Sample records for variability analysis heralds

  1. Heralded processes on continuous-variable spaces as quantum maps

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ferreyrol, Franck; Spagnolo, Nicolò; Blandino, Rémi

    2014-12-04

    Heralding processes, which only work when a measurement on a part of the system give the good result, are particularly interesting for continuous-variables. They permit non-Gaussian transformations that are necessary for several continuous-variable quantum information tasks. However if maps and quantum process tomography are commonly used to describe quantum transformations in discrete-variable space, they are much rarer in the continuous-variable domain. Also, no convenient tool for representing maps in a way more adapted to the particularities of continuous variables have yet been explored. In this paper we try to fill this gap by presenting such a tool.

  2. Secure Continuous Variable Teleportation and Einstein-Podolsky-Rosen Steering

    NASA Astrophysics Data System (ADS)

    He, Qiongyi; Rosales-Zárate, Laura; Adesso, Gerardo; Reid, Margaret D.

    2015-10-01

    We investigate the resources needed for secure teleportation of coherent states. We extend continuous variable teleportation to include quantum teleamplification protocols that allow nonunity classical gains and a preamplification or postattenuation of the coherent state. We show that, for arbitrary Gaussian protocols and a significant class of Gaussian resources, two-way steering is required to achieve a teleportation fidelity beyond the no-cloning threshold. This provides an operational connection between Gaussian steerability and secure teleportation. We present practical recipes suggesting that heralded noiseless preamplification may enable high-fidelity heralded teleportation, using minimally entangled yet steerable resources.

  3. Efficient heralding of O-band passively spatial-multiplexed photons for noise-tolerant quantum key distribution.

    PubMed

    Liu, Mao Tong; Lim, Han Chuen

    2014-09-22

    When implementing O-band quantum key distribution on optical fiber transmission lines carrying C-band data traffic, noise photons that arise from spontaneous Raman scattering or insufficient filtering of the classical data channels could cause the quantum bit-error rate to exceed the security threshold. In this case, a photon heralding scheme may be used to reject the uncorrelated noise photons in order to restore the quantum bit-error rate to a low level. However, the secure key rate would suffer unless one uses a heralded photon source with sufficiently high heralding rate and heralding efficiency. In this work we demonstrate a heralded photon source that has a heralding efficiency that is as high as 74.5%. One disadvantage of a typical heralded photon source is that the long deadtime of the heralding detector results in a significant drop in the heralding rate. To counter this problem, we propose a passively spatial-multiplexed configuration at the heralding arm. Using two heralding detectors in this configuration, we obtain an increase in the heralding rate by 37% and a corresponding increase in the heralded photon detection rate by 16%. We transmit the O-band photons over 10 km of noisy optical fiber to observe the relation between quantum bit-error rate and noise-degraded second-order correlation function of the transmitted photons. The effects of afterpulsing when we shorten the deadtime of the heralding detectors are also observed and discussed.

  4. Herald waves of cholera in nineteenth century London.

    PubMed

    Tien, Joseph H; Poinar, Hendrik N; Fisman, David N; Earn, David J D

    2011-05-06

    Deaths from cholera in London, UK, were recorded weekly from 1824 to 1901. Three features of the time series stand out: (i) cholera deaths were strongly seasonal, with peak mortality almost always in the summer, (ii) the only non-summer outbreaks occurred in the spring of 1832, the autumn of 1848 and the winter of 1853, and (iii) extraordinarily severe summer outbreaks occurred in 1832, 1849, 1854 and 1866 (the four 'great' cholera years). The non-summer outbreaks of 1832, 1848 and 1853 appear to have been herald waves of newly invading cholera strains. In addition, a simple mathematical model confirms that a non-summer introduction of a new cholera strain can result in an initial herald wave, followed by a severe outbreak the following summer. Through the analysis of the genomes of nineteenth-century specimens, it may be possible to identify the strains that caused these herald waves and the well-known cholera epidemics that followed.

  5. 32 CFR 507.14 - Controlled heraldic items.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Heraldic Quality Control Program § 507.14 Controlled..., U.S. Army. (d) U.S. Air Force organizational emblems for other than major commands. (e) Hand...

  6. Herald waves of cholera in nineteenth century London

    PubMed Central

    Tien, Joseph H.; Poinar, Hendrik N.; Fisman, David N.; Earn, David J. D.

    2011-01-01

    Deaths from cholera in London, UK, were recorded weekly from 1824 to 1901. Three features of the time series stand out: (i) cholera deaths were strongly seasonal, with peak mortality almost always in the summer, (ii) the only non-summer outbreaks occurred in the spring of 1832, the autumn of 1848 and the winter of 1853, and (iii) extraordinarily severe summer outbreaks occurred in 1832, 1849, 1854 and 1866 (the four ‘great’ cholera years). The non-summer outbreaks of 1832, 1848 and 1853 appear to have been herald waves of newly invading cholera strains. In addition, a simple mathematical model confirms that a non-summer introduction of a new cholera strain can result in an initial herald wave, followed by a severe outbreak the following summer. Through the analysis of the genomes of nineteenth-century specimens, it may be possible to identify the strains that caused these herald waves and the well-known cholera epidemics that followed. PMID:21123253

  7. MHz rate and efficient synchronous heralding of single photons at telecom wavelengths.

    PubMed

    Pomarico, Enrico; Sanguinetti, Bruno; Guerreiro, Thiago; Thew, Rob; Zbinden, Hugo

    2012-10-08

    We report on the realization of a synchronous source of heralded single photons at telecom wavelengths with MHz heralding rates and high heralding efficiency. This source is based on the generation of photon pairs at 810 and 1550 nm via Spontaneous Parametric Down Conversion (SPDC) in a 1 cm periodically poled lithium niobate (PPLN) crystal pumped by a 532 nm pulsed laser. As high rates are fundamental for multi-photon experiments, we show that single telecom photons can be announced at 4.4 MHz rate with 45% heralding efficiency. When we focus only on the optimization of the coupling of the heralded photon, the heralding efficiency can be increased up to 80%. Furthermore, we experimentally observe that group velocity mismatch inside long crystals pumped in a pulsed mode affects the spectrum of the emitted photons and their fibre coupling efficiency. The length of the crystal in this source has been chosen as a trade off between high brightness and high coupling efficiency.

  8. 32 CFR 507.12 - Possession and wearing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Commercial Use of Heraldic Designs § 507.12..., society, or other group of persons without prior approval in writing by the Secretary of the Army or the...

  9. 32 CFR 507.12 - Possession and wearing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Commercial Use of Heraldic Designs § 507.12..., society, or other group of persons without prior approval in writing by the Secretary of the Army or the...

  10. 32 CFR 507.12 - Possession and wearing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Commercial Use of Heraldic Designs § 507.12..., society, or other group of persons without prior approval in writing by the Secretary of the Army or the...

  11. 32 CFR 507.12 - Possession and wearing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Commercial Use of Heraldic Designs § 507.12..., society, or other group of persons without prior approval in writing by the Secretary of the Army or the...

  12. 32 CFR 507.12 - Possession and wearing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Commercial Use of Heraldic Designs § 507.12..., society, or other group of persons without prior approval in writing by the Secretary of the Army or the...

  13. Atom-Resonant Heralded Single Photons by Interaction-Free Measurement

    NASA Astrophysics Data System (ADS)

    Wolfgramm, Florian; de Icaza Astiz, Yannick A.; Beduini, Federica A.; Cerè, Alessandro; Mitchell, Morgan W.

    2011-02-01

    We demonstrate the generation of rubidium-resonant heralded single photons for quantum memories. Photon pairs are created by cavity-enhanced down-conversion and narrowed in bandwidth to 7 MHz with a novel atom-based filter operating by “interaction-free measurement” principles. At least 94% of the heralded photons are atom-resonant as demonstrated by a direct absorption measurement with rubidium vapor. A heralded autocorrelation measurement shows gc(2)(0)=0.040±0.012, i.e., suppression of multiphoton contributions by a factor of 25 relative to a coherent state. The generated heralded photons can readily be used in quantum memories and quantum networks.

  14. The Deglacial to Holocene Paleoceanography of Bering Strait: Results From the SWERUS-C3 Program

    NASA Astrophysics Data System (ADS)

    Jakobsson, M.; Anderson, L. G.; Backman, J.; Barrientos, N.; Björk, G. M.; Coxall, H.; Cronin, T. M.; De Boer, A. M.; Gemery, L.; Jerram, K.; Johansson, C.; Kirchner, N.; Mayer, L. A.; Mörth, C. M.; Nilsson, J.; Noormets, R. R. N. N.; O'Regan, M.; Pearce, C.; Semiletov, I. P.; Stranne, C.

    2017-12-01

    The climate-carbon-cryosphere (C3) interactions in the East Siberian Arctic Ocean and related ocean, river and land areas of the Arctic have been the focus for the SWERUS-C3 Program (Swedish - Russian - US Arctic Ocean Investigation of Climate-Cryosphere-Carbon Interactions). This multi-investigator, multi-disciplinary program was carried out on a two-leg 90-day long expedition in 2014 with Swedish icebreaker Oden. One component of the expedition consisted of geophysical mapping and coring of Herald Canyon, located on the Chukchi Sea shelf north of the Bering Strait in the western Arctic Ocean. Herald Canyon is strategically placed to capture the history of the Pacific-Arctic Ocean connection and related changes in Arctic Ocean paleoceanography. Here we present a summary of key results from analyses of the marine geophysical mapping data and cores collected from Herald Canyon on the shelf and slope that proved to be particularly well suited for paleoceanographic reconstruction. For example, we provide a new age constraint of 11 cal ka BP on sediments from the uppermost slope for the initial flooding of the Bering Land Bridge and reestablishment of the Pacific-Arctic Ocean connection following the last glaciation. This age corresponds to meltwater pulse 1b (MWP1b) known as a post-Younger Dryas warming in many sea level and paleoclimate records. In addition, high late Holocene sedimentation rates that range between about 100 and 300 cm kyr-1, in Herald Canyon permitted paleoceanographic reconstructions of ocean circulation and sea ice cover at centennial scales throughout the late Holocene. Evidence suggests varying influence from inflowing Pacific water into the western Arctic Ocean including some evidence for quasi-cyclic variability in several paleoceanographic parameters, e.g. micropaleontological assemblages, isotope geochemistry and sediment physical properties.

  15. 76 FR 17446 - Wausau Daily Herald Advertising Production Division, a Subsidiary of Gannett Co., Inc.; Wausau...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-29

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-75,090] Wausau Daily Herald Advertising Production Division, a Subsidiary of Gannett Co., Inc.; Wausau, WI; Notice of Affirmative... workers of Wausau Daily Herald, Advertising Production Division, a subsidiary of Gannett Co., Inc., Wausau...

  16. 32 CFR 507.11 - Reproduction of designs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Commercial Use of Heraldic Designs § 507.11 Reproduction of designs. (a) The photographing, printing, or, in any manner making or executing any engraving... 32 National Defense 3 2012-07-01 2009-07-01 true Reproduction of designs. 507.11 Section 507.11...

  17. 32 CFR 507.11 - Reproduction of designs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Commercial Use of Heraldic Designs § 507.11 Reproduction of designs. (a) The photographing, printing, or, in any manner making or executing any engraving... 32 National Defense 3 2013-07-01 2013-07-01 false Reproduction of designs. 507.11 Section 507.11...

  18. 32 CFR 507.11 - Reproduction of designs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Commercial Use of Heraldic Designs § 507.11 Reproduction of designs. (a) The photographing, printing, or, in any manner making or executing any engraving... 32 National Defense 3 2014-07-01 2014-07-01 false Reproduction of designs. 507.11 Section 507.11...

  19. 32 CFR 507.11 - Reproduction of designs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Commercial Use of Heraldic Designs § 507.11 Reproduction of designs. (a) The photographing, printing, or, in any manner making or executing any engraving... 32 National Defense 3 2010-07-01 2010-07-01 true Reproduction of designs. 507.11 Section 507.11...

  20. 32 CFR 507.11 - Reproduction of designs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Commercial Use of Heraldic Designs § 507.11 Reproduction of designs. (a) The photographing, printing, or, in any manner making or executing any engraving... 32 National Defense 3 2011-07-01 2009-07-01 true Reproduction of designs. 507.11 Section 507.11...

  1. 32 CFR 507.17 - Procurement and wear of heraldic items.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... controlled heraldic items, when authorized by local procurement procedures, may forward a sample insignia to... 32 National Defense 3 2010-07-01 2010-07-01 true Procurement and wear of heraldic items. 507.17... AUTHORITIES AND PUBLIC RELATIONS MANUFACTURE AND SALE OF DECORATIONS, MEDALS, BADGES, INSIGNIA, COMMERCIAL USE...

  2. 49. Copy Photograph, L.A. Herald Examiner, July e, 1936 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. Copy Photograph, L.A. Herald Examiner, July e, 1936 (original print in the Regional Cultural History Collection, University of Southern California, Herald Examiner Photograph Collection) PASSENGER TUNNEL UNDER CONSTRUCTION, LOOKING EAST - Los Angeles Union Passenger Terminal, Tracks & Shed, 800 North Alameda Street, Los Angeles, Los Angeles County, CA

  3. On-chip III-V monolithic integration of heralded single photon sources and beamsplitters

    NASA Astrophysics Data System (ADS)

    Belhassen, J.; Baboux, F.; Yao, Q.; Amanti, M.; Favero, I.; Lemaître, A.; Kolthammer, W. S.; Walmsley, I. A.; Ducci, S.

    2018-02-01

    We demonstrate a monolithic III-V photonic circuit combining a heralded single photon source with a beamsplitter, at room temperature and telecom wavelength. Pulsed parametric down-conversion in an AlGaAs waveguide generates counterpropagating photons, one of which is used to herald the injection of its twin into the beamsplitter. We use this configuration to implement an integrated Hanbury-Brown and Twiss experiment, yielding a heralded second-order correlation gher(2 )(0 )=0.10 ±0.02 that confirms single-photon operation. The demonstrated generation and manipulation of quantum states on a single III-V semiconductor chip opens promising avenues towards real-world applications in quantum information.

  4. Heralded quantum controlled-phase gates with dissipative dynamics in macroscopically distant resonators

    NASA Astrophysics Data System (ADS)

    Qin, Wei; Wang, Xin; Miranowicz, Adam; Zhong, Zhirong; Nori, Franco

    2017-07-01

    Heralded near-deterministic multiqubit controlled-phase gates with integrated error detection have recently been proposed by Borregaard et al. [Phys. Rev. Lett. 114, 110502 (2015), 10.1103/PhysRevLett.114.110502]. This protocol is based on a single four-level atom (a heralding quartit) and N three-level atoms (operational qutrits) coupled to a single-resonator mode acting as a cavity bus. Here we generalize this method for two distant resonators without the cavity bus between the heralding and operational atoms. Specifically, we analyze the two-qubit controlled-Z gate and its multiqubit-controlled generalization (i.e., a Toffoli-like gate) acting on the two-lowest levels of N qutrits inside one resonator, with their successful actions being heralded by an auxiliary microwave-driven quartit inside the other resonator. Moreover, we propose a circuit-quantum-electrodynamics realization of the protocol with flux and phase qudits in linearly coupled transmission-line resonators with dissipation. These methods offer a quadratic fidelity improvement compared to cavity-assisted deterministic gates.

  5. Quantum Communication Systems

    DTIC Science & Technology

    2008-03-15

    numbers make the observation of non -Poissonian features easier, which calls for higher pump power and better mode matching of the pump beam , more...heralded two-photon NOON states, we rely on the local photon- bunching effect of two heralded single photons at a beam splitter , as sketched in Fig. 1. Two...heralded single photons are sent to separate input ports of a 50:50 beam splitter (BS1). The photons bunch at the beam splitter , exiting together from

  6. Late Holocene sea ice conditions in Herald Canyon, Chukchi Sea

    NASA Astrophysics Data System (ADS)

    Pearce, C.; O'Regan, M.; Rattray, J. E.; Hutchinson, D. K.; Cronin, T. M.; Gemery, L.; Barrientos, N.; Coxall, H.; Smittenberg, R.; Semiletov, I. P.; Jakobsson, M.

    2017-12-01

    Sea ice in the Arctic Ocean has been in steady decline in recent decades and, based on satellite data, the retreat is most pronounced in the Chukchi and Beaufort seas. Historical observations suggest that the recent changes were unprecedented during the last 150 years, but for a longer time perspective, we rely on the geological record. For this study, we analyzed sediment samples from two piston cores from Herald Canyon in the Chukchi Sea, collected during the 2014 SWERUS-C3 Arctic Ocean Expedition. The Herald Canyon is a local depression across the Chukchi Shelf, and acts as one of the main pathways for Pacific Water to the Arctic Ocean after entering through the narrow and shallow Bering Strait. The study site lies at the modern-day seasonal sea ice minimum edge, and is thus an ideal location for the reconstruction of past sea ice variability. Both sediment cores contain late Holocene deposits characterized by high sediment accumulation rates (100-300 cm/kyr). Core 2-PC1 from the shallow canyon flank (57 m water depth) is 8 meter long and extends back to 4200 cal yrs BP, while the upper 3 meters of Core 4-PC1 from the central canyon (120 mwd) cover the last 3000 years. The chronologies of the cores are based on radiocarbon dates and the 3.6 ka Aniakchak CFE II tephra, which is used as an absolute age marker to calculate the marine radiocarbon reservoir age. Analysis of biomarkers for sea ice and surface water productivity indicate stable sea ice conditions throughout the entire late Holocene, ending with an abrupt increase of phytoplankton sterols in the very top of both sediment sequences. The shift is accompanied by a sudden increase in coarse sediments (> 125 µm) and a minor change in δ13Corg. We interpret this transition in the top sediments as a community turnover in primary producers from sea ice to open water biota. Most importantly, our results indicate that the ongoing rapid ice retreat in the Chukchi Sea of recent decades was unprecedented during the last 4000 years.

  7. Heralding efficiency and correlated-mode coupling of near-IR fiber-coupled photon pairs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dixon, P. Ben; Rosenberg, Danna; Stelmakh, Veronika

    We report on a systematic experimental study of heralding efficiency and generation rate of telecom-band infrared photon pairs generated by spontaneous parametric down-conversion and coupled to single mode optical fibers. We define the correlated-mode coupling efficiency--an inherent source efficiency--and explain its relation to heralding efficiency. For our experiment, we developed a reconfigurable computer controlled pump-beam and collection-mode optical apparatus which we used to measure the generation rate and correlated-mode coupling efficiency. The use of low-noise, high-efficiency superconducting-nanowire single-photon-detectors in this setup allowed us to explore focus configurations with low overall photon flux. The measured data agree well with theory andmore » we demonstrated a correlated-mode coupling efficiency of 97%±2%, which is the highest efficiency yet achieved for this type of system. These results confirm theoretical treatments and demonstrate that very high overall heralding efficiencies can, in principle, be achieved in quantum optical systems. We expect that these results and techniques will be widely incorporated into future systems that require, or benefit from, a high heralding efficiency.« less

  8. Heralding efficiency and correlated-mode coupling of near-IR fiber-coupled photon pairs

    DOE PAGES

    Dixon, P. Ben; Rosenberg, Danna; Stelmakh, Veronika; ...

    2014-10-06

    We report on a systematic experimental study of heralding efficiency and generation rate of telecom-band infrared photon pairs generated by spontaneous parametric down-conversion and coupled to single mode optical fibers. We define the correlated-mode coupling efficiency--an inherent source efficiency--and explain its relation to heralding efficiency. For our experiment, we developed a reconfigurable computer controlled pump-beam and collection-mode optical apparatus which we used to measure the generation rate and correlated-mode coupling efficiency. The use of low-noise, high-efficiency superconducting-nanowire single-photon-detectors in this setup allowed us to explore focus configurations with low overall photon flux. The measured data agree well with theory andmore » we demonstrated a correlated-mode coupling efficiency of 97%±2%, which is the highest efficiency yet achieved for this type of system. These results confirm theoretical treatments and demonstrate that very high overall heralding efficiencies can, in principle, be achieved in quantum optical systems. We expect that these results and techniques will be widely incorporated into future systems that require, or benefit from, a high heralding efficiency.« less

  9. Improving the maximum transmission distance of continuous-variable quantum key distribution using a noiseless amplifier

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blandino, Rémi; Etesse, Jean; Grangier, Philippe

    2014-12-04

    We show that the maximum transmission distance of continuous-variable quantum key distribution in presence of a Gaussian noisy lossy channel can be arbitrarily increased using a heralded noiseless linear amplifier. We explicitly consider a protocol using amplitude and phase modulated coherent states with reverse reconciliation. Assuming that the secret key rate drops to zero for a line transmittance T{sub lim}, we find that a noiseless amplifier with amplitude gain g can improve this value to T{sub lim}/g{sup 2}, corresponding to an increase in distance proportional to log g. We also show that the tolerance against noise is increased.

  10. Processable English: The Theory Behind the PENG System

    DTIC Science & Technology

    2009-06-01

    implicit - is often buried amongst masses of irrelevant data. Heralding from unstructured sources such as natural language documents, email, audio ...estimation and prediction, data-mining, social network analysis, and semantic search and visualisation . This report describes the theoretical

  11. 76 FR 20553 - Changes in Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... 170480 (10-05-2793P). 30, 2010, The Saas, Mayor, Village of Northwest Herald. Huntley, 10987 Main Street... 170480 (10-05-2799P). 23, 2010, The Saas, Mayor, Village of Northwest Herald. Huntley, 10987 Main Street...

  12. Integrated spatial multiplexing of heralded single-photon sources

    PubMed Central

    Collins, M.J.; Xiong, C.; Rey, I.H.; Vo, T.D.; He, J.; Shahnia, S.; Reardon, C.; Krauss, T.F.; Steel, M.J.; Clark, A.S.; Eggleton, B.J.

    2013-01-01

    The non-deterministic nature of photon sources is a key limitation for single-photon quantum processors. Spatial multiplexing overcomes this by enhancing the heralded single-photon yield without enhancing the output noise. Here the intrinsic statistical limit of an individual source is surpassed by spatially multiplexing two monolithic silicon-based correlated photon pair sources in the telecommunications band, demonstrating a 62.4% increase in the heralded single-photon output without an increase in unwanted multipair generation. We further demonstrate the scalability of this scheme by multiplexing photons generated in two waveguides pumped via an integrated coupler with a 63.1% increase in the heralded photon rate. This demonstration paves the way for a scalable architecture for multiplexing many photon sources in a compact integrated platform and achieving efficient two-photon interference, required at the core of optical quantum computing and quantum communication protocols. PMID:24107840

  13. Highly efficient heralded single-photon source for telecom wavelengths based on a PPLN waveguide.

    PubMed

    Bock, Matthias; Lenhard, Andreas; Chunnilall, Christopher; Becher, Christoph

    2016-10-17

    We present the realization of a highly efficient photon pair source based on spontaneous parametric downconversion (SPDC) in a periodically poled lithium niobate (PPLN) ridge waveguide. The source is suitable for long distance quantum communication applications as the photon pairs are located at the centers of the telecommunication O- and C- band at 1312 nm and 1557 nm. The high efficiency is confirmed by a conversion efficiency of 4 × 10-6 - which is to our knowledge among the highest conversion efficiencies reported so far - and a heralding efficiency of 64.1 ± 2.1%. The heralded single-photon properties are confirmed by the measurement of the photon statistics with a Click/No-Click method as well as the heralded g(2)-function. A minimum value for g(2)(0) of 0.001 ± 0.0003 indicating clear antibunching has been observed.

  14. On-chip low loss heralded source of pure single photons.

    PubMed

    Spring, Justin B; Salter, Patrick S; Metcalf, Benjamin J; Humphreys, Peter C; Moore, Merritt; Thomas-Peter, Nicholas; Barbieri, Marco; Jin, Xian-Min; Langford, Nathan K; Kolthammer, W Steven; Booth, Martin J; Walmsley, Ian A

    2013-06-03

    A key obstacle to the experimental realization of many photonic quantum-enhanced technologies is the lack of low-loss sources of single photons in pure quantum states. We demonstrate a promising solution: generation of heralded single photons in a silica photonic chip by spontaneous four-wave mixing. A heralding efficiency of 40%, corresponding to a preparation efficiency of 80% accounting for detector performance, is achieved due to efficient coupling of the low-loss source to optical fibers. A single photon purity of 0.86 is measured from the source number statistics without narrow spectral filtering, and confirmed by direct measurement of the joint spectral intensity. We calculate that similar high-heralded-purity output can be obtained from visible to telecom spectral regions using this approach. On-chip silica sources can have immediate application in a wide range of single-photon quantum optics applications which employ silica photonics.

  15. Quantum storage of heralded polarization qubits in birefringent and anisotropically absorbing materials.

    PubMed

    Clausen, Christoph; Bussières, Félix; Afzelius, Mikael; Gisin, Nicolas

    2012-05-11

    Storage of quantum information encoded into heralded single photons is an essential constituent of long-distance quantum communication based on quantum repeaters and of optical quantum information processing. The storage of photonic polarization qubits is, however, difficult because many materials are birefringent and have polarization-dependent absorption. Here we present a simple scheme that eliminates these polarization effects, and we demonstrate it by storing heralded polarization qubits into a solid-state quantum memory. The quantum memory is implemented with a biaxial yttrium orthosilicate (Y2SiO5) crystal doped with rare-earth ions. Heralded single photons generated from a filtered spontaneous parametric down-conversion source are stored, and quantum state tomography of the retrieved polarization state reveals an average fidelity of 97.5±0.4%, which is significantly higher than what is achievable with a measure-and-prepare strategy.

  16. 76 FR 52930 - Availability of Decisions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-24

    ... County, Colorado. San Juan National Forest, Colorado Forest Supervisor Decisions Durango Herald, published daily in Durango, La Plata County, Colorado. District Ranger Decisions Durango Herald, published daily in Durango, La Plata County, Colorado. White River National Forest, Colorado Forest Supervisor...

  17. Herald : field operational test evaluation final report

    DOT National Transportation Integrated Search

    2000-09-01

    The Herald Field Operational Test (FOT) tested AM radio as a low-cost way to broadcast traveler information in rural areas. It tested the feasibility of broadcasting data on the inaudible portion of an existing AM broadcast. Two systems were tested, ...

  18. Herald Field Operation Test Evaluation : Final Report

    DOT National Transportation Integrated Search

    2000-09-01

    The Herald Field Operational Test (FOT) tested AM radio as a low-cost way to broadcast traveler information in rural areas. It tested the feasibility of broadcasting data on the inaudible portion of an existing AM broadcast. Two systems were tested, ...

  19. 78 FR 12290 - Annual List of Newspapers Used for Publication of Legal Notice of Decisions Appealable Under 36...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-22

    ... Decisions Durango Herald, published daily in Durango, La Plata County, Colorado. Notice by District Rangers of Availability for Comment and Decisions Durango Herald, published daily in Durango, La Plata County...

  20. Realizing the measure-device-independent quantum-key-distribution with passive heralded-single photon sources

    PubMed Central

    Wang, Qin; Zhou, Xing-Yu; Guo, Guang-Can

    2016-01-01

    In this paper, we put forward a new approach towards realizing measurement-device-independent quantum key distribution with passive heralded single-photon sources. In this approach, both Alice and Bob prepare the parametric down-conversion source, where the heralding photons are labeled according to different types of clicks from the local detectors, and the heralded ones can correspondingly be marked with different tags at the receiver’s side. Then one can obtain four sets of data through using only one-intensity of pump light by observing different kinds of clicks of local detectors. By employing the newest formulae to do parameter estimation, we could achieve very precise prediction for the two-single-photon pulse contribution. Furthermore, by carrying out corresponding numerical simulations, we compare the new method with other practical schemes of measurement-device-independent quantum key distribution. We demonstrate that our new proposed passive scheme can exhibit remarkable improvement over the conventional three-intensity decoy-state measurement-device-independent quantum key distribution with either heralded single-photon sources or weak coherent sources. Besides, it does not need intensity modulation and can thus diminish source-error defects existing in several other active decoy-state methods. Therefore, if taking intensity modulating errors into account, our new method will show even more brilliant performance. PMID:27759085

  1. Evolution of the hemagglutinin expressed by human influenza A(H1N1)pdm09 and A(H3N2) viruses circulating between 2008-2009 and 2013-2014 in Germany.

    PubMed

    Wedde, Marianne; Biere, Barbara; Wolff, Thorsten; Schweiger, Brunhilde

    2015-10-01

    This report describes the evolution of the influenza A(H1N1)pdm09 and A(H3N2) viruses circulating in Germany between 2008-2009 and 2013-2014. The phylogenetic analysis of the hemagglutinin (HA) genes of both subtypes revealed similar evolution of the HA variants that were also seen worldwide with minor exceptions. The analysis showed seven distinct HA clades for A(H1N1)pdm09 and six HA clades for A(H3N2) viruses. Herald strains of both subtypes appeared sporadically since 2008-2009. Regarding A(H1N1)pdm09, herald strains of HA clade 3 and 4 were detected late in the 2009-2010 season. With respect to A(H3N2), we found herald strains of HA clade 3, 4 and 7 between 2009 and 2012. Those herald strains were predominantly seen for minor and not for major HA clades. Generally, amino acid substitutions were most frequently found in the globular domain, including substitutions near the antigenic sites or the receptor binding site. Differences between both influenza A subtypes were seen with respect to the position of the indicated substitutions in the HA. For A(H1N1)pdm09 viruses, we found more substitutions in the stem region than in the antigenic sites. In contrast, in A(H3N2) viruses most changes were identified in the major antigenic sites and five changes of potential glycosylation sites were identified in the head of the HA monomer. Interestingly, we found in seasons with less influenza activity a relatively high increase of substitutions in the head of the HA in both subtypes. This might be explained by the fact that mutations under negative selection are subsequently compensated by secondary mutations to restore important functions e.g. receptor binding properties. A better knowledge of basic evolution strategies of influenza viruses will contribute to the refinement of predictive mathematical models for identifying novel antigenic drift variants. Copyright © 2015 Elsevier GmbH. All rights reserved.

  2. 32 CFR 507.6 - Authority to manufacture.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Authority to manufacture. 507.6 Section 507.6... PUBLIC RELATIONS MANUFACTURE AND SALE OF DECORATIONS, MEDALS, BADGES, INSIGNIA, COMMERCIAL USE OF HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Manufacture and Sale of Decorations, Medals, Badges...

  3. High-Efficiency Plug-and-Play Source of Heralded Single Photons

    NASA Astrophysics Data System (ADS)

    Montaut, Nicola; Sansoni, Linda; Meyer-Scott, Evan; Ricken, Raimund; Quiring, Viktor; Herrmann, Harald; Silberhorn, Christine

    2017-08-01

    Reliable generation of single photons is of key importance for fundamental physical experiments and to demonstrate quantum protocols. Waveguide-based photon-pair sources have shown great promise in this regard due to their large spectral tunability, high generation rates, and long temporal coherence of the photon wave packet. However, integrating such sources with fiber-optic networks often results in a strong degradation of performance. We answer this challenge by presenting an alignment-free source of photon pairs in the telecommunications band that maintains heralding efficiency >50 % even after fiber pigtailing, photon separation, and pump suppression. The source combines this outstanding performance in heralding efficiency with a compact, stable, and easy-to-use "plug-and-play" package: one simply connects a laser to the input and detectors to the output, and the source is ready to use. This high performance can be achieved even outside the lab without the need for alignment which makes the source extremely useful for any experiment or demonstration needing heralded single photons.

  4. X-ray-generated heralded macroscopical quantum entanglement of two nuclear ensembles.

    PubMed

    Liao, Wen-Te; Keitel, Christoph H; Pálffy, Adriana

    2016-09-19

    Heralded entanglement between macroscopical samples is an important resource for present quantum technology protocols, allowing quantum communication over large distances. In such protocols, optical photons are typically used as information and entanglement carriers between macroscopic quantum memories placed in remote locations. Here we investigate theoretically a new implementation which employs more robust x-ray quanta to generate heralded entanglement between two crystal-hosted macroscopical nuclear ensembles. Mössbauer nuclei in the two crystals interact collectively with an x-ray spontaneous parametric down conversion photon that generates heralded macroscopical entanglement with coherence times of approximately 100 ns at room temperature. The quantum phase between the entangled crystals can be conveniently manipulated by magnetic field rotations at the samples. The inherent long nuclear coherence times allow also for mechanical manipulations of the samples, for instance to check the stability of entanglement in the x-ray setup. Our results pave the way for first quantum communication protocols that use x-ray qubits.

  5. 32 CFR 507.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... military decorations, medals, badges, and insignia. It also establishes the Heraldic Item Quality Control Program to improve the appearance of the Army and Air Force by controlling the quality of heraldic items... QUALITY CONTROL PROGRAM Introduction § 507.1 Purpose. This part prescribes the Department of the Army and...

  6. "USA Today": Comparative Analysis with Two National and Two Los Angeles Daily Newspapers. Research Bulletin.

    ERIC Educational Resources Information Center

    Ames, Steve; And Others

    Sections of the newspaper "USA Today" were compared with corresponding sections of four major newspapers--the "New York Times," the "Wall Street Journal," the "Los Angeles Herald Examiner," and the "Los Angeles Times"--to determine what editorial components made "USA Today" different and…

  7. 32 CFR 507.9 - Articles not authorized for manufacture or sale.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Articles not authorized for manufacture or sale... CIVIL AUTHORITIES AND PUBLIC RELATIONS MANUFACTURE AND SALE OF DECORATIONS, MEDALS, BADGES, INSIGNIA, COMMERCIAL USE OF HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Manufacture and Sale of Decorations...

  8. 32 CFR 507.8 - Articles authorized for manufacture and sale.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Articles authorized for manufacture and sale. 507... CIVIL AUTHORITIES AND PUBLIC RELATIONS MANUFACTURE AND SALE OF DECORATIONS, MEDALS, BADGES, INSIGNIA, COMMERCIAL USE OF HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Manufacture and Sale of Decorations...

  9. 32 CFR 507.3 - Explanation of abbreviations and terms.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OF HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM Introduction § 507.3 Explanation of... times actual size, showing placement of stitches, color and size of yarn and number of stitches. (2... items worn on the uniform to indicate unit, skill, branch, award or identification and a design has been...

  10. 32 CFR 507.10 - Incorporation of designs or likenesses of approved designs in commercial articles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... DECORATIONS, MEDALS, BADGES, INSIGNIA, COMMERCIAL USE OF HERALDIC DESIGNS AND HERALDIC QUALITY CONTROL PROGRAM... organizational insignia may be incorporated in articles manufactured for sale provided that permission has been... the coat of arms, crest, seal and organizational emblems. Such permission will be in writing...

  11. 76 FR 46854 - Wausau Daily Herald, Advertising Production Division, a Subsidiary of Gannett Co., Inc.,Wausau...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ..., Advertising Production Division, a Subsidiary of Gannett Co., Inc.,Wausau, WI; Notice of Negative...) applicable to workers and former workers of Wausau Daily Herald, Advertising Production Division, a... information revealed that 2AdPro (an advertising firm located in India) handled an insignificant amount of...

  12. 78 FR 11138 - Annual List of Newspapers Used for Publication of Legal Notice of Decisions for the Rocky...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ... Availability for Comment and Decisions Durango Herald, published daily in Durango, La Plata County, Colorado. Notice by District Rangers of Availability for Comment and Decisions Durango Herald, published daily in Durango, La Plata County, Colorado. White River National Forest, Colorado Notice by Forest Supervisor of...

  13. Workplace ESL Literacy Program of the Los Angeles Herald Examiner Newspaper.

    ERIC Educational Resources Information Center

    Herald Examiner, Los Angeles, CA.

    This packet of materials from the Los Angeles Herald Examiner's English-as-a-Second-Language (ESL) workplace literacy program, defunct since the newspaper's closing, contains the following items: an overview of the program; a list of units and subunits; two sample lesson plans; teacher guidelines about evaluation and progress; lists of specific…

  14. Critical Consciousness: A Critique and Critical Analysis of the Literature

    ERIC Educational Resources Information Center

    Jemal, Alexis

    2017-01-01

    The education system has been heralded as a tool of liberation and simultaneously critiqued as a tool of social control to maintain the oppressive status quo. Critical consciousness (CC), developed by the Brazilian educator, Paulo Freire, advanced an educational pedagogy to liberate the masses from systemic inequity maintained and perpetuated by…

  15. Status on Trial: Social Characteristics and Influence in the Jury Room

    ERIC Educational Resources Information Center

    York, Erin; Cornwell, Benjamin

    2006-01-01

    The American jury is heralded as an institution that is simultaneously representative and egalitarian. However, jury studies conducted 50 years ago found that white, upper-class men dominate jury deliberations, presumably due to their higher status outside of the jury room. Logistic regression analysis of dyadic influence inside the jury room…

  16. E-Learning: A Movement Coming of Age?

    ERIC Educational Resources Information Center

    Reindl, Travis

    2005-01-01

    Few phenomena in recent history have generated investment, debate, and analysis as online/e-learning. Whether by Internet, video network, or other means, online course and program delivery has been heralded--and dismissed--as a vehicle for revolutionizing teaching and learning in higher education. However, after about a decade of start-ups,…

  17. Genome-wide analysis of multiethnic cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

    PubMed Central

    Vitart, Veronique; Nag, Abhishek; Hewitt, Alex W; Höhn, René; Venturini, Cristina; Mirshahi, Alireza; Ramdas, Wishal D.; Thorleifsson, Gudmar; Vithana, Eranga; Khor, Chiea-Chuen; Stefansson, Arni B; Liao, Jiemin; Haines, Jonathan L; Amin, Najaf; Wang, Ya Xing; Wild, Philipp S; Ozel, Ayse B; Li, Jun Z; Fleck, Brian W; Zeller, Tanja; Staffieri, Sandra E; Teo, Yik-Ying; Cuellar-Partida, Gabriel; Luo, Xiaoyan; Allingham, R Rand; Richards, Julia E; Senft, Andrea; Karssen, Lennart C; Zheng, Yingfeng; Bellenguez, Céline; Xu, Liang; Iglesias, Adriana I; Wilson, James F; Kang, Jae H; van Leeuwen, Elisabeth M; Jonsson, Vesteinn; Thorsteinsdottir, Unnur; Despriet, Dominiek D.G.; Ennis, Sarah; Moroi, Sayoko E; Martin, Nicholas G; Jansonius, Nomdo M; Yazar, Seyhan; Tai, E-Shyong; Amouyel, Philippe; Kirwan, James; van Koolwijk, Leonieke M.E.; Hauser, Michael A; Jonasson, Fridbert; Leo, Paul; Loomis, Stephanie J; Fogarty, Rhys; Rivadeneira, Fernando; Kearns, Lisa; Lackner, Karl J; de Jong, Paulus T.V.M.; Simpson, Claire L; Pennell, Craig E; Oostra, Ben A; Uitterlinden, André G; Saw, Seang-Mei; Lotery, Andrew J; Bailey-Wilson, Joan E; Hofman, Albert; Vingerling, Johannes R; Maubaret, Cécilia; Pfeiffer, Norbert; Wolfs, Roger C.W.; Lemij, Hans G; Young, Terri L; Pasquale, Louis R; Delcourt, Cécile; Spector, Timothy D; Klaver, Caroline C.W.; Small, Kerrin S; Burdon, Kathryn P; Stefansson, Kari; Wong, Tien-Yin; Viswanathan, Ananth; Mackey, David A; Craig, Jamie E; Wiggs, Janey L; van Duijn, Cornelia M; Hammond, Christopher J; Aung, Tin

    2014-01-01

    Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma and IOP variability may herald glaucomatous development or progression. We report the results of a genome-wide association study meta-analysis of 18 population cohorts from the International Glaucoma Genetics Consortium (IGGC), comprising 35,296 multiethnic participants for IOP. We confirm genetic association of known loci for IOP and primary open angle glaucoma (POAG) and identify four new IOP loci located on chromosome 3q25.31 within the FNDC3B gene (p=4.19×10−08 for rs6445055), two on chromosome 9 (p=2.80×10−11 for rs2472493 near ABCA1 and p=6.39×10−11 for rs8176693 within ABO) and one on chromosome 11p11.2 (best p=1.04×10−11 for rs747782). Separate meta-analyses of four independent POAG cohorts, totaling 4,284 cases and 95,560 controls, show that three of these IOP loci are also associated with POAG. PMID:25173106

  18. Early Child-Care and Educational Policies for the Developing World: The Brazilian Case

    ERIC Educational Resources Information Center

    Rosemberg, Fulvia

    2004-01-01

    This article intends to show that contemporary proposals for early child-care and education (ECCE), typical of the modern process of neo-liberal policies, have been familiar to developing countries since the 1960s. Their heralds continue to announce the same news; they have just changed their clothes. These heralds are the international…

  19. An Application of Quadratic Functions to Australian Government Policy on Funding Schools

    ERIC Educational Resources Information Center

    Nillsen, Rodney

    2007-01-01

    In the "Sydney Morning Herald" of 23 March 2005, Ross Gittins argued that the funding arrangements for private schools positively encourage parents to move their children from the state system. The then Federal Minister for Education, Dr Brendan Nelson, in a letter to the "Herald" of 25-27 March, responded by saying that 68% of…

  20. Photon statistics and polarization correlations at telecommunications wavelengths from a warm atomic ensemble.

    PubMed

    Willis, R T; Becerra, F E; Orozco, L A; Rolston, S L

    2011-07-18

    We present measurements of the polarization correlation and photon statistics of photon pairs that emerge from a laser-pumped warm rubidium vapor cell. The photon pairs occur at 780 nm and 1367 nm and are polarization entangled. We measure the autocorrelation of each of the generated fields as well as the cross-correlation function, and observe a strong violation of the two-beam Cauchy-Schwartz inequality. We evaluate the performance of the system as source of heralded single photons at a telecommunication wavelength. We measure the heralded autocorrelation and see that coincidences are suppressed by a factor of ≈ 20 from a Poissonian source at a generation rate of 1500 s(-1), a heralding efficiency of 10%, and a narrow spectral width.

  1. The Founding of the Penny Press: Nothing New under "The Sun,""The Herald," or "The Tribune."

    ERIC Educational Resources Information Center

    Williams, Julie Hedgepeth

    While the founders of the penny press did not set out to establish a truer form of journalism, they did popularize both low prices for newspapers and newspaper economics based on sales instead of political party backing. The history of "The Sun,""The Herald," and "The Tribune" disprove the idea (advanced by journalism…

  2. Hong-Ou-Mandel Interference Between Triggered And Heralded Single Photons From Separate Atomic Systems

    NASA Astrophysics Data System (ADS)

    Cere, Alessandro; Leong, Victor; Kaur Gulati, Gurpreet; Srivathsan, Bharath; Kosen, Sandoko; Kurtsiefer, Christian

    2015-05-01

    The realization of quantum networks and long distance quantum communication rely on the capability of generating entanglement between separated nodes. We demonstrate the compatibility of two different sources of single photons: a single atom and four-wave mixing in a cold cloud of atoms. The four-wave mixing process in a cloud of cold 87Rb generates photon pairs. The cascade level scheme used ensures the generation of heralded single photons with exponentially decaying temporal envelope. The temporal shape of the heralding photons matches the shape of photons emitted by spontaneous decay but for the shorter coherence time A single 87Rb atom is trapped in an far-off-resonance optical dipole trap and can be excited with high probability using a short (~3 ns) intense pulse of resonant light, emitting a single photon by spontaneous decay. A large numerical aperture lens collects ~4% of the total fluorescence. The heralded and the triggered photons are launched into a Houng-Ou-Mandel interferometer: a symmetrical beam-splitter with outputs connected to single photon detectors. Scanning the relative delay between the two sources we observe the HOM dip with a maximum visibility of 70 +/-4%.

  3. Measurement-device-independent quantum key distribution with multiple crystal heralded source with post-selection

    NASA Astrophysics Data System (ADS)

    Chen, Dong; Shang-Hong, Zhao; MengYi, Deng

    2018-03-01

    The multiple crystal heralded source with post-selection (MHPS), originally introduced to improve the single-photon character of the heralded source, has specific applications for quantum information protocols. In this paper, by combining decoy-state measurement-device-independent quantum key distribution (MDI-QKD) with spontaneous parametric downconversion process, we present a modified MDI-QKD scheme with MHPS where two architectures are proposed corresponding to symmetric scheme and asymmetric scheme. The symmetric scheme, which linked by photon switches in a log-tree structure, is adopted to overcome the limitation of the current low efficiency of m-to-1 optical switches. The asymmetric scheme, which shows a chained structure, is used to cope with the scalability issue with increase in the number of crystals suffered in symmetric scheme. The numerical simulations show that our modified scheme has apparent advances both in transmission distance and key generation rate compared to the original MDI-QKD with weak coherent source and traditional heralded source with post-selection. Furthermore, the recent advances in integrated photonics suggest that if built into a single chip, the MHPS might be a practical alternative source in quantum key distribution tasks requiring single photons to work.

  4. Advocacy Groups and the Discourse of Teacher Policy Reform: An Analysis of Policy Narratives

    ERIC Educational Resources Information Center

    Harrison, Christopher

    2017-01-01

    In recent years, several states have engaged in significant action surrounding a key policy area-- teacher policy reform. In Florida, for example, the passage of Senate Bill (SB) 736, the Student Success Act, heralded substantial shifts in the boundaries defining the profession of teaching in the state. Through SB 736 and its unsuccessful…

  5. Arctic pathways of Pacific Water: Arctic Ocean Model Intercomparison experiments.

    PubMed

    Aksenov, Yevgeny; Karcher, Michael; Proshutinsky, Andrey; Gerdes, Rüdiger; de Cuevas, Beverly; Golubeva, Elena; Kauker, Frank; Nguyen, An T; Platov, Gennady A; Wadley, Martin; Watanabe, Eiji; Coward, Andrew C; Nurser, A J George

    2016-01-01

    Pacific Water (PW) enters the Arctic Ocean through Bering Strait and brings in heat, fresh water, and nutrients from the northern Bering Sea. The circulation of PW in the central Arctic Ocean is only partially understood due to the lack of observations. In this paper, pathways of PW are investigated using simulations with six state-of-the art regional and global Ocean General Circulation Models (OGCMs). In the simulations, PW is tracked by a passive tracer, released in Bering Strait. Simulated PW spreads from the Bering Strait region in three major branches. One of them starts in the Barrow Canyon, bringing PW along the continental slope of Alaska into the Canadian Straits and then into Baffin Bay. The second begins in the vicinity of the Herald Canyon and transports PW along the continental slope of the East Siberian Sea into the Transpolar Drift, and then through Fram Strait and the Greenland Sea. The third branch begins near the Herald Shoal and the central Chukchi shelf and brings PW into the Beaufort Gyre. In the models, the wind, acting via Ekman pumping, drives the seasonal and interannual variability of PW in the Canadian Basin of the Arctic Ocean. The wind affects the simulated PW pathways by changing the vertical shear of the relative vorticity of the ocean flow in the Canada Basin.

  6. Sequential Modular Position and Momentum Measurements of a Trapped Ion Mechanical Oscillator

    NASA Astrophysics Data System (ADS)

    Flühmann, C.; Negnevitsky, V.; Marinelli, M.; Home, J. P.

    2018-04-01

    The noncommutativity of position and momentum observables is a hallmark feature of quantum physics. However, this incompatibility does not extend to observables that are periodic in these base variables. Such modular-variable observables have been suggested as tools for fault-tolerant quantum computing and enhanced quantum sensing. Here, we implement sequential measurements of modular variables in the oscillatory motion of a single trapped ion, using state-dependent displacements and a heralded nondestructive readout. We investigate the commutative nature of modular variable observables by demonstrating no-signaling in time between successive measurements, using a variety of input states. Employing a different periodicity, we observe signaling in time. This also requires wave-packet overlap, resulting in quantum interference that we enhance using squeezed input states. The sequential measurements allow us to extract two-time correlators for modular variables, which we use to violate a Leggett-Garg inequality. Signaling in time and Leggett-Garg inequalities serve as efficient quantum witnesses, which we probe here with a mechanical oscillator, a system that has a natural crossover from the quantum to the classical regime.

  7. 8. Photocopy of supplement to the Durango Herald, 1888. PORTION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photocopy of supplement to the Durango Herald, 1888. PORTION OF DRAWING SHOWING DISTANT VIEW OF SAN JUAN SMELTING AND MINING COMPANY WORKS IN FOREGROUND, WITH EXTANT SMELTER STACK AT RIGHT AND CITY OF DURANGO IN BACKGROUND, LOOKING WEST. (Original in possession of Durango Public Library. Artist unknown.) - San Juan & New York Mining & Smelting Company, Smelter Stack, State Route 160, Durango, La Plata County, CO

  8. Translations on Narcotics and Dangerous Drug No. 285

    DTIC Science & Technology

    1977-02-17

    AND DANGEROUS DRUGS No. 285 CONTENTS PAGE ASIA AUSTRALIA Attorney General Wants No Criminal Penalties for Marihuana Use (THE SYDNEY MORNING HERALD...13 Dec 76) 1 Pros and Cons of Marihuana Use Debated (THE SYDNEY MORNING HERALD, various dates) 3 BURMA Heroin Dealer Caught in Rangoon...Bail 57 Drug Move Planned 57 LATIN AMERICA COLOMBIA Briefs Cocaine Traffickers Arrest 58 Marihuana Plantation 58 Marihuana Haul 53 ECUADOR

  9. Microresonators for Nonlinear Quantum Optics

    NASA Astrophysics Data System (ADS)

    Vernon, Zachary

    In this thesis I study in detail the quantum dynamics of several nonlinear optical processes in microresonator systems. A Heisenberg-picture input-output formalism is developed from first principles that includes the effects of scattering losses and independent quality factors and coupling ratios for different resonances. The task of calculating the device output is then reduced to solving a set of driven, damped, ordinary differential equations for the resonator mode operators alone. This theoretical framework is used to study photon pair generation via spontaneous four-wave mixing in the weakly pumped regime, on which the effects of scattering losses are appraised. A more strongly driven regime is studied for continuous wave pumps, demonstrating when self- and cross-phase modulation and multi-photon pair generation become important, and their effects on the spectral and power scaling properties of the system are examined; A detuning strategy is presented that compensates for some of these effects. The results of the weak-pump regime are applied to study microresonator-based heralded single photon sources. The impact of scattering losses is studied, revealing that typical systems suffer from low heralding efficiency due to these losses. A technique to improve heralding efficiency is presented through over-coupling the resonator-channel system, and a resultant trade-off between heralding rate and heralding efficiency is uncovered. Limitations to the spectral purity of the heralded single photon output for conventional microresonator systems are also analysed, and a more sophisticated coupling scheme presented to overcome the upper bound for spectral purity of 93% that exists in typical systems, permitting the generation of single photons with spectral purity arbitrarily close to 100% without spectral filtering or sophisticated phase-matching techniques. The theory of quantum frequency conversion in microresonators using four-wave mixing is then developed in detail, and the spectral conversion probability and conversion efficiency studied. Efficiencies exceeding 90% using less than 100 mW of pump power are predicted to be achievable with current technology. A dressed mode picture is developed to better understand the conversion dynamics. Rabi-like spectral splitting and temporal oscillations of the intraresonator mean photon number are predicted, exhibiting a novel regime of strongly coupled photonic modes.

  10. On-chip generation of heralded photon-number states

    NASA Astrophysics Data System (ADS)

    Vergyris, Panagiotis; Meany, Thomas; Lunghi, Tommaso; Sauder, Gregory; Downes, James; Steel, M. J.; Withford, Michael J.; Alibart, Olivier; Tanzilli, Sébastien

    2016-10-01

    Beyond the use of genuine monolithic integrated optical platforms, we report here a hybrid strategy enabling on-chip generation of configurable heralded two-photon states. More specifically, we combine two different fabrication techniques, i.e., non-linear waveguides on lithium niobate for efficient photon-pair generation and femtosecond-laser-direct-written waveguides on glass for photon manipulation. Through real-time device manipulation capabilities, a variety of path-coded heralded two-photon states can be produced, ranging from product to entangled states. Those states are engineered with high levels of purity, assessed by fidelities of 99.5 ± 8% and 95.0 ± 8%, respectively, obtained via quantum interferometric measurements. Our strategy therefore stands as a milestone for further exploiting entanglement-based protocols, relying on engineered quantum states, and enabled by scalable and compatible photonic circuits.

  11. On-chip generation of heralded photon-number states

    PubMed Central

    Vergyris, Panagiotis; Meany, Thomas; Lunghi, Tommaso; Sauder, Gregory; Downes, James; Steel, M. J.; Withford, Michael J.; Alibart, Olivier; Tanzilli, Sébastien

    2016-01-01

    Beyond the use of genuine monolithic integrated optical platforms, we report here a hybrid strategy enabling on-chip generation of configurable heralded two-photon states. More specifically, we combine two different fabrication techniques, i.e., non-linear waveguides on lithium niobate for efficient photon-pair generation and femtosecond-laser-direct-written waveguides on glass for photon manipulation. Through real-time device manipulation capabilities, a variety of path-coded heralded two-photon states can be produced, ranging from product to entangled states. Those states are engineered with high levels of purity, assessed by fidelities of 99.5 ± 8% and 95.0 ± 8%, respectively, obtained via quantum interferometric measurements. Our strategy therefore stands as a milestone for further exploiting entanglement-based protocols, relying on engineered quantum states, and enabled by scalable and compatible photonic circuits. PMID:27775062

  12. Surface code quantum communication.

    PubMed

    Fowler, Austin G; Wang, David S; Hill, Charles D; Ladd, Thaddeus D; Van Meter, Rodney; Hollenberg, Lloyd C L

    2010-05-07

    Quantum communication typically involves a linear chain of repeater stations, each capable of reliable local quantum computation and connected to their nearest neighbors by unreliable communication links. The communication rate of existing protocols is low as two-way classical communication is used. By using a surface code across the repeater chain and generating Bell pairs between neighboring stations with probability of heralded success greater than 0.65 and fidelity greater than 0.96, we show that two-way communication can be avoided and quantum information can be sent over arbitrary distances with arbitrarily low error at a rate limited only by the local gate speed. This is achieved by using the unreliable Bell pairs to measure nonlocal stabilizers and feeding heralded failure information into post-transmission error correction. Our scheme also applies when the probability of heralded success is arbitrarily low.

  13. Heralded noiseless amplification for single-photon entangled state with polarization feature

    NASA Astrophysics Data System (ADS)

    Wang, Dan-Dan; Jin, Yu-Yu; Qin, Sheng-Xian; Zu, Hao; Zhou, Lan; Zhong, Wei; Sheng, Yu-Bo

    2018-03-01

    Heralded noiseless amplification is a promising method to overcome the transmission photon loss in practical noisy quantum channel and can effectively lengthen the quantum communication distance. Single-photon entanglement is an important resource in current quantum communications. Here, we construct two single-photon-assisted heralded noiseless amplification protocols for the single-photon two-mode entangled state and single-photon three-mode W state, respectively, where the single-photon qubit has an arbitrary unknown polarization feature. After the amplification, the fidelity of the single-photon entangled state can be increased, while the polarization feature of the single-photon qubit can be well remained. Both the two protocols only require the linear optical elements, so that they can be realized under current experimental condition. Our protocols may be useful in current and future quantum information processing.

  14. The Sleep of the Saved and Thankful

    DTIC Science & Technology

    2009-03-16

    the media working with the BSC, including Henry Luce, publisher of Time, Life and Fortune magazines; Walter Lippmann, columnist for the Herald Tribune...Walter Winchell, whose syndicated gossip column was read by over 50 million people in more than 2,000 papers worldwide; Arthur H. Sulzberger...York Herald Tribune, the New York Post, and the Baltimore Sun, – the places where the BSC had the most success in finding sympathetic columnists and

  15. JPRS Report, East Asia, Southeast Asia.

    DTIC Science & Technology

    1988-09-22

    Individual Initiative 7 NEW ZEALAND Lange Terms Fiji Pacific’s First Police State [Sydney THE SYDNEY MORNING HERALD 25 Jun] 8 THAILAND Editorial...Lange Terms Fiji Pacific’s First Police State 42000434 Sydney THE SYDNEY MORNING HERALD in English 25 Jun 88 p 17 [By David Barber] [Text] Wellington...tourists not to go to Fiji and said New Zealand lawyers engaged to defend those arrested there faced detention and deportation. The powers of the

  16. Military Herald Indices (1975-1979). Volume 2

    DTIC Science & Technology

    1988-11-01

    KALININ,V.COL., S "YEDIN.S.ENGR.LC.CTS. 1977 APR TRAINER EXERCISE.: KISELEV.P.. SHILOV.A. 1976 FEB TRAINER FOR FIRING TRAINING; A CLASSROOM .: YAROSHEVSKIY,V...Military Herald Indices (1975-1979) 0 C\\I Volume I! Allan S . Rehm Lauren Van Metre Charles B. Hall DTIC ELECTE JUN 02 1989 A Division of Hudson...AVAILABILITY OF REPORT . DECLASSIFIATIN /Approved for Public Release; Distribution unlimited 4. PERFORM NG ORGANIZATION REPORT NUMBER( S ) S . MONITORING

  17. Heralded quantum repeater based on the scattering of photons off single emitters using parametric down-conversion source.

    PubMed

    Song, Guo-Zhu; Wu, Fang-Zhou; Zhang, Mei; Yang, Guo-Jian

    2016-06-28

    Quantum repeater is the key element in quantum communication and quantum information processing. Here, we investigate the possibility of achieving a heralded quantum repeater based on the scattering of photons off single emitters in one-dimensional waveguides. We design the compact quantum circuits for nonlocal entanglement generation, entanglement swapping, and entanglement purification, and discuss the feasibility of our protocols with current experimental technology. In our scheme, we use a parametric down-conversion source instead of ideal single-photon sources to realize the heralded quantum repeater. Moreover, our protocols can turn faulty events into the detection of photon polarization, and the fidelity can reach 100% in principle. Our scheme is attractive and scalable, since it can be realized with artificial solid-state quantum systems. With developed experimental technique on controlling emitter-waveguide systems, the repeater may be very useful in long-distance quantum communication.

  18. Surpassing the no-cloning limit with a heralded hybrid linear amplifier for coherent states

    PubMed Central

    Haw, Jing Yan; Zhao, Jie; Dias, Josephine; Assad, Syed M.; Bradshaw, Mark; Blandino, Rémi; Symul, Thomas; Ralph, Timothy C.; Lam, Ping Koy

    2016-01-01

    The no-cloning theorem states that an unknown quantum state cannot be cloned exactly and deterministically due to the linearity of quantum mechanics. Associated with this theorem is the quantitative no-cloning limit that sets an upper bound to the quality of the generated clones. However, this limit can be circumvented by abandoning determinism and using probabilistic methods. Here, we report an experimental demonstration of probabilistic cloning of arbitrary coherent states that clearly surpasses the no-cloning limit. Our scheme is based on a hybrid linear amplifier that combines an ideal deterministic linear amplifier with a heralded measurement-based noiseless amplifier. We demonstrate the production of up to five clones with the fidelity of each clone clearly exceeding the corresponding no-cloning limit. Moreover, since successful cloning events are heralded, our scheme has the potential to be adopted in quantum repeater, teleportation and computing applications. PMID:27782135

  19. Heralded quantum repeater based on the scattering of photons off single emitters using parametric down-conversion source

    PubMed Central

    Song, Guo-Zhu; Wu, Fang-Zhou; Zhang, Mei; Yang, Guo-Jian

    2016-01-01

    Quantum repeater is the key element in quantum communication and quantum information processing. Here, we investigate the possibility of achieving a heralded quantum repeater based on the scattering of photons off single emitters in one-dimensional waveguides. We design the compact quantum circuits for nonlocal entanglement generation, entanglement swapping, and entanglement purification, and discuss the feasibility of our protocols with current experimental technology. In our scheme, we use a parametric down-conversion source instead of ideal single-photon sources to realize the heralded quantum repeater. Moreover, our protocols can turn faulty events into the detection of photon polarization, and the fidelity can reach 100% in principle. Our scheme is attractive and scalable, since it can be realized with artificial solid-state quantum systems. With developed experimental technique on controlling emitter-waveguide systems, the repeater may be very useful in long-distance quantum communication. PMID:27350159

  20. Hybrid microfiber-lithium-niobate nanowaveguide structures as high-purity heralded single-photon sources

    NASA Astrophysics Data System (ADS)

    Main, Philip; Mosley, Peter J.; Ding, Wei; Zhang, Lijian; Gorbach, Andrey V.

    2016-12-01

    We propose a compact, fiber-integrated architecture for photon-pair generation by parametric downconversion with unprecedented flexibility in the properties of the photons produced. Our approach is based on a thin-film lithium niobate nanowaveguide, evanescently coupled to a tapered silica microfiber. We demonstrate how controllable mode hybridization between the fiber and waveguide yields control over the joint spectrum of the photon pairs. We also investigate how independent engineering of the linear and nonlinear properties of the structure can be achieved through the addition of a tapered, proton-exchanged layer to the waveguide. This allows further refinement of the joint spectrum through custom profiling of the effective nonlinearity, drastically improving the purity of the heralded photons. We give details of a source design capable of generating heralded single photons in the telecom wavelength range with purity of at least 0.95, and we provide a feasible fabrication methodology.

  1. Air quality and electricity: What competition may mean

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burtraw, D.; Krupnick, A.J.; Palmer, K.L.

    1996-12-31

    Although the likely breakup of the US electricity industry is heralded as an economic boon to business and consumers alike, the downside to more competition is debatable, especially since the uncertainties involved are many. Whether the air we breathe improves or worsens will depend on choices consumers, producers, and policymakers have yet to make. Economic analysis of alternative regulatory options offers insights into what could happen.

  2. Arctic pathways of Pacific Water: Arctic Ocean Model Intercomparison experiments

    PubMed Central

    Karcher, Michael; Proshutinsky, Andrey; Gerdes, Rüdiger; de Cuevas, Beverly; Golubeva, Elena; Kauker, Frank; Nguyen, An T.; Platov, Gennady A.; Wadley, Martin; Watanabe, Eiji; Coward, Andrew C.; Nurser, A. J. George

    2016-01-01

    Abstract Pacific Water (PW) enters the Arctic Ocean through Bering Strait and brings in heat, fresh water, and nutrients from the northern Bering Sea. The circulation of PW in the central Arctic Ocean is only partially understood due to the lack of observations. In this paper, pathways of PW are investigated using simulations with six state‐of‐the art regional and global Ocean General Circulation Models (OGCMs). In the simulations, PW is tracked by a passive tracer, released in Bering Strait. Simulated PW spreads from the Bering Strait region in three major branches. One of them starts in the Barrow Canyon, bringing PW along the continental slope of Alaska into the Canadian Straits and then into Baffin Bay. The second begins in the vicinity of the Herald Canyon and transports PW along the continental slope of the East Siberian Sea into the Transpolar Drift, and then through Fram Strait and the Greenland Sea. The third branch begins near the Herald Shoal and the central Chukchi shelf and brings PW into the Beaufort Gyre. In the models, the wind, acting via Ekman pumping, drives the seasonal and interannual variability of PW in the Canadian Basin of the Arctic Ocean. The wind affects the simulated PW pathways by changing the vertical shear of the relative vorticity of the ocean flow in the Canada Basin. PMID:27818853

  3. Translations on Narcotics and Dangerous Drugs, Number 292.

    DTIC Science & Technology

    1977-03-30

    Reports Figures on Marihuana (THE AGE, 28 Feb 77) 1 High Court Rules on Loopholes in Drug Laws (THE AGE, 26 Feh 77) 3 Heroin Addicts Will Be...Given the Choice of Voluntary Treatment (THE WEST AUSTRALIAN, 19 Feb 77) 5 Wo Intention of Legalising Marihuana (THE SYDNEY MORNING HERALD, 2...Rehabilitation Center (THE SYDNEY MORNING HERALD, 10 Mar 77) 11 Drug Therapy Instead of Jail (THE AUSTRALIAN, 2 Mar 77) 15 2 Tons of Marihuana

  4. Heralded entanglement of two ions in an optical cavity.

    PubMed

    Casabone, B; Stute, A; Friebe, K; Brandstätter, B; Schüppert, K; Blatt, R; Northup, T E

    2013-09-06

    We demonstrate precise control of the coupling of each of two trapped ions to the mode of an optical resonator. When both ions are coupled with near-maximum strength, we generate ion-ion entanglement heralded by the detection of two orthogonally polarized cavity photons. The entanglement fidelity with respect to the Bell state Ψ+ reaches F≥(91.9±2.5)%. This result represents an important step toward distributed quantum computing with cavities linking remote atom-based registers.

  5. Creating Cover and Constructing Capacity: Assessing the Origins, Evolution, and Impact of Race to the Top. Education Stimulus Watch. Special Report 6

    ERIC Educational Resources Information Center

    McGuinn, Patrick

    2010-01-01

    The Obama administration's Race to the Top (RTT) competitive grant program has been heralded for revolutionizing the federal role in education and transforming state school reform efforts. This paper offers an initial analysis of the origins, evolution, and impact of RTT. In many ways, RTT is an attempt to circumvent the perceived failings of No…

  6. Heralded ions via ionization coincidence

    NASA Astrophysics Data System (ADS)

    McCulloch, A. J.; Speirs, R. W.; Wissenberg, S. H.; Tielen, R. P. M.; Sparkes, B. M.; Scholten, R. E.

    2018-04-01

    We demonstrate a method for the deterministic production of single ions by exploiting the correlation between an electron and associated ion following ionization. Coincident detection and feedback in combination with Coulomb-driven particle selection allows for high-fidelity heralding of ions at a high repetition rate. Extension of the scheme beyond time-correlated feedback to position- and momentum-correlated feedback will provide a general and powerful means to optimize the ion beam brightness for the development of next-generation focused ion beam technologies.

  7. Realization of a Cascaded Quantum System: Heralded Absorption of a Single Photon Qubit by a Single-Electron Charged Quantum Dot.

    PubMed

    Delteil, Aymeric; Sun, Zhe; Fält, Stefan; Imamoğlu, Atac

    2017-04-28

    Photonic losses pose a major limitation for the implementation of a quantum state transfer between nodes of a quantum network. A measurement that heralds a successful transfer without revealing any information about the qubit may alleviate this limitation. Here, we demonstrate the heralded absorption of a single photonic qubit, generated by a single neutral quantum dot, by a single-electron charged quantum dot that is located 5 m away. The transfer of quantum information to the spin degree of freedom takes place upon the emission of a photon; for a properly chosen or prepared quantum dot, the detection of this photon yields no information about the qubit. We show that this process can be combined with local operations optically performed on the destination node by measuring classical correlations between the absorbed photon color and the final state of the electron spin. Our work suggests alternative avenues for the realization of quantum information protocols based on cascaded quantum systems.

  8. Experimental protocol for high-fidelity heralded photon-to-atom quantum state transfer.

    PubMed

    Kurz, Christoph; Schug, Michael; Eich, Pascal; Huwer, Jan; Müller, Philipp; Eschner, Jürgen

    2014-11-21

    A quantum network combines the benefits of quantum systems regarding secure information transmission and calculational speed-up by employing quantum coherence and entanglement to store, transmit and process information. A promising platform for implementing such a network are atom-based quantum memories and processors, interconnected by photonic quantum channels. A crucial building block in this scenario is the conversion of quantum states between single photons and single atoms through controlled emission and absorption. Here we present an experimental protocol for photon-to-atom quantum state conversion, whereby the polarization state of an absorbed photon is mapped onto the spin state of a single absorbing atom with >95% fidelity, while successful conversion is heralded by a single emitted photon. Heralded high-fidelity conversion without affecting the converted state is a main experimental challenge, in order to make the transferred information reliably available for further operations. We record >80 s(-1) successful state transfer events out of 18,000 s(-1) repetitions.

  9. Foundations of Quantum Mechanics: recent developments at INRIM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Genovese, Marco; Piacentini, Fabrizio

    2011-09-23

    This paper's purpose is to show some experiments performed in the 'Carlo Novero' labs of the Optics Division of the National Institute of Metrological Research (INRIM, Torino, Italy) in the last years, aiming to discriminate between Standard Quantum Mechanics and some specific, restricted class of Hidden Variable Theories (HVTs).The first experiment, realized in two different configurations, will perform the Alicki - Van Ryn non-classicality test on single particles, in our specific case heralded single photons. The second experiment instead will be on the testing of two restricted Local Realistic Theories (LRTs), properly built to describe polarization entangled photons experiments, whosemore » inequalities are not affected by the detection loophole.« less

  10. Storage and retrieval of THz-bandwidth single photons using a room-temperature diamond quantum memory.

    PubMed

    England, Duncan G; Fisher, Kent A G; MacLean, Jean-Philippe W; Bustard, Philip J; Lausten, Rune; Resch, Kevin J; Sussman, Benjamin J

    2015-02-06

    We report the storage and retrieval of single photons, via a quantum memory, in the optical phonons of a room-temperature bulk diamond. The THz-bandwidth heralded photons are generated by spontaneous parametric down-conversion and mapped to phonons via a Raman transition, stored for a variable delay, and released on demand. The second-order correlation of the memory output is g((2))(0)=0.65±0.07, demonstrating a preservation of nonclassical photon statistics throughout storage and retrieval. The memory is low noise, high speed and broadly tunable; it therefore promises to be a versatile light-matter interface for local quantum processing applications.

  11. School Internet Use, Youth and Risk: A Social-Cultural Study of the Relation between Staff Views of Online Dangers and Students' Ages in UK Schools

    ERIC Educational Resources Information Center

    Hope, Andrew

    2006-01-01

    Internet access has recently been introduced into over 30,000 schools in the UK. While web provision has been heralded by some as an educational panacea, it is also recognised that there are dangers inherent in school Internet use. Adopting the cultural risk perspective, drawing upon a social-cultural analysis of Internet regulation and utilising…

  12. Unilateral temporal myositis heralding polymyositis: ultrasonographic and elastographic findings. Case report.

    PubMed

    Damian, Laura; Botar Jid, Carolina; Rogojan, Liliana; Dinu, Cristian; Maniu, Alma; Fodor, Daniela; Rednic, Simona; Simon, Siao-Pin

    2016-03-01

    Temporal myositis is a rare inflammatory disease of the temporal muscle. We report a case of unilateral temporal myositis, in which a polymyositis was diagnosed two years thereafter. Although focal myositis may rarely herald polymyositis, isolated temporal myositis preceding inflammatory myopathies has not been described, to our knowledge. In the setting of a temporal pain and swelling, ultrasonography may help in diagnosis, biopsy guidance, disease extension, and progression assessment. Further studies are necessary to establish the role of elastography in differentiating between muscle inflammation and hypertrophy.

  13. Holocene Ostracoda from the Herald Canyon, Eastern Siberian Sea from the SWERUS-C3 Expedition 2014

    NASA Astrophysics Data System (ADS)

    Gemery, L.; Cronin, T. M.; Jakobsson, M.; Barrientos, N.; O'Regan, M.; Muschitiello, F.; Koshurnikov, A.; Gukov, A.

    2015-12-01

    We analyzed Arctic benthic ostracode assemblages from two piston cores (PC) and their complementary multicores from Herald Canyon in the Eastern Siberian Sea. The cores (SWERUS-L2-2-PC1 [8.1 m], 2-MUC4, 71.7 m water depth, and SWERUS-L2-4-PC1 [6.2 m], 4-MUC4, 119.7 m water depth) were collected during Leg 2 of the 2014 SWERUS-C3 Expedition. Radiocarbon dates on mollusks indicate that sediments from 2-PC1 and 4-PC1 were deposited over the last 5,000 and 10,000 years respectively. The dominant ostracode species include: Acanthocythereis dunelmensis, Cytheropteron elaeni, Elofsonella concinna, Kotoracythere janae, Normanicythere leioderma, Semicytherura complanata. Based on species' distributions obtained from a 1,200-sample modern ostracode database, these species are known to be typical of shallow mid- to outer-continental shelf environments in the modern Arctic Ocean. The abundant and diverse benthic ostracode assemblages found in these cores suggest the influence of nutrient-rich Pacific water flowing in through the Bering Strait. The faunal assemblages are fairly uniform throughout 2-PC1, suggesting minimal variability in Pacific water inflow since at least 5 ka. In the lower section of 4-PC1, there is a major change to ostracode assemblages containing typical inner shelf, often brackish-water species, such as Cytheromorpha macchesneyi, and associated shallow Arctic shelf species (Sarsicytheridea punctillata and several Cytheropteron species), reflecting a period of lower, deglacial sea level.

  14. Single photon source with individualized single photon certifications

    NASA Astrophysics Data System (ADS)

    Migdall, Alan L.; Branning, David A.; Castelletto, Stefania; Ware, M.

    2002-12-01

    As currently implemented, single-photon sources cannot be made to produce single photons with high probability, while simultaneously suppressing the probability of yielding two or more photons. Because of this, single photon sources cannot really produce single photons on demand. We describe a multiplexed system that allows the probabilities of producing one and more photons to be adjusted independently, enabling a much better approximation of a source of single photons on demand. The scheme uses a heralded photon source based on parametric downconversion, but by effectively breaking the trigger detector area into multiple regions, we are able to extract more information about a heralded photon than is possible with a conventional arrangement. This scheme allows photons to be produced along with a quantitative 'certification' that they are single photons. Some of the single-photon certifications can be significantly better than what is possible with conventional downconversion sources, as well as being better than faint laser sources. With such a source of more tightly certified single photons, it should be possible to improve the maximum secure bit rate possible over a quantum cryptographic link. We present an analysis of the relative merits of this method over the conventional arrangement.

  15. Detection of Apoptosis in Early Life Stages as a Tool to Evaluate Chemical Control of Invasive Species

    DTIC Science & Technology

    2007-08-01

    ERDC/TN ANSRP-07-2 August 2007 Detection of Apoptosis in Early Life Stages as a Tool to Evaluate Chemical Control of Invasive Species by J...4. TITLE AND SUBTITLE Detection of Apoptosis in Early Life Stages as a Tool to Evaluate Chemical Control of Invasive Species 5a. CONTRACT NUMBER 5b...heralding apoptosis . Data analysis. An apoptotic index (API) was established by calculating the percentage of embryos in each life stage with

  16. Disaster Response Contracting in a Post-Katrina World: Analyzing Current Disaster Response Strategies and Exploring Alternatives to Improve Processes for Rapid Reaction to Large Scale Disasters within the United States

    DTIC Science & Technology

    2006-12-01

    could benefit tremendously from pre-positioning within the Corps of Engineers ’ ID/IQ contracts or catalogs for the essential services and commodities...even advisable? 5. Telework, An In Depth Cost Benefit Analysis Proactively managed telecommuting programs have been heralded as a cost saving...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA MBA PROFESSIONAL REPORT Disaster Response Contracting in a Post-Katrina World

  17. Noninvasive Prenatal Screening for Genetic Diseases Using Massively Parallel Sequencing of Maternal Plasma DNA

    PubMed Central

    Chitty, Lyn S.; Lo, Y. M. Dennis

    2015-01-01

    The identification of cell-free fetal DNA (cffDNA) in maternal plasma in 1997 heralded the most significant change in obstetric care for decades, with the advent of safer screening and diagnosis based on analysis of maternal blood. Here, we describe how the technological advances offered by next-generation sequencing have allowed for the development of a highly sensitive screening test for aneuploidies as well as definitive prenatal molecular diagnosis for some monogenic disorders. PMID:26187875

  18. Upper Cretaceous and Lower Jurassic strata in shallow cores on the Chukchi Shelf, Arctic Alaska: Chapter C in Studies by the U.S. Geological Survey in Alaska, vol. 15

    USGS Publications Warehouse

    Houseknecht, David W.; Craddock, William H.; Lease, Richard O.

    2016-02-12

    Shallow cores collected in the 1980s on the Chukchi Shelf of western Arctic Alaska sampled pre-Cenozoic strata whose presence, age, and character are poorly known across the region. Five cores from the Herald Arch foreland contain Cenomanian to Coniacian strata, as documented by biostratigraphy, geochronology, and thermochronology. Shallow seismic reflection data collected during the 1970s and 1980s show that these Upper Cretaceous strata are truncated near the seafloor by subtle angular unconformities, including the Paleogene mid-Brookian unconformity in one core and the Pliocene-Pleistocene unconformity in four cores. Sedimentary structures and lithofacies suggest that Upper Cretaceous strata were deposited in a low accommodation setting that ranged from low-lying coastal plain (nonmarine) to muddy, shallow-marine environments near shore. These observations, together with sparse evidence from the adjacent western North Slope, suggest that Upper Cretaceous strata likely were deposited across all of Arctic Alaska.A sixth core from the Herald Arch contains lower Toarcian marine strata, indicated by biostratigraphy, truncated by a Neogene or younger unconformity. These Lower Jurassic strata evidently were deposited south of the arch, buried structurally to high levels of thermal maturity during the Early Cretaceous, and uplifted on the Herald thrust-fault system during the mid to Late Cretaceous. These interpretations are based on regional stratigraphy and apatite fission-track data reported in a complementary report and are corroborated by the presence of recycled palynomorphs of Early Jurassic age and high thermal maturity found in Upper Cretaceous strata in two of the foreland cores. This dataset provides evidence that uplift and exhumation of the Herald thrust belt provided sediment to the foreland during the Late Cretaceous.

  19. On the nature and origin of water masses in Herald Canyon, Chukchi Sea: Synoptic surveys in summer 2004, 2008, and 2009

    NASA Astrophysics Data System (ADS)

    Linders, Johanna; Pickart, Robert. S.; Björk, Göran; Moore, G. W. K.

    2017-12-01

    Hydrographic and velocity data from three high-resolution shipboard surveys of Herald Canyon in the northwest Chukchi Sea, in 2004, 2008, and 2009, are used to investigate the water masses in the canyon and their possible source regions. Both summer and winter Pacific waters were observed in varying amounts in the different years, although in general the summer waters resided on the eastern side of the canyon while the winter waters were located on the western flank. The predominant summer water was Bering summer water, although some Alaskan coastal water resided in the canyon in the two later years likely due to wind forcing. Both newly ventilated and remnant winter waters were found in the canyon, but the amount lessened in each successive survey. Using mooring data from Bering Strait it is shown that a large amount of Bering summer water in the western channel of the strait follows a relatively direct route into Herald Canyon during the summer months, with an estimated advective speed of 10-20 cm/s. However, while the winter water observed in 2004 was consistent with a Bering Strait source (with a slower advective speed of 5-8 cm/s), the dense water in the canyon during 2008 and 2009 was more in line with a northern source. This is consistent with sections to the west of the canyon and with previously reported measurements implying winter water formation on the East Siberian shelf. Large-scale wind patterns and polynya activity on the shelf are also investigated. It was found that the former appears to impact more strongly the presence of dense water in Herald Canyon.

  20. Single-photon superradiant beating from a Doppler-broadened ladder-type atomic ensemble

    NASA Astrophysics Data System (ADS)

    Lee, Yoon-Seok; Lee, Sang Min; Kim, Heonoh; Moon, Han Seb

    2017-12-01

    We report on heralded-single-photon superradiant beating in the spontaneous four-wave mixing process of Doppler-broadened ladder-type 87Rb atoms. When Doppler-broadened atoms contribute to two-photon coherence, the detection probability amplitudes of the heralded single photons are coherently superposed despite inhomogeneous broadened atomic media. Single-photon superradiant beating is observed, which constitutes evidence for the coherent superposition of two-photon amplitudes from different velocity classes in the Doppler-broadened atomic ensemble. We present a theoretical model in which the single-photon superradiant beating originates from the interference between wavelength-separated two-photon amplitudes via the reabsorption filtering effect.

  1. High heralding-efficiency of near-IR fiber coupled photon pairs for quantum technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dixon, P. Ben; Murphy, Ryan; Rosenberg, Danna

    We report on the development and use of a high heralding-efficiency, single-mode-fiber coupled telecom-band source of entangled photons for quantum technology applications. The source development efforts consisted of theoretical and experimental efforts and we demonstrated a correlated-mode coupling efficiency of 97% 2%, the highest efficiency yet achieved for this type of system. We then incorporated these beneficial source development techniques in a Sagnac configured telecom-band entangled photon source that generates photon pairs entangled in both time/energy and polarization degrees of freedom. We made use of these highly desirable entangled states to investigate several promising quantum technologies.

  2. Accelerating Next Generation Vaccine Development for Global Disease Prevention

    PubMed Central

    Koff, Wayne C; Burton, Dennis R.; R.Johnson, Philip; Walker, Bruce D.; King, Charles R.; Nabel, Gary J.; Ahmed, Rafi; Bhan, Maharaj Kishan; Plotkin, Stanley A.

    2014-01-01

    Summary Vaccines are among the greatest successes in the history of public health. However, past strategies for vaccine development are unlikely to succeed in the future against major global diseases such as AIDS, TB, and malaria. For such diseases, the correlates of protection are poorly defined and the pathogens evade immune detection and/or exhibit extensive genetic variability. Recent advances have heralded in a new era of vaccine discovery. However, translation of these advances into vaccines remains impeded by lack of understanding of key vaccinology principles in humans. We review these advances towards vaccine discovery and suggest that for accelerating successful vaccine development, new human immunology-based clinical research initiatives be implemented with the goal of elucidating and more effectively inducing vaccine-induced protective immune responses. PMID:23723240

  3. Mosaics of Change: Cross-Scale Forest Cover Dynamics and Drivers in Tibetan Yunnan, China

    NASA Astrophysics Data System (ADS)

    Van Den Hoek, Jamon

    In reaction to devastating floods on the Yangtze River in the summer of 1998, the Chinese Central Government introduced a logging ban as part of the Natural Forest Protection Program (NFPP) with the goal of dramatically increasing national forest cover. Since then, over 11 billion USD has been allocated to the program, but the NFPP's success at promoting reforestation is unclear as neither the extent of forest cover change, nor the potential factors influencing the spatial variability of change have been examined. This research employs a case study in northwest Yunnan Province, southwest China, to evaluate the spatial variability of forest cover change under the NFPP and investigate drivers that have influenced recent patterns of change. I employ a mixed methods, cross-scale research framework that includes the analysis of areal trajectories and spatial variability of Landsat-5 imagery-derived forest cover change at three administrative levels before and after the NFPP's introduction; landscape ecology-based metrics to measure the shifting patterns of forest cover change at the patch level; and household interview data on village-level forest resource use patterns and processes in three neighboring villages. Prefecture- and county-level analyses suggest rather stable forest cover across the three-county study area since the introduction of the ban, though township-level measures of forest cover change show a degree of spatial variability as well as a temporal delay in policy implementation effectiveness. Village-level remote sensing analysis shows comparable amounts of forest cover change between study villages but disparate forest resource use patterns in terms of location and amount. Though all research villages continue to exploit local forests for firewood and timber relatively unfettered by policy restrictions, villagers with tourism-derived income are able to buy forest products collected in outside forests much more often; this redistributes local-scale deforestation to the benefit of local and detriment of distant forests. Tourism is often heralded as the solution to rural development challenges in China's southwest, but this research shows the unintended consequences that may result from inconsistent participation at the village-level, consequences which merely redirect, not reduce, forest use pressures, and that are contrary to the goals of state policy.

  4. Integrated-optics heralded controlled-NOT gate for polarization-encoded qubits

    NASA Astrophysics Data System (ADS)

    Zeuner, Jonas; Sharma, Aditya N.; Tillmann, Max; Heilmann, René; Gräfe, Markus; Moqanaki, Amir; Szameit, Alexander; Walther, Philip

    2018-03-01

    Recent progress in integrated-optics technology has made photonics a promising platform for quantum networks and quantum computation protocols. Integrated optical circuits are characterized by small device footprints and unrivalled intrinsic interferometric stability. Here, we take advantage of femtosecond-laser-written waveguides' ability to process polarization-encoded qubits and present an implementation of a heralded controlled-NOT gate on chip. We evaluate the gate performance in the computational basis and a superposition basis, showing that the gate can create polarization entanglement between two photons. Transmission through the integrated device is optimized using thermally expanded core fibers and adiabatically reduced mode-field diameters at the waveguide facets. This demonstration underlines the feasibility of integrated quantum gates for all-optical quantum networks and quantum repeaters.

  5. Virtopsy: An integration of forensic science and imageology

    PubMed Central

    Joseph, T. Isaac; Girish, K. L.; Sathyan, Pradeesh; Kiran, M. Shashi; Vidya, S.

    2017-01-01

    In an era where noninvasive and minimally invasive techniques are heralding medical innovations and health science technology, necrological analysis is not bereft of this wave. Virtopsy is virtual autopsy. It is a new-age complimentary documentation approach to identify and analyze the details of demise. Utilizing virtual autopsy for orofacial forensic examination is an emerging specialty which holds a plethora of potential for future trends in forensic science. Being a noninvasive technique, it is a rapid method which facilitates the medicolegal process and aids in the delivery of justice. The present article is an overview of this emerging methodology. PMID:29657485

  6. Virtopsy: An integration of forensic science and imageology.

    PubMed

    Joseph, T Isaac; Girish, K L; Sathyan, Pradeesh; Kiran, M Shashi; Vidya, S

    2017-01-01

    In an era where noninvasive and minimally invasive techniques are heralding medical innovations and health science technology, necrological analysis is not bereft of this wave. Virtopsy is virtual autopsy. It is a new-age complimentary documentation approach to identify and analyze the details of demise. Utilizing virtual autopsy for orofacial forensic examination is an emerging specialty which holds a plethora of potential for future trends in forensic science. Being a noninvasive technique, it is a rapid method which facilitates the medicolegal process and aids in the delivery of justice. The present article is an overview of this emerging methodology.

  7. Interacting supernovae and supernova impostors. LSQ13zm: an outburst heralds the death of a massive star

    DOE PAGES

    Tartaglia, L.; Pastorello, A.; Sullivan, M.; ...

    2016-03-23

    Here we report photometric and spectroscopic observations of the optical transient LSQ13zm. Historical data reveal the presence of an eruptive episode (that we label as ‘2013a’) followed by a much brighter outburst (‘2013b’) three weeks later, that we argue to be the genuine supernova explosion. This sequence of events closely resemble those observed for SN 2010mc and (in 2012) SN 2009ip. Furthermore, the absolute magnitude reached by LSQ13zm during 2013a (MR = -14.87 ± 0.25 mag) is comparable with those of supernova impostors, while that of the 2013b event (M R = -18.46 ± 0.21 mag) is consistent with thosemore » of interacting supernovae. Our spectra reveal the presence of a dense and structured circumstellar medium, probably produced through numerous pre-supernova mass-loss events. In addition, we find evidence for high-velocity ejecta, with a fraction of gas expelled at more than 20 000 km s -1. The spectra of LSQ13zm show remarkable similarity with those of well-studied core-collapse supernovae. From the analysis of the available photometric and spectroscopic data, we conclude that we first observed the last event of an eruptive sequence from a massive star, likely a Luminous Blue Variable, which a short time later exploded as a core-collapse supernova. Our detailed analysis of archival images suggests that the host galaxy is a star-forming Blue Dwarf Compact Galaxy.« less

  8. Interacting supernovae and supernova impostors. LSQ13zm: an outburst heralds the death of a massive star

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tartaglia, L.; Pastorello, A.; Sullivan, M.

    Here we report photometric and spectroscopic observations of the optical transient LSQ13zm. Historical data reveal the presence of an eruptive episode (that we label as ‘2013a’) followed by a much brighter outburst (‘2013b’) three weeks later, that we argue to be the genuine supernova explosion. This sequence of events closely resemble those observed for SN 2010mc and (in 2012) SN 2009ip. Furthermore, the absolute magnitude reached by LSQ13zm during 2013a (MR = -14.87 ± 0.25 mag) is comparable with those of supernova impostors, while that of the 2013b event (M R = -18.46 ± 0.21 mag) is consistent with thosemore » of interacting supernovae. Our spectra reveal the presence of a dense and structured circumstellar medium, probably produced through numerous pre-supernova mass-loss events. In addition, we find evidence for high-velocity ejecta, with a fraction of gas expelled at more than 20 000 km s -1. The spectra of LSQ13zm show remarkable similarity with those of well-studied core-collapse supernovae. From the analysis of the available photometric and spectroscopic data, we conclude that we first observed the last event of an eruptive sequence from a massive star, likely a Luminous Blue Variable, which a short time later exploded as a core-collapse supernova. Our detailed analysis of archival images suggests that the host galaxy is a star-forming Blue Dwarf Compact Galaxy.« less

  9. Experimental Demonstration of Quantum Stationary Light Pulses in an Atomic Ensemble

    NASA Astrophysics Data System (ADS)

    Park, Kwang-Kyoon; Cho, Young-Wook; Chough, Young-Tak; Kim, Yoon-Ho

    2018-04-01

    We report an experimental demonstration of the nonclassical stationary light pulse (SLP) in a cold atomic ensemble. A single collective atomic excitation is created and heralded by detecting a Stokes photon in the spontaneous Raman scattering process. The heralded single atomic excitation is converted into a single stationary optical excitation or the single-photon SLP, whose effective group velocity is zero, effectively forming a trapped single-photon pulse within the cold atomic ensemble. The single-photon SLP is then released from the atomic ensemble as an anti-Stokes photon after a specified trapping time. The second-order correlation measurement between the Stokes and anti-Stokes photons reveals the nonclassical nature of the single-photon SLP. Our work paves the way toward quantum nonlinear optics without a cavity.

  10. Entanglement distillation between solid-state quantum network nodes.

    PubMed

    Kalb, N; Reiserer, A A; Humphreys, P C; Bakermans, J J W; Kamerling, S J; Nickerson, N H; Benjamin, S C; Twitchen, D J; Markham, M; Hanson, R

    2017-06-02

    The impact of future quantum networks hinges on high-quality quantum entanglement shared between network nodes. Unavoidable imperfections necessitate a means to improve remote entanglement by local quantum operations. We realize entanglement distillation on a quantum network primitive of distant electron-nuclear two-qubit nodes. The heralded generation of two copies of a remote entangled state is demonstrated through single-photon-mediated entangling of the electrons and robust storage in the nuclear spins. After applying local two-qubit gates, single-shot measurements herald the distillation of an entangled state with increased fidelity that is available for further use. The key combination of generating, storing, and processing entangled states should enable the exploration of multiparticle entanglement on an extended quantum network. Copyright © 2017, American Association for the Advancement of Science.

  11. A happy "thumbs up" from the crew of the Space Shuttle Endeavour and NASA Dryden Flight Research Center officials heralded the successful completion of mission STS-100

    NASA Image and Video Library

    2001-05-01

    A happy "thumbs up" from the crew of the Space Shuttle Endeavour and NASA Dryden Flight Research Center officials heralded the successful completion of mission STS-100. Standing by the shuttle's rocket nozzles from left to right: Scott E. Prazynski, mission specialist (U.S.); Yuri V. Lonchakov, mission specialist (Russia); Kent V. Rominger, commander (U.S.); Wally Sawyer, NASA Dryden Flight Research Center deputy director; Kevin Petersen, NASA Dryden Flight Research Center director; Umberto Guidoni, mission specialist (European Space Agency); John L. Phillips, mission specialist (U.S.); Jeffrey S. Ashby, pilot (U.S.); and Chris A. Hadfield, mission specialist (Canadian Space Agency). The mission landed at Edwards Air Force Base, California, on May 1, 2001.

  12. Biased three-intensity decoy-state scheme on the measurement-device-independent quantum key distribution using heralded single-photon sources.

    PubMed

    Zhang, Chun-Hui; Zhang, Chun-Mei; Guo, Guang-Can; Wang, Qin

    2018-02-19

    At present, most of the measurement-device-independent quantum key distributions (MDI-QKD) are based on weak coherent sources and limited in the transmission distance under realistic experimental conditions, e.g., considering the finite-size-key effects. Hence in this paper, we propose a new biased decoy-state scheme using heralded single-photon sources for the three-intensity MDI-QKD, where we prepare the decoy pulses only in X basis and adopt both the collective constraints and joint parameter estimation techniques. Compared with former schemes with WCS or HSPS, after implementing full parameter optimizations, our scheme gives distinct reduced quantum bit error rate in the X basis and thus show excellent performance, especially when the data size is relatively small.

  13. Heralded amplification of path entangled quantum states

    NASA Astrophysics Data System (ADS)

    Monteiro, F.; Verbanis, E.; Caprara Vivoli, V.; Martin, A.; Gisin, N.; Zbinden, H.; Thew, R. T.

    2017-06-01

    Device-independent quantum key distribution (DI-QKD) represents one of the most fascinating challenges in quantum communication, exploiting concepts of fundamental physics, namely Bell tests of nonlocality, to ensure the security of a communication link. This requires the loophole-free violation of a Bell inequality, which is intrinsically difficult due to losses in fibre optic transmission channels. Heralded photon amplification (HPA) is a teleportation-based protocol that has been proposed as a means to overcome transmission loss for DI-QKD. Here we demonstrate HPA for path entangled states and characterise the entanglement before and after loss by exploiting a recently developed displacement-based detection scheme. We demonstrate that by exploiting HPA we are able to reliably maintain high fidelity entangled states over loss-equivalent distances of more than 50 km.

  14. Event-Ready Bell Test Using Entangled Atoms Simultaneously Closing Detection and Locality Loopholes

    NASA Astrophysics Data System (ADS)

    Rosenfeld, Wenjamin; Burchardt, Daniel; Garthoff, Robert; Redeker, Kai; Ortegel, Norbert; Rau, Markus; Weinfurter, Harald

    2017-07-01

    An experimental test of Bell's inequality allows ruling out any local-realistic description of nature by measuring correlations between distant systems. While such tests are conceptually simple, there are strict requirements concerning the detection efficiency of the involved measurements, as well as the enforcement of spacelike separation between the measurement events. Only very recently could both loopholes be closed simultaneously. Here we present a statistically significant, event-ready Bell test based on combining heralded entanglement of atoms separated by 398 m with fast and efficient measurements of the atomic spin states closing essential loopholes. We obtain a violation with S =2.221 ±0.033 (compared to the maximal value of 2 achievable with models based on local hidden variables) which allows us to refute the hypothesis of local realism with a significance level P <2.57 ×10-9.

  15. On-chip photonic synapse.

    PubMed

    Cheng, Zengguang; Ríos, Carlos; Pernice, Wolfram H P; Wright, C David; Bhaskaran, Harish

    2017-09-01

    The search for new "neuromorphic computing" architectures that mimic the brain's approach to simultaneous processing and storage of information is intense. Because, in real brains, neuronal synapses outnumber neurons by many orders of magnitude, the realization of hardware devices mimicking the functionality of a synapse is a first and essential step in such a search. We report the development of such a hardware synapse, implemented entirely in the optical domain via a photonic integrated-circuit approach. Using purely optical means brings the benefits of ultrafast operation speed, virtually unlimited bandwidth, and no electrical interconnect power losses. Our synapse uses phase-change materials combined with integrated silicon nitride waveguides. Crucially, we can randomly set the synaptic weight simply by varying the number of optical pulses sent down the waveguide, delivering an incredibly simple yet powerful approach that heralds systems with a continuously variable synaptic plasticity resembling the true analog nature of biological synapses.

  16. On-chip photonic synapse

    PubMed Central

    Cheng, Zengguang; Ríos, Carlos; Pernice, Wolfram H. P.; Wright, C. David; Bhaskaran, Harish

    2017-01-01

    The search for new “neuromorphic computing” architectures that mimic the brain’s approach to simultaneous processing and storage of information is intense. Because, in real brains, neuronal synapses outnumber neurons by many orders of magnitude, the realization of hardware devices mimicking the functionality of a synapse is a first and essential step in such a search. We report the development of such a hardware synapse, implemented entirely in the optical domain via a photonic integrated-circuit approach. Using purely optical means brings the benefits of ultrafast operation speed, virtually unlimited bandwidth, and no electrical interconnect power losses. Our synapse uses phase-change materials combined with integrated silicon nitride waveguides. Crucially, we can randomly set the synaptic weight simply by varying the number of optical pulses sent down the waveguide, delivering an incredibly simple yet powerful approach that heralds systems with a continuously variable synaptic plasticity resembling the true analog nature of biological synapses. PMID:28959725

  17. 32 CFR 507.6 - Authority to manufacture.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... companies who have manufacturing capability and agree to manufacture heraldic items according to applicable... to the Army and Air Force Exchange Service and, upon request, to Army and Air Force commanders. ...

  18. 32 CFR 507.6 - Authority to manufacture.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... companies who have manufacturing capability and agree to manufacture heraldic items according to applicable... to the Army and Air Force Exchange Service and, upon request, to Army and Air Force commanders. ...

  19. Translational bioinformatics in the cloud: an affordable alternative

    PubMed Central

    2010-01-01

    With the continued exponential expansion of publicly available genomic data and access to low-cost, high-throughput molecular technologies for profiling patient populations, computational technologies and informatics are becoming vital considerations in genomic medicine. Although cloud computing technology is being heralded as a key enabling technology for the future of genomic research, available case studies are limited to applications in the domain of high-throughput sequence data analysis. The goal of this study was to evaluate the computational and economic characteristics of cloud computing in performing a large-scale data integration and analysis representative of research problems in genomic medicine. We find that the cloud-based analysis compares favorably in both performance and cost in comparison to a local computational cluster, suggesting that cloud computing technologies might be a viable resource for facilitating large-scale translational research in genomic medicine. PMID:20691073

  20. Petermann Glacier, North Greenland: Large Ice-Discharge Episodes from 20 Years of Satellite Observations

    NASA Astrophysics Data System (ADS)

    Babiker, M.; Johannessen, O. M.; Miles, M. W.; Miles, V. V.

    2009-12-01

    The major marine-terminating outlet glaciers of Greenland can undergo large mass losses through calving of icebergs and bottom melting from floating ice tongues. Recent observations of outlet glaiers around Greenland have shown that large and rapid changes in solid-ice fluxes are possible. The Petermann glacier in remote northern Greenland is the region’s largest floating-tongue glacier (~70 km by 10 km). In summer 2008 a large calving event was observed, as well as large cracks upstream of the remaining calving front, portending a more massive near-term loss. These observations may herald extraordinary and unprecedented change. However, the long-term variability of calving events and ice velocities are poorly known. Our research goal here is to identify the temporal variability and possible trends in solid-ice flux indicators - variability of the calving front and ice velocity - for Petermann glacier. The methodological approach is observational, based primarily on analysis of 20 years of repetitive satellite data over a period starting from 1990, together with sporadic earlier observations. The multisensor data range from high-resolution optical images from Landsat, SPOT and Terra ASTER and high-resolution synthetic aperture radar (SAR) images from ERS and ENVISAT. These disparate data have been imported, geo-registered and analysed within a Geographic Information System. The following measurements are made: (1) delineating changes in the calving front, (2) estimating the area of glacial ice loss during calving events, and (3) estimating the ice-surface velocity using sequential satellite images. We find evidence of a number of previous calving episodes of similar magnitude to the summer 2008. The ice-velocity estimates compare well with other estimates for particular years, and moreover are relatively consistent during the 20-year period. These findings suggest business-as-usual for Petermann glacier; however, a near-term calving event exceeding those observed over the past 20 years cannot be ruled out.

  1. Imaging Alzheimer Pathology in Late-Life Depression With PET and Pittsburgh Compound-B

    PubMed Central

    Butters, Meryl A.; Klunk, William E.; Mathis, Chester A.; Price, Julie C.; Ziolko, Scott K.; Hoge, Jessica A.; Tsopelas, Nicholas D.; Lopresti, Brian J.; Reynolds, Charles F.; DeKosky, Steven T.; Meltzer, Carolyn C.

    2009-01-01

    There is increasing evidence for an empiric link between late-life depression and Alzheimer disease (AD). The neuropathology of AD, previously only confirmed at autopsy, may now be detectable in vivo using selective imaging ligands for β-amyloid. Positron emission tomography (PET) with [11C] 6-OH-BTA-1 [Pittsburgh Compound-B (PiB)] has shown high tracer retention in cortical areas in patients with clinical diagnoses of probable AD and low retention in age-matched controls. We also previously reported variable PiB retention in patients with mild cognitive impairment (MCI). In this study, we used PiB-PET to evaluate whether amyloid is present in elders with treated major depression, many of whom have persistent cognitive impairment. We evaluated 9 subjects with remitted major depression [3M: 6F, mean (SD) age=71.8(5.7) y]. Seven of the 9 depressed subjects also met criteria for the diagnosis of MCI. PiB-PET data from healthy elders [n=8; mean (SD) age=71.5(3.0) y] were used for comparison. PET was acquired with arterial sampling and PiB retention was quantified using magnetic resonance imaging-guided cortical regions and graphical analysis of time-activity data; arterial line failure led to exclusion of 1 depressed subject. The data demonstrated variably elevated PiB retention. PiB retention in the 2 depressed subjects with normal cognitive ability was in the range of nondepressed cognitively normal subjects. PiB retention in 3 of the 6 depressed subjects with MCI fell in the range of subjects with AD. PiB retention in the remaining 3 depressed subjects with cooccurring MCI was variable and generally was intermediate to the other subjects. Our findings are consistent with and supportive of the hypothesis that depression may herald the development of AD in some individuals. PMID:18580591

  2. 6 Common Cancers - Skin Cancer

    MedlinePlus

    ... Bar Home Current Issue Past Issues 6 Common Cancers - Skin Cancer Past Issues / Spring 2007 Table of Contents For ... AP Photo/Herald-Mail, Kevin G. Gilbert Skin Cancer Skin cancer is the most common form of ...

  3. Heralded quantum steering over a high-loss channel

    PubMed Central

    Weston, Morgan M.; Slussarenko, Sergei; Chrzanowski, Helen M.; Wollmann, Sabine; Shalm, Lynden K.; Verma, Varun B.; Allman, Michael S.; Nam, Sae Woo; Pryde, Geoff J.

    2018-01-01

    Entanglement is the key resource for many long-range quantum information tasks, including secure communication and fundamental tests of quantum physics. These tasks require robust verification of shared entanglement, but performing it over long distances is presently technologically intractable because the loss through an optical fiber or free-space channel opens up a detection loophole. We design and experimentally demonstrate a scheme that verifies entanglement in the presence of at least 14.8 ± 0.1 dB of added loss, equivalent to approximately 80 km of telecommunication fiber. Our protocol relies on entanglement swapping to herald the presence of a photon after the lossy channel, enabling event-ready implementation of quantum steering. This result overcomes the key barrier in device-independent communication under realistic high-loss scenarios and in the realization of a quantum repeater. PMID:29322093

  4. Heralded quantum steering over a high-loss channel.

    PubMed

    Weston, Morgan M; Slussarenko, Sergei; Chrzanowski, Helen M; Wollmann, Sabine; Shalm, Lynden K; Verma, Varun B; Allman, Michael S; Nam, Sae Woo; Pryde, Geoff J

    2018-01-01

    Entanglement is the key resource for many long-range quantum information tasks, including secure communication and fundamental tests of quantum physics. These tasks require robust verification of shared entanglement, but performing it over long distances is presently technologically intractable because the loss through an optical fiber or free-space channel opens up a detection loophole. We design and experimentally demonstrate a scheme that verifies entanglement in the presence of at least 14.8 ± 0.1 dB of added loss, equivalent to approximately 80 km of telecommunication fiber. Our protocol relies on entanglement swapping to herald the presence of a photon after the lossy channel, enabling event-ready implementation of quantum steering. This result overcomes the key barrier in device-independent communication under realistic high-loss scenarios and in the realization of a quantum repeater.

  5. Teenage Turning Point. Does Adolescence Herald the Twilight of Girls' Self-Esteem?

    ERIC Educational Resources Information Center

    Bower, Bruce

    1991-01-01

    Discussed is research related to the self-esteem of adolescents in the United States. Studies conducted by the American Association of University Women (AAUW), Carol Gilligan, and others are highlighted. (CW)

  6. Single Cell Analysis: From Technology to Biology and Medicine.

    PubMed

    Pan, Xinghua

    2014-01-01

    Single-cell analysis heralds a new era that allows "omics" analysis, notably genomics, transcriptomics, epigenomics and proteomics at the single-cell level. It enables the identification of the minor subpopulations that may play a critical role in a biological process of a population of cells, which conventionally are regarded as homogeneous. It provides an ultra-sensitive tool to clarify specific molecular mechanisms and pathways and reveal the nature of cell heterogeneity. It also facilitates the clinical investigation of patients when a very low quantity or a single cell is available for analysis, such as noninvasive prenatal diagnosis and cancer screening, and genetic evaluation for in vitro fertilization. Within a few short years, single-cell analysis, especially whole genomic sequencing and transcriptomic sequencing, is becoming robust and broadly accessible, although not yet a routine practice. Here, with single cell RNA-seq emphasized, an overview of the discipline, progresses, and prospects of single-cell analysis and its applications in biology and medicine are given with a series of logic and theoretical considerations.

  7. Hyperinsulinemia and hyperfiltration in renal transplantation.

    PubMed

    Porrini, Esteban; Bayes, Beatriz; Diaz, Juan M; Ibernon, Meritxell; Benitez, Rocio; Domínguez, Rosa; Moreno, Juan Manuel; Delgado, Patricia; Lauzurica, Ricardo; Silva, Irene; Moreso, Francisco; Lampreabe, Ildefonso; Arias, Manuel; Osuna, Antonio; Torres, Armando

    2009-01-27

    Insulin-resistance hyperinsulinemia is a novel risk factor for renal disease in the general population. Glomerular hyperfiltration has been proposed as an early consequence of hyperinsulinemia. In this multicenter cohort study, we analyzed 202 patients without diabetes before or after renal transplantation during the first posttransplant year. Insulin was measured at 3 and 12 months. The majority of patients (91%) were on calcineurin inhibitors. Patients were classified as with persistent normo or hyperinsulinemia when situated below or above the median value of insulin (3 months: 9 muU/mL; 12 months: 8.74 muU/mL) at both periods. The 3 to 12 months percent change in calculated creatinine clearance (3-12 months DeltaCrCL) was calculated. Patients with persistent hyperinsulinemia showed a higher increase in 3 to 12 months DeltaCrCL compared with those with persistent normoinsulinemia (12% [-20/40] vs. -0.03% [-12/18], P=0.035). We performed a multivariate linear regression analysis with the 3 to 12 months DeltaCrCL as the dependent variable and different factors that may induce hyperfiltration, including persistent hyperinsulinemia, as covariates. Persistent hyperinsulinemia was a risk factor for increased CrCL (beta 0.09, 95% CI 0.07/0.12, P=0.035). In nondiabetic recipients during the first posttransplant year, hyperinsulinemia induced increments in CrCL. As this may herald future renal dysfunction, hyperinsulinemia should not be ignored as a potential target in this population.

  8. The reawakening of Alaska's Augustine volcano

    USGS Publications Warehouse

    Power, John A.; Nye, Christopher J.; Coombs, Michelle L.; Wessels, Rick L.; Cervelli, Peter F.; Dehn, Jon; Wallace, Kristi L.; Freymueller, Jeffrey T.; Doukas, Michael P.

    2006-01-01

    The eruption was heralded by eight months of increasing seismicity, deformation, gas emission, and small phreatic eruptions, the latter consisting of explosions of steam and debris caused by heating and expansion of groundwater due to an underlying heat source.

  9. Engineering integrated photonics for heralded quantum gates

    NASA Astrophysics Data System (ADS)

    Meany, Thomas; Biggerstaff, Devon N.; Broome, Matthew A.; Fedrizzi, Alessandro; Delanty, Michael; Steel, M. J.; Gilchrist, Alexei; Marshall, Graham D.; White, Andrew G.; Withford, Michael J.

    2016-06-01

    Scaling up linear-optics quantum computing will require multi-photon gates which are compact, phase-stable, exhibit excellent quantum interference, and have success heralded by the detection of ancillary photons. We investigate the design, fabrication and characterisation of the optimal known gate scheme which meets these requirements: the Knill controlled-Z gate, implemented in integrated laser-written waveguide arrays. We show device performance to be less sensitive to phase variations in the circuit than to small deviations in the coupler reflectivity, which are expected given the tolerance values of the fabrication method. The mode fidelity is also shown to be less sensitive to reflectivity and phase errors than the process fidelity. Our best device achieves a fidelity of 0.931 ± 0.001 with the ideal 4 × 4 unitary circuit and a process fidelity of 0.680 ± 0.005 with the ideal computational-basis process.

  10. Multi-photon absorption limits to heralded single photon sources

    PubMed Central

    Husko, Chad A.; Clark, Alex S.; Collins, Matthew J.; De Rossi, Alfredo; Combrié, Sylvain; Lehoucq, Gaëlle; Rey, Isabella H.; Krauss, Thomas F.; Xiong, Chunle; Eggleton, Benjamin J.

    2013-01-01

    Single photons are of paramount importance to future quantum technologies, including quantum communication and computation. Nonlinear photonic devices using parametric processes offer a straightforward route to generating photons, however additional nonlinear processes may come into play and interfere with these sources. Here we analyse spontaneous four-wave mixing (SFWM) sources in the presence of multi-photon processes. We conduct experiments in silicon and gallium indium phosphide photonic crystal waveguides which display inherently different nonlinear absorption processes, namely two-photon (TPA) and three-photon absorption (ThPA), respectively. We develop a novel model capturing these diverse effects which is in excellent quantitative agreement with measurements of brightness, coincidence-to-accidental ratio (CAR) and second-order correlation function g(2)(0), showing that TPA imposes an intrinsic limit on heralded single photon sources. We build on these observations to devise a new metric, the quantum utility (QMU), enabling further optimisation of single photon sources. PMID:24186400

  11. Pathological Laughter as a Symptom of Midbrain Infarction

    PubMed Central

    Dabby, Ron; Watemberg, Nathan; Lampl, Yair; Eilam, Anda; Rapaport, Abraham; Sadeh, Menachem

    2004-01-01

    Pathological laughter is an uncommon symptom usually caused by bilateral, diffuse cerebral lesions. It has rarely been reported in association with isolated cerebral lesions. Midbrain involvement causing pathological laughter is extremely unusual. We describe three patients who developed pathological laughter after midbrain and pontine-midbrain infarction. In two patients a small infarction in the left paramedian midbrain was detected, whereas the third one sustained a massive bilateral pontine infarction extending to the midbrain. Laughter heralded stroke by one day in one patient and occurred as a delayed phenomenon three months after stroke in another. Pathological laughter ceased within a few days in two patients and was still present at a two year follow-up in the patient with delayed-onset laughter. Pathological laughter can herald midbrain infarction or follow stroke either shortly after onset of symptoms or as a delayed phenomenon. Furthermore, small unilateral midbrain infarctions can cause this rare complication. PMID:15706050

  12. Engineering integrated photonics for heralded quantum gates

    PubMed Central

    Meany, Thomas; Biggerstaff, Devon N.; Broome, Matthew A.; Fedrizzi, Alessandro; Delanty, Michael; Steel, M. J.; Gilchrist, Alexei; Marshall, Graham D.; White, Andrew G.; Withford, Michael J.

    2016-01-01

    Scaling up linear-optics quantum computing will require multi-photon gates which are compact, phase-stable, exhibit excellent quantum interference, and have success heralded by the detection of ancillary photons. We investigate the design, fabrication and characterisation of the optimal known gate scheme which meets these requirements: the Knill controlled-Z gate, implemented in integrated laser-written waveguide arrays. We show device performance to be less sensitive to phase variations in the circuit than to small deviations in the coupler reflectivity, which are expected given the tolerance values of the fabrication method. The mode fidelity is also shown to be less sensitive to reflectivity and phase errors than the process fidelity. Our best device achieves a fidelity of 0.931 ± 0.001 with the ideal 4 × 4 unitary circuit and a process fidelity of 0.680 ± 0.005 with the ideal computational-basis process. PMID:27282928

  13. Heralded quantum repeater based on the scattering of photons off single emitters in one-dimensional waveguides

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Song, Guo-Zhu; Zhang, Mei; Ai, Qing

    We propose a heralded quantum repeater based on the scattering of photons off single emitters in one-dimensional waveguides. We show the details by implementing nonlocal entanglement generation, entanglement swapping, and entanglement purification modules with atoms in waveguides, and discuss the feasibility of the repeater with currently achievable technology. In our scheme, the faulty events can be discarded by detecting the polarization of the photons. That is, our protocols are accomplished with a fidelity of 100% in principle, which is advantageous for implementing realistic long-distance quantum communication. Moreover, additional atomic qubits are not required, but only a single-photon medium. Our schememore » is scalable and attractive since it can be realized in solid-state quantum systems. With the great progress on controlling atom-waveguide systems, the repeater may be very useful in quantum information processing in the future.« less

  14. Engineering integrated photonics for heralded quantum gates.

    PubMed

    Meany, Thomas; Biggerstaff, Devon N; Broome, Matthew A; Fedrizzi, Alessandro; Delanty, Michael; Steel, M J; Gilchrist, Alexei; Marshall, Graham D; White, Andrew G; Withford, Michael J

    2016-06-10

    Scaling up linear-optics quantum computing will require multi-photon gates which are compact, phase-stable, exhibit excellent quantum interference, and have success heralded by the detection of ancillary photons. We investigate the design, fabrication and characterisation of the optimal known gate scheme which meets these requirements: the Knill controlled-Z gate, implemented in integrated laser-written waveguide arrays. We show device performance to be less sensitive to phase variations in the circuit than to small deviations in the coupler reflectivity, which are expected given the tolerance values of the fabrication method. The mode fidelity is also shown to be less sensitive to reflectivity and phase errors than the process fidelity. Our best device achieves a fidelity of 0.931 ± 0.001 with the ideal 4 × 4 unitary circuit and a process fidelity of 0.680 ± 0.005 with the ideal computational-basis process.

  15. Variability in sublingual microvessel density and flow measurements in healthy volunteers.

    PubMed

    Hubble, Sheena M A; Kyte, Hayley L; Gooding, Kim; Shore, Angela C

    2009-02-01

    As sublingual microvascular indices are increasingly heralded as new resuscitation end-points, better population data are required to power clinical studies. This paper describes improved methods to quantify sublingual microvessel flow and density in images obtained by sidestream dark field (SDF) technology in healthy volunteers, including vessels under 10 microm in diameter. Measurements of sublingual capillary density and flow were obtained by recording three 15-second images in 20 healthy volunteers over three days. Two independent observers quantified capillary density by using two methods: total vessel length (mm/mm2) and counting (number/mm). Both intraoral and temporal variabilities within subject and observer reproducibilities were determined by using coefficients of variability and reproducibility indices. For small (1-10 microm), medium (11-20 microm), and large (21-50 microm) diameter, mean vessel density with standard deviations (SDs) in volunteers was 21.3(+/- 4.9), 5.2 (+/- 1.2), and 2.7 (+/- 0.9) mm/mm2, respectively. Also, 94.0 +/- 1.4% of small vessels, 94.5 +/- 1.4% of medium vessels, and 94.5+/- 4.0% of large vessels had continuous perfusion. Within subjects, the means of all measurements over three days varied less than 13, 22, and 35% in small, medium, and large vessels, respectively. Interobserver reproducibility was good, especially for capillary (1-10 microm) density and flow measurements. Our methods of microvessel flow and density quantification have low observer variability and confirm the stability of microcirculatory measurements over time. These results facilitate the development of SDF-acquired sublingual microvascular indices as feasible microperfusion markers in shock resuscitation.

  16. Mass spectrometry based proteomics profiling as diagnostic tool in oncology: current status and future perspective.

    PubMed

    Findeisen, Peter; Neumaier, Michael

    2009-01-01

    Proteomics analysis has been heralded as a novel tool for identifying new and specific biomarkers that may improve diagnosis and monitoring of various disease states. Recent years have brought a number of proteomics profiling technologies. Although proteomics profiling has resulted in the detection of disease-associated differences and modification of proteins, current proteomics technologies display certain limitations that are hampering the introduction of these new technologies into clinical laboratory diagnostics and routine applications. In this review, we summarize current advances in mass spectrometry based biomarker discovery. The promises and challenges of this new technology are discussed with particular emphasis on diagnostic perspectives of mass-spectrometry based proteomics profiling for malignant diseases.

  17. Reviewing the technological challenges associated with the development of a laparoscopic palpation device.

    PubMed

    Culmer, Peter; Barrie, Jenifer; Hewson, Rob; Levesley, Martin; Mon-Williams, Mark; Jayne, David; Neville, Anne

    2012-06-01

    Minimally invasive surgery (MIS) has heralded a revolution in surgical practice, with numerous advantages over open surgery. Nevertheless, it prevents the surgeon from directly touching and manipulating tissue and therefore severely restricts the use of valuable techniques such as palpation. Accordingly a key challenge in MIS is to restore haptic feedback to the surgeon. This paper reviews the state-of-the-art in laparoscopic palpation devices (LPDs) with particular focus on device mechanisms, sensors and data analysis. It concludes by examining the challenges that must be overcome to create effective LPD systems that measure and display haptic information to the surgeon for improved intraoperative assessment. Copyright © 2012 John Wiley & Sons, Ltd.

  18. 75 FR 14419 - Camp Tatiyee Land Exchange on the Lakeside Ranger District of the Apache-Sitgreaves National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-25

    ... Ranger, Lakeside Ranger District, Apache-Sitgreaves National Forests, c/o TEC Inc., 514 Via de la Valle... to other papers serving areas affected by this proposal: Tucson Citizen, Sierra Vista Herald, Nogales...

  19. Education--An Annotated Bibliography of Current Issues, July-September, 1989.

    ERIC Educational Resources Information Center

    Wardell, David

    This annotated bibliography of newspaper and magazine articles on a wide variety of topics in education includes entries from the following publications: "Asahi Evening News,""Asian Wall Street Journal,""Daily Yomiuri,""International Herald Tribune,""Japan Times,""Mainichi Daily…

  20. Training Success Stories.

    ERIC Educational Resources Information Center

    Overmeyer-Day, Leslie; Benson, George

    1996-01-01

    Offers case studies of best training practices in leading companies (AEtna, Andersen Worldwide, Boeing, Digital Equipment, Tektronix, Texas Instruments, Allstate, and Sprint), elected by the Benchmarking Forum of the American Society for Training and Development. The practices are technology based and performance oriented and herald common…

  1. CubeSats in Hydrology: Ultrahigh-Resolution Insights Into Vegetation Dynamics and Terrestrial Evaporation

    NASA Astrophysics Data System (ADS)

    McCabe, M. F.; Aragon, B.; Houborg, R.; Mascaro, J.

    2017-12-01

    Satellite-based remote sensing has generally necessitated a trade-off between spatial resolution and temporal frequency, affecting the capacity to observe fast hydrological processes and rapidly changing land surface conditions. An avenue for overcoming these spatiotemporal restrictions is the concept of using constellations of satellites, as opposed to the mission focus exemplified by the more conventional space-agency approach to earth observation. Referred to as CubeSats, these platforms offer the potential to provide new insights into a range of earth system variables and processes. Their emergence heralds a paradigm shift from single-sensor launches to an operational approach that envisions tens to hundreds of small, lightweight, and comparatively inexpensive satellites placed into a range of low earth orbits. Although current systems are largely limited to sensing in the optical portion of the electromagnetic spectrum, we demonstrate the opportunity and potential that CubeSats present the hydrological community via the retrieval of vegetation dynamics and terrestrial evaporation and foreshadow future sensing capabilities.

  2. The growth and potential of human antiviral monoclonal antibody therapeutics.

    PubMed

    Marasco, Wayne A; Sui, Jianhua

    2007-12-01

    Monoclonal antibodies (mAbs) have long provided powerful research tools for virologists to understand the mechanisms of virus entry into host cells and of antiviral immunity. Even so, commercial development of human (or humanized) mAbs for the prophylaxis, preemptive and acute treatment of viral infections has been slow. This is surprising, as new antibody discovery tools have increased the speed and precision with which potent neutralizing human antiviral mAbs can be identified. As longstanding barriers to antiviral mAb development, such as antigenic variability of circulating viral strains and the ability of viruses to undergo neutralization escape, are being overcome, deeper insight into the mechanisms of mAb action and engineering of effector functions are also improving the efficacy of antiviral mAbs. These successes, in both industrial and academic laboratories, coupled with ongoing changes in the biomedical and regulatory environments, herald an era when the commercial development of human antiviral mAb therapies will likely surge.

  3. College Students' Attitude towards Computer Technology

    ERIC Educational Resources Information Center

    Njagi, K. O.; Havice, W. L.

    2011-01-01

    Recent advances in the contemporary world, especially in the area of computer technology, have heralded the development and implementation of new and innovative teaching strategies and particularly with the Internet revolution. This study assessed students' attitude towards computer technology. Specifically, the study assessed differences in…

  4. Toward an International Open Skies Regime: Advances, Impediments, and Impacts

    DOT National Transportation Integrated Search

    1998-01-01

    The International Air Transportation Competition Act of 1979 heralded the era of Open Skies in international aviation. This paper traces the post-war regulation and then deregulation of fares, rates, routes, and capacity all the way from Bermuda I th...

  5. THE NORTH CAROLINA HERALD PILOT STUDY

    EPA Science Inventory



    The sampling design for the National Children's Study (NCS) calls for a population-based, multi-stage, clustered household sampling approach. The full sample is designed to be representative of both urban and rural births in the United States, 2007-2011. While other sur...

  6. 76 FR 50271 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... Interactive Media Glendale, CA 07/20/11 07/12/11 Group (Workers). 80303 Vallejo Times Herald Vallejo, CA 07/20...). 80305 General Advertising Cincinnati, OH........ 07/21/11 07/20/11 Products (State/One-Stop). 80306 JEM...

  7. Albuminuria, Cognitive Functioning and White Matter Hyperintensities in Homebound Elders

    USDA-ARS?s Scientific Manuscript database

    Background: Albuminuria, a kidney marker of microvascular disease, may herald microvascular disease elsewhere, including in the brain. Study Design: Cross sectional. Setting and Participants: Boston, MA (USA) elders receiving home health services to maintain independent living who consented to bra...

  8. Biochar: A synthesis of its agronomic impact beyond carbon sequestration

    USDA-ARS?s Scientific Manuscript database

    Biochar has been recently heralded as an amendment to revitalize degraded soils, improve soil carbon sequestration, increase agronomic productivity and enter into future carbon trading markets. However, scientific and economic technicalities may limit the ability of biochar to consistently deliver o...

  9. Efficient quantum computing using coherent photon conversion.

    PubMed

    Langford, N K; Ramelow, S; Prevedel, R; Munro, W J; Milburn, G J; Zeilinger, A

    2011-10-12

    Single photons are excellent quantum information carriers: they were used in the earliest demonstrations of entanglement and in the production of the highest-quality entanglement reported so far. However, current schemes for preparing, processing and measuring them are inefficient. For example, down-conversion provides heralded, but randomly timed, single photons, and linear optics gates are inherently probabilistic. Here we introduce a deterministic process--coherent photon conversion (CPC)--that provides a new way to generate and process complex, multiquanta states for photonic quantum information applications. The technique uses classically pumped nonlinearities to induce coherent oscillations between orthogonal states of multiple quantum excitations. One example of CPC, based on a pumped four-wave-mixing interaction, is shown to yield a single, versatile process that provides a full set of photonic quantum processing tools. This set satisfies the DiVincenzo criteria for a scalable quantum computing architecture, including deterministic multiqubit entanglement gates (based on a novel form of photon-photon interaction), high-quality heralded single- and multiphoton states free from higher-order imperfections, and robust, high-efficiency detection. It can also be used to produce heralded multiphoton entanglement, create optically switchable quantum circuits and implement an improved form of down-conversion with reduced higher-order effects. Such tools are valuable building blocks for many quantum-enabled technologies. Finally, using photonic crystal fibres we experimentally demonstrate quantum correlations arising from a four-colour nonlinear process suitable for CPC and use these measurements to study the feasibility of reaching the deterministic regime with current technology. Our scheme, which is based on interacting bosonic fields, is not restricted to optical systems but could also be implemented in optomechanical, electromechanical and superconducting systems with extremely strong intrinsic nonlinearities. Furthermore, exploiting higher-order nonlinearities with multiple pump fields yields a mechanism for multiparty mediation of the complex, coherent dynamics.

  10. Children's Sensitivity to Different Modes of Colour Use in Art.

    ERIC Educational Resources Information Center

    O'Hare, D.; Cook, Deborah

    1983-01-01

    Reports on age differences found in children's (1) ability to execute appropriate differences in the uses of color while completing partially drawn scenes; and (2) sensitivity to differences between heraldic, gradation, harmonic, and pure use of color in a matching task. (GC)

  11. 5. View of former Castle Street Wye looking East ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. View of former Castle Street Wye - looking East along Herald Street (formerly Castle Street). To the right is the Massachusetts Turnpike and the tracks of the former B&A R.R. - Boston Elevated Railway, Elevated Mainline, Washington Street, Boston, Suffolk County, MA

  12. Supporting the "Scholarship" in E-Scholarship

    ERIC Educational Resources Information Center

    Borgman, Christine L.

    2008-01-01

    The opportunities of cyberinfrastructure have been both heralded and hyped. The express purpose of cyberinfrastructure is to enable "e-scholarship": new forms of scholarship that are more information-intensive, data-intensive, distributed, collaborative, and multidisciplinary. What does that mean for scholars, for academic libraries, and for…

  13. Joint spectral characterization of photon-pair sources

    NASA Astrophysics Data System (ADS)

    Zielnicki, Kevin; Garay-Palmett, Karina; Cruz-Delgado, Daniel; Cruz-Ramirez, Hector; O'Boyle, Michael F.; Fang, Bin; Lorenz, Virginia O.; U'Ren, Alfred B.; Kwiat, Paul G.

    2018-06-01

    The ability to determine the joint spectral properties of photon pairs produced by the processes of spontaneous parametric downconversion (SPDC) and spontaneous four-wave mixing (SFWM) is crucial for guaranteeing the usability of heralded single photons and polarization-entangled pairs for multi-photon protocols. In this paper, we compare six different techniques that yield either a characterization of the joint spectral intensity or of the closely related purity of heralded single photons. These six techniques include: (i) scanning monochromator measurements, (ii) a variant of Fourier transform spectroscopy designed to extract the desired information exploiting a resource-optimized technique, (iii) dispersive fibre spectroscopy, (iv) stimulated-emission-based measurement, (v) measurement of the second-order correlation function ? for one of the two photons, and (vi) two-source Hong-Ou-Mandel interferometry. We discuss the relative performance of these techniques for the specific cases of a SPDC source designed to be factorable and SFWM sources of varying purity, and compare the techniques' relative advantages and disadvantages.

  14. Boson Sampling with Single-Photon Fock States from a Bright Solid-State Source.

    PubMed

    Loredo, J C; Broome, M A; Hilaire, P; Gazzano, O; Sagnes, I; Lemaitre, A; Almeida, M P; Senellart, P; White, A G

    2017-03-31

    A boson-sampling device is a quantum machine expected to perform tasks intractable for a classical computer, yet requiring minimal nonclassical resources as compared to full-scale quantum computers. Photonic implementations to date employed sources based on inefficient processes that only simulate heralded single-photon statistics when strongly reducing emission probabilities. Boson sampling with only single-photon input has thus never been realized. Here, we report on a boson-sampling device operated with a bright solid-state source of single-photon Fock states with high photon-number purity: the emission from an efficient and deterministic quantum dot-micropillar system is demultiplexed into three partially indistinguishable single photons, with a single-photon purity 1-g^{(2)}(0) of 0.990±0.001, interfering in a linear optics network. Our demultiplexed source is between 1 and 2 orders of magnitude more efficient than current heralded multiphoton sources based on spontaneous parametric down-conversion, allowing us to complete the boson-sampling experiment faster than previous equivalent implementations.

  15. Assessment of undiscovered petroleum resources of the Arctic Alaska Petroleum Province

    USGS Publications Warehouse

    Houseknecht, David W.; Bird, Kenneth J.; Garrity, Christopher P.

    2012-01-01

    The Arctic Alaska Petroleum Province encompasses all lands and adjacent continental shelf areas north of the Brooks Range-Herald arch tectonic belts and south of the northern (outboard) margin of the Alaska rift shoulder. Even though only a small part is thoroughly explored, it is one of the most prolific petroleum provinces in North America, with total known resources (cumulative production plus proved reserves) of about 28 billion barrels of oil equivalent. For assessment purposes, the province is divided into a platform assessment unit, comprising the Alaska rift shoulder and its relatively undeformed flanks, and a fold-and-thrust belt assessment unit, comprising the deformed area north of the Brooks Range and Herald arch tectonic belts. Mean estimates of undiscovered, technically recoverable resources include nearly 28 billion barrels of oil and 122 trillion cubic feet of nonassociated gas in the platform assessment unit and 2 billion barrels of oil and 59 trillion cubic feet of nonassociated gas in the fold-and-thrust belt assessment unit.

  16. Acute tubular necrosis (ATN) presenting with an unusually prolonged period of marked polyuria heralded by an abrupt oliguric phase.

    PubMed

    Ramoutar, Virin; Landa, Cristian; James, Leighton R

    2014-08-22

    A 50-year-old African-American man presented with acute tubular necrosis (ATN) secondary to hypotension from non-typhoid Salmonella gastroenteritis and bacteraemia. The oliguric phase lasted only 24 h followed by prolonged polyuria for 20 days, with urine output in excess of 16 L/day at maximum. As indexed in PubMed this is only the second published case of this nature since 1974, in which an abrupt oliguric phase of 24 h or less heralded prolonged polyuria in ATN. The diagnosis is challenging as fractional excretion of sodium early in the clinical course and rapid normalisation of serum creatinine with intravenous fluids (IVF) may point towards prerenal azotaemia resulting in a premature discharge from hospital. Patients with an abrupt oliguric phase may suffer a secondary renal insult from the profound fluid loss that is to follow and may need inpatient monitoring with supplemental IVF to prevent deleterious outcomes. 2014 BMJ Publishing Group Ltd.

  17. Acute tubular necrosis (ATN) presenting with an unusually prolonged period of marked polyuria heralded by an abrupt oliguric phase

    PubMed Central

    Ramoutar, Virin; Landa, Cristian; James, Leighton R

    2014-01-01

    A 50-year-old African-American man presented with acute tubular necrosis (ATN) secondary to hypotension from non-typhoid Salmonella gastroenteritis and bacteraemia. The oliguric phase lasted only 24 h followed by prolonged polyuria for 20 days, with urine output in excess of 16 L/day at maximum. As indexed in PubMed this is only the second published case of this nature since 1974, in which an abrupt oliguric phase of 24 h or less heralded prolonged polyuria in ATN. The diagnosis is challenging as fractional excretion of sodium early in the clinical course and rapid normalisation of serum creatinine with intravenous fluids (IVF) may point towards prerenal azotaemia resulting in a premature discharge from hospital. Patients with an abrupt oliguric phase may suffer a secondary renal insult from the profound fluid loss that is to follow and may need inpatient monitoring with supplemental IVF to prevent deleterious outcomes. PMID:25150229

  18. Heralded entangling quantum gate via cavity-assisted photon scattering

    NASA Astrophysics Data System (ADS)

    Borges, Halyne S.; Rossatto, Daniel Z.; Luiz, Fabrício S.; Villas-Boas, Celso J.

    2018-01-01

    We theoretically investigate the generation of heralded entanglement between two identical atoms via cavity-assisted photon scattering in two different configurations, namely, either both atoms confined in the same cavity or trapped into locally separated ones. Our protocols are given by a very simple and elegant single-step process, the key mechanism of which is a controlled-phase-flip gate implemented by impinging a single photon on single-sided cavities. In particular, when the atoms are localized in remote cavities, we introduce a single-step parallel quantum circuit instead of the serial process extensively adopted in the literature. We also show that such parallel circuit can be straightforwardly applied to entangle two macroscopic clouds of atoms. Both protocols proposed here predict a high entanglement degree with a success probability close to unity for state-of-the-art parameters. Among other applications, our proposal and its extension to multiple atom-cavity systems step toward a suitable route for quantum networking, in particular for quantum state transfer, quantum teleportation, and nonlocal quantum memory.

  19. Heralded wave packet manipulation and storage of a frequency-converted pair photon at telecom wavelength

    NASA Astrophysics Data System (ADS)

    Kroh, Tim; Ahlrichs, Andreas; Sprenger, Benjamin; Benson, Oliver

    2017-09-01

    Future quantum networks require a hybrid platform of dissimilar quantum systems. Within the platform, joint quantum states have to be mediated either by single photons, photon pairs or entangled photon pairs. The photon wavelength has to lie within the telecommunication band to enable long-distance fibre transmission. In addition, the temporal shape of the photons needs to be tailored to efficiently match the involved quantum systems. Altogether, this requires the efficient coherent wavelength-conversion of arbitrarily shaped single-photon wave packets. Here, we demonstrate the heralded temporal filtering of single photons as well as the synchronisation of state manipulation and detection as key elements in a typical experiment, besides of delaying a photon in a long fibre. All three are realised by utilising commercial telecommunication fibre-optical components which will permit the transition of quantum networks from the lab to real-world applications. The combination of these renders a temporally filtering single-photon storage in a fast switchable fibre loop possible.

  20. A waveguide frequency converter connecting rubidium-based quantum memories to the telecom C-band.

    PubMed

    Albrecht, Boris; Farrera, Pau; Fernandez-Gonzalvo, Xavier; Cristiani, Matteo; de Riedmatten, Hugues

    2014-02-27

    Coherently converting the frequency and temporal waveform of single and entangled photons will be crucial to interconnect the various elements of future quantum information networks. Of particular importance is the quantum frequency conversion of photons emitted by material systems able to store quantum information, so-called quantum memories. There have been significant efforts to implement quantum frequency conversion using nonlinear crystals, with non-classical light from broadband photon-pair sources and solid-state emitters. However, solid state quantum frequency conversion has not yet been achieved with long-lived optical quantum memories. Here we demonstrate an ultra-low-noise solid state photonic quantum interface suitable for connecting quantum memories based on atomic ensembles to the telecommunication fibre network. The interface is based on an integrated-waveguide nonlinear device. We convert heralded single photons at 780 nm from a rubidium-based quantum memory to the telecommunication wavelength of 1,552 nm, showing significant non-classical correlations between the converted photon and the heralding signal.

  1. Telecom-Wavelength Atomic Quantum Memory in Optical Fiber for Heralded Polarization Qubits.

    PubMed

    Jin, Jeongwan; Saglamyurek, Erhan; Puigibert, Marcel lí Grimau; Verma, Varun; Marsili, Francesco; Nam, Sae Woo; Oblak, Daniel; Tittel, Wolfgang

    2015-10-02

    Polarization-encoded photons at telecommunication wavelengths provide a compelling platform for practical realizations of photonic quantum information technologies due to the ease of performing single qubit manipulations, the availability of polarization-entangled photon-pair sources, and the possibility of leveraging existing fiber-optic links for distributing qubits over long distances. An optical quantum memory compatible with this platform could serve as a building block for these technologies. Here we present the first experimental demonstration of an atomic quantum memory that directly allows for reversible mapping of quantum states encoded in the polarization degree of freedom of a telecom-wavelength photon. We show that heralded polarization qubits at a telecom wavelength are stored and retrieved with near-unity fidelity by implementing the atomic frequency comb protocol in an ensemble of erbium atoms doped into an optical fiber. Despite remaining limitations in our proof-of-principle demonstration such as small storage efficiency and storage time, our broadband light-matter interface reveals the potential for use in future quantum information processing.

  2. The New Possibilities from "Big Data" to Overlooked Associations Between Diabetes, Biochemical Parameters, Glucose Control, and Osteoporosis.

    PubMed

    Kruse, Christian

    2018-06-01

    To review current practices and technologies within the scope of "Big Data" that can further our understanding of diabetes mellitus and osteoporosis from large volumes of data. "Big Data" techniques involving supervised machine learning, unsupervised machine learning, and deep learning image analysis are presented with examples of current literature. Supervised machine learning can allow us to better predict diabetes-induced osteoporosis and understand relative predictor importance of diabetes-affected bone tissue. Unsupervised machine learning can allow us to understand patterns in data between diabetic pathophysiology and altered bone metabolism. Image analysis using deep learning can allow us to be less dependent on surrogate predictors and use large volumes of images to classify diabetes-induced osteoporosis and predict future outcomes directly from images. "Big Data" techniques herald new possibilities to understand diabetes-induced osteoporosis and ascertain our current ability to classify, understand, and predict this condition.

  3. Reimagining Critical Theory

    ERIC Educational Resources Information Center

    Rexhepi, Jevdet; Torres, Carlos Alberto

    2011-01-01

    This paper discusses Critical Theory, a model of theorizing in the field of the political sociology of education. We argue for a "reimagined" Critical Theory to herald an empowering, liberatory education that fosters curiosity and critical thinking, and a means for successful bottom-up, top-down political engagement. We present arguments…

  4. Racial Preferences: Doubt in the Priesthood

    ERIC Educational Resources Information Center

    Dent, George W., Jr.

    2008-01-01

    Race preferences and the postmodern version of multiculturalism have always triggered opposition in academia, but it has seldom come from the political left. Now things are changing. Growing unease in the academic "priesthood" over preferences and multiculturalism may herald their end. Longstanding opponents of racial discrimination and identity…

  5. The Pacific Age in World History.

    ERIC Educational Resources Information Center

    Korhonen, Pekka

    1996-01-01

    Tracks the intermittent appearances and variations of the historical concept of a "Pacific Age" from the 1890s to the present. Discusses the social, economic, and historical conditions that resulted in the term's heralding of either economic optimism or racist peril. Suggests these interpretations come in cycles. (MJP)

  6. Persistent immune thrombocytopenia heralds the diagnosis of Mycobacterium chimaera prosthetic valve endocarditis.

    PubMed

    Sacco, Keith A; Burton, M Caroline

    2017-01-01

    A 63 year old female was admitted for investigation of worsening renal insufficiency. During hospitalization she developed persistent immune thrombocytopenia refractory to supportive or immunosuppressive treatment. She was diagnosed with Mycobacterium chimaera prosthetic valve endocarditis and thrombocytopenia resolved with anti-mycobacterial therapy.

  7. Java: An Explosion on the Internet.

    ERIC Educational Resources Information Center

    Read, Tim; Hall, Hazel

    Summer 1995 saw the release, with considerable media attention, of draft versions of Sun Microsystems' Java computer programming language and the HotJava browser. Java has been heralded as the latest "killer" technology in the Internet explosion. Sun Microsystems and numerous companies including Microsoft, IBM, and Netscape have agreed…

  8. A study of the Herald-Phillipstown fault in the Wabash Valley using drillhole and 3-D seismic reflection data

    NASA Astrophysics Data System (ADS)

    Kroenke, Samantha E.

    In June 2009, a 2.2 square mile 3-D high resolution seismic reflection survey was shot in southeastern Illinois in the Phillipstown Consolidated oilfield. A well was drilled in the 3-D survey area to tie the seismic to the geological data with a synthetic seismogram from the sonic log. The objectives of the 3-D seismic survey were three-fold: (1) To image and interpret faulting of the Herald-Phillipstown Fault using drillhole-based geological and seismic cross-sections and structural contour maps created from the drillhole data and seismic reflection data, (2) To test the effectiveness of imaging the faults by selected seismic attributes, and (3) To compare spectral decomposition amplitude maps with an isochron map and an isopach map of a selected geologic interval (VTG interval). Drillhole and seismic reflection data show that various formation offsets increase near the main Herald-Phillipstown fault, and that the fault and its large offset subsidiary faults penetrate the Precambrian crystalline basement. A broad, northeast-trending 10,000 feet wide graben is consistently observed in the drillhole data. Both shallow and deep formations in the geological cross-sections reveal small horst and graben features within the broad graben created possibly in response to fault reactivations. The HPF faults have been interpreted as originally Precambrian age high-angle, normal faults reactivated with various amounts and types of offset. Evidence for strike-slip movement is also clear on several faults. Changes in the seismic attribute values in the selected interval and along various time slices throughout the whole dataset correlate with the Herald-Phillipstown faults. Overall, seismic attributes could provide a means of mapping large offset faults in areas with limited or absent drillhole data. Results of the spectral decomposition suggest that if the interval velocity is known for a particular formation or interval, high-resolution 3-D seismic reflection surveys could utilize these amplitudes as an alternative seismic interpretation method for estimating formation thicknesses. A VTG isopach map was compared with an isochron map and a spectral decomposition amplitude map. The results reveal that the isochron map strongly correlates with the isopach map as well as the spectral decomposition map. It was also found that thicker areas in the isopach correlated with higher amplitude values in the spectral decomposition amplitude map. Offsets along the faults appear sharper in these amplitudes and isochron maps than in the isopach map, possibly as a result of increased spatial sampling.

  9. Mode Engineering of Single Photons from Cavity Spontaneous Parametric Down-Conversion Source and Quantum Dots

    NASA Astrophysics Data System (ADS)

    Paudel, Uttam

    Over the past decade, much effort has been made in identifying and characterizing systems that can form a building block of quantum networks, among which semiconductor quantum dots (QD) and spontaneous parametric down-conversion (SPDC) source are two of the most promising candidates. The work presented in this thesis will be centered on investigating and engineering the mentioned systems for generating customizable single photons. A type-II SPDC source can generate a highly flexible pair of entangled photons that can be used to interface disparate quantum systems. In this thesis, we have successfully implemented a cavity-SPDC source that emits polarization correlated photons at 942 nm with a lifetime of 950-1050ps that mode matches closely with InAs/GaAs QD photons. The source emits 80 photon pairs per second per mW pump power within the 150MHz bandwidth. Though the detection of idler photons, the source is capable of emitting heralded photons with g2?0.5 for up to 40 mW pump power. For a low pump power of 5 mW, the heralded g2 is 0.06, indicating that the system is an excellent heralded single photon source. By directly exciting a single QD with cavity-SPDC photons, we have demonstrated a heralded-absorption of SPDC photons by QD, resulting in the coupling of the two systems. Due to the large pump bandwidth, the emitted source is highly multimode in nature, requiring us to post-filter the downconverted field, resulting in a lower photon pair emission rate. We propose placing an intra-cavity etalon to suppress the multi-mode emissions and increase the photon count rate. Understanding and experimentally implementing two-photon interference (HOM) measurements will be crucial for building a scalable quantum network. A detailed theoretical description of HOM measurements is given and is experimentally demonstrated using photons emitted by QD. Through HOM measurements we demonstrated that the QD sample in the study is capable of emitting indistinguishable photons, with the visibility exceeding 95%. As an alternative approach to modifying the spectral mode of single photons, we performed phase modulation of photons emitted by a QD to generate additional sidebands that are separated by several GHz. By performing HOM measurements, we have shown that the central component and the sidebands are in the superposition states and the spectrally modified photons have a well-preserved indistinguishability. Such spectrally engineered photons can be used for phase-encoded cryptography applications. These experimental results should lay the foundations towards building a scalable hybrid quantum network.

  10. Reflective Writing's Synecdochic Imperative: Process Descriptions Redescribed

    ERIC Educational Resources Information Center

    Jung, Julie

    2011-01-01

    Scholars and teachers within the field of composition have long heralded the merits of reflective writing. Whether written intermittently throughout a course or near the end (typically in the genre of portfolio cover letter), reflective writing assignments are thought to promote cognitive development by helping students become more aware of their…

  11. An introduction to the special issue on ecological sites

    USDA-ARS?s Scientific Manuscript database

    The establishment of the Rangeland Interagency Ecological Site Manual by the Natural Resources Conservation Service (NRCS), Forest Service (FS), and the Bureau of Land Management (BLM) heralds a new era of rangeland management in the United States (http://www.fs.fed.us/biology/soil/Signed_RIESM_2010...

  12. Challenges in Transcribing Multimodal Data: A Case Study

    ERIC Educational Resources Information Center

    Helm, Francesca; Dooly, Melinda

    2017-01-01

    Computer-mediated communication (CMC) once meant principally text-based communication mediated by computers, but rapid technological advances in recent years have heralded an era of multimodal communication with a growing emphasis on audio and video synchronous interaction. As CMC, in all its variants (text chats, video chats, forums, blogs, SMS,…

  13. Designing Dreams or Constructing Contradictions? European Union Multifunctional Policies and the Polish Organic Farm Sector

    ERIC Educational Resources Information Center

    De Master, Kathryn

    2012-01-01

    Analysts have heralded the principle of "multifunctionality" undergirding the European Union's Common Agricultural Policy "Second Pillar" support mechanisms as a "new...and strong paradigm" for agriculture (van der Ploeg and Roep 2003), with the potential to re-embed social, environmental, and ethical concerns into…

  14. Usage Data as Indicators of OER Utility

    ERIC Educational Resources Information Center

    Mardis, Marcia A.; Ambavarapu, Chandrahasa R.

    2017-01-01

    A key component of online and blended learning content, open educational resources, (OER) are heralded in a global movement toward high-quality, affordable, accessible, and personalized education. However, stakeholders have expressed concern about scaling OER use due to a lack of means to ensure a fit between learner, resource, and task. Usage…

  15. Special Considerations with Response to Intervention and Instruction for Students with Diverse Backgrounds

    ERIC Educational Resources Information Center

    Hernandez Finch, Maria E.

    2012-01-01

    Response to Intervention (RtI) has been heralded as having significant promise for improving outcomes, reducing disproportional placement in special education, and making education more culturally responsive for culturally and linguistically diverse (CLD) youth. This article reviews the major recent empirical and qualitative research findings with…

  16. Tocqueville, Garrison, and the Perfection of Journalism.

    ERIC Educational Resources Information Center

    Nord, David Paul

    The 1830s marked a lush first flowering of democratic journalism in America--participatory journalism of the sort that Alexis de Tocqueville heralded. But contrary to standard journalism history, this democratic press had nothing to do with the rise of the penny press; in fact, William Lloyd Garrison's abolitionist paper, "The…

  17. Ubiquitous Learning Environments in Higher Education: A Scoping Literature Review

    ERIC Educational Resources Information Center

    Virtanen, Mari Aulikki; Haavisto, Elina; Liikanen, Eeva; Kääriäinen, Maria

    2018-01-01

    Ubiquitous learning and the use of ubiquitous learning environments heralds a new era in higher education. Ubiquitous learning environments enhance context-aware and seamless learning experiences available from any location at any time. They support smooth interaction between authentic and digital learning resources and provide personalized…

  18. Marking-Out Normalcy and Disability in Higher Education

    ERIC Educational Resources Information Center

    Madriaga, Manuel; Hanson, Katie; Kay, Helen; Walker, Ann

    2011-01-01

    This article advocates for socially just pedagogies in higher education to challenge senses of normalcy that perpetuate elitist academic attitudes towards the inclusion of disabled students. Normalcy is equated here with an everyday eugenics, which heralds a non-disabled person without "defects", or impairments, as the ideal norm. This…

  19. A Mobile Application for Discovery

    ERIC Educational Resources Information Center

    Zylstra, Robert

    2011-01-01

    The last 5 years have heralded a number of important changes to virtual libraries in academic and public settings. Despite this continual effort to improve library catalogs and websites, the fundamentals of these online spaces remain relatively unchanged. Digital collections are within reach of many libraries, yet they remain difficult to…

  20. Neoliberalism and Corporate School Reform: "Failure" and "Creative Destruction"

    ERIC Educational Resources Information Center

    Saltman, Kenneth J.

    2014-01-01

    In the United States, corporate school reform or neoliberal educational restructuring has overtaken educational policy, practice, curriculum, and nearly all aspects of educational reform. Although this movement began on the political right, the corporate school model has been heralded across the political spectrum and is aggressively embraced now…

  1. Towards a Philosophy of Academic Publishing

    ERIC Educational Resources Information Center

    Peters, Michael A.; Jandric, Petar; Irwin, Ruth; Locke, Kirsten; Devine, Nesta; Heraud, Richard; Gibbons, Andrew; Besley, Tina; White, Jayne; Forster, Daniella; Jackson, Liz; Grierson, Elizabeth; Mika, Carl; Stewart, Georgina; Tesar, Marek; Brighouse, Susanne; Arndt, Sonja; Lazaroiu, George; Mihaila, Ramona; Legg, Catherine; Benade, Leon

    2016-01-01

    This article is concerned with developing a philosophical approach to a number of significant changes to academic publishing, and specifically the global journal knowledge system wrought by a range of new digital technologies that herald the third age of the journal as an electronic, interactive and mixed-media form of scientific communication.…

  2. An Empirical Assessment of Interdisciplinarity: Perspectives from Graduate Students and Program Administrators

    ERIC Educational Resources Information Center

    Shandas, Vivek; Brown, Stephan Edward

    2016-01-01

    Interdisciplinarity is heralded as a relatively new educational and research paradigm that can effectively address complex problems at disciplinary boundaries. Yet little is known about the extent to which interdisciplinarity has penetrated higher education, nor about how students and program administrators view its usefulness. Through a case…

  3. Immersive Planetarium Visualizations for Teaching Solar System Moon Concepts to Undergraduates

    ERIC Educational Resources Information Center

    Yu, Ka Chun; Sahami, Kamran; Denn, Grant; Sahami, Victoria; Sessions, Larry C.

    2016-01-01

    Digital video fulldome has long been heralded as a revolutionary educational technology; yet the discipline-based astronomy education research literature showing planetarium effectiveness has been sparse. In order to help understand to what extent immersion impacts learning and the effect of the "narrative journey" model of presentation,…

  4. Making Way for Equity: Elementary Principals' Interpretations of Equity

    ERIC Educational Resources Information Center

    Fishman, Christine A.

    2010-01-01

    Treating education as a socially transformative and morally conscious enterprise calls for educators to expose and improve social conditions related to oppression. These beliefs herald a different kind of practice for teachers and administrators in public schools, a practice that deals directly with dilemmas of equity and pluralism. Limited…

  5. Pessimism vs. Existentialism

    ERIC Educational Resources Information Center

    Solomon, Robert C.

    2007-01-01

    So opined Adam Cohen recently in the "International Herald Tribune", and so, too, according to a recent book by Joshua Foa Dienstag, a political scientist at the University of California at Los Angeles, "Pessimism: Philosophy, Ethic, Spirit "(Princeton University Press, 2006). In his defense of pessimism as an appropriate and realistic philosophy,…

  6. Feedback for Thought: Examining the Influence of Feedback Constituents on Learning Experience

    ERIC Educational Resources Information Center

    Aoun, Chadi; Vatanasakdakul, Savanid; Ang, Karyne

    2018-01-01

    Reflective teaching practice is often heralded as a pillar of effective tuition. However, the perceptions of multiple forms of feedback among learners and their contributions to reflective learning is yet to attract significant attention, particularly in the Information Systems (IS) context. This research investigates the antecedent constituents…

  7. Heralding the Other: Sousa, Simulacra, and Settler Colonialism

    ERIC Educational Resources Information Center

    Graham, Matthew C.

    2016-01-01

    This paper addresses the role of music and music education in the perpetuation of settler colonialism (a particular colonial configuration predicated on the expulsion of indigenous people and occupation of indigenous land) within the United States. Using Baudrillard's notion of simulacra, or "false truths," to look at racialized…

  8. Reducing Bullying: Application of Social Cognitive Theory

    ERIC Educational Resources Information Center

    Swearer, Susan M.; Wang, Cixin; Berry, Brandi; Myers, Zachary R.

    2014-01-01

    Social cognitive theory (SCT) is an important heuristic for understanding the complexity of bullying behaviors and the social nature of involvement in bullying. Bullying has been heralded as a social relationship problem, and the interplay between the individual and his or her social environment supports this conceptualization. SCT has been used…

  9. CARBON, NITROGEN, PHOSPHORUS AND HEAVY METAL BUDGETS: HOW LARGE IS THE EELGRASS (ZOSTERA MARINA L.) SINK IN A TEMPERATE ESTUARY?

    EPA Science Inventory

    Seagrasses are often heralded as sentinel or indicator species because they are long-lived and integrate biological, physical and chemical parameters (Schlacher-Hoenlinger and Schlacher, 1998; Hoven et al., 1999; Pergent-Martini and Pergent, 2000). Several studies have shown ...

  10. 75 FR 81892 - Changes in Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ..., 500 San Sebastian View, St. Augustine, FL 32084. Hawaii: Hawaii (FEMA Docket No.: B- Unincorporated areas April 16, 2010; The Honorable William P. August 23, 2010 155166 1124) of Hawaii County (09- April 23, 2010; Kenoi, Mayor, Hawaii 09-1398P). Hawaii Tribune- County, 25 Aupuni Herald. Street, Hilo, HI...

  11. Web-Based Training in Corporations: Organizational Considerations

    ERIC Educational Resources Information Center

    Chamers, Terri; Lee, Doris

    2004-01-01

    Advances in technology offer the possibility of new methods for delivering instruction. Learning via the Internet is being heralded by many as the new pedagogical model for training. Recent issues of training, computer, and management magazines all suggest that web-based training (WBT) is the best way to reach geographically dispersed employees…

  12. Podcasting as Transformative Work

    ERIC Educational Resources Information Center

    Vasquez, Vivian Maria

    2015-01-01

    Although technology is most often heralded an intrinsic efficiency, the process of using technology to create a text is full of opportunities to learn new information, create and distribute knowledge, and engage in identity work. This article explores how the production of 1 such technological text, a podcast, offered students opportunities to…

  13. Will the Real Digital Native Please Stand Up?

    ERIC Educational Resources Information Center

    Waters, John K.

    2011-01-01

    A decade has passed since author, game designer, and educational thought leader Marc Prensky heralded the arrival of a new generation of students whose immersion in information technology distinguished them in fundamental ways from previous generations. Because they had spent their entire lives "surrounded by and using computers, videogames,…

  14. The Politics of Youthful Antipolitics: Representing the "Issue" of Youth Participation in Politics

    ERIC Educational Resources Information Center

    Farthing, Rys

    2010-01-01

    Young people's relationship with contemporary politics is complex and often problematized. They are often chastised as the apolitical harbingers of an incipient "crisis of democracy" while simultaneously heralded as the authors of sophisticated new forms of politics, most notably within electronic realms. Previous literature examining…

  15. Comparing Assessments within Junior Geography Textbooks Used in Mainland China

    ERIC Educational Resources Information Center

    Yang, Daihu

    2013-01-01

    The 2001 Geography Standards for Junior Secondary Schools are the first national standards for geographic education since the founding of Communist China. The standards heralded several new ideas for geographic education, and textbook assessments are one important way for understanding their impact. This study examines the changes in assessments…

  16. Limiting Regret: Building the Army We Will Need

    DTIC Science & Technology

    2015-01-01

    Rise of Taliban,” London Sunday Times, October 12, 2008; Lolita C. Baldor, “General: Urgent Need for Troops in Afghanistan Now,” Miami Herald...See Lolita C. Baldor, “War Demands Strain Military Readiness,” USA Today, February 9, 2008; Tom Philpott, “Mullen: Money Crisis Will Impact

  17. The Unintended Consequences of Reorganization

    ERIC Educational Resources Information Center

    Zeng, Jie

    2009-01-01

    For the last five years, the lives of New York City (NYC) public school educators have been governed by constant change. With certainty, every January or June heralded something new--restructured departments and offices, staff changes and new initiatives. One of the most interesting chapters in the history of the NYC school system unfolded in the…

  18. The U.S. Army's Impact on the History of Distance Education

    ERIC Educational Resources Information Center

    Duncan, Steve

    2005-01-01

    One of the most significant events that heralded the Department of Defense's commitment to distance education was the Advanced Distributed Learning (ADL) Initiative, which held its kickoff meeting in Washington, DC in 1997. This meeting provided the army and other military services the endorsement that had been lacking relative to implementing…

  19. Tillage and cover cropping effects on soil properties and crop production in Illinois

    USDA-ARS?s Scientific Manuscript database

    Cover crops (CCs) have been heralded for their potential to improve soil properties, retain nutrients in the field, and increase subsequent crop yields yet support for these claims within the state of Illinois remains limited. We assessed the effects of integrating five sets of CCs into a corn-soybe...

  20. Enacting Critical Pedagogy in an Emerging South African Democracy: Narratives of Pleasure and Pain

    ERIC Educational Resources Information Center

    Perumal, Juliet

    2016-01-01

    "Education Before Liberation" became the mantra of the struggle against apartheid oppression in South Africa. Apartheid policies predestined the Black majority to servitude and dehumanization. The advent of democracy heralded a plethora of transformative curriculum policies with the express intent to counter the destiny that the…

  1. 2013 Inaugural Parade

    NASA Image and Video Library

    2013-01-21

    Members of The U.S. Army Band, Herald Trumpets Ensemble, look to make sure their feet are on markers in front of the Preidential viewing stand ahead of the 2013 Inauguration Parade, Monday, Jan. 21, 2013 in Washington. President Barack Obama was sworn-in as the nation's 44th President earlier in the day. Photo Credt: (NASA/Bill Ingalls)

  2. New Data, Old Tensions: Big Data, Personalized Learning, and the Challenges of Progressive Education

    ERIC Educational Resources Information Center

    Dishon, Gideon

    2017-01-01

    Personalized learning has become the most notable application of big data in primary and secondary schools in the United States. The combination of big data and adaptive technological platforms is heralded as a revolution that could transform education, overcoming the outdated classroom model, and realizing the progressive vision of…

  3. 78 FR 60892 - Outer Continental Shelf (OCS), Alaska OCS Region, Chukchi Sea Planning Area, Proposed Oil and Gas...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ..., concerning the importance of these areas or associated activities. 6. Submissions of Nominations, Requests... range of interest classifications and anticipated activity regarding the nominated area(s). Interested... on the importance of Hanna Shoal and Herald Shoal. While already excluded from the Program Area...

  4. Catching Up on Algebra

    ERIC Educational Resources Information Center

    Cavanagh, Sean

    2008-01-01

    A popular humorist and avowed mathphobe once declared that in real life, there's no such thing as algebra. Kathie Wilson knows better. Most of the students in her 8th grade class will be thrust into algebra, the definitive course that heralds the beginning of high school mathematics, next school year. The problem: Many of them are about three…

  5. The Effect of Changing American Social Values on the Editorial Content, Style and Management of Newspapers.

    ERIC Educational Resources Information Center

    Downes, Donna Roman

    An examination of the "Los Angeles Times," the "Long Beach Independent Press-Telegram," the "Register," and the "Herald Examiner" as well as personal interviews conducted at the editorial and management levels reveal the effect of changing American social values. Changing values can be marked by such broad…

  6. The Reporter's Privilege under Fire: Is the American Press Still Free?

    ERIC Educational Resources Information Center

    West, Natalie

    2009-01-01

    The First Amendment's guarantee of an independent press that may freely collect and disseminate news is often considered the bedrock of American democracy. Yet more than a century and a half after the "New York Herald's" John Nugent became the first American reporter jailed for refusing to identify a confidential source, reporters…

  7. Teaching English in a Multilingual Context: The Algerian Case.

    ERIC Educational Resources Information Center

    Miliani, Mohamed

    2001-01-01

    Algeria's educational system and language usage are politically controlled. As French loses its ground, English is being heralded as a solution to the country's problems. Popular vernaculars are banned. Language policy is the result of political takeovers. The introduction of English in elementary school appears to be an attempt to end the…

  8. Children's Sensitivity to Different Modes of Colour Use in Art.

    ERIC Educational Resources Information Center

    O'Hare, D.; Cook, Deborah

    1983-01-01

    Reviews studies of children's drawings and summarizes experiment which tested 5- to 11-year-olds for ability to execute color use differences and sensitivity to differences in heraldic, gradation, harmonic, and pure color use. It was found that children go from being completely unable to consistently able to produce appropriate differences. (MBR)

  9. Health and Environmental Science: A Brief Review

    DOE R&D Accomplishments Database

    1982-09-27

    The detonation of the first atomic bomb heralded the beginning of a new age. Almost everyone agreed that the enormous energy released by the "atomic reaction" would create opportunities and problems far larger than man faced in previous history. However, few foresaw the explosion of knowledge that would also be part of this new age.

  10. The Press and Authority: Portrayals of a Coach and a Mayor. Journalism Monographs No. 50.

    ERIC Educational Resources Information Center

    Paletz, David L.; LaFiura, Dennis

    This monograph investigates the relationship between media and personal authority. Specifically, the nature and possible effects of coverage by the Durham, North Carolina, "Morning Herald" of Duke University's former basketball coach, Raymond C. (Bucky) Waters, are compared to its treatment of a more conventional political…

  11. Ghosts, Meaning, and Faith: After-Death Communications in Bereavement Narratives

    ERIC Educational Resources Information Center

    Kwilecki, Susan

    2011-01-01

    After-death communications (ADCs) are reported encounters with a deceased loved one, a contemporary type of ghost experience heralded as therapeutic in coping with bereavement. Pertinent literature generally illustrates the healing power of ADCs with brief, self-contained episodes. The functions of ADCs over the course of grief need exploration.…

  12. Politics Threaten Efforts to Improve K-12 Education

    ERIC Educational Resources Information Center

    Marchitello, Max

    2014-01-01

    Beginning in 2010, more than 40 states adopted the Common Core State Standards. In the years immediately following their adoption, educators, parents, and policymakers familiar with the standards strongly supported them. Both Republicans and Democrats heralded the Common Core as one of the most promising school reforms in decades. Fast forward to…

  13. Does Early Paternal Parenting Promote Low-Income Children's Long-Term Cognitive Skills?

    ERIC Educational Resources Information Center

    Coley, Rebekah Levine; Lewin-Bizan, Selva; Carrano, Jennifer

    2011-01-01

    Although scholars and policy makers herald the promotive influence of fathers' parenting involvement, limited research has carefully delineated effects of fathers' parenting on low-income children's development and whether early contributions from fathers confer long-term protective effects. Using data from the Three-City Study (N = 261), analyses…

  14. Learning with Portable Digital Devices in Australian Schools: 20 Years On!

    ERIC Educational Resources Information Center

    Newhouse, C. Paul

    2014-01-01

    Portable computing technologies such as laptops, tablets, smartphones, wireless networking, voice/stylus input, and plug and play peripheral devices, appear to offer the means of finally realising much of the long heralded vision for computers to support learning in schools. There is the possibility for the technology to finally become a…

  15. Neoliberal Competition in Higher Education Today: Research, Accountability and Impact

    ERIC Educational Resources Information Center

    Olssen, Mark

    2016-01-01

    Drawing on Foucault's elaboration of neoliberalism as a positive form of state power, the ascendancy of neoliberalism in higher education in Britain is examined in terms of the displacement of public good models of governance, and their replacement with individualised incentives and performance targets, heralding new and more stringent conceptions…

  16. The next Exclusion Debate: Assessing Technology, Ethics, and Intellectual Disability after the Human Genome Project

    ERIC Educational Resources Information Center

    Munger, Kelly M.; Gill, Carol J.; Ormond, Kelly E.; Kirschner, Kristi L.

    2007-01-01

    Recent scientific discoveries have made it much easier to test prenatally for various genetic disabilities, such as Down syndrome. However, while many observers have heralded such "advances" for their effectiveness in detecting certain conditions, others have argued that they perpetuate discrimination by preventing the birth of children with…

  17. Tools to exploit sequence data to find new markers and disease loci in dairy cattle

    USDA-ARS?s Scientific Manuscript database

    The decrease in cost of Next-Generation Sequencing has brought the technology into the realm of practical applications in livestock genomics. Recently, the 1000 Bulls Project has heralded the possibility of using full sequence data to improve imputation and detect disease loci within select founder ...

  18. "Balancing Open Doors and National Security"

    ERIC Educational Resources Information Center

    Branch-Brioso, Karen

    2009-01-01

    While the number of exchange visas for international students and professors is up overall, the post-Sept. 11 decline continues for many majority-Muslim countries. Last November, the U.S. Department of State heralded a record high number of visas issued to international students and exchange visitors. A report by the Institute of International…

  19. Tackling Knowledge "Like a Business?" Rethinking the Modernisation of Higher Education in Poland

    ERIC Educational Resources Information Center

    Bates, Agnieszka; Godon, Rafal

    2017-01-01

    The year 1989 marked the official end of communist rule in Poland and the replacement of "Gosplan" by new instruments for liberal-democratic governance. In terms of the economy this heralded a departure from Gosplan's five-year planning cycles, performance targets and the "propaganda of success." Paradoxically, however, 27…

  20. The Privatization of Public Education

    ERIC Educational Resources Information Center

    Hunter, Richard

    2010-01-01

    For-profit education is not a new focus for public schools in the United States. It has been around for several decades, has stimulated considerable controversy, and has been heralded by some as a panacea for improving learning for the nation's public school students. For-profit schools are run by private, for-profit companies or organizations…

  1. Prime time for turtle conservation

    Treesearch

    A. Ross Kiester; Deanna H. Olson

    2011-01-01

    Our turtle heritage is diminishing at a rate outpacing that of other main animal groups. The 2011-Year of the Turtle partnership and campaign is an opportunity to raise awareness for turtles, celebrate our turtle heritage, herald conservation and research successes, and identify gaps in our understanding that can be the focus of future work. We outline seven...

  2. Cultural Flashpoint: The Politics of Teacher Education Reform in Ireland

    ERIC Educational Resources Information Center

    Conway, Paul F.

    2013-01-01

    The publication of the Programme for International Student Assessment (PISA) 2009 (Cosgrove et al., 2010; Perkins et al., 2010) reading literacy results heralded a crisis of confidence in educational standards in Ireland. This article examines the national and international context of teacher education reform and the politics of the policy…

  3. Exclusion from School and Recognition of Difference

    ERIC Educational Resources Information Center

    McCluskey, Gillean; Riddell, Sheila; Weedon, Elisabet; Fordyce, Mariela

    2016-01-01

    There has been an overall decrease in exclusion rates and numbers in recent years across the UK. This change has often been heralded as evidence that national inclusion policies are "working" and that schools themselves are becoming increasingly inclusive. This article examines findings from a recent study on school exclusion in Wales,…

  4. Learning Styles and Computers.

    ERIC Educational Resources Information Center

    Geisert, Gene; Dunn, Rita

    Although the use of computers in the classroom has been heralded as a major breakthrough in education, many educators have yet to use computers to their fullest advantage. This is perhaps due to the traditional assumption that students differed only in their speed of learning. However, new research indicates that students differ in their style of…

  5. Our Visible Work: Community & Collaboration in an Educator Inquiry Group

    ERIC Educational Resources Information Center

    Clark, Margaret R.

    2016-01-01

    Early childhood education has recently been heralded as the cornerstone of a brighter future for the United States, playing an important role in the healthy development of our youngest children (Perry, 2015; Bornfreund, 2015). However, the teachers of these children face multiple challenges in the profession, including unlivable wages, low morale…

  6. Beyond Social Constructivist Perspectives on Assessment: The Centring of Knowledge

    ERIC Educational Resources Information Center

    Shay, Suellen

    2008-01-01

    Over the past few decades assessment has been heralded for its key role in the improvement of teaching and learning. However, more recently there have been expressions of uncertainty about whether assessment is in fact delivering on its promised potential. Against this backdrop of uncertainty and circumspection this paper offers a critical…

  7. To Segregate or to Separate? Special Education Expansion and Divergence in the United States and Germany

    ERIC Educational Resources Information Center

    Powell, Justin J. W.

    2009-01-01

    Over the past two hundred years in the United States and Germany, special educational systems have been institutionalized to facilitate access to learning opportunities for children with disabilities, difficulties, and disadvantages. Originally heralded as innovative, the positive views of these mainly segregating and separating educational…

  8. Leadership Legacies

    ERIC Educational Resources Information Center

    Grady, Marilyn L.

    2006-01-01

    Recent obituaries and testimonials to Coretta Scott King and Wendy Wasserstein are reminders of the leadership legacies of these women. About Coretta Scott King (1927-2006), Burch in "The Miami Herald" (February 1, 2006) stated "Coretta Scott King built a legacy from pain and progress, first as the wife who stood tall next to a man bent on…

  9. Toward a Contextual Theological Reading of John Amos Comenius

    ERIC Educational Resources Information Center

    Glenn, Justin

    2016-01-01

    John Amos Comenius developed a revolutionary philosophy of education in seventeenth-century Europe. He argued for ideas such as universal education, which was virtually unheard of in his time but has become standard in modern western society. In the middle of the twentieth century, Comenius's ideas were heralded in the secular educational…

  10. Professionals' Perception of Quality Physical Education Learning in Selected Asian Cities

    ERIC Educational Resources Information Center

    Ho, Walter King Yan; Ahmed, Md. Dilsad; Keh, Nyit Chin; Khoo, Selina; Tan, Cheehian; Dehkordi, Mitra Rouhi; Gallardo, Mila; Lee, Kicheon; Yamaguchi, Yasuo; Wang, Jian; Liu, Min; Huang, Fan

    2017-01-01

    Numerous studies have been published heralding the benefits of physical education in school education. Sport and physical activities form the major content in learning and the arrangement serves as the major source of development in students. This paper identifies "quality" as an internationally concerned issue and within the concept,…

  11. A Brief History of ... Semiconductors

    ERIC Educational Resources Information Center

    Jenkins, Tudor

    2005-01-01

    The development of studies in semiconductor materials is traced from its beginnings with Michael Faraday in 1833 to the production of the first silicon transistor in 1954, which heralded the age of silicon electronics and microelectronics. Prior to the advent of band theory, work was patchy and driven by needs of technology. However, the arrival…

  12. Round-robin differential-phase-shift quantum key distribution with heralded pair-coherent sources

    NASA Astrophysics Data System (ADS)

    Wang, Le; Zhao, Shengmei

    2017-04-01

    Round-robin differential-phase-shift (RRDPS) quantum key distribution (QKD) scheme provides an effective way to overcome the signal disturbance from the transmission process. However, most RRDPS-QKD schemes use weak coherent pulses (WCPs) as the replacement of the perfect single-photon source. Considering the heralded pair-coherent source (HPCS) can efficiently remove the shortcomings of WCPs, we propose a RRDPS-QKD scheme with HPCS in this paper. Both infinite-intensity decoy-state method and practical three-intensity decoy-state method are adopted to discuss the tight bound of the key rate of the proposed scheme. The results show that HPCS is a better candidate for the replacement of the perfect single-photon source, and both the key rate and the transmission distance are greatly increased in comparison with those results with WCPs when the length of the pulse trains is small. Simultaneously, the performance of the proposed scheme using three-intensity decoy states is close to that result using infinite-intensity decoy states when the length of pulse trains is small.

  13. Driven Boson Sampling.

    PubMed

    Barkhofen, Sonja; Bartley, Tim J; Sansoni, Linda; Kruse, Regina; Hamilton, Craig S; Jex, Igor; Silberhorn, Christine

    2017-01-13

    Sampling the distribution of bosons that have undergone a random unitary evolution is strongly believed to be a computationally hard problem. Key to outperforming classical simulations of this task is to increase both the number of input photons and the size of the network. We propose driven boson sampling, in which photons are input within the network itself, as a means to approach this goal. We show that the mean number of photons entering a boson sampling experiment can exceed one photon per input mode, while maintaining the required complexity, potentially leading to less stringent requirements on the input states for such experiments. When using heralded single-photon sources based on parametric down-conversion, this approach offers an ∼e-fold enhancement in the input state generation rate over scattershot boson sampling, reaching the scaling limit for such sources. This approach also offers a dramatic increase in the signal-to-noise ratio with respect to higher-order photon generation from such probabilistic sources, which removes the need for photon number resolution during the heralding process as the size of the system increases.

  14. Influencing agent group behavior by adjusting cultural trait values.

    PubMed

    Tuli, Gaurav; Hexmoor, Henry

    2010-10-01

    Social reasoning and norms among individuals that share cultural traits are largely fashioned by those traits. We have explored predominant sociological and cultural traits. We offer a methodology for parametrically adjusting relevant traits. This exploratory study heralds a capability to deliberately tune cultural group traits in order to produce a desired group behavior. To validate our methodology, we implemented a prototypical-agent-based simulated test bed for demonstrating an exemplar from intelligence, surveillance, and reconnaissance scenario. A group of simulated agents traverses a hostile territory while a user adjusts their cultural group trait settings. Group and individual utilities are dynamically observed against parametric values for the selected traits. Uncertainty avoidance index and individualism are the cultural traits we examined in depth. Upon the user's training of the correspondence between cultural values and system utilities, users deliberately produce the desired system utilities by issuing changes to trait. Specific cultural traits are without meaning outside of their context. Efficacy and timely application of traits in a given context do yield desirable results. This paper heralds a path for the control of large systems via parametric cultural adjustments.

  15. Heralded creation of photonic qudits from parametric down-conversion using linear optics

    NASA Astrophysics Data System (ADS)

    Yoshikawa, Jun-ichi; Bergmann, Marcel; van Loock, Peter; Fuwa, Maria; Okada, Masanori; Takase, Kan; Toyama, Takeshi; Makino, Kenzo; Takeda, Shuntaro; Furusawa, Akira

    2018-05-01

    We propose an experimental scheme to generate, in a heralded fashion, arbitrary quantum superpositions of two-mode optical states with a fixed total photon number n based on weakly squeezed two-mode squeezed state resources (obtained via weak parametric down-conversion), linear optics, and photon detection. Arbitrary d -level (qudit) states can be created this way where d =n +1 . Furthermore, we experimentally demonstrate our scheme for n =2 . The resulting qutrit states are characterized via optical homodyne tomography. We also discuss possible extensions to more than two modes concluding that, in general, our approach ceases to work in this case. For illustration and with regards to possible applications, we explicitly calculate a few examples such as NOON states and logical qubit states for quantum error correction. In particular, our approach enables one to construct bosonic qubit error-correction codes against amplitude damping (photon loss) with a typical suppression of √{n }-1 losses and spanned by two logical codewords that each correspond to an n -photon superposition for two bosonic modes.

  16. OxyContin: Prescription Drug Abuse. CSAT Advisory.

    ERIC Educational Resources Information Center

    Substance Abuse and Mental Health Services Administration (DHHS/PHS), Rockville, MD. Center for Substance Abuse Treatment.

    Recently, the media have issued numerous reports about the apparent increase in OxyContin abuse and addiction. OxyContin has been heralded as a miracle drug that allows patients with chronic pain to resume a normal life. It has also been called pharmaceutical heroin and is thought to have been responsible for a number of deaths and robberies in…

  17. 2 Dailies Battle for Readers and Advertisers in U. of Wisconsin Student-Newspaper War.

    ERIC Educational Resources Information Center

    Hirschorn, Michael W.

    1987-01-01

    Two student newspapers at the University of Wisconsin at Madison are in fierce competition for readers and advertisers. A proposal of the Badger Herald, an 18-year-old conservative weekly, that the two merge their financial operations was rejected by the liberal Daily Cardinal and the newspaper war was on. (MLW)

  18. Special Issue: Stonewall's Legacy--Bisexual, Gay, Lesbian, and Transgender Students in Higher Education

    ERIC Educational Resources Information Center

    Marine, Susan

    2011-01-01

    This monograph explores the progress being made on American college campuses, particularly four-year colleges and universities, through the lens of change in the time since the Stonewall riots happened in June 1969. Frequently heralded as the opening salvo in the war against oppression of bisexual, gay, lesbian, and transgender (BGLT) people and…

  19. MOOCifying Courses: Delivery of a MOOC to Enhance University Course Activities

    ERIC Educational Resources Information Center

    Ostashewski, Nathaniel; Howell, Jennifer; Dron, Jon

    2017-01-01

    Since 2012 MOOCs have been heralded as a new way of learning outside of formal university programs of study and there has been much speculation regarding their impact. While MOOCs have provided millions of global learners with access to courses, they failed to deliver the types of learning experiences and completion requirements that were hoped…

  20. Creativity: Performativity's Poison or Its Antidote?

    ERIC Educational Resources Information Center

    Munday, Ian

    2014-01-01

    A common move in the study of creativity and performativity is to present the former as an antidote to the latter. Might we, therefore, see work on creativity in education as heralding an era of post-performativity? In this paper I argue that the portrayal of performativity in the literature on creativity presents an overly simplistic (vulgar?)…

  1. 75 FR 21394 - Endangered and Threatened Wildlife and Plants; Final Revised Critical Habitat for Hine's Emerald...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... critical habitat units are located in Cook, DuPage, and Will Counties in Illinois; Alpena, Mackinac, and... News- Graphic, St. Ignace News, Door County Advocate, Alpena News, Ozaukee Press, and Joliet Herald... commenter asserts that there is little (if any) economic activity in Alpena, Mackinac, or Presque Isle...

  2. What Do They Want?: A Study of Changing Employer Expectations of Information Professionals

    ERIC Educational Resources Information Center

    Kennan, Mary Anne; Willard, Patricia; Wilson, Concepcion S.

    2006-01-01

    This paper reports the findings of an exploratory study of position vacant announcements appropriate for library and information studies (LIS) graduates appearing in the "Sydney Morning Herald" over a four week period in each of the following years: 2004, 1994, 1984 and 1974. The period studied witnessed change-demanding developments in…

  3. The Place and Approach of Outdoor Learning within a Holistic Curricular Agenda: Development of Singaporean Outdoor Education Practice

    ERIC Educational Resources Information Center

    Atencio, Matthew; Tan, Yuen Sze Michelle; Ho, Susanna; Ching, Chew Ting

    2015-01-01

    This paper details the potential contribution of outdoor education (OE) in Singaporean education given the recent raft of national curricular reforms aimed at fostering holistic and exploratory learning opportunities. In this context, we contend that increasing recognition of the value of OE, both internationally and locally, heralds specific…

  4. New Zealand Perspectives on Early Childhood Education: Naku Te Rourou Nau Te Rourou Ka Ora Ai Te Iwi

    ERIC Educational Resources Information Center

    Tesar, Marek

    2016-01-01

    This special issue focuses on histories, pedagogies, policies, philosophies and alternative perspectives in early childhood education. "Te Whariki" is heralded as the first bicultural curriculum not only in New Zealand, but in the world. Its importance is reflected in national and international research and early childhood discourses.…

  5. Teach for America and the Politics of Progressive Neoliberalism

    ERIC Educational Resources Information Center

    Lahann, Randall; Reagan, Emilie Mitescu

    2011-01-01

    Teach for America (TFA), a non-profit organization designed to recruit recent college graduates to commit two years to teach in understaffed urban and rural schools across the country, has been heralded by private organizations and state agencies as a poster child for alternative pathways to teaching. However, at the same time, TFA has also been…

  6. The Impact of Authentic Learning on Students' Engagement with Physics

    ERIC Educational Resources Information Center

    Murphy, Patricia; Lunn, Stephen; Jones, Helen

    2006-01-01

    The changes in the statutory science curriculum specification for all students aged 14-15 in England and Wales in 2006 herald a shift in how curriculum content is organized, and the purposes for science learning. In a curriculum for scientific literacy the selection of social situations and scientific controversies determines the knowledge that is…

  7. Science Teachers Accelerated Programme Model: A Joint Partnership in the Pacific Region

    ERIC Educational Resources Information Center

    Sharma, Bibhya; Lauano, Faatamali'i Jenny; Narayan, Swasti; Anzeg, Afshana; Kumar, Bijeta; Raj, Jai

    2018-01-01

    The paper heralds a new pedagogical model known as the Science Teachers Accelerated Programme as a platform to upgrade the qualifications of secondary school science teachers throughout the Pacific region. Based on a tripartite partnership between a higher education provider, a regional government and a cohort of science teachers, the model offers…

  8. Bounded and Unbounded Knowledge: Teaching and Learning in a Web 2 World

    ERIC Educational Resources Information Center

    Nagy, Judy; Bigum, Chris

    2007-01-01

    In the recent past, the proliferation of digitally available content heralded the beginning of serious problems for the business models of publishers. The ease with which content can be accessed, copied and distributed disrupts the control of those whose role has been to manage and profit from the intellectual property rights of content producers.…

  9. A Cultural, Linguistic, and Ecological Framework for Response to Intervention with English Language Learners

    ERIC Educational Resources Information Center

    Brown, Julie Esparza; Doolittle, Jennifer

    2008-01-01

    Response to Intervention (RTI) has been heralded by many as the long-awaited alternative to using a discrepancy formula for special education eligibility decisions. RTI focuses on intervening early through a multi-tiered approach where each tier provides interventions of increasing intensity. RTI has the potential to affect change for English…

  10. Beyond the Laboratory: Evaluating the Survey Evidence for the Disidentification Explanation of Black-White Differences in Achievement.

    ERIC Educational Resources Information Center

    Morgan, Stephen L.; Mehta, Jal D.

    2004-01-01

    The black-white gap in achievement, as measured by performance on standardized tests, has received considerable attention from researchers in the past five years. Claude Steele's stereotype threat and disidentification mechanism is perhaps the most heralded of the new explanations for residual racial differences that persist after adjustments for…

  11. Military Family Coping Project

    DTIC Science & Technology

    2013-09-01

    ORGANIZATION: Baylor University Waco , TX 76798 REPORT DATE: September 2013 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical...ORGANIZATION REPORT NUMBER Waco , TX 76798 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S...CA. Dennis, Regina (Staff Writer). (2012, February 28). Baylor, Waco VA hospital studying veterans’ family stress. Waco , TX: Tribune Herald

  12. Plant Breeding: Surprisingly, Less Sex Is Better.

    PubMed

    van Dijk, Peter J; Rigola, Diana; Schauer, Stephen E

    2016-02-08

    Introduction of apomixis, asexual reproduction through seeds, into crop species has the potential to dramatically transform plant breeding. A new study demonstrates that traits can be stably transferred between generations in newly produced apomictic lines, and heralds a breeding revolution needed to increase food production for the growing planet. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. The shape of the glucose response curve during an oral glucose tolerance test heralds biomarkers of type 2 diabetes risk in obese youth

    USDA-ARS?s Scientific Manuscript database

    The shape of the glucose response curve during an oral glucose tolerance test (OGTT), monophasic versus biphasic, identifies physiologically distinct groups of individuals with differences in insulin secretion and sensitivity. We aimed to verify the value of the OGTT-glucose response curve against m...

  14. A Study of Understanding: Alchemy, Abstraction, and Circulating Reference in Tertiary Science Education

    ERIC Educational Resources Information Center

    Merritt, Brett W.

    2013-01-01

    Understanding is widely touted to be of paramount importance for education. This is especially true in science education research and development where understanding is heralded as one of the cornerstones of reform. Teachers are expected to teach for understanding and students are expected to learn with understanding. This dissertation is an…

  15. Political Ecology in Gabriel Garcia Marquez's "One Hundred Years of Solitude"

    ERIC Educational Resources Information Center

    ElSherief, Eman Mohammed

    2016-01-01

    The roots of ecology prolong profoundly within earlier phases of history, when the naturalistic fabric was first evinced. Bringing out his "On the Origin of Species" in 1859, Darwin not merely engendered a biological culmination but also heralded the revolutionary critical canon of naturalism that was virtually a stone thrown in the vast…

  16. Special forest products: an east-side perspective.

    Treesearch

    William E. Schlosser; Keith A. Blatner

    1997-01-01

    The special forest products industry has gained increasing attention, as timber harvest levels in the Pacific Northwest have declined, and has been heralded, at least by some, as a partial solution to the employment problems common throughout the rural areas of Washington, Oregon, Idaho, and Montana To date, relatively little work has been published on those portions...

  17. Caring for Rosie the Riveter's Children

    ERIC Educational Resources Information Center

    MacKenzie, Bill

    2011-01-01

    During the Second World War, women in the United States who worked in the war industries in such jobs as welders, riveters, heavy machinery operators, and parachute riggers were heralded in the media as "Rosie the Riveter." From 1943 to 1945 a fortunate few of these workplace pioneers participated in a memorable experiment in child care at Kaiser…

  18. Awarding College Credit for MOOCSs: The Role of the American Council on Education

    ERIC Educational Resources Information Center

    Stone, Jason

    2016-01-01

    Emerging alongside the open educational resources movement of the past decade, Massive Open Online Courses (MOOCs) have been widely heralded as advancing cause of providing increased access to higher education. The article explores the implications of the recommendation by the American Council on Education (ACE) to offer college credit for a…

  19. Lifting All Boats? Finance Litigation, Education Resources, and Student Needs in the Post-"Rose" Era

    ERIC Educational Resources Information Center

    Sims, David P.

    2011-01-01

    "Rose v. Council for Better Education" (1989) is often considered a transition point in education finance litigation, heralding an era of increasing concern for measurable adequacy of education across a broad spectrum of student needs. Prior research suggests that post-Rose lawsuits had less effect on the distribution of school spending…

  20. How Social and Critical Constructivism Can Inform Science Curriculum Design: A Study from South Africa

    ERIC Educational Resources Information Center

    Stears, Michele

    2009-01-01

    Background: The introduction of a new National Curriculum in post-apartheid South Africa heralded a different approach in education. This curriculum not only advocated the development of knowledge and skills, but also emphasised education for democracy and citizenship. It seeks to balance central control (and a single curriculum) with local…

  1. Tony Blair, the Promotion of the "Active" Educational Citizen, and Middle-Class Hegemony

    ERIC Educational Resources Information Center

    Reay, Diane

    2008-01-01

    Tony Blair's period as Head of the Labour Government from 1997 until 2007 has been heralded as a period of increased parental power and growing choice within education. However, beneath the rhetoric, Blair's legacy has been one of consolidating and re-inforcing previous Conservative policies that stressed parental responsibilities whilst operating…

  2. When Access for the "Gimme" World Proves Dismissive of Finesse

    ERIC Educational Resources Information Center

    Verdesca, Anthony F., Jr.

    2011-01-01

    A recent "New York Times" article heralded a film documentary whose subject was a competition in which the entrants vied for the title of "one of the best craftsmen of France." The film spotlights the competition between pastry chefs--French pastry chefs--who come from all over France to compete. It's a microcosm of larger…

  3. CHRONIC DEVELOPMENTAL LEAD EXPOSURE REDUCES NEUROGENESIS IN ADULT RAT HIPPOCAMPUS BUT DOES NOT IMPAIR SPATIAL LEARNING.

    EPA Science Inventory

    It has long been heralded that the mature brain does not generate new neurons, it only loses them as a function of injury, disease and age. An exciting recent finding in neuroscience has been that the dentate granule cell layer of the hippocampus has the distinctive property of ...

  4. Crumbling Schools: Tens of Millions Wasted in Slow, Sloppy Construction, and Miami-Dade Children Are the Losers.

    ERIC Educational Resources Information Center

    Cenziper, Debbie; Grotto, Jason

    This series of articles examines the condition of public schools and public school construction in Florida's Miami and Dade Counties. To prepare the series, the Miami Herald studied thousands of pages of construction records, correspondence, school district reports, and accounting statements over 15 years. It analyzed state and national…

  5. New York Newspaper Coverage of Jackie Robinson in His First Major League Season.

    ERIC Educational Resources Information Center

    Washburn, Pat

    Sports articles appearing in three New York City newspapers in Jackie Robinson's first season as a major league baseball player were examined to determine if there was biased reporting based on racial prejudice. The sports pages of the New York "Times," the "Herald Tribune," and the "Daily News" for 44 days in 1947…

  6. Teleworking: Work/Life Balance of Online Instructors with Disabilities: A Phenomenological Study

    ERIC Educational Resources Information Center

    Heisey, Allyson G.

    2012-01-01

    Since the mid-1970s, teleworking has been recognized as being beneficial to organizations, individuals, and communities. In the 1980s and 1990s, advancements in technology made teleworking an attractive option for many workers, including those with disabilities. Teleworking has gained popularity and has been heralded as a method of accommodation…

  7. Conservation and management of Neotropical migrants landbirds in the Northern Rockies and Great Plains [book review

    Treesearch

    Deborah M. Finch

    1995-01-01

    Numerous recent articles and books on the population declines and conservation of neotropical migratory landbirds herald a new interest by university researchers. governmental agencies, and private organizations in inventorying, monitoring, and managing populations of bird species in North America. Dobkin's book, written under contract to the Northern Region of...

  8. Setting Up a Grid-CERT: Experiences of an Academic CSIRT

    ERIC Educational Resources Information Center

    Moller, Klaus

    2007-01-01

    Purpose: Grid computing has often been heralded as the next logical step after the worldwide web. Users of grids can access dynamic resources such as computer storage and use the computing resources of computers under the umbrella of a virtual organisation. Although grid computing is often compared to the worldwide web, it is vastly more complex…

  9. Special Issue: Creating a Tipping Point--Strategic Human Resources in Higher Education

    ERIC Educational Resources Information Center

    Evans, Alvin; Chun, Edna

    2012-01-01

    This monograph examines the emergence of strategic human resource (HR) practices in higher education at a time when the budgetary crisis in public higher education has never been more acute. The wave of financial pressures on public research universities today heralds the advent of an era of unprecedented change. Financial upheaval resulting from…

  10. Teaching Business Statistics in a Computer Lab: Benefit or Distraction?

    ERIC Educational Resources Information Center

    Martin, Linda R.

    2011-01-01

    Teaching in a classroom configured with computers has been heralded as an aid to learning. Students receive the benefits of working with large data sets and real-world problems. However, with the advent of network and wireless connections, students can now use the computer for alternating tasks, such as emailing, web browsing, and social…

  11. Does Knowledge Matter? Disciplinary Identities and Students' Readiness for University

    ERIC Educational Resources Information Center

    McPhail, Graham J.

    2017-01-01

    There is no doubt cultural and technological changes in the late 20th century and beyond have had profound effects on what counts as knowledge and what knowledge counts both at school and at university. This paper considers some implications of a disjuncture identified by Gould ("The New Zealand Herald," 2010) between the curricula and…

  12. Coetzeemyia, a new subgenus of Aedes, and a Redescription of the Holotype Female of Aedes (Coetzeemyia) fryeri (Theobald) (Diptera: Culicidae)

    DTIC Science & Technology

    2010-10-06

    probably constitute an important larval habitat for this species. Females are autogenous in the first ovarian cycle and anautogenous in the second...Amos, D.W. (1944) Mosquito Control Training Manual. Suva, Fiji. Times & Herald. 43 pp. Belkin, J.N. (1962) The mosquitoes of the South Pacific

  13. Promise of new imaging technologies for assessing ovarian function.

    PubMed

    Singh, Jaswant; Adams, Gregg P; Pierson, Roger A

    2003-10-15

    Advancements in imaging technologies over the last two decades have ushered a quiet revolution in research approaches to the study of ovarian structure and function. The most significant changes in our understanding of the ovary have resulted from the use of ultrasonography which has enabled sequential analyses in live animals. Computer-assisted image analysis and mathematical modeling of the dynamic changes within the ovary has permitted exciting new avenues of research with readily quantifiable endpoints. Spectral, color-flow and power Doppler imaging now facilitate physiologic interpretations of vascular dynamics over time. Similarly, magnetic resonance imaging (MRI) is emerging as a research tool in ovarian imaging. New technologies, such as three-dimensional ultrasonography and MRI, ultrasound-based biomicroscopy and synchrotron-based techniques each have the potential to enhance our real-time picture of ovarian function to the near-cellular level. Collectively, information available in ultrasonography, MRI, computer-assisted image analysis and mathematical modeling heralds a new era in our understanding of the basic processes of female and male reproduction.

  14. The benefits of probabilistic exposure assessment: three case studies involving contaminated air, water, and soil.

    PubMed

    Finley, B; Paustenbach, D

    1994-02-01

    Probabilistic risk assessments are enjoying increasing popularity as a tool to characterize the health hazards associated with exposure to chemicals in the environment. Because probabilistic analyses provide much more information to the risk manager than standard "point" risk estimates, this approach has generally been heralded as one which could significantly improve the conduct of health risk assessments. The primary obstacles to replacing point estimates with probabilistic techniques include a general lack of familiarity with the approach and a lack of regulatory policy and guidance. This paper discusses some of the advantages and disadvantages of the point estimate vs. probabilistic approach. Three case studies are presented which contrast and compare the results of each. The first addresses the risks associated with household exposure to volatile chemicals in tapwater. The second evaluates airborne dioxin emissions which can enter the food-chain. The third illustrates how to derive health-based cleanup levels for dioxin in soil. It is shown that, based on the results of Monte Carlo analyses of probability density functions (PDFs), the point estimate approach required by most regulatory agencies will nearly always overpredict the risk for the 95th percentile person by a factor of up to 5. When the assessment requires consideration of 10 or more exposure variables, the point estimate approach will often predict risks representative of the 99.9th percentile person rather than the 50th or 95th percentile person. This paper recommends a number of data distributions for various exposure variables that we believe are now sufficiently well understood to be used with confidence in most exposure assessments. A list of exposure variables that may require additional research before adequate data distributions can be developed are also discussed.

  15. Prodromal Symptoms and Atypical Affectivity as Predictors of Major Depression in Juveniles: Implications for Prevention

    ERIC Educational Resources Information Center

    Kovacs, Maria; Lopez-Duran, Nestor

    2010-01-01

    Background: Given the long-term morbidity of juvenile-onset major depressive disorder (MDD), it is timely to consider whether more effort should be dedicated to its primary and secondary prevention. Methods: We reviewed studies of prodromal symptoms that may herald a first episode pediatric MDD and considered whether that literature has made an…

  16. Education in Northern Ireland since the Good Friday Agreement: Kabuki Theatre Meets "Danse Macabre"

    ERIC Educational Resources Information Center

    Gardner, John

    2016-01-01

    The Good Friday Agreement (1998) between the UK and Irish governments, and most of the political parties in Northern Ireland, heralded a significant step forward in securing peace and stability for this troubled region of the British Isles. From the new-found stability, the previous fits and starts of education reform were replaced by a…

  17. Morse, K. (2003). Does One Size Fit All? Exploring Asynchronous Learning in a Multicultural Environment. "JALN", 7(1), 37-55

    ERIC Educational Resources Information Center

    Zhang, Zuochen

    2004-01-01

    As new technologies become less expensive, provide greater access to various forms of multimedia, and are integrated into all aspects of everyday life, online learning environments are becoming more prevalent. Online education, as experienced through course management systems, is being heralded as meeting the needs of students' lifestyles by…

  18. Recipes for Avoiding Limpness: An Exploration of Women in Senior Management Positions in Australian Universities.

    ERIC Educational Resources Information Center

    Meyenn, Bob; Parker, Judith

    This paper describes a study that explored assumptions regarding the role of women in higher education set forth in the Sydney Morning Herald (Australia) in June 1995 by Dame Leonie Kramer, a prominent academic. She contended that "women go a bit limp when things get tough...." The study was based on semistructured interviews with seven…

  19. Transformation, Trust and the "Importance of Teaching": Continuities and Discontinuities in the Coalition Government's Discourse of Education Reform

    ERIC Educational Resources Information Center

    Bates, Agnieszka

    2012-01-01

    The imperative of transforming education continues to permeate the discourse of UK education reform. Although the Coalition government's publications herald a "new school system", they reveal the same neo-liberal thinking as their New Labour predecessors. The context of the national budget deficit is now being brought to bear to promote…

  20. High-Performance Single-Photon Sources via Spatial Multiplexing

    DTIC Science & Technology

    2014-01-01

    ingredient for tasks such as quantum cryptography , quantum repeater, quantum teleportation, quantum computing, and truly-random number generation. Recently...SECURITY CLASSIFICATION OF: Single photons sources are desired for many potential quantum information applications. One common method to produce...photons sources are desired for many potential quantum information applications. One common method to produce single photons is based on a “heralding

  1. Creating Change? A Review of the Impact of Design and Technology in Schools in England

    ERIC Educational Resources Information Center

    Wilson, Valerie; Harris, Marlene

    2004-01-01

    The role of Design and Technology in schools in England is changing. These changes were heralded by the Government Green Paper "14-19: Extending Opportunities, Raising Standards" (Department for Education and Skills [DfES], 2002), which proposed that education and training of 14-19-year-olds should be delivered by a more flexible…

  2. National League of Cities v. Usery: The Tenth Amendment Is Alive and Doing Well

    ERIC Educational Resources Information Center

    Percy, Billups P.

    1976-01-01

    The Usery decision invalidated an act of Congress as exceeding the commerce power--extension of minimum wage and maximum hour provisions to virtually all employees of states and their political subdivisions. The ruling is a salutary one if it heralds the Supreme Court's recognition that a significant degree of political and economic autonomy for…

  3. 14 CFR 125.509 - Flammability reduction means.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... operational. Table 1 Model—Boeing Model—Airbus 747 Series A318, A319, A320, A321 Series 737 Series A330, A340... comply with § 26.33(c) of this chapter. Table 2 Model—Boeing Model—Airbus 747 Series A318, A319, A320... Herald Type 300. (14) Avions Marcel Dassault—Breguet Aviation Mercure 100C. (15) Airbus Caravelle. (16...

  4. Green Era Should Herald Smarter Buildings

    ERIC Educational Resources Information Center

    Carlson, Scott

    2008-01-01

    In the past two decades, the most elite and ambitious colleges have commissioned buildings by "starchitects" for notoriety. However, people live in a green era now and there is a need for a new kind of star architecture to go with it, one in which the building is a star for its efficiency as well as its elegance. The new star architecture would…

  5. Ionotropic glutamate receptors made crystal clear.

    PubMed

    Bowie, Derek

    2014-12-01

    Two recent crystallographic studies of the full-length GluA2 AMPA receptor provide our first insights into how the modular domains of the tetrameric complex coordinate the process of activation. These findings herald a new era in the structure-function analyses of neurotransmitter receptors, a fitting achievement for the 'International Year of Crystallography'. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. The Impact of a Psychology Learning Community on Academic Success, Retention, and Student Learning Outcomes

    ERIC Educational Resources Information Center

    Buch, Kim; Spaulding, Sue

    2011-01-01

    Learning communities have become an integral part of the educational reform movement of the past two decades and have been heralded as a promising strategy for restructuring undergraduate education. This study used a matched control group design to examine the impact of participation in a psychology learning community (PLC) on a range of student…

  7. Interpreting the Atomic Age: Scientific News Coverage of the Atomic Bomb in Representative Newspapers and Magazines.

    ERIC Educational Resources Information Center

    Barwis, Gail L.

    A study examined the coverage of the scientific aspects of the atomic bomb in four representative newspapers (New York "Times," New York "Herald Tribune," Chicago "Daily Tribune," and Boston "Daily Globe") and in 14 general mass circulation magazines in the time period immediately following the dropping of the bomb. Among the conclusions of the…

  8. The Classroom as Big Sur: Notes on the Liaison Between Evaluation and Professional Growth

    ERIC Educational Resources Information Center

    Sneeden, Ralph

    2013-01-01

    Bill Frisell's new album ("Big Sur") was heralded with a short documentary about its impulse and inception: Frisell's retreat to an isolated coastal ranch in Central California. In the video, he describes the influence of the place, the dramatic and evocative landscape, and how it ultimately became the subject and theme for the…

  9. Exploring the Main Barriers of Technology Integration in the English Language Teaching Classroom: A Qualitative Study

    ERIC Educational Resources Information Center

    Khodabandelou, Rouholllah; That, Junny Ei Mon; Anne A/P S. Selvaraju, Melinda; Ken, Tan Yan; Kewen, Zhu; Yan, Zhang; Ning, Tan Yan

    2016-01-01

    The abundance of technology in recent years has contributed to development in the societies, industries, and education. It is proven from the current trend of technology such as the emergence and rise of smart phones, tablets, laptops and wireless internet connection that the present and future world will be heralded by technology. The integration…

  10. HERALD OF COMMUNICATIONS, 1963. VOL. 23, NO. 1(274).

    DTIC Science & Technology

    enterprises and methods of raising it Green lights for the long distance through calls Organization of delivery service in Voronezh Communication workers ...of Ukrainian SSR can and must work better Production problems are at the center of attention This is the way Soviet communication workers act...Competition for the title ’’Communist-labor main line’’ Literature for communication workers

  11. Breaking the Code: The Creative Use of QR Codes to Market Extension Events

    ERIC Educational Resources Information Center

    Hill, Paul; Mills, Rebecca; Peterson, GaeLynn; Smith, Janet

    2013-01-01

    The use of smartphones has drastically increased in recent years, heralding an explosion in the use of QR codes. The black and white square barcodes that link the physical and digital world are everywhere. These simple codes can provide many opportunities to connect people in the physical world with many of Extension online resources. The…

  12. Global Citizenship and the Role of the United Nations: The Promise of the Early Childhood Peace Consortium

    ERIC Educational Resources Information Center

    Salah, Rima

    2018-01-01

    Today millions of children are trapped in situations of war, conflict, violence and displacement. Science shows that violence has a detrimental effect on the development of young children. It, also, heralds in a new era, with opportunities to contribute to sustaining peace and prevention of violence, through investment in early childhood…

  13. A National Study of Student Early Alert Models at Four-Year Institutions of Higher Education

    ERIC Educational Resources Information Center

    Simons, Jill M.

    2011-01-01

    The purpose of this study was to explore the state of student early alert models at nonprofit, four-year institutions of higher education through both quantitative and qualitative lenses. The use of these retention initiatives has become a much heralded practice on college campuses (Kuh, 2007a; Kuh 2007b; Seidman, 2005; Tinto, 2008). However,…

  14. Effects of Differential Text Formats on Adult Conceptualization of Science: Evidence from Three Disciplines

    ERIC Educational Resources Information Center

    Bird, Nora

    2006-01-01

    The World Wide Web (Web), the largest multimedia system in existence, has been heralded by many as the perfect tool for lifelong learning. One topic mentioned in this regard is science, since many adults have little prior knowledge about it and the field is constantly changing. Yet little empirical research has been done to examine how web…

  15. Citizens Now and for the Future? Leaders, Learners, and 14-19 Reform in England. Messages from Research

    ERIC Educational Resources Information Center

    Morrison, Marlene

    2010-01-01

    How do researchers and practitioners understand and interrogate education reform when it is heralded as the solution to many problems, not all of which are educational? As importantly, how can applied educational researchers delve "beneath the skin" of "given" problems to solve or report, and suggest a range of explanations? In…

  16. Scalable Quantum Networks for Distributed Computing and Sensing

    DTIC Science & Technology

    2016-04-01

    probabilistic measurement , so we developed quantum memories and guided-wave implementations of same, demonstrating controlled delay of a heralded single...Second, fundamental scalability requires a method to synchronize protocols based on quantum measurements , which are inherently probabilistic. To meet...AFRL-AFOSR-UK-TR-2016-0007 Scalable Quantum Networks for Distributed Computing and Sensing Ian Walmsley THE UNIVERSITY OF OXFORD Final Report 04/01

  17. Improving the Health and Well-Being of Adults with Conditions of a Genetic Origin: "Views from Professionals, Syndrome Support Groups and Parents"

    ERIC Educational Resources Information Center

    Redley, Marcus; Pannebakker, Merel; Holland, Anthony

    2018-01-01

    Background: Advances in medical genetics herald the possibility that health and social care services could be more responsive to the needs arising from a person's genotype. This development may be particularly important for those men and women whose learning disability (known internationally as intellectual disability) is linked to a…

  18. Psychological, Philosophical, and Educational Criticisms of Harry Frankfurt's Concept of and Views about "Bullshit" in Human Discourse, Discussions, and Exchanges

    ERIC Educational Resources Information Center

    Perla, Rocco J.; Carifio, James

    2007-01-01

    Princeton University Press recently published the American moral philosopher Harry Frankfurt's book "On Bullshit", which quickly made the New York Times best seller list. Originally published in the journal "Raritan" in 1986, Frankfurt's book has been heralded as an important theoretical development in the study of what he (and society)…

  19. From Performance to Passionate Utterance: Rethinking the Purpose of Restorative Conference Scripts in Schools

    ERIC Educational Resources Information Center

    O'Reilly, Naziya

    2017-01-01

    In recent years restorative practice in schools has been heralded as a new paradigm for thinking about student behaviour. Its premise is to provide solutions to indiscipline, to restore relationships where there has been conflict or harm, and to give pupils a language with which to understand wrongdoing. This article offers a critique of…

  20. Dominican Republic: Political and Economic Conditions and Relations with the United States

    DTIC Science & Technology

    2005-03-08

    Killed in Dominican Republic Prison Fire,” The New York Times, March 8, 2008. 8 See Gerardo Reyes, “Esclavos en Paraíso,”El Nuevo Herald, Jan. 9... Perez , “Widespread Blackouts Leave President Scrambling to Boost Power,” Agence France-Presse, Feb. 8, 2000. 13 Jose de Cordoba, “Caribbean Cloud,”Wall

  1. Students At-Risk: Poverty, Pregnancy, Violence, Depression, and the Demise of the Traditional Family. Second Edition.

    ERIC Educational Resources Information Center

    Bonilla, Carlos A., Ed.; Goss, Joyce, Ed.; Lauderdale, Katherine Lynn, Ed.

    This book was designed by a group of teachers and would-be teachers to let their voices be heard, their concerns aired, their suggestions heralded, and their ideas concerning students at risk be proclaimed. The following articles are presented: (1) "Children in Poverty" (Cris Fruzza, Carlos A. Bonilla, Katherine L. Lauderdale, Eric Affleck); (2)…

  2. Politics of Policy: Assessing the Implementation, Impact, and Evolution of the Performance Assessment for California Teachers (PACT) and edTPA

    ERIC Educational Resources Information Center

    Reagan, Emilie Mitescu; Schram, Thomas; McCurdy, Kathryn; Chang, Te-Hsin; Evans, Carla M.

    2016-01-01

    Summative performance assessments in teacher education, such as the Performance Assessment for California Teachers (PACT) and the edTPA, have been heralded through polices intended to enhance the quality of the teaching profession and raise its stature among other professions. However, the development and implementation of the PACT, and…

  3. The Intellectual Climate of the Late Nineteenth Century and the Fate of American Normal Schools

    ERIC Educational Resources Information Center

    Diener, David

    2008-01-01

    In 1839 the first normal school in the United States opened in Lexington, Massachusetts. Heralded as "an instrument of great good" (Everett 1863, 769) and a spring in which was coiled "a vigor whose uncoiling may wheel the spheres" (Ogren 2005, 16), normal schools continued to grow in numbers throughout the nineteenth century and produced…

  4. Designing an Intervention to Promote Critical Thinking about Statistics in the General Public

    ERIC Educational Resources Information Center

    Velautham, Leela

    2017-01-01

    "One in five American households do not have a single member in the labor force." This was a statistic heralded by President-elect Donald Trump (Appelbaum, 2016, para. 2), in a speech during the election campaign, to illustrate the apparently huge number of unemployed Americans and, thus, to expose the perilous state of the American…

  5. Heralded high-efficiency quantum repeater with atomic ensembles assisted by faithful single-photon transmission

    NASA Astrophysics Data System (ADS)

    Li, Tao; Deng, Fu-Guo

    2015-10-01

    Quantum repeater is one of the important building blocks for long distance quantum communication network. The previous quantum repeaters based on atomic ensembles and linear optical elements can only be performed with a maximal success probability of 1/2 during the entanglement creation and entanglement swapping procedures. Meanwhile, the polarization noise during the entanglement distribution process is harmful to the entangled channel created. Here we introduce a general interface between a polarized photon and an atomic ensemble trapped in a single-sided optical cavity, and with which we propose a high-efficiency quantum repeater protocol in which the robust entanglement distribution is accomplished by the stable spatial-temporal entanglement and it can in principle create the deterministic entanglement between neighboring atomic ensembles in a heralded way as a result of cavity quantum electrodynamics. Meanwhile, the simplified parity-check gate makes the entanglement swapping be completed with unity efficiency, other than 1/2 with linear optics. We detail the performance of our protocol with current experimental parameters and show its robustness to the imperfections, i.e., detuning and coupling variation, involved in the reflection process. These good features make it a useful building block in long distance quantum communication.

  6. Towards a heralded eigenstate-preserving measurement of multi-qubit parity in circuit QED

    NASA Astrophysics Data System (ADS)

    Huembeli, Patrick; Nigg, Simon E.

    2017-07-01

    Eigenstate-preserving multi-qubit parity measurements lie at the heart of stabilizer quantum error correction, which is a promising approach to mitigate the problem of decoherence in quantum computers. In this work we explore a high-fidelity, eigenstate-preserving parity readout for superconducting qubits dispersively coupled to a microwave resonator, where the parity bit is encoded in the amplitude of a coherent state of the resonator. Detecting photons emitted by the resonator via a current biased Josephson junction yields information about the parity bit. We analyze theoretically the measurement back action in the limit of a strongly coupled fast detector and show that in general such a parity measurement, while approximately quantum nondemolition is not eigenstate preserving. To remediate this shortcoming we propose a simple dynamical decoupling technique during photon detection, which greatly reduces decoherence within a given parity subspace. Furthermore, by applying a sequence of fast displacement operations interleaved with the dynamical decoupling pulses, the natural bias of this binary detector can be efficiently suppressed. Finally, we introduce the concept of a heralded parity measurement, where a detector click guarantees successful multi-qubit parity detection even for finite detection efficiency.

  7. Heralded high-efficiency quantum repeater with atomic ensembles assisted by faithful single-photon transmission.

    PubMed

    Li, Tao; Deng, Fu-Guo

    2015-10-27

    Quantum repeater is one of the important building blocks for long distance quantum communication network. The previous quantum repeaters based on atomic ensembles and linear optical elements can only be performed with a maximal success probability of 1/2 during the entanglement creation and entanglement swapping procedures. Meanwhile, the polarization noise during the entanglement distribution process is harmful to the entangled channel created. Here we introduce a general interface between a polarized photon and an atomic ensemble trapped in a single-sided optical cavity, and with which we propose a high-efficiency quantum repeater protocol in which the robust entanglement distribution is accomplished by the stable spatial-temporal entanglement and it can in principle create the deterministic entanglement between neighboring atomic ensembles in a heralded way as a result of cavity quantum electrodynamics. Meanwhile, the simplified parity-check gate makes the entanglement swapping be completed with unity efficiency, other than 1/2 with linear optics. We detail the performance of our protocol with current experimental parameters and show its robustness to the imperfections, i.e., detuning and coupling variation, involved in the reflection process. These good features make it a useful building block in long distance quantum communication.

  8. Heralded high-efficiency quantum repeater with atomic ensembles assisted by faithful single-photon transmission

    PubMed Central

    Li, Tao; Deng, Fu-Guo

    2015-01-01

    Quantum repeater is one of the important building blocks for long distance quantum communication network. The previous quantum repeaters based on atomic ensembles and linear optical elements can only be performed with a maximal success probability of 1/2 during the entanglement creation and entanglement swapping procedures. Meanwhile, the polarization noise during the entanglement distribution process is harmful to the entangled channel created. Here we introduce a general interface between a polarized photon and an atomic ensemble trapped in a single-sided optical cavity, and with which we propose a high-efficiency quantum repeater protocol in which the robust entanglement distribution is accomplished by the stable spatial-temporal entanglement and it can in principle create the deterministic entanglement between neighboring atomic ensembles in a heralded way as a result of cavity quantum electrodynamics. Meanwhile, the simplified parity-check gate makes the entanglement swapping be completed with unity efficiency, other than 1/2 with linear optics. We detail the performance of our protocol with current experimental parameters and show its robustness to the imperfections, i.e., detuning and coupling variation, involved in the reflection process. These good features make it a useful building block in long distance quantum communication. PMID:26502993

  9. "You Have to Be Involved...to Play a Part in It": Assessing Kainai Attitudes about Voting in Canadian Elections

    ERIC Educational Resources Information Center

    Belanger, Yale D.

    2009-01-01

    Two days prior to the federal election on June 28, 2004, the "Lethbridge Herald" ran an article in which the renowned Cree leader and former Member of Parliament Elijah Harper (Churchill electoral district in Manitoba, 1993-97) publicly implored First Nations people in Canada to participate in the forthcoming vote. Citing the recent…

  10. Implementing the Opening Minds Curriculum in a Secondary School in England: An Alternative to the One-Size-Fits-All National Curriculum?

    ERIC Educational Resources Information Center

    Stanley, Grant; Jones, Marion; Murphy, Jan

    2012-01-01

    "The Importance of Teaching: The Schools White Paper 2010," which grants schools increased autonomy in curriculum development and implementation, heralded a new era of curriculum reform in England. This article critically examines how this process took place in a Catholic secondary school that decided to use the RSA Opening Minds (OM)…

  11. Managing Perception: A Twenty-First Century Imperative

    DTIC Science & Technology

    2006-02-13

    computer users not logged on, insurgents have distributed CDs and DVDs. This material, enhanced with video , soundtracks, and professional editing...news, and bloggers, and e-mails, and digital cameras, and Sony video cams, and all of these things that bring so much information near instantaneously...December 2005. 10 Lolita C. Baldor, Associated Press, “Pentagon Describes Iraq Propaganda Plan,” Miami Herald, 4 December 2005, [article on-line

  12. The beginnings of life as a cosmic phenomenon

    NASA Astrophysics Data System (ADS)

    Wickramasinghe, N. C.

    2015-09-01

    The emerging consensus that comets carry the biochemical seeds of life coincides with the first step that was reached as early as 1977 in the historical development of the Hoyle-Wickramasinghe theory of cosmic life. To mark the centenary of the birth of Sir Fred Hoyle on 24 June 2015 this brief article retraces early developments that essentially heralded the new science of astrobiology.

  13. Phenobarbital-responsive episodic dyscontrol (rage) in dogs.

    PubMed

    Dodman, N H; Miczek, K A; Knowles, K; Thalhammer, J G; Shuster, L

    1992-11-15

    Episodic dyscontrol (rage) was diagnosed from the clinical history, electroencephalographic findings, and response to oral treatment with phenobarbital in 3 dogs. Clinical features included a mood change heralding aggressive incidents, explosive aggression directed at people or objects, and a postaggressive phase characterized by lethargy and lack of responsiveness. Abnormal electroencephalographic findings included spike activity in the temporal recordings. All 3 dogs responded well to anticonvulsant medication with phenobarbital.

  14. The Militarization of the Prairie: Scrap Drives, Metaphors, and the "Omaha World-Herald's" 1942 "Nebraska Plan"

    ERIC Educational Resources Information Center

    Kimble, James J.

    2007-01-01

    In WW II, there was no nationwide shortage of scrap on the home front. In backyards, attics, barns, ditches, garages, and factory storage sheds across the country, all sorts of scrap material awaited transport and eventual conversion to arms. Yet the public's awareness of the scrap, and the national willpower necessary to collect it, seemed to be…

  15. Star of Bethlehem

    NASA Astrophysics Data System (ADS)

    Hughes, D.; Murdin, P.

    2001-07-01

    The biblical Star of Bethlehem, which heralded the birth of Jesus Christ, is only mentioned in the Gospel of St Matthew 2. The astrologically significant 7 bc triple conjunction of Jupiter and Saturn in the constellation of Pisces is the most likely candidate, although a comet/nova in 5 bc and a comet in 4 bc cannot be ruled out. There is also the possibility that the star was simply fictitious....

  16. A Collision of Vice and Virtue in Thomas Hardy's Tess of the D'Urbervilles: "A Pure Woman Faithfully Presented" or a Fallen Angel

    ERIC Educational Resources Information Center

    Saleh, Nafiseh Salman; Abbasi, Pyeaam

    2014-01-01

    Heralded as a sympathizer with the oppressed nineteenth century femininity, Thomas Hardy adopted an aggressive stance towards the institutionalized codes of the time, particularly the ideal of femininity which results in presenting him as one of the promethean forerunners of "New Woman" fiction. His outspoken attitudes are tangible in…

  17. Military Family Coping Project - Phase 2

    DTIC Science & Technology

    2014-09-01

    ORGANIZATION: Baylor University, Waco , TX 76798 REPORT DATE: September 2014 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical Research and...February 28). Baylor, Waco VA hospital studying veterans’ family stress. Waco , TX: Tribune Herald. Slayden, Stacey (Reporter). (2012, February 28...VA Hospital and Baylor University team up to study effects of deployment. Waco , TX: Fox 44 news. Ellor, J. W., Crow, J, Myers, D., Morissette, S

  18. Disruptor, Distracter, or What? A Policymaker's Guide to Massive Open Online Courses (MOOCs)

    ERIC Educational Resources Information Center

    Kelly, Andrew P.

    2014-01-01

    The creation of the massive open online course (MOOC), a new form of digital learning, has enthralled some, infuriated others, and changed the conversation about higher education in the United States and abroad. To some, MOOCs herald the dawn of a new era in human capital, one that will mean the end of college as we know it. Enthusiastic observers…

  19. The "Youngest" Illinoisans: A Statistical Look at Infants and Toddlers in Illinois. Publication #2013-53

    ERIC Educational Resources Information Center

    Murphey, David; Cooper, Mae; Forry, Nicole

    2014-01-01

    Illinois' youngest children--nearly half-a-million infants and toddlers--are at the leading edge of a demographic transformation. They herald a state, and a nation, more diverse with respect to race/ethnicity, country of origin, language, and family type than at any time in recent history. Yet, this is a generation notable for marked inequities,…

  20. "I DON'T CARE DO UR OWN PAGE!!" A Case Study of Using Wikis for Collaborative Work in a UK Secondary School

    ERIC Educational Resources Information Center

    Grant, Lyndsay

    2009-01-01

    Alongside other forms of social software, wikis have been heralded as supporting more collaborative and democratic teaching and learning practices. This paper explores, through a case study approach, the use of wikis to support a collaborative research project undertaken in a UK secondary school. Findings are analysed in the context of research on…

  1. A Smart Social Inclusion Policy for the EU: The Role of Education and Training

    ERIC Educational Resources Information Center

    Nicaise, Ides

    2012-01-01

    Whereas in 2000 the EU had heralded the knowledge-based society with as its motto "with more and better jobs and stronger social cohesion", the past decade has led to greater inequality and (at best) a status-quo in poverty. EU2020 seems to acknowledge this failure and aims to reconnect social inclusion with the knowledge-based strategy.…

  2. Military Herald Indices (1975-1979). Volume 1.

    DTIC Science & Technology

    1988-11-01

    Volume I Allan S . Rehm Lauren Van Metre Charles B. Hall DTICELECTE ________ § 12 19890 A Division of Hudson Institute CENTER FOR NAVAL ANALYSES 4401...DECLASSIFICATIONDOWNGRADING SCApproved for Public Release; Distribution Unlimited 4. PERFORMING ORGANIZATION REPORT NUMBER( S ) 5. MONITORING ORGANIZATION REPORT NUMBER( S ...Virginia 22302-0268 Washington, D.C. 20350-1000 S &. NAME OF FUNDING ORGANIZATION 8b. OFFICE SYMBOL 9. PROCUREMENT INSTRUMENT IDENTIFICATION NUMBER

  3. Southeast Asia Report

    DTIC Science & Technology

    1984-12-14

    Reception Held (KPL, 23 Nov 84)..U...................... 33 Briefs ............. Delegation to USSR ’ 34 GDR Trade Union Delegation 34...THE EVENING POST, 17 Oct 84) 56 Transnational Union Head Rejects ANZUS (THE NEW ZEALAND HERALD, 17 Oct 84) °’ Daily Welcomes ’Favorable...overall supply and demand , the Australian Wool Cor- poration bought 211,000 bales in the first quarter of the season. Corporation stocks were now 1.5

  4. The Most Important Events of 1981 as Seen by Reporters, Editors, Wire Services and Media Consumers.

    ERIC Educational Resources Information Center

    Ogan, Christine L.; Lafky, Sue A.

    Bloomington, Indiana citizens and 19 members of the editorial staff of the "Herald-Telephone" were surveyed to determine whether the audience for news had the same notion of news value as those who decide what news will be available on any given day. The respondents were asked to list the events most important to them in 1981, on the…

  5. Realizing Kentucky's Educational Attainment Goal: A Look in the Rear View Mirror and down the Road Ahead

    ERIC Educational Resources Information Center

    Kelly, Patrick J.

    2011-01-01

    In 1997, policymakers in Kentucky enacted perhaps the most sweeping higher education reform legislation of any state in the past two decades. Kentucky's Postsecondary Education Improvement Act (House Bill 1) has been heralded by many higher education leaders across the U.S. as one of the great success stories--a rare instance when a state's…

  6. Transitory Connections: The Reception and Rejection of Jean Piaget's Psychology in the Nursery School Movement in the 1920s and 1930s

    ERIC Educational Resources Information Center

    Beatty, Barbara

    2009-01-01

    In 1927, nursery school educator Lucy Sprague Mitchell heralded Jean Piaget's psychology as of "outstanding interest" and wrote in "Progressive Education" that it should be of "immense service" to psychologists, teachers, and parents. In 1929, psychologist Lois Meek praised Piaget's research in the National Society for the Study of Education's…

  7. Korean Affairs Report

    DTIC Science & Technology

    1986-02-18

    cooperation among themselves and to give top priority to preparing for the Asian Games . The president directed the sports minister to complete construction at...should conduct a nationwide campaign to promote public order, kindness and cleanliness. Chon also asked the sports minister to boost the competitive ...Jan 86) 4 Daily Views Soviet Foreign Minister’s Visit to North (Editorial; THE KOREA HERALD, 25 Jan 86) 5 OLYMPIC GAMES State Advisors

  8. Facing the Urban Challenge: Reimagining Land Use in America's Distressed Older Cities--The Federal Policy Role

    ERIC Educational Resources Information Center

    Mallach, Alan

    2010-01-01

    The end of World War II heralded an era of urban disinvestment in the United States. While some cities began to rebound in the 1990s with population and economic growth, others--including large cities like Detroit, Cleveland, and St. Louis as well as many smaller cities and towns--did not, and have continued to decline. As these communities…

  9. Passing the Torch: Does Higher Education for the Disadvantaged Pay Off across the Generations? American Sociological Association's Rose Series in Sociology

    ERIC Educational Resources Information Center

    Attewell, Paul; Lavin, David; Domina, Thurston; Levey, Tania

    2009-01-01

    The steady expansion of college enrollment rates over the last generation has been heralded as a major step toward reducing chronic economic disparities. But many of the policies that broadened access to higher education--including affirmative action, open admissions, and need-based financial aid--have come under attack in recent years by critics…

  10. Southeast Asia Report.

    DTIC Science & Technology

    1984-10-11

    Unfamiliar names rendered phonetically or transliterated are enclosed in parentheses. Words or names preceded by a ques- tion mark and enclosed in...48 Batasan Examines Volume, Inconsistency of Marcos Decrees (Mariano M . Florido; VISAYAN HERALD, 10 Sep 84) 52 KBL Leaders Consider ’Political...QIIAN ÜOI NHAN DAN, Jul 84) M Artillery Mobility Requirements Outlined (Nguyen Dinh Thach; TAP CHI QUAN DOI NHAN DAN, Jul 84) 101 PARTY

  11. Protecting Diplomats in Iraq: What Can the U.S. Department of State do to Improve it’s Management and Oversight of Security Contractors in Iraq

    DTIC Science & Technology

    2008-01-01

    2004 Mission." Associated Press Financial Wire, October 24,2007, sec. Business News. http://proquest.com. Lee , Mattew. "Rice: New State Dept. Security...Front Page. http://proquest.com. Strobel , Warren P. "Iraq Panel Charges Feds Interference." Monterey County Herald, September 26,2007, sec. National. http

  12. Geology and physiography of the continental margin north of Alaska and implications for the origin of the Canada Basin

    USGS Publications Warehouse

    Grantz, Arthur; Eittreim, Stephen L.; Whitney, O.T.

    1979-01-01

    The continental margin north of Alaska is of Atlantic type. It began to form probably in Early Jurassic time but possibly in middle Early Cretaceous time, when the oceanic Canada Basin of the Arctic Ocean is thought to have opened by rifting about a pole of rotation near the Mackenzie Delta. Offsets of the rift along two fracture zones are thought to have divided the Alaskan margin into three sectors of contrasting structure and stratigraphy. In the Barter Island sector on the east and the Chukchi sector on the west the rift was closer to the present northern Alaska mainland than in the Barrow sector, which lies between them. In the Barter Island and Chukchi sectors the continental shelf is underlain by prisms of clastic sedimentary rocks that are inferred to include thick sections of Jurassic and Neocomian (lower Lower Cretaceous) strata of southern provenance. In the intervening Barrow sector the shelf is underlain by relatively thin sections of Jurassic and Neocomian strata derived from northern sources that now lie beneath the outer continental shelf. The rifted continental margin is overlain by a prograded prism of Albian (upper Lower Cretaceous) to Tertiary clastic sedimentary rocks that comprises the continental terrace of the western Beaufort and northern Chukchi Seas. On the south the prism is bounded by Barrow arch, which is a hingeline between the northward-tilted basement surface beneath the continental shelf of the western Beaufort Sea and the southward-tilted Arctic Platform of northern Alaska. The Arctic platform is overlain by shelf clastic and carbonate strata of Mississippian to Cretaceous age, and by Jurassic and Cretaceous clastic strata of the Colville foredeep. Both the Arctic platform and Colville foredeep sequences extend from northern Alaska beneath the northern Chukchi Sea. At Herald fault zone in the central Chukchi Sea they are overthrust by more strongly deformed Cretaceous to Paleozoic sedimentary rocks of Herald arch, which trends northwest from Cape Lisburne. Hope basin, an extensional intracontinental sedimentary basin of Tertiary age, underlies the Chukchi Sea south of Herald arch.

  13. Using the EUV to Weigh a Sun-Grazing Comet as it Disappears in the Solar Corona

    NASA Technical Reports Server (NTRS)

    Pesnell, William Dean; Schrijiver, Carolus J.; Brown, John C.; Battams, Karl; Saint-Hilaire, Pascal; Hudson Hugh S.; Lui, Wei

    2012-01-01

    On July 6,2011, the Atmospheric Imaging Assembly (AlA) on the Solar Dynamics Observatory (SDO) observed a comet in most of its EUY passbands. The comet disappeared while moving through the solar corona. The comet penetrated to 0.146 solar radii ($\\simapprox.100,000 km) above the photosphere before its EUY faded. Before then, the comet's coma and a tail were observed in absorption and emission, respectively. The material in the variable tail quickly fell behind the nucleus. An estimate of the comet's mass based on this effect, one derived from insolation, and one using the tail's EUY brightness, all yield $\\sim 50$ giga-grams some 10 minutes prior to the end of its visibility. These unique first observations herald a new era in the study of Sun-grazing comets close to their perihelia and of the conditions in the solar corona and solar wind. We will discuss the observations and interpretation of the comet by SDO as well as the coronagraph observations from SOHO and STEREO. A search of the SOHO comet archive for other comets that could be observed in the SDO; AlA EUY channels will be described

  14. Identification of nonclassical properties of light with multiplexing layouts

    NASA Astrophysics Data System (ADS)

    Sperling, J.; Eckstein, A.; Clements, W. R.; Moore, M.; Renema, J. J.; Kolthammer, W. S.; Nam, S. W.; Lita, A.; Gerrits, T.; Walmsley, I. A.; Agarwal, G. S.; Vogel, W.

    2017-07-01

    In Sperling et al. [Phys. Rev. Lett. 118, 163602 (2017), 10.1103/PhysRevLett.118.163602], we introduced and applied a detector-independent method to uncover nonclassicality. Here, we extend those techniques and give more details on the performed analysis. We derive a general theory of the positive-operator-valued measure that describes multiplexing layouts with arbitrary detectors. From the resulting quantum version of a multinomial statistics, we infer nonclassicality probes based on a matrix of normally ordered moments. We discuss these criteria and apply the theory to our data which are measured with superconducting transition-edge sensors. Our experiment produces heralded multiphoton states from a parametric down-conversion light source. We show that the known notions of sub-Poisson and sub-binomial light can be deduced from our general approach, and we establish the concept of sub-multinomial light, which is shown to outperform the former two concepts of nonclassicality for our data.

  15. Identification of nonclassical properties of light with multiplexing layouts

    PubMed Central

    Sperling, J.; Eckstein, A.; Clements, W. R.; Moore, M.; Renema, J. J.; Kolthammer, W. S.; Nam, S. W.; Lita, A.; Gerrits, T.; Walmsley, I. A.; Agarwal, G. S.; Vogel, W.

    2018-01-01

    In Sperling et al. [Phys. Rev. Lett. 118, 163602 (2017)], we introduced and applied a detector-independent method to uncover nonclassicality. Here, we extend those techniques and give more details on the performed analysis. We derive a general theory of the positive-operator-valued measure that describes multiplexing layouts with arbitrary detectors. From the resulting quantum version of a multinomial statistics, we infer nonclassicality probes based on a matrix of normally ordered moments. We discuss these criteria and apply the theory to our data which are measured with superconducting transition-edge sensors. Our experiment produces heralded multiphoton states from a parametric down-conversion light source. We show that the known notions of sub-Poisson and sub-binomial light can be deduced from our general approach, and we establish the concept of sub-multinomial light, which is shown to outperform the former two concepts of nonclassicality for our data. PMID:29670949

  16. Towards Mutuality in the Canada-China Relationship: The Experience of the Department of Surgery at Laval University since the 1980s

    ERIC Educational Resources Information Center

    Guidoin, Robert; Wang, Lu; Douville, Yvan

    2015-01-01

    The Department of Surgery at Laval University has been a key player in the development of Canada-China cooperation since the 1980s. The projects initiated and developed by Jean Couture and Guojin Liu to address cancer issues, and specifically breast cancer, were heralded as outstanding successes. In the meantime, the Department of Surgery at Laval…

  17. Hark the Herald Tables Sing! Achieving Higher-Order Thinking with a Chorus of Sixth-Form Pupils

    ERIC Educational Resources Information Center

    Orth, Simon; Lacey, Daniel; Smith, Neil

    2015-01-01

    On 9 April 1930, a philanthropist called Edward Harkness donated millions of dollars to the Phillips Exeter Academy in the USA. He hoped that his donation could be used to find a new way for students to sit around a table with their teacher and "feel encouraged to speak up". This led to the development of what is now known as the…

  18. "Smart Students Get Perfect Scores in Tests without Studying Much": Why Is an Effortless Achiever Identity Attractive, and for Whom Is It Possible?

    ERIC Educational Resources Information Center

    Jackson, Carolyn; Nyström, Anne-Sofie

    2015-01-01

    Discourses about the value of effort and hard work are prevalent and powerful in many western societies and educational contexts. Yet, paradoxically, in these same contexts effortless achievement is often lauded, and in certain discourses is heralded as the pinnacle of success and a sign of genius. In this paper we interrogate discourses about…

  19. Sub-Saharan African Report, No. 2806

    DTIC Science & Technology

    1983-06-06

    Telmo de Almeida, officials from the State Secretariat for Cooperation, and other eminent persons . 9805 CSO: 3442/211 ANGOLA IMPASSE ON...ETHIOPIAN HERALD in English 21 Apr 83 p 2 [ Article by Wolde Michael H. Mariam] [Text] The Agricultural and Industrial Development Bank (AIDB) is a... Article by Arefayne Hagos] [Text] The Simien Mountains National Park, one of the richest natural sites in the world, rests on 225 square kilometers in

  20. A Fabric Revolution. AFFOA Is Weaving the Next Fiber and Textile Revolution

    DTIC Science & Technology

    2016-10-01

    adapt to both hot and cold environments • Home insulation and road construction materials that can monitor the performance of insulation and water...hear, sense, communicate, store and convert energy, regulate temperature, monitor health and change color—heralding the dawn of a “fabric...environ- mental conditions or wearer needs, monitoring health factors to both sense and treat injury, generating and/or storing energy from the

  1. Atom Interferometry on Atom Chips - A Novel Approach Towards Precision Inertial Navigation System - PINS

    DTIC Science & Technology

    2010-06-01

    Demonstration of an area-enclosing guided-atom interferometer for rotation sensing, Phys. Rev. Lett. 99, 173201 (2007). 4. Heralded Single- Magnon Quantum...excitations are quantized spin waves ( magnons ), such that transitions between its energy levels ( magnon number states) correspond to highly directional...polarization storage in the form of a single collective-spin excitation ( magnon ) that is shared between two spatially overlapped atomic ensembles

  2. Iran and Latin America: Strategic Security Issues

    DTIC Science & Technology

    2011-05-01

    written extensively on asymmetrical warfare. known as Carlos the Jackal )3 for helping to expand the parameters of what irregular warfare should...international furor. See: "Troops Get Provocative Book," Miami Herald, Nov. II, 2005. 4 Ian James, "Chavez Praises Carlos the Jackal ," Associated Press...November 21, 2009, accessed January 24, 20 II, at: http:/ /www.independent.co. uk!news/world/americas/chavez-praises-carlos-the- jackal - 1825135.html

  3. Towards a unification of evolutionary dynamics. Comment on "Answering Schrödinger's question: A free-energy formulation" by Maxwell James Désormeau Ramstead et al.

    NASA Astrophysics Data System (ADS)

    Campbell, John O.

    2018-03-01

    In 2006 Karl Friston introduced the free energy principle (FEP) to neuroscience as a unifying concept [1]. This proposal, along with its use in developing the 'Bayesian Brain' formulation quickly gained traction and a 2008 feature article in New Scientist heralded it as providing a promising unified theory of the brain [2]:

  4. Compact Single Site Resolution Cold Atom Experiment for Adiabatic Quantum Computing

    DTIC Science & Technology

    2016-02-03

    goal of our scientific investigation is to demonstrate high fidelity and fast atom-atom entanglement between physically 1. REPORT DATE (DD-MM-YYYY) 4...of our scientific investigation is to demonstrate high fidelity and fast atom-atom entanglement between physically separated and optically addressed...Specifically, we will design and construct a set of compact single atom traps with integrated optics, suitable for heralded entanglement and loophole

  5. Translations on Sub-Saharan Africa, No. 2023.

    DTIC Science & Technology

    1978-11-15

    1, 3 Nov 78) 134 Half of Country Affected Bishop Expresses Fears Warning on Martial Law Extension Offered (Editorial; THE HERALD, 2 Nov 78...water level will be seriously affected . Unless the development of the Senegal River Basin is highly co-ordinated in the future, success will be a long...population will be affected anyway. National administrations are already moving into the area, notably SAEü’of Senegal, whose authority spreads along

  6. Linguistic Extensions of Topic Models

    DTIC Science & Technology

    2010-09-01

    Movie Legally Multiplex Heralded As Linchpin To Growth The Shape of Cinema , Transformed At the Click of a Mouse A Peaceful Crew Puts Muppets...Linguistic Representation of Multiple Languages The formalism of WordNet has been applied to many languages from different language families, e.g. Japanese ...could be also share information gleaned from 100 reviews on Amazon.com’s Japanese and German language sites. 6.2.3 Learning Deeper Structures and Testing

  7. The role of trust in residents’ fire wise actions

    Treesearch

    Jim Absher; Jerry J. Vaske

    2011-01-01

    Residents’ trust in the managing agency has been heralded as a necessary precursor to success in preventing wildland fire losses in the wildland–urban interface. Trust, however, is a complex concept. Homeowners’ specific fire wise actions may not be easily linked to general measures of trust. This article uses two distinct trust indices to predict residents’ intention...

  8. Circulating tumor DNA: a promising biomarker in the liquid biopsy of cancer.

    PubMed

    Cheng, Feifei; Su, Li; Qian, Cheng

    2016-07-26

    Tissue biopsy is the standard diagnostic procedure for cancers and also provides a material for genotyping, which can assist in the targeted therapies of cancers. However, tissue biopsy-based cancer diagnostic procedures have limitations in their assessment of cancer development, prognosis and genotyping, due to tumor heterogeneity and evolution. Circulating tumor DNA (ctDNA) is single- or double-stranded DNA released by the tumor cells into the blood and it thus harbors the mutations of the original tumor. In recent years, liquid biopsy based on ctDNA analysis has shed a new light on the molecular diagnosis and monitoring of cancer. Studies found that the screening of genetic mutations using ctDNA is highly sensitive and specific, suggesting that ctDNA analysis may significantly improve current systems of tumor diagnosis, even facilitating early-stage detection. Moreover, ctDNA analysis is capable of accurately determining the tumor progression, prognosis and assisting in targeted therapy. Therefore, using ctDNA as a liquid biopsy may herald a revolution for tumor management. Herein, we review the biology of ctDNA, its detection methods and potential applications in tumor diagnosis, treatment and prognosis.

  9. Circulating tumor DNA: a promising biomarker in the liquid biopsy of cancer

    PubMed Central

    Cheng, Feifei; Su, Li; Qian, Cheng

    2016-01-01

    Tissue biopsy is the standard diagnostic procedure for cancers and also provides a material for genotyping, which can assist in the targeted therapies of cancers. However, tissue biopsy-based cancer diagnostic procedures have limitations in their assessment of cancer development, prognosis and genotyping, due to tumor heterogeneity and evolution. Circulating tumor DNA (ctDNA) is single- or double-stranded DNA released by the tumor cells into the blood and it thus harbors the mutations of the original tumor. In recent years, liquid biopsy based on ctDNA analysis has shed a new light on the molecular diagnosis and monitoring of cancer. Studies found that the screening of genetic mutations using ctDNA is highly sensitive and specific, suggesting that ctDNA analysis may significantly improve current systems of tumor diagnosis, even facilitating early-stage detection. Moreover, ctDNA analysis is capable of accurately determining the tumor progression, prognosis and assisting in targeted therapy. Therefore, using ctDNA as a liquid biopsy may herald a revolution for tumor management. Herein, we review the biology of ctDNA, its detection methods and potential applications in tumor diagnosis, treatment and prognosis. PMID:27223063

  10. Heralded entanglement between solid-state qubits separated by three metres.

    PubMed

    Bernien, H; Hensen, B; Pfaff, W; Koolstra, G; Blok, M S; Robledo, L; Taminiau, T H; Markham, M; Twitchen, D J; Childress, L; Hanson, R

    2013-05-02

    Quantum entanglement between spatially separated objects is one of the most intriguing phenomena in physics. The outcomes of independent measurements on entangled objects show correlations that cannot be explained by classical physics. As well as being of fundamental interest, entanglement is a unique resource for quantum information processing and communication. Entangled quantum bits (qubits) can be used to share private information or implement quantum logical gates. Such capabilities are particularly useful when the entangled qubits are spatially separated, providing the opportunity to create highly connected quantum networks or extend quantum cryptography to long distances. Here we report entanglement of two electron spin qubits in diamond with a spatial separation of three metres. We establish this entanglement using a robust protocol based on creation of spin-photon entanglement at each location and a subsequent joint measurement of the photons. Detection of the photons heralds the projection of the spin qubits onto an entangled state. We verify the resulting non-local quantum correlations by performing single-shot readout on the qubits in different bases. The long-distance entanglement reported here can be combined with recently achieved initialization, readout and entanglement operations on local long-lived nuclear spin registers, paving the way for deterministic long-distance teleportation, quantum repeaters and extended quantum networks.

  11. Monitoring crater-wall collapse at active volcanoes: a study of the 12 January 2013 event at Stromboli

    NASA Astrophysics Data System (ADS)

    Calvari, Sonia; Intrieri, Emanuele; Di Traglia, Federico; Bonaccorso, Alessandro; Casagli, Nicola; Cristaldi, Antonio

    2016-05-01

    Crater-wall collapses are fairly frequent at active volcanoes and they are normally studied through the analysis of their deposits. In this paper, we present an analysis of the 12 January 2013 crater-wall collapse occurring at Stromboli volcano, investigated by means of a monitoring network comprising visible and infrared webcams and a Ground-Based Interferometric Synthetic Aperture Radar. The network revealed the triggering mechanisms of the collapse, which are comparable to the events that heralded the previous effusive eruptions in 1985, 2002, 2007 and 2014. The collapse occurred during a period of inflation of the summit cone and was preceded by increasing explosive activity and the enlargement of the crater. Weakness of the crater wall, increasing magmastatic pressure within the upper conduit induced by ascending magma and mechanical erosion caused by vent opening at the base of the crater wall and by lava fingering, are considered responsible for triggering the collapse on 12 January 2013 at Stromboli. We suggest that the combination of these factors might be a general mechanism to generate crater-wall collapse at active volcanoes.

  12. Screening: mapping medicine's temporal spaces.

    PubMed

    Armstrong, David

    2012-02-01

    This paper examines the history of population screening through an analysis of contemporary medical journals. The term was first used in the modern sense in the inter-war years to describe the school health examination which sought to identify the early signs of disease and abnormality, a strategy which was extended to new recruits during the Second World War. After the war, screening began to target those illnesses in the civilian population which had a clear temporal trajectory, especially 'chronic' illnesses. Since the 1980s, enthusiasm for population screening has declined within the medical community: opportunistic screening has seemed more appropriate for diseases with multifactorial aetiology, and those programmes which have survived have been increasingly challenged through an expanding analysis of their potential harms. In identifying the early precursors of clinical disease in apparently normal populations, however, screening heralded the emergence of a new form of clinical practice concerned with the surveillance of 'healthy' patients within the context of new temporal spaces of illness. © 2012 The Author. Sociology of Health & Illness © 2012 Foundation for the Sociology of Health & Illness/Blackwell Publishing Ltd.

  13. Semiquinone-bridged bisdithiazolyl radicals as neutral radical conductors.

    PubMed

    Yu, Xin; Mailman, Aaron; Lekin, Kristina; Assoud, Abdeljalil; Robertson, Craig M; Noll, Bruce C; Campana, Charles F; Howard, Judith A K; Dube, Paul A; Oakley, Richard T

    2012-02-01

    Semiquinone-bridged bisdithiazolyls 3 represent a new class of resonance-stabilized neutral radical for use in the design of single-component conductive materials. As such, they display electrochemical cell potentials lower than those of related pyridine-bridged bisdithiazolyls, a finding which heralds a reduced on-site Coulomb repulsion U. Crystallographic characterization of the chloro-substituted derivative 3a and its acetonitrile solvate 3a·MeCN, both of which crystallize in the polar orthorhombic space group Pna2(1), revealed the importance of intermolecular oxygen-to-sulfur (CO···SN) interactions in generating rigid, tightly packed radical π-stacks, including the structural motif found for 3a·MeCN in which radicals in neighboring π-stacks are locked into slipped-ribbon-like arrays. This architecture gives rise to strong intra- and interstack overlap and hence a large electronic bandwidth W. Variable-temperature conductivity measurements on 3a and 3a·MeCN indicated high values of σ(300 K) (>10(-3) S cm(-1)) with correspondingly low thermal activation energies E(act), reaching 0.11 eV in the case of 3a·MeCN. Overall, the strong performance of these materials as f = ½ conductors is attributed to a combination of low U and large W. Variable-temperature magnetic susceptibility measurements were performed on both 3a and 3a·MeCN. The unsolvated material 3a orders as a spin-canted antiferromagnet at 8 K, with a canting angle φ = 0.14° and a coercive field H(c) = 80 Oe at 2 K. © 2012 American Chemical Society

  14. Cystic kidneys in fetal Walker-Warburg syndrome with POMT2 mutation: Intrafamilial phenotypic variability in four siblings and review of literature.

    PubMed

    Nabhan, Marwa M; ElKhateeb, Nour; Braun, Daniela A; Eun, Sungho; Saleem, Sahar N; YungGee, Heon; Hildebrandt, Friedhelm; Soliman, Neveen A

    2017-10-01

    Walker-Warburg syndrome (WWS) is a severe form of congenital muscular dystrophy secondary to α-dystroglycanopathy with muscle, brain, and eye abnormalities often leading to death in the first weeks of life. It is transmitted in an autosomal recessive pattern, and has been linked to at least 15 different genes; including protein O-mannosyltransferase 1 (POMT1), protein O-mannosyltransferase 2 (POMT2), protein O-mannose beta-1,2-N acetylglucosaminyltransferase (POMGNT1), fukutin (FKTN), isoprenoid synthase domain-containing protein (ISPD), and other genes. We report on a consanguineous family with four consecutive siblings affected by this condition with lethal outcome in three (still birth), and termination of the fourth pregnancy based on antenatal MRI identification of brain and kidney anomalies that heralded proper and deep clinical phenotyping. The diagnosis of WWS was suggested based on the unique collective phenotype comprising brain anomalies in the form of lissencephaly, subcortical/subependymal heterotopia, and cerebellar hypoplasia shared by all four siblings; microphthalmia in one sibling; and large cystic kidneys in the fetus and another sibling. Other unshared neurological abnormalities included hydrocephalus and Dandy-Walker malformation. Whole exome sequencing of the fetus revealed a highly conserved missense mutation in POMT2 that is known to cause WWS with brain and eye anomalies.In conclusion, the heterogeneous clinical presentation in the four affected conceptions with POMT2 mutation expands the current clinical spectrum of POMT2-associated WWS to include large cystic kidneys; and confirms intra-familial variability in terms of brain, kidney, and eye anomalies. © 2017 Wiley Periodicals, Inc.

  15. Duckweed in bloom: the 2nd International Conference on Duckweed Research and Applications heralds the return of a plant model for plant biology.

    PubMed

    Lam, Eric; Appenroth, Klaus J; Michael, Todd; Mori, Kazuhiro; Fakhoorian, Tamra

    2014-04-01

    More than 50 participants from around the world congregated at Rutgers University for 4 days to discuss the latest advances in duckweed research and applications. Among other developments in the field, exciting new information related to duckweed including genome sequencing, improved genetic transformation, and the identification of a novel plant growth promoting substance from bacteria were reported.

  16. Southeast Asia Report, Number 1302

    DTIC Science & Technology

    1983-06-21

    Leaders 25 LAOS Foreign Ministry on S. African Bombing of Maputo 26 Briefs Foreign Minister Delegation 27 Soviet Transport Talks 27 Return From...Successor to Laurente (THE VISAYAN HERALD, 3 May 83) 46 Briefs NPA Leader Sick 47 Poor Turnout at Protest Rally 47 Rebels Abandon Cebu Safe Houses 47...THE NATION REVIEW, 10 May 83) 50 VOFA Urges SRV Compliance With UN Resolution (Voice of Free Asia, 25 May 83) 52 LCT Leader Says

  17. HERALD OF COMMUNICATIONS, 1963, VOL. 23, NO. 3 (275).

    DTIC Science & Technology

    all possible ways; communication facilities and computer technique help direct the industry ; carrier-telephony equipment of the type KV-12; widening of...facsimile appara tuses for the elimination of flaws in the process ing of telegrams; public supervision over the performance quality of communication workers ...simplified cable finder. Results of the completion for the best suggestion in the field of postal-service mechanization; and the training of postal workers at a polytechnic school.

  18. Translations on Narcotics and Dangerous Drugs No. 275.

    DTIC Science & Technology

    1976-12-09

    8217Vast’ Drug Network (HERALD, 25 Nov 76) l7 CHILE Marihuana Grower, Trafficker Arrested (LA TERCERA DE LA HORA, 10 Nov 76) 18 COLOMBIA...17 CHILE MARIHUANA. GROWER, TRAFFICKER ARRESTED Santiago LA TERCERA DE IA HORA in Spanish 10 Nov 76 p 27 [Text] Between 250,000 and 300,000...mountainous Aguas Negras region in the jurisdiction of Solano, where seven per- sons were arrested and a very complete laboratory was seized, together

  19. Bridging visible and telecom wavelengths with a single-mode broadband photon pair source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soeller, C.; Brecht, B.; Mosley, P. J.

    We present a spectrally decorrelated photon pair source bridging the visible and telecom wavelength regions. Tailored design and fabrication of a solid-core photonic crystal fiber (PCF) lead to the emission of signal and idler photons into only a single spectral and spatial mode. Thus no narrowband filtering is necessary and the heralded generation of pure photon number states in ultrafast wave packets at telecom wavelengths becomes possible.

  20. The Revolution in Military Affairs and Conflict Short of War

    DTIC Science & Technology

    1994-07-25

    an RMA in that portion of .the spectrum of conflict between peace and war. They conclude that .while the impact of purely military innovation will...combination of emerging technology and innovative ideas seen in the Gulf War seem to herald a genuine revolution in military affairs. The victory of... innovations . Rather than attempt to match the technological prowess of U.S. forces, future enemies will probably seek asymmetrical countermeasures designed

  1. Environmental forcing and Southern Ocean marine predator populations: effects of climate change and variability.

    PubMed

    Trathan, P N; Forcada, J; Murphy, E J

    2007-12-29

    The Southern Ocean is a major component within the global ocean and climate system and potentially the location where the most rapid climate change is most likely to happen, particularly in the high-latitude polar regions. In these regions, even small temperature changes can potentially lead to major environmental perturbations. Climate change is likely to be regional and may be expressed in various ways, including alterations to climate and weather patterns across a variety of time-scales that include changes to the long interdecadal background signals such as the development of the El Niño-Southern Oscillation (ENSO). Oscillating climate signals such as ENSO potentially provide a unique opportunity to explore how biological communities respond to change. This approach is based on the premise that biological responses to shorter-term sub-decadal climate variability signals are potentially the best predictor of biological responses over longer time-scales. Around the Southern Ocean, marine predator populations show periodicity in breeding performance and productivity, with relationships with the environment driven by physical forcing from the ENSO region in the Pacific. Wherever examined, these relationships are congruent with mid-trophic-level processes that are also correlated with environmental variability. The short-term changes to ecosystem structure and function observed during ENSO events herald potential long-term changes that may ensue following regional climate change. For example, in the South Atlantic, failure of Antarctic krill recruitment will inevitably foreshadow recruitment failures in a range of higher trophic-level marine predators. Where predator species are not able to accommodate by switching to other prey species, population-level changes will follow. The Southern Ocean, though oceanographically interconnected, is not a single ecosystem and different areas are dominated by different food webs. Where species occupy different positions in different regional food webs, there is the potential to make predictions about future change scenarios.

  2. Perceptual Plasticity for Auditory Object Recognition

    PubMed Central

    Heald, Shannon L. M.; Van Hedger, Stephen C.; Nusbaum, Howard C.

    2017-01-01

    In our auditory environment, we rarely experience the exact acoustic waveform twice. This is especially true for communicative signals that have meaning for listeners. In speech and music, the acoustic signal changes as a function of the talker (or instrument), speaking (or playing) rate, and room acoustics, to name a few factors. Yet, despite this acoustic variability, we are able to recognize a sentence or melody as the same across various kinds of acoustic inputs and determine meaning based on listening goals, expectations, context, and experience. The recognition process relates acoustic signals to prior experience despite variability in signal-relevant and signal-irrelevant acoustic properties, some of which could be considered as “noise” in service of a recognition goal. However, some acoustic variability, if systematic, is lawful and can be exploited by listeners to aid in recognition. Perceivable changes in systematic variability can herald a need for listeners to reorganize perception and reorient their attention to more immediately signal-relevant cues. This view is not incorporated currently in many extant theories of auditory perception, which traditionally reduce psychological or neural representations of perceptual objects and the processes that act on them to static entities. While this reduction is likely done for the sake of empirical tractability, such a reduction may seriously distort the perceptual process to be modeled. We argue that perceptual representations, as well as the processes underlying perception, are dynamically determined by an interaction between the uncertainty of the auditory signal and constraints of context. This suggests that the process of auditory recognition is highly context-dependent in that the identity of a given auditory object may be intrinsically tied to its preceding context. To argue for the flexible neural and psychological updating of sound-to-meaning mappings across speech and music, we draw upon examples of perceptual categories that are thought to be highly stable. This framework suggests that the process of auditory recognition cannot be divorced from the short-term context in which an auditory object is presented. Implications for auditory category acquisition and extant models of auditory perception, both cognitive and neural, are discussed. PMID:28588524

  3. Alpers–Huttenlocher syndrome: the role of a multidisciplinary health care team

    PubMed Central

    Saneto, Russell P

    2016-01-01

    Alpers–Huttenlocher syndrome (AHS) is a mitochondrial DNA-depletion syndrome. Age of onset is bimodal: early onset at 2–4 years and later adolescent onset at 17–24 years of age. Early development is usually normal, with epilepsy heralding the disorder in ~50% of patients. The onset of seizures is coupled with progressive cognitive decline. Hepatopathy is variable, and when present is a progressive dysfunction leading to liver failure in many cases. These features of seizures, cognitive degeneration, and hepatopathy represent the “classic triad” of AHS. However, most patients develop other system involvement. Therefore, although AHS is ultimately a lethal disorder, medical care is required for sustained quality of life. Frequently, additional organ systems – gastrointestinal, respiratory, nutritional, and psychiatric – abnormalities appear and need treatment. Rarely, cardiovascular dysfunction and even pregnancy complicate medical treatment. Optimal care requires a team of physicians and caretakers to make sure quality of life is optimized. The care team, together with the family and palliative care specialists, need to be in communication as the disease progresses and medical changes occur. Although the unpredictable losses of function challenge medical care, the team approach can foster the individual quality-of-life care needed for the patient and family. PMID:27555780

  4. Options and obstacles for designing a universal influenza vaccine.

    PubMed

    Jang, Yo Han; Seong, Baik Lin

    2014-08-18

    Since the discovery of antibodies specific to a highly conserved stalk region of the influenza virus hemagglutinin (HA), eliciting such antibodies has been considered the key to developing a universal influenza vaccine that confers broad-spectrum protection against various influenza subtypes. To achieve this goal, a prime/boost immunization strategy has been heralded to redirect host immune responses from the variable globular head domain to the conserved stalk domain of HA. While this approach has been successful in eliciting cross-reactive antibodies against the HA stalk domain, protective efficacy remains relatively poor due to the low immunogenicity of the domain, and the cross-reactivity was only within the same group, rather than among different groups. Additionally, concerns are raised on the possibility of vaccine-associated enhancement of viral infection and whether multiple boost immunization protocols would be considered practical from a clinical standpoint. Live attenuated vaccine hitherto remains unexplored, but is expected to serve as an alternative approach, considering its superior cross-reactivity. This review summarizes recent advancements in the HA stalk-based universal influenza vaccines, discusses the pros and cons of these approaches with respect to the potentially beneficial and harmful effects of neutralizing and non-neutralizing antibodies, and suggests future guidelines towards the design of a truly protective universal influenza vaccine.

  5. Options and Obstacles for Designing a Universal Influenza Vaccine

    PubMed Central

    Jang, Yo Han; Seong, Baik Lin

    2014-01-01

    Since the discovery of antibodies specific to a highly conserved stalk region of the influenza virus hemagglutinin (HA), eliciting such antibodies has been considered the key to developing a universal influenza vaccine that confers broad-spectrum protection against various influenza subtypes. To achieve this goal, a prime/boost immunization strategy has been heralded to redirect host immune responses from the variable globular head domain to the conserved stalk domain of HA. While this approach has been successful in eliciting cross-reactive antibodies against the HA stalk domain, protective efficacy remains relatively poor due to the low immunogenicity of the domain, and the cross-reactivity was only within the same group, rather than among different groups. Additionally, concerns are raised on the possibility of vaccine-associated enhancement of viral infection and whether multiple boost immunization protocols would be considered practical from a clinical standpoint. Live attenuated vaccine hitherto remains unexplored, but is expected to serve as an alternative approach, considering its superior cross-reactivity. This review summarizes recent advancements in the HA stalk-based universal influenza vaccines, discusses the pros and cons of these approaches with respect to the potentially beneficial and harmful effects of neutralizing and non-neutralizing antibodies, and suggests future guidelines towards the design of a truly protective universal influenza vaccine. PMID:25196381

  6. Aging with spinal cord injury: changes in selected health indices and life satisfaction.

    PubMed

    Charlifue, Susan; Lammertse, Daniel P; Adkins, Rodney H

    2004-11-01

    To document the impact of age, age at injury, years postinjury, and injury severity on changes over time in selected physical and psychosocial outcomes of people aging with spinal cord injury (SCI), and to identify the best predictors of these outcomes. Retrospective cross-sectional and longitudinal examination of people with SCI. Follow-up of people who received initial rehabilitation in a regional Model Spinal Cord Injury System. People who meet the inclusion criteria for the National Spinal Cord Injury Database were studied at 5, 10, 15, 20, and 25 years postinjury. Not applicable. Number of pressure ulcers, number of times rehospitalized, number of days rehospitalized, perceived health status, satisfaction with life, and pain during the most recent follow-up year. The number of days rehospitalized and frequency of rehospitalizations decreased and the number of pressure ulcers increased as time passed. For the variables of pressure ulcers, poor perceived health, the perception of pain and lower life satisfaction, the best predictor of each outcome was the previous existence or poor rating of that same outcome. Common complications of SCI often herald the recurrence of those same complications at a later point in time, highlighting the importance of early intervention to prevent future health and psychosocial difficulties.

  7. Thinner cortex in patients with subjective cognitive decline is associated with steeper decline of memory.

    PubMed

    Verfaillie, Sander C J; Slot, Rosalinde E; Tijms, Betty M; Bouwman, Femke; Benedictus, Marije R; Overbeek, Jozefien M; Koene, Teddy; Vrenken, Hugo; Scheltens, Philip; Barkhof, Frederik; van der Flier, Wiesje M

    2018-01-01

    We aimed to investigate associations between regional cortical thickness and rate of decline over time in 4 cognitive domains in patients with subjective cognitive decline (SCD). We included 233 SCD patients with the total number of 654 neuropsychological assessments (median = 3, range = 2-8) and available baseline magnetic resonance imaging from the Amsterdam Dementia Cohort (125 males, age: 63 ± 9, Mini-Mental State Examination score: 28 ± 2). We assessed longitudinal cognitive functioning at baseline and follow-up in 4 cognitive domains (composite Z-scores): memory, attention, executive function, and language. Thickness (millimeter) was estimated using FreeSurfer for frontal, temporal, parietal, cingulate, and occipital cortices. We used linear mixed models to estimate effects of cortical thickness on cognitive performance (dependent variables). There were no associations between cortical thickness and baseline cognition, but a faster subsequent rate of memory loss was associated with thinner cortex of the frontal [β (SE) = 0.20 (0.07)], temporal [β (SE) = 0.18 (0.07)], and occipital [β (SE) = 0.22 (0.09)] cortices (all p < 0.05 FDR ). These findings illustrate that early cortical changes, particularly in the temporal cortex, herald incipient cognitive decline related to neurodegenerative diseases, most prominently Alzheimer's disease. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. The next decade of space robotics

    NASA Technical Reports Server (NTRS)

    Lavery, Dave; Weisbin, Charles

    1994-01-01

    In the same way that the launch of Yuri Gagarin in April 1961 announced the beginning of human space flight, last year's flight of the German ROTEX robot flight experiment is heralding the start of a new era of space robotics. After a gap of twelve years since the introduction of a new capability in space remote manipulation, ROTEX is the first of at least ten new robotic systems and experiments which will fly before the year 2000.

  9. Encouraging Democratic Transitions: The Problematic Impact of United States’ Involvement

    DTIC Science & Technology

    1991-06-20

    more abstractly, democracy is consolidated when uncertainty is institutionalized: nobody can control the outcomes of the political process ex post ...for Change in Cuba", Miami Herald, May 27, 1990. See also, Al Kamen, "US Encourages Soviets to Aid Salvadoran Talks". Washington Post , October 18, 1990...Report, September 13, 1990, p. 10, and "Cuba Cuts Fuel Consumption as Soviet Oil Deliveries Fall", Washington Post , August 30, 1990. 20 not even call

  10. The Necessity for Smart Power: How a SWIFT Kick Hurts

    DTIC Science & Technology

    2013-03-01

    South America. Among other investments, the Chinese are providing subsidized financing to the telecommunication company Huawei , “an opaque...April 03, 2012. http://voices.halabol.com/2012/04/02/dollar%E2%80%99s-authority-rip (accessed March 11, 2013). 14Malcolm Maiden, “ Huawei a Security...Risk By Any Gauge,” Sydney Morning Herald, March 28, 2012, http://www.smh.com.au/business/ huawei -a-security-risk-by-any-gauge-20120327- 1vwnu.html

  11. China: Suspected Acquisition of U.S. Nuclear Weapon Secrets

    DTIC Science & Technology

    2006-02-01

    Benjamin Kang, “China Nuclear Halt May Stem From Deal,” Reuters, July 30, 1996; Robert Karniol, “Nuclear Blast Heralds A Chinese Moratorium,” Jane’s Defense...Leak,” New York Times, April 8, 1999. 12 FBI, “Statement by FBI Director Robert S. Mueller,” April 9, 2003; Katrina Leung Affidavit; James J. Smith...the appropriate congressional committees and the White House on April 21, 1999. Robert Walpole, the National Intelligence Officer for Strategic and

  12. The Coast Artillery Journal. Volume 68, Number 5, May 1928

    DTIC Science & Technology

    1928-05-01

    barren victories into decisive successes. In the battle of the future no other method of command will be possible, so the sooner officersare trained to it...seaboard, but competition threatened. The settlement of Jamestown to the south and of Plymouth to the north heralded the ultimate en~oachment of the... Plymouth , and Con- necticut. One hundred and eighty or ninety guns had been mounted on Fort Willem Hendrick and about the town. ~ews of the peace arriving

  13. Colombia’s Conflicts: The Spillover Effects of a Wider War

    DTIC Science & Technology

    2002-10-01

    a summary of the history and impact of civil violence on Colombian history, see Comision de estudios sobre la violencia, Colombia: Violencia y...Brasilia pie acapos del Cartel de brasil,” El Nuevo Herald, March 27, 2001; Mendel, p. 7. 87. Quoted in Gentleman, pp. 28-29. 88. “Tracion en el mercado ...guerrilla groups, the leftist Revolutionary Armed Forces of Colombia (FARC) and Ejercito de Liberacion Nacional (ELN) and the rightist Auto Defensas

  14. Planning for War Termination with China

    DTIC Science & Technology

    2012-05-04

    proximate to the continental power of central Asia. 16 Forward basing, presence and the ability to play the “away game ” versus defending from the...designed to target an aircraft carrier under way at sea. Andrew S Erickson and David D. Yang. "On the Verge of a Game -Changer." Proceedings (May 2009...China begin war games near Jhelum." Internatinoal Herald Tribune, Pakistan, (November 15, 2011). 82 Kenneth Lieberthal, "The American Pivot to Asia

  15. The Coast Artillery Journal. Volume 59, Number 2, August 1923

    DTIC Science & Technology

    1923-08-01

    writers and artists have used it as a device for Joan of Arc. Heraldically the phoenix is always represented as an eagle rising from flames, and in...181) THE BULLETI~ BOARD 185 graphs of two artistic pieces in sterling silver which have just been completed by the Bailey Banks and Biddle Company...the supper hour the gatheriIU! again assembled on the parade ground to "itness a demonstration of cornbin~ gymnastics and calisthenics by the entire

  16. Honduran-U.S. Relations

    DTIC Science & Technology

    2009-08-04

    Miami Herald, July 16, 2009; “Informe Preliminar: Violaciones a Derechos Humanos en el Marco del Golpe de Estado en Honduras,” Comité de Familiares de...Detenidos Desaparecidos en Honduras (CONFADEH), July 15, 2009; “Reporte de Violaciones a Derechos Humanos Después del Golpe de Estado Político-Militar...del 28 de Junio de 2009,” Centro de Investigacion y Promocion de los Derechos Humanos (CIPRODEH), July 17, 2009. 31 For more on the U.S. response

  17. Clinical Pharmacology & Therapeutics: Past, Present and Future

    PubMed Central

    Waldman, SA; Terzic, A

    2016-01-01

    Clinical Pharmacology & Therapeutics (CPT), the definitive and timely source for advances in human therapeutics, transcends the drug discovery, development, regulation and utilization continuum to catalyze, evolve and disseminate discipline-transformative knowledge. Prioritized themes and multidisciplinary content drive the science and practice of clinical pharmacology, offering a trusted point of reference. An authoritative herald across global communities, CPT is a timeless information vehicle at the vanguard of discovery, translation and application ushering therapeutic innovation into modern health care. PMID:28194770

  18. Political and Legal Responses to Proposition 13 in California

    DTIC Science & Technology

    1980-01-01

    govern- ments. iii SUMMARY The passage of Proposition 13, the Jarvis-Gann initiative, by a 2-to- l margin was heralded by some as the cutting...perience with the passage of Proposition 13 in 1978 and the Gann initiative in 1979, it is likely that this ballot measure will pass. l Then local...91 I. INTRODUCTION June 6, 1978, marked the start of what some saw as a national tax revolt. By a 2-to- l margin

  19. Towards a New Russia Policy

    DTIC Science & Technology

    2008-02-01

    February 5, 2007; Fyodor Lukanov, “Where to Focus If Your Are Expecting Change,” Moscow Times, February 7, 2007; Rodriguez. 114 59. Audrius Baciulis...International Herald Tribune, February 27, 2006, p. 2, retrieved from Lexis-Nexis; “Russia: Friend or Foe of the USA ?” prvda.ru, February 27, 2006, from...Street Journal, June 28, 2004, 132 p. 9; Bill Gertz, “ USA Considers Reactor Deal With North Korea,” Washington Times, May 19, 2004, cited by Aidan

  20. Business Sector Development: A Critical Component of an Operational Approach to Stability Operations

    DTIC Science & Technology

    2010-11-30

    CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR (S) Major Travis J. Lindberg, United States Army 5d. PROJECT... nature of the local free-market system, to include the much-heralded National Solidarity Programme, will inevitably produce benefits whose costs are... author , and do not represent the views of the US Army School of Advanced Military Studies, the US Army Command and General Staff College, the United

  1. Mortality patterns associated with the 1918 influenza pandemic in Mexico: evidence for a spring herald wave and lack of pre-existing immunity in older populations

    PubMed Central

    Chowell, Gerardo; Viboud, Cécile; Simonsen, Lone; Miller, Mark A.; Acuna-Soto, Rodolfo

    2010-01-01

    Background While the mortality burden of the devastating 1918 influenza pandemic has been carefully quantified in the US, Japan, and European countries, little is known about the pandemic experience elsewhere. Here, we compiled extensive archival records to quantify the pandemic mortality patterns in two Mexican cities, Mexico City and Toluca. Methods We applied seasonal excess mortality models to age-specific respiratory mortality rates for 1915–1920 and quantified the reproduction number from daily data. Results We identified 3 pandemic waves in Mexico City in spring 1918, fall 1918, and winter 1920, characterized by unusual excess mortality in 25–44 years old. Toluca experienced 2-fold higher excess mortality rates than Mexico City, but did not have a substantial 3rd wave. All age groups including those over 65 years experienced excess mortality during 1918–20. Reproduction number estimates were below 2.5 assuming a 3-day generation interval. Conclusion Mexico experienced a herald pandemic wave with elevated young adult mortality in spring 1918, similar to the US and Europe. In contrast to the US and Europe, there was no mortality sparing in Mexican seniors, highlighting potential geographical differences in pre-existing immunity to the 1918 virus. We discuss the relevance of our findings to the 2009 pandemic mortality patterns. PMID:20594109

  2. An Unexpected Surge in Plasma BKPyV Viral Load Heralds the Development of BKPyV-Associated Metastatic Bladder Cancer in a Lung Transplant Recipient With BKPyV Nephropathy.

    PubMed

    Kuppachi, S; Holanda, D; Eberlein, M; Alexiev, B; Tyler, A J; Wissel, M C; Kleiboeker, S B; Thomas, C P

    2017-03-01

    We report a lung transplant recipient who developed BK polyoma virus (BKPyV) DNAemia and BKPyV nephropathy. With careful management of his immunosuppression he achieved significant reduction in BKPyV DNAemia and stabilization of his kidney function. He later developed a high-grade bladder cancer and shortly thereafter he experienced a major upsurge in the level of BKPyV DNAemia that coincided with the discovery of hepatic metastasis. Retrospectively, the bladder cancer and the hepatic secondary tumor stained uniformly for SV40 large T antigen, and the BKPyV DNA sequences identified in plasma corresponded to BKPyV DNA within hepatic tissue, indicating that the spike in BKPyV load was likely derived from the circulating tumor cells or cell-free tumor DNA following metastases of a BKV-associated cancer. To the best of our knowledge, this is the first description of a surge in BKPyV load in a patient with controlled BKPyVN that heralded the appearance of a metastatic urothelial malignancy. This report discusses the literature on BKPyV-associated malignancies and the possibility that unexplained increases in BKPyV DNAemia may be a biomarker for metastatic BKPyV-related urothelial cancer. © Copyright 2016 The American Society of Transplantation and the American Society of Transplant Surgeons.

  3. Molecular Epidemiology of Adenovirus Type 7 in the United States, 1966–20001

    PubMed Central

    Xu, Wanhong; Gerber, Susan I.; Gray, Gregory C.; Schnurr, David; Kajon, Adriana E.; Anderson, Larry J.

    2002-01-01

    Genetic variation among 166 isolates of human adenovirus 7 (Ad7) obtained from 1966 to 2000 from the United States and Eastern Ontario, Canada, was determined by genome restriction analysis. Most (65%) isolates were identified as Ad7b. Two genome types previously undocumented in North America were also identified: Ad7d2 (28%), which first appeared in 1993 and was later identified throughout the Midwest and Northeast of the United States and in Canada; and Ad7h (2%), which was identified only in the U.S. Southwest in 1998 and 2000. Since 1996, Ad7d2 has been responsible for several civilian outbreaks of Ad7 disease and was the primary cause of a large outbreak of respiratory illness at a military recruit training center. The appearance of Ad7d2 and Ad7h in North America represents recent introduction of these viruses from previously geographically restricted areas and may herald a shift in predominant genome type circulating in the United States. PMID:11927024

  4. Florid urticarial vasculitis heralding a flare up of ulcerative colitis.

    PubMed

    Boules, Evon; Lyon, Calum

    2014-12-22

    A 75-year-old man with ulcerative colitis (UC) and diet controlled diabetes mellitus presented with a 3-week history of slightly itchy, red plaques on both lower limbs ascending gradually to cover the trunk and arms. One week later, he developed a flare up of his UC. Routine blood tests showed modest drop in haemoglobin (122 g/L) and C reactive protein (85 mg/L). Serology was remarkable for high antiproteinase 3 (c-ANCA). Serum electrophoresis showed a mildly positive paraprotein band (γ region). Stool culture was negative. Urine analysis showed proteinuria. Skin biopsy showed features of urticarial vasculitis (UV). He underwent a flexible sigmoidoscopy after the flare up showed mildly active UC. The patient was given hydrocortisone for 7 days and then prednisolone. Both rash and UC subsided. Electrophoresis was repeated 4 weeks later showing normal pattern. Prednisolone has been gradually reduced. Although rare, UV can be considered as one of the skin manifestations of UC. 2014 BMJ Publishing Group Ltd.

  5. Passive measurement-device-independent quantum key distribution with orbital angular momentum and pulse position modulation

    NASA Astrophysics Data System (ADS)

    Wang, Lian; Zhou, Yuan-yuan; Zhou, Xue-jun; Chen, Xiao

    2018-03-01

    Based on the orbital angular momentum and pulse position modulation, we present a novel passive measurement-device-independent quantum key distribution (MDI-QKD) scheme with the two-mode source. Combining with the tight bounds of the yield and error rate of single-photon pairs given in our paper, we conduct performance analysis on the scheme with heralded single-photon source. The numerical simulations show that the performance of our scheme is significantly superior to the traditional MDI-QKD in the error rate, key generation rate and secure transmission distance, since the application of orbital angular momentum and pulse position modulation can exclude the basis-dependent flaw and increase the information content for each single photon. Moreover, the performance is improved with the rise of the frame length. Therefore, our scheme, without intensity modulation, avoids the source side channels and enhances the key generation rate. It has greatly utility value in the MDI-QKD setups.

  6. Emergence of fatal avian influenza in New England harbor seals

    USGS Publications Warehouse

    Anthony, S.J.; St. Leger, J. A.; Pugliares, K.; Ip, Hon S.; Chan, J.M.; Carpenter, Z.W.; Navarrete-Macias, I.; Sanchez-Leon, M.; Saliki, J.T.; Pedersen, J.; Karesh, W.; Daszak, P.; Rabadan, R.; Rowles, T.; Lipkin, W.I.

    2012-01-01

    From September to December 2011, 162 New England harbor seals died in an outbreak of pneumonia. Sequence analysis of postmortem samples revealed the presence of an avian H3N8 influenza A virus, similar to a virus circulating in North American waterfowl since at least 2002 but with mutations that indicate recent adaption to mammalian hosts. These include a D701N mutation in the viral PB2 protein, previously reported in highly pathogenic H5N1 avian influenza viruses infecting people. Lectin staining and agglutination assays indicated the presence of the avian-preferred SAα-2,3 and mammalian SAα-2,6 receptors in seal respiratory tract, and the ability of the virus to agglutinate erythrocytes bearing either the SAα-2,3 or the SAα-2,6 receptor. The emergence of this A/harbor seal/Massachusetts/1/2011 virus may herald the appearance of an H3N8 influenza clade with potential for persistence and cross-species transmission.

  7. The coming paradigm shift: A transition from manual to automated microscopy.

    PubMed

    Farahani, Navid; Monteith, Corey E

    2016-01-01

    The field of pathology has used light microscopy (LM) extensively since the mid-19(th) century for examination of histological tissue preparations. This technology has remained the foremost tool in use by pathologists even as other fields have undergone a great change in recent years through new technologies. However, as new microscopy techniques are perfected and made available, this reliance on the standard LM will likely begin to change. Advanced imaging involving both diffraction-limited and subdiffraction techniques are bringing nondestructive, high-resolution, molecular-level imaging to pathology. Some of these technologies can produce three-dimensional (3D) datasets from sampled tissues. In addition, block-face/tissue-sectioning techniques are already providing automated, large-scale 3D datasets of whole specimens. These datasets allow pathologists to see an entire sample with all of its spatial information intact, and furthermore allow image analysis such as detection, segmentation, and classification, which are impossible in standard LM. It is likely that these technologies herald a major paradigm shift in the field of pathology.

  8. Graphing trillions of triangles.

    PubMed

    Burkhardt, Paul

    2017-07-01

    The increasing size of Big Data is often heralded but how data are transformed and represented is also profoundly important to knowledge discovery, and this is exemplified in Big Graph analytics. Much attention has been placed on the scale of the input graph but the product of a graph algorithm can be many times larger than the input. This is true for many graph problems, such as listing all triangles in a graph. Enabling scalable graph exploration for Big Graphs requires new approaches to algorithms, architectures, and visual analytics. A brief tutorial is given to aid the argument for thoughtful representation of data in the context of graph analysis. Then a new algebraic method to reduce the arithmetic operations in counting and listing triangles in graphs is introduced. Additionally, a scalable triangle listing algorithm in the MapReduce model will be presented followed by a description of the experiments with that algorithm that led to the current largest and fastest triangle listing benchmarks to date. Finally, a method for identifying triangles in new visual graph exploration technologies is proposed.

  9. The Impact of Contemporary Conflicts Between Latin American Nations on Regional Stability and Cooperation

    DTIC Science & Technology

    1990-02-12

    of Interamerican Studies and World Affairs, Winter 88-89, pp 139-170. 20. " Bogota y Caracas Acuerdan Med iac ion, " Nuevo Heral1d (Miami), 29 March...Banco Central del Ecuador. El Ecuadur in La OPEP. Quito: Ediciones Bancentral, 1979. 8. "Bogota y Caracas Acuerdan Mediacion." Nuevo Herald (Miami...Sur. Revista Chileno de Geooolitica, Vol. 3, April 1989, pp 59-98. 69. Porse, Ernesto G. "El Conflicto de los Grandes Proyectos Hidroelectricos

  10. Chronology of KSC and KSC related events for 1983

    NASA Technical Reports Server (NTRS)

    Nail, K., Jr. (Compiler)

    1984-01-01

    Materials for this chronology were selected from Aviation Week and Space Technology, Defense Daily, Miami Herald, Sentinel Star (Orlando), Today (Cocoa), Spaceport News (KSC), NASA News Releases, and other sources. The document is intended to serve as a record of KSC events and as a reference source for historians and other researchers. Arrangement is by month; items are by date of the published sources. Actual date of the event may be indicated in parenthesis, when the article itself does not make that information explicit.

  11. Teachable Moments: When Protests Erupted Following the Publication of an Anti-Reparations Ad in a Campus Newspaper, Brown University President Ruth Simmons Decided Her Community Could Benefit from Taking a Closer Look at the University's Historical Ties to Slavery

    ERIC Educational Resources Information Center

    Hamilton, Kendra

    2005-01-01

    It all started as a rather ran-of-the-mill campus controversy over race and slavery: an anti-reparations ad ran in The Brown Daily Herald; students cried foul, formed human chains and demanded "reparations" in the form of free advertising for the opposing side; still others responded with shouts of "political correctness." But then something…

  12. VLSI (Very Large Scale Integrated Circuits) Design with the MacPitts Silicon Compiler.

    DTIC Science & Technology

    1985-09-01

    the background. If the algorithm is not fully debugged, then issue instead macpitts basename herald so MacPitts diagnostics and Liszt diagnostics both...command interpreter. Upon compilation, however, the following LI!F compiler ( Liszt ) diagnostic results, Error: Non-number to minus nil where the first...language used in the MacPitts source code. The more instructive solution is to write the Franz LISP code to decide if a jumper wire is needed, and if so, to

  13. Less reality, more security

    NASA Astrophysics Data System (ADS)

    Ekert, Artur

    2009-09-01

    On 25 March 1935 John Tate, the then editor of Physical Review, received a paper that Einstein had co-authored with Boris Podolsky and Nathan Rosen, his younger colleagues at Princeton. The logbooks of Physical Review show that the EPR paper, as it has since become known, bypassed the refereeing process and went straight to press. Four printed pages of beautifully constructed argument appeared in the 15 May issue. They were heralded by a brief article in the New York Times titled "Einstein attacks quantum theory". And so he did.

  14. Choloperitoneum causes extensive coloring of the abdominal wall skin.

    PubMed

    Mathioulakis, Stavros; Liverakou, Evangelia; Gourgiotis, Stavros; Salemis, Nikolaos S

    2014-10-01

    Laparoscopic cholecystectomy, because it is the less invasive surgical procedure, has been established as the procedure of choice for the treatment of patients with symptomatic gallbladder stones. However, bile leakage after laparoscopic cholecystectomy should not be overlooked. It is generally due to a minor biliary complication, although it can sometimes herald a major duct injury. Bile leakage rates of 1.2% to 4.0% in laparoscopic cholecystectomies have been reported, which are higher than the incidence with open cholecystectomies.

  15. Beyond Incrementalism? SCHIP and the politics of health reform.

    PubMed

    Oberlander, Jonathan B; Lyons, Barbara

    2009-01-01

    When Congress enacted the State Children's Health Insurance Program (SCHIP) in 1997, it was heralded as a model of bipartisan, incremental health policy. However, despite the program's achievements in the ensuing decade, SCHIP's reauthorization triggered political conflict, and efforts to expand the program stalemated in 2007. The 2008 elections broke that stalemate, and in 2009 the new Congress passed, and President Barack Obama signed, legislation reauthorizing SCHIP. Now that attention is turning to comprehensive health reform, what lessons can reformers learn from SCHIP's political adventures?

  16. KSC-07pd0880

    NASA Image and Video Library

    2007-04-11

    KENNEDY SPACE CENTER, FLA. -- A taste of spring is heralded by the blooming of these flowers near a riverbank on Kennedy Space Center. KSC shares a boundary with the Merritt Island Wildlife Nature Refuge. The refuge is a habitat for more than 310 species of birds, 25 mammals, 117 fishes and 65 amphibians and reptiles. In addition, the Refuge supports 19 endangered or threatened wildlife species on Federal or State lists, more than any other single refuge in the U.S. Photo credit: NASA/Dimitri Gerondidakis

  17. Heralded Quantum Gate between Remote Quantum Memories

    DTIC Science & Technology

    2009-06-25

    emission fre- quency. Second, the geometrical modes from the two fibers are matched to better than 98% as characterized with laser light. Third, the...remains in the trap for several weeks. Doppler-cooling by laser light slightly red detuned from the 2S1=2 $ 2P1=2 transition at 369.5 nm localizes the ions...state decays to the metastable 2D3=2 level. This level is depopulated with a laser near 935.2 nm to maintain efficient cooling and state detection. We

  18. Three-photon N00N states generated by photon subtraction from double photon pairs.

    PubMed

    Kim, Heonoh; Park, Hee Su; Choi, Sang-Kyung

    2009-10-26

    We describe an experimental demonstration of a novel three-photon N00N state generation scheme using a single source of photons based on spontaneous parametric down-conversion (SPDC). The three-photon entangled state is generated when a photon is subtracted from a double pair of photons and detected by a heralding counter. Interference fringes measured with an emulated three-photon detector reveal the three-photon de Broglie wavelength and exhibit visibility > 70% without background subtraction.

  19. KSC-04pd0824

    NASA Image and Video Library

    2004-04-12

    KENNEDY SPACE CENTER, FLA. - Center Director Jim Kennedy (right) talks to a reporter from the Miami Herald about his visit to Carol City Elementary School, a NASA Explorer School, in Miami, Fla. Kennedy is sharing America’s new vision for space exploration with the next generation of explorers. He is talking with students about our destiny as explorers, NASA’s stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space.

  20. Primary care--opportunities and threats. Developing professional knowledge: making primary care education and research more relevant.

    PubMed Central

    Pearson, P.; Jones, K.

    1997-01-01

    The trio of recent government white papers heralds a new world for primary care. Many changes in the education of future primary health care professionals and in the research ethos of the discipline will be needed to realise this vision. New skills and attitudes, not least in multidisciplinary working; lifelong learning; and greater understanding of and participation in primary care research will have to emerge from educational efforts in the next few years. PMID:9081008

  1. Microtubules and cellulose microfibrils: how intimate is their relationship?

    PubMed

    Emons, Anne Mie C; Höfte, Herman; Mulder, Bela M

    2007-07-01

    The recent visualization of the motion of fluorescently labeled cellulose synthase complexes by Alexander Paredez and colleagues heralds the start of a new era in the science of the plant cell wall. Upon drug-induced complete depolymerization, the movement of the complexes does not become disordered but instead establishes an apparently self-organized novel pattern. The ability to label complexes in vivo has provided us with the ideal tool for tackling the intriguing question of the underlying default mechanisms at play.

  2. Japan’s Emerging Role as an Asian-Pacific Power.

    DTIC Science & Technology

    1986-06-01

    34Nakasone’s External Policy." Asia Pacfic Community 25 (Summer 1984): 28-40. 114. Colbert , Evelyn. "Japan and the Republic of Korea." Asian Survey 3...129. The Korea Herald, May 7, 1985. 129 130. Jo, Yung-hwan. "Two Koreas Unification." Asia Pacific Community 23 (Winter 1984): 75-85. 131. Colbert ...Pacific Community 25 (Summer 1984): 51-57. 179. Reischauer, Edwin 0. The United States and Japan. New York: The Viking Press, Inc., 1968. 133 . r

  3. Milestones of Lynch syndrome: 1895-2015.

    PubMed

    Lynch, Henry T; Snyder, Carrie L; Shaw, Trudy G; Heinen, Christopher D; Hitchins, Megan P

    2015-03-01

    Lynch syndrome, which is now recognized as the most common hereditary colorectal cancer condition, is characterized by the predisposition to a spectrum of cancers, primarily colorectal cancer and endometrial cancer. We chronicle over a century of discoveries that revolutionized the diagnosis and clinical management of Lynch syndrome, beginning in 1895 with Warthin's observations of familial cancer clusters, through the clinical era led by Lynch and the genetic era heralded by the discovery of causative mutations in mismatch repair (MMR) genes, to ongoing challenges.

  4. 17th Annual ALS Users' Association Meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Robinson, Art; Tamura, Lori

    2004-11-29

    It's not exactly Russian roulette, but scheduling October events outdoors is not risk-free, even in usually sunny California. An overflow crowd of more than 400 registered users, ALS staff, and vendors enjoyed a full indoor program featuring science highlights and workshops spread over two and a half days from October 18 to October 20. However, a major storm, heralding the onset of the San Francisco Bay Area rainy season, posed a few weather challenges for the events on the ALS patio.

  5. Clinical Pharmacology & Therapeutics: Past, Present, and Future.

    PubMed

    Waldman, S A; Terzic, A

    2017-03-01

    Clinical Pharmacology & Therapeutics (CPT), the definitive and timely source for advances in human therapeutics, transcends the drug discovery, development, regulation, and utilization continuum to catalyze, evolve, and disseminate discipline-transformative knowledge. Prioritized themes and multidisciplinary content drive the science and practice of clinical pharmacology, offering a trusted point of reference. An authoritative herald across global communities, CPT is a timeless information vehicle at the vanguard of discovery, translation, and application ushering therapeutic innovation into modern healthcare. © 2017 American Society for Clinical Pharmacology and Therapeutics.

  6. Hardening: Australian for Transformation

    DTIC Science & Technology

    2004-01-01

    German design Leopard II or the US M1A1 Abrams. See Ian McPhedran “Hill in talks to buy Leopards, The Herald Sun. 09 January 2004, [On-line]; available...Government of the need to buy new tanks. 128 In complex war fighting, one cannot always expect to start from a position of advantage. An army’s...white paper, said he had been told that the decision to buy the Abrams "has in effect been made". The $600 million price tag was high and could be

  7. Entanglement with negative Wigner function of almost 3,000 atoms heralded by one photon.

    PubMed

    McConnell, Robert; Zhang, Hao; Hu, Jiazhong; Ćuk, Senka; Vuletić, Vladan

    2015-03-26

    Quantum-mechanically correlated (entangled) states of many particles are of interest in quantum information, quantum computing and quantum metrology. Metrologically useful entangled states of large atomic ensembles have been experimentally realized, but these states display Gaussian spin distribution functions with a non-negative Wigner quasiprobability distribution function. Non-Gaussian entangled states have been produced in small ensembles of ions, and very recently in large atomic ensembles. Here we generate entanglement in a large atomic ensemble via an interaction with a very weak laser pulse; remarkably, the detection of a single photon prepares several thousand atoms in an entangled state. We reconstruct a negative-valued Wigner function--an important hallmark of non-classicality--and verify an entanglement depth (the minimum number of mutually entangled atoms) of 2,910 ± 190 out of 3,100 atoms. Attaining such a negative Wigner function and the mutual entanglement of virtually all atoms is unprecedented for an ensemble containing more than a few particles. Although the achieved purity of the state is slightly below the threshold for entanglement-induced metrological gain, further technical improvement should allow the generation of states that surpass this threshold, and of more complex Schrödinger cat states for quantum metrology and information processing. More generally, our results demonstrate the power of heralded methods for entanglement generation, and illustrate how the information contained in a single photon can drastically alter the quantum state of a large system.

  8. Near-surface elastic changes in the Ross Ice Shelf arising from transient storm and melt forcing observed with high-frequency ambient seismic noise

    NASA Astrophysics Data System (ADS)

    Chaput, J.; Aster, R. C.; Baker, M. G.; Gerstoft, P.; Bromirski, P. D.; Nyblade, A.; Stephen, R. A.; Wiens, D.

    2017-12-01

    Ice shelf collapse can herald subsequent grounded ice instability. However, robust understanding of external mechanisms capable of triggering rapid changes remains elusive. Improved understanding therefore requires improved remote and in-situ measurements of ice shelf properties. Using nearly three years of continuous data from a recently deployed 34-station broadband seismic array on the Ross Ice Shelf, we analyze persistent temporally varying, anisotropic near-surface resonant wave modes at frequencies above 1 Hz that are highly sensitive to small changes in elastic shelf properties to depths of tens of m. We further find that these modes exhibit both progressive (on the scale of months) and rapid (on the scale of hours) changes in frequency content. The largest and most rapid excursions are associated with forcing from local storms, and with a large regional ice shelf melt event in January 2016. We hypothesize that temporally variable behavior of the resonance features arises from wind slab formation during storms and/or to porosity changes, and to the formation of percolation-related refrozen layers and thinning in the case of surface melting. These resonance variations can be reproduced and inverted for structural changes using numerical wave propagation models, and thus present an opportunity for 4-D structural monitoring of shallow ice shelf elasticity and structure using long-duration seismic recordings.

  9. VizieR Online Data Catalog: XZ Catalog of Zodiacal Stars (XZ80Q) (Herald, 2003)

    NASA Astrophysics Data System (ADS)

    Herald, D.

    2003-11-01

    The XZ catalog was created at the U.S. Naval Observatory in 1977 by Richard Schmidt and Tom Van Flandern, primarily for the purpose of generating predictions of lunar occultations, and for analyzing timings of these events. It was designed to include all stars within 6d 40' of the ecliptic (the "Zodiac"), which is as far as the Moon's limb can ever get as seen from anywhere on the Earth's surface, leaving some margin for stellar proper motions and change in the obliquity of the ecliptic over the course of three centuries. The original version contained 32,221 entries; since that time, many changes have been made in succeeding versions, including better positions and proper motions, and the elimination and addition of stars. Details about the history of XZ catalog can be found in the "doc.txt" file. The XZ80Q revision has been developed from XZ80P, which was created by Mitsuru Soma. It is now complete over the Zodiac for stars down to visual magnitude 12.0. The "xz80q.dat" file contains the list of stars making the catalog; additional files provide details about double and variable stars included in the XZ80Q. The catalog includes also lists of the various existing names of the stars. (11 data files).

  10. Salmonella Urinary Tract Infection Heralding Thoracic Mycotic Aneurysm: Case Report as Medical Apology

    PubMed Central

    White, Jennifer L.; Golfus, Gabriel R.; Sadosty, Annie T.

    2017-01-01

    We report a case as a patient apology as a means of teaching other physicians about a unique presentation of a rare disease. Salmonella species are unusually isolated organisms in urine. In the case described, appreciation for the rarity of Salmonella species in the urine facilitated recognition of a serious disseminated Salmonella infection. Physicians should consider disseminated Salmonella infection, as was found in a patient with an aortic mycotic an eurysm, after isolation of Salmonella in urine despite an initially benign clinical presentation.

  11. Into the Curriculum. Creative Dramatics: Valentine Lip Sync Book Charades; Language Arts/Social Studies: Found Poetry from Primary Sources; Reading/Language Arts: A Thematic Activity To Herald in the New Year; Science: Asian Elephant Life Cycles; Social Studies: Conservation of Animal Species-Asian Elephants; Social Studies: What Makes a Leader?

    ERIC Educational Resources Information Center

    Shugar, Candace; Robinson, Alice A.

    2003-01-01

    Provides six fully developed library media activities that are designed for use with specific curriculum units in creative dramatics, language arts, social studies, reading, and science. Library media skills, curriculum objectives, grade levels, resources, instructional roles, activities and procedures, evaluation, and follow-up are described for…

  12. String of Pearls: Meeting the Challenge of China’s Rising Power across the Asian Littoral

    DTIC Science & Technology

    2006-07-01

    Forecasting, July 11, 2005. 62. Seth Mydans, "New Group for Asian Century Shuns U.S.," International Herald Tribune, December 12, 2005. 63. Robert G. Sutter...Glenn Kessler , "U.S. Says China Must Address Its Intentions: How Its Power Will Be Used Is of Concern," Washington Post, September 22, 2005, p. A-16...n.p. On line. Internet, November 8, 2005. Available from www.theatlantic.com/doc/prem/2005O6Aaplan. Kessler , Glenn. "U.S. Says China Must Address Its

  13. Arms control is everyone`s business: The United States and the United Nations at the mid-point of the 1990`s

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lehman, R.F. II

    1993-03-01

    This presentation encourages current efforts in arms control, non- proliferation, and peacekeeping. Verification is heralded as a confidence building method to bring about more openness in international relations. It is purported that openness has already enhanced democratic forces around the world. The insistence on strict compliance with the decisions of the United Nations Security Council is a show of support for international law. It is recommended that international norms on human rights, non-proliferation, and non-aggression be strengthened.

  14. Road less traveled vital to operational success

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Madison, Alison L.

    2012-01-08

    PNNL's Monthly Economic Diversity column for the Tri-City Herald Business section. Excerpt follows: Things aren't always what they seem. Sometimes the path less traveled--although it can be exhausting if not scary to think about navigating its unknowns--really is the best way to go. And not just because Robert Frost said so. Patric Sazama, Regional Project Director for Impact Washington, would agree as well. He recently spoke to the Three Rivers Entrepreneur Network about achieving operational success by addressing the less tangible elements of an organization, the company's own less traveled path.

  15. Sound and heat revolutions in phononics

    NASA Astrophysics Data System (ADS)

    Maldovan, Martin

    2013-11-01

    The phonon is the physical particle representing mechanical vibration and is responsible for the transmission of everyday sound and heat. Understanding and controlling the phononic properties of materials provides opportunities to thermally insulate buildings, reduce environmental noise, transform waste heat into electricity and develop earthquake protection. Here I review recent progress and the development of new ideas and devices that make use of phononic properties to control both sound and heat. Advances in sonic and thermal diodes, optomechanical crystals, acoustic and thermal cloaking, hypersonic phononic crystals, thermoelectrics, and thermocrystals herald the next technological revolution in phononics.

  16. Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic

    PubMed Central

    Blasco, Benjamin; Leroy, Didier; Fidock, David A

    2017-01-01

    The global adoption of artemisinin-based combination therapies (ACTs) in the early 2000s heralded a new era in effectively treating drug-resistant Plasmodium falciparum malaria. However, several Southeast Asian countries have now reported the emergence of parasites that have decreased susceptibility to artemisinin (ART) derivatives and ACT partner drugs, resulting in increasing rates of treatment failures. Here we review recent advances in understanding how antimalarials act and how resistance develops, and discuss new strategies for effectively combatting resistance, optimizing treatment and advancing the global campaign to eliminate malaria. PMID:28777791

  17. [Aspects of post-tramatic stress disorder after a traffic acident].

    PubMed

    Noll-Hussong, M; Herberger, S; Grauer, M T; Otti, A; Gündel, H

    2013-09-01

    Post-traumatic stress disorder (PTSD) occurs most frequently in the general population after traffic accidents and affects up to 15 % of those involved. Mental and physical comorbidity, preliminary damage or injury can herald the development of PTSD, but the scope of social support after the accident plays a crucial role in whether and to what extent potential PTSD develops. Against this background, preventive and injury reduction aspects of the interaction between insurance companies and their customers are conceivable, which could also positively affect health economic and aspects of job or customer satisfaction.

  18. Discovery and Development of Therapeutic Drugs Against Lethal Human RNA Viruses: A Multidisciplinary Assault.

    DTIC Science & Technology

    1992-03-17

    D. F. Kefauver, G. R. Pettit, G. Groszek, M . Hollingshead, J. J. Kirsi, W. M . Shannon, E. M . Schubert, J. DaRe, B. Ugarkar, M . A. Ussery, and M . J... M . R. Boyd, J. E. Leet, C. Dufresne, D. L. Doubek, J. M . Schmidt, R. L. Cerny, J. N. A. Hooper, and K. C. Rutzler, "Isolation and Structure of the...L. Herald, N. A. Sharkey, and P. M . Blumberg, "Synthetic Conversion of Bryostatin 2 to Bryostatin 1 and Related Bryopyrans," Can. J. Chem., 69, 856

  19. Northeast Asia Regional Security and the United States Military: Context, Presence, and Roles

    DTIC Science & Technology

    2002-11-01

    27 Doug Struck, “North Korean Growth Reported,” The Washington Pos,. September 5, 2000. 28 Hae Won Choi ; “Korean Plans for Northern Détente Dented...Pressed to Halt Kumgang Tours,” The Korea Herald, March 7, 2001. 30 Hae Won Choi . Op cit. 31 Harrison, “Time to Leave Korea?” 71. 32 John Pomfret...and then went on to serve as an Assistant Professor in the Department of Social Sciences at West Point. In 2001, Major Bryant won a Council on

  20. Terrorist Criminal Pipelines and Criminalized States: Emerging Alliances

    DTIC Science & Technology

    2011-06-01

    experience, it lauds radical Islam (as well as past terrorists such as Ilich Ramírez Sánchez, better known as “Carlos the Jackal ”)35 for helping to expand...Miami Herald, November 11, 2005. 36 Ian James, “Chavez Praises Carlos the Jackal ,” Associated Press, November 21, 2009, available at <www...independent.co.uk/news/world/americas/chavez-praises-carlos-the- jackal -1825135.html>. teRRoRISt-cRIMInal PIPelIneS and cRIMInalIzed StateS 32 | FeatuReS PRISM 2, no

  1. Perspectives future space on robotics

    NASA Technical Reports Server (NTRS)

    Lavery, Dave

    1994-01-01

    Last year's flight of the German ROTEX robot flight experiment heralded the start of a new era for space robotics. ROTEX is the first of at least 10 new robotic systems and experiments that will fly before 2000. These robots will augment astronaut on-orbit capabilities and extend virtual human presence to lunar and planetary surfaces. The robotic systems to be flown in the next five years fall into three categories: extravehicular robotic (EVR) servicers, science payload servicers, and planetary surface rovers. A description of the work on these systems is presented.

  2. Entanglement detection in the vicinity of arbitrary Dicke states.

    PubMed

    Duan, L-M

    2011-10-28

    Dicke states represent a class of multipartite entangled states that can be generated experimentally with many applications in quantum information. We propose a method to experimentally detect genuine multipartite entanglement in the vicinity of arbitrary Dicke states. The detection scheme can be used to experimentally quantify the entanglement depth of many-body systems and is easy to implement as it requires measurement of only three collective spin operators. The detection criterion is strong as it heralds multipartite entanglement even in cases where the state fidelity goes down exponentially with the number of qubits.

  3. Muslims in Europe: Integration Policies in Selected Countries

    DTIC Science & Technology

    2005-11-18

    Le Monde (LM), Jan. 16, 2004, p. V. 47 Dounia Bouzar, “La Première génération de Français de confession musulman ,” in French Politics, Culture, and...Herald Tribune (IHT), April 14, 2005, p. 2. 50 Alain Boyer, “La Représentation du culte musulman en France,” p. 11-12, and Jonathan Lawrence, “From the...français du culte musulman , or CFCM). CFCM represents the Muslim religion, but is not meant to represent all Muslims in France. Rather, it is a

  4. Role of metformin in the management of polycystic ovary syndrome

    PubMed Central

    Lashen, Hany

    2010-01-01

    Polycystic ovary syndrome is the most common endocrinological disorder affecting 4–12% of women and also the most controversial. Metformin was logically introduced to establish the extent to which hyperinsulinaemia influences the pathogenesis of the condition. Early studies were very encouraging. Randomized controlled studies and several metaanalyses have changed the picture and put the drug that was once heralded as magic in a much contracted place. More work is needed to establish its right place in particular with regards to the prevention of many gestational and long-term complications. PMID:23148156

  5. [Prospects for applications in human health of nanopore-based sequencing].

    PubMed

    Audebert, Christophe; Hot, David; Caboche, Ségolène

    2018-04-01

    High throughput sequencing has opened up new clinical opportunities moving towards a medicine of precision. Oncology, infectious diseases or human genomics, many applications have been developed in recent years. The introduction of a third generation of nanopore-based sequencing technology, addressing some of the weaknesses of the previous generation, heralds a new revolution. Portability, real time, long reads and marginal investment costs, these promising new technologies point to a new shift of paradigm. What are the perspectives opened up by nanopores for clinical applications? © 2018 médecine/sciences – Inserm.

  6. Retinopathy predicts progression of fasting plasma glucose: An Early Diabetes Intervention Program (EDIP) Analysis

    PubMed Central

    Patel, Yash R.; Kirkman, M. Sue; Considine, Robert V; Hannon, Tamara S; Mather, Kieren J

    2017-01-01

    Background Retinopathy is increasingly recognized in prediabetic populations, and may herald increased risk of metabolic worsening. The Early Diabetes Intervention Program (EDIP) evaluated worsening of glycemia in screen-detected Type 2 diabetes, following participants for up to 5 years. Here we have evaluated whether the presence of retinopathy at the time of detection of diabetes was associated with accelerated progression of glycemia. Methods We prospectively studied 194 participants from EDIP with available baseline retinal photographs. Retinopathy was determined at baseline using 7-field fundus photography and defined as an Early Treatment of Diabetic Retinopathy Study Scale grading score of ≥20. Results At baseline, 12% of participants had classical retinal lesions indicating retinopathy. In univariate Cox proportional hazard analysis, the presence of retinopathy at baseline was associated with a doubled risk of progression of fasting plasma glucose (HR 2.02; 95% CI 1.05–3.89). The retinopathy effect was robust to individual adjustment for age and glucose, the most potent determinants of progression in EDIP. Conclusion Retinopathy was associated with increased risk of progression of fasting plasma glucose among adults with screen-detected, early diabetes. Early detection of retinopathy may help individualize more aggressive therapy to prevent progressive metabolic worsening in early diabetes. PMID:28003103

  7. Dark Endothelial Spots After Descemet Membrane Endothelial Keratoplasty May Appear as Recurrent Fuchs Dystrophy or Herald Graft Failure or Rejection.

    PubMed

    Zygoura, Vasiliki; Baydoun, Lamis; Monnereau, Claire; Satué, Maria; Oellerich, Silke; Melles, Gerrit R J

    2017-12-01

    To evaluate the clinical significance of dark spots in the donor endothelial cell layer as observed with specular microscopy, in patients who underwent Descemet membrane endothelial keratoplasty (DMEK) for Fuchs endothelial dystrophy (FED). Specular microscopy images of 83 consecutive eyes up to 7 years after DMEK were retrospectively reviewed in a masked fashion for the presence of dark spots and morphologic changes in the endothelial cell layer and processed for endothelial cell density (ECD) measurements. A normal endothelial cell layer was found in 52/83 eyes (62.7%) (group 0). In the remaining 31/83 eyes, various dark discolorations with or without altered endothelial cell morphology were categorized into 4 groups. Dark spots were classified as artifacts in 10/83 (12.0%) eyes (group I) and as "superimposed" dots in 10/83 (12.0%) eyes (group II), that is, optical irregularities slightly anterior to a healthy endothelial cell layer. In 11/83 (13.3%) eyes, endothelial stress was characterized by dark grayish discolorations and/or nuclear activation (group III). Most of the latter eyes also had a significant ECD decrease; 3 of these eyes later developed secondary graft failure, of which one was preceded by allograft rejection. None of the eyes showed recurrent guttae typical for FED (group IV). Dark endothelial spots after DMEK for FED may not represent a recurrent disease, but tissue irregularities just anterior to the graft. However, if associated with changes in endothelial cell morphology, nuclear activation and/or ECD decrease, dark discolorations may reflect "cellular stress" heralding secondary graft failure or (subclinical) allograft rejection.

  8. Graphing trillions of triangles

    PubMed Central

    Burkhardt, Paul

    2016-01-01

    The increasing size of Big Data is often heralded but how data are transformed and represented is also profoundly important to knowledge discovery, and this is exemplified in Big Graph analytics. Much attention has been placed on the scale of the input graph but the product of a graph algorithm can be many times larger than the input. This is true for many graph problems, such as listing all triangles in a graph. Enabling scalable graph exploration for Big Graphs requires new approaches to algorithms, architectures, and visual analytics. A brief tutorial is given to aid the argument for thoughtful representation of data in the context of graph analysis. Then a new algebraic method to reduce the arithmetic operations in counting and listing triangles in graphs is introduced. Additionally, a scalable triangle listing algorithm in the MapReduce model will be presented followed by a description of the experiments with that algorithm that led to the current largest and fastest triangle listing benchmarks to date. Finally, a method for identifying triangles in new visual graph exploration technologies is proposed. PMID:28690426

  9. Rebar Graphene

    PubMed Central

    2015-01-01

    As the cylindrical sp2-bonded carbon allotrope, carbon nanotubes (CNTs) have been widely used to reinforce bulk materials such as polymers, ceramics, and metals. However, both the concept demonstration and the fundamental understanding on how 1D CNTs reinforce atomically thin 2D layered materials, such as graphene, are still absent. Here, we demonstrate the successful synthesis of CNT-toughened graphene by simply annealing functionalized CNTs on Cu foils without needing to introduce extraneous carbon sources. The CNTs act as reinforcing bar (rebar), toughening the graphene through both π–π stacking domains and covalent bonding where the CNTs partially unzip and form a seamless 2D conjoined hybrid as revealed by aberration-corrected scanning transmission electron microscopy analysis. This is termed rebar graphene. Rebar graphene can be free-standing on water and transferred onto target substrates without needing a polymer-coating due to the rebar effects of the CNTs. The utility of rebar graphene sheets as flexible all-carbon transparent electrodes is demonstrated. The in-plane marriage of 1D nanotubes and 2D layered materials might herald an electrical and mechanical union that extends beyond carbon chemistry. PMID:24694285

  10. How will greenhouse gas observations meet changing requirements, laws, and demands?

    NASA Astrophysics Data System (ADS)

    Butler, J. H.; Tans, P. P.; Sweeney, C.; Andrews, A. E.; Miller, J. B.; Montzka, S. A.

    2010-12-01

    Recent efforts to develop a global greenhouse gas information system (GHGIS) have been driven by an anticipated need to support future national emission reduction policies or international treaties with observations. Such an effort would be similar to that done in support of the Montreal Protocol on Substances that Deplete Ozone, but more complex. However, greenhouse gas emissions are much more difficult to manage and may not be controlled by international agreement. The Kyoto Protocol has been fraught with political and practical difficulties, not the least of which is the absence of an independent observation and analysis requirement. Nevertheless, no unifying agreement was reached at the much heralded 2009 Conference of Parties (COP-15) in Copenhagen. Thus, it is quite possible (likely?) that greenhouse gas emissions may be reduced owing to other, uncoordinated policies that have their own merits, e.g., energy efficiency, alternative energy development, air quality improvement, forest development, agricultural practices, etc. If this is the future, then what observations and observation system design are needed and to what end? This presentation will discuss those needs in light of critical observations, analytical approaches, and evolving, disparate policies.

  11. Does social diversity impede sound economic management? An empirical analysis, 1980-2012.

    PubMed

    de Soysa, Indra; Vadlamannati, Krishna Chaitanya

    2017-02-01

    Several celebrated scholars argue that diverse preferences and coordination failure due to ethnic and cultural diversity hamper the social cohesion necessary for good economic management, leading to development failure. Using several measures of diversity, we find that higher levels of ethno-linguistic and cultural fractionalization are conditioned positively on higher economic growth by an index of economic freedom, which is often heralded as a good measure of sound economic management. High diversity in turn is associated with higher levels of economic freedom. We do not find any evidence to suggest that high diversity hampers change towards greater economic freedom and institutions supporting liberal policies. The effect of diversity, moreover, is conditioned positively by higher democracy. Our results raise serious doubt about the centrality of social diversity for explaining economic failure, nor is there evidence to suggest that autocratic measures are required under conditions of social diversity to implement growth-promoting policies. This is good news because history and culture seem to matter less than rational agency for ensuring sound economic management. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Small is fast: astrocytic glucose and lactate metabolism at cellular resolution

    PubMed Central

    Barros, L. F.; San Martín, A.; Sotelo-Hitschfeld, T.; Lerchundi, R.; Fernández-Moncada, I.; Ruminot, I.; Gutiérrez, R.; Valdebenito, R.; Ceballo, S.; Alegría, K.; Baeza-Lehnert, F.; Espinoza, D.

    2013-01-01

    Brain tissue is highly dynamic in terms of electrical activity and energy demand. Relevant energy metabolites have turnover times ranging from milliseconds to seconds and are rapidly exchanged between cells and within cells. Until recently these fast metabolic events were inaccessible, because standard isotopic techniques require use of populations of cells and/or involve integration times of tens of minutes. Thanks to fluorescent probes and recently available genetically-encoded optical nanosensors, this Technology Report shows how it is now possible to monitor the concentration of metabolites in real-time and in single cells. In combination with ad hoc inhibitor-stop protocols, these probes have revealed a key role for K+ in the acute stimulation of astrocytic glycolysis by synaptic activity. They have also permitted detection of the Warburg effect in single cancer cells. Genetically-encoded nanosensors currently exist for glucose, lactate, NADH and ATP, and it is envisaged that other metabolite nanosensors will soon be available. These optical tools together with improved expression systems and in vivo imaging, herald an exciting era of single-cell metabolic analysis. PMID:23526722

  13. Applications of nanotechnology in cancer.

    PubMed

    Johnson, Laura; Gunasekera, Ayanthi; Douek, Michael

    2010-04-01

    Modern cancer therapy is more individualized to specific cancer subtypes, in an attempt to treat those patients who are likely to obtain greater benefit and avoid treatment induced side effects in those who will not. Nanotechnology heralds an era whereby cancer could be diagnosed by a single agent, treated simultaneously while the diagnosis is being made, and its response to treatment monitored. Whilst nanotechnology is still mostly in the research stage, several applications are ready for translation from the bench to the bedside, in particular in the field of breast cancer. This is exciting new area of research where science fiction may become a reality.

  14. A high repetition deterministic single ion source

    NASA Astrophysics Data System (ADS)

    Sahin, C.; Geppert, P.; Müllers, A.; Ott, H.

    2017-12-01

    We report on a deterministic single ion source with high repetition rate and high fidelity. The source employs a magneto-optical trap, where ultracold rubidium atoms are photoionized. The electrons herald the creation of a corresponding ion, whose timing information is used to manipulate its trajectory in flight. We demonstrate an ion rate of up to 4× {10}4 {{{s}}}-1 and achieve a fidelity for single ion operation of 98%. The technique can be used for all atomic species, which can be laser-cooled, and opens up new applications in ion microscopy, ion implantation and surface spectroscopy.

  15. Gambling disorder in adolescents: prevalence, new developments, and treatment challenges

    PubMed Central

    Floros, Georgios D

    2018-01-01

    Research on adolescence gambling over the past twenty years has revealed significant incidence and prevalence rates and highlighted the possible negative effects on an adolescent’s well-being. Several risk and protective factors have also been identified. Over the course of the past few years, technological advances have heralded the advent of new avenues for gambling as well as new opportunities to gamble without any direct monetary exchange. This review article examines those established trends as well as the new issues that we are faced with, in order to accurately portray the current challenges in research, prevention, and treatment. PMID:29535564

  16. Prevention of extravasation injuries secondary to doxorubicin.

    PubMed

    Linder, R M; Upton, J

    1985-03-01

    Intravenously administered drugs with potentially devastating consequences should be given only by personnel highly knowledgeable regarding the side effects and skilled in intravenous cannulation. A strict protocol should be followed. The earliest signs heralding extravasation should be recognized and infusion discontinued immediately. If extravasation occurs, prompt surgical consultation is necessary. Injection into the volar wrist, dorsum of the hand, and antecubital fossa should always be avoided. Polyethylene catheters are preferable to butterfly needles for administering chemotherapeutic agents. A careful history of the venous problems of patients who require long-term therapy should be maintained in their chart. Ideally, vascular access should avoid these problems.

  17. Rocketry, film and fiction: the road to Sputnik

    NASA Astrophysics Data System (ADS)

    Brake, Mark; Hook, Neil

    2007-07-01

    The launch of Sputnik 1 in 1957 was fuelled by science fiction as well as science fact. The field of early rocketry included the work of Russians Nikolai Rynin and Konstantin Tsiolkovsky, American Robert Goddard, and German engineers Herman Oberth and Wernher Von Braun. All were directly inspired and influenced by early science fiction that heralded a space age decades ahead of time. The work of these pioneers led directly to the development of the technology needed to boost Sputnik skyward. After the launch of Sputnik, the context of the nuclear arms race opened the floodgates for a new wave of apocalyptic fiction.

  18. Syndromes associated with nutritional deficiency and excess.

    PubMed

    Jen, Melinda; Yan, Albert C

    2010-01-01

    Normal functioning of the human body requires a balance between nutritional intake and metabolism, and imbalances manifest as nutritional deficiencies or excess. Nutritional deficiency states are associated with social factors (war, poverty, famine, and food fads), medical illnesses with malabsorption (such as Crohn disease, cystic fibrosis, and after bariatric surgery), psychiatric illnesses (eating disorders, autism, alcoholism), and medications. Nutritional excess states result from inadvertent or intentional excessive intake. Cutaneous manifestations of nutritional imbalance can herald other systemic manifestations. This contribution discusses nutritional deficiency and excess syndromes with cutaneous manifestations of particular interest to clinical dermatologists. Copyright © 2010. Published by Elsevier Inc.

  19. Gambling disorder in adolescents: prevalence, new developments, and treatment challenges.

    PubMed

    Floros, Georgios D

    2018-01-01

    Research on adolescence gambling over the past twenty years has revealed significant incidence and prevalence rates and highlighted the possible negative effects on an adolescent's well-being. Several risk and protective factors have also been identified. Over the course of the past few years, technological advances have heralded the advent of new avenues for gambling as well as new opportunities to gamble without any direct monetary exchange. This review article examines those established trends as well as the new issues that we are faced with, in order to accurately portray the current challenges in research, prevention, and treatment.

  20. A high-speed tunable beam splitter for feed-forward photonic quantum information processing.

    PubMed

    Ma, Xiao-Song; Zotter, Stefan; Tetik, Nuray; Qarry, Angie; Jennewein, Thomas; Zeilinger, Anton

    2011-11-07

    We realize quantum gates for path qubits with a high-speed, polarization-independent and tunable beam splitter. Two electro-optical modulators act in a Mach-Zehnder interferometer as high-speed phase shifters and rapidly tune its splitting ratio. We test its performance with heralded single photons, observing a polarization-independent interference contrast above 95%. The switching time is about 5.6 ns, and a maximal repetition rate is 2.5 MHz. We demonstrate tunable feed-forward operations of a single-qubit gate of path-encoded qubits and a two-qubit gate via measurement-induced interaction between two photons.

  1. Subcutaneous oedema of upper limbs heralding an aggressive form of dermatomyositis.

    PubMed

    Shukla, Mohit; Patel, Rishi; Kuzyshyn, Halyna; Feinstein, David

    2018-05-30

    Subcutaneous oedema is a rare presenting clinical manifestation of dermatomyositis. In this case, we report a 44-year-old man presenting with bilateral upper extremity predominant swelling and weakness. The proximal muscle weakness, dysphagia and presence of Gottron's papules as well poikiloderma like skin changes led to the clinical diagnosis of dermatomyositis. He received aggressive treatment with high-dose glucocorticoids and required intravenous immunoglobulin with improvement in his symptoms. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  2. Big Data and Ambulatory Care

    PubMed Central

    Thorpe, Jane Hyatt; Gray, Elizabeth Alexandra

    2015-01-01

    Big data is heralded as having the potential to revolutionize health care by making large amounts of data available to support care delivery, population health, and patient engagement. Critics argue that big data's transformative potential is inhibited by privacy requirements that restrict health information exchange. However, there are a variety of permissible activities involving use and disclosure of patient information that support care delivery and management. This article presents an overview of the legal framework governing health information, dispels misconceptions about privacy regulations, and highlights how ambulatory care providers in particular can maximize the utility of big data to improve care. PMID:25401945

  3. Science in 60 – Tiny Satellites, Big Science

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sullivan, Erica

    2016-05-05

    When cube satellites first sprung on the scene in the late 1990s, they were seen as cheap, cute and novel. But today, these lunch-box-sized orbiters are heralded as powerful, cost-effective tools that help strengthen our national security presence in space. Los Alamos National Laboratory developed, built and tested CubeSats that are easily programmable from the ground, making them responsive to up-to-the-minute, mission-critical needs. While CubeSats are still the new kid on the celestial block, that’s about to change. These small, agile pieces of technology hold a universe of promise.

  4. Neutropenic Fever.

    PubMed

    White, Lindsey; Ybarra, Michael

    2017-12-01

    Fever is a common presenting complaint among adult or pediatric patients in the emergency department setting. Although fever in healthy individuals does not necessarily indicate severe illness, fever in patients with neutropenia may herald a life-threatening infection. Therefore, prompt recognition of patients with neutropenic fever is imperative. Serious bacterial illness is a significant cause of morbidity and mortality for neutropenic patients. Neutropenic fever should trigger the initiation of a rapid work-up and the administration of empiric systemic antibiotic therapy to attenuate or avoid the progression along the spectrum of sepsis, severe sepsis, septic shock syndrome, and death. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Quantum memory with optically trapped atoms.

    PubMed

    Chuu, Chih-Sung; Strassel, Thorsten; Zhao, Bo; Koch, Markus; Chen, Yu-Ao; Chen, Shuai; Yuan, Zhen-Sheng; Schmiedmayer, Jörg; Pan, Jian-Wei

    2008-09-19

    We report the experimental demonstration of quantum memory for collective atomic states in a far-detuned optical dipole trap. Generation of the collective atomic state is heralded by the detection of a Raman scattered photon and accompanied by storage in the ensemble of atoms. The optical dipole trap provides confinement for the atoms during the quantum storage while retaining the atomic coherence. We probe the quantum storage by cross correlation of the photon pair arising from the Raman scattering and the retrieval of the atomic state stored in the memory. Nonclassical correlations are observed for storage times up to 60 mus.

  6. Research District Seeing Growth

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Madison, Alison L.

    2012-05-13

    Monthly economic diversity column for the Tri-City Herald (May 2012) - excerpt follows: It’s been a while since I’ve updated you on the Tri-Cities Research District, most certainly not for lack of new activity over the past several months. In fact, much has happened, and there’s more to come. I think many of us see new land development and construction as indicative of current or impending economic growth. So those of you who have ventured into North Richland either via Stevens Drive or George Washington Way lately have probably begun sensing and anticipating that such growth is afoot.

  7. Atom-atom entanglement by single-photon detection.

    PubMed

    Slodička, L; Hétet, G; Röck, N; Schindler, P; Hennrich, M; Blatt, R

    2013-02-22

    A scheme for entangling distant atoms is realized, as proposed in the seminal paper by [C. Cabrillo et al., Phys. Rev. A 59, 1025 (1999)]. The protocol is based on quantum interference and detection of a single photon scattered from two effectively one meter distant laser cooled and trapped atomic ions. The detection of a single photon heralds entanglement of two internal states of the trapped ions with high rate and with a fidelity limited mostly by atomic motion. Control of the entangled state phase is demonstrated by changing the path length of the single-photon interferometer.

  8. Cancer-associated retinopathy with unusual retinal whitening.

    PubMed

    Lee, Joan J; Vrabec, Tamara R; Baldassano, Vincent F

    2015-01-01

    To describe the clinical characteristics and results of ocular and systemic testing in an atypical case of cancer-associated retinopathy. This study is a retrospective case report of a female patient. Rapidly progressive visual loss, vitritis, white, ring- and coin-shaped retinal lesions, and panretinal optical coherence tomography thinning preceded the diagnosis of poorly differentiated cervical carcinoma with neuroendocrine features consistent with small-cell carcinoma. Cancer-associated retinopathy can present with ring- and coin-shaped retinal lesions, vitritis, and panretinal thinning. The presence of intraocular inflammation and retinal and choroidal vasculopathy may herald more rapid visual demise.

  9. Of Soap and Seborrhea: Skin Problems in Infants

    PubMed Central

    Nickerson, Granville

    1972-01-01

    Skin lesions in infants can herald serious internal problems or be relatively benign. Interpreting skin manifestations can be extremely confusing, therefore, and although many can be ‘spot’ diagnoses, puzzling rashes should be approached systematically according to the areas that are affected and the nature of the lesions. Dr. Nickerson describes common dermatological conditions seen in the newborn and older infants and advocates a common sense approach, especially on questions of what to bathe the baby with. He outlines followup procedures for those conditions which are signs of more serious internal disorders, and emphasizes reassurance and education of the mother. PMID:20468758

  10. Who is in the Driver's Seat? Millennial-Scale Records of Wildfire in the Western USA Reveal a Complex Interplay of Climate, Fire, and Vegetation

    NASA Astrophysics Data System (ADS)

    Pierce, J. L.; Meyer, G. A.; Bigio, E.; Nelson, N.; Poulos, M. J.; Jenkins, S.; Riley, K. E.; Weppner, K.; Svenson, L.; Fitch, E. P.; Frechette, J.

    2015-12-01

    A new synthesis of 10 study areas and >480 14C dates of Holocene fire and erosional response are recorded in alluvial fan sediments of the interior western US. Chronologies are from high elevation mixed conifer forests in the N. Rockies, ponderosa and Douglas-fir forests in the N. Rockies and SW, and low elevation sagebrush steppe and piñon-juniper woodlands near the Snake River Plain. Results are as follows: 1) Late Holocene arrivals of ponderosa, lodgepole and piñon pine at Northern Rockies sites correspond with increased fire severity, linking vegetation and fire regime changes. 2) Deposit types vary with environment; sheetfloods are more common in sparsely vegetated sites and in drier Holocene periods with open forests, whereas dense forests and infrequent severe fires often produce debris flows. 3) Climate variability drives ponderosa pine and Douglas-fir forests in both the SW and N. Rockies to burn 'at both ends of the spectrum', where frequent low-severity fires are typical, but higher-severity fires burn during severe droughts following fuel buildup over wet decades. 4) Fires in dry sage steppe are generally fuel-limited, but burn during prolonged wet and variable climates; grazing, land-use, and invasive species, particularly influence modern fires. 5) At moist high-elevation lodgepole and mixed conifer sites in Yellowstone and central Idaho, episodic large debris flows indicate high severity burns, often during severe multidecadal droughts. 6) Regionally coherent peaks exist ca. 200, 500, 900, 1700 and 2600 cal yr BP, but fire activity is not generally synchronous among sites. Differences in climate among sites likely account for some asynchroneity. 7) Recent severe fires have burned in 8 of 10 sites described; erosional response appears particularly anomalous in the SW, where impacts of fire suppression and land use are greatest. Widespread and severe modern fires may herald the arrival of a no-analog era of fire in the western US.

  11. Diaphragmatic fatigue in normoxia and hyperoxia.

    PubMed

    Pardy, R L; Bye, P T

    1985-03-01

    Diaphragmatic fatigue was induced in six normal young men inspiring against a variable alinear resistance. Breathing pattern was rigidly controlled (tidal volume 0.75 liter, 12 breaths . min-1). Fatigue was defined as an inability to continue to generate a target transdiaphragmatic pressure (Pdi = 0.65 - 0.84 Pdimax). Diaphragmatic electromyogram (EMG, esophageal electrode) and perceived effort (PE, open-ended scale) were recorded. Subjects were tested on an identical resistance inspiring air or 100% O2 in random order on different days. They were unaware of the gas mixture inspired. Mean endurance time (tlim) +/- SE for air was 4.1 +/- 1.4 min and for O2 was 8.6 +/- 2.7 min (P less than 0.005). The increased tlim in O2 was associated with a delay in onset of EMG changes heralding diaphragmatic fatigue and a decrease in PE at any time during the study compared with the level of PE in air. Arterial O2 saturation (ear oximeter) remained at the resting level of 99.0 +/- 0.2% in O2 and decreased from the resting level of 97.2 +/- 0.2% by 2.8 +/- 0.7% (P less than 0.01) in air. The end-tidal CO2 fraction increased to a similar degree in air and O2 studies. We conclude that when breathing pattern, minute ventilation, and Pdi are held constant during inspiratory resistive loading, breathing O2 delays the onset of diaphragm fatigue and decreases PE.

  12. Early warning signals of regime shifts in coupled human–environment systems

    PubMed Central

    Bauch, Chris T.; Sigdel, Ram; Pharaon, Joe; Anand, Madhur

    2016-01-01

    In complex systems, a critical transition is a shift in a system’s dynamical regime from its current state to a strongly contrasting state as external conditions move beyond a tipping point. These transitions are often preceded by characteristic early warning signals such as increased system variability. However, early warning signals in complex, coupled human–environment systems (HESs) remain little studied. Here, we compare critical transitions and their early warning signals in a coupled HES model to an equivalent environment model uncoupled from the human system. We parameterize the HES model, using social and ecological data from old-growth forests in Oregon. We find that the coupled HES exhibits a richer variety of dynamics and regime shifts than the uncoupled environment system. Moreover, the early warning signals in the coupled HES can be ambiguous, heralding either an era of ecosystem conservationism or collapse of both forest ecosystems and conservationism. The presence of human feedback in the coupled HES can also mitigate the early warning signal, making it more difficult to detect the oncoming regime shift. We furthermore show how the coupled HES can be “doomed to criticality”: Strategic human interactions cause the system to remain perpetually in the vicinity of a collapse threshold, as humans become complacent when the resource seems protected but respond rapidly when it is under immediate threat. We conclude that the opportunities, benefits, and challenges of modeling regime shifts and early warning signals in coupled HESs merit further research. PMID:27815533

  13. Post-glacial flooding of the Bering Land Bridge dated to 11 cal ka BP based on new geophysical and sediment records

    USGS Publications Warehouse

    Jakobsson, Martin; Pearce, Christof; Cronin, Thomas M.; Backman, Jan; Anderson, Leif G.; Barrientos, Natalia; Bjork, Goran; Coxhall, Helen; de Boer, Agatha; Mayer, Larry; Morth, Carl-Magnus; Nilsson, Johan; Rattray, Jayne; Sranne, Christian; Semiletov, Igor; O'Regan, Matt

    2017-01-01

    The Bering Strait connects the Arctic and Pacific oceans and separates the North American and Asian landmasses. The presently shallow ( ∼  53 m) strait was exposed during the sea level lowstand of the last glacial period, which permitted human migration across a land bridge today referred to as the Bering Land Bridge. Proxy studies (stable isotope composition of foraminifera, whale migration into the Arctic Ocean, mollusc and insect fossils and paleobotanical data) have suggested a range of ages for the Bering Strait reopening, mainly falling within the Younger Dryas stadial (12.9–11.7 cal ka BP). Here we provide new information on the deglacial and post-glacial evolution of the Arctic–Pacific connection through the Bering Strait based on analyses of geological and geophysical data from Herald Canyon, located north of the Bering Strait on the Chukchi Sea shelf region in the western Arctic Ocean. Our results suggest an initial opening at about 11 cal ka BP in the earliest Holocene, which is later than in several previous studies. Our key evidence is based on a well-dated core from Herald Canyon, in which a shift from a near-shore environment to a Pacific-influenced open marine setting at around 11 cal ka BP is observed. The shift corresponds to meltwater pulse 1b (MWP1b) and is interpreted to signify relatively rapid breaching of the Bering Strait and the submergence of the large Bering Land Bridge. Although the precise rates of sea level rise cannot be quantified, our new results suggest that the late deglacial sea level rise was rapid and occurred after the end of the Younger Dryas stadial.

  14. Post-glacial flooding of the Bering Land Bridge dated to 11 cal ka BP based on new geophysical and sediment records

    NASA Astrophysics Data System (ADS)

    Jakobsson, Martin; Pearce, Christof; Cronin, Thomas M.; Backman, Jan; Anderson, Leif G.; Barrientos, Natalia; Björk, Göran; Coxall, Helen; de Boer, Agatha; Mayer, Larry A.; Mörth, Carl-Magnus; Nilsson, Johan; Rattray, Jayne E.; Stranne, Christian; Semiletov, Igor; O'Regan, Matt

    2017-08-01

    The Bering Strait connects the Arctic and Pacific oceans and separates the North American and Asian landmasses. The presently shallow ( ˜ 53 m) strait was exposed during the sea level lowstand of the last glacial period, which permitted human migration across a land bridge today referred to as the Bering Land Bridge. Proxy studies (stable isotope composition of foraminifera, whale migration into the Arctic Ocean, mollusc and insect fossils and paleobotanical data) have suggested a range of ages for the Bering Strait reopening, mainly falling within the Younger Dryas stadial (12.9-11.7 cal ka BP). Here we provide new information on the deglacial and post-glacial evolution of the Arctic-Pacific connection through the Bering Strait based on analyses of geological and geophysical data from Herald Canyon, located north of the Bering Strait on the Chukchi Sea shelf region in the western Arctic Ocean. Our results suggest an initial opening at about 11 cal ka BP in the earliest Holocene, which is later than in several previous studies. Our key evidence is based on a well-dated core from Herald Canyon, in which a shift from a near-shore environment to a Pacific-influenced open marine setting at around 11 cal ka BP is observed. The shift corresponds to meltwater pulse 1b (MWP1b) and is interpreted to signify relatively rapid breaching of the Bering Strait and the submergence of the large Bering Land Bridge. Although the precise rates of sea level rise cannot be quantified, our new results suggest that the late deglacial sea level rise was rapid and occurred after the end of the Younger Dryas stadial.

  15. Implementation of an acoustic-based methane flux estimation methodology in the Eastern Siberian Arctic Sea

    NASA Astrophysics Data System (ADS)

    Weidner, E. F.; Weber, T. C.; Mayer, L. A.

    2017-12-01

    Quantifying methane flux originating from marine seep systems in climatically sensitive regions is of critically importance for current and future climate studies. Yet, the methane contribution from these systems has been difficult to estimate given the broad spatial scale of the ocean and the heterogeneity of seep activity. One such region is the Eastern Siberian Arctic Sea (ESAS), where bubble release into the shallow water column (<40 meters average depth) facilitates transport of methane to the atmosphere without oxidation. Quantifying the current seep methane flux from the ESAS is necessary to understand not only the total ocean methane budget, but also to provide baseline estimates against which future climate-induced changes can be measured. At the 2016 AGU fall meeting, we presented a new acoustic-based flux methodology using a calibrated broadband split-beam echosounder. The broad (14-24 kHz) bandwidth provides a vertical resolution of 10 cm, making possible the identification of single bubbles. After calibration using 64 mm copper sphere of known backscatter, the acoustic backscatter of individual bubbles is measured and compared to analytical models to estimate bubble radius. Additionally, bubbles are precisely located and traced upwards through the water column to estimate rise velocity. The combination of radius and rise velocity allows for gas flux estimation. Here, we follow up with the completed implementation of this methodology applied to the Herald Canyon region of the western ESAS. From the 68 recognized seeps, bubble radii and rise velocity were computed for more than 550 individual bubbles. The range of bubble radii, 1-6 mm, is comparable to those published by other investigators, while the radius dependent rise velocities are consistent with published models. Methane flux for the Herald Canyon region was estimated by extrapolation from individual seep flux values.

  16. Few-Photon Nonlinearity with an Atomic Ensemble in an Optical Cavity

    NASA Astrophysics Data System (ADS)

    Tanji, Haruka

    2011-12-01

    This thesis investigates the effect of the cavity vacuum field on the dispersive properties of an atomic ensemble in a strongly coupled high-finesse cavity. In particular, we demonstrate vacuum-induced transparency (VIT). The light absorption by the ensemble is suppressed by up to 40% in the presence of a cavity vacuum field. The sharp transparency peak is accompanied by the reduction in the group velocity of a light pulse, measured to be as low as 1800 m/s. This observation is a large step towards the realization of photon number-state filters, recently proposed by Nikoghosyan et al. Furthermore, we demonstrate few-photon optical nonlinearity, where the transparency is increased from 40% to 80% with ˜12 photons in the cavity mode. The result may be viewed as all-optical switching, where the transmission of photons in one mode may be controlled by 12 photons in another. These studies point to the possibility of nonlinear interaction between photons in different free-space modes, a scheme that circumvents cavity-coupling losses that plague cavity-based quantum information processing. Potential applications include advanced quantum devices such as photonic quantum gates, photon-number resolving detectors, and single-photon transistors. In the efforts leading up to these results, we investigate the collective enhancement of atomic coupling to a single mode of a low-finesse cavity. With the strong collective coupling, we obtain exquisite control of quantum states in the atom-photon coupled system. In this system, we demonstrate a heralded single-photon source with 84% conditional efficiency, a quantum bus for deterministic entanglement of two remote ensembles, and heralded polarization-state quantum memory with fidelity above 90%.

  17. Raman analysis of complex pigment mixtures in 20th century metal knight shields of the Order of the Elephant.

    PubMed

    Lauridsen, Clara Bratt; Sanyova, Jana; Simonsen, Kim Pilkjær

    2015-11-05

    The pigment composition of six painted metal knight shields of the Order of the Elephant dating from the second half of the 20th century belonging to the Danish royal collection were studied using Raman microscopy. By focusing a 785 nm laser with a 50× objective on particles in paint cross sections, it was possible to identify the following 20 compounds: hematite, goethite, chrome red/orange, chrome yellow, zinc chrome yellow, carbon black, toluidine red PR3, chlorinated para red PR4, dinitroaniline orange PO5, phthalocyanine blue PB15, indanthrone blue PB60, ultramarine, Prussian blue, lead white, anatase, rutile, calcium carbonate, barium sulphate, gypsum and dolomite. The components were frequently present in complex pigment mixtures. Additional information was obtained by elemental analysis with scanning electron microscopy-energy dispersive X-ray spectroscopy (SEM-EDX) to identify cobalt blue, zinc white and cadmium red, as well as to indicate the presence of zinc white in some pigment mixtures. The study allowed a comparison between the industrially applied preparation layers and the artistic paint layers applied by the heraldic painter. Differences in the choice of paint and pigment types were observed on the earliest knight shields, demonstrating a general delay of industrial materials into artist paints. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Development of upper tract stones in patients with congenital neurogenic bladder.

    PubMed

    Stephany, Heidi A; Clayton, Douglass B; Tanaka, Stacy T; Thomas, John C; Pope, John C; Brock, John W; Adams, Mark C

    2014-02-01

    Patients with neurogenic bladder are at increased risk of developing upper tract stones. We hypothesized that patients with lower urinary tract stone disease are at greater risk of developing upper tract stones. We performed a 10-year retrospective case-control study of patients with neurogenic bladder to determine the association between bladder and upper tract stones. Independent risk factors for upper tract stones were assessed. Cases and controls were matched 1:1. Univariable analysis was performed by Fisher's exact test and the Mann-Whitney U test. Multivariable logistic regression was performed. 52 cases and controls were identified. Cases were significantly more likely to be non-ambulatory, have bowel-urinary tract interposition, thoracic level dysraphism, and history of bladder stones. On multivariable analysis, independent predictors of stone formation were male sex (OR 2.82; p = 0.02), dysraphism involving the thoracic spine (OR 3.37; p = 0.014) bowel-urinary tract interposition (OR 2.611; p = 0.038), and a history of bladder stones (OR 3.57; p = 0.015). Patients with neurogenic bladder are at increased risk for upper tract stones. The presence of bladder stones may herald the development of upper tract stones. The predictors of stone disease identified should guide prospective studies to better understand the natural history of upper tract stone development in this population. Copyright © 2013 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

  19. A silk purse from a sow's ear-bioinspired materials based on α-helical coiled coils.

    PubMed

    Quinlan, Roy A; Bromley, Elizabeth H; Pohl, Ehmke

    2015-02-01

    This past few years have heralded remarkable times for intermediate filaments with new revelations of their structural properties that has included the first crystallographic-based model of vimentin to build on the experimental data of intra-filament interactions determined by chemical cross-linking. Now with these and other advances on their assembly, their biomechanical and their cell biological properties outlined in this review, the exploitation of the biomechanical and structural properties of intermediate filaments, their nanocomposites and biomimetic derivatives in the biomedical and private sectors has started. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  20. Basic principles of cone beam computed tomography.

    PubMed

    Abramovitch, Kenneth; Rice, Dwight D

    2014-07-01

    At the end of the millennium, cone-beam computed tomography (CBCT) heralded a new dental technology for the next century. Owing to the dramatic and positive impact of CBCT on implant dentistry and orthognathic/orthodontic patient care, additional applications for this technology soon evolved. New software programs were developed to improve the applicability of, and access to, CBCT for dental patients. Improved, rapid, and cost-effective computer technology, combined with the ability of software engineers to develop multiple dental imaging applications for CBCT with broad diagnostic capability, have played a large part in the rapid incorporation of CBCT technology into dentistry. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Minimally Invasive Surgery (MIS) Approaches to Thoracolumbar Trauma.

    PubMed

    Kaye, Ian David; Passias, Peter

    2018-03-01

    Minimally invasive surgical (MIS) techniques offer promising improvements in the management of thoracolumbar trauma. Recent advances in MIS techniques and instrumentation for degenerative conditions have heralded a growing interest in employing these techniques for thoracolumbar trauma. Specifically, surgeons have applied these techniques to help manage flexion- and extension-distraction injuries, neurologically intact burst fractures, and cases of damage control. Minimally invasive surgical techniques offer a means to decrease blood loss, shorten operative time, reduce infection risk, and shorten hospital stays. Herein, we review thoracolumbar minimally invasive surgery with an emphasis on thoracolumbar trauma classification, minimally invasive spinal stabilization, surgical indications, patient outcomes, technical considerations, and potential complications.

  2. Compensation issues tough to navigate

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Madison, Alison L.

    2012-02-12

    Monthly economic diversity column for the Tri-City Herald - excerpt pasted below: Most industries out there are feeling the shift to a more educated, thus more empowered consumer. The legal field is no exception, which is why it's no surprise that lawsuits are on the rise. Today's society is one in which people are more aware than ever of their rights, and often equally convinced of their entitlements in a number of areas. For business owners, employees represent a major source of potential lawsuits. And compensation is an area of particular concern given that many complaints against employers revolve aroundmore » it in some way.« less

  3. Incomplete Detection of Nonclassical Phase-Space Distributions

    NASA Astrophysics Data System (ADS)

    Bohmann, M.; Tiedau, J.; Bartley, T.; Sperling, J.; Silberhorn, C.; Vogel, W.

    2018-02-01

    We implement the direct sampling of negative phase-space functions via unbalanced homodyne measurement using click-counting detectors. The negativities significantly certify nonclassical light in the high-loss regime using a small number of detectors which cannot resolve individual photons. We apply our method to heralded single-photon states and experimentally demonstrate the most significant certification of nonclassicality for only two detection bins. By contrast, the frequently applied Wigner function fails to directly indicate such quantum characteristics for the quantum efficiencies present in our setup without applying additional reconstruction algorithms. Therefore, we realize a robust and reliable approach to characterize nonclassical light in phase space under realistic conditions.

  4. Quantum teleportation between distant matter qubits.

    PubMed

    Olmschenk, S; Matsukevich, D N; Maunz, P; Hayes, D; Duan, L-M; Monroe, C

    2009-01-23

    Quantum teleportation is the faithful transfer of quantum states between systems, relying on the prior establishment of entanglement and using only classical communication during the transmission. We report teleportation of quantum information between atomic quantum memories separated by about 1 meter. A quantum bit stored in a single trapped ytterbium ion (Yb+) is teleported to a second Yb+ atom with an average fidelity of 90% over a replete set of states. The teleportation protocol is based on the heralded entanglement of the atoms through interference and detection of photons emitted from each atom and guided through optical fibers. This scheme may be used for scalable quantum computation and quantum communication.

  5. Probabilistic metrology or how some measurement outcomes render ultra-precise estimates

    NASA Astrophysics Data System (ADS)

    Calsamiglia, J.; Gendra, B.; Muñoz-Tapia, R.; Bagan, E.

    2016-10-01

    We show on theoretical grounds that, even in the presence of noise, probabilistic measurement strategies (which have a certain probability of failure or abstention) can provide, upon a heralded successful outcome, estimates with a precision that exceeds the deterministic bounds for the average precision. This establishes a new ultimate bound on the phase estimation precision of particular measurement outcomes (or sequence of outcomes). For probe systems subject to local dephasing, we quantify such precision limit as a function of the probability of failure that can be tolerated. Our results show that the possibility of abstaining can set back the detrimental effects of noise.

  6. KSC-69PC-0397

    NASA Image and Video Library

    1969-07-16

    CAPE CANAVERAL, Fla. -- The American Flag heralds the flight of Apollo 11, man's first lunar landing mission. This double exposure was made with a 1,000 mm lens. The photograph was taken from Cape Kennedy, adjacent to Kennedy Space Center, where Apollo 11 lifted off from pad 39A at 9:32 a.m. EDT. This image was imposed upon the image of hte flag, filmed a day earlier. In the photo, the rocket at an alititude of about 5,000 feet. A band of super-cold propellants seems to circle the rocket near its center. The effect is caused by the difference in temperature between the propellants and the atmosphere. Photo credit: NASA

  7. Epstein-Barr viral load assessment in immunocompetent patients with fulminant infectious mononucleosis.

    PubMed

    van Laar, Jan A M; Buysse, Corinne M P; Vossen, Ann C T M; Hjálmarsson, Björn; van Den Berg, Bart; van Lom, Kirsten; Deinum, Jaap

    2002-04-08

    We describe 2 immunocompetent adolescents with fulminant infectious mononucleosis and virus-associated hemophagocytosis. A new quantitative polymerase chain reaction revealed high serum Epstein-Barr virus DNA levels in these patients. One patient died with an increasing viral load not responding to corticosteroids followed by antiviral and intensified immunomodulatory treatment. The other patient received corticosteroids and acyclovir at diagnosis; her rapid recovery was heralded by a steep decline of viral load. We propose monitoring the clinical course of fulminant infectious mononucleosis in immunocompetent patients by Epstein-Barr virus DNA quantification and prompt corticosteroid and antiviral therapy when viral load is high.

  8. Transformational leadership: a cascading chain reaction.

    PubMed

    Murphy, Lorraine

    2005-03-01

    Historical influences still permeate contemporary nursing practise. These are mirrored in organizational philosophies, transactional and autocratic leadership styles and disempowered staff. Whilst there is disparity amongst the theorists' definitions of leadership, there is consensus pertaining to the attributes necessary to realize effective leadership. Transformational leadership is heralded as new criterion for nurse managers, and can be achieved through training, education and professional development in key leadership competencies. To achieve a chain reaction, charismatic transformational leaders espouse intellectual stimulation and individual consideration to empower staff and enhance patient care. Nurse managers that develop and foster transformational leadership can surmount oppressive traditions and confidently navigate a complex and rapidly changing health care environment.

  9. Experimental entanglement of 25 individually accessible atomic quantum interfaces.

    PubMed

    Pu, Yunfei; Wu, Yukai; Jiang, Nan; Chang, Wei; Li, Chang; Zhang, Sheng; Duan, Luming

    2018-04-01

    A quantum interface links the stationary qubits in a quantum memory with flying photonic qubits in optical transmission channels and constitutes a critical element for the future quantum internet. Entanglement of quantum interfaces is an important step for the realization of quantum networks. Through heralded detection of photon interference, we generate multipartite entanglement between 25 (or 9) individually addressable quantum interfaces in a multiplexed atomic quantum memory array and confirm genuine 22-partite (or 9-partite) entanglement. This experimental entanglement of a record-high number of individually addressable quantum interfaces makes an important step toward the realization of quantum networks, long-distance quantum communication, and multipartite quantum information processing.

  10. Lessons learned from modern military surgery.

    PubMed

    Beekley, Alec C; Starnes, Benjamin W; Sebesta, James A

    2007-02-01

    The era of global terrorism and asymmetric warfare heralded by the September 11, 2001 attacks on the United States have blurred the traditional lines between civilian and military trauma. The lessons learned by physicians in the theaters of war, particularly regarding the response to mass casualties, blast and fragmentation injuries, and resuscitation of casualties in austere environments, likely resonate strongly with civilian trauma surgeons in the current era. The evolution of a streamlined trauma system in the theaters of operations, the introduction of an in-theater institution review board process, and dedicated personnel to collect combat casualty data have resulted in improved data capture and realtime, on-the-scene research.

  11. Open Labware: 3-D Printing Your Own Lab Equipment

    PubMed Central

    Baden, Tom; Chagas, Andre Maia; Gage, Greg; Marzullo, Timothy; Prieto-Godino, Lucia L.; Euler, Thomas

    2015-01-01

    The introduction of affordable, consumer-oriented 3-D printers is a milestone in the current “maker movement,” which has been heralded as the next industrial revolution. Combined with free and open sharing of detailed design blueprints and accessible development tools, rapid prototypes of complex products can now be assembled in one’s own garage—a game-changer reminiscent of the early days of personal computing. At the same time, 3-D printing has also allowed the scientific and engineering community to build the “little things” that help a lab get up and running much faster and easier than ever before. PMID:25794301

  12. Science in 60 – Tiny Satellites, Big Science

    ScienceCinema

    Sullivan, Erica

    2018-05-31

    When cube satellites first sprung on the scene in the late 1990s, they were seen as cheap, cute and novel. But today, these lunch-box-sized orbiters are heralded as powerful, cost-effective tools that help strengthen our national security presence in space. Los Alamos National Laboratory developed, built and tested CubeSats that are easily programmable from the ground, making them responsive to up-to-the-minute, mission-critical needs. While CubeSats are still the new kid on the celestial block, that’s about to change. These small, agile pieces of technology hold a universe of promise.

  13. Entanglement distribution schemes employing coherent photon-to-spin conversion in semiconductor quantum dot circuits

    NASA Astrophysics Data System (ADS)

    Gaudreau, Louis; Bogan, Alex; Korkusinski, Marek; Studenikin, Sergei; Austing, D. Guy; Sachrajda, Andrew S.

    2017-09-01

    Long distance entanglement distribution is an important problem for quantum information technologies to solve. Current optical schemes are known to have fundamental limitations. A coherent photon-to-spin interface built with quantum dots (QDs) in a direct bandgap semiconductor can provide a solution for efficient entanglement distribution. QD circuits offer integrated spin processing for full Bell state measurement (BSM) analysis and spin quantum memory. Crucially the photo-generated spins can be heralded by non-destructive charge detection techniques. We review current schemes to transfer a polarization-encoded state or a time-bin-encoded state of a photon to the state of a spin in a QD. The spin may be that of an electron or that of a hole. We describe adaptations of the original schemes to employ heavy holes which have a number of attractive properties including a g-factor that is tunable to zero for QDs in an appropriately oriented external magnetic field. We also introduce simple throughput scaling models to demonstrate the potential performance advantage of full BSM capability in a QD scheme, even when the quantum memory is imperfect, over optical schemes relying on linear optical elements and ensemble quantum memories.

  14. Genetic control of postnatal human brain growth

    PubMed Central

    van Dyck, Laura I.; Morrow, Eric M.

    2017-01-01

    Purpose of review Studies investigating postnatal brain growth disorders inform the biology underlying the development of human brain circuitry. This research is becoming increasingly important for the diagnosis and treatment of childhood neurodevelopmental disorders, including autism and related disorders. Here we review recent research on typical and abnormal postnatal brain growth and examine potential biological mechanisms. Recent findings Clinically, brain growth disorders are heralded by diverging head size for a given age and sex, but are more precisely characterized by brain imaging, postmortem analysis, and animal model studies. Recent neuroimaging and molecular biological studies on postnatal brain growth disorders have broadened our view of both typical and pathological postnatal neurodevelopment. Correlating gene and protein function with brain growth trajectories uncovers postnatal biological mechanisms, including neuronal arborization, synaptogenesis and pruning, and gliogenesis and myelination. Recent investigations of childhood neurodevelopmental and neurodegenerative disorders highlight the underlying genetic programming and experience-dependent remodeling of neural circuitry. Summary In order to understand typical and abnormal postnatal brain development, clinicians and researchers should characterize brain growth trajectories in the context of neurogenetic syndromes. Understanding mechanisms and trajectories of postnatal brain growth will aid in differentiating, diagnosing, and potentially treating neurodevelopmental disorders. PMID:27898583

  15. Methodological quality of randomised controlled trials in burns care. A systematic review.

    PubMed

    Danilla, Stefan; Wasiak, Jason; Searle, Susana; Arriagada, Cristian; Pedreros, Cesar; Cleland, Heather; Spinks, Anneliese

    2009-11-01

    To evaluate the methodological quality of published randomised controlled trials (RCTs) in burn care treatment and management. Using a predetermined search strategy we searched Ovid MEDLINE (1950 to January 2008) database to identify all English RCTs related to burn care. Full text studies identified were reviewed for key demographic and methodological characteristics. Methodological trial quality was assessed using the Jadad scale. A total of 257 studies involving 14,535 patients met the inclusion criteria. The median Jadad score was 2 (out of a best possible score of 5). Information was given in the introduction and discussion sections of most RCTs, although insufficient detail was provided on randomisation, allocation concealment, and blinding. The number of RCTs increased between 1950 and 2008 (Spearman's rho=0.6129, P<0.001), although the reporting quality did not improve over the same time period (P=0.1896) and was better in RCTs with larger sample sizes (median Jadad score, 4 vs. 2 points, P<0.0001). Methodological quality did not correlate with journal impact factor (P=0.2371). The reporting standards of RCTs are highly variable and less than optimal in most cases. The advent of evidence-based medicine heralds a new approach to burns care and systematic steps are needed to improve the quality of RCTs in this field. Identifying and reviewing the existing number of RCTs not only highlights the need for burn clinicians to conduct more trials, but may also encourage burn health clinicians to consider the importance of conducting trials that follow appropriate, evidence-based standards.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Madison, Alison L.

    November Economic Diversity column for the Tri-City Herald - Topic: Social Purpose Corporations - Excerpt below: On March 31, Governor Chris Gregoire made history when she signed HB2239 and created Washington’s first alternative for-profit corporate structure, the social purpose corporation, or SPC. The new structure allows for-profit entities to formally strive toward creation of social and environmental good as their top corporate priority. This significantly contrasts with the expectation that traditional companies must put creation of shareholder value first. It signals that Washington State believes corporate leadership should have the flexibility and legal backing to make decisions based on themore » company’s impact on all of its stakeholders rather than on the ability to maximize profits.« less

  17. Immunologic Approaches for the Treatment of Multiple Myeloma

    PubMed Central

    Rasche, Leo; Weinhold, Niels; Morgan, Gareth J; van Rhee, Frits; Davies, Faith E

    2017-01-01

    The FDA approval of two monoclonal antibodies in 2015 has heralded a new era of targeted immunotherapies for multiple myeloma (MM). In this review we discuss the recent approaches using different immunological components to treat MM. In particular, we review current monoclonal antibody based therapies, engineered T- and NK cell products, ‘off-target’ immunomodulation, and strategies utilizing allogeneic cell transplantation in MM. We discuss how an immunologic approach offers promise for the treatment of this genetically heterogeneous disease, and how patients with acquired drug resistance may particularly benefit from these therapies. We also describe some of the limitations of the current strategies and speculate on the future of personalized immunotherapies for MM. PMID:28431262

  18. New developments in ancient genomics.

    PubMed

    Millar, Craig D; Huynen, Leon; Subramanian, Sankar; Mohandesan, Elmira; Lambert, David M

    2008-07-01

    Ancient DNA research is on the crest of a 'third wave' of progress due to the introduction of a new generation of DNA sequencing technologies. Here we review the advantages and disadvantages of the four new DNA sequencers that are becoming available to researchers. These machines now allow the recovery of orders of magnitude more DNA sequence data, albeit as short sequence reads. Hence, the potential reassembly of complete ancient genomes seems imminent, and when used to screen libraries of ancient sequences, these methods are cost effective. This new wealth of data is also likely to herald investigations into the functional properties of extinct genes and gene complexes and will improve our understanding of the biological basis of extinct phenotypes.

  19. History and Technical Approaches and Considerations for Ablative Surgery for Epilepsy.

    PubMed

    Sinha, Saurabh; Danish, Shabbar F

    2016-01-01

    The history of epilepsy surgery is generally noted to have begun in 1886 with Victor Horsley's first report of craniotomies for posttraumatic epilepsy. With increased understanding of brain function and development of electroencephalographic methods, nonlesional epilepsy began to be treated with resection in the 1950s. Methodological improvements and increased understanding of pathophysiology followed, and the advent of stereotaxy and ablative technology in the 1960s and 1970s heralded a new era of minimally invasive, targeted procedures for lesional and nonlesional epilepsy. Current techniques combine stereotactic methods, improved ablative technologies, and electroencephalographic methods for a multidisciplinary approach to the neurosurgical treatment of epilepsy. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Cost containment: challenging fidelity and justice.

    PubMed

    Haavi Morreim, E

    1988-12-01

    Cost containment heralds a general tightening of health care funds, which subjects every health care intervention to scrutiny for its economic as well as its medical wisdom and imposes upon physicians a variety of controls and incentives. Fiduciary fidelity is challenged by the conflict between clinical authority and patient loyalty, by financial and professional incentives that pit the physician's own interests against those of his or her patients, by the stratification of resources which results in greater scarcity of funds for indigent care, and by standardization of care through the implementation of "efficiency protocols." Questions of clinical justice are analyzed in the areas of distribution of medical services and of contractual relations among patient, payer, physician, and institution.

  1. Studying the lower limit of human vision with a single-photon source

    NASA Astrophysics Data System (ADS)

    Holmes, Rebecca; Christensen, Bradley; Street, Whitney; Wang, Ranxiao; Kwiat, Paul

    2015-05-01

    Humans can detect a visual stimulus of just a few photons. Exactly how few is not known--psychological and physiological research have suggested that the detection threshold may be as low as one photon, but the question has never been directly tested. Using a source of heralded single photons based on spontaneous parametric downconversion, we can directly characterize the lower limit of vision. This system can also be used to study temporal and spatial integration in the visual system, and to study visual attention with EEG. We may eventually even be able to investigate how human observers perceive quantum effects such as superposition and entanglement. Our progress and some preliminary results will be discussed.

  2. Instrumental Aid by Japanese Official Development Assistance for Astronomy in Developing Countries

    NASA Astrophysics Data System (ADS)

    Kitamura, Masatoshi

    In order to promote education and research in developing countries, the Japanese Government has been providing developing countries with high-grade equipment under the framework of the Official Development Assistance (ODA) cooperation programme since 1982. Under this successful cooperation programme, 24 astronomical instruments have been donated to 19 developing countries up to the end of the Japanese fiscal year 2003. The instruments donated included university-level reflecting telescopes, as well as modern planetaria used for educational purposes, together with various accessories. This paper describes a continuation of the previous ODA donations (Astronomical Herald 1997) and the subsequent follow-up programmes provided with the assistance of Japan International Cooperation Agency (JICA).

  3. The case for renewed investment in the district nursing specialist practitioner qualification.

    PubMed

    Longstaff, Fiona

    2013-09-01

    District nursing as a profession has been under significant threat over the last few years due to a lack of foresight and funding, resulting in an undervalued and underinvested workforce. The once-heralded specialist practitioner programme was slowly decommissioned in all but a handful of universities, leaving no alternative but for community trusts to employ staff nurses in team leader roles without the development the added qualification gave them. In light of the renewed focus on the fundamental advancement of district nurses and recent Government publications clearly reinforcing the district nurse's role, this article argues for the need for educational commissioners and workforce planners to commit to continued investment in this vital profession.

  4. Photon pair generation with tailored frequency correlations in graded-index multimode fibers.

    PubMed

    Pourbeyram, Hamed; Mafi, Arash

    2018-05-01

    We study theoretically the generation of photon pairs with controlled spectral correlations via the four-wave mixing process in graded-index multimode optical fibers (GIMFs). We show that the quantum correlations of the generated photons in GIMFs can be preserved over a wide spectral range for a tunable pump source. Therefore, GIMFs can be utilized as quantum-state-preserving tunable sources of photons. In particular, we have shown that it is possible to generate factorable two-photon states, which allow for heralding of pure-state single photons without the need for narrowband spectral post filtering. We also elaborate on the possibility of simultaneously generating correlated and uncorrelated photon pairs in the same optical fiber.

  5. Proteome-scale human interactomics

    PubMed Central

    Luck, Katja; Sheynkman, Gloria M.; Zhang, Ivy; Vidal, Marc

    2017-01-01

    Cellular functions are mediated by complex interactome networks of physical, biochemical, and functional interactions between DNA sequences, RNA molecules, proteins, lipids, and small metabolites. A thorough understanding of cellular organization requires accurate and relatively complete models of interactome networks at proteome-scale. The recent publication of four human protein-protein interaction (PPI) maps represents a technological breakthrough and an unprecedented resource for the scientific community, heralding a new era of proteome-scale human interactomics. Our knowledge gained from these and complementary studies provides fresh insights into the opportunities and challenges when analyzing systematically generated interactome data, defines a clear roadmap towards the generation of a first reference interactome, and reveals new perspectives on the organization of cellular life. PMID:28284537

  6. Early relapse of Burkitt lymphoma heralded by a bone marrow necrosis and numb chin syndrome successfully treated with allogeneic stem cell transplantation

    PubMed Central

    Cerny, Jan; Devitt, Katherine; Yu, Hongbo; Ramanathan, Muthalagu; Woda, Bruce; Nath, Rajneesh

    2014-01-01

    The optimal salvage therapy for patients with relapsed Burkitt lymphoma is unknown. Bone marrow necrosis is an underreported (<1% of bone marrow failures). Numb chin syndrome is another rare syndrome associated with aggressive malignancies. Survival of these syndromes is dictated by the underlying disease and is usually dismal. Our 35-year-old patient experienced an early relapse of Burkitt lymphoma accompanied by syndromes, achieved second complete remission and underwent allogeneic stem cell transplantation. He remains alive and well >2 years after the transplant. To our knowledge, this is the longest reported survival of the two syndromes in the setting of BL relapse. PMID:25068102

  7. Early relapse of Burkitt lymphoma heralded by a bone marrow necrosis and numb chin syndrome successfully treated with allogeneic stem cell transplantation.

    PubMed

    Cerny, Jan; Devitt, Katherine; Yu, Hongbo; Ramanathan, Muthalagu; Woda, Bruce; Nath, Rajneesh

    2014-01-01

    The optimal salvage therapy for patients with relapsed Burkitt lymphoma is unknown. Bone marrow necrosis is an underreported (<1% of bone marrow failures). Numb chin syndrome is another rare syndrome associated with aggressive malignancies. Survival of these syndromes is dictated by the underlying disease and is usually dismal. Our 35-year-old patient experienced an early relapse of Burkitt lymphoma accompanied by syndromes, achieved second complete remission and underwent allogeneic stem cell transplantation. He remains alive and well >2 years after the transplant. To our knowledge, this is the longest reported survival of the two syndromes in the setting of BL relapse.

  8. The formation and fragmentation of disks around primordial protostars.

    PubMed

    Clark, Paul C; Glover, Simon C O; Smith, Rowan J; Greif, Thomas H; Klessen, Ralf S; Bromm, Volker

    2011-02-25

    The very first stars to form in the universe heralded an end to the cosmic dark ages and introduced new physical processes that shaped early cosmic evolution. Until now, it was thought that these stars lived short, solitary lives, with only one extremely massive star, or possibly a very wide binary system, forming in each dark-matter minihalo. Here we describe numerical simulations that show that these stars were, to the contrary, often members of tight multiple systems. Our results show that the disks that formed around the first young stars were unstable to gravitational fragmentation, possibly producing small binary and higher-order systems that had separations as small as the distance between Earth and the Sun.

  9. Recruiting as much about families as candidate

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Madison, Alison L.

    2011-06-05

    Monthly economic diversity column for Tri-City Herald: For businesses large and small, one of the biggest challenges to staying afloat and achieving growth is attracting and retaining key talent. And in an area such as the Tri-Cities, where many of our skilled professionals are geographical transplants and the technology-based economic growth we seek often requires highly specific skill sets, effective recruiting is especially critical. But it isn’t just about matching candidates with open positions and signing on the dotted line. In fact, members of the Three Rivers Entrepreneur Network were reminded at a recent presentation that recruiting is very muchmore » about attracting the family unit.« less

  10. The "cradle of glass": incubators for infants in late nineteenth-century France.

    PubMed

    Greene, Gina

    2010-01-01

    This article examines the development of the incubator for premature infants in fin-de-siècle France. During a period of widespread anxiety in France regarding infant mortality and its implications for population growth, physicians in Paris developed and widely promoted the lifesaving technology. This article explores the ways in which the incubator reflected new scientific and symbolic approaches to creating hygienic spaces as well as how it reflected new scientific and symbolic approaches to the traditionally feminine project of infant care. By creating such an isolating and protective milieu around premature infants—an entirely new population of patients—the incubator, I argue, heralded a renegotiation of the boundary between motherhood and medical authority.

  11. Antibunched emission of photon pairs via quantum Zeno blockade.

    PubMed

    Huang, Yu-Ping; Kumar, Prem

    2012-01-20

    We propose a new methodology, namely, the "quantum Zeno blockade," for managing light scattering at a few-photon level in general nonlinear-optical media, such as crystals, fibers, silicon microrings, and atomic vapors. Using this tool, antibunched emission of photon pairs can be achieved, leading to potent quantum-optics applications such as deterministic entanglement generation without the need for heralding. In a practical implementation using an on-chip toroidal microcavity immersed in rubidium vapor, we estimate that high-fidelity entangled photons can be produced on-demand at MHz rates or higher, corresponding to an improvement of ≳10(7) times from the state-of-the-art. © 2012 American Physical Society

  12. Experimental entanglement of 25 individually accessible atomic quantum interfaces

    PubMed Central

    Jiang, Nan; Chang, Wei; Li, Chang; Zhang, Sheng

    2018-01-01

    A quantum interface links the stationary qubits in a quantum memory with flying photonic qubits in optical transmission channels and constitutes a critical element for the future quantum internet. Entanglement of quantum interfaces is an important step for the realization of quantum networks. Through heralded detection of photon interference, we generate multipartite entanglement between 25 (or 9) individually addressable quantum interfaces in a multiplexed atomic quantum memory array and confirm genuine 22-partite (or 9-partite) entanglement. This experimental entanglement of a record-high number of individually addressable quantum interfaces makes an important step toward the realization of quantum networks, long-distance quantum communication, and multipartite quantum information processing. PMID:29725621

  13. Telemedicine diffusion in a developing country: The case of India (March 2004)

    USGS Publications Warehouse

    Pal, A.; Mbarika, V.W.A.; Cobb-Payton, F.; Datta, P.; McCoy, S.

    2005-01-01

    Telemedicine (health-care delivery where physicians examine distant patients using telecommunications technologies) has been heralded as one of several possible solutions to some of the medical dilemmas that face many developing countries. In this study, we examine the current state of telemedicine in a developing country, India. Telemedicine has brought a plethora of benefits to the populace of India, especially those living in rural and remote areas (constituting about 70% of India's population). We discuss three Indian telemedicine implementation cases, consolidate lessons learned from the cases, and culminate with potential researchable critical success factors that account for the growth and modest successes of telemedicine in India. ?? 2005 IEEE.

  14. Tomography and Purification of the Temporal-Mode Structure of Quantum Light

    NASA Astrophysics Data System (ADS)

    Ansari, Vahid; Donohue, John M.; Allgaier, Markus; Sansoni, Linda; Brecht, Benjamin; Roslund, Jonathan; Treps, Nicolas; Harder, Georg; Silberhorn, Christine

    2018-05-01

    High-dimensional quantum information processing promises capabilities beyond the current state of the art, but addressing individual information-carrying modes presents a significant experimental challenge. Here we demonstrate effective high-dimensional operations in the time-frequency domain of nonclassical light. We generate heralded photons with tailored temporal-mode structures through the pulse shaping of a broadband parametric down-conversion pump. We then implement a quantum pulse gate, enabled by dispersion-engineered sum-frequency generation, to project onto programmable temporal modes, reconstructing the quantum state in seven dimensions. We also manipulate the time-frequency structure by selectively removing temporal modes, explicitly demonstrating the effectiveness of engineered nonlinear processes for the mode-selective manipulation of quantum states.

  15. The High Time Resolution Universe

    NASA Astrophysics Data System (ADS)

    Bailes, Matthew; Possenti, Andrea; Johnston, Simon; Kramer, Michael; Burgay, Marta; Bhat, Ramesh; Keith, Michael; Burke-Spolaor, Sarah; van Straten, Willem; Stappers, Benjamin; Bates, Samuel

    2008-04-01

    The Parkes multibeam surveys heralded a new era in pulsar surveys, more than doubling the number of pulsars known. However, at high time resolution, they were severely limited by the analogue backend system, which limited the volume of sky they could effectively survey to just the local 2-3 kpc. Here we propose to use a new digital backend coupled with Australia's most powerful (16 Tflop) supercomputing cluster to conduct three ambitious surveys for millisecond and relativistic pulsars with the Parkes telescope. We hope to discover over 200 new millisecond and relativistic pulsars that will define the recycled pulsar period distribution, supply pulsars for the timing array and aid in our understanding of binary evolution.

  16. Power-efficient production of photon pairs in a tapered chalcogenide microwire

    NASA Astrophysics Data System (ADS)

    Meyer-Scott, Evan; Dot, Audrey; Ahmad, Raja; Li, Lizhu; Rochette, Martin; Jennewein, Thomas

    2015-02-01

    Using tapered fibers of As2Se3 chalcogenide glass, we produce photon pairs at telecommunication wavelengths with low pump powers. We found maximum coincidences-to-accidentals ratios of 2.13 ± 0.07 for degenerate pumping with 3.2 μW average power, and 1.33 ± 0.03 for non-degenerate pumping with 1.0 μW and 1.5 μW average power of the two pumps. Our results show that the ultrahigh nonlinearity in these microwires could allow single-photon pumping to produce photon pairs, enabling the production of large entangled states, heralding of single photons after lossy transmission, and photonic quantum information processing with nonlinear optics.

  17. Color engineering in the age of digital convergence

    NASA Astrophysics Data System (ADS)

    MacDonald, Lindsay W.

    1998-09-01

    Digital color imaging has developed over the past twenty years from specialized scientific applications into the mainstream of computing. In addition to the phenomenal growth of computer processing power and storage capacity, great advances have been made in the capabilities and cost-effectiveness of color imaging peripherals. The majority of imaging applications, including the graphic arts, video and film have made the transition from analogue to digital production methods. Digital convergence of computing, communications and television now heralds new possibilities for multimedia publishing and mobile lifestyles. Color engineering, the application of color science to the design of imaging products, is an emerging discipline that poses exciting challenges to the international color imaging community for training, research and standards.

  18. Neurological soft signs and gray matter changes: a longitudinal analysis in first-episode schizophrenia.

    PubMed

    Kong, Li; Bachmann, Silke; Thomann, Philipp A; Essig, Marco; Schröder, Johannes

    2012-01-01

    Neurological soft signs (NSS) - i.e. discrete deficits of sensory and motor function - are frequently found in schizophrenia and vary with psychopathological symptoms in the course of the disorder. Hence, persistence of NSS herald chronicity in first episode schizophrenia. To investigate the cerebral correlates of persisting NSS over time, 20 patients with first-episode schizophrenia underwent T1 magnetic resonance imaging (MRI) after remission of the acute symptoms and after 1 year of follow-up. NSS were rated on the Heidelberg Scale. Twenty age- and gender-matched control subjects were scanned once. Longitudinal gray matter (GM) changes were measured by using tensor based morphometry (TBM). At follow-up, patients demonstrated significantly decreased NSS scores. For further analysis, the patient sample was dichotomized into patients with decreasing NSS scores and patients with persistently increased scores, respectively. While patients with decreasing NSS exhibited only localized changes within the left frontal lobe, cerebellum, and cingulate gyrus, patients with persistently increased scores showed pronounced GM reductions of the sub-lobar claustrum, cingulate gyrus, cerebellum, frontal lobe, and middle frontal gyrus. Results were confirmed after correction for multiple comparisons. These findings support the hypothesis that persisting NSS refer to progressive cerebral changes in first-episode schizophrenia. Since NSS can be assessed in any clinical environment, this association facilitates the prospect that NSS can help to establish prognosis in first-episode patients with schizophrenia. Copyright © 2011 Elsevier B.V. All rights reserved.

  19. Clinical changes in terminally ill cancer patients and death within 48 h: when should we refer patients to a separate room?

    PubMed

    Hwang, In Cheol; Ahn, Hong Yup; Park, Sang Min; Shim, Jae Yong; Kim, Kyoung Kon

    2013-03-01

    There is scant research concerning the prediction of imminent death, and current studies simply list events "that have already occurred" around 48 h of the death. We sought to determine what events herald the onset of dying process using the length of time from "any change" to death. This is a prospective observational study with chart audit. Inclusion criteria were terminal cancer patients who passed away in a palliative care unit. The analysis was limited to 181 patients who had medical records for their final week. Commonly observed events in the terminally ill were determined and their significant changes were defined beforehand. We selected the statistically significant changes by multiple logistic regression analysis and evaluated their predictive values for "death within 48 h." The median age was 67 years and there were 103 male patients. After adjusting for age, sex, primary cancer site, metastatic site, and cancer treatment, multiple logistic regression analyses for association between the events and "death within 48 h" revealed some significant changes: confused mental state, decreased blood pressure, increased pulse pressure, low oxygen saturation, death rattle, and decreased conscious level. The events that had higher predictability for death within 48 h were decreased blood pressure and low oxygen saturation, and the positive and negative predictive values of their combination were 95.0 and 81.4%, respectively. The most reliable events to predict impending death were decreased blood pressure and low oxygen saturation.

  20. Genomic analysis of adult B-ALL identifies potential markers of shorter survival.

    PubMed

    Patel, Shiven; Mason, Clinton C; Glenn, Martha J; Paxton, Christian N; South, Sara T; Cessna, Melissa H; Asch, Julie; Cobain, Erin F; Bixby, Dale L; Smith, Lauren B; Reshmi, Shalini; Gastier-Foster, Julie M; Schiffman, Joshua D; Miles, Rodney R

    2017-05-01

    B lymphoblastic leukemia (B-ALL) in adults has a higher risk of relapse and lower long-term survival than pediatric B-ALL, but data regarding genetic prognostic biomarkers are much more limited for adult patients. We identified 70 adult B-ALL patients from three institutions and performed genome-wide analysis via single nucleotide polymorphism (SNP) arrays on DNA isolated from their initial diagnostic sample and, when available, relapse bone marrow specimens to identify recurring copy number alterations (CNA). As B-cell developmental genes play a crucial role in this leukemia, we assessed such for recurrent deletions in diagnostic and relapse samples. We confirmed previous findings that the most prevalent deletions of these genes occur in CDKN2A, IKZF1, and PAX5, with several others at lower frequencies. Of the 16 samples having paired diagnostic and relapse samples, 5 showed new deletions in these recurrent B-cell related genes and 8 showed abolishment. Deletion of EBF1 heralded a significant negative prognostic impact on relapse free survival in univariate and multivariate analyses. The combination of both a CDKN2A/B deletion and an IKZF1 alteration (26% of cases) also showed a trend toward predicting worse overall survival compared to having only one or neither of these deletions. These findings add to the understanding of genomic influences on this comparably understudied disease cohort that upon further validation may help identify patients who would benefit from upfront treatment intensification. Copyright © 2017 Elsevier Ltd. All rights reserved.

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