01-01

    Experimentally obtained dynamics of time-optimal, horizontal head rotations have previously been simulated by a sixth order, nonlinear model driven by rectangular control signals. Electromyography (EMG) recordings have spects which differ in detail from the theoretical rectangular pulsed control signal. Control signals for time-optimal as well as sub-optimal horizontal head rotations were obtained by means of an inverse modelling procedures. With experimentally measured dynamical data serving as the input, this procedure inverts the model to produce the neurological control signals driving muscles and plant. The relationships between these controller signals, and EMG records should contribute to the understanding of the neurological control of movements.

  1. Strategies for fixing the CKM-angle γ and obtaining experimental insights into the world of electroweak penguins

    NASA Astrophysics Data System (ADS)

    Fleischer, Robert

    1996-02-01

    Using the SU(3) flavour symmetry of strong interactions, we propose strategies for extracting both the CKM-angle γ and the overlineb → overlineuu overlines tree-level amplitude T‧. We present also an approximate approach using the branching ratios for the modes B+ → π+K0, Bd0 → π-K+, overlineBd0 → π +K - and B+ → π+π0 which should be rather promising from the experimental point of view. The quantities γ and T‧ determined this way may well be used as an input to control electroweak penguins in nonleptonic B-decays as has been discussed in previous work. Following these lines, we propose strategies for obtaining quantitative insights into the physics of the electroweak penguin operators and performing some consistency checks. As a by-product, we derive an upper bound of 6° for the uncertainty originating from electroweak penguins in the α-determination by means of B → ππ decays.

  2. Quasi-experimental study designs series-paper 4: uses and value.

    PubMed

    Bärnighausen, Till; Tugwell, Peter; Røttingen, John-Arne; Shemilt, Ian; Rockers, Peter; Geldsetzer, Pascal; Lavis, John; Grimshaw, Jeremy; Daniels, Karen; Brown, Annette; Bor, Jacob; Tanner, Jeffery; Rashidian, Arash; Barreto, Mauricio; Vollmer, Sebastian; Atun, Rifat

    2017-09-01

    Quasi-experimental studies are increasingly used to establish causal relationships in epidemiology and health systems research. Quasi-experimental studies offer important opportunities to increase and improve evidence on causal effects: (1) they can generate causal evidence when randomized controlled trials are impossible; (2) they typically generate causal evidence with a high degree of external validity; (3) they avoid the threats to internal validity that arise when participants in nonblinded experiments change their behavior in response to the experimental assignment to either intervention or control arm (such as compensatory rivalry or resentful demoralization); (4) they are often well suited to generate causal evidence on long-term health outcomes of an intervention, as well as nonhealth outcomes such as economic and social consequences; and (5) they can often generate evidence faster and at lower cost than experiments and other intervention studies. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Experimental Study of Axially Tension Cold Formed Steel Channel Members

    NASA Astrophysics Data System (ADS)

    Apriani, Widya; Lubis, Fadrizal; Angraini, Muthia

    2017-12-01

    Experimental testing is commonly used as one of the steps to determine the cause of the collapse of a building structure. The collapse of structures can be due to low quality materials. Although material samples have passed laboratory tests and the existing technical specifications have been met but there may be undetected defects and known material after failure. In this paper will be presented Experimental Testing of Axially Tension Cold Formed Steel Channel Members to determine the cause of the collapse of a building roof truss x in Pekanbaru. Test of tensile strength material cold formed channel sections was performed to obtain the main characteristics of Cold Formed steel material, namely ultimate tensile strength loads that can be held by members and the yield stress possessed by channel sections used in construction. Analysis of axially tension cold formed steel channel section presents in this paper was conducted through experimental study based on specificationsAnnualBook of ASTM Standards: Metal Test methods and Analitical Procedures, Section 3 (1991). The result of capacity loads experimental test was compared with design based on SNI 03-7971-2013standard of Indonesia for the design of cold formed steel structural members. The results of the yield stress of the material will be seen against the minimum allowable allowable stress range. After the test, the percentace of ultimate axial tension capacity theory has a result that is 16.46% larger than the ultimate axial tension capacity experimental. When compared with the load that must be borne 5.673 kN/m it can be concluded that 2 specimens do not meet. Yield stress of member has fulfilled requirement that wass bigger than 550 MPa. Based on the curve obtained ultimate axial tension capacity theory, results greater than experimental. The greatest voltage value (fu) is achieved under the same conditions as its yield stress. For this specimen with a melting voltage value fy = 571.5068 MPa has fulfilled the

  4. Experimental Study of Axially Tension Cold Formed Steel Channel Members

    NASA Astrophysics Data System (ADS)

    Apriani, Widya; Lubis, Fadrizal; Angraini, Muthia

    2017-12-01

    Experimental testing is commonly used as one of the steps to determine the cause of the collapse of a building structure. The collapse of structures can be due to low quality materials. Although material samples have passed laboratory tests and the existing technical specifications have been met but there may be undetected defects and known material after failure. In this paper will be presented Experimental Testing of Axially Tension Cold Formed Steel Channel Members to determine the cause of the collapse of a building roof truss x in Pekanbaru. Test of tensile strength material cold formed channel sections was performed to obtain the main characteristics of Cold Formed steel material, namely ultimate tensile strength loads that can be held by members and the yield stress possessed by channel sections used in construction. Analysis of axially tension cold formed steel channel section presents in this paper was conducted through experimental study based on specificationsAnnualBook of ASTM Standards: Metal Test methods and Analitical Procedures, Section 3 (1991). The result of capacity loads experimental test was compared with design based on SNI 03-7971- 2013standard of Indonesia for the design of cold formed steel structural members. The results of the yield stress of the material will be seen against the minimum allowable allowable stress range. After the test, the percentace of ultimate axial tension capacity theory has a result that is 16.46% larger than the ultimate axial tension capacity experimental. When compared with the load that must be borne 5.673 kN/m it can be concluded that 2 specimens do not meet. Yield stress of member has fulfilled requirement that wass bigger than 550 MPa. Based on the curve obtained ultimate axial tension capacity theory, results greater than experimental. The greatest voltage value (fu) is achieved under the same conditions as its yield stress. For this specimen with a melting voltage value fy = 571.5068 MPa has fulfilled the

  5. Obtaining the Iodine Value of Various Oils via Bromination with Pyridinium Tribromide

    ERIC Educational Resources Information Center

    Simurdiak, Michael; Olukoga, Olushola; Hedberg, Kirk

    2016-01-01

    A laboratory exercise was devised that allows students to rapidly and fairly accurately determine the iodine value of oleic acid. This method utilizes the addition of elemental bromine to the unsaturated bonds in oleic acid, due to bromine's relatively fast reaction rate compared to that of the traditional Wijs solution method. This method also…

  6. Conceptual beliefs about human values and their implications: human nature beliefs predict value importance, value trade-offs, and responses to value-laden rhetoric.

    PubMed

    Bain, Paul G; Kashima, Yoshihisa; Haslam, Nick

    2006-08-01

    Beliefs that may underlie the importance of human values were investigated in 4 studies, drawing on research that distinguishes natural-kind (natural), nominal-kind (conventional), and artifact (functional) beliefs. Values were best characterized by artifact and nominal-kind beliefs, as well as a natural-kind belief specific to the social domain, "human nature" (Studies 1 and 2). The extent to which values were considered central to human nature was associated with value importance in both Australia and Japan (Study 2), and experimentally manipulating human nature beliefs influenced value importance (Study 3). Beyond their association with importance, human nature beliefs predicted participants' reactions to value trade-offs (Study 1) and to value-laden rhetorical statements (Study 4). Human nature beliefs therefore play a central role in the psychology of values.

  7. Stable isotopes to discriminate lambs fed herbage or concentrate both obtained from C(3) plants.

    PubMed

    Moreno-Rojas, Jose M; Vasta, Valentina; Lanza, Alfio; Luciano, Giuseppe; Ladroue, Virginie; Guillou, Claude; Priolo, Alessandro

    2008-12-01

    This study was aimed at determining whether isotopic ratio mass spectrometry (IRMS) enables us to discriminate between lambs fed herbage or concentrate, both obtained from C(3) plants, and those fed a concentrate obtained from C(4) plants. Thirty-four Comisana male lambs (age 45 days) were assigned to three feeding treatments. Fourteen lambs were fed vetch (Vicia sativa) ad libitum. Another fourteen lambs received a barley-based concentrate. The remaining six lambs were fed a maize-based concentrate. After 60 days of experimental treatment the animals were slaughtered and the wool, perirenal fat and muscle longissimus dorsi were sampled. The delta(13)C and delta(15)N values of the muscle, wool and feed were measured by continuous flow elemental analysis (CF-EA)-IRMS. The delta(13)C of the fat was determined likewise. The isotopic composition of the tissues reflected that of the three diets. For the lambs which were fed herbage the muscle delta(13)C values were higher (P < 0.0005) and delta(15)N values were lower (P < 0.0005) than those of the lambs receiving concentrates. The delta(15)N and delta(13)C values in the muscle and delta(13)C values in the adipose tissue allowed perfect discrimination between the lambs fed the three different diets. The regression between the delta(13)C values measured in muscle and in wool of lambs was linear (R(2) = 0.99; P < 0.0005). This result shows that delta(13)C measured in the wool can predict muscle delta(13)C distribution, suggesting that wool is a valuable matrix for meat authentication.

  8. Tufted capuchins (Cebus apella) attribute value to foods and tools during voluntary exchanges with humans.

    PubMed

    Westergaard, Gregory C; Liv, Chanya; Rocca, Andrea M; Cleveland, Allison; Suomi, Stephen J

    2004-01-01

    This research examined exchange and value attribution in tufted capuchin monkeys ( Cebus apella). We presented subjects with opportunities to obtain various foods and a tool from an experimenter in exchange for the foods or tool in the subjects' possession. The times elapsed before the first chow biscuits were expelled and/or an exchange took place were recorded as the dependent measures. Laboratory chow biscuits, grapes, apples, and a metal bolt (a tool used to probe for syrup) were used as experimental stimuli. The subjects demonstrated the ability to recognize that exchanges could occur when an experimenter was present with a desirable food. Results indicate that subjects exhibited significant variation in their willingness to barter based upon the types of foods that were both in their possession and presented by the experimenter. Subjects more readily traded chow biscuits for fruit, and more readily traded apples for grapes than grapes for apples. During the exchange of tools and food, the subjects preferred the following in descending order when the probing apparatus was baited with sweet syrup: grapes, metal bolts, and chow biscuits. However when the apparatus was not baited, the values changed to the following in descending order: grapes, chow, and metal bolts. These results indicate that tufted capuchins recognize opportunities to exchange and engage in a simple barter system whereby low-valued foods are readily traded for more highly valued food. Furthermore, these capuchins demonstrate that their value for a tool changes depending upon its utility.

  9. Molecular identification of Heterakis spumosa obtained from brown rats (Rattus norvegicus) in Japan and its infectivity in experimental mice.

    PubMed

    Šnábel, Viliam; Utsuki, Daisuke; Kato, Takehiro; Sunaga, Fujiko; Ooi, Hong-Kean; Gambetta, Barbara; Taira, Kensuke

    2014-09-01

    Heterakis spumosa is a nematode of invasive rodents, mainly affiliated with Rattus spp. of Asian origin. Despite the ecological importance and cosmopolitan distribution, little information is available on the genetic characteristics and infectivity to experimental animals of this roundworm. Heterakis isolates obtained from naturally infected brown rats caught in 2007 in the city of Sagamihara, east central Honshu, Japan, and maintained by laboratory passages were subjected to mitochondrial sequence analysis and experimental infection in mice. Sequencing of the cox1 gene revealed that nucleotides of H. spumosa and previously examined Heterakis isolonche isolates from gallinaceous birds in Japan differed by 11.2-12.2% that conforms to the range expected for interspecific differences. The two H. spumosa isolates differed by a single 138T/C non-synonymous substitution in the 393-bp mt sequence. In a dendrogram, the H. spumosa samples formed a subcluster with members of the nematode superfamily Heterakoidea, H. isolonche and Ascaridia galli. In an experimental infection study, ICR, AKR, B10.BR and C57BL/6 mice strains were inoculated with 200 H. spumosa eggs/head and necropsied at 14 and 90 days post-inoculation (DPI) when the number of worms was recorded. Eggs were initially detected in faeces from 32-35 DPI in ICR, AKR and B10.BR mice and the highest mean number of eggs per gram of faeces (EPG) was 4,800 at 38 DPI, 2,200 at 58 DPI and 800 at 44 and 72 DPI in ICR, AKR and B10.BR mice, respectively. No eggs were observed in faeces of the C57BL/6 mouse strain during the experiment. A similar number of juvenile worms were isolated from all mouse strains at 14 DPI, whereas no adult worms were detected in C57BL/6 mice at 90 DPI.

  10. A closer look at the physical and optical properties of gold nanostars: an experimental and computational study

    DOE PAGES

    Tsoulos, T. V.; Han, L.; Weir, J.; ...

    2017-02-22

    A combined experimental and computational study was carried out to design a semi-empirical method to determine the volume, surface area, and extinction coefficients of gold nanostars. The values obtained were confirmed by reconstructing the nanostar 3D topography through high-tilt TEM tomography and introducing the finite elements in COMSOL Multiphysics through which we have also calculated the morphology-dependent extinction coefficient. We have, for the first time, modeled the heat losses of a real, experimentally synthesized nanostar, and found the plasmon resonances to be in excellent agreement with those obtained experimentally. Furthermore, we believe that our approach could substantially improve the applicabilitymore » of this remarkable nanomaterial.« less

  11. A closer look at the physical and optical properties of gold nanostars: an experimental and computational study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tsoulos, T. V.; Han, L.; Weir, J.

    A combined experimental and computational study was carried out to design a semi-empirical method to determine the volume, surface area, and extinction coefficients of gold nanostars. The values obtained were confirmed by reconstructing the nanostar 3D topography through high-tilt TEM tomography and introducing the finite elements in COMSOL Multiphysics through which we have also calculated the morphology-dependent extinction coefficient. We have, for the first time, modeled the heat losses of a real, experimentally synthesized nanostar, and found the plasmon resonances to be in excellent agreement with those obtained experimentally. Furthermore, we believe that our approach could substantially improve the applicabilitymore » of this remarkable nanomaterial.« less

  12. Experimental measurement of flexion-extension movement in normal and corpse prosthetic elbow joint.

    PubMed

    TarniŢă, Daniela; TarniŢă, DănuŢ Nicolae

    2016-01-01

    This paper presents a comparative experimental study of flexion-extension movement in healthy elbow and in the prosthetic elbow joint fixed on an original experimental bench. Measurements were carried out in order to validate the functional morphology and a new elbow prosthesis type ball head. The three-dimensional (3D) model and the physical prototype of our experimental bench used to test elbow endoprosthesis at flexion-extension and pronation-supination movements is presented. The measurements were carried out on a group of nine healthy subjects and on the prosthetic corpse elbow, the experimental data being obtained for flexion-extension movement cycles. Experimental data for the two different flexion-extension tests for the nine subjects and for the corpse prosthetic elbow were acquired using SimiMotion video system. Experimental data were processed statistically. The corresponding graphs were obtained for all subjects in the experimental group, and for corpse prosthetic elbow for both flexion-extension tests. The statistical analysis has proved that the flexion angles of healthy elbows were significantly close to the values measured at the prosthetic elbow fixed on the experimental bench. The studied elbow prosthesis manages to re-establish the mobility for the elbow joint as close to the normal one.

  13. Evaluation of Anti-Candida Activity of Vitis vinifera L. Seed Extracts Obtained from Wine and Table Cultivars

    PubMed Central

    Santamaria, Anna Rita; D'Auria, Felicia Diodata; Innocenti, Marzia; Gabrielli, Elena; Panella, Simona; Antonacci, Donato; Palamara, Anna Teresa; Vecchiarelli, Anna

    2014-01-01

    For the first time, grape seed extracts (GSEs), obtained from wine and table cultivars of Vitis vinifera L., cultured in experimental fields of Lazio and Puglia regions of Italy and grown in different agronomic conditions, have been tested on 43 Candida species strains. We demonstrated a significant correlation between the content of the flavan-3-ols in GSEs extracts, with a polymerization degree ≥4, and anti-Candida activity. Moreover, we demonstrated that GSEs, obtained from plants cultured with reduced irrigation, showed a content of polymeric flavan-3-ols >250 mg/g with geometric mean MIC values between 5.7 and 20.2 mg/L against Candida albicans reference strains. GSE, showing 573 mg/g of polymeric flavan-3-ols, has been tested in an experimental murine model of vaginal candidiasis by using noninvasive in vivo imaging technique. The results pointed out a significant inhibition of Candida albicans load 5 days after challenge. These findings indicate that GSEs with high content of polymeric flavan-3-ols can be used in mucosal infection as vaginal candidiasis. PMID:24864227

  14. Histology of Testicular Biopsies Obtained for Experimental Fertility Preservation Protocol in Boys with Cancer.

    PubMed

    Pietzak, Eugene J; Tasian, Gregory E; Tasian, Sarah K; Brinster, Ralph L; Carlson, Claire; Ginsberg, Jill P; Kolon, Thomas F

    2015-11-01

    Cryopreservation of testicular tissue with subsequent reimplantation after therapy has the potential to preserve fertility for prepubertal boys with cancer. We present the histology and feasibility of testicular tissue procurement for this novel approach. We performed a prospective cohort study of boys at significant risk for treatment associated gonadotoxicity who were eligible for an experimental research protocol between 2008 and 2011. Open testicular biopsy was performed while the patients were anesthetized for another treatment related procedure. Half of the specimen was reserved for cryopreservation, while the other half was used for research purposes. Semithin sections of the biopsy specimens were evaluated for histological features and compared to age adjusted reference values. A total of 34 boys underwent biopsy between March 2008 and October 2011. Of the patients 29 had solid tumors and 5 underwent hematopoietic stem cell transplantation for benign disease. A total of 27 patients had adequate tissue for histological analysis. Median patient age was 8.7 years (IQR 2.2 to 11.5). All children had either normal (81.5% of patients) or increased (18.5%) numbers of germ cells per tubule for their age. However, 5 of 26 patients (19%) older than 6 months had no evidence of adult dark spermatogonia and 9 of 16 (56%) older than 6 years had no evidence of primary spermatocytes on biopsy, which would be expected based on age norms. These findings are suggestive of abnormal germ cell maturation. The preliminary histological findings of abnormal spermatogenesis maturation in the testes of prepubertal boys with cancer warrants further investigation. Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  15. Comparison of the T2-star Values of Placentas Obtained from Pre-eclamptic Patients with Those of a Control Group: an Ex-vivo Magnetic Resonance Imaging Study.

    PubMed

    Yurttutan, Nursel; Bakacak, Murat; Kızıldağ, Betül

    2017-09-29

    Endotel dysfunction, vasoconstriction, and oxidative stress are described in the pathophysiology of pre-eclampsia, but its aetiology has not been revealed clearly. To examine whether there is a difference between the placentas of pre-eclamptic pregnant women and those of a control group in terms of their T2 star values. Case-control study. Twenty patients diagnosed with pre-eclampsia and 22 healthy controls were included in this study. The placentas obtained after births performed via Caesarean section were taken into the magnetic resonance imaging area in plastic bags within the first postnatal hour, and imaging was performed via modified DIXON-Quant sequence. Average values were obtained by performing T2 star measurements from four localisations on the placentas. T2 star values measured in the placentas of the control group were found to be significantly lower than those in the pre-eclampsia group (p<0.01). While the mean T2 star value in the pre-eclamptic group was found to be 37.48 ms (standard deviation ± 11.3), this value was 28.74 (standard deviation ± 8.08) in the control group. The cut-off value for the T2 star value, maximising the accuracy of diagnosis, was 28.59 ms (area under curve: 0.741; 95% confidence interval: 0.592-0.890); sensitivity and specificity were 70% and 63.6%, respectively. This study, the T2 star value, which is an indicator of iron amount, was found to be significantly lower in the control group than in the pre-eclampsia group. This may be related to the reduction in blood flow to the placenta due to endothelial dysfunction and vasoconstriction, which are important in pre-eclampsia pathophysiology.

  16. Correlation of Lactic Acid and Base Deficit Values Obtained From Arterial and Peripheral Venous Samples in a Pediatric Population During Intraoperative Care.

    PubMed

    Bordes, Brianne M; Walia, Hina; Sebastian, Roby; Martin, David; Tumin, Dmitry; Tobias, Joseph D

    2017-12-01

    Lactic acid and base deficit (BD) values are frequently monitored in the intensive care unit and operating room setting to evaluate oxygenation, ventilation, cardiac output, and peripheral perfusion. Although generally obtained from an arterial cannula, such access may not always be available. The current study prospectively investigates the correlation of arterial and peripheral venous values of BD and lactic acid. The study cohort included 48 patients. Arterial BD values ranged from -8 to 4 mEq/L and peripheral venous BD values ranged from -8 to 4 mEq/L. Arterial lactic acid values ranged from 0.36 to 2.45 μmol/L and peripheral venous lactic acid values ranged from 0.38 to 4 μmol/L. The arterial BD (-0.4 ± 2.2 mEq/L) was not significantly different from the peripheral venous BD (-0.6 ± 2.2 mEq/L). The arterial lactic acid (1.0 ± 0.5 μmol/L) was not significantly different from the peripheral venous lactic acid (1.1 ± 0.6 μmol/L). Pearson correlation coefficients demonstrated a very high correlation between arterial and peripheral venous BD ( r = .88, P < .001) and between arterial and peripheral venous lactic acid ( r = .67, P < .001). Bland-Altman plots of both pairs of measures showed that the majority of observations fell within the 95% limits of agreement. Least-squares regression indicated that a 1-unit increase in arterial BD corresponded to a 0.9-unit increase in peripheral venous BD (95% confidence interval [CI]: 0.7-1.0; P < .001) and a 1-unit increase in arterial lactic acid corresponded to a 0.9-unit increase in peripheral venous lactic acid (95% CI: 0.6-1.2; P < .001). These data demonstrate that there is a clinically useful correlation between arterial and peripheral venous lactic acid and BD values.

  17. FOCUSING OF HIGH POWER ULTRASOUND BEAMS AND LIMITING VALUES OF SHOCK WAVE PARAMETERS

    PubMed Central

    Bessonova, O.V.; Khokhlova, V.A.; Bailey, M.R.; Canney, M.S.; Crum, L.A.

    2009-01-01

    In this work, the influence of nonlinear and diffraction effects on amplification factors of focused ultrasound systems is investigated. The limiting values of acoustic field parameters obtained by focusing of high power ultrasound are studied. The Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation was used for the numerical modeling. Solutions for the nonlinear acoustic field were obtained at output levels corresponding to both pre- and post- shock formation conditions in the focal area of the beam in a weakly dissipative medium. Numerical solutions were compared with experimental data as well as with known analytic predictions. PMID:20161349

  18. FOCUSING OF HIGH POWER ULTRASOUND BEAMS AND LIMITING VALUES OF SHOCK WAVE PARAMETERS.

    PubMed

    Bessonova, O V; Khokhlova, V A; Bailey, M R; Canney, M S; Crum, L A

    2009-07-21

    In this work, the influence of nonlinear and diffraction effects on amplification factors of focused ultrasound systems is investigated. The limiting values of acoustic field parameters obtained by focusing of high power ultrasound are studied. The Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation was used for the numerical modeling. Solutions for the nonlinear acoustic field were obtained at output levels corresponding to both pre- and post- shock formation conditions in the focal area of the beam in a weakly dissipative medium. Numerical solutions were compared with experimental data as well as with known analytic predictions.

  19. Focusing of high power ultrasound beams and limiting values of shock wave parameters

    NASA Astrophysics Data System (ADS)

    Bessonova, O. V.; Khokhlova, V. A.; Bailey, M. R.; Canney, M. S.; Crum, L. A.

    2009-10-01

    In this work, the influence of nonlinear and diffraction effects on amplification factors of focused ultrasound systems is investigated. The limiting values of acoustic field parameters obtained by focusing of high power ultrasound are studied. The Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation was used for the numerical modeling. Solutions for the nonlinear acoustic field were obtained at output levels corresponding to both pre- and post-shock formation conditions in the focal area of the beam in a weakly dissipative medium. Numerical solutions were compared with experimental data as well as with known analytic predictions.

  20. Using the Climbing Drum Peel (CDP) Test to Obtain a G(sub IC) value for Core/Facesheet Bonds

    NASA Technical Reports Server (NTRS)

    Nettles, A. T.; Gregory, Elizabeth D.; Jackson, Justin R.

    2006-01-01

    A method of measuring the Mode I fracture toughness of core/facesheet bonds in sandwich Structures is desired, particularly with the widespread use of models that need this data as input. This study examined if a critical strain energy release rate, G(sub IC), can be obtained from the climbing drum peel (CDP) test. The CDP test is relatively simple to perform and does not rely on measuring small crack lengths such as required by the double cantilever beam (DCB) test. Simple energy methods were used to calculate G(sub IC) from CDP test data on composite facesheets bonded to a honeycomb core. Facesheet thicknesses from 2 to 5 plies were tested to examine the upper and lower bounds on facesheet thickness requirements. Results from the study suggest that the CDP test, with certain provisions, can be used to find the GIG value of a core/facesheet bond.

  1. Technical and technological solution for vegetal bio-stimulants obtaining

    NASA Astrophysics Data System (ADS)

    Anghelache, D. G.; Diaconescu, I.; Pătraşcu, R.

    2017-08-01

    The paper presents a modern technology for bio fertilizers resulted from waste plant mass after harvesting crops Experimental products were obtained rich in nutrients, but unstable in terms of existing microorganisms. Therefore, they conducted further studies to obtaining bio fungicide herb, so in all investigations undertaken so far in the laboratory, were able to conclude that the introduction of medicinal plant extracts with fungicidal effect into the bio fertilizers obtained by degradation of plant material post-harvest can get various bio-stimulants with nourishing effect upon the plants. Following this technology the paper’s objective is to identify a flux scheme for experimental equipment which can produce as final outcome this type of bio-stimulant. Also, in this work, this equipment will be chosen and will be designed following and obeying to the request of every step of the above technology.

  2. Experimental verification of numerical calculations of railway passenger seats

    NASA Astrophysics Data System (ADS)

    Ligaj, B.; Wirwicki, M.; Karolewska, K.; Jasińska, A.

    2018-04-01

    The construction of railway seats is based on industry regulations and the requirements of end users, i.e. passengers. The two main documents in this context are the UIC 566 (3rd Edition, dated 7 January 1994) and the EN 12663-1: 2010+A1:2014. The study was to carry out static load tests of passenger seat frames. The paper presents the construction of the test bench and the results of experimental and numerical studies of passenger seat rail frames. The test bench consists of a frame, a transverse beam, two electric cylinders with a force value of 6 kN, and a strain gauge amplifier. It has a modular structure that allows for its expansion depending on the structure of the seats. Comparing experimental results with numerical results for points A and B allowed to determine the existing differences. It follows from it that higher stress values are obtained by numerical calculations in the range of 0.2 MPa to 35.9 MPa.

  3. Validating proposed migration equation and parameters' values as a tool to reproduce and predict 137Cs vertical migration activity in Spanish soils.

    PubMed

    Olondo, C; Legarda, F; Herranz, M; Idoeta, R

    2017-04-01

    This paper shows the procedure performed to validate the migration equation and the migration parameters' values presented in a previous paper (Legarda et al., 2011) regarding the migration of 137 Cs in Spanish mainland soils. In this paper, this model validation has been carried out checking experimentally obtained activity concentration values against those predicted by the model. This experimental data come from the measured vertical activity profiles of 8 new sampling points which are located in northern Spain. Before testing predicted values of the model, the uncertainty of those values has been assessed with the appropriate uncertainty analysis. Once establishing the uncertainty of the model, both activity concentration values, experimental versus model predicted ones, have been compared. Model validation has been performed analyzing its accuracy, studying it as a whole and also at different depth intervals. As a result, this model has been validated as a tool to predict 137 Cs behaviour in a Mediterranean environment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. 47 CFR 54.615 - Obtaining services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... provided under § 54.621, that the requester cannot obtain toll-free access to an Internet service provider... thing of value; (6) If the service or services are being purchased as part of an aggregated purchase...

  5. Experimental determination of useful resistance value during pasta dough kneading

    NASA Astrophysics Data System (ADS)

    Podgornyj, Yu I.; Martynova, T. G.; Skeeba, V. Yu; Kosilov, A. S.; Chernysheva, A. A.; Skeeba, P. Yu

    2017-10-01

    There is a large quantity of materials produced in the form of dry powder or low humidity granulated masses in the modern market, and there is a need to develop new manufacturing machinery and to renew the existing facilities involved in the production of various loose mixtures. One of the machinery upgrading tasks is enhancing its performance. In view of the fact that experimental research is not feasible in full-scale samples, an experimental installation was to be constructed. The article contains its kinematic scheme and the 3D model. The angle of the kneading blade location, the volume of the loose mixture, rotating frequency and the number of the work member double passes were chosen as variables to carry out the experiment. The technique of the experiment, which includes two stages for the rotary and reciprocating movement of the work member, was proposed. The results of the experimental data processing yield the correlations between the load characteristics of the mixer work member and the angle of the blade, the volume of the mixture and the work member rotating frequency, allowing for the recalculation of loads for this type machines.

  6. Experimental Method for Characterizing Electrical Steel Sheets in the Normal Direction

    PubMed Central

    Hihat, Nabil; Lecointe, Jean Philippe; Duchesne, Stephane; Napieralska, Ewa; Belgrand, Thierry

    2010-01-01

    This paper proposes an experimental method to characterise magnetic laminations in the direction normal to the sheet plane. The principle, which is based on a static excitation to avoid planar eddy currents, is explained and specific test benches are proposed. Measurements of the flux density are made with a sensor moving in and out of an air-gap. A simple analytical model is derived in order to determine the permeability in the normal direction. The experimental results for grain oriented steel sheets are presented and a comparison is provided with values obtained from literature. PMID:22163394

  7. A Comparison of Analytical and Experimental Data for a Magnetic Actuator

    NASA Technical Reports Server (NTRS)

    Groom, Nelson J.; Bloodgood, V. Dale, Jr.

    2000-01-01

    Theoretical and experimental force-displacement and force-current data are compared for two configurations of a simple horseshoe, or bipolar, magnetic actuator. One configuration utilizes permanent magnet wafers to provide a bias flux and the other configuration has no source of bias flux. The theoretical data are obtained from two analytical models of each configuration. One is an ideal analytical model which is developed under the following assumptions: (1) zero fringing and leakage flux, (2) zero actuator coil mmf loss, and (3) infinite permeability of the actuator core and suspended element flux return path. The other analytical model, called the extended model, is developed by adding loss and leakage factors to the ideal model. The values of the loss and leakage factors are calculated from experimental data. The experimental data are obtained from a magnetic actuator test fixture, which is described in detail. Results indicate that the ideal models for both configurations do not match the experimental data very well. However, except for the range around zero force, the extended models produce a good match. The best match is produced by the extended model of the configuration with permanent magnet flux bias.

  8. Experimental study of the oscillation of spheres in an acoustic levitator.

    PubMed

    Andrade, Marco A B; Pérez, Nicolás; Adamowski, Julio C

    2014-10-01

    The spontaneous oscillation of solid spheres in a single-axis acoustic levitator is experimentally investigated by using a high speed camera to record the position of the levitated sphere as a function of time. The oscillations in the axial and radial directions are systematically studied by changing the sphere density and the acoustic pressure amplitude. In order to interpret the experimental results, a simple model based on a spring-mass system is applied in the analysis of the sphere oscillatory behavior. This model requires the knowledge of the acoustic pressure distribution, which was obtained numerically by using a linear finite element method (FEM). Additionally, the linear acoustic pressure distribution obtained by FEM was compared with that measured with a laser Doppler vibrometer. The comparison between numerical and experimental pressure distributions shows good agreement for low values of pressure amplitude. When the pressure amplitude is increased, the acoustic pressure distribution becomes nonlinear, producing harmonics of the fundamental frequency. The experimental results of the spheres oscillations for low pressure amplitudes are consistent with the results predicted by the simple model based on a spring-mass system.

  9. Laser-induced fluorescence detection of lead atoms in a laser-induced plasma: An experimental analytical optimization study

    NASA Astrophysics Data System (ADS)

    Laville, Stéphane; Goueguel, Christian; Loudyi, Hakim; Vidal, François; Chaker, Mohamed; Sabsabi, Mohamad

    2009-04-01

    The combination of the laser-induced breakdown spectroscopy (LIBS) and laser-induced fluorescence (LIF) techniques was investigated to improve the limit of detection (LoD) of trace elements in solid matrices. The influence of the main experimental parameters on the LIF signal, namely the ablation fluence, the excitation energy, and the inter-pulse delay, was studied experimentally and a discussion of the results was presented. For illustrative purpose we considered detection of lead in brass samples. The plasma was produced by a Q-switched Nd:YAG laser and then re-excited by a nanosecond Optical Parametric Oscillator (OPO) laser. The experiments were performed in air at atmospheric pressure. We found out that the optimal conditions were obtained for our experimental set-up using relatively weak ablation fluence of 2-3 J/cm 2 and an inter-pulse delay of about 5-10 μs. Also, a few tens of microjoules was typically required to maximize the LIF signal. Using the LIBS-LIFS technique, a single-shot LoD for lead of about 1.5 part per million (ppm) was obtained while a value of 0.2 ppm was obtained after accumulating over 100 shots. These values represent an improvement of about two orders of magnitude with respect to LIBS.

  10. WE-G-18C-02: Estimation of Optimal B-Value Set for Obtaining Apparent Diffusion Coefficient Free From Perfusion in Non-Small Cell Lung Cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Karki, K; Hugo, G; Ford, J

    2014-06-15

    Purpose: Diffusion-weighted MRI (DW-MRI) is increasingly being investigated for radiotherapy planning and response assessment. Selection of a limited number of b-values in DW-MRI is important to keep geometrical variations low and imaging time short. We investigated various b-value sets to determine an optimal set for obtaining monoexponential apparent diffusion coefficient (ADC) close to perfusion-insensitive intravoxel incoherent motion (IVIM) model ADC (ADC IVIM) in nonsmall cell lung cancer. Methods: Seven patients had 27 DW-MRI scans before and during radiotherapy in a 1.5T scanner. Respiratory triggering was applied to the echo-planar DW-MRI with TR=4500ms approximately, TE=74ms, pixel size=1.98X1.98mm{sub 2}, slice thickness=4–6mm andmore » 7 axial slices. Diffusion gradients were applied to all three axes producing traceweighted images with eight b-values of 0–1000μs/μm{sup 2}. Monoexponential model ADC values using various b-value sets were compared to ADC IVIM using all b-values. To compare the relative noise in ADC maps, intra-scan coefficient of variation (CV) of active tumor volumes was computed. Results: ADC IVIM, perfusion coefficient and perfusion fraction for tumor volumes were in the range of 880-1622 μm{sup 2}/s, 8119-33834 μm{sup 2}/s and 0.104–0.349, respectively. ADC values using sets of 250, 800 and 1000; 250, 650 and 1000; and 250–1000μs/μm{sup 2} only were not significantly different from ADC IVIM(p>0.05, paired t-test). Error in ADC values for 0–1000, 50–1000, 100–1000, 250–1000, 500–1000, and three b-value sets- 250, 500 and 1000; 250, 650 and 1000; and 250, 800 and 1000μs/μm{sup 2} were 15.0, 9.4, 5.6, 1.4, 11.7, 3.7, 2.0 and 0.2% relative to the reference-standard ADC IVIM, respectively. Mean intrascan CV was 20.2, 20.9, 21.9, 24.9, 32.6, 25.8, 25.4 and 24.8%, respectively, whereas that for ADC IVIM was 23.3%. Conclusion: ADC values of two 3 b-value sets (250, 650 and 1000; and 250, 800 and 1000μs/μm{sup 2

  11. Feasibility of using near-infrared spectroscopy to diagnose testicular torsion: an experimental study in sheep.

    PubMed

    Capraro, Geoffrey A; Mader, Timothy J; Coughlin, Bret F; Lovewell, Carolanne; St Louis, Myron R L; Tirabassi, Michael; Wadie, George; Smithline, Howard A

    2007-04-01

    To assess whether near-infrared spectroscopy can detect testicular hypoxia in a sheep model of testicular torsion within 6 hours of experimental torsion. This was a randomized, controlled, nonblinded study. Trans-scrotal, near-infrared, spectroscopy-derived testicular tissue saturation of oxygen values were obtained from the posterior hemiscrota of 6 anesthetized sheep at baseline and every 15 minutes for 6 hours after either experimental-side, 720-degree, unilateral, medial testicular torsion and orchidopexy or control-side sham procedure with orchidopexy and then for 75 minutes after reduction of torsion and pexy. Color Doppler ultrasonography was performed every 30 minutes to confirm loss of vascular flow on the experimental side, return of flow after torsion reduction, and preserved flow on the control side. Near infrared spectroscopy detected a prompt, sustained reduction in testicular tissue saturation of oxygen after experimental torsion. Further, it documented a rapid return of these values to pretorsion levels after reduction of torsion. Experimental-side testicular tissue saturation of oxygen fell from a median value of 59% (interquartile range [IQR] 57% to 69%) at baseline to 14% (IQR 11% to 29%) at 2.5 hours of torsion, and postreduction values were approximately 70%. Control-side testicular tissue saturation of oxygen values increased from a median value of 67% (IQR 59% to 68%) at baseline to 77% (IQR 77% to 94%) at 2.5 hours and remained at approximately 80% for the entire protocol. The difference in median testicular tissue saturation of oxygen between experimental and control sides, using the Friedman test, was found to be significant (P=.017). This study demonstrates the feasibility, in a sheep model, of using near-infrared spectroscopy for the noninvasive diagnosis of testicular torsion and for quantification of reperfusion after torsion reduction. The applicability of these findings, from an animal model using complete torsion, to the clinical

  12. Characterisation of transition state structures for protein folding using 'high', 'medium' and 'low' {Phi}-values.

    PubMed

    Geierhaas, Christian D; Salvatella, Xavier; Clarke, Jane; Vendruscolo, Michele

    2008-03-01

    It has been suggested that Phi-values, which allow structural information about transition states (TSs) for protein folding to be obtained, are most reliably interpreted when divided into three classes (high, medium and low). High Phi-values indicate almost completely folded regions in the TS, intermediate Phi-values regions with a detectable amount of structure and low Phi-values indicate mostly unstructured regions. To explore the extent to which this classification can be used to characterise in detail the structure of TSs for protein folding, we used Phi-values divided into these classes as restraints in molecular dynamics simulations. This type of procedure is related to that used in NMR spectroscopy to define the structure of native proteins from the measurement of inter-proton distances derived from nuclear Overhauser effects. We illustrate this approach by determining the TS ensembles of five proteins and by showing that the results are similar to those obtained by using as restraints the actual numerical Phi-values measured experimentally. Our results indicate that the simultaneous consideration of a set of low-resolution Phi-values can provide sufficient information for characterising the architecture of a TS for folding of a protein.

  13. Effectiveness of Student Learning during Experimental Work in Primary School.

    PubMed

    Logar, Ana; Peklaj, Cirila; Ferk Savec, Vesna

    2017-09-01

    The aim of the research was to optimize the effectiveness of student learning based on experimental work in chemistry classes in Slovenian primary schools. To obtain evidence about how experimental work is implemented during regular chemistry classes, experimental work was videotaped during 19 units of chemistry lessons at 12 Slovenian primary schools from the pool of randomly selected schools. Altogether 332 eight-grade students were involved in the investigation, with an average age of 14.2 years. Students were videotaped during chemistry lessons, and their worksheets were collected afterward. The 12 chemistry teachers, who conducted lessons in these schools, were interviewed before the lessons; their teaching plans were also collected. The collected data was analyzed using qualitative methods. The results indicate that many teachers in Slovenian primary schools are not fully aware of the potential of experimental work integrated into chemistry lessons for the development of students' experimental competence. Further research of the value of different kinds of training to support teachers for the use of experimental work in chemistry teaching is needed.

  14. Three-dimensional inviscid analysis of radial-turbine flow and a limited comparison with experimental data

    NASA Technical Reports Server (NTRS)

    Choo, Y. K.; Civinskas, K. C.

    1985-01-01

    The three-dimensional inviscid DENTON code is used to analyze flow through a radial-inflow turbine rotor. Experimental data from the rotor are compared with analytical results obtained by using the code. The experimental data available for comparison are the radial distributions of circumferentially averaged values of absolute flow angle and total pressure downstream of the rotor exit. The computed rotor-exit flow angles are generally underturned relative to the experimental values, which reflect the boundary-layer separation at the trailing edge and the development of wakes downstream of the rotor. The experimental rotor is designed for a higher-than-optimum work factor of 1.126 resulting in a nonoptimum positive incidence and causing a region of rapid flow adjustment and large velocity gradients. For this experimental rotor, the computed radial distribution of rotor-exit to turbine-inlet total pressure ratios are underpredicted due to the errors in the finite-difference approximations in the regions of rapid flow adjustment, and due to using the relatively coarser grids in the middle of the blade region where the flow passage is highly three-dimensional. Additional results obtained from the three-dimensional inviscid computation are also presented, but without comparison due to the lack of experimental data. These include quasi-secondary velocity vectors on cross-channel surfaces, velocity components on the meridional and blade-to-blade surfaces, and blade surface loading diagrams. Computed results show the evolution of a passage vortex and large streamline deviations from the computational streamwise grid lines. Experience gained from applying the code to a radial turbine geometry is also discussed.

  15. Three-dimensional inviscid analysis of radial turbine flow and a limited comparison with experimental data

    NASA Technical Reports Server (NTRS)

    Choo, Y. K.; Civinskas, K. C.

    1985-01-01

    The three-dimensional inviscid DENTON code is used to analyze flow through a radial-inflow turbine rotor. Experimental data from the rotor are compared with analytical results obtained by using the code. The experimental data available for comparison are the radial distributions of circumferentially averaged values of absolute flow angle and total pressure downstream of the rotor exit. The computed rotor-exit flow angles are generally underturned relative to the experimental values, which reflect the boundary-layer separation at the trailing edge and the development of wakes downstream of the rotor. The experimental rotor is designed for a higher-than-optimum work factor of 1.126 resulting in a nonoptimum positive incidence and causing a region of rapid flow adjustment and large velocity gradients. For this experimental rotor, the computed radial distribution of rotor-exit to turbine-inlet total pressure ratios are underpredicted due to the errors in the finite-difference approximations in the regions of rapid flow adjustment, and due to using the relatively coarser grids in the middle of the blade region where the flow passage is highly three-dimensional. Additional results obtained from the three-dimensional inviscid computation are also presented, but without comparison due to the lack of experimental data. These include quasi-secondary velocity vectors on cross-channel surfaces, velocity components on the meridional and blade-to-blade surfaces, and blade surface loading diagrams. Computed results show the evolution of a passage vortex and large streamline deviations from the computational streamwise grid lines. Experience gained from applying the code to a radial turbine geometry is also discussed.

  16. Intraocular pressure values obtained by ocular response analyzer, dynamic contour tonometry, and goldmann tonometry in keratokonic corneas.

    PubMed

    Bayer, Atilla; Sahin, Afsun; Hürmeriç, Volkan; Ozge, Gökhan

    2010-01-01

    To determine the agreement between dynamic contour tonometer (DCT), Goldmann applanation tonometer (GAT), and Ocular Response Analyzer (ORA) in keratoconic corneas and to find out the effect of corneal biomechanics on intraocular pressure (IOP) measurements obtained by these devices. IOP was measured with the ORA, DCT, and GAT in random order in 120 eyes of 61 keratoconus patients. Central corneal thickness (CCT) and keratometry were measured after all IOP determinations had been made. The mean IOP measurement by the ORA and DCT was compared with the measurement by the GAT, using Student t test. Bland-Altman analysis was performed to assess the clinical agreement between these methods. The effect of corneal hysteresis (CH), corneal resistance factor (CRF), and CCT on measured IOP was explored by multiple backward stepwise linear regression analysis. The mean±SD patient age was 30.6±11.2 years. The mean±SD IOP measurement obtained with GAT, ORA Goldmann-correlated IOP (IOPg), ORA corneal-compensated IOP (IOPcc), and DCT was 10.96±2.8, 10.23±3.5, 14.65±2.8, and 15.42±2.7 mm Hg, respectively. The mean±SD CCT was 464.08±58.4 microns. The mean difference between IOPcc and GAT (P<0.0001), IOPcc and DCT (P<0.001), GAT and DCT (P<0.0001), IOPg and GAT (P<0.002), and IOPg and DCT (P<0.0001), was highly statistically significant. In multivariable regression analysis, DCT IOP and GAT IOP measurements were significantly associated with CH and CRF (P<0.0001 for both). DCT seemed to be affected by CH and CRF, and the IOP values tended to be higher when compared with GAT. ORA-measured IOPcc was found to be independent of CCT and suitable in comparison to the DCT in keratoconic eyes.

  17. Experimental and analytical study of high velocity impact on Kevlar/Epoxy composite plates

    NASA Astrophysics Data System (ADS)

    Sikarwar, Rahul S.; Velmurugan, Raman; Madhu, Velmuri

    2012-12-01

    In the present study, impact behavior of Kevlar/Epoxy composite plates has been carried out experimentally by considering different thicknesses and lay-up sequences and compared with analytical results. The effect of thickness, lay-up sequence on energy absorbing capacity has been studied for high velocity impact. Four lay-up sequences and four thickness values have been considered. Initial velocities and residual velocities are measured experimentally to calculate the energy absorbing capacity of laminates. Residual velocity of projectile and energy absorbed by laminates are calculated analytically. The results obtained from analytical study are found to be in good agreement with experimental results. It is observed from the study that 0/90 lay-up sequence is most effective for impact resistance. Delamination area is maximum on the back side of the plate for all thickness values and lay-up sequences. The delamination area on the back is maximum for 0/90/45/-45 laminates compared to other lay-up sequences.

  18. Experimental metrology to obtain thermal phonon transmission coefficients at solid interfaces

    NASA Astrophysics Data System (ADS)

    Hua, Chengyun; Chen, Xiangwen; Ravichandran, Navaneetha K.; Minnich, Austin J.

    2017-05-01

    Interfaces play an essential role in phonon-mediated heat conduction in solids, impacting applications ranging from thermoelectric waste heat recovery to heat dissipation in electronics. From the microscopic perspective, interfacial phonon transport is described by transmission coefficients that link vibrational modes in the materials composing the interface. However, direct experimental determination of these coefficients is challenging because most experiments provide a mode-averaged interface conductance that obscures the microscopic detail. Here, we report a metrology to extract thermal phonon transmission coefficients at solid interfaces using ab initio phonon transport modeling and a thermal characterization technique, time-domain thermoreflectance. In combination with transmission electron microscopy characterization of the interface, our approach allows us to link the atomic structure of an interface to the spectral content of the heat crossing it. Our work provides a useful perspective on the microscopic processes governing interfacial heat conduction.

  19. Sulphate partitioning into calcite: Experimental verification of pH control and application to seasonality in speleothems

    NASA Astrophysics Data System (ADS)

    Wynn, Peter M.; Fairchild, Ian J.; Borsato, Andrea; Spötl, Christoph; Hartland, Adam; Baker, Andy; Frisia, Silvia; Baldini, James U. L.

    2018-04-01

    Carbonate-associated sulphate (CAS) is a useful carrier of palaeoenvironmental information throughout the geologic record, particularly through its stable isotope composition. However, a paucity of experimental data restricts quantitative understanding of sulphate incorporation into carbonates, and consequently CAS concentrations and their diagenetic modifications are rarely interpreted. However, in the case of calcite speleothems, the remarkably high-resolution CAS records which are obtainable via modern microanalytical techniques represent a potentially invaluable source of palaeoenvironmental information. Here, we describe the results of controlled experiments of sulphate co-precipitation with calcite in freshwater solutions where pH, saturation state, and sulphate concentration were varied independently of each other. Solution pH is confirmed as the principal control on sulphate incorporation into calcite. The relative efficiency of incorporation was calculated as a partition coefficient DSO4 = (mSO4/mCO3)solid/(mSO4/mCO3)solution. High crystal growth rates (driven by either pH or saturation state) encouraged higher values of DSO4 because of an increasing concentration of defect sites on crystal surfaces. At low growth rates, DSO4 was reduced due to an inferred competition between sulphate and bicarbonate at the calcite surface. These experimental results are applied to understand the incorporation of sulphate into speleothem calcite. The experimentally determined pH-dependence suggests that strong seasonal variations in cave air PCO2 could account for annual cycles in sulphate concentration observed in stalagmites. Our new experimentally determined values of DSO4 were compared with DSO4 values calculated from speleothem-drip water monitoring from two caves within the Austrian and Italian Alps. At Obir cave, Austria, DSO4 (×105) varies between 11.1 (winter) and 9.0 (summer) and the corresponding figures for Ernesto cave, Italy, are 15.4 (winter) and 14

  20. Obtaining orthotropic elasticity tensor using entries zeroing method.

    NASA Astrophysics Data System (ADS)

    Gierlach, Bartosz; Danek, Tomasz

    2017-04-01

    A generally anisotropic elasticity tensor obtained from measurements can be represented by a tensor belonging to one of eight material symmetry classes. Knowledge of symmetry class and orientation is helpful for describing physical properties of a medium. For each non-trivial symmetry class except isotropic this problem is nonlinear. A common method of obtaining effective tensor is a choosing its non-trivial symmetry class and minimizing Frobenius norm between measured and effective tensor in the same coordinate system. Global optimization algorithm has to be used to determine the best rotation of a tensor. In this contribution, we propose a new approach to obtain optimal tensor, with the assumption that it is orthotropic (or at least has a similar shape to the orthotropic one). In orthotropic form tensor 24 out of 36 entries are zeros. The idea is to minimize the sum of squared entries which are supposed to be equal to zero through rotation calculated with optimization algorithm - in this case Particle Swarm Optimization (PSO) algorithm. Quaternions were used to parametrize rotations in 3D space to improve computational efficiency. In order to avoid a choice of local minima we apply PSO several times and only if we obtain similar results for the third time we consider it as a correct value and finish computations. To analyze obtained results Monte-Carlo method was used. After thousands of single runs of PSO optimization, we obtained values of quaternion parts and plot them. Points concentrate in several points of the graph following the regular pattern. It suggests the existence of more complex symmetry in the analyzed tensor. Then thousands of realizations of generally anisotropic tensor were generated - each tensor entry was replaced with a random value drawn from normal distribution having a mean equal to measured tensor entry and standard deviation of the measurement. Each of these tensors was subject of PSO based optimization delivering quaternion for optimal

  1. Theoretical Evaluation of Crosslink Density of Chain Extended Polyurethane Networks Based on Hydroxyl Terminated Polybutadiene and Butanediol and Comparison with Experimental Data

    NASA Astrophysics Data System (ADS)

    Sekkar, Venkataraman; Alex, Ancy Smitha; Kumar, Vijendra; Bandyopadhyay, G. G.

    2018-01-01

    Polyurethane networks between hydroxyl terminated polybutadiene (HTPB) and butanediol (BD) were prepared using toluene diisocyanate (TDI) as the curative. HTPB and BD were taken at equivalent ratios viz.: 1:0, 1:1, 1:2, 1:4, and 1:8. Crosslink density (CLD) was theoretically calculated using α-model equations developed by Marsh. CLD for the polyurethane networks was experimentally evaluated from equilibrium swell and stress-strain data. Young's modulus and Mooney-Rivlin approaches were adopted to calculate CLD from stress-strain data. Experimentally obtained CLD values were enormously higher than theoretical values especially at higher BD/HTPB equivalent ratios. The difference in the theoretical and experimental values for CLD was explained in terms of local crystallization due to the formation of hard segments and hydrogen bonded interactions.

  2. A Comparison of Streaming and Microelectrophoresis Methods for Obtaining the zeta Potential of Granular Porous Media Surfaces.

    PubMed

    Johnson

    1999-01-01

    The electrokinetic behavior of granular quartz sand in aqueous solution is investigated by both microelectrophoresis and streaming potential methods. zeta potentials of surfaces composed of granular quartz obtained via streaming potential methods are compared to electrophoretic mobility zeta potential values of colloid-sized quartz fragments. The zeta values generated by these alternate methods are in close agreement over a wide pH range and electrolyte concentrations spanning several orders of magnitude. Streaming measurements performed on chemically heterogeneous mixtures of physically homogeneous sand are shown to obey a simple mixing model based on the surface area-weighted average of the streaming potentials associated with the individual end members. These experimental results support the applicability of the streaming potential method as a means of determining the zeta potential of granular porous media surfaces. Copyright 1999 Academic Press.

  3. Experimental metrology to obtain thermal phonon transmission coefficients at solid interfaces

    DOE PAGES

    Hua, Chengyun; Chen, Xiangwen; Ravichandran, Navaneetha K.; ...

    2017-05-17

    Interfaces play an essential role in phonon-mediated heat conduction in solids, impacting applications ranging from thermoelectric waste heat recovery to heat dissipation in electronics. From the microscopic perspective, interfacial phonon transport is described by transmission coefficients that link vibrational modes in the materials composing the interface. But, direct experimental determination of these coefficients is challenging because most experiments provide a mode-averaged interface conductance that obscures the microscopic detail. Here, we report a metrology to extract thermal phonon transmission coefficients at solid interfaces using ab initio phonon transport modeling and a thermal characterization technique, time-domain thermoreflectance. In combination with transmission electronmore » microscopy characterization of the interface, our approach allows us to link the atomic structure of an interface to the spectral content of the heat crossing it. This work provides a useful perspective on the microscopic processes governing interfacial heat conduction.« less

  4. Differences in liver stiffness values obtained with new ultrasound elastography machines and Fibroscan: A comparative study.

    PubMed

    Piscaglia, Fabio; Salvatore, Veronica; Mulazzani, Lorenzo; Cantisani, Vito; Colecchia, Antonio; Di Donato, Roberto; Felicani, Cristina; Ferrarini, Alessia; Gamal, Nesrine; Grasso, Valentina; Marasco, Giovanni; Mazzotta, Elena; Ravaioli, Federico; Ruggieri, Giacomo; Serio, Ilaria; Sitouok Nkamgho, Joules Fabrice; Serra, Carla; Festi, Davide; Schiavone, Cosima; Bolondi, Luigi

    2017-07-01

    Whether Fibroscan thresholds can be immediately adopted for none, some or all other shear wave elastography techniques has not been tested. The aim of the present study was to test the concordance of the findings obtained from 7 of the most recent ultrasound elastography machines with respect to Fibroscan. Sixteen hepatitis C virus-related patients with fibrosis ≥2 and having reliable results at Fibroscan were investigated in two intercostal spaces using 7 different elastography machines. Coefficients of both precision (an index of data dispersion) and accuracy (an index of bias correction factors expressing different magnitudes of changes in comparison to the reference) were calculated. Median stiffness values differed among the different machines as did coefficients of both precision (range 0.54-0.72) and accuracy (range 0.28-0.87). When the average of the measurements of two intercostal spaces was considered, coefficients of precision significantly increased with all machines (range 0.72-0.90) whereas of accuracy improved more scatteredly and by a smaller degree (range 0.40-0.99). The present results showed only moderate concordance of the majority of elastography machines with the Fibroscan results, preventing the possibility of the immediate universal adoption of Fibroscan thresholds for defining liver fibrosis staging for all new machines. Copyright © 2017 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

  5. Assessment of IgE binding to native and hydrolyzed soy protein in serum obtained from dogs with experimentally induced soy protein hypersensitivity.

    PubMed

    Serra, Montserrat; Brazís, Pilar; Fondati, Alessandra; Puigdemont, Anna

    2006-11-01

    To assess binding of IgE to native, whole hydrolyzed, and separated hydrolyzed fractions of soy protein in serum obtained from dogs with experimentally induced soy protein hypersensitivity. 8 naïve Beagles (6 experimentally sensitized to native soy protein and 2 control dogs). 6 dogs were sensitized against soy protein by administration of allergens during a 90-day period. After the sensitization protocol was completed, serum concentrations of soy-specific IgE were measured and intradermal skin tests were performed in all 6 dogs to confirm that the dogs were sensitized against soy protein. Serum samples from each sensitized and control dog underwent western blot analysis to assess the molecular mass band pattern of the different allergenic soy fractions and evaluate reactivities to native and hydrolyzed soy protein. In sera from sensitized dogs, a characteristic band pattern with 2 major bands (approx 75 and 50 kd) and 2 minor bands (approx 31 and 20 kd) was detected, whereas only a diffuse band pattern associated with whole hydrolyzed soy protein was detected in the most reactive dog. Reactivity was evident only for the higher molecular mass peptide fraction. In control dogs, no IgE reaction to native or hydrolyzed soy protein was detected. Data suggest that the binding of soy-specific IgE to the hydrolyzed soy protein used in the study was significantly reduced, compared with binding of soy-specific IgE to the native soy protein, in dogs with experimentally induced soy hypersensitivity.

  6. Measuring the subjective value of risky and ambiguous options using experimental economics and functional MRI methods.

    PubMed

    Levy, Ifat; Rosenberg Belmaker, Lior; Manson, Kirk; Tymula, Agnieszka; Glimcher, Paul W

    2012-09-19

    Most of the choices we make have uncertain consequences. In some cases the probabilities for different possible outcomes are precisely known, a condition termed "risky". In other cases when probabilities cannot be estimated, this is a condition described as "ambiguous". While most people are averse to both risk and ambiguity(1,2), the degree of those aversions vary substantially across individuals, such that the subjective value of the same risky or ambiguous option can be very different for different individuals. We combine functional MRI (fMRI) with an experimental economics-based method(3 )to assess the neural representation of the subjective values of risky and ambiguous options(4). This technique can be now used to study these neural representations in different populations, such as different age groups and different patient populations. In our experiment, subjects make consequential choices between two alternatives while their neural activation is tracked using fMRI. On each trial subjects choose between lotteries that vary in their monetary amount and in either the probability of winning that amount or the ambiguity level associated with winning. Our parametric design allows us to use each individual's choice behavior to estimate their attitudes towards risk and ambiguity, and thus to estimate the subjective values that each option held for them. Another important feature of the design is that the outcome of the chosen lottery is not revealed during the experiment, so that no learning can take place, and thus the ambiguous options remain ambiguous and risk attitudes are stable. Instead, at the end of the scanning session one or few trials are randomly selected and played for real money. Since subjects do not know beforehand which trials will be selected, they must treat each and every trial as if it and it alone was the one trial on which they will be paid. This design ensures that we can estimate the true subjective value of each option to each subject. We

  7. Uncertainties in obtaining high reliability from stress-strength models

    NASA Technical Reports Server (NTRS)

    Neal, Donald M.; Matthews, William T.; Vangel, Mark G.

    1992-01-01

    There has been a recent interest in determining high statistical reliability in risk assessment of aircraft components. The potential consequences are identified of incorrectly assuming a particular statistical distribution for stress or strength data used in obtaining the high reliability values. The computation of the reliability is defined as the probability of the strength being greater than the stress over the range of stress values. This method is often referred to as the stress-strength model. A sensitivity analysis was performed involving a comparison of reliability results in order to evaluate the effects of assuming specific statistical distributions. Both known population distributions, and those that differed slightly from the known, were considered. Results showed substantial differences in reliability estimates even for almost nondetectable differences in the assumed distributions. These differences represent a potential problem in using the stress-strength model for high reliability computations, since in practice it is impossible to ever know the exact (population) distribution. An alternative reliability computation procedure is examined involving determination of a lower bound on the reliability values using extreme value distributions. This procedure reduces the possibility of obtaining nonconservative reliability estimates. Results indicated the method can provide conservative bounds when computing high reliability. An alternative reliability computation procedure is examined involving determination of a lower bound on the reliability values using extreme value distributions. This procedure reduces the possibility of obtaining nonconservative reliability estimates. Results indicated the method can provide conservative bounds when computing high reliability.

  8. A Note on the Fractal Behavior of Hydraulic Conductivity and Effective Porosity for Experimental Values in a Confined Aquifer

    PubMed Central

    De Bartolo, Samuele; Fallico, Carmine; Veltri, Massimo

    2013-01-01

    Hydraulic conductivity and effective porosity values for the confined sandy loam aquifer of the Montalto Uffugo (Italy) test field were obtained by laboratory and field measurements; the first ones were carried out on undisturbed soil samples and the others by slug and aquifer tests. A direct simple-scaling analysis was performed for the whole range of measurement and a comparison among the different types of fractal models describing the scale behavior was made. Some indications about the largest pore size to utilize in the fractal models were given. The results obtained for a sandy loam soil show that it is possible to obtain global indications on the behavior of the hydraulic conductivity versus the porosity utilizing a simple scaling relation and a fractal model in coupled manner. PMID:24385876

  9. Experimental studies on ion mobility in xenon-trimethylamine mixtures

    NASA Astrophysics Data System (ADS)

    Trindade, A. M. F.; Encarnação, P. M. C. C.; Escada, J.; Cortez, A. F. V.; Neves, P. N. B.; Conde, C. A. N.; Borges, F. I. G. M.; Santos, F. P.

    2017-07-01

    In this paper we present experimental results for ion reduced mobilities (K0) in gaseous trimethylamine, TMA—(CH3)3N, and xenon-TMA mixtures for reduced electric fields E/N between 7.5 and 60 Td and in the pressure range from 0.5 to 10 Torr, at room temperature. Both in the mixtures and in pure TMA only one peak was observed in the time of arrival spectra, which is believed to be due to two TMA ions with similar mass, (CH3)3N+ (59 u) and (CH3)2CH2N+ (58 u), whose mobility is indistinguishable in our experimental system. The possibility of ion cluster formation is also discussed. In pure TMA, for the E/N range investigated, an average value of 0.56 cm2V-1s-1 was obtained for the reduced mobility of TMA ions. For the studied mixtures, it was observed that even a very small amount of gaseous TMA (~0.2%) in xenon leads to the production of the above referred TMA ions or clusters. The reduced mobility value of this ion or ions in Xe-TMA mixtures is higher than the value in pure TMA: around 0.8 cm2V-1s-1 for TMA concentrations from 0.2% to about 10%, decreasing for higher TMA percentages, eventually converging to the reduced mobility value in pure TMA.

  10. Net energy content of canola meal fed to growing pigs and effect of experimental methodology on energy values.

    PubMed

    Kim, J W; Koo, B; Nyachoti, C M

    2018-04-14

    An experiment was conducted to determine the digestible energy (DE), metabolizable energy (ME), and net energy (NE) contents of canola meal (CM) and to investigate the effects of basal diet [corn diet vs. corn-soybean meal (SBM) diet] and methodology (difference method vs. regression method) on energy values of CM. Thirty-six growing barrows (20.8 ± 1.0 kg initial body weight [BW]) were individually housed in metabolism crates and randomly allotted to one of six dietary treatments to give six replicates per treatment. The six experimental diets included a corn diet, a corn-SBM diet, a corn diet with 15 or 30% of CM, and a corn-SBM diet with 15 or 30% of CM. The DE, ME, and NE of CM were determined using the corn diet or the corn-SBM diet as a basal diet. In each basal diet, two additional diets containing 15 or 30% of CM were formulated to compare the determined energy values by the difference method and estimated energy values from the regression method. Feeding level was set at 550 kcal ME/kg BW0.6 per day. Pigs were fed experimental diets for 16 d including 10 d for adaptation and 6 d for total collection of feces and urine. Pigs were then moved into indirect calorimetry chambers to determine 24 h heat production (HP) and 12 h fasting HP. The DE, ME, and NE of CM determined by the difference method were within the 95% confidence intervals estimated for the DE, ME, and NE of CM by the regression method regardless of the basal diets used, which indicates that the difference and regression methods give equivalent DE, ME, and NE of CM. However, when the goodness of fit for the linear model was compared, the r2 of the regression analysis from the corn-SBM diet (0.78) was relatively greater than that from corn diet (0.40). The estimated NE of CM by the prediction equations generated by either the corn diet or corn-SBM diets were 2,096 kcal/kg and 1,960 kcal/kg (as-fed basis), respectively, whereas those values determined by the difference method were 2,233 kcal

  11. Accuracy Evaluation of the Unified P-Value from Combining Correlated P-Values

    PubMed Central

    Alves, Gelio; Yu, Yi-Kuo

    2014-01-01

    Meta-analysis methods that combine -values into a single unified -value are frequently employed to improve confidence in hypothesis testing. An assumption made by most meta-analysis methods is that the -values to be combined are independent, which may not always be true. To investigate the accuracy of the unified -value from combining correlated -values, we have evaluated a family of statistical methods that combine: independent, weighted independent, correlated, and weighted correlated -values. Statistical accuracy evaluation by combining simulated correlated -values showed that correlation among -values can have a significant effect on the accuracy of the combined -value obtained. Among the statistical methods evaluated those that weight -values compute more accurate combined -values than those that do not. Also, statistical methods that utilize the correlation information have the best performance, producing significantly more accurate combined -values. In our study we have demonstrated that statistical methods that combine -values based on the assumption of independence can produce inaccurate -values when combining correlated -values, even when the -values are only weakly correlated. Therefore, to prevent from drawing false conclusions during hypothesis testing, our study advises caution be used when interpreting the -value obtained from combining -values of unknown correlation. However, when the correlation information is available, the weighting-capable statistical method, first introduced by Brown and recently modified by Hou, seems to perform the best amongst the methods investigated. PMID:24663491

  12. An Experimental Investigation of Unsteady Thrust Augmentation Using a Speaker-Driven Jet

    NASA Technical Reports Server (NTRS)

    Paxson, Daniel E.; Wernet, Mark P.; John, Wentworth T.

    2004-01-01

    An experimental investigation is described in which a simple speaker-driven jet was used as a pulsed thrust source (driver) for an ejector configuration. The objectives of the investigation were twofold: first, to add to the experimental body of evidence showing that an unsteady thrust source, combined with a properly sized ejector generally yields higher thrust augmentation values than a similarly sized, steady driver of equivalent thrust. Second, to identify characteristics of the unsteady driver that may be useful for sizing ejectors, and predicting what thrust augmentation values may be achieved. The speaker-driven jet provided a convenient source for the investigation because it is entirely unsteady (having no mean component) and because relevant parameters such as frequency, time-averaged thrust, and diameter are easily variable. The experimental setup will be described, as will the various measurements made. These include both thrust and Digital Particle Imaging Velocimetry of the driver. It will be shown that thrust augmentation values as high as 1.8 were obtained, that the diameter of the best ejector scaled with the dimensions of the emitted vortex, and that the so-called Formation Number serves as a useful dimensionless number by which to characterize the jet and predict performance.

  13. Influence of premium versus value brand names on the smoking experience in a plain packaging environment: an experimental study

    PubMed Central

    Skaczkowski, Gemma; Durkin, Sarah; Kashima, Yoshihisa; Wakefield, Melanie

    2017-01-01

    Objective To examine the effect of branding, as indicated by brand name, on evaluation of the cigarette smoking experience. Design Between-subjects and within-subjects experimental study. Participants were randomly allocated to smoke a cigarette from a pack featuring a premium brand name and a cigarette from a pack featuring a value brand name. Within each condition, participants unknowingly smoked two identical cigarettes (either two premium or two value cigarettes). Setting Australia, October 2014, 2 years after tobacco plain packaging implementation. Participants 81 current cigarette smokers aged 19–39 years. From apparently premium and value brand-name packs, 40 smokers were allocated to smoke the same actual premium cigarettes and 41 were allocated to smoke the same actual value cigarettes. Primary outcome measures Experienced taste (flavour, satisfaction, enjoyment, quality, liking, mouthfeel and aftertaste), harshness, dryness, staleness, harm/strength measures (strength, tar, lightness, volume of smoke), draw effort and purchase intent. Results Cigarettes given a premium brand name were rated as having a better taste, were less harsh and less dry than identical cigarettes given a value brand name. This pattern was observed irrespective of whether the two packs actually contained premium or value cigarettes. These effects were specific: the brand name did not influence ratings of cigarette variant attributes (strength, tar, volume of smoke, lightness and draw effort). Conclusions Despite the belief that brand names represent genuine differences between cigarette products, the results suggest that at least some of this perceived sensory difference is attributable to brand image. PMID:28093441

  14. A sEMG model with experimentally based simulation parameters.

    PubMed

    Wheeler, Katherine A; Shimada, Hiroshima; Kumar, Dinesh K; Arjunan, Sridhar P

    2010-01-01

    A differential, time-invariant, surface electromyogram (sEMG) model has been implemented. While it is based on existing EMG models, the novelty of this implementation is that it assigns more accurate distributions of variables to create realistic motor unit (MU) characteristics. Variables such as muscle fibre conduction velocity, jitter (the change in the interpulse interval between subsequent action potential firings) and motor unit size have been considered to follow normal distributions about an experimentally obtained mean. In addition, motor unit firing frequencies have been considered to have non-linear and type based distributions that are in accordance with experimental results. Motor unit recruitment thresholds have been considered to be related to the MU type. The model has been used to simulate single channel differential sEMG signals from voluntary, isometric contractions of the biceps brachii muscle. The model has been experimentally verified by conducting experiments on three subjects. Comparison between simulated signals and experimental recordings shows that the Root Mean Square (RMS) increases linearly with force in both cases. The simulated signals also show similar values and rates of change of RMS to the experimental signals.

  15. Sorption and biodegradation of sulfonamide antibiotics by activated sludge: experimental assessment using batch data obtained under aerobic conditions.

    PubMed

    Yang, Sheng-Fu; Lin, Cheng-Fang; Lin, Angela Yu-Chen; Hong, Pui-Kwan Andy

    2011-05-01

    This study investigated the adsorption, desorption, and biodegradation characteristics of sulfonamide antibiotics in the presence of activated sludge with and without being subjected to NaN(3) biocide. Batch experiments were conducted and the relative contributions of adsorption and biodegradation to the observed removal of sulfonamide antibiotics were determined. Three sulfonamide antibiotics including sulfamethoxazole (SMX), sulfadimethoxine (SDM), and sulfamonomethoxine (SMM), which had been detected in the influent and the activated sludge of wastewater treatment plants (WWTP) in Taiwan, were selected for this study. Experimental results showed that the antibiotic compounds were removed via sorption and biodegradation by the activated sludge, though biodegradation was inhibited in the first 12 h possibly due to competitive inhibition of xenobiotic oxidation by readily biodegradable substances. The affinity of sulfonamides to sterilized sludge was in the order of SDM > SMM > SMX. The sulfonamides existed predominantly as anions at the study pH of 6.8, which resulted in a low level of adsorption to the activated sludge. The adsorption/desorption isotherms were of a linear form, as well described by the Freundlich isotherm with the n value approximating unity. The linear distribution coefficients (K(d)) were determined from batch equilibrium experiments with values of 28.6 ± 1.9, 55.7 ± 2.2, and 110.0 ± 4.6 mL/g for SMX, SMM, and SDM, respectively. SMX, SMM, and SDM desorb reversibly from the activated sludge leaving behind on the solids 0.9%, 1.6%, and 5.2% of the original sorption dose of 100 μg/L. The sorbed antibiotics can be introduced into the environment if no further treatments were employed to remove them from the biomass. Copyright © 2011 Elsevier Ltd. All rights reserved.

  16. Experimental study and FEM simulation of the simple shear test of cylindrical rods

    NASA Astrophysics Data System (ADS)

    Wirti, Pedro H. B.; Costa, André L. M.; Misiolek, Wojciech Z.; Valberg, Henry S.

    2018-05-01

    In the presented work an experimental simple shear device for cutting cylindrical rods was used to obtain force-displacement data for a low-carbon steel. In addition, and FEM 3D-simulation was applied to obtain internal shear stress and strain maps for this material. The experimental longitudinal grid patterns and force-displacement curve were compared with numerical simulation results. Many aspects of the elastic and plastic deformations were described. It was found that bending reduces the shear yield stress of the rod material. Shearing starts on top and bottom die-workpiece contact lines evolving in an arc-shaped area. Due to this geometry, stress concentrates on the surface of the rod until the level of damage reaches the critical value and the fracture starts here. The volume of material in the plastic zone subjected to shearing stress has a very complex shape and is function of a dimensionless geometrical parameter. Expressions to calculate the true shear stress τ and strain γ from the experimental force-displacement data were proposed. The equations' constants are determined by fitting the experimental curve with the stress τ and strain γ simulation point tracked data.

  17. Experimental determination of the x-ray atomic fundamental parameters of nickel

    NASA Astrophysics Data System (ADS)

    Ménesguen, Y.; Lépy, M.-C.; Hönicke, P.; Müller, M.; Unterumsberger, R.; Beckhoff, B.; Hoszowska, J.; Dousse, J.-Cl; Błachucki, W.; Ito, Y.; Yamashita, M.; Fukushima, S.

    2018-02-01

    The x-ray atomic properties of nickel (Ni) were investigated in a unique approach combining different experimental techniques to obtain new, useful and reliable values of atomic fundamental parameters for x-ray spectrometric purposes and for comparison with theoretical predictions. We determined the mass attenuation coefficients in an energy range covering the L- and K-absorption edges, the K-shell fluorescence yield and the Kβ/Kα and Kβ1, 3/Kα1, 2 transition probability ratios. The obtained line profiles and linewidths of the Kα and Kβ transitions in Ni can be considered as the contribution of the satellite lines arising from the [KM] shake processes suggested by Deutsch et al (1995 Phys. Rev. A 51 283) and Ito et al (2016 Phys. Rev. A 94 042506). Comparison of the new data with several databases showed good agreement, but also discrepancies were found with existing tabulated values.

  18. High-Area-Ratio Rocket Nozzle at High Combustion Chamber Pressure: Experimental and Analytical Validation

    NASA Technical Reports Server (NTRS)

    Jankovsky, Robert S.; Smith, Timothy D.; Pavli, Albert J.

    1999-01-01

    Experimental data were obtained on an optimally contoured nozzle with an area ratio of 1025:1 and on a truncated version of this nozzle with an area ratio of 440:1. The nozzles were tested with gaseous hydrogen and liquid oxygen propellants at combustion chamber pressures of 1800 to 2400 psia and mixture ratios of 3.89 to 6.15. This report compares the experimental performance, heat transfer, and boundary layer total pressure measurements with theoretical predictions of the current Joint Army, Navy, NASA, Air Force (JANNAF) developed methodology. This methodology makes use of the Two-Dimensional Kinetics (TDK) nozzle performance code. Comparisons of the TDK-predicted performance to experimentally attained thrust performance indicated that both the vacuum thrust coefficient and the vacuum specific impulse values were approximately 2.0-percent higher than the turbulent prediction for the 1025:1 configurations, and approximately 0.25-percent higher than the turbulent prediction for the 440:1 configuration. Nozzle wall temperatures were measured on the outside of a thin-walled heat sink nozzle during the test fittings. Nozzle heat fluxes were calculated front the time histories of these temperatures and compared with predictions made with the TDK code. The heat flux values were overpredicted for all cases. The results range from nearly 100 percent at an area ratio of 50 to only approximately 3 percent at an area ratio of 975. Values of the integral of the heat flux as a function of nozzle surface area were also calculated. Comparisons of the experiment with analyses of the heat flux and the heat rate per axial length also show that the experimental values were lower than the predicted value. Three boundary layer rakes mounted on the nozzle exit were used for boundary layer measurements. This arrangement allowed total pressure measurements to be obtained at 14 different distances from the nozzle wall. A comparison of boundary layer total pressure profiles and analytical

  19. Time-oriented experimental design method to optimize hydrophilic matrix formulations with gelation kinetics and drug release profiles.

    PubMed

    Shin, Sangmun; Choi, Du Hyung; Truong, Nguyen Khoa Viet; Kim, Nam Ah; Chu, Kyung Rok; Jeong, Seong Hoon

    2011-04-04

    A new experimental design methodology was developed by integrating the response surface methodology and the time series modeling. The major purposes were to identify significant factors in determining swelling and release rate from matrix tablets and their relative factor levels for optimizing the experimental responses. Properties of tablet swelling and drug release were assessed with ten factors and two default factors, a hydrophilic model drug (terazosin) and magnesium stearate, and compared with target values. The selected input control factors were arranged in a mixture simplex lattice design with 21 experimental runs. The obtained optimal settings for gelation were PEO, LH-11, Syloid, and Pharmacoat with weight ratios of 215.33 (88.50%), 5.68 (2.33%), 19.27 (7.92%), and 3.04 (1.25%), respectively. The optimal settings for drug release were PEO and citric acid with weight ratios of 191.99 (78.91%) and 51.32 (21.09%), respectively. Based on the results of matrix swelling and drug release, the optimal solutions, target values, and validation experiment results over time were similar and showed consistent patterns with very small biases. The experimental design methodology could be a very promising experimental design method to obtain maximum information with limited time and resources. It could also be very useful in formulation studies by providing a systematic and reliable screening method to characterize significant factors in the sustained release matrix tablet. Copyright © 2011 Elsevier B.V. All rights reserved.

  20. [Physical activity and respiratory function: corporal composition and spirometric values analysis].

    PubMed

    Paulo, Rui; Petrica, João; Martins, Júlio

    2013-01-01

    The main aim of this research project was to measure the effects of physical activity on corporal composition (BMI and waist circumference) on spirometric values and relate these indicators to the respiratory/ventilator function. The sample consisted of 86 individuals, higher education students, with an average age of 21.3 ± 2.4 years, who were divided into two groups: the control group consisted of 28 sedentary subjects (20.9 ± 1.3 years), and the experimental group consisting of 58 subjects (21.5 ± 2.8 years) who undertook supervised exercise. To characterize the sample of the type of physical activity, we used an adaptation of the questionnaire Telama et al.19 We assessed the value of spirometry (PEF, FVC and FEV₁) with a Microquark Cosmed spirometer and the BMI and waist circumference. The figures obtained were processed with the S.P.S.S. 19.0, the t-test, the Levene test, the Mann-Whitney test and the Spearman correlation test, adopting a significance level of 5%. The experimental group achieved significantly better BMI and waist circumference results (p = 0.05) and in all of the values assessed by spirometry (PEF, FVC and FEV₁) compared to the control group. We also found that there is a tendency for a negative correlation between the values of body composition and spirometric values, only observable in some variables (PEF, FEV₁), i.e., the higher the values of body composition, the lower the spirometric values. The students that performed supervised exercise had higher levels of body composition and lung function. Poor BMI and waist circumference values may lead to respiratory dysfunction in terms of ventilation and the respective lung volumes, limiting the practice of physical activity and increasing the probability of respiratory pathologies.

  1. Influence of premium versus value brand names on the smoking experience in a plain packaging environment: an experimental study.

    PubMed

    Skaczkowski, Gemma; Durkin, Sarah; Kashima, Yoshihisa; Wakefield, Melanie

    2017-01-16

    To examine the effect of branding, as indicated by brand name, on evaluation of the cigarette smoking experience. Between-subjects and within-subjects experimental study. Participants were randomly allocated to smoke a cigarette from a pack featuring a premium brand name and a cigarette from a pack featuring a value brand name. Within each condition, participants unknowingly smoked two identical cigarettes (either two premium or two value cigarettes). Australia, October 2014, 2 years after tobacco plain packaging implementation. 81 current cigarette smokers aged 19-39 years. From apparently premium and value brand-name packs, 40 smokers were allocated to smoke the same actual premium cigarettes and 41 were allocated to smoke the same actual value cigarettes. Experienced taste (flavour, satisfaction, enjoyment, quality, liking, mouthfeel and aftertaste), harshness, dryness, staleness, harm/strength measures (strength, tar, lightness, volume of smoke), draw effort and purchase intent. Cigarettes given a premium brand name were rated as having a better taste, were less harsh and less dry than identical cigarettes given a value brand name. This pattern was observed irrespective of whether the two packs actually contained premium or value cigarettes. These effects were specific: the brand name did not influence ratings of cigarette variant attributes (strength, tar, volume of smoke, lightness and draw effort). Despite the belief that brand names represent genuine differences between cigarette products, the results suggest that at least some of this perceived sensory difference is attributable to brand image. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  2. A framework for interval-valued information system

    NASA Astrophysics Data System (ADS)

    Yin, Yunfei; Gong, Guanghong; Han, Liang

    2012-09-01

    Interval-valued information system is used to transform the conventional dataset into the interval-valued form. To conduct the interval-valued data mining, we conduct two investigations: (1) construct the interval-valued information system, and (2) conduct the interval-valued knowledge discovery. In constructing the interval-valued information system, we first make the paired attributes in the database discovered, and then, make them stored in the neighbour locations in a common database and regard them as 'one' new field. In conducting the interval-valued knowledge discovery, we utilise some related priori knowledge and regard the priori knowledge as the control objectives; and design an approximate closed-loop control mining system. On the implemented experimental platform (prototype), we conduct the corresponding experiments and compare the proposed algorithms with several typical algorithms, such as the Apriori algorithm, the FP-growth algorithm and the CLOSE+ algorithm. The experimental results show that the interval-valued information system method is more effective than the conventional algorithms in discovering interval-valued patterns.

  3. Absolute configurations of phytotoxins seiricardine A and inuloxin A obtained by chiroptical studies.

    PubMed

    Santoro, Ernesto; Mazzeo, Giuseppe; Petrovic, Ana G; Cimmino, Alessio; Koshoubu, Jun; Evidente, Antonio; Berova, Nina; Superchi, Stefano

    2015-08-01

    The absolute configuration (AC) of the plant phytotoxin inuloxin A, produced by Inula viscosa, and of the fungal phytotoxin seiricardine A, obtained from Seiridium fungi, pathogen for cypress, has been determined by experimental measurements and theoretical simulations of chiroptical properties of three related methods, namely, Optical Rotatory Dispersion (ORD), Electronic Circular Dichroism (ECD), and Vibrational Circular Dichroism (VCD). Computational prediction by Density Functional Theory (DFT) of VCD spectra and by Time-dependent DFT (TDDFT) of ORD and ECD spectra allowed to assign (7R,8R,10S) AC to naturally occurring (+)-inuloxin A. In the case of compound (-)-seiricardine A, which lacks useful for the analysis UV-Vis absorption, and thus provides a hardly detectable ECD spectrum and quite low ORD values, an introduction of a suitable chromophore by chemical derivatization was performed. The corresponding derivative, 2-O-p-bromobenzoate ester, gave rise to an intense ECD spectrum and higher ORD and VCD values. The comparison of computed spectra with the experimental ones allowed to assign (1S,2R,3aS,4S,5R,7aS) AC to (-)-2-O-p-bromobenzoate ester of seiricardine A and then to (-)-seiricardine A. This study further supports a recent trend of concerted application of more than a single chiroptical technique toward an unambiguous assignment of AC of flexible and complex natural products. Moreover, the use of chemical derivatization, with insertion of suitable chromophoric moieties has allowed to treat also UV-Vis transparent molecules by ECD and ORD spectroscopies. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Proposed method to estimate the liquid-vapor accommodation coefficient based on experimental sonoluminescence data.

    PubMed

    Puente, Gabriela F; Bonetto, Fabián J

    2005-05-01

    We used the temporal evolution of the bubble radius in single-bubble sonoluminescence to estimate the water liquid-vapor accommodation coefficient. The rapid changes in the bubble radius that occur during the bubble collapse and rebounds are a function of the actual value of the accommodation coefficient. We selected bubble radius measurements obtained from two different experimental techniques in conjunction with a robust parameter estimation strategy and we obtained that for water at room temperature the mass accommodation coefficient is in the confidence interval [0.217,0.329].

  5. A comparison of empirical and experimental O7+, O8+, and O/H values, with applications to terrestrial solar wind charge exchange

    NASA Astrophysics Data System (ADS)

    Whittaker, Ian C.; Sembay, Steve

    2016-07-01

    Solar wind charge exchange occurs at Earth between the neutral planetary exosphere and highly charged ions of the solar wind. The main challenge in predicting the resultant photon flux in the X-ray energy bands is due to the interaction efficiency, known as the α value. This study produces experimental α values at the Earth, for oxygen emission in the range of 0.5-0.7 keV. Thirteen years of data from the Advanced Composition Explorer are examined, comparing O7+ and O8+ abundances, as well as O/H to other solar wind parameters allowing all parameters in the αO7,8+ calculation to be estimated based on solar wind velocity. Finally, a table is produced for a range of solar wind speeds giving average O7+ and O8+ abundances, O/H, and αO7,8+ values.

  6. Power laws and extreme values in antibody repertoires

    NASA Astrophysics Data System (ADS)

    Boyer, Sebastien; Biswas, Dipanwita; Scaramozzino, Natale; Kumar, Ananda Soshee; Nizak, Clément; Rivoire, Olivier

    2015-03-01

    Evolution by natural selection involves the succession of three steps: mutations, selection and proliferation. We are interested in describing and characterizing the result of selection over a population of many variants. After selection, this population will be dominated by the few best variants, with highest propensity to be selected, or highest ``selectivity.'' We ask the following question: how is the selectivity of the best variants distributed in the population? Extreme value theory, which characterizes the extreme tail of probability distributions in terms of a few universality class, has been proposed to describe it. To test this proposition and identify the relevant universality class, we performed quantitative in vitro experimental selections of libraries of >105 antibodies using the technique of phage display. Data obtained by high-throughput sequencing allows us to fit the selectivity distribution over more than two decades. In most experiments, the results show a striking power law for the selectivity distribution of the top antibodies, consistent with extreme value theory.

  7. Experimental Values of the Surface Tension of Supercooled Water

    NASA Technical Reports Server (NTRS)

    Hacker, P. T.

    1951-01-01

    The results of surface-tension measurements for supercooled water are presented. A total of 702 individual measurements of surface tension of triple-distilled water were made in the temperature range, 27 to -22.2 C, with 404 of these measurements at temperatures below 0 C. The increase in magnitude of surface tension with decreasing temperature, as indicated by measurements above 0 C, continues to -22.2 C. The inflection point in the surface-tension - temperature relation in the vicinity of 0 C, as indicated by the International Critical Table values for temperatures down to -8 C, is substantiated by the measurements in the temperature range, 0 to -22.2 C. The surface tension increases at approximately a linear rate from a value of 76.96+/-0.06 dynes per centimeter at -8 C to 79.67+/-0.06 dynes per centimeter at -22.2 C.

  8. Limit case analysis of the "stable indenter velocity" method for obtaining creep stress exponents from constant load indentation creep tests

    NASA Astrophysics Data System (ADS)

    Campbell, J.; Dean, J.; Clyne, T. W.

    2017-02-01

    This study concerns a commonly-used procedure for evaluating the steady state creep stress exponent, n, from indentation data. The procedure involves monitoring the indenter displacement history under constant load and making the assumption that, once its velocity has stabilised, the system is in a quasi-steady state, with stage II creep dominating the behaviour. The stress and strain fields under the indenter are represented by "equivalent stress" and "equivalent strain rate" values. The estimate of n is then obtained as the gradient of a plot of the logarithm of the equivalent strain rate against the logarithm of the equivalent stress. Concerns have, however, been expressed about the reliability of this procedure, and indeed it has already been shown to be fundamentally flawed. In the present paper, it is demonstrated, using a very simple analysis, that, for a genuinely stable velocity, the procedure always leads to the same, constant value for n (either 1.0 or 0.5, depending on whether the tip shape is spherical or self-similar). This occurs irrespective of the value of the measured velocity, or indeed of any creep characteristic of the material. It is now clear that previously-measured values of n, obtained using this procedure, have varied in a more or less random fashion, depending on the functional form chosen to represent the displacement-time history and the experimental variables (tip shape and size, penetration depth, etc.), with little or no sensitivity to the true value of n.

  9. Experimental research of thermal loading of the rocket payload fairing element during the atmospheric phase of the descent trajectory

    NASA Astrophysics Data System (ADS)

    Trushlyakov, V.; Iordan, Yu; Davydovich, D.; Zharikov, K.; Dron, M.

    2018-01-01

    The thermal loading physical simulation in the experimental wind tunnel on the design element of the payload fairing made of carbon fiber was done. The experimental study is given in the speed range below 70 m/s, which corresponds to the interval of heights of the descent trajectory of the payload fairing half below 10 km. The values of heat transfer coefficient are obtained. The analysis of the results is carried out.

  10. Thermal Effusivity of Vegetable Oils Obtained by a Photothermal Technique

    NASA Astrophysics Data System (ADS)

    Cervantes-Espinosa, L. M.; de L. Castillo-Alvarado, F.; Lara-Hernández, G.; Cruz-Orea, A.; Hernández-Aguilar, C.; Domínguez-Pacheco, A.

    2014-10-01

    Thermal properties of several vegetable oils such as soy, corn, and avocado commercial oils were obtained by using a photopyroelectric technique. The inverse photopyroelectric configuration was used in order to obtain the thermal effusivity of the oil samples. The theoretical equation for the photopyroelectric signal in this configuration, as a function of the incident light modulation frequency, was fitted to the experimental data in order to obtain the thermal effusivity of these samples. The obtained results are in good agreement with the thermal effusivity reported for other vegetable oils. All measurements were done at room temperature.

  11. Potential Values of Incorporating a Multiple-Choice Question Construction in Physics Experimentation Instruction

    NASA Astrophysics Data System (ADS)

    Yu, Fu-Yun; Liu, Yu-Hsin

    2005-09-01

    The potential value of a multiple-choice question-construction instructional strategy for the support of students’ learning of physics experiments was examined in the study. Forty-two university freshmen participated in the study for a whole semester. A constant comparison method adopted to categorize students’ qualitative data indicated that the influences of multiple-choice question construction were evident in several significant ways (promoting constructive and productive studying habits; reflecting and previewing course-related materials; increasing in-group communication and interaction; breaking passive learning style and habits, etc.), which, worked together, not only enhanced students’ comprehension and retention of the obtained knowledge, but also helped distil a sense of empowerment and learning community within the participants. Analysis with one-group t-tests, using 3 as the expected mean, on quantitative data further found that students’ satisfaction toward past learning experience, and perceptions toward this strategy’s potentials for promoting learning were statistically significant at the 0.0005 level, while learning anxiety was not statistically significant. Suggestions for incorporating question-generation activities within classroom and topics for future studies were rendered.

  12. Effects of an exercise program on blood biochemical values and exercise stage of chronic kidney disease patients.

    PubMed

    Chen, Pei-Ying; Huang, Yi-Ching; Kao, Yu-Hsiu; Chen, Jinn-Yang

    2010-06-01

    Chronic kidney disease (CKD) patients face a relatively high risk of cardiovascular disease morbidity and mortality. A healthy lifestyle facilitated by participation in a regular exercise regimen may prevent or retard conditions commonly associated with CKD, including hypertension, hyperlipidemia, and diabetes. This study examined the effect of a tailored exercise program on blood biochemical values and other exercise-related variables in CKD patients. A total of 94 subjects diagnosed with CKD by a nephrology outpatient clinic at a medical center in northern Taiwan participated in this quasi-experimental study. Subjects were randomly divided into an experimental group (n = 45) or a control group (n = 49). Experimental group subjects agreed to join a 3-month exercise program. Individual guidance was given remotely to the experimental group over the telephone during the second and the third months following initiation of the exercise intervention. Both groups completed the pretest and posttest forms of the Stages of Exercise Questionnaire, and blood biochemical data were obtained from patient medical files. Data were analyzed using analysis of covariance. The preexercise cholesterol values (from 198.03 +/- 43.52 to 160.97 +/- 37.39 mg/dl) of the experimental group differed significantly from their postexercise values. Also, the number of subjects in the experimental group who reported exercising regularly rose from 57.8% pretest to 75.6% posttest. However, changes in red blood cell count, hemoglobin, hematocrit, and blood sugar were all insignificant in the experimental group. No significant change in any of these items was detected in the control group. The cholesterol value of the experimental group (158.75 mg/dl) was significantly lower than that of the control group (177.29 mg/dl) after applying analysis of covariance, using the pretest results of both groups as the covariate. The developed exercise program was found to reduce cholesterol levels in CKD patients

  13. Quantum Experimental Data in Psychology and Economics

    NASA Astrophysics Data System (ADS)

    Aerts, Diederik; D'Hooghe, Bart; Haven, Emmanuel

    2010-12-01

    We prove a theorem which shows that a collection of experimental data of probabilistic weights related to decisions with respect to situations and their disjunction cannot be modeled within a classical probabilistic weight structure in case the experimental data contain the effect referred to as the ‘disjunction effect’ in psychology. We identify different experimental situations in psychology, more specifically in concept theory and in decision theory, and in economics (namely situations where Savage’s Sure-Thing Principle is violated) where the disjunction effect appears and we point out the common nature of the effect. We analyze how our theorem constitutes a no-go theorem for classical probabilistic weight structures for common experimental data when the disjunction effect is affecting the values of these data. We put forward a simple geometric criterion that reveals the non classicality of the considered probabilistic weights and we illustrate our geometrical criterion by means of experimentally measured membership weights of items with respect to pairs of concepts and their disjunctions. The violation of the classical probabilistic weight structure is very analogous to the violation of the well-known Bell inequalities studied in quantum mechanics. The no-go theorem we prove in the present article with respect to the collection of experimental data we consider has a status analogous to the well known no-go theorems for hidden variable theories in quantum mechanics with respect to experimental data obtained in quantum laboratories. Our analysis puts forward a strong argument in favor of the validity of using the quantum formalism for modeling the considered psychological experimental data as considered in this paper.

  14. Attitudes toward older adults: A matter of cultural values or personal values?

    PubMed

    Zhang, Xin; Xing, Cai; Guan, Yanjun; Song, Xuan; Melloy, Robert; Wang, Fei; Jin, Xiaoyu

    2016-02-01

    The current research aimed to address the inconsistent findings regarding cultural differences in attitudes toward older adults by differentiating the effects of personal and cultural values. In Study 1, we used data from the sixth wave of the World Values Survey to examine attitudes toward older adults across cultures, and how different personal values (i.e., communal vs. agentic) and cultural values (i.e., individualism) predicted these attitudes. The results of hierarchical linear modeling analyses showed that after controlling for potential covariates, personal communal values positively correlated with positive attitudes toward older adults; however, cultural individualistic values did not. To further examine the causal effects of personal values (vs. cultural values), we conducted an experimental study and confirmed that priming personal values rather than cultural values had significant effects on ageism attitudes. The present studies help to reconcile conflicting results on cultural differences in attitudes toward older adults. (c) 2016 APA, all rights reserved).

  15. Characterisation of transition state structures for protein folding using ‘high’, ‘medium’ and ‘low’ Φ-values

    PubMed Central

    Geierhaas, Christian D.; Salvatella, Xavier; Clarke, Jane; Vendruscolo, Michele

    2008-01-01

    It has been suggested that Φ-values, which allow structural information about transition states (TSs) for protein folding to be obtained, are most reliably interpreted when divided into three classes (high, medium and low). High Φ-values indicate almost completely folded regions in the TS, intermediate Φ-values regions with a detectable amount of structure and low Φ-values indicate mostly unstructured regions. To explore the extent to which this classification can be used to characterise in detail the structure of TSs for protein folding, we used Φ-values divided into these classes as restraints in molecular dynamics simulations. This type of procedure is related to that used in NMR spectroscopy to define the structure of native proteins from the measurement of inter-proton distances derived from nuclear Overhauser effects. We illustrate this approach by determining the TS ensembles of five proteins and by showing that the results are similar to those obtained by using as restraints the actual numerical Φ-values measured experimentally. Our results indicate that the simultaneous consideration of a set of low-resolution Φ-values can provide sufficient information for characterising the architecture of a TS for folding of a protein. PMID:18299294

  16. True detection limits in an experimental linearly heteroscedastic system. Part 1

    NASA Astrophysics Data System (ADS)

    Voigtman, Edward; Abraham, Kevin T.

    2011-11-01

    Using a lab-constructed laser-excited filter fluorimeter deliberately designed to exhibit linearly heteroscedastic, additive Gaussian noise, it has been shown that accurate estimates may be made of the true theoretical Currie decision levels ( YC and XC) and true Currie detection limits ( YD and XD) for the detection of rhodamine 6 G tetrafluoroborate in ethanol. The obtained experimental values, for 5% probability of false positives and 5% probability of false negatives, were YC = 56.1 mV, YD = 125. mV, XC = 0.132 μg /mL and XD = 0.294 μg /mL. For 5% probability of false positives and 1% probability of false negatives, the obtained detection limits were YD = 158. mV and XD = 0.372 μg /mL. These decision levels and corresponding detection limits were shown to pass the ultimate test: they resulted in observed probabilities of false positives and false negatives that were statistically equivalent to the a priori specified values.

  17. Experimental design for the evaluation of struvite sedimentation obtained from an ammonium concentrated wastewater.

    PubMed

    Castro, Samuel Rodrigues; Araújo, Mahira Adna Cota; Lange, Liséte Celina

    2013-01-01

    Chemical precipitation of struvite as a technique of ammonium nitrogen (NH(4)-N) removal from concentrated wastewater has been shown to be an attractive alternative due to its high effectiveness, reaction rate, simplicity, environmental sustainability and, especially, the application potential of the generated solids for the fertilizer industry. The technique of experimental design has been used in order to identify and evaluate the optimum conditions of chemical precipitation reaction applied in a struvite sedimentation study. The preliminary tests were performed using synthetic effluent with a concentration equal to 500.0 mg N L(-1). The stoichiometric ratio Mg:NH(4):PO(4) equal to 1.5:1.0:1.25 and pH equal to 8.5 were taken to be the optimum conditions, where a NH(4)-N removal equal to 98.6% was achieved with only 10-min reaction time. This condition has been used to evaluate the struvite sedimentation from synthetic wastewaters, intending to check the optimum conditions achieved by the experimental design in different initial concentrations, 1,000 and 2,000 mg N L(-1). The results were typical of a good zonal sedimentation and can be used in the scale up the system.

  18. Studies of obtaining and stability in aqueous medium of new complex compounds of Ti(IV) and Zr(IV) used in ecological leather tanning

    NASA Astrophysics Data System (ADS)

    Crudu, Marian; Sibiescu, Doina; Rosca, Ioan; Sutiman, Daniel; Vizitiu, Mihaela

    2009-01-01

    In this paper, the study of obtaining new coordination compounds of Ti(IV) and Zr(IV) using as ligand: D,L-β-iso-butyric acid, is presented. Also, the stability of these compounds in aqueous medium is studied. The studies of obtaining and of stability of the new compounds were accomplished in aqueous solutions using methods characteristic for coordination compounds: conductance and pH measurements. The combination ratios and the stability were determined with methods characteristic for studies in solutions. From experimental data resulted that the combination ratio of central metallic atoms with the ligand derived from D,L-β-iso-butyric acid was 1:2. From experimental data resulted that in strong acid and strong basic mediums, the coordination compounds could not be obtained. The optimal stability of the studied compounds is limited between 3-6, pH - values. This fact is in accordance with the conditions of using these compounds in ecological leather tanning. Of great importance is that these compounds were used with very good results in tanning processes of different types of leather. This fact evidenced that the ecological alternative of tanning is better than non-ecological tanning using chrome compounds. The importance of this paper consists in obtaining new coordination compounds that can be used in ecological leather tanning.

  19. Binding Energies of Proton-Bound Dimers of Imidazole and n-Acetylalanine Methyl Ester Obtained by Blackbody Infrared Radiative Dissociation

    PubMed Central

    Jockusch, Rebecca A.; Williams*, Evan R.

    2005-01-01

    The dissociation kinetics of protonated n-acetyl-L-alanine methyl ester dimer (AcAlaMEd), imidazole dimer, and their cross dimer were measured using blackbody infrared radiative dissociation (BIRD). Master equation modeling of these data was used to extract threshold dissociation energies (Eo) for the dimers. Values of 1.18 ± 0.06, 1.11 ± 0.04, and 1.12 ± 0.08 eV were obtained for AcAlaMEd, imidazole dimer, and the cross dimer, respectively. Assuming that the reverse activation barrier for dissociation of the ion–molecule complex is negligible, the value of Eo can be compared to the dissociation enthalpy (ΔHd°) from HPMS data. The Eo values obtained for the imidazole dimer and the cross dimer are in agreement with HPMS values; the value for AcAlaMEd is somewhat lower. Radiative rate constants used in the master equation modeling were determined using transition dipole moments calculated at the semiempirical (AM1) level for all dimers and compared to ab initio (RHF/3-21G*) calculations where possible. To reproduce the experimentally measured dissociation rates using master equation modeling, it was necessary to multiply semiempirical transition dipole moments by a factor between 2 and 3. Values for transition dipole moments from the ab initio calculations could be used for two of the dimers but appear to be too low for AcAlaMEd. These results demonstrate that BIRD, in combination with master equation modeling, can be used to determine threshold dissociation energies for intermediate size ions that are in neither the truncated Boltzmann nor the rapid energy exchange limit. PMID:16604163

  20. 21 CFR 170.17 - Exemption for investigational use and procedure for obtaining authorization to market edible...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Exemption for investigational use and procedure for obtaining authorization to market edible products from experimental animals. 170.17 Section 170.17 Food and... procedure for obtaining authorization to market edible products from experimental animals. A food additive...

  1. In Vivo Efficacy of Gum Obtained Pistacia Atlantica in Experimental Treatment of Cutaneous Leishmaniasis

    PubMed Central

    Taran, M; Mohebali, M; Esmaeli, J

    2010-01-01

    Background: Recent circumstantial evidences are suggesting that an increasing number of Iranian patients with cutaneous leishmaniasis are unresponsive to meglumine antimoniate (Glucantime®). Pistacia atlantica is native plant in Iran (central, western, and eastern regions). Gum obtained Pistacia atlantica has been reported to possess considerable in vitro antimicrobial activity. In this study, we aimed to investigate antileishmanial activity of P. atlantica. Methods Male BALB/c mice were inoculated subcutaneously 2×106 L. major Promastigotes (MHROM/IR/75/ER) at the base of tail in 2007. Mice were randomly divided into 3 groups. in group 1 Glucantime® was administered to the BALB/c mice in regimen of 60 mg per kg of body weight for 28 days by intraperitoneal injections per day, in group 2 the gum of P. atlantica var. Kurdica were tested by rubbing of local lesions for 28 days, group 3 infected but non-treated. Comparisons of treated groups and untreated group were done by two-way analysis of variance (ANOVA) Results Topically rubbing administration of gum obtained P. atlantica var. kurdica daily for 28 days like Glucantime® decreased skin lesion size in the BALB/c mice infected with L. major compared with that in the control (P< 0.01). Treatment BALB/c mice with gum obtained P. atlantica var. kurdica and Glucantime® causes decrease number of parasitologicaly positive mice (P< 0.05). Conclusion Our results show that gum obtained P. atlantica var. kurdica can be used for controlling cutaneous leishmaniasis caused by L. major and inhibiting development of cutaneous leishmaniasis lesions. PMID:23112988

  2. An acoustic experimental and theoretical investigation of single disc propellers

    NASA Technical Reports Server (NTRS)

    Bumann, Elizabeth A.; Korkan, Kenneth D.

    1989-01-01

    An experimental study of the acoustic field associated with two, three, and four blade propeller configurations with a blade root angle of 50 deg was performed in the Texas A&M University 5 ft. x 6 ft. acoustically-insulated subsonic wind tunnel. A waveform analysis package was utilized to obtain experimental acoustic time histories, frequency spectra, and overall sound pressure level (OASPL) and served as a basis for comparison to the theoretical acoustic compact source theory of Succi (1979). Valid for subsonic tip speeds, the acoustic analysis replaced each blade by an array of spiraling point sources which exhibited a unique force vector and volume. The computer analysis of Succi was modified to include a propeller performance strip analysis which used a NACA 4-digit series airfoil data bank to calculate lift and drag for each blade segment given the geometry and motion of the propeller. Theoretical OASPL predictions were found to moderately overpredict experimental values for all operating conditions and propeller configurations studied.

  3. EPR investigation of gamma irradiated single crystal guaifenesin: A combined experimental and computational study

    NASA Astrophysics Data System (ADS)

    Tasdemir, Halil Ugur; Sayin, Ulku; Türkkan, Ercan; Ozmen, Ayhan

    2016-04-01

    Gamma irradiated single crystal of Guaifenesin (Glyceryl Guaiacolate), an important expectorant drug, were investigated with Electron Paramagnetic Resonance (EPR) spectroscopy between 123 and 333 K temperature at different orientations in the magnetic field. Considering the chemical structure and the experimental spectra of the gamma irradiated single crystal of guaifenesin sample, we assumed that alkoxy or alkyl-type paramagnetic species may be produced by irradiation. Depending on this assumption, eight possible alkoxy and alkyl-type radicals were modeled and EPR parameters of these modeled radicals were calculated using the B3LYP/6-311++G(d,p)-level of density functional theory (DFT). Theoretically calculated values of alkyl-type modeled radical(R3) are in good agreement with experimentally determined EPR parameters of single crystal. Furthermore, simulation spectra which are obtained by using the theoretical initial values are well matched with the experimental spectra. It was determined that a stable Cα •H2αCβHβCγH2γ (R3) alkyl radical was produced in the host crystal as a result of gamma irradiation.

  4. Kinetic parameters of the GUINEVERE reference configuration in VENUS-F reactor obtained from a pile noise experiment using Rossi and Feynman methods

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Geslot, Benoit; Pepino, Alexandra; Blaise, Patrick

    A pile noise measurement campaign has been conducted by the CEA in the VENUS-F reactor (SCK-CEN, Mol Belgium) in April 2011 in the reference critical configuration of the GUINEVERE experimental program. The experimental setup made it possible to estimate the core kinetic parameters: the prompt neutron decay constant, the delayed neutron fraction and the generation time. A precise assessment of these constants is of prime importance. In particular, the effective delayed neutron fraction is used to normalize and compare calculated reactivities of different subcritical configurations, obtained by modifying either the core layout or the control rods position, with experimental onesmore » deduced from the analysis of measurements. This paper presents results obtained with a CEA-developed time stamping acquisition system. Data were analyzed using Rossi-α and Feynman-α methods. Results were normalized to reactor power using a calibrated fission chamber with a deposit of Np-237. Calculated factors were necessary to the analysis: the Diven factor was computed by the ENEA (Italy) and the power calibration factor by the CNRS/IN2P3/LPC Caen. Results deduced with both methods are consistent with respect to calculated quantities. Recommended values are given by the Rossi-α estimator, that was found to be the most robust. The neutron generation time was found equal to 0.438 ± 0.009 μs and the effective delayed neutron fraction is 765 ± 8 pcm. Discrepancies with the calculated value (722 pcm, calculation from ENEA) are satisfactory: -5.6% for the Rossi-α estimate and -2.7% for the Feynman-α estimate. (authors)« less

  5. Replica and extreme-value analysis of the Jarzynski free-energy estimator

    NASA Astrophysics Data System (ADS)

    Palassini, Matteo; Ritort, Felix

    2008-03-01

    We analyze the Jarzynski estimator of free-energy differences from nonequilibrium work measurements. By a simple mapping onto Derrida's Random Energy Model, we obtain a scaling limit for the expectation of the bias of the estimator. We then derive analytical approximations in three different regimes of the scaling parameter x = log(N)/W, where N is the number of measurements and W the mean dissipated work. Our approach is valid for a generic distribution of the dissipated work, and is based on a replica symmetry breaking scheme for x >> 1, the asymptotic theory of extreme value statistics for x << 1, and a direct approach for x near one. The combination of the three analytic approximations describes well Monte Carlo data for the expectation value of the estimator, for a wide range of values of N, from N=1 to large N, and for different work distributions. Based on these results, we introduce improved free-energy estimators and discuss the application to the analysis of experimental data.

  6. Characterization of rhenium compounds obtained by electrochemical synthesis after aging process

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vargas-Uscategui, Alejandro, E-mail: avargasuscat@ing.uchile.cl; Mosquera, Edgar; López-Encarnación, Juan M.

    2014-12-15

    The proper identification of the molecular nature of the aged rhenium compound obtained by means of electrodeposition from an alkaline aqueous electrolyte was determined. Chemical, structural and vibrational experimental characterization of the aged Re compound showed agreement with quantum-computations, thereby allowing the unambiguous identification of the Re compound as H(ReO{sub 4})H{sub 2}O. - Graphical abstract: Rhenium oxides were electrodeposited on a copper surface and after environmental aging was formed the H(ReO{sub 4})H{sub 2}O compound. The characterization of the synthesized material was made through the comparison of experimental evidence with quantum mechanical computations carried out by means of density functional theorymore » (DFT). - Highlights: • Aged rhenium compound obtained by means of electrodeposition was studied. • The study was made by combining experimental and DFT-computational information. • The aged electrodeposited material is consistent with the H(ReO{sub 4})H{sub 2}O compound.« less

  7. Determination of calibration constants for the hole-drilling residual stress measurement technique applied to orthotropic composites. II - Experimental evaluations

    NASA Technical Reports Server (NTRS)

    Prasad, C. B.; Prabhakaran, R.; Tompkins, S.

    1987-01-01

    The first step in the extension of the semidestructive hole-drilling technique for residual stress measurement to orthotropic composite materials is the determination of the three calibration constants. Attention is presently given to an experimental determination of these calibration constants for a highly orthotropic, unidirectionally-reinforced graphite fiber-reinforced polyimide composite. A comparison of the measured values with theoretically obtained ones shows agreement to be good, in view of the many possible sources of experimental variation.

  8. 7 CFR 765.353 - Determining market value.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Determining market value. 765.353 Section 765.353... Determining market value. (a) Security proposed for disposition. (1) The Agency will obtain an appraisal of... estimated value is less than $25,000. (b) Security remaining after disposition. The Agency will obtain an...

  9. Semi-experimental equilibrium structure of pyrazinamide from gas-phase electron diffraction. How much experimental is it?

    NASA Astrophysics Data System (ADS)

    Tikhonov, Denis S.; Vishnevskiy, Yury V.; Rykov, Anatolii N.; Grikina, Olga E.; Khaikin, Leonid S.

    2017-03-01

    A semi-experimental equilibrium structure of free molecules of pyrazinamide has been determined for the first time using gas electron diffraction method. The refinement was carried using regularization of geometry by calculated quantum chemical parameters. It is discussed to which extent is the final structure experimental. A numerical approach for estimation of the amount of experimental information in the refined parameters is suggested. The following values of selected internuclear distances were determined (values are in Å with 1σ in the parentheses): re(Cpyrazine-Cpyrazine)av = 1.397(2), re(Npyrazine-Cpyrazine)av = 1.332(3), re(Cpyrazine-Camide) = 1.493(1), re(Namide-Camide) = 1.335(2), re(Oamide-Camide) = 1.219(1). The given standard deviations represent pure experimental uncertainties without the influence of regularization.

  10. An experimental investigation of hingeless helicopter rotor-body stability in hover

    NASA Technical Reports Server (NTRS)

    Bousman, W. G.

    1978-01-01

    Model tests of a 1.62 m diameter rotor were performed to investigate the aeromechanical stability of coupled rotor-body systems in hover. Experimental measurements were made of modal frequencies and damping over a wide range of rotor speeds. Good data were obtained for the frequencies of the rotor lead-lag regressing mode. The quality of the damping measurements of the body modes was poor due to nonlinear damping in the gimbal ball bearings. Simulated vacuum testing was performed using substitute blades of tantalum that reduced the effective lock number to 0.2% of the model scale value while keeping the blade inertia constant. The experimental data were compared with theoretical predictions, and the correlation was in general very good.

  11. Experimental Investigation of Unsteady Thrust Augmentation Using a Speaker-Driven Jet

    NASA Technical Reports Server (NTRS)

    Paxson, Daniel E.; Wernet, Mark P.; John, Wentworth T.

    2007-01-01

    An experimental investigation is described in which a simple speaker-driven jet was used as a pulsed thrust source (driver) for an ejector configuration. The objectives of the investigation were twofold. The first was to expand the experimental body of evidence showing that an unsteady thrust source, combined with a properly sized ejector generally yields higher thrust augmentation values than a similarly sized, steady driver of equivalent thrust. The second objective was to identify characteristics of the unsteady driver that may be useful for sizing ejectors, and for predicting the thrust augmentation levels that may be achieved. The speaker-driven jet provided a convenient source for the investigation because it is entirely unsteady (i.e., it has no mean velocity component) and because relevant parameters such as frequency, time-averaged thrust, and diameter are easily variable. The experimental setup will be described, as will the two main measurements techniques employed. These are thrust and digital particle imaging velocimetry of the driver. It will be shown that thrust augmentation values as high as 1.8 were obtained, that the diameter of the best ejector scaled with the dimensions of the emitted vortex, and that the so-called formation time serves as a useful dimensionless parameter by which to characterize the jet and predict performance.

  12. Experimental Evaluation of a Structure-Based Connectionist Network for Fault Diagnosis of Helicopter Gearboxes

    NASA Technical Reports Server (NTRS)

    Jammu, V. B.; Danai, K.; Lewicki, D. G.

    1998-01-01

    This paper presents the experimental evaluation of the Structure-Based Connectionist Network (SBCN) fault diagnostic system introduced in the preceding article. For this vibration data from two different helicopter gearboxes: OH-58A and S-61, are used. A salient feature of SBCN is its reliance on the knowledge of the gearbox structure and the type of features obtained from processed vibration signals as a substitute to training. To formulate this knowledge, approximate vibration transfer models are developed for the two gearboxes and utilized to derive the connection weights representing the influence of component faults on vibration features. The validity of the structural influences is evaluated by comparing them with those obtained from experimental RMS values. These influences are also evaluated ba comparing them with the weights of a connectionist network trained though supervised learning. The results indicate general agreement between the modeled and experimentally obtained influences. The vibration data from the two gearboxes are also used to evaluate the performance of SBCN in fault diagnosis. The diagnostic results indicate that the SBCN is effective in directing the presence of faults and isolating them within gearbox subsystems based on structural influences, but its performance is not as good in isolating faulty components, mainly due to lack of appropriate vibration features.

  13. Prognostic Value of Coronary Flow Reserve Obtained on Dobutamine Stress Echocardiography and its Correlation with Target Heart Rate.

    PubMed

    Abreu, José Sebastião de; Rocha, Eduardo Arrais; Machado, Isadora Sucupira; Parahyba, Isabelle O; Rocha, Thais Brito; Paes, Fernando José Villar Nogueira; Diogenes, Tereza Cristina Pinheiro; Abreu, Marília Esther Benevides de; Farias, Ana Gardenia Liberato Ponte; Carneiro, Marcia Maria; Paes, José Nogueira

    2017-05-01

    Normal coronary flow velocity reserve (CFVR) (≥ 2) obtained in the left anterior descending coronary artery (LAD) from transthoracic echocardiography is associated with a good prognosis, but there is no study correlating CFVR with submaximal target heart rate (HR). To evaluate the prognostic value of CFVR obtained in the LAD of patients with preserved (>50%) left ventricular ejection fraction (LVEF) who completed a dobutamine stress echocardiography (DSE), considering target HR. Prospective study of patients with preserved LVEF and CFVR obtained in the LAD who completed DSE. In Group I (GI = 31), normal CFVR was obtained before achieving target HR, and, in Group II (GII = 28), after that. Group III (G III=24) reached target HR, but CFVR was abnormal. Death, acute coronary insufficiency, coronary intervention, coronary angiography without further intervention, and hospitalization were considered events. In 28 ± 4 months, there were 18 (21.6%) events: 6% (2/31) in GI, 18% (5/28) in GII, and 46% (11/24) in GIII. There were 4 (4.8%) deaths, 6 (7.2%) coronary interventions and 8 (9.6%) coronary angiographies without further intervention. In event-free survival by regression analysis, GIII had more events than GI (p < 0.001) and GII (p < 0.045), with no difference between GI and GII (p = 0.160). After adjustment, the only difference was between GIII and GI (p = 0.012). In patients with preserved LVEF and who completed their DSE, normal CFVR obtained before achieving target HR was associated with better prognosis. A reserva de velocidade de fluxo coronariano (RVFC) adequada (≥ 2) obtida na artéria descendente anterior (ADA) através do ecocardiograma transtorácico associa-se a bom prognóstico, mas não há estudo correlacionando-a com a frequência cardíaca (FC) alvo (submáxima). Avaliar o valor prognóstico da RVFC obtida na ADA de pacientes com fração de ejeção do ventrículo esquerdo (FEVE) preservada (>50%) e ecocardiograma sob estresse com dobutamina

  14. Physical and optical properties of DCJTB dye for OLED display applications: Experimental and theoretical investigation

    NASA Astrophysics Data System (ADS)

    Kurban, Mustafa; Gündüz, Bayram

    2017-06-01

    In this study, 4-(dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyljulolidin-4-yl-vinyl)-4H-pyran (DCJTB) was achieved using the experimental and theoretical studies. The electronic, optical and spectroscopic properties of DCJTB molecule were first investigated by performing experimental both solution and thin film techniques and then theoretical calculations. Theoretical results showed that one intense electronic transition is 505.26 nm a quite reasonable and agreement with the measured experimental data 505.00 and 503 nm with solution technique and film technique, respectively. Experimental and simple models were also taken into consideration to calculate the optical refractive index (n) of DCJTB molecule. The structural and electronic properties were next calculated using density functional theory (DFT) with B3LYP/6-311G (d, p) basis set. UV, FT-IR spectra characteristics and the electronic properties, such as frontier orbitals, and band gap energy (Eg) of DCJTB were also recorded time-dependent (TD) DFT approach. The theoretical Eg value were found to be 2.269 eV which is consistent with experimental results obtained from solution technique for THF solvent (2.155 eV) and literature (2.16 eV). The results herein obtained reveal that solution is simple, cost-efficient and safe for optoelectronic applications when compared with film technique.

  15. Health values and prospect theory.

    PubMed

    Treadwell, J R; Lenert, L A

    1999-01-01

    Health values are important components of medical decisions. Experimental data suggest that people value health in complex and dynamic ways. Prospect theory is a descriptive theory of choice that may accurately characterize how people assign values to health states. The authors first provide background on prospect theory and how it can be applied to health values. Next, they review the relevant health research and find mixed support for prospect theory. Last, they discuss implications of prospect theory for cost-effectiveness analysis. The application of prospect theory to health deserves further research because it may help clarify the link between health and values.

  16. Acid-base properties of the N3 ruthenium(II) solar cell sensitizer: a combined experimental and computational analysis.

    PubMed

    Pizzoli, Giuliano; Lobello, Maria Grazia; Carlotti, Benedetta; Elisei, Fausto; Nazeeruddin, Mohammad K; Vitillaro, Giuseppe; De Angelis, Filippo

    2012-10-14

    We report a combined spectro-photometric and computational investigation of the acid-base equilibria of the N3 solar cell sensitizer [Ru(dcbpyH(2))(2)(NCS)(2)] (dcbpyH(2) = 4,4'-dicarboxyl-2,2' bipyridine) in aqueous/ethanol solutions. The absorption spectra of N3 recorded at various pH values were analyzed by Single Value Decomposition techniques, followed by Global Fitting procedures, allowing us to identify four separate acid-base equilibria and their corresponding ground state pK(a) values. DFT/TDDFT calculations were performed for the N3 dye in solution, investigating the possible relevant species obtained by sequential deprotonation of the four dye carboxylic groups. TDDFT excited state calculations provided UV-vis absorption spectra which nicely agree with the experimental spectral shapes at various pH values. The calculated pK(a) values are also in good agreement with experimental data, within <1 pK(a) unit. Based on the calculated energy differences a tentative assignment of the N3 deprotonation pathway is reported.

  17. Experimental and theoretical studies on vibrational spectra of 4-(2-furanylmethyleneamino)antipyrine, 4-benzylideneaminoantipyrine and 4-cinnamilideneaminoantipyrine

    NASA Astrophysics Data System (ADS)

    Sun, Yu-Xi; Hao, Qing-Li; Yu, Zong-Xue; Jiang, Wen-Jun; Lu, Lu-De; Wang, Xin

    2009-09-01

    This work deals with the IR and Raman spectroscopy of 4-(2-furanylmethyleneamino) antipyrine (FAP), 4-benzylideneaminoantipyrine (BAP) and 4-cinnamilideneaminoantipyrine (CAP) by means of experimental and quantum chemical calculations. The equilibrium geometries, harmonic frequencies, infrared intensities and Raman scattering activities were calculated by density functional B3LYP method with the 6-31G(d) basis set. The comparisons between the calculated and experimental results covering molecular structures, assignments of fundamental vibrational modes and thermodynamic properties were investigated. The optimized molecular geometries have been compared with the experimental data obtained from XRD data, which indicates that the theoretical results agree well with the corresponding experimental values. For the three compounds, comparisons and assignments of the vibrational frequencies indicate that the calculated frequencies are close to the experimental data, and the IR spectra are comparable with some slight differences, whereas the Raman spectra are different clearly and the strongest Raman scattering actives are relative tightly to the molecular conjugative moieties linked through their Schiff base imines. The thermodynamic properties (heat capacities, entropies and enthalpy changes) and their correlations with temperatures were also obtained from the harmonic frequencies of the optimized strucutres.

  18. Determination of pKa values of new phenacyl-piperidine derivatives by potentiometric titration method in aqueous medium at room temperature (25±0.5oC).

    PubMed

    Zafar, Shaista; Akhtar, Shamim; Tariq, Talat; Mushtaq, Noushin; Akram, Arfa; Ahmed, Ahsaan; Arif, Muhammad; Naeem, Sabahat; Anwar, Sana

    2014-07-01

    Dissociation constant (pKa) of ten novel phenacyl derivatives of piperidine were determined by potentiometric titration method in aqueous medium at room temperature (25 ±0.5°C). The sample solutions were prepared in deionized water with ionic strength 0.01M and titrated with 0.1M NaOH solution. In addition, ΔG values were also calculated. Different prediction software programs were used to calculate pKa values too and compared to the experimentally observed pKa values. The experimental and theoretical values were found in close agreement. The results obtained in this research would help to predict the good absorption of the studied compounds and can be selected as lead molecules for the synthesis of CNS active agents because of their lipophilic nature especially compound VII.

  19. Effects of different crystal faces on the surface charge of colloidal goethite (α-FeOOH) particles: an experimental and modeling study

    NASA Astrophysics Data System (ADS)

    Gaboriaud, Fabien; Ehrhardt, Jean-Jacques

    2003-03-01

    The surface charge of colloidal particles is usually determined by potentiometric titration. These acid-base titrations make it possible to measure the pH of point-of-zero charge (pzc) for oxide minerals. This macroscopic property is the most important parameter used in surface complexation modeling to reproduce experimental data. The pzc values of goethite reported in the literature vary between 7.0 and 9.5. Carbonate adsorption and/or surface morphology are thought to account for this wide range. We demonstrate a procedure for the removal of the carbonate ions that initially adsorb on goethite and strongly affect the titration curves and pzc determination. We also investigated the crystal-face-specific reactivity of two morphologically different goethites. The z-profiles obtained from atomic force microscopy (AFM) images showed that the goethite with the smallest specific surface area ( S = 49 m 2/g, denoted G49) exhibits 70% of the (001) face, whereas this value is only 30% for the goethite with largest specific surface area ( S = 95 m 2/g, denoted G95). This morphologic difference results in slightly different pzc values: 9.0 for G49 goethite and 9.1 for G95 geothite. These experimental pzc values have been correlated with multisite complexation calculations using both the full-site and the 1-pK approaches. We used the full-site approach to consider all of the configurations of hydrogen bond interactions with surface site. The resulting mean charges gave estimated pzc values of 8.9 and 9.2 for the (001) and (101) faces, respectively. Considering these theoretical pzc values for individual faces and the face distributions obtained from AFM analysis, the calculated pzc values are in full agreement with the experimental pzc values. However, this morphologic difference is more expressed in surface charge values than in the pzc values. Indeed, the surface charge of G49 goethite is much higher than that of G95 goethite, and the 1-pK calculations make it possible to

  20. [The determination of the discrepancy between the mathematically ascertained and experimentally provable efficiency of UV facilities for water disinfection].

    PubMed

    Leuker, G; Hingst, V

    1992-10-01

    Using three UV-plants of different technical designs for water disinfection, we studied the conformity between experimental germ reduction using standard test organisms and calculated UV-doses under various water flow conditions. Taking into consideration the style of construction of the UV-plants, the irradiation area and the layer thickness were used as constant parameters for dose calculations. This was also employed for the irradiation intensity, since the experiments were performed for a relatively short period compared of the life span of the UV-irradiators. Both exposure time and water transmission were employed as variable parameters in the dose calculations and experimental procedures respectively. The calculated UV-dose and experimentally obtained germ reduction values were comparatively the same for two of the three UV-plants studied. However, no correlation was observed between the reduction of E. coli and the corresponding calculated UV-dose values. Therefore, the calculated UV-dose values for any given UV-plant should be considered to be relative and by no means absolute values. We are of the opinion that within a certain range of water flow rate and transmission, antimicrobial effectiveness of different UV-plants should be demonstrated independent of dose values, technical and other construction characteristics. The applicability of the UV-plants studied is discussed.

  1. Spin-up flow of ferrofluids: Asymptotic theory and experimental measurements

    NASA Astrophysics Data System (ADS)

    Chaves, Arlex; Zahn, Markus; Rinaldi, Carlos

    2008-05-01

    We treat the flow of ferrofluid in a cylindrical container subjected to a uniform rotating magnetic field, commonly referred to as spin-up flow. A review of theoretical and experimental results published since the phenomenon was first observed in 1967 shows that the experimental data from surface observations of tracer particles are inadequate for the assessment of bulk flow theories. We present direct measurements of the bulk flow by using the ultrasound velocity profile method, and torque measurements for water and kerosene based ferrofluids, showing the fluid corotating with the field in a rigid-body-like fashion throughout most of the bulk region of the container, except near the air-fluid interface, where it was observed to counter-rotate. We obtain an extension of the spin diffusion theory of Zaitsev and Shliomis, using the regular perturbation method. The solution is rigorously valid for αK≪√3/2 , where αK is the Langevin parameter evaluated by using the applied field magnitude, and provides a means for obtaining successively higher contributions of the nonlinearity of the equilibrium magnetization response and the spin-magnetization coupling in the magnetization relaxation equation. Because of limitations in the sensitivity of our apparatus, experiments were carried out under conditions for which α ˜1. Still, under such conditions the predictions of the analysis are in good qualitative agreement with the experimental observations. An estimate of the spin viscosity is obtained from comparison of flow measurements and theoretical results of the extrapolated wall velocity from the regular perturbation method. The estimated value lies in the range of 10-8-10-12kgms-1 and is several orders of magnitude higher than that obtained from dimensional analysis of a suspension of noninteracting particles in a Newtonian fluid.

  2. Refined method for predicting electrochemical windows of ionic liquids and experimental validation studies.

    PubMed

    Zhang, Yong; Shi, Chaojun; Brennecke, Joan F; Maginn, Edward J

    2014-06-12

    A combined classical molecular dynamics (MD) and ab initio MD (AIMD) method was developed for the calculation of electrochemical windows (ECWs) of ionic liquids. In the method, the liquid phase of ionic liquid is explicitly sampled using classical MD. The electrochemical window, estimated by the energy difference between the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO), is calculated at the density functional theory (DFT) level based on snapshots obtained from classical MD trajectories. The snapshots were relaxed using AIMD and quenched to their local energy minima, which assures that the HOMO/LUMO calculations are based on stable configurations on the same potential energy surface. The new procedure was applied to a group of ionic liquids for which the ECWs were also experimentally measured in a self-consistent manner. It was found that the predicted ECWs not only agree with the experimental trend very well but also the values are quantitatively accurate. The proposed method provides an efficient way to compare ECWs of ionic liquids in the same context, which has been difficult in experiments or simulation due to the fact that ECW values sensitively depend on experimental setup and conditions.

  3. Social Value Induction and Cooperation in the Centipede Game

    PubMed Central

    2016-01-01

    The Centipede game provides a dynamic model of cooperation and competition in repeated dyadic interactions. Two experiments investigated psychological factors driving cooperation in 20 rounds of a Centipede game with significant monetary incentives and anonymous and random re-pairing of players after every round. The main purpose of the research was to determine whether the pattern of strategic choices observed when no specific social value orientation is experimentally induced—the standard condition in all previous investigations of behavior in the Centipede and most other experimental games—is essentially individualistic, the orthodox game-theoretic assumption being that players are individualistically motivated in the absence of any specific motivational induction. Participants in whom no specific state social value orientation was induced exhibited moderately non-cooperative play that differed significantly from the pattern found when an individualistic orientation was induced. In both experiments, the neutral treatment condition, in which no orientation was induced, elicited competitive behavior resembling behavior in the condition in which a competitive orientation was explicitly induced. Trait social value orientation, measured with a questionnaire, influenced cooperation differently depending on the experimentally induced state social value orientation. Cooperative trait social value orientation was a significant predictor of cooperation and, to a lesser degree, experimentally induced competitive orientation was a significant predictor of non-cooperation. The experimental results imply that the standard assumption of individualistic motivation in experimental games may not be valid, and that the results of such investigations need to take into account the possibility that players are competitively motivated. PMID:27010385

  4. Experimental and Theoretical Studies on the Viscosity-Structure Correlation for High Alumina-Silicate Melts

    NASA Astrophysics Data System (ADS)

    Talapaneni, Trinath; Yedla, Natraj; Pal, Snehanshu; Sarkar, Smarajit

    2017-06-01

    Blast furnaces are encountering high Alumina (Al2O3 > 25 pct) in the final slag due to the charging of low-grade ores. To study the viscosity behavior of such high alumina slags, synthetic slags are prepared in the laboratory scale by maintaining a chemical composition of Al2O3 (25 to 30 wt pct) CaO/SiO2 ratio (0.8 to 1.6) and MgO (8 to 16 wt pct). A chemical thermodynamic software FactSage 7.0 is used to predict liquidus temperature and viscosity of the above slags. Experimental viscosity measurements are performed above the liquidus temperature in the range of 1748 K to 1848 K (1475 °C to 1575 °C). The viscosity values obtained from FactSage closely fit with the experimental values. The viscosity and the slag structure properties are intent by Fourier Transform Infrared (FTIR) and Raman spectroscopy. It is observed that increase in CaO/SiO2 ratio and MgO content in the slag depolymerizes the silicate structure. This leads to decrease in viscosity and activation energy (167 to 149 kJ/mol) of the slag. Also, an addition of Al2O3 content increases the viscosity of slag by polymerization of alumino-silicate structure and activation energy from 154 to 161 kJ/mol. It is witnessed that the activation energy values obtained from experiment closely fit with the Shankar model based on Arrhenius equation.

  5. Are There Scenarios When the Use of Non-Placebo-Control Groups in Experimental Trial Designs Increase Expected Value to Society?

    PubMed

    Uyei, Jennifer; Braithwaite, R Scott

    2016-01-01

    Despite the benefits of the placebo-controlled trial design, it is limited by its inability to quantify total benefits and harms. Such trials, for example, are not designed to detect an intervention's placebo or nocebo effects, which if detected could alter the benefit-to-harm balance and change a decision to adopt or reject an intervention. In this article, we explore scenarios in which alternative experimental trial designs, which differ in the type of control used, influence expected value across a range of pretest assumptions and study sample sizes. We developed a decision model to compare 3 trial designs and their implications for decision making: 2-arm placebo-controlled trial ("placebo-control"), 2-arm intervention v. do nothing trial ("null-control"), and an innovative 3-arm trial design: intervention v. do nothing v. placebo trial ("novel design"). Four scenarios were explored regarding particular attributes of a hypothetical intervention: 1) all benefits and no harm, 2) no biological effect, 3) only biological effects, and 4) surreptitious harm (no biological benefit or nocebo effect). Scenario 1: When sample sizes were very small, the null-control was preferred, but as sample sizes increased, expected value of all 3 designs converged. Scenario 2: The null-control was preferred regardless of sample size when the ratio of placebo to nocebo effect was >1; otherwise, the placebo-control was preferred. Scenario 3: When sample size was very small, the placebo-control was preferred when benefits outweighed harms, but the novel design was preferred when harms outweighed benefits. Scenario 4: The placebo-control was preferred when harms outweighed placebo benefits; otherwise, preference went to the null-control. Scenarios are hypothetical, study designs have not been tested in a real-world setting, blinding is not possible in all designs, and some may argue the novel design poses ethical concerns. We identified scenarios in which alternative experimental study

  6. Experimental characterization of Fresnel-Köhler concentrators

    NASA Astrophysics Data System (ADS)

    Zamora, Pablo; Benítez, Pablo; Mohedano, Rubén; Cvetković, Aleksandra; Vilaplana, Juan; Li, Yang; Hernández, Maikel; Chaves, Julio; Miñano, Juan C.

    2012-01-01

    Most cost-effective concentrated photovoltaics (CPV) systems are based on an optical train comprising two stages, the first being a Fresnel lens. Among them, the Fresnel-Köhler (FK) concentrator stands out owing to both performance and practical reasons. We describe the experimental measurements procedure for FK concentrator modules. This procedure includes three main types of measurements: electrical efficiency, acceptance angle, and irradiance uniformity at the solar cell plane. We have collected here the performance features of two different FK prototypes (ranging different f-numbers, concentration ratios, and cell sizes). The electrical efficiencies measured in both prototypes are high and fit well with the models, achieving values up to 32.7% (temperature corrected, and with no antireflective coating on SOE or POE surfaces) in the best case. The measured angular transmission curves show large acceptance angles, again perfectly matching the expected values [measured concentration acceptance product (CAP) values over 0.56]. The irradiance pattern on the cell (obtained with a digital camera) shows an almost perfectly uniform distribution, as predicted by raytrace simulations. All these excellent on-sun results confirm the FK concentrator as a potentially cost-effective solution for the CPV market.

  7. 14 CFR 21.275 - Experimental certificates.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Experimental certificates. 21.275 Section... CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS Delegation Option Authorization Procedures § 21.275 Experimental certificates. (a) The manufacturer shall, before issuing an experimental certificate, obtain from the...

  8. 14 CFR 21.275 - Experimental certificates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Experimental certificates. 21.275 Section... CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS Delegation Option Authorization Procedures § 21.275 Experimental certificates. (a) The manufacturer shall, before issuing an experimental certificate, obtain from the...

  9. Experimenter bias and subliminal perception

    ERIC Educational Resources Information Center

    Barber, Paul J.; Rushton, J. Philippe

    1975-01-01

    It has been suggested that subliminal perception phenomena may be in part due to experimenter bias effects. Two studies that obtained positive evidence of subliminal perception were therefore replicated with experimenters tested under blind and not blind conditions. (Editor)

  10. Preference-based measures to obtain health state utility values for use in economic evaluations with child-based populations: a review and UK-based focus group assessment of patient and parent choices.

    PubMed

    Wolstenholme, Jane L; Bargo, Danielle; Wang, Kay; Harnden, Anthony; Räisänen, Ulla; Abel, Lucy

    2018-03-21

    No current guidance is available in the UK on the choice of preference-based measure (PBM) that should be used in obtaining health-related quality of life from children. The aim of this study is to review the current usage of PBMs for obtaining health state utility values in child and adolescent populations, and to obtain information on patient and parent-proxy respondent preferences in completing PBMs in the UK. A literature review was conducted to determine which instrument is most frequently used for child-based economic evaluations and whether child or proxy responses are used. Instruments were compared on dimensions, severity levels, elicitation and valuation methods, availability of value sets and validation studies, and the range of utility values generated. Additionally, a series of focus groups of parents and young people (11-20 years) were convened to determine patient and proxy preferences. Five PBMs suitable for child populations were identified, although only the Health Utilities Index 2 (HUI2) and Child Heath Utility 9D (CHU-9D) have UK value sets. 45 papers used PBMs in this population, but many used non-child-specific PBMs. Most respondents were parent proxies, even in adolescent populations. Reported missing data ranged from 0.5 to 49.3%. The focus groups reported their experiences with the EQ-5D-Y and CHU-9D. Both the young persons' group and parent/proxy groups felt that the CHU-9D was more comprehensive but may be harder for a proxy to complete. Some younger children had difficulty understanding the CHU-9D questions, but the young persons' group nonetheless preferred responding directly. The use of PBMs in child populations is increasing, but many studies use PBMs that do not have appropriate value sets. Parent proxies are the most common respondents, but the focus group responses suggest it would be preferred, and may be more informative, for older children to self-report or for child-parent dyads to respond.

  11. Experimental investigation on stability and dielectric break down strength of transformer oil based nanofluids

    NASA Astrophysics Data System (ADS)

    Ravi Babu, S.; Sambasiva Rao, G.

    2018-04-01

    The main objective of this study is to investigate the stability and dielectric breakdown strength of alumina-transformer oil nanofluids as stability issue is the major concern when it is used for practical applications. UV-Vis spectrophotometer and Oil tester were used to measure absorbance and breakdown voltage of nanofluids respectively. As per the experimental results, correlations were developed using regression analysis. Experimental results were compared with the predicted values of BDVE and absorbance and presented. The maximum errors obtained by comparing the experimental and predicted results for BDVE and absorbance are -2.913% and 4.89% respectively. It is also observed that there is a decrement in both BDVE and absorbance for nanofluids of aged 1 day compared to fresh ones. This decrement is due to the sedimentation of nanoparticles.

  12. Understanding the value of plant diversity for ecosystem functioning through niche theory

    PubMed Central

    Isbell, Forest; Purves, Drew W.; Loreau, Michel

    2016-01-01

    Biodiversity experiments have generated robust empirical results supporting the hypothesis that ecosystems function better when they contain more species. Given that ecosystems provide services that are valued by humans, this inevitably suggests that the loss of species from natural ecosystems could diminish their value. This raises two important questions. First, will experimental results translate into the real world, where species are being lost at an alarming rate? And second, what are the benefits and pitfalls of such valuation exercises? We argue that the empirical results obtained in experiments are entirely consistent with well-established theories of species coexistence. We then examine the current body of work through the lens of niche theory and highlight where closer links with theory could open up opportunities for future research. We argue that niche theory predicts that diversity–functioning relationships are likely to be stronger (and require more species) in the field than in simplified experimental settings. However, we caution that while many of the biological processes that promote coexistence can also generate diversity–function relationships, there is no simple mapping between the two. This implies that valuation exercises need to proceed with care. PMID:27928043

  13. Understanding the value of plant diversity for ecosystem functioning through niche theory.

    PubMed

    Turnbull, Lindsay A; Isbell, Forest; Purves, Drew W; Loreau, Michel; Hector, Andy

    2016-12-14

    Biodiversity experiments have generated robust empirical results supporting the hypothesis that ecosystems function better when they contain more species. Given that ecosystems provide services that are valued by humans, this inevitably suggests that the loss of species from natural ecosystems could diminish their value. This raises two important questions. First, will experimental results translate into the real world, where species are being lost at an alarming rate? And second, what are the benefits and pitfalls of such valuation exercises? We argue that the empirical results obtained in experiments are entirely consistent with well-established theories of species coexistence. We then examine the current body of work through the lens of niche theory and highlight where closer links with theory could open up opportunities for future research. We argue that niche theory predicts that diversity-functioning relationships are likely to be stronger (and require more species) in the field than in simplified experimental settings. However, we caution that while many of the biological processes that promote coexistence can also generate diversity-function relationships, there is no simple mapping between the two. This implies that valuation exercises need to proceed with care. © 2016 The Author(s).

  14. Experimental Investigations of Direct and Converse Flexoelectric Effect in Bilayer Lipid Membranes.

    NASA Astrophysics Data System (ADS)

    Todorov, Angelio Todorov

    Flexoelectric coefficients (direct and converse), electric properties (capacitance and resistivity) and mechanical properties (thickness and elastic coefficients) have been determined for bilayer lipid membranes (BLMs) prepared from egg yolk lecithin (EYL), glycerol monoleate (GMO), phosphatidyl choline (PC) and phosphatidyl serine (PS) as a function of frequency, pH and surface charge modifiers. Direct flexoelectric effect manifested itself in the development of microvolt range a.c. potential (U_{f}) upon subjecting one side of a BLM to an oscillating hydrostatic pressure, in the 100-1000 Hz range. Operationally, the flexoelectric coefficient (f) is expressed by the ratio between U_{f} and the change of curvature (c) which accompanied the flexing of the membrane. Membrane curvature was determined by means of either the electric method (capacitance microphone effect) or by the newly developed method of stroboscopic interferometry. Real-time stroboscopic interferometry coupled with simultaneous electric measurements, provided a direct method for the determination of f. Two different frequency regimes of f were recognized. At low frequencies (<300 Hz), associated with free mobility of the surfactant, f-values of 24.1 times 10^{-19} and 0.87 times 10^ {-19} Coulombs were obtained for PC and GMO BLMs. At high frequencies (>300 Hz), associated with blocked mobility of the surfactant, f-values of 16.5 times 10^ {-19} and 0.30 times 10^{-19} Coulombs were obtained for PC and GMO BLMs. The theoretically calculated value for the GMO BLM oscillating at high frequency (0.12 times 10^{-19 } Coulombs) agreed well with that determined experimentally (0.3 times 10 ^{-19} Coulombs). For charged bovine brain PS BLM the observed flexocoefficient was f = 4.0 times 10^{ -18} Coulombs. Converse flexoelectric effect manifested itself in voltage-induced BLM curvature. Observations were carried out on uranyl acetate (UA) stabilized PS BLM under a.c. excitation. Frequency dependence of f

  15. A novel approach to the experimental study on methane/steam reforming kinetics using the Orthogonal Least Squares method

    NASA Astrophysics Data System (ADS)

    Sciazko, Anna; Komatsu, Yosuke; Brus, Grzegorz; Kimijima, Shinji; Szmyd, Janusz S.

    2014-09-01

    For a mathematical model based on the result of physical measurements, it becomes possible to determine their influence on the final solution and its accuracy. However, in classical approaches, the influence of different model simplifications on the reliability of the obtained results are usually not comprehensively discussed. This paper presents a novel approach to the study of methane/steam reforming kinetics based on an advanced methodology called the Orthogonal Least Squares method. The kinetics of the reforming process published earlier are divergent among themselves. To obtain the most probable values of kinetic parameters and enable direct and objective model verification, an appropriate calculation procedure needs to be proposed. The applied Generalized Least Squares (GLS) method includes all the experimental results into the mathematical model which becomes internally contradicted, as the number of equations is greater than number of unknown variables. The GLS method is adopted to select the most probable values of results and simultaneously determine the uncertainty coupled with all the variables in the system. In this paper, the evaluation of the reaction rate after the pre-determination of the reaction rate, which was made by preliminary calculation based on the obtained experimental results over a Nickel/Yttria-stabilized Zirconia catalyst, was performed.

  16. Antioxidant Capacity: Experimental Determination by EPR Spectroscopy and Mathematical Modeling.

    PubMed

    Polak, Justyna; Bartoszek, Mariola; Chorążewski, Mirosław

    2015-07-22

    A new method of determining antioxidant capacity based on a mathematical model is presented in this paper. The model was fitted to 1000 data points of electron paramagnetic resonance (EPR) spectroscopy measurements of various food product samples such as tea, wine, juice, and herbs with Trolox equivalent antioxidant capacity (TEAC) values from 20 to 2000 μmol TE/100 mL. The proposed mathematical equation allows for a determination of TEAC of food products based on a single EPR spectroscopy measurement. The model was tested on the basis of 80 EPR spectroscopy measurements of herbs, tea, coffee, and juice samples. The proposed model works for both strong and weak antioxidants (TEAC values from 21 to 2347 μmol TE/100 mL). The determination coefficient between TEAC values obtained experimentally and TEAC values calculated with proposed mathematical equation was found to be R(2) = 0.98. Therefore, the proposed new method of TEAC determination based on a mathematical model is a good alternative to the standard EPR method due to its being fast, accurate, inexpensive, and simple to perform.

  17. Characterization and comparison of perezone with some analogues. Experimental and theoretical study

    NASA Astrophysics Data System (ADS)

    Escobedo-González, Rene Gerardo; Bahena, Luis; Arias Tellez, José Luis; Hinojosa Torres, Jaime; Ruvalcaba, Rene Miranda; Aceves-Hernández, Juan Manuel

    2015-10-01

    Perezone had been used for centuries in the traditional Mexican medicine, it is useful and a handful of illness. Perezone and other derivatives also present activity against certain lines of cancer, such as the myeloblastoid leukemia cell line K-562 and carcinoma cell lines (PC-3 and SKLU-1) with IC50 <10 μM. Perezone and isoperezone have shown the major cytotoxic potency. Characterization of perezone was carried out by UV-Visible, IR, DSC, TGA and powder X-ray diffraction, as well as docking studies using caspase-3 structures as receptors. Theoretical studies for optimizing the geometry of perezone were carried out and the results compared with values of single crystal X-ray diffraction. The experimental values of atomic distances, angles and dihedral angles are in good agreement with the theoretical values. Interaction of perezone with the cysteine catalytic site with the caspase-3 was found in the docking studies. A docking study of perezone, with horminone, thymoquinone and isoperezone as ligands and the protein apoptein, caspase-3 as receptor, was carried to demonstrate that the hindrance steric factor, chemical structure and the functional groups are important in the biological activity of these natural products. The docking score energetic values are in good agreement with the experimental cytotoxic results obtained from the experiments when perezone and analogues were studied in different types of cancer.

  18. Meaning That Social Studies Teacher Candidates Give to Value Concept and Their Value Rankings

    ERIC Educational Resources Information Center

    Aysegül, Tural

    2018-01-01

    This work determines the role that value education plays in shaping people's personal and social life. This research aims to put forward meaning that social studies teacher candidates give to value concept and its value ranking. To achieve this aim, the opinions of 12 social studies teacher candidates were obtained. During the data collection…

  19. Thermal mirror spectrometry: An experimental investigation of optical glasses

    NASA Astrophysics Data System (ADS)

    Zanuto, V. S.; Herculano, L. S.; Baesso, M. L.; Lukasievicz, G. V. B.; Jacinto, C.; Malacarne, L. C.; Astrath, N. G. C.

    2013-03-01

    The Thermal mirror technique relies on measuring laser-induced nanoscale surface deformation of a solid sample. The amplitude of the effect is directly dependent on the optical absorption and linear thermal expansion coefficients, and the time evolution depends on the heat diffusion properties of the sample. Measurement of transient signals provide direct access to thermal, optical and mechanical properties of the material. The theoretical models describing this effect can be formulated for very low optical absorbing and for absorbing materials. In addition, the theories describing the effect apply for semi-infinite and finite samples. In this work, we apply the Thermal mirror technique to measure physical properties of optical glasses. The semi-infinite and finite models are used to investigate very low optical absorbing glasses. The thickness limit for which the semi-infinite model retrieves the correct values of the thermal diffusivity and amplitude of the transient is obtained using the finite description. This procedure is also employed on absorbing glasses, and the semi-infinite Beer-Lambert law model is used to analyze the experimental data. The experimental data show the need to use the finite model for samples with very low bulk absorption coefficients and thicknesses L < 1.5 mm. This analysis helped to establish limit values of thickness for which the semi-infinite model for absorbing materials could be used, L > 1.0 mm in this case. In addition, the physical properties of the samples were calculated and absolute values derived.

  20. Linear free-energy relationships between a single gas-phase ab initio equilibrium bond length and experimental pKa values in aqueous solution.

    PubMed

    Alkorta, Ibon; Popelier, Paul L A

    2015-02-02

    Remarkably simple yet effective linear free energy relationships were discovered between a single ab initio computed bond length in the gas phase and experimental pKa values in aqueous solution. The formation of these relationships is driven by chemical features such as functional groups, meta/para substitution and tautomerism. The high structural content of the ab initio bond length makes a given data set essentially divide itself into high correlation subsets (HCSs). Surprisingly, all molecules in a given high correlation subset share the same conformation in the gas phase. Here we show that accurate pKa values can be predicted from such HCSs. This is achieved within an accuracy of 0.2 pKa units for 5 drug molecules. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Experimental investigation of hypersonic aerodynamics

    NASA Technical Reports Server (NTRS)

    Intrieri, Peter F.

    1988-01-01

    An extensive series of ballistic range tests were conducted at the Ames Research Center to determine precisely the aerodynamic characteristics of the Galileo entry probe vehicle. Figures and tables are presented which summarize the results of these ballistic range tests. Drag data were obtained for both a nonablated and a hypothesized ablated Galileo configuration at Mach numbers from about 0.7 to 14 and at Reynolds numbers from 1000 to 4 million. The tests were conducted in air and the experimental results were compared with available Pioneer Venus data since these two configurations are similar in geometry. The nonablated Galileo configuration was also tested with two different center-of-gravity positions to obtain values of pitching-moment-curve slope which could be used in determining values of lift and center-of-pressure location for this configuration. The results indicate that the drag characteristics of the Galileo probe are qualitatively similar to that of Pioneer Venus, however, the drag of the nonablated Galileo is about 3 percent lower at the higher Mach numbers and as much as 5 percent greater at transonic Mach numbers of about 1.0 to 1.5. Also, the drag of the hypothesized ablated configuration is about 3 percent lower than that of the nonablated configuration at the higher Mach numbers but about the same at the lower Mach numbers. Additional tests are required at Reynolds numbers of 1000, 500, and 250 to determine if the dramatic rise in drag coefficient measured for Pioneer Venus at these low Reynolds numbers also occurs for Galileo, as might be expected.

  2. Mechanical Degradation of Graphite/PVDF Composite Electrodes: A Model-Experimental Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Takahashi, Kenji; Higa, Kenneth; Mair, Sunil

    2015-12-11

    Mechanical failure modes of a graphite/polyvinylidene difluoride (PVDF) composite electrode for lithium-ion batteries were investigated by combining realistic stress-stain tests and mathematical model predictions. Samples of PVDF mixed with conductive additive were prepared in a similar way to graphite electrodes and tested while submerged in electrolyte solution. Young's modulus and tensile strength values of wet samples were found to be approximately one-fifth and one-half of those measured for dry samples. Simulations of graphite particles surrounded by binder layers given the measured material property values suggest that the particles are unlikely to experience mechanical damage during cycling, but that the fatemore » of the surrounding composite of PVDF and conductive additive depends completely upon the conditions under which its mechanical properties were obtained. Simulations using realistic property values produced results that were consistent with earlier experimental observations.« less

  3. Simulation and experimental study of rheological properties of CeO2-water nanofluid

    NASA Astrophysics Data System (ADS)

    Loya, Adil; Stair, Jacqueline L.; Ren, Guogang

    2015-10-01

    Metal oxide nanoparticles offer great merits over controlling rheological, thermal, chemical and physical properties of solutions. The effectiveness of a nanoparticle to modify the properties of a fluid depends on its diffusive properties with respect to the fluid. In this study, rheological properties of aqueous fluids (i.e. water) were enhanced with the addition of CeO2 nanoparticles. This study was characterized by the outcomes of simulation and experimental results of nanofluids. The movement of nanoparticles in the fluidic media was simulated by a large-scale molecular thermal dynamic program (i.e. LAMMPS). The COMPASS force field was employed with smoothed particle hydrodynamic potential (SPH) and discrete particle dynamics potential (DPD). However, this study develops the understanding of how the rheological properties are affected due to the addition of nanoparticles in a fluid and the way DPD and SPH can be used for accurately estimating the rheological properties with Brownian effect. The rheological results of the simulation were confirmed by the convergence of the stress autocorrelation function, whereas experimental properties were measured using a rheometer. These rheological values of simulation were obtained and agreed within 5 % of the experimental values; they were identified and treated with a number of iterations and experimental tests. The results of the experiment and simulation show that 10 % CeO2 nanoparticles dispersion in water has a viscosity of 2.0-3.3 mPas.

  4. An experimental and modeling study of humic acid concentration effect on H(+) binding: Application of the NICA-Donnan model.

    PubMed

    Vidali, Roza; Remoundaki, Emmanouela; Tsezos, Marios

    2009-11-15

    Humic substances are the most abundant components of the colloidal and the dissolved fraction of natural organic matter (NOM) and they are characterized by a strong binding capacity for both metals and organic pollutants, affecting their mobility and bioavailability. The understanding of the humic acidic character is the first necessary step for the study of the mechanisms of binding of other positively charged soluble metal species by humic molecules. The present work, which constitutes part of the Ph.D. thesis of Roza Vidali, reports results on the influence of the concentration of humic acids on the binding of protons obtained through both an experimental and a modeling approach. A reference purified peat humic acid (PPHA) isolated by the International Humic Substances Society (IHSS) and a humic acid from a Greek soil (GHA) were experimentally studied at various humic acid concentrations, ranging from 20 to 200mgL(-1). The proton binding isotherms obtained at different humic acid concentrations have shown that proton binding is dependent on the concentration of both humic acids. Proton binding experimental data were fitted to the NICA-Donnan model and the model parameter values were calculated for humic acid concentrations of 20 and >or=100mgL(-1). The results obtained for the NICA-Donnan parameters at humic acid concentrations >or=100mgL(-1) are in excellent agreement with those reported in the literature. However, these model parameter values cannot be used for modeling and predicting cation binding in natural aquatic systems, where humic acid concentrations are much lower. Two sets of the NICA-Donnan parameters are reported: one for humic acid concentrations of >or=100mgL(-1) and one for humic acid concentration of 20mgL(-1). The significance of the parameters values for each concentration level is also discussed.

  5. The Intramolecular Hydrogen Bond N-H···S in 2,2'-Diaminodiphenyl Disulfide: Experimental and Computational Thermochemistry.

    PubMed

    Ramos, Fernando; Flores, Henoc; Hernández-Pérez, Julio M; Sandoval-Lira, Jacinto; Camarillo, E Adriana

    2018-01-11

    The intramolecular hydrogen bond of the N-H···S type has been investigated sparingly by thermochemical and computational methods. In order to study this interaction, the standard molar enthalpies of formation in gaseous phase of diphenyl disulfide, 2,2'-diaminodiphenyl disulfide and 4,4'-diaminodiphenyl disulfide at T = 298.15 K were determined by experimental thermochemical methods and computational calculations. The experimental enthalpies of formation in gas-phase were obtained from enthalpies of formation in crystalline phase and enthalpies of sublimation. Enthalpies of formation in crystalline phase were obtained using rotatory bomb combustion calorimetry. By thermogravimetry, enthalpies of vaporization were obtained, and by combining them with enthalpies of fusion, the enthalpies of sublimation were calculated. The Gaussian-4 procedure and the atomization method were applied to obtain enthalpies of formation in gas-phase of the compounds under study. Theoretical and experimental values are in good agreement. Through natural bond orbital (NBO) analysis and a topological analysis of the electronic density, the intramolecular hydrogen bridge (N-H···S) in the 2,2'-diaminodiphenyl disulfide was confirmed. Finally, an enthalpic difference of 11.8 kJ·mol -1 between the 2,2'-diaminodiphenyl disulfide and 4,4'-diaminodiphenyl disulfide was found, which is attributed to the intramolecular N-H···S interaction.

  6. Influence of fuel moisture content and reactor temperature on the calorific value of syngas resulted from gasification of oil palm fronds.

    PubMed

    Atnaw, Samson Mekbib; Sulaiman, Shaharin Anwar; Yusup, Suzana

    2014-01-01

    Biomass wastes produced from oil palm mills and plantations include empty fruit bunches (EFBs), shells, fibers, trunks, and oil palm fronds (OPF). EFBs and shells are partially utilized as boiler fuel while the rest of the biomass materials like OPF have not been utilized for energy generation. No previous study has been reported on gasification of oil palm fronds (OPF) biomass for the production of fuel gas. In this paper, the effect of moisture content of fuel and reactor temperature on downdraft gasification of OPF was experimentally investigated using a lab scale gasifier of capacity 50 kW. In addition, results obtained from equilibrium model of gasification that was developed for facilitating the prediction of syngas composition are compared with experimental data. Comparison of simulation results for predicting calorific value of syngas with the experimental results showed a satisfactory agreement with a mean error of 0.1 MJ/Nm³. For a biomass moisture content of 29%, the resulting calorific value for the syngas was found to be only 2.63 MJ/Nm³, as compared to nearly double (4.95 MJ/Nm³) for biomass moisture content of 22%. A calorific value as high as 5.57 MJ/Nm³ was recorded for higher oxidation zone temperature values.

  7. Glass transition temperatures of liquid prepolymers obtained by thermal penetrometry

    NASA Technical Reports Server (NTRS)

    Potts, J. E., Jr.; Ashcraft, A. C.

    1973-01-01

    Thermal penetrometry is experimental technique for detecting temperature at which frozen prepolymer becomes soft enough to be pierced by weighted penetrometer needle; temperature at which this occurs is called penetration temperature. Apparatus used to obtain penetration temperatures can be set up largely from standard parts.

  8. The problem with value

    PubMed Central

    O’Doherty, John P.

    2015-01-01

    Neural correlates of value have been extensively reported in a diverse set of brain regions. However, in many cases it is difficult to determine whether a particular neural response pattern corresponds to a value-signal per se as opposed to an array of alternative non-value related processes, such as outcome-identity coding, informational coding, encoding of autonomic and skeletomotor consequences, alongside previously described “salience” or “attentional” effects. Here, I review a number of experimental manipulations that can be used to test for value, and I identify the challenges in ascertaining whether a particular neural response is or is not a value signal. Finally, I emphasize that some non-value related signals may be especially informative as a means of providing insight into the nature of the decision-making related computations that are being implemented in a particular brain region. PMID:24726573

  9. Experimental Protocol to Determine the Chloride Threshold Value for Corrosion in Samples Taken from Reinforced Concrete Structures

    PubMed Central

    Angst, Ueli M.; Boschmann, Carolina; Wagner, Matthias; Elsener, Bernhard

    2017-01-01

    The aging of reinforced concrete infrastructure in developed countries imposes an urgent need for methods to reliably assess the condition of these structures. Corrosion of the embedded reinforcing steel is the most frequent cause for degradation. While it is well known that the ability of a structure to withstand corrosion depends strongly on factors such as the materials used or the age, it is common practice to rely on threshold values stipulated in standards or textbooks. These threshold values for corrosion initiation (Ccrit) are independent of the actual properties of a certain structure, which clearly limits the accuracy of condition assessments and service life predictions. The practice of using tabulated values can be traced to the lack of reliable methods to determine Ccrit on-site and in the laboratory. Here, an experimental protocol to determine Ccrit for individual engineering structures or structural members is presented. A number of reinforced concrete samples are taken from structures and laboratory corrosion testing is performed. The main advantage of this method is that it ensures real conditions concerning parameters that are well known to greatly influence Ccrit, such as the steel-concrete interface, which cannot be representatively mimicked in laboratory-produced samples. At the same time, the accelerated corrosion test in the laboratory permits the reliable determination of Ccrit prior to corrosion initiation on the tested structure; this is a major advantage over all common condition assessment methods that only permit estimating the conditions for corrosion after initiation, i.e., when the structure is already damaged. The protocol yields the statistical distribution of Ccrit for the tested structure. This serves as a basis for probabilistic prediction models for the remaining time to corrosion, which is needed for maintenance planning. This method can potentially be used in material testing of civil infrastructures, similar to established

  10. Experimental Protocol to Determine the Chloride Threshold Value for Corrosion in Samples Taken from Reinforced Concrete Structures.

    PubMed

    Angst, Ueli M; Boschmann, Carolina; Wagner, Matthias; Elsener, Bernhard

    2017-08-31

    The aging of reinforced concrete infrastructure in developed countries imposes an urgent need for methods to reliably assess the condition of these structures. Corrosion of the embedded reinforcing steel is the most frequent cause for degradation. While it is well known that the ability of a structure to withstand corrosion depends strongly on factors such as the materials used or the age, it is common practice to rely on threshold values stipulated in standards or textbooks. These threshold values for corrosion initiation (Ccrit) are independent of the actual properties of a certain structure, which clearly limits the accuracy of condition assessments and service life predictions. The practice of using tabulated values can be traced to the lack of reliable methods to determine Ccrit on-site and in the laboratory. Here, an experimental protocol to determine Ccrit for individual engineering structures or structural members is presented. A number of reinforced concrete samples are taken from structures and laboratory corrosion testing is performed. The main advantage of this method is that it ensures real conditions concerning parameters that are well known to greatly influence Ccrit, such as the steel-concrete interface, which cannot be representatively mimicked in laboratory-produced samples. At the same time, the accelerated corrosion test in the laboratory permits the reliable determination of Ccrit prior to corrosion initiation on the tested structure; this is a major advantage over all common condition assessment methods that only permit estimating the conditions for corrosion after initiation, i.e., when the structure is already damaged. The protocol yields the statistical distribution of Ccrit for the tested structure. This serves as a basis for probabilistic prediction models for the remaining time to corrosion, which is needed for maintenance planning. This method can potentially be used in material testing of civil infrastructures, similar to established

  11. Numerical and experimental research on pentagonal cross-section of the averaging Pitot tube

    NASA Astrophysics Data System (ADS)

    Zhang, Jili; Li, Wei; Liang, Ruobing; Zhao, Tianyi; Liu, Yacheng; Liu, Mingsheng

    2017-07-01

    Averaging Pitot tubes have been widely used in many fields because of their simple structure and stable performance. This paper introduces a new shape of the cross-section of an averaging Pitot tube. Firstly, the structure of the averaging Pitot tube and the distribution of pressure taps are given. Then, a mathematical model of the airflow around it is formulated. After that, a series of numerical simulations are carried out to optimize the geometry of the tube. The distribution of the streamline and pressures around the tube are given. To test its performance, a test platform was constructed in accordance with the relevant national standards and is described in this paper. Curves are provided, linking the values of flow coefficient with the values of Reynolds number. With a maximum deviation of only  ±3%, the results of the flow coefficient obtained from the numerical simulations were in agreement with those obtained from experimental methods. The proposed tube has a stable flow coefficient and favorable metrological characteristics.

  12. Experimental investigation of supersonic low pressure air plasma flows obtained with different arc-jet operating conditions

    NASA Astrophysics Data System (ADS)

    Lago, Viviana; Ndiaye, Abdoul-Aziz

    2012-11-01

    A stationary arc-jet plasma flow at low pressure is used to simulate some properties of the gas flow surrounding a vehicle during its entry into celestial body's atmospheres. This paper presents an experimental study concerning plasmas simulating a re-entry into our planet. Optical measurements have been carried out for several operating plasma conditions in the free stream, and in the shock layer formed in front of a flat cylindrical plate, placed in the plasma jet. The analysis of the spectral radiation enabled the identification of the emitting species, the determination of the rotational and vibrational temperatures in the free-stream and in the shock layer and the determination of the distance of the shock to the flat plate face. Some plasma fluid parameters like, stagnation pressure, specific enthalpy and heat flux have been determined experimentally along the plasma-jet axis.

  13. Keratometry obtained by corneal mapping versus the IOLMaster in the prediction of postoperative refraction in routine cataract surgery.

    PubMed

    Dulku, Simon; Smith, Henry B; Antcliff, Richard J

    2013-01-01

    To establish whether simulated keratometry values obtained by corneal mapping (videokeratography) would provide a superior refractive outcome to those obtained by Zeiss IOLMaster (partial coherence interferometry) in routine cataract surgery. Prospective, non-randomized, single-surgeon study set at the The Royal United Hospital, Bath, UK, District General Hospital. Thirty-three patients undergoing routine cataract surgery in the absence of significant ocular comorbidity. Conventional biometry was recorded using the Zeiss IOLMaster. Postoperative refraction was calculated using the SRK/T formula and the most appropriate power of lens implanted. Preoperative keratometry values were also obtained using Humphrey Instruments Atlas Version A6 corneal mapping. Achieved refraction was compared with predicted refraction for the two methods of keratometry after the A-constants were optimized to obtain a mean arithmetic error of zero dioptres for each device. The mean absolute prediction error was 0.39 dioptres (standard deviation 0.29) for IOLMaster and 0.48 dioptres (standard deviation 0.31) for corneal mapping (P = 0.0015). Keratometry readings between the devices were highly correlated by Spearman correlation (0.97). The Bland-Altman plot demonstrated close agreement between keratometers, with a bias of 0.0079 dioptres and 95% limits of agreement of -0.48-0.49 dioptres. The IOLMaster was superior to Humphrey Atlas A6 corneal mapping in the prediction of postoperative refraction. This difference could not have been predicted from the keratometry readings alone. When comparing biometry devices, close agreement between readings should not be considered a substitute for actual postoperative refraction data. © 2012 The Authors. Clinical and Experimental Ophthalmology © 2012 Royal Australian and New Zealand College of Ophthalmologists.

  14. Experimental and theoretical studies of Sub-THz detection using strained-Si FETs

    NASA Astrophysics Data System (ADS)

    Delgado Notario, J. A.; Javadi, E.; Clericò, V.; Fobelets, K.; Otsuji, T.; Diez, E.; Velázquez-Pérez, J. E.; Meziani, Y. M.

    2017-10-01

    We report on experimental and theoretical studies of nanoscale gate-lengths strained Silicon MODFETs as room temperature non resonant detectors. Devices were excited at room temperature by an electronic source at 150 and 300 GHz to characterize their sub-THz response. The maximum of the photovoltaic response was obtained when the FET gate was biased at a value close to the threshold voltage. Simulations based on a bi-dimensional hydrodynamic model for the charge transport coupled to a Poisson equation solver were performed by using Synopsys TCAD. A charge boundary condition for the floating drain contact was implemented to obtain the photovoltaic response. Results from numerical simulations are in agreement with experimental ones. To understand the coupling between terahertz radiation and devices, the devices were rotated at different angles under excitation at both sub-terahertz frequencies and their response measured. Both NEP (Noise Equivalent Power) and Responsivity were calculated from measurements. To demonstrate their utility, devices were used as sensors in a terahertz imaging system for inspection of hidden objects at both frequencies.

  15. Probability Analysis of the Wave-Slamming Pressure Values of the Horizontal Deck with Elastic Support

    NASA Astrophysics Data System (ADS)

    Zuo, Weiguang; Liu, Ming; Fan, Tianhui; Wang, Pengtao

    2018-06-01

    This paper presents the probability distribution of the slamming pressure from an experimental study of regular wave slamming on an elastically supported horizontal deck. The time series of the slamming pressure during the wave impact were first obtained through statistical analyses on experimental data. The exceeding probability distribution of the maximum slamming pressure peak and distribution parameters were analyzed, and the results show that the exceeding probability distribution of the maximum slamming pressure peak accords with the three-parameter Weibull distribution. Furthermore, the range and relationships of the distribution parameters were studied. The sum of the location parameter D and the scale parameter L was approximately equal to 1.0, and the exceeding probability was more than 36.79% when the random peak was equal to the sample average during the wave impact. The variation of the distribution parameters and slamming pressure under different model conditions were comprehensively presented, and the parameter values of the Weibull distribution of wave-slamming pressure peaks were different due to different test models. The parameter values were found to decrease due to the increased stiffness of the elastic support. The damage criterion of the structure model caused by the wave impact was initially discussed, and the structure model was destroyed when the average slamming time was greater than a certain value during the duration of the wave impact. The conclusions of the experimental study were then described.

  16. The guanidine and maleic acid (1:1) complex. The additional theoretical and experimental studies.

    PubMed

    Drozd, Marek; Dudzic, Damian

    2012-04-01

    On the basis of experimental literature data the theoretical studies for guanidinium and maleic acid complex with using DFT method are performed. In these studies the experimental X-ray data for two different forms of investigated crystal were used. During the geometry optimization process one equilibrium structure was found, only. According to this result the infrared spectrum for one theoretical molecule was calculated. On the basis of potential energy distribution (PED) analysis the clear-cut assignments of observed bands were performed. For the calculated molecule with energy minimum the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) were obtained and graphically illustrated. The energy difference (GAP) between HOMO and LUMO was analyzed. Additionally, the nonlinear properties of this molecule were calculated. The α and β (first and second order) hyperpolarizability values are obtained. On the basis of these results the title crystal was classified as new second order NLO generator. Copyright © 2011 Elsevier B.V. All rights reserved.

  17. Experimental research of kinetic and dynamic characteristics of temperature movements of machines

    NASA Astrophysics Data System (ADS)

    Parfenov, I. V.; Polyakov, A. N.

    2018-03-01

    Nowadays, the urgency of informational support of machines at different stages of their life cycle is increasing in the form of various experimental characteristics that determine the criteria for working capacity. The effectiveness of forming the base of experimental characteristics of machines is related directly to the duration of their field tests. In this research, the authors consider a new technique that allows reducing the duration of full-scale testing of machines by 30%. To this end, three new indicator coefficients were calculated in real time to determine the moments corresponding to the characteristic points. In the work, new terms for thermal characteristics of machine tools are introduced: kinetic and dynamic characteristics of the temperature movements of the machine. This allow taking into account not only the experimental values for the temperature displacements of the elements of the carrier system of the machine, but also their derivatives up to the third order, inclusively. The work is based on experimental data obtained in the course of full-scale thermal tests of a drilling-milling and boring CNC machine.

  18. Dehydroxylation and diagenetic variations in diatom oxygen isotope values

    NASA Astrophysics Data System (ADS)

    Dodd, Justin P.; Wiedenheft, Wilson; Schwartz, Joshua M.

    2017-02-01

    Numerous studies have documented changes in the dissolution and reactivity of biogenic silica as it is transferred from the water column to sediment archives; here we present the first experimental data that demonstrate a physical mechanism by which the oxygen isotope (δ18Osil) values of biogenic silica (diatoms) are altered during early diagenesis. The δ18Osil value of diatom silica cultured at 19.3 °C was +31.9‰ ± 0.2‰ (n = 6); the same silica experimentally aged in an artificial seawater media at near silica saturation at 85 °C had an average δ18Osil value of +27.1‰ ± 0.6‰ (n = 20). The most significant change in the δ18Osil value was coincident with an initial reduction in the total silanol abundance, indicating that the timing of dehydroxylation reactions in natural sedimentary environments is associated with diagenetic changes in the recorded δ18Osil values. The rate of change in the experimental aging environment at 85 °C was rapid, with significant changes in both silanol abundance and δ18Osil values. Additionally, the silica-water fractionation relationship recorded by the experimentally-aged samples approaches the equilibrium quartz-water fractionation factor. The linear rate law was used to estimate the timing of these changes in low temperature environments; the initial and most significant change in silica reactivity and δ18Osil values is likely to occur on the order of 10's of years at 4 °C. Published silica-water fractionation factors for sedimentary diatoms most likely represent a combination of growth and diagenetic environments, and the δ18O value of diagenetic water needs to be addressed when using δ18Osil values to reconstruct paleoceanographic and paleoenvironmental conditions.

  19. Temperature and pressure dependences of kimberlite melts viscosity (experimental-theoretical study)

    NASA Astrophysics Data System (ADS)

    Persikov, Eduard; Bykhtiyarov, Pavel; Cokol, Alexsander

    2016-04-01

    Experimental data on temperature and pressure dependences of viscosity of model kimberlite melts (silicate 82 + carbonate 18, wt. %, 100NBO/T = 313) have been obtained for the first time at 100 MPa of CO2 pressure and at the lithostatic pressures up to 7.5 GPa in the temperature range 1350 oC - 1950 oC using radiation high gas pressure apparatus and press free split-sphere multi - anvil apparatus (BARS). Experimental data obtained on temperature and pressure dependences of viscosity of model kimberlite melts at moderate and high pressures is compared with predicted data on these dependences of viscosity of basaltic melts (100NBO/T = 58) in the same T, P - range. Dependences of the viscosity of model kimberlite and basaltic melts on temperature are consistent to the exponential Arrenian equation in the T, P - range of experimental study. The correct values of activation energies of viscous flow of kimberlite melts have been obtained for the first time. The activation energies of viscous flow of model kimberlite melts exponentially increase with increasing pressure and are equal: E = 130 ± 1.3 kJ/mole at moderate pressure (P = 100 MPa) and E = 160 ± 1.6 kJ/mole at high pressure (P = 5.5 GPa). It has been established too that the viscosity of model kimberlite melts exponentially increases on about half order of magnitude with increasing pressures from 100 MPa to 7.5 GPa at the isothermal condition (1800 oC). It has been established that viscosity of model kimberlite melts at the moderate pressure (100 MPa) is lover on about one order of magnitude to compare with the viscosity of basaltic melts, but at high pressure range (5.5 - 7.5 GPa), on the contrary, is higher on about half order of magnitude at the same values of the temperatures. Here we use both a new experimental data on viscosity of kimberlite melts and our structural chemical model for calculation and prediction the viscosity of magmatic melts [1] to determine the fundamental features of viscosity of

  20. Normal Values of Tissue-Muscle Perfusion Indexes of Lower Limbs Obtained with a Scintigraphic Method.

    PubMed

    Manevska, Nevena; Stojanoski, Sinisa; Pop Gjorceva, Daniela; Todorovska, Lidija; Miladinova, Daniela; Zafirova, Beti

    2017-09-01

    Introduction Muscle perfusion is a physiologic process that can undergo quantitative assessment and thus define the range of normal values of perfusion indexes and perfusion reserve. The investigation of the microcirculation has a crucial role in determining the muscle perfusion. Materials and method The study included 30 examinees, 24-74 years of age, without a history of confirmed peripheral artery disease and all had normal findings on Doppler ultrasonography and pedo-brachial index of lower extremity (PBI). 99mTc-MIBI tissue muscle perfusion scintigraphy of lower limbs evaluates tissue perfusion in resting condition "rest study" and after workload "stress study", through quantitative parameters: Inter-extremity index (for both studies), left thigh/right thigh (LT/RT) left calf/right calf (LC/RC) and perfusion reserve (PR) for both thighs and calves. Results In our investigated group we assessed the normal values of quantitative parameters of perfusion indexes. Indexes ranged for LT/RT in rest study 0.91-1.05, in stress study 0.92-1.04. LC/RC in rest 0.93-1.07 and in stress study 0.93-1.09. The examinees older than 50 years had insignificantly lower perfusion reserve of these parameters compared with those younger than 50, LC (p=0.98), and RC (p=0.6). Conclusion This non-invasive scintigraphic method allows in individuals without peripheral artery disease to determine the range of normal values of muscle perfusion at rest and stress condition and to clinically implement them in evaluation of patients with peripheral artery disease for differentiating patients with normal from those with impaired lower limbs circulation.

  1. Study of Lightweight Ni-Co Alloy Mirrors Obtained by Electroforming Techniques

    NASA Technical Reports Server (NTRS)

    Jones, Ruth; Muntele, Iulia; Muntele, Claudiu; Zimmerman, Robert; Ila, Daryush; Smith, W. Scott (Technical Monitor)

    2002-01-01

    One contribution in reducing the costs of optics in space can be provided by production of ultralight mirrors. The decrease in the weight of the primary mirror of a telescope is anticipated to lead to the possibility of increasing the size of the telescopes, therefore increasing the amount and distance from which information is received. An electroplating process of ultralight replica mirrors from nickel sulfamate solution will be described. Based on an experimental setup with cylindrical symmetry, flat mirrors with a diameter of 7 inches and thickness of 1.5 mm are made from a Ni-Co alloy. The composition of the resulting deposit is analyzed using Rutherford Backscattering Spectrometry (RBS) and Proton Induced X-ray Emission (PIXE). In order to resolve Ni and Co, 10 MeV nitrogen ions are used as projectiles in the RBS measurements. Solution parameters monitored during the deposition process using optical absorption and polarography will be correlated with the final concentration of Ni and Co in the deposit. Bath parameters like temperature, current density, agitation level and acidity are chosen at certain values and maintained constant from one sample to another throughout the deposition process. The purpose of the experiment is to obtain mirrors with near zero stress, and predetermined composition and hardness. This study is an intermediate step in obtaining through the same process, but with a larger scale setup, ultralight large aperture replica mirrors.

  2. Comparison of the biometric values obtained by two different A-mode ultrasound devices (Eye Cubed vs. PalmScan): A Transversal, descriptive, and comparative study

    PubMed Central

    2010-01-01

    Background To assess the reliability of the measurements obtained with the PalmScan™, when compared with another standardized A-mode ultrasound device, and assess the consistency and correlation between the two methods. Methods Transversal, descriptive, and comparative study. We recorded the axial length (AL), anterior chamber depth (ACD) and lens thickness (LT) obtained with two A-mode ultrasounds (PalmScan™ A2000 and Eye Cubed™) using an immersion technique. We compared the measurements with a two-sample t-test. Agreement between the two devices was assessed with Bland-Altman plots and 95% limits of agreement. Results 70 eyes of 70 patients were enrolled in this study. The measurements with the Eye Cubed™ of AL and ACD were shorter than the measurements taken by the PalmScan™. The differences were not statistically significant regarding AL (p < 0.4) but significant regarding ACD (p < 0.001). The highest agreement between the two devices was obtained during LT measurement. The PalmScan™ measurements were shorter, but not statistically significantly (p < 0.2). Conclusions The values of AL and LT, obtained with both devices are not identical, but within the limits of agreement. The agreement is not affected by the magnitude of the ocular dimensions (but only between range of 20 mm to 27 mm of AL and 3.5 mm to 5.7 mm of LT). A correction of about 0.5 D could be considered if an intraocular lens is being calculated. However due to the large variability of the results, the authors recommend discretion in using this conversion factor, and to adjust the power of the intraocular lenses based upon the personal experience of the surgeon. PMID:20334670

  3. Comparison of the biometric values obtained by two different A-mode ultrasound devices (Eye Cubed vs. PalmScan): a transversal, descriptive, and comparative study.

    PubMed

    Velez-Montoya, Raul; Shusterman, Eugene Mark; López-Miranda, Miriam Jessica; Mayorquin-Ruiz, Mariana; Salcedo-Villanueva, Guillermo; Quiroz-Mercado, Hugo; Morales-Cantón, Virgilio

    2010-03-24

    To assess the reliability of the measurements obtained with the PalmScan, when compared with another standardized A-mode ultrasound device, and assess the consistency and correlation between the two methods. Transversal, descriptive, and comparative study. We recorded the axial length (AL), anterior chamber depth (ACD) and lens thickness (LT) obtained with two A-mode ultrasounds (PalmScan A2000 and Eye Cubed) using an immersion technique. We compared the measurements with a two-sample t-test. Agreement between the two devices was assessed with Bland-Altman plots and 95% limits of agreement. 70 eyes of 70 patients were enrolled in this study. The measurements with the Eye Cubed of AL and ACD were shorter than the measurements taken by the PalmScan. The differences were not statistically significant regarding AL (p < 0.4) but significant regarding ACD (p < 0.001). The highest agreement between the two devices was obtained during LT measurement. The PalmScan measurements were shorter, but not statistically significantly (p < 0.2). The values of AL and LT, obtained with both devices are not identical, but within the limits of agreement. The agreement is not affected by the magnitude of the ocular dimensions (but only between range of 20 mm to 27 mm of AL and 3.5 mm to 5.7 mm of LT). A correction of about 0.5 D could be considered if an intraocular lens is being calculated. However due to the large variability of the results, the authors recommend discretion in using this conversion factor, and to adjust the power of the intraocular lenses based upon the personal experience of the surgeon.

  4. Comparison with IRI-PLUS and IRI-2012-TEC values of GPS-TEC values

    NASA Astrophysics Data System (ADS)

    Atıcı, Ramazan; Saǧır, Selçuk

    2016-07-01

    This study presents a comparison with IRI-PLUS and IRI-2012 Total Electron Content (TEC) values of Total Electron Content (TEC) values obtained from Ankara station (39,7 N; 32,76 E) of Global Position System (GPS) of Turkey on equinox and solstice days of 2009 year. For all days, it is observed that GPS-TEC values are greater than IRI-2012-TEC values, while IRI-PLUS-TEC values are very close to GPS-TEC values. When GPS-TEC values for both equinoxes are compared, it is seen that TEC values on September equinox are greater than one on March equinox. However, it is observed that GPS-TEC values on June solstice are greater than one on December solstice. Also, the relationship between GPS-TEC values and geomagnetic indexes is investigated.

  5. Paraboloid Structured Silicon Surface for Enhanced Light Absorption: Experimental and Simulative Investigations

    NASA Astrophysics Data System (ADS)

    Khan, Firoz; Baek, Seong-Ho; Kaur, Jasmeet; Fareed, Imran; Mobin, Abdul; Kim, Jae Hyun

    2015-09-01

    In this paper, we present an optical model that simulates the light trapping and scattering effects of a paraboloid texture surface first time. This model was experimentally verified by measuring the reflectance values of the periodically textured silicon (Si) surface with the shape of a paraboloid under different conditions. A paraboloid texture surface was obtained by electrochemical etching Si in the solution of hydrofluoric acid, dimethylsulfoxide (DMSO), and deionized (DI) water. The paraboloid texture surface has the advantage of giving a lower reflectance value than the hemispherical, random pyramidal, and regular pyramidal texture surfaces. In the case of parabola, the light can be concentrated in the direction of the Si surface compared to the hemispherical, random pyramidal, and regular pyramidal textured surfaces. Furthermore, in a paraboloid textured surface, there can be a maximum value of 4 or even more by anisotropic etching duration compared to the hemispherical or pyramidal textured surfaces which have a maximum h/ D (depth and diameter of the texture) value of 0.5. The reflectance values were found to be strongly dependent on the h/ D ratio of the texture surface. The measured reflectance values were well matched with the simulated ones. The minimum reflectance value of ~4 % was obtained at a wavelength of 600 nm for an h/ D ratio of 3.75. The simulation results showed that the reflectance value for the h/ D ratio can be reduced to ~0.5 % by reducing the separations among the textures. This periodic paraboloidal structure can be applied to the surface texturing technique by substituting with a conventional pyramid textured surface or moth-eye antireflection coating.

  6. Experimental testing and constitutive modeling of the mechanical properties of the swine skin tissue.

    PubMed

    Łagan, Sylwia D; Liber-Kneć, Aneta

    2017-01-01

    The aim of the study was an estimation of the possibility of using hyperelastic material models to fit experimental data obtained in the tensile test for the swine skin tissue. The uniaxial tensile tests of samples taken from the abdomen and back of a pig was carried out. The mechanical properties of the skin such as the mean Young's modulus, the mean maximum stress and the mean maximum elongation were calculated. The experimental data have been used to identify the parameters in specific strain-energy functions given in seven constitutive models of hyperelastic materials: neo-Hookean, Mooney-Rivlin, Ogden, Yeoh, Martins, Humphrey and Veronda-Westmann. An analysis of errors in fitting of theoretical and experimental data was done. Comparison of load -displacement curves for the back and abdomen regions of skin taken showed a different scope of both the mean maximum loading forces and the mean maximum elongation. Samples which have been prepared from the abdominal area had lower values of the mean maximum load compared to samples from the spine area. The reverse trend was observed during the analysis of the values of elongation. An analysis of the accuracy of model fitting to the experimental data showed that, the least accurate were the model of neo- -Hookean, model of Mooney-Rivlin for the abdominal region and model of Veronda-Westmann for the spine region. An analysis of seven hyperelastic material models showed good correlations between the experimental and the theoretical data for five models.

  7. Direct Measurements of Quantum Kinetic Energy Tensor in Stable and Metastable Water near the Triple Point: An Experimental Benchmark.

    PubMed

    Andreani, Carla; Romanelli, Giovanni; Senesi, Roberto

    2016-06-16

    This study presents the first direct and quantitative measurement of the nuclear momentum distribution anisotropy and the quantum kinetic energy tensor in stable and metastable (supercooled) water near its triple point, using deep inelastic neutron scattering (DINS). From the experimental spectra, accurate line shapes of the hydrogen momentum distributions are derived using an anisotropic Gaussian and a model-independent framework. The experimental results, benchmarked with those obtained for the solid phase, provide the state of the art directional values of the hydrogen mean kinetic energy in metastable water. The determinations of the direction kinetic energies in the supercooled phase, provide accurate and quantitative measurements of these dynamical observables in metastable and stable phases, that is, key insight in the physical mechanisms of the hydrogen quantum state in both disordered and polycrystalline systems. The remarkable findings of this study establish novel insight into further expand the capacity and accuracy of DINS investigations of the nuclear quantum effects in water and represent reference experimental values for theoretical investigations.

  8. Time and temperature dependent breakdown characteristics of ZnS:Mn films obtained by rf-magnetron sputtering

    NASA Astrophysics Data System (ADS)

    Zhigal'Skii, A. A.; Mukhachev, V. A.; Troyan, P. E.

    1994-04-01

    Breakdown delay times (tdel) for films of managanese-doped zinc sulfide (ZnS:Mn) were measured in the range 10-6-10-1 s. The maximum value was tdel=10-3-10-2 s. The electrical strength (Ebr) was found to increase as the voltage pulse duration was reduced, the more so the thinner the ZnS:Mn film. The temperature dependence of Ebr exhibited a weak reduction in Ebr as the temperature was raised to roughly 80°C and a sharp reduction in Ebr for T>130°C. A maximum in Ebr was observed at T≈130°C which is presumably explained by a structural modification of the ZnS:Mn film. The experimental results obtained are explained in terms of a combined electronic and thermal breakdown mechanism.

  9. Experimental study on visual detection for fatigue of fixed-position staff.

    PubMed

    Nie, Baisheng; Huang, Xin; Chen, Yang; Li, Anjin; Zhang, Ruming; Huang, Jinxin

    2017-11-01

    Fatigue can lead to decreased work performance and poorer safety and health condition. Fatigue is ubiquitous in production and in life, while the research on it is mainly concentrated in the automotive driving, aircraft piloting and other fields, and it is insufficient to study on the fatigue of fixed-position staff. This paper puts forward a non-contact visual image method, which can monitor the extent of fatigue of fixed-position staff. Fatigue threshold used in judgment is obtained by processing the recorded data of visual images of the experimental subjects when fatiguing and by analyzing eye closure time, percentage of eyelid closure (PERCLOS) value, frequency and number of blinks. The results show that there is significant difference among the four indicators before and after experiment subjects undergo fatigue. The fatigue of experimental subjects is obvious when eye closure time is 3.5 s/min, PERCLOS value 6%, and blink frequency 0.4 times/s. This provides a reference for a wider range of detection of fatigue and a method for avoiding mistakes and accidents. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Inappropriate fiddling with statistical analyses to obtain a desirable p-value: tests to detect its presence in published literature.

    PubMed

    Gadbury, Gary L; Allison, David B

    2012-01-01

    Much has been written regarding p-values below certain thresholds (most notably 0.05) denoting statistical significance and the tendency of such p-values to be more readily publishable in peer-reviewed journals. Intuition suggests that there may be a tendency to manipulate statistical analyses to push a "near significant p-value" to a level that is considered significant. This article presents a method for detecting the presence of such manipulation (herein called "fiddling") in a distribution of p-values from independent studies. Simulations are used to illustrate the properties of the method. The results suggest that the method has low type I error and that power approaches acceptable levels as the number of p-values being studied approaches 1000.

  11. A Microwave Radiometric Method to Obtain the Average Path Profile of Atmospheric Temperature and Humidity Structure Parameters and Its Application to Optical Propagation System Assessment

    NASA Technical Reports Server (NTRS)

    Manning, Robert M.; Vyhnalek, Brian E.

    2015-01-01

    The values of the key atmospheric propagation parameters Ct2, Cq2, and Ctq are highly dependent upon the vertical height within the atmosphere thus making it necessary to specify profiles of these values along the atmospheric propagation path. The remote sensing method suggested and described in this work makes use of a rapidly integrating microwave profiling radiometer to capture profiles of temperature and humidity through the atmosphere. The integration times of currently available profiling radiometers are such that they are approaching the temporal intervals over which one can possibly make meaningful assessments of these key atmospheric parameters. Since these parameters are fundamental to all propagation conditions, they can be used to obtain Cn2 profiles for any frequency, including those for an optical propagation path. In this case the important performance parameters of the prevailing isoplanatic angle and Greenwood frequency can be obtained. The integration times are such that Kolmogorov turbulence theory and the Taylor frozen-flow hypothesis must be transcended. Appropriate modifications to these classical approaches are derived from first principles and an expression for the structure functions are obtained. The theory is then applied to an experimental scenario and shows very good results.

  12. Experimental and computational study on the molecular energetics of indoline and indole.

    PubMed

    da Silva, Manuel A V Ribeiro; Cabral, Joana I T A; Gomes, José R B

    2008-11-27

    Static bomb calorimetry, Calvet microcalorimetry and the Knudsen effusion technique were used to determine the standard molar enthalpy of formation in the gas phase, at T = 298.15 K, of the indole and indoline heterocyclic compounds. The values obtained were 164.3 +/- 1.3 kJ x mol(-1) and 120.0 +/- 2.9 kJ x mol(-1), respectively. Several different computational approaches and different working reactions were used to estimate the gas-phase enthalpies of formation for indole and indoline. The computational approaches support the experimental results reported. The calculations were further extended to the determination of other properties such as bond dissociation enthalpies, gas-phase acidities, proton and electron affinities and ionization energies. The agreement between theoretical and experimental data for indole is very good supporting the data calculated for indoline.

  13. Reproductive biology of Lutzomyia shannoni (Dyar) (Diptera: Psychodidae) under experimental conditions.

    PubMed

    Cárdenas, E; Ferro, C; Corredor, D; Martínez, O; Munstermann, L E

    1999-12-01

    Baseline biological growth data of Lutzomyia shannoni (Dyar) were compared under two experimental conditions within insulated styrofoam chests and in standard laboratory incubators. The developmental time from egg to adult was 67 and 52 days, respectively. Based on cohorts of 100 females in each experiment, horizontal life tables were constructed. The following predictive parameters were obtained under each of the two conditions: net rate of reproduction (23.5 and 18.0 females per cohort female), generation time (11.4 and 9.4 weeks), intrinsic rate of population increase (0.27 and 0.30), and finite rate of population increment (1.31 and 1.36). The reproductive value for each class age of the cohort females was calculated. The observed parameters were obtained under each experimental condition: net rate of reproduction (1.9 and 2.5 females per cohort female), generation time (11.7 and 9.6 weeks), intrinsic rate of population increase (0.05 and 0.09), and finite rate of population increment (1.06 and 1.10). Vertical life tables were elaborated and mortality was described for every generation in each cohort. In addition, for two successive generations, additive variance and heritability for fecundity were estimated.

  14. Evaluated Mean Values and Covariances for the Prompt Fission Neutron Spectrum of 239Pu induced by neutrons of 500 keV

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neudecker, Denise

    2014-07-10

    This document provides the numerical values of the evaluated prompt fission neutron spectrum for 239Pu induced by neutrons of 500 keV as well as relative uncertainties and correlations. This document also contains a short description how these data were obtained and shows plots comparing the evaluated results to experimental information as well as the corresponding ENDF/B-VII.1 evaluation.

  15. Hypersonic nozzle/afterbody CFD code validation. I - Experimental measurements

    NASA Technical Reports Server (NTRS)

    Spaid, Frank W.; Keener, Earl R.

    1993-01-01

    This study was conducted to obtain a detailed experimental description of the flow field created by the interaction of a single-expansion-ramp-nozzle flow with a hypersonic external stream. Data were obtained from a generic nozzle/afterbody model in the 3.5-Foot Hypersonic Wind Tunnel of the NASA Ames Research Center in a cooperative experimental program involving Ames and the McDonnell Douglas Research Laboratories. This paper presents experimental results consisting primarily of surveys obtained with a five-hole total-pressure/flow-direction probe and a total-temperature probe. These surveys were obtained in the flow field created by the interaction between the underexpanded jet plume and the external flow.

  16. High Throughput Experimental Materials Database

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zakutayev, Andriy; Perkins, John; Schwarting, Marcus

    The mission of the High Throughput Experimental Materials Database (HTEM DB) is to enable discovery of new materials with useful properties by releasing large amounts of high-quality experimental data to public. The HTEM DB contains information about materials obtained from high-throughput experiments at the National Renewable Energy Laboratory (NREL).

  17. Vibrational properties of gold nanoparticles obtained by green synthesis

    NASA Astrophysics Data System (ADS)

    Alvarez, Ramón A. B.; Cortez-Valadez, M.; Bueno, L. Oscar Neira; Britto Hurtado, R.; Rocha-Rocha, O.; Delgado-Beleño, Y.; Martinez-Nuñez, C. E.; Serrano-Corrales, Luis Ivan; Arizpe-Chávez, H.; Flores-Acosta, M.

    2016-10-01

    This study reports the synthesis and characterization of gold nanoparticles through an ecological method to obtain nanostructures from the extract of the plant Opuntia ficus-indica. Colloidal nanoparticles show sizes that vary between 10-20 nm, and present various geometric morphologies. The samples were characterized through optical absorption, Raman Spectroscopy and Transmission Electron Microscopy (TEM). Additionally, low energy metallic clusters of Aun (n=2-20 atoms) were modeled by computational quantum chemistry. The theoretical results were obtained with Density Functional Theory (DFT). The predicted results of Au clusters show a tendency and are correlated with the experimental results concerning the optical absorption bands and Raman spectroscopy in gold nanoparticles.

  18. Optimal Experimental Design for Model Discrimination

    PubMed Central

    Myung, Jay I.; Pitt, Mark A.

    2009-01-01

    Models of a psychological process can be difficult to discriminate experimentally because it is not easy to determine the values of the critical design variables (e.g., presentation schedule, stimulus structure) that will be most informative in differentiating them. Recent developments in sampling-based search methods in statistics make it possible to determine these values, and thereby identify an optimal experimental design. After describing the method, it is demonstrated in two content areas in cognitive psychology in which models are highly competitive: retention (i.e., forgetting) and categorization. The optimal design is compared with the quality of designs used in the literature. The findings demonstrate that design optimization has the potential to increase the informativeness of the experimental method. PMID:19618983

  19. Dose Distribution in Cone-Beam Breast Computed Tomography: An Experimental Phantom Study

    NASA Astrophysics Data System (ADS)

    Russo, Paolo; Lauria, Adele; Mettivier, Giovanni; Montesi, Maria Cristina; Villani, Natalia

    2010-02-01

    We measured the spatial distribution of absorbed dose in a 14 cm diameter PMMA half-ellipsoid phantom simulating the uncompressed breast, using an X-ray cone-beam breast computed tomography apparatus, assembled for laboratory tests. Thermoluminescent dosimeters (TLD-100) were placed inside the phantom in six positions, both axially and at the phantom periphery. To study the dose distribution inside the PMMA phantom two experimental setups were adopted with effective energies in the range 28.7-44.4 keV. Different values of effective energies were obtained by combining different configurations of added Cu filtration (0.05 mm or 0.2 mm) and tube voltages (from 50 kVp to 80 kVp). Dose values obtained by TLDs in different positions inside the PMMA are reported. To evaluate the dose distribution in the breast shaped volume, the values measured were normalized to the one obtained in the inner position inside the phantom. Measurements with a low energy setup show a gradual increment of dose going from the "chest wall" to the "nipple" (63% more at the "nipple" compared to the central position). Likewise, a gradual increment is observed going from the breast axis toward the periphery (82% more at the "skin" compared to the central position). A more uniform distribution of dose inside the PMMA was obtained with a high energy setup (the maximum variation was 33% at 35.5 keV effective energy in the radial direction). The most uniform distribution is obtained at 44.4 keV. The results of this study show how the dose is distributed: it varies as a function of effective energy of the incident X-ray beam and as a function of the position inside the volume (axial or peripheral position).

  20. The essential value of long-term experimental data for hydrology and water management

    NASA Astrophysics Data System (ADS)

    Tetzlaff, Doerthe; Carey, Sean K.; McNamara, James P.; Laudon, Hjalmar; Soulsby, Chris

    2017-04-01

    Observations and data from long-term experimental watersheds are the foundation of hydrology as a geoscience. They allow us to benchmark process understanding, observe trends and natural cycles, and are prerequisites for testing predictive models. Long-term experimental watersheds also are places where new measurement technologies are developed. These studies offer a crucial evidence base for understanding and managing the provision of clean water supplies, predicting and mitigating the effects of floods, and protecting ecosystem services provided by rivers and wetlands. They also show how to manage land and water in an integrated, sustainable way that reduces environmental and economic costs.

  1. Experimental determination of the dynamics of an acoustically levitated sphere

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pérez, Nicolás, E-mail: nico@fisica.edu.uy; Andrade, Marco A. B.; Canetti, Rafael

    2014-11-14

    Levitation of solids and liquids by ultrasonic standing waves is a promising technique to manipulate materials without contact. When a small particle is introduced in certain areas of a standing wave field, the acoustic radiation force pushes the particle to the pressure node. This movement is followed by oscillations of the levitated particle. Aiming to investigate the particle oscillations in acoustic levitation, this paper presents the experimental and numerical characterization of the dynamic behavior of a levitated sphere. To obtain the experimental response, a small sphere is lifted by the acoustic radiation force. After the sphere lift, it presents amore » damped oscillatory behavior, which is recorded by a high speed camera. To model this behavior, a mass-spring-damper system is proposed. In this model, the acoustic radiation force that acts on the sphere is theoretically predicted by the Gor'kov theory and the viscous forces are modeled by two damping terms, one term proportional to the square of the velocity and another term proportional to the particle velocity. The proposed model was experimentally verified by using different values of sound pressure amplitude. The comparison between numerical and experimental results shows that the model can accurately describe the oscillatory behavior of the sphere in an acoustic levitator.« less

  2. Experimental determination of the dynamics of an acoustically levitated sphere

    NASA Astrophysics Data System (ADS)

    Pérez, Nicolás; Andrade, Marco A. B.; Canetti, Rafael; Adamowski, Julio C.

    2014-11-01

    Levitation of solids and liquids by ultrasonic standing waves is a promising technique to manipulate materials without contact. When a small particle is introduced in certain areas of a standing wave field, the acoustic radiation force pushes the particle to the pressure node. This movement is followed by oscillations of the levitated particle. Aiming to investigate the particle oscillations in acoustic levitation, this paper presents the experimental and numerical characterization of the dynamic behavior of a levitated sphere. To obtain the experimental response, a small sphere is lifted by the acoustic radiation force. After the sphere lift, it presents a damped oscillatory behavior, which is recorded by a high speed camera. To model this behavior, a mass-spring-damper system is proposed. In this model, the acoustic radiation force that acts on the sphere is theoretically predicted by the Gor'kov theory and the viscous forces are modeled by two damping terms, one term proportional to the square of the velocity and another term proportional to the particle velocity. The proposed model was experimentally verified by using different values of sound pressure amplitude. The comparison between numerical and experimental results shows that the model can accurately describe the oscillatory behavior of the sphere in an acoustic levitator.

  3. Experimental Study of an Advanced Concept of Moderate-resolution Holographic Spectrographs

    NASA Astrophysics Data System (ADS)

    Muslimov, Eduard; Valyavin, Gennady; Fabrika, Sergei; Musaev, Faig; Galazutdinov, Gazinur; Pavlycheva, Nadezhda; Emelianov, Eduard

    2018-07-01

    We present the results of an experimental study of an advanced moderate-resolution spectrograph based on a cascade of narrow-band holographic gratings. The main goal of the project is to achieve a moderately high spectral resolution with R up to 5000 simultaneously in the 4300–6800 Å visible spectral range on a single standard CCD, together with an increased throughput. The experimental study consisted of (1) resolution and image quality tests performed using the solar spectrum, and (2) a total throughput test performed for a number of wavelengths using a calibrated lab monochromator. The measured spectral resolving power reaches values over R > 4000 while the experimental throughput is as high as 55%, which agrees well with the modeling results. Comparing the obtained characteristics of the spectrograph under consideration with the best existing spectrographs, we conclude that the used concept can be considered as a very competitive and cheap alternative to the existing spectrographs of the given class. We propose several astrophysical applications for the instrument and discuss the prospect of creating its full-scale version.

  4. Estimation of missing values in solar radiation data using piecewise interpolation methods: Case study at Penang city

    NASA Astrophysics Data System (ADS)

    Zainudin, Mohd Lutfi; Saaban, Azizan; Bakar, Mohd Nazari Abu

    2015-12-01

    The solar radiation values have been composed by automatic weather station using the device that namely pyranometer. The device is functions to records all the radiation values that have been dispersed, and these data are very useful for it experimental works and solar device's development. In addition, for modeling and designing on solar radiation system application is needed for complete data observation. Unfortunately, lack for obtained the complete solar radiation data frequently occur due to several technical problems, which mainly contributed by monitoring device. Into encountering this matter, estimation missing values in an effort to substitute absent values with imputed data. This paper aimed to evaluate several piecewise interpolation techniques likes linear, splines, cubic, and nearest neighbor into dealing missing values in hourly solar radiation data. Then, proposed an extendable work into investigating the potential used of cubic Bezier technique and cubic Said-ball method as estimator tools. As result, methods for cubic Bezier and Said-ball perform the best compare to another piecewise imputation technique.

  5. Influence of Fuel Moisture Content and Reactor Temperature on the Calorific Value of Syngas Resulted from Gasification of Oil Palm Fronds

    PubMed Central

    Atnaw, Samson Mekbib; Sulaiman, Shaharin Anwar; Yusup, Suzana

    2014-01-01

    Biomass wastes produced from oil palm mills and plantations include empty fruit bunches (EFBs), shells, fibers, trunks, and oil palm fronds (OPF). EFBs and shells are partially utilized as boiler fuel while the rest of the biomass materials like OPF have not been utilized for energy generation. No previous study has been reported on gasification of oil palm fronds (OPF) biomass for the production of fuel gas. In this paper, the effect of moisture content of fuel and reactor temperature on downdraft gasification of OPF was experimentally investigated using a lab scale gasifier of capacity 50 kW. In addition, results obtained from equilibrium model of gasification that was developed for facilitating the prediction of syngas composition are compared with experimental data. Comparison of simulation results for predicting calorific value of syngas with the experimental results showed a satisfactory agreement with a mean error of 0.1 MJ/Nm3. For a biomass moisture content of 29%, the resulting calorific value for the syngas was found to be only 2.63 MJ/Nm3, as compared to nearly double (4.95 MJ/Nm3) for biomass moisture content of 22%. A calorific value as high as 5.57 MJ/Nm3 was recorded for higher oxidation zone temperature values. PMID:24578617

  6. Experimental study on flow boiling heat transfer of LNG in a vertical smooth tube

    NASA Astrophysics Data System (ADS)

    Chen, Dongsheng; Shi, Yumei

    2013-10-01

    An experimental apparatus is set up in this work to study the upward flow boiling heat transfer characteristics of LNG (liquefied natural gas) in vertical smooth tubes with inner diameters of 8 mm and 14 mm. The experiments were performed at various inlet pressures from 0.3 to 0.7 MPa. The results were obtained over the mass flux range from 16 to 200 kg m-2 s-1 and heat fluxes ranging from 8.0 to 32 kW m-2. The influences of quality, heat flux and mass flux, tube diameter on the heat transfer characteristic are examined and discussed. The comparisons of the experimental heat transfer coefficients with the predicted values from the existing correlations are analyzed. The correlation by Zou et al. [16] shows the best accuracy with the RMS deviation of 31.7% in comparison with the experimental data.

  7. Investigation of Properties of Nanocomposite Polyimide Samples Obtained by Fused Deposition Modeling

    NASA Astrophysics Data System (ADS)

    Polyakov, I. V.; Vaganov, G. V.; Yudin, V. E.; Ivan'kova, E. M.; Popova, E. N.; Elokhovskii, V. Yu.

    2018-03-01

    Nanomodified polyimide samples were obtained by fused deposition modeling (FDM) using an experimental setup for 3D printing of highly heat-resistant plastics. The mechanical properties and structure of these samples were studied by viscosimetry, differential scanning calorimetry, and scanning electron microscopy. A comparative estimation of the mechanical properties of laboratory samples obtained from a nanocomposite based on heat-resistant polyetherimide by FDM and injection molding is presented.

  8. Partitioned key-value store with atomic memory operations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bent, John M.; Faibish, Sorin; Grider, Gary

    A partitioned key-value store is provided that supports atomic memory operations. A server performs a memory operation in a partitioned key-value store by receiving a request from an application for at least one atomic memory operation, the atomic memory operation comprising a memory address identifier; and, in response to the atomic memory operation, performing one or more of (i) reading a client-side memory location identified by the memory address identifier and storing one or more key-value pairs from the client-side memory location in a local key-value store of the server; and (ii) obtaining one or more key-value pairs from themore » local key-value store of the server and writing the obtained one or more key-value pairs into the client-side memory location identified by the memory address identifier. The server can perform functions obtained from a client-side memory location and return a result to the client using one or more of the atomic memory operations.« less

  9. Optimization and kinetic modeling of esterification of the oil obtained from waste plum stones as a pretreatment step in biodiesel production.

    PubMed

    Kostić, Milan D; Veličković, Ana V; Joković, Nataša M; Stamenković, Olivera S; Veljković, Vlada B

    2016-02-01

    This study reports on the use of oil obtained from waste plum stones as a low-cost feedstock for biodiesel production. Because of high free fatty acid (FFA) level (15.8%), the oil was processed through the two-step process including esterification of FFA and methanolysis of the esterified oil catalyzed by H2SO4 and CaO, respectively. Esterification was optimized by response surface methodology combined with a central composite design. The second-order polynomial equation predicted the lowest acid value of 0.53mgKOH/g under the following optimal reaction conditions: the methanol:oil molar ratio of 8.5:1, the catalyst amount of 2% and the reaction temperature of 45°C. The predicted acid value agreed with the experimental acid value (0.47mgKOH/g). The kinetics of FFA esterification was described by the irreversible pseudo first-order reaction rate law. The apparent kinetic constant was correlated with the initial methanol and catalyst concentrations and reaction temperature. The activation energy of the esterification reaction slightly decreased from 13.23 to 11.55kJ/mol with increasing the catalyst concentration from 0.049 to 0.172mol/dm(3). In the second step, the esterified oil reacted with methanol (methanol:oil molar ratio of 9:1) in the presence of CaO (5% to the oil mass) at 60°C. The properties of the obtained biodiesel were within the EN 14214 standard limits. Hence, waste plum stones might be valuable raw material for obtaining fatty oil for the use as alternative feedstock in biodiesel production. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Beyond low beta-decay Q values

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mustonen, M. T.; Suhonen, J.

    Beta decays with low Q values can be utilized in the quest to determine the neutrino mass scale. This is being realized in two experiments, KATRIN and MARE, using tritium and {sup 187}Re, respectively. The beta-decay of {sup 187}Re had the lowest known Q value until 2005, when the beta decay of {sup 115}In to the first excited state of {sup 115}Sn was discovered in Gran Sasso underground laboratory. Last year two independent ion trap measurements confirmed that this decay breaks the former record by an order of magnitude.Our theoretical study on this tiny decay channel complemented the experimental effortmore » by the JYFLTRAP group in Finland and HADES underground laboratory in Belgium. A significant discrepancy between the experimental and theoretical results was found. This might be explained by various atomic contributions known to grow larger as the Q value decreases. However, the traditional recipes for taking these effects into account break down on this new ultra-low Q value regime, providing new challenges for theorists on the borderline between nuclear and atomic physics.« less

  11. Mechanical properties of experimental composites with different calcium phosphates fillers.

    PubMed

    Okulus, Zuzanna; Voelkel, Adam

    2017-09-01

    Calcium phosphates (CaPs)-containing composites have already shown good properties from the point of view of dental restorative materials. The purpose of this study was to examine the crucial mechanical properties of twelve hydroxyapatite- or tricalcium phosphate-filled composites. The raw and surface-treated forms of both CaP fillers were applied. As a reference materials two experimental glass-containing composites and one commercial dental restorative composite were applied. Nano-hardness, elastic modulus, compressive, flexural and diametral tensile strength of all studied materials were determined. Application of statistical methods (one-way analysis of variance and cluster agglomerative analysis) allowed for assessing the similarities between examined materials according to the values of studied parameters. The obtained results show that in almost all cases the mechanical properties of experimental CaPs-composites are comparable or even better than mechanical properties of examined reference materials. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Antioxidative Categorization of Twenty Amino Acids Based on Experimental Evaluation.

    PubMed

    Xu, Naijin; Chen, Guanqun; Liu, Hui

    2017-11-27

    In view of the great importance bestowed on amino acids as antioxidants in oxidation resistance, we attempted two common redox titration methods in this report, including micro-potassium permanganate titration and iodometric titration, to measure the antioxidative capacity of 20 amino acids, which are the construction units of proteins in living organisms. Based on the relative intensities of the antioxidative capacity, we further conducted a quantitative comparison and found out that the product of experimental values obtained from the two methods was proven to be a better indicator for evaluating the relative antioxidative capacity of amino acids. The experimental results were largely in accordance with structural analysis made on amino acids. On the whole, the 20 amino acids concerned could be divided into two categories according to their antioxidative capacity. Seven amino acids, including tryptophan, methionine, histidine, lysine, cysteine, arginine and tyrosine, were greater in total antioxidative capacity compared with the other 13 amino acids.

  13. Turbulent Boundary Layers in Oscillating Flows. Part 1: an Experimental and Computational Study

    NASA Technical Reports Server (NTRS)

    Cook, W. J.

    1986-01-01

    An experimental-computational study of the behavior of turbulent boundary layers for oscillating air flows over a plane surface with a small favorable mean pressure gradient is described. Experimental studies were conducted for boundary layers generated on the test section wall of a facility that produces a flow with a mean free stream velocity and a superposed nearly-pure sinusoidal component over a wide range of frequency. Flow at a nominal mean free stream velocity of 50 m/s were studied at atmospheric pressure and temperature at selected axial positions over a 2 m test length for frequencies ranging from 4 to 29 Hz. Quantitative experimental results are presented for unsteady velocity profiles and longitudinal turbulence levels obtained from hot wire anemometer measurements at three axial positions. Mean velocity profiles for oscillating flows were found to exhibit only small deviations from corresponding steady flow profiles, while amplitudes and phase relationships exhibited a strong dependence on axial position and frequency. Since sinusoidal flows could be generated over a wide range of frequency, studies at fixed values of reduced frequency at different axial positions were studied. Results show that there is some utility in the use of reduced frequency to correlate unsteady velocity results. The turbulence level u' sub rms was observed to vary essentially sinusoidally around values close to those measured in steady flow. However, the amplitude of oscillation and phase relations for turbulence level were found to be strongly frequency dependent. Numerical predictions were obtained using an unsteady boundary layer computational code and the Cebeci-Smith and Glushko turbulence models. Predicted quantities related to unsteady velocity profiles exhibit fair agreement with experiment when the Cebeci-Smith turbulence model is used.

  14. Clinical utility of apparent diffusion coefficient values obtained using high b-value when diagnosing prostate cancer using 3 tesla MRI: comparison between ultra-high b-value (2000 s/mm²) and standard high b-value (1000 s/mm²).

    PubMed

    Kitajima, Kazuhiro; Takahashi, Satoru; Ueno, Yoshiko; Yoshikawa, Takeshi; Ohno, Yoshiharu; Obara, Makoto; Miyake, Hideaki; Fujisawa, Masato; Sugimura, Kazuro

    2012-07-01

    To determine whether the apparent diffusion coefficient (ADC) obtained using b = 2000 s/mm(2) upon 3 Tesla (T) diffusion-weighted MRI is superior to b = 1000 s/mm(2) for discriminating malignant from normal prostate tissue and predicting the aggressiveness of prostate cancer, using histopathological findings of radical prostatectomy as a reference. Eighty prostate cancer patients underwent preoperative 3T MRI including diffusion weighted imaging with b-values of 0, 1000, and 2000 s/mm(2) . ADCs were measured for malignant lesions and normal sites on three sets of ADC maps calculated with monoexponential fitting between b = 0 and 1000, 0 and 2000, and 1000 and 2000, respectively. The relationship between the ADC and Gleason score was evaluated. The areas under the ROC curves for b = 0,1000, b = 0,2000, and b = 1000,2000 were 0.896, 0.937, and 0.857, respectively, in the peripheral zone (PZ) and 0.877, 0.889, and 0.731, respectively, in the transition zone (TZ). The difference between b = 0,1000 and b = 0,2000 was significant in PZ (P = 0.033), but not in TZ (P = 0.84). Weak but significant negative correlations were identified between ADCs and Gleason score in both PZ and TZ cancer at b = 0,1000 and b = 0,2000 (r = -0.323 to -0.341). For 3T MRI, ADCs using b = 0,2000 are more accurate than b = 0,1000 for diagnosing PZ cancer, and as accurate for TZ cancer. Copyright © 2012 Wiley Periodicals, Inc.

  15. Comparison of results obtained with various sensors used to measure fluctuating quantities in jets.

    NASA Technical Reports Server (NTRS)

    Parthasarathy, S. P.; Massier, P. F.; Cuffel, R. F.

    1973-01-01

    An experimental investigation has been conducted to compare the results obtained with six different instruments that sense fluctuating quantities in free jets. These sensors are typical of those that have recently been used by various investigators who are engaged in experimental studies of jet noise. Intensity distributions and two-point correlations with space separation and time delay were obtained. The static pressure, density, and velocity fluctuations are well correlated over the entire cross section of the jet and the cross-correlations persist for several jet diameters along the flow direction. The eddies appear to be flattened in the flow direction by a ratio of 0.4.

  16. Inappropriate Fiddling with Statistical Analyses to Obtain a Desirable P-value: Tests to Detect its Presence in Published Literature

    PubMed Central

    Gadbury, Gary L.; Allison, David B.

    2012-01-01

    Much has been written regarding p-values below certain thresholds (most notably 0.05) denoting statistical significance and the tendency of such p-values to be more readily publishable in peer-reviewed journals. Intuition suggests that there may be a tendency to manipulate statistical analyses to push a “near significant p-value” to a level that is considered significant. This article presents a method for detecting the presence of such manipulation (herein called “fiddling”) in a distribution of p-values from independent studies. Simulations are used to illustrate the properties of the method. The results suggest that the method has low type I error and that power approaches acceptable levels as the number of p-values being studied approaches 1000. PMID:23056287

  17. Evaluation of quality of kefir from milk obtained from goats supplemented with a diet rich in bioactive compounds.

    PubMed

    Cais-Sokolińska, Dorota; Pikul, Jan; Wójtowski, Jacek; Danków, Romualda; Teichert, Joanna; Czyżak-Runowska, Grażyna; Bagnicka, Emilia

    2015-04-01

    The composition of bioactive components in dairy products depends on their content in raw milk and the processing conditions. The experimental material consisted of the milk of dairy goats supplemented with 120 g d(-1) per head of false flax cake. The aim of the study was to evaluate the quality of kefir produced from goat's milk with a higher content of bioactive components resulting from supplementation of the goats' diet with false flax cake. The administration of false flax cake to goats had a positive effect on the fatty acid profile of the raw milk, causing an increase in the proportion of polyunsaturated fatty acids (PUFA), including conjugated linoleic acid (CLA) and n-3 fatty acids. Their increased percentage was detected in the kefir after production as well as after storage. The processing value of the harvested milk did not differ from the qualitative characteristics of milk from goats of the control group. Increasing the proportion of bioactive components in goat's milk did not result in changes in the acidity, texture, colour, flavour, aroma or consistency of the kefir obtained. Milk and kefir obtained after the administration of false flax cake to goats contain bioactive components (PUFA including CLA, n-3 and monoenic trans fatty acids) in significant amounts. Kefir from experimental goat's milk did not differ in quality from kefir made from the milk of the control group. © 2014 Society of Chemical Industry.

  18. A Computational and Experimental Investigation of Shear Coaxial Jet Atomization

    NASA Technical Reports Server (NTRS)

    Ibrahim, Essam A.; Kenny, R. Jeremy; Walker, Nathan B.

    2006-01-01

    The instability and subsequent atomization of a viscous liquid jet emanated into a high-pressure gaseous surrounding is studied both computationally and experimentally. Liquid water issued into nitrogen gas at elevated pressures is used to simulate the flow conditions in a coaxial shear injector element relevant to liquid propellant rocket engines. The theoretical analysis is based on a simplified mathematical formulation of the continuity and momentum equations in their conservative form. Numerical solutions of the governing equations subject to appropriate initial and boundary conditions are obtained via a robust finite difference scheme. The computations yield real-time evolution and subsequent breakup characteristics of the liquid jet. The experimental investigation utilizes a digital imaging technique to measure resultant drop sizes. Data were collected for liquid Reynolds number between 2,500 and 25,000, aerodynamic Weber number range of 50-500 and ambient gas pressures from 150 to 1200 psia. Comparison of the model predictions and experimental data for drop sizes at gas pressures of 150 and 300 psia reveal satisfactory agreement particularly for lower values of investigated Weber number. The present model is intended as a component of a practical tool to facilitate design and optimization of coaxial shear atomizers.

  19. Indoor radon regulation using tabulated values of temporal radon variation.

    PubMed

    Tsapalov, Andrey; Kovler, Konstantin

    2018-03-01

    Mass measurements of indoor radon concentrations have been conducted for about 30 years. In most of the countries, a national reference/action/limit level is adopted, limiting the annual average indoor radon (AAIR) concentration. However, until now, there is no single and generally accepted international protocol for determining the AAIR with a known confidence interval, based on measurements of different durations. Obviously, as the duration of measurements increases, the uncertainty of the AAIR estimation decreases. The lack of the information about the confidence interval of the determined AAIR level does not allow correct comparison with the radon reference level. This greatly complicates development of an effective indoor radon measurement protocol and strategy. The paper proposes a general principle of indoor radon regulation, based on the simple criteria widely used in metrology, and introduces a new parameter - coefficient of temporal radon variation K V (t) that depends on the measurement duration and determines the uncertainty of the AAIR. An algorithm for determining K V (t) based on the results of annual continuous radon monitoring in experimental rooms is proposed. Included are indoor radon activity concentrations and equilibrium equivalent concentration (EEC) of radon progeny. The monitoring was conducted in 10 selected experimental rooms located in 7 buildings, mainly in the Moscow region (Russia), from 2006 to 2013. The experimental and tabulated values of K V (t) and also the values of the coefficient of temporal EEC variation depending on the mode and duration of the measurements were obtained. The recommendations to improve the efficiency and reliability of indoor radon regulation are given. The importance of taking into account the geological factors is discussed. The representativity of the results of the study is estimated and the approach for their verification is proposed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Analysis of exposure to electromagnetic fields in a healthcare environment: simulation and experimental study.

    PubMed

    de Miguel-Bilbao, Silvia; Martín, Miguel Angel; Del Pozo, Alejandro; Febles, Victor; Hernández, José A; de Aldecoa, José C Fernández; Ramos, Victoria

    2013-11-01

    Recent advances in wireless technologies have lead to an increase in wireless instrumentation present in healthcare centers. This paper presents an analytical method for characterizing electric field (E-field) exposure within these environments. The E-field levels of the different wireless communications systems have been measured in two floors of the Canary University Hospital Consortium (CUHC). The electromagnetic (EM) conditions detected with the experimental measures have been estimated using the software EFC-400-Telecommunications (Narda Safety Test Solutions, Sandwiesenstrasse 7, 72793 Pfullingen, Germany). The experimental and simulated results are represented through 2D contour maps, and have been compared with the recommended safety and exposure thresholds. The maximum value obtained is much lower than the 3 V m(-1) that is established in the International Electrotechnical Commission Standard of Electromedical Devices. Results show a high correlation in terms of E-field cumulative distribution function (CDF) between the experimental and simulation results. In general, the CDFs of each pair of experimental and simulated samples follow a lognormal distribution with the same mean.

  1. Estimation of Δ R/ R values by benchmark study of the Mössbauer Isomer shifts for Ru, Os complexes using relativistic DFT calculations

    NASA Astrophysics Data System (ADS)

    Kaneko, Masashi; Yasuhara, Hiroki; Miyashita, Sunao; Nakashima, Satoru

    2017-11-01

    The present study applies all-electron relativistic DFT calculation with Douglas-Kroll-Hess (DKH) Hamiltonian to each ten sets of Ru and Os compounds. We perform the benchmark investigation of three density functionals (BP86, B3LYP and B2PLYP) using segmented all-electron relativistically contracted (SARC) basis set with the experimental Mössbauer isomer shifts for 99Ru and 189Os nuclides. Geometry optimizations at BP86 theory of level locate the structure in a local minimum. We calculate the contact density to the wavefunction obtained by a single point calculation. All functionals show the good linear correlation with experimental isomer shifts for both 99Ru and 189Os. Especially, B3LYP functional gives a stronger correlation compared to BP86 and B2PLYP functionals. The comparison of contact density between SARC and well-tempered basis set (WTBS) indicated that the numerical convergence of contact density cannot be obtained, but the reproducibility is less sensitive to the choice of basis set. We also estimate the values of Δ R/ R, which is an important nuclear constant, for 99Ru and 189Os nuclides by using the benchmark results. The sign of the calculated Δ R/ R values is consistent with the predicted data for 99Ru and 189Os. We obtain computationally the Δ R/ R values of 99Ru and 189Os (36.2 keV) as 2.35×10-4 and -0.20×10-4, respectively, at B3LYP level for SARC basis set.

  2. [The ethics of animal experimentation].

    PubMed

    Goffi, Jean-Yves

    2013-01-01

    The paper starts with a short definition of animal experimentation, then three main approaches to the practice are considered: unconditional approval (as advocated by Claude Bernard), conditional and restricted approval (as advocated by Peter Singer) and strict prohibition (as advocated by Tom Regan and Gary Francione). It is argued that what is actually approved or condemned in animal experimentation is the value of the scientific enterprise.

  3. A new experimental correlation for non-Newtonian behavior of COOH-DWCNTs/antifreeze nanofluid

    NASA Astrophysics Data System (ADS)

    Izadi, Farhad; Ranjbarzadeh, Ramin; Kalbasi, Rasool; Afrand, Masoud

    2018-04-01

    In this paper, the rheological behavior of nano-antifreeze consisting of 50%vol. water, 50%vol. ethylene glycol and different quantities of functionalized double walled carbon nanotubes has been investigated experimentally. Initially, nano-antifreeze samples were prepared with solid volume fractions of 0.05, 0.1, 0.2, 0.4, 0.6, 0.8 and 1% using two-step method. Then, the dynamic viscosity of the nano-antifreeze samples was measured at different shear rates and temperatures. At this stage, the results showed that base fluid had the Newtonian behavior, while the behavior of all nano-antifreeze samples was non-Newtonian. Since the behavior of the samples was similar to power law model, it was attempted to find the constants of this model including consistency index and power law index. Therefore, using the measured viscosity and shear rates, consistency index and power law index were obtained by curve-fitting method. The obtained values showed that consistency index amplified with increasing volume fraction, while reduced with enhancing temperature. Besides, the obtained values for power law index were less than 1 for all samples which means shear thinning behavior. Lastly, new correlations were suggested to estimate the consistency index and power law index using curve-fitting.

  4. Macroscopic analysis of gas-jet wiping: Numerical simulation and experimental approach

    NASA Astrophysics Data System (ADS)

    Lacanette, Delphine; Gosset, Anne; Vincent, Stéphane; Buchlin, Jean-Marie; Arquis, Éric

    2006-04-01

    Coating techniques are frequently used in industrial processes such as paper manufacturing, wire sleeving, and in the iron and steel industry. Depending on the application considered, the thickness of the resulting substrate is controlled by mechanical (scraper), electromagnetic (if the entrained fluid is appropriated), or hydrodynamic (gas-jet wiping) operations. This paper deals with the latter process, referred to as gas-jet wiping, in which a turbulent slot jet is used to wipe the coating film dragged by a moving substrate. This mechanism relies on the gas-jet-liquid film interaction taking place on the moving surface. The aim of this study is to compare the results obtained by a lubrication one-dimensional model, numerical volume of fluid-large eddy simulation (VOF-LES) modeling and an experimental approach. The investigation emphasizes the effect of the controlling wiping parameters, i.e., the pressure gradient and shear stress distributions induced by the jet, on the shape of the liquid film. Those profiles obtained experimentally and numerically for a jet impinging on a dry fixed surface are compared. The effect of the substrate motion and the presence of the dragged liquid film on these actuators are analyzed through numerical simulations. Good agreement is found between the film thickness profile in the wiping zone obtained from the VOF-LES simulations and with the analytical model, provided that a good model for the wiping actuators is used. The effect of the gas-jet nozzle to substrate standoff distance on the final coating thickness is analyzed; the experimental and predicted values are compared for a wide set of conditions. Finally, the occurrence of the splashing phenomenon, which is characterized by the ejection of droplets from the runback film flow at jet impingement, thus limiting the wiping process, is investigated through experiments and numerical simulations.

  5. An Experimental Investigation To Determine Interaction Between Rotating Bodies

    NASA Technical Reports Server (NTRS)

    Grugel, R. N.; Volz, M. P.; Mazuruk, K.

    2003-01-01

    A brass (copper+zinc) wheel, with a 4-in diameter and 1.4 in thick, was used for this investigation. Ceramic ball bearings were used to safely spin the wheel up to 40,000 rpm. The wheel was also electrically insulated from the rest of the armature. For spinning, an air turbine was used. The rotational velocity was measured by two methods: (1) A simple strobe light and (2) a photodiode that detected laser beam pulses as they passed through a slot in the rotating shaft. The magnetic sensor is based on a giant magnetoresistivity, and consists of a balanced bridge circuitry. The position of the sensor was as close as possible to the rim of the wheel. The linear dimension of the sensor is approximately equal to 8 mm so that the offset from the surface is on the order of 15 percent. We did not use any goniometer system, so the accuracy of the angular position is not high, being estimated within a few degrees, with the main uncertainty being the direction of Earth's magnetic field. We attempted to fit the experimental data with the presented theory by selecting the best value for the electrical conductivity of the wheel. The results of this procedure are displayed, where the black dots represent experimental values. A slight misfit on the right shoulder can be due to slight angular misalignment from a 90 degree position. The obtained value for the resistivity is 43 n(OMEGA)m, which compares well with those listed. We can conclude, based on these measurements, that the proposed theory satisfactorily explains our experiments.

  6. Missing-value estimation using linear and non-linear regression with Bayesian gene selection.

    PubMed

    Zhou, Xiaobo; Wang, Xiaodong; Dougherty, Edward R

    2003-11-22

    Data from microarray experiments are usually in the form of large matrices of expression levels of genes under different experimental conditions. Owing to various reasons, there are frequently missing values. Estimating these missing values is important because they affect downstream analysis, such as clustering, classification and network design. Several methods of missing-value estimation are in use. The problem has two parts: (1) selection of genes for estimation and (2) design of an estimation rule. We propose Bayesian variable selection to obtain genes to be used for estimation, and employ both linear and nonlinear regression for the estimation rule itself. Fast implementation issues for these methods are discussed, including the use of QR decomposition for parameter estimation. The proposed methods are tested on data sets arising from hereditary breast cancer and small round blue-cell tumors. The results compare very favorably with currently used methods based on the normalized root-mean-square error. The appendix is available from http://gspsnap.tamu.edu/gspweb/zxb/missing_zxb/ (user: gspweb; passwd: gsplab).

  7. Hydrostatic paradox: experimental verification of pressure equilibrium

    NASA Astrophysics Data System (ADS)

    Kodejška, Č.; Ganci, S.; Říha, J.; Sedláčková, H.

    2017-11-01

    This work is focused on the experimental verification of the balance between the atmospheric pressure acting on the sheet of paper, which encloses the cylinder completely or partially filled with water from below, where the hydrostatic pressure of the water column acts against the atmospheric pressure. First of all this paper solves a theoretical analysis of the problem, which is based, firstly, on the equation for isothermal process and, secondly, on the equality of pressures inside and outside the cylinder. From the measured values the confirmation of the theoretical quadratic dependence of the air pressure inside the cylinder on the level of the liquid in the cylinder is obtained, the maximum change in the volume of air within the cylinder occurs for the height of the water column L of one half of the total height of the vessel H. The measurements were made for different diameters of the cylinder and with plates made of different materials located at the bottom of the cylinder to prevent liquid from flowing out of the cylinder. The measured values were subjected to statistical analysis, which demonstrated the validity of the zero hypothesis, i.e. that the measured values are not statistically significantly different from the theoretically calculated ones at the statistical significance level α  =  0.05.

  8. Airglow during ionospheric modifications by the sura facility radiation. experimental results obtained in 2010

    NASA Astrophysics Data System (ADS)

    Grach, S. M.; Klimenko, V. V.; Shindin, A. V.; Nasyrov, I. A.; Sergeev, E. N.; A. Yashnov, V.; A. Pogorelko, N.

    2012-06-01

    We present the results of studying the structure and dynamics of the HF-heated volume above the Sura facility obtained in 2010 by measurements of ionospheric airglow in the red (λ = 630 nm) and green (λ = 557.7 nm) lines of atomic oxygen. Vertical sounding of the ionosphere (followed by modeling of the pump-wave propagation) and measurements of stimulated electromagnetic emission were used for additional diagnostics of ionospheric parameters and the processes occurring in the heated volume.

  9. Patterns of Wildlife Value Orientations

    Treesearch

    Harry C. Zinn; Michael J. Manfredo; Susan C. Barro

    2002-01-01

    Public value orientations toward wildlife may be growing less utilitarian and more protectionist. To better understand one aspect of this trend, we investigated patterns of wildlife value orientations within families. Using a mail survey, we sampled Pennsylvania and Colorado hunting license holders 50 or older; obtaining a 54% response rate (n = 599). Males (94% of...

  10. Incidence of Artifacts and Deviating Values in Research Data Obtained from an Anesthesia Information Management System in Children.

    PubMed

    Hoorweg, Anne-Lee J; Pasma, Wietze; van Wolfswinkel, Leo; de Graaff, Jurgen C

    2018-02-01

    Vital parameter data collected in anesthesia information management systems are often used for clinical research. The validity of this type of research is dependent on the number of artifacts. In this prospective observational cohort study, the incidence of artifacts in anesthesia information management system data was investigated in children undergoing anesthesia for noncardiac procedures. Secondary outcomes included the incidence of artifacts among deviating and nondeviating values, among the anesthesia phases, and among different anesthetic techniques. We included 136 anesthetics representing 10,236 min of anesthesia time. The incidence of artifacts was 0.5% for heart rate (95% CI: 0.4 to 0.7%), 1.3% for oxygen saturation (1.1 to 1.5%), 7.5% for end-tidal carbon dioxide (6.9 to 8.0%), 5.0% for noninvasive blood pressure (4.0 to 6.0%), and 7.3% for invasive blood pressure (5.9 to 8.8%). The incidence of artifacts among deviating values was 3.1% for heart rate (2.1 to 4.4%), 10.8% for oxygen saturation (7.6 to 14.8%), 14.1% for end-tidal carbon dioxide (13.0 to 15.2%), 14.4% for noninvasive blood pressure (10.3 to 19.4%), and 38.4% for invasive blood pressure (30.3 to 47.1%). Not all values in anesthesia information management systems are valid. The incidence of artifacts stored in the present pediatric anesthesia practice was low for heart rate and oxygen saturation, whereas noninvasive and invasive blood pressure and end-tidal carbon dioxide had higher artifact incidences. Deviating values are more often artifacts than values in a normal range, and artifacts are associated with the phase of anesthesia and anesthetic technique. Development of (automatic) data validation systems or solutions to deal with artifacts in data is warranted.

  11. Materialistic Values and Goals.

    PubMed

    Kasser, Tim

    2016-01-01

    Materialism comprises a set of values and goals focused on wealth, possessions, image, and status. These aims are a fundamental aspect of the human value/goal system, standing in relative conflict with aims concerning the well-being of others, as well as one's own personal and spiritual growth. Substantial evidence shows that people who place a relatively high priority on materialistic values/goals consume more products and incur more debt, have lower-quality interpersonal relationships, act in more ecologically destructive ways, have adverse work and educational motivation, and report lower personal and physical well-being. Experimentally activating materialistic aims causes similar outcomes. Given these ills, researchers have investigated means of decreasing people's materialism. Successful interventions encourage intrinsic/self-transcendent values/goals, increase felt personal security, and/or block materialistic messages from the environment. These interventions would likely be more effective if policies were also adopted that diminished contemporary culture's focus on consumption, profit, and economic growth.

  12. Recommended Values of the Fundamental Physical Constants: A Status Report

    PubMed Central

    Taylor, Barry N.; Cohen, E. Richard

    1990-01-01

    We summarize the principal advances made in the fundamental physical constants field since the completion of the 1986 CODATA least-squares adjustment of the constants and discuss their implications for both the 1986 set of recommended values and the next least-squares adjustment. In general, the new results lead to values of the constants with uncertainties 5 to 7 times smaller than the uncertainties assigned the 1986 values. However, the changes in the values themselves are less than twice the 1986 assigned one-standard-deviation uncertainties and thus are not highly significant. Although much new data has become available since 1986, three new results dominate the analysis: a value of the Planck constant obtained from a realization of the watt; a value of the fine-structure constant obtained from the magnetic moment anomaly of the electron; and a value of the molar gas constant obtained from the speed of sound in argon. Because of their dominant role in determining the values and uncertainties of many of the constants, it is highly desirable that additional results of comparable uncertainty that corroborate these three data items be obtained before the next adjustment is carried out. Until then, the 1986 CODATA set of recommended values will remain the set of choice. PMID:28179787

  13. An experimental investigation of convective heat transfer at evaporation of kerosene and water in the closed volume

    NASA Astrophysics Data System (ADS)

    Trushlyakov, V. I.; Lesnyak, I. Y.; Galfetti, L.

    2017-09-01

    An evaporation of kerosene and water was investigated based on convective heat transfer in the experimental setup simulating a typical volume of the fuel tank of the launch vehicle. Basic criteria of similarity used in choosing the design parameters of the setup, parameters of the coolant and model liquids, were numbers of Reynolds, Prandtl, Biot, and Nusselt. The used coolants were gases, including air and nitrogen; in addition, at the stage of preliminary experiments, products of combustion of hydroxyl-terminated polybutadiene (HTPB) were considered. Boundary conditions were taken for the liquid located on the plate in the form of "drop" and at its uniform film spread in the experimental model setup. On the basis of experimental investigations, the temperature values were obtained for the system "gas-liquid-wall", and areas of mass transfer surface and heat transfer coefficients of "gas-liquid" and "gas-plate" were determined for coolants (air and nitrogen) and for liquids (water and kerosene). The comparative analysis of the obtained results and the known data was carried out. Proposals for experiments using coolants based on HTPB combustion products have been formulated.

  14. Acoustic experimental investigation of interaction femtosecond laser pulses with gas-aerosol media and biological tissues

    NASA Astrophysics Data System (ADS)

    Bochkarev, N. N.; Kabanov, A. M.; Stepanov, A. N.

    2008-02-01

    Using two optical acoustic approaches we experimentally investigated spatial location of filament zone of propagation channel of focused laser radiation. For femtosecond pulses passing in air it was shown that nonlinear focus length had spatial scale of 1/P at initial power P moderate for self-focusing and at optical system focus distance significantly lower than Rayleigh beam length. The results of experimental optical acoustic investigation of femto- and nanosecond pulses attenuation by some biological tissues (muscular tissue, adipose tissue, cutaneous covering, milk) and optical breakdown thresholds on these one are presented. It was shown that penetration depth of short laser pulse radiation into biological tissues is the same as for longer one. However, amplitude of acoustic response to a process of interaction of femtosecond laser pulse with biological tissue is larger in several times than that to interaction with nanosecond pulses of the same power and spectral distribution. The obtained of threshold values can be interesting for tabulation of limit allowable levels of irradiation at work with laser radiation. Such values are unknown for femtosecond laser pulses today.

  15. Analysis of short pulse laser altimetry data obtained over horizontal path

    NASA Technical Reports Server (NTRS)

    Im, K. E.; Tsai, B. M.; Gardner, C. S.

    1983-01-01

    Recent pulsed measurements of atmospheric delay obtained by ranging to the more realistic targets including a simulated ocean target and an extended plate target are discussed. These measurements are used to estimate the expected timing accuracy of a correlation receiver system. The experimental work was conducted using a pulsed two color laser altimeter.

  16. A new mathematical approach for the estimation of the AUC and its variability under different experimental designs in preclinical studies.

    PubMed

    Navarro-Fontestad, Carmen; González-Álvarez, Isabel; Fernández-Teruel, Carlos; Bermejo, Marival; Casabó, Vicente Germán

    2012-01-01

    The aim of the present work was to develop a new mathematical method for estimating the area under the curve (AUC) and its variability that could be applied in different preclinical experimental designs and amenable to be implemented in standard calculation worksheets. In order to assess the usefulness of the new approach, different experimental scenarios were studied and the results were compared with those obtained with commonly used software: WinNonlin® and Phoenix WinNonlin®. The results do not show statistical differences among the AUC values obtained by both procedures, but the new method appears to be a better estimator of the AUC standard error, measured as the coverage of 95% confidence interval. In this way, the new proposed method demonstrates to be as useful as WinNonlin® software when it was applicable. Copyright © 2011 John Wiley & Sons, Ltd.

  17. Experimental Investigation of Thermal Properties in Glass Fiber Reinforced with Aluminium

    NASA Astrophysics Data System (ADS)

    Irudaya raja, S. Joseph; Vinod Kumar, T.; Sridhar, R.; Vivek, P.

    2017-03-01

    A test method of a Guarded heat flow meter are used to measure the thermal conductivity of glass fiber and filled with a aluminum powder epoxy composites using an instrument in accordance with ASTM. This experimental study reveals that the incorporation of aluminum and glass fiber reinforced results in enhancement of thermal conductivity of epoxy resin and thereby improves its heat transfer capability. Fiber metal laminates are good candidates for advanced automobile structural applications due to their high categorical mechanical and thermal properties. The most consequential factor in manufacturing of these laminates is the adhesive bonding between aluminum and FRP layers. Here several glass-fiber reinforced aluminum were laminates with different proportion of bonding adhesion were been manufactured. It was observed that the damage size is more preponderant in laminates with poor interfacial adhesion compared to that of laminates with vigorous adhesion between aluminum and glass layers numerically calculated ones and it is found that the values obtained for various composite models using experimental testing method.

  18. HARNESSING VALUES TO PROMOTE MOTIVATION IN EDUCATION

    PubMed Central

    Harackiewicz, Judith M.; Tibbetts, Yoi; Canning, Elizabeth; Hyde, Janet S.

    2017-01-01

    Purpose We review the interventions that promote motivation in academic contexts, with a focus on two primary questions: How can we motivate students to take more STEM courses? Once in those STEM courses, how can we keep students motivated and promote their academic achievement? Design/methodology/approach We have approached these two motivational questions from several perspectives, examining the theoretical issues with basic laboratory research, conducting longitudinal questionnaire studies in classrooms, and developing interventions implemented in different STEM contexts. Our research is grounded in three theories that we believe are complementary: expectancy-value theory (Eccles & Wigfield, 2002), interest theory (Hidi & Renninger, 2006), and self-affirmation theory (Steele, 1988). As social psychologists, we have focused on motivational theory and used experimental methods, with an emphasis on values – students’ perceptions of the value of academic tasks and students’ personal values that shape their experiences in academic contexts. Findings We review the experimental field studies in high-school science and college psychology classes, in which utility-value interventions promoted interest and performance for high-school students in science classes and for undergraduate students in psychology courses. We also review a randomized intervention in which parents received information about the utility value of math and science for their teens in high school; this intervention led students to take nearly one semester more of science and mathematics, compared with the control group. Finally, we review an experimental study of values affirmation in a college biology course and found that the intervention improved performance and retention for first-generation college students, closing the social-class achievement gap by 50%. We conclude by discussing the mechanisms through which these interventions work. Originality/value These interventions are exciting for

  19. Experimental feasibility of multistatic holography for breast microwave radar image reconstruction.

    PubMed

    Flores-Tapia, Daniel; Rodriguez, Diego; Solis, Mario; Kopotun, Nikita; Latif, Saeed; Maizlish, Oleksandr; Fu, Lei; Gui, Yonsheng; Hu, Can-Ming; Pistorius, Stephen

    2016-08-01

    The goal of this study was to assess the experimental feasibility of circular multistatic holography, a novel breast microwave radar reconstruction approach, using experimental datasets recorded using a preclinical experimental setup. The performance of this approach was quantitatively evaluated by calculating the signal to clutter ratio (SCR), contrast to clutter ratio (CCR), tumor to fibroglandular response ratio (TFRR), spatial accuracy, and reconstruction time. Five datasets were recorded using synthetic phantoms with the dielectric properties of breast tissue in the 1-6 GHz range using a custom radar system developed by the authors. The datasets contained synthetic structures that mimic the dielectric properties of fibroglandular breast tissues. Four of these datasets the authors covered an 8 mm inclusion that emulated a tumor. A custom microwave radar system developed at the University of Manitoba was used to record the radar responses from the phantoms. The datasets were reconstructed using the proposed multistatic approach as well as with a monostatic holography approach that has been previously shown to yield the images with the highest contrast and focal quality. For all reconstructions, the location of the synthetic tumors in the experimental setup was consistent with the position in the both the monostatic and multistatic reconstructed images. The average spatial error was less than 4 mm, which is half the spatial resolution of the data acquisition system. The average SCR, CCR, and TFRR of the images reconstructed with the multistatic approach were 15.0, 9.4, and 10.0 dB, respectively. In comparison, monostatic images obtained using the datasets from the same experimental setups yielded average SCR, CCR, and TFRR values of 12.8, 4.9, and 5.9 dB. No artifacts, defined as responses generated by the reconstruction method of at least half the energy of the tumor signatures, were noted in the multistatic reconstructions. The average execution time of the

  20. The essential value of long-term experimental data for hydrology and water management

    NASA Astrophysics Data System (ADS)

    Tetzlaff, D.; Carey, S. K.; McNamara, J. P.; Laudon, H.; Soulsby, C.

    2017-12-01

    Observations and data from long-term experimental watersheds are the foundation of hydrology as a geoscience. They allow us to benchmark process understanding, observe trends and natural cycles, and are pre-requisites for testing predictive models. Long-term experimental watersheds also are places where new measurement technologies are developed. These studies offer a crucial evidence base for understanding and managing the provision of clean water supplies; predicting and mitigating the effects of floods, and protecting ecosystem services provided by rivers and wetlands. They also show how to manage land and water in an integrated, sustainable way that reduces environmental and economic costs. We present a number of compelling examples illustrating how hydrologic process understanding has been generated through comparing hypotheses to data, and how this understanding has been essential for managing water supplies, floods, and ecosystem services today.

  1. Improving implementation of evidence-based practice in mental health service delivery: protocol for a cluster randomised quasi-experimental investigation of staff-focused values interventions

    PubMed Central

    2013-01-01

    Background There is growing acceptance that optimal service provision for individuals with severe and recurrent mental illness requires a complementary focus on medical recovery (i.e., symptom management and general functioning) and personal recovery (i.e., having a ‘life worth living’). Despite significant research attention and policy-level support, the translation of this vision of healthcare into changed workplace practice continues to elude. Over the past decade, evidence-based training interventions that seek to enhance the knowledge, attitudes, and skills of staff working in the mental health field have been implemented as a primary redress strategy. However, a large body of multi-disciplinary research indicates disappointing rates of training transfer. There is an absence of empirical research that investigates the importance of worker-motivation in the uptake of desired workplace change initiatives. ‘Autonomy’ is acknowledged as important to human effectiveness and as a correlate of workplace variables like productivity, and wellbeing. To our knowledge, there have been no studies that investigate purposeful and structured use of values-based interventions to facilitate increased autonomy as a means of promoting enhanced implementation of workplace change. Methods This study involves 200 mental health workers across 22 worksites within five community-managed organisations in three Australian states. It involves cluster-randomisation of participants within organisation, by work site, to the experimental (values) condition, or the control (implementation). Both conditions receive two days of training focusing on an evidence-based framework of mental health service delivery. The experimental group receives a third day of values-focused intervention and 12 months of values-focused coaching. Well-validated self-report measures are used to explore variables related to values concordance, autonomy, and self-reported implementation success. Audits of work

  2. Experimental Study of Residual Stresses in Metal Parts Obtained by Selective Laser Melting

    NASA Astrophysics Data System (ADS)

    Protasov, C. E.; Safronov, V. A.; Kotoban, D. V.; Gusarov, A. V.

    High local temperature gradients occur at additive manufacturing by selective laser melting of powder. This gives rise to undesirable residual stresses, deformations, and cracks. To understand how to control the formation of the residual stresses, a reliable method is necessary for measuring their distribution in the fabricated part. It is proposed to cut the part into thin plates and to reconstruct the residual stresses from the measured deformation of the plates. This method is tested on beams with square cross-section built from stainless steel. The beams were cut by electrical discharge machining and chemically etched. The obtained stress profile in vertical transversal direction slightly increases from the top to the bottom of the beam. This dependency is confirmed by numerical modeling. The measured stress profile agrees with the known results by other authors.

  3. Probabilities and statistics for backscatter estimates obtained by a scatterometer with applications to new scatterometer design data

    NASA Technical Reports Server (NTRS)

    Pierson, Willard J., Jr.

    1989-01-01

    The values of the Normalized Radar Backscattering Cross Section (NRCS), sigma (o), obtained by a scatterometer are random variables whose variance is a known function of the expected value. The probability density function can be obtained from the normal distribution. Models for the expected value obtain it as a function of the properties of the waves on the ocean and the winds that generated the waves. Point estimates of the expected value were found from various statistics given the parameters that define the probability density function for each value. Random intervals were derived with a preassigned probability of containing that value. A statistical test to determine whether or not successive values of sigma (o) are truly independent was derived. The maximum likelihood estimates for wind speed and direction were found, given a model for backscatter as a function of the properties of the waves on the ocean. These estimates are biased as a result of the terms in the equation that involve natural logarithms, and calculations of the point estimates of the maximum likelihood values are used to show that the contributions of the logarithmic terms are negligible and that the terms can be omitted.

  4. Validations of calibration-free measurements of electron temperature using double-pass Thomson scattering diagnostics from theoretical and experimental aspects.

    PubMed

    Tojo, H; Yamada, I; Yasuhara, R; Ejiri, A; Hiratsuka, J; Togashi, H; Yatsuka, E; Hatae, T; Funaba, H; Hayashi, H; Takase, Y; Itami, K

    2016-09-01

    This paper evaluates the accuracy of electron temperature measurements and relative transmissivities of double-pass Thomson scattering diagnostics. The electron temperature (T e ) is obtained from the ratio of signals from a double-pass scattering system, then relative transmissivities are calculated from the measured T e and intensity of the signals. How accurate the values are depends on the electron temperature (T e ) and scattering angle (θ), and therefore the accuracy of the values was evaluated experimentally using the Large Helical Device (LHD) and the Tokyo spherical tokamak-2 (TST-2). Analyzing the data from the TST-2 indicates that a high T e and a large scattering angle (θ) yield accurate values. Indeed, the errors for scattering angle θ = 135° are approximately half of those for θ = 115°. The method of determining the T e in a wide T e range spanning over two orders of magnitude (0.01-1.5 keV) was validated using the experimental results of the LHD and TST-2. A simple method to provide relative transmissivities, which include inputs from collection optics, vacuum window, optical fibers, and polychromators, is also presented. The relative errors were less than approximately 10%. Numerical simulations also indicate that the T e measurements are valid under harsh radiation conditions. This method to obtain T e can be considered for the design of Thomson scattering systems where there is high-performance plasma that generates harsh radiation environments.

  5. Estimating the impact of somatic cell count on the value of milk utilising parameters obtained from the published literature.

    PubMed

    Geary, Una; Lopez-Villalobos, Nicolas; O'Brien, Bernadette; Garrick, Dorian J; Shalloo, Laurence

    2014-05-01

    The impact of mastitis on milk value per litre independent of the effect of mastitis on milk volume, was quantified for Ireland using a meta-analysis and a processing sector model. Changes in raw milk composition, cheese processing and composition associated with increased bulk milk somatic cell count (BMSCC) were incorporated into the model. Processing costs and market values were representative of current industry values. It was assumed that as BMSCC increased (i) milk fat and milk protein increased and milk lactose decreased, (ii) fat and protein recoveries decreased, (iii) cheese protein decreased and cheese moisture increased. Five BMSCC categories were examined from ⩽100 000 to >400 000 cells/ml. The analysis showed that as BMSCC increased the production quantities reduced. An increase in BMSCC from 100 000 to >400 000 cells/ml saw a reduction in net revenue of 3·2% per annum (€51·3 million) which corresponded to a reduction in the value of raw milk of €0·0096 cents/l.

  6. [Value of liquid-based cytology of brushing specimens obtained via fiberoptic bronchoscopy for the diagnosis of lung cancer].

    PubMed

    Zhao, Huan; Guo, Huiqin; Zhang, Chuanxin; Zhao, Linlin; Cao, Jian; Pan, Qinjing

    2015-06-01

    To investigate the value of the liquid-based cytology (LBC) of brushing specimens obtained via fiberoptic bronchoscopy for clinical diagnosis of lung cancer. We retrospectively analyzed the LBC cases in our hospital from January 2011 to May 2012, and evaluate its role in the diagnosis of lung cancer. The clinical data of a total of 4 380 cases were reviewed and 3 763 of them had histopathological or clinical follow-up results (including 3 306 lung cancer cases and 457 benign lesion cases). The sensitivity, specificity, and accuracy of LBC diagnosis for lung cancer were 72.4% (2 392/3 306), 99.3% (454/457) and 75.6% (2 846/3 763), respectively. Of the 1 992 lung cancer cases diagnosed by brushing LBC, 528 cases (26.5%) were failed to take forceps biopsy and 113 cases (5.7%) showed negative forceps biopsy results. The accurate rate of subtyping of LBC for non-small cell carcinoma and small cell carcinoma was 99.0% (1 487/1 502) (P < 0.001). Take the resection histopathology as gold standard, the accurate rates of subtyping squamous cell carcinoma, adenocarcinoma and small cell carcinoma by LBC were 95.6% (351/367), 95.6% (351/367) and 100% (367/367), respectively, (P < 0.001). The accurate rates of subtyping of squamous cell carcinoma, adenocarcinoma and small cell carcinoma by forceps biopsy were 97.0% (293/302), 97.4% (294/302) and 99.7% (301/302), respectively, (Kappa = 0.895, P < 0.001). There was no significant difference in subtyping respectively between forceps biopsy and brushing LBC (P > 0.05). Fiberoptic bronchoscopic brushing liquid-based cytology can significantly improve the detection rate of lung cancer, and have a high specificity and accurate rate of subtyping. It is an effective tool for the diagnosis and subtyping of lung cancer.

  7. Experimental and DFT studies of (E)-2-[2-(2,6-dichlorophenyl)ethenyl]-8-hydroxyquinoline: electronic and vibrational properties.

    PubMed

    Sun, Wenqi; Yuan, Guozan; Liu, Jingxin; Ma, Li; Liu, Chengbu

    2013-04-01

    The title molecule (E)-2-[2-(2,6-dichlorophenyl)ethenyl]-8-hydroxyquinoline (DPEQ) was synthesized and characterized by FT-IR, UV-vis, NMR spectroscopy. The molecular geometry, vibrational frequencies and gauge independent atomic orbital (GIAO) 1H and 13C NMR chemical shift values of the compound in the ground state have been calculated by using the density functional theory (DFT) method. All the assignments of the theoretical frequencies were performed by potential energy distributions using VEDA 4 program. The calculated results indicate that the theoretical vibrational frequencies, 1H and 13C NMR chemical shift values show good agreement with experimental data. The electronic properties like UV-vis spectral analysis and HOMO-LUMO analysis of DPEQ have been reported and compared with experimental data. Information about the size, shape, charge density distribution and site of chemical reactivity of the molecule has been obtained by mapping electron density isosurface with molecular electrostatic potential (MEP). Copyright © 2013 Elsevier B.V. All rights reserved.

  8. Experimental and DFT studies of (E)-2-[2-(2,6-dichlorophenyl)ethenyl]-8-hydroxyquinoline: Electronic and vibrational properties

    NASA Astrophysics Data System (ADS)

    Sun, Wenqi; Yuan, Guozan; Liu, Jingxin; Ma, Li; Liu, Chengbu

    2013-04-01

    The title molecule (E)-2-[2-(2,6-dichlorophenyl)ethenyl]-8-hydroxyquinoline (DPEQ) was synthesized and characterized by FT-IR, UV-vis, NMR spectroscopy. The molecular geometry, vibrational frequencies and gauge independent atomic orbital (GIAO) 1H and 13C NMR chemical shift values of the compound in the ground state have been calculated by using the density functional theory (DFT) method. All the assignments of the theoretical frequencies were performed by potential energy distributions using VEDA 4 program. The calculated results indicate that the theoretical vibrational frequencies, 1H and 13C NMR chemical shift values show good agreement with experimental data. The electronic properties like UV-vis spectral analysis and HOMO-LUMO analysis of DPEQ have been reported and compared with experimental data. Information about the size, shape, charge density distribution and site of chemical reactivity of the molecule has been obtained by mapping electron density isosurface with molecular electrostatic potential (MEP).

  9. Experimental determination of pCo perturbation factors for plane-parallel chambers

    NASA Astrophysics Data System (ADS)

    Kapsch, R. P.; Bruggmoser, G.; Christ, G.; Dohm, O. S.; Hartmann, G. H.; Schüle, E.

    2007-12-01

    For plane-parallel chambers used in electron dosimetry, modern dosimetry protocols recommend a cross-calibration against a calibrated cylindrical chamber. The rationale for this is the unacceptably large (up to 3-4%) chamber-to-chamber variations of the perturbation factors (pwall)Co, which have been reported for plane-parallel chambers of a given type. In some recent publications, it was shown that this is no longer the case for modern plane-parallel chambers. The aims of the present study are to obtain reliable information about the variation of the perturbation factors for modern types of plane-parallel chambers, and—if this variation is found to be acceptably small—to determine type-specific mean values for these perturbation factors which can be used for absorbed dose measurements in electron beams using plane-parallel chambers. In an extensive multi-center study, the individual perturbation factors pCo (which are usually assumed to be equal to (pwall)Co) for a total of 35 plane-parallel chambers of the Roos type, 15 chambers of the Markus type and 12 chambers of the Advanced Markus type were determined. From a total of 188 cross-calibration measurements, variations of the pCo values for different chambers of the same type of at most 1.0%, 0.9% and 0.6% were found for the chambers of the Roos, Markus and Advanced Markus types, respectively. The mean pCo values obtained from all measurements are \\bar{p}^Roos_Co = 1.0198, \\bar{p}^Markus_Co = 1.0175 and \\bar{p}^Advanced_Co = 1.0155 ; the relative experimental standard deviation of the individual pCo values is less than 0.24% for all chamber types; the relative standard uncertainty of the mean pCo values is 1.1%.

  10. Pre-Licensed Nursing Students Rate Professional Values

    ERIC Educational Resources Information Center

    Garee, Denise L.

    2016-01-01

    Ethical decision making of new nurses relies on professional values and moral development obtained during training. This descriptive, comparative study demonstrated the importance values attributed to the items of the Nurses' Professional Values Scale-Revised (Weis & Schank, 2009), by a sample of senior ADN and BSN students from across the…

  11. Bartlett Experimental Forest

    Treesearch

    Jane Gamal-Eldin

    1998-01-01

    The Bartlett Experimental Forest is a field laboratory for research on the ecology and management of northern forest ecosystems. Research on the Bartlett includes: 1) extensive investigations on structure and dynamics of forests at several levels, and developing management alternatives to reflect an array of values and benefits sought by users of forest lands, 2) a...

  12. Using the Viking biology experimental results to obtain chemical information about Martian regolith

    NASA Technical Reports Server (NTRS)

    Plumb, Robert C.

    1992-01-01

    Although initially formulated as biology experiments, most of the results produced by the Viking Labeled Release (LR), Gas Exchange (GEX), and Pyrolytic Release (PR) experiments have been reproduced by chemical means. The experiments do not need more study as 'biological' phenomena, but they do deserve much more careful consideration from a chemical viewpoint. They are the only 'wet-chemical' experiments that scientists have performed on another planet, but they have not found very general use as sources of scientific information. There is a large set of potentially useful chemical observations, e.g., the three resolvable and precisely measured kinetic components of the release of C-14-labeled gases, the thermal sensitivity and magnitudes of the oxidation reaction(s) of the LR experiments, the kinetics and magnitude of the O2 and CO2 release of the GEX experiments, the thermal sensitivity of the GEX results, the differences between the thermal sensitivity of the GEX and the thermal sensitivity of the LR responses, and the kinetics and magnitudes of the LR successive injection reabsorption effect. It should be possible to test many chemical aspects of hypothetical martian phenomena in experiments using the biology experimental configurations and derive much valuable information by comparisons with the Viking observations.

  13. Experimental and theoretical study on the structure and vibrational spectra of β-2-aminopyridinium dihydrogenphosphate

    NASA Astrophysics Data System (ADS)

    Çırak, Çağrı; Demir, Selçuk; Ucun, Fatih; Çubuk, Osman

    2011-08-01

    Experimental and theoretical vibrational spectra of β-2-aminopyridinium dihydrogenphosphate (β-2APDP) have been investigated. The FT-IR spectrum of β-2APDP was recorded in the region 4000-400 cm -1. The optimized molecular structure and theoretical vibrational frequencies of β-2APDP have been investigated using ab initio Hartree-Fock (HF) and density functional B3LYP method with 6-311++G(d,p) basis set. The optimized geometric parameters (bond lengths and bond angles) and theoretical frequencies have been compared with the corresponding experimental data and it is found that they agree well with each other. All the assignments of the theoretical frequencies were performed by potential energy distributions using VEDA 4 program. Furthermore, the used scale factors were obtained from the ratio of the frequency values of the strongest peaks in the experimental and theoretical IR spectra. From the results it was concluded that the B3LYP method is superior to the HF method for the vibrational frequencies.

  14. Experimental Mapping and Benchmarking of Magnetic Field Codes on the LHD Ion Accelerator

    NASA Astrophysics Data System (ADS)

    Chitarin, G.; Agostinetti, P.; Gallo, A.; Marconato, N.; Nakano, H.; Serianni, G.; Takeiri, Y.; Tsumori, K.

    2011-09-01

    For the validation of the numerical models used for the design of the Neutral Beam Test Facility for ITER in Padua [1], an experimental benchmark against a full-size device has been sought. The LHD BL2 injector [2] has been chosen as a first benchmark, because the BL2 Negative Ion Source and Beam Accelerator are geometrically similar to SPIDER, even though BL2 does not include current bars and ferromagnetic materials. A comprehensive 3D magnetic field model of the LHD BL2 device has been developed based on the same assumptions used for SPIDER. In parallel, a detailed experimental magnetic map of the BL2 device has been obtained using a suitably designed 3D adjustable structure for the fine positioning of the magnetic sensors inside 27 of the 770 beamlet apertures. The calculated values have been compared to the experimental data. The work has confirmed the quality of the numerical model, and has also provided useful information on the magnetic non-uniformities due to the edge effects and to the tolerance on permanent magnet remanence.

  15. Bayesian analysis of experimental epidemics of foot-and-mouth disease.

    PubMed Central

    Streftaris, George; Gibson, Gavin J.

    2004-01-01

    We investigate the transmission dynamics of a certain type of foot-and-mouth disease (FMD) virus under experimental conditions. Previous analyses of experimental data from FMD outbreaks in non-homogeneously mixing populations of sheep have suggested a decline in viraemic level through serial passage of the virus, but these do not take into account possible variation in the length of the chain of viral transmission for each animal, which is implicit in the non-observed transmission process. We consider a susceptible-exposed-infectious-removed non-Markovian compartmental model for partially observed epidemic processes, and we employ powerful methodology (Markov chain Monte Carlo) for statistical inference, to address epidemiological issues under a Bayesian framework that accounts for all available information and associated uncertainty in a coherent approach. The analysis allows us to investigate the posterior distribution of the hidden transmission history of the epidemic, and thus to determine the effect of the length of the infection chain on the recorded viraemic levels, based on the posterior distribution of a p-value. Parameter estimates of the epidemiological characteristics of the disease are also obtained. The results reveal a possible decline in viraemia in one of the two experimental outbreaks. Our model also suggests that individual infectivity is related to the level of viraemia. PMID:15306359

  16. Comparative development of Taenia solium in experimental models.

    PubMed

    Maravilla, P; Avila, G; Cabrera, V; Aguilar, L; Flisser, A

    1998-10-01

    Various mammals were evaluated as experimental models of adult Taenia solium. Suppressed and nonsuppressed hosts were used as experimental models. Infections were performed per os with cysticerci obtained from pigs; immunosuppression was induced with methyl prednisolone acetate at intervals of 10-14 days after infection. Tapeworms developed in hamsters, gerbils, and chinchillas but failed to develop in rabbits, cats, pigs, and rhesus monkeys. In infectable animals, treatment with the steroid facilitated maintenance and development of the parasite, and more tapeworms were obtained. Mature and some pregravid proglottids were recovered from hamsters and gerbils, whereas a gravid T. solium was obtained from a chinchilla at 12 wk postinfection. Eggs recovered from the chinchilla transformed into cysticerci in a pig 12 wk after oral infection. The T. solium-chinchilla experimental system seems to be an alternative definitive host for this parasite and thus the basis for a great diversity of studies.

  17. 12 CFR 703.11 - Valuing securities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) At least monthly, a Federal credit union must determine the fair value of each security it holds. It may determine fair value by obtaining a price quotation on the security from an industry-recognized... supervisory committee or its external auditor must independently assess the reliability of monthly price...

  18. On the equivalence of experimental B(E2) values determined by various techniques

    DOE PAGES

    Birch, M.; Pritychenko, B.; Singh, B.

    2016-06-30

    In this paper, we establish the equivalence of the various techniques for measuring B(E2) values using a statistical analysis. Data used in this work come from the recent compilation by B. Pritychenko et al. (2016). We consider only those nuclei for which the B(E2) values were measured by at least two different methods, with each method being independently performed at least twice. Our results indicate that most prevalent methods of measuring B(E2) values are equivalent, with some weak evidence that Doppler-shift attenuation method (DSAM) measurements may differ from Coulomb excitation (CE) and nuclear resonance fluorescence (NRF) measurements. However, such anmore » evidence appears to arise from discrepant DSAM measurements of the lifetimes for 60Ni and some Sn nuclei rather than a systematic deviation in the method itself.« less

  19. Experimental analysis of tablet properties for discrete element modeling of an active coating process.

    PubMed

    Just, Sarah; Toschkoff, Gregor; Funke, Adrian; Djuric, Dejan; Scharrer, Georg; Khinast, Johannes; Knop, Klaus; Kleinebudde, Peter

    2013-03-01

    Coating of solid dosage forms is an important unit operation in the pharmaceutical industry. In recent years, numerical simulations of drug manufacturing processes have been gaining interest as process analytical technology tools. The discrete element method (DEM) in particular is suitable to model tablet-coating processes. For the development of accurate simulations, information on the material properties of the tablets is required. In this study, the mechanical parameters Young's modulus, coefficient of restitution (CoR), and coefficients of friction (CoF) of gastrointestinal therapeutic systems (GITS) and of active-coated GITS were measured experimentally. The dynamic angle of repose of these tablets in a drum coater was investigated to revise the CoF. The resulting values were used as input data in DEM simulations to compare simulation and experiment. A mean value of Young's modulus of 31.9 MPa was determined by the uniaxial compression test. The CoR was found to be 0.78. For both tablet-steel and tablet-tablet friction, active-coated GITS showed a higher CoF compared with GITS. According to the values of the dynamic angle of repose, the CoF was adjusted to obtain consistent tablet motion in the simulation and in the experiment. On the basis of this experimental characterization, mechanical parameters are integrated into DEM simulation programs to perform numerical analysis of coating processes.

  20. Experimental determination of the response functions of a Bonner sphere spectrometer to monoenergetic neutrons

    NASA Astrophysics Data System (ADS)

    Hu, Z.; Chen, Z.; Peng, X.; Du, T.; Cui, Z.; Ge, L.; Zhu, W.; Wang, Z.; Zhu, X.; Chen, J.; Zhang, G.; Li, X.; Chen, J.; Zhang, H.; Zhong, G.; Hu, L.; Wan, B.; Gorini, G.; Fan, T.

    2017-06-01

    A Bonner sphere spectrometer (BSS) plays an important role in characterizing neutron spectra and determining their neutron dose in a neutron-gamma mixed field. A BSS consisting of a set of nine polyethylene spheres with a 3He proportional counter was developed at Peking University to perform neutron spectrum and dosimetry measurements. Response functions (RFs) of the BSS were calculated with the general Monte Carlo code MCNP5 for the neutron energy range from thermal up to 20 MeV, and were experimentally calibrated with monoenergetic neutron beams from 144 keV to 14 MeV on a 4.5 MV Van de Graaff accelerator. The calculated RFs were corrected with the experimental values, and the whole response matrix was completely established. The spectrum of a 241Am-Be source was obtained after unfolding the measurement data of the BSS to the source and in fair agreement with the expected one. The integral ambient dose equivalent corresponding to the spectrum was 0.95 of the expected value. Results of the unfolded spectrum and the integral dose equivalent measured by the BSS verified that the RFs of the BSS were well established.

  1. Atomistic modeling and experimental studies of radiation damage in monazite-type LaPO4 ceramics

    NASA Astrophysics Data System (ADS)

    Ji, Yaqi; Kowalski, Piotr M.; Neumeier, Stefan; Deissmann, Guido; Kulriya, Pawan K.; Gale, Julian D.

    2017-02-01

    We simulated the threshold displacement energies (Ed), the related displacement and defect formation probabilities, and the energy barriers in LaPO4 monazite-type ceramics. The obtained Ed values for La, P, O primary knock-on atoms (PKA) are 56 eV, 75 eV and 8 eV, respectively. We found that these energies can be correlated with the energy barriers that separate the defect from the initial states. The Ed values are about twice the values of energy barriers, which is explained through an efficient dissipation of the PKA kinetic energy in the considered system. The computed Ed were used in simulations of the extent of radiation damage in La0.2Gd0.8PO4 solid solution, investigated experimentally. We found that this lanthanide phosphate fully amorphises in the ion beam experiments for fluences higher than ∼1013 ions/cm2.

  2. Effect of experimental and sample factors on dehydration kinetics of mildronate dihydrate: mechanism of dehydration and determination of kinetic parameters.

    PubMed

    Bērziņš, Agris; Actiņš, Andris

    2014-06-01

    The dehydration kinetics of mildronate dihydrate [3-(1,1,1-trimethylhydrazin-1-ium-2-yl)propionate dihydrate] was analyzed in isothermal and nonisothermal modes. The particle size, sample preparation and storage, sample weight, nitrogen flow rate, relative humidity, and sample history were varied in order to evaluate the effect of these factors and to more accurately interpret the data obtained from such analysis. It was determined that comparable kinetic parameters can be obtained in both isothermal and nonisothermal mode. However, dehydration activation energy values obtained in nonisothermal mode showed variation with conversion degree because of different rate-limiting step energy at higher temperature. Moreover, carrying out experiments in this mode required consideration of additional experimental complications. Our study of the different sample and experimental factor effect revealed information about changes of the dehydration rate-limiting step energy, variable contribution from different rate limiting steps, as well as clarified the dehydration mechanism. Procedures for convenient and fast determination of dehydration kinetic parameters were offered. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

  3. Efficacy of Group Based Learning in Learning Moral Value

    ERIC Educational Resources Information Center

    Singaravelu, G.

    2008-01-01

    The present study highlights the efficacy of Group Based Learning on cultivating moral value of the students at Standard VIII. Parallel group Experimental method was adopted in the study. Eighty students (control group = 40 students + experimental = 40 students) were selected as sample for the study. Researcher self-made achievement tool was…

  4. Experimental investigation of a packed bed thermal energy storage system

    NASA Astrophysics Data System (ADS)

    Cascetta, Mario; Cau, Giorgio; Puddu, Pierpaolo; Serra, Fabio

    2015-11-01

    In this work experimental investigations on a thermal energy storage system with a solid material as storage media and air as heat transfer fluid will be presented. The experimental test rig, installed at the DIMCM of the University of Cagliari, consists of a carbon steel tank filled with freely poured alumina beads that allows investigations of heat transfer phenomena in packed beds. The aim of this work is to show the influence of the operating conditions and physical parameters on thermocline formation and, in particular, the thermal behaviour of the thermal energy storage for repeated charging and discharging cycles. Better charging efficiency is obtained for lower values of mass flow rate and maximum air temperature and for increasing aspect ratio. A decreasing influence of the metal wall with continuous operation is also highlighted. In conclusion, the analysis focuses on the thermal hysteresis phenomenon, which causes degradation of the thermocline and the reduction of the energy that can be stored by the accumulator as the repeated number of cycles increases.

  5. Lunar tidal acceleration obtained from satellite-derived ocean tide parameters

    NASA Technical Reports Server (NTRS)

    Goad, C. C.; Douglas, B. C.

    1978-01-01

    One hundred sets of mean elements of GEOS-3 computed at 2-day intervals yielded observation equations for the M sub 2 ocean tide from the long periodic variations of the inclination and node of the orbit. The 2nd degree Love number was given the value k sub 2 = 0.30 and the solid tide phase angle was taken to be zero. Combining obtained equations with results for the satellite 1967-92A gives the M sub 2 ocean tide parameter values. Under the same assumption of zero solid tide phase lag, the lunar tidal acceleration was found mostly due to the C sub 22 term in the expansion of the M sub 2 tide with additional small contributions from the 0 sub 1 and N sub 2 tides. Using Lambeck's (1975) estimates for the latter, the obtained acceleration in lunar longitudal in excellent agreement with the most recent determinations from ancient and modern astronomical data.

  6. [Effect of home-processing in the preparation of pinto beans (Phaseolus vulgaris L.) on the tannin content and nutritive value of proteins].

    PubMed

    Goycoolea, F; González de Mejía, E; Barrón, J M; Valencia, M E

    1990-06-01

    A 3(2) factor design was carried out in order to investigate the different home-cooking treatments applied in the preparation of pinto beans (Phaseolus vulgaris L.) on the nutritive value of their protein. The factors studied were previous soaking, type of cooking and addition of cooking broth. Biological evaluation of the protein was performed, and the protein efficiency ratio (PER) and apparent digestibility of the protein (DAP) values were obtained. The tannin content was measured in hulls, cotyledons and in the cooking broths of each experimental treatment. The most significant effect of the PER value was the type of cooking (P less than 0.0001), followed by the addition of cooking broth (P less than 0.05) as well as a significant interaction between cooking method and addition of broth (P less than 0.025). Soaking did not have significant effects per se or through its interactions in relation to PER. The highest values for PER and DAP were obtained with the boiling treatment without broth. The detrimental effect of the cooking broth can be explained by its tannin content (108.5-272.25 mg Eq. catechin/100g).

  7. Comparison between maximum radial expansion of ultrasound contrast agents and experimental postexcitation signal results.

    PubMed

    King, Daniel A; O'Brien, William D

    2011-01-01

    Experimental postexcitation signal data of collapsing Definity microbubbles are compared with the Marmottant theoretical model for large amplitude oscillations of ultrasound contrast agents (UCAs). After taking into account the insonifying pulse characteristics and size distribution of the population of UCAs, a good comparison between simulated results and previously measured experimental data is obtained by determining a threshold maximum radial expansion (Rmax) to indicate the onset of postexcitation. This threshold Rmax is found to range from 3.4 to 8.0 times the initial bubble radius, R0, depending on insonification frequency. These values are well above the typical free bubble inertial cavitation threshold commonly chosen at 2R0. The close agreement between the experiment and models suggests that lipid-shelled UCAs behave as unshelled bubbles during most of a large amplitude cavitation cycle, as proposed in the Marmottant equation.

  8. alpha-decay half-lives and Q{sub a}lpha values of superheavy nuclei

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dong Jianmin; Graduate University of Chinese Academy of Sciences, Beijing 100049; School of Nuclear Science and Technology, Lanzhou University, Lanzhou 730000

    2010-06-15

    The alpha-decay half-lives of recently synthesized superheavy nuclei (SHN) are investigated by employing a unified fission model (UFM) where a new method to calculate the assault frequency of alpha emission is used. The excellent agreement with the experimental data indicates the UFM is a useful tool to investigate these alpha decays. It is found that the alpha-decay half-lives become more and more insensitive to the Q{sub a}lpha values as the atomic number increases on the whole, which is favorable for us to predict the half-lives of SHN. In addition, a formula is proposed to compute the Q{sub a}lpha values formore » the nuclei with Z>=92 and N>=140 with a good accuracy, according to which the long-lived SHN should be neutron rich. Several weeks ago, two isotopes of a new element with atomic number Z=117 were synthesized and their alpha-decay chains have been observed. The Q{sub a}lpha formula is found to work well for these nuclei, confirming its predictive power. The experimental half-lives are well reproduced by employing the UFM with the experimental Q{sub a}lpha values. This fact that the experimental half-lives are compatible with experimental Q{sub a}lpha values supports the synthesis of a new element 117 and the experimental measurements to a certain extent.« less

  9. HARNESSING VALUES TO PROMOTE MOTIVATION IN EDUCATION.

    PubMed

    Harackiewicz, Judith M; Tibbetts, Yoi; Canning, Elizabeth; Hyde, Janet S

    2014-01-01

    We review the interventions that promote motivation in academic contexts, with a focus on two primary questions: How can we motivate students to take more STEM courses? Once in those STEM courses, how can we keep students motivated and promote their academic achievement? We have approached these two motivational questions from several perspectives, examining the theoretical issues with basic laboratory research, conducting longitudinal questionnaire studies in classrooms, and developing interventions implemented in different STEM contexts. Our research is grounded in three theories that we believe are complementary: expectancy-value theory (Eccles & Wigfield, 2002), interest theory (Hidi & Renninger, 2006), and self-affirmation theory (Steele, 1988). As social psychologists, we have focused on motivational theory and used experimental methods, with an emphasis on values - students' perceptions of the value of academic tasks and students' personal values that shape their experiences in academic contexts. We review the experimental field studies in high-school science and college psychology classes, in which utility-value interventions promoted interest and performance for high-school students in science classes and for undergraduate students in psychology courses. We also review a randomized intervention in which parents received information about the utility value of math and science for their teens in high school; this intervention led students to take nearly one semester more of science and mathematics, compared with the control group. Finally, we review an experimental study of values affirmation in a college biology course and found that the intervention improved performance and retention for first-generation college students, closing the social-class achievement gap by 50%. We conclude by discussing the mechanisms through which these interventions work. These interventions are exciting for their broad applicability in improving students' academic choices and

  10. Obtaining of caffeine from Turkish tea fiber and stalk wastes.

    PubMed

    Gürü, M; Içen, H

    2004-08-01

    The aim of this study was to find a cheap method to obtain caffeine. Experiments were performed on fiber and stalk wastes of Turkish tea plants that had no economical value other than being used merely as low grade fuel and fodder. Tea stalks and fiber were obtained from tea factories. Parameters affecting caffeine extraction from tea wastes were determined to be, mixing rate, water/tea ratio, temperature, time and particle size. The maximum yields by dried mass from the tea fibers and stalks were 1.16% and 0.92%, respectively.

  11. Brief report: Into the wild? How a film can change adolescents' values.

    PubMed

    Döring, Anna K; Hillbrink, Alessa

    2015-04-01

    In adolescence, behavior and attitudes are constantly rethought and value priorities are established. Still, there is hardly any research addressing how values are shaped throughout this sensitive period. We employed an experimental design, testing whether adolescents' values can be influenced by exposure to a film. In our study, 154 German adolescents (80 females, ages 13-15) were randomly assigned to an experimental group that watched excerpts from the film "Into the wild" or to a control group. Value change was assessed in a pre-post-test design with a one-week interval. As hypothesized, values changed in the direction of those displayed by the film's protagonist: Universalism values increased significantly and conformity values decreased significantly as compared to the control group. Our findings suggest that single exposure to a film may initiate value change, indicating that not only major live events, but also everyday experiences significantly affect adolescents' values. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  12. Experimental damping-in-pitch of two slender cones at Mach 2 and incidences up to 30 deg

    NASA Technical Reports Server (NTRS)

    Iyenger, S.

    1972-01-01

    Oscillatory experiments were performed on two slender cones at Mach 2 and incidences up to 30 deg, using three different experimental arrangements. The damping-in-pitch was found to remain constant at incidences of up to a value approximately corresponding to the cone semi-angle, after which an almost linear increase with incidence was noted. The results obtained with the different techniques were in very good agreement up to an incidence of 15 deg and in some cases up to 25 deg.

  13. Experimental investigations of heat transfer and temperature fields in models simulating fuel assemblies used in the core of a nuclear reactor with a liquid heavy-metal coolant

    NASA Astrophysics Data System (ADS)

    Belyaev, I. A.; Genin, L. G.; Krylov, S. G.; Novikov, A. O.; Razuvanov, N. G.; Sviridov, V. G.

    2015-09-01

    The aim of this experimental investigation is to obtain information on the temperature fields and heat transfer coefficients during flow of liquid-metal coolant in models simulating an elementary cell in the core of a liquid heavy metal cooled fast-neutron reactor. Two design versions for spacing fuel rods in the reactor core were considered. In the first version, the fuel rods were spaced apart from one another using helical wire wound on the fuel rod external surface, and in the second version spacer grids were used for the same purpose. The experiments were carried out on the mercury loop available at the Moscow Power Engineering Institute National Research University's Chair of Engineering Thermal Physics. Two experimental sections simulating an elementary cell for each of the fuel rod spacing versions were fabricated. The temperature fields were investigated using a dedicated hinged probe that allows temperature to be measured at any point of the studied channel cross section. The heat-transfer coefficients were determined using the wall temperature values obtained at the moment when the probe thermocouple tail end touched the channel wall. Such method of determining the wall temperature makes it possible to alleviate errors that are unavoidable in case of measuring the wall temperature using thermocouples placed in slots milled in the wall. In carrying out the experiments, an automated system of scientific research was applied, which allows a large body of data to be obtained within a short period of time. The experimental investigations in the first test section were carried out at Re = 8700, and in the second one, at five values of Reynolds number. Information about temperature fields was obtained by statistically processing the array of sampled probe thermocouple indications at 300 points in the experimental channel cross section. Reach material has been obtained for verifying the codes used for calculating velocity and temperature fields in channels with

  14. Values of Catholic science educators: Their impact on attitudes of science teaching and learning

    NASA Astrophysics Data System (ADS)

    DeMizio, Joanne Greenwald

    This quantitative study examined the associations between the values held by middle school science teachers in Catholic schools and their attitudes towards science teaching. A total of six value types were studied---theoretical, economic, aesthetic, social, political, and religious. Teachers can have negative, positive, or neutral attitudes towards their teaching that are linked to their teaching practices and student learning. These teachers' attitudes may affect their competence and have a subsequent impact on their students' attitudes and dispositions towards science. Of particular interest was the relationship between science teaching attitudes and religious values. A non-experimental research design was used to obtain responses from 54 teachers with two survey instruments, the Science Teaching Attitude Scale II and the Allport-Vernon-Lindzey Study of Values. Stepwise multiple regression analysis showed that political values were negatively associated with attitudes towards science teaching. Data collected were inconsistent with the existence of any measurable association between religious values and attitudes towards science teaching. This study implies that science teacher preparation programs should adopt a more contextual perspective on science that seeks to develop the valuation of science within a cultural context, as well as programs that enable teachers to identify the influence of their beliefs on instructional actions to optimize the impact of learning new teaching practices that may enhance student learning.

  15. Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements

    PubMed Central

    Zhou, Rui; Maisuradze, Gia G.; Suñol, David; Todorovski, Toni; Macias, Maria J.; Xiao, Yi; Scheraga, Harold A.; Czaplewski, Cezary; Liwo, Adam

    2014-01-01

    To demonstrate the utility of the coarse-grained united-residue (UNRES) force field to compare experimental and computed kinetic data for folding proteins, we have performed long-time millisecond-timescale canonical Langevin molecular dynamics simulations of the triple β-strand from the Formin binding protein 28 WW domain and six nonnatural variants, using UNRES. The results have been compared with available experimental data in both a qualitative and a quantitative manner. Complexities of the folding pathways, which cannot be determined experimentally, were revealed. The folding mechanisms obtained from the simulated folding kinetics are in agreement with experimental results, with a few discrepancies for which we have accounted. The origins of single- and double-exponential kinetics and their correlations with two- and three-state folding scenarios are shown to be related to the relative barrier heights between the various states. The rate constants obtained from time profiles of the fractions of the native, intermediate, and unfolded structures, and the kinetic equations fitted to them, correlate with the experimental values; however, they are about three orders of magnitude larger than the experimental ones for most of the systems. These differences are in agreement with the timescale extension derived by scaling down the friction of water and averaging out the fast degrees of freedom when passing from all-atom to a coarse-grained representation. Our results indicate that the UNRES force field can provide accurate predictions of folding kinetics of these WW domains, often used as models for the study of the mechanisms of proein folding. PMID:25489078

  16. Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements.

    PubMed

    Zhou, Rui; Maisuradze, Gia G; Suñol, David; Todorovski, Toni; Macias, Maria J; Xiao, Yi; Scheraga, Harold A; Czaplewski, Cezary; Liwo, Adam

    2014-12-23

    To demonstrate the utility of the coarse-grained united-residue (UNRES) force field to compare experimental and computed kinetic data for folding proteins, we have performed long-time millisecond-timescale canonical Langevin molecular dynamics simulations of the triple β-strand from the Formin binding protein 28 WW domain and six nonnatural variants, using UNRES. The results have been compared with available experimental data in both a qualitative and a quantitative manner. Complexities of the folding pathways, which cannot be determined experimentally, were revealed. The folding mechanisms obtained from the simulated folding kinetics are in agreement with experimental results, with a few discrepancies for which we have accounted. The origins of single- and double-exponential kinetics and their correlations with two- and three-state folding scenarios are shown to be related to the relative barrier heights between the various states. The rate constants obtained from time profiles of the fractions of the native, intermediate, and unfolded structures, and the kinetic equations fitted to them, correlate with the experimental values; however, they are about three orders of magnitude larger than the experimental ones for most of the systems. These differences are in agreement with the timescale extension derived by scaling down the friction of water and averaging out the fast degrees of freedom when passing from all-atom to a coarse-grained representation. Our results indicate that the UNRES force field can provide accurate predictions of folding kinetics of these WW domains, often used as models for the study of the mechanisms of proein folding.

  17. Time-varying singular value decomposition for periodic transient identification in bearing fault diagnosis

    NASA Astrophysics Data System (ADS)

    Zhang, Shangbin; Lu, Siliang; He, Qingbo; Kong, Fanrang

    2016-09-01

    For rotating machines, the defective faults of bearings generally are represented as periodic transient impulses in acquired signals. The extraction of transient features from signals has been a key issue for fault diagnosis. However, the background noise reduces identification performance of periodic faults in practice. This paper proposes a time-varying singular value decomposition (TSVD) method to enhance the identification of periodic faults. The proposed method is inspired by the sliding window method. By applying singular value decomposition (SVD) to the signal under a sliding window, we can obtain a time-varying singular value matrix (TSVM). Each column in the TSVM is occupied by the singular values of the corresponding sliding window, and each row represents the intrinsic structure of the raw signal, namely time-singular-value-sequence (TSVS). Theoretical and experimental analyses show that the frequency of TSVS is exactly twice that of the corresponding intrinsic structure. Moreover, the signal-to-noise ratio (SNR) of TSVS is improved significantly in comparison with the raw signal. The proposed method takes advantages of the TSVS in noise suppression and feature extraction to enhance fault frequency for diagnosis. The effectiveness of the TSVD is verified by means of simulation studies and applications to diagnosis of bearing faults. Results indicate that the proposed method is superior to traditional methods for bearing fault diagnosis.

  18. Experimental approach to the anion problem in DFT calculation of the partial charge transfer during adsorption at electrochemical interfaces

    NASA Astrophysics Data System (ADS)

    Marichev, V. A.

    2005-08-01

    In DFT calculation of the charge transfer (Δ N), anions pose a special problem since their electron affinities are unknown. There is no method for calculating reasonable values of the absolute electronegativity ( χA) and chemical hardness ( ηA) for ions from data of species themselves. We propose a new approach to the experimental measurement of χA at the condition: Δ N = 0 at which η values may be neglected and χA = χMe. Electrochemical parameters corresponding to this condition may be obtained by the contact electric resistance method during in situ investigation of anion adsorption in the particular system anion-metal.

  19. Response surface modeling of acid activation of raw diatomite using in sunflower oil bleaching by: Box-Behnken experimental design.

    PubMed

    Larouci, M; Safa, M; Meddah, B; Aoues, A; Sonnet, P

    2015-03-01

    The optimum conditions for acid activation of diatomite for maximizing bleaching efficiency of the diatomite in sun flower oil treatment were studied. Box-Behnken experimental design combining with response surface modeling (RSM) and quadratic programming (QP) was employed to obtain the optimum conditions of three independent variables (acid concentration, activation time and solid to liquid) for acid activation of diatomite. The significance of independent variables and their interactions were tested by means of the analysis of variance (ANOVA) with 95 % confidence limits (α = 0.05). The optimum values of the selected variables were obtained by solving the quadratic regression model, as well as by analyzing the response surface contour plots. The experimental conditions at this global point were determined to be acid concentration = 8.963 N, activation time = 11.9878 h, and solid to liquid ratio = 221.2113 g/l, the corresponding bleaching efficiency was found to be about 99 %.

  20. Partial Adaptation of Obtained and Observed Value Signals Preserves Information about Gains and Losses

    PubMed Central

    Baddeley, Michelle; Tobler, Philippe N.; Schultz, Wolfram

    2016-01-01

    Given that the range of rewarding and punishing outcomes of actions is large but neural coding capacity is limited, efficient processing of outcomes by the brain is necessary. One mechanism to increase efficiency is to rescale neural output to the range of outcomes expected in the current context, and process only experienced deviations from this expectation. However, this mechanism comes at the cost of not being able to discriminate between unexpectedly low losses when times are bad versus unexpectedly high gains when times are good. Thus, too much adaptation would result in disregarding information about the nature and absolute magnitude of outcomes, preventing learning about the longer-term value structure of the environment. Here we investigate the degree of adaptation in outcome coding brain regions in humans, for directly experienced outcomes and observed outcomes. We scanned participants while they performed a social learning task in gain and loss blocks. Multivariate pattern analysis showed two distinct networks of brain regions adapt to the most likely outcomes within a block. Frontostriatal areas adapted to directly experienced outcomes, whereas lateral frontal and temporoparietal regions adapted to observed social outcomes. Critically, in both cases, adaptation was incomplete and information about whether the outcomes arose in a gain block or a loss block was retained. Univariate analysis confirmed incomplete adaptive coding in these regions but also detected nonadapting outcome signals. Thus, although neural areas rescale their responses to outcomes for efficient coding, they adapt incompletely and keep track of the longer-term incentives available in the environment. SIGNIFICANCE STATEMENT Optimal value-based choice requires that the brain precisely and efficiently represents positive and negative outcomes. One way to increase efficiency is to adapt responding to the most likely outcomes in a given context. However, too strong adaptation would result

  1. Studying the specific features pertinent to combustion of chars obtained from coals having different degrees of metamorphism and biomass chars

    NASA Astrophysics Data System (ADS)

    Bestsennyi, I. V.; Shchudlo, T. S.; Dunaevskaya, N. I.; Topal, A. I.

    2013-12-01

    Better conditions for igniting low-reaction coal (anthracite) can be obtained, higher fuel burnout ratio can be achieved, and the problem of shortage of a certain grade of coal can be solved by firing coal mixtures and by combusting coal jointly with solid biomass in coal-fired boilers. Results from studying the synergetic effect that had been revealed previously during the combustion of coal mixtures in flames are presented. A similar effect was also obtained during joint combustion of coal and wood in a flame. The kinetics pertinent to combustion of char mixtures obtained from coals characterized by different degrees of metamorphism and the kinetics pertinent to combustion of wood chars were studied on the RSK-1D laboratory setup. It was found from the experiments that the combustion rate of char mixtures obtained from coals having close degrees of metamorphism is equal to the value determined as a weighted mean rate with respect to the content of carbon. The combustion rate of char mixtures obtained from coals having essentially different degrees of metamorphism is close to the combustion rate of more reactive coal initially in the process and to the combustion rate of less reactive coal at the end of the process. A dependence of the specific burnout rate of carbon contained in the char of two wood fractions on reciprocal temperature in the range 663—833 K is obtained. The combustion mode of an experimental sample is determined together with the reaction rate constant and activation energy.

  2. 76 FR 76422 - Agency Information Collection Activities; Proposed Collection; Comment Request; Experimental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ...] Agency Information Collection Activities; Proposed Collection; Comment Request; Experimental Study on Comparing Data Obtained From Landline Telephone and Cell Phone Surveys AGENCY: Food and Drug Administration... notice. This notice solicits comments on a study entitled ``Experimental Study on Comparing Data Obtained...

  3. Experimental Verification of the Individual Energy Dependencies of the Partial L-Shell Photoionization Cross Sections of Pd and Mo

    NASA Astrophysics Data System (ADS)

    Hönicke, Philipp; Kolbe, Michael; Müller, Matthias; Mantler, Michael; Krämer, Markus; Beckhoff, Burkhard

    2014-10-01

    An experimental method for the verification of the individually different energy dependencies of L1-, L2-, and L3- subshell photoionization cross sections is described. The results obtained for Pd and Mo are well in line with theory regarding both energy dependency and absolute values, and confirm the theoretically calculated cross sections by Scofield from the early 1970 s and, partially, more recent data by Trzhaskovskaya, Nefedov, and Yarzhemsky. The data also demonstrate the questionability of quantitative x-ray spectroscopical results based on the widely used fixed jump ratio approximated cross sections with energy independent ratios. The experiments are carried out by employing the radiometrically calibrated instrumentation of the Physikalisch-Technische Bundesanstalt at the electron storage ring BESSY II in Berlin; the obtained fluorescent intensities are thereby calibrated at an absolute level in reference to the International System of Units. Experimentally determined fixed fluorescence line ratios for each subshell are used for a reliable deconvolution of overlapping fluorescence lines. The relevant fundamental parameters of Mo and Pd are also determined experimentally in order to calculate the subshell photoionization cross sections independently of any database.

  4. Working harder to obtain more snack foods when wanting to eat less.

    PubMed

    Giesen, Janneke C A H; Havermans, Remco C; Nederkoorn, Chantal; Strafaci, Silvana; Jansen, Anita

    2009-01-01

    This study investigates individual differences in the reinforcing value of snack food. More specifically, it was investigated whether differences in restraint status are associated with differences in working for high-caloric snack food. Thirty-six unrestrained non-dieters, twenty restrained non-dieters and fifteen current dieters performed a concurrent schedules task in which they had the option to work for points for either snack food or fruit and vegetables. By progressively increasing the "price" of the snack foods (i.e., the amount of work required to obtain extra snack points) the relative reinforcing value of snack food was determined. As hypothesized, restrained non-dieters worked harder and current dieters worked less hard to obtain snack food as compared to unrestrained non-dieters.

  5. Biosensors for monitoring the isothermal breakdown kinetics of peanut oil heated at 180°C. Comparison with results obtained for extra virgin olive oil.

    PubMed

    Tomassetti, M; Vecchio, S; Campanella, L; Dragone, R

    2013-10-15

    The present research was devoted to studying the kinetics of the artificial rancidification of peanut oil (PO) when a sample of this oil was isothermally heated at 180°C in an air stream. The formation of radical species due to heating was evaluated using a radical index whose value was determined using a biosensor method based on a superoxide dismutase (SOD), while the increasing toxicity was monitored using a suitable toxicity measuring probe based on the Clark electrode and immobilized yeast cells. An extra virgin olive oil was isothermally rancidified under the same experimental conditions and the corresponding data were used for the purpose of comparison. Both the so-called "model-fitting" and the classical kinetic methods were applied to the isothermal process biosensor data in order to obtain the kinetic constant rate value at 180°C. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. Experimental Investigation of the Flow on a Simple Frigate Shape (SFS)

    PubMed Central

    Mora, Rafael Bardera

    2014-01-01

    Helicopters operations on board ships require special procedures introducing additional limitations known as ship helicopter operational limitations (SHOLs) which are a priority for all navies. This paper presents the main results obtained from the experimental investigation of a simple frigate shape (SFS) which is a typical case of study in experimental and computational aerodynamics. The results obtained in this investigation are used to make an assessment of the flow predicted by the SFS geometry in comparison with experimental data obtained testing a ship model (reduced scale) in the wind tunnel and on board (full scale) measurements performed on a real frigate type ship geometry. PMID:24523646

  7. Multicomponent Diffusion in Experimentally Cooled Melt Inclusions

    NASA Astrophysics Data System (ADS)

    Saper, L.; Stolper, E.

    2017-12-01

    Glassy olivine-hosted melt inclusions are compositionally zoned, characterized by a boundary layer depleted in olivine-compatible components that extends into the melt inclusion from its wall. The boundary layer forms in response to crystallization of olivine and relaxes with time due to diffusive exchange with the interior of the inclusion. At magmatic temperatures, the time scale for homogenization of inclusions is minutes to hours. Preservation of compositional gradients in natural inclusions results from rapid cooling upon eruption. A model of MgO concentration profiles that couples crystal growth and diffusive relaxation of a boundary layer can be used to solve for eruptive cooling rates [1]. Controlled cooling-rate experiments were conducted to test the accuracy of the model. Mauna Loa olivine containing >80 µm melt inclusions were equilibrated at 1225°C in a 1-atm furnace for 24 hours, followed by linear cooling at rates of 102 - 105 °C/hr. High-resolution concentration profiles of 40 inclusions were obtained using an electron microprobe. The model of [1] fits the experimental data with low residuals and the best-fit cooling rates are within 30% of experimental values. The initial temperature of 1225 °C is underestimated by 65°C. The model was modified using (i) MELTS to calculate the interface melt composition as a function of temperature, and (ii) a concentration-dependent MgO diffusion coefficient using the functional form of [2]. With this calibration the best-fit starting temperatures are within 5°C of the experimental values and the best-fit cooling rates are within 20% of experimental rates. The evolution of the CaO profile during cooling is evidence for strong diffusive coupling between melt components. Because CaO is incompatible in olivine, CaO concentrations are expected to be elevated in the boundary layer adjacent to the growing olivine. Although this is observed at short time scales, as the profile evolves the CaO concentration near the

  8. Electric Propulsion: Experimental Research

    NASA Technical Reports Server (NTRS)

    Ruyten, W. M.; Friedly, V. J.; Keefer, D.

    1995-01-01

    This paper describes experimental electric propulsion research which was carried out at the University of Tennessee Space Institute with support from the Center for Space Transportation and Applied Research. Specifically, a multiplexed LIF technique for obtaining vector velocities, Doppler temperatures, and relative number densities in the exhaust plumes form electric propulsion devices is described, and results are presented that were obtained on a low power argon arcjet. Also, preliminary Langmuir probe measurements on an ion source are described, and an update on the vacuum facility is presented.

  9. Experimental and computational thermochemical study and solid-phase structure of 5,5-dimethylbarbituric acid.

    PubMed

    Roux, María Victoria; Notario, Rafael; Foces-Foces, Concepción; Temprado, Manuel; Ros, Francisco; Emel'yanenko, Vladimir N; Verevkin, Sergey P

    2010-03-18

    This paper reports an experimental and computational thermochemical study on 5,5-dimethylbarbituric acid and the solid-phase structure of the compound. The value of the standard (p(o) = 0.1 MPa) molar enthalpy of formation in the gas phase at T = 298.15 K has been determined. The energy of combustion was measured by static bomb combustion calorimetry, and from the result obtained, the standard molar enthalpy of formation in the crystalline state at T = 298.15 K was calculated as -(706.4 +/- 2.2) kJ x mol(-1). The enthalpy of sublimation was determined using a transference (transpiration) method in a saturated NB(2) stream, and a value of the enthalpy of sublimation at T = 298.15 K was derived as (115.8 +/- 0.5) kJ x mol(-1). From these results a value of -(590.6 +/- 2.3) kJ x mol(-1) for the gas-phase enthalpy of formation at T = 298.15 K was determined. Theoretical calculations at the G3 level were performed, and a study on molecular and electronic structure of the compound has been carried out. Calculated enthalpies of formation are in reasonable agreement with the experimental value. 5,5-Dimethylbarbituric acid was characterized by single crystal X-ray diffraction analysis. In the crystal structure, N-H...O=C hydrogen bonds lead to the formation of ribbons connected further by weak C-H...O=C hydrogen bonds into a three-dimensional network. The molecular and supramolecular structures observed in the solid state were also investigated in the gas phase by DFT calculations.

  10. 12 CFR 703.11 - Valuing securities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 7 2014-01-01 2014-01-01 false Valuing securities. 703.11 Section 703.11 Banks... DEPOSIT ACTIVITIES § 703.11 Valuing securities. (a) Before purchasing or selling a security, a Federal credit union must obtain either price quotations on the security from at least two broker-dealers or a...

  11. Effects of b-value and number of gradient directions on diffusion MRI measures obtained with Q-ball imaging

    NASA Astrophysics Data System (ADS)

    Schilling, Kurt G.; Nath, Vishwesh; Blaber, Justin; Harrigan, Robert L.; Ding, Zhaohua; Anderson, Adam W.; Landman, Bennett A.

    2017-02-01

    High-angular-resolution diffusion-weighted imaging (HARDI) MRI acquisitions have become common for use with higher order models of diffusion. Despite successes in resolving complex fiber configurations and probing microstructural properties of brain tissue, there is no common consensus on the optimal b-value and number of diffusion directions to use for these HARDI methods. While this question has been addressed by analysis of the diffusion-weighted signal directly, it is unclear how this translates to the information and metrics derived from the HARDI models themselves. Using a high angular resolution data set acquired at a range of b-values, and repeated 11 times on a single subject, we study how the b-value and number of diffusion directions impacts the reproducibility and precision of metrics derived from Q-ball imaging, a popular HARDI technique. We find that Q-ball metrics associated with tissue microstructure and white matter fiber orientation are sensitive to both the number of diffusion directions and the spherical harmonic representation of the Q-ball, and often are biased when under sampled. These results can advise researchers on appropriate acquisition and processing schemes, particularly when it comes to optimizing the number of diffusion directions needed for metrics derived from Q-ball imaging.

  12. Optimizing Methods of Obtaining Stellar Parameters for the H3 Survey

    NASA Astrophysics Data System (ADS)

    Ivory, KeShawn; Conroy, Charlie; Cargile, Phillip

    2018-01-01

    The Stellar Halo at High Resolution with Hectochelle Survey (H3) is in the process of observing and collecting stellar parameters for stars in the Milky Way's halo. With a goal of measuring radial velocities for fainter stars, it is crucial that we have optimal methods of obtaining this and other parameters from the data from these stars.The method currently developed is The Payne, named after Cecilia Payne-Gaposchkin, a code that uses neural networks and Markov Chain Monte Carlo methods to utilize both spectra and photometry to obtain values for stellar parameters. This project was to investigate the benefit of fitting both spectra and spectral energy distributions (SED). Mock spectra using the parameters of the Sun were created and noise was inserted at various signal to noise values. The Payne then fit each mock spectrum with and without a mock SED also generated from solar parameters. The result was that at high signal to noise, the spectrum dominated and the effect of fitting the SED was minimal. But at low signal to noise, the addition of the SED greatly decreased the standard deviation of the data and resulted in more accurate values for temperature and metallicity.

  13. Modelling and Experimental Verification of Pressure Wave Following Gaseous Helium Storage Tank Rupture

    NASA Astrophysics Data System (ADS)

    Chorowski, M.; Grabowski, M.; Jędrusyna, A.; Wach, J.

    Helium inventory in high energy accelerators, tokamaks and free electron lasers may exceed tens of tons. The gaseous helium is stored in steel tanks under a pressure of about 20 bar and at environment temperature. Accidental rupture of any of the tanks filled with the gaseous helium will create a rapid energy release in form of physical blast. An estimation of pressure wave distribution following the tank rupture and potential consequences to the adjacent research infrastructure and buildings is a very important task, critical in the safety aspect of the whole cryogenic system. According to the present regulations the TNT equivalent approach is to be applied to evaluate the pressure wave following a potential gas storage tank rupture. A special test stand was designed and built in order to verify experimentally the blast effects in controlled conditions. In order to obtain such a shock wave a pressurized plastic tank was used. The tank was ruptured and the resulting pressure wave was recorded using a spatially-distributed array of pressure sensors connected to a high-speed data acquisition device. The results of the experiments and the comparison with theoretical values obtained from thermodynamic model of the blast are presented. A good agreement between the simulated and measured data was obtained. Recommendations regarding the applicability of thermodynamic model of physical blast versus TNT approach, to estimate consequences of gas storage tank rupture are formulated. The laboratory scale experimental results have been scaled to ITER pressurized helium storage tanks.

  14. Acid-adapted strains of Escherichia coli K-12 obtained by experimental evolution.

    PubMed

    Harden, Mark M; He, Amanda; Creamer, Kaitlin; Clark, Michelle W; Hamdallah, Issam; Martinez, Keith A; Kresslein, Robert L; Bush, Sean P; Slonczewski, Joan L

    2015-03-01

    Enteric bacteria encounter a wide range of pHs throughout the human intestinal tract. We conducted experimental evolution of Escherichia coli K-12 to isolate clones with increased fitness during growth under acidic conditions (pH 4.5 to 4.8). Twenty-four independent populations of E. coli K-12 W3110 were evolved in LBK medium (10 g/liter tryptone, 5 g/liter yeast extract, 7.45 g/liter KCl) buffered with homopiperazine-N,N'-bis-2-(ethanosulfonic acid) and malate at pH 4.8. At generation 730, the pH was decreased to 4.6 with HCl. By 2,000 generations, all populations had achieved higher endpoint growth than the ancestor at pH 4.6 but not at pH 7.0. All evolving populations showed a progressive loss of activity of lysine decarboxylase (CadA), a major acid stress enzyme. This finding suggests a surprising association between acid adaptation and moderation of an acid stress response. At generation 2,000, eight clones were isolated from four populations, and their genomes were sequenced. Each clone showed between three and eight missense mutations, including one in a subunit of the RNA polymerase holoenzyme (rpoB, rpoC, or rpoD). Missense mutations were found in adiY, the activator of the acid-inducible arginine decarboxylase (adiA), and in gcvP (glycine decarboxylase), a possible acid stress component. For tests of fitness relative to that of the ancestor, lacZ::kan was transduced into each strain. All acid-evolved clones showed a high fitness advantage at pH 4.6. With the cytoplasmic pH depressed by benzoate (at external pH 6.5), acid-evolved clones showed decreased fitness; thus, there was no adaptation to cytoplasmic pH depression. At pH 9.0, acid-evolved clones showed no fitness advantage. Thus, our acid-evolved clones showed a fitness increase specific to low external pH. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  15. Acid-Adapted Strains of Escherichia coli K-12 Obtained by Experimental Evolution

    PubMed Central

    Harden, Mark M.; He, Amanda; Creamer, Kaitlin; Clark, Michelle W.; Hamdallah, Issam; Martinez, Keith A.; Kresslein, Robert L.; Bush, Sean P.

    2015-01-01

    Enteric bacteria encounter a wide range of pHs throughout the human intestinal tract. We conducted experimental evolution of Escherichia coli K-12 to isolate clones with increased fitness during growth under acidic conditions (pH 4.5 to 4.8). Twenty-four independent populations of E. coli K-12 W3110 were evolved in LBK medium (10 g/liter tryptone, 5 g/liter yeast extract, 7.45 g/liter KCl) buffered with homopiperazine-N,N′-bis-2-(ethanosulfonic acid) and malate at pH 4.8. At generation 730, the pH was decreased to 4.6 with HCl. By 2,000 generations, all populations had achieved higher endpoint growth than the ancestor at pH 4.6 but not at pH 7.0. All evolving populations showed a progressive loss of activity of lysine decarboxylase (CadA), a major acid stress enzyme. This finding suggests a surprising association between acid adaptation and moderation of an acid stress response. At generation 2,000, eight clones were isolated from four populations, and their genomes were sequenced. Each clone showed between three and eight missense mutations, including one in a subunit of the RNA polymerase holoenzyme (rpoB, rpoC, or rpoD). Missense mutations were found in adiY, the activator of the acid-inducible arginine decarboxylase (adiA), and in gcvP (glycine decarboxylase), a possible acid stress component. For tests of fitness relative to that of the ancestor, lacZ::kan was transduced into each strain. All acid-evolved clones showed a high fitness advantage at pH 4.6. With the cytoplasmic pH depressed by benzoate (at external pH 6.5), acid-evolved clones showed decreased fitness; thus, there was no adaptation to cytoplasmic pH depression. At pH 9.0, acid-evolved clones showed no fitness advantage. Thus, our acid-evolved clones showed a fitness increase specific to low external pH. PMID:25556191

  16. Experimental density measurements of bis(2-ethylhexyl) phthalate at elevated temperatures and pressures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bamgbade, Babatunde A; Wu, Yue; Baled, Hseen O

    2013-08-01

    Experimental high-temperature, high-pressure (HTHP) density data for bis(2-ethylhexyl) phthalate (DEHP) are reported in this study. DEHP is a popular choice as a reference fluid for viscosity calibrations in the HTHP region. However, reliable HTHP density values are needed for accurate viscosity calculations for certain viscometers (e.g. rolling ball). HTHP densities are determined at T = (373, 424, 476, 492, and 524) K and P to 270 MPa using a variable-volume, high-pressure view cell. The experimental density data are satisfactorily correlated by the modified Tait equation with a mean absolute percent deviation (δ) of 0.15. The experimental data are modeled withmore » the Peng–Robinson (PREoS), volume-translated PREoS (VT-PREoS), and perturbed chain statistical associating fluid theory (PC-SAFT EoS) models. The required parameters for the two PREoS and the PC-SAFT EoS models are determined using group contribution methods. The PC-SAFT EoS performs the best of the three models with a δ of 2.12. The PC-SAFT EoS is also fit to the experimental data to obtain a new set of pure component parameters that yield a δ of 0.20 for these HTHP conditions.« less

  17. Experimental designs for a Benign Paroxysmal Positional Vertigo model

    PubMed Central

    2013-01-01

    Background The pathology of the Benign Paroxysmal Positional Vertigo (BPPV) is detected by a clinician through maneuvers consisting of a series of consecutive head turns that trigger the symptoms of vertigo in patient. A statistical model based on a new maneuver has been developed in order to calculate the volume of endolymph displaced after the maneuver. Methods A simplification of the Navier‐Stokes problem from the fluids theory has been used to construct the model. In addition, the same cubic splines that are commonly used in kinematic control of robots were used to obtain an appropriate description of the different maneuvers. Then experimental designs were computed to obtain an optimal estimate of the model. Results D‐optimal and c‐optimal designs of experiments have been calculated. These experiments consist of a series of specific head turns of duration Δt and angle α that should be performed by the clinician on the patient. The experimental designs obtained indicate the duration and angle of the maneuver to be performed as well as the corresponding proportion of replicates. Thus, in the D‐optimal design for 100 experiments, the maneuver consisting of a positive 30° pitch from the upright position, followed by a positive 30° roll, both with a duration of one and a half seconds is repeated 47 times. Then the maneuver with 60° /6° pitch/roll during half a second is repeated 16 times and the maneuver 90° /90° pitch/roll during half a second is repeated 37 times. Other designs with significant differences are computed and compared. Conclusions A biomechanical model was derived to provide a quantitative basis for the detection of BPPV. The robustness study for the D‐optimal design, with respect to the choice of the nominal values of the parameters, shows high efficiencies for small variations and provides a guide to the researcher. Furthermore, c‐optimal designs give valuable assistance to check how efficient the D‐optimal design is for the

  18. Singular-value demodulation of phase-shifted holograms.

    PubMed

    Lopes, Fernando; Atlan, Michael

    2015-06-01

    We report on phase-shifted holographic interferogram demodulation by singular-value decomposition. Numerical processing of optically acquired interferograms over several modulation periods was performed in two steps: (1) rendering of off-axis complex-valued holograms by Fresnel transformation of the interferograms; and (2) eigenvalue spectrum assessment of the lag-covariance matrix of hologram pixels. Experimental results in low-light recording conditions were compared with demodulation by Fourier analysis, in the presence of random phase drifts.

  19. System parameters for erythropoiesis control model: Comparison of normal values in human and mouse model

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The computer model for erythropoietic control was adapted to the mouse system by altering system parameters originally given for the human to those which more realistically represent the mouse. Parameter values were obtained from a variety of literature sources. Using the mouse model, the mouse was studied as a potential experimental model for spaceflight. Simulation studies of dehydration and hypoxia were performed. A comparison of system parameters for the mouse and human models is presented. Aside from the obvious differences expected in fluid volumes, blood flows and metabolic rates, larger differences were observed in the following: erythrocyte life span, erythropoietin half-life, and normal arterial pO2.

  20. Problems in obtaining perfect images by single-particle electron cryomicroscopy of biological structures in amorphous ice.

    PubMed

    Henderson, Richard; McMullan, Greg

    2013-02-01

    Theoretical considerations together with simulations of single-particle electron cryomicroscopy images of biological assemblies in ice demonstrate that atomic structures should be obtainable from images of a few thousand asymmetric units, provided the molecular weight of the whole assembly being studied is greater than the minimum needed for accurate position and orientation determination. However, with present methods of specimen preparation and current microscope and detector technologies, many more particles are needed, and the alignment of smaller assemblies is difficult or impossible. Only larger structures, with enough signal to allow good orientation determination and with enough images to allow averaging of many hundreds of thousands or even millions of asymmetric units, have successfully produced high-resolution maps. In this review, we compare the contrast of experimental electron cryomicroscopy images of two smaller molecular assemblies, namely apoferritin and beta-galactosidase, with that expected from perfect simulated images calculated from their known X-ray structures. We show that the contrast and signal-to-noise ratio of experimental images still require significant improvement before it will be possible to realize the full potential of single-particle electron cryomicroscopy. In particular, although reasonably good orientations can be obtained for beta-galactosidase, we have been unable to obtain reliable orientation determination from experimental images of apoferritin. Simulations suggest that at least 2-fold improvement of the contrast in experimental images at ~10 Å resolution is needed and should be possible.

  1. Are preference and resistance to change convergent expressions of stimulus value?

    PubMed

    Podlesnik, Christopher A; Jimenez-Gomez, Corina; Shahan, Timothy A

    2013-07-01

    Behavioral momentum theory asserts that preference and relative resistance to disruption depend on reinforcement rates and provide converging expressions of the conditioned value of discriminative stimuli. However, preference and resistance to disruption diverge when assessing preference during brief extinction probes. We expanded upon this opposing relation by arranging target stimuli signaling equal variable-interval schedules across components of a multiple schedule. We paired one target stimulus with a richer reinforced alternative and the other with a leaner alternative. Furthermore, we varied reinforcement rates for the paired alternatives to assess the effects of manipulating relative conditioned value on preference and resistance to disruption by presession feeding, intercomponent food, and extinction. We replicated the opposing relation between preference and resistance to disruption but varying reinforcement rates for the paired alternatives did not systematically affect preference or resistance to disruption beyond levels observed in our initial condition. Importantly, we found that only preference between the target stimuli was related to relative baseline response rates in the presence of those stimuli. These findings suggest that preference during extinction probes might reveal more about baseline response rates between concurrently available alternatives than relative conditioned value. Resistance to disruption, conversely, appears to better reflect conditioned value because it is less confounded with baseline response rates and is a function of all sources of reinforcement obtained in the presence of a stimulus context. © Society for the Experimental Analysis of Behavior.

  2. Damage identification of beam structures using free response shapes obtained by use of a continuously scanning laser Doppler vibrometer system

    NASA Astrophysics Data System (ADS)

    Xu, Y. F.; Chen, Da-Ming; Zhu, W. D.

    2017-08-01

    Spatially dense operating deflection shapes and mode shapes can be rapidly obtained by use of a continuously scanning laser Doppler vibrometer (CSLDV) system, which sweeps its laser spot over a vibrating structure surface. This paper introduces a new type of vibration shapes called a free response shape (FRS) that can be obtained by use of a CSLDV system, and a new damage identification methodology using FRSs is developed for beam structures. An analytical expression of FRSs of a damped beam structure is derived, and FRSs from the analytical expression compare well with those from a finite element model. In the damage identification methodology, a free-response damage index (FRDI) is proposed, and damage regions can be identified near neighborhoods with consistently high values of FRDIs associated with different modes; an auxiliary FRDI is defined to assist identification of the neighborhoods. A FRDI associated with a mode consists of differences between curvatures of FRSs associated with the mode in a number of half-scan periods of a CSLDV system and those from polynomials that fit the FRSs with properly determined orders. A convergence index is proposed to determine the proper order of a polynomial fit. One advantage of the methodology is that the FRDI does not require any baseline information of an undamaged beam structure, if it is geometrically smooth and made of materials that have no stiffness and mass discontinuities. Another advantage is that FRDIs associated with multiple modes can be obtained using free response of a beam structure measured by a CSLDV system in one scan. The number of half-scan periods for calculation of the FRDI associated with a mode can be determined by use of the short-time Fourier transform. The proposed methodology was numerically and experimentally applied to identify damage in beam structures; effects of the scan frequency of a CSLDV system on qualities of obtained FRSs were experimentally investigated.

  3. FIB preparation of a NiO Wedge-Lamella and STEM X-ray microanalysis for the determination of the experimental k(O-Ni) Cliff-Lorimer coefficient.

    PubMed

    Armigliato, Aldo; Frabboni, Stefano; Gazzadi, Gian Carlo; Rosa, Rodolfo

    2013-02-01

    A method for the fabrication of a wedge-shaped thin NiO lamella by focused ion beam is reported. The starting sample is an oxidized bulk single crystalline, <100> oriented, Ni commercial standard. The lamella is employed for the determination, by analytical electron microscopy at 200 kV of the experimental k(O-Ni) Cliff-Lorimer (G. Cliff & G.W. Lorimer, J Microsc 103, 203-207, 1975) coefficient, according to the extrapolation method by Van Cappellen (E. Van Cappellen, Microsc Microstruct Microanal 1, 1-22, 1990). The result thus obtained is compared to the theoretical k(O-Ni) values either implemented into the commercial software for X-ray microanalysis quantification of the scanning transmission electron microscopy/energy dispersive spectrometry equipment or calculated by the Monte Carlo method. Significant differences among the three values are found. This confirms that for a reliable quantification of binary alloys containing light elements, the choice of the Cliff-Lorimer coefficients is crucial and experimental values are recommended.

  4. Validations of calibration-free measurements of electron temperature using double-pass Thomson scattering diagnostics from theoretical and experimental aspects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tojo, H., E-mail: tojo.hiroshi@qst.go.jp; Hiratsuka, J.; Yatsuka, E.

    2016-09-15

    This paper evaluates the accuracy of electron temperature measurements and relative transmissivities of double-pass Thomson scattering diagnostics. The electron temperature (T{sub e}) is obtained from the ratio of signals from a double-pass scattering system, then relative transmissivities are calculated from the measured T{sub e} and intensity of the signals. How accurate the values are depends on the electron temperature (T{sub e}) and scattering angle (θ), and therefore the accuracy of the values was evaluated experimentally using the Large Helical Device (LHD) and the Tokyo spherical tokamak-2 (TST-2). Analyzing the data from the TST-2 indicates that a high T{sub e} andmore » a large scattering angle (θ) yield accurate values. Indeed, the errors for scattering angle θ = 135° are approximately half of those for θ = 115°. The method of determining the T{sub e} in a wide T{sub e} range spanning over two orders of magnitude (0.01–1.5 keV) was validated using the experimental results of the LHD and TST-2. A simple method to provide relative transmissivities, which include inputs from collection optics, vacuum window, optical fibers, and polychromators, is also presented. The relative errors were less than approximately 10%. Numerical simulations also indicate that the T{sub e} measurements are valid under harsh radiation conditions. This method to obtain T{sub e} can be considered for the design of Thomson scattering systems where there is high-performance plasma that generates harsh radiation environments.« less

  5. Effect of Nano-CuO on Engineering and Microstructure Properties of Fibre-Reinforced Mortars Incorporating Metakaolin: Experimental and Numerical Studies

    PubMed Central

    Ghanei, Amir; Jafari, Faezeh; Mehrinejad Khotbehsara, Mojdeh; Mohseni, Ehsan; Cui, Hongzhi

    2017-01-01

    In this study, the effects of nano-CuO (NC) on engineering properties of fibre-reinforced mortars incorporating metakaolin (MK) were investigated. The effects of polypropylene fibre (PP) were also examined. A total of twenty-six mixtures were prepared. The experimental results were compared with numerical results obtained by adaptive neuro-fuzzy inference system (ANFIS) and Primal Estimated sub-GrAdient Solver for SVM (Pegasos) algorithm. Scanning Electron Microscope (SEM) was also employed to investigate the microstructure of the cement matrix. The mechanical test results showed that both compressive and flexural strengths of cement mortars decreased with the increase of MK content, however the strength values increased significantly with increasing NC content in the mixture. The water absorption of samples decreased remarkably with increasing NC particles in the mixture. When PP fibres were added, the strengths of cement mortars were further enhanced accompanied with lower water absorption values. The addition of 2 wt % and 3 wt % nanoparticles in cement mortar led to a positive contribution to strength and resistance to water absorption. Mixture of PP-MK10NC3 indicated the best results for both compressive and flexural strengths at 28 and 90 days. SEM images illustrated that the morphology of cement matrix became more porous with increasing MK content, but the porosity reduced with the inclusion of NC. In addition, it is evident from the SEM images that more cement hydration products adhered onto the surface of fibres, which would improve the fibre–matrix interface. The numerical results obtained by ANFIS and Pegasos were close to the experimental results. The value of R2 obtained for each data set (validate, test and train) was higher than 0.90 and the values of mean absolute percentage error (MAPE) and the relative root mean squared error (PRMSE) were near zero. The ANFIS and Pegasos models can be used to predict the mechanical properties and water

  6. Effect of storage conditions on the calorific value of municipal solid waste.

    PubMed

    Nzioka, Antony Mutua; Hwang, Hyeon-Uk; Kim, Myung-Gyun; Yan, Cao Zheng; Lee, Chang-Soo; Kim, Young-Ju

    2017-08-01

    Storage conditions are considered to be an important factor as far as waste material characteristics are concerned. This experimental investigation was conducted using municipal solid waste (MSW) with a high moisture content and varying composition of organic waste. The objective of this study was to understand the effect of storage conditions and temperature on the moisture content and calorific value of the waste. Samples were subjected to two different storage conditions and investigated at specified temperatures. The composition of sample materials investigated was varied for each storage condition and temperature respectively. Gross calorific value was determined experimentally while net calorific value was calculated using empirical formulas proposed by other researchers. Results showed minimal changes in moisture content as well as in gross and net calorific values when the samples were subjected to sealed storage conditions. Moisture content reduced due to the ventilation process and the rate of moisture removal increased with a rise in storage temperature. As expected, rate of moisture removal had a positive effect on gross and net calorific values. Net calorific values also increased at varying rates with a simultaneous decrease in moisture content. Experimental investigation showed the effectiveness of ventilation in improving the combustion characteristics of the waste.

  7. An evaluation of the accuracy of geomagnetic data obtained from an unattended, automated, quasi-absolute station

    USGS Publications Warehouse

    Herzog, D.C.

    1990-01-01

    A comparison is made of geomagnetic calibration data obtained from a high-sensitivity proton magnetometer enclosed within an orthogonal bias coil system, with data obtained from standard procedures at a mid-latitude U.S. Geological Survey magnetic observatory using a quartz horizontal magnetometer, a Ruska magnetometer, and a total field magnetometer. The orthogonal coil arrangement is used with the proton magnetometer to provide Deflected-Inclination-Deflected-Declination (DIDD) data from which quasi-absolute values of declination, horizontal intensity, and vertical intensity can be derived. Vector magnetometers provide the ordinate values to yield baseline calibrations for both the DIDD and standard observatory processes. Results obtained from a prototype system over a period of several months indicate that the DIDD unit can furnish adequate absolute field values for maintaining observatory calibration data, thus providing baseline control for unattended, remote stations. ?? 1990.

  8. Raman bands in Ag nanoparticles obtained in extract of Opuntia ficus-indica plant

    NASA Astrophysics Data System (ADS)

    Bocarando-Chacon, J.-G.; Cortez-Valadez, M.; Vargas-Vazquez, D.; Rodríguez Melgarejo, F.; Flores-Acosta, M.; Mani-Gonzalez, P. G.; Leon-Sarabia, E.; Navarro-Badilla, A.; Ramírez-Bon, R.

    2014-05-01

    Silver nanoparticles have been obtained in an extract of Opuntia ficus-indica plant. The size and distribution of nanoparticles were quantified by atomic force microscopy (AFM). The diameter was estimated to be about 15 nm. In addition, energy dispersive X-ray spectroscopy (EDX) peaks of silver were observed in these samples. Three Raman bands have been experimentally detected at 83, 110 and 160 cm-1. The bands at 83 and 110 cm-1 are assigned to the silver-silver Raman modes (skeletal modes) and the Raman mode located at 160 cm-1 has been assigned to breathing modes. Vibrational assignments of Raman modes have been carried out based on the Density Functional Theory (DFT) quantum mechanical calculation. Structural and vibrational properties for small Agn clusters with 2≤n≤9 were determined. Calculated Raman modes for small metal clusters have an approximation trend of Raman bands. These Raman bands were obtained experimentally for silver nanoparticles (AgNP).

  9. Tailoring of physical properties in highly filled experimental nanohybrid resin composites.

    PubMed

    Pick, Bárbara; Pelka, Matthias; Belli, Renan; Braga, Roberto R; Lohbauer, Ulrich

    2011-07-01

    To assess the elastic modulus (EM), volumetric shrinkage (VS), and polymerization shrinkage stress (PSS) of experimental highly filled nanohybrid composites as a function of matrix composition, filler distribution, and density. One regular viscosity nanohybrid composite (Grandio, VOCO, Germany) and one flowable nanohybrid composite (Grandio Flow, VOCO) were tested as references along with six highly filled experimental nanohybrid composites (four Bis-GMA-based, one UDMA-based, and one Ormocer®-based). The experimental composites varied in filler size and density. EM values were obtained from the "three-point bending" load-displacement curve. VS was calculated with Archimedes' buoyancy principle. PSS was determined in 1-mm thick specimens placed between two (poly)methyl methacrylate rods (Ø=6mm) attached to an universal testing machine. Data were analyzed using oneway ANOVA, Tukey's test (α=0.05), and linear regression analyses. The flowable composite exhibited the highest VS and PSS but lowest EM. The PSS was significantly lower with Ormocer. The EM was significantly higher among experimental composites with highest filler levels. No significant differences were found between all other experimental composites regarding VS and PSS. Filler density and size did not influence EM, VS, or PSS. Neither the filler configuration nor matrix composition in the investigated materials significantly influenced composite shrinkage and mechanical properties. The highest filled experimental composite seemed to increase EM by keeping VS and PSS low; however, matrix composition seemed to be the determinant factor for shrinkage and stress development. The Ormocer, with reduced PSS, deserves further investigation. Filler size and density did not influence the tested parameters. Copyright © 2011 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  10. Experimental study of the oscillating flow characteristics for a regenerator in a pulse tube cryocooler

    NASA Astrophysics Data System (ADS)

    Ju, Yonglin; Jiang, Yan; Zhou, Yuan

    A dynamic experimental apparatus was designed and constructed to investigate oscillating flow characteristics in a regenerator subjected to a periodically reversing flow established by means of a self-made linear compressor. Detailed experimental data of oscillating pressure drops and phase shift characteristics for regenerators in a high frequency pulse tube cryocooler with an operating frequency of 50 Hz were given. The correlation equations for the maximum and cycle-averaged friction factors in terms of Reynolds numbers and dimensionless distance X were obtained. It was found that the value of the cycle-averaged pressure drop in the oscillating flow across the regenerator is two to three times higher than that of a steady flow at the same Reynolds numbers based on the cross-sectional mean velocity. In addition, the relationship of the phase shifts between the velocity and pressure wave is also discussed.

  11. Experimental test of entangled histories

    NASA Astrophysics Data System (ADS)

    Cotler, Jordan; Duan, Lu-Ming; Hou, Pan-Yu; Wilczek, Frank; Xu, Da; Yin, Zhang-Qi; Zu, Chong

    2017-12-01

    Entangled histories arise when a system partially decoheres in such a way that its past cannot be described by a sequence of states, but rather a superposition of sequences of states. Such entangled histories have not been previously observed. We propose and demonstrate the first experimental scheme to create entangled history states of the Greenberger-Horne-Zeilinger (GHZ) type. In our experiment, the polarization states of a single photon at three different times are prepared as a GHZ entangled history state. We define a GHZ functional which attains a maximum value 1 on the ideal GHZ entangled history state and is bounded above by 1 / 16 for any three-time history state lacking tripartite entanglement. We have measured the GHZ functional on a state we have prepared experimentally, yielding a value of 0 . 656 ± 0 . 005, clearly demonstrating the contribution of entangled histories.

  12. Electric propulsion: Experimental research

    NASA Technical Reports Server (NTRS)

    Ruyten, W. M.; Friedly, V. J.; Keefer, D.

    1992-01-01

    This paper describes experimental electric propulsion research which was carried out at the University of Tennessee Space Institute with support from the Center for Space Transportation and Applied Research. Specifically, a multiplexed laser induced fluorescence (LIF) technique for obtaining vector velocities, Doppler temperatures, and relative number densities in the exhaust plumes from electric propulsion devices is described, and results are presented that were obtained on a low power argon arcjet. Also, preliminary Langmuir probe measurements on an ion source are described, and an update on the vacuum facility is presented.

  13. New optimization scheme to obtain interaction potentials for oxide glasses

    NASA Astrophysics Data System (ADS)

    Sundararaman, Siddharth; Huang, Liping; Ispas, Simona; Kob, Walter

    2018-05-01

    We propose a new scheme to parameterize effective potentials that can be used to simulate atomic systems such as oxide glasses. As input data for the optimization, we use the radial distribution functions of the liquid and the vibrational density of state of the glass, both obtained from ab initio simulations, as well as experimental data on the pressure dependence of the density of the glass. For the case of silica, we find that this new scheme facilitates finding pair potentials that are significantly more accurate than the previous ones even if the functional form is the same, thus demonstrating that even simple two-body potentials can be superior to more complex three-body potentials. We have tested the new potential by calculating the pressure dependence of the elastic moduli and found a good agreement with the corresponding experimental data.

  14. Experimental and computational correlation of fracture parameters KIc, JIc, and GIc for unimodular and bimodular graphite components

    NASA Astrophysics Data System (ADS)

    Bhushan, Awani; Panda, S. K.

    2018-05-01

    The influence of bimodularity (different stress ∼ strain behaviour in tension and compression) on fracture behaviour of graphite specimens has been studied with fracture toughness (KIc), critical J-integral (JIc) and critical strain energy release rate (GIc) as the characterizing parameter. Bimodularity index (ratio of tensile Young's modulus to compression Young's modulus) of graphite specimens has been obtained from the normalized test data of tensile and compression experimentation. Single edge notch bend (SENB) testing of pre-cracked specimens from the same lot have been carried out as per ASTM standard D7779-11 to determine the peak load and critical fracture parameters KIc, GIc and JIc using digital image correlation technology of crack opening displacements. Weibull weakest link theory has been used to evaluate the mean peak load, Weibull modulus and goodness of fit employing two parameter least square method (LIN2), biased (MLE2-B) and unbiased (MLE2-U) maximum likelihood estimator. The stress dependent elasticity problem of three-dimensional crack progression behaviour for the bimodular graphite components has been solved as an iterative finite element procedure. The crack characterizing parameters critical stress intensity factor and critical strain energy release rate have been estimated with the help of Weibull distribution plot between peak loads versus cumulative probability of failure. Experimental and Computational fracture parameters have been compared qualitatively to describe the significance of bimodularity. The bimodular influence on fracture behaviour of SENB graphite has been reflected on the experimental evaluation of GIc values only, which has been found to be different from the calculated JIc values. Numerical evaluation of bimodular 3D J-integral value is found to be close to the GIc value whereas the unimodular 3D J-value is nearer to the JIc value. The significant difference between the unimodular JIc and bimodular GIc indicates that

  15. Weak value amplification considered harmful

    NASA Astrophysics Data System (ADS)

    Ferrie, Christopher; Combes, Joshua

    2014-03-01

    We show using statistically rigorous arguments that the technique of weak value amplification does not perform better than standard statistical techniques for the tasks of parameter estimation and signal detection. We show that using all data and considering the joint distribution of all measurement outcomes yields the optimal estimator. Moreover, we show estimation using the maximum likelihood technique with weak values as small as possible produces better performance for quantum metrology. In doing so, we identify the optimal experimental arrangement to be the one which reveals the maximal eigenvalue of the square of system observables. We also show these conclusions do not change in the presence of technical noise.

  16. Anchoring the Gas-Phase Acidity Scale from Hydrogen Sulfide to Pyrrole. Experimental Bond Dissociation Energies of Nitromethane, Ethanethiol, and Cyclopentadiene.

    PubMed

    Ervin, Kent M; Nickel, Alex A; Lanorio, Jerry G; Ghale, Surja B

    2015-07-16

    A meta-analysis of experimental information from a variety of sources is combined with statistical thermodynamics calculations to refine the gas-phase acidity scale from hydrogen sulfide to pyrrole. The absolute acidities of hydrogen sulfide, methanethiol, and pyrrole are evaluated from literature R-H bond energies and radical electron affinities to anchor the scale. Relative acidities from proton-transfer equilibrium experiments are used in a local thermochemical network optimized by least-squares analysis to obtain absolute acidities of 14 additional acids in the region. Thermal enthalpy and entropy corrections are applied using molecular parameters from density functional theory, with explicit calculation of hindered rotor energy levels for torsional modes. The analysis reduces the uncertainties of the absolute acidities of the 14 acids to within ±1.2 to ±3.3 kJ/mol, expressed as estimates of the 95% confidence level. The experimental gas-phase acidities are compared with calculations, with generally good agreement. For nitromethane, ethanethiol, and cyclopentadiene, the refined acidities can be combined with electron affinities of the corresponding radicals from photoelectron spectroscopy to obtain improved values of the C-H or S-H bond dissociation energies, yielding D298(H-CH2NO2) = 423.5 ± 2.2 kJ mol(-1), D298(C2H5S-H) = 364.7 ± 2.2 kJ mol(-1), and D298(C5H5-H) = 347.4 ± 2.2 kJ mol(-1). These values represent the best-available experimental bond dissociation energies for these species.

  17. Singular Value Decomposition Method to Determine Distance Distributions in Pulsed Dipolar Electron Spin Resonance.

    PubMed

    Srivastava, Madhur; Freed, Jack H

    2017-11-16

    Regularization is often utilized to elicit the desired physical results from experimental data. The recent development of a denoising procedure yielding about 2 orders of magnitude in improvement in SNR obviates the need for regularization, which achieves a compromise between canceling effects of noise and obtaining an estimate of the desired physical results. We show how singular value decomposition (SVD) can be employed directly on the denoised data, using pulse dipolar electron spin resonance experiments as an example. Such experiments are useful in measuring distances and their distributions, P(r) between spin labels on proteins. In noise-free model cases exact results are obtained, but even a small amount of noise (e.g., SNR = 850 after denoising) corrupts the solution. We develop criteria that precisely determine an optimum approximate solution, which can readily be automated. This method is applicable to any signal that is currently processed with regularization of its SVD analysis.

  18. Stereoselective green synthesis and molecular structures of highly functionalized spirooxindole-pyrrolidine hybrids - A combined experimental and theoretical investigation

    NASA Astrophysics Data System (ADS)

    Kumar, Raju Suresh; Almansour, Abdulrahman I.; Arumugam, Natarajan; Soliman, Saied M.; Kumar, Raju Ranjith; Altaf, Mohammad; Ghabbour, Hazem A.; Krishnamoorthy, Bellie Sundaram

    2018-01-01

    Highly functionalized spirooxindole-pyrrolidine hybrids have been synthesized stereoselectively through a [3 + 2] cycloaddition strategy in an ionic liquid, 1-butyl-3-methylimidazolium bromide ([bmim]Br). The structure of these spiro heterocyclic hybrids was elucidated using one and two dimensional NMR spectroscopy, single crystal X-ray crystallographic studies and Density Functional Theory (DFT) calculations. The calculated geometric parameters are in good agreement with the experimental data obtained from the X-ray structures. The Natural Bond Orbital (NBO) calculations on these molecules confirm the electron rich carbonyl oxygen and electron deficient NH groups. The 1H and 13C NMR chemical shifts calculated using GIAO method are in good agreement with the experimental data. The DFT computed polarizability values also suggest the possible NLO activity of these molecules.

  19. Experimental Altitude Performance of JP-4 Fuel and Liquid-Oxygen Rocket Engine with an Area Ratio of 48

    NASA Technical Reports Server (NTRS)

    Fortini, Anthony; Hendrix, Charles D.; Huff, Vearl N.

    1959-01-01

    The performance for four altitudes (sea-level, 51,000, 65,000, and 70,000 ft) of a rocket engine having a nozzle area ratio of 48.39 and using JP-4 fuel and liquid oxygen as a propellant was evaluated experimentally by use of a 1000-pound-thrust engine operating at a chamber pressure of 600 pounds per square inch absolute. The altitude environment was obtained by a rocket-ejector system which utilized the rocket exhaust gases as the pumping fluid of the ejector. Also, an engine having a nozzle area ratio of 5.49 designed for sea level was tested at sea-level conditions. The following table lists values from faired experimental curves at an oxidant-fuel ratio of 2.3 for various approximate altitudes.

  20. Experimental and constitutive modeling approaches for a study of biomechanical properties of human coronary arteries.

    PubMed

    Jankowska, Malgorzata A; Bartkowiak-Jowsa, Magdalena; Bedzinski, Romuald

    2015-10-01

    The study concerns the determination of mechanical properties of human coronary arterial walls with both experimental and constitutive modeling approaches. The research material was harvested from 18 patients (range 50-84 years). On the basis of hospital records and visual observation, each tissue sample was classified according to the stage (0, I, II, III) of atherosclerosis development (SAD). Then, strip samples considered as a membrane with the shape of rectangular parallelepiped were preconditioned and subjected to uniaxial tensile tests in longitudinal (n=27) and circumferential (n=4) direction. With experimental data obtained, the stress-strain characteristics were prepared. Furthermore, tensile strengths and related strains, stiffness coefficients and tangent modules of elasticity were computed. For a constitutive model of passive mechanical behavior of coronary arteries, values of material parameters were computed. The studies led to the following conclusions. Most importantly, the atherosclerotic changes affect all the mechanical properties of arterial walls. A progress of arteriosclerosis contributes to an increase of vascular stiffness. The highest values of the stiffness coefficients are obtained for the tissues in the advanced stage of the disease. We were also able to observe that gradual calcification, progression of atherosclerosis and degradation of collagen in the tissue caused a decrease of tensile strengths and related strains. Finally, a comparison made for the tissues with the advanced SAD showed that the tensile strengths and strains were much higher in the case of the samples with the circumferential orientation rather than those with the longitudinal one. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Attempts to obtain re-osseointegration following experimental peri-implantitis in dogs.

    PubMed

    Wetzel, A C; Vlassis, J; Caffesse, R G; Hämmerle, C H; Lang, N P

    1999-04-01

    The purpose of this study was to examine the healing potential and re-osseointegration in peri-implant infection defects adjacent to various implant surfaces. In 7 female Beagle dogs, a total of 41 titanium oral implants (ITI, Straumann, Waldenburg; Switzerland) with a sink depth of 6 mm (diameter 2.8 mm) were placed transmucosally. Four different surface configurations (TPS: titanium plasma sprayed (10); SLA: sand blasted and acid-etched (13); M: machined and smooth (11); TPS furc.: titanium plasma sprayed with coronally placed perforation to mimic a furcation (7) were distributed among the animals and locations. Following a healing period of 3 months, silk ligatures were placed and oral cleaning procedures abolished for 4 months to induce a vertical bone loss of about 40%. Following mechanical and chemical cleansing (chlorhexidine and metronidazole) and disinfection, the lesions were either sham operated (11) or subjected to a GTR procedure using ePTFE (30). After 6 months of healing the animals were killed and the jaws histologically evaluated. Six membranes were lost TPS: (1); SLA: (2); M: (2); TPS furc: (1) and 3 membranes exposed TPS: (1); M: (2) and excluded from further evaluation. Owing to the loss of 1 implant and infection of the membranes in the TPS furc group, this implant configuration was discarded from further analysis. For TPS surfaces, bone fill was 2.6 mm (73% of the distance from the bottom of the defect to the shoulder of the implant) sites with (4 GTR) and 0.33 mm (14%) for sites without membrane (2 controls). Re-osseointegration was 0.5 mm (14%) in the test group and 0.3 mm (14%) in the control. For SLA surfaces bone fill was 2.3 mm (83%) for sites with (7 GTR) and 0.41 mm (15%) for sites without membranes (4 controls). Re-osseointegration was 0.6 mm (20%) and 0.3 mm (11%) respectively. Corresponding values for M surfaces were 2.2 mm (62%) with 4 GTR) and 0.82 mm (31%) without membranes. Re-osseointegration was 0.07 mm (2%) and 0.19 mm (7

  2. Storming a Citadel: Mathematical Theory and Experimental Practice

    NASA Astrophysics Data System (ADS)

    Sichau, Christian

    2006-09-01

    Based upon a comparison of the viscosity experiments of James Clerk Maxwell (1831 1879) and Oskar Emil Meyer (1834 1909) in the 1860s, I argue that mathematical theory plays a significant role in both aspects of experimental practice, the design and construction of an experimental apparatus and the transformation of the observed experimental data into the value of a physical quantity. I argue further that Maxwell’s and Meyer’s evaluation of each other’s theoretical and experimental work depended significantly on the mathematical tools they employed in their theories.

  3. Experimental method for determination of bending and torsional rigidities of advanced composite laminates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Maeda, Takenori

    1995-11-01

    This paper presents an experimental method for the determination of the bending and torsional rigidities of advanced fiber composite laminates with the aid of laser holographic interferometry. The proposed method consists of a four-point bending test and a resonance test. The bending rigidity ratio (D{sub 12}/D{sub 22}) can be determined from the fringe patterns of the four-point bending test. The bending rigidities (D{sub 11} and D{sub 22}) and the torsional rigidity (D{sub 66}) are calculated from the natural frequencies of cantilever plates of the resonance test. The test specimens are carbon/epoxy cross-ply laminates. The adequacy of the experimental method ismore » confirmed by comparing the measured rigidities with the theoretical values obtained from classical lamination theory (CLT) by using the measured tensile properties. The results show that the present method can be used to evaluate the rigidities of orthotropic laminates with reasonably good accuracy.« less

  4. Experimentally determined stiffness and damping of an inherently compensated air squeeze-film damper

    NASA Technical Reports Server (NTRS)

    Cunningham, R. E.

    1975-01-01

    Values of damping and stiffness were determined experimentally for an externally pressurized, inherently compensated, compressible squeeze-film damper up to excitation frequencies of 36,000 cycles per minute. Experimental damping values were higher than theory predicted at low squeeze numbers and less than predicted at high squeeze numbers. Experimental values of air film stiffness were less than theory predicted at low squeeze numbers and much greater at higher squeeze numbers. Results also indicate sufficient damping to attenuate amplitudes and forces at the critical speed when using three dampers in the flexible support system of a small, lightweight turborotor.

  5. Fractal analysis and its impact factors on pore structure of artificial cores based on the images obtained using magnetic resonance imaging

    NASA Astrophysics Data System (ADS)

    Wang, Heming; Liu, Yu; Song, Yongchen; Zhao, Yuechao; Zhao, Jiafei; Wang, Dayong

    2012-11-01

    Pore structure is one of important factors affecting the properties of porous media, but it is difficult to describe the complexity of pore structure exactly. Fractal theory is an effective and available method for quantifying the complex and irregular pore structure. In this paper, the fractal dimension calculated by box-counting method based on fractal theory was applied to characterize the pore structure of artificial cores. The microstructure or pore distribution in the porous material was obtained using the nuclear magnetic resonance imaging (MRI). Three classical fractals and one sand packed bed model were selected as the experimental material to investigate the influence of box sizes, threshold value, and the image resolution when performing fractal analysis. To avoid the influence of box sizes, a sequence of divisors of the image was proposed and compared with other two algorithms (geometric sequence and arithmetic sequence) with its performance of partitioning the image completely and bringing the least fitted error. Threshold value selected manually and automatically showed that it plays an important role during the image binary processing and the minimum-error method can be used to obtain an appropriate or reasonable one. Images obtained under different pixel matrices in MRI were used to analyze the influence of image resolution. Higher image resolution can detect more quantity of pore structure and increase its irregularity. With benefits of those influence factors, fractal analysis on four kinds of artificial cores showed the fractal dimension can be used to distinguish the different kinds of artificial cores and the relationship between fractal dimension and porosity or permeability can be expressed by the model of D = a - bln(x + c).

  6. Experimental launcher facility - ELF-I: Design and operation

    NASA Astrophysics Data System (ADS)

    Deis, D. W.; Ross, D. P.

    1982-01-01

    In order to investigate the general area of ultra-high-current density, high-velocity sliding contacts as applied to electromagnetic launcher armatures, a small experimental launcher, ELF-I, has been developed, and preliminary experiments have been performed. The system uses a 36 kJ, 5 kV capacitor bank as a primary pulse power source. When used in conjunction with a 5-microhenry pulse conditioning coil, a 100-kA peak current and 10-ms-wide pulse is obtained. A three-station 150 kV flash X-ray system is operational for obtaining in-bore photographs of the projectiles. Experimental results obtained for both metal and plasma armatures at sliding velocities of up to 1 km/s are discussed with emphasis on armature-rail interactions.

  7. Numerical and experimental investigations for the evaluation of the wear coefficient of reverse total shoulder prostheses.

    PubMed

    Mattei, Lorenza; Di Puccio, Francesca; Joyce, Thomas J; Ciulli, Enrico

    2015-03-01

    In the present study, numerical and experimental wear investigations on reverse total shoulder arthroplasties (RTSAs) were combined in order to estimate specific wear coefficients, currently not available in the literature. A wear model previously developed by the authors for metal-on-plastic hip implants was adapted to RTSAs and applied in a double direction: firstly, to evaluate specific wear coefficients for RTSAs from experimental results and secondly, to predict wear distribution. In both cases, the Archard wear law (AR) and the wear law of UHMWPE (PE) were considered, assuming four different k functions. The results indicated that both the wear laws predict higher wear coefficients for RTSA with respect to hip implants, particularly the AR law, with k values higher than twofold the hip ones. Such differences can significantly affect predictive wear model results for RTSA, when non-specific wear coefficients are used. Moreover, the wear maps simulated with the two laws are markedly different, although providing the same wear volume. A higher wear depth (+51%) is obtained with the AR law, located at the dome of the cup, while with the PE law the most worn region is close to the edge. Taking advantage of the linear trend of experimental volume losses, the wear coefficients obtained with the AR law should be valid despite having neglected the geometry update in the model. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Experimental Investigations on the effect of Additive on the Tensile Properties of Fiber Glass Fabric Lamina

    NASA Astrophysics Data System (ADS)

    Nava Sai Divya, A.; Raghu Kumar, B., Dr; Lakshmi Narayana, G., Dr

    2017-09-01

    The main objective of this work is to investigate the effect of additives on tensile behaviour of fiber glass fabric at lamina level to explore an alternative skin material for the outer body of aerospace applications and machines. This experimental work investigates the effect of silica concentration in epoxy resin lapox L-12 on the tensile properties of glass fabric lamina of 4H-satin weave having 3.6 mm thickness. The lamina was prepared by using hand lay-up method and tests were conducted on it. Various tensile properties values obtained from experimentation were compared for four glass fiber lamina composites fabricated by adding the silica powder to resin bath. The effect of variations in silica concentration (0% SiO2, 5% SiO2, 10% SiO2 and 15% SiO2) on the tensile properties of prepared material revealed that maximum stiffness was obtained at 15% and yield strength at 10% SiO2 concentration in glass fiber lamina. Increasing the silica concentration beyond 10% had led to deterioration in the material properties. The experimentation that was carried out on test specimen was reasonably successful as the effect of silica powder as an additive in glass fiber lamina enhanced the mechanical properties up to certain limit. The underpinning microscopic behaviour at the source of these observations will be investigated in a follow up work.

  9. Application of D-optimal experimental design method to optimize the formulation of O/W cosmetic emulsions.

    PubMed

    Djuris, J; Vasiljevic, D; Jokic, S; Ibric, S

    2014-02-01

    This study investigates the application of D-optimal mixture experimental design in optimization of O/W cosmetic emulsions. Cetearyl glucoside was used as a natural, biodegradable non-ionic emulsifier in the relatively low concentration (1%), and the mixture of co-emulsifiers (stearic acid, cetyl alcohol, stearyl alcohol and glyceryl stearate) was used to stabilize the formulations. To determine the optimal composition of co-emulsifiers mixture, D-optimal mixture experimental design was used. Prepared emulsions were characterized with rheological measurements, centrifugation test, specific conductivity and pH value measurements. All prepared samples appeared as white and homogenous creams, except for one homogenous and viscous lotion co-stabilized by stearic acid alone. Centrifugation testing revealed some phase separation only in the case of sample co-stabilized using glyceryl stearate alone. The obtained pH values indicated that all samples expressed mild acid value acceptable for cosmetic preparations. Specific conductivity values are attributed to the multiple phases O/W emulsions with high percentages of fixed water. Results of the rheological measurements have shown that the investigated samples exhibited non-Newtonian thixotropic behaviour. To determine the influence of each of the co-emulsifiers on emulsions properties, the obtained results were evaluated by the means of statistical analysis (ANOVA test). On the basis of comparison of statistical parameters for each of the studied responses, mixture reduced quadratic model was selected over the linear model implying that interactions between co-emulsifiers play the significant role in overall influence of co-emulsifiers on emulsions properties. Glyceryl stearate was found to be the dominant co-emulsifier affecting emulsions properties. Interactions between the glyceryl stearate and other co-emulsifiers were also found to significantly influence emulsions properties. These findings are especially important

  10. Limitations in electrophysiological model development and validation caused by differences between simulations and experimental protocols.

    PubMed

    Carro, Jesús; Rodríguez-Matas, José F; Monasterio, Violeta; Pueyo, Esther

    2017-10-01

    Models of ion channel dynamics are usually built by fitting isolated cell experimental values of individual parameters while neglecting the interaction between them. Another shortcoming regards the estimation of ionic current conductances, which is often based on quantification of Action Potential (AP)-derived markers. Although this procedure reduces the uncertainty in the calculation of conductances, many studies evaluate electrophysiological AP-derived markers from single cell simulations, whereas experimental measurements are obtained from tissue preparations. In this work, we explore the limitations of these approaches to estimate ion channel dynamics and maximum current conductances and how they could be overcome by using multiscale simulations of experimental protocols. Four human ventricular cell models, namely ten Tusscher and Panfilov (2006), Grandi et al. (2010), O'Hara et al. (2011), and Carro et al. (2011), were used. Two problems involving scales from ion channels to tissue were investigated: 1) characterization of L-type calcium voltage-dependent inactivation I Ca,L ; 2) identification of major ionic conductance contributors to steady-state AP markers, including APD 90 , APD 75 , APD 50 , APD 25 , Triangulation and maximal and minimal values of V and dV/dt during the AP (V max , V min , dV/dt max , dV/dt min ). Our results show that: 1) I Ca,L inactivation characteristics differed significantly when calculated from model equations and from simulations reproducing the experimental protocols. 2) Large differences were found in the ionic currents contributors to APD 25 , Triangulation, V max , dV/dt max and dV/dt min between single cells and 1D-tissue. When proposing any new model formulation, or evaluating an existing model, consistency between simulated and experimental data should be verified considering all involved effects and scales. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Experimental Mapping and Benchmarking of Magnetic Field Codes on the LHD Ion Accelerator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chitarin, G.; University of Padova, Dept. of Management and Engineering, strad. S. Nicola, 36100 Vicenza; Agostinetti, P.

    2011-09-26

    For the validation of the numerical models used for the design of the Neutral Beam Test Facility for ITER in Padua [1], an experimental benchmark against a full-size device has been sought. The LHD BL2 injector [2] has been chosen as a first benchmark, because the BL2 Negative Ion Source and Beam Accelerator are geometrically similar to SPIDER, even though BL2 does not include current bars and ferromagnetic materials. A comprehensive 3D magnetic field model of the LHD BL2 device has been developed based on the same assumptions used for SPIDER. In parallel, a detailed experimental magnetic map of themore » BL2 device has been obtained using a suitably designed 3D adjustable structure for the fine positioning of the magnetic sensors inside 27 of the 770 beamlet apertures. The calculated values have been compared to the experimental data. The work has confirmed the quality of the numerical model, and has also provided useful information on the magnetic non-uniformities due to the edge effects and to the tolerance on permanent magnet remanence.« less

  12. Evaluation of assigned-value uncertainty for complex calibrator value assignment processes: a prealbumin example.

    PubMed

    Middleton, John; Vaks, Jeffrey E

    2007-04-01

    Errors of calibrator-assigned values lead to errors in the testing of patient samples. The ability to estimate the uncertainties of calibrator-assigned values and other variables minimizes errors in testing processes. International Organization of Standardization guidelines provide simple equations for the estimation of calibrator uncertainty with simple value-assignment processes, but other methods are needed to estimate uncertainty in complex processes. We estimated the assigned-value uncertainty with a Monte Carlo computer simulation of a complex value-assignment process, based on a formalized description of the process, with measurement parameters estimated experimentally. This method was applied to study uncertainty of a multilevel calibrator value assignment for a prealbumin immunoassay. The simulation results showed that the component of the uncertainty added by the process of value transfer from the reference material CRM470 to the calibrator is smaller than that of the reference material itself (<0.8% vs 3.7%). Varying the process parameters in the simulation model allowed for optimizing the process, while keeping the added uncertainty small. The patient result uncertainty caused by the calibrator uncertainty was also found to be small. This method of estimating uncertainty is a powerful tool that allows for estimation of calibrator uncertainty for optimization of various value assignment processes, with a reduced number of measurements and reagent costs, while satisfying the requirements to uncertainty. The new method expands and augments existing methods to allow estimation of uncertainty in complex processes.

  13. [The significance of low-frequency magnetotherapy for local treatment of burns. An experimental comparative approach (author's transl)].

    PubMed

    Sauer, H D; Rudy, D

    1980-02-01

    Under standardized experimental conditions 3rd degree burns were produced on the neck of 241 Wistar-rats. The process of wound-healing was documented by means of planimetric, histologic and microbiologic methods. In comparison to an untreated control-group the effectiveness of low-frequency magnetotherapy (system magnetodyn 5 by W. Krauss) as well as coagulation of necrosis according to Grob and autologous skin-transplantation were studied. The results obtained indicate that only early debridement of necrosis and subsequent autologous skin-grafting guarantees sufficient acceleration of wound healing. The low-frequency magnetotherapy according to Krauss showed no effect of therapeutic value. With the coagulation of necrosis, as described by Grob, a germfree status under the necrosis was obtained for nearly 2 weeks.

  14. Sentimental value and its influence on hedonic adaptation.

    PubMed

    Yang, Yang; Galak, Jeff

    2015-11-01

    Sentimental value is a highly prevalent, yet largely understudied phenomenon. We introduce the construct of sentimental value and investigate how and why sentimental value influences hedonic adaptation. Across 7 studies, we examine the antecedents of sentimental value and demonstrate its effect on hedonic adaptation using both naturally occurring and experimentally manipulated items with sentimental value. We further test the underlying process linking sentimental value and hedonic adaptation by showing that whereas feature-related utility decreases for all items with time, sentimental value typically does not, and that sentimental value moderates the influence of the decrement in feature-related utility on hedonic adaptation. Moreover, this moderating effect of sentimental value is driven by a shift in focus from features of the item to the associations that item possess. We conclude with a discussion of related phenomena and implications for individuals. (c) 2015 APA, all rights reserved).

  15. Maximal isometric muscle strength values obtained By hand-held dynamometry in children between 6 and 15 years of age.

    PubMed

    Escobar, Raul G; Munoz, Karin T; Dominguez, Angelica; Banados, Pamela; Bravo, Maria J

    2017-01-01

    In this study we aimed to determine the maximal isometric muscle strength of a healthy, normal-weight, pediatric population between 6 and 15 years of age using hand-held dynamometry to establish strength reference values. The secondary objective was determining the relationship between strength and anthropometric parameters. Four hundred normal-weight Chilean children, split into 10 age groups, separated by 1-year intervals, were evaluated. Each age group included between 35 and 55 children. The strength values increased with increasing age and weight, with a correlation of 0.83 for age and 0.82 for weight. The results were similar to those reported in previous studies regarding the relationships among strength, age, and anthropometric parameters, but the reported strength differed. These results provide normal strength parameters for healthy and normal-weight Chilean children between 6 and 15 years of age and highlight the relevance of ethnicity in defining reference values for muscle strength in a pediatric population. Muscle Nerve 55: 16-22, 2017. © 2016 Wiley Periodicals, Inc.

  16. A combined experimental and DFT study of a novel unsymmetrical azine 2-(4-methoxybenzylidene)-1-(1-(4-isobutylphenyl) ethylidene) hydrazine

    NASA Astrophysics Data System (ADS)

    Vijaya, P.; Sankaran, K. R.

    2015-03-01

    A novel unsymmetrical azine 2-(4-methoxybenzylidene)-1-(1-(4-isobutylphenyl) ethylidene) hydrazine (UA) was prepared and characterized by IR, 1H and 13C NMR spectral studies. A 2D - potential energy scan (PES) of p-isobutylacetophenone (IBAP) was the portal to the conformational analysis of UA by density functional theory (DFT) methods using 6-31G(d,p) basis set by Gaussian 03 program. The theoretical IR frequencies were found to be in good agreement with the experimental values. The IR frequencies of UA were analyzed by means of Potential energy Distribution (PED %) calculation using Vibrational Energy Distribution Analysis (VEDA 4) program. The experimental NMR chemical shift values of UA were compared with the theoretical values obtained by DFT method. Nonlinear optical behavior of the unsymmetrical azine is also examined by the theoretically predicted values of dipole moment (μ), polarizability (α0) and first hyperpolarizability (βtot). Stability of the UA molecule has been analyzed using NBO analysis. The electrochemistry of UA studied experimentally by cyclic voltammetry is complemented by the computational analysis of the anionic form of the molecule UA. The determination of various global and local reactivity descriptors in the context of chemical reactivity is also performed and the electrophilicity at the vital atomic sites in UA is revealed. Bader's Atoms in molecules (AIM) theory of UA indicated the presence of intramolecular hydrogen bonding in the molecule. The molecular electrostatic potential (MEP) and HOMO-LUMO orbital analysis are also performed for the molecule UA.

  17. A combined experimental and DFT study of a novel unsymmetrical azine 2-(4-methoxybenzylidene)-1-(1-(4-isobutylphenyl) ethylidene) hydrazine.

    PubMed

    Vijaya, P; Sankaran, K R

    2015-03-05

    A novel unsymmetrical azine 2-(4-methoxybenzylidene)-1-(1-(4-isobutylphenyl) ethylidene) hydrazine (UA) was prepared and characterized by IR, (1)H and (13)C NMR spectral studies. A 2D - potential energy scan (PES) of p-isobutylacetophenone (IBAP) was the portal to the conformational analysis of UA by density functional theory (DFT) methods using 6-31G(d,p) basis set by Gaussian 03 program. The theoretical IR frequencies were found to be in good agreement with the experimental values. The IR frequencies of UA were analyzed by means of Potential energy Distribution (PED %) calculation using Vibrational Energy Distribution Analysis (VEDA 4) program. The experimental NMR chemical shift values of UA were compared with the theoretical values obtained by DFT method. Nonlinear optical behavior of the unsymmetrical azine is also examined by the theoretically predicted values of dipole moment (μ), polarizability (α0) and first hyperpolarizability (βtot). Stability of the UA molecule has been analyzed using NBO analysis. The electrochemistry of UA studied experimentally by cyclic voltammetry is complemented by the computational analysis of the anionic form of the molecule UA. The determination of various global and local reactivity descriptors in the context of chemical reactivity is also performed and the electrophilicity at the vital atomic sites in UA is revealed. Bader's Atoms in molecules (AIM) theory of UA indicated the presence of intramolecular hydrogen bonding in the molecule. The molecular electrostatic potential (MEP) and HOMO-LUMO orbital analysis are also performed for the molecule UA. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. The value of duck-embryo vaccine and high-egg-passage Flury vaccine in experimental rabies infection in guinea-pigs

    PubMed Central

    Veeraraghavan, N.; Subrahmanyan, T. P.

    1963-01-01

    The authors have compared the value of multiple doses of duck-embryo and HEP Flury vaccine with that of pooled 5% sheep-brain vaccine in experimental rabies infection in guinea-pigs. They found that the duck-embryo vaccine given in a dosage corresponding to 14 ml of 10% vaccine (the dosage recommended for human treatment), either alone or with antirabies serum, gave no protection and that, even when administered in a dosage corresponding to 140 ml of 5% pooled vaccine, both the duck-embryo and the HEP Flury vaccines, whether alone or with serum, conferred little protection. Pooled phenolized vaccine under identical conditions gave good results. The immunogenicity of duck-embryo and HEP Flury vaccines, given before infection, was also inferior to that of pooled vaccine; and the duck-embryo vaccine was found to be a poorer antigen than the pooled vaccine in mouse potency tests. The authors conclude that the dosage of duck-embryo vaccine recommended for human treatment is inadequate and that the HEP Flury vaccine in its present form is unsuitable for post-infection treatment. PMID:14065070

  19. Self-Esteem Depends on the Beholder: Effects of a Subtle Social Value Cue

    PubMed Central

    Weisbuch, Max; Sinclair, Stacey A.; Skorinko, Jeanine L.; Eccleston, Collette P.

    2009-01-01

    The idea that self-esteem functions as a gauge or “sociometer” of social value (Leary & Baumeister, 2000) is supported by research on direct social feedback. To examine if the sociometer model is relevant to more subtle social value cues, the implicit self-esteem of women was assessed a week after an interaction with an experimenter. Consistent with the sociometer model, Week 2 self-esteem depended on a subtle social value cue encountered during Week 1. When the Week 1 experimenter wore a t-shirt celebrating larger bodies (i.e., “everyBODY is beautiful”), heavier women had higher self-esteem than lighter women in Week 2. As hypothesized, this effect was relationship-specific, occurring only when the same experimenter administered Week 1 and 2 sessions. PMID:20047001

  20. New measurements of W-values for protons and alpha particles.

    PubMed

    Giesen, U; Beck, J

    2014-10-01

    The increasing importance of ion beams in cancer therapy and the lack of experimental data for W-values for protons and heavy ions in air require new measurements. A new experimental set-up was developed at PTB and consistent measurements of W-values in argon, nitrogen and air for protons and alpha particles with energies from 0.7 to 3.5 MeV u(-1) at PTB, and for carbon ions between 3.6 and 7.0 MeV u(-1) at GSI were carried out. This publication concentrates on the measurements with protons and alpha particles at PTB. The experimental methods and the determination of corrections for recombination effects, beam-induced background radiation and additional effects are presented. © The Author 2013. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  1. Optimal atomic structure of amorphous silicon obtained from density functional theory calculations

    NASA Astrophysics Data System (ADS)

    Pedersen, Andreas; Pizzagalli, Laurent; Jónsson, Hannes

    2017-06-01

    Atomic structure of amorphous silicon consistent with several reported experimental measurements has been obtained from annealing simulations using electron density functional theory calculations and a systematic removal of weakly bound atoms. The excess energy and density with respect to the crystal are well reproduced in addition to radial distribution function, angular distribution functions, and vibrational density of states. No atom in the optimal configuration is locally in a crystalline environment as deduced by ring analysis and common neighbor analysis, but coordination defects are present at a level of 1%-2%. The simulated samples provide structural models of this archetypal disordered covalent material without preconceived notion of the atomic ordering or fitting to experimental data.

  2. Optimization of Regression Models of Experimental Data Using Confirmation Points

    NASA Technical Reports Server (NTRS)

    Ulbrich, N.

    2010-01-01

    A new search metric is discussed that may be used to better assess the predictive capability of different math term combinations during the optimization of a regression model of experimental data. The new search metric can be determined for each tested math term combination if the given experimental data set is split into two subsets. The first subset consists of data points that are only used to determine the coefficients of the regression model. The second subset consists of confirmation points that are exclusively used to test the regression model. The new search metric value is assigned after comparing two values that describe the quality of the fit of each subset. The first value is the standard deviation of the PRESS residuals of the data points. The second value is the standard deviation of the response residuals of the confirmation points. The greater of the two values is used as the new search metric value. This choice guarantees that both standard deviations are always less or equal to the value that is used during the optimization. Experimental data from the calibration of a wind tunnel strain-gage balance is used to illustrate the application of the new search metric. The new search metric ultimately generates an optimized regression model that was already tested at regression model independent confirmation points before it is ever used to predict an unknown response from a set of regressors.

  3. The Fraser Experimental Forest, Colorado

    Treesearch

    Robert R. Alexander; Ross K. Watkins

    1977-01-01

    This report provides a general overview of work done on the Fraser Experimental Forest. It replaces Station Paper No.8, published in 1952 and revised by L. D. Love in 1960. Included are descriptions of physical features and resource values, and highlights of past and current research programs.

  4. Theoretical and experimental indicators of falls during pregnancy as assessed by postural perturbations.

    PubMed

    Ersal, Tulga; McCrory, Jean L; Sienko, Kathleen H

    2014-01-01

    Throughout pregnancy, women experience physical, physiological, and hormonal alterations that are often accompanied by decreased postural control. According to one study, nearly 27% of pregnant women fell while pregnant. This study had two objectives: (1) to characterize the postural responses of pregnant fallers, nonfallers, and controls to surface perturbations, and (2) to develop a mathematical model to gain insights into the postural control strategies of each group. This retrospective analysis used experimental data obtained from 15 women with a fall history during pregnancy, 14 women without a fall history during pregnancy, and 40 nonpregnant controls. Small, medium, and large translational support surface perturbations in the anterior and posterior directions were performed during the pregnant participants' second and third trimesters. A two-segmented mathematical model of bipedal stance was developed and parameterized, and optimization tools were used to identify ankle and hip stiffness, viscosity, and the feedback time delay by searching for the best fits to experimental COP data. The peak differences between the center of pressure and center of gravity (COP-COG) values were significantly smaller for the pregnant fallers compared with the pregnant nonfallers and controls (p<0.01). Perturbation magnitude was a significant factor (p<0.01), but perturbation direction was not (p=0.24). Model fits were obtained with a mean goodness of fit value of R(2)=0.92. Theoretical results indicated that pregnant nonfallers had higher ankle stiffness compared with the pregnant fallers and the controls, which suggests that ankle stiffness itself may be the dominant reason for the different dynamic response characteristics (e.g., peak COP-COG) observed. We conclude that increasing ankle stiffness could be an important strategy to prevent falling by pregnant women. Copyright © 2013 Elsevier B.V. All rights reserved.

  5. A precise and accurate acupoint location obtained on the face using consistency matrix pointwise fusion method.

    PubMed

    Yanq, Xuming; Ye, Yijun; Xia, Yong; Wei, Xuanzhong; Wang, Zheyu; Ni, Hongmei; Zhu, Ying; Xu, Lingyu

    2015-02-01

    To develop a more precise and accurate method, and identified a procedure to measure whether an acupoint had been correctly located. On the face, we used an acupoint location from different acupuncture experts and obtained the most precise and accurate values of acupoint location based on the consistency information fusion algorithm, through a virtual simulation of the facial orientation coordinate system. Because of inconsistencies in each acupuncture expert's original data, the system error the general weight calculation. First, we corrected each expert of acupoint location system error itself, to obtain a rational quantification for each expert of acupuncture and moxibustion acupoint location consistent support degree, to obtain pointwise variable precision fusion results, to put every expert's acupuncture acupoint location fusion error enhanced to pointwise variable precision. Then, we more effectively used the measured characteristics of different acupuncture expert's acupoint location, to improve the measurement information utilization efficiency and acupuncture acupoint location precision and accuracy. Based on using the consistency matrix pointwise fusion method on the acupuncture experts' acupoint location values, each expert's acupoint location information could be calculated, and the most precise and accurate values of each expert's acupoint location could be obtained.

  6. Automatic sleep stage classification of single-channel EEG by using complex-valued convolutional neural network.

    PubMed

    Zhang, Junming; Wu, Yan

    2018-03-28

    Many systems are developed for automatic sleep stage classification. However, nearly all models are based on handcrafted features. Because of the large feature space, there are so many features that feature selection should be used. Meanwhile, designing handcrafted features is a difficult and time-consuming task because the feature designing needs domain knowledge of experienced experts. Results vary when different sets of features are chosen to identify sleep stages. Additionally, many features that we may be unaware of exist. However, these features may be important for sleep stage classification. Therefore, a new sleep stage classification system, which is based on the complex-valued convolutional neural network (CCNN), is proposed in this study. Unlike the existing sleep stage methods, our method can automatically extract features from raw electroencephalography data and then classify sleep stage based on the learned features. Additionally, we also prove that the decision boundaries for the real and imaginary parts of a complex-valued convolutional neuron intersect orthogonally. The classification performances of handcrafted features are compared with those of learned features via CCNN. Experimental results show that the proposed method is comparable to the existing methods. CCNN obtains a better classification performance and considerably faster convergence speed than convolutional neural network. Experimental results also show that the proposed method is a useful decision-support tool for automatic sleep stage classification.

  7. First direct determination of the 48Ca double-β decay Q value

    NASA Astrophysics Data System (ADS)

    Bustabad, S.; Bollen, G.; Brodeur, M.; Lincoln, D. L.; Novario, S. J.; Redshaw, M.; Ringle, R.; Schwarz, S.; Valverde, A. A.

    2013-08-01

    The low-energy beam and ion trap Penning trap mass spectrometer was used for an improved determination of the 48Ca double-β decay Q value: Qββ=4268.121(79)keV. The new value is 1.2 keV greater than the value in the 2012 atomic mass evaluation [Chin. Phys. CCPCHCQ1674-113710.1088/1674-1137/36/12/003 36, 1603 (2012)], a shift of three σ, and is a factor of 5 more precise. Accurate knowledge of this Q value is important for experimental searches to observe neutrinoless double-β decay (0νββ) in 48Ca and is essential for extracting the effective mass of the electron neutrino if the 48Ca half-life of 0νββ was experimentally determined.

  8. Analytical and experimental study of the vibration of bonded beams with a lap joint

    NASA Technical Reports Server (NTRS)

    Rao, M. D.; Crocker, M. J.

    1990-01-01

    A theoretical model to study the flexural vibration of a bonded lap joint system is described in this paper. First, equations of motion at the joint region are derived using a differential element approach. The transverse displacements of the upper and lower beam are considered to be different. The adhesive is assumed to be linearly viscoelastic and the widely used Kelvin-Voight model is used to represent the viscoelastic behavior of the adhesive. The shear force at the interface between the adhesive and the beam is obtained from the simple bending motion equations of the two beams. The resulting equations of motion are combined with the equations of transverse vibration of the beams in the unjointed regions. These are later solved as a boundary value problem to obtain the eigenvalues and eigenvectors of the system. The model can be used to predict the natural frequencies, modal damping ratios, and mode shapes of the system for free vibration. Good agreement between numerical and experimental results was obtained for a system of graphite epoxy beams lap-jointed by an epoxy adhesive.

  9. Experimental analysis of refrigerants flow boiling inside small sized microfin tubes

    NASA Astrophysics Data System (ADS)

    Diani, Andrea; Rossetto, Luisa

    2017-07-01

    The refrigerant charge reduction is one of the most challenging issues that the scientific community has to cope to reduce the anthropic global warming. Recently, mini microfin tubes have been matter of research, since they can reach better thermal performance in small domains, leading to a further refrigerant charge reduction. This paper presents experimental results about R134a flow boiling inside a microfin tube having an internal diameter at the fin tip of 2.4 mm. The mass flux was varied between 375 and 940 kg m-2 s-1, heat flux from 10 to 50 kW m-2, vapor quality from 0.10 to 0.99. The saturation temperature at the inlet of the test section was kept constant and equal to 30 °C. R134a thermal and fluid dynamic performances are presented and compared against those obtained with R1234ze(E) and R1234yf and against values obtained during R134a flow boiling inside a 3.4 mm ID microfin tube.

  10. A More Accurate and Efficient Technique Developed for Using Computational Methods to Obtain Helical Traveling-Wave Tube Interaction Impedance

    NASA Technical Reports Server (NTRS)

    Kory, Carol L.

    1999-01-01

    The phenomenal growth of commercial communications has created a great demand for traveling-wave tube (TWT) amplifiers. Although the helix slow-wave circuit remains the mainstay of the TWT industry because of its exceptionally wide bandwidth, until recently it has been impossible to accurately analyze a helical TWT using its exact dimensions because of the complexity of its geometrical structure. For the first time, an accurate three-dimensional helical model was developed that allows accurate prediction of TWT cold-test characteristics including operating frequency, interaction impedance, and attenuation. This computational model, which was developed at the NASA Lewis Research Center, allows TWT designers to obtain a more accurate value of interaction impedance than is possible using experimental methods. Obtaining helical slow-wave circuit interaction impedance is an important part of the design process for a TWT because it is related to the gain and efficiency of the tube. This impedance cannot be measured directly; thus, conventional methods involve perturbing a helical circuit with a cylindrical dielectric rod placed on the central axis of the circuit and obtaining the difference in resonant frequency between the perturbed and unperturbed circuits. A mathematical relationship has been derived between this frequency difference and the interaction impedance (ref. 1). However, because of the complex configuration of the helical circuit, deriving this relationship involves several approximations. In addition, this experimental procedure is time-consuming and expensive, but until recently it was widely accepted as the most accurate means of determining interaction impedance. The advent of an accurate three-dimensional helical circuit model (ref. 2) made it possible for Lewis researchers to fully investigate standard approximations made in deriving the relationship between measured perturbation data and interaction impedance. The most prominent approximations made

  11. A study of the b-quark fragmentation function with the DELPHI detector at LEP I and an averaged distribution obtained at the Z Pole

    NASA Astrophysics Data System (ADS)

    Abdallah, J.; Abreu, P.; Adam, W.; Adzic, P.; Albrecht, T.; Alemany-Fernandez, R.; Allmendinger, T.; Allport, P. P.; Amaldi, U.; Amapane, N.; Amato, S.; Anashkin, E.; Andreazza, A.; Andringa, S.; Anjos, N.; Antilogus, P.; Apel, W.-D.; Arnoud, Y.; Ask, S.; Asman, B.; Augustin, J. E.; Augustinus, A.; Baillon, P.; Ballestrero, A.; Bambade, P.; Barbier, R.; Bardin, D.; Barker, G. J.; Baroncelli, A.; Battaglia, M.; Baubillier, M.; Becks, K.-H.; Begalli, M.; Behrmann, A.; Ben-Haim, E.; Benekos, N.; Benvenuti, A.; Berat, C.; Berggren, M.; Bertrand, D.; Besancon, M.; Besson, N.; Bloch, D.; Blom, M.; Bluj, M.; Bonesini, M.; Boonekamp, M.; Booth, P. S. L.; Borisov, G.; Botner, O.; Bouquet, B.; Bowcock, T. J. V.; Boyko, I.; Bracko, M.; Brenner, R.; Brodet, E.; Bruckman, P.; Brunet, J. M.; Buschbeck, B.; Buschmann, P.; Calvi, M.; Camporesi, T.; Canale, V.; Carena, F.; Castro, N.; Cavallo, F.; Chapkin, M.; Charpentier, Ph.; Checchia, P.; Chierici, R.; Chliapnikov, P.; Chudoba, J.; Chung, S. U.; Cieslik, K.; Collins, P.; Contri, R.; Cosme, G.; Cossutti, F.; Costa, M. J.; Crennell, D.; Cuevas, J.; D'Hondt, J.; da Silva, T.; Da Silva, W.; Della Ricca, G.; De Angelis, A.; De Boer, W.; De Clercq, C.; De Lotto, B.; De Maria, N.; De Min, A.; de Paula, L.; Di Ciaccio, L.; Di Simone, A.; Doroba, K.; Drees, J.; Eigen, G.; Ekelof, T.; Ellert, M.; Elsing, M.; Espirito Santo, M. C.; Fanourakis, G.; Fassouliotis, D.; Feindt, M.; Fernandez, J.; Ferrer, A.; Ferro, F.; Flagmeyer, U.; Foeth, H.; Fokitis, E.; Fulda-Quenzer, F.; Fuster, J.; Gandelman, M.; Garcia, C.; Gavillet, Ph.; Gazis, E.; Gokieli, R.; Golob, B.; Gomez-Ceballos, G.; Goncalves, P.; Graziani, E.; Grosdidier, G.; Grzelak, K.; Guy, J.; Haag, C.; Hallgren, A.; Hamacher, K.; Hamilton, K.; Haug, S.; Hauler, F.; Hedberg, V.; Hennecke, M.; Hoffman, J.; Holmgren, S.-O.; Holt, P. J.; Houlden, M. A.; Jackson, J. N.; Jarlskog, G.; Jarry, P.; Jeans, D.; Johansson, E. K.; Jonsson, P.; Joram, C.; Jungermann, L.; Kapusta, F.; Katsanevas, S.; Katsoufis, E.; Kernel, G.; Kersevan, B. P.; Kerzel, U.; King, B. T.; Kjaer, N. J.; Kluit, P.; Kokkinias, P.; Kourkoumelis, C.; Kouznetsov, O.; Krumstein, Z.; Kucharczyk, M.; Lamsa, J.; Leder, G.; Ledroit, F.; Leinonen, L.; Leitner, R.; Lemonne, J.; Lepeltier, V.; Lesiak, T.; Liebig, W.; Liko, D.; Lipniacka, A.; Lopes, J. H.; Lopez, J. M.; Loukas, D.; Lutz, P.; Lyons, L.; MacNaughton, J.; Malek, A.; Maltezos, S.; Mandl, F.; Marco, J.; Marco, R.; Marechal, B.; Margoni, M.; Marin, J.-C.; Mariotti, C.; Markou, A.; Martinez-Rivero, C.; Masik, J.; Mastroyiannopoulos, N.; Matorras, F.; Matteuzzi, C.; Mazzucato, F.; Mazzucato, M.; Mc Nulty, R.; Meroni, C.; Migliore, E.; Mitaroff, W.; Mjoernmark, U.; Moa, T.; Moch, M.; Moenig, K.; Monge, R.; Montenegro, J.; Moraes, D.; Moreno, S.; Morettini, P.; Mueller, U.; Muenich, K.; Mulders, M.; Mundim, L.; Murray, W.; Muryn, B.; Myatt, G.; Myklebust, T.; Nassiakou, M.; Navarria, F.; Nawrocki, K.; Nemecek, S.; Nicolaidou, R.; Nikolenko, M.; Oblakowska-Mucha, A.; Obraztsov, V.; Olshevski, A.; Onofre, A.; Orava, R.; Osterberg, K.; Ouraou, A.; Oyanguren, A.; Paganoni, M.; Paiano, S.; Palacios, J. P.; Palka, H.; Papadopoulou, Th. D.; Pape, L.; Parkes, C.; Parodi, F.; Parzefall, U.; Passeri, A.; Passon, O.; Peralta, L.; Perepelitsa, V.; Perrotta, A.; Petrolini, A.; Piedra, J.; Pieri, L.; Pierre, F.; Pimenta, M.; Piotto, E.; Podobnik, T.; Poireau, V.; Pol, M. E.; Polok, G.; Pozdniakov, V.; Pukhaeva, N.; Pullia, A.; Radojicic, D.; Rebecchi, P.; Rehn, J.; Reid, D.; Reinhardt, R.; Renton, P.; Richard, F.; Ridky, J.; Rivero, M.; Rodriguez, D.; Romero, A.; Ronchese, P.; Roudeau, P.; Rovelli, T.; Ruhlmann-Kleider, V.; Ryabtchikov, D.; Sadovsky, A.; Salmi, L.; Salt, J.; Sander, C.; Savoy-Navarro, A.; Schwickerath, U.; Sekulin, R.; Siebel, M.; Sisakian, A.; Smadja, G.; Smirnova, O.; Sokolov, A.; Sopczak, A.; Sosnowski, R.; Spassov, T.; Stanitzki, M.; Stocchi, A.; Strauss, J.; Stugu, B.; Szczekowski, M.; Szeptycka, M.; Szumlak, T.; Tabarelli, T.; Tegenfeldt, F.; Timmermans, J.; Tkatchev, L.; Tobin, M.; Todorovova, S.; Tome, B.; Tonazzo, A.; Tortosa, P.; Travnicek, P.; Treille, D.; Tristram, G.; Trochimczuk, M.; Troncon, C.; Turluer, M.-L.; Tyapkin, I. A.; Tyapkin, P.; Tzamarias, S.; Uvarov, V.; Valenti, G.; Van Dam, P.; Van Eldik, J.; van Remortel, N.; Van Vulpen, I.; Vegni, G.; Veloso, F.; Venus, W.; Verdier, P.; Verzi, V.; Vilanova, D.; Vitale, L.; Vrba, V.; Wahlen, H.; Washbrook, A. J.; Weiser, C.; Wicke, D.; Wickens, J.; Wilkinson, G.; Winter, M.; Witek, M.; Yushchenko, O.; Zalewska, A.; Zalewski, P.; Zavrtanik, D.; Zhuravlov, V.; Zimin, N. I.; Zintchenko, A.; Zupan, M.

    2011-02-01

    The nature of b-quark jet hadronisation has been investigated using data taken at the Z peak by the DELPHI detector at LEP. Two complementary methods are used to reconstruct the energy of weakly decaying b-hadrons, EB^{weak}. The average value of x^{weak}B = EB^{weak}/E_{beam} is measured to be 0.699±0.011. The resulting x^{weak}B distribution is then analysed in the framework of two choices for the perturbative contribution (parton shower and Next to Leading Log QCD calculation) in order to extract measurements of the non-perturbative contribution to be used in studies of b-hadron production in other experimental environments than LEP. In the parton shower framework, data favour the Lund model ansatz and corresponding values of its parameters have been determined within PYTHIA 6.156 from DELPHI data: a= 1.84^{+0.23}_{-0.21}quadandquad b=0.642^{+0.073}_{-0.063} GeV^{-2}, with a correlation factor ρ=92.2%. Combining the data on the b-quark fragmentation distributions with those obtained at the Z peak by ALEPH, OPAL and SLD, the average value of x^{weak}B is found to be 0.7092±0.0025 and the non-perturbative fragmentation component is extracted. Using the combined distribution, a better determination of the Lund parameters is also obtained: a= 1.48^{+0.11}_{-0.10}quadandquad b=0.509^{+0.024}_{-0.023} GeV^{-2}, with a correlation factor ρ=92.6%.

  12. Case-Study of the High School Student's Family Values Formation

    ERIC Educational Resources Information Center

    Valeeva, Roza A.; Korolyeva, Natalya E.; Sakhapova, Farida Kh.

    2016-01-01

    The aim of the research is the theoretical justification and experimental verification of content, complex forms and methods to ensure effective development of the high school students' family values formation. 93 lyceum students from Kazan took part in the experiment. To study students' family values we have applied method of studying personality…

  13. Prediction of glutathionylation sites in proteins using minimal sequence information and their experimental validation.

    PubMed

    Pal, Debojyoti; Sharma, Deepak; Kumar, Mukesh; Sandur, Santosh K

    2016-09-01

    S-glutathionylation of proteins plays an important role in various biological processes and is known to be protective modification during oxidative stress. Since, experimental detection of S-glutathionylation is labor intensive and time consuming, bioinformatics based approach is a viable alternative. Available methods require relatively longer sequence information, which may prevent prediction if sequence information is incomplete. Here, we present a model to predict glutathionylation sites from pentapeptide sequences. It is based upon differential association of amino acids with glutathionylated and non-glutathionylated cysteines from a database of experimentally verified sequences. This data was used to calculate position dependent F-scores, which measure how a particular amino acid at a particular position may affect the likelihood of glutathionylation event. Glutathionylation-score (G-score), indicating propensity of a sequence to undergo glutathionylation, was calculated using position-dependent F-scores for each amino-acid. Cut-off values were used for prediction. Our model returned an accuracy of 58% with Matthew's correlation-coefficient (MCC) value of 0.165. On an independent dataset, our model outperformed the currently available model, in spite of needing much less sequence information. Pentapeptide motifs having high abundance among glutathionylated proteins were identified. A list of potential glutathionylation hotspot sequences were obtained by assigning G-scores and subsequent Protein-BLAST analysis revealed a total of 254 putative glutathionable proteins, a number of which were already known to be glutathionylated. Our model predicted glutathionylation sites in 93.93% of experimentally verified glutathionylated proteins. Outcome of this study may assist in discovering novel glutathionylation sites and finding candidate proteins for glutathionylation.

  14. High-capacity adsorption of Cr(VI) from aqueous solution using a hierarchical porous carbon obtained from pig bone.

    PubMed

    Wei, Shaochen; Li, Dongtian; Huang, Zhe; Huang, Yaqin; Wang, Feng

    2013-04-01

    A hierarchical porous carbon obtained from pig bone (HPC) was utilized as the adsorbent for removal of Cr(VI) from aqueous solution. The effects of solution pH value, concentration of Cr(VI), and adsorption temperature on the removal of Cr(VI) were investigated. The experimental data of the HPC fitted well with the Langmuir isotherm and its adsorption kinetic followed pseudo-second order model. Compared with a commercial activated carbon adsorbent (Norit CGP), the HPC showed an high adsorption capability for Cr(VI). The maximum Cr(VI) adsorption capacity of the HPC was 398.40 mg/g at pH 2. It is found that a part of the Cr(VI) was reduced to Cr(III) on the adsorbent surface from desorption experiment data. The regeneration showed adsorption capacity of the HPC can still achieve 92.70 mg/g even after fifth adsorption cycle. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Experimental characterization of the AFIT neutron facility. Master's thesis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lessard, O.J.

    1993-09-01

    AFIT's Neutron Facility was characterized for room-return neutrons using a (252)Cf source and a Bonner sphere spectrometer with three experimental models, the shadow shield, the Eisenhauer, Schwartz, and Johnson (ESJ), and the polynomial models. The free-field fluences at one meter from the ESJ and polynomial models were compared to the equivalent value from the accepted experimental shadow shield model to determine the suitability of the models in the AFIT facility. The polynomial model behaved erratically, as expected, while the ESJ model compared to within 4.8% of the shadow shield model results for the four Bonner sphere calibration. The ratio ofmore » total fluence to free-field fluence at one meter for the ESJ model was then compared to the equivalent ratio obtained by a Monte Cario Neutron-Photon transport code (MCNP), an accepted computational model. The ESJ model compared to within 6.2% of the MCNP results. AFIT's fluence ratios were compared to equivalent ratios reported by three other neutron facilities which verified that AFIT's results fit previously published trends based on room volumes. The ESJ model appeared adequate for health physics applications and was chosen was chosen for calibration of the AFIT facility. Neutron Detector, Bonner Sphere, Neutron Dosimetry, Room Characterization.« less

  16. Attenuation of the Atmospheric Migration Ability of Polychlorinated Naphthalenes (PCN-2) Based on Three-dimensional QSAR Models with Full Factor Experimental Design.

    PubMed

    Gu, Wenwen; Chen, Ying; Li, Yu

    2017-08-01

    Based on the experimental subcooled liquid vapor pressures (P L ) of 17 polychlorinated naphthalene (PCN) congeners, one type of three-dimensional quantitative structure-activity relationship (3D-QSAR) models, comparative molecular similarity indices analysis (CoMSIA), was constructed with Sybyl software. Full factor experimental design was used to obtain the final regulation scheme for PCN, and then carry out modification of PCN-2 to significantly lower its P L . The contour maps of CoMSIA model showed that the migration ability of PCN decreases when the Cl atoms at the 2-, 3-, 4-, 5-, 6-, 7- and 8-positions of PCNs are replaced by electropositive groups. After modification of PCN-2, 12 types of new modified PCN-2 compounds were obtained with lnP L values two orders of magnitude lower than that of PCN-2. In addition, there are significant differences between the calculated total energies and energy gaps of the new modified compounds and those of PCN-2.

  17. Full characterization of modular values for finite-dimensional systems

    NASA Astrophysics Data System (ADS)

    Ho, Le Bin; Imoto, Nobuyuki

    2016-06-01

    Kedem and Vaidman obtained a relationship between the spin-operator modular value and its weak value for specific coupling strengths [14]. Here we give a general expression for the modular value in the n-dimensional Hilbert space using the weak values up to (n - 1)th order of an arbitrary observable for any coupling strength, assuming non-degenerated eigenvalues. For two-dimensional case, it shows a linear relationship between the weak value and the modular value. We also relate the modular value of the sum of observables to the weak value of their product.

  18. Experimental observation of the shift and width of the aluminium K absorption edge in laser shock-compressed plasmas

    NASA Astrophysics Data System (ADS)

    Hall, T. A.; Al-Kuzee, J.; Benuzzi, A.; Koenig, M.; Krishnan, J.; Grandjouan, N.; Batani, D.; Bossi, S.; Nicolella, S.

    1998-03-01

    Experimental measurements of the shift and width of the aluminium K-absorption edge in laser shock-compressed plasma is presented. The spectrometer used in these experiments allows an accurate wavelength calibration and fiduciary and hence provides precise measurements of both the shift and the width of the absorption edge. Results have been obtained for compressions up to approximately ×2 and temperatures up to about 1.5 eV. The values of shift and width are compared with a new model with which there is very good agreement.

  19. Experimental Investigation of Droplet Evaporation of Water with Ground Admixtures while Motion in a Flame of Liquid Fuel

    NASA Astrophysics Data System (ADS)

    Dmitriyenko, Margarita A.; Nyashina, Galina S.; Zhdanova, Alena O.; Vysokomornaya, Olga V.

    2016-02-01

    The evaporation features for the atomized flow of suspension on the base of water with ground admixtures in an area of high-temperature combustion products of liquid flammable substance (acetone) were investigated experimentally by the optical methods of gas flow diagnostic and the high-speed video recording. The scales of influence of clay and silt concentration in droplets of atomized flow on the intensity of its evaporation were determined. The approximation dependences describing a decrease in typical size of suspension droplets at various values of ground admixtures were obtained.

  20. [Reference values of energy for the Venezuelan population].

    PubMed

    Landaeta-Jiménez, Maritza; Aliaga, Carla; Sifontes, Yaritza; Vásquez, Maura; Ramírez, Guillermo; Falque Madrid, Luís; Herrera, Marianella; María Reyes, Ana; Emilia, Elzakem; Herrera, Ctor; Bernal, Jennifer

    2013-12-01

    The project of updating the Venezuelan energy reference values respond to the recommendations made by an FAO experts committee, several decades ago for the countries assuming this work. Because of the dramatic changes experienced globally regarding energy intake/expenditure and particularly variations on the Venezuelan nutritional scenario with the presence of "the double burden of malnutrition" it a review of Energy Reference Values (VRE) from a more integral approach is pertinent. This report follows the methodology proposed by FAO/WHO/UNU 2004 experts committee and energy reference values were established by group of age and gender, also average energy values for Venezuelan population were obtained. For calculation of these requirements, the energy expenditure was included by taking into account Basal Metabolic Rate and physical activity level for some specific groups. The score average values updated in 2012 of 2.200 kcal/dia reported to be lower than those of 2000 at all ages for masculine gender except for the 16-17 age group and for feminine gender just until ages 10-12 years and from there are slightly above the values obtained in 2000.

  1. Systemic treatment with resveratrol and/or curcumin reduces the progression of experimental periodontitis in rats.

    PubMed

    Corrêa, M G; Pires, P R; Ribeiro, F V; Pimentel, S Z; Casarin, R C V; Cirano, F R; Tenenbaum, H T; Casati, M Z

    2017-04-01

    Periodontitis is a chronic inflammatory disease of periodontal tissues that leads to the destruction of bone and other connective tissues. Resveratrol and curcumin are plant-derived substances with biological properties that may have immunomodulatory properties. This study investigated the effect of continuous administration of resveratrol and curcumin and the association of resveratrol and curcumin on the progression of experimental periodontitis in rats. Forty Wistar rats were assigned randomly to the following groups: group 1, experimental periodontitis + placebo (PL) (n = 10); group 2, experimental periodontitis + resveratrol (RSV) (n = 10); group 3, experimental periodontitis + curcumin (C) (n = 10); and group 4, experimental periodontitis + resveratrol + curcumin (COMBI) (n = 10). Periodontitis was induced in rats by tying a silk suture, as a ligature, around one of the first molars. Daily administration of the placebo solution, 10 mg/kg of resveratrol, 100 mg/kg of curcumin or 10 mg/kg of resveratrol plus 100 mg/kg of curcumin was carried out from day 0 to day 30. At the end of the relevant experimental periods, rats were killed and the specimens obtained were processed for morphometric analysis of bone loss. Gingival tissues surrounding the first molar were collected for quantification of interleukin (IL)-1β, IL-4, interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) using a Luminex/MAGPIX assay. Intergroup comparisons of the morphometric outcomes revealed higher bone-loss values in the PL group (p < 0.05) when compared with RSV, C and COMBI groups. There was no difference in bone-loss values among RSV, C and COMBI groups (p > 0.05). The immunoenzymatic assay of the gingival tissue showed a lower concentration of IL-1β in the COMBI group in comparison with the PL group (p < 0.05). Higher values of IL-4 were demonstrated in groups RSV, C and COMBI in comparison with the PL group (p < 0.05). Only RSV caused a reduction in the levels of IFN

  2. Failure to obtain value enhancement by within-trial contrast in simultaneous and successive discriminations.

    PubMed

    Arantes, Joana; Grace, Randolph C

    2008-02-01

    The present research tested the generality of the "work ethic" effect described by Clement, Feltus, Kaiser, and Zentall (2000). In Experiment 1, we trained 10 pigeons on a pair of either simultaneous or successive discriminations. One discrimination followed a high-effort requirement (20 pecks to the center key) and the other followed a low-effort requirement (1 peck). Contrary to Clement et al.'s results, we found that preferences between the S+ and S- stimuli in transfer tests depended on the event that initiated the trial: Pigeons preferred the stimulus from the baseline discrimination whose initiating event was most dissimilar from that preceding the test trial. Preferences were similar but less extreme in the successive condition. In Experiment 2, we investigated whether test preferences depended on the amount of training. A total of 12 pigeons were trained on a pair of simultaneous discriminations, except that test sessions were scheduled after every three baseline sessions. Preferences increased across test sessions but were similar to those in Experiment 1. Together with Vasconcelos, Urcuioli, and Lionello-DeNolf (2007a), our study represents a second failure to replicate Clement et al.'s work ethic effect. The finding that preference depends on the event that initiates the test trial suggests that choice probes may not provide unambiguous assessments of stimulus value.

  3. Highly Efficient Design-of-Experiments Methods for Combining CFD Analysis and Experimental Data

    NASA Technical Reports Server (NTRS)

    Anderson, Bernhard H.; Haller, Harold S.

    2009-01-01

    It is the purpose of this study to examine the impact of "highly efficient" Design-of-Experiments (DOE) methods for combining sets of CFD generated analysis data with smaller sets of Experimental test data in order to accurately predict performance results where experimental test data were not obtained. The study examines the impact of micro-ramp flow control on the shock wave boundary layer (SWBL) interaction where a complete paired set of data exist from both CFD analysis and Experimental measurements By combining the complete set of CFD analysis data composed of fifteen (15) cases with a smaller subset of experimental test data containing four/five (4/5) cases, compound data sets (CFD/EXP) were generated which allows the prediction of the complete set of Experimental results No statistical difference were found to exist between the combined (CFD/EXP) generated data sets and the complete Experimental data set composed of fifteen (15) cases. The same optimal micro-ramp configuration was obtained using the (CFD/EXP) generated data as obtained with the complete set of Experimental data, and the DOE response surfaces generated by the two data sets were also not statistically different.

  4. Embedding spiritual value through science learning

    NASA Astrophysics Data System (ADS)

    Johan, H.; Suhandi, A.; Wulan, A. R.; Widiasih; Ruyani, A.; Karyadi, B.; Sipriyadi

    2018-05-01

    The purpose of this study was to embed spiritual value through science learning program especially earth planet. Various phenomena in earth planet describe a divinity of super power. This study used quasi experimental method with one group pre-test-post-test design. Convenience sampling was conducted in this study. 23 pre-service physics teacher was involved. Pre-test and post-test used a questionnaire had been conducted to collected data of spiritual attitude. Open ended question had been utilized at post-test to collected data. A fourth indicators of spiritual value related to divinity of God was used to embed spiritual value. The results show a shifted of students’ awareness to divinity of God. Before implementing the earth planet learning, 85.8% of total students strongly agree that learning activity embed spiritual value while after learning process, it increased be 93.4%. After learning earth planet, it known that students’ spiritual value was influenced by character of earth planet concept which unobservable and media visual which display each incredible phenomena process in our earth planet. It can be concluded that spiritual value can be embedded through unobservable phenomena of during learning earth planet process.

  5. An Experimental Investigation of Sewage Sludge Gasification in a Fluidized Bed Reactor

    PubMed Central

    Calvo, L. F.; García, A. I.; Otero, M.

    2013-01-01

    The gasification of sewage sludge was carried out in a simple atmospheric fluidized bed gasifier. Flow and fuel feed rate were adjusted for experimentally obtaining an air mass : fuel mass ratio (A/F) of 0.2 < A/F < 0.4. Fuel characterization, mass and power balances, produced gas composition, gas phase alkali and ammonia, tar concentration, agglomeration tendencies, and gas efficiencies were assessed. Although accumulation of material inside the reactor was a main problem, this was avoided by removing and adding bed media along gasification. This allowed improving the process heat transfer and, therefore, gasification efficiency. The heating value of the produced gas was 8.4 MJ/Nm, attaining a hot gas efficiency of 70% and a cold gas efficiency of 57%. PMID:24453863

  6. Cross-checking of Large Evaluated and Experimental Nuclear Reaction Databases

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zeydina, O.; Koning, A.J.; Soppera, N.

    2014-06-15

    Automated methods are presented for the verification of large experimental and evaluated nuclear reaction databases (e.g. EXFOR, JEFF, TENDL). These methods allow an assessment of the overall consistency of the data and detect aberrant values in both evaluated and experimental databases.

  7. Effect-based trigger values for in vitro bioassays: Reading across from existing water quality guideline values.

    PubMed

    Escher, Beate I; Neale, Peta A; Leusch, Frederic D L

    2015-09-15

    . The approach is readily adaptable to any water type and guideline or regulatory framework and can be expanded from the protection goal of human health to environmental protection targets. While this work constitutes a proof of principle, the applicability remains limited at present due to insufficient experimental bioassay data on individual regulated chemicals and the derived effect-based trigger values are of course only provisional. Once the experimental database is expanded and made more robust, the proposed effect-based trigger values may provide guidance in a regulatory context. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Experimental Study on Permeability of Concrete

    NASA Astrophysics Data System (ADS)

    Yang, Honglu; Liu, Rentai; Zheng, Zhuo; Liu, Haojie; Gao, Yan; Liu, Yankai

    2018-01-01

    To study the influencing factors on permeability of pervious concrete, by adding inorganic organic composite materials obtained experimental results show that different aggregate size, aggregate cement ratio of different, different water cement ratio on the permeability performance. The permeability of the concrete was tested by using the self - made permeable device. The experimental results showed that the permeation coefficient of the experiment was obtained and the factors influencing the permeability of the concrete were compared and analyzed. At the same time, the porosity of pervious concrete was measured, the influence of various variables on porosity was studied, and the influence of various factors on the permeability of voids was found. Finally, through comprehensive analysis of a variety of factors, the optimal water cement ratio is 0.28. At this time, the pervious performance of concrete is optimal.

  9. Modeling of Receptor Tyrosine Kinase Signaling: Computational and Experimental Protocols.

    PubMed

    Fey, Dirk; Aksamitiene, Edita; Kiyatkin, Anatoly; Kholodenko, Boris N

    2017-01-01

    The advent of systems biology has convincingly demonstrated that the integration of experiments and dynamic modelling is a powerful approach to understand the cellular network biology. Here we present experimental and computational protocols that are necessary for applying this integrative approach to the quantitative studies of receptor tyrosine kinase (RTK) signaling networks. Signaling by RTKs controls multiple cellular processes, including the regulation of cell survival, motility, proliferation, differentiation, glucose metabolism, and apoptosis. We describe methods of model building and training on experimentally obtained quantitative datasets, as well as experimental methods of obtaining quantitative dose-response and temporal dependencies of protein phosphorylation and activities. The presented methods make possible (1) both the fine-grained modeling of complex signaling dynamics and identification of salient, course-grained network structures (such as feedback loops) that bring about intricate dynamics, and (2) experimental validation of dynamic models.

  10. Spectroscopic investigation on structure (monomer and dimer), molecular characteristics and comparative study on vibrational analysis of picolinic and isonicotinic acids using experimental and theoretical (DFT & IVP) methods

    NASA Astrophysics Data System (ADS)

    Ramesh, Gaddam; Reddy, Byru Venkatram

    2018-05-01

    In this investigation, the monomeric structure is determined for picolinic and isonicotinic acids based on geometry optimization for one of the four possible conformers and intramolecular hydrogen bond of Osbnd H⋯O using density functional theory (DFT) employing B3LYP functional supplemented with 6-311++G(d,p) basis set. Using this optimized monomeric form, the dimer structure is determined based on minimum energy and length of hydrogen bonds obtained for two possible dimeric forms yielded due to head-to-tail intermolecular Osbnd H⋯N hydrogen bond (dimer 1) linkage and tail-to -tail intermolecular Osbnd H⋯O hydrogen bond (dimer 2) linkage between pyridine ring and carboxyl group. The structure parameters obtained for monomer and dimer forms are in good agreement with the experimental literature values. The vibrational assignments have been made unambiguously for all the vibrations from FTIR and FT-Raman spectra based on the potential energy distribution (PED) and eigen vectors obtained in DFT and inverse vibrational problem (IVP) computations. The rms error between the observed and scaled frequencies is 7.7 and 9.4 cm-1 for PIA and INA, respectively. A 74-element modified valence force field is derived by Wilson's GF matrix method using 58 experimental frequencies of the two molecules in overlay least-squares technique. The average error between observed and computed frequencies by this method is calculated to be 10.39 cm-1. The results of both DFT and IVP computations yielded good agreement between observed and calculated frequencies. The NLO behaviour using hyperpolarizability values; and HOMO and LUMO energies; of the two molecules are investigated by DFT. Charge density distribution and site of chemical reactivity of the molecules are studied by molecular electrostatic surface potential (MESP). Stability of the molecules arising from hyper conjugative interactions and charge delocalization has been analyzed using natural bond orbital (NBO

  11. A Validity and Reliability Study on the Development of the Values Scale in Turkey

    ERIC Educational Resources Information Center

    Dilmac, Bulent; Aricak, Osman Tolga; Cesur, Sevim

    2014-01-01

    The purpose of the present study is to examine the initial psychometric properties of the Values Scale for adults. While developing the first stage of the Values Scale, open-ended data on the values held by 216 university students were obtained. During the second stage, the validity and reliability studies of the 60-item Values Scale obtained by…

  12. Arousing "gentle passions" in young adolescents: Sustained experimental effects of value affirmations on prosocial feelings and behaviors.

    PubMed

    Thomaes, Sander; Bushman, Brad J; de Castro, Bram Orobio; Reijntjes, Albert

    2012-01-01

    When people reflect on their important values, they may become more attuned to the needs of others. Two longitudinal field experiments examined whether a subtle value-affirmation manipulation can initiate relatively enduring increases in young adolescents' prosocial feelings (Study 1; Mage = 12.9) and prosocial behaviors (Study 2; Mage = 12.9). Participants completed a brief writing exercise that affirmed the values they deemed either most important (value-affirmation group) or unimportant (control group). As predicted, the value affirmation, coupled with a booster affirmation 6 weeks later, caused increases in prosocial feelings and behaviors over the 3-month study period. Antisocial students who were value-affirmed showed especially strong increases in prosocial behavior. These results suggest that "gentle passions" can be aroused in youth by cost- and time-efficient means. The practical utility of value affirmations will need to be evaluated in future work.

  13. Gender, values, and occupational interests among children, adolescents, and adults.

    PubMed

    Weisgram, Erica S; Bigler, Rebecca S; Liben, Lynn S

    2010-01-01

    Work fulfills personal values, perhaps differently for males and females. Explored here was the role values play in shaping occupational interests. Study 1 examined children's, adolescents', and adults' (N = 313) occupational values (regarding money, power, family, altruism), occupational interests, and perceptions of values afforded by traditionally masculine and feminine occupations. Results revealed sex differences in occupational values and interests. Furthermore, participants' values predicted their own interests in culturally masculine and feminine occupations. Study 2 used novel jobs and experimentally manipulated prototypical sex of worker and value affordances to disentangle their effects on occupational interests. At all ages, participants' (N = 240) occupational interests were affected by the depicted sex of the workers and by the stated value affordances of the jobs.

  14. Effects of Erdosteine on Experimental Acute Pancreatitis Model.

    PubMed

    Karapolat, Banu; Karapolat, Sami; Gurleyik, Emin; Yasar, Mehmet

    2017-10-01

    To create acute pancreatitis condition experimentally in rats using cerulein, and to reveal histopathological effects in pancreatic tissue with erdosteine. An experimental study. Department of General Surgery, Duzce University, Turkey, from June to October 2014. Thirty male Wistar albino rats were divided into three groups. No procedures were applied to Group 1. The rats in Group 2 and Group 3 were injected cerulein, to establish an experimental pancreatitis model and the blood amylase and lipase values were examined. The rats in Group 3 were given 10 mg/kg erdosteine. This treatment was continued for another 2 days and the rats were sacrificed. The pancreatic tissues were examined histopathologically for edema, inflammation, acinar necrosis, fat necrosis, and vacuolization. The lipase and amylase values and the histopathological examination of pancreatic tissues evidenced that the experimental acute pancreatitis model was established and edema, inflammation, acinar necrosis, fat necrosis, and vacuolization were observed in the pancreatic tissues. The statistical results suggest that erdosteine can decrease the edema, inflammation, acinar necrosis, fat necrosis and vacuolization scores in the tissues. The severity of acute pancreatitis, induced by cerulein in rats, is reduced with the use of erdosteine.

  15. Nonlinear experimental dye-doped nematic liquid crystal optical transmission spectra estimated by neural network empirical physical formulas

    NASA Astrophysics Data System (ADS)

    Yildiz, Nihat; San, Sait Eren; Köysal, Oğuz

    2010-09-01

    In this paper, two complementary objectives related to optical transmission spectra of nematic liquid crystals (NLCs) were achieved. First, at room temperature, for both pure and dye (DR9) doped E7 NLCs, the 10-250 W halogen lamp transmission spectra (wavelength 400-1200 nm) were measured at various bias voltages. Second, because the measured spectra were inherently highly nonlinear, it was difficult to construct explicit empirical physical formulas (EPFs) to employ as transmittance functions. To avoid this difficulty, layered feedforward neural networks (LFNNs) were used to construct explicit EPFs for these theoretically unknown nonlinear NLC transmittance functions. As we theoretically showed in a previous work, a LFNN, as an excellent nonlinear function approximator, is highly relevant to EPF construction. The LFNN-EPFs efficiently and consistently estimated both the measured and yet-to-be-measured nonlinear transmittance response values. The experimentally obtained doping ratio dependencies and applied bias voltage responses of transmittance were also confirmed by LFFN-EPFs. This clearly indicates that physical laws embedded in the physical data can be faithfully extracted by the suitable LFNNs. The extraordinary success achieved with LFNN here suggests two potential applications. First, although not attempted here, these LFNN-EPFs, by such mathematical operations as derivation, integration, minimization etc., can be used to obtain further transmittance related functions of NLCs. Second, for a given NLC response function, whose theoretical nonlinear functional form is yet unknown, a suitable experimental data based LFNN-EPF can be constructed to predict the yet-to-be-measured values.

  16. Experimental conformational energy maps of proteins and peptides.

    PubMed

    Balaji, Govardhan A; Nagendra, H G; Balaji, Vitukudi N; Rao, Shashidhar N

    2017-06-01

    We have presented an extensive analysis of the peptide backbone dihedral angles in the PDB structures and computed experimental Ramachandran plots for their distributions seen under a various constraints on X-ray resolution, representativeness at different sequence identity percentages, and hydrogen bonding distances. These experimental distributions have been converted into isoenergy contour plots using the approach employed previously by F. M. Pohl. This has led to the identification of energetically favored minima in the Ramachandran (ϕ, ψ) plots in which global minima are predominantly observed either in the right-handed α-helical or the polyproline II regions. Further, we have identified low energy pathways for transitions between various minima in the (ϕ,ψ) plots. We have compared and presented the experimental plots with published theoretical plots obtained from both molecular mechanics and quantum mechanical approaches. In addition, we have developed and employed a root mean square deviation (RMSD) metric for isoenergy contours in various ranges, as a measure (in kcal.mol -1 ) to compare any two plots and determine the extent of correlation and similarity between their isoenergy contours. In general, we observe a greater degree of compatibility with experimental plots for energy maps obtained from molecular mechanics methods compared to most quantum mechanical methods. The experimental energy plots we have investigated could be helpful in refining protein structures obtained from X-ray, NMR, and electron microscopy and in refining force field parameters to enable simulations of peptide and protein structures that have higher degree of consistency with experiments. Proteins 2017; 85:979-1001. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  17. Whey-derived valuable products obtained by microbial fermentation.

    PubMed

    Pescuma, Micaela; de Valdez, Graciela Font; Mozzi, Fernanda

    2015-08-01

    Whey, the main by-product of the cheese industry, is considered as an important pollutant due to its high chemical and biological oxygen demand. Whey, often considered as waste, has high nutritional value and can be used to obtain value-added products, although some of them need expensive enzymatic synthesis. An economical alternative to transform whey into valuable products is through bacterial or yeast fermentations and by accumulation during algae growth. Fermentative processes can be applied either to produce individual compounds or to formulate new foods and beverages. In the first case, a considerable amount of research has been directed to obtain biofuels able to replace those derived from petrol. In addition, the possibility of replacing petrol-derived plastics by biodegradable polymers synthesized during bacterial fermentation of whey has been sought. Further, the ability of different organisms to produce metabolites commonly used in the food and pharmaceutical industries (i.e., lactic acid, lactobionic acid, polysaccharides, etc.) using whey as growth substrate has been studied. On the other hand, new low-cost functional whey-based foods and beverages leveraging the high nutritional quality of whey have been formulated, highlighting the health-promoting effects of fermented whey-derived products. This review aims to gather the multiple uses of whey as sustainable raw material for the production of individual compounds, foods, and beverages by microbial fermentation. This is the first work to give an overview on the microbial transformation of whey as raw material into a large repertoire of industrially relevant foods and products.

  18. Experimental and Theoretical Study of Heat Conduction for Air up to 5000 K

    NASA Technical Reports Server (NTRS)

    Peng, Tzy-Cheng; Ahtye, Warren F.

    1961-01-01

    The theoretical value of the integral of thermal conductivity is compared with the experimental values from shock-tube measurements. The particular case considered is the one-dimensional nonsteady flow of heat through air at constant pressure. This approach has been previously described in NASA TR R-27. experiment was uncertain because of the large scatter in the experimental data. In this paper, an attempt is made to improve the correlation by use of a more refined calculation of the integral of thermal conductivity, and by use of improved experimental techniques and instrumentation. As a result of these changes, a much closer correlation is shown between the experimental and theoretical heat-flux potentials. This indicates that the predicted values of the coefficient of thermal conductivity for high-temperature air may be suitably accurate for many engineering needs, up to the limits of the test (4600 K).

  19. Applying a Hypoxia-Incorporating TCP Model to Experimental Data on Rat Sarcoma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ruggieri, Ruggero, E-mail: ruggieri.ruggero@gmail.com; Stavreva, Nadejda; Naccarato, Stefania

    2012-08-01

    Purpose: To verify whether a tumor control probability (TCP) model which mechanistically incorporates acute and chronic hypoxia is able to describe animal in vivo dose-response data, exhibiting tumor reoxygenation. Methods and Materials: The investigated TCP model accounts for tumor repopulation, reoxygenation of chronic hypoxia, and fluctuating oxygenation of acute hypoxia. Using the maximum likelihood method, the model is fitted to Fischer-Moulder data on Wag/Rij rats, inoculated with rat rhabdomyosarcoma BA1112, and irradiated in vivo using different fractionation schemes. This data set is chosen because two of the experimental dose-response curves exhibit an inverse dose behavior, which is interpreted as duemore » to reoxygenation. The tested TCP model is complex, and therefore, in vivo cell survival data on the same BA1112 cell line from Reinhold were added to Fischer-Moulder data and fitted simultaneously with a corresponding cell survival function. Results: The obtained fit to the combined Fischer-Moulder-Reinhold data was statistically acceptable. The best-fit values of the model parameters for which information exists were in the range of published values. The cell survival curves of well-oxygenated and hypoxic cells, computed using the best-fit values of the radiosensitivities and the initial number of clonogens, were in good agreement with the corresponding in vitro and in situ experiments of Reinhold. The best-fit values of most of the hypoxia-related parameters were used to recompute the TCP for non-small cell lung cancer patients as a function of the number of fractions, TCP(n). Conclusions: The investigated TCP model adequately describes animal in vivo data exhibiting tumor reoxygenation. The TCP(n) curve computed for non-small cell lung cancer patients with the best-fit values of most of the hypoxia-related parameters confirms previously obtained abrupt reduction in TCP for n < 10, thus warning against the adoption of severely hypofractionated

  20. Theoretical and experimental analysis of the contact between a solid-rubber tire and a chassis dynamometer

    NASA Astrophysics Data System (ADS)

    Belkin, A. E.; Semenov, V. K.

    2016-05-01

    We consider the problem of modeling the test where a solid-rubber tire runs on a chassis dynamometer for determining the tire rolling resistance characteristics.We state the problem of free steady-state rolling of the tire along the test drum with the energy scattering in the rubber in the course of cyclic deformation taken into account. The viscoelastic behavior of the rubber is described by the Bergströ m-Boyce model whose numerical parameters are experimentally determined from the results of compression tests with specimens. The finite element method is used to obtain the solution of the three-dimensional viscoelasticity problem. To estimate the adequacy of the constructed model, we compare the numerical results with the results obtained in the solid-rubber tire tests on the Hasbach stand from the values of the rolling resistance forces for various loads on the tire.

  1. Fungicidal values of bio-oils and their lignin-rich fractions obtained from wood/bark fast pyrolysis.

    PubMed

    Mohan, Dinesh; Shi, Jenny; Nicholas, Darrel D; Pittman, Charles U; Steele, Philip H; Cooper, Jerome E

    2008-03-01

    Pine wood, pine bark, oak wood and oak bark were pyrolyzed in an auger reactor. A total of 16 bio-oils or pyrolytic oils were generated at different temperatures and residence times. Two additional pine bio-oils were produced at the National Renewable Energy Laboratory in a fluidized-bed reactor at different temperatures. All these bio-oils were fractionated to obtain lignin-rich fractions which consist mainly of phenols and neutrals. The pyrolytic lignin-rich fractions were obtained by liquid-liquid extraction. Whole bio-oils and their lignin-rich fractions were studied as potential environmentally benign wood preservatives to replace metal-based CCA and copper systems that have raised environmental concerns. Each bio-oil and several lignin-rich fractions were tested for antifungal properties. Soil block tests were conducted using one brown-rot fungus (Gloeophyllum trabeum) and one white-rot fungus (Trametes versicolor). The lignin-rich fractions showed greater fungal inhibition than whole bio-oils for a impregnation solution 10% concentration level. Water repellence tests were also performed to study wood wafer swelling behavior before and after bio-oil and lignin-rich fraction treatments. In this case, bio-oil fractions did not exhibit higher water repellency than whole bio-oils. Comparison of raw bio-oils in soil block tests, with unleached wafers, at 10% and 25% bio-oil impregnation solution concentration levels showed excellent wood preservation properties at the 25% level. The good performance of raw bio-oils at higher loading levels suggests that fractionation to generate lignin-rich fractions is unnecessary. At this more effective 25% loading level in general, the raw bio-oils performed similarly. Prevention of leaching is critically important for both raw bio-oils and their fractions to provide decay resistance. Initial tests of a polymerization chemical to prevent leaching showed some success.

  2. Experimental design and response surface modelling for optimization of vat dye from water by nano zero valent iron (NZVI).

    PubMed

    Arabi, Simin; Sohrabi, Mahmoud Reza

    2013-01-01

    In this study, NZVI particles was prepared and studied for the removal of vat green 1 dye from aqueous solution. A four-factor central composite design (CCD) combined with response surface modeling (RSM) to evaluate the combined effects of variables as well as optimization was employed for maximizing the dye removal by prepared NZVI based on 30 different experimental data obtained in a batch study. Four independent variables, viz. NZVI dose (0.1-0.9 g/L), pH (1.5-9.5), contact time (20-100 s), and initial dye concentration (10-50 mg/L) were transform to coded values and quadratic model was built to predict the responses. The significant of independent variables and their interactions were tested by the analysis of variance (ANOVA). Adequacy of the model was tested by the correlation between experimental and predicted values of the response and enumeration of prediction errors. The ANOVA results indicated that the proposed model can be used to navigate the design space. Optimization of the variables for maximum adsorption of dye by NZVI particles was performed using quadratic model. The predicted maximum adsorption efficiency (96.97%) under the optimum conditions of the process variables (NZVI dose 0.5 g/L, pH 4, contact time 60 s, and initial dye concentration 30 mg/L) was very close to the experimental value (96.16%) determined in batch experiment. In the optimization, R2 and R2adj correlation coefficients for the model were evaluated as 0.95 and 0.90, respectively.

  3. All inequality is not equal: children correct inequalities using resource value.

    PubMed

    Shaw, Alex; Olson, Kristina R

    2013-01-01

    Fairness concerns guide children's judgments about how to share resources with others. However, it is unclear from past research if children take extant inequalities or the value of resources involved in an inequality into account when sharing with others; these questions are the focus of the current studies. In all experiments, children saw an inequality between two recipients-one had two more resources than another. What varied between conditions was the value of the resources that the child could subsequently distribute. When the resources were equal in value to those involved in the original inequality, children corrected the previous inequality by giving two resources to the child with fewer resources (Experiment 1). However, as the value of the resources increased relative to those initially shared by the experimenter, children were more likely to distribute the two high value resources equally between the two recipients, presumably to minimize the overall inequality in value (Experiments 1 and 2). We found that children specifically use value, not just size, when trying to equalize outcomes (Experiment 3) and further found that children focus on the relative rather than absolute value of the resources they share-when the experimenter had unequally distributed the same high value resource that the child would later share, children corrected the previous inequality by giving two high value resources to the person who had received fewer high value resources. These results illustrate that children attempt to correct past inequalities and try to maintain equality not just in the count of resources but also by using the value of resources.

  4. All inequality is not equal: children correct inequalities using resource value

    PubMed Central

    Shaw, Alex; Olson, Kristina R.

    2013-01-01

    Fairness concerns guide children's judgments about how to share resources with others. However, it is unclear from past research if children take extant inequalities or the value of resources involved in an inequality into account when sharing with others; these questions are the focus of the current studies. In all experiments, children saw an inequality between two recipients—one had two more resources than another. What varied between conditions was the value of the resources that the child could subsequently distribute. When the resources were equal in value to those involved in the original inequality, children corrected the previous inequality by giving two resources to the child with fewer resources (Experiment 1). However, as the value of the resources increased relative to those initially shared by the experimenter, children were more likely to distribute the two high value resources equally between the two recipients, presumably to minimize the overall inequality in value (Experiments 1 and 2). We found that children specifically use value, not just size, when trying to equalize outcomes (Experiment 3) and further found that children focus on the relative rather than absolute value of the resources they share—when the experimenter had unequally distributed the same high value resource that the child would later share, children corrected the previous inequality by giving two high value resources to the person who had received fewer high value resources. These results illustrate that children attempt to correct past inequalities and try to maintain equality not just in the count of resources but also by using the value of resources. PMID:23882227

  5. Molecular simulations and experimental studies of solubility and diffusivity for pure and mixed gases of H2, CO2, and Ar absorbed in the ionic liquid 1-n-hexyl-3-methylimidazolium bis(trifluoromethylsulfonyl)amide ([hmim][Tf2N]).

    PubMed

    Shi, Wei; Sorescu, Dan C; Luebke, David R; Keller, Murphy J; Wickramanayake, Shan

    2010-05-20

    Classical molecular dynamics and Monte Carlo simulations are used to calculate the self-diffusivity and solubility of pure and mixed CO(2), H(2), and Ar gases absorbed in the ionic liquid 1-n-hexyl-3-methylimidazolium bis(trifluoromethylsulfonyl)amide ([hmim][Tf(2)N]). Overall, the computed absorption isotherms, Henry's law constants, and partial molar enthalpies for pure H(2) agree well with the experimental data obtained by Maurer et al. [J. Chem. Eng. Data 2006, 51, 1364] and the experimental values determined in this work. However, the agreement is poor between the simulations and the experimental data by Noble et al. [Ind. Eng. Chem. Res. 2008, 47, 3453] and Costa Gomes [J. Chem. Eng. Data 2007, 52, 472] at high temperatures. The computed H(2) permeability values are in good agreement with the experimental data at 313 K obtained by Luebke et al. [J. Membr. Sci. 2007, 298, 41; ibid, 2008, 322, 28], but about three times larger than the experimental value at 573 K from the same group. Our computed H(2) solubilities using different H(2) potential models have similar values and solute polarizations were found to have a negligible effect on the predicted gas solubilities for both the H(2) and Ar. The interaction between H(2) and the ionic liquid is weak, about three times smaller than between the ionic liquid and Ar and six times smaller than that of CO(2) with the ionic liquid, results that are consistent with a decreasing solubility from CO(2) to Ar and to H(2). The molar volume of the ionic liquid was found to be the determining factor for the H(2) solubility. For mixed H(2) and Ar gases, the solubilities for both solutes decrease compared to the respective pure gas solubilities. For mixed gases of CO(2) and H(2), the solubility selectivity of CO(2) over H(2) decreases from about 30 at 313 K to about 3 at 573 K. For the permeability, the simulated values for CO(2) in [hmim][Tf(2)N] are about 20-60% different than the experimental data by Luebke et al. [J. Membr

  6. Quantum interval-valued probability: Contextuality and the Born rule

    NASA Astrophysics Data System (ADS)

    Tai, Yu-Tsung; Hanson, Andrew J.; Ortiz, Gerardo; Sabry, Amr

    2018-05-01

    We present a mathematical framework based on quantum interval-valued probability measures to study the effect of experimental imperfections and finite precision measurements on defining aspects of quantum mechanics such as contextuality and the Born rule. While foundational results such as the Kochen-Specker and Gleason theorems are valid in the context of infinite precision, they fail to hold in general in a world with limited resources. Here we employ an interval-valued framework to establish bounds on the validity of those theorems in realistic experimental environments. In this way, not only can we quantify the idea of finite-precision measurement within our theory, but we can also suggest a possible resolution of the Meyer-Mermin debate on the impact of finite-precision measurement on the Kochen-Specker theorem.

  7. Influence of experimental parameters on iron oxide nanoparticle properties synthesized by thermal decomposition: size and nuclear magnetic resonance studies

    NASA Astrophysics Data System (ADS)

    Belaïd, Sarah; Stanicki, Dimitri; Vander Elst, Luce; Muller, Robert N.; Laurent, Sophie

    2018-04-01

    A study of the experimental conditions to synthesize monodisperse iron oxide nanocrystals prepared from the thermal decomposition of iron(III) acetylacetonate was carried out in the presence of surfactants and a reducing agent. The influence of temperature, synthesis time and surfactant amounts on nanoparticle properties is reported. This investigation combines relaxometric characterization and size properties. The relaxometric behavior of the nanomaterials depends on the selected experimental parameters. The synthesis of iron oxide nanoparticles with a high relaxivity and a high saturation magnetization can be obtained with a short reaction time at high temperature. Moreover, the influence of surfactant concentrations determines the optimal value in order to produce iron oxide nanoparticles with a narrow size distribution. The optimized synthesis is rapid, robust and reproductive, and produces nearly monodisperse magnetic nanocrystals.

  8. Infrared dim-small target tracking via singular value decomposition and improved Kernelized correlation filter

    NASA Astrophysics Data System (ADS)

    Qian, Kun; Zhou, Huixin; Rong, Shenghui; Wang, Bingjian; Cheng, Kuanhong

    2017-05-01

    Infrared small target tracking plays an important role in applications including military reconnaissance, early warning and terminal guidance. In this paper, an effective algorithm based on the Singular Value Decomposition (SVD) and the improved Kernelized Correlation Filter (KCF) is presented for infrared small target tracking. Firstly, the super performance of the SVD-based algorithm is that it takes advantage of the target's global information and obtains a background estimation of an infrared image. A dim target is enhanced by subtracting the corresponding estimated background with update from the original image. Secondly, the KCF algorithm is combined with Gaussian Curvature Filter (GCF) to eliminate the excursion problem. The GCF technology is adopted to preserve the edge and eliminate the noise of the base sample in the KCF algorithm, helping to calculate the classifier parameter for a small target. At last, the target position is estimated with a response map, which is obtained via the kernelized classifier. Experimental results demonstrate that the presented algorithm performs favorably in terms of efficiency and accuracy, compared with several state-of-the-art algorithms.

  9. Assessment and improvement of statistical tools for comparative proteomics analysis of sparse data sets with few experimental replicates.

    PubMed

    Schwämmle, Veit; León, Ileana Rodríguez; Jensen, Ole Nørregaard

    2013-09-06

    Large-scale quantitative analyses of biological systems are often performed with few replicate experiments, leading to multiple nonidentical data sets due to missing values. For example, mass spectrometry driven proteomics experiments are frequently performed with few biological or technical replicates due to sample-scarcity or due to duty-cycle or sensitivity constraints, or limited capacity of the available instrumentation, leading to incomplete results where detection of significant feature changes becomes a challenge. This problem is further exacerbated for the detection of significant changes on the peptide level, for example, in phospho-proteomics experiments. In order to assess the extent of this problem and the implications for large-scale proteome analysis, we investigated and optimized the performance of three statistical approaches by using simulated and experimental data sets with varying numbers of missing values. We applied three tools, including standard t test, moderated t test, also known as limma, and rank products for the detection of significantly changing features in simulated and experimental proteomics data sets with missing values. The rank product method was improved to work with data sets containing missing values. Extensive analysis of simulated and experimental data sets revealed that the performance of the statistical analysis tools depended on simple properties of the data sets. High-confidence results were obtained by using the limma and rank products methods for analyses of triplicate data sets that exhibited more than 1000 features and more than 50% missing values. The maximum number of differentially represented features was identified by using limma and rank products methods in a complementary manner. We therefore recommend combined usage of these methods as a novel and optimal way to detect significantly changing features in these data sets. This approach is suitable for large quantitative data sets from stable isotope labeling

  10. Development of the virtual experimental bench on the basis of modernized research centrifugal compressor stage test unit with the 3D impeller.

    NASA Astrophysics Data System (ADS)

    Aksenov, A. A.; Danilishin, A. M.; Dubenko, A. M.; Kozhukov, Y. V.

    2017-08-01

    Design modernization of the centrifugal compressor stage test bench with three dimensional impeller blades was carried out for the possibility of holding a series of experimental studies of different 3D impeller models. The studies relates to the problem of joint work of the impeller and the stationary channels of the housing when carrying out works on modernization with the aim of improving the parameters of the volumetric capacity or pressure in the presence of design constraints. The object of study is the experimental single end centrifugal compressor stage with the 3D impeller. Compressor stage consists of the 3D impeller, vaneless diffuser (VLD), outlet collector - folded side scroll and downstream pipe. The drive is a DC motor 75 kW. The increase gear (multiplier) was set between the compressor and DC motor, gear ratio is i = 9.8. To obtain the characteristics of the compressor and the flow area the following values were measured: total pressure, static pressure, direction (angles) of the stream in different cross sections. Additional pneumometric probes on the front wall of the VLD of the test bench have been installed. Total pressure probes and foster holes for the measurement of total and static pressure by the new drainage scheme. This allowed carrying out full experimental studies for two elements of centrifugal compressor stage. After the experimental tests the comprehensive information about the performance of model stage were obtained. Was measured geometric parameters and the constructed virtual model of the experimental bench flow part with the help of Creo Parametric 3.0 and ANSYS v. 16.2. Conducted CFD calculations and verification with experimental data. Identifies the steps for further experimental and virtual works.

  11. Experimental entanglement of a six-photon symmetric Dicke state.

    PubMed

    Wieczorek, Witlef; Krischek, Roland; Kiesel, Nikolai; Michelberger, Patrick; Tóth, Géza; Weinfurter, Harald

    2009-07-10

    We report on the experimental observation and characterization of a six-photon entangled Dicke state. We obtain a fidelity as high as 0.654+/-0.024 and prove genuine six-photon entanglement by, amongst others, a two-setting witness yielding -0.422+/-0.148. This state has remarkable properties; e.g., it allows obtaining inequivalent entangled states of a lower qubit number via projective measurements, and it possesses a high entanglement persistency against qubit loss. We characterize the properties of the six-photon Dicke state experimentally by detecting and analyzing the entanglement of a variety of multipartite entangled states.

  12. a Theoretical and Experimental Investigation of 1/F Noise in the Alpha Decay Rates of AMERICIUM-241.

    NASA Astrophysics Data System (ADS)

    Pepper, Gary T.

    New experimental methods and data analysis techniques were used to investigate the hypothesis of the existence of 1/f noise in a alpha particle emission rates for ^{241}Am. Experimental estimates of the flicker floor were found to be almost two orders of magnitude less than Handel's theoretical prediction and previous measurements. The existence of a flicker floor for ^{57}Co decay, a process for which no charged particles are emitted, indicate that instrumental instability is likely responsible for the values of the flicker floor obtained. The experimental results and the theoretical arguments presented indicate that a re-examination of Handel's theory of 1/f noise is appropriate. Methods of numerical simulation of noise processes with a 1/f^{rm n} power spectral density were developed. These were used to investigate various statistical aspects of 1/f ^{rm n} noise. The probability density function for the Allan variance was investigated in order to establish confidence limits for the observations made. The effect of using grouped (correlated) data, for evaluating the Allan variance, was also investigated.

  13. Provisional hourly values of equatorial Dst for 1971

    NASA Technical Reports Server (NTRS)

    Sugiura, M.; Poros, D. J.

    1972-01-01

    Tables and plots of provisional hourly values of the equatorial Dst index for 1971 are given, a table of daily mean Dst values for 1971 is also provided. The base line values for the four observatories, Hermanus, Kakioka, Honolulu, and San Juan, were obtained from extrapolations using the coefficients for the secular variations determined for the previous years. Examining the Dst values for quiet days, the base lines so determined appear to be slightly low, so that the Dst index for quiet periods tends to be high.

  14. Experimental violation of a Bell's inequality with efficient detection.

    PubMed

    Rowe, M A; Kielpinski, D; Meyer, V; Sackett, C A; Itano, W M; Monroe, C; Wineland, D J

    2001-02-15

    Local realism is the idea that objects have definite properties whether or not they are measured, and that measurements of these properties are not affected by events taking place sufficiently far away. Einstein, Podolsky and Rosen used these reasonable assumptions to conclude that quantum mechanics is incomplete. Starting in 1965, Bell and others constructed mathematical inequalities whereby experimental tests could distinguish between quantum mechanics and local realistic theories. Many experiments have since been done that are consistent with quantum mechanics and inconsistent with local realism. But these conclusions remain the subject of considerable interest and debate, and experiments are still being refined to overcome 'loopholes' that might allow a local realistic interpretation. Here we have measured correlations in the classical properties of massive entangled particles (9Be+ ions): these correlations violate a form of Bell's inequality. Our measured value of the appropriate Bell's 'signal' is 2.25 +/- 0.03, whereas a value of 2 is the maximum allowed by local realistic theories of nature. In contrast to previous measurements with massive particles, this violation of Bell's inequality was obtained by use of a complete set of measurements. Moreover, the high detection efficiency of our apparatus eliminates the so-called 'detection' loophole.

  15. An angle-by-angle approach to predicting broadband high-frequency sound fields in rectangular enclosures with experimental comparison.

    PubMed

    Franzoni, Linda P; Elliott, Christopher M

    2003-10-01

    Experiments were performed on an elongated rectangular acoustic enclosure with different levels of absorptive material placed on side walls and an end wall. The acoustic source was a broadband high-frequency sound from a loudspeaker flush-mounted to an end wall of the enclosure. Measurements of sound-pressure levels were averaged in cross sections of the enclosure and then compared to theoretical results. Discrepancies between the experimental results and theoretical predictions that treated all incidence angles as equally probable led to the development of an angle-by-angle approach. The new approach agrees well with the experimentally obtained values. In addition, treating the absorptive material as bulk reacting rather than point reacting was found to significantly change the theoretical value for the absorption coefficient and to improve agreement with experiment. The new theory refines an earlier theory based on power conservation and locally diffuse assumptions. Furthermore, the new theory includes both the angle of incidence effects on the resistive and reactive properties of the absorptive material, and the effects of angle filtering, i.e., that reflecting waves associated with shallow angles become relatively stronger than those associated with steep angles as a function of distance from the source.

  16. Experimental and numerical study of the British Experimental Rotor Programme blade

    NASA Technical Reports Server (NTRS)

    Brocklehurst, Alan; Duque, Earl P. N.

    1990-01-01

    Wind-tunnel tests on the British Experimental Rotor Programme (BERP) tip are described, and the results are compared with computational fluid dynamics (CFD) results. The test model was molded using the Lynx-BERP blade tooling to provide a semispan, cantilever wing comprising the outboard 30 percent of the rotor blade. The tests included both surface-pressure measurements and flow visualization to obtain detailed information of the flow over the BERP tip for a range of angles of attack. It was observed that, outboard of the notch, favorable pressure gradients exist which ensure attached flow, and that the tip vortex also remains stable to large angles of attack. On the rotor, these features yield a very gradual break in control loads when the retreating-blade limit is eventually reached. Computational and experimental results were generally found to be in good agreement.

  17. Patients' Perspective on the Value of Medication Management Appointments.

    PubMed

    Cruz, Mario; Cruz, Robyn Flaum; Pincus, Harold Alan

    2015-05-20

    There is ongoing concern that psychiatric medication management appointments add little value to care. The present study attempted to address this concern by capturing depressed patients' views and opinions about the value of psychiatric medication management appointments. Seventy-eight semi-structured interviews were performed with white and African American depressed patients post medication management appointments. These interviews tapped patients' views and opinions about the value of attending medication management appointments. An iterative thematic analysis was performed. Patients reported greater appointment value when appointments included obtaining medications, discussing the need for medication changes or dose adjustments, and discussing the impact of medications on their illness. Additionally, greater appointment value was perceived by patients when there were non-medical conversations about life issues, immediate outcomes from the appointment such as motivation to continue in care, and specific qualities of providers that were appealing to patients. Patients' perceived value of psychiatric medication management appointments is complex. Though important patient outcomes are obtaining medicine and perceiving improvement in their mental health, there are other valued appointment and provider factors. Some of these other valued factors embedded within medication management appointments could have therapeutic properties. These findings have implications for future clinical research and service delivery.

  18. Watermarking scheme based on singular value decomposition and homomorphic transform

    NASA Astrophysics Data System (ADS)

    Verma, Deval; Aggarwal, A. K.; Agarwal, Himanshu

    2017-10-01

    A semi-blind watermarking scheme based on singular-value-decomposition (SVD) and homomorphic transform is pro-posed. This scheme ensures the digital security of an eight bit gray scale image by inserting an invisible eight bit gray scale wa-termark into it. The key approach of the scheme is to apply the homomorphic transform on the host image to obtain its reflectance component. The watermark is embedded into the singular values that are obtained by applying the singular value decomposition on the reflectance component. Peak-signal-to-noise-ratio (PSNR), normalized-correlation-coefficient (NCC) and mean-structural-similarity-index-measure (MSSIM) are used to evaluate the performance of the scheme. Invisibility of watermark is ensured by visual inspection and high value of PSNR of watermarked images. Presence of watermark is ensured by visual inspection and high values of NCC and MSSIM of extracted watermarks. Robustness of the scheme is verified by high values of NCC and MSSIM for attacked watermarked images.

  19. Correlation between radio-induced lymphocyte apoptosis measurements obtained from two French centres.

    PubMed

    Mirjolet, C; Merlin, J L; Dalban, C; Maingon, P; Azria, D

    2016-07-01

    In the era of modern treatment delivery, increasing the dose delivered to the target to improve local control might be modulated by the patient's intrinsic radio-sensitivity. A predictive assay based on radio-induced lymphocyte apoptosis quantification highlighted the significant correlation between CD4 and CD8 T-lymphocyte apoptosis and grade 2 or 3 radiation-induced late toxicities. By conducting this assay at several technical platforms, the aim of this study was to demonstrate that radio-induced lymphocyte apoptosis values obtained from two different platforms were comparable. For 25 patients included in the PARATOXOR trial running in Dijon the radio-induced lymphocyte apoptosis results obtained from the laboratory of Montpellier (IRCM, Inserm U1194, France), considered as the reference (referred to as Lab 1), were compared with those from the laboratory located at the Institut de cancérologie de Lorraine (ICL, France), referred to as Lab 2. Different statistical methods were used to measure the agreement between the radio-induced lymphocyte apoptosis data from the two laboratories (quantitative data). The Bland-Altman plot was used to identify potential bias. All statistical tests demonstrated good agreement between radio-induced lymphocyte apoptosis values obtained from both sites and no major bias was identified. Since radio-induced lymphocyte apoptosis values, which predict tolerance to radiotherapy, could be assessed by two laboratories and showed a high level of robustness and consistency, we can suggest that this assay be extended to any laboratories that use the same technique. Copyright © 2016 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.

  20. Determination of molar enthalpy of sublimation in case of orotic acid as obtained from experimental and computational data

    NASA Astrophysics Data System (ADS)

    Marochkin, Ilya I.; Altova, Ekaterina P.; Chilingarov, Norbert S.; Vilkova, Anna L.; Shishkov, Igor F.

    2018-03-01

    Saturated vapor pressure, ln(p/Pa) = (-21316 ± 511)/(T/K)+(41.64 ± 0.11), and enthalpy of sublimation of orotic acid, Δsub Hm0 (Tm) = 177 ± 4 kJ/mol, were determined by means of Knudsen effusion mass spectrometry in the temperature range of 423÷493 K. The computational approaches supported the experimental results reported. The theoretical estimation of the gas-phase enthalpy of formation for orotic acid was done with different working reactions used.

  1. Equation of state of zircon- and scheelite-type dysprosium orthovanadates: a combined experimental and theoretical study.

    PubMed

    Paszkowicz, Wojciech; Ermakova, Olga; López-Solano, Javier; Mujica, Andrés; Muñoz, Alfonso; Minikayev, Roman; Lathe, Christian; Gierlotka, Stanisław; Nikolaenko, Irina; Dabkowska, Hanna

    2014-01-15

    Dysprosium orthovanadate, DyVO4, belongs to a family of zircon-type orthovanadates showing a phase transition to scheelite-type structures at moderate pressures below 10 GPa. In the present study, the equations of state (EOSs) for both these phases were determined for the first time using high-pressure x-ray diffraction experiments and ab initio calculations based on the density functional theory. Structural parameters for scheelite-type DyVO4 were calculated from x-ray powder diffraction data as well. The high-pressure experiments were performed under pseudo-hydrostatic conditions at pressures up to 8.44 GPa and 5.5 GPa for the stable zircon-type and metastable (quenched) scheelite-type samples, respectively. Assuming as a compression model the Birch-Murnaghan EOS, we obtained the EOS parameters for both phases. The experimental bulk moduli (K0) for zircon-type and scheelite-type DyVO4 are 118(4) GPa and 153(6) GPa, respectively. Theoretical equations of state were determined by ab initio calculations using the PBE exchange-correlation energy functional of Perdew, Burke, and Ernzerhof. These calculations provide K0 values of 126.1 GPa and 142.9 GPa for zircon-type and scheelite-type DyVO4, respectively. The reliability of the present experimental and theoretical results is supported by (i) the consistency between the values yielded by the two methods (the discrepancy in K0 is as low as about 7% for each of the studied polymorphs) and (ii) their similarity to results obtained under similar compression conditions (hydrostatic or pseudo-hydrostatic) for other rare-earth orthovanadates, such as YVO4 and TbVO4.

  2. Analysis of Thermal Energy Storage Tank by ANSYS and Comparison with Experimental Results to Improve its Thermal Efficiency

    NASA Astrophysics Data System (ADS)

    Beemkumar, N.; Karthikeyan, A.; Shiva Keshava Reddy, Kota; Rajesh, Kona; Anderson, A.

    2017-05-01

    The discontinuous temperament of the solar power forces to consider about the energy storage. This work is to analyze the tank, amount of energy stored and its storage time. The thermal and flow analysis has been done by ANSYS with different set temperature values. The experimentation is done for various encapsulating materials with different phase change material (PCM). Findings: The results obtained from experimental work are compared with ANSYS output. The competence of the TES is calculated and further improvements are made to enhance its performance. During charging process the temperature distribution from heat transfer fluid (HTF) to PCM is maximum in copper encapsulations followed by aluminium encapsulations and brass encapsulations. The comparison shows only when the electrical power as an input source. The efficient way of captivating solar energy could be a better replacement for electrical input.

  3. Development of method for experimental determination of wheel-rail contact forces and contact point position by using instrumented wheelset

    NASA Astrophysics Data System (ADS)

    Bižić, Milan B.; Petrović, Dragan Z.; Tomić, Miloš C.; Djinović, Zoran V.

    2017-07-01

    This paper presents the development of a unique method for experimental determination of wheel-rail contact forces and contact point position by using the instrumented wheelset (IWS). Solutions of key problems in the development of IWS are proposed, such as the determination of optimal locations, layout, number and way of connecting strain gauges as well as the development of an inverse identification algorithm (IIA). The base for the solution of these problems is the wheel model and results of FEM calculations, while IIA is based on the method of blind source separation using independent component analysis. In the first phase, the developed method was tested on a wheel model and a high accuracy was obtained (deviations of parameters obtained with IIA and really applied parameters in the model are less than 2%). In the second phase, experimental tests on the real object or IWS were carried out. The signal-to-noise ratio was identified as the main influential parameter on the measurement accuracy. Тhе obtained results have shown that the developed method enables measurement of vertical and lateral wheel-rail contact forces Q and Y and their ratio Y/Q with estimated errors of less than 10%, while the estimated measurement error of contact point position is less than 15%. At flange contact and higher values of ratio Y/Q or Y force, the measurement errors are reduced, which is extremely important for the reliability and quality of experimental tests of safety against derailment of railway vehicles according to the standards UIC 518 and EN 14363. The obtained results have shown that the proposed method can be successfully applied in solving the problem of high accuracy measurement of wheel-rail contact forces and contact point position using IWS.

  4. A method to obtain static potential for electron-molecule scattering

    NASA Astrophysics Data System (ADS)

    Srivastava, Rajesh; Das, Tapasi; Stauffer, Allan

    2014-05-01

    Electron scattering from molecules is complicated by the fact that molecules are a multi-centered target with the nuclei of the constituent atoms being a center of charge. One of the most important parts of a scattering calculation is to obtain the static potential which represents the interaction of the incident electron with the unperturbed charge distribution of the molecule. A common way to represent the charge distribution of molecules is with Gaussian orbitals centered on the various nuclei. We have derived a way to calculate spherically-averaged molecular static potentials using this form of molecular wave function which is mostly analytic. This method has been applied to elastic electron scattering from water molecules and we obtained differential cross sections which are compared with previous experimental and theoretical results. The method can be extended to more complex molecules. One of us (RS) is thankful to IAEA, Vienna, Austria and DAE-BRNS, Mumbai, India for financial support.

  5. Experimental analysis of coding processes.

    PubMed

    Postman, L; Burns, S

    1973-12-01

    The first part of the paper reports an investigation of the effects of the concreteness-imagery (C-I) value of stimuli and responses on the long-term retention of paired-associate lists. With degree of learning equated, the measures of retention after a 1-week interval showed a significant interaction of Stimulus by Response C-I: When the responses had a high value, recall was substantially better with low than with high stimuli; when the responses were low, there was no reliable difference as a function of stimulus value. Recall was best when abstract stimuli were paired with concrete responses. The second part of the paper is addressed to some current issues in the analysis of coding processes. Major emphasis is placed on the experimental and theoretical differentiation of encoding and decoding processes.

  6. The Interpersonal Values of Parents of Normal and Learning Disabled Children.

    ERIC Educational Resources Information Center

    Miletic, Anne

    1986-01-01

    L. Gordon's Survey of Interpersonal Values was used to compare 136 parents of normal and learning disabled children. Fathers of LD boys scored higher on Independence and Leadership and lower on Conformity and Support. Mothers of LD boys favored authoritative attitudes; same-sexed experimental mothers valued conformity and sources of emotional and…

  7. Intrinsically disordered inhibitor of glutamine synthetase is a functional protein with random-coil-like pKa values.

    PubMed

    Cozza, Concetta; Neira, José L; Florencio, Francisco J; Muro-Pastor, M Isabel; Rizzuti, Bruno

    2017-06-01

    The sequential action of glutamine synthetase (GS) and glutamate synthase (GOGAT) in cyanobacteria allows the incorporation of ammonium into carbon skeletons. In the cyanobacterium Synechocystis sp. PCC 6803, the activity of GS is modulated by the interaction with proteins, which include a 65-residue-long intrinsically disordered protein (IDP), the inactivating factor IF7. This interaction is regulated by the presence of charged residues in both IF7 and GS. To understand how charged amino acids can affect the binding of an IDP with its target and to provide clues on electrostatic interactions in disordered states of proteins, we measured the pK a values of all IF7 acidic groups (Glu32, Glu36, Glu38, Asp40, Asp58, and Ser65, the backbone C-terminus) at 100 mM NaCl concentration, by using NMR spectroscopy. We also obtained solution structures of IF7 through molecular dynamics simulation, validated them on the basis of previous experiments, and used them to obtain theoretical estimates of the pK a values. Titration values for the two Asp and three Glu residues of IF7 were similar to those reported for random-coil models, suggesting the lack of electrostatic interactions around these residues. Furthermore, our results suggest the presence of helical structure at the N-terminus of the protein and of conformational changes at acidic pH values. The overall experimental and in silico findings suggest that local interactions and conformational equilibria do not play a role in determining the electrostatic features of the acidic residues of IF7. © 2017 The Protein Society.

  8. Experimental design for evaluating WWTP data by linear mass balances.

    PubMed

    Le, Quan H; Verheijen, Peter J T; van Loosdrecht, Mark C M; Volcke, Eveline I P

    2018-05-15

    A stepwise experimental design procedure to obtain reliable data from wastewater treatment plants (WWTPs) was developed. The proposed procedure aims at determining sets of additional measurements (besides available ones) that guarantee the identifiability of key process variables, which means that their value can be calculated from other, measured variables, based on available constraints in the form of linear mass balances. Among all solutions, i.e. all possible sets of additional measurements allowing the identifiability of all key process variables, the optimal solutions were found taking into account two objectives, namely the accuracy of the identified key variables and the cost of additional measurements. The results of this multi-objective optimization problem were represented in a Pareto-optimal front. The presented procedure was applied to a full-scale WWTP. Detailed analysis of the relation between measurements allowed the determination of groups of overlapping mass balances. Adding measured variables could only serve in identifying key variables that appear in the same group of mass balances. Besides, the application of the experimental design procedure to these individual groups significantly reduced the computational effort in evaluating available measurements and planning additional monitoring campaigns. The proposed procedure is straightforward and can be applied to other WWTPs with or without prior data collection. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. Scalar discrete nonlinear multipoint boundary value problems

    NASA Astrophysics Data System (ADS)

    Rodriguez, Jesus; Taylor, Padraic

    2007-06-01

    In this paper we provide sufficient conditions for the existence of solutions to scalar discrete nonlinear multipoint boundary value problems. By allowing more general boundary conditions and by imposing less restrictions on the nonlinearities, we obtain results that extend previous work in the area of discrete boundary value problems [Debra L. Etheridge, Jesus Rodriguez, Periodic solutions of nonlinear discrete-time systems, Appl. Anal. 62 (1996) 119-137; Debra L. Etheridge, Jesus Rodriguez, Scalar discrete nonlinear two-point boundary value problems, J. Difference Equ. Appl. 4 (1998) 127-144].

  10. Obtaining of High Cr Content Cast Iron Materials

    NASA Astrophysics Data System (ADS)

    Florea, C.; Bejinariu, C.; Carcea, I.; Cimpoesu, N.; Chicet, D. L.; Savin, C.

    2017-06-01

    We have obtained, through the classic casting process, 3 highly chromium-based experimental alloys proposed for replacing the FC 250 classical cast iron in braking applications. Casting was carried out in an induction furnace and cast into moulds made of KALHARTZ 8500 resin casting mixture and HARTER hardener at SC RanCon SRL Iasi. It is known that the microstructure of the cast iron is a combination of martensite with a small amount of residual austenite after the heat treatment of the ingot. In the case of high-alloy chromium alloys, the performance of the material is due to the presence of M7C3 carbides distributed in the iron matrix Resistance to machining and deformation is based on alloy composition and microstructure, while abrasion resistance will depend on properties and wear conditions.

  11. Discrepancies between conformational distributions of a polyalanine peptide in solution obtained from molecular dynamics force fields and amide I' band profiles.

    PubMed

    Verbaro, Daniel; Ghosh, Indrajit; Nau, Werner M; Schweitzer-Stenner, Reinhard

    2010-12-30

    Structural preferences in the unfolded state of peptides determined by molecular dynamics still contradict experimental data. A remedy in this regard has been suggested by MD simulations with an optimized Amber force field ff03* ( Best, R. Hummer, G. J. Phys. Chem. B 2009 , 113 , 9004 - 9015 ). The simulations yielded a statistical coil distribution for alanine which is at variance with recent experimental results. To check the validity of this distribution, we investigated the peptide H-A(5)W-OH, which with the exception of the additional terminal tryptophan is analogous to the peptide used to optimize the force fields ff03*. Electronic circular dichroism, vibrational circular dichroism, and infrared spectroscopy as well as J-coupling constants obtained from NMR experiments were used to derive the peptide's conformational ensemble. Additionally, Förster resonance energy transfer between the terminal chromophores of the fluorescently labeled peptide analogue H-Dbo-A(5)W-OH was used to determine its average length, from which the end-to-end distance of the unlabeled peptide was estimated. Qualitatively, the experimental (3)J(H(N),C(α)), VCD, and ECD indicated a preference of alanine for polyproline II-like conformations. The experimental (3)J(H(N),C(α)) for A(5)W closely resembles the constants obtained for A(5). In order to quantitatively relate the conformational distribution of A(5) obtained with the optimized AMBER ff03* force field to experimental data, the former was used to derive a distribution function which expressed the conformational ensemble as a mixture of polyproline II, β-strand, helical, and turn conformations. This model was found to satisfactorily reproduce all experimental J-coupling constants. We employed the model to calculate the amide I' profiles of the IR and vibrational circular dichroism spectrum of A(5)W, as well as the distance between the two terminal peptide carbonyls. This led to an underestimated negative VCD couplet and an

  12. Experimental Verification of the Theory of Wind-Tunnel Boundary Interference

    NASA Technical Reports Server (NTRS)

    Theodorsen, Theodore; Silverstein, Abe

    1935-01-01

    The results of an experimental investigation on the boundary-correction factor are presented in this report. The values of the boundary-correction factor from the theory, which at the present time is virtually completed, are given in the report for all conventional types of tunnels. With the isolation of certain disturbing effects, the experimental boundary-correction factor was found to be in satisfactory agreement with the theoretically predicted values, thus verifying the soundness and sufficiency of the theoretical analysis. The establishment of a considerable velocity distortion, in the nature of a unique blocking effect, constitutes a principal result of the investigation.

  13. Capacity value of energy storage considering control strategies.

    PubMed

    Shi, Nian; Luo, Yi

    2017-01-01

    In power systems, energy storage effectively improves the reliability of the system and smooths out the fluctuations of intermittent energy. However, the installed capacity value of energy storage cannot effectively measure the contribution of energy storage to the generator adequacy of power systems. To achieve a variety of purposes, several control strategies may be utilized in energy storage systems. The purpose of this paper is to study the influence of different energy storage control strategies on the generation adequacy. This paper presents the capacity value of energy storage to quantitatively estimate the contribution of energy storage on the generation adequacy. Four different control strategies are considered in the experimental method to study the capacity value of energy storage. Finally, the analysis of the influence factors on the capacity value under different control strategies is given.

  14. Investigation on the supercritical CO(2) extraction of the volatile constituents from Juniperus communis obtained under different treatments of the "berries" (cones).

    PubMed

    Chatzopoulou, Paschalina; de Haan, Andre; Katsiotis, Stavros T

    2002-09-01

    The present investigation reports the experimental data a) from the recovery and the composition of the extract under super critical fluid extraction from Juniperus communis L. "berries" (cones), and b) their comparison with those of the essential oil obtained by hydrodistillation. For the extraction of the juniper oil different values of temperature and pressure were applied; furthermore, the degree of comminution of the plant material was also considered - a) integral "berries" and b) comminuted "berries". The quality of the oil recovered from the "berries" by supercritical carbon dioxide extraction was found to be highly dependent on the applied conditions. The comminution affected greatly the oil recovery and consequently the final composition of the extracts. Significant differences were recorded between the supercritical CO(2) extract and the distilled oil, the latter being more enriched in monoterpenoid hydrocarbons.

  15. Everyday value conflicts and integrative complexity of thought.

    PubMed

    Myyry, Liisa

    2002-12-01

    This study examined the value pluralism model in everyday value conflicts, and the effect of issue context on complexity of thought. According to the cognitive manager model we hypothesized that respondents would obtain a higher level of integrative complexity on personal issues that on professional and general issues. We also explored the relations of integrative complexity to value priorities, measured by the Schwartz Value Survey, and to emotional empathy. The value pluralism model was not supported by the data collected from 126 university students from social science, business and technology. The cognitive manager model was partially confirmed by data from females but not from males. Concerning value priorities, more complex respondents had higher regard for self-transcendence values, and less complex respondents for self-enhancement values Emotional empathy was also significantly related to complexity score.

  16. Experimental investigation of the dynamics of a brake shoe

    NASA Astrophysics Data System (ADS)

    Ivanova, T. B.; Erdakova, N. N.; Karavaev, Yu. L.

    2016-12-01

    The experimental stand is described and the results of investigation of the motion of a brake shoe are presented. In the noncritical region, the friction coefficient is determined experimentally. It is shown that its value corresponds to the condition of uniqueness of the solution for construction of this brake shoe. The dynamics observed in the paradoxical-motion region is described.

  17. Interaction between methyl glyoxal and ascorbic acid: experimental and theoretical aspects

    NASA Astrophysics Data System (ADS)

    Banerjee, D.; Koll, A.; Filarowski, A.; Bhattacharyya, S. P.; Mukherjee, S.

    2004-06-01

    The absorption spectral change of methyl glyoxal (MG) due to the interaction with ascorbic acid (AA or Vitamin C) has been investigated using steady-state spectroscopic technique. A plausible explanation for the spectral change has been discussed on the basis of hydrogen bonding interaction between the two interacting species. The equilibrium constant for the complex formation due to hydrogen bonding interaction between MG and AA has been obtained from absorption spectral changes. Ab inito calculations with DFT B3LYP/6/31G (d,p) basis sets have been used to find out the molecular structure of the hydrogen bonded complex. The O⋯H distance found in the OH⋯O hydrogen bond turns out to be quite short (1.974 Å) which is in conformity with the large value of the equilibrium constant determined experimentally.

  18. Undergraduate Teaching of Ideal and Real Fluid Flows: The Value of Real-World Experimental Projects

    ERIC Educational Resources Information Center

    Baldock, Tom E.; Chanson, Hubert

    2006-01-01

    This paper describes the pedagogical impact of real-world experimental projects undertaken as part of an advanced undergraduate fluid mechanics subject at an Australian university. The projects have been organized to complement traditional lectures and introduce students to the challenges of professional design, physical modelling, data collection…

  19. A critical evaluation of the experimental design of studies of mechanism based enzyme inhibition, with implications for in vitro-in vivo extrapolation.

    PubMed

    Ghanbari, F; Rowland-Yeo, K; Bloomer, J C; Clarke, S E; Lennard, M S; Tucker, G T; Rostami-Hodjegan, A

    2006-04-01

    The published literature on mechanism based inhibition (MBI) of CYPs was evaluated with respect to experimental design, methodology and data analysis. Significant variation was apparent in the dilution factor, ratio of preincubation to incubation times and probe substrate concentrations used, and there were some anomalies in the estimation of associated kinetic parameters (k(inact), K(I), r). The impact of the application of inaccurate values of k(inact) and K(I) when extrapolating to the extent of inhibition in vivo is likely to be greatest for those compounds of intermediate inhibitory potency, but this also depends on the fraction of the net clearance of substrate subject to MBI and the pre-systemic and systemic exposure to the inhibitor. For potent inhibitors, the experimental procedure is unlikely to have a material influence on the maximum inhibition. Nevertheless, the bias in the values of the kinetic parameters may influence the time for recovery of enzyme activity following re-synthesis of the enzyme. Careful attention to the design of in vitro experiments to obtain accurate kinetic parameters is necessary for a reliable prediction of different aspects of the in vivo consequences of MBI. The review calls for experimental studies to quantify the impact of study design in studies of MBI, with a view to better harmonisation of protocols.

  20. Entanglement-Assisted Weak Value Amplification

    NASA Astrophysics Data System (ADS)

    Pang, Shengshi; Dressel, Justin; Brun, Todd A.

    2014-07-01

    Large weak values have been used to amplify the sensitivity of a linear response signal for detecting changes in a small parameter, which has also enabled a simple method for precise parameter estimation. However, producing a large weak value requires a low postselection probability for an ancilla degree of freedom, which limits the utility of the technique. We propose an improvement to this method that uses entanglement to increase the efficiency. We show that by entangling and postselecting n ancillas, the postselection probability can be increased by a factor of n while keeping the weak value fixed (compared to n uncorrelated attempts with one ancilla), which is the optimal scaling with n that is expected from quantum metrology. Furthermore, we show the surprising result that the quantum Fisher information about the detected parameter can be almost entirely preserved in the postselected state, which allows the sensitive estimation to approximately saturate the relevant quantum Cramér-Rao bound. To illustrate this protocol we provide simple quantum circuits that can be implemented using current experimental realizations of three entangled qubits.

  1. Experimental verification of propeller noise prediction

    NASA Technical Reports Server (NTRS)

    Succi, G. P.; Munro, D. H.; Zimmer, J. A.

    1980-01-01

    Results of experimental measurements of the sound fields of 1/4-scale general aviation propellers are presented and experimental wake surveys and pressure signatures obtained are compared with theoretical predictions. Experiments were performed primarily on a 1C160 propeller model mounted in front of a symmetric body in an anechoic wind tunnel, and measured the thrust and torque produced by propeller at different rotation speeds and tunnel velocities, wakes at three axial distances, and sound pressure at various azimuths and tip speeds with advance ratio or tunnel velocity constant. Aerodynamic calculations of blade loading were performed using airfoil section characteristics and a modified strip analysis procedure. The propeller was then modeled as an array of point sound sources with each point characterized by the force and volume of the corresponding propeller section in order to obtain the acoustic characteristics. Measurements are found to agree with predictions over a wide range of operating conditions, tip speeds and propeller nacelle combinations, without the use of adjustable constants.

  2. Optimal Experimental Design for Model Discrimination

    ERIC Educational Resources Information Center

    Myung, Jay I.; Pitt, Mark A.

    2009-01-01

    Models of a psychological process can be difficult to discriminate experimentally because it is not easy to determine the values of the critical design variables (e.g., presentation schedule, stimulus structure) that will be most informative in differentiating them. Recent developments in sampling-based search methods in statistics make it…

  3. Parametric and experimental analysis using a power flow approach

    NASA Technical Reports Server (NTRS)

    Cuschieri, J. M.

    1990-01-01

    A structural power flow approach for the analysis of structure-borne transmission of vibrations is used to analyze the influence of structural parameters on transmitted power. The parametric analysis is also performed using the Statistical Energy Analysis approach and the results are compared with those obtained using the power flow approach. The advantages of structural power flow analysis are demonstrated by comparing the type of results that are obtained by the two analytical methods. Also, to demonstrate that the power flow results represent a direct physical parameter that can be measured on a typical structure, an experimental study of structural power flow is presented. This experimental study presents results for an L shaped beam for which an available solution was already obtained. Various methods to measure vibrational power flow are compared to study their advantages and disadvantages.

  4. Lossless and lossy compression of quantitative phase images of red blood cells obtained by digital holographic imaging.

    PubMed

    Jaferzadeh, Keyvan; Gholami, Samaneh; Moon, Inkyu

    2016-12-20

    In this paper, we evaluate lossless and lossy compression techniques to compress quantitative phase images of red blood cells (RBCs) obtained by an off-axis digital holographic microscopy (DHM). The RBC phase images are numerically reconstructed from their digital holograms and are stored in 16-bit unsigned integer format. In the case of lossless compression, predictive coding of JPEG lossless (JPEG-LS), JPEG2000, and JP3D are evaluated, and compression ratio (CR) and complexity (compression time) are compared against each other. It turns out that JP2k can outperform other methods by having the best CR. In the lossy case, JP2k and JP3D with different CRs are examined. Because some data is lost in a lossy way, the degradation level is measured by comparing different morphological and biochemical parameters of RBC before and after compression. Morphological parameters are volume, surface area, RBC diameter, sphericity index, and the biochemical cell parameter is mean corpuscular hemoglobin (MCH). Experimental results show that JP2k outperforms JP3D not only in terms of mean square error (MSE) when CR increases, but also in compression time in the lossy compression way. In addition, our compression results with both algorithms demonstrate that with high CR values the three-dimensional profile of RBC can be preserved and morphological and biochemical parameters can still be within the range of reported values.

  5. Experimental and calculated LET distributions in the Cosmos-2044 biosatellite orbit

    NASA Technical Reports Server (NTRS)

    Watts, J. W., Jr.; Dudkin, V. E.; Karpov, O. N.; Potapov, Yu. V.; Akopova, A. B.; Magradze, N. V.; Moiseenko, A. A.; Benton, E. V.; Frank, A. L.

    1995-01-01

    During the flight of the Cosmos-2044 biosatellite, joint U.S.S.R.-U.S.A. investigations of different characteristics of cosmic radiation (CR) in the near-Earth environment were carried out. The U.S. dielectric track detectors CR-39 and Soviet BYa- and BR-type nuclear photo-emulsions were used as detectors. The present work shows some results of experimental measurements of linear energy transfer (LET) spectra of CR particles obtained with the use of these detectors, which were placed both inside and outside the satellite. The LET spectra measurements with plastic detectors is composed of two parts: the measurement of galactic cosmos rays (GCR) particles, and of short-range particles. The contributions of these components to the total LET distribution at various thicknesses of the shielding were analyzed and the results of these studies are presented. Calculated LET spectra in the Cosmos-2044 orbit were compared with experimental data. On the basis of experimental and calculated values of the LET spectra, absorbed and equivalent CR doses were calculated. In the shielding range of 1-1.5 g cm(exp -2), outside the spacecraft, the photo-emulsions yielded 10.3 mrad d(exp -1) and 13.4 mrem d(exp -1) (LET greater than or equal to 40 MeV cm(exp -1)). Inside the spacecraft (greater than or equal to 10 g cm(exp -2) the photo-emulsions yielded 8.9 mrad d(exp -1) and 14.5 mrem d(exp -1).

  6. Experimental research on air propellers

    NASA Technical Reports Server (NTRS)

    Durand, William F

    1918-01-01

    The purposes of the experimental investigation on the performance of air propellers described in this report are as follows: (1) the development of a series of design factors and coefficients drawn from model forms distributed with some regularity over the field of air-propeller design and intended to furnish a basis of check with similar work done in other aerodynamic laboratories, and as a point of departure for the further study of special or individual types and forms; (2) the establishment of a series of experimental values derived from models and intended for later use as a basis for comparison with similar results drawn from certain selected full-sized forms and tested in free flight.

  7. Experimental trim drag values and flow-field measurements for a wide-body transport model with conventional and supercritical wings

    NASA Technical Reports Server (NTRS)

    Jacobs, P. F.

    1982-01-01

    The purpose of this study was to determine if advanced supercritical wings incur higher trim drag values at cruise conditions than current wide body technology wings. Relative trim drag increments were measured in an experimental wind tunnel investigation conducted in the Langley 8 Foot Transonic Pressure Tunnel. The tests utilized a high aspect ratio supercritical wing and a wide body aircraft wing, in conjunction with five different horizontal tail configurations, mounted on a representative wide body fuselage. The three low tail and two T-tail configurations were designed to measure the effects of horizontal tail size, location, and camber on the trim drag increments for the two wings. Longitudinal force and moment data were taken at a Mach number of 0.82 and design cruise lift coefficients for the wide body and supercritical wings of 0.45 and 0.55, respectively. The data indicate that the supercritical wing does not have significantly higher trim drag than the wide body wing. A reduction in tail size, combined with relaxed static stability, produced trim drag reductions for both wings. The cambered tails had higher trim drag increments than the symmetrical tails for both wings, and the T-tail configurations had lower trim drag increments than the low tail configurations.

  8. Experimental and theoretical study on free 5-nitroquinoline, 5-nitroisoquinoline, and their zinc(II) halide complexes

    NASA Astrophysics Data System (ADS)

    Yurdakul, Şenay; Badoğlu, Serdar; Güleşci, Yeliz

    2015-02-01

    In this study where the interpretations of the experimental IR and Raman spectra recorded at room temperature for the ligands 5-nitroquinoline (5NQ) and 5-nitroisoquinoline (5NIQ) and also for their Zn(II) halide (halogen: chlorine, bromine, iodine) complexes were first reported, the assignments of the observed fundamental bands were achieved in the light of the vibrational spectral data and total energy distribution (TED) values calculated at B3LYP/6-311++G(d,p) and B3LYP/LANL2DZ levels of theory. The equilibrium geometrical parameters, Natural Bond Orbital (NBO) charges and frontier orbital (HOMO, LUMO) energies of these molecular structures were also calculated at the same level of theory. Comparisons over the corresponding experimental and theoretical data obtained for the title ligands and their complexes revealed that in complex form both ligands bond to Zn(II) ion through their ring nitrogen atoms and NO2 groups at the same time.

  9. Characterization of protein folding by a Φ-value calculation with a statistical-mechanical model.

    PubMed

    Wako, Hiroshi; Abe, Haruo

    2016-01-01

    The Φ-value analysis approach provides information about transition-state structures along the folding pathway of a protein by measuring the effects of an amino acid mutation on folding kinetics. Here we compared the theoretically calculated Φ values of 27 proteins with their experimentally observed Φ values; the theoretical values were calculated using a simple statistical-mechanical model of protein folding. The theoretically calculated Φ values reflected the corresponding experimentally observed Φ values with reasonable accuracy for many of the proteins, but not for all. The correlation between the theoretically calculated and experimentally observed Φ values strongly depends on whether the protein-folding mechanism assumed in the model holds true in real proteins. In other words, the correlation coefficient can be expected to illuminate the folding mechanisms of proteins, providing the answer to the question of which model more accurately describes protein folding: the framework model or the nucleation-condensation model. In addition, we tried to characterize protein folding with respect to various properties of each protein apart from the size and fold class, such as the free-energy profile, contact-order profile, and sensitivity to the parameters used in the Φ-value calculation. The results showed that any one of these properties alone was not enough to explain protein folding, although each one played a significant role in it. We have confirmed the importance of characterizing protein folding from various perspectives. Our findings have also highlighted that protein folding is highly variable and unique across different proteins, and this should be considered while pursuing a unified theory of protein folding.

  10. Characterization of protein folding by a Φ-value calculation with a statistical-mechanical model

    PubMed Central

    Wako, Hiroshi; Abe, Haruo

    2016-01-01

    The Φ-value analysis approach provides information about transition-state structures along the folding pathway of a protein by measuring the effects of an amino acid mutation on folding kinetics. Here we compared the theoretically calculated Φ values of 27 proteins with their experimentally observed Φ values; the theoretical values were calculated using a simple statistical-mechanical model of protein folding. The theoretically calculated Φ values reflected the corresponding experimentally observed Φ values with reasonable accuracy for many of the proteins, but not for all. The correlation between the theoretically calculated and experimentally observed Φ values strongly depends on whether the protein-folding mechanism assumed in the model holds true in real proteins. In other words, the correlation coefficient can be expected to illuminate the folding mechanisms of proteins, providing the answer to the question of which model more accurately describes protein folding: the framework model or the nucleation-condensation model. In addition, we tried to characterize protein folding with respect to various properties of each protein apart from the size and fold class, such as the free-energy profile, contact-order profile, and sensitivity to the parameters used in the Φ-value calculation. The results showed that any one of these properties alone was not enough to explain protein folding, although each one played a significant role in it. We have confirmed the importance of characterizing protein folding from various perspectives. Our findings have also highlighted that protein folding is highly variable and unique across different proteins, and this should be considered while pursuing a unified theory of protein folding. PMID:28409079

  11. Vibration and loads in hingeless rotors. Volume 2: Experimental data

    NASA Technical Reports Server (NTRS)

    Watts, G. A.; London, R. J.

    1972-01-01

    Descriptions, geometry, and technical data covering three rotor systems are presented. Tables of experimental data gathered during wind tunnel testing of two of the systems are included. Both analyzed experimental data, ready for comparison with theory, and the basic reduced data from which they were obtained are reported.

  12. Experimental and analytical studies of high heat flux components for fusion experimental reactor

    NASA Astrophysics Data System (ADS)

    Araki, Masanori

    1993-03-01

    In this report, the experimental and analytical results concerning the development of plasma facing components of ITER are described. With respect to developing high heat removal structures for the divertor plates, an externally-finned swirl tube was developed based on the results of critical heat flux (CHF) experiments on various tube structures. As the result, the burnout heat flux, which also indicates incident CHF, of 41 (+/-) 1 MW/sq m was achieved in the externally-finned swirl tube. The applicability of existing CHF correlations based on uniform heating conditions was evaluated by comparing the CHF experimental data with the smooth and the externally-finned tubes under one-sided heating condition. As the results, experimentally determined CHF data for straight tube show good agreement, for the externally-finned tube, no existing correlations are available for prediction of the CHF. With respect to the evaluation of the bonds between carbon-based material and heat sink metal, results of brazing tests were compared with the analytical results by three dimensional model with temperature-dependent thermal and mechanical properties. Analytical results showed that residual stresses from brazing can be estimated by the analytical three directional stress values instead of the equivalent stress value applied. In the analytical study on the separatrix sweeping for effectively reducing surface heat fluxes on the divertor plate, thermal response of the divertor plate was analyzed under ITER relevant heat flux conditions and has been tested. As the result, it has been demonstrated that application of the sweeping technique is very effective for improvement in the power handling capability of the divertor plate and that the divertor mock-up has withstood a large number of additional cyclic heat loads.

  13. Revisiting Grodzins systematics of B(E2) values

    DOE PAGES

    Pritychenko, B.; Birch, M.; Singh, B.

    2017-04-03

    Using Grodzins formalism, we analyze systematics of our latest evaluated B(E2) data for all the even–even nuclei in Z=2–104. The analysis indicates a low predictive power of systematics for a large number of cases, and a strong correlation between B(E2) fit values and nuclear structure effects. These findings provide a strong rationale for introduction of individual or elemental (grouped by Z) fit parameters. The current estimates of quadrupole collectivities for systematics of even–even nuclei yield complementary values for comparison with experimental results and theoretical calculations. Furthermore, the lists of fit parameters and predicted B(E2) values are given and possible implicationsmore » are discussed.« less

  14. Experimental study and empirical prediction of fuel flow parameters under air evolution conditions

    NASA Astrophysics Data System (ADS)

    Kitanina, E. E.; Kitanin, E. L.; Bondarenko, D. A.; Kravtsov, P. A.; Peganova, M. M.; Stepanov, S. G.; Zherebzov, V. L.

    2017-11-01

    Air evolution in kerosene under the effect of gravity flow with various hydraulic resistances in the pipeline was studied experimentally. The study was conducted at pressure ranging from 0.2 to 1.0 bar and temperature varying between -20°C and +20°C. Through these experiments, the oversaturation limit beyond which dissolved air starts evolving intensively from the fuel was established and the correlations for the calculation of pressure losses and air evolution on local loss elements were obtained. A method of calculating two-phase flow behaviour in a titled pipeline segment with very low mass flow quality and fairly high volume flow quality was developed. The complete set of empirical correlations obtained by experimental analysis was implemented in the engineering code. The software simulation results were repeatedly verified against our experimental findings and Airbus test data to show that the two-phase flow simulation agrees quite well with the experimental results obtained in the complex branched pipelines.

  15. [Morphometric and stereologic nuclear values obtained from the study of a population suffering from nasopharyngeal carcinoma].

    PubMed

    Pérez Plasencia, D; Flores Corral, T; Urrutia Avisrror, M; Santa Cruz Ruiz, S; Benito González, J; Mateos Pérez, M M; Gómez González, J L

    2002-01-01

    Computer nuclear morphometry and stereology are attractive methods because its objectivity and cheapness allowing histologic diagnosis when identifying minimal variations respectively the normality and also detect negligible disparities between anormal cells which could escape to the assessment of the pathologist. We present the data gained from several morphogenic and stereologic parameters resulting of measurements of tumoral cells procured from 40 patients with nasopharyngeal carcinomata. Middle values have been: nuclear area 27.70 microns 2; nuclear perimeter 20.80 microns; nuclear factor of form 0.81 microns; nuclear outline index 4.01; nuclear orientation angle 87.29 degrees; nuclear ellipsiticity 704.14; nuclear regularity 61.83; middle lineal length 4.30, middle linear distance 107.94; and nuclear volume 118.80 microns 3. Our series is the largest studied till now of all found in the literature. Comparison our data with those of previous publications.

  16. Stochastic modeling of experimental chaotic time series.

    PubMed

    Stemler, Thomas; Werner, Johannes P; Benner, Hartmut; Just, Wolfram

    2007-01-26

    Methods developed recently to obtain stochastic models of low-dimensional chaotic systems are tested in electronic circuit experiments. We demonstrate that reliable drift and diffusion coefficients can be obtained even when no excessive time scale separation occurs. Crisis induced intermittent motion can be described in terms of a stochastic model showing tunneling which is dominated by state space dependent diffusion. Analytical solutions of the corresponding Fokker-Planck equation are in excellent agreement with experimental data.

  17. Convergence in parameters and predictions using computational experimental design.

    PubMed

    Hagen, David R; White, Jacob K; Tidor, Bruce

    2013-08-06

    Typically, biological models fitted to experimental data suffer from significant parameter uncertainty, which can lead to inaccurate or uncertain predictions. One school of thought holds that accurate estimation of the true parameters of a biological system is inherently problematic. Recent work, however, suggests that optimal experimental design techniques can select sets of experiments whose members probe complementary aspects of a biochemical network that together can account for its full behaviour. Here, we implemented an experimental design approach for selecting sets of experiments that constrain parameter uncertainty. We demonstrated with a model of the epidermal growth factor-nerve growth factor pathway that, after synthetically performing a handful of optimal experiments, the uncertainty in all 48 parameters converged below 10 per cent. Furthermore, the fitted parameters converged to their true values with a small error consistent with the residual uncertainty. When untested experimental conditions were simulated with the fitted models, the predicted species concentrations converged to their true values with errors that were consistent with the residual uncertainty. This paper suggests that accurate parameter estimation is achievable with complementary experiments specifically designed for the task, and that the resulting parametrized models are capable of accurate predictions.

  18. Experimental and numerical investigation of thermal radiator performances as a source of heat energy in design of dryer simulation

    NASA Astrophysics Data System (ADS)

    Wiryanta, I. K. E. H.; Adiaksa, I. M. A.

    2018-01-01

    The purposes of this research was to investigate the temperature performance of tube and fins car radiator experimentally and numerically. The experiment research was carried out on a simulation design consists of a reservoir water tank, a heater, pump to circulate hot water to the radiator and a cooling fan. The hot water mass flow rate is 0.486 kg/s, and the cooling air velocity of the fan is 1 m/s. The heat transfer rate and the effectiveness of radiator were investigated. The results showed that the exhaust heat transfer rate from the radiator tended to increase over time, with an average heat transfer rate of 3974.3 Watt. The maximum heat transfer rate was 4680 Watt obtained at 6 minutes. The effectiveness of the radiator (ε) over time tends to increase with an average of ε = 0.3 and the maximum effectiveness value was obtained at 12 minutes i.e. 0.35. The numerical research conducted using CFD method. The geometry and meshing created using ANSYS Workbench and the post processing using Fluent. The simulation result showed the similarity with the experimental research. The temperatures of air-side radiator are about 45°C.

  19. Personal and professional values held by baccalaureate nursing students.

    PubMed

    Kaya, Hülya; Işik, Burçin; Şenyuva, Emine; Kaya, Nurten

    2017-09-01

    Values are ideals and beliefs that individuals and groups uphold and lie at the core of the diverse world of human behaviour and are expressed in every human decision and action, both consciously and unconsciously. They represent basic beliefs of what is right, good or desirable and motivate both personal and professional behaviour. In the context of nursing profession, values are essential in order to maintain high standards of the nursing care. This study was planned to examine changes in nursing students' personal and professional values between entering and graduating from an undergraduate nursing programme. Ethical considerations: Measures to protect participants included obtaining Deaconship of Nursing Faculty approval, obtaining signed informed consent and maintaining confidentiality. This study was designed as longitudinal quality. The research population included 143 students registered at a first grade of a nursing faculty for the 2009-2010 academic year. Data were collected with a Questionnaire Form, the Value Preferences Scale, the Professional Values Precedence Scale and the Nursing Professional Values Scale. According to the results, social values have statistical differences in 4-year nursing education. Nursing students in second class have higher score in terms of social values than those in third class. Also, majority of students ranked human dignity as first and justice as second and third from first to fourth classes, and they have very high scores on Nursing Professional Values Scale and its subscales and stated that all items of Nursing Professional Values Scale are very important. As a result, nursing education has vital role in acquiring and maintaining professional values.

  20. Experimental design methods for bioengineering applications.

    PubMed

    Keskin Gündoğdu, Tuğba; Deniz, İrem; Çalışkan, Gülizar; Şahin, Erdem Sefa; Azbar, Nuri

    2016-01-01

    Experimental design is a form of process analysis in which certain factors are selected to obtain the desired responses of interest. It may also be used for the determination of the effects of various independent factors on a dependent factor. The bioengineering discipline includes many different areas of scientific interest, and each study area is affected and governed by many different factors. Briefly analyzing the important factors and selecting an experimental design for optimization are very effective tools for the design of any bioprocess under question. This review summarizes experimental design methods that can be used to investigate various factors relating to bioengineering processes. The experimental methods generally used in bioengineering are as follows: full factorial design, fractional factorial design, Plackett-Burman design, Taguchi design, Box-Behnken design and central composite design. These design methods are briefly introduced, and then the application of these design methods to study different bioengineering processes is analyzed.