Assessment of Accelerated Acquisition of Defense Programs

DTIC Science & Technology

2016-09-01

I N S T I T U T E F O R D E F E N S E A N A L Y S E S Assessment of Accelerated Acquisition of Defense Programs Richard H. Van Atta R. Royce...Defense for Acquisition . The views, opinions, and findings should not be construed as representing the official position of either the Department of...S T I T U T E F O R D E F E N S E A N A L Y S E S IDA Paper P-8161 Assessment of Accelerated Acquisition of Defense Programs Richard H. Van Atta

Research and the Bernard van Leer Foundation.

ERIC Educational Resources Information Center

Wall, W. D.

1978-01-01

Outlines Bernard van Leer Foundation sponsorship of action programs and research studies of child development in 25 countries. The problems and possibilities of such work are discussed from the viewpoint of evaluation and the contribution which can be made to the behavioral sciences--notably to comparative child development. (Author/RH)

Current Programme 1993.

ERIC Educational Resources Information Center

Bernard Van Leer Foundation, The Hague (Netherlands).

This 1993 program report profiles the Bernard van Leer Foundation, a private institution based in The Netherlands that concentrates its resources on support for early childhood development. The first two sections provide a general description of the Bernard van Leer Foundation and its work. The third and fourth sections are the foundation's annual…

Bernard van Leer Foundation Newsletter, 1996.

ERIC Educational Resources Information Center

Bernard van Leer Foundation, Newsletter, 1996

1996-01-01

This document consists of the four issues of the Bernard van Leer Foundation's "Newsletter" published during 1996. The newsletter covers topics related to, or about efforts to foster, the education and welfare of children around the world, and includes descriptions of programs around the world, lists of resources and publications, and…

Polarization Effects in the Luminescence of Cadmium Selenide Electrodes.

DTIC Science & Technology

1983-09-29

UWIS/DC/TR-83/3 Polarization Effects in the Luminescence of Cadmium Selenide Electrodes by Holger H. Streckert, Hal Van Ryswyk, Richard N. Biagioni ...Streckert, Hal Van Ryswyk, N00014-78-C-0633 Richard N. Biagioni and Arthur B. Ellis 9PEFRIGOGNZTNNAEADADDRESS 10. PROGRAM ELEMENT. PROJECT, TASKS

Learning Styles versus the Rip Van Winkle Syndrome.

ERIC Educational Resources Information Center

Orsak, Lana

1990-01-01

Rip Van Winkle would not recognize Corsicana (Texas) High School since its curriculum coordinator began implementing learning styles techniques in various pilot programs. Lecturing to rows of bored students has been replaced by students' active involvement in group activities, listening centers, and tactile/kinesthetic exercises on the floor or at…

The Wim Van Leer Competition for Young Film Makers at the Jerusalem Film Festival.

ERIC Educational Resources Information Center

Mendel, Gilli

1999-01-01

Describes the Jerusalem Film Center and the background, history, and organization of the Wim Van Leer Competition which was established for young filmmakers in high school. Describes the Jerusalem Film Festival, film studies programs at Israeli high schools, and future possibilities. (Author/LRW)

Astronaut James D. van Hoften examines student experiment on Challenger

NASA Image and Video Library

1984-04-15

41C-05-188 (12 April 1984) --- Astronaut James D. van Hoften, mission specialist, holds an aluminum box, full of honeybees. The experiment in Earth-orbit is duplicated with another colony of the young honeycomb builders on Earth. Dan Poskevich submitted the experiment to NASA as part of the Shuttle student involvement program.

77 FR 12246 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-29

... under USFWS's now-discontinued program, are considered non-essential experimental populations. The black... daylight hours. Additional methodological detail is available in VanBlaricom, 1993 and VanBlaricom et al..., 1987). The non-breeding distribution extends from Baja California north to Alaska for males, and...

Simon van der Meer (1925-2011):. A Modest Genius of Accelerator Science

NASA Astrophysics Data System (ADS)

Chohan, Vinod C.

2011-02-01

Simon van der Meer was a brilliant scientist and a true giant of accelerator science. His seminal contributions to accelerator science have been essential to this day in our quest for satisfying the demands of modern particle physics. Whether we talk of long base-line neutrino physics or antiproton-proton physics at Fermilab or proton-proton physics at LHC, his techniques and inventions have been a vital part of the modern day successes. Simon van der Meer and Carlo Rubbia were the first CERN scientists to become Nobel laureates in Physics, in 1984. Van der Meer's lesserknown contributions spanned a whole range of subjects in accelerator science, from magnet design to power supply design, beam measurements, slow beam extraction, sophisticated programs and controls.

Risk Perceptions That Effect Behavior and Attitudes in Safety Programs

DTIC Science & Technology

2004-01-01

Turner, B.A. (1978), Man-made Disasters. London, Wykeham. Van Manen , Max. 1990. Reasearching lived experience: Human Science for an Action Sensitive Pedagogy. New York: State University of New York. ...method employed tried to capture the “essence” of lived experiences, which may have an impact on aviation safety. In Max Van Manen’s book

Research Issues and Language Program Direction. Issues in Language Program Direction: A Series of Annual Volumes.

ERIC Educational Resources Information Center

Heilenman, L. Kathy, Ed.

This collection of papers is divided into two parts. After "Introduction" (L. Kathy Heilenman), Part 1, "Research and Language Program Directors: The Relationship," includes "Research Domains and Language Program Direction" (Bill VanPatten); "Language Program Direction and the Modernist Agenda" (Celeste…

Beyond Child Survival: Towards a New Future. Report of the Bernard van Leer Foundation, 1986-1987.

ERIC Educational Resources Information Center

Bernard Van Leer Foundation, The Hague (Netherlands).

This report on the Bernard van Leer Foundation's early childhood grant program of 1986-1987 is organized by geographic region. Regional sections cover Africa, Asia and the Pacific, Europe, and the Western Hemisphere. Each regional section contains an introduction, a table of major projects being supported in the region, and feature articles on…

Mt. Druitt Early Childhood Project. Third, Fourth, and Fifth Annual Reports to Bernard Van Leer Foundation.

ERIC Educational Resources Information Center

Macquarie Univ., North Ryde (Australia). School of Education.

This series of the third, fourth, and fifth annual reports to the Bernard Van Leer Foundation on the Mt. Druitt Early Childhood Project of Macquarie University, Australia, describes the general activities, program developments, and research activities of the project for the period 1977-1979. The main objective of the project is to develop,…

The Impact of a One to One Laptop Program on the Self-Efficacy of Nine Middle School Students with Specific Learning Disabilities

ERIC Educational Resources Information Center

Steiner, Adam

2017-01-01

A significant body of research has examined the impact of technology on pedagogy (Cuban, 1999; Enyedy, 2014), student achievement (Schachter, 1999; Cheung & Slavin, 2013, OECD, 2015), and equity (Reich, Murnane & Willett, 2012; Van Deursen & Van Dijk, 2011) with both positive and negative results within each domain. Research has also…

A manual for using the highway noise analysis program "Noisesim".

DOT National Transportation Integrated Search

1971-01-01

Noisesim was developed under a National Cooperative Highway Research Program study by Boilt, Beranek and Newman of Van Nuys, California. According to the NCHRP, Virginia was the first state to implement this program and utilize the findings for predi...

Van Kampen Colimits as Bicolimits in Span

NASA Astrophysics Data System (ADS)

Heindel, Tobias; Sobociński, Paweł

The exactness properties of coproducts in extensive categories and pushouts along monos in adhesive categories have found various applications in theoretical computer science, e.g. in program semantics, data type theory and rewriting. We show that these properties can be understood as a single universal property in the associated bicategory of spans. To this end, we first provide a general notion of Van Kampen cocone that specialises to the above colimits. The main result states that Van Kampen cocones can be characterised as exactly those diagrams in ℂ that induce bicolimit diagrams in the bicategory of spans mathcal{S}pan_{mathbb{C}}, provided that ℂ has pullbacks and enough colimits.

Obituary: James Alfred Van Allen, 1914-2006

NASA Astrophysics Data System (ADS)

Ludwig, George H.; McIlwain, Carl Edwin

2006-12-01

James Alfred Van Allen, world-renowned space scientist, died 9 August 2006 at the age of ninety-one. He succumbed to heart failure after a ten-week period of declining health. Van Allen served for his entire sixty-seven-year professional career as an amazingly productive researcher, space science spokesman, inspired teacher, and valued colleague. The realization by him and his associates that charged particles are trapped by the Earth's magnetic field began a whole new field of research, magnetospheric physics. Following that initial discovery, he and his associates quickly extended their observations, first to the inner planets, and then to the rest of the planets and beyond. During his tenure at Iowa, he and his group flew instruments on more than sixty successful Earth satellites and planetary spacecraft, including the first missions to the planets Venus, Mars, Jupiter, Saturn, Uranus, and Neptune. Van Allen's lifetime publication list numbers more than 275, of which many are widely-cited, seminal papers. He was the sole author of more than 125 of those papers. Beyond the research laboratory, Van Allen worked energetically throughout his career in establishing space research as a new branch of human inquiry. He was among the most sought-after as a committee member and adviser, working at the highest levels of government, including the White House and Congress, and at all levels of the national and international research establishments. Many presentations in the non-scientific arena helped to bring the exciting discoveries and challenges of space research to the attention of the general public. James Van Allen (Van to his many friends and colleagues) was born on 7 September 1914 on a small farm near Mount Pleasant, Iowa, the second of four sons of Alfred Morris Van Allen and Alma Olney Van Allen. After high school in Mount Pleasant, he entered Iowa Wesleyan College, majoring in physics and graduating summa cum laude. While there, he was introduced to geophysics research under the tutelage of physics professor Thomas C. Poulter, who served as chief scientist on the 1933-1935 Second Byrd Antarctic Expedition. He entered the State University of Iowa for his graduate work in physics, receiving his master's degree in solid state physics in 1936 and his Ph.D. degree in nuclear physics in 1939. Van Allen's first post-graduate work was as a Carnegie Research Fellow at the Department of Terrestrial Magnetism (DTM) of the Carnegie Institution, located in Washington, DC. There, he was involved in the department's work on nuclear physics, geomagnetism, cosmic rays, auroral physics, and ionospheric physics. By late 1939, the war in Europe was escalating, and Van Allen shifted to development of the embryonic proximity fuse, continuing that work in the Applied Physics Laboratory (APL) that was established for that purpose in 1942. Van Allen and two colleagues took the first of the then highly secret radio proximity fuses to the South Pacific Fleet for initial field trials and introduction into combat. Following the war, Van Allen organized the High Altitude Research Group at APL and directed it until his departure in1950. Among other things, he participated in the planning and use of captured German V-2 rockets. As that program was closing, he led the development of the Aerobee sounding rocket to meet the need for continuing high altitude research. The Aerobee achieved a remarkable record of achievement, with a total of 1,037 fired as of January 1985. As the 1950s opened, Van Allen and his family moved to Iowa City, where he became Professor and Head of the State University of Iowa Physics Department. He and his new graduate students started a research program by using the university's football practice field to launch cosmic ray instruments with small surplus balloons. That quickly expanded to the use of rockets to carry larger balloons to greater heights. Those "rockoons," a Van Allen invention, were launched from a series of six highly successful field expeditions from 1952 through 1957. As the prospect for launching Earth satellites began to materialize, Van Allen became an enthusiastic participant in planning and executing the U.S. program. After gaining a spot on the short list of initial experiments for the Vanguard satellite program, development of the cosmic ray instrument that he had proposed became a high laboratory priority. That instrument was launched in abbreviated form by an Army Jupiter C vehicle as Explorer I on 31 January 1958, and the full version was launched less than two months later as Explorer III. The two satellites resulted in what Van Allen considered the crowning event of his long and distinguished career — the discovery, with his university associates, of the bands of intense radiation that surround the Earth, now known as the "Van Allen Radiation Belts." Van Allen continued to take a leading role in extending space research beyond Earth's orbit. His group sent instruments to the Moon, Venus, Mars, Jupiter, Saturn, and throughout interplanetary space. During his outstandingly productive career, Van Allen served as principal investigator on more than twenty-five space science missions. James Van Allen was the consummate teacher and mentor. Years ago, when asked how he would most like to be remembered, he replied simply, "As a teacher." He supervised the preparation of forty-eight master's and thirty-four doctor's theses by sixty different individuals. He gave those graduate students extraordinary freedom and responsibility in the conduct of their projects. He always treated his students, both undergraduate and graduate, with respect, listening to them, learning from them, and guiding them with wisdom and kindness. The folksy, pipe-smoking scientist worked from 1951 until 1964 in a modest office on the second floor of the old Physics and Mathematics building. He maintained his own private laboratory, where he continued to spend many hours with hands-on work at the bench. When the new Physics and Astronomy building was completed in 1964 (rechristened in 1982, appropriately, as Van Allen Hall), he set up his private working room apart from his departmental office in a large, soon-cluttered, corner office on the seventh floor. That room became the center of his activity in 1985, when he retired as Department Head and active teacher. There, through his retirement years and until shortly before his death, he continued his roles as researcher, advisor, and mentor, serving at times as Professor Emeritus, Carver Professor of Physics, and Regent Distinguished Professor. Van Allen maintained membership in over a dozen professional organizations and received over a dozen Honorary ScD degrees. His additional awards and other distinct forms of recognition are far too numerous to list here, but include AAS's Gerard P. Kuiper Prize, the Crafoord Prize of the Royal Swedish Academy of Science, the National Medal of Science presented by U.S. President Reagan, the National Science Foundation's Vannevar Bush Award, NASA's Lifetime Achievement Award, the 2006 Smithsonian National Air and Space Museum Lifetime Achievement Trophy, the Gold Medal of the Royal Astronomy Society, AGU's John A. Fleming Award and William Bowie Medal, and the Abelson Prize by the American Association for the Advancement of Science. In addition to those many public acknowledgements of his prodigious contributions, James A. Van Allen will be fondly remembered by his many students, who now populate the entire realm of modern space research. He is survived by his wife, Abigail Fithian Halsey II Van Allen, and his five children, Cynthia Van Allen Schaffner, Dr. Margot Van Allen Cairns, Sarah Van Allen Trimble, Thomas Halsey Van Allen, and Peter C. Van Allen.

77 FR 10718 - Request for Proposals: 2012 Hazardous Fuels Woody Biomass Utilization Grant Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-23

... DEPARTMENT OF AGRICULTURE Forest Service Request for Proposals: 2012 Hazardous Fuels Woody Biomass Utilization Grant Program AGENCY: Forest Service, USDA. ACTION: Notice; Correction. SUMMARY: The Department of... Biomass Coordinator as listed in the addresses above or contact Susan LeVan-Green, Program Manager of the...

Library Programs. Evaluating Federally Funded Public Library Programs.

ERIC Educational Resources Information Center

Office of Educational Research and Improvement (ED), Washington, DC.

Following an introduction by Betty J. Turock, nine reports examine key issues in library evaluation: (1) "Output Measures and the Evaluation Process" (Nancy A. Van House) describes measurement as a concept to be understood in the larger context of planning and evaluation; (2) "Adapting Output Measures to Program Evaluation"…

DOE/KEURP site operator program. Year 3, Second Quarter Report, October 1--December 31, 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Kansas State University, with funding support from federal, state, public, and private companies, is participating in the Department of Energy`s Electric Vehicle Site Operator Program. Through participation in this program, Kansas State is displaying, testing, and evaluating electric or hybrid vehicle technology. This participation will provide organizations the opportunity to examine the latest EHV prototypes under actual operating conditions. KSU has purchased several electric cars and proposes to purchase additional electric vehicles. KSU has purchased one G-Van built by Conceptor Industries, Toronto, Canada and has procured two (2) Soleq 1993 Ford EVcort station wagons. During calendar year 1994, the Kansas`more » electric vehicle program expects to purchase a minimum of four and a maximum of eleven additional electric vehicles. The G-Van was signed in order for the public to be aware that it was an electric vehicle. Financial participants` names have been stenciled on the back door of the van. The Soleq EvCorts have not been signed. In order to demonstrate the technology as feasible, the EvCorts were deliberately not signed. The goal is to generate a public perception that this vehicle is no different from any similar internal combustion engine vehicle. Magnetic signs have been made for special functions to ensure sponsor support is recognized and acknowledged.« less

Eindrapportage doelfinancieringsgrogramma V910 Munitie: functionering, veiligheid en milieu (Final Report of Program V910 Munition: Functioning, Safety and Environmental Aspects)

DTIC Science & Technology

2005-09-01

kEuro. De doeistellingen van ditprogranxnu zijn in der tijd ais volgt ornscbreven. Defensiedoelstelling Het prograruma beeft tot doe] de Kennis Kunde en...typeklassificatie en kwalificatieprocedure in Nederland is achterhaald; genoemde organisatie en functionarissen bijvoorbeeld dienen bij de tijd te...voorzien is van een kunststof coating waaraan de te analyseren stof adsorbeert. Deze vezel wordt vervolgens gedurende enige tijd in contact gebracht

Supporting Universal Prevention Programs: A Two-Phased Coaching Model

ERIC Educational Resources Information Center

Becker, Kimberly D.; Darney, Dana; Domitrovich, Celene; Keperling, Jennifer Pitchford; Ialongo, Nicholas S.

2013-01-01

Schools are adopting evidence-based programs designed to enhance students' emotional and behavioral competencies at increasing rates (Hemmeter et al. in "Early Child Res Q" 26:96-109, 2011). At the same time, teachers express the need for increased support surrounding implementation of these evidence-based programs (Carter and Van Norman in "Early…

Whatever Happened to Richard Reid's List of First Programming Languages?

ERIC Educational Resources Information Center

Siegfried, Robert M.; Greco, Daniel M.; Miceli, Nicholas G.; Siegfried, Jason P.

2012-01-01

Throughout the 1990s, Richard Reid of Michigan State University maintained a list showing the first programming language used in introductory programming courses taken by computer science and information systems majors; it was updated for several years afterwards by Frances Van Scoy of West Virginia University. However, it has been 5 years since…

Maximizing School Guidance Program Effectiveness: A Guide for School Administrators & Program Directors.

ERIC Educational Resources Information Center

Dykeman, Cass, Ed.

Twenty-three brief chapters provide administrators a comprehensive guide to school counseling that describes practices, problems, and processes for which school counselors' expertise may be relied on. Chapters are: (1) "Comprehensive School Counseling Programs" (Z. VanZandt, K. H. Burke, M. J. DeRespino); (2) "The Elementary School Counseling…

Documentation of the data analysis system for the gamma ray monitor aboard OSO-H

NASA Technical Reports Server (NTRS)

Croteau, S.; Buck, A.; Higbie, P.; Kantauskis, J.; Foss, S.; Chupp, D.; Forrest, D. J.; Suri, A.; Gleske, I.

1973-01-01

The programming system is presented which was developed to prepare the data from the gamma ray monitor on OSO-7 for scientific analysis. The detector, data, and objectives are described in detail. Programs presented include; FEEDER, PASS-1, CAL1, CAL2, PASS-3, Van Allen Belt Predict Program, Computation Center Plot Routine, and Response Function Programs.

Ambient noise levels in mobile audiometric testing facilities: compliance with industry standards.

PubMed

Lankford, J E; Perrone, D C; Thunder, T D

1999-04-01

Excessive ambient noise levels in audiometric test booths may elevate and therefore invalidate hearing thresholds of employees included in a hearing conservation program. This study was conducted to determine if a sample of mobile test vans and trailers operating in the Midwest met the 1983 Occupational Safety and Health Administration (OSHA) maximum permissible ambient noise levels (MPANLs), the MPANLs in the American National Standards Institute (ANSI) S3.1-1991, and the suggested National Hearing Conservation Association (NHCA) values. Ambient noise levels were measured in 13 audiometric test booths contained in 12 different industrial mobile test vans and trailers operating in the Midwest. Results indicated that all 13 (100%) of the industrial mobile test vans and trailers evaluated complied with 1983 OSHA permissible levels and the NHCA 1996 recommended levels. With regard to the 1991 ANSI MPANLs, 5 (38%) of the 13 booths were in compliance at all frequencies. Those that failed did so at 125, 250, and 500 Hz. It appears that the NHCA levels need to be used for all hearing conservation programs with respect to compliance for noise levels in mobile audiometric test booths.

Programming for Adolescents with Behavioral Disorders.

ERIC Educational Resources Information Center

Braaten, Sheldon, Ed.; And Others

This book presents 17 papers from a 1982 national multidisciplinary conference on services for behaviorally disordered adolescents. The following papers are included: "Programming for Youth in Secondary Schools and the Community," (W. Van Til); "Who's Crazy? II" (C. Michael Nelson); "Correlates of Successful Adaptive Behavior: Comparative Studies…

A High School-Collegiate Outreach Program in Chemistry and Biology Delivering Modern Technology in a Mobile Van

NASA Astrophysics Data System (ADS)

Craney, Chris; Mazzeo, April; Lord, Kaye

1996-07-01

During the past five years the nation's concern for science education has expanded from a discussion about the future supply of Ph.D. scientists and its impact on the nation's scientific competitiveness to the broader consideration of the science education available to all students. Efforts to improve science education have led many authors to suggest greater collaboration between high school science teachers and their college/university colleagues. This article reviews the experience and outcomes of the Teachers + Occidental = Partnership in Science (TOPS) van program operating in the Los Angeles Metropolitan area. The program emphasizes an extensive ongoing staff development, responsiveness to teachers' concerns, technical and on-site support, and sustained interaction between participants and program staff. Access to modern technology, including computer-driven instruments and commercial data analysis software, coupled with increased teacher content knowledge has led to empowerment of teachers and changes in student interest in science. Results of student and teacher questionnaires are reviewed.

NOAA Photo Library - Meet the Photographers/Dr. Michael Van Woert

Science.gov Websites

, California. In January 1993 he assumed duties as the program scientist for the NASA TOPEX/POSEIDON altimeter mission and program manager for the Physical Oceanography Program at NASA Headquarters. The only snow and ice he encountered during the two years at NASA was above average winter snowfall on the streets of

Optimized production and characterization of a detergent-stable protease from Lysinibacillus fusiformis C250R.

PubMed

Mechri, Sondes; Kriaa, Mouna; Ben Elhoul Berrouina, Mouna; Omrane Benmrad, Maroua; Zaraî Jaouadi, Nadia; Rekik, Hatem; Bouacem, Khelifa; Bouanane-Darenfed, Amel; Chebbi, Alif; Sayadi, Sami; Chamkha, Mohamed; Bejar, Samir; Jaouadi, Bassem

2017-08-01

In this study, we aimed to optimize the cultural and nutritional conditions for protease production by Lysinibacillus fusiformis strain C250R in submerged fermentation process using statistical methodology. The most significant factors (gruel, wheat bran, yeast extract, and FeSO 4 ) were identified by Plackett-Burman design. Response surface methodology (RSM) was used to determine the optimum levels of the screened factors and their interaction. Under the optimized conditions, protease yield 3100U/mL was 4.5 folds higher than those obtained by the use of the initial conditions (680U/mL). Additionally, a new extracellular 51kDa-protease, designated SAPLF, was purified and biochemically characterized from strain C250R. It shows optimum activity at 70°C and pH 10. Its half-life times at 70 and 80°C were 10 and 6-h, respectively. Irreversible inhibition of enzyme activity of SAPLF with serine protease inhibitors demonstrated that it belongs to the serine protease family. Interestingly, its catalytic efficiency was higher than that of SPVP from Aeribacillus pallidus strain VP3 and Alcalase Ultra 2.5L from Bacillus licheniformis. This study demonstrated that SAPLF has a high detergent compatibility and an excellent stain removal compared to Alcalase Ultra 2.5L; which offers an interesting potential for its application in the laundry detergent industry. Copyright © 2017 Elsevier B.V. All rights reserved.

Mammograms on-the-go-predictors of repeat visits to mobile mammography vans in St Louis, Missouri, USA: a case-control study.

PubMed

Drake, Bettina F; Abadin, Salmafatima S; Lyons, Sarah; Chang, Su-Hsin; Steward, Lauren T; Kraenzle, Susan; Goodman, Melody S

2015-03-20

Among women, breast cancer is the most common non-cutaneous cancer and second most common cause of cancer-related death. The purpose of this study was to determine the extent to which women use mobile mammography vans for breast cancer screening and what factors are associated with repeat visits to these vans. A case-control study. Cases are women who had a repeat visit to the mammography van. (n=2134). Women who received a mammogram as part of Siteman Cancer Center's Breast Health Outreach Program responded to surveys and provided access to their clinical records (N=8450). Only visits from 2006 to 2014 to the mammography van were included. The main outcome is having a repeat visit to the mammography van. Among the participants, 25.3% (N=2134) had multiple visits to the mobile mammography van. Data were analysed using χ(2) tests, logistic regression and negative binomial regression. Women who were aged 50-65, uninsured, or African-American had higher odds of a repeat visit to the mobile mammography van compared with women who were aged 40-50, insured, or Caucasian (OR=1.135, 95% CI 1.013 to 1.271; OR=1.302, 95% CI 1.146 to 1.479; OR=1.281, 95% CI 1.125 to 1.457), respectively. However, the odds of having a repeat visit to the van were lower among women who reported a rural ZIP code or were unemployed compared with women who provided a suburban ZIP code or were employed (OR=0.503, 95% CI 0.411 to 0.616; OR=.868, 95% CI 0.774 to 0.972), respectively. This study has identified key characteristics of women who are either more or less likely to use mobile mammography vans as their primary source of medical care for breast cancer screening and have repeat visits. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Freedom to act fast.

NASA Technical Reports Server (NTRS)

Pickering, W. H.

1972-01-01

The history of the development program that culminated in the Explorer and Pioneer launchings is outlined. Earlier work on launching rockets, and the discovery of the Van Allen belts is discussed. The Explorer program was carried out in less than three months, and the different Explorers launched later carried widely different payloads.

Teaching Language Concepts to Multihandicapped Deaf Students.

ERIC Educational Resources Information Center

Brasch, Marilyn; Boespflug, Pam

This brief paper offers suggestions for parents and teachers working together to develop meaningful communication skills in deaf multihandicapped children. An intervention program developed by Jan VanDijk is described. This program involves the use of environmental engineering to teach language concepts with materials such as a calendar box with…

Veggie Van Pilot Study: Impact of a Mobile Produce Market for Underserved Communities on Fruit and Vegetable Access and Intake

PubMed Central

Leone, Lucia A.; Haynes-Maslow, Lindsey; Ammerman, Alice S.

2016-01-01

We conducted a pilot evaluation of the Veggie Van, a mobile produce market that brings weekly boxes of reduced-cost locally grown fruits and vegetables (F&V) to lower-income communities and offers cooking and nutrition education to customers. We conducted surveys just prior to starting Veggie Van at each of 3 sites and again at 2–3 months. F&V intake was measured with a 2-question item and a 10-item food frequency questionnaire (FFQ) in a subset of participants. At baseline, average servings/day of F&V was 4.9 (SD = 2.6, n = 60). At follow-up, individuals who reported shopping at Veggie Van frequently (n = 32) increased their F&V consumption by 0.41 servings/day compared with a decrease of −1.19 for those who rarely/never used Veggie Van (n = 27), a total difference of 1.6 servings/day (P = .01). There were no statistically significant differences in F&V consumption between groups based on the FFQ measure. Frequent shoppers reported additional health improvements and increases in their ability to buy enough F&V. We conclude that offering weekly boxes of affordable F&V paired with education in underserved communities may improve F&V consumption for frequent program users. PMID:28529669

Veggie Van Pilot Study: Impact of a Mobile Produce Market for Underserved Communities on Fruit and Vegetable Access and Intake.

PubMed

Leone, Lucia A; Haynes-Maslow, Lindsey; Ammerman, Alice S

2017-01-01

We conducted a pilot evaluation of the Veggie Van, a mobile produce market that brings weekly boxes of reduced-cost locally grown fruits and vegetables (F&V) to lower-income communities and offers cooking and nutrition education to customers. We conducted surveys just prior to starting Veggie Van at each of 3 sites and again at 2-3 months. F&V intake was measured with a 2-question item and a 10-item food frequency questionnaire (FFQ) in a subset of participants. At baseline, average servings/day of F&V was 4.9 (SD = 2.6, n = 60). At follow-up, individuals who reported shopping at Veggie Van frequently (n = 32) increased their F&V consumption by 0.41 servings/day compared with a decrease of -1.19 for those who rarely/never used Veggie Van (n = 27), a total difference of 1.6 servings/day (P = .01). There were no statistically significant differences in F&V consumption between groups based on the FFQ measure. Frequent shoppers reported additional health improvements and increases in their ability to buy enough F&V. We conclude that offering weekly boxes of affordable F&V paired with education in underserved communities may improve F&V consumption for frequent program users.

Assessing the role of syringe dispensing machines and mobile van outlets in reaching hard-to-reach and high-risk groups of injecting drug users (IDUs): a review

PubMed Central

Islam, Md Mofizul; Conigrave, Katherine M

2007-01-01

Reaching hard-to-reach and high-risk injecting drug users (IDUs) is one of the most important challenges for contemporary needle syringe programs (NSPs). The aim of this review is to examine, based upon the available international experience, the effectiveness of syringe vending machines and mobile van/bus based NSPs in making services more accessible to these hard-to-reach and high-risk groups of IDUs. A literature search revealed 40 papers/reports, of which 18 were on dispensing machines (including vending and exchange machines) and 22 on mobile vans. The findings demonstrate that syringe dispensing machines and mobile vans are promising modalities of NSPs, which can make services more accessible to the target group and in particular to the harder-to-reach and higher-risk groups of IDUs. Their anonymous and confidential approaches make services attractive, accessible and acceptable to these groups. These two outlets were found to be complementary to each other and to other modes of NSPs. Services through dispensing machines and mobile vans in strategically important sites are crucial elements in continuing efforts in reducing the spread of HIV and other blood borne viruses among IDUs. PMID:17958894

USAF Summer Faculty Research Program. 1981 Research Reports. Volume II.

DTIC Science & Technology

1981-10-01

Research Associate 17 (A) Spect roscop i( Analysis anld Opt. i n1iZaLtol on 1 Di. Larry R. Dalton the oxygen/ I od ine Chemica (tILase r and (8...theory appear in Fig. 7 where the inverse temper- ature dependence reflects the dominant influence of the van der Waals 2.7 attraction. Note that the...colinear geometry. Coltrin obtains a 13 depth of 6.9 kcal/mol vs. 2.7 kcal/mol obtained by Wilkins. Thus we expect more Coltrin trajectories to form van der

Rapid estimation of the electron correlation energy for van der Waals complexes RgX (Rg = Kr, Xe, X = Br, I)

NASA Astrophysics Data System (ADS)

Xinying, Li; Yongfang, Zhao; Xiaogong, Jing; Fengli, Liu; Fengyou, Hao

2006-01-01

We present the rules of electron correlation energies for RgX (Rg = Kr, Xe, X = Br, I) van der Waals (vdW) complex systems at CCSD(T) theoretical level with SDB-cc-pVQZ basis set by the Gaussian 98 program. A new method to derive the dispersion coefficient C6 by fitting the intermonomer electron correlation energies to C6R-6 function is introduced. The present C6 values are compared with the corresponding theoretical ones.

The Influence of Protection, Mobility and Risk Perception on the Behaviour and Physical Performance of a Combat Soldier (De Invloed van Bescherming, Mobiliteit en Risicoperceptie op het Gedrag en de Fysieke Prestatie van een Gevechtssoldaat)

DTIC Science & Technology

2006-12-01

2004). The trade off between protection and performance for dismounted infantry in the assault. Personal Armour System Symposium, PASS-2004, Kijkduin...of protection, mobility and risk Info-DenV@tno.nl perception on the behaviour and physical performance of a combat soldier Date December 2006 Author(s...behaviour and physical performance of a combat soldier Programmanummer Projectnummer V205 014.16190 Program maplanning Projectplannlng Start 01-04-2003

Overview: Western Regional applications Program (WRAP) status

NASA Technical Reports Server (NTRS)

Norman, S. M.

1981-01-01

Interactions with all 14 of the states in the Western Region over the past three years are reviewed from NASA's perspective. Outreach and training programs using the M mobile analysis and training extension van, the University Program, classes at the Ames Center, demonstration tests with state agencies, and surveying the needs of local governments are highlighted. Planned activities, the continuance of ASVT's, and the impact of the budget cuts on NASA'S technology program are also considered.

A facile and efficient dry transfer technique for two-dimensional Van derWaals heterostructure

NASA Astrophysics Data System (ADS)

Xie, Li; Du, Luojun; Lu, Xiaobo; Yang, Rong; Shi, Dongxia; Zhang, Guangyu

2017-08-01

Not Available Project supported by the National Basic Research Program of China (Grant Nos. 2013CB934500 and 2013CBA01602), the National Natural Science Foundation of China (Grant Nos. 61325021, 11574361, and 51572289), the Key Research Program of Frontier Sciences, CAS, (Grant No. QYZDB-SSW-SLH004), and the Strategic Priority Research Program (B), CAS (Grant No. XDB07010100).

Comparison of Integer Programming (IP) Solvers for Automated Test Assembly (ATA). Research Report. ETS RR-15-05

ERIC Educational Resources Information Center

Donoghue, John R.

2015-01-01

At the heart of van der Linden's approach to automated test assembly (ATA) is a linear programming/integer programming (LP/IP) problem. A variety of IP solvers are available, ranging in cost from free to hundreds of thousands of dollars. In this paper, I compare several approaches to solving the underlying IP problem. These approaches range from…

Current Programme 1991.

ERIC Educational Resources Information Center

Bernard Van Leer Foundation, The Hague (Netherlands).

The first section of this program report is a general description of the Bernard van Leer Foundation and its work. The second and third sections are the Foundation's annual report and financial report for 1990. The fourth and largest section of the program report consists of descriptions of 107 projects in 41 countries that are financed and…

From the IGY to the IHY: A Changing View of the Van Allen Radiation Belts

NASA Astrophysics Data System (ADS)

Hudson, M. K.

2006-12-01

Discovery of the Van Allen radiation belts by instrumentation flown on Explorer 1 in 1958 was the first major discovery of the Space Age. A view of the belts as static inner and outer zones of energetic particles with different sources, a double-doughnut encircling the Earth, became iconic to the point that their dynamic behavior and solar connection receded from public awareness and apparent scientific import. Then the Cycle 23 maximum in solar activity arrived in 1989-1991, the first approaching the activity level of the International Geophysical Year of 1957-58, when the Van Allen belts were first discovered. Delay in launch of the NASA-Air Force Combined Radiation Release and Effects Satellite, following the Challenger accident in 1986, led to having the right instruments in the right orbit at the right time to detect prompt injection of outer belt electrons and solar energetic protons into the `slot region' between the inner and outer belts, forming new trapped populations which lasted for years in an otherwise benign location. This event in March 1991, along with the great geomagnetic storm of March 1989, and our increased dependence on space technology since the early Explorer days, led to a resurgence of interest in the Van Allen radiation belts and understanding of their connectivity to the Sun. Additional instrumentation from NASA's International Solar Terrestrial Physics Program, the Solar Anomalous and Magnetospheric Particle Explorer (SAMPEX) and IMAGE spacecraft from the Explorer program, NOAA and DOD spacecraft, and improved worldwide linkages of groundbased measurements have contributed much since 1991 to our understanding of the dynamic characteristics of the Van Allen belts. Further, the presence of continuous solar wind measurements beginning with the launch of WIND in 1994, and SOHO images of Coronal Mass Ejections and coronal hole sources of high speed solar wind flow have filled in the connection with solar activity qualitatively anticipated with the choice of solar maximum for the IGY. Still, much remains to be done in terms of predictive capability. The need for such capability gave rise to establishing the National Space Weather Program a decade ago, while the fundamental science questions of solar-terrestrial connectivity remain drivers for NASA's Living With a Star program and other focused projects such as the NSF-sponsored Center for Integrated Space Weather Modeling. As measurements of emerging solar active regions have greatly improved, soon to be given a STERIO view, computer modeling capability has developed beyond the wildest expectations of Professor Van Allen and colleagues who launched the first Geiger counter into space on a satellite with no data storage device (once called a tape recorder). Results from recent simulations attempting both to describe particle acceleration processes quantitatively and predict impact on the near Earth space environment will be presented.

A statistical model to estimate refractivity turbulence structure constant C sub n sup 2 in the free atmosphere

NASA Technical Reports Server (NTRS)

Warnock, J. M.; Vanzandt, T. E.

1986-01-01

A computer program has been tested and documented (Warnock and VanZandt, 1985) that estimates mean values of the refractivity turbulence structure constant in the stable free atmosphere from standard National Weather Service balloon data or an equivalent data set. The program is based on the statistical model for the occurrence of turbulence developed by VanZandt et al. (1981). Height profiles of the estimated refractivity turbulence structure constant agree well with profiles measured by the Sunset radar with a height resolution of about 1 km. The program also estimates the energy dissipation rate (epsilon), but because of the lack of suitable observations of epsilon, the model for epsilon has not yet been evaluated sufficiently to be used in routine applications. Vertical profiles of the refractivity turbulence structure constant were compared with profiles measured by both radar and optical remote sensors and good agreement was found. However, at times the scintillometer measurements were less than both the radar and model values.

Contraception and clean needles: feasibility of combining mobile reproductive health and needle exchange services for female exotic dancers.

PubMed

Moore, Eva; Han, Jennifer; Serio-Chapman, Christine; Mobley, Cynthia; Watson, Catherine; Terplan, Mishka

2012-10-01

Young women engaged in exotic dancing have a higher need for reproductive health services than women not in this profession, and many also use drugs or exchange sex for money or drugs. Few report receiving reproductive health services. We describe a public health, academic, and community partnership that provided reproductive health services on needle exchange mobile vans in the "red light district" in downtown Baltimore, Maryland. Women made 220 visits to the vans in the first 21 months of the program's operation, and 65% of these visits involved provision of contraception. Programmatic costs were feasible. Joint provision of needle exchange and reproductive health services targeting exotic dancers has the potential to reduce unintended pregnancies and link pregnant, substance-abusing women to reproductive care, and such programs should be implemented more widely.

Promotores Comunitarios: sus aportes y difficultades (Community Facilitators: Their Contributions and Difficulties.) Occasional Paper No. 4.

ERIC Educational Resources Information Center

Brouwer, Jani; Martinic, Sergio

The Bernard van Leer Foundation sponsors nontraditional, nonschool programs designed to improve the chances that preschoolers will enroll in school. In these programs and other informal education efforts, the community facilitator plays an important role. Typically, the facilitator is a member of the community who works without remuneration as a…

Reemployment Assistance for Engineers, Scientists, and Technicians Unemployed Because of Aerospace and Defense Cutbacks. Report to Congress.

ERIC Educational Resources Information Center

Comptroller General of the U.S., Washington, DC.

As a report on the Department of Labor's Technology Mobilization and Reemployment (TMR) program, findings and conclusions from an evaluative review are presented in this volume. Information is obtained from state eployment security offices in Los Angeles and Van Nuys, California; Seattle; Denver; and New Orleans. The program accomplishments are…

A computer program for estimating the power-density spectrum of advanced continuous simulation language generated time histories

NASA Technical Reports Server (NTRS)

Dunn, H. J.

1981-01-01

A computer program for performing frequency analysis of time history data is presented. The program uses circular convolution and the fast Fourier transform to calculate power density spectrum (PDS) of time history data. The program interfaces with the advanced continuous simulation language (ACSL) so that a frequency analysis may be performed on ACSL generated simulation variables. An example of the calculation of the PDS of a Van de Pol oscillator is presented.

Light Duty Truck Weight Reduction Evaluation

DOT National Transportation Integrated Search

1980-10-01

The objectives of this program were to identify the weight reduction potential of pickup trucks, vans, and utility vehicles less than or equal to 8500 lb. gross vehicle weight through design modification, redesign, and material substitution; and more...

Phase 1 results from the Stirling-powered vehicle project

NASA Technical Reports Server (NTRS)

Shaltens, Richard K.

1988-01-01

The NASA Technology Utilization (TU) Office is sponsoring a multiyear, multiphase demonstration program to assess the technology developed under the DOE/NASA automotive Stirling engine (ASE) program with engines installed in various Air Force vehicles while being evaluated by independent third parties under realistic conditions. This paper reviews the operational history of Phase 1 with a Mod 1 Stirling engine installed in an Air Force multistop van in a variety of missions. Ten months of operation were with Air Force personnel at Langley Air Force Base, Virginia, where over 1100 hr and 4000 mi were logged on the Langley flight line. The Stirling-powered van operated on unleaded gasoline, JP-4 aircraft fuel, and diesel fuel at Langley Air Force Base. Two months of operation were completed with Deere and Company personnel in the Moline, Illinois area where over 175 hr and 2650 mi were logged on a Deere mail delivery route.

Spacecraft-level verification of the Van Allen Probes' RF communication system

NASA Astrophysics Data System (ADS)

Crowne, M. J.; Srinivasan, D.; Royster, D.; Weaver, G.; Matlin, D.; Mosavi, N.

This paper presents the verification process, lessons learned, and selected test results of the radio frequency (RF) communication system of the Van Allen Probes, formerly known as the Radiation Belt Storm Probes (RBSP). The Van Allen Probes mission is investigating the doughnut-shaped regions of space known as the Van Allen radiation belts where the Sun interacts with charged particles trapped in Earth's magnetic field. Understanding this dynamic area that surrounds our planet is important to improving our ability to design spacecraft and missions for reliability and astronaut safety. The Van Allen Probes mission features two nearly identical spacecraft designed, built, and operated by the Johns Hopkins University Applied Physics Laboratory (JHU/APL) for the National Aeronautics and Space Administration (NASA). The RF communication system features the JHU/APL Frontier Radio. The Frontier Radio is a software-defined radio (SDR) designed for spaceborne communications, navigation, radio science, and sensor applications. This mission marks the first spaceflight usage of the Frontier Radio. RF ground support equipment (RF GSE) was developed using a ground station receiver similar to what will be used in flight and whose capabilities provided clarity into RF system performance that was previously not obtained until compatibility testing with the ground segments. The Van Allen Probes underwent EMC, acoustic, vibration, and thermal vacuum testing at the environmental test facilities at APL. During this time the RF communication system was rigorously tested to ensure optimal performance, including system-level testing down to threshold power levels. Compatibility tests were performed with the JHU/APL Satellite Communication Facility (SCF), the Universal Space Network (USN), and the Tracking and Data Relay Satellite System (TDRSS). Successful completion of this program as described in this paper validated the design of the system and demonstrated that it will be able to me- t all of the Van Allen Probes's communications requirements with its intended ground segments.

Web-Based 3D Technology for Scenario Authoring and Visualization: The Savage Project

DTIC Science & Technology

2001-01-01

T. M., & Sadhu, P. (2001). XML How to Program . Upper Saddle River, New Jersey: Prentice Hall. Foley, J. D., van Dam, A., Feiner, S. K., & Hughes...Following graduation from NPS in September 2001, Major Nicklaus will be assigned to the Marine Air-Ground Task Force (MAGTF) Staff Training Program ...goal is to accelerate the worldwide demand for products based on these standards through the sponsorship of market and user education programs . The

Hilbert's sixth problem and the failure of the Boltzmann to Euler limit

NASA Astrophysics Data System (ADS)

Slemrod, Marshall

2018-04-01

This paper addresses the main issue of Hilbert's sixth problem, namely the rigorous passage of solutions to the mesoscopic Boltzmann equation to macroscopic solutions of the Euler equations of compressible gas dynamics. The results of the paper are that (i) in general Hilbert's program will fail because of the appearance of van der Waals-Korteweg capillarity terms in a macroscopic description of motion of a gas, and (ii) the van der Waals-Korteweg theory itself might satisfy Hilbert's quest for a map from the `atomistic view' to the laws of motion of continua. This article is part of the theme issue `Hilbert's sixth problem'.

They Won't Take No for an Answer: The Relais Enfants-Parents. Early Childhood Development: Practice and Reflections Number 11.

ERIC Educational Resources Information Center

Ayre, Elizabeth

The Bernard van Leer Foundation initiated a program in France entitled Relais Enfants-Parents to bring the children of prisoners to the forefront of social, political and judicial policy. The Relais Enfants-Parents program works to safeguard the psychological and emotional development of children by serving as a link between them and their…

Car Builder: Design, Construct and Test Your Own Cars. School Version with Lesson Plans. [CD-ROM].

ERIC Educational Resources Information Center

Highsmith, Joni Bitman

Car Builder is a scientific CD-ROM-based simulation program that lets students design, construct, modify, test, and compare their own cars. Students can design sedans, four-wheel-drive vehicles, vans, sport cars, and hot rods. They may select for aerodynamics, power, and racing ability, or economic and fuel efficiency. It is a program that teaches…

The Pacific northwest stream quality assessment

USGS Publications Warehouse

Van Metre, Peter C.; Morace, Jennifer L.; Sheibley, Rich W.

2015-01-01

The Pacific Northwest study will be the third regional study by the NAWQA program, and it will be of similar design and scope as the first two—the Midwest in 2013 and the Southeast in 2014 (Van Metre and others, 2012, 2014).

User-Side Subsidies for the Elderly and Handicapped in Lawrence, Massachusetts

DOT National Transportation Integrated Search

1984-06-01

Funding provided by the Service and Methods Demonstration (SMD) Program of the U.S. Department of Transportation, Urban Mass Transportation Administration, was used to subsidize the bus, taxicab, and wheelchair lift-equipped van travel of elderly and...

James A. Van Allen: The Trip to Jupiter

ERIC Educational Resources Information Center

Jacobsen, Sally

1973-01-01

Discusses the research purposes and activities of the Pioneer mission, including the instruments used, data on Jupiter's radiation belt, and information about cosmic ray intensity. Included is a description of the scientist's view about the value of the space program. (CC)

Using the Van Hiele theory to analyze primary school teachers' written work on geometrical proof problems

NASA Astrophysics Data System (ADS)

Jupri, A.

2018-05-01

The lack of ability of primary school teachers in deductive thinking, such as doing geometrical proof, is an indispensable issue to be dealt with. In this paper, we report on results of a three-step of the field document study. The study was part of a pilot study for improving deductive thinking ability of primary school teachers. First, we designed geometrical proof problems adapted from literature. Second, we administered an individual written test involving nine master students of primary education program, in which they are having experiences as primary school mathematics teachers. Finally, we analyzed the written work from the view of the Van Hiele theory. The results revealed that even if about the half of the teachers show ability in doing formal proof, still the rest provides inappropriate proving. For further investigation, we wonder whether primary school teachers would show better deductive thinking if the teaching of geometry is designed in a systematic and appropriate manner according to the Van Hiele theory.

Confirmational study: a positive-based thumb and finger sucking elimination program.

PubMed

Green, Shari E

2010-11-01

This article emphasizes the critical need for information specifically regarding the topic of retained sucking behaviors. The study aimed to confirm results provided by Van Norman of 723 subjects in 1997. Parent surveys were collected on 441 subjects who received an orofacial myofunctional treatment program provided by one certified orofacial myologist. Results of this study do confirm that retained digit sucking behavior may be addressed successfully and expediently by a program based on positive behavior modification techniques.

Operations manual for portable profiler : installing and using the portable profiler.

DOT National Transportation Integrated Search

2010-06-01

This manual is divided into two sections. The first is using the UTA-Profiler Program : with the portable profiler for generating surface profilers. The second is installing the : portable profiler module on a typical van or truck. The calibration an...

Instructional Aspects of Intelligent Tutoring Systems.

ERIC Educational Resources Information Center

Pieters, Jules M., Ed.

This collection contains three papers addressing the instructional aspects of intelligent tutoring systems (ITS): (1) "Some Experiences with Two Intelligent Tutoring Systems for Teaching Computer Programming: Proust and the LISP-Tutor" (van den Berg, Merrienboer, and Maaswinkel); (2) "Some Issues on the Construction of Cooperative…

Effectiveness and efficiency of safety belt and child restraint usage programs

DOT National Transportation Integrated Search

1982-03-01

Problem: Each year, approximately 34,000 persons are killed and 520,000 receive moderate to severe injuries as occupants of passenger cars, light trucks and vans. Approximately half ofthese deaths and injuries could be avoided if all such occupants w...

42 CFR 411.351 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM EXCLUSIONS FROM MEDICARE AND LIMITATIONS ON MEDICARE PAYMENT Financial Relationships Between Physicians and... and that is used exclusively by the group practice. Space in a building or a mobile vehicle, van, or...

Foundation Level Training. Trainer's Manual.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Human Services, Oklahoma City. Developmental Disabilities Services Div.

This trainer's manual was developed to provide a consistent knowledge and skill base (i.e., a "foundation") for all individuals employed in programs funded by Oklahoma's Developmental Disabilities Services Division. They include van drivers, recreation workers, residential staff, administrators, case managers, secretarial/clerical staff,…

Tidal analysis and Arrival Process Mining Using Automatic Identification System (AIS) Data

DTIC Science & Technology

2017-01-01

files, organized by location. The data were processed using the Python programming language (van Rossum and Drake 2001), the Pandas data analysis...ER D C/ CH L TR -1 7- 2 Coastal Inlets Research Program Tidal Analysis and Arrival Process Mining Using Automatic Identification System...17-2 January 2017 Tidal Analysis and Arrival Process Mining Using Automatic Identification System (AIS) Data Brandan M. Scully Coastal and

A Study of Army Civilian Entry Level and Mid-Level Program Management Leadership Development

DTIC Science & Technology

2016-05-08

and mid-grade level positions is an important responsibility for senior leaders. Mentoring and coaching entry level and mid-grade level...Program Management Leadership Development Craig J. Maurice Defense Acquisition University Senior Service College Fellowship 2015-2016 Huntsville...requirements for the Army’s Senior Service College Fellowship (SSCF) under the direction of SSCF Director, Mr. John Daniels and Research Advisor, Mr. Van

Sulfate reduction controlled by organic matter availability in deep sediment cores from the saline, alkaline Lake Van (Eastern Anatolia, Turkey)

PubMed Central

Glombitza, Clemens; Stockhecke, Mona; Schubert, Carsten J.; Vetter, Alexandra; Kallmeyer, Jens

2013-01-01

As part of the International Continental Drilling Program deep lake drilling project PaleoVan, we investigated sulfate reduction (SR) in deep sediment cores of the saline, alkaline (salinity 21.4‰, alkalinity 155 m mEq-1, pH 9.81) Lake Van, Turkey. The cores were retrieved in the Northern Basin (NB) and at Ahlat Ridge (AR) and reached a maximum depth of 220 m. Additionally, 65–75 cm long gravity cores were taken at both sites. SR rates (SRR) were low (≤22 nmol cm-3 day-1) compared to lakes with higher salinity and alkalinity, indicating that salinity and alkalinity are not limiting SR in Lake Van. Both sites differ significantly in rates and depth distribution of SR. In NB, SRR are up to 10 times higher than at AR. SR could be detected down to 19 mblf (meters below lake floor) at NB and down to 13 mblf at AR. Although SRR were lower at AR than at NB, organic matter (OM) concentrations were higher. In contrast, dissolved OM in the pore water at AR contained more macromolecular OM and less low molecular weight OM. We thus suggest, that OM content alone cannot be used to infer microbial activity at Lake Van but that quality of OM has an important impact as well. These differences suggest that biogeochemical processes in lacustrine sediments are reacting very sensitively to small variations in geological, physical, or chemical parameters over relatively short distances. PMID:23908647

vanC Cluster of Vancomycin-Resistant Enterococcus gallinarum BM4174

PubMed Central

Arias, Cesar A.; Courvalin, Patrice; Reynolds, Peter E.

2000-01-01

Glycopeptide-resistant enterococci of the VanC type synthesize UDP-muramyl-pentapeptide[d-Ser] for cell wall assembly and prevent synthesis of peptidoglycan precursors ending in d-Ala. The vanC cluster of Enterococcus gallinarum BM4174 consists of five genes: vanC-1, vanXYC, vanT, vanRC, and vanSC. Three genes are sufficient for resistance: vanC-1 encodes a ligase that synthesizes the dipeptide d-Ala-d-Ser for addition to UDP-MurNAc-tripeptide, vanXYC encodes a d,d-dipeptidase–carboxypeptidase that hydrolyzes d-Ala-d-Ala and removes d-Ala from UDP-MurNAc-pentapeptide[d-Ala], and vanT encodes a membrane-bound serine racemase that provides d-Ser for the synthetic pathway. The three genes are clustered: the start codons of vanXYC and vanT overlap the termination codons of vanC-1 and vanXYC, respectively. Two genes which encode proteins with homology to the VanS-VanR two-component regulatory system were present downstream from the resistance genes. The predicted amino acid sequence of VanRC exhibited 50% identity to VanR and 33% identity to VanRB. VanSC had 40% identity to VanS over a region of 308 amino acids and 24% identity to VanSB over a region of 285 amino acids. All residues with important functions in response regulators and histidine kinases were conserved in VanRC and VanSC, respectively. Induction experiments based on the determination of d,d-carboxypeptidase activity in cytoplasmic extracts confirmed that the genes were expressed constitutively. Using a promoter-probing vector, regions upstream from the resistance and regulatory genes were identified that have promoter activity. PMID:10817725

Multimedia.

ERIC Educational Resources Information Center

Northwest Regional Educational Lab., Portland, OR.

The second session of IT@EDU98 consisted of four papers on multimedia and was chaired by Luu Tien Hiep (Lotus College, Vietnam). "Multimedia Education" (Tran Van Hao, Ngo Huy Hoang) describes "Multimedia Education v. 1.0," an educational software program for elementary school children that uses games to teach counting,…

Learning Objects: A User-Centered Design Process

ERIC Educational Resources Information Center

Branon, Rovy F., III

2011-01-01

Design research systematically creates or improves processes, products, and programs through an iterative progression connecting practice and theory (Reinking, 2008; van den Akker, 2006). Developing a new instructional systems design (ISD) processes through design research is necessary when new technologies emerge that challenge existing practices…

[AERA. Dream machines and computing practices at the Mathematical Center].

PubMed

Alberts, Gerard; De Beer, Huub T

2008-01-01

Dream machines may be just as effective as the ones materialised. Their symbolic thrust can be quite powerful. The Amsterdam 'Mathematisch Centrum' (Mathematical Center), founded February 11, 1946, created a Computing Department in an effort to realise its goal of serving society. When Aad van Wijngaarden was appointed as head of the Computing Department, however, he claimed space for scientific research and computer construction, next to computing as a service. Still, the computing service following the five stage style of Hartree's numerical analysis remained a dominant characteristic of the work of the Computing Department. The high level of ambition held by Aad van Wijngaarden lead to ever renewed projections of big automatic computers, symbolised by the never-built AERA. Even a machine that was actually constructed, the ARRA which followed A.D. Booth's design of the ARC, never made it into real operation. It did serve Van Wijngaarden to bluff his way into the computer age by midsummer 1952. Not until January 1954 did the computing department have a working stored program computer, which for reasons of policy went under the same name: ARRA. After just one other machine, the ARMAC, had been produced, a separate company, Electrologica, was set up for the manufacture of computers, which produced the rather successful X1 computer. The combination of ambition and absence of a working machine lead to a high level of work on programming, way beyond the usual ideas of libraries of subroutines. Edsger W. Dijkstra in particular led the way to an emphasis on the duties of the programmer within the pattern of numerical analysis. Programs generating programs, known elsewhere as autocoding systems, were at the 'Mathematisch Centrum' called 'superprograms'. Practical examples were usually called a 'complex', in Dutch, where in English one might say 'system'. Historically, this is where software begins. Dekker's matrix complex, Dijkstra's interrupt system, Dijkstra and Zonneveld's ALGOL compiler--which for housekeeping contained 'the complex'--were actual examples of such super programs. In 1960 this compiler gave the Mathematical Center a leading edge in the early development of software.

Genetics Home Reference: achromatopsia

MedlinePlus

... NW, Roosing S, van Schooneveld MJ, van Lith-Verhoeven JJ, van Moll-Ramirez N, van den Born LI, ... van Schooneveld MJ, Strom TM, van Lith-Verhoeven JJ, Lotery AJ, van Moll-Ramirez N, Leroy BP, ...

Glycopeptide Resistance vanA Operons in Paenibacillus Strains Isolated from Soil

PubMed Central

Guardabassi, Luca; Perichon, Bruno; van Heijenoort, Jean; Blanot, Didier; Courvalin, Patrice

2005-01-01

The sequence and gene organization of the van operons in vancomycin (MIC of >256 μg/ml)- and teicoplanin (MIC of ≥32 μg/ml)-resistant Paenibacillus thiaminolyticus PT-2B1 and Paenibacillus apiarius PA-B2B isolated from soil were determined. Both operons had regulatory (vanR and vanS), resistance (vanH, vanA, and vanX), and accessory (vanY, vanZ, and vanW) genes homologous to the corresponding genes in enterococcal vanA and vanB operons. The vanAPT operon in P. thiaminolyticus PT-2B1 had the same gene organization as that of vanA operons whereas vanAPA in P. apiarius PA-B2B resembled vanB operons due to the presence of vanW upstream from the vanHAX cluster but was closer to vanA operons in sequence. Reference P. apiarius strains NRRL B-4299 and NRRL B-4188 were found to harbor operons indistinguishable from vanAPA by PCR mapping, restriction fragment length polymorphism, and partial sequencing, suggesting that this operon was species specific. As in enterococci, resistance was inducible by glycopeptides and associated with the synthesis of pentadepsipeptide peptidoglycan precursors ending in d-Ala-d-Lac, as demonstrated by d,d-dipeptidase activities, high-pressure liquid chromatography, and mass spectrometry. The precursors differed from those in enterococci by the presence of diaminopimelic acid instead of lysine in the peptide chain. Altogether, the results are compatible with the notion that van operons in soil Paenibacillus strains and in enterococci have evolved from a common ancestor. PMID:16189102

Glycopeptide resistance vanA operons in Paenibacillus strains isolated from soil.

PubMed

Guardabassi, Luca; Perichon, Bruno; van Heijenoort, Jean; Blanot, Didier; Courvalin, Patrice

2005-10-01

The sequence and gene organization of the van operons in vancomycin (MIC of >256 microg/ml)- and teicoplanin (MIC of > or =32 microg/ml)-resistant Paenibacillus thiaminolyticus PT-2B1 and Paenibacillus apiarius PA-B2B isolated from soil were determined. Both operons had regulatory (vanR and vanS), resistance (vanH, vanA, and vanX), and accessory (vanY, vanZ, and vanW) genes homologous to the corresponding genes in enterococcal vanA and vanB operons. The vanA(PT) operon in P. thiaminolyticus PT-2B1 had the same gene organization as that of vanA operons whereas vanA(PA) in P. apiarius PA-B2B resembled vanB operons due to the presence of vanW upstream from the vanHAX cluster but was closer to vanA operons in sequence. Reference P. apiarius strains NRRL B-4299 and NRRL B-4188 were found to harbor operons indistinguishable from vanA(PA) by PCR mapping, restriction fragment length polymorphism, and partial sequencing, suggesting that this operon was species specific. As in enterococci, resistance was inducible by glycopeptides and associated with the synthesis of pentadepsipeptide peptidoglycan precursors ending in D-Ala-D-Lac, as demonstrated by D,D-dipeptidase activities, high-pressure liquid chromatography, and mass spectrometry. The precursors differed from those in enterococci by the presence of diaminopimelic acid instead of lysine in the peptide chain. Altogether, the results are compatible with the notion that van operons in soil Paenibacillus strains and in enterococci have evolved from a common ancestor.

A Research Program in Computer Technology

DTIC Science & Technology

1975-09-01

Dale M. Chase Neil M. Goldman Jeannette Christen~sen Norton R. Green feld Kathie Cole grove John F. Heafner Nancy Dechter James Koda Oralio E. Garza...Thomas L. Boynton Stephen L. Casner E. Randolph Cole James Koda Robert Parker Paul Raveling Dono Van-Mierop Research Assistant: John K. Kastner

Impact of Formal Mentoring on Freshmen Expectations, Graduation Rates, and GPAs

ERIC Educational Resources Information Center

Clark, Nancy C.; Heilmann, Sharon G.; Johnson, Adrianne; Taylor, Ryan

2016-01-01

This quantitative study examines the expectations, graduation rates, and GPAs of participants (n = 113) in a formal mentorship program, "Freshmen Focus," at a small, rural Midwestern high school through the framework of organizational socialization theory (Van Maanen & Schein, 1977). Findings indicate freshmen students formed…

The Professional Development of Graduate Teaching Assistants.

ERIC Educational Resources Information Center

Marincovich, Michele, Ed.; Prostko, Jack, Ed.; Stout, Frederic, Ed.

Sixteen papers address the training and professional development of graduate teaching assistants. The papers are: (1) "Preparing Graduate Students To Teach: Past, Present, and Future" (Nancy Van Note Chism); (2) "The Role of Centralized Programs in Preparing Graduate Students To Teach" (Jacqueline A. Mintz); (3) "The Disciplinary/Departmental…

Saved by the BEL.

ERIC Educational Resources Information Center

Eppolito, Antonio; And Others

1995-01-01

BEL, a partnership involving Blue Cross/Blue Shield of Central New York, a Syracuse elementary school, and Le Moyne College, provides an effective, low-cost, individually tailored supplemental reading program allowing poor readers to catch up with their classmates. Le Moyne supplies undergraduate tutors and a van; the insurance company provides…

Developing Intercultural Competence by Participating in Intensive Intercultural Service-Learning

ERIC Educational Resources Information Center

De Leon, Nadia

2014-01-01

This quasi-experimental study investigates the effects of an intensive intercultural service-learning program on the intercultural competence of undergraduate students by utilizing pre- and post-course assessments of intercultural competence as measured by the cultural intelligence (Van Dyne, Koh, & Ang, 2008) and intercultural sensitivity…

A Flash X-Ray Facility for the Naval Postgraduate School

DTIC Science & Technology

1985-06-01

ionizing radiation, *• NPS has had active programs with a Van de Graaff generator, a reactor, radioactive sources, X-ray machines and a linear electron ...interaction of radiation with matter and with coherent radiation. Currently the most active program is at the linear electron accelerator which over...twenty years has produced some 75 theses. The flash X-ray machine was obtained to expan-i and complement the capabilities of the linear electron

Obituary: Thomas C. Van Flandern (1940-2009)

NASA Astrophysics Data System (ADS)

Dunham, David; Slabinski, Victor

2011-12-01

Dr. Thomas Charles Van Flandern, an expert in celestial mechanics and cosmology, died January 9, 2009 in Seattle, Washington, of colon cancer. He was 68. Van Flandern was an astronomer at the U.S. Naval Observatory from 1963 to 1983. He developed software to predict and analyze lunar occultations to improve lunar orbital and fundamental star catalog data. In later years he championed increasingly controversial theories. But his 1978 prediction that some asteroids have natural satellites, which was almost universally rejected, was verified when the Galileo spacecraft photographed Dactyl, a satellite of (243) Ida, during its flyby in 1993. Besides astronomy and computers, he had strong interests in biochemistry and nutrition, and he ran a business selling personal computers in the 1980s. Tom Van Flandern was born June 26, 1940 in Cleveland, Ohio, the first child of Robert F. Van Flandern and Anna Mary Haley. His father, a police officer, left the family when Tom Van Flandern was 5. His mother died when he was 16; he and his siblings then lived with their grandmother, Margery Jobe, until he went to college. Tom Van Flandern became interested in astronomy as a child. He used his first telescope, purchased with newspaper delivery earnings, to observe lunar occultations, and then learned how to predict them, sparking a life-long passion for dynamical astronomy. While attending St. Ignatius High School, Van Flandern and fellow student Thomas Petrie organized the Cleveland Moonwatch team to observe the first artificial satellites, the only team without an adult organizer. In 1958, Tom Van Flandern entered Xavier University where he led the Cincinnati Moonwatch team. He learned computer programming at a summer job with General Electric and wrote software to calculate "look angles" from orbital elements. The Cincinnati team became a top producer of observations using these predictions. Tom obtained a B.S. in mathematics from Xavier in 1962. He spent the next year at Georgetown University studying astronomy. On July 6, 1963, Tom Van Flandern married Barbara Ann Weber in Kentucky. They remained together until his passing 46 years later. They had four children, Michael, Constance, Brian, and Kevin. Also in 1963, Tom began work in the Nautical Almanac Office of the U.S. Naval Observatory in Washington, DC. He became an expert on refining the lunar orbit from timings of lunar occultations, then the best observations for that purpose. He encouraged observations by providing observers with predictions of occultations for their locations. He designed a cable system connecting all observers timing a grazing occultation, to record their observations at a central station. After a 1964 success, four amateur astronomical societies built similar cable systems. Tom Van Flandern relished efforts to simplify computer calculations. He and Henry Fliegel developed an algorithm to calculate a Julian date from a Gregorian date that would fit on a single IBM card. They published this in a paper, "A machine algorithm for processing calendar dates" in 1968 in the Communications of the Association for Computing Machinery. This was used in countless business applications worldwide. With Kenneth Pulkkinen, he published "Low precision formulae for planetary positions", in Ap. J. Supp. in 1979. The paper set a record for the number of reprints requested from that journal. Tom Van Flandern earned a PhD in astronomy from Yale University in 1969. His thesis was "A discussion of 1950-1968 occultations of stars by the Moon," advised by Prof. G. M. Clemence. In 1976 Van Flandern asserted that the orbits of 60 long-period comets traced to a common origin, supporting Michael Ovenden's exploded planet hypothesis. He founded the non-profit Meta Research, Inc. in 1990 to provide support for alternative theories in astronomy. The Meta Research Bulletin reported the newest discoveries and how they presented difficulties to accepted astronomical theories, such as the Big Bang and planetary formation. The Bulletin claimed mainstream scientists preferred making ad hoc corrections to the theories rather than acknowledge fundamental difficulties that might jeopardize their funding. Tom Van Flandern's advocacy of an artificial origin for the "face on Mars," especially after higher-resolution images were taken in 2001, antagonized many. His questioning of the speed of gravity, first published in a 1998 paper in Physics Letters A, provoked additional attacks from relativists. He showed the same persistence with these controversies that had enabled him to solve complex programming and celestial mechanics problems. Tom Van Flandern did not reject General Relativity as some have asserted, but rather rejected its geometrical interpretation. He said: "General relativity has a geometric and a field interpretation. If angular momentum conservation is invoked in the geometric interpretation to explain experiments, the causality principle is violated. The field interpretation avoids this problem by allowing faster-than-light propagation in forward time." For more, see http://www.metaresearch.org/cosmology/gravity/speed_limit.asp. Tom Van Flandern strongly attacked some alternative theories, such as Velikovsky's ideas of recent planetary close approaches, turning one of Velikovsky's supporters, C. L. Ellenberger, into a strong critic. If not for these antagonisms, the "mainstream" part of Tom Van Flandern's work in later years might be better acknowledged, including his "Eclipse Edge" company that organized expeditions to several solar eclipses, and his work with E. Lyytinen on the passage of Earth through cometary debris trails. Their prediction was closest to the observed time of the Leonid storm maximum of November 2001. Tom Van Flandern held memberships in the International Astronomical Union, the American Astronomical Society (and in its Divisions on Dynamical Astronomy and Planetary Sciences), and several other scientific organizations. He received second prize from the Gravity Research Foundation in 1974 and the Astronomy Award from the Washington Academy of Sciences in 2000. An asteroid, (52266) 1986 AD, was named "Van Flandern" in his memory on February 9, 2009. Tom Van Flandern's survivors include his wife, Barbara; his brother William; and his four children. He was buried in Sequim, Washington, near his last home. His inquisitive mind, unshakable integrity, and boundless enthusiasm are remembered fondly by his friends and colleagues. He left behind a valuable legacy of astronomical work. More is at http://www.metaresearch.org/home/about meta research/resume.asp and in his 1999 book, "Dark Matter, Missing Planets and New Comets."

75 FR 74151 - Greenhouse Gas Emissions Standards and Fuel Efficiency Standards for Medium- and Heavy-Duty...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-30

...EPA and NHTSA, on behalf of the Department of Transportation, are each proposing rules to establish a comprehensive Heavy-Duty National Program that will reduce greenhouse gas emissions and increase fuel efficiency for on-road heavy-duty vehicles, responding to the President's directive on May 21, 2010, to take coordinated steps to produce a new generation of clean vehicles. NHTSA's proposed fuel consumption standards and EPA's proposed carbon dioxide (CO2) emissions standards would be tailored to each of three regulatory categories of heavy-duty vehicles: Combination Tractors; Heavy-Duty Pickup Trucks and Vans; and Vocational Vehicles, as well as gasoline and diesel heavy-duty engines. EPA's proposed hydrofluorocarbon emissions standards would apply to air conditioning systems in tractors, pickup trucks, and vans, and EPA's proposed nitrous oxide (N2O) and methane (CH4) emissions standards would apply to all heavy-duty engines, pickup trucks, and vans. EPA is also requesting comment on possible alternative CO2-equivalent approaches for model year 2012-14 light-duty vehicles. EPA's proposed greenhouse gas emission standards under the Clean Air Act would begin with model year 2014. NHTSA's proposed fuel consumption standards under the Energy Independence and Security Act of 2007 would be voluntary in model years 2014 and 2015, becoming mandatory with model year 2016 for most regulatory categories. Commercial trailers would not be regulated in this phase of the Heavy- Duty National Program, although there is a discussion of the possibility of future action for trailers.

Explorers Program Management

NASA Technical Reports Server (NTRS)

Volpe, Frank; Comberiate, Anthony B. (Technical Monitor)

2001-01-01

The mission of the Explorer Program is to provide frequent flight opportunities for world-class scientific investigations from space within the following space science themes: 1) Astronomical Search for Origins and Planetary Systems; 2) Structure and Evolution of the Universe; and 3) The Sun-Earth Connection. America's space exploration started with Explorer 1 which was launched February 1, 1958 and discovered the Van Allen Radiation Belts. Over 75 Explorer missions have flown. The program seeks to enhance public awareness of, and appreciation for, space science and to incorporate. educational and public outreach activities as integral parts of space science investigations.

Diversity of Tn1546 in vanA-positive Enterococcus faecium clinical isolates with VanA, VanB, and VanD phenotypes and susceptibility to vancomycin.

PubMed

Cha, J O; Yoo, J I; Kim, H K; Kim, H S; Yoo, J S; Lee, Y S; Jung, Y H

2013-10-01

To investigate diversity in the vanA cluster in Enterococcus faecium isolates from nontertiary hospitals. We identified 43 vanA-positive Ent. faecium isolates, including two vancomycin-susceptible isolates, from hospitals between 2003 and 2006. Of these isolates, >85% were resistant to ampicillin, erythromycin and ciprofloxacin. The vanA cluster was classified into six types using overlapping PCR, but the prototype transposon Tn1546 was not found. Most vanA-positive vancomycin-resistant Enterococcus (VRE) carried IS1216V and belonged to Type III (58·1%) or Type II (20·9%). vanY, vanZ and IS1216V were observed in the left and right ends of Type III with long-range PCR. IS1216V was also observed within vanS and vanX in the two vancomycin-susceptible isolates and in two vancomycin-resistant isolates. No VRE isolates with VanB and VanD phenotypes contained point mutations in vanS, unlike in previous reports. Sequence types (STs) of all isolates belonged to clonal complex 17, and ST78 was predominant. Insertion sequences, especially IS1216V, cause structural variation in the vanA cluster. We report the first observation of vanY and vanZ at the left end of Tn1546 in clinical isolates. This is the first report of the frequency of vancomycin resistance and diversity of Tn1546 in vanA-positive Ent. faecium isolates from nontertiary hospitals. © 2013 The Society for Applied Microbiology.

OMEGACAM and Gravitational Lensing

NASA Astrophysics Data System (ADS)

Christen, Fabrice Frédéric Thiébaut

2007-04-01

Het proefschrift van Fabrice Christen gaat over de ontwikkeling van nieuwe methoden voor het corrigeren van (digitale) foto's van melkwegstelsels. Met deze methoden kunnen de beelden uit het heelal beter worden geanalyseerd. Het eerste gedeelte is gewijd aan het werk dat bij ESO is uitgevoerd aan de CCD's van de OmegaCAM camera, het enige instrument van de VST. OmegaCAM is een optische groothoekcamera met een beeldveld van een vierkante graad, opgebouwd uit een mozaiek van 8 bij 4 CCD's. Van elk onderdeel moeten alle kenmerken volledig bekend zijn voordat het in het CCD mozaiek geplaatst kan worden. In het tweede deel van dit proefschrift wordt de ontwikkeling van een nieuwe methode voor het corrigeren van de ``point-spread function'' (PSF) en schatten van de ellipticiteit van de melkwegstelsels besproken. De nieuwe techniek wordt getest en vergeleken met een door sterrenkundigen algemeen gebruikte methode in het veld van zwaartekrachtslenzen, de Kaiser, Squire en Broadhurst (KSB) methode. De nieuwe methode, gebaseerd op shapelet ontleding (vergelijkbaar met wavelet ontleding), gaat verder, en is sneller en theoretisch preciezer dan de KSB methode. Door gebruik te maken van de gecorrigeerde ellipticiteit, kunnen we een statistische analyse uitvoeren om er een kosmisch vervormingssignaal uit te halen. De licht vervormde beelden van de melkwegstelsels bewij zen dat de niet-homogene massaverdeling op megaparsec-schaal voornamelijk bestaat uit grote hoeveelheden donkere materie. Verder vergelijken we de schattingen van de ellipticiteit van de shapelet en KSB methode. Bovendien voeren we ook nog een melkwegstelsel-melkwegstelsel lens analyse uit op de 50 VLT Fors1 afbeeldingen en slagen we erin de belangrijkste eigenschappen van de halo's van de stelsels, die zich op een afstand van een- tot tweeduizend megaparsec (1 parsec = 3,26 lichtjaar = 3,085 x 10^16 meter) bevinden, te bepalen door gebruik te maken van twee modellen van melkwegstelselhalo's. Vergeleken met andere overzichtsmetingen vinden we vergelijkbare resultaten.

Beam-dynamic effects at the CMS BRIL van der Meer scans

NASA Astrophysics Data System (ADS)

Babaev, A.

2018-03-01

The CMS Beam Radiation Instrumentation and Luminosity Project (BRIL) is responsible for the simulation and measurement of luminosity, beam conditions and radiation fields in the CMS experiment. The project is engaged in operating and developing new detectors (luminometers), adequate for the experimental conditions associated with high values of instantaneous luminosity delivered by the CERN LHC . BRIL operates several detectors based on different physical principles and technologies. Precise and accurate measurements of the delivered luminosity is of paramount importance for the CMS physics program. The absolute calibration of luminosity is achieved by the van der Meer method, which is carried out under specially tailored conditions. This paper presents models used to simulate of beam-dynamic effects arising due to the electromagnetic interaction of colliding bunches. These effects include beam-beam deflection and dynamic-β effect. Both effects are important to luminosity measurements and influence calibration constants at the level of 1-2%. The simulations are carried out based on 2016 CMS van der Meer scan data for proton-proton collisions at a center-of-mass energy of 13 TeV.

[Managing concerns about falls in older people: evaluation of the implementation of an evidence-based program].

PubMed

Zijlstra, G A R; Du Moulin, M F M T; van Haastregt, J C M; de Jonge, M; Kempen, G I J M; van der Poel, A

2013-12-01

A cognitive behavioral program reduced concerns about falling and related avoidance behavior among older community-dwelling adults in a randomized controlled trial. In the current study we examined the effects and acceptability of the program after nation-wide implementation into home care organizations in The Netherlands. In a one-group pretest-posttest study with data collection before the start of the program and at 2 and 4 months, the effects and acceptability of the program were assessed in 125 community-dwelling older people. The outcomes of the effect evaluation included concerns about falls, related avoidance behavior, falls, fall-related medical attention, feelings of anxiety, symptoms of depression, and loneliness. Pretest-posttest analyses with the Wilcoxon signed-rank test and the paired t-test showed significant improvements at 4 months for concerns about falls, activity avoidance, number of falls in the past 2 months, feelings of anxiety, and symptoms of depression. No significant differences were shown for the other outcomes. After implementation in home care organizations, the outcomes indicate positive program effects on concerns about falls, avoidance behavior, and falls in community-dwelling older people. Given the similarity in results, i.e. between those of the previously performed randomized controlled trial and those of the current pretest-posttest study, we conclude that the program can be successfully implemented in practice. This article is an adjusted, Dutch version of Zijlstra GA, van Haastregt JC, Du Moulin MF, de Jonge MC, van der Poel A, Kempen GI. Effects of the implementation of an evidenc-based program to manage concerns about falls in older adults. The Gerontologist 2013;53(5):839-849; doi: 10.1093/geront/gns142.

A Necessary Evil: The Experiences of Managers Implementing Downsizing Programmes

ERIC Educational Resources Information Center

Noronha, Ernesto; D'Cruz, Premilla

2006-01-01

This paper presents the findings of a phenomenological study, which describes the experiences of human resource (HR) managers implementing a downsizing program in a steel manufacturing organization in India. Data were collected through conversational interviews. Following van Manens sententious analytic approach, the core theme of a necessary…

A Multi-Level Approach to Caregiver Training Accessibility.

ERIC Educational Resources Information Center

Range, Diana

This brief paper discusses how in 10 year's time a system for providing caregiver training was developed in Texas. The training accessibility system consists of five dimensions: publications, free materials, resource rooms, child development specialists, Title XX training contracts and traveling resource vans. Tips for program continuity under…

Improving Target Detection in Visual Search Through the Augmenting Multi-Sensory Cues

DTIC Science & Technology

2013-01-01

target detection, visual search James Merlo, Joseph E. Mercado , Jan B.F. Van Erp, Peter A. Hancock University of Central Florida 12201 Research Parkway...were controlled by a purpose-created, LabView- based software computer program that synchronised the respective displays and recorded response times and

41 CFR 101-26.501-2 - Standardized buying programs.

Code of Federal Regulations, 2011 CFR

2011-07-01

... and 6×4 cab-chassis, stake, van, dump, and truck-tractor; 19,000 to 60,000 pounds GVWR. (ii) 4×4 and 6×4 cab-chassis, stake, dump, and truck-tractor; 26,000 to 52,000 pounds GVWR. (iii) 1,200 and 2,000...

Place-Based Education: A Transformative Activist Stance

ERIC Educational Resources Information Center

Coughlin, Christine A.; Kirch, Susan A.

2010-01-01

The ethnography presented by van Eijck and Roth focuses on the activities of people involved in a government funded internship program in conservation and restoration, which was offered by a "multidisciplinary research center" through a local First Nation adult education center. The internship was designed, in partnership with a local non-profit…

Adult Literacy and Numeracy: Assessing Change. Adult Literacy Research Network.

ERIC Educational Resources Information Center

Cumming, J. Joy, Ed.; van Kraayenoord, Christina E., Ed.

This document contains eight papers from an action research program to foster good practice in adult literacy provision and policy. "Introduction" (J. Joy Cumming, Christina E. van Kraayenoord) presents an overview of the action research project and individual reports. "Assessment: Making a Difference in Adult Literacy and Numeracy…

Technical Risk Identification at Program Inception Product Overview

DTIC Science & Technology

2014-05-08

hans.koenigsmann@spacex.com SpaceX James Koory james.koory@rocket.com Rocket Brian Kosinski Kosinski.Brian@ssd.loral.com SSL John Kowalchik john.j.kowalchik...Marvin VanderWeg marvin.vanderwag@spacex.com SpaceX Gerrit VanOmmering gerrit.vanommering@sslmda.com SSL Michael Verzuh mverzuh@ball.com Ball John Vilja

Technical Risk Identification at Program Inception

DTIC Science & Technology

2014-04-20

boeing.com Byron Knight NRO knightby@nro.mil Hans Koenigsmann SpaceX hans.koenigsmann@spacex.c om James Koory Rocket james.koory@rocket.com Brian Kosinski...Deborah Valley MIT deborah.valley@ll.mit.edu Fred Van Milligen JDSU fvanmilligen@jdsu.com Marvin VanderWeg SpaceX marvin.vanderwag@spacex.c om Gerrit

A distinctive dual-channel quorum-sensing system operates in Vibrio anguillarum.

PubMed

Croxatto, Antony; Pride, John; Hardman, Andrea; Williams, Paul; Cámara, Miguel; Milton, Debra L

2004-06-01

Many bacterial cells communicate using diffusible signal molecules to monitor cell population density via a process termed quorum sensing. In marine Vibrio species, the Vibrio harveyi-type LuxR protein is a key player in a quorum-sensing phosphorelay cascade, which controls the expression of virulence, symbiotic and survival genes. Previously, we characterized Vibrio anguillarum homologues of LuxR (VanT) and LuxMN (VanMN) and, in this study, we have identified homologues of LuxPQ (VanPQ) and LuxOU (VanOU). In contrast to other Vibrio species, vanT was expressed at low cell density and showed no significant induction as the cell number increased. In addition, although the loss of VanO increased vanT expression, the loss of VanU, unexpectedly, decreased it. Both VanN and VanQ were required for repression of vanT even in a vanU mutant, suggesting an alternative route for VanNQ signal transduction other than via VanU. VanT negatively regulated its own expression by binding and repressing the vanT promoter and by binding and activating the vanOU promoter. The signal relay results in a cellular response as expression of the metalloprotease, empA, was altered similar to that of vanT in all the mutants. Consequently, the V. anguillarum quorum-sensing phosphorelay systems work differently from those of V. harveyi and may be used to limit rather than induce vanT expression.

Dutch Anthropometry for Vehicle Design and Evaluation

DTIC Science & Technology

2008-10-01

middelen Beschrijving van de werkzaamheden Uitgaande van afmetingen van Nederlanders zijn grenswaarden voor negen paspoppen. met vanSrende...vastgesteld voor het jaar 2015 Hierbij is uitgegaan van een Nederlands antropometrisch bestand (NedScan) Resultaten en conclusies Het resultaat is een kort... Nederlands antropometrisch bestand (NedScan) en van lichaamsafmetingen van goedgekeurde K.L rekruten. De grenswaarden omvatten 95% van dat Nederlandse

19 CFR 10.41a - Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of international...

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Lift vans, cargo vans, shipping tanks, skids... Traffic § 10.41a Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of international traffic; repair components. (a)(1) Lift vans, cargo vans, shipping tanks, skids, pallets, caul...

19 CFR 10.41a - Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of international...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Lift vans, cargo vans, shipping tanks, skids... Traffic § 10.41a Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of international traffic; repair components. (a)(1) Lift vans, cargo vans, shipping tanks, skids, pallets, caul...

Fast Determination of the Element Excitation of an Active Phased Array Antenna

DTIC Science & Technology

1991-03-01

elementenexcitatie te, bepalen: de amplitude en fase van het elektrische ven-e veld moeten gemeten warden in slechts I richting in het verre veld van de ...Page 3 rapport no FEL-91-BO38 titel Een snelle bepaling van de excitatie van de elenienten van cen actieve phased array antenne auteur(s) I. J.G. van...van der Spek Onderzoek uItgevoerd door Ir. J.G. van Hezewijk SAMENVATIING (ONGERUBRICEERD) Het verre veld stralingsdiagram van een actieve phased array

United States Air Force Graduate Student Research Program. 1989 Program Technical Report. Volume 2

DTIC Science & Technology

1989-12-01

Patterson Air Force Base) 1. Fred Arnold 4. Jon Longtin 2. Duane Daddis 5. John McCord 3. Robert Gabruk 6. Scott VanDam ARMAMENT LABORATORY (ATL) ( Eglin Air...Report as Dr. Beryl Barber *** Engineering and Services Center 22 Effects of Jet Aircraft Noise on Jon Zern Domestic Goats 23 Contaminant Flux...Pertaining to Ground Water Contamination and Laboratory Quality Control *** Same Report as Dr. Barbara Alvin * School of Aerospace Medicine 93

The Coming Decade: American Women and Human Resources Policies and Programs, 1979. Hearings before the Committee on Labor and Human Resources, United States Senate, Ninety-Sixth Congress, 1st Session, Part 2.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. Senate Subcommittee on Labor and Human Resources.

Proceedings are presented of hearings before the Senate Committee on Labor and Human Resources to examine the conditions and opportunities confronting American women in the workplace and how government policies and programs have aided or restricted women. Among those testifying were Clara Allen and Stanley Van Ness on employment, the plight of the…

Amino acid substitutions in the VanS sensor of the VanA-type vancomycin-resistant Enterococcus strains result in high-level vancomycin resistance and low-level teicoplanin resistance.

PubMed

Hashimoto, Y; Tanimoto, K; Ozawa, Y; Murata, T; Ike, Y

2000-04-15

The vancomycin-resistant enterococci GV1, GV2 and GV3, which were isolated from droppings from broiler farms in Japan have been characterized as VanA-type VRE, which express high-level vancomycin resistance (256 or 512 microg ml(-1), MIC) and low-level teicoplanin resistance (1 or 2 microg ml(-1), MIC). The vancomycin resistances were encoded on plasmids. The vancomycin resistance conjugative plasmid pMG2 was isolated from the GV2 strain. The VanA determinant of pMG2 showed the same genetic organization as that of the VanA genes encoded on the representative transposon Tn1546, which comprises vanRSHAXYZ. The nucleotide sequences of all the genes, except the gene related to the vanS gene on Tn1546, were completely identical to the genes encoded on Tn1546. Three amino acid substitutions in the N-terminal region of the deduced VanS were detected in the nucleotide sequence of vanS encoded on pMG2. There were also three amino acid substitutions in the vanS gene of the GV1 and GV3 strains in the same positions as in the vanS gene of pMG2. Vancomycin induced the increased teicoplanin resistance in these strains.

Presence of the vancomycin resistance gene cluster vanC1, vanXYc, and vanT in Enterococcus casseliflavus.

PubMed

Hölzel, Christina; Bauer, Johann; Stegherr, Eva-Maria; Schwaiger, Karin

2014-04-01

The three chromosomally located clustered genes vanC1, vanXYc, and vanT confer intrinsic resistance to vancomycin and are used for species identification of Enterococcus gallinarum. In this study, 28 strains belonging to the E. gallinarum/casseliflavus group isolated from cloacal swabs from laying hens were screened for the presence of vanC1. As confirmed by species-specific multiplex PCR, 11 vanC1-positive strains were identified as E. gallinarum. Surprisingly, one yellow pigmented strain, verified as E. casseliflavus by species-specific multiplex PCR, was also vanC1 positive; vanXYc and vanT were additionally detectable in this strain. To our knowledge, this is the first report of vanC1, vanXYc, and vanT in E. casseliflavus. The minimum inhibitory concentration of vancomycin was 4 mg/L. Real-time reverse transcription-PCR revealed that none of the clustered genes was expressed in this strain. Even if the genes seem not to be active, there is a certain risk that they will be transferred to other bacteria where they might be functionally expressed. Therefore, it may be advisable to expand the search for vanC1, vanXYc, and vanT from E. gallinarum to other (enterococcal) species. This study confirms that enterococci live up to their name as being reservoir bacteria and should therefore always be closely monitored.

Laboratory manual: mineral X-ray diffraction data retrieval/plot computer program

USGS Publications Warehouse

Hauff, Phoebe L.; VanTrump, George

1976-01-01

The Mineral X-Ray Diffraction Data Retrieval/Plot Computer Program--XRDPLT (VanTrump and Hauff, 1976a) is used to retrieve and plot mineral X-ray diffraction data. The program operates on a file of mineral powder diffraction data (VanTrump and Hauff, 1976b) which contains two-theta or 'd' values, and intensities, chemical formula, mineral name, identification number, and mineral group code. XRDPLT is a machine-independent Fortran program which operates in time-sharing mode on a DEC System i0 computer and the Gerber plotter (Evenden, 1974). The program prompts the user to respond from a time-sharing terminal in a conversational format with the required input information. The program offers two major options: retrieval only; retrieval and plot. The first option retrieves mineral names, formulas, and groups from the file by identification number, by the mineral group code (a classification by chemistry or structure), or by searches based on the formula components. For example, it enables the user to search for minerals by major groups (i.e., feldspars, micas, amphiboles, oxides, phosphates, carbonates) by elemental composition (i.e., Fe, Cu, AI, Zn), or by a combination of these (i.e., all copper-bearing arsenates). The second option retrieves as the first, but also plots the retrieved 2-theta and intensity values as diagrammatic X-ray powder patterns on mylar sheets or overlays. These plots can be made using scale combinations compatible with chart recorder diffractograms and 114.59 mm powder camera films. The overlays are then used to separate or sieve out unrelated minerals until unknowns are matched and identified.

The Local Group in LCDM - Shapes and masses of dark halos

NASA Astrophysics Data System (ADS)

Vera-Ciro, Carlos Andrés

2013-01-01

In dit proefschrift bestuderen we de eigenschappen van donkere materie halo's in het LCDM paradigma. Het eerste deel richt zich op de vorm van de massadistributie van dergelijke objecten. We hebben gevonden dat de vorm van ge"isoleerde Melkweg-achtige donkere materie halo's significant afwijkt van bolsymmetrie. De lokale omgeving heeft invloed op de halo's en deze worden daarbij sterk be"invloed door de manier waarop massa aangroeit. We hebben ook de structuur en de baanstructuur van de satellieten van dergelijke halo's in detail onderzocht. In het algemeen zijn deze objecten sferischer dan de halo's zelf. Ze vertonen ook duidelijke afdrukken van getijdenwerking in zowel hun geometrische vorm als in de baanstructuur. Daarna gebruiken we het aantal massieve objecten rond de Melkweg om limieten te zetten op de totale massa van de donkere materie halo van de Melkweg. De eigenschappen van de massaverdeling van de Melkweg worden verder onderzocht in het laatste hoofdstuk. Daar maken we gebruik van de Sagittarius sterstroom om de vorm van de galactische potentiaal beter te bepalen. We komen met een nieuw model dat rekening houdt met de galactische schijf en de invloed van satellietstelsels en die bovendien consistent is met het LCDM paradigma.

Co-colonization of vanA and vanB Enterococcus faecium of clonal complex 17 in a patient with bacteremia due to vanA E. faecium.

PubMed

Seol, Chang Ahn; Park, Jeong Su; Sung, Heungsup; Kim, Mi-Na

2014-06-01

A 53-year-old Vietnamese man with liver cirrhosis was transferred from a Vietnamese hospital to our tertiary care hospital in Korea in order to undergo a liver transplantation. Bacteremia due to vanA Enterococcus faecium was diagnosed, and stool surveillance cultures for vancomycin-resistant enterococci (VRE) were positive for both vanA and vanB E. faecium. Pulsed-field gel electrophoresis analysis revealed that the 2 vanA VRE isolates from the blood and stool were clonal, but the vanB VRE was unrelated to the vanA VRE. vanA and vanB VRE were ST64 and ST18, single-allele variations of clonal complex 17, respectively. This is the first case report of vanA VRE bacteremia in a Vietnamese patient and demonstrates the reemergence of vanB VRE since a single outbreak occurred 15years ago in Korea. The reemergence of vanB VRE emphasizes the importance of VRE genotyping to prevent the spread of new VRE strains. Copyright © 2014 Elsevier Inc. All rights reserved.

Biochemical and Genetic Characterization of the vanC-2 Vancomycin Resistance Gene Cluster of Enterococcus casseliflavus ATCC 25788

PubMed Central

Dutta, Ireena; Reynolds, Peter E.

2002-01-01

The vanC-2 cluster of Enterococcus casseliflavus ATCC 25788 consisted of five genes (vanC-2, vanXYC-2, vanTC-2, vanRC-2, and vanSC-2) and shared the same organization as the vanC cluster of E. gallinarum BM4174. The proteins encoded by these genes displayed a high degree of amino acid identity to the proteins encoded within the vanC gene cluster. The putative d,d-dipeptidase-d,d-carboxypeptidase, VanXYC-2, exhibited 81% amino acid identity to VanXYC, and VanTC-2 displayed 65% amino acid identity to the serine racemase, VanT. VanRC-2 and VanSC-2 displayed high degrees of identity to VanRC and VanSC, respectively, and contained the conserved residues identified as important to their function as a response regulator and histidine kinase, respectively. Resistance to vancomycin was expressed inducibly in E. casseliflavus ATCC 25788 and required an extended period of induction. Analysis of peptidoglycan precursors revealed that UDP-N-acetylmuramyl-l-Ala-δ-d-Glu-l-Lys-d-Ala-d-Ser could not be detected until several hours after the addition of vancomycin, and its appearance coincided with the resumption of growth. The introduction of additional copies of the vanTC-2 gene, encoding a putative serine racemase, and the presence of supplementary d-serine in the growth medium both significantly reduced the period before growth resumed after addition of vancomycin. This suggested that the availability of d-serine plays an important role in the induction process. PMID:12234834

Characterisation of the selective binding of antibiotics vancomycin and teicoplanin by the VanS receptor regulating type A vancomycin resistance in the enterococci.

PubMed

Hughes, C S; Longo, E; Phillips-Jones, M K; Hussain, R

2017-08-01

A-type resistance towards "last-line" glycopeptide antibiotic vancomycin in the leading hospital acquired infectious agent, the enterococci, is the most common in the UK. Resistance is regulated by the VanR A S A two-component system, comprising the histidine sensor kinase VanS A and the partner response regulator VanR A . The nature of the activating ligand for VanS A has not been identified, therefore this work sought to identify and characterise ligand(s) for VanS A . In vitro approaches were used to screen the structural and activity effects of a range of potential ligands with purified VanS A protein. Of the screened ligands (glycopeptide antibiotics vancomycin and teicoplanin, and peptidoglycan components N-acetylmuramic acid, D-Ala-D-Ala and Ala-D-y-Glu-Lys-D-Ala-D-Ala) only glycopeptide antibiotics vancomycin and teicoplanin were found to bind VanS A with different affinities (vancomycin 70μM; teicoplanin 30 and 170μM), and were proposed to bind via exposed aromatic residues tryptophan and tyrosine. Furthermore, binding of the antibiotics induced quicker, longer-lived phosphorylation states for VanS A , proposing them as activators of type A vancomycin resistance in the enterococci. Copyright © 2017 Diamond Light Source Ltd. Published by Elsevier B.V. All rights reserved.

A 600,000 year long continental pollen record from Lake Van, eastern Turkey

NASA Astrophysics Data System (ADS)

Litt, T.; Pickarski, N.; Heumann, G.

2014-12-01

Lake Van is the fourth largest terminal lake in the world (38.5°N, 43 °E, volume 607 km3, area 3570 km2, maximum water depth 460 m), extending for 130 km WSW-ENE on the Eastern Anatolian High Plateau, Turkey. The sedimentary record of Lake Van, partly laminated, obtains a long and continuous continental sequence that covers multiple interglacial-glacial cycles. Promoted by the potential of the sedimentary sequence for reconstructing the paleoecological and paleoclimate development of the Near East, a deep drilling operation was carried out in 2010 supported by the International Continental Scientific Drilling Program (ICDP). The 119 m long continental record is based on a well-dated composite profile drilled on the so-called Ahlat Ridge in water depth of 360 m encompassing the last 600,000 years. It contains the longest continuous continental pollen record of the Quaternary in the entire Near East and central Asia obtained to date. It documents glacial and interglacial stages as well as pronounced interstadials encompassing the entire 600 ka of the sedimentary record. The cold-adapted vegetation in the Lake Van region during glacial stages and stadial substages can be described as dwarf-shrub steppe and desert steppe very similar to each other. The climax vegetation of the interglacial stages in the Lake Van region is characterized by an oak steppe-forest with pistachio and juniper. It is interesting to note that, in contrast to the atmospheric CO2 concentration from Antarctic ice cores or marine isotope values based on benthic foraminifera, there is no clear subdivision in the Lake Van pollen record between low-amplitude interglacials (cooler cycles) prior the mid-Brunhes event (MBE) at 430 ka and high-amplitude, post MBE interglacials. Lower CO2 concentrations in the atmosphere might be compensated by stronger insolation forcing during Marine Isotope Stages (MIS) 13a and 15a. A similar pattern can be observed during the triplicate interglacial complex MIS 7 when AP and oak values reach maximum values during MIS 7c instead of MIS 7e. This underlines the different environmental response to global climate change in the continental Lake Van region compared to the global ice volume and/or greenhouse-gas amounts.

Members of the Genera Paenibacillus and Rhodococcus Harbor Genes Homologous to Enterococcal Glycopeptide Resistance Genes vanA and vanB

PubMed Central

Guardabassi, L.; Christensen, H.; Hasman, H.; Dalsgaard, A.

2004-01-01

Genes homologous to enterococcal glycopeptide resistance genes vanA and vanB were found in glycopeptide-resistant Paenibacillus and Rhodococcus strains from soil. The putative d-Ala:d-Lac ligase genes in Paenibacillus thiaminolyticus PT-2B1 and Paenibacillus apiarius PA-B2B were closely related to vanA (92 and 87%) and flanked by genes homologous to vanH and vanX in vanA operons. PMID:15561881

Members of the genera Paenibacillus and Rhodococcus harbor genes homologous to enterococcal glycopeptide resistance genes vanA and vanB.

PubMed

Guardabassi, L; Christensen, H; Hasman, H; Dalsgaard, A

2004-12-01

Genes homologous to enterococcal glycopeptide resistance genes vanA and vanB were found in glycopeptide-resistant Paenibacillus and Rhodococcus strains from soil. The putative D-Ala:D-Lac ligase genes in Paenibacillus thiaminolyticus PT-2B1 and Paenibacillus apiarius PA-B2B were closely related to vanA (92 and 87%) and flanked by genes homologous to vanH and vanX in vanA operons.

Biochemical and genetic characterization of the vanC-2 vancomycin resistance gene cluster of Enterococcus casseliflavus ATCC 25788.

PubMed

Dutta, Ireena; Reynolds, Peter E

2002-10-01

The vanC-2 cluster of Enterococcus casseliflavus ATCC 25788 consisted of five genes (vanC-2, vanXY(C-2), vanT(C-2), vanR(C-2), and vanS(C-2)) and shared the same organization as the vanC cluster of E. gallinarum BM4174. The proteins encoded by these genes displayed a high degree of amino acid identity to the proteins encoded within the vanC gene cluster. The putative D,D-dipeptidase-D,D-carboxypeptidase, VanXY(C-2), exhibited 81% amino acid identity to VanXY(C), and VanT(C-2) displayed 65% amino acid identity to the serine racemase, VanT. VanR(C-2) and VanS(C-2) displayed high degrees of identity to VanR(C) and VanS(C), respectively, and contained the conserved residues identified as important to their function as a response regulator and histidine kinase, respectively. Resistance to vancomycin was expressed inducibly in E. casseliflavus ATCC 25788 and required an extended period of induction. Analysis of peptidoglycan precursors revealed that UDP-N-acetylmuramyl-L-Ala-delta-D-Glu-L-Lys-D-Ala-D-Ser could not be detected until several hours after the addition of vancomycin, and its appearance coincided with the resumption of growth. The introduction of additional copies of the vanT(C-2) gene, encoding a putative serine racemase, and the presence of supplementary D-serine in the growth medium both significantly reduced the period before growth resumed after addition of vancomycin. This suggested that the availability of D-serine plays an important role in the induction process.

Learning in Retirement Peer Instructors: In over Their Heads or Swimming Comfortably?

ERIC Educational Resources Information Center

Erickson, Diane

2009-01-01

The lengthening span of retirement, combined with projections of a growing aging population, has made the retirement population an increasingly important consumer group in education (Van der Kamp & Scheeren, 1997). In the 1960s, educational programming efforts for seniors were grounded in assumptions of decline. These assumptions, and a life…

African American Teacher Candidates' Experiences in Teaching Secondary Physical Education

ERIC Educational Resources Information Center

Sato, Takahiro; Hodge, Samuel Russell

2017-01-01

The purpose of this study was to describe and explain the teaching experiences of African American physical education teacher candidates in secondary physical education programs at urban schools. The research design was explanatory multiple-case study situated in positioning theory (Harré & van Langenhove, 1999). The participants were seven…

Debugging and Analysis of Large-Scale Parallel Programs

DTIC Science & Technology

1989-09-01

Przybylski, T. Riordan , C. Rowen, and D. Van’t Hof, "A CMOS RISC Processor with Integrated System Functions," In Proc. of the 1986 COMPCON. IEEE, March 1986...Sequencers," Communications of the ACM, 22(2):115-123, 1979. 115 [Richardson, 1988] Rick Richardson, "Dhrystone 2.1 Benchmark," Usenet Distribution

Building on People's Strengths: Early Childhood in Africa.

ERIC Educational Resources Information Center

Cohen, Ruth; And Others

This report describes early childhood development (ECD) in Africa and the Bernard van Leer Foundation's strategies for early childhood programs in African nations. Chapter 1 examines the context in which Africa's children are growing up, focusing on the hardships that many children face, as well as the efforts made by families, communities, and…

Paths to Empowerment. Ten Years of Early Childhood Work in Israel.

ERIC Educational Resources Information Center

Paz, Ruth

In this book, Bernard van Leer Foundation programs in Israel that combined early childhood education and community development approaches across a 10-year period are described. Chapter (1) provide an introduction; (2) discuss the evolution of this combined approach, its theoretical roots in the separate disciplines of early childhood education and…

Romanticizing Culture: The Role of Teachers' Cultural Intelligence in Working with Diversity

ERIC Educational Resources Information Center

Molina, Sarina Chugani

2013-01-01

As the world is becoming increasingly flat (Ang, Van Dyne, Koh, Templer, & Chandrasekar, 2007; Darling-Hammond, 2010; Friedman, 2005), the classroom has become a mirror that often reflects this phenomenon at a microcosmic level. As such, teacher preparation programs are continuing to emphasize the importance of understanding and valuing…

EFNEP Reaches Refugee Youth Using a Mobile Van

ERIC Educational Resources Information Center

Gossett, Linda S.

2012-01-01

New groups of refugees settled in apartments far from city services. Their children lacked access to organized after-school activities and the opportunity to practice English. The Expanded Food and Nutrition Education Program (EFNEP) wanted to reach and teach the young refugees but lacked the staff and budget to do so. This article discusses how…

Third Culture Kids and College Support: A Case Study

ERIC Educational Resources Information Center

Holdren, Sarah Jennifer

2013-01-01

This single site case study applies the "Transition Cycle" framework (Pollock & Van Reken, 2009) to an institutionally-based, student-run support program for Third Culture Kids. The purpose of this study was to examine how Lewis and Clark College responded to the presence of Third Culture Kid, or Global Nomad, students on campus by…

Incidence of Acute Kidney Injury among Patients Treated with Piperacillin-Tazobactam or Meropenem in Combination with Vancomycin.

PubMed

Rutter, W Cliff; Burgess, David S

2018-07-01

Acute kidney injury (AKI) increases during empirical antimicrobial therapy with the combination of piperacillin-tazobactam (TZP) and vancomycin (VAN) compared to the number of incidences with monotherapy or the combination of cefepime and VAN. Limited data regarding the impact of meropenem (MEM) combined with VAN exist. This study examined the AKI incidence among patients treated with MEM plus VAN (MEM+VAN) or TZP+VAN. Data were collected from the University of Kentucky Center for Clinical and Translational Science Enterprise Data Trust from September 2007 through October 2015. Adults without previous renal disease who received MEM+VAN or TZP+VAN for at least 2 days were included. AKI was assessed using risk, injury, failure, loss, and end-stage (RIFLE) criteria. Inverse probability of treatment weighting was utilized to control for differences between groups. In total, 10,236 patients met inclusion criteria, with 9,898 receiving TZP+VAN and 338 receiving MEM+VAN. AKI occurred in 15.4% of MEM+VAN patients and in 27.4% of TZP+VAN patients ( P < 0.001). TZP+VAN was associated with increased AKI compared to the level with MEM+VAN (odds ratio [OR], 2.53; 95% confidence interval [CI], 1.82 to 3.52), after controlling for confounders. Use of MEM+VAN should be considered an appropriate alternative therapy to TZP+VAN if nephrotoxicity is a major concern. The results of this study demonstrate that judicial use of TZP+VAN for empirical coverage of infection is needed. Copyright © 2018 American Society for Microbiology.

Revision of the subfamily Opiinae (Hymenoptera, Braconidae) from Hunan (China), including thirty-six new species and two new genera

PubMed Central

Li, Xi-Ying; van Achterberg, Cornelis; Tan, Ji-Cai

2013-01-01

Abstract The species of the subfamily Opiinae (Hymenoptera: Braconidae) from Hunan (Oriental China) are revised and illustrated. Thirty-six new species are described: Apodesmia bruniclypealis Li & van Achterberg, sp. n., Apodesmia melliclypealis Li & van Achterberg, sp. n., Areotetes albiferus Li & van Achterberg, sp. n., Areotetes carinuliferus Li & van Achterberg, sp. n., Areotetes striatiferus Li & van Achterberg, sp. n., Coleopioides diversinotum Li & van Achterberg, sp. n., Coleopioides postpectalis Li & van Achterberg, sp. n., Fopius dorsopiferus Li, van Achterberg & Tan, sp. n., Indiopius chenae Li & van Achterberg, sp. n., Opiognathus aulaciferus Li & van Achterberg, sp. n., Opiognathus brevibasalis Li & van Achterberg, sp. n., Opius crenuliferus Li & van Achterberg, sp. n., Opius malarator Li, van Achterberg & Tan, sp. n., Opius monilipalpis Li & van Achterberg, sp. n., Opius pachymerus Li & van Achterberg, sp. n., Opius songi Li & van Achterberg, sp. n., Opius youi Li & van Achterberg, sp. n., Opius zengi Li & van Achterberg, sp. n., Phaedrotoma acuticlypeata Li & van Achterberg, sp. n., Phaedrotoma angiclypeata Li & van Achterberg, sp. n., Phaedrotoma antenervalis Li & van Achterberg, sp. n., Phaedrotoma depressiclypealis Li & van Achterberg, sp. n., Phaedrotoma flavisoma Li & van Achterberg, sp. n., Phaedrotoma nigrisoma Li & van Achterberg, sp. n., Phaedrotoma protuberator Li & van Achterberg, sp. n., Phaedrotoma rugulifera Li & van Achterberg, sp. n., Li & van Achterberg,Phaedrotoma striatinota Li & van Achterberg, sp. n., Phaedrotoma vermiculifera Li & van Achterberg, sp. n., Rhogadopsis latipennis Li & van Achterberg, sp. n., Rhogadopsis longicaudifera Li & van Achterberg, sp. n., Rhogadopsis maculosa Li, van Achterberg & Tan, sp. n., Rhogadopsis obliqua Li & van Achterberg, sp. n., Rhogadopsis sculpturator Li & van Achterberg, sp. n., Utetes longicarinatus Li & van Achterberg, sp. n. and Xynobius notauliferus Li & van Achterberg, sp. n. Areotetes van Achterberg & Li, gen. n. (type species: Areotetes carinuliferus sp. n.) and Coleopioides van Achterberg & Li, gen. n. (type species: Coleopioides postpectalis sp. n. are described. All species are illustrated and keyed. In total 30 species of Opiinae are sequenced and the cladograms are presented. Neopius Gahan, 1917, Opiognathus Fischer, 1972, Opiostomus Fischer, 1972, and Rhogadopsis Brèthes, 1913, are treated as a valid genera based on molecular and morphological differences. Opius vittata Chen & Weng, 2005 (not Opius vittatus Ruschka, 1915), Opius ambiguus Weng & Chen, 2005 (not Wesmael, 1835) and Opius mitis Chen & Weng, 2005 (not Fischer, 1963) are primary homonymsandarerenamed into Phaedrotoma depressa Li & van Achterberg, nom. n., Opius cheni Li & van Achterberg, nom. n. andOpius wengi Li & van Achterberg, nom. n., respectively. Phaedrotoma terga (Chen & Weng, 2005) comb. n.,Diachasmimorpha longicaudata (Ashmead, 1905) and Biosteres pavitita Chen & Weng, 2005, are reported new for Hunan, Opiostomus aureliae (Fischer, 1957) comb. n. is new for China and Hunan; Xynobius maculipennis(Enderlein, 1912) comb. n. is new for Hunan and continental China and Rhogadopsis longuria (Chen & Weng, 2005) comb. n. is new for Hunan. The following new combinations are given: Apodesmia puncta (Weng & Chen, 2005) comb. n., Apodesmia tracta (Weng & Chen, 2005) comb. n., Areotetes laevigatus (Weng & Chen, 2005) comb. n., Phaedrotoma dimidia (Chen & Weng, 2005) comb. n., Phaedrotoma improcera (Weng & Chen, 2005) comb. n., Phaedrotoma amputata (Weng & Chen, 2005) comb. n., Phaedrotoma larga (Weng & Chen, 2005) comb. n., Phaedrotoma osculas (Weng & Chen, 2005) comb. n., Phaedrotoma postuma (Chen & Weng, 2005) comb. n., Phaedrotoma rugulosa (Chen & Weng, 2005) comb. n., Phaedrotoma tabularis (Weng & Chen, 2005) comb. n., Rhogadopsis apii (Chen & Weng, 2005) comb. n., Rhogadopsis dimidia (Chen & Weng, 2005) comb. n., Rhogadopsis diutia (Chen & Weng, 2005) comb. n., Rhogadopsis longuria (Chen & Weng, 2005) comb. n., Rhogadopsis pratellae(Weng & Chen, 2005) comb. n., Rhogadopsis pratensis (Weng & Chen, 2005) comb. n., Rhogadopsis sculpta (Chen & Weng, 2005) comb. n., Rhogadopsis sulcifer (Fischer, 1975) comb. n., Rhogadopsis tabidula(Weng & Chen, 2005) comb. n., Xynobius complexus (Weng & Chen, 2005) comb. n., Xynobius indagatrix (Weng & Chen, 2005) comb. n., Xynobius multiarculatus (Chen & Weng, 2005) comb. n. The following (sub)genera are synonymised: Snoflakopius Fischer, 1972, Jucundopius Fischer, 1984, Opiotenes Fischer, 1998, and Oetztalotenes Fischer, 1998, with Opiostomus Fischer, 1971; Xynobiotenes Fischer, 1998, with Xynobius Foerster, 1862; Allotypus Foerster, 1862, Lemnaphilopius Fischer, 1972, Agnopius Fischer, 1982, and Cryptognathopius Fischer, 1984, with Apodesmia Foerster, 1862; Nosopoea Foerster, 1862, Tolbia Cameron, 1907, Brachycentrus Szépligeti, 1907, Baeocentrum Schulz, 1911, Hexaulax Cameron, 1910, Coeloreuteus Roman, 1910, Neodiospilus Szépligeti, 1911, Euopius Fischer, 1967, Gerius Fischer, 1972, Grimnirus Fischer, 1972, Hoenirus Fischer, 1972, Mimirus Fischer, 1972, Gastrosema Fischer, 1972, Merotrachys Fischer, 1972, Phlebosema Fischer, 1972, Neoephedrus Samanta, Tamili, Saha & Raychaudhuri, 1983, Adontopius Fischer, 1984, Kainopaeopius Fischer, 1986, Millenniopius Fischer, 1996, and Neotropopius Fischer, 1999, with Phaedrotoma Foerster, 1862. PMID:23653521

Helicopter rotor loads using matched asymptotic expansions: User's manual

NASA Technical Reports Server (NTRS)

Pierce, G. A.; Vaidyanathan, A. R.

1983-01-01

Computer programs were developed to implement the computational scheme arising from Van Holten's asymptotic method for calculating airloads on a helicopter rotor blade in forward flight, and a similar technique which is based on a discretized version of the method. The basic outlines of the two programs are presented, followed by separate descriptions of the input requirements and output format. Two examples illustrating job entry with appropriate input data and corresponding output are included. Appendices contain a sample table of lift coefficient data for the NACA 0012 air foil and listings of the two programs.

Aquila Remotely Piloted Vehicle System Technology Demonstration (RPV-STD) Program. Volume 3. Field Test Program

DTIC Science & Technology

1979-04-01

RC pilot In the stablied RC mode. To facilitate theme attempts, an automobile , with Its headlights on high beam, was positioned on each side of the...the vans. At approxi- mately 2 to 3 km, the actual automobile headlights would become visible. Then, the operator would attempt to reposition the RPV...to line up between the head- lights. Even though the front wheels of the automobiles were elevated, the automobile headlights were diverted slightly

Scatterometry

NASA Astrophysics Data System (ADS)

Stoffelen, Adrianus Cornelis Maria

1996-10-01

Een veelheid aan meteorologische metingen is dagelijks beschikbaar. De meeste van deze waarnemingen bevinden zich echter boven land, en met name windwaarnemingen boven de (Noord Atlantische) oceaan zijn schaars. Bij een westelijke luchtstroming is dit een duidelijke beperking voor de weers- en golfverwachtingen ten behoeve van Nederland. Juist dan is het gevaar voor bijvoorbeeld storm of overstroming het grootst. Ook in het aardse klimaatsysteem speelt de wind aan het oppervlak een grote rol en is de belangrijkste factor voor de aandrijving van de oceaancirculatie. De oceaancirculatie op zijn beurt is cruciaal voor de verschijnselen die samenhangen met bijvoorbeeld El Niño. Dit proefschift gaat over het scatterometer instrument dat vanuit de ruimte, zelfs onder een wolkendek, nauwkeurige en betrouwbare informatie geeft over de wind aan het oceaanoppervlak met een hoge mate van ruimtelijke consistentie. Tijdens de tweede wereldoorlog werden radars aan boord van schepen veelvuldig gebruikt voor de opsporing van vijandige vaartuigen. Hierbij werd vastgesteld dat de detectie slechter werd naarmate de wind aan het zeeoppervlak groter was. Proefondervindelijk was hiermee het principe van een wind scatterometer aangetoond. Al snel ontwikkelde zich dan ook de idee de wind aan het zeeoppervlak te meten met behulp van radar. Vanuit een vliegtuig of een satelliet word dan een microgolfbundel onder een schuine hoek naar het zeeoppervlak gestuurd. De microgolfstraling, met gewoonlijk een golflengte van enkele centimeters, wordt verstrooid aan het ruwe oppervlak, en een klein gedeelte van de uitgezonden puls keert terug naar het detectorgedeelte van de scatterometer. Het fysische fenomeen van belang voor de werking van de scatterometer is de aanwezigheid van zogeheten capillaire gavitatiegolven op het zeeoppervlak. Deze golven hebben een golflengte van enkele centimeters en reageren vrijwel instantaan op de sterkte van de wind. De verstrooiing van microgolven is op zijn beurt weer sterk afhankelijk van de amplitude van de capillaire golven. Bovendien blijken de capillaire golfjes over het algemeen gericht in lijn met de windrichting. Aldus bestaat er een verband tussen de hoeveelheid teruggestrooide energie en de windsterkte en -richting op enige hoogte. Een scatterometer instrument wordt zo ontworpen dat uit diverse metingen van het teruggestrooide vermogen, windsterkte en -richting afgeleid kunnen worden. Deze metingen kunnen dan eenvoudig vergeleken worden met bestaande windgegevens van boeien, schepen en weermodellen ter calibratie en validatie.?SAMENVATTING viii Overzicht In de loop der jaren zijn scatterometer instrumenten aan boord van verscheidene satellieten gelanceerd. De scatterometers op de ERS-1 en ERS-2 ("European Remote-sensing Satellite") hebben de langste staat van dienst en zijn sinds 1991 operationeel. Deze scatterometers (die identiek zijn) hebben ieder drie antennes, waarmee het oceaanoppervlak in drie verschillende richtingen bemeten wordt. Een punt op het aardoppervlak wordt eerst door de naar voren gerichte bundel belicht, dan door de naar opzij gerichte bundel, en als laatste door de naar achteren gerichte bundel. De drie metingen, verder kortweg aangeduid als trits, kunnen tegen elkaar worden uitgezet, hetgeen resulteert in een ruimtelijk (3D) plaatje. Door uitgekiende doorsneden te maken van deze ruimte kan de samenhang van de drie metingen kwalitatief worden bestudeerd. De drie metingen blijken dan inderdaad een sterke samenhang te vertonen die verklaard kan worden uit twee geofysische parameters. De drie metingen liggen namelijk in het algemeen dichtbij een hoornvormig (2D) oppervlak. De lengterichting van de hoorn blijkt voornamelijk te corresponderen met een variërende windsterkte (of ruwheid van de zee), en de kortste omtrek van de hoorn met een variërende windrichting (ofwel oriëntatie van de capillaire golfjes). De karakterisatie en modellering van dit oppervlak heeft geleid tot een aanzienlijke verbetering in de interpretatie van de scatterometer, zoals beschreven is in dit proefschrift. Hierboven is een uiterst simplistisch beeld gegeven van de fysica die van belang is bij de interpretatie van de scatterometer. Het eerste hoofdstuk van dit proefschrift beschrijft in meer detail de fysische modellering van belang bij de interpretatie van de scatterometer metingen. Ten eerste, de topografie van het zeeoppervlak is uitermate gecompliceerd en niet nauwkeurig te beschrijven met eenvoudige mathematische vergelijkingen. De capillaire golven hebben een andere fasesnelheid dan de langere golven en beide hebben hiermee een ingewikkelde dynamische interactie. Bij hogere windsnelheid breken de golven en ontstaan er schuimkoppen, hetgeen de fysische beschrijving verder compliceert. Ten tweede, de interactie van een schuin invallende microgolfbundel met dit gecompliceerde oppervlak is evenmin nauwkeurig te beschrijven. Zowel verstrooiing als reflectie kunnen een rol spelen. Ten derde, over de relatie tussen de amplitude van de capillaire golven en de wind op enige hoogte, laten we veronderstellen 10 m, is in de literatuur niet de overeenstemming tot in het gewenste detail. Bij lage windsnelheid zouden de oppervlaktespanning of variaties in de wind variabiliteit een rol kunnen spelen. Gezien de fysische complexiteit, is het niet verwonderlijk dat voor de interpretatie van scatterometer metingen statistische methoden hun opgang gevonden hebben. Dit proefschrift gaat met name in op deze methoden, en geeft, aan de hand van vijf wetenschappelijke publicaties, een tamelijk volledig beeld van de "state-of-the-art", zoals die bereikt is met de?SAMENVATTING ix ERS scatterometers (ERS-1 vanaf 17 juli 1991 en later ERS-2 vanaf 22 november 1995). Het derde hoofdstuk behandelt de visualisatie van de gemeten tritsen in de 3D meetruimte, de bepaling van de spreiding van de metingen rond het hoornvormige oppervlak, en de schatting van de meest waarschijnlijke "werkelijke" (of ruisvrije) trits bij het hoornvormige oppervlak gegeven de metingen en hun nauwkeurigheid (inversie). De perceptie dat de metingen met grote waarschijnlijkheid dichtbij een hoornvormig oppervlak liggen, vormt essentiële a priori informatie van belang voor de inversie. Een inversieprocedure gestoeld op waarschijnlijkheidstheorie is afgeleid. Verder worden aan de hand van de structuur van het hoornvormige oppervlak indicatoren bepaald, van belang voor de kwaliteitscontrole, instrumentbewaking, en de verdere verwerking van de gegevens. In de appendix wordt een methode besproken die beschrijft hoe, aan de hand van geselecteerde windgegevens en een goed wind-microgolf verband, ofwel transfer functie, de scatterometer verstrooiingsmetingen gecalibreerd kunnen worden boven de oceaan. Het blijkt dat deze calibratie, die per antenne wordt uitgevoerd, uiterst nauwkeurig is, en, wanneer toegepast, in de 3D meetruimte de verdeling van gemeten tritsen gemiddeld dichterbij de door de transfer functie gemodelleerde hoorn brengt. Dit levert een verbetert scatterometer wind product op. De methode was met name van groot belang voor de validatie en calibratie van de ERS-2 scatterometer, voordat de instrumentele calibratie was voltooid. Met behulp van een set windgegevens uit een weermodel en hun geschatte nauwkeurigheden, passend in locatie en tijd bij een set van scatterometer metingen en hun geschatte nauwkeurigheden, kan met quasi-lineaire schattingstheorie ("Maximum Likelihood Estimation") de meest waarschijnlijke wind-microgolf transfer functie worden afgeleid. De niet-lineariteit en onnauwkeurige formulering van de transfer functie, een niet-uniforme verdeling van invoergegevens, en een inaccurate formulering van de geschatte nauwkeurigheid kunnen hier een goed resultaat in de weg staan. Een nieuwe functie, genoemd CMOD4, wordt afgeleid in hoofdstuk IV. Een eerste eis die gesteld wordt aan een transfer functie, is dat het in de 3D meetruimte nauwkeurig bij de gemeten tritsen past. Wanneer de "fit" optimaal is zal het gecombineerde effect van meetonnauwkeurigheid en inversiefout kleiner zijn dan 0.5 m s -1 in de wind vector. CMOD4 blijkt binnen deze fout bij de metingen te passen. Een tweede eis is, dat voor een onafhankelijke gegevensset, het verschil tussen de geïnverteerde scatterometer wind en de bijpassende wind van bijvoorbeeld een weermodel zo klein mogelijk is. In de praktijk blijkt dat deze tweede eis impliciet volgt uit de eerste, maar ook dat de onnauwkeurigheid van de scatterometer wind met name wordt bepaald door de associatie van een locatie op de hoorn met een wind vector. De onnauwkeurigheid in de scatterometer wind kan dan ook goed beschreven worden in het wind domein.?SAMENVATTING x In hoofdstuk V wordt dit laatste verder uitgewerkt, en wordt gestreefd naar een gedetailleerde wind calibratie met behulp van in situ gegevens. Windgegevens bevatten doorgaans een relatief grote onnauwkeurigheid. Het wordt aangetoond dat ijking of regressie van zulke gegevens niet mogelijk is in een vergelijking van twee meetsystemen, tenzij de nauwkeurigheid van één van de twee meetsystemen bekend is. In de praktijk is dit meestal niet zo. Voor deze gevallen wordt een methode voorgesteld die uitgaat van de simultane vergelijking van drie meetsystemen. In dit geval kan zowel de ijking als een foutenmodel voor de drie meetsystemen worden opgelost. Toepassing van de methode laat zien dat de scatterometer wind afgeleid met behulp van CMOD4 ruwweg 5 % te laag is, en de oppervlaktewind van het gebruikte weermodel ongeveer 5 % te hoog. Het hoornvormige oppervlak blijkt te bestaan uit twee nauw samenvallende laagjes. Wanneer de wind een component heeft in de kijkrichting van de middelste microgolfbundel wordt de ene hoorn beschreven, en wanneer de wind een component heeft tegengesteld hieraan, de andere. Uit een trits metingen (met ruis) kan dus in het algemeen niet een unieke windvector worden bepaald. Twee ongeveer tegengestelde oplossingen resulteren. Deze dubbelzinnigheid in de windrichting kan in de praktijk worden opgelost door die oplossing te kiezen die het dichtst bij een korte termijn weervoorspelling ligt. Daarna kunnen eisen worden gesteld aan de ruimtelijke consistentie van het gevonden windvector veld. Zoals beschreven in hoofdstuk V levert zo'n methode de goede oplossing in meer dan 99 % van de gevallen. Zo kan een in het algemeen kwalitatief goed windproduct worden afgeleid uit de ERS scatterometermetingen. In het tweede gedeelte van hoofdstuk V wordt ingegaan op de assimilatie van scatterometergegevens in weermodellen. Voor variationele gegevensassimilatie wordt een methode voorgesteld, waarbij de dubbelzinnige scatterometerwinden worden geassimileerd, en niet direct de terugstrooiingsmetingen. Dit vanwege het feit dat de onzekerheid in de interpretatie van de scatterometer, het best is uit te drukken als een fout in de wind. De projectie van deze fout op de microgolfmetingen is niet-lineair, en daarmee tamelijk moeilijk te verwerken binnen de context van meteorologische variationele gegevensassimilatie. Assimilatie van de dubbelzinnige wind daarentegen is tamelijk recht toe recht aan. De scatterometermetingen leiden tot een duidelijk betere analyse en korte-termijn voorspelling van het windveld boven zee. De bedekking is echter zodanig dat andere windwaarnemingen nog lang een zeer welkome aanvulling zullen zijn. Nieuwe Amerikaanse scatterometers met een grotere bedekking zijn in ontwikkeling (met name QuikSCAT en SeaWinds). Vanwege hun andere geometrie en golflengte is echter eerst ontwikkelwerk nodig om tot een gedegen interpretatie te komen. De in dit proefschrift beschreven methodologie kan een belangrijke rol spelen in de interpretatie van de gegevens van deze scatterometers. De volgende generatie Europese scatterometers (ASCAT genoemd) heeft een?SAMENVATTING xi grote bedekking en de microgolflengte en meetgeometrie van de ERS scatterometers. Hiermee zijn we op termijn verzekerd van een goed scatterometer wind product.?SAMENVATTING xii

A revision of the tribe Planitorini van Achterberg (Hymenoptera, Braconidae, Euphorinae), with description of a new genus from Australia.

PubMed

van Achterberg, Cornelis; Quicke, Donald L J; Boring, C Andrew

2017-01-01

The tribe Planitorini van Achterberg (Hymenoptera: Braconidae: Euphorinae) is revised. One new genus Paramannokeraia gen. n. (type species: P. gibsoni sp. n. ) and five new species from Australia are described and illustrated: Mannokeraia albipalpis van Achterberg, sp. n. , M. nigrita van Achterberg, sp. n. , M. punctata van Achterberg, sp. n. , Paramannokeraia gibsoni van Achterberg & Quicke, sp. n. and P. juliae van Achterberg, sp. n. The tribe Mannokeraiini van Achterberg, 1995, is synonymized with the tribe Planitorini ( syn. n. ).

A revision of the tribe Planitorini van Achterberg (Hymenoptera, Braconidae, Euphorinae), with description of a new genus from Australia

PubMed Central

van Achterberg, Cornelis; Quicke, Donald L.J.; Boring, C. Andrew

2017-01-01

Abstract The tribe Planitorini van Achterberg (Hymenoptera: Braconidae: Euphorinae) is revised. One new genus Paramannokeraia gen. n. (type species: P. gibsoni sp. n.) and five new species from Australia are described and illustrated: Mannokeraia albipalpis van Achterberg, sp. n., M. nigrita van Achterberg, sp. n., M. punctata van Achterberg, sp. n., Paramannokeraia gibsoni van Achterberg & Quicke, sp. n. and P. juliae van Achterberg, sp. n. The tribe Mannokeraiini van Achterberg, 1995, is synonymized with the tribe Planitorini (syn. n.). PMID:29290713

Consequences of the Introduction of Insensitive Munitions on Safety, Collateral Damage and Operations (consequenties van de invoering van mkm-munitie op veiligheid, gevolgschade en (internationaal) opereren

DTIC Science & Technology

2006-06-01

van de werkzaamheden In dit rapport worden de gevolgen van initiatie van munitie door een ongewilde externe stimulus beschouwd aan de hand van reele...operationele scenario’s. Dit wordt vergeleken met de gevolgen in dezelfde scenario’s, waarin gebruik is gemaakt van Minder Kwetsbare Munitie (MKM). Naast...de historie van MKM wordt uitgelegd wat Inleiding of terroristische activiteiten, maar ook door MKM is. Vervolgens worden de gevolgen Munitie en de

An SPSS implementation of the nonrecursive outlier deletion procedure with shifting z score criterion (Van Selst & Jolicoeur, 1994).

PubMed

Thompson, Glenn L

2006-05-01

Sophisticated univariate outlier screening procedures are not yet available in widely used statistical packages such as SPSS. However, SPSS can accept user-supplied programs for executing these procedures. Failing this, researchers tend to rely on simplistic alternatives that can distort data because they do not adjust to cell-specific characteristics. Despite their popularity, these simple procedures may be especially ill suited for some applications (e.g., data from reaction time experiments). A user friendly SPSS Production Facility implementation of the shifting z score criterion procedure (Van Selst & Jolicoeur, 1994) is presented in an attempt to make it easier to use. In addition to outlier screening, optional syntax modules can be added that will perform tedious database management tasks (e.g., restructuring or computing means).

Micro-Bubble Experiments at the Van de Graaff Accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sun, Z. J.; Wardle, Kent E.; Quigley, K. J.

In order to test and verify the experimental designs at the linear accelerator (LINAC), several micro-scale bubble ("micro-bubble") experiments were conducted with the 3-MeV Van de Graaff (VDG) electron accelerator. The experimental setups included a square quartz tube, sodium bisulfate solution with different concentrations, cooling coils, gas chromatography (GC) system, raster magnets, and two high-resolution cameras that were controlled by a LabVIEW program. Different beam currents were applied in the VDG irradiation. Bubble generation (radiolysis), thermal expansion, thermal convection, and radiation damage were observed in the experiments. Photographs, videos, and gas formation (O 2 + H 2) data were collected.more » The micro-bubble experiments at VDG indicate that the design of the full-scale bubble experiments at the LINAC is reasonable.« less

Genomic and expression analysis of the vanG-like gene cluster of Clostridium difficile.

PubMed

Peltier, Johann; Courtin, Pascal; El Meouche, Imane; Catel-Ferreira, Manuella; Chapot-Chartier, Marie-Pierre; Lemée, Ludovic; Pons, Jean-Louis

2013-07-01

Primary antibiotic treatment of Clostridium difficile intestinal diseases requires metronidazole or vancomycin therapy. A cluster of genes homologous to enterococcal glycopeptides resistance vanG genes was found in the genome of C. difficile 630, although this strain remains sensitive to vancomycin. This vanG-like gene cluster was found to consist of five ORFs: the regulatory region consisting of vanR and vanS and the effector region consisting of vanG, vanXY and vanT. We found that 57 out of 83 C. difficile strains, representative of the main lineages of the species, harbour this vanG-like cluster. The cluster is expressed as an operon and, when present, is found at the same genomic location in all strains. The vanG, vanXY and vanT homologues in C. difficile 630 are co-transcribed and expressed to a low level throughout the growth phases in the absence of vancomycin. Conversely, the expression of these genes is strongly induced in the presence of subinhibitory concentrations of vancomycin, indicating that the vanG-like operon is functional at the transcriptional level in C. difficile. Hydrophilic interaction liquid chromatography (HILIC-HPLC) and MS analysis of cytoplasmic peptidoglycan precursors of C. difficile 630 grown without vancomycin revealed the exclusive presence of a UDP-MurNAc-pentapeptide with an alanine at the C terminus. UDP-MurNAc-pentapeptide [d-Ala] was also the only peptidoglycan precursor detected in C. difficile grown in the presence of vancomycin, corroborating the lack of vancomycin resistance. Peptidoglycan structures of a vanG-like mutant strain and of a strain lacking the vanG-like cluster did not differ from the C. difficile 630 strain, indicating that the vanG-like cluster also has no impact on cell-wall composition.

Inelastic processes in atomic collisions involving ground state and laser-prepared atoms

NASA Astrophysics Data System (ADS)

Planje, Willem Gilles

1999-11-01

In dit proefschrift worden experimenten beschreven waarbij ionen of atomen met een bepaalde snelheid op een ensemble van doelwitatomen worden gericht. Wanneer twee deeltjes elkaar voldoende genaderd hebben, vindt er wissel- werking plaats waarbij allerlei processen kunnen optreden. Deze processen resulteren in specieke eindproducten. Kennis over de interactie tussen twee botsingspartners wordt verkregen door te bekijken welke eindproducten ontstaan, en in welke mate. Een belangrijke grootheid die van invloed is op mogelijke processen is de onderlinge snelheid van de twee kernen, oftewel de botsingssnelheid. Wanneer de botsingssnelheid voldoende klein is dan kunnen de verschillende reactiemechanismen zowel kwalitatief als kwanti- tatief vaak goed voorspeld worden door het systeem te beschouwen als een kort-stondig molecuul, opgebouwd uit de twee botsende deeltjes. De ver- schillende processen die kunnen optreden worden gekwaliceerd afhankelijk van de vorming van bepaalde eindproducten. Ruwweg de volgende indeling kan gemaakt worden: 1. de interne structuur van de eindproducten zijn identiek aan die van de beginproducten. We spreken dan van een elastische botsing. 2. e en van de deeltjes of beiden worden in een aangeslagen toestand ge- bracht (of ge¨oniseerd). Dit zijn processen waarbij de herschikte elek- tronen zich bij de oorspronkelijke kern bevinden. We spreken dan van excitatie of ionisatie. 3. e en of meerdere elektronen bevinden zich bij de andere kern na de botsing (eventueel in aangeslagen toestand). We spreken dan van elek- tronenoverdracht. In het eerste deel van deze dissertatie worden botsingsexperimenten tussen heliumionen en natriumatomen beschreven waarbij het proces van elek- tronenoverdracht wordt onderzocht. Bij dit mechanisme is het buitenste 117?Samenvatting natriumelektron betrokken. Deze kan relatief gemakkelijk `overspringen' naar het heliumion wanneer deze zich dicht in de buurt van het natrium- atoom bevindt. Het elektron kan hierbij een bepaalde (aangeslagen) toe- stand bezetten. Wij meten de bezetting van de heliumtoestanden die onder uitzending van XUV licht ( ? 58 nm) vervallen naar de heliumgrondtoe- stand. Door de lichtintensiteit te meten onderzoeken we de mate van elek- tronenoverdracht naar een selecte groep van singlet helium`eind'toestanden, namelijk He(1s2p), He(1s3s), He(1s3p) en He(1s3d). In een reactie- vergelijking ziet het mechanisme er als volgt uit: He + (1s) + ( Na(3s) Na(3p) e- -! He + Na + -! He(1s 2 ) +h(58 nm) + Na + Het experiment kent een extra dimensie door het feit dat het, in beginsel bol- symmetrische, natriumatoom een bepaalde ruimtelijk uitlijning kan worden meegegeven. Met behulp van laserlicht van een specieke frequentie en po- larisatie, wordt het buitenste natriumelektron in een aangeslagen p toestand gebracht. Het aanslaan naar deze toestand heeft als gevolg dat het valentie- elektron zich op grotere afstand van zijn kern bevindt dan voorheen. Daar- naast kan, afhankelijk van de gebruikte laserpolarisatie, het buitenste elek- tron zich nu rond de natriumkern bewegen volgens een bepaalde anisotrope verdeling, de bolsymmetrie is doorbroken. De eecten van de excitatie en ruimtelijk verdeling van dit natriumelektron op het proces van elektronen- overdracht zijn onderzocht voor botsingsenergie¨en vari¨erend van 0.5 keV tot 6.0 keV. De metingen laten zien dat het eect van laserexcitatie een bezettingstoe- name van de beschouwde singlet heliumtoestanden betekent, ongeacht de uitlijning van het natrium 3p elektron. Dit is simpelweg te begrijpen uit het feit dat het 3p natrium elektron minder sterk gebonden is en elektro- nenoverdracht makkelijker gaat. Daarnaast is de uitlijning van het aanges- lagen elektron van invloed op de elektronenoverdracht. De resultaten zijn vergeleken met berekeningen van S.E. Nielsen en T.H. Rod [13], die de elek- tronoverdracht beschrijven in een model waarbij het betrokken elektron zich beweegt in bepaalde eectieve potentiaalvelden. De goede overeenkomsten van onze metingen met de berekeningen rechtvaardigen de theoretische be- nadering van Nielsen en Rod. 118?Samenvatting In het tweede gedeelte van het proefschrift worden botsingen beschouwd tussen helium- en neonatomen. Hierbij wordt nu niet gekeken naar bots- ingsproducten die zich manifesteren door bepaald licht uit te zenden, maar een elektron emitteren met een bepaalde energie. Verschillende soorten `eind'producten kunnen elektronen uitzenden, waaronder de negatieve ion- toestanden. Het elektronenspectrum, gemeten voor dit botsingssysteem, vertoont twee pieken die het spectrum domineren bij 16.2 eV en 19.4 eV voor verschillende botsingsenergie¨en tussen de 0.35 keV en 6.0 keV. Deze piekstructuren wijzen op de vorming van de kort-levende, negatieve iontoe- standen Ne-(2p 5 3s 2 ) en He-(1s2s 2 ) ten gevolge van de overdracht van e en elektron: He 0 + Ne 0 -! He-(1s2s 2 ) +Ne + (2p 5 ) 3 10- 14 s -! He 0 (1s 2 ) +Ne + + e- (19.37 eV) He 0 + Ne 0 -! He + (1s) +Ne-(2p 5 3s 2 ) 2:5 10- 13 s -! He + (1s) +Ne 0 (2p 6 ) +e- (16.15 eV) De meetresultaten vertonen een fenomeen waarbij de bezettingen van de negatieve iontoestanden een oscillerend gedrag vertonen als functie van de botsingssnelheid. Dit duidt op interferentie tussen de twee bijna-ontaarde moleculaire toestanden [He- + Ne + ] en[He + + Ne-]. Het is echter zeer op- merkelijk dat deze oscillatie wordt waargenomen in een experiment als deze, waarin de uitgezonden elektronen worden gemeten ongeacht de afbuighoek van het heliumatoom. Dit impliceert een speciek aanslagmechanisme van de moleculaire negatieve iontoestanden. Nader beschouwing van het bots- ingssysteem laat zien dat het instantane molecuul twee overgangen moet ondergaan voordat de negatieve iontoestanden gevormd worden. Als gevolg hiervan is de snelheid waarmee het negatieve en positieve ion uit elkaar be- wegen nagenoeg onafhankelijk van de afbuighoek van het helium projectiel en is oscillatie mogelijk waarneembaar. De wisselwerking tussen de twee beschouwde moleculaire toestanden impliceert gecorreleerde overdracht van twee elektronen: He- + Ne + 2e- ! He + + Ne- Door het quasi-resonante systeem als resonant te beschouwen kan het fenomeen kwalitatief goed verklaard worden. 119?Samenvatting Inhet laatstedeelwordt de bevolkingvanauto¨oniserende natriumtoestanden bekeken in He +=0 + Na botsingen. In tegenstelling tot de voorgaande exper- imenten waarin elektronenoverdracht beschouwd werd, betreft het hier een excitatiemechanisme. De beschouwde `eind'producten, i.e. de auto¨oniserende natriumtoestanden, bestaan in het algemeen kort en gaan over naar een stabiele iontoestand onder uitzending van een elektron met een toestands- karakteristieke kinetische energie. Door de elektronenspectra te meten bij verschillende botsingsenergie¨en, wordt de bezetting van de auto¨oniserende toestanden onderzocht. Ook hier wordt het eect van laserexcitatie en laser- polarisatie van het natriumatoom op de vorming van deze toestanden, en de mate waarin, bekeken. De metingen laten zien dat zowel in He + -Na als in He 0 -Na botsingen de invloed van de ruimtelijk uitlijning van het buitenste natriumelektron op de elektronenspectra nihil is. Dit impliceert dat het betrokken 3p elektron hoofdzakelijk een passieve rol speelt in de vorming van auto¨oniserende toe- standen: het blijft hoofdzakelijk de 3p toestand bezetten als een `toeschouwer' zonder een overgang te maken naar een andere toestand. Dit wordt boven- dien bevestigd door het feit dat wanneer een fractie natriumatomen aange- slagen wordt naar de p toestand dit een even grote reductie betekent van onder meer de populatie van de auto¨oniserende toestand Na(2p 5 3s 2 ). De verwachte grote toename van Na(2p 5 3p 2 ) toestanden, in geval van Na(3p) doelwitten, is niet waargenomen. 120?121?122

Optimal low thrust geocentric transfer. [mission analysis computer program

NASA Technical Reports Server (NTRS)

Edelbaum, T. N.; Sackett, L. L.; Malchow, H. L.

1973-01-01

A computer code which will rapidly calculate time-optimal low thrust transfers is being developed as a mission analysis tool. The final program will apply to NEP or SEP missions and will include a variety of environmental effects. The current program assumes constant acceleration. The oblateness effect and shadowing may be included. Detailed state and costate equations are given for the thrust effect, oblateness effect, and shadowing. A simple but adequate model yields analytical formulas for power degradation due to the Van Allen radiation belts for SEP missions. The program avoids the classical singularities by the use of equinoctial orbital elements. Kryloff-Bogoliuboff averaging is used to facilitate rapid calculation. Results for selected cases using the current program are given.

The first report of the vanC₁ gene in Enterococcus faecium isolated from a human clinical specimen.

PubMed

Sun, Mingyue; Wang, Yue; Chen, Zhongju; Zhu, Xuhui; Tian, Lei; Sun, Ziyong

2014-09-01

The vanC₁ gene, which is chromosomally located, confers resistance to vancomycin and serves as a species marker for Enterococcus gallinarum. Enterococcus faecium TJ4031 was isolated from a blood culture and harbours the vanC₁gene. Polymerase chain reaction (PCR) assays were performed to detect vanXYc and vanTc genes. Only the vanXYc gene was found in the E. faecium TJ4031 isolate. The minimum inhibitory concentrations of vancomycin and teicoplanin were 2 µg/mL and 1 µg/mL, respectively. Real-time reverse transcription-PCR results revealed that the vanC₁ and vanXYc genes were not expressed. Pulsed-field gel electrophoresis and southern hybridisation results showed that the vanC₁ gene was encoded in the chromosome. E. faecalis isolated from animals has been reported to harbour vanC₁gene. However, this study is the first to report the presence of the vanC₁gene in E. faecium of human origin. Additionally, our research showed the vanC₁gene cannot serve as a species-specific gene of E. gallinarum and that it is able to be transferred between bacteria. Although the resistance marker is not expressed in the strain, our results showed that E. faecium could acquire the vanC₁gene from different species.

Tweede Serie Ergonomietests Lichtgewicht Bommenpakken (Second Series of Ergonomic Tests on Lightweight Bomb Disposal Suits)

DTIC Science & Technology

2007-12-01

warmtebelastingtests vast te stellen en (sit-and-reach, stand-and-reach. abductie referentiewaarden te bepalen door het van de arnen, anteflexie van de armen ...volgende, bewegingbeperkingtests: sit-and-reach, stand-and-reach. abductie van de armen , anteflexie van de armen en beperking van zicht. Bij de sit-and...gebogen op de rand van een tafel en houdt de armen zo ver mogeijk gestrekt naar voren op tafel. Daarbij wordt de afstand vanaf de rand van de tafel tot

Molecular Characterization of Enterococcus faecalis N06-0364 with Low-Level Vancomycin Resistance Harboring a Novel d-Ala-d-Ser Gene Cluster, vanL▿

PubMed Central

Boyd, David A.; Willey, Barbara M.; Fawcett, Darlene; Gillani, Nazira; Mulvey, Michael R.

2008-01-01

Enterococcus faecalis N06-0364, exhibiting a vancomycin MIC of 8 μg/ml, was found to harbor a novel d-Ala-d-Ser gene cluster, designated vanL. The vanL gene cluster was similar in organization to the vanC operon, but the VanT serine racemase was encoded by two separate genes, vanTmL (membrane binding) and vanTrL (racemase). PMID:18458129

A theoretical study of optical contact of vitreous silica

NASA Technical Reports Server (NTRS)

Barber, T. D.

1972-01-01

Optical contact has been proposed as a method of bonding quartz parts of the Stanford relativity satellite. The theory of the van der Waals force is outlined and applied to the problem of optical contact. The effect of various contaminations is discussed and a program of experimentation for further study of the problem is presented.

Case Study - Propane Bakery Delivery Step Vans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laughlin, M.; Burnham, A.

2016-04-01

A switch to propane from diesel by a major Midwest bakery fleet showed promising results, including a significant displacement of petroleum, a drop in greenhouse gases and a fuel cost savings of seven cents per mile, according to a study recently completed by the U.S. Department of Energy's Argonne National Laboratory for the Clean Cities program.

78 FR 28947 - Fund Availability Under VA's Homeless Providers Grant and Per Diem Program (VANS)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-16

... Certified Public Accountant (CPA) or letter from the United Way stating they are a member in good standing... cash and in-kind resources from other public (including Federal and State) and private sources that are... public transportation available to homeless veterans in your project. (b) Project location (e.g., is the...

Guidelines for Undergraduate Exercise Physiology in a Physical Education Teacher Education Program. Guidance Document

ERIC Educational Resources Information Center

National Association for Sport and Physical Education, 2006

2006-01-01

A course in Exercise Physiology is a common requirement among undergraduate students preparing for a career in physical education, adult fitness, or athletic training. Often, such courses are taught to an assortment of students from a variety of disciplines (Van Donselaar & Leslie, 1990) with an emphasis on physiological principles applied to…

Minnesota Innovation Research Program.

DTIC Science & Technology

1986-03-01

Petroleum, Magnetic Controls, Farm Credit Services Corporations, Bush Foundation, and Hospital Corporation of America . .. Unc lassifijed RUNOT...Paper #47 (March, 1986). 7. David Bastien, " Sociolinguistic Studies of Mergers and Acquisitions," to be presented at the Minnesota Conference on...Applied Sociolinguistics , 1986. 8. David Bastien and Andrew Van de Ven, "Managerial and Organizational Dynamics of Mergers and Acquisitions," SNRC

The Fate of Intrapleurally Injected Bone Marrow-Derived Stem Cells in Mice with Pleural Mesothelioma

DTIC Science & Technology

2012-12-01

hepatocytes by the intrahepatic delivery of clonal human mesenchymal stem cells in fetal sheep . Hepatology, 46: 1935-1945, 2007. 4. Jongsma, J., van...Mice with Pleural Mesothelioma 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-11-1-0574 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Jonathan M

Cooperating Teacher Compensation and Benefits: Comparing 1957-1958 and 2012-2013

ERIC Educational Resources Information Center

Fives, Helenrose; Mills, Tammy M.; Dacey, Charity M.

2016-01-01

We offer a comparative investigation of the compensation and benefits afforded to cooperating teachers (CTs) by teacher education programs (TEPs) in 1957-1958 and 2012-2013. This investigation replicates and extends a description of the compensation practices of 20 U.S. TEPs published by VanWinkle in 1959. Data for the present investigation came…

Families as Decision-Makers: When Researchers and Advocates Work Together

ERIC Educational Resources Information Center

Fields-Smith, Cheryl; Neuharth-Pritchett, Stacey

2009-01-01

Families across the United States must routinely make difficult choices about child care arrangements because of the need to resume a job, continue an education or training program, or care for other family members. Leaving children in the care of others for the first time can be difficult (Sayer, Bianchi, & Robinson, 2004; Van Horn, Ramey,…

From Professional Development to Classroom Instruction: Addressing Issues Related to Science Inquiry Discourse

ERIC Educational Resources Information Center

Oliveira, Alandeom W.

2009-01-01

In this rejoinder, I first provide a more detailed account of the discourse-focused professional development activities facilitated as part of the SMIT'N program, specifically addressing issues raised by van Zee with regard to the institute's overall format, goals and development strategies. Next, I resort to Peter Medawar's metaphorical view of…

Benefits of Mother Goose: Influence of a Community-Based Program on Parent-Child Attachment Relationships in Typical Families

ERIC Educational Resources Information Center

Scharfe, Elaine

2011-01-01

An estimated 50 to 60% of children from typical families develop secure attachment relationships with their parents (Ainsworth, Blehar, Waters, & Wall, 1978; Van IJzendoorn & Kroonenberg, 1988); however, intervention research has focused primarily on interventions for high-risk clinical samples (Berlin, Zeanah, & Lieberman, 2008). In this project,…

GeoJourney: A Field-Based, Interdisciplinary Approach to Teaching Geology, Native American Cultures, and Environmental Studies

ERIC Educational Resources Information Center

Elkins, Joe; Elkins, Nichole M. L.; Hemmings, Sarah N. J.

2008-01-01

GeoJourney is an interdisciplinary field trip in geology, Native American studies, and environmental studies designed for introductory-level undergraduates. The program travels 23,345 kilometers by van to national parks, industrial sites, museums, and Indian reservations in 24 of the United States. During the day, students carry out hands-on…

Iniciativa sobre Efectividad: Un entorno para el aprendizaje (Initiative about Effectiveness: An Environment for Learning).

ERIC Educational Resources Information Center

Moreno Garcia, Teresa, Ed.

2000-01-01

This Spanish- and Portuguese-language bulletin presents articles focusing on the Effectiveness Initiative (EI), a project of the Bernard van Leer Foundation for making a qualitative analysis of those elements of the programs of Early Childhood Development (ECD) that benefit the participants and their communities and cultures. The first article…

78 FR 71025 - Notice of Buy America Waiver for Minivans

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-27

... NFRMPO's vanpool (``VanGo'') program. This waiver is limited to a single purchase not to exceed 25 seven... to a single purchase not to exceed 25 seven-passenger vehicles and expires on December 31, 2014. FOR... manufacturing processes for the product must take place in the United States; and (2) All of the components of...

Finding and Understanding Talent among Elementary English Language Learners: Beyond Project Hope

ERIC Educational Resources Information Center

Pereira, Nielsen

2011-01-01

The under-identification and underrepresentation of English language learners (ELLs) in gifted programs remains a severe and pervasive problem in the field of gifted education (Yoon & Gentry, 2009, VanTassel-Baska & Stambaugh, 2007). This study focused on ELLs in grades K-5 from four elementary schools in Midwestern school districts (a) to…

19 CFR 10.41a - Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of international...

Code of Federal Regulations, 2014 CFR

2014-04-01

... for inspection by Customs officials upon reasonable notice. (3) If the container does not exit the U.S... 19 Customs Duties 1 2014-04-01 2014-04-01 false Lift vans, cargo vans, shipping tanks, skids... Traffic § 10.41a Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of...

19 CFR 10.41a - Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of international...

Code of Federal Regulations, 2012 CFR

2012-04-01

... for inspection by Customs officials upon reasonable notice. (3) If the container does not exit the U.S... 19 Customs Duties 1 2012-04-01 2012-04-01 false Lift vans, cargo vans, shipping tanks, skids... Traffic § 10.41a Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of...

19 CFR 10.41a - Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of international...

Code of Federal Regulations, 2013 CFR

2013-04-01

... for inspection by Customs officials upon reasonable notice. (3) If the container does not exit the U.S... 19 Customs Duties 1 2013-04-01 2013-04-01 false Lift vans, cargo vans, shipping tanks, skids... Traffic § 10.41a Lift vans, cargo vans, shipping tanks, skids, pallets, and similar instruments of...

First and Second Order Stokes Generation by SRS in Methane: Influence of Rep-Rate, Beam Quality and Astigmatism (Opwekking van Eerste en Tweede Orde Stokes d.m.v. SRS in Methaan: Invloed van de Pulsfrequentie, de Bundelkwaliteit en Astigmatisme)

DTIC Science & Technology

1992-09-01

omzettings rendementen van circa 75% gehaad bij een ingangs- energie van 280 mJ. De mogelijkheden tot bet halen van een hoger rendement lijken...of rep-rate, beam quality and astigmatism DImi-Thu-B~mO ITA1EiM-tT-h lF I~~ ~~’ IAPR2 8 1993~ I ~Xtbai Uiitdw FJ.M. van Putten J.C. van den Heuvel RJ.L...Influence of rep-rate. beam quality and astigmatism author(s) : F.J.M. van Putten, I.C. van den Heuvel, R.J.L. Lerou institute : TNO Physics and

Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin

PubMed Central

Phillips-Jones, Mary K.; Channell, Guy; Kelsall, Claire J.; Hughes, Charlotte S.; Ashcroft, Alison E.; Patching, Simon G.; Dinu, Vlad; Gillis, Richard B.; Adams, Gary G.; Harding, Stephen E.

2017-01-01

VanA-type resistance to glycopeptide antibiotics in clinical enterococci is regulated by the VanSARA two-component signal transduction system. The nature of the molecular ligand that is recognised by the VanSA sensory component has not hitherto been identified. Here we employ purified, intact and active VanSA membrane protein (henceforth referred to as VanS) in analytical ultracentrifugation experiments to study VanS oligomeric state and conformation in the absence and presence of vancomycin. A combination of sedimentation velocity and sedimentation equilibrium in the analytical ultracentrifuge (SEDFIT, SEDFIT-MSTAR and MULTISIG analysis) showed that VanS in the absence of the ligand is almost entirely monomeric (molar mass M = 45.7 kDa) in dilute aqueous solution with a trace amount of high molar mass material (M ~ 200 kDa). The sedimentation coefficient s suggests the monomer adopts an extended conformation in aqueous solution with an equivalent aspect ratio of ~(12 ± 2). In the presence of vancomycin over a 33% increase in the sedimentation coefficient is observed with the appearance of additional higher s components, demonstrating an interaction, an observation consistent with our circular dichroism measurements. The two possible causes of this increase in s – either a ligand induced dimerization and/or compaction of the monomer are considered. PMID:28397853

In Vivo Fluorescence Confocal Microscopy to Investigate the Role of RhoC in Inflammatory Breast Cancer

DTIC Science & Technology

2005-04-01

5084. 6. Colpaert CG, Vermeulen PB, Benoy I, Soubry A, van Roy F, van Beest P, Goovaerts G, Dirix LY, van Dam P, Fox SB, Harris AL, van MarckEA...cancer. Cancer Res 1999, 59: 5079-5084. 17 14. Colpaert CG, Vermeulen PB, Benoy I, Soubry A, van Roy F, van Beest P, Goovaerts G, Dirix LY, van Dam P...Ohira S, Feng Y, Nikaido T, Konishi I: Up- regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma. Lab

Mentale Inzetbaarheid van Teams: Ontwikkeling van een Moden van Teamfunctioneren als Module voor SCOPE (Mental Readiness of Teams - Development of a Team Model as Module for SCOPE)

DTIC Science & Technology

2007-04-01

inzetbaarheid van teams: ontwikkeling van een model van teamfunctioneren als module voor SCOPE Datumn april 2007 Auteur (s) R. de B~ruin C’. Vervvijs A.J...Datum april 2007 Programmaleider Projectleider Auteur (s) dr. W.A. Lotens, TNO Defensie en A.]. van Vijet, TNO Defensie en R. de Bruin Veiligheid...Deelnemers verwachten wel, in lijn met de theorie , dat een lage cohesie samenhangt met een lage effectiviteit. Een hoge cohesie, daarentegen, zou

User Manual PIRATE Model, Release Beta 1.0. (Handleiding PIRATE model, versie Beta 1.0)

DTIC Science & Technology

1998-01-01

Beperkingen van PIRATE 40 9 . Conclusies en aanbevelingen 41 10. Referenties 42 11 . Ondertekening 43 TNO-rapport FEL-97-A285 Inleiding Bij maritieme...Inhoud Inleiding 7 1.1 Doel van PIRATE 7 1.2 Werking van PIRATE 8 1.3 Opbouw van de handleiding 8 2. Bediening van PIRATE 9 2.1 Systeemvereisten 10...2.2 Installatie 10 2.3 Bediening van de gebruikersinterface 11 2.4 Gebruiken van de figuren in andere programmes 15 3. Radars, radars in PIRATE

Molecular epidemiology of vancomycin resistant enterococci in a tertiary care hospital in Saudi Arabia.

PubMed

Somily, Ali M; Al-Mohizea, Maha M; Absar, Muhammed M; Fatani, Amal J; Ridha, Afaaf M; Al-Ahdal, Mohammed N; Senok, Abiola C; Al-Qahtani, Ahmed A

2016-08-01

Vancomycin-resistant enterococci (VRE) are a major cause of nosocomial infections with high mortality and morbidity. There is limited data on the molecular characterization of VRE in Saudi Arabia. This study was carried out to investigate the premise that a shift in VRE epidemiology is occurring in our setting. Enterococcus species identification and susceptibility testing plus VRE phenotypic confirmation by vancomycin and teicoplanin E-test were carried out. Vancomycin resistance genes were detected by PCR. Strain typing was conducted using PFGE. Among the strains of Enterococcus spp. investigated in this study, 17 (4.5%) were VRE. With the exception of one isolate from rectal swab, all others were clinical specimens with blood being the commonest source (n = 11; 64.7%), followed by urine (n = 3; 17.6%). The 17 VRE isolates were Enterococcus faecium (n/N = 13/17) and Enterococcus gallinarum (n/N = 4/17). Among E. faecium isolates, vanA(+)/vanB(+) (n/N = 8/13; 62%) exhibiting VanB phenotype were predominant. One of the five vanA(+)E. faecium isolates exhibited a VanB phenotype indicative of vanA genotype-VanB phenotype incongruence. E. gallinarum isolates exhibited a Van C phenotype although two were vanA(+)/vanC1(+). PFGE revealed a polyclonal distribution with eight pulsotypes. These findings indicate an evolving VRE epidemiology with vanA(+)/vanB(+) isolates and vanA genotype-VanB phenotype incongruence isolates, which were previously described as colonizers, are now causing clinical infection. Copyright © 2016 Elsevier Ltd. All rights reserved.

Side-looking airborne radar image interpretation and geological mapping: Problems and results

NASA Technical Reports Server (NTRS)

Scanvic, J. Y.; Soubari, E. H.

1980-01-01

Geological experiments and surveys conducted by BRGM and GDTA members to evaluate interest in SLAR image interpretation are summarized. Two surveys were selected for presentation: Les Vans (Massif central, France) and Guyana (South America). They have permitted a comparison between different types of SLAR: Goodyear, Motorola, JPL, and Vigie in term of lithological and structural applications. On the Les Vans test site conclusions reached concern radiometry, which is better on L-band imagery, polarization, HV being more useful than HH for geological mapping in an L-band system, wavelength and illuminations. Over Guyana, the use of Goodyear X-band SLAR enables satisfactory geological and structural mapping under heavy equatorial forest with cloud cover conditions. A differential program was developed for fracture filtering and image enhancement with a coherent light laser, and significant results were obtained.

A Comparison of Van Allen Belt Radiation Environment Modeling Programs: AE8/AP8 Legacy, AE9/AP9, and SPENVIS

NASA Technical Reports Server (NTRS)

Reed, Evan; Pellish, Jonathan

2016-01-01

In the space surrounding Earth there exists an active radiation environment consisting mostly of electrons and protons that have been trapped by Earths magnetic field. This radiation, also known as the Van Allen Belts, has the potential to damage man-made satellites in orbit; thus, proper precautions must be taken to shield NASA assets from this phenomenon. Data on the Van Allen Belts has been collected continuously by a multitude of space-based instruments since the beginning of space exploration. Subsequently, using theory to fill in the gaps in the collected data, computer models have been developed that take in the orbital information of a hypothetical mission and output the expected particle fluence and flux for that orbit. However, as new versions of the modeling system are released, users are left wondering how the new version differs from the old. Therefore, we performed a comparison of three different editions of the modeling system: AE8/AP8 (legacy), which is included in the model 9 graphical user interface as an option for ones calculations, AE9/AP9, and the Space Environment Information System (SPENVIS), which is an online-based form of AE8/AP8 developed by NASA and the European Space Agency that changed the code to allow the program to extrapolate data to predict fluence and flux at higher energies. Although this evaluation is still ongoing, it is predicted that the model 8 (legacy) and SPENVIS version will have identical outputs with the exception of the extended energy levels from SPENVIS, while model 9 will provide different fluences than model 8 based on additional magnetic field descriptions and on-orbit data.

Molecular epidemiology of vancomycin-resistant enterococcal bacteraemia: results from the Canadian Nosocomial Infection Surveillance Program, 1999-2009.

PubMed

McCracken, M; Wong, A; Mitchell, R; Gravel, D; Conly, J; Embil, J; Johnston, L; Matlow, A; Ormiston, D; Simor, A E; Smith, S; Du, T; Hizon, R; Mulvey, M R

2013-07-01

Vancomycin-resistant enterococci (VRE) can be associated with serious bacteraemia. The focus of this study was to characterize the molecular epidemiology of VRE from bacteraemia cases that were isolated from 1999 to 2009 as part of Canadian Nosocomial Infection Surveillance Program (CNISP) surveillance activities. From 1999 to 2009, enterococci were collected from across Canada in accordance with the CNISP VRE surveillance protocol. MICs were determined using broth microdilution. PCR was used to identify vanA, B, C, D, E, G and L genes. Genetic relatedness was examined using multilocus sequence typing (MLST). A total of 128 cases of bacteraemia were reported to CNISP from 1999 to 2009. In 2007, a significant increase in bacteraemia rates was observed in western and central Canada. Eighty-one of the 128 bacteraemia isolates were received for further characterization and were identified as Enterococcus faecium. The majority of isolates were from western Canada (60.5%), followed by central (37.0%) and eastern (2.5%) Canada. Susceptibilities were as follows: daptomycin, linezolid, tigecycline and chloramphenicol, 100%; quinupristin/dalfopristin, 96.3%; high-level gentamicin, 71.6%; tetracycline, 50.6%; high-level streptomycin, 44.4%; rifampicin, 21.0%; nitrofurantoin, 11.1%; clindamycin, 8.6%; ciprofloxacin, levofloxacin and moxifloxacin, 1.2%; and ampicillin, 0.0%. vanA contributed to vancomycin resistance in 90.1% of isolates and vanB in 9.9%. A total of 17 sequence types (STs) were observed. Beginning in 2006 there was a shift in ST from ST16, ST17, ST154 and ST80 to ST18, ST412, ST203 and ST584. The increase in bacteraemia observed since 2007 in western and central Canada appears to coincide with the shift of MLST STs. All VRE isolates remained susceptible to daptomycin, linezolid, chloramphenicol and tigecycline.

Investigation of seismo-ionospheric effects associated with Elazig and Van earthquakes in Turkey

NASA Astrophysics Data System (ADS)

Shagimuratov, I.; Cherniak, Iu.; Zakharenkova, I.; Tepenitsyna, N.; Yakimova, G.

2012-04-01

This report presents the specific features of TEC (total electron content of the ionosphere) behavior associated with earthquakes 08 March 2010 (Elazıg, Mw 6.1) and devastating earthquake with M 7.3, occurred on 23 October 2011 in Van. For this purpose we used both the GPS TEC data from the nearest to the epicenter GPS-IGS stations and constructed TEC maps over Europe. The favorable circumstance for this analysis was the quiet geomagnetic situation during the period previous to the earthquakes (the sum of Kp didn't exceed 5 for first and less than 15 for second case). The typical anomaly was found out one week prior to Elazıg earthquake and three days prior to Van earthquake as the day-time significant increase of TEC at the nearest stations up to the value of 50% relative to the background condition. To estimate the spatial dimensions of seismo-ionospheric anomaly the differential mapping method was used. Anomalous TEC enhancement was registered since 10 UT and reached the maximal value of 45-55% at 18-20 UT. So, the seismo-ionospheric anomaly was found out as the cloud-shaped increase of total electron content of the ionosphere, it had a well-defined local character and it was situated in the immediate vicinity of the earthquake epicenter area. Acknowledgments. The authors are grateful to the IGS community for providing GPS permanent data and to the USGS Earthquake Hazards Program for the detailed earthquake information. The research leading to these results has received funding from the European Union Sevenths Framework Program (FP7/20017-2013) under grant agreement No. 263502 - PRE-EARTHQUAKES project.

Distribution and Regulation of Meloidogyne nataliei.

PubMed

Bird, G; Diamond, C; Warner, F; Davenport, J

1994-12-01

Between 1978 and 1990, eight surveys were conducted in southwest Michigan to document the occurrence of Meloidogyne nataliei, the Michigan grape root-knot nematode. The known distribution of M. nataliei is limited to a total of six sections in Antwerp and Porter Townships in Van Buren County, Michigan. In 1984, a M. nataliei regulatory program was initiated by the Michigan Department of Agriculture, U. S. Department of Agriculture Animal and Plant Health Inspection Service, and Michigan State University. The program was designed to reduce risk of damage associated with this nematode.

RpoS induces expression of the Vibrio anguillarum quorum-sensing regulator VanT.

PubMed

Weber, Barbara; Croxatto, Antony; Chen, Chang; Milton, Debra L

2008-03-01

In vibrios, regulation of the Vibrio harveyi-like LuxR transcriptional activators occurs post-transcriptionally via small regulatory RNAs (sRNAs) that destabilize the luxR mRNA at a low cell population, eliminating expression of LuxR. Expression of the sRNAs is modulated by the vibrio quorum-sensing phosphorelay systems. However, vanT mRNA, which encodes a LuxR homologue in Vibrio anguillarum, is abundant at low and high cell density, indicating that VanT expression may be regulated via additional mechanisms. In this study, Western analyses showed that VanT was expressed throughout growth with a peak of expression during late exponential growth. VanO induced partial destabilization of vanT mRNA via activation of at least one Qrr sRNA. Interestingly, the sigma factor RpoS significantly stabilized vanT mRNA and induced VanT expression during late exponential growth. This induction was in part due to RpoS repressing expression of Hfq, an RNA chaperone. RpoS is not part of the quorum-sensing regulatory cascade since RpoS did not regulate expression or activity of VanO, and RpoS was not regulated by VanO or VanT. VanT and RpoS were needed for survival following UV irradiation and for pigment and metalloprotease production, suggesting that RpoS works with the quorum-sensing systems to modulate expression of VanT, which regulates survival and stress responses.

[Styles of programming 1952-1972].

PubMed

van den Bogaard, Adrienne

2008-01-01

In the field of history of computing, the construction of the early computers has received much scholarly attention. However, these machines have not only been important because of their logical design and their engineering, but also because of the programming practices that emerged around these first machines. This article compares two styles of programming that developed around Dutch 'first computers'. The first style is represented by Edsger Wybe Dijkstra (1930-2002), who would receive the Turing Award for his work in 1972. Dijkstra developed a mathematical style of programming--a program was something you should be able to design mathematically and prove it logically. The second style is represented by Willem Louis van der Poel (born 1926). For him, programming is 'trickology'. A program is primarily a technical artefact that should work: a program is something you play with, comparable to the way one solves a puzzle.

Chlorhexidine Induces VanA-Type Vancomycin Resistance Genes in Enterococci

PubMed Central

Bhardwaj, Pooja; Ziegler, Elizabeth

2016-01-01

Chlorhexidine is a bisbiguanide antiseptic used for infection control. Vancomycin-resistant E. faecium (VREfm) is among the leading causes of hospital-acquired infections. VREfm may be exposed to chlorhexidine at supra- and subinhibitory concentrations as a result of chlorhexidine bathing and chlorhexidine-impregnated central venous catheter use. We used RNA sequencing to investigate how VREfm responds to chlorhexidine gluconate exposure. Among the 35 genes upregulated ≥10-fold after 15 min of exposure to the MIC of chlorhexidine gluconate were those encoding VanA-type vancomycin resistance (vanHAX) and those associated with reduced daptomycin susceptibility (liaXYZ). We confirmed that vanA upregulation was not strain or species specific by querying other VanA-type VRE. VanB-type genes were not induced. The vanH promoter was found to be responsive to subinhibitory chlorhexidine gluconate in VREfm, as was production of the VanX protein. Using vanH reporter experiments with Bacillus subtilis and deletion analysis in VREfm, we found that this phenomenon is VanR dependent. Deletion of vanR did not result in increased chlorhexidine susceptibility, demonstrating that vanHAX induction is not protective against chlorhexidine. As expected, VanA-type VRE is more susceptible to ceftriaxone in the presence of sub-MIC chlorhexidine. Unexpectedly, VREfm is also more susceptible to vancomycin in the presence of subinhibitory chlorhexidine, suggesting that chlorhexidine-induced gene expression changes lead to additional alterations in cell wall synthesis. We conclude that chlorhexidine induces expression of VanA-type vancomycin resistance genes and genes associated with daptomycin nonsusceptibility. Overall, our results indicate that the impacts of subinhibitory chlorhexidine exposure on hospital-associated pathogens should be further investigated in laboratory studies. PMID:26810654

Self-Management Support Program for Patients With Cardiovascular Diseases: User-Centered Development of the Tailored, Web-Based Program Vascular View.

PubMed

Puijk-Hekman, Saskia; van Gaal, Betsie Gi; Bredie, Sebastian Jh; Nijhuis-van der Sanden, Maria Wg; van Dulmen, Sandra

2017-02-08

In addition to medical intervention and counseling, patients with cardiovascular disease (CVD) need to manage their disease and its consequences by themselves in daily life. The aim of this paper is to describe the development of "Vascular View," a comprehensive, multi-component, tailored, Web-based, self-management support program for patients with CVD, and how this program will be tested in an early randomized controlled trial (RCT). The Vascular View program was systematically developed in collaboration with an expert group of 6 patients, and separately with a group of 6 health professionals (medical, nursing, and allied health care professionals), according to the following steps of the intervention mapping (IM) framework: (1) conducting a needs assessment; (2) creating matrices of change objectives; (3) selecting theory-based intervention methods and practical applications; (4) organizing methods and applications into an intervention program; (5) planning the adaption, implementation, and sustainability of the program, and (6) generating an evaluation plan. The needs assessment (Step 1) identified 9 general health problems and 8 determinants (knowledge, awareness, attitude, self-efficacy, subjective norm, intention, risk perception, and habits) of self-managing CVD. By defining performance and change objectives (Step 2), 6 topics were distinguished and incorporated into the courses included in Vascular View (Steps 3 and 4): (1) Coping With CVD and its Consequences; (2) Setting Boundaries in Daily Life; (3) Lifestyle (general and tobacco and harmful alcohol use); (4) Healthy Nutrition; (5) Being Physically Active in a Healthy Way; and (6) Interaction With Health Professionals. These courses were based on behavioral change techniques (BCTs) (eg, self-monitoring of behavior, modeling, re-evaluation of outcomes), which were incorporated in the courses through general written information: quotes from and videos of patients with CVD as role models and personalized feedback, diaries, and exercises. The adoption and implementation plan (Step 5) was set up in collaboration with the members of the two expert groups and consisted of a written and digital instruction manual, a flyer, bimonthly newsletters, and reminders by email and telephone to (re-)visit the program. The potential effectiveness of Vascular View will be evaluated (Step 6) in an early RCT to gain insight into relevant outcome variables and related effect sizes, and a process evaluation to identify intervention fidelity, potential working mechanisms, user statistics, and/or satisfaction. A comprehensive, multi-component, tailored, Web-based, self-management support program and an early RCT were developed in order to empower patients to self-manage their CVD. Nederlands Trial Register NTR5412; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=5412 (Archived by WebCite at http://www.webcitation.org/6jeUFVj40). ©Saskia Puijk-Hekman, Betsie GI van Gaal, Sebastian JH Bredie, Maria WG Nijhuis-van der Sanden, Sandra van Dulmen. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 08.02.2017.

Tussenrapportage Validatie Onderwijsvernieuwingen (Validation Assistant in Instructional Design)

DTIC Science & Technology

2007-05-01

validatie onderwij svemieuwingen D)atum mei 2007 Auteur (s) drs. J.P. van Meer drs. G,J. Veldhuis dr. M.L. van Ernmerik M.G. van Schaik Rubricering...als doel om nog beter is het van belang dat het maken van keuzes Auteur (s) passende adviezen te kunnen genereren. binnen een moeilijk grijpbaar...benaderd door de theorie achter de onderwijsconcepten te toetsen aan het oordeel van de expert. Er zijn echter beperkingen in deze opzet denkbaar die

1958 NASA/USAF Space Probes (ABLE-1). Volume 3; Vehicles, Trajectories, and Flight Histories

NASA Technical Reports Server (NTRS)

1959-01-01

The three NASA/USAF lunar probes of August 17, October 13, and November 8, 1958 are described. Details of the program, the vehicles, the payloads, the firings, the tracking, and the results are presented. Principal result was the first experimental verification of a confined radiation zone of the type postulated by Van Allen and others.

Final Supplemental Environmental Assessment: Falcon I Launch Vehicle Program from SLC-4W Vandenberg Air Force Base, California

DTIC Science & Technology

2005-09-06

affected surface water, 3) adversely affected groundwater quantity or quality, or 4) caused a need that exceeded the existing potable supply or...goby is from Tillas Slough (mouth of the Smith River) in Del Norte County, south to Colonel Louis D. Van Mullem, Jr. (1-8-96-F/C-29) 5 Agua Hedionda

Synthesis and Functionalization of Atomic Layer Boron Nitride Nanosheets for Advanced Material Applications

DTIC Science & Technology

2014-06-05

PAGES 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 5c. PROGRAM ELEMENT NUMBER 5b. GRANT NUMBER 5a. CONTRACT NUMBER Form Approved OMB...Phys., 89, (2001) 5243. [14] M. Depas, R. L. Van Meirhaegue, W. H. Laflère, F. Cardon , Solid- State Electron, 37, (1994) 433. [15] Muhammad Sajjad

Ultrafast interlayer photocarrier transfer in graphene-MoSe2 van derWaals heterostructure

NASA Astrophysics Data System (ADS)

Zhang, Xin-Wu; He, Da-Wei; He, Jia-Qi; Zhao, Si-Qi; Hao, Sheng-Cai; Wang, Yong-Sheng; Yi, Li-Xin

2017-08-01

Not Available Project supported by the National Natural Science Foundation of China (Grant Nos. 61275058, 61527817, 61335006, and 61378073), the National Science Foundation, China (Grant No. DMR-1505852), the National Basic Research Program of China (Grant Nos. 2016YFA0202300 and 2016YFA0202302), and Beijing Science and Technology Committee, China (Grant No. Z151100003315006).

FOREWORD: International Conference on Heavy Ion Collisions in the LHC Era

NASA Astrophysics Data System (ADS)

Arleo, Francois; Salgado, Carlos A.; Tran Thanh Van, Jean

2013-03-01

The International Conference on Heavy Ion Collisions in the LHC Era was held in Quy Nhon, Vietnam, on 16-20 July 2012. The series Rencontres du Vietnam, created by Jean Tran Thanh Van in 1993, consists of international meetings aimed to stimulate the development of advanced research in Vietnam and more generally in South East Asia, and to establish collaborative research networks with Western scientific communities. This conference, as the whole series, also supports the International Center for Interdisciplinary Science Education being built in Quy Nhon. The articles published in this volume present the latest results from the heavy-ion collision programs of RHIC and LHC as well as the corresponding theoretical interpretation and future perspectives. Lower energy nuclear programs were also reviewed, providing a rather complete picture of the state-of-the-art in the field. We wish to thank the sponsors of the Conference on Heavy Ion Collisions in the LHC Era: the European Research Council; Xunta de Galicia (Spain); EMMI (Germany) and Agence Nationale de la Recherche (France) François Arleo (Laboratoire d'Annecy-le-Vieux de Physique Théorique, France) Francois Arleo, Carlos A Salgado and Jean Tran Thanh Van Conference photograph

Emergence of vanA Enterococcus faecium in Denmark, 2005-15.

PubMed

Hammerum, Anette M; Baig, Sharmin; Kamel, Yasmin; Roer, Louise; Pinholt, Mette; Gumpert, Heidi; Holzknecht, Barbara; Røder, Bent; Justesen, Ulrik S; Samulioniené, Jurgita; Kjærsgaard, Mona; Østergaard, Claus; Holm, Anette; Dzajic, Esad; Søndergaard, Turid Snekloth; Gaini, Shahin; Edquist, Petra; Alm, Erik; Lilje, Berit; Westh, Henrik; Stegger, Marc; Hasman, Henrik

2017-08-01

To describe the changing epidemiology of vancomycin-resistant Enterococcus faecium and Enterococcus faecalis in clinical samples in Denmark 2005-15 according to species and van type, and, furthermore, to investigate the genetic relatedness of the clinical E. faecium isolates from 2015. During 2005-14, all clinical VRE isolates were tested for the presence of vanA/B/C genes by PCR. In 2015, all clinical VRE isolates were whole-genome sequenced. From the WGS data, the presence of van genes and MLST STs were extracted in silico . Core-genome MLST (cgMLST) analysis was performed for the vancomycin-resistant E. faecium isolates. During 2005-15, 1043 vanA E. faecium , 25 vanB E. faecium , 4 vanA E. faecalis and 28 vanB E. faecalis were detected. The number of VRE was <50 isolates/year until 2012 to > 200 isolates/year in 2013-15. In 2015, 368 vanA E. faecium and 1 vanB E. faecium were detected along with 1 vanA E. faecalis and 1 vanB E. faecalis . cgMLST subdivided the 368 vanA E. faecium isolates into 33 cluster types (CTs), whereas the vanB E. faecium isolate belonged to a different CT. ST203-CT859 was most prevalent (51%), followed by ST80-CT14 (22%), ST117-CT24 (6%), ST80-CT866 (4%) and ST80-CT860 (2%). Comparison with the cgMLST.org database, previous studies and personal communications with neighbouring countries revealed that the novel cluster ST203-CT859 emerged in December 2014 and spread to the south of Sweden and the Faroe Islands during 2015. VRE increased in Denmark during 2005-15 due to the emergence of several vanA E. faecium clones. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Vancomycin-resistance phenotypes, vancomycin-resistance genes, and resistance to antibiotics of enterococci isolated from food of animal origin.

PubMed

Gousia, Panagiota; Economou, Vangelis; Bozidis, Petros; Papadopoulou, Chrissanthy

2015-03-01

In the present study, 500 raw beef, pork, and chicken meat samples and 100 pooled egg samples were analyzed for the presence of vancomycin-resistant enterococci, vancomycin-resistance phenotypes, and resistance genes. Of 141 isolates of enterococci, 88 strains of Enterococcus faecium and 53 strains of E. faecalis were identified. The most prevalent species was E. faecium. Resistance to ampicillin (n = 93, 66%), ciprofloxacin (n = 74, 52.5%), erythromycin (n = 73, 51.8%), penicillin (n = 59, 41.8%) and tetracycline (n = 52, 36.9%) was observed, while 53.2% (n = 75) of the isolates were multiresistant and 15.6% (n = 22) were susceptible to all antibiotics. Resistance to vancomycin was exhibited in 34.1% (n = 30) of the E. faecium isolates (n = 88) and 1.9% (n = 1) of the E. faecalis isolates (n = 53) using the disc-diffusion test and the E-test. All isolates were tested for vanA and vanB using real-time polymerase chain reaction (PCR) and multiplex PCR, and for vanC, vanD, vanE, vanG genes using multiplex PCR only. Among E. faecalis isolates, no resistance genes were identified. Among the E. faecium isolates, 28 carried the vanA gene when tested by multiplex PCR and 29 when tested with real-time PCR. No isolate carrying the vanC, vanD, vanE, or vanG genes was identified. Melting-curve analysis of the positive real-time PCR E. faecium isolates showed that 22 isolates carried the vanA gene only, 2 isolates the vanB2,3 genes only, and seven isolates carried both the vanA and vanB2,3 genes. Enterococci should be considered a significant zoonotic pathogen and a possible reservoir of genes encoding resistance potentially transferred to other bacterial species.

Wind and Current Forces Acting on Canadian Forces Ships During Tug Operations

DTIC Science & Technology

2002-11-01

McTaggart and Sav- age [1] describe model tests conducted on a generic frigate model to determine wind forces influencing ship capsize. Van Manen and van ...Fn will be 0.06. Based on data presented by van Manen and van Oossanen [2], the fric- tional resistance coefficient will be approximately 0.002 and...Conference on Stability of Ships and Ocean Vehicles (Melbourne, Florida, 1994). 2. J.D. van Manen and P. van Oossanen, Principles of Naval Architecture, Volume

Synergistic Interactions of Vancomycin with Different Antibiotics against Escherichia coli: Trimethoprim and Nitrofurantoin Display Strong Synergies with Vancomycin against Wild-Type E. coli

PubMed Central

Zhou, Alice; Kang, Tina Manzhu; Yuan, Jessica; Beppler, Casey; Nguyen, Caroline; Mao, Zhiyuan; Nguyen, Minh Quan

2014-01-01

Gram-negative bacteria are normally resistant to the antibiotic vancomycin (VAN), which cannot significantly penetrate the outer membrane. We used Escherichia coli mutants that are partially sensitive to VAN to study synergies between VAN and 10 other antibiotics representing six different functional categories. We detected strong synergies with VAN and nitrofurantoin (NTR) and with VAN and trimethoprim (TMP) and moderate synergies with other drugs, such as aminoglycosides. These synergies are powerful enough to show the activity of VAN against wild-type E. coli at concentrations of VAN as low as 6.25 μg/ml. This suggests that a very small percentage of exogenous VAN does enter E. coli but normally has insignificant effects on growth inhibition or cell killing. We used the results of pairwise interactions with VAN and the other 10 antibiotics tested to place VAN into a functional category of its own, as previously defined by Yeh et al. (P. Yeh, A. I. Tschumi, and R. Kishony, Nat Genet 28:489–494, 2006, http://dx.doi.org/10.1038/ng1755). PMID:25348521

Glucagon-like peptide-1 regulates brown adipose tissue thermogenesis via the gut-brain axis in rats.

PubMed

Krieger, Jean-Philippe; Santos da Conceição, Ellen Paula; Sanchez-Watts, Graciela; Arnold, Myrtha; Pettersen, Klaus G; Mohammed, Mazher; Modica, Salvatore; Lossel, Pius; Morrison, Shaun F; Madden, Christopher J; Watts, Alan G; Langhans, Wolfgang; Lee, Shin J

2018-05-30

Endogenous intestinal glucagon-like peptide-1 (GLP-1) controls satiation and glucose metabolism via vagal afferent neurons (VAN). Recently, VAN have received increasing attention for their role in brown adipose tissue (BAT) thermogenesis. It is however unclear whether VAN GLP-1 receptor (GLP-1R) signaling affects BAT thermogenesis and energy expenditure (EE), and whether this VAN mechanism contributes to energy balance. First, we tested the effect of the GLP-1R agonist Exendin-4 (Ex4, 0.3 μg/kg IP) on EE and BAT thermogenesis, and whether these effects require VAN GLP-1R signaling, using a rat model with a selective Glp1r knockdown (kd) in VAN. Second, we examined the role of VAN GLP-1R in energy balance during chronic high-fat diet (HFD) feeding in VAN Glp1r kd rats. Lastly, we used viral transsynaptic tracers to identify the possible neuronal substrates of such a gut-BAT interaction. VAN Glp1r kd attenuated the acute suppressive effects of Ex4 on EE and BAT thermogenesis. Consistent with this finding, the VAN Glp1r kd increased EE and BAT activity, diminished body weight gain, and improved insulin sensitivity compared to HFD-fed controls. Anterograde transsynaptic viral tracing of VAN infected major hypothalamic and hindbrain areas involved in BAT sympathetic regulation. Moreover, retrograde tracing from BAT combined with laser capture microdissection revealed that a population of VAN expressing Glp1r is synaptically connected to the BAT. Our findings reveal a novel role of VAN GLP-1R signaling in the regulation of EE and BAT thermogenesis, and imply that through this gut-brain-BAT connection intestinal GLP-1 plays a role in HFD-induced metabolic syndrome.

Evaluatie Kennistechnologische Ondersteuning bij Diagnose van SEWACO systemen (Projectmanagementplan) (Evaluation of Knowledge Technological Support for Diagnosis of SEWACO Systems (Project Management Plan)

DTIC Science & Technology

1991-08-01

diagnos van SE WACO systmnen/ AD-A245 424111 1fl1,l Niets uit deze uitgave mag warden vermenigvuldligd en/of oPenbaar gemaakt door middel van druk...fotakopie. microfilm of op welks andere whlze dan ook, zonder voorafgaande toeslemming van TNO. Hot ter inzage geven van het TNO-rapport aan direct...belanghebbenden is tegestaan. HYP. vanl OC dt Indian dit rapport in opdracht ward uitgebracht, wordt voor de, rechten en verpiichtingen van opdrachtgever en

The phosphotransferase VanU represses expression of four qrr genes antagonizing VanO-mediated quorum-sensing regulation in Vibrio anguillarum

PubMed Central

Weber, Barbara; Lindell, Kristoffer; El Qaidi, Samir; Hjerde, Erik; Willassen, Nils-Peder

2011-01-01

Vibrio anguillarum utilizes quorum sensing to regulate stress responses required for survival in the aquatic environment. Like other Vibrio species, V. anguillarum contains the gene qrr1, which encodes the ancestral quorum regulatory RNA Qrr1, and phosphorelay quorum-sensing systems that modulate the expression of small regulatory RNAs (sRNAs) that destabilize mRNA encoding the transcriptional regulator VanT. In this study, three additional Qrr sRNAs were identified. All four sRNAs were positively regulated by σ54 and the σ54-dependent response regulator VanO, and showed a redundant activity. The Qrr sRNAs, together with the RNA chaperone Hfq, destabilized vanT mRNA and modulated expression of VanT-regulated genes. Unexpectedly, expression of all four qrr genes peaked at high cell density, and exogenously added N-acylhomoserine lactone molecules induced expression of the qrr genes at low cell density. The phosphotransferase VanU, which phosphorylates and activates VanO, repressed expression of the Qrr sRNAs and stabilized vanT mRNA. A model is presented proposing that VanU acts as a branch point, aiding cross-regulation between two independent phosphorelay systems that activate or repress expression of the Qrr sRNAs, giving flexibility and precision in modulating VanT expression and inducing a quorum-sensing response to stresses found in a constantly changing aquatic environment. PMID:21948044

The phosphotransferase VanU represses expression of four qrr genes antagonizing VanO-mediated quorum-sensing regulation in Vibrio anguillarum.

PubMed

Weber, Barbara; Lindell, Kristoffer; El Qaidi, Samir; Hjerde, Erik; Willassen, Nils-Peder; Milton, Debra L

2011-12-01

Vibrio anguillarum utilizes quorum sensing to regulate stress responses required for survival in the aquatic environment. Like other Vibrio species, V. anguillarum contains the gene qrr1, which encodes the ancestral quorum regulatory RNA Qrr1, and phosphorelay quorum-sensing systems that modulate the expression of small regulatory RNAs (sRNAs) that destabilize mRNA encoding the transcriptional regulator VanT. In this study, three additional Qrr sRNAs were identified. All four sRNAs were positively regulated by σ(54) and the σ(54)-dependent response regulator VanO, and showed a redundant activity. The Qrr sRNAs, together with the RNA chaperone Hfq, destabilized vanT mRNA and modulated expression of VanT-regulated genes. Unexpectedly, expression of all four qrr genes peaked at high cell density, and exogenously added N-acylhomoserine lactone molecules induced expression of the qrr genes at low cell density. The phosphotransferase VanU, which phosphorylates and activates VanO, repressed expression of the Qrr sRNAs and stabilized vanT mRNA. A model is presented proposing that VanU acts as a branch point, aiding cross-regulation between two independent phosphorelay systems that activate or repress expression of the Qrr sRNAs, giving flexibility and precision in modulating VanT expression and inducing a quorum-sensing response to stresses found in a constantly changing aquatic environment.

Implementation of Two-Component Time-Dependent Density Functional Theory in TURBOMOLE.

PubMed

Kühn, Michael; Weigend, Florian

2013-12-10

We report the efficient implementation of a two-component time-dependent density functional theory proposed by Wang et al. (Wang, F.; Ziegler, T.; van Lenthe, E.; van Gisbergen, S.; Baerends, E. J. J. Chem. Phys. 2005, 122, 204103) that accounts for spin-orbit effects on excitations of closed-shell systems by employing a noncollinear exchange-correlation kernel. In contrast to the aforementioned implementation, our method is based on two-component effective core potentials as well as Gaussian-type basis functions. It is implemented in the TURBOMOLE program suite for functionals of the local density approximation and the generalized gradient approximation. Accuracy is assessed by comparison of two-component vertical excitation energies of heavy atoms and ions (Cd, Hg, Au(+)) and small molecules (I2, TlH) to other two- and four-component approaches. Efficiency is demonstrated by calculating the electronic spectrum of Au20.

Review of Stantonia Ashmead (Hymenoptera, Braconidae, Orgilinae) from Vietnam, China, Japan, and Russia, with descriptions of six new species

PubMed Central

van Achterberg, Cornelis; Long, Khuat Dang; Chen, Xue-xin

2017-01-01

Abstract The genus Stantonia Ashmead, 1904 (Hymenoptera, Braconidae, Orgilinae) is reviewed for Vietnam, China, Japan, and Russia. Six new species of the genus Stantonia are described and illustrated: Stantonia brevicaudata van Achterberg, sp. n., S. dickyyui van Achterberg & Long, sp. n., S. granulata Long & van Achterberg, sp. n., S. robustifemur van Achterberg & Long, sp. n., S. stilpnosoma Long & van Achterberg, sp. n., and S. vietnamica van Achterberg, sp. n. A new subgenus (Planitonia subg. n.: type species Stantonia robustifemur van Achterberg & Long, sp. n.) is proposed for the species with a flat clypeus and face, and reduced vein r-m of the fore wing. Three species are newly recorded from Vietnam: Stantonia gracilis van Achterberg, 1987, S. sumatrana Enderlein, 1908, and S. tianmushana Chen, He & Ma, 2004. A key to species of Stantonia from Vietnam, China, Russia, and Japan is provided. PMID:29362527

Quantitative Characterization of Molecular Similarity Spaces: Tools for Computational Toxicology

DTIC Science & Technology

2000-01-20

numbers for hydrogen-filled molecular structure, hydrogen-suppressed molecular structure, and van der Waals volume. Van der Waals...relative covalent radii Geometrical Vw van der Waals volume 3DW 3-D Wiener number for the hydrogen-suppressed geometric distance matrix...molecular structure, and van der Waals volume. Van der Waals volume, Vw (Bondi 1964). was calculated using Sybyl 6.1 from Tripos As- sociates. Inc

Physical Protection: the State of the Art

DTIC Science & Technology

2005-02-01

fundamentele mechanisme van adsorptie van water beschrijft; dit is ingewikkeld en kost veel tijd ; een tweede benadering is het opstellen van een eenvoudig...gasscheidingsmethoden, bij voorkeur regeneratief, zijn zeer wenselijk vanwege de logistieke voordelen en de gegarandeerde langere operatie tijd . P(T)SA is meer...in de loop van de tijd ) met vrij simpele middelen en technieken sterk worden verbeterd. Deze technieken, zoals micro-encapsulatie en toevoeging van

Thickened boundary layer theory for air film drag reduction on a van body surface

NASA Astrophysics Data System (ADS)

Xie, Xiaopeng; Cao, Lifeng; Huang, Heng

2018-05-01

To elucidate drag reduction mechanism on a van body surface under air film condition, a thickened boundary layer theory was proposed and a frictional resistance calculation model of the van body surface was established. The frictional resistance on the van body surface was calculated with different parameters of air film thickness. In addition, the frictional resistance of the van body surface under the air film condition was analyzed by computational fluid dynamics (CFD) simulation and different air film states that influenced the friction resistance on the van body surface were discussed. As supported by the CFD simulation results, the thickened boundary layer theory may provide reference for practical application of air film drag reduction on a van body surface.

Assessing Alternative Breaks: Moving beyond Sleeping on Floors and Pass-the-Candle Reflection

ERIC Educational Resources Information Center

Porter, Melody C.

2011-01-01

Alternative breaks (ABs) often bring a smattering of images to mind: college students in matching T-shirts, cramped vans, well-used work gloves, physical labor, and, perhaps, way too much peanut butter. All of these images are at least in part accurate for the AB program at the College of William and Mary. Add to them a strong sense that sending…

Peterson's Top Colleges for Science: A Guide to Leading Four-Year Programs in the Biological, Chemical, Geological, Mathematical, and Physical Sciences.

ERIC Educational Resources Information Center

Davis-Van Atta, David, Ed.

This guide, published for the first time, provides prospective college students detailed information on 190 United States colleges and universities identified as having very strong track records in the sciences and mathematics. Following a description of how institutions were identified for inclusion by David Davis-Van Atta, and a discussion on…

Calculating the return on investment of mobile healthcare.

PubMed

Oriol, Nancy E; Cote, Paul J; Vavasis, Anthony P; Bennet, Jennifer; Delorenzo, Darien; Blanc, Philip; Kohane, Isaac

2009-06-02

Mobile health clinics provide an alternative portal into the healthcare system for the medically disenfranchised, that is, people who are underinsured, uninsured or who are otherwise outside of mainstream healthcare due to issues of trust, language, immigration status or simply location. Mobile health clinics as providers of last resort are an essential component of the healthcare safety net providing prevention, screening, and appropriate triage into mainstream services. Despite the face value of providing services to underserved populations, a focused analysis of the relative value of the mobile health clinic model has not been elucidated. The question that the return on investment algorithm has been designed to answer is: can the value of the services provided by mobile health programs be quantified in terms of quality adjusted life years saved and estimated emergency department expenditures avoided? Using a sample mobile health clinic and published research that quantifies health outcomes, we developed and tested an algorithm to calculate the return on investment of a typical broad-service mobile health clinic: the relative value of mobile health clinic services = annual projected emergency department costs avoided + value of potential life years saved from the services provided. Return on investment ratio = the relative value of the mobile health clinic services/annual cost to run the mobile health clinic. Based on service data provided by The Family Van for 2008 we calculated the annual cost savings from preventing emergency room visits, $3,125,668 plus the relative value of providing 7 of the top 25 priority prevention services during the same period, US$17,780,000 for a total annual value of $20,339,968. Given that the annual cost to run the program was $567,700, the calculated return on investment of The Family Van was 36:1. By using published data that quantify the value of prevention practices and the value of preventing unnecessary use of emergency departments, an empirical method was developed to determine the value of a typical mobile health clinic. The Family Van, a mobile health clinic that has been serving the medically disenfranchised of Boston for 16 years, was evaluated accordingly and found to have return on investment of $36 for every $1 invested in the program.

76 FR 57105 - Greenhouse Gas Emissions Standards and Fuel Efficiency Standards for Medium- and Heavy-Duty...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-15

...EPA and NHTSA, on behalf of the Department of Transportation, are each finalizing rules to establish a comprehensive Heavy-Duty National Program that will reduce greenhouse gas emissions and fuel consumption for on-road heavy-duty vehicles, responding to the President's directive on May 21, 2010, to take coordinated steps to produce a new generation of clean vehicles. NHTSA's final fuel consumption standards and EPA's final carbon dioxide (CO2) emissions standards are tailored to each of three regulatory categories of heavy-duty vehicles: Combination Tractors; Heavy-duty Pickup Trucks and Vans; and Vocational Vehicles. The rules include separate standards for the engines that power combination tractors and vocational vehicles. Certain rules are exclusive to the EPA program. These include EPA's final hydrofluorocarbon standards to control leakage from air conditioning systems in combination tractors, and pickup trucks and vans. These also include EPA's final nitrous oxide (N2O) and methane (CH4) emissions standards that apply to all heavy- duty engines, pickup trucks and vans. EPA's final greenhouse gas emission standards under the Clean Air Act will begin with model year 2014. NHTSA's final fuel consumption standards under the Energy Independence and Security Act of 2007 will be voluntary in model years 2014 and 2015, becoming mandatory with model year 2016 for most regulatory categories. Commercial trailers are not regulated in this phase of the Heavy-Duty National Program. The agencies estimate that the combined standards will reduce CO2 emissions by approximately 270 million metric tons and save 530 million barrels of oil over the life of vehicles sold during the 2014 through 2018 model years, providing over $7 billion in net societal benefits, and $49 billion in net societal benefits when private fuel savings are considered. EPA is also finalizing provisions allowing light-duty vehicle manufacturers to use CO2 credits to meet the light-duty vehicle N2O and CH4 standards, technical amendments to the fuel economy provisions for light-duty vehicles, and a technical amendment to the criteria pollutant emissions requirements for certain switch locomotives.

AUC/MIC Pharmacodynamic Target Is Not a Good Predictor of Vancomycin Efficacy in Methicillin-Resistant Staphylococcus aureus Experimental Endocarditis

PubMed Central

Castañeda, Ximena; García-de-la-Mària, Cristina; Gasch, Oriol; Pericas, Juan M.; Armero, Yolanda; Soy, Dolors; García-González, Javier; Falces, Carlos; Ninot, Salvador; Almela, Manel; Ambrosioni, Juan; Quintana, Eduardo; Vidal, Barbara; Fuster, David; Llopis, Jaume; Soto, Sara; Moreno, Asuncion; Marco, Francesc

2017-01-01

ABSTRACT The aim of this in vivo study was to compare the efficacy of vancomycin at standard doses (VAN-SD) to that of VAN at adjusted doses (VAN-AD) in achieving a VAN area under the curve/MIC ratio (AUC/MIC) of ≥400 against three methicillin-resistant Staphylococcus aureus (MRSA) strains with different microdilution VAN MICs in an experimental endocarditis model. The valve vegetation bacterial counts after 48 h of VAN therapy were compared, and no differences were observed between the two treatment groups for any of the three strains tested. Overall, for VAN-SD and VAN-AD, the rates of sterile vegetations were 15/45 (33.3%) and 21/49 (42.8%) (P = 0.343), while the medians (interquartile ranges [IQRs]) for log10 CFU/g of vegetation were 2 (0 to 6.9) and 2 (0 to 4.5) (P = 0.384), respectively. In conclusion, this VAN AUC/MIC pharmacodynamic target was not a good predictor of vancomycin efficacy in MRSA experimental endocarditis. PMID:28373187

AUC/MIC Pharmacodynamic Target Is Not a Good Predictor of Vancomycin Efficacy in Methicillin-Resistant Staphylococcus aureus Experimental Endocarditis.

PubMed

Castañeda, Ximena; García-de-la-Mària, Cristina; Gasch, Oriol; Pericas, Juan M; Armero, Yolanda; Soy, Dolors; García-González, Javier; Falces, Carlos; Ninot, Salvador; Almela, Manel; Ambrosioni, Juan; Quintana, Eduardo; Vidal, Barbara; Fuster, David; Llopis, Jaume; Soto, Sara; Moreno, Asuncion; Marco, Francesc; Miró, Jose M

2017-06-01

The aim of this in vivo study was to compare the efficacy of vancomycin at standard doses (VAN-SD) to that of VAN at adjusted doses (VAN-AD) in achieving a VAN area under the curve/MIC ratio (AUC/MIC) of ≥400 against three methicillin-resistant Staphylococcus aureus (MRSA) strains with different microdilution VAN MICs in an experimental endocarditis model. The valve vegetation bacterial counts after 48 h of VAN therapy were compared, and no differences were observed between the two treatment groups for any of the three strains tested. Overall, for VAN-SD and VAN-AD, the rates of sterile vegetations were 15/45 (33.3%) and 21/49 (42.8%) ( P = 0.343), while the medians (interquartile ranges [IQRs]) for log 10 CFU/g of vegetation were 2 (0 to 6.9) and 2 (0 to 4.5) ( P = 0.384), respectively. In conclusion, this VAN AUC/MIC pharmacodynamic target was not a good predictor of vancomycin efficacy in MRSA experimental endocarditis. Copyright © 2017 American Society for Microbiology.

Transient aerodynamic characteristics of vans during the accelerated overtaking process

NASA Astrophysics Data System (ADS)

Liu, Li-ning; Wang, Xing-shen; Du, Guang-sheng; Liu, Zheng-gang; Lei, Li

2018-04-01

This paper studies the influence of the accelerated overtaking process on the vehicles' transient aerodynamic characteristics, through 3-D numerical simulations with dynamic meshes and sliding interface technique. Numerical accuracy is verified by experimental results. The aerodynamic characteristics of vehicles in the uniform overtaking process and the accelerated overtaking process are compared. It is shown that the speed variation of the overtaking van would influence the aerodynamic characteristics of the two vans, with greater influence on the overtaken van than on the overtaking van. The simulations of three different accelerated overtaking processes show that the greater the acceleration of the overtaking van, the larger the aerodynamic coefficients of the overtaken van. When the acceleration of the overtaking van increases by 1 m/s2, the maximum drag force, side force and yawing moment coefficients of the overtaken van all increase by more than 6%, to seriously affect the power performance and the stability of the vehicles. The analysis of the pressure fields under different accelerated conditions reveals the cause of variations of the aerodynamic characteristics of vehicles.

Socialization Practices, Job Satisfaction and Commitment,

DTIC Science & Technology

1983-01-01

organizational entry practice? Neither researchers nor practitioners have directly addressed this issue. Van Manen ( Van Hasnen, 1978) identified seven dimensions...TR-2 John Van Maanen, "Some Thoughts (and Afterthoughts) on Context, Interpretation, and Organization Theory" February, 1982. TR1-3 John Van Maanen...Contradictions in Technical Careers" March, 1982; Working Paper 1281-82. TR-5 John Van Maanen & Deborah Kolb. "The Professional Apprentice: Observations on Fie1

Inventarisatie telematica-ontwikkelingen Natco (Inventory Telematics Developments Natco)

DTIC Science & Technology

1998-05-01

telefonie, die binnen afzienbare tijd een bereikbaarheid over nagenoeg de gehele wereldbol kan garanderen. Ook hier is de koppeling van netwerken van...PCS is ’de mogelijkheid voor een gebruiker te communiceren in elke gewenste vorm, op elke tijd , op elke plaats en in verschillende rollen...wat betreft plaats, tijd en tempo van het leren, kan worden gerealiseerd. De toepassing van teleleren kan leiden tot een verbetering van de interne

Evaporation from Sand

DTIC Science & Technology

1992-04-01

Instituuts Advies R2ad PML Prof. dr. U.A.Th. Brinkanl~ 36. Direactur van het Medisch Biologisch Laboratorium TNO Prof.Dr. W.R.F. Notten 37. Directeur...Grootsdialige Rampenbestrijdcing Ministerie van Binnenlandsc Zaken Drs. H. Evers 9. Adviseur van het Prins Maurits Laboratorium TWO Prot. Dr. J.M. van...Rossum, 10. Adyisew, van het Prins Maurits Laboratorium TWO Chernisdie Research Prof.Dr. G. Dijkstra 11. H~ur. NBC DMKIJOMAT/KIO Ir. AAM. Slagveer 12

Mobile Telemetry Van Remote Control Upgrade

DTIC Science & Technology

2012-05-17

Advantages of Remote Control System Upgrade • Summary Overview • Remote control of Telemetry Mobile Ground Support ( TMGS ) Van proposed to allow...NWC) personnel provided valuable data for full-function remote control of telemetry tracking vans Background • TMGS Vans support Flight Test...control capability from main TM site at Building 5790 currently allows support via TMGS Van at nearby C- 15 Site, Plant 42 in Palmdale, and as far

Synthetic Minor NSR Permit: Van Hook Crude Terminal, LLC - Van Hook Crude Terminal/Rail Loading Facility

EPA Pesticide Factsheets

This page contains the current effective synthetic minor NSR permit for the Van Hook Crude Terminal, LLC, Van Hook Crude Terminal/Rail Loading Facility, located on the Fort Berthold Indian Reservation in Mountrail County, ND.

Presence of the resistance genes vanC1 and pbp5 in phenotypically vancomycin and ampicillin susceptible Enterococcus faecalis.

PubMed

Schwaiger, Karin; Bauer, Johann; Hörmansdorfer, Stefan; Mölle, Gabriele; Preikschat, Petra; Kämpf, Peter; Bauer-Unkauf, Ilse; Bischoff, Meike; Hölzel, Christina

2012-08-01

Ampicillin and vancomycin are important antibiotics for the therapy of Enterococcus faecalis infections. The ampicillin resistance gene pbp5 is intrinsic in Enterococcus faecium. The vanC1 gene confers resistance to vancomycin and serves as a species marker for Enterococcus gallinarum. Both genes are chromosomally located. Resistance to ampicillin and vancomycin was determined in 484 E. faecalis of human and porcine origin by microdilution. Since E. faecalis are highly skilled to acquire resistance genes, all strains were investigated for the presence of pbp5 (and, in positive strains, for the penicillin-binding protein synthesis repressor gene psr) and vanC1 (and, in positive strains, for vanXYc and vanT) by using polymerase chain reaction (PCR). One porcine and one human isolate were phenotypically resistant to ampicillin; no strain was vancomycin resistant. Four E. faecalis (3/1 of porcine/human origin) carried pbp5 (MIC=1 mg/L), and four porcine strains were vanC1 positive (minimum inhibitory concentration [MIC]=1 mg/L). Real-time reverse transcriptase (RT)-PCR revealed that the genes were not expressed. The psr gene was absent in the four pbp5-positive strains; the vanXYc gene was absent in the four vanC1-positive strains. However, vanT of the vanC gene cluster was detected in two vanC1-positive strains. To our knowledge, this is the first report on the presence of pbp5, identical with the "E. faecium pbp5 gene," and of vanC1/vanT in E. faecalis. Even if resistance is not expressed in these strains, this study shows that E. faecalis have a strong ability to acquire resistance genes-and potentially to spread them to other bacteria. Therefore, close monitoring of this species should be continued.

Dynamical importance of van der Waals saddle and excited potential surface in C(1D)+D2 complex-forming reaction

PubMed Central

Shen, Zhitao; Ma, Haitao; Zhang, Chunfang; Fu, Mingkai; Wu, Yanan; Bian, Wensheng; Cao, Jianwei

2017-01-01

Encouraged by recent advances in revealing significant effects of van der Waals wells on reaction dynamics, many people assume that van der Waals wells are inevitable in chemical reactions. Here we find that the weak long-range forces cause van der Waals saddles in the prototypical C(1D)+D2 complex-forming reaction that have very different dynamical effects from van der Waals wells at low collision energies. Accurate quantum dynamics calculations on our highly accurate ab initio potential energy surfaces with van der Waals saddles yield cross-sections in close agreement with crossed-beam experiments, whereas the same calculations on an earlier surface with van der Waals wells produce much smaller cross-sections at low energies. Further trajectory calculations reveal that the van der Waals saddle leads to a torsion then sideways insertion reaction mechanism, whereas the well suppresses reactivity. Quantum diffraction oscillations and sharp resonances are also predicted based on our ground- and excited-state potential energy surfaces. PMID:28094253

International Hydrogenase Conference (7th) Held at the University of Reading on August 24th to 29th 2004.

DTIC Science & Technology

2004-08-19

Johannes Hackstein [ PB GIO rNovel Fe-hydrogenases from the rumen ciliate metagenome . :12.50 :114.00 -1 Lunch [ 114.00 1 7.00 1 Poster Session 2...d.r.o’ g’.e n-.a-.s.e..s from the rumnen ciliate metagenome . p36 Severing, E., Boxma, B., van Alen, T.A., Ricard, G., van Hoek, A.H.A.M., Moon-van...hydrogenases from the rumen ciliate metagenome . Severing, E.’, Boxma, B.1, van Alen, T.A.’, Ricard, G.z, van Hoek, A.H.A.M.’, Moon-van der Staay, S.Y

Genetics Home Reference: bare lymphocyte syndrome type II

MedlinePlus

... 6. Citation on PubMed Gobin SJ, Peijnenburg A, van Eggermond M, van Zutphen M, van den Berg R, van den Elsen PJ. The RFX complex is crucial ... D, Szöllosi J, Jenei A. Bare lymphocyte syndrome: an opportunity to discover our immune system. Immunol Lett. ...

Measurements of Propeller-Induced Unsteady Surface Force and Pressures

DTIC Science & Technology

1986-12-01

investigations using foreshortened hull models in the determination of cavitating propeller-induced pressure pulses include van Manen , 46 Huse,47 van Oossanen...Nov 1974). 46. van Manen , J.D., "The Effect of Cavitation on the Interaction Between Propeller and Ship’s Hull, "International Shipbuilding Progress...and van der Kooij,48 and van der Kooij and Jonk. 49 Examples of more recent publications that have either made use of results from dummy model tests or

Combination Vancomycin/Cefazolin (VAN/CFZ) for Methicillin-Resistant Staphylococcus aureus (MRSA) Bloodstream Infections (BSI)

PubMed Central

Trinh, Trang D; Zasowski, Evan J; Lagnf, Abdalhamid M; Bhatia, Sahil; Dhar, Sorabh; Mynatt, Ryan; Pogue, Jason M; Rybak, Michael J

2017-01-01

Abstract Background VAN remains the standard for MRSA BSI but has been associated with treatment failures and resulted in prolonged BSI durations and recurrences. In vitro studies of VAN/CFZ against MRSA demonstrated synergy and prevention of VAN resistance. However, clinical use of VAN/CFZ has not been reported. The objective of this study was to compare patient outcomes treated with VAN/CFZ vs. VAN for MRSA BSI. Methods This was a retrospective, cohort, comparative-effectiveness study of hospitalized adults ≥18y with ≥1 MRSA blood culture and received VAN/CFZ combination for ≥24h or VAN alone initiated within 72h of index infection between 1/1/08 and 5/1/17. Patients who received >24h β-lactams other than CFZ, MRSA-active antibiotics other than VAN, with polymicrobial BSI, or had a second MRSA BSI episode during the study period were excluded. The primary composite failure outcome included: 30d mortality, MRSA BSI ≥7d, and 60d recurrence. Demographics were compared by Χ2, Fisher’s exact, Student’s t, or Mann–Whitney U tests. Multivariable regression models compared outcomes between the two treatment groups. Covariates with p-values ≤0.2 in bivariate analyses were included in the model. Results A total of 101 patients were included (CFZ/VAN = 41, VAN = 60). Demographics were similar except VAN patients were older (mean (±SD) age 58 (±14) v. 51 (±18) y, P = 0.04), had higher median (IQR) Charlson Comorbidity Index (3 (2-5) v. 1 (0–4), P < 0.01), APACHE II scores (13 (8-18) v. 11 (8-18), P = 0.2), and more endocarditis BSI source (37% v. 20%, P = 0.06). After accounting for BSI source, VAN/CFZ (adjusted odds ratio [aOR], 95% confidence intervals [CI], 0.33, 0.13-0.83) and low APACHE II scores (aOR 1.07, 95% CI 1–1.15) were independently associated with fewer failures. Bivariate outcomes are in table below: Variable, n (%) VAN/CFZ VAN P value Composite failure 10 (24) 31 (52) 0.006 30d mortality 3 (7.3) 5 (8.3) 1 BSI ≥7d 6 (15) 21 (35) 0.023 60d recurrence 3 (7.3) 9 (15) 0.351 Failure switch 1 (2.4) 10 (17) 0.026 Conclusion In this cohort of MRSA BSI, patients treated with VAN/CFZ experienced fewer failures than with VAN alone, with shorter BSI durations. Additional studies are needed to confirm the role of VAN/CFZ combination treatment for MRSA BSI. Disclosures J. M. Pogue, Achaogen, Inc.: Consultant, Consulting fee. M. J. Rybak, Allergen: Scientific Advisor, Consulting fee.

Learning from Profiles of the Special Needs Gifted

ERIC Educational Resources Information Center

Swanson, Julie Dingle; Van Tassel-Baska, Joyce; Feng, Annie; Chandler, Kimberley

2007-01-01

Through a longitudinal study focused on identification policy that is inclusive of underrepresented gifted students (Van Tassel-Baska & Feng, 2003; Van Tassel-Baska, Feng, & deBrux, under review; Van Tassel-Baska, Feng, & Evans, in press; Van Tassel-Baska, Johnson, & Avery, 2002), a team of researchers developed case studies of special needs…

Representation of Research Paradigms as a Function of Familiarity with Research Domains

DTIC Science & Technology

1992-07-01

van de paradigma’s te kunnen vaststellen. Keuze van het Juiste paradigma werd bepaald door proefpersonen te vragen de betreffende zin te classificeren...als afkomstig van een bepaaid type onderzoek. De innoud van het paradigma werd bepaald door proefpersonen te, vragen zoveel kenmerken voor bet

Additional Value from Road Mapping in Defense Policy Making (meerwaarde van roadmapping bij beleidsontwikkeling van de koninklijke landmacht)

DTIC Science & Technology

2006-05-01

van zogonaamde strategische reserves tot bijvaarbeeld lakaal boschikbare gevechtscapacitoit. 9 11 Joint. Do Nederlandse krijgsmacht ontwikkelt zich tot...8 2 W erkwijze van de KL tot nu toe ............................................................................... 9 2.1 O...ntwikkeling visiedocurnent ....................................................................................... 9 2.2 Opzet beleid- en deelstudies

Individualized Biomathematical Modeling of Fatigue and Performance

DTIC Science & Technology

2008-05-29

NUMBER Fatigue and Performance 5b. GRANT NUMBER FA9550-06-1-0055 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Hans P.A. Van Dongen, Ph.D...5d. PROJECT NUMBER (Principal Investigator) 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES...Sleep and Performance Research Center 8. PERFORMING ORGANIZATION REPORT NUMBER Washington State University, Spokane P.O. Box 1495 Spokane, WA

National Program for Inspection of Non-Federal Dams. Fernwood Lake Dam (MA 00184) Massachusetts Coastal Basin, Gloucester, Massachusetts. Phase I Inspection Report.

DTIC Science & Technology

1979-04-01

top of the concrete for dowels. September 4, 1929. At 7:00 A. K. five men began concreting. Mr. - vans was at the work this morning. A thin mixture was...not carried below the surfatc jjhch iapytially rock fill and partially earth, pparently. he walls nay not prove very per- manen but they af rd a good

Naval Air Systems Command Mobile Facility Program

DTIC Science & Technology

2009-11-03

Julie Trossbach 301-757-3073 Database Manager – Emi McCutcheon 301-757- 8347 BFM – Michelle Moorman 301-757-8328 Comptroller Analyst – Kathy...Jamie McDonald (757) 444-1428 NAVAIR Mobile Facilities MFTool/Database AIR 6.7.6.2 Emi McCutcheon (301) 757-8347 NAVAIR Mobile Facilities Logistics...requirement for mobile trailer -type vans for peculiar jet aircraft maintenance – Needed dust free, temperature & humidity-controlled maintenance

Initieole Behoeflebepaling GOLMen voor Opleiding Waarnemer in Fennek VWPN (Initial Training Needs Analysis for the RNLA Observer Equipped With Fennek VWRN)

DTIC Science & Technology

2006-08-01

Auteur (s) drs. A.S. Helsdingen Programmanummer Projectnummer 032.10190 Rubnicering rapport Ongerubriceerd Program ma planning Projectplanning Start 20-4...voorbereiding). Tabel 5 Taxonomie van type vaardigheden. Theorie Achtergrondkennis over de missies en do taken, randvoorwaarden, regels en procedures voor...manoeuvrelnablj Optreden achtergebied Targetting Theorie (systeemkennis) Uitvoeren ECM Waarnemingspost betrekken en in stand houden Uitbouwen BAA kop

NATCON Papers 1998 = Les Actes du CONAT [1998]. Papers Presented at the Annual Meeting of the National Consultation on Career Development (NATCON) (24th, Ottawa, Ontario, Canada, January 26-28, 1998).

ERIC Educational Resources Information Center

National Consultation on Career Development (NATCON), Toronto (Ontario).

Papers published in NATCON 1998 are: (1) "A Roadmap for Career Management" (D. I. Riddle); (2) "A Sharing of Our Successes" (H. van Bommel); (3) "Assessing Clients with Learning Disabilities in Career Counselling" (J. B. Stewart); (4) "Career and Personal Planning: Diploma Program and Resources" (A.…

Training within Industry as Short-Sighted Community Literacy-Appropriate Training Program: A Case Study of Worker-Centered Training and Its Implications

ERIC Educational Resources Information Center

Remley, Dirk

2009-01-01

This essay presents a case study of the modes used in training employees at a munitions plant in Ohio between 1940 and 1945. Theories of multimodal discourse and learning advanced by The New London Group (1996), Gunther Kress and Theo Van Leeuwen (2001) and Richard Mayer (2001) inform this analysis. With an unskilled labor force and many workers…

Identifying the Cost of Non-monetary Incentives (ICONIC)

DTIC Science & Technology

2009-12-01

topics. a. Inspection Optimization Model The Environmental Protection Agency (EPA) developed a linear programming model designed for a state air...and other special pays that can distort the environment and amenities that the next assignment offers.23 The primary objective of this work is to...Government Printing Office, 2005). http://www.gao.gov/new.items/d06125.pdf (accessed September 28, 2008). Van Boening, Mark, Tanja F. Blackstone

US Air Force 1989 Research Initiation Program. Volume 2.

DTIC Science & Technology

1992-06-25

University of Minnesota-Duluth Specialtv: Inorganic Chemistry Specialty: Mechanics Dr. Satish Chandra Mr. Asad Yousuf Kansas State University Savannah...the Study Van der Waals forces in capillary tubes have previously been calculated by Philip (1977b]. His study was based on the Hamaker theory, which...important in condensed media, are not taken into account by the Hamaker theory. Calculations using on the Hamaker theory are often based on an unrealistic

Structuring of the Renewed Decision Making Process in the Royal Netherlands Army (Structurering van het vernieuwde besluitvormingsproces binnen de KL).

DTIC Science & Technology

1996-10-10

time informatie wordt door Eisenhardt (1989) gedefinieerd als " information about a firm’s operations or environment for which there is little or no...op het invoeren van (getypte) tekst . Conclusie Elektronisch Brainstormen: * in principe geschikt om Eigen Mogelijkheden te genereren, vooral als de...Capaieairt ca •acitenit ca a• C ie•lit Fig. 1 Mogelijke wijzen van besluitvorming (zie tekst ) als functie van beschik- bare tijd, capaciteit en ervaring van

The Design of a Propeller for a U.S. Coast Guard Icebreaker Tugboat

DTIC Science & Technology

1975-10-01

series as investigated by Van Lammeren, Van Manen , and Oosterveld . This propeller series, commonly referred to as the K’jgeningen B-screw series...RtFEKENCES Van Lammeren, W.P.A., Van Manen , J.D., and Oosterveld, M.W.C., "The Wageningen B-Screw Series," Transactions of the Society of Naval Architects...forces has been reported by Van Gunsteren and Pronk . They investigated both single and twin screw ships of various types and the results are

The Role of b-Catenin in Mammary Gland Carcinogenesis

DTIC Science & Technology

2002-03-01

Wetering, M., Cavallo, R., Dooijes, D., van Beest , M., van Es, J., Loureiro, J., Ypma, A., hursh, D., Jones, T., Bejsovec, A., Peifer, M., Mortin, M...Transduction Lab - domain of /3-catenin. oratories) and anti-KT3 (Babco) were used as primary Elevated levels of fl-catenin were recently observed in antibodies...1988). Cell, 55, 619 -625. Kolligs FT, Hu G, Dang CV and Fearon ER. (1999). Mol. van de Wetering M, Cavallo R, Dooijes D, van Beest M, van Cell. Biol

MATE (Mentale Aspecten van Team Effectiviteit) (MATE (Mental Aspects of Team Effectiveness))

DTIC Science & Technology

2008-05-01

0 Auteur (s) drs. J.P. van Meer drs. MI. 1 ’ IIart0 drs. 1. van der 16. Rubricering rapport Ongerubriceerd Vastgesteld door Ikol drs. L.A. de Vos...team Auteur (s) Teamntraining drs. J.P. van Meer drs. M.H.E. I Hart Programmanummer Projectnummer drs. 1. van der Beijl V406 015.34095 Rubricering...Murphy & Cleveland (1995) geven inzicht in de tearngedragingen die meetbaar zijn en de theorie over Shared Mental Models (Espevik et al, 2006) laat zien

De Ontwikkeling van een PBPK Model voor VX; Stand van Zaken V013-813 en 207C (The Development of a PBPK Model for VX: Status Report)

DTIC Science & Technology

2006-02-01

ing. H.C. Trap, dr. ir. M.J. van der werd zes maal gesproken over de Schans, ing. L.F. Chau, B.). Lander, invulling en de voortgang van het I.A. Cordia ...dr. ir. M.J. van der Schans, ing. L.F. Chau, J.P. Oostdijk, B.J. Lander, l.A. Cordia 25 TNO Defensie en Veiligheid, vestiging Rijswijk, Marketing en

Speed Measuring System (Detectoren en Signaalbewerking Voor Het Snelheidsmeetsysteem 4-01)

DTIC Science & Technology

1989-03-01

een hogere nauwkeurigheid te halen dan san de voet van bet signasi mogelijk is bij een grote signaalaniplitude, Wanneer de S/L < 6 is wordt de drempel...snelheidsmeetsysteem 4-01 Niets Uilf deze ultgave mag worden vermenigvuldigd en of openbaar gemaakt door mlddel van druk fotokope microfilm autour~s): of op welke...andere wijze dan 006 zonder voorafgaarode toestemming van TNO J. van der Haven Hetlter I zage geven van net TNO-rappoit aan direct belanghebbenoen is

Eisen voor Buitenbeelden van Voertuigsimulatoren: Een Literatuurstudie (Use of Exterior Pictures in Vehicle Simulators: A Literature Survey)

DTIC Science & Technology

1991-06-01

1.3 Opleiding en onderzoek met voertuigsimulatoren 9 1.4 Opbouw van simulatoren 11 1.5 Totstandkomning van beelden in CGI-systemen 13 1.6 Bepalen van...pictures in vehicle simulators. A literature survey s 029 9 20 Aantal bladzijden: 102 .JISTRIBIYI±WN- STATEMEN9 -2 39 Approved for public release; 2 28 9 ...Achteruitkijkspiegels en verrekijkers 79 8.2 Helderheidsversterkers en warmtebeelden 80 8.3 Middelen om afstand te bepalen 80 9 INTERACTIES VAN HET

Fluorescent vancomycin and terephthalate comodified europium-doped layered double hydroxides nanoparticles: synthesis and application for bacteria labelling

NASA Astrophysics Data System (ADS)

Sun, Jianchao; Fan, Hai; Wang, Nan; Ai, Shiyun

2014-09-01

Vancomycin (Van)- and terephthalate (TA)-comodified europium-doped layered double hydroxides (Van-TA-Eu-LDHs) nanoparticles were successfully prepared by a two-step method, in which, TA acted as a sensitizer to enhance the fluorescent property and Van was modified on the surface of LDH to act as an affinity reagent to bacteria. The obtained products were characterized by X-ray diffraction, transmission electron microscope and fluorescent spectroscopy. The results demonstrated that the prepared Van- and TA-comodified europium-doped layered double hydroxides (Van-TA-Eu-LDHs) nanoparticles with diameter of 50 nm in size showed highly efficient fluorescent property. Furthermore, due to the high affinity of Van to bacteria, the prepared Van-TA-Eu-LDHs nanoparticles showed efficient bacteria labelling by fluorescent property. The prepared nanoparticles may have wide applications in the biological fields, such as biomolecular labelling and cell imaging.

Defending commercial surrogate motherhood against Van Niekerk and Van Zyl.

PubMed Central

McLachlan, H V

1997-01-01

The arguments of Van Niekerk and Van Zyl that, on the grounds that it involves an inappropriate commodification and alienation of women's labour, commercial surrogate motherhood (CSM) is morally suspect are discussed and considered to be defective. In addition, doubt is cast on the notion that CSM should be illegal. PMID:9451602

Alternative Fuels Data Center: Renzenberger Inc Saves Money With Propane

Science.gov Websites

Vans Renzenberger Inc Saves Money With Propane Vans to someone by E-mail Share Alternative Fuels Data Center: Renzenberger Inc Saves Money With Propane Vans on Facebook Tweet about Alternative Fuels Data Center: Renzenberger Inc Saves Money With Propane Vans on Twitter Bookmark Alternative Fuels

77 FR 44683 - Phillips-Van Heusen Corporation, IZOD Dress Furnishings Division, New York, NY; Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

... for Reconsideration for the workers and former workers of Phillips-Van Heusen Corporation, IZOD Women... Phillips-Van Heusen Corporation, IZOD Women's Wholesale Division, New York, New York has not increased. In... Phillips-Van Heusen Corporation, IZOD Women's Wholesale Division, New York, New York) was incorrect, that...

15 CFR 30.26 - Reporting of vessels, aircraft, cargo vans, and other carriers and containers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... vehicles, trailers, pallets, cargo vans, lift vans, or similar shipping containers are not considered... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Reporting of vessels, aircraft, cargo vans, and other carriers and containers. 30.26 Section 30.26 Commerce and Foreign Trade Regulations...

15 CFR 30.26 - Reporting of vessels, aircraft, cargo vans, and other carriers and containers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... vehicles, trailers, pallets, cargo vans, lift vans, or similar shipping containers are not considered... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Reporting of vessels, aircraft, cargo vans, and other carriers and containers. 30.26 Section 30.26 Commerce and Foreign Trade Regulations...

15 CFR 30.26 - Reporting of vessels, aircraft, cargo vans, and other carriers and containers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... vehicles, trailers, pallets, cargo vans, lift vans, or similar shipping containers are not considered... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Reporting of vessels, aircraft, cargo vans, and other carriers and containers. 30.26 Section 30.26 Commerce and Foreign Trade Regulations...

15 CFR 30.26 - Reporting of vessels, aircraft, cargo vans, and other carriers and containers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... vehicles, trailers, pallets, cargo vans, lift vans, or similar shipping containers are not considered... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Reporting of vessels, aircraft, cargo vans, and other carriers and containers. 30.26 Section 30.26 Commerce and Foreign Trade Regulations...

15 CFR 30.26 - Reporting of vessels, aircraft, cargo vans, and other carriers and containers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... vehicles, trailers, pallets, cargo vans, lift vans, or similar shipping containers are not considered... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Reporting of vessels, aircraft, cargo vans, and other carriers and containers. 30.26 Section 30.26 Commerce and Foreign Trade Regulations...

UPS Hybrid Electric Delivery Van Testing | Transportation Research | NREL

Science.gov Websites

conventional diesel vans. Publications The following documents provide detailed information about the study the conventional vans during the on-road portion of the study. The two vehicle groups switched route assignments during the study period to provide a balanced review of the vans on the same routes. During

Probing the binding of phenolic aldehyde vanillin with bovine serum albumin: Evidence from spectroscopic and docking approach.

PubMed

Siddiqui, Gufran Ahmed; Siddiqi, Mohammad Khursheed; Khan, Rizwan Hasan; Naeem, Aabgeena

2018-05-08

The interactions of bovine serum albumin (BSA) with vanillin (VAN) were studied using UV-vis absorption, fluorescence, synchronous fluorescence, three dimensional fluorescence spectroscopy (3D), Fourier transform infrared spectroscopy (FTIR), circular dichroism (CD), and molecular docking techniques. The results revealed that VAN causes the static quenching of BSA by forming BSA-VAN complex. The thermodynamic parameters obtained using isothermal titration calorimetry (ITC) showed that the interaction between BSA and VAN is spontaneous and hydrogen bonding, van der Waals forces are mainly involved in stabilizing the complex. The distance between the donor and the acceptor was analyzed using fluorescence resonance energy transfer (FRET) which showed Forster distance of 2.58 nm. Molecular docking technique was applied to study the modes of interaction between BSA-VAN system and it was found that VAN bound to the sub-domain IIA of BSA. Structural analysis using 3D, synchronous fluorescence FTIR, and CD showed that upon binding of VAN, BSA exhibits small micro-environmental changes around tryptophan amino acid residue. Copyright © 2018. Published by Elsevier B.V.

Relationship of the Van Herick Grading System with Peripheral Iris Configuration and Level of Iris Insertion.

PubMed

Khan, Faisal Aziz; Niazi, Shafaq Pervez Khan; Khan, Assad Zaman

2017-09-01

To determine the relationship of the van Herick angle grading system with the level of iris insertion and peripheral iris configuration. Observational study. Eye department, Combined Military Hospital, Malir Cantt., Karachi, from May to October 2015. Sixty-five eyes of 65 patients were recruited. Anterior chamber depth at the temporal limbus was measured as a fraction of corneal section thickness using van Herick technique and graded on the standard 4-point scale of the van Herick grading system. Gonioscopy of the temporal quadrant was performed with a Posner 4 mirror goniolens and both the true level of iris insertion and peripheral iris configuration were recorded on a 4-point scale so as to equate with the van Herick 4-point grading system. Spearman's rho test was applied to determine the relationship of the van Herick grading system with level of iris root insertion and peripheral iris configuration. Amoderate positive correlation between van Herick grade and peripheral iris configuration was found which was statistically significant (rs=0.42, p < 0.001). Astatistically significant and moderate positive correlation was also detected between van Herick grade and the level of iris insertion (rs=0.45, p < 0.001). The van Herick grade has a moderately positive relationship with the peripheral iris configuration and true level of iris insertion.

Transcriptional Analysis of the vanC Cluster from Enterococcus gallinarum Strains with Constitutive and Inducible Vancomycin Resistance

PubMed Central

Panesso, Diana; Abadía-Patiño, Lorena; Vanegas, Natasha; Reynolds, Peter E.; Courvalin, Patrice; Arias, Cesar A.

2005-01-01

The vanC glycopeptide resistance gene cluster encodes enzymes required for synthesis of peptidoglycan precursors ending in d-Ala-d-Ser. Enterococcus gallinarum BM4174 and SC1 are constitutively and inducibly resistant to vancomycin, respectively. Analysis of peptidoglycan precursors in both strains indicated that UDP-MurNAc-tetrapeptide and UDP-MurNAc-pentapeptide[d-Ser] were synthesized in E. gallinarum SC1 only in the presence of vancomycin (4 μg/ml), whereas the “resistance” precursors accumulated in the cytoplasm of BM4174 cells under both inducing and noninducing conditions. Northern hybridization and reverse transcription-PCR experiments revealed that all the genes from the cluster, vanC-1, vanXYC, vanT, vanRC, and vanSC, were transcribed from a single promoter. In the inducible SC1 isolate, transcriptional regulation appeared to be responsible for inducible expression of resistance. Promoter mapping in E. gallinarum BM4174 revealed that the transcriptional start site was located 30 nucleotides upstream from vanC-1 and that the −10 promoter consensus sequence had high identity with that of the vanA cluster. Comparison of the deduced sequence of the vanSC genes from isolates with constitutive and inducible resistance revealed several amino acid substitutions located in the X box (R200L) and in the region between the F and G2 boxes (D312N, D312A, and G320S) of the putative sensor kinase proteins from isolates with constitutive resistance. PMID:15728903

Heterologous expression of glycopeptide resistance vanHAX gene clusters from soil bacteria in Enterococcus faecalis.

PubMed

Hasman, Henrik; Aarestrup, Frank M; Dalsgaard, Anders; Guardabassi, Luca

2006-04-01

The aim of the study was to determine whether glycopeptide resistance gene clusters from soil bacteria could be heterologously expressed in Enterococcus faecalis and adapt to the new host following exposure to vancomycin. The vanHAX clusters from Paenibacillus thiaminolyticus PT-2B1, Paenibacillus apiarius PA-B2B and Amycolatopsis coloradensis DSM 44225 were separately cloned in an appropriately constructed shuttle vector containing the two-component regulatory system (vanRS) of Tn1546. The complete vanA(PT) operon (vanRSHAXY) from P. thiaminolyticus PT-2B1 was cloned in the same shuttle vector lacking enterococcal vanRS. All plasmid constructs were electroporated into E. faecalis JH2-2 and the MICs of vancomycin and teicoplanin were determined for each recombinant strain before and following exposure to sublethal concentrations of vancomycin. The vanHAX clusters from P. thiaminolyticus and P. apiarius conferred high-level vancomycin resistance (MIC > or = 125 mg/L) in E. faecalis JH2-2. In contrast, cloning of the vanHAX cluster from A. coloradensis did not result in a significant increase of vancomycin resistance (MIC = 0.7 mg/L). Resistance to vancomycin was not observed after cloning the complete vanA(PT) operon from P. thiaminolyticus (MIC = 2 mg/L), but this recombinant rapidly adapted to high concentrations of vancomycin (MIC = 500 mg/L) following exposure to sub-lethal concentrations of this antibiotic. The results showed that vanA(PT) in P. thiaminolyticus is a possible ancestor of vanA-mediated glycopeptide resistance in enterococci. Experimental evidence supported the hypothesis that enterococci did not acquire glycopeptide resistance directly from glycopeptide-producing organisms such as A. coloradensis.

Comparison of Six Generic Vancomycin Products for Treatment of Methicillin-Resistant Staphylococcus aureus Experimental Endocarditis in Rabbits

PubMed Central

Tattevin, P.; Saleh-Mghir, A.; Davido, B.; Ghout, I.; Massias, L.; Garcia de la Maria, C.; Miró, J. M.; Perronne, C.; Laurent, F.

2013-01-01

Concerns have recently emerged about the potency and the quality of generic vancomycin (VAN) products approved for use in humans, based on experiments in a neutropenic mouse thigh infection model. However, other animal models may be more appropriate to decipher the bactericidal activities of VAN generics in vivo and to predict their efficacy in humans. We aimed to compare the bactericidal activities of six generic VAN products currently used in France (Mylan and Sandoz), Spain (Hospira), Switzerland (Teva), and the United States (Akorn-Strides and American Pharmaceutical Products [APP]) in a rabbit model of aortic valve endocarditis induced by 8 × 107 CFU of methicillin-resistant Staphylococcus aureus (MRSA) strain COL (VAN MIC, 1.5 μg/ml). In vitro, there were no significant differences in the time-kill curve studies performed with the six generic VAN products. Ten rabbits in each group were treated with intravenous (i.v.) VAN, 60 mg/kg of body weight twice a day (b.i.d.) for 4 days. Mean peak serum VAN levels, measured 45 min after the last injection, ranged from 35.5 (APP) to 45.9 μg/ml (Teva). Mean trough serum VAN levels, measured 12 h after the last injection, ranged from 2.3 (Hospira) to 9.2 (APP) μg/ml. All generic VAN products were superior to controls (no treatment) in terms of residual organisms in vegetations (P < 0.02 for each comparison) and in the spleen (P < 0.005 for each comparison). Pairwise comparisons of generic VAN products found no significant differences. In conclusion, a stringent MRSA endocarditis model found no significant differences in the bactericidal activities of six generic VAN products currently used in Europe and America. PMID:23254435

New taxa, including three new genera show uniqueness of Neotropical Nepticulidae (Lepidoptera)

PubMed Central

van Nieukerken, Erik J.; Doorenweerd, Camiel; Nishida, Kenji; Snyers, Chris

2016-01-01

Abstract After finding distinct clades in a molecular phylogeny for Nepticulidae that could not be placed in any known genera and discovering clear apomorphic characters that define these clades, as well as a number of Neotropical species that could be placed in known genera but were undescribed, three new genera and nine new species are here described from the Neotropics: Stigmella gallicola van Nieukerken & Nishida, sp. n. reared from galls on Hampea appendiculata (Malvaceae) in Costa Rica, representing the first example of a gall making Stigmella; Stigmella schinivora van Nieukerken, sp. n. reared from leafmines on Schinus terebinthifolia (Anacardiaceae) in Argentina, Misiones; Stigmella costaricensis van Nieukerken & Nishida, sp. n. and Stigmella intronia van Nieukerken & Nishida, sp. n. each from a single specimen collected the same night in Costa Rica, Parque Nacional Chirripó; Stigmella molinensis van Nieukerken & Snyers, sp. n. reared from leafmines on Salix humboldtiana, Peru, Lima, the first Neotropical species of the Stigmella salicis group sensu stricto; Ozadelpha van Nieukerken, gen. n. with type species Ozadelpha conostegiae van Nieukerken & Nishida, sp. n., reared from leafmines on Conostegia oerstediana (Melastomataceae) from Costa Rica; Neotrifurcula van Nieukerken, gen. n. with type species Neotrifurcula gielisorum van Nieukerken, sp. n. from Chile; Hesperolyra van Nieukerken, gen. n.. with type species Fomoria diskusi Puplesis & Robinson, 2000; Hesperolyra saopaulensis van Nieukerken, sp. n., reared from an unidentified Myrtaceae, Sao Paulo, Brasil; and Acalyptris janzeni van Nieukerken & Nishida, sp. n. from Costa Rica, Guanacaste. Five new combinations are made: Ozadelpha ovata (Puplesis & Robinson, 2000), comb. n. and Ozadelpha guajavae (Puplesis & Diškus, 2002), comb. n., Hesperolyra diskusi (Puplesis & Robinson, 2000), comb. n., Hesperolyra molybditis (Zeller, 1877), comb. n. and Hesperolyra repanda (Puplesis & Diškus, 2002), comb. n. Three specimens are briefly described, but left unnamed: Ozadelpha specimen EvN4680, Neotrifurcula specimen EvN4504 and Neotrifurcula specimen RH2. PMID:27917037

Do apolipoprotein E genotype and educational attainment predict the rate of cognitive decline in normal aging? A 12-year follow-up of the Maastricht Aging Study.

PubMed

Van Gerven, Pascal W M; Van Boxtel, Martin P J; Ausems, Eleonora E B; Bekers, Otto; Jolles, Jelle

2012-07-01

We investigated suspected longitudinal interaction effects of apolipoprotein E (APOE) genotype and educational attainment on cognitive decline in normal aging. Our sample consisted of 571 healthy, nondemented adults aged between 49 and 82 years. Linear mixed-models analyses were performed with four measurement time points: baseline, 3-year, 6-year, and 12-year follow-up. Covariates included age at baseline, sex, and self-perceived physical and mental health. Dependent measures were global cognitive functioning (Mini-Mental State Examination; Folstein, Folstein, & McHugh, 1975), Stroop performance (Stroop Color-Word Test; Van der Elst, Van Boxtel, Van Breukelen, & Jolles, 2006a), set-shifting performance (Concept Shifting Test; Van der Elst, Van Boxtel, Van Breukelen, & Jolles, 2006b), cognitive speed (Letter-Digit Substitution Test; Van der Elst, Van Boxtel, Van Breukelen, & Jolles, 2006c), verbal learning (Verbal Learning Test: Sum of five trials; Van der Elst, Van Boxtel, Van Breukelen, & Jolles, 2005), and long-term memory (Verbal Learning Test: Delayed recall). We found only faint evidence that older, high-educated carriers of the APOE-ε4 allele (irrespective of zygosity) show a more pronounced decline than younger, low-educated carriers and noncarriers (irrespective of educational attainment). Moreover, this outcome was confined to concept-shifting performance and was especially observable between 6- and 12-year follow-ups. No protective effects of higher education were found on any of the six cognitive measures. We conclude that the combination of APOE-ε4 allele and high educational attainment may be a risk factor for accelerated cognitive decline in older age, as has been reported before, but only to a very limited extent. Moreover, we conclude that, within the cognitive reserve framework, education does not have significant protective power against age-related cognitive decline.

Vancomycin resistant Enterococcus spp. from crows and their environment in metropolitan Washington State, USA: Is there a correlation between VRE positive crows and the environment?

PubMed

Roberts, Marilyn C; No, David B; Marzluff, John M; Delap, Jack H; Turner, Robert

2016-10-15

Vancomycin-resistant enterococci [VRE] have been isolated from municipal, hospital and agricultural wastewater, recreational beaches, wild animals, birds and food animals around the world. In this study, American crows (Corvus brachyrhynchos) from sewage treatment plants (WWTP), dairy farms, and a large roost in a restored wetland with corresponding environmental samples were cultured for VRE. A total of 245 samples [156 crows, 89 environmental] were collected and screened for acquired vanA, vanB and/or intrinsic vanC1 genes. Samples were enriched overnight in BHI supplemented with 20μg/mL aztreonam, 4μg/mL vancomycin and plated on m-Enterococcus agar media supplemented with 6μg/mL vancomycin. Selected colonies were grown on BHI media supplemented with 18μg/mL vancomycin. Of these, 24.5% of the crow and 55% the environmental/cow samples were VRE positive as defined by Enterococcus spp. able to grow on media supplemented with 18μg/mL vancomycin. A total of 122 VRE isolates, 43 crow and 79 environmental isolates were screened, identified to species level using 16S sequencing and further characterized. Four vanA E. faecium and multiple vanC1 E. gallinarum were identified from crows isolated from three sites. E. faecium vanA and E. gallinarum vanC1 along with other Enterococcus spp. carrying vanA, vanB, vanC1 were isolated from three environments. All enterococci were multidrug resistant. Crows were more likely to carry vanA E. faecium than either the cow feces or wetland waters/soils. Comparing E. gallinarum vanC1 from crows and their environment would be useful in determining whether crows share VRE strains with their environment. Copyright © 2016 Elsevier B.V. All rights reserved.

Computer Simulation of the Effect of Pretreatment with Reversible Acetylcholinesterase Inhibitors on the Protection Against Soman Poisoning

DTIC Science & Technology

1993-12-01

dr. U.A. Th. Brinkmnan 31* Directeur van het Medisch Biologisch Laboratorium TNO Prof. dr. W.R.F. Notten 32 PML-TNO, Directeur; daarna reserve 33 PML...Generaal Personeel Ministerie van Defensie 8* Adviseur van het Prins Maurits Laboratorium TNO Chemnische Research Prof. dr. G. Dijkstra 9* lid van de

Alternative Fuels Data Center: Natural Gas Delivery Vans Support McShan

Science.gov Websites

FloristA> Natural Gas Delivery Vans Support McShan Florist to someone by E-mail Share Alternative Natural Gas Delivery Vans Support McShan Florist Watch how a Dallas, Texas, florist reduces emissions and saves money fueling delivery vans with compressed natural gas. For information about this project

Ex ante Implementatietoetsing van Beleid, Een Methodiek Gebaseerd op Synergie Tussen Risicomanagement en Verandermanagement (Ex Ante Test for Policy Implementation - A Method Based Upon Synergy Between Risk Management an Change Management)

DTIC Science & Technology

2006-12-01

ante implementatietoetsing van beleid Een methodiek gebaseerd op synergie tussen risicomnanagemnent en verandermanagemnent Datuni december 2006 Auteur (s...te analyseren. Het de resultaten van de interviews gebruikct bij de theorie van risicomanagement en project Verandermanagernent bij de de ontwikkehing...Opdrachtnummer Hoewel expliciet is gekeken naar voorbeelden van risico’s bij Datum december 2006 Auteur (s) PROGRAMMA PR03ECT drs. R.C.T. de Haas drs

Waardering en Analyse van Simulatieresultaten (Valuation and Analysis of Simulation Results)

DTIC Science & Technology

1991-12-01

is uit de tabel van de Students T-verdeling te halen . Deze wordt aangeduid met t,(v), waarin a de overschrijdingskans en v bet aantal vrijheidsgraden...2 vrijheidsgraden. Uit de tabol van de Student’s t-verdeling zija nu de kritieke waardon R, on R2 to halen zodanig dat P(t >R2 ) = i Wordt or eon...analyse van simnulatieresultaten - TDCnaK RAPPORTE1CENTRALE Frederikkazerne, Geb. 140 AD-A25 470van den Burchlaan 31AD-A25 470Telefoon: 070-3166394

Novel type of VanB2 teicoplanin-resistant hospital-associated Enterococcus faecium.

PubMed

Santona, Antonella; Paglietti, Bianca; Al-Qahtani, Ahmed A; Bohol, Marie Fe F; Senok, Abiola; Deligios, Massimo; Rubino, Salvatore; Al-Ahdal, Mohammed N

2014-08-01

Seven high-risk clones of vancomycin-resistant Enterococcus faecium (VREF) belonging to clonal complex 17 were identified using multilocus sequence typing (MLST) among clinical isolates from Saudi Arabia. Among these isolates, a new hospital-associated sequence type (ST795), VanB(2)-type teicoplanin-resistant strain was detected. Its unusual phenotype resulted from a new combination of mutations in the ddl, vanS and vanW genes, which confirmed the trend of evolution in VanB-type resistance. Furthermore, characteristics of adaptation and persistence in the hospital environment of ST795 were emphasised by the presence of genes and clusters recognised to be specific for hospital-associated VREF. Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

Instruments of Science and Citizenship: Science Education for Dutch Orphans During the Late Eighteenth Century

NASA Astrophysics Data System (ADS)

Roberts, Lissa L.

2012-01-01

One of the two most extensive instrument collections in the Netherlands during the second half of the eighteenth century—rivaling the much better known collection at the University of Leiden—belonged to an orphanage in The Hague that was specially established to mold hand-picked orphans into productive citizens. (The other was housed at the Mennonite Seminary in Amsterdam, for use in the education of its students.) The educational program at this orphanage, one of three established by the Fundatie van Renswoude, grew out of a marriage between the socially-oriented generosity of the wealthy Baroness van Renswoude and the pedagogical vision of the institute's director and head teacher—a vision that fit with the larger movement of oeconomic patriotism. Oeconomic patriotism, similar to `improvement' and oeconomic movements in other European countries and their colonies, sought to tie the investigation of nature to an improvement of society's material and moral well-being. Indeed, it was argued that these two facets of society should be viewed as inseparable from each other, distinguishing the movement from more modern conceptions of economics. While a number of the key figures in this Dutch movement also became prominent Patriots during the revolutionary period at the end of the century, fighting against the House of Orange, they did not have a monopoly on oeconomic ideas of societal improvement. This is demonstrated by the fact that an explicitly pro-Orangist society, Mathesis Scientiarum Genitrix, was organized in 1785 to teach science and mathematics to poor boys and orphans for very similar reasons: to turn them into productive and useful citizens. As was the case with the Fundatie van Renswoude, a collection of instruments was assembled to help make this possible. This story is of interest because it discusses a hitherto under-examined use to which science education was put during this period, by revealing the link between such programs and the highly charged question of citizenry.

Doublet Pulse Coherent Laser Radar for Tracking of Resident Space Objects

DTIC Science & Technology

2014-09-01

based laser systems can be limited by the effects of tumbling, extremely accurate Doppler measurement is possible using a doublet coherent laser ...Doublet pulse coherent laser radar for tracking of resident space objects Narasimha S. Prasad *1 , Van Rudd 2 , Scott Shald 2 , Stephan...Doublet Pulse Coherent Laser Radar for Tracking of Resident Space Objects 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S

A Tamper-Resistant Programming Language System

DTIC Science & Technology

2006-06-02

www.cs.ucsb.edu/~vigna/listpub.html). [15] Gassend, B ., D. Clarke, M. van Dijk, S. Devadas , and E. Suh, “Caches and Merkle Trees for Efficient Memory...CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 23 19a. NAME OF RESPONSIBLE PERSON a. REPORT unclassified b . ABSTRACT...winhec/papers03.mspx). [3] Barak, B ., O. Goldreich, R. Impagliazzo, S. Rudich, A. Sahai, S. Vadhan, and K.Yang, “On the (Im)possibility of Obfuscating

Environmental Impact Research Program. An Instruction Report on Freshwater Mussels.

DTIC Science & Technology

1983-09-01

34Greater Adaptability of Fresh-Water Mussels to Natural Rather Than to Artificial Displacement," The Nautilus Vol 86, pp 76-79. Isom, B. G. 1980...cotizing and Anaesthetizing Gastropods ," Malacologia 2: 231-238. van der Schalie, H. 1953. "Nembutal as a Relaxing Agent for Mollusks," The American...of Philadelphia, Philadelphia, Pa. Imlay, M. J. 1972. "Greater Adaptability of Freshwater Mussels to Natural Rather Than to Artificial Displacement

Perceptions and Development of Political Leadership Skills of Women in Academic Medicine: A Study of Selected Women Alumnae of the Hedwig Van Ameringen Executive Leadership in Academic Medicine (ELAM) Program

ERIC Educational Resources Information Center

Evers, Cynthia D.

2014-01-01

Despite women having much to offer in the field of academic medicine, women may not be sufficiently attuned to developing their political leadership skills, which are crucial for successful leadership (Ferris, Frink, & Galang, 1993; Ferris & Perrewe, 2010). The study's purpose was to examine how 14 women in academic medicine perceived…

In Vivo Fluorescence Confocal Microscopy to Investigate the Role of RhoC in Inflammatory Breast Cancer

DTIC Science & Technology

2005-11-01

5084. 6. Colpaert CG, Vermeulen PB, Benoy I, Soubry A, van Roy F, van Beest P, Goovaerts G, Dirix LY, van Dam P, Fox SB, Harris AL, van MarckEA...small GTPases, RhoA and RhoC, is associ- inflammatory breast cancer. Clin Exp Metastasis 2002, ated with tumor progression in ovarian carcinoma. Lab

Design and mechanistic study of a novel gold nanocluster-based drug delivery system.

PubMed

Li, Qinzhen; Pan, Yiting; Chen, Tiankai; Du, Yuanxin; Ge, Honghua; Zhang, Buchang; Xie, Jianping; Yu, Haizhu; Zhu, Manzhou

2018-05-22

Chemically-triggered drug delivery systems (DDSs) have been extensively studied as they do not require specialized equipment to deliver the drug and can deeply penetrate human tissue. However, their syntheses are complicated and they tend to be cytotoxic, which restricts their clinical utility. In this work, the self-regulated drug loading and release capabilities of peptide-protected gold nanoclusters (Pep-Au NCs) are investigated using vancomycin (Van) as the model drug. Gold nanoclusters (Au NCs) coated with a custom-designed pentapeptide are synthesized as drug delivery nanocarriers and loaded with Van - a spontaneous process reliant on the specific binding between Van and the custom-designed peptide. The Van-loaded Au NCs show comparable antimicrobial activity with Van on its own, and the number of Van released by the Pep-Au NCs is found to be proportional to the amount of bacteria present. The controlled nature of the Van release is very encouraging, and predominantly due to the stronger binding affinity of Van with bacteria than that with Au NCs. In addition, these fluorescent Au NCs could also be used to construct temperature sensors, which enable the in vitro and in vivo bioimaging.

Vanilla mosaic virus isolates from French Polynesia and the Cook Islands are Dasheen mosaic virus strains that exclusively infect vanilla.

PubMed

Farreyrol, K; Pearson, M N; Grisoni, M; Cohen, D; Beck, D

2006-05-01

Sequence was determined for the coat protein (CP) gene and 3' non-translated region (3'NTR) of two vanilla mosaic virus (VanMV) isolates from Vanilla tahitensis, respectively from the Cook Islands (VanMV-CI) and French Polynesia (VanMV-FP). Both viruses displayed distinctive features in the N-terminal region of their CPs; for VanMV-CI, a 16-amino-acid deletion including the aphid transmission-related DAG motif, and for VanMV-FP, a stretch of GTN repeats that putatively belongs to the class of natively unfolded proteins. VanMV-FP CP also has a novel DVG motif in place of the DAG motif, and an uncommon Q//V protease cleavage site. The sequences were compared to a range of Dasheen mosaic virus (DsMV) strains and to potyviruses infecting orchids. Identity was low to DsMV strains across the entire CP coding region and across the 3'NTR, but high across the CP core and the CI-6K2-NIa region. In accordance with current ICTV criteria for species demarcation within the family Potyviridae, VanMV-CI and VanMV-FP are strains of DsMV that exclusively infect vanilla.

Van der waals forces on thin liquid films in capillary tubes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herdt, G.C.; Swanson, L.W.

1993-10-01

A theory of the van der Waals attraction between a thin liquid films and a capillary tube is presented assuming the presence of a vapor-liquid interface. The model is based on the surface mode analysis method of van Kampen et al. Values for the van der Waals interaction energy per unit area were calculated for liquid films of pentane on a gold substrate assuming a thin liquid film. Results indicate that the effect of capillary curvature on the van der Waals interaction increases as the ratio of the liquid film thickness to the capillary radius is increased. This trend ismore » consistent with predictions based on the Hamaker theory. Deviations from results based on the Hamaker theory are easily explained in terms of retardation of the van der Waals interaction. Because the effect of capillary curvature increases in the regime where retardation effects become important, curvature effects constitute a small correction to the van der Waals forces in a capillary tube.« less

Accuracy of the VITEK 2 System To Detect Glycopeptide Resistance in Enterococci

PubMed Central

van den Braak, Nicole; Goessens, Wil; van Belkum, Alex; Verbrugh, Henri A.; Endtz, Hubert P.

2001-01-01

We evaluated the accuracy of the VITEK 2 fully automated system to detect and identify glycopeptide-resistant enterococci (GRE) compared to a reference agar dilution method. The sensitivity of vancomycin susceptibility testing with VITEK 2 for the detection of vanA, vanB, and vanC1 strains was 100%. The sensitivity of vancomycin susceptibility testing of vanC2 strains was 77%. The sensitivity of teicoplanin susceptibility testing of vanA strains was 90%. Of 80 vanC enterococci, 78 (98%) were correctly identified by VITEK 2 as Enterococcus gallinarum/Enterococcus casseliflavus. Since the identification and susceptibility data are produced within 3 and 8 h, respectively, VITEK 2 appears a fast and reliable method for detection of GRE in microbiology laboratories. PMID:11136798

First complete genome sequence of vanilla mosaic strain of Dasheen mosaic virus isolated from the Cook Islands.

PubMed

Puli'uvea, Christopher; Khan, Subuhi; Chang, Wee-Leong; Valmonte, Gardette; Pearson, Michael N; Higgins, Colleen M

2017-02-01

We present the first complete genome of vanilla mosaic virus (VanMV). The VanMV genomic structure is consistent with that of a potyvirus, containing a single open reading frame (ORF) encoding a polyprotein of 3139 amino acids. Motif analyses indicate the polyprotein can be cleaved into the expected ten individual proteins; other recognised potyvirus motifs are also present. As expected, the VanMV genome shows high sequence similarity to the published Dasheen mosaic virus (DsMV) genome sequences; comparisons with DsMV continue to support VanMV as a vanilla infecting strain of DsMV. Phylogenetic analyses indicate that VanMV and DsMV share a common ancestor, with VanMV having the closest relationship with DsMV strains from the South Pacific.

Simulations of pattern dynamics for reaction-diffusion systems via SIMULINK

PubMed Central

2014-01-01

Background Investigation of the nonlinear pattern dynamics of a reaction-diffusion system almost always requires numerical solution of the system’s set of defining differential equations. Traditionally, this would be done by selecting an appropriate differential equation solver from a library of such solvers, then writing computer codes (in a programming language such as C or Matlab) to access the selected solver and display the integrated results as a function of space and time. This “code-based” approach is flexible and powerful, but requires a certain level of programming sophistication. A modern alternative is to use a graphical programming interface such as Simulink to construct a data-flow diagram by assembling and linking appropriate code blocks drawn from a library. The result is a visual representation of the inter-relationships between the state variables whose output can be made completely equivalent to the code-based solution. Results As a tutorial introduction, we first demonstrate application of the Simulink data-flow technique to the classical van der Pol nonlinear oscillator, and compare Matlab and Simulink coding approaches to solving the van der Pol ordinary differential equations. We then show how to introduce space (in one and two dimensions) by solving numerically the partial differential equations for two different reaction-diffusion systems: the well-known Brusselator chemical reactor, and a continuum model for a two-dimensional sheet of human cortex whose neurons are linked by both chemical and electrical (diffusive) synapses. We compare the relative performances of the Matlab and Simulink implementations. Conclusions The pattern simulations by Simulink are in good agreement with theoretical predictions. Compared with traditional coding approaches, the Simulink block-diagram paradigm reduces the time and programming burden required to implement a solution for reaction-diffusion systems of equations. Construction of the block-diagram does not require high-level programming skills, and the graphical interface lends itself to easy modification and use by non-experts. PMID:24725437

Simulations of pattern dynamics for reaction-diffusion systems via SIMULINK.

PubMed

Wang, Kaier; Steyn-Ross, Moira L; Steyn-Ross, D Alistair; Wilson, Marcus T; Sleigh, Jamie W; Shiraishi, Yoichi

2014-04-11

Investigation of the nonlinear pattern dynamics of a reaction-diffusion system almost always requires numerical solution of the system's set of defining differential equations. Traditionally, this would be done by selecting an appropriate differential equation solver from a library of such solvers, then writing computer codes (in a programming language such as C or Matlab) to access the selected solver and display the integrated results as a function of space and time. This "code-based" approach is flexible and powerful, but requires a certain level of programming sophistication. A modern alternative is to use a graphical programming interface such as Simulink to construct a data-flow diagram by assembling and linking appropriate code blocks drawn from a library. The result is a visual representation of the inter-relationships between the state variables whose output can be made completely equivalent to the code-based solution. As a tutorial introduction, we first demonstrate application of the Simulink data-flow technique to the classical van der Pol nonlinear oscillator, and compare Matlab and Simulink coding approaches to solving the van der Pol ordinary differential equations. We then show how to introduce space (in one and two dimensions) by solving numerically the partial differential equations for two different reaction-diffusion systems: the well-known Brusselator chemical reactor, and a continuum model for a two-dimensional sheet of human cortex whose neurons are linked by both chemical and electrical (diffusive) synapses. We compare the relative performances of the Matlab and Simulink implementations. The pattern simulations by Simulink are in good agreement with theoretical predictions. Compared with traditional coding approaches, the Simulink block-diagram paradigm reduces the time and programming burden required to implement a solution for reaction-diffusion systems of equations. Construction of the block-diagram does not require high-level programming skills, and the graphical interface lends itself to easy modification and use by non-experts.

Identification of VanN-type vancomycin resistance in an Enterococcus faecium isolate from chicken meat in Japan.

PubMed

Nomura, Takahiro; Tanimoto, Koichi; Shibayama, Keigo; Arakawa, Yoshichika; Fujimoto, Shuhei; Ike, Yasuyoshi; Tomita, Haruyoshi

2012-12-01

Five VanN-type vancomycin-resistant Enterococcus faecium strains were isolated from a sample of domestic chicken meat in Japan. All isolates showed low-level resistance to vancomycin (MIC, 12 mg/liter) and had the same pulsed-field gel electrophoresis profile. The vancomycin resistance was encoded on a large plasmid (160 kbp) and was expressed constitutively. The VanN-type resistance operon was identical to the first resistance operon to be reported, with the exception of a 1-bp deletion in vanT(N) and a 1-bp substitution in vanS(N).

Review of Gasteruption Latreille (Hymenoptera, Gasteruptiidae) from Iran and Turkey, with the description of 15 new species

PubMed Central

van Achterberg, Cornelis; Talebi, Ali Asghar

2014-01-01

Abstract The genus Gasteruption Latreille, 1796 (Hymenoptera: Evanioidea: Gasteruptiidae: Gasteruptiinae) from North Iran and Turkey is revised, keyed and fully illustrated for the first time. In total 36 species are treated of which 33 are recorded from Turkey and 23 from Iran. Fifteen species are new for science: Gasteruption aciculatum van Achterberg, sp. n., Gasteruption agrenum van Achterberg, sp. n., Gasteruption brevibasale van Achterberg & Saure, sp. n., Gasteruption coriacoxale van Achterberg, sp. n., Gasteruption flavimarginatum van Achterberg, sp. n., Gasteruption heminitidum van Achterberg, sp. n., Gasteruption henseni van Achterberg, sp. n., Gasteruption ischnolaimum van Achterberg, sp. n., Gasteruption nigrapiculatum van Achterberg, sp. n., Gasteruption paglianoi van Achterberg & Saure, sp. n., Gasteruption pseudolaticeps van Achterberg, sp. n., Gasteruption punctifrons van Achterberg, sp. n., Gasteruption schmideggeri van Achterberg & Saure, sp. n., Gasteruption scorteum van Achterberg, sp. n. and Gasteruption smitorum van Achterberg, sp. n. Twenty-one species are reported new for Turkey and 16 species new for Iran. Fifteen new synonyms are proposed: Foenus terrestris Tournier, 1877, Gasteruption trifossulatum Kieffer, 1904, and Gasteruption ignoratum Kieffer, 1912, of Gasteruption caucasicum (Guérin-Méneville, 1844); Gasteruption daisyi Alekseev, 1993, of Gasteruption dolichoderum Schletterer, 1889; Gasteruption assectator var. nitidulum Schletterer, 1885, of Gasteruption freyi (Tournier, 1877); Gasteruption schossmannae Madl, 1987, of Gasteruption hastator (Fabricius, 1804); Gasteryption fallaciosum Semenov, 1892, Gasteruption dubiosum Semenov, 1892 and Gasteruption obsoletum Semenov, 1892, of Gasteruption insidiosum Semenov, 1892; Gasteryption schewyrewi Semenov, 1892, of Gasteruption jaculator (Linnaeus, 1758); Gasteruption floreum Szépligeti, 1903, of Gasteruption lugubre Schletterer, 1889; Gasteruption trichotomma Kieffer, 1904, and Gasteruption palaestinum Pic, 1916, of Gasteruption merceti Kieffer, 1904; Gasteryption foveiceps Semenov, 1892, of Gasteruption nigrescens Schletterer, 1885, and Gasteruption libanense Pic, 1916, of Gasteruption syriacum Szépligeti, 1903. Gasteruption lugubre Schletterer, 1889, is recognised as a valid species. Lectotypes are designated for Ichneumon assectator Linnaeus, 1758; Ichneumon jaculator Linnaeus, 1758; Foenus terrestris Tournier, 1877; Foenus freyi Tournier, 1877; Foenus nigripes Tournier, 1877; Foenus goberti Tournier, 1877; Foenus granulithorax Tournier, 1877; Foenus minutus Tournier, 1877; Foenus borealis Thomson, 1883; Faenus diversipes Abeille de Perrin, 1879; Foenus rugulosus Abeille de Perrin, 1879; Faenus obliteratus Abeille de Perrin, 1879; Faenus undulatum Abeille de Perrin, 1879; Faenus variolosus Abeille de Perrin, 1879; Gasteruption distinguendum Schletterer, 1885; Gasteruption laeviceps Schletterer, 1885; Gasteruption thomsonii Schletterer, 1885; Gasteruption foveolatum Schletterer, 1889; Gasteruption sowae Schletterer, 1901; Gasteruption foveolum Szépligeti, 1903; Gasteruption floreum Szépligeti, 1903; Gasteruption caudatum Szépligeti, 1903; Gasteruption syriacum Szépligeti, 1903; Gasteruption merceti Kieffer, 1904 and Gasteruption ignoratum Kieffer, 1912. A neotype is designated for Gasteruption tournieri Schletterer, 1885. PMID:25561849

Characterization of a developmental toxicity dose-response model.

PubMed Central

Faustman, E M; Wellington, D G; Smith, W P; Kimmel, C A

1989-01-01

The Rai and Van Ryzin dose-response model proposed for teratology experiments has been characterized for its appropriateness and applicability in modeling the dichotomous response data from developmental toxicity studies. Modifications were made in the initial probability statements to reflect more accurately biological events underlying developmental toxicity. Data sets used for the evaluation were obtained from the National Toxicology Program and U.S. EPA laboratories. The studies included developmental evaluations of ethylene glycol, diethylhexyl phthalate, di- and triethylene glycol dimethyl ethers, and nitrofen in rats, mice, or rabbits. Graphic examination and statistical evaluation demonstrate that this model is sensitive to the data when compared to directly measured experimental outcomes. The model was used to interpolate to low-risk dose levels, and comparisons were made between the values obtained and the no-observed-adverse-effect levels (NOAELs) divided by an uncertainty factor. Our investigation suggests that the Rai and Van Ryzin model is sensitive to the developmental toxicity end points, prenatal deaths, and malformations, and appears to model closely their relationship to dose. PMID:2707204

Quantum Monte Carlo Studies of Bulk and Few- or Single-Layer Black Phosphorus

NASA Astrophysics Data System (ADS)

Shulenburger, Luke; Baczewski, Andrew; Zhu, Zhen; Guan, Jie; Tomanek, David

2015-03-01

The electronic and optical properties of phosphorus depend strongly on the structural properties of the material. Given the limited experimental information on the structure of phosphorene, it is natural to turn to electronic structure calculations to provide this information. Unfortunately, given phosphorus' propensity to form layered structures bound by van der Waals interactions, standard density functional theory methods provide results of uncertain accuracy. Recently, it has been demonstrated that Quantum Monte Carlo (QMC) methods achieve high accuracy when applied to solids in which van der Waals forces play a significant role. In this talk, we will present QMC results from our recent calculations on black phosphorus, focusing on the structural and energetic properties of monolayers, bilayers and bulk structures. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. DOE's National Nuclear Security Administration under Contract DE-AC04-94AL85000.

Revision of the family Chalcididae (Hymenoptera, Chalcidoidea) from Vietnam, with the description of 13 new species

PubMed Central

Narendran, T. C.; van Achterberg, Cornelis

2016-01-01

Abstract A total of 16 genera and 68 species of Chalcididae of Vietnam are taxonomically treated. Thirteen new species are described; the remaining 55 species are keyed, redescribed or provided with a diagnosis. Among these 37 species and eleven genera are recorded for the first time from Vietnam. The thirteen new species are: Antrocephalus neogalleriae Narendran & van Achterberg, sp. n.; Brachymeria neowiebesina Narendran & van Achterberg, sp. n., Brachymeria semirusula Narendran & van Achterberg, sp. n., Dirhinus neoclaviger Narendran & van Achterberg, sp. n., Epitranus narendrani van Achterberg, sp. n., Epitranus neonigriceps Narendran & van Achterberg, sp. n., Heydoniella vietnamensis Narendran & van Achterberg, sp. n., Megachalcis vietnamicus Narendran & van Achterberg, sp. n., Notaspidium vietnamicum Narendran & van Achterberg, sp. n., Oxycoryphe neotenax Narendran & van Achterberg, sp. n., Sthulapada neopadata Narendran & van Achterberg, sp. n., Sthulapada vietnamensis Narendran & van Achterberg, sp. n., and Tanycoryphus masii Narendran & van Achterberg, sp. n. The newly recorded genera are: Antrocephalus Kirby, 1883; Haltichella Spinola, 1811; Heydoniella Narendran, 2003; Hockeria Walker, 1834; Kriechbaumerella Dalla Torre, 1894; Notaspidium Dalla Torre, 1897; Oxycoryphe Kriechbaumer, 1894; Psilochalcis Kieffer, 1904; Sthulapada Narendran, 1989; Tanycorphus Cameron, 1905, and Trigonura Sichel, 1865. The following known species are recorded for the first time from Vietnam: Antrocephalus decipiens (Masi, 1929); Antrocephalus lugubris (Masi, 1932); Antrocephalus maculipennis (Cameron, 1905); Antrocephalus nasutus (Holmgren, 1869); Antrocephalus sepyra (Walker, 1846); Antrocephalus validicornis (Holmgren, 1868); Brachymeria alternipes (Walker, 1871); Brachymeria aurea (Girault, 1915); Brachymeria coxodentata Joseph, Narendran & Joy, 1972; Brachymeria euploeae (Westwood, 1837); Brachymeria hime Habu, 1960; Brachymeria jambolana Gahan, 1942; Brachymeria kamijoi Habu, 1960; Brachymeria lugubris (Walker, 1871); Brachymeria marmonti (Girault, 1924); Brachymeria minuta (Linnaeus, 1767); Brachymeria scutellocarinata Joseph, Narendran & Joy, 1972; Brachymeria shansiensis Habu, 1961; Brachymeria taiwana (Matsumura, 1910); Dirhinus anthracia Walker, 1846; Dirhinus claviger Bouček & Narendran, 1981; Epitranus albipennis Walker, 1874; Epitranus ater Bouček, 1982; Epitranus gauldi Bouček, 1982; Epitranus oxytelus Bouček, 1982; Epitranus ramnathi (Mani & Dubey, 1973); Haltichella delhensis Roy & Farooqi, 1984; Haltichella nipponensis Habu, 1960; Hockeria bangalorica Narendran, 1989; Hockeria guptai Narendran, 1989; Kriechbaumerella ayyari (Gahan, 1919); Kriechbaumerella cordigaster Roy & Farooqi, 1984; Kriechbaumerella destructor (Waterston, 1922); Kriechbaumerella nepalensis Narendran, 1989; Oxycoryphe scutellatus Narendran, 1989; Psilochalcis carinigena (Cameron, 1907), and Trigonura luzonensis Narendran, 1987. Brachymeria calopeplae Joseph, Narendran & Joy, 1972, is treated as a valid species. PMID:27110185

Investigating the Effect of van Hiele Phase-Based Instruction on Pre-Service Teachers' Geometric Thinking

ERIC Educational Resources Information Center

Armah, Robert Benjamin; Cofie, Primrose Otokonor; Okpoti, Christopher Adjei

2018-01-01

This study investigated the effect of van Hiele Phase-based Instruction (VHPI) on Ghanaian Pre-service Teachers' (PTs') geometric thinking in terms of the van Hiele Levels. A pre-test post-test quasi-experimental design was employed. There were 75 PTs each in the experimental group and the control group. Van Hiele Geometry Test (VHGT) was…

Experimental Testing of a Van De Graaff Generator as an Electromagnetic Pulse Generator

DTIC Science & Technology

2016-07-01

EXPERIMENTAL TESTING OF A VAN DE GRAAFF GENERATOR AS AN ELECTROMAGNETIC PULSE GENERATOR THESIS...protection in the United States AFIT-ENP-MS-16-S-075 EXPERIMENTAL TESTING OF A VAN DE GRAAFF GENERATOR AS AN ELECTROMAGNETIC PULSE GENERATOR...RELEASE; DISTRIBUTION UNLIMITED. AFIT-ENP-MS-16-S-075 EXPERIMENTAL TESTING OF A VAN DE GRAAFF GENERATOR AS AN ELECTROMAGNETIC PULSE GENERATOR

78 FR 47817 - Parts and Accessories Necessary for Safe Operation; Application for an Exemption From Van Hool N...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-06

....V. and Coach USA AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of... exemption from Van Hool N.V. and Coach USA (Van Hool/Coach USA) to allow the use of double deck motorcoaches..., Van Hool/Coach USA is requesting an exemption that would allow the use of sleeper berths that comply...

Alternating current impedance spectroscopic analysis of biofunctionalized vertically-aligned silica nanospring surface for biosensor applications

NASA Astrophysics Data System (ADS)

Timalsina, Yukta P.

In this dissertation, a process of vertically-aligned (silica) nanosprings (VANS) based biosensor development is presented. Alternating current (AC) impedance spectroscopy has been used to analyze sensor response as a function of saline phosphate (SP) buffer and biological solutions. The sensor is a parallel plate capacitor consisting of two glass substrates coated with indium tin oxide (ITO), where the VANS [or randomly-aligned nanosprings (RANS)] grown on one substrate serve as the dielectric spacer layer. The response of a VANS device as a function of ionic concentration in SP buffer was examined and an equivalent circuit model was developed. The results demonstrated that VANS sensors exhibited greater sensitivity to the changes in SP concentration relative to the ITO sensors, which serve as controls. The biofunctionalized VANS surface via physisorption and the cross-linker method demonstrates the repeatability, specificity, and selectivity of the binding. The physisorption of biotinylated immunoglobulin G (B-IgG) onto the VANS surface simplifies the whole sensing procedure for the detection of glucose oxidase, since the avidin-conjugated glucose oxidase (Av-GOx) can directly be immobilized on the B-IgG. The cross linker method involves the covalent attachment of antibodies onto the functionalized VANS surface via imine bond. The experiments revealed that the VANS sensor response is solely the result of the interaction of target molecule i.e. mouse IgG with the probe layer, i.e. goat antimouse IgG (GalphaM IgG). It was determined that VANS-based sensors exhibit a greater magnitude of change between successive bio-layers relative to the controls above 100 Hz, which indicates that the addition of biomolecules inhibits the diffusion of ions and changes the effective dielectric response of the VANS via biomolecular polarization. The study of ionic transport in nanosprings suggested that conductance follows a scaling law. It was demonstrated that a VANS-based device exhibits a greater magnitude of change relative to the RANS device below 10 kHz, which has equivalent property of the ITO controls. This dissertation demonstrates the potential for VANS as a novel nanomaterial platform for the development of highly sensitive, selective, low cost, and label free biosensors.

Mathematical foundations of the dendritic growth models.

PubMed

Villacorta, José A; Castro, Jorge; Negredo, Pilar; Avendaño, Carlos

2007-11-01

At present two growth models describe successfully the distribution of size and topological complexity in populations of dendritic trees with considerable accuracy and simplicity, the BE model (Van Pelt et al. in J. Comp. Neurol. 387:325-340, 1997) and the S model (Van Pelt and Verwer in Bull. Math. Biol. 48:197-211, 1986). This paper discusses the mathematical basis of these models and analyzes quantitatively the relationship between the BE model and the S model assumed in the literature by developing a new explicit equation describing the BES model (a dendritic growth model integrating the features of both preceding models; Van Pelt et al. in J. Comp. Neurol. 387:325-340, 1997). In numerous studies it is implicitly presupposed that the S model is conditionally linked to the BE model (Granato and Van Pelt in Brain Res. Dev. Brain Res. 142:223-227, 2003; Uylings and Van Pelt in Network 13:397-414, 2002; Van Pelt, Dityatev and Uylings in J. Comp. Neurol. 387:325-340, 1997; Van Pelt and Schierwagen in Math. Biosci. 188:147-155, 2004; Van Pelt and Uylings in Network. 13:261-281, 2002; Van Pelt, Van Ooyen and Uylings in Modeling Dendritic Geometry and the Development of Nerve Connections, pp 179, 2000). In this paper we prove the non-exactness of this assumption, quantify involved errors and determine the conditions under which the BE and S models can be separately used instead of the BES model, which is more exact but considerably more difficult to apply. This study leads to a novel expression describing the BE model in an analytical closed form, much more efficient than the traditional iterative equation (Van Pelt et al. in J. Comp. Neurol. 387:325-340, 1997) in many neuronal classes. Finally we propose a new algorithm in order to obtain the values of the parameters of the BE model when this growth model is matched to experimental data, and discuss its advantages and improvements over the more commonly used procedures.

Evaluation of risk factors for vancomycin-induced nephrotoxicity.

PubMed

Park, So Jin; Lim, Na Ri; Park, Hyo Jung; Yang, Jae Wook; Kim, Min-Ji; Kim, Kyunga; In, Yong Won; Lee, Young Mee

2018-05-09

Background Vancomycin is a glycopeptide antibiotic of choice for the treatment of serious infections caused by multi-resistant Gram-positive bacteria. However, vancomycin-associated nephrotoxicity (VAN) often limits its use. Previous data suggested a few risk factors of VAN, including higher mean vancomycin trough level, higher daily doses, old age, long duration of vancomycin therapy, and concomitant nephrotoxins. Objective To evaluate the incidence and risk factors of VAN and determine whether higher vancomycin trough concentrations were associated with a greater risk for VAN. Settings A retrospective, observational, single-center study at the 1960-bed university-affiliated tertiary care hospital (Samsung Medical Center), Seoul, Korea. Method A retrospective analysis of adult patients who received vancomycin parenterally in a tertiary care medical center from March 1, 2013 to June 30, 2013 was performed. We excluded patients with a baseline serum creatinine level > 2 mg/dL and those who had a history of end-stage renal disease and dialysis at baseline. The clinical characteristics were compared between patients with nephrotoxicity and those without nephrotoxicity to identify the risk factors associated with VAN. Main outcome measure Incidence of VAN and VAN-associated risk factors were analyzed. Results Of the 315 vancomycin-treated patients, nephrotoxicity occurred in 15.2% of the patients. In multivariate analysis, higher vancomycin trough concentrations of > 20 mg∕L (OR 9.57, 95% CI 2.49-36.83, p < 0.01) and intensive care unit (ICU) residence (OR 2.86, 95% CI 1.41-5.82, p < 0.01) were independently associated with VAN. Conclusion Our findings suggest that higher vancomycin trough levels and ICU residence might be associated with a greater risk for VAN. More careful monitoring of vancomycin serum trough levels and patient status might facilitate the timely prevention of VAN.

Genetics Home Reference: dihydropyrimidine dehydrogenase deficiency

MedlinePlus

... NG, Bakker HD, Meinsma R, Van Lenthe H, De Abreu RA, Smeitink JA, Kayserili H, Apak MY, ... 9. Review. Citation on PubMed van Kuilenburg AB, De Abreu RA, van Gennip AH. Pharmacogenetic and clinical ...

Building Cultural Capability for Full-Spectrum Operations

DTIC Science & Technology

2008-01-01

Mol, Born, Willemsen, & Van der Molen , 2005; Caligiuri & Day, 2000). In addition to these broad traits, antecedents to cross-cultural competence...510-517. 18 Mol, S. T., Born, M. P., Willemsen, M. E., & Van Der Molen , H. T. (2005). Predicting expatriate job performance for selection purposes: A...et al., 2003). In addition, self-regulation has been shown to be critical for adjustment (Matsumoto et al., 2003; van Oudenhoven, Mol, & Van der Zee

Selective Perception for Robot Driving

DTIC Science & Technology

1992-05-01

models are theories of human cognitive activity during driving. Van der Molen and Botticher recently reviewed several of these models [ van der Molen 871...how to represent driving knowledge, how to perceive traffic situations, or how to process information to obtain actions. Van der Molen and Botticher...attempted to compare the operations of various models objectively on the same task [Rothengatter 88, van der Molen 87], but the models could be

Quality of Life for Adults with Asthma in a Military Setting

DTIC Science & Technology

1998-05-01

Tilley, Havstead, & Zoratti, 1997). More recently, van der Molen , et al. (1997) conducted a study comparing discriminative aspects of two generic...Symptom Management Faculty Group, UCSF. (1994). IMAGE: Journal of Nursing Scholarship, 26(4), 272-276. van der Molen , T., Postma, D., Schreuers, A...the most important (Earwood, 1996, Rutten- Van Molken, Van Doorslaer, & Rutten, 1992). Purpose of the Study When patients clarify their perceptions of

Rater Biases in Genetically Informative Research Designs: Comment on Bartels, Boomsma, Hudziak, van Beijsterveldt, and van den Oord (2007)

ERIC Educational Resources Information Center

Hoyt, William T.

2007-01-01

Rater biases are of interest to behavior genetic researchers, who often use ratings data as a basis for studying heritability. Inclusion of multiple raters for each sibling pair (M. Bartels, D. I. Boomsma, J. J. Hudziak, T. C. E. M. van Beijsterveldt, & E. J. C. G. van den Oord, 2007) is a promising strategy for controlling bias variance and may…

Application of Diffusion Monte Carlo to Materials Dominated by van der Waals Interactions

DOE PAGES

Benali, Anouar; Shulenburger, Luke; Romero, Nichols A.; ...

2014-06-12

Van der Waals forces are notoriously difficult to account for from first principles. We perform extensive calculation to assess the usefulness and validity of diffusion quantum Monte Carlo when applied to van der Waals forces. We present results for noble gas solids and clusters - archetypical van der Waals dominated assemblies, as well as a relevant pi-pi stacking supramolecular complex: DNA + intercalating anti-cancer drug Ellipticine.

[Mobile hospital -real time mobile telehealthcare system with ultrasound and CT van using high-speed satellite communication-].

PubMed

Takizawa, Masaomi; Miyashita, Toyohisa; Murase, Sumio; Kanda, Hirohito; Karaki, Yoshiaki; Yagi, Kazuo; Ohue, Toru

2003-01-01

A real-time telescreening system is developed to detect early diseases for rural area residents using two types of mobile vans with a portable satellite station. The system consists of a satellite communication system with 1.5Mbps of the JCSAT-1B satellite, a spiral CT van, an ultrasound imaging van with two video conference system, a DICOM server and a multicast communication unit. The video image and examination image data are transmitted from the van to hospitals and the university simultaneously. Physician in the hospital observes and interprets exam images from the van and watches the video images of the position of ultrasound transducer on screenee in the van. After the observation images, physician explains a results of the examination by the video conference system. Seventy lung CT screening and 203 ultrasound screening were done from March to June 2002. The trial of this real time screening suggested that rural residents are given better healthcare without visit to the hospital. And it will open the gateway to reduce the medical cost and medical divide between city area and rural area.

DdlN from Vancomycin-Producing Amycolatopsis orientalis C329.2 Is a VanA Homologue with d-Alanyl-d-Lactate Ligase Activity

PubMed Central

Marshall, C. Gary; Wright, Gerard D.

1998-01-01

Vancomycin-resistant enterococci acquire high-level resistance to glycopeptide antibiotics through the synthesis of peptidoglycan terminating in d-alanyl-d-lactate. A key enzyme in this process is a d-alanyl-d-alanine ligase homologue, VanA or VanB, which preferentially catalyzes the synthesis of the depsipeptide d-alanyl-d-lactate. We report the overexpression, purification, and enzymatic characterization of DdlN, a VanA and VanB homologue encoded by a gene of the vancomycin-producing organism Amycolatopsis orientalis C329.2. Evaluation of kinetic parameters for the synthesis of peptides and depsipeptides revealed a close relationship between VanA and DdlN in that depsipeptide formation was kinetically preferred at physiologic pH; however, the DdlN enzyme demonstrated a narrower substrate specificity and commensurately increased affinity for d-lactate in the C-terminal position over VanA. The results of these functional experiments also reinforce the results of previous studies that demonstrated that glycopeptide resistance enzymes from glycopeptide-producing bacteria are potential sources of resistance enzymes in clinically relevant bacteria. PMID:9791137

d-Ala-d-Ser VanN-Type Transferable Vancomycin Resistance in Enterococcus faecium▿

PubMed Central

Lebreton, François; Depardieu, Florence; Bourdon, Nancy; Fines-Guyon, Marguerite; Berger, Pierre; Camiade, Sabine; Leclercq, Roland; Courvalin, Patrice; Cattoir, Vincent

2011-01-01

Enterococcus faecium UCN71, isolated from a blood culture, was resistant to low levels of vancomycin (MIC, 16 μg/ml) but susceptible to teicoplanin (MIC, 0.5 μg/ml). No amplification was observed with primers specific for the previously described glycopeptide resistance ligase genes, but a PCR product corresponding to a gene called vanN was obtained using degenerate primers and was sequenced. The deduced VanN protein was related (65% identity) to the d-alanine:d-serine VanL ligase. The organization of the vanN gene cluster, determined using degenerate primers and by thermal asymmetric interlaced (TAIL)-PCR, was similar to that of the vanC operons. A single promoter upstream from the resistance operon was identified by rapid amplification of cDNA ends (RACE)-PCR. The presence of peptidoglycan precursors ending in d-serine and d,d-peptidase activities in the absence of vancomycin indicated constitutive expression of the resistance operon. VanN-type resistance was transferable by conjugation to E. faecium. This is the first report of transferable d-Ala-d-Ser-type resistance in E. faecium. PMID:21807981

Sodium sulfur electric vehicle battery engineering program final report, September 2, 1986--June 15, 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1993-06-01

In September 1986 a contract was signed between Chloride Silent Power Limited (CSPL) and Sandia National Laboratories (SNL) entitled ``Sodium Sulfur Electric Vehicle Battery Engineering Program``. The aim of the cost shared program was to advance the state of the art of sodium sulfur batteries for electric vehicle propulsion. Initially, the work statement was non-specific in regard to the vehicle to be used as the design and test platform. Under a separate contract with the DOE, Ford Motor Company was designing an advanced electric vehicle drive system. This program, called the ETX II, used a modified Aerostar van for itsmore » platform. In 1987, the ETX II vehicle was adopted for the purposes of this contract. This report details the development and testing of a series of battery designs and concepts which led to the testing, in the US, of three substantial battery deliverables.« less

Latest developments in the Advanced Photovoltaic Solar Array Program

NASA Technical Reports Server (NTRS)

Stella, Paul M.; Kurland, Richard M.

1990-01-01

In 1985, the Advanced Photovoltaic Solar Array (APSA) Program was established to demonstrate a producible array system with a specific power greater than 130 W/kg at a 10-kW (BOL) power level. The latest program phase completed fabrication and initial functional testing of a prototype wing representative of a full-scale 5-kW (BOL) wing (except truncated in length to about 1 kW), with weight characteristics that could meet the 130-W/kg (BOL) specific power goal using thin silicon solar cell modules and weight-efficient structural components. The wing configuration and key design details are reviewed, along with results from key component-level and wing-level tests. Projections for future enhancements that may be expected through the use of advanced solar cells and structural components are shown. Performance estimates are given for solar electric propulsion orbital transfer missions through the Van Allen radiation belts. The latest APSA program plans are presented.

Promoting Psychological Resilience in the U.S. Military

DTIC Science & Technology

2011-01-01

biometrics (e.g., cholesterol, blood sugar, body fat analysis, body mass index [BMI]), fitness, and weight management, among others. • HeartMath...Behavioral Science Division Training Program,” Training and Education in Professional Psychology, 2008. 2(2): pp. 67–74. #6 Van Vliet, K.J., “ Shame and...K.J., “ Shame and Resilience in Adulthood: A Grounded Theory Study,” Journal of Counseling Psychology, 2008. 55(2): pp. 233–245. #21 Bonanno, G.A

Ion Source Development for a Compact Proton Beam Writing System II

DTIC Science & Technology

2012-02-17

5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) Jeroen van Kan 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ...N/A 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) AOARD, UNIT 45002, APO, AP, 96338-5002 10. SPONSOR/MONITOR’S ACRONYM( S ) AOARD 11...SPONSOR/MONITOR’S REPORT NUMBER( S ) AOARD-114099 12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13

Child Abuse Prevention and Treatment in the 1990s. Keeping Old Promises, Meeting New Demands. Hearing before the Select Committee on Children, Youth, and Families. House of Representatives, One Hundred Second Congress, Second Session (Denver, CO, September 15, 1991).

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. House Select Committee on Children, Youth, and Families.

Testimony on the topic of child abuse prevention and treatment is presented in this document. After an opening statement by Representative Patricia Schroeder of Colorado, testimony and supplemental materials by these persons are included: (1) Marilyn Van Derbur, motivational lecturer, Denver, Colorado; (2) Barry Bennett, program manager,…

Pharmacy access to sterile syringes for injection drug users: attitudes of participants in a syringe exchange program.

PubMed

Junge, B; Vlahov, D; Riley, E; Huettner, S; Brown, M; Beilenson, P

1999-01-01

To examine attitudes of participants of a van-based syringe exchange program (SEP) toward the hypothetical prospect of pharmacy-based syringe access. One-time, cross-sectional survey. Baltimore, Maryland. 206 injection drug users who participate in the Baltimore SEP. Face-to-face interviews. Location preferred for obtaining syringes, drug and syringe use, past experience with pharmacies, and willingness to pay. The sample was 67% men, 95% African American, and 95% unemployed; mean age was 39.8 years. A total of 19% of respondents had bought syringes at a pharmacy during the prior six months. Some 37% reported having been turned down when asking for syringes at a pharmacy, most commonly due to lack of identification to prove diabetic status (50%). If legal restrictions were lifted, 92% of respondents would obtain syringes from pharmacies, and would be willing to pay a mean price of $0.80 (median = $1.00) per syringe. Women were more likely than men to report the intention to switch from van-based SEP to pharmacy (57% versus 38%, p = .045). If current legal restrictions were lifted, pharmacies would be a viable syringe source appealing particularly to women, suggesting gender-specific access issues that should be addressed. The per-syringe price that study participants would be willing to pay exceeds typical retail prices, suggesting that pharmacists could charge enough per syringe to recoup operational costs.

Resonance oscillations of nonreciprocal long-range van der Waals forces between atoms in electromagnetic fields

NASA Astrophysics Data System (ADS)

Sherkunov, Yury

2018-03-01

We study theoretically the van der Waals interaction between two atoms out of equilibrium with an isotropic electromagnetic field. We demonstrate that at large interatomic separations, the van der Waals forces are resonant, spatially oscillating, and nonreciprocal due to resonance absorption and emission of virtual photons. We suggest that the van der Waals forces can be controlled and manipulated by tuning the spectrum of artificially created random light.

Storings analyse Ten Behoeve van het Materieelverzorgingsplan (Failure Analysis for the Maintenance Plan)

DTIC Science & Technology

1990-05-01

oporachtnemer verwezen naar de ’Algemone Voorwaarden voor Onderzoeks- opdrachten TNO’. dan wet de betreflende terzake fijasen partlijen gesloten * 11 ...ixvulling van het onderhoudsschema 9 2.4 Invulling van het onderhoudsschema in de praktijk 14 2.5 Gonclusies 16 3 STORINGSANALYSES 18 3.1 ’Failure mode...nnfd- en subgroep (dit is een opdeling van bet systeem naar functioneel sanienhangende delen). Pa gina 9 - Het onderhoudsniveau waar jedere

Implication of Two-Coupled Differential Van der Pol Duffing Oscillator in Weak Signal Detection

NASA Astrophysics Data System (ADS)

Peng, Hang-hang; Xu, Xue-mei; Yang, Bing-chu; Yin, Lin-zi

2016-04-01

The principle of the Van der Pol Duffing oscillator for state transition and for determining critical value is described, which has been studied to indicate that the application of the Van der Pol Duffing oscillator in weak signal detection is feasible. On the basis of this principle, an improved two-coupled differential Van der Pol Duffing oscillator is proposed which can identify signals under any frequency and ameliorate signal-to-noise ratio (SNR). The analytical methods of the proposed model and the construction of the proposed oscillator are introduced in detail. Numerical experiments on the properties of the proposed oscillator compared with those of the Van der Pol Duffing oscillator are carried out. Our numerical simulations have confirmed the analytical treatment. The results demonstrate that this novel oscillator has better detection performance than the Van der Pol Duffing oscillator.

van Manen's method and reduction in a phenomenological hermeneutic study.

PubMed

Heinonen, Kristiina

2015-03-01

To describe van Manen's method and concept of reduction in a study that used a phenomenological hermeneutic approach. Nurse researchers have used van Manen's method in different ways. Participants' lifeworlds are described in depth, but descriptions of reduction have been brief. The literature and knowledge review and manual search of research articles. Databases Web Science, PubMed, CINAHL and PsycINFO, without applying a time period, to identify uses of van Manen's method. This paper shows how van Manen's method has been used in nursing research and gives some examples of van Manen's reduction. Reduction enables us to conduct in-depth phenomenological hermeneutic research and understand people's lifeworlds. As there are many variations in adapting reduction, it is complex and confusing. This paper contributes to the discussion of phenomenology, hermeneutic study and reduction. It opens up reduction as a method for researchers to exploit.

Scaling laws for van der Waals interactions in nanostructured materials.

PubMed

Gobre, Vivekanand V; Tkatchenko, Alexandre

2013-01-01

Van der Waals interactions have a fundamental role in biology, physics and chemistry, in particular in the self-assembly and the ensuing function of nanostructured materials. Here we utilize an efficient microscopic method to demonstrate that van der Waals interactions in nanomaterials act at distances greater than typically assumed, and can be characterized by different scaling laws depending on the dimensionality and size of the system. Specifically, we study the behaviour of van der Waals interactions in single-layer and multilayer graphene, fullerenes of varying size, single-wall carbon nanotubes and graphene nanoribbons. As a function of nanostructure size, the van der Waals coefficients follow unusual trends for all of the considered systems, and deviate significantly from the conventionally employed pairwise-additive picture. We propose that the peculiar van der Waals interactions in nanostructured materials could be exploited to control their self-assembly.

Under Connecticut Skies: Exploring 100 Years of Astronomy at Van Vleck Observatory in Middletown, Connecticut

NASA Astrophysics Data System (ADS)

Kilgard, Roy E.; Williams, Amrys; Erickson, Paul; Herbst, William; Redfield, Seth

2017-01-01

Under Connecticut Skies examines the history of astronomy at Van Vleck Observatory, located on the campus of Wesleyan University in Middletown, Connecticut. Since its dedication in June of 1916, Van Vleck has been an important site of astronomical research, teaching, and public outreach. Over a thousand visitors pass through the observatory each year, and regular public observing nights happen year-round in cooperation with the Astronomical Society of Greater Hartford. Our project explores the place-based nature of astronomical research, the scientific instruments, labor, and individuals that have connected places around the world in networks of observation, and the broader history of how observational astronomy has linked local people, amateur observers, professional astronomers, and the tools and objects that have facilitated their work under Connecticut’s skies over the past 100 years. Our research team has produced a historical exhibition to help commemorate the observatory’s centennial that opened to the public in May of 2016. Our work included collecting, documenting, and interpretting this history through objects, archival documents, oral histories, photographs, and more. The result is both a museum and a working history "laboratory" for use by student and professional researchers. In addition to the exhibit itself, we have engaged in new interpretive programs to help bring the history of astronomy to life. Future work will include digitization of documents and teaching slides, further collection of oral histories, and expanding the collection to the web for use by off-site researches.

Research Update: Fast and tunable nanoionics in vertically aligned nanostructured films

NASA Astrophysics Data System (ADS)

Lee, Shinbuhm; MacManus-Driscoll, Judith L.

2017-04-01

This review provides the design principles to develop new nanoionic applications using vertically aligned nanostructured (VAN) thin films, incorporating two phases which self-assemble in one film. Tunable nanoionics has attracted great attention for energy and device applications, such as ion batteries, solid oxide fuel cells, catalysts, memories, and neuromorphic devices. Among many proposed device architectures, VAN films have strong potential for nanoionic applications since they show enhanced ionic conductivity and tunability. Here, we will review the recent progress on state-of-the-art nanoionic applications, which have been realized by using VAN films. In many VAN systems made by the inclusion of an oxygen ionic insulator, it is found that ions flow through the vertical heterointerfaces. The observation is consistent with structural incompatibility at the vertical heteroepitaxial interfaces resulting in oxygen deficiency in one of the phases and hence to oxygen ion conducting pathways. In other VAN systems where one of the phases is an ionic conductor, ions flow much faster within the ionic conducting phase than within the corresponding plain film. The improved ionic conduction coincides with much improved crystallinity in the ionically conducting nanocolumnar phase, induced by use of the VAN structure. Furthermore, for both cases Joule heating effects induced by localized ionic current flow also play a role for enhanced ionic conductivity. Nanocolumn stoichiometry and strain are other important parameters for tuning ionic conductivity in VAN films. Finally, double-layered VAN film architectures are discussed from the perspective of stabilizing VAN structures which would be less stable and hence less perfect when grown on standard substrates.

Martin Van Buren National Historic Site transportation analysis report

DOT National Transportation Integrated Search

2010-10-01

The Volpe Transportation Systems Center (Volpe Center) is providing transportation support to Martin Van Buren National Historic Site's (NHS) first General Management Plan (GMP), which will be complete in 2010 or 2011. Currently, Martin Van Buren NHS...

The Dramatic Methods of Hans van Dam.

ERIC Educational Resources Information Center

van de Water, Manon

1994-01-01

Interprets for the American reader the untranslated dramatic methods of Hans van Dam, a leading drama theorist in the Netherlands. Discusses the functions of drama as a method, closed dramatic methods, open dramatic methods, and applying van Dam's methods. (SR)

78 FR 37270 - Qualification of Drivers; Exemption Applications; Vision

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-20

... (IA) Thomas M. Harris (MI) Paul M. Hinkson (TN) Ellie L. Murphree (AL) Michael P. Passmore (FL) Wendell S. Sehen (OH) Gary E. Valentine (OH) Kevin W. Van Arsdol (CO) Charles Van Dyke (WI) Harlon C. Van...

Toward an Operational Definition of Cross-Cultural Competence from the Literature

DTIC Science & Technology

2008-01-01

Journal of Applied Psychology, 73, 410-420. Mol, S. T., Born, M. P., Willemsen, M. E., & Van Der Molen , H. T. (2005). Predicting expatriate job...decision-making processes (Ang, Van Dyne, Koh, & Ng, 2004; Ang, Van Dyne, & Koh, 2007). Because the CQ has demonstrated validity and covers the...empirical foundation. U.S. Army Research Institute for the Behavioral and Social Sciences, Study Report 2008-1. Arlington, VA: ARI. Ang, S., Van Dyne, L

A Design Procedure for Minimizing Propeller-Induced Vibration in Hull Structural Elements.

DTIC Science & Technology

1979-09-01

Propeller," 12th International Towing Tank Conference, Rome, 1969. 46. Van Manen , J. D., "The Effect of Cavitation on the Interaction Be- tween Propeller...The wake, when determined in absence of the propeller, is called the nominal wake field. Van Oossanen [8) points out that it is becoming...wire anemometer and the laser-Doppler anomometer. These are discussed briefly in a paper by van Gent and van Oossanen [11. 4. Estimate Longitudinal

Who Do We Deploy for Psychological Operations: A Function Profile for TPT Members

DTIC Science & Technology

2008-01-01

doet onderzoek om de ontwikkeling v’an PSYOPS in Nederland te ondersteunen. Een eerste stap, in het goed voorbereiden en uitvoeren van PSYOPS is het...bezit. De focus van het huidige project ligt op de selectiemethode van mensen die PSYOPS functies gaan vervullen. Naast Nederland zijn er ook andere NAVO...deze interviews kwam naar voren dat verschillende landen kampen met dezelfde problemen als Nederland wat betreft de selectie van het PSYOPS personeel

Beslisbevoegdheden van de Uitgestegen Soldaat. Deel B: Verbetering van Situational Awareness Met Behulp van de Soldier Digital Assistant in een Gesimuleerde Omgeving (Authority and Responsbility of the Dismounted Soldier. Part B. Improving the Situational Awareness using the Soldier Digital Assistant in a Simulated Environment)

DTIC Science & Technology

2007-04-01

Dergelijke omngevingen zijn tot op heden vrijwel uitsluitend gebruikt voor training en onderwijs , maar slechts zeer sporadisch voor wetenschappelijk...Onderstaande instanties/personen ontvangen een volledig exemplaar van het rapport. 1 DMO/SC-DR&D standaard inclusief digitale versie bijgeleverd op cd

Militaire Toepassingen Van Adaptieve Optiek (Military Applications of Adaptive Optics)

DTIC Science & Technology

2006-09-01

dat op dit moment met de beschikbare theorie mogelijk is. Een ander interessant aspect is de mate waarin de turbulentie effecten het jam patroon...systemen In WEAG studie JP8. 11 is aangetoond dat in theorie adaptieve technieken een verbetering van de prestaties van een DIRCM systeem kunnen...Molenaar; Theorie van de laserscintillometer; TNO repot PHL 1978-16 (1978). TNO-rapport I TNO-DV 2006 A336 35/35 6 Ondertekening Den Haag, september 2006

Kwalificate/Classificatie van Explosieve Stoffen en Munitie. Rapport 2. Testontwikkeling (Qualification/Classification Explosive Materials and Munition. 2. Test Development)

DTIC Science & Technology

1992-11-01

beschermkap van het apparaat af te halen , waardoor bij een eventuele ontsteking het energetisch materiaal (al dan niet brandend) weg kan springen. Tevens...TNO-DefensieonderzoekPr TN TNO-rapport Kwalificatielclassificatie van explosieve stoffen ~ PML 1992-68 en munitief Rapport ]I: Testontwikkeling...rapport Kwalificatielclassificatie van explosieve stoffen PML 1992-68 en munitie Rapport f1: Testontwikkeling november 1992 ~~- ExorrIaar no:- 1ýMI

Practical Nurses' Lived Experience of Returning to School.

PubMed

Chachula, Kathryn; Smith, Mary; Hyndman, Kathryn

2018-05-25

The lived experience of licensed practical nurses (LPNs) pursuing Bachelor of Nursing (BN) education is not commonly studied in Canada. The aim was to understand the transition experience of LPNs who bridged into a BN program. Max van Manen's phenomenological methodology was used through use of a semistructured interview guide to explore the lived experience of LPNs who pursued baccalaureate nursing education. Five themes were found: seeking advancement; stepping back into the student role; juggling work, school, and family; struggling to be understood; and seeing things differently. LPN-to-BN students have a well-developed sense of identity as nurses. These students can benefit from a specifically designed, stand-alone bridge course to situate them within a BN program.

Serine and alanine racemase activities of VanT: a protein necessary for vancomycin resistance in Enterococcus gallinarum BM4174.

PubMed

Arias, C A; Weisner, J; Blackburn, J M; Reynolds, P E

2000-07-01

Vancomycin resistance in Enterococcus gallinarum results from the production of UDP-MurNAc-pentapeptide[D-Ser]. VanT, a membrane-bound serine racemase, is one of three proteins essential for this resistance. To investigate the selectivity of racemization of L-Ser or L-Ala by VanT, a strain of Escherichia coli TKL-10 that requires D-Ala for growth at 42 degrees C was used as host for transformation experiments using plasmids containing the full-length vanT from Ent. gallinarum or the alanine racemase gene (alr) of Bacillus stearothermophilus: both plasmids were able to complement E. coli TKL-10 at 42 degrees C. No alanine or serine racemase activities were detected in the host strain E. coli TKL-10 grown at 30, 34 or 37 degrees C. Serine and alanine racemase activities were found almost exclusively (96%) in the membrane fraction of E. coli TKL-10/pCA4(vanT): the alanine racemase activity of VanT was 14% of the serine racemase activity in both E. coli TKL-10/pCA4(vanT) and E. coli XL-1 Blue/pCA4(vanT). Alanine racemase activity was present mainly (95%) in the cytoplasmic fraction of E. coli TKL-10/pJW40(alr), with a trace (1.6%) of serine racemase activity. Additionally, DNA encoding the soluble domain of VanT was cloned and expressed in E. coli M15 as a His-tagged polypeptide and purified: this polypeptide also exhibited both serine and alanine racemase activities; the latter was approximately 18% of the serine racemase activity, similar to that of the full-length, membrane-bound enzyme. N-terminal sequencing of the purified His-tagged polypeptide revealed a single amino acid sequence, indicating that the formation of heterodimers between subunits of His-tagged C-VanT and endogenous alanine racemases from E. coli was unlikely. The authors conclude that the membrane-bound serine racemase VanT also has alanine racemase activity but is able to racemize serine more efficiently than alanine, and that the cytoplasmic domain is responsible for the racemase activity.

Acute kidney injury associated with concomitant vancomycin and piperacillin/tazobactam administration: a systematic review and meta-analysis.

PubMed

Chen, Xiao-Yu; Xu, Ri-Xiang; Zhou, Xin; Liu, Yang; Hu, Cheng-Yang; Xie, Xue-Feng

2018-05-11

As a tricyclic glycopeptide antibiotic used to treat acute infections, Vancomycin (VAN) is often administered with piperacillin/tazobactam (PT) to treat various infections in clinical practice. However, whether the combination of these two drugs, compared to VAN alone, can cause an increased risk of acute kidney injury (AKI) remains controversial. This study aims to identify the correlation between the development of AKI and the combined use of VAN and PT. We conducted a meta-analysis of eight observational cohort studies (a total of 10727 participants received VAN and PT versus VAN and other β-lactams). PubMed, Chinese Biological Medicine Database (CBM), China National Knowledge Infrastructure (CNKI) Database, Wan Fang Digital Periodicals Database (WFDP), and China Science Citation Database (CSCD) were searched through April 2017 using "vancomycin" and "piperacillin" and "tazobactam" as well as "acute kidney injury" or "acute renal failure" or "AKI" or "ARF" or "nephrotoxicity." Two reviewers extracted the data and assessed the risk of bias. A correlation was found between the development of AKI and concurrent use of VAN and PT compared with concomitant VAN and β-lactams (OR 1.57; 95% CI, 1.13-2.01; I 2  = 76.4%, p < 0.001). Similar findings were obtained in an analysis of studies comparing concurrent VAN and PT use with concurrent VAN and β-lactam (cefepime) use (OR 1.50; 95% CI, 1.07-1.93; I 2  = 80.5%, p < 0.001). Exclusion of fair-quality and low-quality articles did not change the results (OR 1.49; 95% CI, 1.06-1.92; I 2  = 84.1%, p < 0.001). Regarding β-lactam therapy in clinical practice, an elevated risk of AKI due to the combined use of VAN and PT should be considered.

Characterization and modelling of VanT: a novel, membrane-bound, serine racemase from vancomycin-resistant Enterococcus gallinarum BM4174.

PubMed

Arias, C A; Martín-Martinez, M; Blundell, T L; Arthur, M; Courvalin, P; Reynolds, P E

1999-03-01

Sequence determination of a region downstream from the vanXYc gene in Enterococcus gallinarum BM4174 revealed an open reading frame, designated vanT, that encodes a 698-amino-acid polypeptide with an amino-terminal domain containing 10 predicted transmembrane segments. The protein contained a highly conserved pyridoxal phosphate attachment site in the C-terminal domain, typical of alanine racemases. The protein was overexpressed in Escherichia coli, and serine racemase activity was detected in the membrane but not in the cytoplasmic fraction after centrifugation of sonicated cells, whereas alanine racemase activity was located almost exclusively in the cytoplasm. When the protein was overexpressed as a polypeptide lacking the predicted transmembrane domain, serine racemase activity was detected in the cytoplasm. The serine racemase activity was partially (64%) inhibited by D-cycloserine, whereas host alanine racemase activity was almost totally inhibited (97%). Serine racemase activity was also detected in membrane preparations of constitutively vancomycin-resistant E. gallinarum BM4174 but not in BM4175, in which insertional inactivation of the vanC-1 D-Ala:D-Ser ligase gene probably had a polar effect on expression of the vanXYc and vanT genes. Comparative modelling of the deduced C-terminal domain was based on the alignment of VanT with the Air alanine racemase from Bacillus stearothermophilus. The model revealed that almost all critical amino acids in the active site of Air were conserved in VanT, indicating that the C-terminal domain of VanT is likely to adopt a three-dimensional structure similar to that of Air and that the protein could exist as a dimer. These results indicate that the source of D-serine for peptidoglycan synthesis in vancomycin-resistant enterococci expressing the VanC phenotype involves racemization of L- to D-serine by a membrane-bound serine racemase.

Space Van system update

NASA Astrophysics Data System (ADS)

Cormier, Len

1992-07-01

The Space Van is a proposed commercial launch vehicle that is designed to carry 1150 kg to a space-station orbit for a price of $1,900,000 per flight in 1992 dollars. This price includes return on preoperational investment. Recurring costs are expected to be about $840,000 per flight. The Space Van is a fully reusable, assisted-single-stage-to orbit system. The most innovative new feature of the Space Van system is the assist-stage concept. The assist stage uses only airbreathing engines for vertical takeoff and vertical landing in the horizontal attitude and for launching the rocket-powered orbiter stage at mach 0.8 and an altitude of about 12 km. The primary version of the orbiter is designed for cargo-only without a crew. However, a passenger version of the Space Van should be able to carry a crew of two plus six passengers to a space-station orbit. Since the Space Van is nearly single-stage, performance to polar orbit drops off significantly. The cargo version should be capable of carrying 350 kg to a 400-km polar orbit. In the passenger version, the Space Van should be able to carry two crew members - or one crew member plus a passenger.

Critical lines for an unequal size of molecules in a binary gas-liquid mixture around the van Laar point using the combination of the Tompa model and the van der Waals equation.

PubMed

Gençaslan, Mustafa; Keskin, Mustafa

2012-02-14

We combine the modified Tompa model with the van der Waals equation to study critical lines for an unequal size of molecules in a binary gas-liquid mixture around the van Laar point. The van Laar point is coined by Meijer and it is the only point at which the mathematical double point curve is stable. It is the intersection of the tricritical point and the double critical end point. We calculate the critical lines as a function of χ(1) and χ(2), the density of type I molecules and the density of type II molecules for various values of the system parameters; hence the global phase diagrams are presented and discussed in the density-density plane. We also investigate the connectivity of critical lines at the van Laar point and its vicinity and discuss these connections according to the Scott and van Konynenburg classifications. It is also found that the critical lines and phase behavior are extremely sensitive to small modifications in the system parameters. © 2012 American Institute of Physics

Healthcare-associated infections: infection prevention and control within the Accreditation Canada Qmentum Program.

PubMed

Nicklin, Wendy; Greco, Paula; Mitchell, Jonathan I

2009-01-01

Gardam, Lemieux, Reason, van Dijk and Goel argue that healthcare-associated infections (HAIs) are "a pressing and imminent concern in the context of patient safety." Accreditation Canada supports the position taken by these authors. The prevention and control of two HAIs of great concern, methicillin-resistant Staphylococcus aureus and Clostridium difficile, are an integral part of the Accreditation Canada program. A coordinated approach to combating HAIs and developing a culture of infection prevention and control is necessary, one that involves front-line healthcare professionals, senior leadership, national and provincial partners and the public. Since 2005, Accreditation Canada has increasingly strengthened the accreditation program in this area through a number of new strategies, including enhanced standards, required organizational practices, performance measures and indicators and the introduction of education programs. Optimizing the value of accreditation through an integrative approach with organizations' quality improvement programs will contribute to effectively combating HAIs and developing a culture of infection prevention and control.

Nanotechnology-Enabled Optical Molecular Imaging of Breast Cancer

DTIC Science & Technology

2013-09-01

Jacobus J M van Der Hoeven, Elsken van Der Wall, Petra van Der Groep, Paul J van Diest, Emile F I Comans, Urvi Joshi, et al. 2002. “Biologic...Leigh G Seamon, William B Farrar, and Edward W Martin . 2008. “Novel perioperative imaging with 18F-FDG PET/CT and intraoperative 18F-FDG detection...www.springerlink.com/content/n752170246r84660/. Hall, Nathan C, Stephen P Povoski, Douglas A Murrey, Michael V Knopp, and Edward W Martin . 2007. “Combined

Submaximal Exercise Testing Treadmill and Floor Walking.

DTIC Science & Technology

1978-05-01

Amputations," Archives of Physical Medicine and Rehabilitation, 56:67-71, 1975. 36. van der Walt, W. H., and Wyndham, C. H,, "An Equation for...C. H., van Renaburg, A. J., Rogr, G. G., Greyson, J. S.. and van der Walt, V. H., "Walk or Jog for Health: I, The Energy Cost of Walking or Running at...G., Greyson, J. S., and van der Walt, V. H., "Walk or Jog for Health: II, Iatimating the Maximi Aerobic Capacity for Exercise,* South &frIca Kedical

A Representational Approach to Knowledge and Multiple Skill Levels for Broad Classes of Computer Generated Forces

DTIC Science & Technology

1997-12-01

that I’ll turn my attention to that computer game we’ve talked so much about... Dave Van Veldhuizen and Scott Brown (soon-to-be Drs. Van Veldhuizen and...Industry Training Systems Conference. 1988. 37. Van Veldhuizen , D. A. and L. J Hutson. "A Design Methodology for Domain Inde- pendent Computer...proposed by Van Veld- huizen and Hutson (37), extends the general architecture to support both a domain- independent approach to implementing CGFs and

REMOTE LAND MINE(FIELD) DETECTION. An Overview of Techniques (DETECTIE VAN LANDMIJNEN EN MIJNENVELDEN OP AFSTAND. Een Overzicht van de technieken),

DTIC Science & Technology

1994-09-01

titel DETECTIE VAN LANDMIJNEN EN MIJNENVELDEN OP AFSTAND, een overzicht van de technieken auteur (s) Drs. J.S. Groot, Ir. Y.H.L. Janssen datum september...functions based on set theory . The fundamental theory is developed in the sixties. This theory was applicable to binary images (black-and-white images...held at TNO-FEL. Various subjects related to fusion techniques: Dempster Shafer theory , Bayesian inference, Kalman filtering, fuzzy logic. [A15], [B4

Beta-catenin: A Potential Survival Marker of Breast Cancer Stem Cells

DTIC Science & Technology

2006-09-01

T. C., Alexander, C. M., Georges-Labouesse, E., Van der Neut , R., Kreidberg, J. A., Jones, C. J., Sonnenberg, A. and Streuli, C. H. (2001...de Lau, W., Oving, I., Hurlstone, A., van der Horn, K., Batlle, E., Coudreuse, D., Haramis, A. P., Tjon-Pon-Fong, M., Moerer, P., van den Born, M...Scherer, D. C., Willert, K., Hintz, L., Nusse, R. & Weissman, I. L. (2003) Nature 423, 409-14. 36. van de Wetering, M., Sancho, E., Verweij, C

DoD Electronic Data Interchange (EDI) Convention: ASC X12 Transaction Set 836 Contract Award (Version 003010)

DTIC Science & Technology

1993-01-01

upon designation of DoD Activity Address Code (DoDAAC) or other code coordinated with the value-added network (VAN). Mandatory ISA06 106 Interc.ange...coordinated with the value-added network (VAN). Non-DoD activities use identification code qualified by ISA05 and coordinated with the VAN. Mandatory...designation of DoD Activity Address Code (DoDAAC) or other code coordinated with the value-added network (VAN). Mandatory ISA08 107 Interchange Receiver

Definitie Rapport Taktisch LAN Demonstratie (Definition Report Tactical LAN Demonstration)

DTIC Science & Technology

1990-06-01

am deze sneiheid te halen . Hierover kan eon uitspraak warden gedaan, enerzijds na de ontwikkeling van het S-4 interface en anderzijds na berokeningen...90-A02 *2ma~D. Definitie rapport taktisch LAN Niels Ult deze urgave reai erorden verrnengvldigd er of openbaar genakt door MiddeI van druk. folokopre...microfrilm Of OP wetke arroere 00lze 000 00k. zonoe, O~u S vdorafgaanoe loestermeng van TNOHet ter inzage gen van het TNO-rapport Ing. R. J . C.14

Testbed Environment for Distributed Observation (testbed omgeving voor gedistribueerde waarneming)

DTIC Science & Technology

2006-05-01

het IP-adres en portnumnmer van de MID halen . Ook de naamn van de XML-file om de NID te beschrijven staat hierin vermeld (in dit geval ’CSD.xmId’) in...DeviceML beschrijving van de NID op te halen . Dit wordt gedaan door een TCP/IP verbinding op te zetten tussen de LUS en de NID (via de DeviceML port...vernisenigvuidigd! enlof openbaar gensaaki door middel van druk, fotokopie, microftinm of op welke andere wijze dan ook, zonder voorafgaande schrifielijke

Structural and Functional Adaptation of Vancomycin Resistance VanT Serine Racemases

PubMed Central

Meziane-Cherif, Djalal; Stogios, Peter J.; Evdokimova, Elena; Egorova, Olga

2015-01-01

ABSTRACT Vancomycin resistance in Gram-positive bacteria results from the replacement of the d-alanyl–d-alanine target of peptidoglycan precursors with d-alanyl–d-lactate or d-alanyl–d-serine (d-Ala-d-Ser), to which vancomycin has low binding affinity. VanT is one of the proteins required for the production of d-Ala-d-Ser-terminating precursors by converting l-Ser to d-Ser. VanT is composed of two domains, an N-terminal membrane-bound domain, likely involved in l-Ser uptake, and a C-terminal cytoplasmic catalytic domain which is related to bacterial alanine racemases. To gain insight into the molecular function of VanT, the crystal structure of the catalytic domain of VanTG from VanG-type resistant Enterococcus faecalis BM4518 was determined. The structure showed significant similarity to type III pyridoxal 5′-phosphate (PLP)-dependent alanine racemases, which are essential for peptidoglycan synthesis. Comparative structural analysis between VanTG and alanine racemases as well as site-directed mutagenesis identified three specific active site positions centered around Asn696 which are responsible for the l-amino acid specificity. This analysis also suggested that VanT racemases evolved from regular alanine racemases by acquiring additional selectivity toward serine while preserving that for alanine. The 4-fold-lower relative catalytic efficiency of VanTG against l-Ser versus l-Ala implied that this enzyme relies on its membrane-bound domain for l-Ser transport to increase the overall rate of d-Ser production. These findings illustrate how vancomycin pressure selected for molecular adaptation of a housekeeping enzyme to a bifunctional enzyme to allow for peptidoglycan remodeling, a strategy increasingly observed in antibiotic-resistant bacteria. PMID:26265719

Structural and functional adaptation of vancomycin resistance VanT serine racemases

DOE PAGES

Meziane-Cherif, Djalal; Stogios, Peter J.; Evdokimova, Elena; ...

2015-08-11

Vancomycin resistance in Gram-positive bacteria results from the replacement of the D-alanyl–D-alanine target of peptidoglycan precursors with D-alanyl–D-lactate or D-alanyl–D-serine (D-Ala-D-Ser), to which vancomycin has low binding affinity. VanT is one of the proteins required for the production of D-Ala-D-Ser-terminating precursors by converting L-Ser to D-Ser. VanT is composed of two domains, an N-terminal membrane-bound domain, likely involved in L-Ser uptake, and a C-terminal cytoplasmic catalytic domain which is related to bacterial alanine racemases. To gain insight into the molecular function of VanT, the crystal structure of the catalytic domain of VanT G from VanG-type resistant Enterococcus faecalis BM4518more » was determined. The structure showed significant similarity to type III pyridoxal 5'-phosphate (PLP)-dependent alanine racemases, which are essential for peptidoglycan synthesis. Comparative structural analysis between VanT G and alanine racemases as well as site-directed mutagenesis identified three specific active site positions centered around Asn 696 which are responsible for theL-amino acid specificity. This analysis also suggested that VanT racemases evolved from regular alanine racemases by acquiring additional selectivity toward serine while preserving that for alanine. The 4-fold-lower relative catalytic efficiency of VanT G against L-Ser versus L-Ala implied that this enzyme relies on its membrane-bound domain for L-Ser transport to increase the overall rate of D-Ser production. These findings illustrate how vancomycin pressure selected for molecular adaptation of a housekeeping enzyme to a bifunctional enzyme to allow for peptidoglycan remodeling, a strategy increasingly observed in antibiotic-resistant bacteria.« less

A discussion of the socio-economic losses and shelter impacts from the Van, Turkey Earthquakes of October and November 2011

NASA Astrophysics Data System (ADS)

Daniell, J. E.; Khazai, B.; Wenzel, F.; Kunz-Plapp, T.; Vervaeck, A.; Muehr, B.; Markus, M.

2012-04-01

The Van earthquake in 2011 hit at 10:41 GMT (13:41 Local) on Sunday, October 23rd, 2011. It was a Mw7.1-7.3 event located at a depth of around 10 km with the epicentre located directly between Ercis (pop. 75,000) and Van (pop. 370,000). Since then, the CEDIM Forensic Analysis Group (using a team of seismologists, engineers, sociologists and meteorologists) and www.earthquake-report.com has reported and analysed on the Van event. In addition, many damaging aftershocks occurring after the main eventwere analysed including a major aftershock centered in Van-Edremit on November 9th, 2011, causing much additional losses. The province of Van has around 1.035 million people as of the last census. The Van province is one of the poorest in Turkey and has much inequality between the rural and urban centers with an average HDI (Human Development Index) around that of Bhutan or Congo. The earthquakes are estimated to have caused 604 deaths (23 October) and 40 deaths (9 November); mostly due to falling debris and house collapse). In addition, between 1 billion TRY to 4 billion TRY (approx. 555 million USD - 2.2 billion USD) is estimated as total economic losses. This represents around 17 to 66% of the provincial GDP of the Van Province (approx. 3.3 billion USD) as of 2011. From the CATDAT Damaging Earthquakes Database, major earthquakes such as this one have occurred in the year 1111 causing major damage and having a magnitude around 6.5-7. In the year 1646 or 1648, Van was again struck by a M6.7 quake killing around 2000 people. In 1881, a M6.3 earthquake near Van killed 95 people. Again, in 1941, a M5.9 earthquake affected Ercis and Van killing between 190 and 430 people. 1945-1946 as well as 1972 brought again damaging and casualty-bearing earthquakes to the Van province. In 1976, the Van-Muradiye earthquake struck the border region with a M7, killing around 3840 people and causing around 51,000 people to become homeless. Key immediate lessons from similar historic earthquakes in eastern Turkey were developed in terms of the mass shelter and post-earthquake housing needs of the displaced population of Van. This included an analysis of shelter and reconstruction requirements under winter weather conditions; community resourcefulness in coping with housing needs through indigenous methods; and issues with in-place sheltering versus relocation and resettlement. A summary of the losses and implications on the GDP, economic dynamics, capital stock, social structure shelter and housing needs of the region is discussed. In addition, a quick comparison to past similar earthquakes is undertaken through the use of CATDAT.

Seismic Wave Attenuation and Yield Determination at Regional Distances

DTIC Science & Technology

1989-05-25

estimation, Bull. Seism. Soc. Am. 75, 379-390. Ervin, C. P. and L. D. McGinnis (1975). Reelfoot rift: Reactivated precursor to the Mis- sissippi...spectra in Friuli. Peng et al. (1987) where rl ranges between 1.06 and 1.33 in the Mammoth Lakes -Bishop area, van Eck (1988) where Q0 = 65 and q7 = 1.05...Bob Smith Department of Geophysics University of Utah 1400 East 2nd South Salt Lake City, UT 84112 Dr. S. W. Smith Geophysics Program University of

Structure-Based Design of Molecules to Reactivate Tumor-Derived p53 Mutations

DTIC Science & Technology

2006-06-01

fact, approximately half of the major forms of cancer contain p53 mutations, and the vast majority of these cluster in conserved regions or “hot...structures were subjected to 5.0 ns MD simulations using the program GROMACS 3.3 (Van Der Spoel et al., 2005). The RMSD values of backbone atoms from... analysis of residue-wise RMS fluctuations, shown in Figure 3B which shows that the stabilizing effect of Tris on the p53 core domain is distributed

Validation and Application of the ReaxFF Reactive Force Field to Hydrocarbon Oxidation Kinetics

DTIC Science & Technology

2016-06-23

AFRL-AFOSR-VA-TR-2016-0278 Validation and application of the ReaxFF reactive force field to hydrocarbon oxidation kinetics Adrianus Van Duin...application of the ReaxFF reactive force field to hydrocarbon oxidation kinetics 5a.  CONTRACT NUMBER 5b.  GRANT NUMBER FA9550-14-1-0355 5c.  PROGRAM...Chenoweth Dec14 Validation and application of the ReaxFF reactive force field to hydrocarbon oxidation kinetics DISTRIBUTION A: Distribution approved for

Analysing Operational Effects (Het analyseren van operationele effecten)

DTIC Science & Technology

2007-09-01

Programmanummer Projectnummer Datum V215 032.10 177 september 2007 Program maplanning Projectplanning Auteur (s)drs. M. Duistermaat Start 1 maart 2003 Start 1...called an effect, and when do we call it a task. In theory , an effect is formulated as ’to have accomplished a change in the situation’. and a task is...determining strategies for the mission. In the current chapter, we look at the different ways of utilization of the framework: in theory (the operational

Geluidsexpositie bij gebruik van CEP door F-16 crewchiefs (Sound Exposure Level of F-16 Crew Chiefs Using Communications Earplugs)

DTIC Science & Technology

2008-03-01

Communications Earplugs Auteur (s) dr. ir. M.M.J. Houben Programmanummer Projectnummer J.A. Verhave 032.13072 F.W.M. Geurtsen Rubricering rapport Program...de communicatie kiest men voor een geluidniveau dat luider is dan het waargenomen omgevingsgeluid. In theorie kan bet totale geluidsexpositieniveau...Afdelingshoofd Auteur TNO-rapport I TNO-DV 2008 A054 Bijlage A 1 1/3 A Simulatie Simulatie-omgeving Uit een opname gemaakt op Vhiegbasis Volkel hebben

Hierarchical Topological Network Analysis of Anatomical Human Brain Connectivity and Differences Related to Sex and Kinship

DTIC Science & Technology

2011-10-01

Richiardi, J., Eryilmaz, H., Schwartz, S ., Vuilleumier, P., Van De Ville, D.,1499 2010. Decoding brain states from fmri connectivity graphs. Neuroimage1500...Differences Related to Sex and Kinship 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER...5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) University of Minnesota,Institute for Mathematics and Its Applications,207

Results of SEI Independent Research and Development Projects and Report on Emerging Technologies and Technology Trends

DTIC Science & Technology

2004-10-01

Top-Level Process for Identification and Analysis of Safety-Related Re- quirements 4.4 Collaborators The primary SEI team members were Don Firesmith...Graff, M. & van Wyk, K. Secure Coding Principles & Practices. O’Reilly, 2003. • Hoglund, G. & McGraw, G. Exploiting Software: How to Break Code. Addison...Eisenecker, U.; Glück, R.; Vandevoorde, D.; & Veldhuizen , T. “Generative Programming and Active Libraries (Extended Abstract)” <osl.iu.edu/~tveldhui/papers

Computer Programs for Sun and Moon Illuminance with Contingent Tables and Diagrams

DTIC Science & Technology

1987-02-19

36 1930 215 /// /// 35 2012 154 /// /// 34 2109 125 /// /// 17 39 1903 229 /// III 38 1936 212 /// /// 37 2017 151 /// /// 36 2113 123 /// /// 35... Texarkana 122 38 Nape 105 39 Colorado Springs 91 36 TftfaWB 115 35 Needle« 107 41 Columbine 91 36 Tuekerman 122 38 Oakland 109 37 Cortez 94 35 Van...Christiansburg 96 33 Tarrall 112 40 Provo 77 37 Claramont 94 33 Texarkana 111 42 Randolph 80 38 Clifton Forge 99 33 Threekmorton 112 39 Richfield 82

MX Siting Investigation. Water Resources Program, Technical Summary Report. Volume I.

DTIC Science & Technology

1981-11-30

5. Garside and Schilling, 1979 6. Thordarson and Robinson, 1971 7. Rush and Everett, 1966 8. Rush and Eakin, 1963 9. Van Denburgh and Rush, 1974 10...both primary and secondary permeability of this unit is negligible. Winograd and Thordarson (1975) have reported transmissivities from rocks of this... Thordarson (1975) reported a transmissivity from formations in the Nevada Test Site equiv- alent to the lower half of this unit of 1470 ft2/day (136 m2/day

Conversion of Chemical Reaction Energy into Useful Work in the Van't Hoff Equilibrium Box

ERIC Educational Resources Information Center

Bazhin, N. M.; Parmon, V. N.

2007-01-01

The ideal van't Hoff equilibrium box is described in detail. It shows that van't Hoff equilibrium box divided in two parts can simultaneously produce heat and useful work without violation of the first law of thermodynamics.

Genetics Home Reference: van der Woude syndrome

MedlinePlus

... What is the prognosis of a genetic condition? Genetic and Rare Diseases Information Center Frequency Van der Woude syndrome is believed to occur in 1 in 35,000 to 1 in 100,000 people, based on data from Europe and Asia. Van der Woude syndrome ...

A New Method for Suppressing Periodic Narrowband Interference Based on the Chaotic van der Pol Oscillator

NASA Astrophysics Data System (ADS)

Lu, Jia; Zhang, Xiaoxing; Xiong, Hao

The chaotic van der Pol oscillator is a powerful tool for detecting defects in electric systems by using online partial discharge (PD) monitoring. This paper focuses on realizing weak PD signal detection in the strong periodic narrowband interference by using high sensitivity to the periodic narrowband interference signals and immunity to white noise and PD signals of chaotic systems. A new approach to removing the periodic narrowband interference by using a van der Pol chaotic oscillator is described by analyzing the motion characteristic of the chaotic oscillator on the basis of the van der Pol equation. Furthermore, the Floquet index for measuring the amplitude of periodic narrowband signals is redefined. The denoising signal processed by the chaotic van der Pol oscillators is further processed by wavelet analysis. Finally, the denoising results verify that the periodic narrowband and white noise interference can be removed efficiently by combining the theory of the chaotic van der Pol oscillator and wavelet analysis.

Van der Waals interaction in uniaxial anisotropic media.

PubMed

Kornilovitch, Pavel E

2013-01-23

Van der Waals interactions between flat surfaces in uniaxial anisotropic media are investigated in the nonretarded limit. The main focus is the effect of nonzero tilt between the optical axis and the surface normal on the strength of the van der Waals attraction. General expressions for the van der Waals free energy are derived using the surface mode method and the transfer-matrix formalism. To facilitate numerical calculations a temperature-dependent three-band parameterization of the dielectric tensor of the liquid crystal 5CB is developed. A solid slab immersed in a liquid crystal experiences a van der Waals torque that aligns the surface normal relative to the optical axis of the medium. The preferred orientation is different for different materials. Two solid slabs in close proximity experience a van der Waals attraction that is strongest for homeotropic alignment of the intervening liquid crystal for all the materials studied. The results have implications for the stability of plate-like colloids in liquid crystal hosts.

Van, Turkey Earthquake of 23 October 2011, Mw 7.2; An Overview on Disaster Management

PubMed Central

ZARÉ, Mehdi; NAZMAZAR, Behnaz

2013-01-01

An earthquake was happened on 23 October 2011 in Van, Turkey (Mw7.2) at the eastern most area of Anatolian plateau and in the neighborhood of Iranian border (West Azerbaijan Province). The study was performed based on field and office observations and has been focused on the process of disaster management in Turkey after the 23 October 2011 earthquake. We surveyed the quake from the view point of disaster management, and study the relief process during and after the catastrophe. The day-to-day disaster management procedure in seventeen days after the event has been scrutinized as well. The number of victims and extent of damage in Van earthquake was relatively limited according to the national experiences and recent modernization of infrastructures in Turkey. The Van earthquake caused 644 deaths and demolishing of several buildings in the cities of Van and Erciş in Van Province. The performance of the government organizations is however criticized based on their response to the event. PMID:23515082

Evolution of novel O-methyltransferases from the Vanilla planifolia caffeic acid O-methyltransferase.

PubMed

Li, Huaijun Michael; Rotter, David; Hartman, Thomas G; Pak, Fulya E; Havkin-Frenkel, Daphna; Belanger, Faith C

2006-06-01

The biosynthesis of many plant secondary compounds involves the methylation of one or more hydroxyl groups, catalyzed by O-methyltransferases (OMTs). Here, we report the characterization of two OMTs, Van OMT-2 and Van OMT-3, from the orchid Vanilla planifolia Andrews. These enzymes catalyze the methylation of a single outer hydroxyl group in substrates possessing a 1,2,3-trihydroxybenzene moiety, such as methyl gallate and myricetin. This is a substrate requirement not previously reported for any OMTs. Based on sequence analysis these enzymes are most similar to caffeic acid O-methyltransferases (COMTs), but they have negligible activity with typical COMT substrates. Seven of 12 conserved substrate-binding residues in COMTs are altered in Van OMT-2 and Van OMT-3. Phylogenetic analysis of the sequences suggests that Van OMT-2 and Van OMT-3 evolved from the V. planifolia COMT. These V. planifolia OMTs are new instances of COMT-like enzymes with novel substrate preferences.

Reply to “Statistical evaluation of the VAN Method using the historic earthquake catalog in Greece,” by Richard L. Aceves, Stephen K. Park and David J. Strauss

NASA Astrophysics Data System (ADS)

Varotsos, P.; Lazaridou, M.

The pioneering calculation by Aceves et al. [1996] shed light on the main question of this debate, i.e., on whether “VAN predictions can be ascribed to chance.” Aceves et al. [1996] conclude that “the VAN method has resulted in a significantly higher prediction rate than randomly sampling a PDF (probability density function) map generated from a 25 year history of earthquakes.” After investigating the totality of VAN predictions issued during the period 1987-1989, Aceves et al. [1996] found: “The prediction rate for the VAN method clearly exceeds that from the random model at all time lags between 5-22 days. At a 5 day time lag, the VAN prediction rate of 35.7% has a P-value of less than 0.06%. This means that a random model does as well as does the VAN method less than 0.06% of the time. At 22 days, the prediction rate of 67.9% has a P-value of less than 0.07%.” These conclusions basically coincide with those of Hamada [1993] although Aceves et al. [1996] followed different procedures. They are also in fundamental agreement with the results of Honkura and Tanaka [1996]. Another important conclusion of Aceves et al. [1996] is that, after declustering the earthquake catalog and prediction list from aftershocks, “VAN method is still formally significant.”

[Implementation of vanA and vanB genes by PCR technique research interest in system (Xpert vanA/vanB CepheidR) closed in a laboratory of microbiology in managing an outbreak to Enterococcus faecium resistant glycopeptide (EfRG)].

PubMed

Dekeyser, S; Beclin, E; Descamps, D

2011-04-01

The closed system PCR for the rapid detection of vanA and vanB genes (Xpert vanA/vanB Cepheid(®)) was evaluated in our laboratory, to improve the rapidity of the response and thus the management of patients and isolation measures during two GRE outbreaks. From March to December2009, 565 samples were analysed by PCR associated to bacterial culture initially for all samples for 2months (n = 75), and thereafter for PCR-positive samples only. In this study, sensitivity and negative predictive values of the PCR were 100%. Specificity was evaluated in the presence and absence of outbreak: 69.3 and 76.8% respectively. The variability of false positive rates between units were lower in nonepidemic than during epidemic phase. The global false positive rate was 23.9%. This easy-to-use technology provides rapid results… four samples are tested in 1h versus 72h for culture. Despite its reagent cost, it represents an important hospital diagnostic tool: improvement of the management of cohorting areas and patient transfer between units, adaptation of isolation measures and treatments. However, culture remains necessary to confirm any positive result obtained by PCR and for epidemiological surveillance. Copyright © 2010 Elsevier Masson SAS. All rights reserved.

Genetics Home Reference: Ellis-van Creveld syndrome

MedlinePlus

... CREVELD SYNDROME Sources for This Page Baujat G, Le Merrer M. Ellis-van Creveld syndrome. Orphanet J Rare Dis. 2007 Jun ... CB, Kochilas L, Schimmenti LA, Moller JH. Ellis-van Creveld syndrome and congenital heart defects: presentation of an additional 32 cases. Pediatr Cardiol. 2011 Oct;32( ...

Testing the dynamic rollover resistance of two 15-passenger vans with multiple load configurations

DOT National Transportation Integrated Search

2004-06-01

As a consequence of NTSB Safety Recommendations H-02-26 and H-02-28, NHTSA performed a study to investigate the effects different load conditions may have on the dynamic rollover resistance of 15-passenger vans. The two vans used in this study, a 200...

IKK and (Beta) - Catenin in Breast Cancer

DTIC Science & Technology

2004-07-01

signaling activity. Earlier data generated from the Byers lab have shown that phosphorylation of certain serine residues in the N-terminal of 13...ligand specificity. Cancer Res 60:4709-4713. 58. van de Wetering, M., R. Cavailo, D. Dooijes, M. van Beest , J. van Es, J. Louriero, A. Ypma, D. Hursh

Jao Van De Lagemaat | NREL

Science.gov Websites

Jao Van De Lagemaat Photo of Jao Vandelagemaat. Jao Van De Lagemaat Center Director: Chemistry and Lagemaat is currently the Center Director of the Chemistry and Nanoscience Center at NREL. He received his university. Education Ph.D. Physical Chemistry, University of Utrecht Featured Publications View all NREL

Is Progressive Education Obsolete: A Reconsideration.

ERIC Educational Resources Information Center

Beineke, John A.

1993-01-01

Van Til's 1962 article on whether or not progressive education is obsolete was a response to charges that the new education as espoused by Dewey was outmoded. This paper reexamines Van Til's article and suggests a prognostication similar to Van Til's could be ventured today that another period of progressivism is inevitable. (SM)

A Conversation with William Van Til.

ERIC Educational Resources Information Center

Beineke, John A.

1989-01-01

Reports an interview with William Van Til, Coffman Distinguished Professor Emeritus of Education at Indiana State University (Terre Haute). Van Til reviews his career as a social studies teacher and his writings on curriculum and social foundations. Presents his opinions on progressive education, famous educators, educational history and reform,…

Basic Research in Electronics (JSEP)

DTIC Science & Technology

1991-12-01

Single Crystal Growth Single crystals of Bi2Sr 2 CaCu2 O8 (BSCCO) have been prepared following the method of Mitzi , et al. [241. A mixture of oxides...P.C. van Son, H. van Kempen and P. Wyder, Phys. Rev. Lett., 50 2226 (1987). [24] D.B. Mitzi , L.W. Lombardo, A. Kapitulnik,/S.S. Laderman and R.D...Phys. Rev., 165 837 (1908). P.C. van Son, H. van Kempen and P. Wyder, Phys. Rev. Lett., 59 2228 (1987). D.B. Mitzi , L.W. Lombardo, A. Kapitulnik

Nanotechnology-Enabled Optical Molecular Imaging of Breast Cancer

DTIC Science & Technology

2012-07-01

Jacobus J M van Der Hoeven, Elsken van Der Wall, Petra van Der Groep, Paul J van Diest, Emile F I Comans, Urvi Joshi, et al. 2002. “Biologic correlates...William B Farrar, and Edward W Martin . 2008. “Novel perioperative imaging with 18F-FDG PET/CT and intraoperative 18F-FDG detection using a handheld gamma...n752170246r84660/. Hall, Nathan C, Stephen P Povoski, Douglas A Murrey, Michael V Knopp, and Edward W Martin . 2007. “Combined approach of perioperative 18F-FDG PET

Dynamical property analysis of fractionally damped van der pol oscillator and its application

NASA Astrophysics Data System (ADS)

Zhong, Qiuhui; Zhang, Chunrui

2012-01-01

In this paper, the fractionally damped van der pol equation was studied. Firstly, the fractionally damped van der pol equation was transformed into a set of integer order equations. Then the Lyapunov exponents diagram was given. Secondly, it was transformed into a set of fractional integral equations and solved by a predictor-corrector method. The time domain diagrams and phase trajectory were used to describe the dynamic behavior. Finally, the fractionally damped van der pol equation was used to detect a weak signal.

Investigation of Gene Expression Correlating With Centrosome Amplification in Development and Progression of Breast Cancer

DTIC Science & Technology

2004-09-01

M. A., Broerse, J. J., deVries, J. B., vandenBerg, K. K., Knaan, 33. Papa, D., Li, S. A. & Li, J. J. (2003) Mol. Carcinog. 38, 97-105. S. & van der ...Veer LI, Dai H, van de Vijver MJ, et al. Gene (n = 84). These data are similar to those of van de expression profiling predicts clinical outcome of...breast Vijver et al,"O who demonstrated a significant cancer. Nature 2002;415:530-536. correlation between outcome and expression of 70 10 van de Vijver

Bepaling Referentiewaarden voor Ergonomie en Warmtebelasting van Lichtgewicht Bommenpakken (Determination of Ergonomic and Thermal Load Tests and Assessment of Reference Values With Light Weight Bomb Disposal Suits)

DTIC Science & Technology

2008-05-01

bommenpakken kunnen geven bij bewegingen worden gemeten met de volgende bewegingbeperkingtests: sit-and-reach, stand-and-reach, abductie van de armen ...anteflexie van de armen en beperking van zicht. Bij de sit-and-reach test komt een eventuele belernmering bij het voorover buigen naar voren. De...proefpersoon zit op de grond met de benen en armen gestrekt naar voren. Daarbij wordt de afstand tussen de tenen en de vingers gemeten (figuur 4). Als het pak

A notable difference between ideal gas and infinite molar volume limit of van der Waals gas

NASA Astrophysics Data System (ADS)

Liu, Q. H.; Shen, Y.; Bai, R. L.; Wang, X.

2010-05-01

The van der Waals equation of state does not sufficiently represent a gas unless a thermodynamic potential with two proper and independent variables is simultaneously determined. The limiting procedures under which the behaviour of the van der Waals gas approaches that of an ideal gas are letting two van der Waals coefficients be zero rather than letting the molar volume become infinitely large; otherwise, the partial derivative of internal energy with respect to pressure at a fixed temperature does not vanish.

Trajectory Simulation Model for a Side- Thruster Guided MLRS-Type Vehicle

DTIC Science & Technology

1999-05-01

km halen . Voor de toekomst heeft men behoefte aan een dracht van ongeveer 60 km. Het is de doelstelling van opdracht A95KL410 om kennis en inzicht...G.M.H.J.L. Gadiot Datum mei 1999 Opdrachtnr. A95KL410 Rapportnr. PML 1998-A80 Figuur M.I.- Lancering van een M26-raket vanaf een MLRS ’launcher’. De...Koninklijke Nederlandse Landmacht (KL) heeft het ’Multiple Launcher Rocket System’ (MLRS) in gebruik. Met de huidige uitrusting kan men een dracht van 30

Geographical Information Extraction With Remote Sensing. Part I - Main Report.

DTIC Science & Technology

1998-08-01

Oude Waalsdorperweg 63 Date P0 Box 96864 2509 JG The Hague August 1998 The Netherlands Author(s) Phone +31 70 374 00 00 Dr A.C. van den Broek Fax +31 70...328 09 61 M. van Persie H.H.S. Noorbergen Dr G.J. Rijckenberg SSponsor HWO-COfHWO-KL N E R Project officer J. Rogge Affiliation KIN/IA - i All...Main report Auteur(s) Dr. A.C. van den Broek, Ir. M. van Persie, Ing. H.H.S. Noorberg~en, Dr. G.J. Rijkenberg Datum augustus 1998 Opdrachtnr

Kennislacunes op het gebied van wapens en munitie in OVG (Knowledge Gaps in the Area of Weapons and Munitions in MOUT)

DTIC Science & Technology

2008-12-01

Structuur 6 2.2 Inzetketen 8 2.3 Combinaties van W&M en doelen 9 2.4 Militaire activiteiten 10 3 De OVG context 11 4 Kennislacunes wapens en...Aanlal pagina’s Aantal bijlagen Ongerubriceerd drs. R.G.W. Gouweleeuw 7 november 2008 11 )eze mbricering \\N ijzigl mci) Ongerubriceerd...TNO-rapport | TNO-DV 2008 A436 9 /24 2.3 Combinaties van W&M en doelen In [2] is een overzicht opgesteld van zogenoemde ’force assets’ die tegen

Geautomatiseerde Verwerking van Militaire berichten Volgens ADatP-3 (Automated Processing of Military Messages According to ADatP-3)

DTIC Science & Technology

1992-06-01

ATCCIS beoogt juist dat te bereiken door te werken aan ecn informatie model en een data element dictionary. TNO-rapport Pagina 9 Binnen bet C2...en distributie 44 4.3.2 Interface met de gebruiker 45 4.3.3 Interface met dc operationcle database 46 TNO-rapport Pagina 11 4.3.3.1 Interpretatie...die bezig zijn met het ontwikkelen en implementeren van berichtformaten. Deel I van de publicatie bevat de beschrijving van FORMETS, delen 11 , I11 en

Jacobus Schroeder van der Kolk (1797-1862): his resistance against materialism.

PubMed

Eling, P

1998-07-01

Schroeder van der Kolk is regarded as the founder of Dutch psychiatry and neurology. This paper describes his vitalistic views on the relation between body and soul, as formulated by him in a series of lectures. These lectures were intended to counteract the materialistic tendencies of some of Schroeder van der Kolk's French and German contemporaries. It is argued that Schroeder van der Kolk can be regarded as the transition in Holland from the "Naturphilosophie" approach to the modern experimental approach in physiology. Copyright 1998 Academic Press.

J. H. Van Vleck and Magnetism at the University of Wisconsin: 1928 -1934

NASA Astrophysics Data System (ADS)

Huber, David

2011-03-01

In 1928, John Van Vleck returned to his alma mater to take a position in the Physics Department. Six years later he left to join the faculty of Harvard University. While Van Vleck was at Wisconsin, he began a series of theoretical studies that helped lay the foundation for the modern theory of magnetism in solids. In 1932 Van Vleck published his celebrated monograph, The Theory of Electric and Magnetic Susceptibilities, in which he made use of the new theory to explain the results of experimental studies in a variety of magnetic materials. In my talk, I will review the accomplishments of Van Vleck and his students during this period and also comment briefly on his notes for a second edition of the book.

Margaret Cavendish's materialist critique of van Helmontian chymistry.

PubMed

Clucas, Stephen

2011-03-01

A striking omission in the scholarship on the reception of the chymical philosophy of Jan Baptista van Helmont in England in the seventeenth century is the work of the mid-seventeenth-century natural philosopher Margaret Cavendish, Duchess of Newcastle. In her Philosophical Letters (1664), Cavendish offers an extended critique of Van Helmont's work (whose Ortus Medicince had recently been translated into English by John Sadler). In this paper, I compare Cavendish's criticisms with those of Robert Boyle in his Sceptical Chymist (1661). Both Boyle and Cavendish attacked Van Helmont for the obscurity of his chymical vocabulary and concepts, and attacked his seminalism. Although their critiques had much in common, they diverged in their attitudes to Van Helmont's experiments. As an opponent of the experimental philosophy, Cavendish had little interest in the quality of Van Helmont's experimental claims, whereas Boyle was critical of their unreplicability. I also try to show that the two writers had very different polemical agendas, with Boyle defending his vision of chymistry based on a corpuscularian natural philosophy, and Cavendish being as much concerned with establishing her religious orthodoxy as with defending the truth claims of her own materialist vitalism. For Cavendish, Van Helmont was an example of the dangers of mingling theology and natural philosophy.

Bayesian Multiscale Analysis of X-Ray Jet Features in High Redshift Quasars

NASA Astrophysics Data System (ADS)

McKeough, Kathryn; Siemiginowska, A.; Kashyap, V.; Stein, N.

2014-01-01

X-ray emission of powerful quasar jets may be a result of the inverse Compton (IC) process in which the Cosmic Microwave Background (CMB) photons gain energy by interactions with the jet’s relativistic electrons. However, there is no definite evidence that IC/CMB process is responsible for the observed X-ray emission of large scale jets. A step toward understanding the X-ray emission process is to study the Radio and X-ray morphologies of the jet. We implement a sophisticated Bayesian image analysis program, Low-count Image Reconstruction and Analysis (LIRA) (Esch et al. 2004; Conners & van Dyk 2007), to analyze jet features in 11 Chandra images of high redshift quasars (z ~ 2 - 4.8). Out of the 36 regions where knots are visible in the radio jets, nine showed detectable X-ray emission. We measured the ratios of the X-ray and radio luminosities of the detected features and found that they are consistent with the CMB radiation relationship. We derived a range of the bulk lorentz factor (Γ) for detected jet features under the CMB jet emission model. There is no discernible trend of Γ with redshift within the sample. The efficiency of the X-ray emission between the detected jet feature and the corresponding quasar also shows no correlation with redshift. This work is supported in part by the National Science Foundation REU and the Department of Defense ASSURE programs under NSF Grant no.1262851 and by the Smithsonian Institution, and by NASA Contract NAS8-39073 to the Chandra X-ray Center (CXC). This research has made use of data obtained from the Chandra Data Archive and Chandra Source Catalog, and software provided by the CXC in the application packages CIAO, ChIPS, and Sherpa. We thank Teddy Cheung for providing the VLA radio images. Connors, A., & van Dyk, D. A. 2007, Statistical Challenges in Modern Astronomy IV, 371, 101 Esch, D. N., Connors, A., Karovska, M., & van Dyk, D. A. 2004, ApJ, 610, 1213

Rankine-Hugoniot relationships for molecular crystal explosives calculated using density functional theory based molecular dynamics

NASA Astrophysics Data System (ADS)

Mattsson, Ann E.; Wixom, Ryan R.; Mattsson, Thomas R.

2011-06-01

Density Functional Theory (DFT) has become a crucial tool for understanding the behavior of matter. The ability to perform high-fidelity calculations is most important for cases where experiments are impossible, dangerous, and/or prohibitively expensive to perform. For molecular crystals, successful use of DFT has been hampered by an inability to correctly describe the van der Waals' dominated equilibrium state. We have explored a way of bypassing this problem by using the Armiento-Mattsson 2005 (AM05) exchange-correlation functional. This functional is highly accurate for a wide range of solids, in particular in compression. Another advantage is that AM05 does not include any van der Waals' attraction. We will demonstrate the method on the PETN Hugoniot, and discuss our confidence in the results and ongoing research aimed at improvement. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

Alfvén Wave Heating Model of an Active Region and Comparisons with the EIS Observations

NASA Astrophysics Data System (ADS)

Lawless, A. P.; Asgari-Targhi, M.

2013-12-01

We study the generation and dissipation of Alfvén waves in open and closed field lines using the images from the Solar Dynamics Observatory's (SDO) Atmospheric Imaging Assembly (AIA) (van Ballegouijen et al. 2011; Asgari-Targhi & van Ballegouijen 2012; Asgari et al. 2013). The goal is to search for observational evidence of Alfvén waves in the solar corona and to understand their role in coronal heating. We focus on one particular active region on the 10th of December 2007. Using the MDI magnetogram and the potential field modeling of this region, we create three-dimensional MHD models for several open and closed field lines in different locations in the active region. For each model, we compute the temperature, pressure, magnetic field strength, average heating rate, and other parameters along the loop. We then compare these results with the EIS observations. This research is supported by the NSF grant for the Solar physics REU Program at the Smithsonian Astrophysical Observatory (AGS-1263241) and contract SP02H1701R from Lockheed-Martin to SAO.

Modulation of surface flatness and van der Waals bonding of two-dimensional materials to reduce contact resistance.

NASA Astrophysics Data System (ADS)

Yue, Dewu; Yoo, Won Jong

Despite that the novel quantum mechanical properties of two-dimension (2D) materials are well explored theoretically, their electronic performance is limited by the contact resistance of the metallic interface and therefore their inherent novel properties are rarely realized experimentally. In this study, we demonstrate that we can largely reduce the contact resistance induced between metal and 2D materials, by controlling the surface condition of 2D materials, eg. surface flatness and van der Waals bonding. To induce the number of more effective carrier conducting modes, we engineer the surface roughness and dangling bonds of the 2D interface in contact with metal. As a result, electrical contact resistance of the metal interface is significantly reduced and carrier mobility in the device level is enhanced correspondingly. This work was supported by the Global Research Laboratory and Global Frontier R&D Programs at the Center for Hybrid Interface Materials, both funded by the Ministry of Science, ICT & Future Planning via the National Research Foundation of Korea (NRF).

Van Allen Discovery Most Important

NASA Technical Reports Server (NTRS)

Jastrow, R.

1959-01-01

The first step toward the exploration of space occurred approximately 22 months ago as a part of the International Geophysical Year. In the short interval since October, 1957, the new tools of research, the satellite and the space rocket, have produced two unexpected results of fundamental scientific importance. First, instruments placed in the Explorer satellites by James A. Van Allen have revealed the existence of layers of energetic particles in the outer atmosphere. This discovery constitutes the most significant research achievement of the IGY satellite program. The layers may provide the explanation for the aurora and other geophysical phenomena, and they will also influence the design of vehicles for manned space flight, whose occupants must be shielded against their harmful biological effects. Second, the shape of the earth has been determined very accurately with the aid of data from the first Vanguard. As a result of this investigation, we have found that our planet tends toward the shape of a pear, with its stem at the North Pole. This discovery may produce major changes in our ideas on the interior structure of the earth.

Application of galvanomagnetic measurements in temperature range 70-300 K to MBE GaAs layers characterization

NASA Astrophysics Data System (ADS)

Wolkenberg, Andrzej; Przeslawski, Tomasz

1996-04-01

Galvanomagnetic measurements were performed on the square shaped samples after Van der Pauw and on the Hall bar at low electric fields app. 1.5 V/cm and magnetic induction app. 6 kG in order to make a comparison between the theoretical and experimental results of the temperature dependence of mobility and resistivity from 70 K to 300 K. A calculation method was obtained of the drift mobility and the Hall mobility in which the scatterings are applied: on ionized impurities, on polar optical phonons, on acoustic phonons (deformation potential), on acoustic phonons (piezoelectric potential) and on dislocations. The elaborated method transformed to a computer program allows us to fit experimental values of the resistivity and the Hall mobility to those calculated. The fitting procedure makes it possible to characterize the quality of the n-type GaAs MBE layer, i.e. the net electron concentration, whole ionized impurities concentration and dislocation density after Read space charge cylinders model. The calculations together with the measurements allow us to obtain compensation ratio value in the layer, too. The influence of the epitaxial layer thickness on layers measurements accuracy in the case of Van der Pauw square probe was investigated. It was stated that in the layers under 3 micrometer the bulk properties are strongly influenced by both surfaces. The results of measurements of the same layer using the Van der Pauw and the Hall bar structure were compared. It was stated that the Hall bar structure only could be used to obtain proper measurements results.

An improved Rosetta pedotransfer function and evaluation in earth system models

NASA Astrophysics Data System (ADS)

Zhang, Y.; Schaap, M. G.

2017-12-01

Soil hydraulic parameters are often difficult and expensive to measure, leading to the pedotransfer functions (PTFs) an alternative to predict those parameters. Rosetta (Schaap et al., 2001, denoted as Rosetta1) are widely used PTFs, which is based on artificial neural network (ANN) analysis coupled with the bootstrap re-sampling method, allowing the estimation of van Genuchten water retention parameters (van Genuchten, 1980, abbreviated here as VG), saturated hydraulic conductivity (Ks), as well as their uncertainties. We present an improved hierarchical pedotransfer functions (Rosetta3) that unify the VG water retention and Ks submodels into one, thus allowing the estimation of uni-variate and bi-variate probability distributions of estimated parameters. Results show that the estimation bias of moisture content was reduced significantly. Rosetta1 and Posetta3 were implemented in the python programming language, and the source code are available online. Based on different soil water retention equations, there are diverse PTFs used in different disciplines of earth system modelings. PTFs based on Campbell [1974] or Clapp and Hornberger [1978] are frequently used in land surface models and general circulation models, while van Genuchten [1980] based PTFs are more widely used in hydrology and soil sciences. We use an independent global scale soil database to evaluate the performance of diverse PTFs used in different disciplines of earth system modelings. PTFs are evaluated based on different soil characteristics and environmental characteristics, such as soil textural data, soil organic carbon, soil pH, as well as precipitation and soil temperature. This analysis provides more quantitative estimation error information for PTF predictions in different disciplines of earth system modelings.

The liquid-vapor equilibria of TIP4P/2005 and BLYPSP-4F water models determined through direct simulations of the liquid-vapor interface.

PubMed

Hu, Hongyi; Wang, Feng

2015-06-07

In this paper, the surface tension and critical properties for the TIP4P/2005 and BLYPSP-4F models are reported. A clear dependence of surface tension on the van der Waals cutoff radius (rvdw) is shown when van der Waals interactions are modeled with a simple cutoff scheme. A linear extrapolation formula is proposed that can be used to determine the infinite rvdw surface tension through a few simulations with finite rvdw. A procedure for determining liquid and vapor densities is proposed that does not require fitting to a profile function. Although the critical temperature of water is also found to depend on the choice of rvdw, the dependence is weaker. We argue that a rvdw of 1.75 nm is a good compromise for water simulations when long-range van der Waals correction is not applied. Since the majority of computational programs do not support rigorous treatment of long-range dispersion, the establishment of a minimal acceptable rvdw is important for the simulation of a variety of inhomogeneous systems, such as water bubbles, and water in confined environments. The BLYPSP-4F model predicts room temperature surface tension marginally better than TIP4P/2005 but overestimates the critical temperature. This is expected since only liquid configurations were fit during the development of the BLYPSP-4F potential. The potential is expected to underestimate the stability of vapor and thus overestimate the region of stability for the liquid.

Water in Star-forming Regions with Herschel (WISH): recent results and trends

NASA Astrophysics Data System (ADS)

van Dishoeck, E. F.

2012-03-01

Water is a key molecule in the physics and chemistry of star- and planet-forming regions. In the `Water in Star-forming Regions with Herschel' (WISH) Key Program, we have obtained a comprehensive set of water data toward a large sample of well-characterized protostars, covering a wide range of masses and luminosities --from the lowest to the highest mass protostars--, as well as evolutionary stages --from pre-stellar cores to disks. Lines of both ortho- and para-H_2O and their isotopologues, as well as chemically related hydrides, are observed with the HIFI and PACS instruments. The data elucidate the physical processes responsible for the warm gas, probe dynamical processes associated with forming stars and planets (outflow, infall, expansion), test basic chemical processes and reveal the chemical evolution of water and the oxygen-reservoir into planet-forming disks. In this brief talk a few recent WISH highlights will be presented, including determinations of the water abundance in each of the different physical components (inner and outer envelope, outflow) and constraints on the ortho/para ratio. Special attention will be given to trends found across the sample, especially the similarity in profiles from low to high-mass protostars and the evolution of the gas-phase water abundance from prestellar cores to disks. More details can be found at http://www.strw.leidenuniv.nl/WISH, whereas overviews are given in van Dishoeck et al. (2011, PASP 123, 138), Kristensen & van Dishoeck (2011, Astronomische Nachrichten 332, 475) and Bergin & van Dishoeck (2012, Phil. Trans. Royal Soc. A).

It takes a village: a community partnership model in caring for the homeless.

PubMed

Zazworsky, Donna; Johnson, Nancy

2014-01-01

Population health management calls for hospitals and health care entities to better align their strategies in order to deliver quality care more efficiently. Although these efforts tend to be addressed with insured populations, the homeless demand a very intentional focus. The issue of homelessness has adverse effects on the health care system, resulting in the inefficient use of resources. Community-wide efforts must be mobilized to address this inefficiency and need for preventative care and self-management education for this population. Carondelet Health Network, in partnership with El Rio Community Health Center, a federally qualified health center, along with other health care and social service providers, has established the Southern Arizona Health Village for the Homeless, providing a health care delivery system to ensure the best functional and clinical outcomes. This system includes a van (the Van of Hope), licensed as a health center, and staffed with an El Rio Community Health Center nurse practitioner and a medical assistant partnering with a Carondelet Health Network behavioral health specialist and a community outreach worker. Clinical patient information is managed via an electronic health record inclusive of clinical data, number of visits, referrals, self-management education, hospitalizations, and follow-up care. A post-hospital program with shelters and an Emergency Room Navigation Program are additional components of the village that provide a comprehensive pre-acute and post-acute effort to support the homeless. Financial impact is measured by reductions in hospitalizations and average length of stay.

A. E. van Vogt: In Search of Meaning.

ERIC Educational Resources Information Center

Drake, H. L.

A general semantics perspective of science fiction writer A. E. van Vogt is presented in this paper. The first major section of the paper contains a biographical sketch of van Vogt and traces the influence of A. Korzybski's work on general semantics, "Science and Sanity," on his writing, while the second major section provides an…

Motion Sickness When Driving With a Head-Slaved Camera System

DTIC Science & Technology

2003-02-01

YPR-765 under armour (Report TM-97-A026). Soesterberg, The Netherlands: TNO Human Factors Research Institute. Van Erp, J.B.F., Padmos, P. & Tenkink, E...Institute. Van Erp, J.B.F., Van den Dobbelsteen, J.J. & Padmos, P. (1998). Improved camera-monitor system for driving YPR-765 under armour (Report TM-98

15 CFR Appendix F to Part 30 - FTR to FTSR Concordance

Code of Federal Regulations, 2014 CFR

2014-01-01

..., aircraft, cargo vans, and other carriers and containers 30.33 Vessels, planes, cargo vans, and other carriers and containers sold foreign. 30.27 Return of exported cargo to the United States prior to reaching... transactions. 30.26 Reporting of vessels, aircraft, cargo vans, and other carriers and containers 30.33 Vessels...

The "Discernment of a Human Face" in Research: A Reaction to Van Hesteren's Human Science and Counselling.

ERIC Educational Resources Information Center

Knowles, Don

1986-01-01

Responds to Van Hesteren's advocacy of a "human science" orientation, using constructs and analytical methods from phenomenology to enhance methodology. Approves of a philosophy of science and of a self-perspective. Questions the need for complex terminology, Van Hesteren's definition of what constitutes research, quantification, and…

A Diverging View of Role Modeling in Medical Education

ERIC Educational Resources Information Center

Sandhu, Gurjit; Rich, Jessica V.; Magas, Christopher; Walker, G. Ross

2015-01-01

Research in the area of role modeling has primarily focused on the qualities and attributes of exceptional role models, and less attention has been given to the act of role modeling itself (Elzubeir & Rizk, 2001; Jochemsen-van der Leeuw, van Dijk, van Etten-Jamaludin, & Wieringa-de Waard, 2013; Wright, 1996; Wright, Wong, & Newill,…

Fundacion Bernard van Leer, Boletin Informativo, 1987-1996 (Bernard van Leer Foundation Information Bulletin).

ERIC Educational Resources Information Center

Fundacion Bernard van Leer, Boletin Informativo, 1996

1996-01-01

This document consists of ten annual Spanish Language Bulletins, published during the period 1987-1996. The early bulletins were largely composed of selections originally published in the Bernard van Lear Foundation's English-Language "Newsletter The articles discuss topics such as: (1) parents as children's first teachers; (2) health and…

Early Childhood Matters: The Bulletin of the Bernard van Leer Foundation, 1999.

ERIC Educational Resources Information Center

Smale, Jim, Ed.

1999-01-01

This document consists of the three 1999 issues of The Bernard van Leer Foundation's "Early Childhood Matters." This periodical, addressed to practitioners in the field of early childhood education, evolved from an in-house publication directed to projects funded by the Bernard van Leer Foundation. Articles in the February 1999 edition…

Early Childhood Matters: The Bulletin of the Bernard van Leer Foundation, 1998.

ERIC Educational Resources Information Center

Smale, Jim, Ed.

1998-01-01

This document consists of the three 1998 issues of The Bernard van Leer Foundations'"Early Childhood Matters." This periodical, addressed to practitioners in the field of early childhood development, evolved from an in-house publication directed to projects funded by the Bernard van Leer Foundation. Articles in the February 1998 edition…

The Selection of a Van Lift or a Scooter.

ERIC Educational Resources Information Center

Stevens, John H.

1990-01-01

This newsletter issue describes 3-wheeled scooters and van lifts that can assist a person with a disability to drive independently or have access to transportation. The section on van lifts compares hydraulic lifts and electric lifts, lists manufacturers, and offers an "assessment quiz" outlining factors to consider in selecting a van…

Early Childhood Matters: The Bulletin of the Bernard van Leer Foundation, 2000.

ERIC Educational Resources Information Center

Smale, Jim, Ed.

2000-01-01

This document consists of the three 2000 issues of The Bernard van Leer Foundation's "Early Childhood Matters." This periodical, addressed to practitioners in the field of early childhood education, evolved from an in-house publication directed to projects funded by the Bernard van Leer Foundation. Articles in the February 2000 edition…

Genetics Home Reference: Langerhans cell histiocytosis

MedlinePlus

... Oct;29(5):853-73. doi: 10.1016/j.hoc.2015.06.005. Epub 2015 Aug 18. Review. Citation on PubMed Nelson DS, van Halteren A, Quispel WT, van den Bos C, Bovée JV, Patel B, Badalian-Very G, van Hummelen P, Ducar M, Lin L, MacConaill LE, Egeler RM, ...

Computer program for calculation of real gas turbulent boundary layers with variable edge entropy

NASA Technical Reports Server (NTRS)

Boney, L. R.

1974-01-01

A user's manual for a computer program which calculates real gas turbulent boundary layers with variable edge entropy on a blunt cone or flat plate at zero angle of attack is presented. An integral method is used. The method includes the effect of real gas in thermodynamic equilibrium and variable edge entropy. A modified Crocco enthalpy velocity relationship is used for the enthalpy profiles and an empirical correlation of the N-power law profile is used for the velocity profile. The skin-friction-coefficient expressions of Spalding and Chi and Van Driest are used in the solution of the momentum equation and in the heat-transfer predictions that use several modified forms of Reynolds analogy.

Billions to the poor for fuel bills, but not a penny for transportation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thero, S.

1980-05-17

Low-income persons are increasingly faced with having to choose between food and energy and are unable to afford adequate supplies of either. Government assistance to help the poor pay the higher costs has been legislated and funded, but critics find the government's program to be inadequate in scope, inappropriate, and unfair in the formula used to determine the funding levels of different regions. They also protest the absence of any help for transportation costs. The most popular solution to the transportation problem of the rural poor is federal aid for public transportation. A network of vans or old schoolbuses andmore » a program to rehabilitate old cars to make them more efficient are suggested. (DCK)« less

Cosmological models constructed by van der Waals fluid approximation and volumetric expansion

NASA Astrophysics Data System (ADS)

Samanta, G. C.; Myrzakulov, R.

The universe modeled with van der Waals fluid approximation, where the van der Waals fluid equation of state contains a single parameter ωv. Analytical solutions to the Einstein’s field equations are obtained by assuming the mean scale factor of the metric follows volumetric exponential and power-law expansions. The model describes a rapid expansion where the acceleration grows in an exponential way and the van der Waals fluid behaves like an inflation for an initial epoch of the universe. Also, the model describes that when time goes away the acceleration is positive, but it decreases to zero and the van der Waals fluid approximation behaves like a present accelerated phase of the universe. Finally, it is observed that the model contains a type-III future singularity for volumetric power-law expansion.

[Multidisciplinary treatment in orthodontics].

PubMed

Oosterkamp, B C M; Kuijpers, M A R

2015-11-01

In deze editie van het NTvT neemt het thema ‘Multidisciplinaire aanpak in de orthodontie’ de lezer mee in de mogelijkheden van multidisciplinaire zorg vanuit een orthodontisch oogpunt. Tandheelkunde is niet meer uitsluitend gericht op preventie en behandeling van cariës. De gebitstoestand van zowel ­kinderen als volwassenen is de afgelopen 30 jaar namelijk sterk verbeterd. De cariës­ervaring is duidelijk afgenomen en mensen behouden steeds langer hun natuurlijke gebit. Daarnaast is een fraai uitziend en goed functionerend gebit steeds vanzelfsprekender geworden en zijn patiënten gemotiveerd hun gebit te behouden. Deze ontwikkelingen vragen ook van (mond)zorgverleners een andere kijk op de zorg. De tandheelkundige zorg betreft steeds meer integrale zorg met een multidisciplinair karakter waarbij ­verschillende disciplines samenwerken om in samenspraak met de patiënt tot een optimaal resultaat te komen.

Enhanced Chiral Discriminatory van der Waals Interactions Mediated by Chiral Surfaces

NASA Astrophysics Data System (ADS)

Barcellona, Pablo; Safari, Hassan; Salam, A.; Buhmann, Stefan Yoshi

2017-05-01

We predict a discriminatory interaction between a chiral molecule and an achiral molecule which is mediated by a chiral body. To achieve this, we generalize the van der Waals interaction potential between two ground-state molecules with electric, magnetic, and chiral response to nontrivial environments. The force is evaluated using second-order perturbation theory with an effective Hamiltonian. Chiral media enhance or reduce the free interaction via many-body interactions, making it possible to measure the chiral contributions to the van der Waals force with current technology. The van der Waals interaction is discriminatory with respect to enantiomers of different handedness and could be used to separate enantiomers. We also suggest a specific geometric configuration where the electric contribution to the van der Waals interaction is zero, making the chiral component the dominant effect.

Voltage and Pressure Scaling of Streamer Dynamics in a Helium Plasma Jet With N2 CO-Flow (Postprint)

DTIC Science & Technology

2014-08-14

de Wetering, R. Blanc, E. M. van Veldhuizen , and U. Ebert, J. Phys. D: Appl. Phys. 43, 145204 (2010). 26T. M. P. Briels, J. Kos, G. J. J. Winands, E. M... van Veldhuizen , and U. Ebert, J. Phys. D: Appl. Phys. 41, 234004 (2008). 27See http://physics.nist.gov/PhysRefData/ASD for National Institute of...T. Briels, and E. van Velduizen, J. Geophys. Res. 115, A00E43, doi:10.1029/2009JA014867 (2010) and references therein. 25S. Nijdam, F. M. J. H. van

Quantum synchronization of quantum van der Pol oscillators with trapped ions.

PubMed

Lee, Tony E; Sadeghpour, H R

2013-12-06

The van der Pol oscillator is the prototypical self-sustained oscillator and has been used to model nonlinear behavior in biological and other classical processes. We investigate how quantum fluctuations affect phase locking of one or many van der Pol oscillators. We find that phase locking is much more robust in the quantum model than in the equivalent classical model. Trapped-ion experiments are ideally suited to simulate van der Pol oscillators in the quantum regime via sideband heating and cooling of motional modes. We provide realistic experimental parameters for 171Yb+ achievable with current technology.

Size Effects in Epitaxial Films of Magnetite

DTIC Science & Technology

2002-06-03

van Eemeren , J. aan de Stegge, 1727. WJ.M. de Jonge, Surf. Sci. 373 (1997) 85. [38] J.L. Dormann, T. Merceron, P. Renaudin, VA.M. Brabers, J. [20] S.A...Metals and Semiconductors, Trans Tech, Switzerland, 1994, p. __221. [4] G.A. Prinz, Phys. Today 48 (1995) 58. 100 - [5] P.J. van der Zaag. P.J.H...Bloemen. J.M. Gaines, R.M. Wolf, -10 -8 -6 -4 -2 0 2 4 6 8 10 P.A.A. van der Heijden, R.J.M. van de Veerdonk, W.J.M. velocity [mm/s] de Jonge, J. Magn. Magn

Vehicle test report: Jet Industries Electra Van 600

NASA Technical Reports Server (NTRS)

Price, T. W.; Wirth, V. A., Jr.

1982-01-01

The Electra Van 600, an electric vehicle, was tested. Tests were performed to characterize parameters of the Electra Van 600 and to provide baseline data to be used for comparison of improved batteries and to which will be incorporated into the vehicle. The vehicle tests concentrated on the electrical drive subsystem, the batteries, controller, and motor; coastdowns to characterize the road load and range evaluation for cyclic and constant speed conditions; and qualitative performance was evaluated. It is found that the Electra Van 600 range performance is approximately equal to the majority of the vehicles tested previously.

Energy Sources for Soldier Modernisation Programme Systems (Overzicht van Ontwikkelingen op het Gebied van Draagbare Energieopslag en Energieopwekking)

DTIC Science & Technology

1999-12-01

9 . http://home.earthlink.net/-fradella/homepage.htm 10. http ://web.mit.edu/aeroastro/www/labs/GTL/research/micro/micro.html 11 . http://www.ecr.co.il...Meijer 7 LAS/DB&P/BO/OB&T taxv. aooi Jansen 8 LAS/DB&PIBO/OB 9 LAS/DB&P/BO/CIV 10 OGMAN/Externe plannen Infanterie 11 DM/C31 12 DM/COM 13 KPU-bedrijf 14...detailed specifications mentioned before. TNO-rapport TNO-MEP - R 99/490 9 van 51 Samenvatting In dit rapport wordt een eerste globale selectie gemaakt: van

Structural and Functional Adaptation of Vancomycin Resistance VanT Serine Racemases.

PubMed

Meziane-Cherif, Djalal; Stogios, Peter J; Evdokimova, Elena; Egorova, Olga; Savchenko, Alexei; Courvalin, Patrice

2015-08-11

Vancomycin resistance in Gram-positive bacteria results from the replacement of the D-alanyl-D-alanine target of peptidoglycan precursors with D-alanyl-D-lactate or D-alanyl-D-serine (D-Ala-D-Ser), to which vancomycin has low binding affinity. VanT is one of the proteins required for the production of D-Ala-D-Ser-terminating precursors by converting L-Ser to D-Ser. VanT is composed of two domains, an N-terminal membrane-bound domain, likely involved in L-Ser uptake, and a C-terminal cytoplasmic catalytic domain which is related to bacterial alanine racemases. To gain insight into the molecular function of VanT, the crystal structure of the catalytic domain of VanTG from VanG-type resistant Enterococcus faecalis BM4518 was determined. The structure showed significant similarity to type III pyridoxal 5'-phosphate (PLP)-dependent alanine racemases, which are essential for peptidoglycan synthesis. Comparative structural analysis between VanTG and alanine racemases as well as site-directed mutagenesis identified three specific active site positions centered around Asn696 which are responsible for the L-amino acid specificity. This analysis also suggested that VanT racemases evolved from regular alanine racemases by acquiring additional selectivity toward serine while preserving that for alanine. The 4-fold-lower relative catalytic efficiency of VanTG against L-Ser versus L-Ala implied that this enzyme relies on its membrane-bound domain for L-Ser transport to increase the overall rate of d-Ser production. These findings illustrate how vancomycin pressure selected for molecular adaptation of a housekeeping enzyme to a bifunctional enzyme to allow for peptidoglycan remodeling, a strategy increasingly observed in antibiotic-resistant bacteria. Vancomycin is one of the drugs of last resort against Gram-positive antibiotic-resistant pathogens. However, bacteria have evolved a sophisticated mechanism which remodels the drug target, the D-alanine ending precursors in cell wall synthesis, into precursors terminating with D-lactate or D-serine, to which vancomycin has less affinity. D-Ser is synthesized by VanT serine racemase, which has two unusual characteristics: (i) it is one of the few serine racemases identified in bacteria and (ii) it contains a membrane-bound domain involved in L-Ser uptake. The structure of the catalytic domain of VanTG showed high similarity to alanine racemases, and we identified three specific active site substitutions responsible for L-Ser specificity. The data provide the molecular basis for VanT evolution to a bifunctional enzyme coordinating both transport and racemization. Our findings also illustrate the evolution of the essential alanine racemase into a vancomycin resistance enzyme in response to antibiotic pressure. Copyright © 2015 Meziane-Cherif et al.

Particle Energization in Earth's Van Allen Radiation Belts Due to Solar Wind Forcing

NASA Astrophysics Data System (ADS)

Baker, D. N.

2017-12-01

Early observations of the Earth's radiation environment clearly indicated that the Van Allen belts could be delineated into an inner zone dominated by high-energy protons and an outer zone dominated by high-energy electrons. The energy distribution, spatial extent and particle species makeup of the Van Allen belts has been subsequently explored by several space missions. However, recent observations by the NASA dual-spacecraft Van Allen Probes mission have revealed unexpected properties of the radiation belts, especially for electrons at highly relativistic (E > 2 MeV) and ultra-relativistic (E > 5 MeV) kinetic energies. In this presentation we show using high spatial and temporal resolution data from the experiments on board the Van Allen Probes that multiple belts can exist concurrently and that an exceedingly sharp inner boundary exists for ultra-relativistic electrons. Using additionally available Van Allen Probes data, we demonstrate that these remarkable features of energetic electrons are driven by strong solar and solar wind forcings. The comprehensive Van Allen Probes data show more broadly and in many ways how extremely high energy particles are accelerated, transported, and lost in the magnetosphere due to interplanetary shock wave interactions, coronal mass ejection impacts, and high-speed solar wind streams. The new data have shown especially how dayside processes play a key role in electron acceleration and loss processes.

Influence of van der Waals forces on increasing the strength and toughness in dynamic fracture of nanofibre networks: a peridynamic approach

NASA Astrophysics Data System (ADS)

Bobaru, F.

2007-07-01

The peridynamic method is used here to analyse the effect of van der Waals forces on the mechanical behaviour and strength and toughness properties of three-dimensional nanofibre networks under imposed stretch deformation. The peridynamic formulation allows for a natural inclusion of long-range forces (such as van der Waals forces) by considering all interactions as 'long-range'. We use van der Waals interactions only between different fibres and do not need to model individual atoms. Fracture is introduced at the microstructural (peridynamic bond) level for the microelastic type bonds, while van der Waals bonds can reform at any time. We conduct statistical studies to determine a certain volume element for which the network of randomly oriented fibres becomes quasi-isotropic and insensitive to statistical variations. This qualitative study shows that the presence of van der Waals interactions and of heterogeneities (sacrificial bonds) in the strength of the bonds at the crosslinks between fibres can help in increasing the strength and toughness of the nanofibre network. Two main mechanisms appear to control the deformation of nanofibre networks: fibre reorientation (caused by deformation and breakage) and fibre accretion (due to van der Waals interaction). Similarities to the observed toughness of polymer adhesive in the abalone shell composition are explained. The author would like to dedicate this work to the 60th anniversary of Professor Subrata Mukherjee.

Modified Van der Waals equation and law of corresponding states

NASA Astrophysics Data System (ADS)

Zhong, Wei; Xiao, Changming; Zhu, Yongkai

2017-04-01

It is well known that the Van der Waals equation is a modification of the ideal gas law, yet it can be used to describe both gas and liquid, and some important messages can be obtained from this state equation. However, the Van der Waals equation is not a precise state equation, and it does not give a good description of the law of corresponding states. In this paper, we expand the Van der Waals equation into its Taylor's series form, and then modify the fourth order expansion by changing the constant Virial coefficients into their analogous ones. Via this way, a more precise result about the law of corresponding states has been obtained, and the law of corresponding states can then be expressed as: in terms of the reduced variables, all fluids should obey the same equation with the analogous Virial coefficients. In addition, the system of 3 He with quantum effects has also been taken into consideration with our modified Van der Waals equation, and it is found that, for a normal system without quantum effect, the modification on ideal gas law from the Van der Waals equation is more significant than the real case, however, for a system with quantum effect, this modification is less significant than the real case, thus a factor is introduced in this paper to weaken or strengthen the modification of the Van der Waals equation, respectively.

Arnoldus Van Rhijn on aphasia: a forgotten thesis.

PubMed

Eling, Paul

2011-01-01

Aphasia formed a central topic in the discussion on localization of function in the nineteenth century, in particular in France, Germany and Great Brittain. Little is known on contributions from the Netherlands. This paper aims to discuss the contents of Arnoldus Van Rhijn's dissertation on aphasia, written in 1868 and one of the very few Dutch contributions to aphasiology in the nineteenth century. Added to this paper is a translation of the "Physiological Part" of Van Rhijn's dissertation. Van Rhijn discussed three cases with acquired aphasia. He rejected Broca's notion of a cortical center for the articulation of speech and instead regarded the cortex as the site where the will exerted its influence. He argued that there is a certain form of specialization: the will to say something is localized at a different place than the will to write. According to Van Rhijn, the highest motor centers are localized in the subcortical gray areas. Van Rhijn concluded that aphasia may result from lesions to the cortical centers involved in speaking, or from a disconnection of the cortical and subcortical centers. Very little work was done on aphasia in the 19th century in the Netherlands. Van Rhijn's thesis, from an aphasiological point of view of limited value, does show that the notions of "centers", "connections", and "disorders due to disconnections" were generally known before Wernicke, also in the Netherlands. Copyright © 2011 Elsevier Srl. All rights reserved.

Effectiveness of a Mobile Mammography Program.

PubMed

Stanley, Elizabeth; Lewis, Madelene C; Irshad, Abid; Ackerman, Susan; Collins, Heather; Pavic, Dag; Leddy, Rebecca J

2017-12-01

Mobile mammography units have increasingly been used to address patient health care disparities; however, there are limited data comparing mobile units to stationary sites. This study aims to evaluate the characteristics of women who underwent mammography screening in a mobile unit versus those who underwent mammography screening at a cancer center. In this retrospective study, we analyzed all screening mammography examinations performed in a mobile unit in 2014 (n = 1433 examinations). For comparison, we randomized and reviewed an equivalent number of screening mammography examinations performed at our cancer center in 2014 (n = 1434 examinations). BI-RADS assessment, adherence to follow-up, biopsies performed, cancer detection rate, and sociodemographic variables were recorded. An independent-samples t test was conducted to identify potential differences in age between cancer center patients and mobile unit patients. Chi-square analyses were used to test for associations between location and factors such as health insurance, race, marital status, geographic area, adherence to screening guidelines, recall rate, adherence to follow-up, and cancer detection rates. Patients visiting our cancer center (mean = 57.74 years; SD = 10.55) were significantly older than those visiting the mobile unit (mean = 52.58 years; SD = 8.19; p < 0.001). There was a significant association between location and health insurance status (χ 2 = 610.92; p < 0.001) with more uninsured patients undergoing screening in the mobile van (cancer center = 3.70%, mobile unit = 38.73%). There was a significant association between screening location and patient race (χ 2 = 118.75, p < 0.001), with more white patients being screened at the cancer center (cancer center = 47.28%, mobile unit = 33.30%), more black patients being screened in the mobile van (cancer center = 49.30%, mobile unit = 54.15%), and more Hispanic patients being screened in the mobile van (cancer center = 1.05%, mobile unit = 6.77%). There was a significant association between location and patient marital status (χ 2 = 135.61, p < 0.001), with more married patients screened at the cancer center (cancer center = 49.16%, mobile unit = 38.31%), more single patients screened in the mobile van (cancer center = 25.17%, mobile unit = 34.47%), and more widowed patients being screened at the cancer center (cancer center = 8.09%, mobile unit = 4.47%). There was a significant association between location and geographic area (χ 2 = 33.33, p < 0.001), with both locations reaching more urban than rural patients (cancer center = 79.99%, mobile unit = 70.62%). There was a significant association between location and adherence to screening guidelines (χ 2 = 179.60, p < 0.001), with patients screened at the cancer center being more compliant (cancer center = 56.90%, mobile unit = 34.47%). Finally, there was a significant association between location and recall rate (χ 2 = 4.06, p < 0.001). The cancer center had a lower recall rate (13.32%) than the mobile van (15.98%). Of those patients with BI-RADS 0, there was a significant association between location and adherence to follow-up (χ 2 = 22.75, p < 0.001) with patients using the mobile unit less likely to return for additional imaging (cancer center = 2.65%, mobile unit = 17.03%). Significant differences were found among patients visiting the cancer center versus the mobile mammography van. The cancer center's population is older and more adherent to guidelines, whereas the mobile mammography population exhibited greater racial and marital diversity, higher recall rate, and lack of adherence to follow-up recommendations. By identifying these characteristics, we can develop programs and materials that meet these populations' needs and behaviors, ultimately increasing mammography screening and follow-up rates among underserved populations.

Mrs. Chandrasekhar addresses the media in TRW Media Hospitality Tent

NASA Technical Reports Server (NTRS)

1999-01-01

Mrs. Lalitha Chandrasekhar (at podium), wife of the late Indian- American Nobel Laureate Subrahmanyan Chandrasekhar, addresses the media and other invited guests in the TRW Media Hospitality Tent at the NASA Press Site at KSC. Other participants in the program (seated facing the audience, left to right) are the winners of the contest to rename the telescope, Jatila van der Veen, academic coordinator and lecturer, Physics Dept., University of Santa Barbara, Calif., and Tyrel Johnson, high school student, Laclede, Idaho; Joanne Maguire, vice-president and general manager, TRW Space & Laser Programs Division; and Dr. Alan Bunner, Science Program Director, Structure and Evolution of the Universe, Office of Space Science, NASA Headquarters, Washington, D.C. The name 'Chandra,' a shortened version of Chandrasekhar, was the name the Nobel Laureate preferred among friends and colleagues. 'Chandra' also means 'Moon' or 'luminous' in Sanskrit. The observatory is scheduled to be launched aboard Columbia on Space Shuttle mission STS-93.

KSC-99pp0978

NASA Image and Video Library

1999-07-19

Mrs. Lalitha Chandrasekhar (at podium), wife of the late Indian-American Nobel Laureate Subrahmanyan Chandrasekhar, addresses the media and other invited guests in the TRW Media Hospitality Tent at the NASA Press Site at KSC. Other participants in the program (seated facing the audience, left to right) are the winners of the contest to rename the telescope, Jatila van der Veen, academic coordinator and lecturer, Physics Dept., University of Santa Barbara, Calif., and Tyrel Johnson, high school student, Laclede, Idaho; Joanne Maguire, vice-president and general manager, TRW Space & Laser Programs Division; and Dr. Alan Bunner, Science Program Director, Structure and Evolution of the Universe, Office of Space Science, NASA Headquarters, Washington, D.C. The name "Chandra," a shortened version of Chandrasekhar, was the name the Nobel Laureate preferred among friends and colleagues. "Chandra" also means "Moon" or "luminous" in Sanskrit. The observatory is scheduled to be launched aboard Columbia on Space Shuttle mission STS-93

Experimental Study of Turbulent Mixing and Selectivity of Competing Reactions

DTIC Science & Technology

1988-07-01

polymerization reactors ( Van der Molen et al., 1982). MIixing is also recognized as a key factor affecting overall performance of a combustor--both in terms...Eng. Sci., 28, 413 (1973). Van der Molen , T. J., A. Koenen, H. H. J. Oosterwijk, and H. Th. Van der Bend. "Effect of Process Conditions on Light-Off

Integrated Bow Waterjet for Amphibious Vehicles.

DTIC Science & Technology

1983-01-01

8217 Davidson Laboratory Report 2276, October 1982. 3. J. D. van Manen , "Open-Water Test Series with Propellers in Nozzles," International Shipbuilding Progress...Volume 1, No. 2, 1954, pg. 99. 4. W.P.A. van Lammeren, J. D. van Manen and M.W.C. Oosterveld, "The Wageningen B-Screw Series," Trans. SNAME 1969, pg

The Soviet Academy of Sciences and Technological Development

DTIC Science & Technology

1980-12-01

Mikulinskiy, Director of the Institute of the History of Science and Technology, 1VAN SSSR, No. 7, 1977, p. 89. 2The Russian word vnedreniye means...of the History of Science and Technology, Moscow, 1970. 2VAN SSSR, No. 9, 1976, p. 20. 3vAN SSSR, No. 2, 1977, p. 8. 19 found it necessary to

Multiple Voices in Charles Van Riper's Desensitization Therapy

ERIC Educational Resources Information Center

Leahy, Margaret M.

2008-01-01

Background: Charles Van Riper (1905-94) author, researcher and practitioner, was one of the major contributors to the field of stuttering in the 20th century. His series of Action Therapy videotapes provide a useful model of how therapy was implemented by a master clinician. Aims: Van Riper's session with a client is analysed to reveal how voices…

An Empirical Introduction to the Concept of Chemical Element Based on Van Hiele's Theory of Level Transitions

ERIC Educational Resources Information Center

Vogelezang, Michiel; Van Berkel, Berry; Verdonk, Adri

2015-01-01

Between 1970 and 1990, the Dutch working group "Empirical Introduction to Chemistry" developed a secondary school chemistry education curriculum based on the educational vision of the mathematicians van Hiele and van Hiele-Geldof. This approach viewed learning as a process in which students must go through discontinuous level transitions…

Cylinders and Seances: Elise van Calcar and the Spirit of Froebel

ERIC Educational Resources Information Center

Bakker, Nelleke

2013-01-01

This essay discusses the life and work of Elise van Calcar (1822-1904), a writer and maternal feminist who introduced Froebel's kindergarten in the Netherlands. Van Calcar also was the leader of a Christian branch of spiritualism. The focus is pointed at parallels between her reading of Froebel and of "messages" from spirits in the…

Bernard van Leer Foundation Annual Review 1993 = Fundacion Bernard van Leer Revista Anual 1993.

ERIC Educational Resources Information Center

Bernard Van Leer Foundation, The Hague (Netherlands).

This report, in both English and Spanish versions, aims to highlight the Bernard van Leer Foundation's identity, objectives, and major activities, as well as the work undertaken by the projects the foundation supports. The review features articles on the Foundation's work on advocacy, supporting families living in disadvantaged circumstances,…

49 CFR 393.128 - What are the rules for securing automobiles, light trucks and vans?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 5 2013-10-01 2013-10-01 false What are the rules for securing automobiles, light... automobiles, light trucks and vans? (a) Applicability. The rules in this section apply to the transportation of automobiles, light trucks, and vans which individually weigh 4,536 kg. (10,000 lb) or less...

49 CFR 393.128 - What are the rules for securing automobiles, light trucks and vans?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false What are the rules for securing automobiles, light... automobiles, light trucks and vans? (a) Applicability. The rules in this section apply to the transportation of automobiles, light trucks, and vans which individually weigh 4,536 kg. (10,000 lb) or less...

49 CFR 393.128 - What are the rules for securing automobiles, light trucks and vans?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 5 2012-10-01 2012-10-01 false What are the rules for securing automobiles, light... automobiles, light trucks and vans? (a) Applicability. The rules in this section apply to the transportation of automobiles, light trucks, and vans which individually weigh 4,536 kg. (10,000 lb) or less...

49 CFR 393.128 - What are the rules for securing automobiles, light trucks and vans?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 5 2014-10-01 2014-10-01 false What are the rules for securing automobiles, light... automobiles, light trucks and vans? (a) Applicability. The rules in this section apply to the transportation of automobiles, light trucks, and vans which individually weigh 4,536 kg. (10,000 lb) or less...

49 CFR 393.128 - What are the rules for securing automobiles, light trucks and vans?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 5 2011-10-01 2011-10-01 false What are the rules for securing automobiles, light... automobiles, light trucks and vans? (a) Applicability. The rules in this section apply to the transportation of automobiles, light trucks, and vans which individually weigh 4,536 kg. (10,000 lb) or less...

77 FR 56701 - Morgan Olson, LLC, Denial of Petition for Decision of Inconsequential Noncompliance

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-13

... Olson walk-in van-type trucks having a gross vehicle weight rating (GVWR) over 4,536 kg and manufactured... model year 2009, 2010, and 2011 walk-in van-type trucks. Noncompliance: Morgan Olson states that the... walk-in van manufactured by Morgan Olson, would immediately notice this gap and realize that the door...

Van Go: A Labor of Love

ERIC Educational Resources Information Center

Williams, Jennifer

2012-01-01

Like a tapestry woven with one outstanding thread from beginning to end, the author's forty-year tenure as an art educator has its golden thread in her Van Go art outreach project. Quite literally, she takes students in a "van" and they "go," mostly on dirt roads, taking art to rural schools in Idaho, some of which have no more…

Willem van de Wall: Organizer and Innovator in Music Education and Music Therapy.

ERIC Educational Resources Information Center

Clair, Alicia Ann; Heller, George N.

1989-01-01

Examines Willem van de Wall's historically significant contributions to seminal literature on music therapy and the influence of music on behavior. Reviews van de Wall's early writings, at his work on music for children, and on music in institutions. Cites his "Music in Hospitals" as the culmination of his work in music therapy, music…

Measured and Modelled Tidal Circulation Under Ice Covered Van Mijenforden

NASA Astrophysics Data System (ADS)

Nilsen, F.

The observation and model area Van Mijenfjorden is situated at the west coast of Spits- bergen. An area of 533 km2 makes it the second largest fjord on Spitsbergen and the distance from the head to the mouth of the fjord is approximately 70 km. An 8.5km long and 1km wide island, Akseløya, is lying across the fjord mouth and blocking exchanges between the fjord and the coastal water masses outside. The sound Aksel- sundet on the northern side of the island is 1km wide and has a sill at 34m depth. On the southern side an islet, Mariaholmen, is between two sounds that are 200m wide and 2m deep, and 500m wide and 12m deep. Strong tidal currents exist in these sounds. Van Mijenfjorden has special ice conditions in that Akseløya almost closes the fjord, and comparatively little ice comes in from west. On the other hand, there are periods with fast ice in the fjord inside Akseløya longer than in other places, as the sea waves have little chance to break up fast ice here, or delay ice formation in autumn/winter. Van Mijenfjorden is often separated into two basins by a sill at 30m depth. The inner basin is typical 5km wide and has a maximum depth of 80m, while the outer basin is on average 10 km wide and has a maximum depth of 115m. Hydrographic measurements have been conducted since 1958 and up to the present. Through the last decade, The University Courses on Svalbard (UNIS) has used this fjord as a laboratory for their student excursions, in connection to courses in air-ice- ocean interaction and master programs, and build up an oceanographic data base. In this work, focus is put on the wintertime situation and the circulation under an ice covered fjord. Measurements show a mean cyclonic circulation pattern in the outer basin with tidal oscillation (mainly M2) superposed on this mean vector. A three- dimensional sigma layered numerical model called Bergen Ocean Model (BOM) was used to simulate the circulation in Van Mijenfjorden with only tidal forcing. The four most pronounced tidal components were used to force the model area outside Ak- seløya. The calculated cyclonic circulation pattern fits the measurements, proving that the fjord circulation is controlled by tides in periods when the ice cover shade the fjord water masses from direct wind forcing.

Validation of VITEK 2 Version 4.01 Software for Detection, Identification, and Classification of Glycopeptide-Resistant Enterococci

PubMed Central

Abele-Horn, Marianne; Hommers, Leif; Trabold, René; Frosch, Matthias

2006-01-01

We evaluated the ability of the new VITEK 2 version 4.01 software to identify and detect glycopeptide-resistant enterococci compared to that of the reference broth microdilution method and to classify them into the vanA, vanB, vanC1, and vanC2 genotypes. Moreover, the accuracy of antimicrobial susceptibility testing with agents with improved potencies against glycopeptide-resistant enterococci was determined. A total of 121 enterococci were investigated. The new VITEK 2 software was able to identify 114 (94.2%) enterococcal strains correctly to the species level and to classify 119 (98.3%) enterococci correctly to the glycopeptide resistance genotype level. One Enterococcus casseliflavus strain and six Enterococcus faecium vanA strains with low-level resistance to vancomycin were identified with low discrimination, requiring additional tests. One of the vanA strains was misclassified as the vanB type, and one glycopeptide-susceptible E. facium wild type was misclassified as the vanA type. The overall essential agreements for antimicrobial susceptibility testing results were 94.2% for vancomycin, 95.9% for teicoplanin, 100% for quinupristin-dalfopristin and moxifloxacin, and 97.5% for linezolid. The rates of minor errors were 9% for teicoplanin and 5% for the other antibiotic agents. The identification and susceptibility data were produced within 4 h to 6 h 30 min and 8 h 15 min to 12 h 15 min. In conclusion, use of VITEK 2 version 4.01 software appears to be a reliable method for the identification and detection of glycopeptide-resistant enterococci as well as an improvement over the use of the former VITEK 2 database. However, a significant reduction in the detection time would be desirable. PMID:16390951

Faster and economical screening for vancomycin-resistant enterococci by sequential use of chromogenic agar and real-time polymerase chain reaction.

PubMed

Tan, Thean Yen; Jiang, Boran; Ng, Lily Siew Yong

2017-08-01

Screening for vancomycin-resistant enterococci (VRE) by culture takes days to generate results, while polymerase chain reaction (PCR) testing directly from clinical specimens lacks specificity. The aims of this study were to develop a real-time PCR to detect and identify Enterococcus faecium, Enterococcus faecalis, and vanA and vanB genes, and to evaluate the impact of this PCR on test-reporting times when performing it directly from suspect VRE isolates present on screening chromogenic media. The tetraplex PCR primers were designed to amplify E. faecium, E. faecalis, and vanA and vanB genes, with melt-curve analysis of PCR products. Following analytical and clinical validation of the molecular assay, PCR testing was performed for target colonies present on VRE chromogenic media. PCR results were evaluated against conventional phenotypic identification and susceptibility testing, with the time to result being monitored for both modalities. A total of 519 colonies from clinical specimens were tested concurrently by real-time PCR and phenotypic methods. In all, 223 isolates were identified with phenotypic vancomycin resistance (vanA, n = 108; vanB, n = 105; non-vanA/vanB = 10), with complete agreement between PCR and phenotypic testing for vancomycin-resistant E. faecium and E. faecalis. The majority (88.6%) of PCR results were reported, on average, 24.8 hours earlier than those of phenotypic testing, with 68% reduction in total costs. The use of culture on selective media, followed by direct colony PCR confirmation allows faster and economical VRE screening. Copyright © 2015. Published by Elsevier B.V.

Clinical Characteristics and Outcomes of Late-Onset BK Virus Nephropathy in Kidney and Kidney-Pancreas Transplant Recipients.

PubMed

Imlay, Hannah; Whitaker, Kathryn; Fisher, Cynthia E; Limaye, Ajit P

2018-05-29

BK virus nephropathy (BKPyVAN) is a major complication in kidney transplant recipients (KTR) and typically occurs within 1 year of transplant. Guidelines vary in recommendations for BKPyV screening beyond 1 year. A systematic characterization of risk factors and outcomes of late-onset (>1 year) BKPyVAN has not previously been reported. We retrospectively compared characteristics and outcomes of early- (<1 year) and late-onset BKPyVAN (definitive [biopsy-confirmed] or presumptive [plasma BKPyV >10,000 copies/mL]) in a cohort of 671 KTR and simultaneous kidney-pancreas transplant (SPK) recipients between 2008 and 2013 at a single US transplant center. Proportions were compared using Chi square or Fisher's exact test with p < 0.05 considered significant. BKPyVAN was diagnosed in 96 (14.3%) patients (proven 16.7%, presumptive 83.3%): 79 (82.3%) early- and 17 (17.7%) late-onset. The proportion with late-onset BKPyVAN was significantly higher among SPK than KTR (4 of 7 [57.1%] vs 13 of 89 [14.6%], p=0.017). Late-onset represented "de novo" infection (no BKPyV detection within the first year) in 14 (82.4%) and progression of earlier lower-grade BKPyV reactivation in 3 (17.6%). Clinical outcomes were similar for early- and late-onset BKPyVAN (p>0.05 all comparisons). In a pooled analysis of prior studies of BKPyVAN in SPK recipients, 62.9% (17 of 27) were late-onset. A significant proportion of BKPyVAN is late-onset, especially among SPK recipients, and supports a longer duration of BKPyV monitoring for SPK recipients than recommended in some guidelines. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

VanT, a Homologue of Vibrio harveyi LuxR, Regulates Serine, Metalloprotease, Pigment, and Biofilm Production in Vibrio anguillarum

PubMed Central

Croxatto, Antony; Chalker, Victoria J.; Lauritz, Johan; Jass, Jana; Hardman, Andrea; Williams, Paul; Cámara, Miguel; Milton, Debra L.

2002-01-01

Vibrio anguillarum possesses at least two N-acylhomoserine lactone (AHL) quorum-sensing circuits, one of which is related to the luxMN system of Vibrio harveyi. In this study, we have cloned an additional gene of this circuit, vanT, encoding a V. harveyi LuxR-like transcriptional regulator. A V. anguillarum ΔvanT null mutation resulted in a significant decrease in total protease activity due to loss of expression of the metalloprotease EmpA, but no changes in either AHL production or virulence. Additional genes positively regulated by VanT were identified from a plasmid-based gene library fused to a promoterless lacZ. Three lacZ fusions (serA::lacZ, hpdA-hgdA::lacZ, and sat-vps73::lacZ) were identified which exhibited decreased expression in the ΔvanT strain. SerA is similar to 3-phosphoglycerate dehydrogenases and catalyzes the first step in the serine-glycine biosynthesis pathway. HgdA has identity with homogentisate dioxygenases, and HpdA is homologous to 4-hydroxyphenylpyruvate dioxygenases (HPPDs) involved in pigment production. V. anguillarum strains require an active VanT to produce high levels of an l-tyrosine-induced brown color via HPPD, suggesting that VanT controls pigment production. Vps73 and Sat are related to Vibrio cholerae proteins encoded within a DNA locus required for biofilm formation. A V. anguillarum ΔvanT mutant and a mutant carrying a polar mutation in the sat-vps73 DNA locus were shown to produce defective biofilms. Hence, a new member of the V. harveyi LuxR transcriptional activator family has been characterized in V. anguillarum that positively regulates serine, metalloprotease, pigment, and biofilm production. PMID:11872713

VanT, a homologue of Vibrio harveyi LuxR, regulates serine, metalloprotease, pigment, and biofilm production in Vibrio anguillarum.

PubMed

Croxatto, Antony; Chalker, Victoria J; Lauritz, Johan; Jass, Jana; Hardman, Andrea; Williams, Paul; Cámara, Miguel; Milton, Debra L

2002-03-01

Vibrio anguillarum possesses at least two N-acylhomoserine lactone (AHL) quorum-sensing circuits, one of which is related to the luxMN system of Vibrio harveyi. In this study, we have cloned an additional gene of this circuit, vanT, encoding a V. harveyi LuxR-like transcriptional regulator. A V. anguillarum Delta vanT null mutation resulted in a significant decrease in total protease activity due to loss of expression of the metalloprotease EmpA, but no changes in either AHL production or virulence. Additional genes positively regulated by VanT were identified from a plasmid-based gene library fused to a promoterless lacZ. Three lacZ fusions (serA::lacZ, hpdA-hgdA::lacZ, and sat-vps73::lacZ) were identified which exhibited decreased expression in the Delta vanT strain. SerA is similar to 3-phosphoglycerate dehydrogenases and catalyzes the first step in the serine-glycine biosynthesis pathway. HgdA has identity with homogentisate dioxygenases, and HpdA is homologous to 4-hydroxyphenylpyruvate dioxygenases (HPPDs) involved in pigment production. V. anguillarum strains require an active VanT to produce high levels of an L-tyrosine-induced brown color via HPPD, suggesting that VanT controls pigment production. Vps73 and Sat are related to Vibrio cholerae proteins encoded within a DNA locus required for biofilm formation. A V. anguillarum Delta vanT mutant and a mutant carrying a polar mutation in the sat-vps73 DNA locus were shown to produce defective biofilms. Hence, a new member of the V. harveyi LuxR transcriptional activator family has been characterized in V. anguillarum that positively regulates serine, metalloprotease, pigment, and biofilm production.

Emergence of vancomycin resistance in the genus Streptococcus: characterization of a vanB transferable determinant in Streptococcus bovis.

PubMed Central

Poyart, C; Pierre, C; Quesne, G; Pron, B; Berche, P; Trieu-Cuot, P

1997-01-01

Streptococcus bovis NEM760 was isolated from a stool swab collected on admission from a patient as surveillance for vancomycin-resistant enterococci. Strain NEM760 was identified as S. bovis by conventional biochemical methods and partial sequence analysis of its 16S rRNA. This strain was resistant to a low level of vancomycin (MIC, 64 micrograms/ml) but was susceptible to teicoplanin (MIC, 1 micrograms/ml), and vancomycin induced resistance to both glycopeptides. The presence of a vanB-related gene in NEM760 was demonstrated in a PCR assay which enabled specific amplification of a 635-hp internal segment of vanB. Sequence analysis of the corresponding PCR product revealed that it was highly homologous (96% identity) to the prototype vanB sequence of Enterococcus faecalis V583. The VanB resistance of determinant of S. bovis NEM760 was transferred by conjugation to E. faecalis and Enterococcus faecium at a similar frequency of 2 x 10(-5) per donor. SmaI-digested genomic DNAs of independently obtained transconjugants of E. faecalis and E. faecium were analyzed by pulsed-field gel electrophoresis and Southern hybridization with a vanB DNA probe. The electrophoretic and hybridization patterns obtained with all transconjugants of the same species were indistinguishable and revealed vanB-containing chromosomal insertions of approximately 100 kb. These results suggest that the genes mediating VanB-type resistance in S. bovis NEM760 are part of large transferable genetic elements. The results presented in the report demonstrate for the first time the role of streptococci in the dissemination of vancomycin resistance among gram-positive bacteria. PMID:8980749

Paint it Black: Using Change-Point Analysis to Investigate Increasing Vulnerability to Depression towards the End of Vincent van Gogh's Life.

PubMed

van Emmerik, Arnold A P; Hamaker, Ellen L

2017-09-04

This study investigated whether Vincent van Gogh became increasingly self-focused-and thus vulnerable to depression-towards the end of his life, through a quantitative analysis of his written pronoun use over time. A change-point analysis was conducted on the time series formed by the pronoun use in Van Gogh's letters. We used time as a predictor to see whether there was evidence for increased self-focus towards the end of Van Gogh's life, and we compared this to the pattern in the letters written before his move to Arles. Specifically, we examined Van Gogh's use of first person singular pronouns (FPSP) and first person plural pronouns (FPPP) in the 415 letters he wrote while working as an artist before his move to Arles, and in the next 248 letters he wrote after his move to Arles until his death in Auvers-sur-Oise. During the latter period, Van Gogh's use of FPSP showed an annual increase of 0.68% ( SE = 0.15, p < 0.001) and his use of FPPP showed an annual decrease of 0.23% ( SE = 0.04, p < 0.001), indicating increasing self-focus and vulnerability to depression. This trend differed from Van Gogh's pronoun use in the former period (which showed no significant trend in FPSP, and an annual increase of FPPP of 0.03%, SE = 0.02, p = 0.04). This study suggests that Van Gogh's death was preceded by a gradually increasing self-focus and vulnerability to depression. It also illustrates how existing methods (i.e., quantitative linguistic analysis and change-point analysis) can be combined to study specific research questions in innovative ways.

Paint it Black: Using Change-Point Analysis to Investigate Increasing Vulnerability to Depression towards the End of Vincent van Gogh’s Life

PubMed Central

van Emmerik, Arnold A. P.; Hamaker, Ellen L.

2017-01-01

This study investigated whether Vincent van Gogh became increasingly self-focused—and thus vulnerable to depression—towards the end of his life, through a quantitative analysis of his written pronoun use over time. A change-point analysis was conducted on the time series formed by the pronoun use in Van Gogh’s letters. We used time as a predictor to see whether there was evidence for increased self-focus towards the end of Van Gogh’s life, and we compared this to the pattern in the letters written before his move to Arles. Specifically, we examined Van Gogh’s use of first person singular pronouns (FPSP) and first person plural pronouns (FPPP) in the 415 letters he wrote while working as an artist before his move to Arles, and in the next 248 letters he wrote after his move to Arles until his death in Auvers-sur-Oise. During the latter period, Van Gogh’s use of FPSP showed an annual increase of 0.68% (SE = 0.15, p < 0.001) and his use of FPPP showed an annual decrease of 0.23% (SE = 0.04, p < 0.001), indicating increasing self-focus and vulnerability to depression. This trend differed from Van Gogh’s pronoun use in the former period (which showed no significant trend in FPSP, and an annual increase of FPPP of 0.03%, SE = 0.02, p = 0.04). This study suggests that Van Gogh’s death was preceded by a gradually increasing self-focus and vulnerability to depression. It also illustrates how existing methods (i.e., quantitative linguistic analysis and change-point analysis) can be combined to study specific research questions in innovative ways. PMID:28869542

Isotope separation by photodissociation of Van der Waal's molecules

DOEpatents

Lee, Yuan T.

1977-01-01

A method of separating isotopes based on the dissociation of a Van der Waal's complex. A beam of molecules of a Van der Waal's complex containing, as one partner of the complex, a molecular species in which an element is present in a plurality of isotopes is subjected to radiation from a source tuned to a frequency which will selectively excite vibrational motion by a vibrational transition or through electronic transition of those complexed molecules of the molecular species which contain a desired isotope. Since the Van der Waal's binding energy is much smaller than the excitational energy of vibrational motion, the thus excited Van der Waal's complex dissociate into molecular components enriched in the desired isotope. The recoil velocity associated with vibrational to translational and rotational relaxation will send the separated molecules away from the beam whereupon the product enriched in the desired isotope can be separated from the constituents of the beam.

Communication: Determining the structure of the N{sub 2}Ar van der Waals complex with laser-based channel-selected Coulomb explosion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, Chengyin, E-mail: cywu@pku.edu.cn; Liu, Yunquan; Gong, Qihuang

2014-04-14

We experimentally reconstructed the structure of the N{sub 2}Ar van der Waals complex with the technique of laser-based channel-selected Coulomb explosion imaging. The internuclear distance between the N{sub 2} center of mass and the Ar atom, i.e., the length of the van der Waals bond, was determined to be 3.88 Å from the two-body explosion channels. The angle between the van der Waals bond and the N{sub 2} principal axis was determined to be 90° from the three-body explosion channels. The reconstructed structure was contrasted with our high level ab initio calculations. The agreement demonstrated the potential application of laser-basedmore » Coulomb explosion in imaging transient molecular structure, particularly for floppy van der Waals complexes, whose structures remain difficult to be determined by conventional spectroscopic methods.« less

Analysis of the world epidemiological situation among vancomycin-resistant Enterococcus faecium infections and the current situation in Poland

PubMed

Talaga-Ćwiertnia, Katarzyna; Bulanda, Małgorzata

2018-01-01

Vancomycin-resistant Enterococcus faecium (VREfm) strains have become an important hospital pathogen due to their rapid spread, high mortality rate associated with infections and limited therapeutic options. Vancomycin resistance is predominantly mediated by VanA or VanB phenotypes, which differ as regards maintaining sensitivity to teicoplanin in the VanB phenotype. The majority of VREfm cases in the United States, Europe, Korea, South America and Africa are currently caused by the VanA phenotype. However, the epidemics in Australia and Singapore are chiefly brought about by the VanB phenotype. The rate of VREfm isolate spread varies greatly. The greatest percentage of VREfm is now recorded in the USA, Ireland and Australia. Supervision of VRE is implemented to varying degrees. Therefore, the epidemiological situation in some countries is difficult to assess due to limited data or lack thereof.

Vibration-rotation-tunneling spectroscopy of the van der Waals Bond: A new look at intermolecular forces

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cohen, R.C.; Saykally, R.J.

Measurements of the low-frequency van der Waals vibrations in weakly bound complexes by high-resolution laser spectroscopy provide a means to probe intermolecular forces at unprecedented levels of detail and precision. Several new methods are presently being used to record vibration/rotation-tunneling (VRT) transitions associated with the motions of the weak bonds in van der Waals clusters. The most direct measurements are those probing only the van der Waals modes themselves, which occur at far-infrared wavelengths. This article presents a review of the information on both intramolecular forces and intramolecular dynamics that has been obtained from far-infrared VRT spectra of 18 complexesmore » during the past several years. Some rotationally resolved measurements of van der Waals modes observed in combination with electronic or vibrational excitation are also discussed. 185 refs., 15 figs., 1 tab.« less

Histopathological grading of breast ductal carcinoma in situ: validation of a web-based survey through intra-observer reproducibility analysis.

PubMed

Schuh, Fernando; Biazús, Jorge Villanova; Resetkova, Erika; Benfica, Camila Zanella; Ventura, Alessandra de Freitas; Uchoa, Diego; Graudenz, Márcia; Edelweiss, Maria Isabel Albano

2015-07-10

Histopathological grading diagnosis of ductal carcinoma in situ (DCIS) of the breast may be very difficult even for experts, and it is important for therapeutic decisions. The challenge may be due to the inaccurate and/or subjective application of the diagnosis criteria. The aim of this study was to investigate the intra-observer agreement between a traditional method and a developed web-based questionnaire for scoring breast DCIS. A cross-sectional study was carried out to evaluate the diagnostic agreement of an electronic questionnaire and its point scoring system with the subjective reading of digital images for 3 different DCIS grading systems: Holland, Van Nuys and modified Black nuclear grade system. Three pathologists analyzed the same set of digitized images from 43 DCIS cases using two different web-based programs. In the first phase, they accessed a website with a newly created questionnaire and scoring system developed to allow the determination of the histological grade of the cases. After at least 6 months, the pathologists read again the same images, but without the help of the questionnaire, indicating subjectively the diagnoses. The intra-observer agreement analysis was employed to validate this innovative web-based survey. Overall, diagnostic reproducibility was similar for all histologic grading classification systems, with kappa values of 0.57 ± 0.10, 0.67 ± 0.09 and 0.67 ± 0.09 for Holland, Van Nuys classification and modified Black nuclear grade system respectively. Only two 2-step diagnostic disagreements were found, one for Holland and another for Van Nuys. Both cases were superestimated by the web-based survey. The diagnostic agreement between the web-based questionnaire and a traditional method, both using digital images, is moderate to good for Holland, Van Nuys and modified Black nuclear grade system. The use of a scoring point system does not appear to pose a major risk of presenting large (2-step) diagnostic disagreements. These findings indicate that the use of this point scoring system in this web-based survey to grade objectively DCIS lesions is a useful diagnostic tool.

Nodal Statistics for the Van Vleck Polynomials

NASA Astrophysics Data System (ADS)

Bourget, Alain

The Van Vleck polynomials naturally arise from the generalized Lamé equation as the polynomials of degree for which Eq. (1) has a polynomial solution of some degree k. In this paper, we compute the limiting distribution, as well as the limiting mean level spacings distribution of the zeros of any Van Vleck polynomial as N --> ∞.

A Practical Terrestrial Packet Radio Network.

DTIC Science & Technology

1983-11-01

12 Howard Frank, Israel Gitman and Richard Van Slyke , "Packet Radio System--Network Considerations," AFIPS Conference Proceedings, Anaheim, 1975...p, 1396. 33 Howard Frank, Israel Gitman and Richard Van Slyke, "Packet Radio System--Network Considerations," AFIPS...44, 1975 NCC, Anaheim, pp. 233-242. J 149 I : Frank, Howard, Israel Gitman and Richard Van Slyke, "Packet Radio System — Network

Top-Level Players' Visual Control of Interceptive Actions: Bootsma and Van Wieringen (1990) 20 Years Later

ERIC Educational Resources Information Center

Bootsma, Reinoud J.; Fernandez, Laure; Morice, Antoine H. P.; Montagne, Gilles

2010-01-01

Using a two-step approach, Van Soest et al. (2010) recently questioned the pertinence of the conclusions drawn by Bootsma and Van Wieringen (1990) with respect to the visual regulation of an exemplary rapid interceptive action: the attacking forehand drive in table tennis. In the first step, they experimentally compared the movement behaviors of…

Martin Van Buren's "Return to the Soil." Teaching with Historic Places.

ERIC Educational Resources Information Center

National Register of Historic Places, Washington, DC. Interagency Resources Div.

Using primary documents, maps, and visual data, this lesson packet focuses on Martin Van Buren and his retirement home, Lindenwald, which is on the National Register of Historic Places. The lesson materials compliment classroom study of early 19th century politics by tracing the life of Martin Van Buren and his role in the Jacksonian Era. Included…

The Effect of Designed Geometry Teaching Lesson to the Candidate Teachers' Van Hiele Geometric Thinking Level

ERIC Educational Resources Information Center

Yilmaz, Gül Kaleli; Koparan, Timur

2016-01-01

The aim of this study is to find out how designed Geometry Teaching Lesson affects candidate teachers' Van Hiele Geometric Thinking Levels. For that purpose, 14 weeks long study was performed with 44 candidate teachers who were university students in Turkey. Van Hiele Geometric Thinking Test was applied to candidate teachers before and after…

The Educational Thought of Cornelius Van Til: Philosophical Foundations of the Contemporary Christian School Movement.

ERIC Educational Resources Information Center

Maffet, Gregory J.; Dye, Charles M.

This paper gives an account of the thoughts of Cornelius Van Til on the contemporary Christian school movement. An account of the historical development of Christian compromise is given, followed by a critique of the compromise among contemporary Christian educators. Van Til claims that any educational position which falls short of being founded…

Community Music during the New Deal: The Contributions of Willem Van de Wall and Max Kaplan

ERIC Educational Resources Information Center

Krikun, Andrew

2010-01-01

Willem Van de Wall (1887-1953) and Max Kaplan (1911-98) built careers spanning music performance, music education, adult education, sociology, social work, music therapy and community music. Willem Van de Wall was a seminal influence on the development of the fields of music therapy and adult education--researching the role of music in…

Unconscious Odour Conditioning 25 Years Later: Revisiting and Extending "Kirk-Smith, Van Toller and Dodd"

ERIC Educational Resources Information Center

Zucco, Gesualdo M.; Paolini, Michela; Schaal, Benoist

2009-01-01

The pioneering work by Kirk-Smith, Van Toller, and Dodd [Kirk-Smith, M. D., Van Toller, C., & Dodd, G. H. (1983). "Unconscious odour conditioning in human subjects." "Biological Psychology," 17, 221-231], established that an unnoticed odorant paired with an emotionally meaningful task can influence mood and attitudes when the odorant alone is…

Onderzoek Naar de Bepaling van Wrijvingscoefficienten van een Voertuig uit Uitrolcurves (Research into the Determination of Friction Coefficients of a Vehicle from Deceleration Curves)

DTIC Science & Technology

1991-08-01

en Aemne Vrwaarden Wo OndOrzoeks 8 FE 1 1 opdrchl aT00’ dn wet do bereflende F B 0 1 9 terzake tussen partilon geslOlen dw:Agsu overOerikomStf...Ongemlbric~~d 9 -028 14 :259 wwWmtmd.fl 59w IEEIIIIiiiarabIg𔃽 1 c~ Vrederikkazerle, Geb. InO 03 3.. ~ van den Burchlaal 312 03 173Telefoofl 070-3166394...1ILEIDING 6 2 HET FYSISCHE MODEL 8 3 ONDERZOEK AAN DE DIFFERENTIAALVERGELIJKING 11 3.1 Existentie en uniciteit van ccii oplossing 11 3.2 Continulleit en

Time comparison via OTS-2

NASA Technical Reports Server (NTRS)

Dejong, G.; Kaarls, R.; Kirchner, D.; Ressler, H.

1982-01-01

The time comparisons carried out via OTS-2 between the Technical University Graz (Austria) and the Van Swinden Laboratory Delft (Netherlands) are discussed. The method is based on the use of the synchronization pulse in the TV-frame of the daily evening broadcasting of a French TV-program to Northern Africa. Corrections, as a consequence of changes in the position of the satellite coordinates are applied weekly after reception of satellite coordinates. A description of the method is given as well as some of the particular techniques used in both the participating laboratories. Preliminary results are presented.

Disappearance of the Supergiant Progenitor of SN 2011dh in M51

NASA Astrophysics Data System (ADS)

Van Dyk, Schuyler D.; Filippenko, Alexei V.; Fox, Ori; Kelly, Patrick; Smith, Nathan

2013-03-01

We report that in Hubble Space Telescope (HST) Wide Field Camera 3 (WFC3) observations at F555W and F814W with the UVIS channel, conducted on 2013 March 2 UT as part of our Cycle 20 Snapshot program GO-13029 (PI: A. Filippenko), we have discovered that the yellow supergiant star, identified by Van Dyk et al. (2011, ApJ, 741, L28) and Maund et al. (2011, MNRAS, 739, L37) at the position of the Type IIb SN 2011dh in M51, has vanished.

Mathematical Foundations of Programming Semantics International Conference (9th) Held in New Orleans, Louisiana, April 1993

DTIC Science & Technology

1993-04-01

Informatica 23, pp. 9 - 66 [10] Petri, C.A., Kommunikation mit Automaten, Institut fiir Instrumentelle Mathematik, Schriften des IIM, Nr. 2, Bonn 1962...Flow 122 J. W. de Bakker and Franck van Breugel An Investigation into Functions as Processes 143 Davide Sangiorgi Time Abstracted Bisimulation: Implicit...Jagadeesan: By De Morgan laws, finding a winning strategy in AOB-oA amounts to find a winning strategy in (A-oA)V’B± (where V is the dual of ®). Let A be an

Science, Sex, and Pictures: Reflections on Van Fraassen's Use of Perspectival Representations

NASA Astrophysics Data System (ADS)

Okruhlik, Kathleen

2014-03-01

Bas van Fraassen's brand of empiricism, as articulated in his well-known constructive empiricism and his more recent empiricist structuralism, has been developed using the so-called semantic approach to scientific theories. This approach has allowed van Fraassen to espouse quite a robust form of non-realism about unobservable entities while avoiding some of the problems that contributed to the demise of logical empiricism. I shall argue, however, that in other respects van Fraassen replicates many of the serious shortcomings associated with the earlier tradition -- despite the fact that his choice of language sometimes obscures those similarities. Because van Fraassen's empiricist structuralism is much less well-known than his constructive empiricism, the rather lengthy first section of this paper provides an overview and initial assessment of that position. Subsequent sections deal with the ways in which van Fraassen's very sophisticated form of empiricism not only fails to address some of the most serious shortcomings of logical empiricism but actually reinforces them. The chief focus is on the failure to address issues that arise from the historical and social contexts within which science is pursued -- this despite a vocabulary rich in references to perspectivity, pragmatics, context, use, and aims.

Effect of van der Waals forces on thermal conductance at the interface of a single-wall carbon nanotube array and silicon

NASA Astrophysics Data System (ADS)

Feng, Ya; Zhu, Jie; Tang, Dawei

2014-12-01

Molecular dynamics simulations are performed to evaluate the effect of van der Waals forces among single-wall carbon nanotubes (SWNTs) on the interfacial thermal conductance between a SWNT array and silicon substrate. First, samples of SWNTs vertically aligned on silicon substrate are simulated, where both the number and arrangement of SWNTs are varied. Results reveal that the interfacial thermal conductance of a SWNT array/Si with van der Waals forces present is higher than when they are absent. To better understand how van der Waals forces affect heat transfer through the interface between SWNTs and silicon, further constructs of one SWNT surrounded by different numbers of other ones are studied, and the results show that the interfacial thermal conductance of the central SWNT increases with increasing van der Waals forces. Through analysis of the covalent bonds and vibrational density of states at the interface, we find that heat transfer across the interface is enhanced with a greater number of chemical bonds and that improved vibrational coupling of the two sides of the interface results in higher interfacial thermal conductance. Van der Waals forces stimulate heat transfer at the interface.

Impact of Vancomycin MIC on Treatment Outcomes in Invasive Staphylococcus aureus Infections

PubMed Central

Song, Kyoung-Ho; Kim, Moonsuk; Kim, Chung Jong; Cho, Jeong Eun; Choi, Yun Jung; Park, Jeong Su; Ahn, Soyeon; Jang, Hee-Chang; Park, Kyung-Hwa; Jung, Sook-In; Yoon, Nara; Kim, Dong-Min; Hwang, Jeong-Hwan; Lee, Chang Seop; Lee, Jae Hoon; Kwak, Yee Gyung; Kim, Eu Suk; Park, Seong Yeon; Park, Yoonseon; Lee, Kkot Sil; Lee, Yeong-Seon

2016-01-01

ABSTRACT There are conflicting data on the association of vancomycin MIC (VAN-MIC) with treatment outcomes in Staphylococcus aureus infections. We investigated the relationship between high VAN-MIC and 30-day mortality and identified the risk factors for mortality in a large cohort of patients with invasive S. aureus (ISA) infections, defined as the isolation of S. aureus from a normally sterile site. Over a 2-year period, 1,027 adult patients with ISA infections were enrolled in 10 hospitals, including 673 (66%) patients with methicillin-resistant S. aureus (MRSA) infections. There were 200 (19.5%) isolates with high VAN-MIC (≥1.5 mg/liter) by Etest and 87 (8.5%) by broth microdilution (BMD). The all-cause 30-day mortality rate was 27.4%. High VAN-MIC by either method was not associated with all-cause 30-day mortality, and this finding was consistent across MIC methodologies and methicillin susceptibilities. We conclude that high VAN-MIC is not associated with increased risk of all-cause 30-day mortality in ISA infections. Our data support the view that VAN-MIC alone is not sufficient evidence to change current clinical practice. PMID:27956430

A novel method for simultaneous Enterococcus species identification/typing and van genotyping by high resolution melt analysis.

PubMed

Gurtler, Volker; Grando, Danilla; Mayall, Barrie C; Wang, Jenny; Ghaly-Derias, Shahbano

2012-09-01

In order to develop a typing and identification method for van gene containing Enterococcus faecium, two multiplex PCR reactions were developed for use in HRM-PCR (High Resolution Melt-PCR): (i) vanA, vanB, vanC, vanC23 to detect van genes from different Enterococcus species; (ii) ISR (intergenic spacer region between the 16S and 23S rRNA genes) to detect all Enterococcus species and obtain species and isolate specific HRM curves. To test and validate the method three groups of isolates were tested: (i) 1672 Enterococcus species isolates from January 2009 to December 2009; (ii) 71 isolates previously identified and typed by PFGE (pulsed-field gel electrophoresis) and MLST (multi-locus sequence typing); and (iii) 18 of the isolates from (i) for which ISR sequencing was done. As well as successfully identifying 2 common genotypes by HRM from the Austin Hospital clinical isolates, this study analysed the sequences of all the vanB genes deposited in GenBank and developed a numerical classification scheme for the standardised naming of these vanB genotypes. The identification of Enterococcus faecalis from E. faecium was reliable and stable using ISR PCR. The typing of E. faecium by ISR PCR: (i) detected two variable peaks corresponding to different copy numbers of insertion sequences I and II corresponding to peak I and II respectively; (ii) produced 7 melt profiles for E. faecium with variable copy numbers of sequences I and II; (iii) demonstrated stability and instability of peak heights with equal frequency within the patient sample (36.4±4.5 days and 38.6±5.8 days respectively for 192 patients); (iv) detected ISR-HRM types with as much discrimination as PFGE and more than MLST; and (v) detected ISR-HRM types that differentiated some isolates that were identical by PFGE and MLST. In conjunction with the rapid and accurate van genotyping method described here, this ISR-HRM typing and identification method can be used as a stable identification and typing method with predictable instability based on recombination and concerted evolution of the rrn operon that will complement existing typing methods. Crown Copyright © 2012. Published by Elsevier B.V. All rights reserved.

Chesapeake Bay Sediment Flux Model

DTIC Science & Technology

1993-06-01

1988; Van der Molen , -88- 1991; Yoshida, 1981.) The model developed below is based on both of these approaches. It incorporates the diagenetic...288: pp. 289-333. Van der Molen , D.T. (1991): A simple, dynamic model for the simulation of the release of phosphorus from sediments in shallow...1974; Berner, 1980; van Cappellen and Berner, 1988). These relate the diagenetic production of phosphate to the resulting pore water concentration

Perception for Outdoor Navigation

DTIC Science & Technology

1991-12-01

are theories of human cognitive activity during driving. Van der Molen and Botticher recently reviewed several of these models [40]. The models...represent driving knowledge, how to perceive traffic situations, or how to process information to obtain actions. Van der Molen and Botticher attempted to...Conference on Robotics and Automation. IEEE, 1987. [40] van der Molen , H.H., and Botticher, A.M.T. Risk Models for Traffic Participants: A Concerted

The Role of Rad17 in DNA Damage Checkpoint Signaling and Initiation of Apoptosis in Mammary Cells

DTIC Science & Technology

2005-07-01

Shen et al. 1998). Antibodies to β-catenin (Transduction lab ), GSK-3β (Santa Cruz), Smad3 I-20 (Santa Cruz), Smad3 (Zymed), phspho-Smad2 (Cell...van de Wetering, M., R. Cavallo, D. Dooijes, M. van Beest , J. van Es, J. Loureiro, A. Ypma, D. Hursh, T. Jones, A. Bejsovec, M. Peifer, M. Mortin

Optimizing of In Situ Bioremediation Technology to Manage Perchlorate-Contaminated Groundwater

DTIC Science & Technology

2003-03-01

template using the best fitness values. MOMGA then executes another cycle of initialization, primordial, and juxtapositional phases ( Van Veldhuizen ...Implementation of In Situ Remediation Technologies,” Journal of Contaminant Hydrology, 37(3): 295-317, 1999. Coello Coello, A. C., D.A. Van Veldhuizen , and G.B...Environmental Management. 56: 79-95, 1999. Van Veldhuizen , David A. Multiobjective Evolutionary Algorithms: Classifications, Analyses, and New

The research contributions of Dr. Paul Van Deusen

Treesearch

Thomas B. Lynch; Francis A. Roesch; John Paul McTague; Jeffrey H. Gove; Gregory A. Reams; Aaron R. Weiskittel

2015-01-01

Dr. Paul Van Deusen’s recent passing concluded a rich 30+-year research career dedicated to development and implementation of quantitative methods for forestry and natural resources. Since the early part of his career as a biometrician with the USDA Forest Service Southern Research Station in the 1980s-1990s and continuing with his later employment at NCASI, Dr. Van...

Effective field theories for van der Waals interactions

NASA Astrophysics Data System (ADS)

Brambilla, Nora; Shtabovenko, Vladyslav; Tarrús Castellà, Jaume; Vairo, Antonio

2017-06-01

Van der Waals interactions between two neutral but polarizable systems at a separation R much larger than the typical size of the systems are at the core of a broad sweep of contemporary problems in settings ranging from atomic, molecular and condensed matter physics to strong interactions and gravity. In this paper, we reexamine the dispersive van der Waals interactions between two hydrogen atoms. The novelty of the analysis resides in the usage of nonrelativistic effective field theories of quantum electrodynamics. In this framework, the van der Waals potential acquires the meaning of a matching coefficient in an effective field theory, dubbed van der Waals effective field theory, suited to describe the low-energy dynamics of an atom pair. It may be computed systematically as a series in R times some typical atomic scale and in the fine-structure constant α . The van der Waals potential gets short-range contributions and radiative corrections, which we compute in dimensional regularization and renormalize here for the first time. Results are given in d space-time dimensions. One can distinguish among different regimes depending on the relative size between 1 /R and the typical atomic bound-state energy, which is of order m α2. Each regime is characterized by a specific hierarchy of scales and a corresponding tower of effective field theories. The short-distance regime is characterized by 1 /R ≫m α2 and the leading-order van der Waals potential is the London potential. We also compute next-to-next-to-next-to-leading-order corrections. In the long-distance regime we have 1 /R ≪m α2. In this regime, the van der Waals potential contains contact terms, which are parametrically larger than the Casimir-Polder potential that describes the potential at large distances. In the effective field theory, the Casimir-Polder potential counts as a next-to-next-to-next-to-leading-order effect. In the intermediate-distance regime, 1 /R ˜m α2, a significantly more complex potential is obtained. We compare this exact result with the two previous limiting cases. We conclude by commenting on the van der Waals interactions in the hadronic case.

Vancomycin-induced acute kidney injury in elderly Chinese patients: a single-centre cross-sectional study.

PubMed

Pan, Kun-Ming; Wu, Yi; Chen, Can; Chen, Zhang-Zhang; Xu, Jian-An; Cao, Lei; Xu, Qing; Wu, Wei; Dai, Pei-Fang; Li, Xiao-Yu; Lv, Qian-Zhou

2018-04-01

The objective of the present study was to investigate the current situation concerning, and risk factors for, vancomycin (VAN)-induced acute kidney injury (VI-AKI) in elderly Chinese patients, to assess outcomes and risk factors in patients who have developed VI-AKI, in order to provide suggestions for improving the prevention and treatment of this condition in these patients. We retrospectively identified elderly older inpatients who had received four or more doses of VAN treatment. We compared patients with VI-AKI with those who received VAN treatment and had not developed AKI (NO-AKI). We defined VI-AKI as developing AKI during VAN therapy or within 3 days after withdrawal of VAN. A total of 647 out of 862 elderly inpatients were included in the study. Among those excluded, in 89.3% of cases (192/215) this was because of lack of data on serum creatinine (SCr). Among included patients, 32.5% (210/647) of patients received therapeutic drug monitoring (TDM) during VAN therapy. In 66.9% of cases (424/634), there was insufficient TDM, and in 3.9% (25/634) this was appropriate. A total of 102 patients had confirmed VI-AKI, with an incidence of 15.8% (102/647). Multiple logistic regression analysis revealed that hyperuricaemia [odds ratio (OR) = 3.045; P = 0.000)], mechanical ventilation (OR = 1.906; P = 0.022) and concomitant vasopressor therapy (OR = 1.919; P = 0.027) were independent risk factors for VI-AKI; higher serum albumin (OR = 0.885; P = 0.000) was determined to be an independent protective factor for VI-AKI. For the elderly Chinese patients treated with VAN, there was insufficient monitoring of SCr, too little use of VAN TDM, and lower rate of patients whose VAN though serum concentrations were not obtained at the correct time. We recommend that hospital managers increase investment in clinical pharmacists, to strengthen professional management. Patients with concomitant hyperuricaemia and on mechanical ventilation and vasopressor therapy should be paid more attention, and a higher serum albumin was determined to be an independent protective factor for VI-AKI. © 2018 The British Pharmacological Society.

Moment tensor inversion of recent local moderate sized Van Earthquakes: seismicity and active tectonics of the Van region : Eastern Turkey

NASA Astrophysics Data System (ADS)

Kalafat, D.; Suvarikli, M.; Ogutcu, Z.; Kekovali, K.; Ocal, M. F.; Gunes, Y.; Pinar, A.

2013-12-01

The study area of the present research, the Van Region is located at the norththern end of the collision zone between the Anatolia and Arabian plates. Therefore, the southeast border of the Anatolian plate collides with the Arabian plate along the Bitlis Suture Zone. This zone is formed by collision of Arabian and in large scale Eurasian plates at mid-Miocen age. This type of thrust generation as a result of compressional regime extends east-west. The largest recorded earthquakes have all taken place along Southern Turkey (e.g. Lice, 1971; Varto, 1966; Caldiran, 1976). On the 23th of October 2011, an earthquake shook the Van Lake, Eastern Turkey, following a seismic sequence of more than three months in an unprecedented episode for this region characterized by null or low seismicity. The October 23, 2011 Van-Ercis Earthquake (Mw=7.1) was the most devastating resulting in loss of life and destruction. In order to study the aftershocks' activity of this main event, we installed and kept a seismic network of 10 broad-band (BB) stations in the area for an interval of nearly fifteen months. We characterized the seismogenic structure of the zone by calculating a minimum 1-D local velocity model and obtaining precise hypocentre locations. We also calculated fault plane solutions for more than 200 moderate sized earthquakes based on first motion polarities and commonly Moment Tensor Inversion Methods. The seismogenic zone would be localized at aproximately 10 km depth. Generally, the distribution of the important moderate earthquakes and the aftershock distribution shows that the E-W and NE-SW oriented fault segments cause the earthquake activities. Aftershock events are located along the eastern border of Lake Van and mainly between 5 and 10 km depth and disposed in two alignments: a ~E-W-trending alignment that matches with the trace of the Van Trust fault Zone and a NE-trending which could correspond to an structure not previously seen. Selected focal mechanisms show a strong trust faulting which coincides with the nature of the Van fault. We were currently analysing an archive of over 5000 local events recorded by the KOERI seismic network of over 20 broadband stations between 2010 and 2013 in the whole Van Region. The Van Earthquake initiated and caused an increase in seismic activity of the region. Van Earthquake and its important aftershocks fault mechanism solutions show that the region is under compression and reverse faulting is a result of this regime which is effective on the active compressional tectonics of the region. This study was supported by Bogazici University Research Projects Commission under SRP/BAP project No. 6040.

A summary of the OV1-19 satellite dose, depth dose, and linear energy transfer spectral measurements

NASA Technical Reports Server (NTRS)

Cervini, J. T.

1972-01-01

Measurements of the biophysical and physical parameters in the near earth space environment, specifically, the Inner Van Allen Belt are discussed. This region of space is of great interest to planners of the Skylab and the Space Station programs because of the high energy proton environment, especially during periods of increased solar activity. Many physical measurements of charged particle flux, spectra, and pitch angle distribution have been conducted and are programmed in the space radiation environment. Such predictions are not sufficient to accurately predict the effects of space radiations on critical biological and electronic systems operating in these environments. Some of the difficulties encountered in transferring from physical data to a prediction of the effects of space radiation on operational systems are discussed.

Fermentation, phlogiston and matter theory: chemistry and natural philosophy in Georg Ernst Stahl's Zymotechnia Fundamentalis.

PubMed

Chang, Ku-Ming Kevin

2002-01-01

This paper examines Georg Ernst Stahl's first book, the Zymotechnia Fundamentalis, in the context of contemporary natural philosophy and the author's career. I argue that the Zymotechnia was a mechanical theory of fermentation written consciously against the influential "fermentational program" of Joan Baptista van Helmont and especially Thomas Willis, Stahl's theory of fermentation introduced his first conception of phlogiston, which was in part a corpuscular transformation of the Paracelsian sulphur principle. Meanwhile some assumptions underlying this theory, such as the composition of matter, the absolute passivity of matter and the "passions" of sulphur, reveal the combined scholastic and mechanistic character of Stahl's natural philosophy. In the conclusion I show that Stahl's theory of fermentation undermined the old fermentational program and paved the way for his dualist vitalism.

Place-based education: a transformative activist stance

NASA Astrophysics Data System (ADS)

Coughlin, Christine A.; Kirch, Susan A.

2010-12-01

The ethnography presented by van Eijck and Roth focuses on the activities of people involved in a government funded internship program in conservation and restoration, which was offered by a `multidisciplinary research center' through a local First Nation adult education center. The internship was designed, in partnership with a local non-profit conservation society (OceanHealth), to appeal to First Nation men and women considering career change, returning to school, or re-entering the work place. The primary aim of the internship was to `provide authentic science for diverse student populations (and their teachers), with particular attention to the needs of students from First Nations, to become scientifically literate to the extent that it prepares them for participating in public debates, community decision-making, and personal living consistent with long-term environmentally sustainable forms of life'. The authors report that at least one of the two interns was not interested in science and a WSÁNEC elder expressed dissatisfaction with the efforts to establish the nature park and its current approved uses. Van Eijck and Roth argue that the divergence between the project aims and the goals of the participants are a result of how `place' is viewed in place-based education and that disagreements like these can be resolved if place is theorized as chronotope. There are many interesting ideas raised and directions taken in the article by van Eijck and Roth. After several discussions during the review process, we decided to focus our forum response on the meaning of `place' in place-based education, the utility of theorizing place as a chronotope, the implications for teaching-learning (`education'), and musings on what remains unclear.

Cost-effectiveness of finding new HIV diagnoses using rapid HIV testing in community-based organizations.

PubMed

Shrestha, Ram K; Clark, Hollie A; Sansom, Stephanie L; Song, Binwei; Buckendahl, Holly; Calhoun, Cindy B; Hutchinson, Angela B; Heffelfinger, James D

2008-01-01

We assessed the cost-effectiveness of determining new human immunodeficiency virus (HIV) diagnoses using rapid HIV testing performed by community-based organizations (CBOs) in Kansas City, Missouri, and Detroit, Michigan. The CBOs performed rapid HIV testing during April 2004 through March 2006. In Kansas City, testing was performed in a clinic and in outreach settings. In Detroit, testing was performed in outreach settings only. Both CBOs used mobile testing vans. Measures of effectiveness were the number of HIV tests performed and the number of people notified of new HIV diagnoses, based on rapid tests. We retrospectively collected program costs, including those for personnel, test kits, mobile vans, and facility space. The CBO in Kansas City tested a mean of 855 people a year in its clinic and 703 people a year in outreach settings. The number of people notified of new HIV diagnoses was 19 (2.2%) in the clinic and five (0.7%) in outreach settings. The CBO in Detroit tested 976 people a year in outreach settings, and the number notified of new HIV diagnoses was 15 (1.5%). In Kansas City, the cost per person notified of a new HIV diagnosis was $3,637 in the clinic and $16,985 in outreach settings. In the Detroit outreach settings, the cost per notification was $13,448. The cost of providing a new HIV diagnosis was considerably higher in the outreach settings than in the clinic. The variation can be largely explained by differences in the number of undiagnosed infections among the people tested and by the costs of purchasing and operating a mobile van.

New results from the Colorado CubeSat and comparison with Van Allen Probes data

NASA Astrophysics Data System (ADS)

Li, X.

2013-05-01

The Colorado Student Space Weather Experiment (CSSWE) is a 3-unit (10cm x 10cm x 30cm) CubeSat mission funded by the NSF, launched into a highly inclined (650) low-Earth (490km x 790km) orbit on 09/13/12 as a secondary payload under NASA's Educational Launch of Nanosatellites (ELaNa) program. CSSWE contains a single science payload, the Relativistic Electron and Proton Telescope integrated little experiment (REPTile), which is a simplified and miniaturized version of the Relativistic Electron and Proton Telescope (REPT) built at the Laboratory for Atmospheric and Space Physics (LASP) of University of Colorado for NASA/Van Allen Probes mission, which consists of two identical spacecraft, launched on 08/30/12, that traverse the heart of the radiation belts in a low inclination (100) orbit. REPTile is designed to measure the directional differential flux of protons ranging from 9 to 40 MeV and electrons from 0.5 to >3.3 MeV. Three-month science mission (full success) was completed on 1/05/13. We are now into the extended mission phase, focusing on data analysis and modeling. REPTile measures a fraction of the total population that has small enough equatorial pitch angles to reach the altitude of CSSWE, thus measuring the precipitating population as well as the trapped population. These measurements are critical for understanding the loss of outer radiation belt electrons. New results from CSSWE and comparison with Van Allen Probes data will be presented. The CSSWE is also an ideal class project, involving over 65 graduate and undergraduate students and providing training for the next generation of engineers and scientists over the full life-cycle of a satellite project.

Evaluation of BBL CHROMagar VanRE for detection of vancomycin-resistant Enterococci in rectal swab specimens.

PubMed

Stamper, Paul D; Shulder, Stephanie; Bekalo, Pearl; Manandhar, Deepika; Ross, Tracy L; Speser, Sharon; Kingery, Julie; Carroll, Karen C

2010-11-01

A study was performed on 517 surveillance rectal swabs to evaluate a selective and differential chromogenic medium, the BBL CHROMagar VanRE (CVRE), which enables recovery and identification of VanA- and VanB-containing Enterococcus faecium (ENFM) and Enterococcus faecalis (ENFS) isolates. Compared to BBL Enterococcosel agar, a bile-esculin-azide-vancomycin (BEAV) agar, the initial overall sensitivity, specificity, and positive and negative predictive values of CVRE for the detection of vancomycin-resistant ENFM and ENFS were 99.1% and 94.8% and 84.2% and 99.7%, respectively. Among our patient population, more vancomycin-resistant enterococci (VRE) were recovered with CVRE than BEAV.

Evaluation of BBL CHROMagar VanRE for Detection of Vancomycin-Resistant Enterococci in Rectal Swab Specimens▿

PubMed Central

Stamper, Paul D.; Shulder, Stephanie; Bekalo, Pearl; Manandhar, Deepika; Ross, Tracy L.; Speser, Sharon; Kingery, Julie; Carroll, Karen C.

2010-01-01

A study was performed on 517 surveillance rectal swabs to evaluate a selective and differential chromogenic medium, the BBL CHROMagar VanRE (CVRE), which enables recovery and identification of VanA- and VanB-containing Enterococcus faecium (ENFM) and Enterococcus faecalis (ENFS) isolates. Compared to BBL Enterococcosel agar, a bile-esculin-azide-vancomycin (BEAV) agar, the initial overall sensitivity, specificity, and positive and negative predictive values of CVRE for the detection of vancomycin-resistant ENFM and ENFS were 99.1% and 94.8% and 84.2% and 99.7%, respectively. Among our patient population, more vancomycin-resistant enterococci (VRE) were recovered with CVRE than BEAV. PMID:20739492

Van Driest transformation and compressible wall-bounded flows

NASA Technical Reports Server (NTRS)

Huang, P. G.; Coleman, G. N.

1994-01-01

The transformation validity question utilizing resulting data from direct numerical simulations (DNS) of supersonic, isothermal cold wall channel flow was investigated. The DNS results stood for a wide scope of parameter and were suitable for the purpose of examining the generality of Van Driest transformation. The Van Driest law of the wall can be obtained from the inner-layer similarity arguments. It was demonstrated that the Van Driest transformation cannot be incorporated to collapse the sublayer and log-layer velocity profiles simultaneously. Velocity and temperature predictions according to the preceding composite mixing-length model were presented. Despite satisfactory congruity with the DNS data, the model must be perceived as an engineering guide and not as a rigorous analysis.

Gas Testing at the NBC-Filter of the M-Frigates of the Royal Dutch Navy According to the NATO Standard (Gastesten aan het NBC-Filter voor het M-Fregat van de oninklijke Marine volgens NAVO-eisen)

DTIC Science & Technology

1992-06-01

man de eisen van bet NAVO.-document voldsan word.. Het AstroCarb-filter bleek voor alle geteste gassen gemakkelijk de vereiste doorbroaktijden te halen ...hill ?NO famwtyn J-3r d~mf tI~nq"M#-rI~ m t~w)-im TNO RCl1 U W2 AM " TNO-por PML1 32490333 Pagins 2 Samenvatting De gasbescherniende eigenschappen van ...De schoktest tastte de prestaties van bet filter niet man. Summary The gas protective properties of an AstroCarb 200 NBC filter which is usid in the

Polyclonal emergence of vanA vancomycin-resistant Enterococcus faecium in Australia.

PubMed

van Hal, Sebastiaan J; Espedido, Björn A; Coombs, Geoffrey W; Howden, Benjamin P; Korman, Tony M; Nimmo, Graeme R; Gosbell, Iain B; Jensen, Slade O

2017-04-01

To investigate the genetic context associated with the emergence of vanA VRE in Australia. The whole genomes of 18 randomly selected vanA -positive Enterococcus faecium patient isolates, collected between 2011 and 2013 from hospitals in four Australian capitals, were sequenced and analysed. In silico typing and transposon/plasmid assembly revealed that the sequenced isolates represented (in most cases) different hospital-adapted STs and were associated with a variety of different Tn 1546 variants and plasmid backbone structures. The recent emergence of vanA VRE in Australia was polyclonal and not associated with the dissemination of a single 'dominant' ST or vanA -encoding plasmid. Interestingly, the factors contributing to this epidemiological change are not known and future studies may need to consider investigation of potential community sources. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

A Reply to the Comment on "Assessing Discrepancies Between Previous Plate Kinematic Models of Mesozoic Iberia and Their Constraints" by Barnett-Moore Et Al.

NASA Astrophysics Data System (ADS)

Barnett-Moore, N.; Font, E.; Neres, M.

2017-12-01

We welcome the comments of van Hinsbergen et al. (2017) on the recent efforts of Barnett-Moore et al. (2016). Specifically, van Hinsbergen et al. (2017) raise concerns about two of the major conclusions made by Barnett-Moore et al. (2016). First, Barnett-Moore et al. (2016) choose to negate the Cretaceous Iberian paleomagnetic database as a viable plate kinematic constraint on the plate motions of Mesozoic Iberia. This conclusion, criticized by van Hinsbergen et al. (2017), was based on citing the previous efforts of Neres et al. (2012, 2013), which exposed several shortcomings, elaborated on below, within this data set. Second, van Hinsbergen et al. (2017) criticize Barnett-Moore et al. (2016) for dismissing mantle tomographic interpretations in support of a preserved Cretaceous Pyrenean "subducted slab" beneath northern Africa. Below, we have addressed each of these major criticisms from van Hinsbergen et al. (2017) in a two-section layout, similar to their comment above.

Binding and Diffusion of Lithium in Graphite: Quantum Monte Carlo Benchmarks and Validation of van der Waals Density Functional Methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ganesh, P.; Kim, Jeongnim; Park, Changwon

2014-11-03

In highly accurate diffusion quantum Monte Carlo (QMC) studies of the adsorption and diffusion of atomic lithium in AA-stacked graphite are compared with van der Waals-including density functional theory (DFT) calculations. Predicted QMC lattice constants for pure AA graphite agree with experiment. Pure AA-stacked graphite is shown to challenge many van der Waals methods even when they are accurate for conventional AB graphite. Moreover, the highest overall DFT accuracy, considering pure AA-stacked graphite as well as lithium binding and diffusion, is obtained by the self-consistent van der Waals functional vdW-DF2, although errors in binding energies remain. Empirical approaches based onmore » point charges such as DFT-D are inaccurate unless the local charge transfer is assessed. Our results demonstrate that the lithium carbon system requires a simultaneous highly accurate description of both charge transfer and van der Waals interactions, favoring self-consistent approaches.« less

Detection of Human Fatigue

DTIC Science & Technology

2005-08-05

research (Lacey, 1974; Jennings, 1992; van der Molen , 2000; Somsen, 2004) using principally fixed foreperiod reaction time tasks demonstrated that in...U.S. Department of Transportation DOT/FAA/AM-99/28. Somsen R.J., Jennings J.R., Van der Molen M.W. (Nov 2004). The cardiac cycle time effect revisited...Temporal dynamics of the central-vagal modulation of heart rate in human reaction time tasks. Psychophysiology. 41(6), pp. 941-953. Van der Molen , M

Experience of Military Nurse Practitioners During Their First Year of Practice

DTIC Science & Technology

2000-05-01

challenges, preceptor stories, patients and practice, and looking toward the future. The data was related to Van Manen s four existential themes...existential theme categories as outlined by Van Manen (1990). The theme categories, theme clusters, and metathemes were reviewed by the researcher s...themes) in terms of which of these lived experiences can be described and interpreted constitute the immense complexity of the lifeworld ( Van Manen

Cloud Cavitation and Collective Bubble Dynamics.

DTIC Science & Technology

1986-03-15

Fundamentals of Classical Thermodynamics, Second Edition, Wiley. Van Manen , J. D. (1963), "Bent Trailing Edges of Propeller Blades of High Powered...responsible since Van Manen’s (1963) work. This is supported experimentally by a very close correlation between the dynamics of these clouds and the...needed as guidance for future design and experimentation. To our knowledge, since the early work of Van Wijngaarden (1964) only a few publications by Morch

Nonequilibrium Plasma Research

DTIC Science & Technology

2010-05-01

Kulikovsky, IEEE Trans. Plasma Sci. 25, 439 (1997). 61. W. Yi and P. Williams, J. Phys. D: Appl. Phys. 35, 205 (2002). 62. E. van Veldhuizen and W...Rutgers, J. Phys. D: Appl. Phys. 35, 2169 (2002). 63. E. van Veldhuizen , A. Baede, D. Hayashi, and W. Rutgers, APP Spring Meeting (Bad Honnef...Nonequilibrium Air Plasmas at Atmosphere Pressure, (Institute of Physics, Bristol, UK 2005) Review Article: P. Bletzinger, B. N. Ganguly, D. Van Wie and

CMMI Roadmaps

DTIC Science & Technology

2008-11-01

Attendees of the SPIder Workshop D. Bierhuizen—Medis Medical Imaging Systems L. Braafhart—LogicaCMG Nederland H.J.J. Cannegieter—SYSQA W. den...Dekker—LogicaCMG Nederland L. Delmelk—LogicaCMG België A.J. Donderman—Transfer Solutions G.H.M. Friedhoff—SYSQA L.L. van der Giessen—ABN AMRO M...Mechelen—Compuware Nederland M.P.H.M. Mermans—Philips Medical Systems C. Michielsen—ITIB N. van Mourik—SYSQA E.M. Oostveen—Advanced M.H.M. van

Perception of Motion in Statistically-Defined Displays.

DTIC Science & Technology

1988-02-15

motion encoding (Reichardt, 1961; Barlow and Levick , 1963; van Doorn and Koenderink, 1982a, b ; van de Grind, Koenderink, van Doorn, 1983). A bilocal...stimelu toetini motion onet Lca perception. Psychological Review, 87, 435-469.bo. Barlow H. B . and Levick W. R. (1963) The mechanisms of directionally...REPORT NUMBER(S) 5. MONITORING ORGANIZATIOLA OAT yOSl R 6. NAME OF PERFORMING ORGANIZATION b . OFFICE SYMBOL 7@. NAME OF MONITORING ORGANIZATION (If

In Defense of Competition during Syntactic Ambiguity Resolution

ERIC Educational Resources Information Center

Vosse, Theo; Kempen, Gerard

2009-01-01

In a recent series of publications (Traxler et al. J Mem Lang 39:558-592, 1998; Van Gompel et al. J Mem Lang 52:284-307, 2005; see also Van Gompel et al. (In: Kennedy, et al.(eds) Reading as a perceptual process, Oxford, Elsevier pp 621-648, 2000); Van Gompel et al. J Mem Lang 45:225-258, 2001) eye tracking data are reported showing that globally…

First NATO/SIBCA Exercise in Sampling of Chemical Warfare Agents (Eerste NATO/SIBCA-oefening in monstername van chemische strijdmiddelen).

DTIC Science & Technology

1998-01-01

TNO-rapport PML1997-A81 Eerste NATO/SIBCA-oefening in monster- name van chemische strijdmiddelen TNO Prins Maurits Laboratorium Lange Kleiweg...27 Aantal pagina’s : 53 (incl. bijlagen, excl. RDP & distributielijst) Aantal bijlagen : 4 TNO Prins Maurits Laboratorium is onderdeel...van de hoofdgroep TNO Defensieonderzoek waartoe verder behoren: TNO Fysisch en Elektronisch Laboratorium TNO Technische Menskunde Nederlandse

Het SOWNet Experiment (The SOWNet Experiment)

DTIC Science & Technology

2008-07-01

dat bet energieverbruik van de EQS zenders naar aanleiding van een gem-iddelde voertuigpassage circa 5 keer zo hoog is dan die van de SOWNet-zenders...code (I byte). * Een Belief- parameter (1 byte). * Een geheugenindex (2 bytes). * Lijst met Destination ID-codes, aangevuld met nullen. vaste omvang 10...verwachting voldoende hoog is zal de node alarm slaan. Als een sensor een object detecteert (hetzij als een False Alarm, hetzij doordat een object

Solving Geometric Problems by Using Algebraic Representation for Junior High School Level 3 in Van Hiele at Geometric Thinking Level

ERIC Educational Resources Information Center

Suwito, Abi; Yuwono, Ipung; Parta, I. Nengah; Irawati, Santi; Oktavianingtyas, Ervin

2016-01-01

This study aims to determine the ability of algebra students who have 3 levels van Hiele levels. Follow its framework Dindyal framework (2007). Students are required to do 10 algebra shaped multiple choice, then students work 15 about the geometry of the van Hiele level in the form of multiple choice questions. The question has been tested levels…

Deterministic Combatmodels, Interim Report 1: Literature Research (Deterministische Gevechtsmodellen, Interim Rapport 1: Literatuur Onderzoek)

DTIC Science & Technology

1991-12-01

gevechtsxnodellen .. .. .. .. .. ... .. ... .. ... ... ... 9 2.3 Methodolog-Ische indeling van gevechtsmodellering. .. .. .. .. .. ... ... 10 2.4 Deterxninistische...te vinden in [2]. Er zijn verschillende methoden om. gevechtsmodellen in te delen. *op grond van doel - training en anderwijs -research 9 op grond van...duel modellen warden verwerkt. Voor deze methode wordt verwezen naax [ 11 , 12, 13]. Deze laatste twee methoden zijn nog volop in ontwikkeling en er

Colossal terahertz nonlinearity of tunneling van der Waals gap (Conference Presentation)

NASA Astrophysics Data System (ADS)

Bahk, Young-Mi; Kang, Bong Joo; Kim, Yong Seung; Kim, Joon-Yeon; Kim, Won Tae; Kim, Tae Yun; Kang, Taehee; Rhie, Ji Yeah; Han, Sanghoon; Park, Cheol-Hwan; Rotermund, Fabian; Kim, Dai-Sik

2016-09-01

We manufactured an array of three angstrom-wide, five millimeter-long van der Waals gaps of copper-graphene-copper composite, in which unprecedented nonlinearity was observed. To probe and manipulate van der Waals gaps with long wavelength electromagnetic waves such as terahertz waves, one is required to fabricate vertically oriented van der Waals gaps sandwiched between two metal planes with an infinite length in the sense of being much larger than any of the wavelengths used. By comparison with the simple vertical stacking of metal-graphene-metal structure, in our structure, background signals are completely blocked enabling all the light to squeeze through the gap without any strays. When the angstrom-sized van der Waals gaps are irradiated with intense terahertz pulses, the transient voltage across the gap reaches up to 5 V with saturation, sufficiently strong to deform the quantum barrier of angstrom gaps. The large transient potential difference across the gap facilitates electron tunneling through the quantum barrier, blocking terahertz waves completely. This negative feedback of electron tunneling leads to colossal nonlinear optical response, a 97% decrease in the normalized transmittance. Our technology for infinitely long van der Waals gaps can be utilized for other atomically thin materials than single layer graphene, enabling linear and nonlinear angstrom optics in a broad spectral range.

Materials perspective on Casimir and van der Waals interactions

NASA Astrophysics Data System (ADS)

Woods, L. M.; Dalvit, D. A. R.; Tkatchenko, A.; Rodriguez-Lopez, P.; Rodriguez, A. W.; Podgornik, R.

2016-10-01

Interactions induced by electromagnetic fluctuations, such as van der Waals and Casimir forces, are of universal nature present at any length scale between any types of systems. Such interactions are important not only for the fundamental science of materials behavior, but also for the design and improvement of micro- and nanostructured devices. In the past decade, many new materials have become available, which has stimulated the need for understanding their dispersive interactions. The field of van der Waals and Casimir forces has experienced an impetus in terms of developing novel theoretical and computational methods to provide new insights into related phenomena. The understanding of such forces has far reaching consequences as it bridges concepts in materials, atomic and molecular physics, condensed-matter physics, high-energy physics, chemistry, and biology. This review summarizes major breakthroughs and emphasizes the common origin of van der Waals and Casimir interactions. Progress related to novel ab initio modeling approaches and their application in various systems, interactions in materials with Dirac-like spectra, force manipulations through nontrivial boundary conditions, and applications of van der Waals forces in organic and biological matter are examined. The outlook of the review is to give the scientific community a materials perspective of van der Waals and Casimir phenomena and stimulate the development of experimental techniques and applications.

Recruiting Community Partners for Veggie Van: Strategies and Lessons Learned From a Mobile Market Intervention in North Carolina, 2012-2015.

PubMed

Tripicchio, Gina L; Grady Smith, Jacqueline; Armstrong-Brown, Janelle; McGuirt, Jared; Haynes-Maslow, Lindsey; Mardovich, Sarah; Ammerman, Alice S; Leone, Lucia

2017-04-27

Food access interventions are promising strategies for improving dietary intake, which is associated with better health. However, studies examining the relationship between food access and intake are limited to observational designs, indicating a need for more rigorous approaches. The Veggie Van (VV) program was a cluster-randomized intervention designed to address the gap between food access and intake. In this article, we aim to describe the approaches involved in recruiting community partners to participate in VV. The VV mobile market aimed to improve access to fresh fruits and vegetables by providing subsidized, high-quality, local produce in low-resource communities in North Carolina. This study describes the strategies and considerations involved in recruiting community partners and individual participants for participation in the VV program and evaluation. To recruit partners, we used various strategies, including a site screener to identify potential partners, interest forms to gauge future VV use and prioritize enrollment of a high-need population, marketing materials to promote VV, site liaisons to coordinate community outreach, and a memorandum of understanding between all invested parties. A total of 53 community organizations and 725 participants were approached for recruitment. Ultimately, 12 sites and 201 participants were enrolled. Enrollment took 38 months, but our approaches helped successfully recruit a low-income, low-access population. The process took longer than anticipated, and funding constraints prevented certain strategies from being implemented. Recruiting community partners and members for participation in a multi-level, community-based intervention was challenging. Strategies and lessons learned can inform future studies.

The Structure of Young Stellar Systems: Establishing the Initial Conditions for Planet Formation

NASA Technical Reports Server (NTRS)

Blake, Geoffrey A.

2004-01-01

FYO1-FY03 Origins support to the PI had been as part of an effort involving Profs. Blake, van Dishoeck and L.G. Mundy of the University of Maryland. As outlined below, the merging of BIMA+OVRO into the Combined Array for Research in Millimeter Astronomy (CARMA) and our mutual involvement in the Spitzer Legacy Science program now provides a more natural means of continuing the Caltech/Maryland collaboration. In addition, the spectroscopy/radiative transfer programs led by Profs. Blake, Hogerheijde, and van Dishoeck form a more cohesive basis for a single proposal. Students supported by our previous Origins grant have been involved in making some of the first sub-arcsecond resolution images of the morphology and chemistry of individual YSOs at OVRO and BIMA, in the analysis of IR spectra taken by ISO, and in continuing exploratory IR diffraction-limited imaging and spectroscopy at the Keck and VLT observatories. Notable scientific accomplishments in the past grant period include: 1) detecting high density and temperature hot cores in the dynamically accreting envelopes of low mass protostars that contain significant quantities of complex, prebioitc molecules, 2) imaging chemical and isotopic zonation in the outer regions of T Tauri star accretion disks, particularly fractional ionization and D/H studies, 3) acquiring and modeling the first extensive CO v = 1 approaches 0 spectroscopy survey of the terrestrial planet-forming region of circumstellar accretion disks, and 4) optimizing detailed radiative transfer modeling of the molecular and dust emission from YSO envelopes and from comets, including a new parallelized implementation.

Benthic macrofauna data for San Francisco Bay, California, September 1986

USGS Publications Warehouse

Schemel, Laurence E.; Thompson, J.K.; Harmon, J.G.; Yost, B.T.

1995-01-01

Benthic macrofauna were collected during September 1986 to evaluate locations for long-term monitoring stations as part of the U.S. Geological Survey Regional Effects Monitoring Program in San Francisco Bay, California. Three to ten replicate samples were collected with a modified Van Veen sampler (0.05 m2 area) at ten locations. One box core sample (0.06 m2 area) was collected at seven to the ten locations. Six of the box core samples were split into an upper 10 cm sample and a deeper sample before analysis. Macrofauna specimens were identified to the lowest possible taxon, usually genus and species, then counted. An average of 88 percent of the benthic macrofauna specimens were identified to the species level. The fraction identified varied among stations from 54 to 98 percent. Nematodes and oligochaetes accounted for most of the unidentified specimens. Relative to the total number of species identified in five replicates at each location, an average of 90 percent of the species were collected with three replicates. In general, species with high to moderate abundances were present in all replicates, and species collected only after three or more replicates averaged less than one specimen per replicate. Results from the box cores showed that the dominant species were most abundant in the upper 10 cm, the depth of sediment that can be adequately sampled with a modified Van Veen sampler. On the basis of the number of species and their abundances at each location, seven of the ten locations were selected for sampling in the regular program, which began in March 1987.

The Economics of van der Waals Force Engineering

NASA Astrophysics Data System (ADS)

Pinto, Fabrizio

2008-01-01

As micro-electro-mechanical system (MEMS) fabrication continues on an ever-decreasing scale, new technological challenges must be successfully negotiated if Moore's Law is to be an even approximately valid model of the future of device miniaturization. Among the most significant obstacles is the existence of strong surface forces related to quantum mechanical van der Waals interatomic interactions, which rapidly diverge as the distance between any two neutral boundaries decreases. The van der Waals force is a contributing factor in several device failures and limitations, including, for instance, stiction and oscillator non-linearities. In the last decade, however, it has been conclusively shown that van der Waals forces are not just a MEMS limitation but can be engineered in both magnitude and sign so as to enable classes of proprietary inventions which either deliver novel capabilities or improve upon existing ones. The evolution of van der Waals force research from an almost exclusively theoretical field in quantum-electro-dynamics to an enabling nanotechnology discipline represents a useful example of the ongoing paradigm shift from government-centered to private-capital funded R&D in cutting-edge physics leading to potentially profitable products. In this paper, we discuss the reasons van der Waals force engineering may lead to the creation of thriving markets both in the short and medium terms by highlighting technical challenges that can be competitively addressed by this novel approach. We also discuss some notable obstacles to the cultural transformation of the academic research community required for the emergence of a functional van der Waals force engineering industry worldwide.