Sample records for variable length records

  1. Artificial neural network predictions of lengths of stay on a post-coronary care unit.

    PubMed

    Mobley, B A; Leasure, R; Davidson, L

    1995-01-01

    To create and validate a model that predicts length of hospital unit stay. Ex post facto. Seventy-four independent admission variables in 15 general categories were utilized to predict possible stays of 1 to 20 days. Laboratory. Records of patients discharged from a post-coronary care unit in early 1993. An artificial neural network was trained on 629 records and tested on an additional 127 records of patients. The absolute disparity between the actual lengths of stays in the test records and the predictions of the network averaged 1.4 days per record, and the actual length of stay was predicted within 1 day 72% of the time. The artificial neural network demonstrated the capacity to utilize common patient admission characteristics to predict lengths of stay. This technology shows promise in aiding timely initiation of treatment and effective resource planning and cost control.

  2. A comparison of extreme rainfall characteristics in the Brazilian Amazon derived from two gridded data sets and a national rain gauge network

    NASA Astrophysics Data System (ADS)

    Clarke, Robin T.; Bulhoes Mendes, Carlos Andre; Costa Buarque, Diogo

    2010-07-01

    Two issues of particular importance for the Amazon watershed are: whether annual maxima obtained from reanalysis and raingauge records agree well enough for the former to be useful in extending records of the latter; and whether reported trends in Amazon annual rainfall are reflected in the behavior of annual extremes in precipitation estimated from reanalyses and raingauge records. To explore these issues, three sets of daily precipitation data (1979-2001) from the Brazilian Amazon were analyzed (NCEP/NCAR and ERA-40 reanalyses, and records from the raingauge network of the Brazilian water resources agency - ANA), using the following variables: (1) mean annual maximum precipitation totals, accumulated over one, two, three and five days; (2) linear trends in these variables; (3) mean length of longest within-year "dry" spell; (4) linear trends in these variables. Comparisons between variables obtained from all three data sources showed that reanalyses underestimated time-trends and mean annual maximum precipitation (over durations of one to five days), and the correlations between reanalysis and spatially-interpolated raingauge estimates were small for these two variables. Both reanalyses over-estimated mean lengths of dry period relative to the mean length recorded by the raingauge network. Correlations between the trends calculated from all three data sources were small. Time-trends averaged over the reanalysis grid-squares, and spatially-interpolated time trends from raingauge data, were all clustered around zero. In conclusion, although the NCEP/NCAR and ERA-40 gridded data-sets may be valuable for studies of inter-annual variability in precipitation totals, they were found to be inappropriate for analysis of precipitation extremes.

  3. Applications of the generalized information processing system (GIPSY)

    USGS Publications Warehouse

    Moody, D.W.; Kays, Olaf

    1972-01-01

    The Generalized Information Processing System (GIPSY) stores and retrieves variable-field, variable-length records consisting of numeric data, textual data, or codes. A particularly noteworthy feature of GIPSY is its ability to search records for words, word stems, prefixes, and suffixes as well as for numeric values. Moreover, retrieved records may be printed on pre-defined formats or formatted as fixed-field, fixed-length records for direct input to other-programs, which facilitates the exchange of data with other systems. At present there are some 22 applications of GIPSY falling in the general areas of bibliography, natural resources information, and management science, This report presents a description of each application including a sample input form, dictionary, and a typical formatted record. It is hoped that these examples will stimulate others to experiment with innovative uses of computer technology.

  4. Predicting length of stay from an electronic patient record system: a primary total knee replacement example.

    PubMed

    Carter, Evelene M; Potts, Henry W W

    2014-04-04

    To investigate whether factors can be identified that significantly affect hospital length of stay from those available in an electronic patient record system, using primary total knee replacements as an example. To investigate whether a model can be produced to predict the length of stay based on these factors to help resource planning and patient expectations on their length of stay. Data were extracted from the electronic patient record system for discharges from primary total knee operations from January 2007 to December 2011 (n=2,130) at one UK hospital and analysed for their effect on length of stay using Mann-Whitney and Kruskal-Wallis tests for discrete data and Spearman's correlation coefficient for continuous data. Models for predicting length of stay for primary total knee replacements were tested using the Poisson regression and the negative binomial modelling techniques. Factors found to have a significant effect on length of stay were age, gender, consultant, discharge destination, deprivation and ethnicity. Applying a negative binomial model to these variables was successful. The model predicted the length of stay of those patients who stayed 4-6 days (~50% of admissions) with 75% accuracy within 2 days (model data). Overall, the model predicted the total days stayed over 5 years to be only 88 days more than actual, a 6.9% uplift (test data). Valuable information can be found about length of stay from the analysis of variables easily extracted from an electronic patient record system. Models can be successfully created to help improve resource planning and from which a simple decision support system can be produced to help patient expectation on their length of stay.

  5. The effect of word length and other sublexical, lexical, and semantic variables on developmental reading deficits.

    PubMed

    De Luca, Maria; Barca, Laura; Burani, Cristina; Zoccolotti, Pierluigi

    2008-12-01

    To examine the effect of word length and several sublexical, and lexico-semantic variables on the reading of Italian children with a developmental reading deficit. Previous studies indicated the role of word length in transparent orthographies. However, several factors that may interact with word length were not controlled for. Seventeen impaired and 34 skilled sixth-grade readers were presented words of different lengths, matched for initial phoneme, bigram frequency, word frequency, age of acquisition, and imageability. Participants were asked to read aloud, as quickly and as accurately as possible. Reaction times at the onset of pronunciation and mispronunciations were recorded. Impaired readers' reaction times indicated a marked effect of word length; in skilled readers, there was no length effect for short words but, rather, a monotonic increase from 6-letter words on. Regression analyses confirmed the role of word length and indicated the influence of word frequency (similar in impaired and skilled readers). No other variables predicted reading latencies. Word length differentially influenced word recognition in impaired versus skilled readers, irrespective of the action of (potentially interfering) sublexical, lexical, and semantic variables. It is proposed that the locus of the length effect is at a perceptual level of analysis. The independent influence of word frequency on the reading performance of both groups of participants indicates the sparing of lexical activation in impaired readers.

  6. Parameter and prediction uncertainty in an optimized terrestrial carbon cycle model: Effects of constraining variables and data record length

    NASA Astrophysics Data System (ADS)

    Ricciuto, Daniel M.; King, Anthony W.; Dragoni, D.; Post, Wilfred M.

    2011-03-01

    Many parameters in terrestrial biogeochemical models are inherently uncertain, leading to uncertainty in predictions of key carbon cycle variables. At observation sites, this uncertainty can be quantified by applying model-data fusion techniques to estimate model parameters using eddy covariance observations and associated biometric data sets as constraints. Uncertainty is reduced as data records become longer and different types of observations are added. We estimate parametric and associated predictive uncertainty at the Morgan Monroe State Forest in Indiana, USA. Parameters in the Local Terrestrial Ecosystem Carbon (LoTEC) are estimated using both synthetic and actual constraints. These model parameters and uncertainties are then used to make predictions of carbon flux for up to 20 years. We find a strong dependence of both parametric and prediction uncertainty on the length of the data record used in the model-data fusion. In this model framework, this dependence is strongly reduced as the data record length increases beyond 5 years. If synthetic initial biomass pool constraints with realistic uncertainties are included in the model-data fusion, prediction uncertainty is reduced by more than 25% when constraining flux records are less than 3 years. If synthetic annual aboveground woody biomass increment constraints are also included, uncertainty is similarly reduced by an additional 25%. When actual observed eddy covariance data are used as constraints, there is still a strong dependence of parameter and prediction uncertainty on data record length, but the results are harder to interpret because of the inability of LoTEC to reproduce observed interannual variations and the confounding effects of model structural error.

  7. Re-description of Echiniscus cavagnaroi Schuster & Grigarick, 1966 (Tardigrada: Heterotardigrada: Echiniscoidea: Echiniscidae) from type material, with new records from Hawaii and Bermuda.

    PubMed

    Meyer, Harry A

    2016-06-13

    The description of Echiniscus cavagnaroi Schuster & Grigarick, 1966 (Tardigrada: Heterotardigrada: Echiniscoidea: Echiniscidae) is emended with new morphometric measurements of the holotype and eleven paratypes. The length of Cirrus A in the holotype (25.2 μm) was only half the 50 μm reported in the original description. Moreover, the largest values for Cirrus A length and Cirrus A to body length ratio for any specimen (40.6 μm, 21%) were also lower than in the original description. Variation in the presence or absence of spines was considerably greater than originally described. Spines C, Dd and E were not present on all specimens (C present in 67%, Dd in 67%, E in 50%). The length of spines Dd and E, when present, varied greatly among specimens. The geographical range of E. cavagnaroi is expanded by new records from the Hawaiian Islands and Bermuda. The species has been reported from southern China; however, the published description of these specimens differs markedly from type specimens in several respects. The presence of E. cavagnaroi sensu stricto in China needs to be confirmed. The high variability in presence or absence and length of spines in Echiniscus cavagnaroi underscores the importance of assessing variability in these characteristics when identifying unknown specimens or describing new species in the genus. This requires using as many specimens as possible and fully reporting variability.

  8. Spacesuit Glove-Induced Hand Trauma and Analysis of Potentially Related Risk Variables

    NASA Technical Reports Server (NTRS)

    Charvat, Chacqueline M.; Norcross, Jason; Reid, Christopher R.; McFarland, Shane M.

    2015-01-01

    Injuries to the hands are common among astronauts who train for extravehicular activity (EVA). When the gloves are pressurized, they restrict movement and create pressure points during tasks, sometimes resulting in pain, muscle fatigue, abrasions, and occasionally more severe injuries such as onycholysis. Glove injuries, both anecdotal and recorded, have been reported during EVA training and flight persistently through NASA's history regardless of mission or glove model. Theories as to causation such as glove-hand fit are common but often lacking in supporting evidence. Previous statistical analysis has evaluated onycholysis in the context of crew anthropometry only. The purpose of this study was to analyze all injuries (as documented in the medical records) and available risk factor variables with the goal to determine engineering and operational controls that may reduce hand injuries due to the EVA glove in the future. A literature review and data mining study were conducted between 2012 and 2014. This study included 179 US NASA crew who trained or completed an EVA between 1981 and 2010 (crossing both Shuttle and ISS eras) and wore either the 4000 Series or Phase VI glove during Extravehicular Mobility Unit (EMU) spacesuit EVA training and flight. All injuries recorded in medical records were analyzed in their association to candidate risk factor variables. Those risk factor variables included demographic characteristics, hand anthropometry, glove fit characteristics, and training/EVA characteristics. Utilizing literature, medical records and anecdotal causation comments recorded in crewmember injury data, investigators were able to identify several risk factors associated with increased risk of glove related injuries. Prime among them were smaller hand anthropometry, duration of individual suited exposures, and improper glove-hand fit as calculated by the difference in the anthropometry middle finger length compared to the baseline EVA glove middle finger length.

  9. Spacesuit Glove-Induced Hand Trauma and Analysis of Potentially Related Risk Variables

    NASA Technical Reports Server (NTRS)

    McFarland, Shane M.; Reid, Christopher R.; Norcross, Jason; Charvat, Jacqueline M.

    2015-01-01

    Injuries to the hands are common among astronauts who train for extravehicular activity (EVA). When the gloves are pressurized, they restrict movement and create pressure points during tasks, sometimes resulting in pain, muscle fatigue, abrasions, and occasionally more severe injuries such as onycholysis. Glove injuries, both anecdotal and recorded, have been reported during EVA training and flight persistently through NASA's history regardless of mission or glove model. Theories as to causation such as glove-hand fit are common but often lacking in supporting evidence. Previous statistical analysis has evaluated onycholysis in the context of crew anthropometry only (Opperman et al 2010). The purpose of this study was to analyze all injuries (as documented in the medical records) and available risk factor variables with the goal to determine engineering and operational controls that may reduce hand injuries due to the EVA glove in the future. A literature review and data mining study were conducted between 2012 and 2014. This study included 179 US NASA crew who trained or completed an EVA between 1981 and 2010 (crossing both Shuttle and ISS eras) and wore either the 4000 Series or Phase VI glove during Extravehicular Mobility Unit (EMU) spacesuit EVA training and flight. All injuries recorded in medical records were analyzed in their association to candidate risk factor variables. Those risk factor variables included demographic characteristics, hand anthropometry, glove fit characteristics, and training/EVA characteristics. Utilizing literature, medical records and anecdotal causation comments recorded in crewmember injury data, investigators were able to identify several risk factors associated with increased risk of glove related injuries. Prime among them were smaller hand anthropometry, duration of individual suited exposures, and improper glove-hand fit as calculated by the difference in the anthropometry middle finger length compared to the baseline EVA glove middle finger length.

  10. Reconstructed streamflow for Citarum River, Java, Indonesia: linkages to tropical climate dynamics

    NASA Astrophysics Data System (ADS)

    D'Arrigo, Rosanne; Abram, Nerilie; Ummenhofer, Caroline; Palmer, Jonathan; Mudelsee, Manfred

    2011-02-01

    The Citarum river basin of western Java, Indonesia, which supplies water to 10 million residents in Jakarta, has become increasingly vulnerable to anthropogenic change. Citarum's streamflow record, only ~45 years in length (1963-present), is too short for understanding the full range of hydrometeorological variability in this important region. Here we present a tree-ring based reconstruction of September-November Citarum streamflow (AD 1759-2006), one of the first such records available for monsoon Asia. Close coupling is observed between decreased tree growth and low streamflow levels, which in turn are associated with drought caused by ENSO warm events in the tropical Pacific and Indian Ocean positive dipole-type variability. Over the full length of record, reconstructed variance was at its weakest during the interval from ~1905-1960, overlapping with a period of unusually-low variability (1920-1960) in the ENSO-Indian Ocean dipole systems. In subsequent decades, increased variance in both the streamflow anomalies and a coral-based SST reconstruction of the Indian Ocean Dipole Mode signal the potential for intensified drought activity and related consequences for water supply and crop productivity in western Java, where much of the country's rice is grown.

  11. Data reduction for cough studies using distribution of audio frequency content

    PubMed Central

    2012-01-01

    Background Recent studies suggest that objectively quantifying coughing in audio recordings offers a novel means to understand coughing and assess treatments. Currently, manual cough counting is the most accurate method for quantifying coughing. However, the demand of manually counting cough records is substantial, demonstrating a need to reduce record lengths prior to counting whilst preserving the coughs within them. This study tested the performance of an algorithm developed for this purpose. Methods 20 subjects were recruited (5 healthy smokers and non-smokers, 5 chronic cough, 5 chronic obstructive pulmonary disease and 5 asthma), fitted with an ambulatory recording system and recorded for 24 hours. The recordings produced were divided into 15 min segments and counted. Periods of inactive audio in each segment were removed using the median frequency and power of the audio signal and the resulting files re-counted. Results The median resultant segment length was 13.9 s (IQR 56.4 s) and median 24 hr recording length 62.4 min (IQR 100.4). A median of 0.0 coughs/h (IQR 0.0-0.2) were erroneously removed and the variability in the resultant cough counts was comparable to that between manual cough counts. The largest error was seen in asthmatic patients, but still only 1.0% coughs/h were missed. Conclusions These data show that a system which measures signal activity using the median audio frequency can substantially reduce record lengths without significantly compromising the coughs contained within them. PMID:23231789

  12. Principal component analysis of biometric traits to reveal body confirmation in local hill cattle of Himalayan state of Himachal Pradesh, India.

    PubMed

    Verma, Deepak; Sankhyan, Varun; Katoch, Sanjeet; Thakur, Yash Pal

    2015-12-01

    In the present study, biometric traits (body length [BL], heart girth [HG], paunch girth (PG), forelimb length (FLL), hind limb length (HLL), face length, forehead width, forehead length, height at hump, hump length (HL), hook to hook distance, pin to pin distance, tail length (TL), TL up to switch, horn length, horn circumference, and ear length were studied in 218 adult hill cattle of Himachal Pradesh for phenotypic characterization. Morphological and biometrical observations were recorded on 218 hill cattle randomly selected from different districts within the breeding tract. Multivariate statistics and principal component analysis are used to account for the maximum portion of variation present in the original set of variables with a minimum number of composite variables through Statistical software, SAS 9.2. Five components were extracted which accounted for 65.9% of variance. The first component explained general body confirmation and explained 34.7% variation. It was represented by significant loading for BL, HG, PG, FLL, and HLL. Communality estimate ranged from 0.41 (HL) to 0.88 (TL). Second, third, fourth, and fifth component had a high loading for tail characteristics, horn characteristics, facial biometrics, and rear body, respectively. The result of component analysis of biometric traits suggested that indigenous hill cattle of Himachal Pradesh are small and compact size cattle with a medium hump, horizontally placed short ears, and a long tail. The study also revealed that factors extracted from the present investigation could be used in breeding programs with sufficient reduction in the number of biometric traits to be recorded to explain the body confirmation.

  13. Landsat Surface Reflectance Climate Data Records

    USGS Publications Warehouse

    ,

    2014-01-01

    Landsat Surface Reflectance Climate Data Records (CDRs) are high level Landsat data products that support land surface change studies. Climate Data Records, as defined by the National Research Council, are a time series of measurements with sufficient length, consistency, and continuity to identify climate variability and change. The U.S. Geological Survey (USGS) is using the valuable 40-year Landsat archive to create CDRs that can be used to document changes to Earth’s terrestrial environment.

  14. Evidence of multidecadal climate variability and the Atlantic Multidecadal Oscillation from a Gulf of Mexico sea-surface temperature-proxy record

    USGS Publications Warehouse

    Poore, R.Z.; DeLong, K.L.; Richey, J.N.; Quinn, T.M.

    2009-01-01

    A comparison of a Mg/Ca-based sea-surface temperature (SST)-anomaly record from the northern Gulf of Mexico, a calculated index of variability in observed North Atlantic SST known as the Atlantic Multidecadal Oscillation (AMO), and a tree-ring reconstruction of the AMO contain similar patterns of variation over the last 110 years. Thus, the multidecadal variability observed in the instrumental record is present in the tree-ring and Mg/Ca proxy data. Frequency analysis of the Gulf of Mexico SST record and the tree-ring AMO reconstruction from 1550 to 1990 found similar multidecadal-scale periodicities (???30-60 years). This multidecadal periodicity is about half the observed (60-80 years) variability identified in the AMO for the 20th century. The historical records of hurricane landfalls reveal increased landfalls in the Gulf Coast region during time intervals when the AMO index is positive (warmer SST), and decreased landfalls when the AMO index is negative (cooler SST). Thus, we conclude that alternating intervals of high and low hurricane landfall occurrences may continue on multidecadal timescales along the northern Gulf Coast. However, given the short length of the instrumental record, the actual frequency and stability of the AMO are uncertain, and additional AMO proxy records are needed to establish the character of multidecadal-scale SST variability in the North Atlantic. ?? 2009 US Government.

  15. Analysis of threats to research validity introduced by audio recording clinic visits: Selection bias, Hawthorne effect, both, or neither?

    PubMed Central

    Henry, Stephen G.; Jerant, Anthony; Iosif, Ana-Maria; Feldman, Mitchell D.; Cipri, Camille; Kravitz, Richard L.

    2015-01-01

    Objective To identify factors associated with participant consent to record visits; to estimate effects of recording on patient-clinician interactions Methods Secondary analysis of data from a randomized trial studying communication about depression; participants were asked for optional consent to audio record study visits. Multiple logistic regression was used to model likelihood of patient and clinician consent. Multivariable regression and propensity score analyses were used to estimate effects of audio recording on 6 dependent variables: discussion of depressive symptoms, preventive health, and depression diagnosis; depression treatment recommendations; visit length; visit difficulty. Results Of 867 visits involving 135 primary care clinicians, 39% were recorded. For clinicians, only working in academic settings (P=0.003) and having worked longer at their current practice (P=0.02) were associated with increased likelihood of consent. For patients, white race (P=0.002) and diabetes (P=0.03) were associated with increased likelihood of consent. Neither multivariable regression nor propensity score analyses revealed any significant effects of recording on the variables examined. Conclusion Few clinician or patient characteristics were significantly associated with consent. Audio recording had no significant effect on any dependent variables. Practice Implications Benefits of recording clinic visits likely outweigh the risks of bias in this setting. PMID:25837372

  16. Hunting of roe deer and wild boar in Germany: Is non-lead ammunition suitable for hunting?

    PubMed

    Martin, Annett; Gremse, Carl; Selhorst, Thomas; Bandick, Niels; Müller-Graf, Christine; Greiner, Matthias; Lahrssen-Wiederholt, Monika

    2017-01-01

    Non-lead hunting ammunition is an alternative to bullets that contain lead. The use of lead ammunition can result in severe contamination of game meat, thus posing a health risk to consumers. With any kind of ammunition for hunting, the terminal effectiveness of bullets is an animal welfare issue. Doubts about the effectiveness of non-lead bullets for a humane kill of game animals in hunting have been discussed. The length of the escape distance after the shot has been used previously as an indicator for bullet performance. The object of this study was to determine how the bullet material (lead or non-lead) influences the observed escape distances. 1,234 records of the shooting of roe deer (Capreolus capreolus) and 825 records of the shooting of wild boar (Sus scrofa) were evaluated. As the bullet material cannot be regarded as the sole cause of variability of escape distances, interactions of other potential influencing variables like shot placement, shooting distance, were analyzed using conditional regression trees and two-part hurdle models. The length of the escape distance is not influenced by the use of lead or non-lead ammunition with either roe deer or wild boar. With roe deer, the length of the escape distance is influenced significantly by the shot placement and the type of hunting. Increasing shooting distances increased the length of the escape distance. With wild boar, shot placement and the age of the animals were found to be a significant influencing factor on the length of the escape distance. The length of the escape distance can be used as an indicator for adequate bullet effectiveness for humane killings of game animals in hunting.Non-lead bullets already exist which have an equally reliable killing effect as lead bullets.

  17. The Association between Health Information Technology Adoption and Family Physicians' Practice Patterns in Canada: Evidence from 2007 and 2010 National Physician Surveys

    PubMed Central

    Sarma, Sisira; Hajizadeh, Mohammad; Thind, Amardeep; Chan, Rick

    2013-01-01

    Objective: To describe the association between health information technology (HIT) adoption and family physicians' patient visit length in Canada after controlling for physician and practice characteristics. Method: HIT adoption is defined in terms of four types of HIT usage: no HIT use (NO), basic HIT use without electronic medical record system (HIT), basic HIT use with electronic medical record (EMR) and advanced HIT use (EMR + HIT). The outcome variable is the average time spent on a patient visit (visit length). The data for this study came from the 2007 and 2010 National Physician Surveys. A log-linear model was used to analyze our visit length outcome. Results: The average time worked per week was found to be in the neighbourhood of 36 hours in both 2007 and 2010, but users of EMR and EMR + HIT were undertaking fewer patient visits per week relative to NO users. Multivariable analysis showed that EMR and EMR + HIT were associated with longer average time spent per patient visit by about 7.7% (p<0.05) and 6.7% (p<0.01), respectively, compared to NO users in 2007. In 2010, EMR was not statistically significant and EMR + HIT was associated with a 4% (p<0.1) increased visit length. A variety of practice-related variables such as the mode of remuneration, work setting and interprofessional practice influenced visit length in the expected direction. Conclusion: Use of HIT is found to be associated with fewer patient visits and longer visit length among family physicians in Canada relative to NO users, but this association weakened in the multivariable analysis of 2010. PMID:23968677

  18. Exploring the relationship between stride, stature and hand size for forensic assessment.

    PubMed

    Guest, Richard; Miguel-Hurtado, Oscar; Stevenage, Sarah; Black, Sue

    2017-11-01

    Forensic evidence often relies on a combination of accurately recorded measurements, estimated measurements from landmark data such as a subject's stature given a known measurement within an image, and inferred data. In this study a novel dataset is used to explore linkages between hand measurements, stature, leg length and stride. These three measurements replicate the type of evidence found in surveillance videos with stride being extracted from an automated gait analysis system. Through correlations and regression modelling, it is possible to generate accurate predictions of stature from hand size, leg length and stride length (and vice versa), and to predict leg and stride length from hand size with, or without, stature as an intermediary variable. The study also shows improved accuracy when a subject's sex is known a-priori. Our method and models indicate the possibility of calculating or checking relationships between a suspect's physical measurements, particularly when only one component is captured as an accurately recorded measurement. Copyright © 2017 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  19. The Harvard Automated Processing Pipeline for Electroencephalography (HAPPE): Standardized Processing Software for Developmental and High-Artifact Data.

    PubMed

    Gabard-Durnam, Laurel J; Mendez Leal, Adriana S; Wilkinson, Carol L; Levin, April R

    2018-01-01

    Electroenchephalography (EEG) recordings collected with developmental populations present particular challenges from a data processing perspective. These EEGs have a high degree of artifact contamination and often short recording lengths. As both sample sizes and EEG channel densities increase, traditional processing approaches like manual data rejection are becoming unsustainable. Moreover, such subjective approaches preclude standardized metrics of data quality, despite the heightened importance of such measures for EEGs with high rates of initial artifact contamination. There is presently a paucity of automated resources for processing these EEG data and no consistent reporting of data quality measures. To address these challenges, we propose the Harvard Automated Processing Pipeline for EEG (HAPPE) as a standardized, automated pipeline compatible with EEG recordings of variable lengths and artifact contamination levels, including high-artifact and short EEG recordings from young children or those with neurodevelopmental disorders. HAPPE processes event-related and resting-state EEG data from raw files through a series of filtering, artifact rejection, and re-referencing steps to processed EEG suitable for time-frequency-domain analyses. HAPPE also includes a post-processing report of data quality metrics to facilitate the evaluation and reporting of data quality in a standardized manner. Here, we describe each processing step in HAPPE, perform an example analysis with EEG files we have made freely available, and show that HAPPE outperforms seven alternative, widely-used processing approaches. HAPPE removes more artifact than all alternative approaches while simultaneously preserving greater or equivalent amounts of EEG signal in almost all instances. We also provide distributions of HAPPE's data quality metrics in an 867 file dataset as a reference distribution and in support of HAPPE's performance across EEG data with variable artifact contamination and recording lengths. HAPPE software is freely available under the terms of the GNU General Public License at https://github.com/lcnhappe/happe.

  20. The Harvard Automated Processing Pipeline for Electroencephalography (HAPPE): Standardized Processing Software for Developmental and High-Artifact Data

    PubMed Central

    Gabard-Durnam, Laurel J.; Mendez Leal, Adriana S.; Wilkinson, Carol L.; Levin, April R.

    2018-01-01

    Electroenchephalography (EEG) recordings collected with developmental populations present particular challenges from a data processing perspective. These EEGs have a high degree of artifact contamination and often short recording lengths. As both sample sizes and EEG channel densities increase, traditional processing approaches like manual data rejection are becoming unsustainable. Moreover, such subjective approaches preclude standardized metrics of data quality, despite the heightened importance of such measures for EEGs with high rates of initial artifact contamination. There is presently a paucity of automated resources for processing these EEG data and no consistent reporting of data quality measures. To address these challenges, we propose the Harvard Automated Processing Pipeline for EEG (HAPPE) as a standardized, automated pipeline compatible with EEG recordings of variable lengths and artifact contamination levels, including high-artifact and short EEG recordings from young children or those with neurodevelopmental disorders. HAPPE processes event-related and resting-state EEG data from raw files through a series of filtering, artifact rejection, and re-referencing steps to processed EEG suitable for time-frequency-domain analyses. HAPPE also includes a post-processing report of data quality metrics to facilitate the evaluation and reporting of data quality in a standardized manner. Here, we describe each processing step in HAPPE, perform an example analysis with EEG files we have made freely available, and show that HAPPE outperforms seven alternative, widely-used processing approaches. HAPPE removes more artifact than all alternative approaches while simultaneously preserving greater or equivalent amounts of EEG signal in almost all instances. We also provide distributions of HAPPE's data quality metrics in an 867 file dataset as a reference distribution and in support of HAPPE's performance across EEG data with variable artifact contamination and recording lengths. HAPPE software is freely available under the terms of the GNU General Public License at https://github.com/lcnhappe/happe. PMID:29535597

  1. Survey of Postharvest Quality Characteristics During Long-Term Farmers Stock Storage

    USDA-ARS?s Scientific Manuscript database

    The length of time that peanuts remain in farmers stock storage is variable. With the record harvest of the 2012 peanut crop, some peanuts remained in farmers stock storage for up to 12 months before being shelled and placed in cold storage or shipped to the manufacturer. To investigate potential ...

  2. An Eight-Century High-Resolution Paleoclimate Record From the Cariaco Basin: Baseline Variability and the 20th Century

    NASA Astrophysics Data System (ADS)

    Black, D. E.; Thunell, R. C.; Kaplan, A.; Tappa, E. J.; Peterson, L. C.

    2007-12-01

    The Cariaco Basin, Venezuela is well-positioned to record a detailed history of surface ocean changes along the southern margin of the Caribbean and the tropical Atlantic. Varved, high deposition rate sediments deposited under anoxic conditions and an abundance of well-preserved microfossils result in one of the few marine records capable of preserving evidence of interannual- to decadal-scale climate variability in the tropical Atlantic. Here we present Mg/Ca and stable oxygen isotope data with sub-decadal resolution derived from sediments deposited over the last 800 years. Mg/Ca measured on the planktic foraminifer Globigerina bulloides from a Cariaco Basin sediment core strongly correlates with spring (March-May) instrumental SSTs between AD 1870 and 1990. The long-term record displays a surprising amount of variability for a tropical location. The temperature swings are not necessarily related to local upwelling variability, but instead represent wider conditions in the Caribbean and western tropical Atlantic. The Mg/Ca-SST record also captures the decadal and multidecadal variability observed in global land and sea surface temperature anomalies, and correlates with Atlantic tropical storm and hurricane frequency over the late-19th and 20th centuries. On average, 20th century temperatures are not the warmest in the entire record, but they do show the largest increase in magnitude and fastest rate of SST change over the last eight hundred years. Stable oxygen isotope data also correlate well with instrumental SSTs, but not over the full instrumental record. Poor correlations with early instrumental SST data suggest a salinity overprint. However, reconstructing δ- water variability using combined Mg/Ca and δ18O data is not straightforward as the δ- water/salinity relationship varies seasonally in the Cariaco Basin. Comparisons with percent titanium data suggest intervals of both local and regional surface salinity changes over the length of the record.

  3. Measuring a diffusion coefficient by single-particle tracking: statistical analysis of experimental mean squared displacement curves.

    PubMed

    Ernst, Dominique; Köhler, Jürgen

    2013-01-21

    We provide experimental results on the accuracy of diffusion coefficients obtained by a mean squared displacement (MSD) analysis of single-particle trajectories. We have recorded very long trajectories comprising more than 1.5 × 10(5) data points and decomposed these long trajectories into shorter segments providing us with ensembles of trajectories of variable lengths. This enabled a statistical analysis of the resulting MSD curves as a function of the lengths of the segments. We find that the relative error of the diffusion coefficient can be minimized by taking an optimum number of points into account for fitting the MSD curves, and that this optimum does not depend on the segment length. Yet, the magnitude of the relative error for the diffusion coefficient does, and achieving an accuracy in the order of 10% requires the recording of trajectories with about 1000 data points. Finally, we compare our results with theoretical predictions and find very good qualitative and quantitative agreement between experiment and theory.

  4. Entropy-based complexity of the cardiovascular control in Parkinson disease: comparison between binning and k-nearest-neighbor approaches.

    PubMed

    Porta, Alberto; Bari, Vlasta; Bassani, Tito; Marchi, Andrea; Tassin, Stefano; Canesi, Margherita; Barbic, Franca; Furlan, Raffaello

    2013-01-01

    Entropy-based approaches are frequently used to quantify complexity of short-term cardiovascular control from spontaneous beat-to-beat variability of heart period (HP) and systolic arterial pressure (SAP). Among these tools the ones optimizing a critical parameter such as the pattern length are receiving more and more attention. This study compares two entropy-based techniques for the quantification of complexity making use of completely different strategies to optimize the pattern length. Comparison was carried out over HP and SAP variability series recorded from 12 Parkinson's disease (PD) patients without orthostatic hypotension or symptoms of orthostatic intolerance and 12 age-matched healthy control (HC) subjects. Regardless of the method, complexity of cardiovascular control increased in PD group, thus suggesting the early impairment of cardiovascular function.

  5. Kinematic Variables Evolution During a 200-m Maximum Test in Young Paddlers

    PubMed Central

    Vaquero-Cristóbal, Raquel; Alacid, Fernando; López-Plaza, Daniel; Muyor, José María; López-Miñarro, Pedro A.

    2013-01-01

    The objective of this research was to determine the kinematic variables evolution in a sprint canoeing maximal test over 200 m, comparing women and men kayak paddlers and men canoeists. Speed evolution, cycle frequency, cycle length and cycle index were analysed each 50 m section in fifty-two young paddlers (20 male kayakers, 17 female kayakers and 15 male canoeists; 13–14 years-old). Recordings were taken from a boat which followed each paddler trial in order to measure the variables cited above. Kinematic evolution was similar in the three categories, the speed and cycle index decreased through the test after the first 50 m. Significant differences were observed among most of the sections in speed and the cycle index (p<0.05 and <0.01, respectively). Cycle length remained stable showing the lowest values in the first section when compared with the others (p<0.01). Cycle frequency progressively decreased along the distance. Significant differences were identified in the majority of the sections (p<0.01). Men kayakers attained higher values in all the variables than women kayakers and men canoeists, but only such variables as speed, cycle length and cycle index were observed to be significantly higher (p<0.01). Moreover, lower kinematic values were obtained from men canoeists. The study of the evolution of kinematic variables can provide valuable information for athletes and coaches while planning training sessions and competitions. PMID:24235980

  6. Linear variability of gait according to socioeconomic status in elderly

    PubMed Central

    2016-01-01

    Aim: To evaluate the linear variability of comfortable gait according to socioeconomic status in community-dwelling elderly. Method: For this cross-sectional observational study 63 self- functioning elderly were categorized according to the socioeconomic level on medium-low (n= 33, age 69.0 ± 5.0 years) and medium-high (n= 30, age 71.0 ± 6.0 years). Each participant was asked to perform comfortable gait speed for 3 min on an 40 meters elliptical circuit, recording in video five strides which were transformed into frames, determining the minimum foot clearance, maximum foot clearance and stride length. The intra-group linear variability was calculated by the coefficient of variation in percent. Results: The trajectory parameters variability is not different according to socioeconomic status with a 30% (range= 15-55%) for the minimum foot clearance and 6% (range= 3-8%) in maximum foot clearance. Meanwhile, the stride length consistently was more variable in the medium-low socioeconomic status for the overall sample (p= 0.004), female (p= 0.041) and male gender (p= 0.007), with values near 4% ​​(range = 2.5-5.0%) in the medium-low and 2% (range = 1.5-3.5%) in the medium-high. Conclusions: The intra-group linear variability is consistently higher and within reference parameters for stride length during comfortable gait for elderly belonging to medium-low socioeconomic status. This might be indicative of greater complexity and consequent motor adaptability. PMID:27546931

  7. A scheme for recording a fast process at nanosecond scale by using digital holographic interferometry with continuous wave laser

    NASA Astrophysics Data System (ADS)

    Wang, Jun; Zhao, Jianlin; Di, Jianglei; Jiang, Biqiang

    2015-04-01

    A scheme for recording fast process at nanosecond scale by using digital holographic interferometry with continuous wave (CW) laser is described and demonstrated experimentally, which employs delayed-time fibers and angular multiplexing technique and can realize the variable temporal resolution at nanosecond scale and different measured depths of object field at certain temporal resolution. The actual delay-time is controlled by two delayed-time fibers with different lengths. The object field information in two different states can be simultaneously recorded in a composite hologram. This scheme is also suitable for recording fast process at picosecond scale, by using an electro-optic modulator.

  8. Recurrence Quantification Analysis of Sentence-Level Speech Kinematics.

    PubMed

    Jackson, Eric S; Tiede, Mark; Riley, Michael A; Whalen, D H

    2016-12-01

    Current approaches to assessing sentence-level speech variability rely on measures that quantify variability across utterances and use normalization procedures that alter raw trajectory data. The current work tests the feasibility of a less restrictive nonlinear approach-recurrence quantification analysis (RQA)-via a procedural example and subsequent analysis of kinematic data. To test the feasibility of RQA, lip aperture (i.e., the Euclidean distance between lip-tracking sensors) was recorded for 21 typically developing adult speakers during production of a simple utterance. The utterance was produced in isolation and in carrier structures differing just in length or in length and complexity. Four RQA indices were calculated: percent recurrence (%REC), percent determinism (%DET), stability (MAXLINE), and stationarity (TREND). Percent determinism (%DET) decreased only for the most linguistically complex sentence; MAXLINE decreased as a function of linguistic complexity but increased for the longer-only sentence; TREND decreased as a function of both length and linguistic complexity. This research note demonstrates the feasibility of using RQA as a tool to compare speech variability across speakers and groups. RQA offers promise as a technique to assess effects of potential stressors (e.g., linguistic or cognitive factors) on the speech production system.

  9. Recurrence Quantification Analysis of Sentence-Level Speech Kinematics

    PubMed Central

    Tiede, Mark; Riley, Michael A.; Whalen, D. H.

    2016-01-01

    Purpose Current approaches to assessing sentence-level speech variability rely on measures that quantify variability across utterances and use normalization procedures that alter raw trajectory data. The current work tests the feasibility of a less restrictive nonlinear approach—recurrence quantification analysis (RQA)—via a procedural example and subsequent analysis of kinematic data. Method To test the feasibility of RQA, lip aperture (i.e., the Euclidean distance between lip-tracking sensors) was recorded for 21 typically developing adult speakers during production of a simple utterance. The utterance was produced in isolation and in carrier structures differing just in length or in length and complexity. Four RQA indices were calculated: percent recurrence (%REC), percent determinism (%DET), stability (MAXLINE), and stationarity (TREND). Results Percent determinism (%DET) decreased only for the most linguistically complex sentence; MAXLINE decreased as a function of linguistic complexity but increased for the longer-only sentence; TREND decreased as a function of both length and linguistic complexity. Conclusions This research note demonstrates the feasibility of using RQA as a tool to compare speech variability across speakers and groups. RQA offers promise as a technique to assess effects of potential stressors (e.g., linguistic or cognitive factors) on the speech production system. PMID:27824987

  10. Revisiting speech rate and utterance length manipulations in stuttering speakers.

    PubMed

    Blomgren, Michael; Goberman, Alexander M

    2008-01-01

    The goal of this study was to evaluate stuttering frequency across a multidimensional (2x2) hierarchy of speech performance tasks. Specifically, this study examined the interaction between changes in length of utterance and levels of speech rate stability. Forty-four adult male speakers participated in the study (22 stuttering speakers and 22 non-stuttering speakers). Participants were audio and video recorded while producing a spontaneous speech task and four different experimental speaking tasks. The four experimental speaking tasks involved reading a list of 45 words and a list 45 phrases two times each. One reading of each list involved speaking at a steady habitual rate (habitual rate tasks) and another reading involved producing each list at a variable speaking rate (variable rate tasks). For the variable rate tasks, participants were directed to produce words or phrases at randomly ordered slow, habitual, and fast rates. The stuttering speakers exhibited significantly more stuttering on the variable rate tasks than on the habitual rate tasks. In addition, the stuttering speakers exhibited significantly more stuttering on the first word of the phrase length tasks compared to the single word tasks. Overall, the results indicated that varying levels of both utterance length and temporal complexity function to modulate stuttering frequency in adult stuttering speakers. Discussion focuses on issues of speech performance according to stuttering severity and possible clinical implications. The reader will learn about and be able to: (1) describe the mediating effects of length of utterance and speech rate on the frequency of stuttering in stuttering speakers; (2) understand the rationale behind multidimensional skill performance matrices; and (3) describe possible applications of motor skill performance matrices to stuttering therapy.

  11. Total ozone trend over Cairo

    NASA Technical Reports Server (NTRS)

    Hassan, G. K. Y.

    1994-01-01

    A world wide interest in protecting ozone layer against manmade effects is now increasing. Assessment of the ozone depletion due to these activities depends on how successfully we can separate the natural variabilities from the data. The monthly mean values of total ozone over Cairo (30 05N) for the period 1968-1988, have been analyzed using the power spectral analysis technique. The technique used in this analysis does not depend on a pre-understanding of the natural fluctuations in the ozone data. The method depends on increasing the resolution of the spectral peaks in order to obtain the more accurate sinusoidal fluctuations with wavelength equal to or less than record length. Also it handles the possible sinusoidal fluctuations with wavelength equal to or less than record length. The results show that it is possible to detect some of the well known national fluctuations in the ozone record such as annual, semiannual, quasi-biennial and quasi-quadrennial oscillations. After separating the natural fluctuations from the ozone record, the trend analysis of total ozone over Cairo showed that a decrease of about -1.2% per decade has occurred since 1979.

  12. Coralline algal Barium as indicator for 20th century northwestern North Atlantic surface ocean freshwater variability

    PubMed Central

    Hetzinger, S.; Halfar, J.; Zack, T.; Mecking, J. V.; Kunz, B. E.; Jacob, D. E.; Adey, W. H.

    2013-01-01

    During the past decades climate and freshwater dynamics in the northwestern North Atlantic have undergone major changes. Large-scale freshening episodes, related to polar freshwater pulses, have had a strong influence on ocean variability in this climatically important region. However, little is known about variability before 1950, mainly due to the lack of long-term high-resolution marine proxy archives. Here we present the first multidecadal-length records of annually resolved Ba/Ca variations from Northwest Atlantic coralline algae. We observe positive relationships between algal Ba/Ca ratios from two Newfoundland sites and salinity observations back to 1950. Both records capture episodical multi-year freshening events during the 20th century. Variability in algal Ba/Ca is sensitive to freshwater-induced changes in upper ocean stratification, which affect the transport of cold, Ba-enriched deep waters onto the shelf (highly stratified equals less Ba/Ca). Algal Ba/Ca ratios therefore may serve as a new resource for reconstructing past surface ocean freshwater changes. PMID:23636135

  13. Coralline algal barium as indicator for 20th century northwestern North Atlantic surface ocean freshwater variability.

    PubMed

    Hetzinger, S; Halfar, J; Zack, T; Mecking, J V; Kunz, B E; Jacob, D E; Adey, W H

    2013-01-01

    During the past decades climate and freshwater dynamics in the northwestern North Atlantic have undergone major changes. Large-scale freshening episodes, related to polar freshwater pulses, have had a strong influence on ocean variability in this climatically important region. However, little is known about variability before 1950, mainly due to the lack of long-term high-resolution marine proxy archives. Here we present the first multidecadal-length records of annually resolved Ba/Ca variations from Northwest Atlantic coralline algae. We observe positive relationships between algal Ba/Ca ratios from two Newfoundland sites and salinity observations back to 1950. Both records capture episodical multi-year freshening events during the 20th century. Variability in algal Ba/Ca is sensitive to freshwater-induced changes in upper ocean stratification, which affect the transport of cold, Ba-enriched deep waters onto the shelf (highly stratified equals less Ba/Ca). Algal Ba/Ca ratios therefore may serve as a new resource for reconstructing past surface ocean freshwater changes.

  14. Vocal tract length and formant frequency dispersion correlate with body size in rhesus macaques.

    PubMed

    Fitch, W T

    1997-08-01

    Body weight, length, and vocal tract length were measured for 23 rhesus macaques (Macaca mulatta) of various sizes using radiographs and computer graphic techniques. linear predictive coding analysis of tape-recorded threat vocalizations were used to determine vocal tract resonance frequencies ("formants") for the same animals. A new acoustic variable is proposed, "formant dispersion," which should theoretically depend upon vocal tract length. Formant dispersion is the averaged difference between successive formant frequencies, and was found to be closely tied to both vocal tract length and body size. Despite the common claim that voice fundamental frequency (F0) provides an acoustic indication of body size, repeated investigations have failed to support such a relationship in many vertebrate species including humans. Formant dispersion, unlike voice pitch, is proposed to be a reliable predictor of body size in macaques, and probably many other species.

  15. Hunting of roe deer and wild boar in Germany: Is non-lead ammunition suitable for hunting?

    PubMed Central

    Gremse, Carl; Selhorst, Thomas; Bandick, Niels; Müller-Graf, Christine; Greiner, Matthias; Lahrssen-Wiederholt, Monika

    2017-01-01

    Background Non-lead hunting ammunition is an alternative to bullets that contain lead. The use of lead ammunition can result in severe contamination of game meat, thus posing a health risk to consumers. With any kind of ammunition for hunting, the terminal effectiveness of bullets is an animal welfare issue. Doubts about the effectiveness of non-lead bullets for a humane kill of game animals in hunting have been discussed. The length of the escape distance after the shot has been used previously as an indicator for bullet performance. Objective The object of this study was to determine how the bullet material (lead or non-lead) influences the observed escape distances. Methods 1,234 records of the shooting of roe deer (Capreolus capreolus) and 825 records of the shooting of wild boar (Sus scrofa) were evaluated. As the bullet material cannot be regarded as the sole cause of variability of escape distances, interactions of other potential influencing variables like shot placement, shooting distance, were analyzed using conditional regression trees and two-part hurdle models. Results The length of the escape distance is not influenced by the use of lead or non-lead ammunition with either roe deer or wild boar. With roe deer, the length of the escape distance is influenced significantly by the shot placement and the type of hunting. Increasing shooting distances increased the length of the escape distance. With wild boar, shot placement and the age of the animals were found to be a significant influencing factor on the length of the escape distance. Conclusions The length of the escape distance can be used as an indicator for adequate bullet effectiveness for humane killings of game animals in hunting.Non-lead bullets already exist which have an equally reliable killing effect as lead bullets. PMID:28926620

  16. Estimating trends in the global mean temperature record

    NASA Astrophysics Data System (ADS)

    Poppick, Andrew; Moyer, Elisabeth J.; Stein, Michael L.

    2017-06-01

    Given uncertainties in physical theory and numerical climate simulations, the historical temperature record is often used as a source of empirical information about climate change. Many historical trend analyses appear to de-emphasize physical and statistical assumptions: examples include regression models that treat time rather than radiative forcing as the relevant covariate, and time series methods that account for internal variability in nonparametric rather than parametric ways. However, given a limited data record and the presence of internal variability, estimating radiatively forced temperature trends in the historical record necessarily requires some assumptions. Ostensibly empirical methods can also involve an inherent conflict in assumptions: they require data records that are short enough for naive trend models to be applicable, but long enough for long-timescale internal variability to be accounted for. In the context of global mean temperatures, empirical methods that appear to de-emphasize assumptions can therefore produce misleading inferences, because the trend over the twentieth century is complex and the scale of temporal correlation is long relative to the length of the data record. We illustrate here how a simple but physically motivated trend model can provide better-fitting and more broadly applicable trend estimates and can allow for a wider array of questions to be addressed. In particular, the model allows one to distinguish, within a single statistical framework, between uncertainties in the shorter-term vs. longer-term response to radiative forcing, with implications not only on historical trends but also on uncertainties in future projections. We also investigate the consequence on inferred uncertainties of the choice of a statistical description of internal variability. While nonparametric methods may seem to avoid making explicit assumptions, we demonstrate how even misspecified parametric statistical methods, if attuned to the important characteristics of internal variability, can result in more accurate uncertainty statements about trends.

  17. Gait parameter risk factors for falls under simple and dual task conditions in cognitively impaired older people.

    PubMed

    Taylor, Morag E; Delbaere, Kim; Mikolaizak, A Stefanie; Lord, Stephen R; Close, Jacqueline C T

    2013-01-01

    Impaired gait may contribute to the increased rate of falls in cognitively impaired older people. We investigated whether gait under simple and dual task conditions could predict falls in this group. The study sample consisted of 64 community dwelling older people with mild to moderate cognitive impairment. Participants walked at their preferred speed under three conditions: (a) simple walking, (b) walking while carrying a glass of water and (c) walking while counting backwards from 30. Spatiotemporal gait parameters were measured using the GAITRite(®) mat. Falls were recorded prospectively for 12months with the assistance of carers. Twenty-two (35%) people fell two or more times in the 12month follow-up period. There was a significant main effect of gait condition and a significant main effect of faller status for mean value measures (velocity, stride length, double support time and stride width) and for variability measures (swing time variability and stride length variability). Examination of individual gait parameters indicated that the multiple fallers walked more slowly, had shorter stride length, spent longer time in double support, had a wider support width and showed more variability in stride length and swing time (p<0.05). There was no significant interaction between gait condition and faller status for any of the gait variables. In conclusion, dual task activities adversely affect gait in cognitively impaired older people. Multiple fallers performed worse in each gait condition but the addition of a functional or cognitive secondary task provided no added benefit in discriminating fallers from non-fallers with cognitive impairment. Copyright © 2012 Elsevier B.V. All rights reserved.

  18. Measuring past glacier fluctuations from historic photographs geolocated using Structure from Motion

    NASA Astrophysics Data System (ADS)

    Vargo, L.; Anderson, B.; Horgan, H. J.; Mackintosh, A.; Lorrey, A.; Thornton, M.

    2017-12-01

    Quantifying glacier fluctuations is important for understanding how the cryosphere responds to climate variability and change. Photographs of past ice extents have become iconic images of climate change, but until now incorporating these images into quantitative estimates of glacier change has been problematic. We present a new method to quantitatively measure past glacier fluctuations from historic images. The method uses a large set of modern geolocated photographs and Structure from Motion (SfM) to calculate the camera parameters for the historic images, including the location from which they were taken. We initially apply this method to a small maritime New Zealand glacier (Brewster Glacier, 44°S, 2 km2), and quantify annual equilibrium line altitudes (ELAs) and length changes from historic oblique aerial photographs (1981 - 2017). Results show that Brewster has retreated 364 ± 12 m since 1981 and, using independent field measurements of terminus positions (2005 - 2014), we show that this SfM-derived length record accurately captures glacier change. We calculate the uncertainties associated with this method using known coordinates of bedrock features surrounding the glacier. Mean uncertainties in the ELA and length records are 7 m and 11 m, respectively. In addition to Brewster, 49 other New Zealand glaciers have been monitored by aerial photographs since 1978. However, the length records for these glaciers only include years of relative advance or retreat, and no length changes have been quantified. We will ultimately apply this method to all 50 glaciers, expanding the database of New Zealand glacier fluctuations that until now included only a few glaciers. This method can be further applied to any glacier with historic images, and can be used to measure past changes in glacier width, area, and surface elevation in addition to ELA and length.

  19. Spatial parameters of walking gait and footedness.

    PubMed

    Zverev, Y P

    2006-01-01

    The present study was undertaken to assess whether footedness has effects on selected spatial and angular parameters of able-bodied gait by evaluating footprints of young adults. A total of 112 males and 93 females were selected from among students and staff members of the University of Malawi using a simple random sampling method. Footedness of subjects was assessed by the Waterloo Footedness Questionnaire Revised. Gait at natural speed was recorded using the footprint method. The following spatial parameters of gait were derived from the inked footprint sequences of subjects: step and stride lengths, gait angle and base of gait. The anthropometric measurements taken were weight, height, leg and foot length, foot breadth, shoulder width, and hip and waist circumferences. The prevalence of right-, left- and mix-footedness in the whole sample of young Malawian adults was 81%, 8.3% and 10.7%, respectively. One-way analysis of variance did not reveal a statistically significant difference between footedness categories in the mean values of anthropometric measurements (p > 0.05 for all variables). Gender differences in step and stride length values were not statistically significant. Correction of these variables for stature did not change the trend. Males had significantly broader steps than females. Normalized values of base of gait had similar gender difference. The group means of step length and normalized step length of the right and left feet were similar, for males and females. There was a significant side difference in the gait angle in both gender groups of volunteers with higher mean values on the left side compared to the right one (t = 2.64, p < 0.05 for males, and t = 2.78, p < 0.05 for females). One-way analysis of variance did not demonstrate significant difference between footedness categories in the mean values of step length, gait angle, bilateral differences in step length and gait angle, stride length, gait base and normalized gait variables of male and female volunteers (p > 0.05 for all variables). The present study demonstrated that footedness does not affect spatial and angular parameters of walking gait.

  20. Correlation between Visible Length of the Iris and the Length of the Maxillary Central Incisor Using Digital Image Analysis- A Pilot Study.

    PubMed

    Rohini; Hemalatha; Chander, Gopi Naveen; Anitha, Kuttae Viswanathan

    2017-02-01

    Complete denture therapy is one such modality where science and art goes hand in hand. Selection of artificial teeth for completely edentulous patients is not easy in the absence of pre extraction records, because till date concrete guidelines do not exist. The purpose of this study was to determine if a correlation existed between the visible length of the iris and the length of the maxillary central incisor to potentially provide a guide for teeth selection. A total of 20 Indian dental students consented to participate in the pilot study. Standardized digital images of the face revealing the eyes and component of teeth on smiling was captured using a digital camera. The digital measurements of the visible iris length (medial aperture height, tangential to iris) and the length of the maxillary central incisor from the zenith to the incisal edge were analysed using Adobe Photoshop creative cloud software. The data was statistically evaluated and results were tabulated. Karl Pearson's Coefficient of Correlation was utilized to detect if any association existed between the two variables. The mean value of length of central incisor was 10.39 mm and the mean value of the visible length of iris was found to be 12.9 mm. A Pearson correlation analysis revealed an r-value <0.3 indicating minimal association between the two variables with a p-value >0.01 (.322). On inference, the correlation between the visible iris length and that of maxillary central incisor were unable to produce a strong positive statistical association. However, an association factor between the two has been obtained. Deduction of 2.5 mm from the dimension of visible iris length will help in attaining the length of artificial maxillary central incisor tooth.

  1. Low-resolution Australasian palaeoclimate records of the last 2000 years

    NASA Astrophysics Data System (ADS)

    Dixon, Bronwyn C.; Tyler, Jonathan J.; Lorrey, Andrew M.; Goodwin, Ian D.; Gergis, Joëlle; Drysdale, Russell N.

    2017-10-01

    Non-annually resolved palaeoclimate records in the Australasian region were compiled to facilitate investigations of decadal to centennial climate variability over the past 2000 years. A total of 675 lake and wetland, geomorphic, marine, and speleothem records were identified. The majority of records are located near population centres in southeast Australia, in New Zealand, and across the maritime continent, and there are few records from the arid regions of central and western Australia. Each record was assessed against a set of a priori criteria based on temporal resolution, record length, dating methods, and confidence in the proxy-climate relationship over the Common Era. A subset of 22 records met the criteria and were endorsed for subsequent analyses. Chronological uncertainty was the primary reason why records did not meet the selection criteria. New chronologies based on Bayesian techniques were constructed for the high-quality subset to ensure a consistent approach to age modelling and quantification of age uncertainties. The primary reasons for differences between published and reconstructed age-depth models were the consideration of the non-singular distribution of ages in calibrated 14C dates and the use of estimated autocorrelation between sampled depths as a constraint for changes in accumulation rate. Existing proxies and reconstruction techniques that successfully capture climate variability in the region show potential to address spatial gaps and expand the range of climate variables covering the last 2000 years in the Australasian region. Future palaeoclimate research and records in Australasia could be greatly improved through three main actions: (i) greater data availability through the public archiving of published records; (ii) thorough characterisation of proxy-climate relationships through site monitoring and climate sensitivity tests; and (iii) improvement of chronologies through core-top dating, inclusion of tephra layers where possible, and increased date density during the Common Era.

  2. A 650-year record of past summer temperatures from Pirin, Bulgaria tree-ring density

    NASA Astrophysics Data System (ADS)

    Meko, M. D.; Trouet, V.; Panayotov, M.; Frank, D. C.

    2017-12-01

    New proxy records of past climate provide valuable data essential to enhance spatial and temporal coverage of the global paleoclimate record - the context against which ongoing climate change and climate-model forcing is examined and evaluated. We present a new 650-year record of past summer temperatures in southeastern (SE) Europe derived from tree-ring maximum-latewood-density (MXD) data measured from Bosnian pine (Pinus heldreichii) growing at high elevations in the Pirin Mountains, Bulgaria (PRN). The PRN collection is well-replicated, with 64 trees contributing MXD series ranging in length from 113 to 865 years (median series length = 480 years) spanning the years 1143-2009. The PRN chronology shows a significant (p < 0.05) relationship with summer (JAS) temperatures across a broad geographical area of SE Europe, including the entire Balkan peninsula, southern Italy, and southwestern Anatolia. Our temperature reconstruction, produced by multiple regression utilizing lagged predictors and calibrated against Sofia, Bulgaria meteorological observations, explains nearly 60% of target variance and reveals variability across decadal, centennial, and longer timescales over the 1350-2009 reconstruction interval. Relative to the instrumental 1900-1980 mean, our record shows multidecadal cool anomalies spanning the first half of the 19th century and the late 17th century, and warm periods spanning the 18th century, 16th and early-to-mid 17th centuries, and late 14th to early 15th century. A comparison of the PRN reconstruction with existing reconstructions of Northern Hemisphere temperatures reveal intervals of asynchrony between local and hemisphere-scale decadal temperature variability, with marked asynchrony in the late 16th-early 17th centuries, and unprecedented asynchrony in the late 20th-to early 21st century.

  3. Resource utilization in home health care: results of a prospective study.

    PubMed

    Trisolini, M G; Thomas, C P; Cashman, S B; Payne, S M

    1994-01-01

    Resource utilization in home health care has become an issue of concern due to rising costs and recent initiatives to develop prospective payment systems for home health care. A number of issues remain unresolved for the development of prospective reimbursement in this sector, including the types of variables to be included as payment variables and appropriate measures of resource use. This study supplements previous work on home health case-mix by analyzing the factors affecting one aspect of resource use for skilled nursing visits--visit length--and explores the usefulness of several specially collected variables which are not routinely available in administrative records. A data collection instrument was developed with a focus group of skilled nurses, identifying a range of variables hypothesized to affect visit length. Five categories of variables were studied using multiple regression analysis: provider-related; patient's socio-economic status; patient's clinical status; patient's support services; and visit-specific. The final regression model identifies 9 variables which significantly affect visit time. Five of the 9 are visit-specific variables, a significant finding since these are not routinely collected. Case-mix systems which include visit time as a measure of resource use will need to investigate visit-specific variables, as this study indicates they could have the largest influence on visit time. Two other types of resources used in home health care, supplies and security drivers, were also investigated in less detail.

  4. Potential interactions among linguistic, autonomic, and motor factors in speech.

    PubMed

    Kleinow, Jennifer; Smith, Anne

    2006-05-01

    Though anecdotal reports link certain speech disorders to increases in autonomic arousal, few studies have described the relationship between arousal and speech processes. Additionally, it is unclear how increases in arousal may interact with other cognitive-linguistic processes to affect speech motor control. In this experiment we examine potential interactions between autonomic arousal, linguistic processing, and speech motor coordination in adults and children. Autonomic responses (heart rate, finger pulse volume, tonic skin conductance, and phasic skin conductance) were recorded simultaneously with upper and lower lip movements during speech. The lip aperture variability (LA variability index) across multiple repetitions of sentences that varied in length and syntactic complexity was calculated under low- and high-arousal conditions. High arousal conditions were elicited by performance of the Stroop color word task. Children had significantly higher lip aperture variability index values across all speaking tasks, indicating more variable speech motor coordination. Increases in syntactic complexity and utterance length were associated with increases in speech motor coordination variability in both speaker groups. There was a significant effect of Stroop task, which produced increases in autonomic arousal and increased speech motor variability in both adults and children. These results provide novel evidence that high arousal levels can influence speech motor control in both adults and children. (c) 2006 Wiley Periodicals, Inc.

  5. Predictive Variables of Half-Marathon Performance for Male Runners

    PubMed Central

    Gómez-Molina, Josué; Ogueta-Alday, Ana; Camara, Jesus; Stickley, Christoper; Rodríguez-Marroyo, José A.; García-López, Juan

    2017-01-01

    The aims of this study were to establish and validate various predictive equations of half-marathon performance. Seventy-eight half-marathon male runners participated in two different phases. Phase 1 (n = 48) was used to establish the equations for estimating half-marathon performance, and Phase 2 (n = 30) to validate these equations. Apart from half-marathon performance, training-related and anthropometric variables were recorded, and an incremental test on a treadmill was performed, in which physiological (VO2max, speed at the anaerobic threshold, peak speed) and biomechanical variables (contact and flight times, step length and step rate) were registered. In Phase 1, half-marathon performance could be predicted to 90.3% by variables related to training and anthropometry (Equation 1), 94.9% by physiological variables (Equation 2), 93.7% by biomechanical parameters (Equation 3) and 96.2% by a general equation (Equation 4). Using these equations, in Phase 2 the predicted time was significantly correlated with performance (r = 0.78, 0.92, 0.90 and 0.95, respectively). The proposed equations and their validation showed a high prediction of half-marathon performance in long distance male runners, considered from different approaches. Furthermore, they improved the prediction performance of previous studies, which makes them a highly practical application in the field of training and performance. Key points The present study obtained four equations involving anthropometric, training, physiological and biomechanical variables to estimate half-marathon performance. These equations were validated in a different population, demonstrating narrows ranges of prediction than previous studies and also their consistency. As a novelty, some biomechanical variables (i.e. step length and step rate at RCT, and maximal step length) have been related to half-marathon performance. PMID:28630571

  6. Aortoiliac morphologic correlations in aneurysms undergoing endovascular repair.

    PubMed

    Ouriel, Kenneth; Tanquilut, Eugene; Greenberg, Roy K; Walker, Esteban

    2003-08-01

    The feasibility of endovascular aneurysm repair depends on morphologic characteristics of the aortoiliac segment. Knowledge of such characteristics is relevant to safe deployment of a particular device in a single patient and to development of new devices for use in patients with a broader spectrum of anatomic variations. We evaluated findings on computed tomography scans for 277 patients being considered for endovascular aneurysm repair. Aortic neck length and angulation estimates were generated with three-dimensional trigonometry. Specific centerline points were recorded, corresponding to the aorta at the celiac axis, lowest renal artery, cranial aspect of the aneurysm sac, aortic terminus, right hypogastric artery origin, and left hypogastric origin. Aortic neck thrombus and calcium content were recorded, and neck conicity was calculated in degrees. Statistical analysis was performed with the Spearman rank correlation. Data are expressed as median and interquartile range. Median diameter of the aneurysms was 52 mm (interquartile range, 48-59 mm) in minor axis and 56 mm (interquartile range, 51-64 mm) in major axis, and median length was 88 mm (interquartile range, 74-103 mm). Median proximal aortic neck diameter was 26 mm (interquartile range, 22-29 mm), and median neck length was 30 mm (interquartile range, 18-45 mm). The common iliac arteries were similar in diameter (right artery, 16 mm [interquartile range, 13-20 mm]; left artery, 15 mm [interquartile range, 11-18 mm]) and length (right, 59 mm [interquartile range, 50-69 mm]; left, 60 mm [interquartile range, 49-70 mm]). Median angulation of the infrarenal aortic neck was 40 degrees (interquartile range, 29-51 degrees), and median angulation of the suprarenal segment was 45 degrees (interquartile range, 36-57 degrees). By gender, sac diameter, proximal neck diameter, and iliac artery diameter were significantly larger in men. Significant linear associations were identified between sac diameter and sac length, neck angulation, and iliac artery diameter. As the length of the aneurysm sac increased the proximal aortic neck length decreased. Conversely, as the sac length decreased sac eccentricity increased. Mural thrombus content within the neck increased with increasing neck diameter. There is considerable variability in aortoiliac morphologic parameters. Significant associations were found between various morphologic variables, links that are presumably related to a shared pathogenesis for aberration in aortoiliac diameter, length, and angulation. Ultimately this information can be used to develop new endovascular devices with broader applicability and improved long-term results.

  7. Validity of (Ultra-)Short Recordings for Heart Rate Variability Measurements

    PubMed Central

    Munoz, M. Loretto; van Roon, Arie; Riese, Harriëtte; Thio, Chris; Oostenbroek, Emma; Westrik, Iris; de Geus, Eco J. C.; Gansevoort, Ron; Lefrandt, Joop

    2015-01-01

    Objectives In order to investigate the applicability of routine 10s electrocardiogram (ECG) recordings for time-domain heart rate variability (HRV) calculation we explored to what extent these (ultra-)short recordings capture the “actual” HRV. Methods The standard deviation of normal-to-normal intervals (SDNN) and the root mean square of successive differences (RMSSD) were measured in 3,387 adults. SDNN and RMSSD were assessed from (ultra)short recordings of 10s(3x), 30s, and 120s and compared to 240s–300s (gold standard) measurements. Pearson’s correlation coefficients (r), Bland-Altman 95% limits of agreement and Cohen’s d statistics were used as agreement analysis techniques. Results Agreement between the separate 10s recordings and the 240s-300s recording was already substantial (r = 0.758–0.764/Bias = 0.398–0.416/d = 0.855–0.894 for SDNN; r = 0.853–0.862/Bias = 0.079–0.096/d = 0.150–0.171 for RMSSD), and improved further when three 10s periods were averaged (r = 0.863/Bias = 0.406/d = 0.874 for SDNN; r = 0.941/Bias = 0.088/d = 0.167 for RMSSD). Agreement increased with recording length and reached near perfect agreement at 120s (r = 0.956/Bias = 0.064/d = 0.137 for SDNN; r = 0.986/Bias = 0.014/d = 0.027 for RMSSD). For all recording lengths and agreement measures, RMSSD outperformed SDNN. Conclusions Our results confirm that it is unnecessary to use recordings longer than 120s to obtain accurate measures of RMSSD and SDNN in the time domain. Even a single 10s (standard ECG) recording yields a valid RMSSD measurement, although an average over multiple 10s ECGs is preferable. For SDNN we would recommend either 30s or multiple 10s ECGs. Future research projects using time-domain HRV parameters, e.g. genetic epidemiological studies, could calculate HRV from (ultra-)short ECGs enabling such projects to be performed at a large scale. PMID:26414314

  8. Radiation dose exposure in patients affected by lymphoma undergoing repeat CT examinations: how to manage the radiation dose variability.

    PubMed

    Paolicchi, Fabio; Bastiani, Luca; Guido, Davide; Dore, Antonio; Aringhieri, Giacomo; Caramella, Davide

    2018-03-01

    To assess the variability of radiation dose exposure in patients affected by lymphoma undergoing repeat CT (computed tomography) examinations and to evaluate the influence of different scan parameters on the overall radiation dose. A series of 34 patients (12 men and 22 women with a median age of 34.4 years) with lymphoma, after the initial staging CT underwent repeat follow-up CT examinations. For each patient and each repeat examination, age, sex, use of AEC system (Automated Exposure Control, i.e. current modulation), scan length, kV value, number of acquired scans (i.e. number of phases), abdominal size diameter and dose length product (DLP) were recorded. The radiation dose of just one venous phase was singled out from the DLP of the entire examination. All scan data were retrieved by our PACS (Picture Archiving and Communication System) by means of a dose monitoring software. Among the variables we considered, no significant difference of radiation dose was observed among patients of different ages nor concerning tube voltage. On the contrary the dose delivered to the patients varied depending on sex, scan length and usage of AEC. No significant difference was observed depending on the behaviour of technologists, while radiologists' choices had indirectly an impact on the radiation dose due to the different number of scans requested by each of them. Our results demonstrate that patients affected by lymphoma who undergo repeat whole body CT scanning may receive unnecessary overexposure. We quantified and analyzed the most relevant variables in order to provide a useful tool to manage properly CT dose variability, estimating the amount of additional radiation dose for every single significant variable. Additional scans, incorrect scan length and incorrect usage of AEC system are the most relevant cause of patient radiation exposure.

  9. Methods for estimating the magnitude and frequency of peak discharges of rural, unregulated streams in Virginia

    USGS Publications Warehouse

    Bisese, James A.

    1995-01-01

    Methods are presented for estimating the peak discharges of rural, unregulated streams in Virginia. A Pearson Type III distribution is fitted to the logarithms of the unregulated annual peak-discharge records from 363 stream-gaging stations in Virginia to estimate the peak discharge at these stations for recurrence intervals of 2 to 500 years. Peak-discharge characteristics for 284 unregulated stations are divided into eight regions based on physiographic province, and regressed on basin characteristics, including drainage area, main channel length, main channel slope, mean basin elevation, percentage of forest cover, mean annual precipitation, and maximum rainfall intensity. Regression equations for each region are computed by use of the generalized least-squares method, which accounts for spatial and temporal correlation between nearby gaging stations. This regression technique weights the significance of each station to the regional equation based on the length of records collected at each cation, the correlation between annual peak discharges among the stations, and the standard deviation of the annual peak discharge for each station.Drainage area proved to be the only significant explanatory variable in four regions, while other regions have as many as three significant variables. Standard errors of the regression equations range from 30 to 80 percent. Alternate equations using drainage area only are provided for the five regions with more than one significant explanatory variable.Methods and sample computations are provided to estimate peak discharges at gaged and engaged sites in Virginia for recurrence intervals of 2, 5, 10, 25, 50, 100, 200, and 500 years, and to adjust the regression estimates for sites on gaged streams where nearby gaging-station records are available.

  10. Leukocytes as risk markers for cardiovascular disease in adolescents: association with birth characteristics, nutritional status and biochemical tests

    PubMed Central

    do Prado, Pedro Paulo; de Faria, Franciane Rocha; de Faria, Eliane Rodrigues; Franceschini, Sylvia do Carmo Castro; Priore, Silvia Eloiza

    2016-01-01

    Abstract Objective: To evaluate the correlation between the number of leukocytes and cardiovascular risks associated with birth characteristics, nutritional status and biochemical tests. Methods: Cross-sectional study developed with 475 adolescents, born between 1992 and 2001, in the municipality of Viçosa (MG). Maternal medical records were analyzed in the hospital units, and the following was recorded: birth weight and length, head circumference, chest circumference, Apgar score, gestational age. In adolescents, body mass index, skinfold thickness, body composition, blood count, biochemical tests and clinical variables were also assessed. The statistical analyses was carried out using Statistical Package for Social Sciences (SPSS) version 20.0 and Data Analysis and Statistical Software (STATA) with Kruskal–Wallis, Mann–Whitney, chi-square or Fisher's exact tests and Linear Regression. Significance level was set at α<0.05. The study was approved by the Research Ethics Committee of UFV for studies with human subjects. Results: Weight and birth length, head and chest circumference were higher among boys. In adolescents, the number of leukocytes was higher in individuals with excess weight and body fat and high adiposity index, waist-to-height ratio and waist circumference. Only altered triglycerides showed differences between leukocyte medians. Regardless of the anthropometric variable of the final regression model, the stage of adolescence, number of platelets, eosinophils, monocytes and lymphocytes were associated with the increase in leukocytes. Conclusions: The birth variables were not associated with changes in leukocyte numbers, whereas the anthropometric variables were good indicators for a higher leukocyte count, regardless of the stage of adolescence and gender. PMID:26572104

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Post, Wilfred M; King, Anthony Wayne; Dragoni, Danilo

    Many parameters in terrestrial biogeochemical models are inherently uncertain, leading to uncertainty in predictions of key carbon cycle variables. At observation sites, this uncertainty can be quantified by applying model-data fusion techniques to estimate model parameters using eddy covariance observations and associated biometric data sets as constraints. Uncertainty is reduced as data records become longer and different types of observations are added. We estimate parametric and associated predictive uncertainty at the Morgan Monroe State Forest in Indiana, USA. Parameters in the Local Terrestrial Ecosystem Carbon (LoTEC) are estimated using both synthetic and actual constraints. These model parameters and uncertainties aremore » then used to make predictions of carbon flux for up to 20 years. We find a strong dependence of both parametric and prediction uncertainty on the length of the data record used in the model-data fusion. In this model framework, this dependence is strongly reduced as the data record length increases beyond 5 years. If synthetic initial biomass pool constraints with realistic uncertainties are included in the model-data fusion, prediction uncertainty is reduced by more than 25% when constraining flux records are less than 3 years. If synthetic annual aboveground woody biomass increment constraints are also included, uncertainty is similarly reduced by an additional 25%. When actual observed eddy covariance data are used as constraints, there is still a strong dependence of parameter and prediction uncertainty on data record length, but the results are harder to interpret because of the inability of LoTEC to reproduce observed interannual variations and the confounding effects of model structural error.« less

  12. Linked Records of Children with Traumatic Brain Injury. Probabilistic Linkage without Use of Protected Health Information.

    PubMed

    Bennett, T D; Dean, J M; Keenan, H T; McGlincy, M H; Thomas, A M; Cook, L J

    2015-01-01

    Record linkage may create powerful datasets with which investigators can conduct comparative effectiveness studies evaluating the impact of tests or interventions on health. All linkages of health care data files to date have used protected health information (PHI) in their linkage variables. A technique to link datasets without using PHI would be advantageous both to preserve privacy and to increase the number of potential linkages. We applied probabilistic linkage to records of injured children in the National Trauma Data Bank (NTDB, N = 156,357) and the Pediatric Health Information Systems (PHIS, N = 104,049) databases from 2007 to 2010. 49 match variables without PHI were used, many of them administrative variables and indicators for procedures recorded as International Classification of Diseases, 9th revision, Clinical Modification codes. We validated the accuracy of the linkage using identified data from a single center that submits to both databases. We accurately linked the PHIS and NTDB records for 69% of children with any injury, and 88% of those with severe traumatic brain injury eligible for a study of intervention effectiveness (positive predictive value of 98%, specificity of 99.99%). Accurate linkage was associated with longer lengths of stay, more severe injuries, and multiple injuries. In populations with substantial illness or injury severity, accurate record linkage may be possible in the absence of PHI. This methodology may enable linkages and, in turn, comparative effectiveness studies that would be unlikely or impossible otherwise.

  13. To the Greatest Lengths: Al Qaeda, Proximity and Recruitment Risk

    DTIC Science & Technology

    2010-12-01

    activity (Boba, 2005, pp. 218–219). On the complex end of this spectrum, density mapping uses mathematical formulas to determine degrees of criminal...area. These calculations "combines actuarial risk prediction with environmental criminology to assign risk values to places according to their...translated records, and the compilation of distance variables are correct. 46 2. Model Mathematically , the formula for this test is

  14. Effect of private versus emergency medical systems transportation in motor vehicle accident victims: Trauma Center Experience in Saudi Arabia.

    PubMed

    Alshahrani, Mohammed S

    2017-01-01

    To assess the effect of the mode of transportation of trauma patients (emergency medical service [EMS] vs. non-EMS) on their final clinical outcome in terms of mortality and length of hospital stay. A retrospective study included all patients who were involved in motor vehicle crashes, and who were transferred immediately to an emergency department of a trauma care center from December 2008 to December 2012. Patients were classified into two groups: those brought through EMS and those brought by non-EMS (private transport). Information on demographic characteristics including age and gender was recorded and medical data such as blood pressure, pulse, oxygen saturation, temperature, initial Glasgow Coma Score (GCS), saturation, temperature, initial Glasgow Coma Score (GCS), injury severity score (ISS), and final outcome (discharged or expired) were obtained. Descriptive statistics, mean and standard deviation (SD) were computed for continuous variables and statistical significance was tested by t -test or Mann-Whitney U-test. Categorical variables were described by frequency distribution and percentages; Chi-square or Fisher's exact test as appropriate were employed to test for statistical significance. Logistics regression was performed with mortality as dependent variable and mode of transport and all demographic and prehospital variables as independent variables. A general linear model analysis was performed to test whether the mode of transport was significant to length of hospital stay in EMS and non-EMS clients. Out of 308 patients identified during the study period, 232 were transported through EMS and 76 through non-EMS. The two groups were similar with regard to mortality and length of stay. The crude mortality rate was 30.6% (95% confidence interval [CI]: 24.64-36.53) in the EMS group and 28.9% (95% CI: 18.44-38.76) in the non-EMS group ( p = 0.785). The average length of hospital stay was 9 days (interquartile range [IQR] = 8, 95% CI: 7.3-10.1) for the EMS group and 8 days (IQR = 9.5, 95% CI: 6.7-10.9) for the non-EMS group ( p = 0.803). Multivariate analysis showed that of the study variables, only the injury severity score (ISS) and Glasgow coma score (GCS) were significant to mortality ( p < 0.01), and GCS was more significant to the length of hospital stay ( p < 0.01). There was no significant difference between the EMS and non-EMS groups as they relate to mortality and length of stay in hospital. However, the mortality and length of hospital stay was statistically significant to ISS and GCS.

  15. Vocal tract length and acoustics of vocalization in the domestic dog (Canis familiaris).

    PubMed

    Riede, T; Fitch, T

    1999-10-01

    The physical nature of the vocal tract results in the production of formants during vocalisation. In some animals (including humans), receivers can derive information (such as body size) about sender characteristics on the basis of formant characteristics. Domestication and selective breeding have resulted in a high variability in head size and shape in the dog (Canis familiaris), suggesting that there might be large differences in the vocal tract length, which could cause formant behaviour to affect interbreed communication. Lateral radiographs were made of dogs from several breeds ranging in size from a Yorkshire terrier (2.5 kg) to a German shepherd (50 kg) and were used to measure vocal tract length. In addition, we recorded an acoustic signal (growling) from some dogs. Significant correlations were found between vocal tract length, body mass and formant dispersion, suggesting that formant dispersion can deliver information about the body size of the vocalizer. Because of the low correlation between vocal tract length and the first formant, we predict a non-uniform vocal tract shape.

  16. Birth dimensions in Melanesian and Indian Fijians and their relationships with maternal and socio-economic factors.

    PubMed

    Clegg, E J; Clegg, S D

    1989-01-01

    Fifty-nine Melanesian (MF) and 39 Indian (IF) Fijian full-term newborns were studied within 5 days of birth. Dimensions recorded included birthweight, length, crown-rump length, head circumference, upper limb length, bycondylar humeral and femoral diameters and four skinfolds (triceps, subscapular, suprailiac and thigh). Data from previous pregnancies of the presenting newborns' mothers were added to presenting birthweights, giving a total of 160 MF and 84 IF birthweights. In all birthweight and linear dimensions MFs were the bigger. Sex differences were significant in respect only of head circumference and the two bicondylar diameters. Multiple regression analysis showed dimensions in MF newborns to have few significant relationships with the maternal and socio-economic variables of age, parity, stature and years of education, but IFs had many more significant relationships. When covariance correction was made for the significant maternal and socio-economic variables (maternal age and parity) little effect on racial differences was seen. All linear dimensions except length could be subsumed into birthweight. MFs had greater triceps and subscapular skinfold thicknesses than IFs, a difference which was not much changed by covariance correction for significant maternal and socio-economic variables (maternal stature and years of education). Measurements of shape, expressed as ratios of linear dimensions, showed few racial differences but males had relatively broader limbs. For upper limb shape only, this difference was maintained after covariance correction for significant maternal and socio-economic variables (parity, stature and education). The greater size of MF infants at birth is associated with lower peri- and neonatal death rates. However this advantage is reversed during the remainder of the first year of life. It is suggested that better standards of infant care among IFs are responsible for this change.

  17. Similarities and differences among half-marathon runners according to their performance level

    PubMed Central

    Morante, Juan Carlos; Gómez-Molina, Josué; García-López, Juan

    2018-01-01

    This study aimed to identify the similarities and differences among half-marathon runners in relation to their performance level. Forty-eight male runners were classified into 4 groups according to their performance level in a half-marathon (min): Group 1 (n = 11, < 70 min), Group 2 (n = 13, < 80 min), Group 3 (n = 13, < 90 min), Group 4 (n = 11, < 105 min). In two separate sessions, training-related, anthropometric, physiological, foot strike pattern and spatio-temporal variables were recorded. Significant differences (p<0.05) between groups (ES = 0.55–3.16) and correlations with performance were obtained (r = 0.34–0.92) in training-related (experience and running distance per week), anthropometric (mass, body mass index and sum of 6 skinfolds), physiological (VO2max, RCT and running economy), foot strike pattern and spatio-temporal variables (contact time, step rate and length). At standardized submaximal speeds (11, 13 and 15 km·h-1), no significant differences between groups were observed in step rate and length, neither in contact time when foot strike pattern was taken into account. In conclusion, apart from training-related, anthropometric and physiological variables, foot strike pattern and step length were the only biomechanical variables sensitive to half-marathon performance, which are essential to achieve high running speeds. However, when foot strike pattern and running speeds were controlled (submaximal test), the spatio-temporal variables were similar. This indicates that foot strike pattern and running speed are responsible for spatio-temporal differences among runners of different performance level. PMID:29364940

  18. The Sensetivity of Flood Frequency Analysis on Record Length in Continuous United States

    NASA Astrophysics Data System (ADS)

    Hu, L.; Nikolopoulos, E. I.; Anagnostou, E. N.

    2017-12-01

    In flood frequency analysis (FFA), sufficiently long data series are important to get more reliable results. Compared to return periods of interest, at-site FFA usually needs large data sets. Generally, the precision of at site estimators and time-sampling errors are associated with the length of a gauged record. In this work, we quantify the difference with various record lengths. we use generalized extreme value (GEV) and Log Pearson type III (LP3), two traditional methods on annual maximum stream flows to undertake FFA, and propose quantitative ways, relative difference in median and interquartile range (IQR) to compare the flood frequency performances on different record length from selected 350 USGS gauges, which have more than 70 years record length in Continuous United States. Also, we group those gauges into different regions separately based on hydrological unit map and discuss the geometry impacts. The results indicate that long record length can avoid imposing an upper limit on the degree of sophistication. Working with relatively longer record length may lead accurate results than working with shorter record length. Furthermore, the influence of hydrologic unites for the watershed boundary dataset on those gauges also be presented. The California region is the most sensitive to record length, while gauges in the east perform steady.

  19. The precision of locomotor odometry in humans.

    PubMed

    Durgin, Frank H; Akagi, Mikio; Gallistel, Charles R; Haiken, Woody

    2009-03-01

    Two experiments measured the human ability to reproduce locomotor distances of 4.6-100 m without visual feedback and compared distance production with time production. Subjects were not permitted to count steps. It was found that the precision of human odometry follows Weber's law that variability is proportional to distance. The coefficients of variation for distance production were much lower than those measured for time production for similar durations. Gait parameters recorded during the task (average step length and step frequency) were found to be even less variable suggesting that step integration could be the basis for non-visual human odometry.

  20. Detection time for global and regional sea level trends and accelerations

    NASA Astrophysics Data System (ADS)

    Jordà, G.

    2014-10-01

    Many studies analyze trends on sea level data with the underlying purpose of finding indications of a long-term change that could be interpreted as the signature of anthropogenic climate change. The identification of a long-term trend is a signal-to-noise problem where the natural variability (the "noise") can mask the long-term trend (the "signal"). The signal-to-noise ratio depends on the magnitude of the long-term trend, on the magnitude of the natural variability, and on the length of the record, as the climate noise is larger when averaged over short time scales and becomes smaller over longer averaging periods. In this paper, we evaluate the time required to detect centennial sea level linear trends and accelerations at global and regional scales. Using model results and tide gauge observations, we find that the averaged detection time for a centennial linear trend is 87.9, 76.0, 59.3, 40.3, and 25.2 years for trends of 0.5, 1.0, 2.0, 5.0, and 10.0 mm/yr, respectively. However, in regions with large decadal variations like the Gulf Stream or the Circumpolar current, these values can increase up to a 50%. The spatial pattern of the detection time for sea level accelerations is almost identical. The main difference is that the length of the records has to be about 40-60 years longer to detect an acceleration than to detect a linear trend leading to an equivalent change after 100 years. Finally, we have used a new sea level reconstruction, which provides a more accurate representation of interannual variability for the last century in order to estimate the detection time for global mean sea level trends and accelerations. Our results suggest that the signature of natural variability in a 30 year global mean sea level record would be less than 1 mm/yr. Therefore, at least 2.2 mm/yr of the recent sea level trend estimated by altimetry cannot be attributed to natural multidecadal variability. This article was corrected on 19 NOV 2014. See the end of the full text for details.

  1. Reconstructing the 11-year solar cycle length from cosmogenic radionuclides for the last 600 years

    NASA Astrophysics Data System (ADS)

    Nilsson, Emma; Adolphi, Florian; Mekhaldi, Florian; Muscheler, Raimund

    2017-04-01

    The cyclic behavior of the solar magnetic field has been known for centuries and the 11-year solar cycle is one of the most important features directly visible on the solar disc. Using sunspot records it is evident that the length of this cycle is variable. A hypothesis of an inverse relationship between the average solar activity level and the solar cycle length has been put forward (e.g. Friis-Christensen & Lassen, 1991), indicating longer solar cycles during periods of low solar activity and vice versa. So far, studies of the behavior of the 11-year solar cycle have largely been limited for the last 4 centuries where observational sunspot data are available. However, cosmogenic radionuclides, such as 10Be and 14C from ice cores and tree rings allow an assessment of the strength of the open solar magnetic field due to its shielding influence on galactic cosmic rays in the heliosphere. Similarly, very strong solar storms can leave their imprint in cosmogenic radionuclide records via solar proton-induced direct production of cosmogenic radionuclides in the Earth atmosphere. Here, we test the hypothesis of an inverse relationship between solar cycle length and the longer-term solar activity level by using cosmogenic radionuclide records as a proxy for solar activity. Our results for the last six centuries suggest significant solar cycle length variations that could exceed the range directly inferred from sunspot records. We discuss the occurrence of SPEs within the 11-year solar cycle from a radionuclide perspective, specifically the largest one known yet, at AD 774-5 (Mekhaldi et al., 2015). References: Friis-Christensen, E. & Lassen, K. Length of the solar-cycle - An indicator of solar activity closely associated with climate. Science 254, 698-700, doi:10.1126/science.254.5032.698 (1991). Mekhaldi, F., Muscheler, R., Adolphi, F., Aldahan, A., Beer, J., McConnell, J. R., Possnert, G., Sigl, M., Svensson, A., Synal, H. A., Welten, K. C. & Woodruff, T. E. Multiradionuclide evidence for the solar origin of the cosmic-ray events of AD 774/5 and 993/4. Nature Communications 6: 8, doi:10.1038/ncomms9611 (2015).

  2. Sources and Impacts of Modeled and Observed Low-Frequency Climate Variability

    NASA Astrophysics Data System (ADS)

    Parsons, Luke Alexander

    Here we analyze climate variability using instrumental, paleoclimate (proxy), and the latest climate model data to understand more about the sources and impacts of low-frequency climate variability. Understanding the drivers of climate variability at interannual to century timescales is important for studies of climate change, including analyses of detection and attribution of climate change impacts. Additionally, correctly modeling the sources and impacts of variability is key to the simulation of abrupt change (Alley et al., 2003) and extended drought (Seager et al., 2005; Pelletier and Turcotte, 1997; Ault et al., 2014). In Appendix A, we employ an Earth system model (GFDL-ESM2M) simulation to study the impacts of a weakening of the Atlantic meridional overturning circulation (AMOC) on the climate of the American Tropics. The AMOC drives some degree of local and global internal low-frequency climate variability (Manabe and Stouffer, 1995; Thornalley et al., 2009) and helps control the position of the tropical rainfall belt (Zhang and Delworth, 2005). We find that a major weakening of the AMOC can cause large-scale temperature, precipitation, and carbon storage changes in Central and South America. Our results suggest that possible future changes in AMOC strength alone will not be sufficient to drive a large-scale dieback of the Amazonian forest, but this key natural ecosystem is sensitive to dry-season length and timing of rainfall (Parsons et al., 2014). In Appendix B, we compare a paleoclimate record of precipitation variability in the Peruvian Amazon to climate model precipitation variability. The paleoclimate (Lake Limon) record indicates that precipitation variability in western Amazonia is 'red' (i.e., increasing variability with timescale). By contrast, most state-of-the-art climate models indicate precipitation variability in this region is nearly 'white' (i.e., equally variability across timescales). This paleo-model disagreement in the overall structure of the variance spectrum has important consequences for the probability of multi-year drought. Our lake record suggests there is a significant background threat of multi-year, and even decade-length, drought in western Amazonia, whereas climate model simulations indicate most droughts likely last no longer than one to three years. These findings suggest climate models may underestimate the future risk of extended drought in this important region. In Appendix C, we expand our analysis of climate variability beyond South America. We use observations, well-constrained tropical paleoclimate, and Earth system model data to examine the overall shape of the climate spectrum across interannual to century frequencies. We find a general agreement among observations and models that temperature variability increases with timescale across most of the globe outside the tropics. However, as compared to paleoclimate records, climate models generate too little low-frequency variability in the tropics (e.g., Laepple and Huybers, 2014). When we compare the shape of the simulated climate spectrum to the spectrum of a simple autoregressive process, we find much of the modeled surface temperature variability in the tropics could be explained by ocean smoothing of weather noise. Importantly, modeled precipitation tends to be similar to white noise across much of the globe. By contrast, paleoclimate records of various types from around the globe indicate that both temperature and precipitation variability should experience much more low-frequency variability than a simple autoregressive or white-noise process. In summary, state-of-the-art climate models generate some degree of dynamically driven low-frequency climate variability, especially at high latitudes. However, the latest climate models, observations, and paleoclimate data provide us with drastically different pictures of the background climate system and its associated risks. This research has important consequences for improving how we simulate climate extremes as we enter a warmer (and often drier) world in the coming centuries; if climate models underestimate low-frequency variability, we will underestimate the risk of future abrupt change and extreme events, such as megadroughts.

  3. Neonatal stretched penile length: relationship with gestational maturity and anthropometric parameters at birth.

    PubMed

    Bhakhri, Bhanu Kiran; Meena, Shyam Sundar; Rawat, Mayank; Datta, Vikram

    2015-02-01

    It is inappropriate to use universal cut-off points to interpret stretched penile length (SPL) measurements in newborns with variable body dimensions. To assess neonatal SPL on the basis of gestational maturity and anthropometric parameters at birth. A cross-sectional observational study of SPL was conducted on stable newborns at a referral teaching hospital in north India between January and June 2012. Gestational maturity, SPL and anthropometric parameters (weight, length, head circumference and foot length) were recorded within 24 hours of birth. Variation of SPL in relation to gestational age and anthropometric parameters were evaluated using multiple linear regression models. The equation using lower confidence limits of 95% confidence intervals for the correlation coefficients provides cut-off points to define a small penis. Data from 1249 newborns demonstrated that penile growth follows the pattern of increase in body dimensions in newborns. SPL can be predicted best in relation to body and foot length taken together. SPL should be interpreted in relation to anthropometric parameters in newborns, particularly body and foot length.

  4. Investigation of n-Alkane Distributions in Modern Plant Litter from Hawaii wetlands: a potential proxy for past vegetation and hydroclimate changes?

    NASA Astrophysics Data System (ADS)

    Massa, C.; Beilman, D. W.; Nichols, J. E.; Elison Timm, O.

    2016-12-01

    Holocene peat deposits from the Hawaiian Islands provide a unique opportunity to resolve millennial to centennial-scale climate variability over the central Pacific region, where data remain scarce. Because both extratropical and tropical modes of climate variability have a strong influence on modern rainfall over the archipelago, hydroclimate proxies from peat would provide valuable information about past Pacific climate changes. The few terrestrial records studied, based on pollen or leaf wax biomarkers, showed evidence for substantial vegetation changes that have been linked to a drying trend over the Holocene. Leaf wax n-alkanes, as well as their stable isotopic compositions (δ13C and δD), are indeed increasingly used to reconstruct past hydroclimate conditions. The interpretation of n-alkanes as biomarkers requires however a thorough knowledge of their distribution in modern plants that contribute to sediments, but in Hawaii the modern vegetation is understudied compared to proxy applications. Here we report results from a preliminary investigation of n-alkanes distributions in dominant modern plant litter collected at a bog site at the summit of the Waianae mountains on the Island of Oahu. We compared n-alkane distributions among species and plant groups in order to test whether taxa or plant functional types (mosses, ferns, woody plants, and sedges) can be discriminated from their n-alkane profiles. Results showed that general plant groups were difficult to distinguish based on individual n-alkanes abundances, chain lengths, or ratios. At the species level, the sedge Machaerina augustifolia, was largely dominated by n-C29 ( 60%), suggesting some chain lengths could be useful as proxies for identifying the contribution of sedges to sedimentary records. Woody plant average chain length was highly variable but overall was not shorter (even slightly higher) than in other terrestrial plants, as it is often assumed. A sedimentary profile from this site shows variation and an overall decrease in n-alkane chain length over the Holocene, but patterns across common modern plants suggest that caution should be exercised when ascribing n-alkane distribution parameters to a specific group of tropical vegetation.

  5. Abnormal gait pattern emerges during curved trajectories in high-functioning Parkinsonian patients walking in line at normal speed

    PubMed Central

    Godi, Marco; Giardini, Marica; Arcolin, Ilaria; Nardone, Antonio; Giordano, Andrea; Schieppati, Marco

    2018-01-01

    Background Several patients with Parkinson´s disease (PD) can walk normally along straight trajectories, and impairment in their stride length and cadence may not be easily discernible. Do obvious abnormalities occur in these high-functioning patients when more challenging trajectories are travelled, such as circular paths, which normally implicate a graded modulation in the duration of the interlimb gait cycle phases? Methods We compared a cohort of well-treated mildly to moderately affected PD patients to a group of age-matched healthy subjects (HS), by deliberately including HS spontaneously walking at the same speed of the patients with PD. All participants performed, in random order: linear and circular walking (clockwise and counter-clockwise) at self-selected speed. By means of pressure-sensitive insoles, we recorded walking speed, cadence, duration of single support, double support, swing phase, and stride time. Stride length-cadence relationships were built for linear and curved walking. Stride-to-stride variability of temporal gait parameters was also estimated. Results Walking speed, cadence or stride length were not different between PD and HS during linear walking. Speed, cadence and stride length diminished during curved walking in both groups, stride length more in PD than HS. In PD compared to HS, the stride length-cadence relationship was altered during curved walking. Duration of the double-support phase was also increased during curved walking, as was variability of the single support, swing phase and double support phase. Conclusion The spatio-temporal gait pattern and variability are significantly modified in well-treated, high-functioning patients with PD walking along circular trajectories, even when they exhibit no changes in speed in straight-line walking. The increased variability of the gait phases during curved walking is an identifying characteristic of PD. We discuss our findings in term of interplay between control of balance and of locomotor progression: the former is challenged by curved trajectories even in high-functioning patients, while the latter may not be critically affected. PMID:29750815

  6. Geostatistical Analysis of Mesoscale Spatial Variability and Error in SeaWiFS and MODIS/Aqua Global Ocean Color Data

    NASA Astrophysics Data System (ADS)

    Glover, David M.; Doney, Scott C.; Oestreich, William K.; Tullo, Alisdair W.

    2018-01-01

    Mesoscale (10-300 km, weeks to months) physical variability strongly modulates the structure and dynamics of planktonic marine ecosystems via both turbulent advection and environmental impacts upon biological rates. Using structure function analysis (geostatistics), we quantify the mesoscale biological signals within global 13 year SeaWiFS (1998-2010) and 8 year MODIS/Aqua (2003-2010) chlorophyll a ocean color data (Level-3, 9 km resolution). We present geographical distributions, seasonality, and interannual variability of key geostatistical parameters: unresolved variability or noise, resolved variability, and spatial range. Resolved variability is nearly identical for both instruments, indicating that geostatistical techniques isolate a robust measure of biophysical mesoscale variability largely independent of measurement platform. In contrast, unresolved variability in MODIS/Aqua is substantially lower than in SeaWiFS, especially in oligotrophic waters where previous analysis identified a problem for the SeaWiFS instrument likely due to sensor noise characteristics. Both records exhibit a statistically significant relationship between resolved mesoscale variability and the low-pass filtered chlorophyll field horizontal gradient magnitude, consistent with physical stirring acting on large-scale gradient as an important factor supporting observed mesoscale variability. Comparable horizontal length scales for variability are found from tracer-based scaling arguments and geostatistical decorrelation. Regional variations between these length scales may reflect scale dependence of biological mechanisms that also create variability directly at the mesoscale, for example, enhanced net phytoplankton growth in coastal and frontal upwelling and convective mixing regions. Global estimates of mesoscale biophysical variability provide an improved basis for evaluating higher resolution, coupled ecosystem-ocean general circulation models, and data assimilation.

  7. The spinal control of locomotion and step-to-step variability in left-right symmetry from slow to moderate speeds

    PubMed Central

    Dambreville, Charline; Labarre, Audrey; Thibaudier, Yann; Hurteau, Marie-France

    2015-01-01

    When speed changes during locomotion, both temporal and spatial parameters of the pattern must adjust. Moreover, at slow speeds the step-to-step pattern becomes increasingly variable. The objectives of the present study were to assess if the spinal locomotor network adjusts both temporal and spatial parameters from slow to moderate stepping speeds and to determine if it contributes to step-to-step variability in left-right symmetry observed at slow speeds. To determine the role of the spinal locomotor network, the spinal cord of 6 adult cats was transected (spinalized) at low thoracic levels and the cats were trained to recover hindlimb locomotion. Cats were implanted with electrodes to chronically record electromyography (EMG) in several hindlimb muscles. Experiments began once a stable hindlimb locomotor pattern emerged. During experiments, EMG and bilateral video recordings were made during treadmill locomotion from 0.1 to 0.4 m/s in 0.05 m/s increments. Cycle and stance durations significantly decreased with increasing speed, whereas swing duration remained unaffected. Extensor burst duration significantly decreased with increasing speed, whereas sartorius burst duration remained unchanged. Stride length, step length, and the relative distance of the paw at stance offset significantly increased with increasing speed, whereas the relative distance at stance onset and both the temporal and spatial phasing between hindlimbs were unaffected. Both temporal and spatial step-to-step left-right asymmetry decreased with increasing speed. Therefore, the spinal cord is capable of adjusting both temporal and spatial parameters during treadmill locomotion, and it is responsible, at least in part, for the step-to-step variability in left-right symmetry observed at slow speeds. PMID:26084910

  8. [Leukocytes as risk markers for cardiovascular disease in adolescents: association with birth characteristics, nutritional status and biochemical tests].

    PubMed

    do Prado Junior, Pedro Paulo; Faria, Franciane Rocha de; Faria, Eliane Rodrigues de; Franceschini, Sylvia do Carmo Castro; Priore, Silvia Eloiza

    2016-01-01

    To evaluate the correlation between the number of leukocytes and cardiovascular risks associated with birth characteristics, nutritional status and biochemical tests. Cross-sectional study developed with 475 adolescents, born between 1992 and 2001, in the municipality of Viçosa (MG). Maternal medical records were analyzed in the hospital units, and the following was recorded: birth weight and length, head circumference, chest circumference, Apgar score, gestational age. In adolescents, body mass index, skinfold thickness, body composition, blood count, biochemical tests and clinical variables were also assessed. The statistical analyses was carried out using Statistical Package for Social Sciences (SPSS) version 20.0 and Data Analysis and Statistical Software (STATA) with Kruskal-Wallis, Mann-Whitney, chi-square or Fisher's exact tests and Linear Regression. Significance level was set at α<0.05. The study was approved by the Research Ethics Committee of UFV for studies with human subjects. Weight and birth length, head and chest circumference were higher among boys. In adolescents, the number of leukocytes was higher in individuals with excess weight and body fat and high adiposity index, waist-to-height ratio and waist circumference. Only altered triglycerides showed differences between leukocyte medians. Regardless of the anthropometric variable of the final regression model, the stage of adolescence, number of platelets, eosinophils, monocytes and lymphocytes were associated with the increase in leukocytes. The birth variables were not associated with changes in leukocyte numbers, whereas the anthropometric variables were good indicators for a higher leukocyte count, regardless of the stage of adolescence and gender. Copyright © 2015 Sociedade de Pediatria de São Paulo. Publicado por Elsevier Editora Ltda. All rights reserved.

  9. The effect of high risk pregnancy on duration of neonatal stay in neonatal intensive care unit.

    PubMed

    Afrasiabi, Narges; Mohagheghi, Parisa; Kalani, Majid; Mohades, Gholam; Farahani, Zahra

    2014-08-01

    High risk pregnancies increase the risk of neonatal mortality and morbidity. In order to identify the influence of pregnancy complications on the period of neonatal stay in Neonatal Intensive Care Units (NICUs), an analysis has been carried out in our center. In a cross-sectional-descriptive analytical study, the data including NICU length of stay was gathered from 526 medical records of neonates. We also assessed their maternal complications such as premature rapture of membranes (PROM), urinary tract infection (UTI), preeclampsia, oligohydramnios, and twin/triplet pregnancy. Finally we analyzed the relation between variables by SPSS statistics software version 19. The level of significance was considered P<0.05. 37 of 526 neonatal medical records were excluded. Of the 489 babies hospitalized in NICU for 1 to 54 days; 28.42% born were preterm, 308 with birth weight <2500 gram and 170 with birth weight between 2500 and 4000 gram. There was a significant relation between length of neonatal NICU stay and maternal PROM (P=0.001), preeclampsia (P=0.01), UTI (P=0.02), multiple gestation (P=0.03), and oligohydramnios (P=0.003). We found a positive correlation between numbers of gestation and length of NICU stay (P=0.03). A positive correlation existed between neonatal complication and length of NICU stay (P<0.001). By increasing maternal health level and prenatal care services, neonatal outcome can be improved and length of stay in NICUs decreased.

  10. Determination of Normal Distribution of Distended Colon Volumes to Guide Performance of Colonic Imaging With Fluid Distention.

    PubMed

    Zheng, Karen S; Small, William C; Mittal, Pardeep K; Cai, Qingpo; Kang, Jian; Moreno, Courtney C

    2016-01-01

    The purpose was to determine the normal distribution of distended colon volumes as a guide for rectal contrast material administration protocols. All computed tomography colonography studies performed at Emory University Hospital, Atlanta, Georgia, between January 2009 and January 2015, were reviewed retrospectively. In total, 85 subjects were included in the analysis (64% [54 of 85] female and 36% [31 of 85] male). Mean patient age was 65 years (range: 42-86y). Distended colon volumes were determined from colon length and transaxial diameter measurements made using a 3-dimensional workstation. Age, sex, race, height, weight, and body mass index were recorded. The normal distributions of distended colon volumes and lengths were determined. Correlations between colonic volume and colonic length, and demographic variables were assessed. Mean colon volume was 2.1L (range: 0.7-4.4L). Nearly, 17% of patients had a distended colonic volume of >3L. Mean colon length was 197cm (range: 118-285cm). A weak negative correlation was found between age and colonic volume (r = -0.221; P = 0.04). A weak positive correlation was found between body mass index and colonic length (r = 0.368; P = 0.007). Otherwise, no significant correlations were found for distended colonic volume or length and demographic variables. In conclusion, an average of approximately 2L of contrast material may be necessary to achieve full colonic opacification. This volume is larger than previously reported volumes (0.8-1.5L) for rectal contrast material administration protocols. Copyright © 2015 Mosby, Inc. All rights reserved.

  11. Desert bird associations with broad-scale boundary length: Applications in avian conservation

    USGS Publications Warehouse

    Gutzwiller, K.J.; Barrow, W.C.

    2008-01-01

    1. Current understanding regarding the effects of boundaries on bird communities has originated largely from studies of forest-non-forest boundaries in mesic systems. To assess whether broad-scale boundary length can affect bird community structure in deserts, and to identify patterns and predictors of species' associations useful in avian conservation, we studied relations between birds and boundary-length variables in Chihuahuan Desert landscapes. Operationally, a boundary was the border between two adjoining land covers, and broad-scale boundary length was the total length of such borders in a large area. 2. Within 2-km radius areas, we measured six boundary-length variables. We analysed bird-boundary relations for 26 species, tested for assemblage-level patterns in species' associations with boundary-length variables, and assessed whether body size, dispersal ability and cowbird-host status were correlates of these associations. 3. The abundances or occurrences of a significant majority of species were associated with boundary-length variables, and similar numbers of species were related positively and negatively to boundary-length variables. 4. Disproportionately small numbers of species were correlated with total boundary length, land-cover boundary length and shrubland-grassland boundary length (variables responsible for large proportions of boundary length). Disproportionately large numbers of species were correlated with roadside boundary length and riparian vegetation-grassland boundary length (variables responsible for small proportions of boundary length). Roadside boundary length was associated (positively and negatively) with the most species. 5. Species' associations with boundary-length variables were not correlated with body size, dispersal ability or cowbird-host status. 6. Synthesis and applications. For the species we studied, conservationists can use the regressions we report as working models to anticipate influences of boundary-length changes on bird abundance and occurrence, and to assess avifaunal composition for areas under consideration for protection. Boundary-length variables associated with a disproportionate or large number of species can be used as foci for landscape management. Assessing the underlying causes of bird-boundary relations may improve the prediction accuracy of associated models. We therefore advocate local- and broad-scale manipulative experiments involving the boundary types with which species were correlated, as indicated by the regressions. ?? 2008 The Authors.

  12. Association between Self-Reported Participation in Decision Making and Inpatient Rehabilitation Outcomes.

    PubMed

    Wylegala, Juli A; Graham, James E; Karmarkar, Amol M; Illig, Caitlin; Illig, Sandra Bennett; Ottenbacher, Kenneth J

    2015-09-01

    Retrospective cross sectional. The purpose of this study was to assess the independent associations between perceived participation in clinical decision making on rehabilitation length of stay, discharge functional status, and discharge setting following inpatient rehabilitation. Active participation in the inpatient rehabilitation process, which is the most intense post-acute rehabilitation service, should lead to better patient experiences and outcomes. Self-reported information from participant interviews was linked with data in administrative medical records for Medicare beneficiaries discharged from inpatient rehabilitation facilities in 2007-2009. The decision making variable assessed participants' perceived participation in decision making during their inpatient rehabilitation stays. The three outcome variables were inpatient rehabilitation length of stay, discharge functional status, and discharge setting. Among the 41,110 participants interviewed, approximately 89% strongly agreed or agreed , and 12% disagreed that they participated in decision making during their rehabilitation stays. The multivariable regression models showed that greater participation in decision making was associated (p < .05) with slightly longer lengths of stay, higher discharge functional status, and increased likelihood of community discharge. Nearly nine in 10 Medicare beneficiaries report participating in decision making when receiving inpatient rehabilitation services. Increasing participation may lead to improvements in fundamental rehabilitation outcomes.

  13. 800,000 Years of Arctic Climate Variability: Insights from Lake El'gygytgyn, Far East Russia

    NASA Astrophysics Data System (ADS)

    Castañeda, I. S.; Habicht, H.; Patterson, M. O.; Burns, S. J.; Deconto, R. M.; Brigham-Grette, J.

    2017-12-01

    The regional response of the high Arctic to past climate variability is little known prior to 100,000 years ago. In 2009, a 3.6 Ma sediment core was recovered from Lake El'gygytgyn (Russia), the largest and oldest unglaciated Arctic lake basin. These sediments offer a unique opportunity to examine Plio-Pleistocene high-latitude continental climate variability. Determining the magnitude of past Arctic temperature and precipitation variability is especially relevant to understanding the mechanisms and feedbacks contributing to arctic amplification. Here we present results of ongoing organic geochemical analyses of Lake El'gygytgyn sediments focusing on the past 800,000 years. We use the methylation and cyclization index of branched tetraethers (MBT'/CBT) to reconstruct past temperature (Weijers et al., 2007; Peterse et al., 2012; De Jonge et al., 2014) and ratios of plant leaf waxes to examine vegetation variability within the lake catchment. In addition, algal biomarkers and bulk carbon isotopes provide insights into past changes in primary productivity. Trends noted in the MBT'/CBT record are in close agreement with pollen-based temperature estimates throughout the entire core and reveal a strong response to interglacial-glacial variability as well as local summer insolation. Our temperature reconstructions indicate the terrestrial Arctic experienced both warm interglacials and mild glacial periods during the Mid-Pleistocene but transitioned to more extreme temperature fluctuations in the more recent part of the record. Plant leaf wax average chain lengths suggest that glacial intervals were marked by increased aridity, while interglacial periods were wetter at Lake El'gygytgyn. Time-series analysis of the organic geochemical temperature and vegetation reconstructions records revealed variability at precession and obliquity frequencies, respectively. We also find a signal of the Mid-Brunhes Event (MBE) recorded in numerous Lake El'gygytgyn proxy records. Pre- and post-MBE differences are likely attributed to shifts in atmospheric circulation due to the stratification and warming in the North Pacific associated with changes in AABW production, thus providing further support for teleconnections between the high northern and southern latitudes.

  14. Variable-Length Computerized Adaptive Testing: Adaptation of the A-Stratified Strategy in Item Selection with Content Balancing

    ERIC Educational Resources Information Center

    Huo, Yan

    2009-01-01

    Variable-length computerized adaptive testing (CAT) can provide examinees with tailored test lengths. With the fixed standard error of measurement ("SEM") termination rule, variable-length CAT can achieve predetermined measurement precision by using relatively shorter tests compared to fixed-length CAT. To explore the application of…

  15. Re-assessing the role of plant community change and climate in the PETM n-alkane record

    NASA Astrophysics Data System (ADS)

    Bush, R. T.; Baczynski, A. A.; McInerney, F. A.; Chen, D.

    2012-12-01

    The terrestrial leaf wax n-alkane record of the Paleocene-Eocene Thermal Maximum (PETM) in the Bighorn Basin, Wyoming, shows large excursions in both carbon isotope (δ13C) values and n-alkane average chain length (ACL). At the onset of the PETM, ACL values increase from ~28.5 to ~30.1 while the negative carbon isotope excursion (CIE) is 4-6‰ in magnitude and larger than δ13C records from other materials. It has been hypothesized previously that both the ACL excursion and the large magnitude of the CIE were caused by a concurrent turnover in the local flora from a mixed conifer/angiosperm community before the PETM to a different suite of angiosperm species during the PETM. Here, we present the results of a meta-analysis of data (>2000 data from 89 sources, both published and unpublished) on n-alkane amounts and chain length distributions in modern plants from around the world. We applied the data in two sets of comparisons: 1) within and among plant groups such as herbs and graminoids, and 2) between plants and climate, using reported collection locations for outdoor plants and climate values generated via GIS extraction of WorldClim modeled data. We show that angiosperms, as group, produce more n-alkanes than do gymnosperms by 1-2 orders of magnitude, and this means that the gymnosperm contribution to a mixed soil n-alkane pool would be negligible, even in an ecosystem where gymnosperms dominated (i.e. the pre/post-PETM ecosystems). The modern plant data also demonstrate that turnover of the plant community during the PETM, even among only the angiosperm species, is likely not the source of the observed ACL excursion. First, we constructed "representative" groups of PETM and pre/post-PETM communities using living relative species at the Chicago Botanic Garden and find no significant difference in chain length distributions between the two groups. Second and moreover, the modern plant data reveal that n-alkane chain length distributions are tremendously variable within large vascular plant groups--both functional groups such as woody plants or graminoids as well as phylogenetic groups at the family level or higher. This variability makes it difficult at best to use n-alkane chain lengths to distinguish one vascular group from another, as was previously suggested. Instead, our results suggest that chain length distributions and ACL are driven more by climate, especially temperature. Longer chain lengths, with their increased hydrophobicity, would likely experience favorable selection under warmer or drier conditions where leaf water loss is likely to be a greater stress. Thus, it may be that we can interpret the increase in ACL during the PETM as a direct response by the flora to increased temperature during the hyperthermal event, and n-alkane chain length distributions, properly constrained, may possibly serve as a qualitative paleotemperature proxy.

  16. Reading sentences of uniform word length: Evidence for the adaptation of the preferred saccade length during reading.

    PubMed

    Cutter, Michael G; Drieghe, Denis; Liversedge, Simon P

    2017-11-01

    In the current study, the effect of removing word length variability within sentences on spatial aspects of eye movements during reading was investigated. Participants read sentences that were uniform in terms of word length, with each sentence consisting entirely of three-, four-, or five-letter words, or a combination of these word lengths. Several interesting findings emerged. Adaptation of the preferred saccade length occurred for sentences with different uniform word length; participants would be more accurate at making short saccades while reading uniform sentences of three-letter words, while they would be more accurate at making long saccades while reading uniform sentences of five-letter words. Furthermore, word skipping was affected such that three- and four-letter words were more likely, and five-letter words less likely, to be directly fixated in uniform compared to non-uniform sentences. It is argued that saccadic targeting during reading is highly adaptable and flexible toward the characteristics of the text currently being read, as opposed to the idea implemented in most current models of eye movement control during reading that readers develop a preference for making saccades of a certain length across a lifetime of experience with a given language. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  17. A global multiproxy database for temperature reconstructions of the Common Era.

    PubMed

    2017-07-11

    Reproducible climate reconstructions of the Common Era (1 CE to present) are key to placing industrial-era warming into the context of natural climatic variability. Here we present a community-sourced database of temperature-sensitive proxy records from the PAGES2k initiative. The database gathers 692 records from 648 locations, including all continental regions and major ocean basins. The records are from trees, ice, sediment, corals, speleothems, documentary evidence, and other archives. They range in length from 50 to 2000 years, with a median of 547 years, while temporal resolution ranges from biweekly to centennial. Nearly half of the proxy time series are significantly correlated with HadCRUT4.2 surface temperature over the period 1850-2014. Global temperature composites show a remarkable degree of coherence between high- and low-resolution archives, with broadly similar patterns across archive types, terrestrial versus marine locations, and screening criteria. The database is suited to investigations of global and regional temperature variability over the Common Era, and is shared in the Linked Paleo Data (LiPD) format, including serializations in Matlab, R and Python.

  18. A global multiproxy database for temperature reconstructions of the Common Era

    USGS Publications Warehouse

    Emile-Geay, Julian; McKay, Nicholas P.; Kaufman, Darrell S.; von Gunten, Lucien; Wang, Jianghao; Anchukaitis, Kevin J.; Abram, Nerilie J.; Addison, Jason A.; Curran, Mark A.J.; Evans, Michael N.; Henley, Benjamin J.; Hao, Zhixin; Martrat, Belen; McGregor, Helen V.; Neukom, Raphael; Pederson, Gregory T.; Stenni, Barbara; Thirumalai, Kaustubh; Werner, Johannes P.; Xu, Chenxi; Divine, Dmitry V.; Dixon, Bronwyn C.; Gergis, Joelle; Mundo, Ignacio A.; Nakatsuka, T.; Phipps, Steven J.; Routson, Cody C.; Steig, Eric J.; Tierney, Jessica E.; Tyler, Jonathan J.; Allen, Kathryn J.; Bertler, Nancy A. N.; Bjorklund, Jesper; Chase, Brian M.; Chen, Min-Te; Cook, Ed; de Jong, Rixt; DeLong, Kristine L.; Dixon, Daniel A.; Ekaykin, Alexey A.; Ersek, Vasile; Filipsson, Helena L.; Francus, Pierre; Freund, Mandy B.; Frezzotti, M.; Gaire, Narayan P.; Gajewski, Konrad; Ge, Quansheng; Goosse, Hugues; Gornostaeva, Anastasia; Grosjean, Martin; Horiuchi, Kazuho; Hormes, Anne; Husum, Katrine; Isaksson, Elisabeth; Kandasamy, Selvaraj; Kawamura, Kenji; Koc, Nalan; Leduc, Guillaume; Linderholm, Hans W.; Lorrey, Andrew M.; Mikhalenko, Vladimir; Mortyn, P. Graham; Motoyama, Hideaki; Moy, Andrew D.; Mulvaney, Robert; Munz, Philipp M.; Nash, David J.; Oerter, Hans; Opel, Thomas; Orsi, Anais J.; Ovchinnikov, Dmitriy V.; Porter, Trevor J.; Roop, Heidi; Saenger, Casey; Sano, Masaki; Sauchyn, David; Saunders, K.M.; Seidenkrantz, Marit-Solveig; Severi, Mirko; Shao, X.; Sicre, Marie-Alexandrine; Sigl, Michael; Sinclair, Kate; St. George, Scott; St. Jacques, Jeannine-Marie; Thamban, Meloth; Thapa, Udya Kuwar; Thomas, E.; Turney, Chris; Uemura, Ryu; Viau, A.E.; Vladimirova, Diana O.; Wahl, Eugene; White, James W. C.; Yu, Z.; Zinke, Jens

    2017-01-01

    Reproducible climate reconstructions of the Common Era (1 CE to present) are key to placing industrial-era warming into the context of natural climatic variability. Here we present a community-sourced database of temperature-sensitive proxy records from the PAGES2k initiative. The database gathers 692 records from 648 locations, including all continental regions and major ocean basins. The records are from trees, ice, sediment, corals, speleothems, documentary evidence, and other archives. They range in length from 50 to 2000 years, with a median of 547 years, while temporal resolution ranges from biweekly to centennial. Nearly half of the proxy time series are significantly correlated with HadCRUT4.2 surface temperature over the period 1850–2014. Global temperature composites show a remarkable degree of coherence between high- and low-resolution archives, with broadly similar patterns across archive types, terrestrial versus marine locations, and screening criteria. The database is suited to investigations of global and regional temperature variability over the Common Era, and is shared in the Linked Paleo Data (LiPD) format, including serializations in Matlab, R and Python.

  19. Heart rate variability is associated with social value orientation in males but not females.

    PubMed

    Lischke, Alexander; Mau-Moeller, Anett; Jacksteit, Robert; Pahnke, Rike; Hamm, Alfons O; Weippert, Matthias

    2018-05-09

    Phylogenetic and neurobiological theories suggest that inter-individual differences in high frequency heart rate variability (HF-HRV) are associated with inter-individual differences in social behavior and social cognition. To test these theories, we investigated whether individuals with high and low HF-HRV would show different preferences for cooperative behavior in social contexts. We recorded resting state HF-HRV in 84 healthy individuals before they completed the Social Value Orientation task, a well-established measure of cooperative preferences. HF-HRV was derived from short-term (300 s) and ultra-short-term (60 s, 120 s) recordings of participants' heart rate to determine the robustness of possible findings. Irrespective of recording length, we found a sex-dependent association between inter-individual differences in HF-HRV and inter-individual differences in social value orientation: The preference for cooperation was more pronounced among individuals with high as compared low HF-HRV, albeit only in male and not in female participants. These findings suggest that males with high HF-HRV are more inclined to engage in cooperative behavior than males with low HF-HRV.

  20. A global multiproxy database for temperature reconstructions of the Common Era

    PubMed Central

    Emile-Geay, Julien; McKay, Nicholas P.; Kaufman, Darrell S.; von Gunten, Lucien; Wang, Jianghao; Anchukaitis, Kevin J.; Abram, Nerilie J.; Addison, Jason A.; Curran, Mark A.J.; Evans, Michael N.; Henley, Benjamin J.; Hao, Zhixin; Martrat, Belen; McGregor, Helen V.; Neukom, Raphael; Pederson, Gregory T.; Stenni, Barbara; Thirumalai, Kaustubh; Werner, Johannes P.; Xu, Chenxi; Divine, Dmitry V.; Dixon, Bronwyn C.; Gergis, Joelle; Mundo, Ignacio A.; Nakatsuka, Takeshi; Phipps, Steven J.; Routson, Cody C.; Steig, Eric J.; Tierney, Jessica E.; Tyler, Jonathan J.; Allen, Kathryn J.; Bertler, Nancy A.N.; Björklund, Jesper; Chase, Brian M.; Chen, Min-Te; Cook, Ed; de Jong, Rixt; DeLong, Kristine L.; Dixon, Daniel A.; Ekaykin, Alexey A.; Ersek, Vasile; Filipsson, Helena L.; Francus, Pierre; Freund, Mandy B.; Frezzotti, Massimo; Gaire, Narayan P.; Gajewski, Konrad; Ge, Quansheng; Goosse, Hugues; Gornostaeva, Anastasia; Grosjean, Martin; Horiuchi, Kazuho; Hormes, Anne; Husum, Katrine; Isaksson, Elisabeth; Kandasamy, Selvaraj; Kawamura, Kenji; Kilbourne, K. Halimeda; Koç, Nalan; Leduc, Guillaume; Linderholm, Hans W.; Lorrey, Andrew M.; Mikhalenko, Vladimir; Mortyn, P. Graham; Motoyama, Hideaki; Moy, Andrew D.; Mulvaney, Robert; Munz, Philipp M.; Nash, David J.; Oerter, Hans; Opel, Thomas; Orsi, Anais J.; Ovchinnikov, Dmitriy V.; Porter, Trevor J.; Roop, Heidi A.; Saenger, Casey; Sano, Masaki; Sauchyn, David; Saunders, Krystyna M.; Seidenkrantz, Marit-Solveig; Severi, Mirko; Shao, Xuemei; Sicre, Marie-Alexandrine; Sigl, Michael; Sinclair, Kate; St. George, Scott; St. Jacques, Jeannine-Marie; Thamban, Meloth; Kuwar Thapa, Udya; Thomas, Elizabeth R.; Turney, Chris; Uemura, Ryu; Viau, Andre E.; Vladimirova, Diana O.; Wahl, Eugene R.; White, James W.C.; Yu, Zicheng; Zinke, Jens

    2017-01-01

    Reproducible climate reconstructions of the Common Era (1 CE to present) are key to placing industrial-era warming into the context of natural climatic variability. Here we present a community-sourced database of temperature-sensitive proxy records from the PAGES2k initiative. The database gathers 692 records from 648 locations, including all continental regions and major ocean basins. The records are from trees, ice, sediment, corals, speleothems, documentary evidence, and other archives. They range in length from 50 to 2000 years, with a median of 547 years, while temporal resolution ranges from biweekly to centennial. Nearly half of the proxy time series are significantly correlated with HadCRUT4.2 surface temperature over the period 1850–2014. Global temperature composites show a remarkable degree of coherence between high- and low-resolution archives, with broadly similar patterns across archive types, terrestrial versus marine locations, and screening criteria. The database is suited to investigations of global and regional temperature variability over the Common Era, and is shared in the Linked Paleo Data (LiPD) format, including serializations in Matlab, R and Python. PMID:28696409

  1. Reading strategies in Spanish developmental dyslexics.

    PubMed

    Suárez-Coalla, Paz; Cuetos, Fernando

    2012-07-01

    Cross-linguistic studies suggest that the orthographic system determines the reading performance of dyslexic children. In opaque orthographies, the fundamental feature of developmental dyslexia is difficulty in reading accuracy, whereas slower reading speed is more common in transparent orthographies. The aim of the current study was to examine the extent to which different variables of words affect reaction times and articulation times in developmental dyslexics. A group of 19 developmental dyslexics of different ages and an age-matched group of 19 children without reading disabilities completed a word naming task. The children were asked to read 100 nouns that differed in length, frequency, age of acquisition, imageability, and orthographic neighborhood. The stimuli were presented on a laptop computer, and the responses were recorded using DMDX software. We conducted analyses of mixed-effects models to determine which variables influenced reading times in dyslexic children. We found that word naming skills in dyslexic children are affected predominantly by length, while in non-dyslexics children the principal variable is the age of acquisition, a lexical variable. These findings suggest that Spanish-speaking developmental dyslexics use a sublexical procedure for reading words, which is reflected in slower speed when reading long words. In contrast, normal children use a lexical strategy, which is frequently observed in readers of opaque languages.

  2. Models for forecasting the flowering of Cornicabra olive groves.

    PubMed

    Rojo, Jesús; Pérez-Badia, Rosa

    2015-11-01

    This study examined the impact of weather-related variables on flowering phenology in the Cornicabra olive tree and constructed models based on linear and Poisson regression to forecast the onset and length of the pre-flowering and flowering phenophases. Spain is the world's leading olive oil producer, and the Cornicabra variety is the second largest Spanish variety in terms of surface area. However, there has been little phenological research into this variety. Phenological observations were made over a 5-year period (2009-2013) at four sampling sites in the province of Toledo (central Spain). Results showed that the onset of the pre-flowering phase is governed largely by temperature, which displayed a positive correlation with the temperature in the start of dormancy (November) and a negative correlation during the months prior to budburst (January, February and March). A similar relationship was recorded for the onset of flowering. Other weather-related variables, including solar radiation and rainfall, also influenced the succession of olive flowering phenophases. Linear models proved the most suitable for forecasting the onset and length of the pre-flowering period and the onset of flowering. The onset and length of pre-flowering can be predicted up to 1 or 2 months prior to budburst, whilst the onset of flowering can be forecast up to 3 months beforehand. By contrast, a nonlinear model using Poisson regression was best suited to predict the length of the flowering period.

  3. Variability in energy cost and walking gait during race walking in competitive race walkers.

    PubMed

    Brisswalter, J; Fougeron, B; Legros, P

    1998-09-01

    The aim of this study was to examine the variability of energy cost (Cw) and race walking gait after a 3-h walk at the competition pace in race walkers of the same performance level. Nine competitive race walkers were studied. In the same week, after a first test of VO2max determination, each subject completed two submaximal treadmill walks (6 min length, 0% grade, 12 km X h(-1) speed) before and after a 3-h overground test completed at the individual competition speed of the race walker. During the two submaximal tests, subjects were filmed between the 2nd and the 4th min, and physiological parameters were recorded between the 4th and the 6th min. Results showed two trends. On the one hand, we observed a significant and systematic increase in energy cost of walking (mean deltaCw = 8.4%), whereas no variation in the gait kinematics prescribed by the rules of race walking was recorded. On the other hand, this increase in metabolic energy demand was accompanied by variations of different magnitude and direction of stride length, of the excursion of the heel and of the maximal ankle flexion at toe-off among the race walkers. These results indicated that competitive race walkers are able to maintain their walking gait with exercise duration apart from a systematic increase in energy cost. Moreover, in this form of locomotion the effect of fatigue on the gait variability seems to be an individual function of the race walk constraints and the constraints of the performer.

  4. Determination of baseline periods of record for selected streamflow-gaging stations in and near Oklahoma for use in modeling applications

    USGS Publications Warehouse

    Esralew, Rachel A.

    2010-01-01

    Use of historical streamflow data from a least-altered period of record can be used in calibration of various modeling applications that are used to characterize least-altered flow and predict the effects of proposed streamflow alteration. This information can be used to enhance water-resources planning. A baseline period of record was determined for selected streamflow-gaging stations that can be used as a calibration dataset for modeling applications. The baseline period of record was defined as a period that is least-altered by anthropogenic activity and has sufficient streamflow record length to represent extreme climate variability. Streamflow data from 171 stations in and near Oklahoma with a minimum of 10 complete water years of daily streamflow record through water year 2007 and drainage areas that were less than 2,500 square miles were considered for use in the baseline period analysis. The first step to determine the least-altered period of record was to evaluate station information by using previous publications, historical station record notes, and information gathered from oral and written communication with hydrographers familiar with selected stations. The second step was to indentify stations that had substantial effects from upstream regulation by evaluating the location and extent of dams in the drainage basin. The third step was (a) the analysis of annual hydrographs and included visual hydrograph analysis for selected stations with 20 or more years of streamflow record, (b) analysis of covariance of double-mass curves, and (c) Kendall's tau trend analysis to detect statistically significant trends in base flow, runoff, total flow, and base-flow index related to anthropogenic activity for selected stations with 15 or more years of streamflow record. A preliminary least-altered period of record for each stream was identified by removing the period of streamflow record when streams were substantially affected by anthropogenic activity. After streamflow record was removed from designation as a least-altered period, stations that did not have at least 10 years of remaining continuous streamflow record were considered to have an insufficient baseline period for modeling applications. An optimum minimum period of record was determined for each of the least-altered periods for each station to ensure a sufficient streamflow record length to provide a representative sample of annual climate variability. An optimum minimum period of 10 years or more was evaluated by analyzing the variability of annual precipitation for selected 5-, 10-, 15-, 25-, and 35-year periods for each of 20 climate divisions that contained stations used in the baseline period analysis. The distribution of annual precipitation was compared for each consecutive overlapping 5-year period to the period 1925-2007 by using a Wilcoxon rank-sum test. The least-altered period of record for stations was also compared to the period 1925-2007 by using a Wilcoxon rank-sum test. The results of this analysis were used to determine how many years of annual precipitation data were needed for the selected period to be statistically similar to the distribution of annual precipitation data for a long-term period, 1925-2007. Minimum optimum periods ranged from 10 to 35 years and varied by climate division. A final baseline period was determined for 111 stations that had a baseline period of at least 10 years of continuous streamflow record after the record-elimination process. A suitable baseline period of record for use in modeling applications could not be identified for 58 of the initial 171 stations because of substantial anthropogenic alteration of the stream or drainage basin and for 2 stations because the least-altered period of record was not representative of annual climate variability. The baseline period for each station was rated ?excellent?, ?good?, ?fair?, ?poor?, or ?no baseline period.? This rating was based on a qualitative evaluation of t

  5. [Triage duration times: a prospective descriptive study in a level 1° emergency department].

    PubMed

    Bambi, Stefano; Ruggeri, Marco

    2017-01-01

    Triage is the most important tool for clinical risk management in emergency departments (ED). The timing measurement of its phases is fundamental to establish indicators and standards for the optimization of the system. To evaluate the duration time of the phases of triage; to evaluate some variables exerting influence on nurses' performance. prospective descriptive study performed in the ED of Careggi Teaching Hospital in Florence. 14 nurses enrolled by stratified randomization proportion (1/3 of the whole staff ), according to classes of length of service. Triage processes on 150 adult patients were recorded. The mean age of nurses was 39.7 years (SD ± 5.2, range 29-50); the average length of service was 10.3 years (SD ± 4.4, range 3-18); average of triage experience was 8.6 years (SD ± 4.3, range 2-13). The median time from patient's arrival to the end of the triage process was 04': 04" (range 00':47"- 18':08"); the median duration of triage was 01':11" (range 00':07" -11':27"). The length of service and triage experience did not influence the medians of recorded intervals of time, but there were some limitations due to the low sample size. Interruptions were observed 111 (74%) of triage cases. the recorded triage time intervals were similar to those reported in international literature. Actions are needed to reduce the impact of interruptions on triage process' times.

  6. Association of functional genetic variants of A-kinase anchoring protein 10 with QT interval length in full-term Polish newborns.

    PubMed

    Łoniewska, Beata; Kaczmarczyk, Mariusz; Clark, Jeremy Simon; Gorący, Iwona; Horodnicka-Józwa, Anita; Ciechanowicz, Andrzej

    2015-03-16

    A-Kinase Anchoring Proteins (AKAPs) coordinate the specificity of protein kinase A signaling by localizing the kinase to subcellular sites. The 1936G (V646) AKAP10 allele has been associated in adults with low cholinergic/vagus nerve sensitivity, shortened PR intervals in ECG recording and in newborns with increased blood pressure and higher cholesterol cord blood concentration. The aim of the study was to answer the question of whether 1936A > G AKAP10 polymorphism is associated with the newborn electrocardiographic variables. Electrocardiograms were recorded from 114 consecutive healthy Polish newborns (55 females, 59 males), born after 37 gestational weeks to healthy women with uncomplicated pregnancies. All recordings were made between 3(rd) and 7(th) day of life to avoid QT variability. The heart rate per minute and duration of PR, QRS, RR and QT intervals were usually measured. The ECGs were evaluated independently by three observers. At birth, cord blood of neonates was obtained for isolation of genomic DNA. The distribution of anthropometric and electrocardiographic variables in our cohort approached normality (skewness < 2 for all variables). No significant differences in anthropometric variables and electrocardiographic traits with respect to AKAP10 genotype were found. Multiple regression analysis with adjustment for gender, gestational age and birth mass revealed that QTc interval in GG AKAP10 homozygotes was significantly longer, but in range, when compared with A alleles carriers (AA + AG, recessive mode of inheritance). No rhythm disturbances were observed. Results demonstrate possible association between AKAP10 1936A > G variant and QTc interval in Polish newborns.

  7. Cerebral oximetry during cardiac surgery: the association between cerebral oxygen saturation and perioperative patient variables.

    PubMed

    Apostolidou, Ioanna; Morrissette, Greg; Sarwar, Muhammad F; Konia, Mojca R; Kshettry, Vibhu R; Wahr, Joyce A; Lobbestael, Aaron A; Nussmeier, Nancy A

    2012-12-01

    This "real-world" study was designed to assess the patterns of regional cerebral oxygen saturation (rSO(2)) change during adult cardiac surgery. A secondary objective was to determine any relation between perioperative rSO(2) (baseline and during surgery) and patient characteristics or intraoperative variables. Prospective, observational, multicenter, nonrandomized clinical study. Cardiac operating rooms at 3 academic medical centers. Ninety consecutive adult patients presenting for cardiac surgery with or without cardiopulmonary bypass. Patients received standard care at each institution plus bilateral forehead recordings of cerebral oxygen saturation with the 7600 Regional Oximeter System (Nonin Medical, Plymouth, MN). The average baseline (before induction) rSO(2) was 63.9 ± 8.8% (range 41%-95%); preoperative hematocrit correlated with baseline rSO(2) (0.48% increase for each 1% increase in hematocrit, p = 0.008). The average nadir (lowest recorded rSO(2) for any given patient) was 54.9 ± 6.6% and was correlated with on-pump surgery, baseline rSO(2), and height. Baseline rSO(2) was found to be an independent predictor of length of stay (hazard ratio 1.044, confidence interval 1.02-1.07, for each percentage of baseline rSO(2)). In cardiac surgical patients, lower baseline rSO(2) value, on-pump surgery, and height were significant predictors of nadir rSO(2), whereas only baseline rSO(2) was a predictor of postoperative length of stay. These findings support previous research on the predictive value of baseline rSO(2) on length of stay and emphasize the need for further research regarding the clinical relevance of baseline rSO(2) and intraoperative changes. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. Intraradicular Appearances Affect Radiographic Interpretation of the Periapical Area.

    PubMed

    Biscontine, Ana C; Diliberto, Adam J; Hatton, John F; Woodmansey, Karl F

    2017-12-01

    No research exists evaluating the influences of specific variables such as obturation length, radiodensity, or the presence of voids on interpretation of periradicular area. The purpose of this study was to evaluate the effects of obturation length, radiodensity, and the presence of voids on the radiographic interpretations of periapical areas. In a Web-based survey, 3 test image groups of variable obturation lengths, radiodensities, and numbers of voids were presented to observers for evaluation of the periapical areas. Intracanal areas of the images were altered by using Adobe Photoshop to create 3 test image groups. Each observer reviewed 2 control images and 1 image from each test image group. Responses were recorded in a 5-point Likert-type scale. Within each test image group, the periapical areas were identical. Kruskal-Wallis, Mann-Whitney U, and Cliff's delta statistical tests were used to analyze results. A total of 748 observer responses were analyzed. Significant differences (P ≤ .01) in the median Likert-type scale responses were identified between the following paired groups: 3 mm short and 1 mm short, 3 mm short and flush, lower radiodensity and higher radiodensity, lower radiodensity and intermediate radiodensity, no voids and several voids, and several voids and single void. Effect sizes ranged from 0.19 to 0.41. Significant differences were noted within all 3 test image groups: length, radiodensity, and presence of voids. Length of obturation had the largest effect on interpretation of the periapical area, with the 3 mm short radiographic obturation length image interpreted less favorably. Copyright © 2017 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  9. Genotypic variability for root/shoot parameters under water stress in some advanced lines of cotton (Gossypium hirsutum L.).

    PubMed

    Riaz, M; Farooq, J; Sakhawat, G; Mahmood, A; Sadiq, M A; Yaseen, M

    2013-02-27

    Research pertaining to genetic variability parameters, heritability, and genotypic, phenotypic, simple, and environmental correlations for various seedling traits in five elite advanced cotton (Gossypium hirsutum L.) lines (FH-113, FH-114, FH-941, FH-942, and FH-2015) and one check (CIM-496) was carried out during October and November 2010 under greenhouse conditions at the Cotton Research Institute (Faisalabad, Pakistan). Material was raised in plastic tubes with a randomized complete block design replicated three times. Three drought shocks were applied by withholding water from the tube-sown plants for 8-, 10-, and 12-day intervals. After 60 days of sowing, data on root/shoot traits like root length (cm), shoot length (cm), root weight (g), shoot fresh weight (g), lateral root number, root dry weight (g) shoot dry weight (g), and total plant weight (g) were recorded. Considerable genotypic variations existed between genotypes for all seedling characters. Higher broad-sense heritability estimates were found for all traits studied. Maximum broad-sense heritability coupled with high genetic advance in root length (0.99, 17.34), lateral root number (0.91, 2.89), and shoot length (0.90, 4.35) suggested a potential for genetic improvement through breeding and selection. The correlation coefficients among root length, shoot length, root dry weight, fresh shoot weight, and total plant weight were positively and significantly correlated; thus, they can be selected simultaneously as drought tolerance selection indexes owing to the absence of undesired relationships. Genotypes FH-942 and FH-113 had the lowest excised leaf water loss during the first 4 h and also for the next 4 h. Therefore, these two advanced lines (FH-942 and FH-113) with high initial water content and lower excised leaf water loss had better adaptation to water stress.

  10. Variability of Anticipatory Postural Adjustments During Gait Initiation in Individuals With Parkinson Disease.

    PubMed

    Lin, Cheng-Chieh; Creath, Robert A; Rogers, Mark W

    2016-01-01

    In people with Parkinson disease (PD), difficulties with initiating stepping may be related to impairments of anticipatory postural adjustments (APAs). Increased variability in step length and step time has been observed in gait initiation in individuals with PD. In this study, we investigated whether the ability to generate consistent APAs during gait initiation is compromised in these individuals. Fifteen subjects with PD and 8 healthy control subjects were instructed to take rapid forward steps after a verbal cue. The changes in vertical force and ankle marker position were recorded via force platforms and a 3-dimensional motion capture system, respectively. Means, standard deviations, and coefficients of variation of both timing and magnitude of vertical force, as well as stepping variables, were calculated. During the postural phase of gait initiation the interval was longer and the force modulation was smaller in subjects with PD. Both the variability of timing and force modulation were larger in subjects with PD. Individuals with PD also had a longer time to complete the first step, but no significant differences were found for the variability of step time, length, and speed between groups. The increased variability of APAs during gait initiation in subjects with PD could affect posture-locomotion coupling, and lead to start hesitation, and even falls. Future studies are needed to investigate the effect of rehabilitation interventions on the variability of APAs during gait initiation in individuals with PD.Video abstract available for more insights from the authors (see Supplemental Digital Content 1, http://links.lww.com/JNPT/A119).

  11. Late Quaternary glacier sensitivity to temperature and precipitation distribution in the Southern Alps of New Zealand

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ann V. Rowan; Simon H. Brocklehurst; David M. Schultz

    2014-05-01

    Glaciers respond to climate variations and leave geomorphic evidence that represents an important terrestrial paleoclimate record. However, the accuracy of paleoclimate reconstructions from glacial geology is limited by the challenge of representing mountain meteorology in numerical models. Precipitation is usually treated in a simple manner and yet represents difficult-to-characterize variables such as amount, distribution, and phase. Furthermore, precipitation distributions during a glacial probably differed from present-day interglacial patterns. We applied two models to investigate glacier sensitivity to temperature and precipitation in the eastern Southern Alps of New Zealand. A 2-D model was used to quantify variations in the length ofmore » the reconstructed glaciers resulting from plausible precipitation distributions compared to variations in length resulting from change in mean annual air temperature and precipitation amount. A 1-D model was used to quantify variations in length resulting from interannual climate variability. Assuming that present-day interglacial values represent precipitation distributions during the last glacial, a range of plausible present-day precipitation distributions resulted in uncertainty in the Last Glacial Maximum length of the Pukaki Glacier of 17.1?km (24%) and the Rakaia Glacier of 9.3?km (25%), corresponding to a 0.5°C difference in temperature. Smaller changes in glacier length resulted from a 50% decrease in precipitation amount from present-day values (-14% and -18%) and from a 50% increase in precipitation amount (5% and 9%). Our results demonstrate that precipitation distribution can produce considerable variation in simulated glacier extents and that reconstructions of paleoglaciers should include this uncertainty.« less

  12. Verification of relationships between anthropometric variables among ureteral stents recipients and ureteric lengths: a challenge for Vitruvian-da Vinci theory.

    PubMed

    Acelam, Philip A

    2015-01-01

    To determine and verify how anthropometric variables correlate to ureteric lengths and how well statistical models approximate the actual ureteric lengths. In this work, 129 charts of endourological patients (71 females and 58 males) were studied retrospectively. Data were gathered from various research centers from North and South America. Continuous data were studied using descriptive statistics. Anthropometric variables (age, body surface area, body weight, obesity, and stature) were utilized as predictors of ureteric lengths. Linear regressions and correlations were used for studying relationships between the predictors and the outcome variables (ureteric lengths); P-value was set at 0.05. To assess how well statistical models were capable of predicting the actual ureteric lengths, percentages (or ratios of matched to mismatched results) were employed. The results of the study show that anthropometric variables do not correlate well to ureteric lengths. Statistical models can partially estimate ureteric lengths. Out of the five anthropometric variables studied, three of them: body frame, stature, and weight, each with a P<0.0001, were significant. Two of the variables: age (R (2)=0.01; P=0.20) and obesity (R (2)=0.03; P=0.06), were found to be poor estimators of ureteric lengths. None of the predictors reached the expected (match:above:below) ratio of 1:0:0 to qualify as reliable predictors of ureteric lengths. There is not sufficient evidence to conclude that anthropometric variables can reliably predict ureteric lengths. These variables appear to lack adequate specificity as they failed to reach the expected (match:above:below) ratio of 1:0:0. Consequently, selections of ureteral stents continue to remain a challenge. However, height (R (2)=0.68) with the (match:above:below) ratio of 3:3:4 appears suited for use as estimator, but on the basis of decision rule. Additional research is recommended for stent improvements and ureteric length determinations.

  13. Verification of relationships between anthropometric variables among ureteral stents recipients and ureteric lengths: a challenge for Vitruvian-da Vinci theory

    PubMed Central

    Acelam, Philip A

    2015-01-01

    Objective To determine and verify how anthropometric variables correlate to ureteric lengths and how well statistical models approximate the actual ureteric lengths. Materials and methods In this work, 129 charts of endourological patients (71 females and 58 males) were studied retrospectively. Data were gathered from various research centers from North and South America. Continuous data were studied using descriptive statistics. Anthropometric variables (age, body surface area, body weight, obesity, and stature) were utilized as predictors of ureteric lengths. Linear regressions and correlations were used for studying relationships between the predictors and the outcome variables (ureteric lengths); P-value was set at 0.05. To assess how well statistical models were capable of predicting the actual ureteric lengths, percentages (or ratios of matched to mismatched results) were employed. Results The results of the study show that anthropometric variables do not correlate well to ureteric lengths. Statistical models can partially estimate ureteric lengths. Out of the five anthropometric variables studied, three of them: body frame, stature, and weight, each with a P<0.0001, were significant. Two of the variables: age (R2=0.01; P=0.20) and obesity (R2=0.03; P=0.06), were found to be poor estimators of ureteric lengths. None of the predictors reached the expected (match:above:below) ratio of 1:0:0 to qualify as reliable predictors of ureteric lengths. Conclusion There is not sufficient evidence to conclude that anthropometric variables can reliably predict ureteric lengths. These variables appear to lack adequate specificity as they failed to reach the expected (match:above:below) ratio of 1:0:0. Consequently, selections of ureteral stents continue to remain a challenge. However, height (R2=0.68) with the (match:above:below) ratio of 3:3:4 appears suited for use as estimator, but on the basis of decision rule. Additional research is recommended for stent improvements and ureteric length determinations. PMID:26317082

  14. Digital air leak monitoring after lobectomy for primary lung cancer in patients with moderate COPD: can a fast-tracking algorithm reduce postoperative costs and complications?

    PubMed

    Filosso, P L; Ruffini, E; Solidoro, P; Molinatti, M; Bruna, M C; Oliaro, A

    2010-06-01

    Prolonged air leaks remain one of the most important complication after pulmonary resection. The aim of this study was to test a new fast-track chest tube removal protocol using a new drainage system, which digitally records postoperative air leaks, compared to the traditional one, with subjective visual air leak assessment. Patients with moderate COPD undergoing lobectomy for primary lung cancer at the Department of Thoracic Surgery of the University of Torino were randomised in two groups with different chest drainage systems and different removal protocols: in Group A the drainage was removed after digitally recordered measurement of air leaks; in Group B the tube was removed according to the air leaks visualization by bubbling in the water column. The following variables were evaluated: first and second drainage removal day; overall hospital length of stay; overall hospitalization costs. First and second drainages were removed sooner in those patients with the digital drainage system. An earlier drainage removal is associated with significative reduction in hospital length of stay and overall hospitalization costs. The digital and continuous air leak measurement reduces the hospital length of stay by a more accurate and reproductive air leaks measurement. Further studies are mandatory to corroborate our preliminary results.

  15. Spatial distribution of galls caused by Aculus tetanothrix (Acari: Eriophyoidea) on arctic willows.

    PubMed

    Kuczyński, Lechosław; Skoracka, Anna

    2005-01-01

    The distribution of galls caused by Aculus tetanothrix (Acari: Eriophyoidea) on three Salix species was studied. The factors influencing this distribution were analysed, i.e. willow species, study area and shoot length. Spatial pattern of gall distribution within the shoot was also examined. The study was conducted in Russia, Kola Peninsula. Densities of galls caused by A. tetanothrix differed significantly among willow species. Considerably higher gall density was recorded in the White Sea coast than in the Khibiny Mountains. This may be explained by the influence of a milder maritime climate that favors mite occurrence compared to a harsh and variable mountain climate that limits mite abundance. There was no relationship between the gall density and the shoot length. The highest density of galls was recorded on the inner offshoots; within the offshoot, there was a maximum density on the fifth leaf. This pattern was repeatable for all shoots studied, independent of the study area, willow species and length of shoots, suggesting the optimal conditions for A. tetanothrix exist on leaves in the middle part of a shoot. This distribution pattern may be an effect of the trade-off between the costs and benefits resulting from leaf quality and mite movement along the shoot. This hypothesis, however, needs to be tested experimentally.

  16. Factors Affecting the Length of Stay in the Intensive Care Unit: Our Clinical Experience

    PubMed Central

    Sengul Samanci, Nilay; Akkoc, İbrahim; Yucetas, Esma; Cebeci, Egemen; Ozturk, Savas

    2018-01-01

    Background and Aim Long hospital days in intensive care unit (ICU) due to life-threatening diseases are increasing in the world. The primary goal in ICU is to decrease length of stay in order to improve the quality of medical care and reduce cost. The aim of our study is to identify and categorize the factors associated with prolonged stays in ICU. Materials and Method We retrospectively analyzed 3925 patients. We obtained the patients' demographic, clinical, diagnostic, and physiologic variables; mortality; lengths of stay by examining the intensive care unit database records. Results The mean age of the study was 61.6 ± 18.9 years. The average length of stay in intensive care unit was 10.2 ± 25.2 days. The most common cause of hospitalization was because of multiple diseases (19.5%). The length of stay was positively correlated with urea, creatinine, and sodium. It was negatively correlated with uric acid and hematocrit levels. Length of stay was significantly higher in patients not operated on than in patients operated on (p < 0.001). Conclusion Our study showed a significantly increased length of stay in patients with cardiovascular system diseases, multiple diseases, nervous system diseases, and cerebrovascular diseases. Moreover we showed that when urea, creatinine, and sodium values increase, in parallel the length of stay increases. PMID:29750174

  17. The Pleistocene Eastern Equatorial Pacific: Insights from a New Carnegie Platform Stratigraphic Record

    NASA Astrophysics Data System (ADS)

    Gwizd, S.; Lea, D. W.

    2016-12-01

    Renewed interest in a classic Eastern Equatorial Pacific paleoceanographic site at 3° 35.85' S, 83° 57.79' W, previous site of cores V19-29 and TR163-31, prompted a re-coring in 2009 using the recently developed CDH giant piston coring system on cruise KNR195-5. Giant piston core CDH-36 (3225 m depth, 42.61 m length) nearly triples the length of previous cores at this site. When spliced together with companion multicore MC-34A (0.36 m length), these two cores generate continuous stratigraphy throughout most of the middle Pleistocene, and include recognized stratigraphic tie points ash layer "L" (Ninkovich and Shackleton, 1975) and the extinction of pink G. ruber. A new age model utilizing Bayesian analysis of 17 N. dutertrei radiocarbon dates in MC-34A and the top 3.4 m of CDH-36, and alignment of a new CDH-36 δ18O record with the LR04 benthic stack (Lisiecki and Raymo, 2005), demonstrates that this new "Carnegie Platform" (CP) record extends from 0 to 720 ka (MIS 18), tripling the timescale of previous studies, with an average sedimentation rate of 7 cm/kyr. The CP C. wuellerstorfi δ18O and δ13C records reveal strong consistencies in timing and extent of glacial and interglacial episodes with previously studied regional records. Coarse fraction percentage (%CF) ([coarse fraction/bulk dry sample] * 100) is also evaluated throughout the CP core in order to qualitatively assess dissolution cycles. The CP %CF dataset primarily records Pleistocene dissolution cycles, yet exhibits variability representative of potential local bathymetric and hydrographic effects. The timing of %CF cyclicity is consistent with processes which affect basin-wide calcium carbonate dissolution cycles, including changes in terrestrial carbon input to the oceans and changes in water mass ventilation (Shackleton, 1977; Toggweiler et al., 2006; Sexton and Barker, 2012). Establishing the stratigraphy of the CP record provides the first step towards a more thorough and extended analysis of this important Eastern Equatorial Pacific site.

  18. Hair coat characteristics and thermophysiological stress response of Nguni and Boran cows raised under hot environmental conditions

    NASA Astrophysics Data System (ADS)

    Katiyatiya, C. L. F.; Muchenje, V.

    2017-12-01

    Breed, age, coat colour, month and temperature humidity index (THI) influence on body weight (W), body condition score (BCS), thermophysiological variables (rectal temperature (Tr), skin temperature (Tsk)) and hair length was studied in Nguni ( n = 19) and Boran ( n = 16). As a result of this study, breed influenced W, BCS and Tsk on the neck and belly ( P < 0.05). The BCS and W of Nguni cows were higher than the Boran cows. Hair length of both breeds increased from February to August. The THI influenced thermophysiological variables ( P < 0.05). Increased Tr for both breeds was recorded in February and April, respectively ( P < 0.05). Month influenced Tsk and June recorded lower values ( P < 0.05). Younger cows (3-8 years) had lower weight and high Tr and Tsk ( P < 0.05). Nguni cows had high neck and thurl temperatures in June while Boran cows had the highest in August ( P < 0.05). Red, dun and white-black Boran cows had increased BCS. Nguni cows with red, fawn and white cows had high BCS. Fawn-coloured Nguni cows and white-brown Boran cows had the more weight than cows with other colours compared in the study. White-red Nguni and Boran cows recorded the highest Tr. For Nguni cows, neck and belly temperatures were significantly ( P < 0.001) correlated to thurl temperature. Boran cows had significant ( P < 0.001) correlations for THI and neck, belly and thurl temperatures. The current study found that Nguni cows were more adapted to the prevailing bioclimatic changes. However, Boran cows have the potential of performing well under heat stress conditions over time.

  19. Comparison of different parameters for recording sagittal maxillo mandibular relation using natural head posture: A cephalometric study

    PubMed Central

    Singh, Ashish Kumar; Ganeshkar, Sanjay V.; Mehrotra, Praveen; Bhagchandani, Jitendra

    2013-01-01

    Background: Commonly used parameters for anteroposterior assessment of the jaw relationship includes several analyses such as ANB, NA-Pog, AB-NPog, Wits appraisal, Harvold's unit length difference, Beta angle. Considering the fact that there are several parameters (with different range and values) which account for sagittal relation, and still the published literature for comparisons and correlation of these measurements is scarce. Therefore, the objective of this study was to correlate these values in subjects of Indian origin. Materials and Methods: The sample consisted of fifty adult individuals (age group 18-26 years) with equal number of males and females. The selection criteria included subjects with no previous history of orthodontic and/or orthognathic surgical treatment; orthognathic facial profile; Angle's Class I molar relation; clinical Frankfort Mandibular plane angle FMA of 30±5° and no gross facial asymmetry. The cephalograms were taken in natural head position (NHP). Seven sagittal skeletal parameters were measured in the cephalograms and subjected to statistical evaluation with Wits reading on the true horizontal as reference. A correlation coefficient analysis was done to assess the significance of association between these variables. Results: ANB angle showed statistically significant correlation for the total sample, though the values were insignificant for the individual groups and therefore may not be very accurate. Wits appraisal was seen to have a significant correlation only in the female sample group. Conclusions: If cephalograms cannot be recorded in a NHP, then the best indicator for recording A-P skeletal dimension would be angle AB-NPog, followed by Harvold's unit length difference. However, considering biologic variability, more than one reading should necessarily be used to verify the same. PMID:24987638

  20. Age estimation using pulp/tooth area ratio in maxillary canines-A digital image analysis.

    PubMed

    Juneja, Manjushree; Devi, Yashoda B K; Rakesh, N; Juneja, Saurabh

    2014-09-01

    Determination of age of a subject is one of the most important aspects of medico-legal cases and anthropological research. Radiographs can be used to indirectly measure the rate of secondary dentine deposition which is depicted by reduction in the pulp area. In this study, 200 patients of Karnataka aged between 18-72 years were selected for the study. Panoramic radiographs were made and indirectly digitized. Radiographic images of maxillary canines (RIC) were processed using a computer-aided drafting program (ImageJ). The variables pulp/root length (p), pulp/tooth length (r), pulp/root width at enamel-cementum junction (ECJ) level (a), pulp/root width at mid-root level (c), pulp/root width at midpoint level between ECJ level and mid-root level (b) and pulp/tooth area ratio (AR) were recorded. All the morphological variables including gender were statistically analyzed to derive regression equation for estimation of age. It was observed that 2 variables 'AR' and 'b' contributed significantly to the fit and were included in the regression model, yielding the formula: Age = 87.305-480.455(AR)+48.108(b). Statistical analysis indicated that the regression equation with selected variables explained 96% of total variance with the median of the residuals of 0.1614 years and standard error of estimate of 3.0186 years. There is significant correlation between age and morphological variables 'AR' and 'b' and the derived population specific regression equation can be potentially used for estimation of chronological age of individuals of Karnataka origin.

  1. Improved Fuzzy Logic System to Evaluate Milk Electrical Conductivity Signals from On-Line Sensors to Monitor Dairy Goat Mastitis.

    PubMed

    Zaninelli, Mauro; Tangorra, Francesco Maria; Costa, Annamaria; Rossi, Luciana; Dell'Orto, Vittorio; Savoini, Giovanni

    2016-07-13

    The aim of this study was to develop and test a new fuzzy logic model for monitoring the udder health status (HS) of goats. The model evaluated, as input variables, the milk electrical conductivity (EC) signal, acquired on-line for each gland by a dedicated sensor, the bandwidth length and the frequency and amplitude of the first main peak of the Fourier frequency spectrum of the recorded milk EC signal. Two foremilk gland samples were collected from eight Saanen goats for six months at morning milking (lactation stages (LS): 0-60 Days In Milking (DIM); 61-120 DIM; 121-180 DIM), for a total of 5592 samples. Bacteriological analyses and somatic cell counts (SCC) were used to define the HS of the glands. With negative bacteriological analyses and SCC < 1,000,000 cells/mL, glands were classified as healthy. When bacteriological analyses were positive or showed a SCC > 1,000,000 cells/mL, glands were classified as not healthy (NH). For each EC signal, an estimated EC value was calculated and a relative deviation was obtained. Furthermore, the Fourier frequency spectrum was evaluated and bandwidth length, frequency and amplitude of the first main peak were identified. Before using these indexes as input variables of the fuzzy logic model a linear mixed-effects model was developed to evaluate the acquired data considering the HS, LS and LS × HS as explanatory variables. Results showed that performance of a fuzzy logic model, in the monitoring of mammary gland HS, could be improved by the use of EC indexes derived from the Fourier frequency spectra of gland milk EC signals recorded by on-line EC sensors.

  2. Parental smoking during pregnancy shortens offspring's legs.

    PubMed

    Żądzińska, E; Kozieł, S; Borowska-Strugińska, B; Rosset, I; Sitek, A; Lorkiewicz, W

    2016-12-01

    One of the most severe detrimental environmental factors acting during pregnancy is foetal smoke exposure. The aim of this study was to assess the effect of maternal, paternal and parental smoking during pregnancy on relative leg length in 7- to 10-year-old children. The research conducted in the years 2001-2002 included 978 term-born children, 348 boys and 630 girls, at the age of 7-10 years. Information concerning the birth weight of a child was obtained from the health records of the women. Information about the mother's and the father's smoking habits during pregnancy and about the mothers' education level was obtained from a questionnaire. The influence of parental smoking on relative leg length, controlled for age, sex, birth weight and the mother's education, as a proxy measure of socioeconomic status, and controlled for an interaction between sex and birth weight, was assessed by an analysis of covariance, where relative leg length was the dependent variable, smoking and sex were the independent variables, and birth weight as well as the mother's education were the covariates. Three separate analyses were run for the three models of smoking habits during pregnancy: the mother's smoking, the father's smoking and both parents' smoking. Only both parents' smoking showed a significant effect on relative leg length of offspring. It is probable that foetal hypoxia caused by carbon monoxide contained in smoke decelerated the growth of the long bones of foetuses. Copyright © 2016 Elsevier GmbH. All rights reserved.

  3. Using Different Standardized Methods for Species Identification: A Case Study Using Beaks from Three Ommastrephid Species

    NASA Astrophysics Data System (ADS)

    Hu, Guanyu; Fang, Zhou; Liu, Bilin; Chen, Xinjun; Staples, Kevin; Chen, Yong

    2018-04-01

    The cephalopod beak is a vital hard structure with a stable configuration and has been widely used for the identification of cephalopod species. This study was conducted to determine the best standardization method for identifying different species by measuring 12 morphological variables of the beaks of Illex argentinus, Ommastrephes bartramii, and Dosidicus gigas that were collected by Chinese jigging vessels. To remove the effects of size, these morphometric variables were standardized using three methods. The average ratios of the upper beak morphological variables and upper crest length of O. bartramii and D. gigas were found to be greater than those of I. argentinus. However, for lower beaks, only the average of LRL (lower rostrum length)/ LCL (lower crest length), LRW (lower rostrum width)/ LCL, and LLWL (lower lateral wall length)/ LCL of O. bartramii and D. gigas were greater than those of I. argentinus. The ratios of beak morphological variables and crest length were found to be all significantly different among the three species ( P < 0.001). Among the three standardization methods, the correct classification rate of stepwise discriminant analysis (SDA) was the highest using the ratios of beak morphological variables and crest length. Compared with hood length, the correct classification rate was slightly higher when using beak variables standardized by crest length using an allometric model. The correct classification rate of the lower beak was also found to be greater than that of the upper beak. This study indicates that the ratios of beak morphological variables to crest length could be used for interspecies and intraspecies identification. Meanwhile, the lower beak variables were found to be more effective than upper beak variables in classifying beaks found in the stomachs of predators.

  4. Intracranial EEG fluctuates over months after implanting electrodes in human brain

    NASA Astrophysics Data System (ADS)

    Ung, Hoameng; Baldassano, Steven N.; Bink, Hank; Krieger, Abba M.; Williams, Shawniqua; Vitale, Flavia; Wu, Chengyuan; Freestone, Dean; Nurse, Ewan; Leyde, Kent; Davis, Kathryn A.; Cook, Mark; Litt, Brian

    2017-10-01

    Objective. Implanting subdural and penetrating electrodes in the brain causes acute trauma and inflammation that affect intracranial electroencephalographic (iEEG) recordings. This behavior and its potential impact on clinical decision-making and algorithms for implanted devices have not been assessed in detail. In this study we aim to characterize the temporal and spatial variability of continuous, prolonged human iEEG recordings. Approach. Intracranial electroencephalography from 15 patients with drug-refractory epilepsy, each implanted with 16 subdural electrodes and continuously monitored for an average of 18 months, was included in this study. Time and spectral domain features were computed each day for each channel for the duration of each patient’s recording. Metrics to capture post-implantation feature changes and inflexion points were computed on group and individual levels. A linear mixed model was used to characterize transient group-level changes in feature values post-implantation and independent linear models were used to describe individual variability. Main results. A significant decline in features important to seizure detection and prediction algorithms (mean line length, energy, and half-wave), as well as mean power in the Berger and high gamma bands, was observed in many patients over 100 d following implantation. In addition, spatial variability across electrodes declines post-implantation following a similar timeframe. All selected features decreased by 14-50% in the initial 75 d of recording on the group level, and at least one feature demonstrated this pattern in 13 of the 15 patients. Our findings indicate that iEEG signal features demonstrate increased variability following implantation, most notably in the weeks immediately post-implant. Significance. These findings suggest that conclusions drawn from iEEG, both clinically and for research, should account for spatiotemporal signal variability and that properly assessing the iEEG in patients, depending upon the application, may require extended monitoring.

  5. Stable isotope records of convection variability in the West Pacific Warm Pool from fast-growing stalagmites

    NASA Astrophysics Data System (ADS)

    Maupin, C. R.; Partin, J. W.; Quinn, T. M.; Shen, C.; Lin, K.; Taylor, F. W.; Sinclair, D. J.; Banner, J. L.

    2010-12-01

    The potential response of the tropical Pacific to ongoing anthropogenic global warming conditions is informed by instrumental data, model predictions and climate proxy evidence. However, these distinct lines of evidence lead to opposing predictions in terms of the nature of interannual (ENSO) variability in a warming world. Interpreted in an ENSO framework, warming in the tropical Pacific may elicit a zonally asymmetrical response and lead to an intensified Walker Circulation (more ‘La Niña - like’). Alternatively, discrepancies in the increasing rates of latent heat flux and rainfall due to warming conditions may in fact reduce Walker Circulation (more ‘El Niño - like’). However, in order for such a framework to be useful in the context of future climate change, some knowledge of the natural variability in the strength of Walker Circulation components is required. The extant instrumental data are not of sufficient temporal length to fully assess the spectrum of natural variability in such climate components. Oxygen isotope records from tropical speleothems have been successfully used to document the nature of precessional forcing on precipitation and atmospheric circulation patterns throughout the tropics. Typical stalagmite growth rates of 10-100 μm yr-1 allow decadally resolved records of δ18O variability on time scales of centuries to millennia and beyond. Here we present the initial results from calcite stalagmites of heretofore unprecedented growth rates (~1-4 mm yr-1) in a cave in northwest Guadalcanal, Solomon Islands (~9°S, 160°E). These stalagmites have been absolutely dated by U-Th techniques and indicate stalagmite growth spanning ~1650 to 2010 CE. The δ18O records from stalagmites provide evidence for changes in convection in the equatorial WPWP region of the SPCZ: the rising limb of the Pacific Walker Circulation, and therefore provide critical insight into changes in zonal atmospheric circulation across the Pacific.

  6. Fournier's gangrene: an analysis of repeated surgical debridement.

    PubMed

    Chawla, Sam N; Gallop, Christina; Mydlo, Jack H

    2003-05-01

    We wanted to determine if there was a difference in outcome for those patients with Fournier's disease who underwent numerous debridements as opposed to only one initial debridement. The records of 19 patients with the diagnosis of Fournier's gangrene were reviewed retrospectively at our institution. Special attention was placed on demographic data, primary managing service, as well as wound cultures, and the number and timing of surgical debridements. Patients were also classified by a collection of variables at presentation and given a score named the Fournier's Severity Index. We utilised the Fournier's Severity Index (FSI) as developed by Laor et al. which included a number of vital sign data as well as laboratory values collected at admission in the emergency room. The average FSI was 9.1 ranging from 0 to 15. The mean FSI of survivors was 8.6 versus 12.4 of non-survivors. The surgical management of this disease process was also critically examined. The average number of repeated debridements was 3.5 ranging from 1 to 8. Both the FSI and the number of debridements were attempted to be used to predict outcome. Outcome was measured in the variables length of stay (days) and survival. A regression analysis revealed the number of debridements to be positively related to the length of stay (LOS). This was the opposite as expected at the beginning of the study. Also FSI was not predictive of LOS. Fournier's gangrene is a disease process with a wide variability in presentation. The FSI does give some indication about the likelihood of survival based on variables which can be recorded upon presentation. It also provides an efficient way to characterize the acuity of presentation and compare patients. While the repeated nature of debridements may be considered the accepted standard of care in these patients, this was not found to be predictive of outcome.

  7. [Difference and distance between the central and thinnest points of the cornea: impact of refractive state, age and ocular side].

    PubMed

    Steinberg, J; Kohl, C; Katz, T; Richard, G; Linke, S J

    2014-04-01

    The aim of the study was to quantify the difference in corneal thickness between the central and thinnest points (∆PachyZ-PachyD), the distance between the center of the cornea and its thinnest point (vector length PachyD) and to explore the impact of refractive state, age and ocular side. This was a multicenter, retrospective, cross-sectional study and medical records of 16,872 eyes were reviewed. The Orbscan® (Bausch and Lomb) procedure was used for pachymetry and keratometry. The results showed that ∆PachyZ-PachyD and vector length PachyD were higher in hyperopic eyes (∆PachyZ-PachyD: 11.99 ± 12.08 µm, vector length PachyD: 0.85 ± 0.44 mm) compared to myopic eyes (∆PachyZ-PachyD: 9.2 ± 7.86 µm, vector length PachyD: 0.7 ± 0.37 mm; p < 0.001). Refractive state, age and ocular side demonstrated an independent, statistically significant impact on ∆PachyZ-PachyD and vector length PachyD. As a result of the significant impact of refractive state, age and ocular side on ∆PachyZ-PachyD and vector length PachyD, these variables should be considered in a normative data collection.

  8. Early nutritional support is associated with decreased length of hospitalization in dogs with septic peritonitis: A retrospective study of 45 cases (2000-2009).

    PubMed

    Liu, Debra T; Brown, Dorothy C; Silverstein, Deborah C

    2012-08-01

    To determine whether the timing and route of nutritional support strategy affect length of hospitalization in dogs with naturally occurring septic peritonitis. Retrospective study encompassing cases from 2000 to 2009. University teaching hospital. Forty-five dogs that survived septic peritonitis. None. Nutritional strategy for each dog was categorized as either enteral nutrition (EN: free choice voluntary eating or assisted tube feeding) or central parenteral nutrition (CPN). Early nutritional support was defined as consistent caloric intake initiated within 24 hours postoperatively. Consistent caloric intake occurring after 24 hours was defined as delayed nutritional support. Data reflective of nutritional status included body condition score, serum albumin concentration, and duration of inappetence before and during hospitalization. Body weight change from the beginning to the end of hospitalization was calculated. A modified Survival Prediction Index 2 score was calculated for each dog at admission. Additional clinical data recorded for comparison of illness severity included indicators of severe inflammation (eg, presence of toxic changes in neutrophils and immature neutrophils), coagulopathy (eg, prolonged prothrombin time and activated partial thromboplastin time), the use of vasopressors and blood transfusions, and presence of concurrent illnesses. Nutrition-related complications were classified as mechanical, metabolic, or septic complications. Multivariate linear regression analyses were used to determine the relationship of nutritional strategy with hospitalization length, while considering the presence of nutrition-related complications, the nutritional status- and illness severity-related variables. While controlling for other variables, dogs that received early nutrition had significantly shorter hospitalization length (by 1.6 days). No statistically significant association was found between route of nutrition and hospitalization length. The presence of concurrent illnesses and nutrition-related metabolic complications were also associated with longer hospitalization length (by 2.1 and 2.4 days, respectively). Early nutritional support in dogs with septic peritonitis is associated with a shorter hospitalization length. © Veterinary Emergency and Critical Care Society 2012.

  9. Predictors of length of stay after urogynecological surgery at a tertiary referral center.

    PubMed

    Gagnon, Louise-Helene; Tang, Selphee; Brennand, Erin

    2017-02-01

    The primary objective of this study was to determine significant predictors of length of stay (LOS) beyond the first postoperative day after urogynecological surgery. A single-center retrospective cohort study was conducted in 2015. Our study population included women who underwent inpatient pelvic reconstructive surgery. The primary outcome was LOS beyond the first postoperative day. A logistic regression analysis explored the relationship between 11 selected predictor variables [age, body mass index (BMI), American Society of Anesthesiologists (ASA) score, distance from home to hospital, length of surgery, anesthesia during surgery, route of surgical approach, trial of void recordings, choice of bladder protocol, presence of concomitant sling, surgeon], and LOS. Two hundred and sixty-three patients were included in this study. A logistic regression analysis identified route of surgery and trial of void recordings as the two statistically significant predictors of stay beyond the first postoperative day. The odds of LOS after laparoscopic or open surgery compared with vaginal surgery increased more than fivefold [laparoscopic vs. vaginal approach odds ratio (OR) 5.04, 95 % confidence interval (CI) 1.95-13.03; laparotomy vs. vaginal OR 15.56, 95 % CI 1.77-136.77] and more than threefold for a prolonged pass of the bladder protocol compared with an immediate pass (OR 3.25, 95 % CI 1.54-6.87). Our study identified route of surgery and trial of void recordings as the two predictors with the greatest impact on LOS beyond the first postoperative day. Our results warrant a larger follow-up study.

  10. Ice Core Records of Recent Northwest Greenland Climate

    NASA Astrophysics Data System (ADS)

    Osterberg, E. C.; Wong, G. J.; Ferris, D.; Lutz, E.; Howley, J. A.; Kelly, M. A.; Axford, Y.; Hawley, R. L.

    2014-12-01

    Meteorological station data from NW Greenland indicate a 3oC temperature rise since 1990, with most of the warming occurring in fall and winter. According to remote sensing data, the NW Greenland ice sheet (GIS) and coastal ice caps are responding with ice mass loss and margin retreat, but the cryosphere's response to previous climate variability is poorly constrained in this region. We are developing multi-proxy records (lake sediment cores, ice cores, glacial geologic data, glaciological models) of Holocene climate change and cryospheric response in NW Greenland to improve projections of future ice loss and sea level rise in a warming climate. As part of our efforts to develop a millennial-length ice core paleoclimate record from the Thule region, we collected and analyzed snow pit samples and short firn cores (up to 21 m) from the coastal region of the GIS (2Barrel site; 76.9317o N, 63.1467o W, 1685 m el.) and the summit of North Ice Cap (76.938o N, 67.671o W, 1273 m el.) in 2011, 2012 and 2014. The 2Barrel ice core record has statistically significant relationships with regional spring and fall Baffin Bay sea ice extent, summertime temperature, and annual precipitation. Here we evaluate relationships between the 2014 North Ice Cap firn core glaciochemical record and climate variability from regional instrumental stations and reanalysis datasets. We compare the coastal North Ice Cap record to more inland records from 2Barrel, Camp Century and NEEM to evaluate spatial and elevational gradients in recent NW Greenland climate change.

  11. Association of udder traits with single nucleotide polymorphisms in crossbred Bos indicus-Bos taurus cows.

    PubMed

    Tolleson, M W; Gill, C A; Herring, A D; Riggs, P K; Sawyer, J E; Sanders, J O; Riley, D G

    2017-06-01

    The size, support, and health of udders limit the productive life of beef cows, especially those with background, because, in general, such cows have a reputation for problems with udders. Genomic association studies of bovine udder traits have been conducted in dairy cattle and recently in Continental European beef breeds but not in cows with background. The objective of this study was to determine associations of SNP and udder support scores, teat length, and teat diameter in half (Nellore), half (Angus) cows. Udders of cows ( = 295) born from 2003 to 2007 were evaluated for udder support and teat length and diameter ( = 1,746 records) from 2005 through 2014. These included a subjective score representing udder support (values of 1 indicated poorly supported, pendulous udders and values of 9 indicated very well-supported udders) and lengths and diameters of individual teats in the 4 udder quarters as well as the average. Cows were in full-sibling or half-sibling families. Residuals for each trait were produced from repeated records models with cow age category nested within birth year of cows. Those residuals were averaged to become the dependent variables for genomewide association analyses. Regression analyses of those dependent variables included genotypic values as explanatory variables for 34,980 SNP from a commercially available array and included the genomic relationship matrix. Fifteen SNP loci on BTA 5 were associated (false discovery rate controlled at 0.05) with udder support score. One of those was also detected as associated with average teat diameter. Three of those 15 SNP were located within genes, including one each in (), (), and (). These are notable for their functional role in some aspect of mammary gland formation or health. Other candidate genes for these traits in the vicinity of the SNP loci include () and (). Because these were detected in Nellore-Angus crossbred cows, which typically have very well-formed udders with excellent support across their productive lives, similar efforts in other breeds should be completed, because that may facilitate further refinement of genomic regions responsible for variation in udder traits important in multiple breeds.

  12. An Indirect Method to Measure Abutment Screw Preload: A Pilot Study Based on Micro-CT Scanning.

    PubMed

    Rezende, Carlos Eduardo E; Griggs, Jason Alan; Duan, Yuanyuan; Mushashe, Amanda M; Nolasco, Gisele Maria Correr; Borges, Ana Flávia Sanches; Rubo, José Henrique

    2015-01-01

    This study aimed to measure the preload in different implant platform geometries based on micro-CT images. External hexagon (EH) implants and Morse Tapered (MT) implants (n=5) were used for the preload measurement. The abutment screws were scanned in micro-CT to obtain their virtual models, which were used to record their initial length. The abutments were screwed on the implant with a 20 Ncm torque and the set composed by implant, abutment screw and abutment were taken to the micro-CT scanner to obtain virtual slices of the specimens. These slices allowed the measurement of screw lengths after torque application and based on the screw elongation. Preload values were calculated using the Hooke's Law. The preloads of both groups were compared by independent t-test. Removal torque of each specimen was recorded. To evaluate the accuracy of the micro-CT technique, three rods with known lengths were scanned and the length of their virtual model was measured and compared with the original length. One rod was scanned four times to evaluate the measuring method variation. There was no difference between groups for preload (EH = 461.6 N and MT = 477.4 N), but the EH group showed higher removal torque values (13.8 ± 4.7 against 8.2 ± 3.6 N cm for MT group). The micro-CT technique showed a variability of 0.053% and repeatability showed an error of 0.23 to 0.28%. Within the limitations of this study, there was no difference between external hexagon and Morse taper for preload. The method using micro-CT may be considered for preload calculation.

  13. Factorial correspondence analysis of fear-related behaviour traits in Japanese quail.

    PubMed

    Mignon-Grasteau, S; Roussot, O; Delaby, C; Faure, J M.; Mills, A; Leterrier, C; Guéméné, D; Constantin, P; Mills, M; Lepape, G; Beaumont, C

    2003-02-28

    Factorial correspondence analysis was performed on 341 quails from a F2 cross between two lines divergently selected on the duration of tonic immobility over 29 generations. Several fear- or stress-related traits were recorded, i.e. tonic immobility duration, number of inductions needed to induce tonic immobility, open-field behaviour (time spent walking, latency before first movement and number of defecations), asymmetry of tibia lengths and corticosterone concentration after restraint stress. Variables were categorised in classes and analysed by factorial correspondence analysis. The first axis was mostly described by open-field behaviour, and the second by tonic immobility traits (duration of tonic immobility and number of inductions), which showed that these behaviours were almost independent. No relationship was found between axes of the factorial correspondence analysis and corticosterone concentration or asymmetry of tibia lengths, showing that these variables reflected other characteristics of stress susceptibility than those described by tonic immobility and open-field behaviour. These results show that reaction to stress of quails is a multidimensional trait and cannot be summarised by one trait.

  14. Risk factors related to methicillin-resistant Staphylococcus aureus infection among inpatients at Prof. dr. R. D. Kandou general hospital Manado

    NASA Astrophysics Data System (ADS)

    Utomo, H. T.; Nugroho, A.; Harijanto, P. N.

    2018-03-01

    Methicillin-resistant Staphylococcus aureus (MRSA) presents nosocomial infection problemsin hospitals. Identification of risk factors related to MRSA infection is a concern among healthcare provider. A retrospective case-control study was conducted to identify MRSA infection proportion among isolates, also to identify risk factors amonginpatients at Prof. dr.R. D. Kandou General Hospital, Manado. Data were from themedical record, from patient’s culture isolateswith positive Staphylococcus aureus infection from January-December 2015. Case subject isolated cultures of MRSA and control subject isolated cultures of non-MRSA. Bivariate analysis were performed in 10 independent variables (age, length of stay, prior use of antibiotics before cultures, history of HIV infection, prior use of corticosteroid, history of malignancy, history of chronic disease, prior use of medical tools (catheter, ventilator, etc), history of invasive medical procedure, history of hospitalization before). All variables with a p-value<0.05 were into multivariate analysis with forwarding stepwise logistic regression. Mean subjects age were 48.13 ± 2.05 years old and length of stay were 8.65 ± 0.25 days, and only prior antibiotic use-variable were considered statistically significant (p = 0.017; OR 1.889; 95%CI 1.595 – 2.238).

  15. Web-based questionnaires to assess perinatal outcome proved to be valid.

    PubMed

    van Gelder, Marleen M H J; Vorstenbosch, Saskia; Derks, Lineke; Te Winkel, Bernke; van Puijenbroek, Eugène P; Roeleveld, Nel

    2017-10-01

    The objective of this study was to validate a Web-based questionnaire completed by the mother to assess perinatal outcome used in a prospective cohort study. For 882 women with an estimated date of delivery between February 2012 and February 2015 who participated in the PRegnancy and Infant DEvelopment (PRIDE) Study, we compared data on pregnancy outcome, including mode of delivery, plurality, gestational age, birth weight and length, head circumference, birth defects, and infant sex, from Web-based questionnaires administered to the mothers 2 months after delivery with data from obstetric records. For continuous variables, we calculated intraclass correlation coefficients (ICCs) with 95% confidence intervals (CIs), whereas sensitivity and specificity were determined for categorical variables. We observed only very small differences between the two methods of data collection for gestational age (ICC, 0.91; 95% CI, 0.90-0.92), birth weight (ICC, 0.96; 95% CI, 0.95-0.96), birth length (ICC, 0.90; 95% CI, 0.87-0.92), and head circumference (ICC, 0.88; 95% CI, 0.80-0.93). Agreement between the Web-based questionnaire and obstetric records was high as well, with sensitivity ranging between 0.86 (termination of pregnancy) and 1.00 (four outcomes) and specificity between 0.96 (term birth) and 1.00 (nine outcomes). Our study provides evidence that Web-based questionnaires could be considered as a valid complementary or alternative method of data collection. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. A pulse-forming network for particle path visualization. [at Ames Aeromechanics Water Tunnel Facility

    NASA Technical Reports Server (NTRS)

    Mcalister, K. W.

    1981-01-01

    A procedure is described for visualizing nonsteady fluid flow patterns over a wide velocity range using discrete nonluminous particles. The paramount element responsible for this capability is a pulse-forming network with variable inductance that is used to modulate the discharge of a fixed amount of electrical energy through a xenon flashtube. The selectable duration of the resultant light emission functions as a variable shutter so that particle path images of constant length can be recorded. The particles employed as flow markers are hydrogen bubbles that are generated by electrolysis in a water tunnel. Data are presented which document the characteristics of the electrical circuit and establish the relation of particle velocity to both section inductance and film exposure.

  17. Effects of UV-B radiation on leaf hair traits of invasive plants-Combining historical herbarium records with novel remote sensing data.

    PubMed

    Václavík, Tomáš; Beckmann, Michael; Cord, Anna F; Bindewald, Anja M

    2017-01-01

    Ultraviolet-B (UV-B) radiation is a key but under-researched environmental factor that initiates diverse responses in plants, potentially affecting their distribution. To date, only a few macroecological studies have examined adaptations of plant species to different levels of UV-B. Here, we combined herbarium specimens of Hieracium pilosella L. and Echium vulgare L. with a novel UV-B dataset to examine differences in leaf hair traits between the plants' native and alien ranges. We analysed scans of 336 herbarium specimens using standardized measurements of leaf area, hair density (both species) and hair length (H. pilosella only). While accounting for other bioclimatic variables (i.e. temperature, precipitation) and effects of herbivory, we examined whether UV-B exposure explains the variability and geographical distribution of these traits in the native (Northern Hemisphere) vs. the alien (Southern Hemisphere) range. UV-B explained the largest proportion of the variability and geographical distribution of hair length in H. pilosella (relative influence 67.1%), and hair density in E. vulgare (66.2%). Corresponding with higher UV-B, foliar hairs were 25% longer for H. pilosella and 25% denser for E. vulgare in records from the Southern as compared to those from the Northern Hemisphere. However, focusing on each hemisphere separately or controlling for its effect in a regression analysis, we found no apparent influence of UV-B radiation on hair traits. Thus, our findings did not confirm previous experimental studies which suggested that foliar hairs may respond to higher UV-B intensities, presumably offering protection against detrimental levels of radiation. We cannot rule out UV-B radiation as a possible driver because UV-B radiation was the only considered variable that differed substantially between the hemispheres, while bioclimatic conditions (e.g. temperature, precipitation) and other considered variables (herbivory damage, collection date) were at similar levels. However, given that either non-significant or inconclusive relationships were detected within hemispheres, alternative explanations of the differences in foliar hairs are more likely, including the effects of environment, genotypes or herbivory.

  18. Variability of total step activity in children with cerebral palsy: influence of definition of a day on participant retention within the study.

    PubMed

    Wilson, Nichola C; Mudge, Suzie; Stott, N Susan

    2016-08-20

    Activity monitoring is important to establish accurate daily physical activity levels in children with cerebral palsy (CP). However, few studies address issues around inclusion or exclusion of step count data; in particular, how a valid day should be defined and what impact different lengths of monitoring have on retention of participant data within a study. This study assessed how different 'valid day' definitions influenced inclusion of participant data in final analyses and the subsequent variability of the data. Sixty-nine children with CP were fitted with a StepWatch™ Activity Monitor and instructed to wear it for a week. Data analysis used two broad definitions of a day, based on either number of steps in a 24 h monitoring period or the number of hours of recorded activity in a 24 h monitoring period. Eight children either did not use the monitor, or used it for only 1 day. The remaining 61 children provided 2 valid days of monitoring defined as >100 recorded steps per 24 h period and 55 (90 %) completed 2 valid days of monitoring with ≥10 h recorded activity per 24 h period. Performance variability in daily step count was lower across 2 days of monitoring when a valid day was defined as ≥10 h recorded activity per 24 h period (ICC = 0.765) and, higher when the definition >100 recorded steps per 24 h period (ICC = 0.62). Only 46 participants (75 %) completed 5 days of monitoring with >100 recorded steps per 24 h period and only 23 (38 %) achieved 5 days of monitoring with ≥10 h recorded activity per 24 h period. Datasets of participants who functioned at GMFCS level II were differentially excluded when the criteria for inclusion in final analysis was 5 valid days of ≥10 h recorded activity per 24 h period, leaving datasets available for only 8 of 32 participant datasets retained in the study. We conclude that changes in definition of a valid day have significant impacts on both inclusion of participant data in final analysis and measured variability of total step count.

  19. Comparison of ophthalmic measurements obtained via high-frequency ultrasound imaging in four species of snakes.

    PubMed

    Hollingsworth, Steven R; Holmberg, Bradford J; Strunk, Anneliese; Oakley, Alicia D; Sickafoose, Leann M; Kass, Philip H

    2007-10-01

    To measure the dimensions of the eyes of living snakes by use of high-frequency ultrasound imaging and correlate those measurements with age, length, and weight. Animals-14 clinically normal snakes. Species, age, length, weight, and horizontal spectacle diameter were recorded, and each snake underwent physical and ophthalmic examinations; ultrasonographic examination of both eyes was performed by use of a commercially available ultrasound unit and a 50-MHz transducer. Ultrasonographic measurements included spectacle thickness, subspectacular space depth, corneal thickness, anterior chamber depth, lens thickness, vitreous cavity depth, and globe length. All measurements were made along the visual axis. 2 corn snakes, 5 California king snakes, 1 gopher snake, and 6 ball pythons were examined. There were no significant differences within or between the species with regard to mean spectacle thickness, corneal thickness, or subspectacular space depth. However, mean horizontal spectacle diameter, anterior chamber depth, and axial globe length differed among the 4 species; for each measurement, ball pythons had significantly larger values than California king snakes. Spectacle thickness, subspectacular space depth, and corneal thickness were similar among the species of snake examined and did not vary significantly with age, length, or weight. Measurements of these dimensions can potentially serve as baseline values to evaluate snakes of these species with a retained spectacle, subspectacular abscess, or subspectacular fluid accumulation. Anterior chamber depth and axial length appeared variable among species, but axial length did not vary with age, length, or weight in the species studied.

  20. Toward Capturing Momentary Changes of Heart Rate Variability by a Dynamic Analysis Method

    PubMed Central

    Zhang, Haoshi; Zhu, Mingxing; Zheng, Yue; Li, Guanglin

    2015-01-01

    The analysis of heart rate variability (HRV) has been performed on long-term electrocardiography (ECG) recordings (12~24 hours) and short-term recordings (2~5 minutes), which may not capture momentary change of HRV. In this study, we present a new method to analyze the momentary HRV (mHRV). The ECG recordings were segmented into a series of overlapped HRV analysis windows with a window length of 5 minutes and different time increments. The performance of the proposed method in delineating the dynamics of momentary HRV measurement was evaluated with four commonly used time courses of HRV measures on both synthetic time series and real ECG recordings from human subjects and dogs. Our results showed that a smaller time increment could capture more dynamical information on transient changes. Considering a too short increment such as 10 s would cause the indented time courses of the four measures, a 1-min time increment (4-min overlapping) was suggested in the analysis of mHRV in the study. ECG recordings from human subjects and dogs were used to further assess the effectiveness of the proposed method. The pilot study demonstrated that the proposed analysis of mHRV could provide more accurate assessment of the dynamical changes in cardiac activity than the conventional measures of HRV (without time overlapping). The proposed method may provide an efficient means in delineating the dynamics of momentary HRV and it would be worthy performing more investigations. PMID:26172953

  1. Appointment length, psychiatrists' communication behaviors, and medication management appointment adherence.

    PubMed

    Cruz, Mario; Roter, Debra L; Cruz, Robyn F; Wieland, Melissa; Larson, Susan; Cooper, Lisa A; Pincus, Harold Alan

    2013-09-01

    The authors explored the relationship between critical elements of medication management appointments (appointment length, patient-centered talk, and positive nonverbal affect among providers) and patient appointment adherence. The authors used an exploratory, cross-sectional design employing quantitative analysis of 83 unique audio recordings of split treatment medication management appointments for 46 African-American and 37 white patients with 24 psychiatrists at four ambulatory mental health clinics. All patients had a diagnosis of depression. Data collected included demographic information; Patient Health Questionnaire-9 scores for depression severity; psychiatrist verbal and nonverbal communication behaviors during medication management appointments, identified by the Roter Interaction Analysis System during analysis of audio recordings; and appointment adherence. Bivariate analyses were employed to identify covariates that might influence appointment adherence. Generalized estimating equations (GEEs) were employed to assess the relationship between appointment length, psychiatrist patient-centered talk, and positive voice tone ratings and patient appointment adherence, while adjusting for covariates and the clustering of observations within psychiatrists. Wald chi square analyses were used to test whether all or some variables significantly influenced appointment adherence. GEE revealed a significant relationship between positive voice tone ratings and appointment adherence (p=.03). Chi square analyses confirmed the hypothesis of a positive and significant relationship between appointment adherence and positive voice tone ratings (p=.03) but not longer visit length and more patient-centered communication. The nonverbal conveyance of positive affect was associated with greater adherence to medication management appointments by depressed patients. These findings potentially have important implications for communication skills training and adherence research.

  2. Effect of sampling rate and record length on the determination of stability and control derivatives

    NASA Technical Reports Server (NTRS)

    Brenner, M. J.; Iliff, K. W.; Whitman, R. K.

    1978-01-01

    Flight data from five aircraft were used to assess the effects of sampling rate and record length reductions on estimates of stability and control derivatives produced by a maximum likelihood estimation method. Derivatives could be extracted from flight data with the maximum likelihood estimation method even if there were considerable reductions in sampling rate and/or record length. Small amplitude pulse maneuvers showed greater degradation of the derivative maneuvers than large amplitude pulse maneuvers when these reductions were made. Reducing the sampling rate was found to be more desirable than reducing the record length as a method of lessening the total computation time required without greatly degrading the quantity of the estimates.

  3. Correlations of Handgrip Strength with Selected Hand-Arm-Anthropometric Variables in Indian Inter-university Female Volleyball Players

    PubMed Central

    Koley, Shyamal; Pal Kaur, Satinder

    2011-01-01

    Purpose The purpose of this study was to estimate the dominant handgrip strength and its correlations with some hand and arm anthropometric variables in 101 randomly selected Indian inter-university female volleyball players aged 18-25 years (mean age 20.52±1.40) from six Indian universities. Methods Three anthropometric variables, i.e. height, weight, BMI, two hand anthropometric variables, viz. right and left hand width and length, four arm anthropometric variables, i.e. upper arm length, lower arm length, upper extremity length, upper arm circumference and dominant right and non-dominant handgrip strength were measured among Indian inter-university female volleyball players by standard anthropometric techniques. Results The findings of the present study indicated that Indian female volleyball players had higher mean values in eleven variables and lesser mean values in two variables than their control counterparts, showing significant differences (P<0.032-0.001) in height (t=2.63), weight (t=8.66), left hand width (t=2.10), left and right hand length (t=9.99 and 10.40 respectively), right upper arm length (t=8.48), right forearm length (t=5.41), dominant (right) and non-dominant (left) handgrip strength (t=9.37 and 6.76 respectively). In female volleyball players, dominant handgrip strength had significantly positive correlations (P=0.01) with all the variables studied. Conclusion It may be concluded that dominant handgrip strength had strong positive correlations with all the variables studied in Indian inter-university female volleyball players. PMID:22375242

  4. Is Moderate Intensity Cycling Sufficient to Induce Cardiorespiratory and Biomechanical Modifications of Subsequent Running?

    PubMed

    Walsh, Joel A; Dawber, James P; Lepers, Romuald; Brown, Marc; Stapley, Paul J

    2017-04-01

    Walsh, JA, Dawber, JP, Lepers, R, Brown, M, and Stapley, PJ. Is moderate intensity cycling sufficient to induce cardiorespiratory and biomechanical modifications of subsequent running? J Strength Cond Res 31(4): 1078-1086, 2017-This study sought to determine whether prior moderate intensity cycling is sufficient to influence the cardiorespiratory and biomechanical responses during subsequent running. Cardiorespiratory and biomechanical variables measured after moderate intensity cycling were compared with control running at the same intensity. Eight highly trained, competitive triathletes completed 2 separate exercise tests; (a) a 10-minute control run (no prior cycling) and, (b) a 30-minute transition run (TR) (preceded by 20-minute of variable cadence cycling, i.e., run versus cycle-run). Respiratory, breathing frequency (fb), heart rate (HR), cost of running (Cr), rate constant, stride length, and stride frequency variables were recorded, normalized, and quantified at the mean response time (MRT), third minute, 10th minute (steady state), and overall for the control run (CR) and TR. Cost of running increased (p ≤ 0.05) at all respective times during the TR. The V[Combining Dot Above]E/V[Combining Dot Above]CO2 and respiratory exchange ratio (RER) were significantly (p < 0.01) elevated at the MRT and 10th minute of the TR. Furthermore, overall mean increases were recorded for Cr, V[Combining Dot Above]E, V[Combining Dot Above]E/V[Combining Dot Above]CO2, RER, fb (p < 0.01), and HR (p ≤ 0.05) during the TR. Rate constant values for oxygen uptake were significantly different between CR and TR (0.48 ± 0.04 vs. 0.89 ± 0.15; p < 0.01). Stride length decreased across all recorded points during the TR (p ≤ 0.05) and stride frequency increased at the MRT and 3 minutes (p < 0.01). The findings suggest that at moderate intensity, prior cycling influences the cardiorespiratory response during subsequent running. Furthermore, prior cycling seems to have a sustained effect on the Cr during subsequent running.

  5. In vivo and in vitro heterogeneity of segment length changes in the semimembranosus muscle of the toad

    PubMed Central

    Ahn, A N; Monti, R J; Biewener, A A

    2003-01-01

    Many studies examine sarcomere dynamics in single fibres or length–tension dynamics in whole muscles in vivo or in vitro, but few studies link the various levels of organisation. To relate data addressing in vitro muscle segment behaviour with in vivo whole muscle behaviour during locomotion, we measured in vivo strain patterns of muscle segments using three sonomicrometry crystals implanted along a fascicle of the semimembranosus muscle in the American toad (Bufo americanus; n = 6) during hopping. The centre crystal emitted an ultrasonic signal, while the outer crystals received the signal allowing the instantaneous measurement of lengths from two adjacent muscle segments. On the first day, we recorded from the central and distal segments. On the second day of recordings, the most distal crystal was moved to a proximal position to record from a proximal segment and the same central segment. When the toads hopped a distance of two body lengths, the proximal and central segments strained −15.1 ± 6.1 and −14.0 ± 4.9 % (i.e. shortening), respectively. Strain of the distal segment, however, was significantly lower and more variable in pattern, often lengthening before shortening during a hop. From rest length, the distal segment initially lengthened by 2.6 ± 2.0 % before shortening by 6.5 ± 3.2 % at the same hop distance. Under in vitro conditions, the central segment always shortened more than the distal segment, except when passively cycled, during which the segments strained similarly. When the whole muscle was cycled sinusoidally and stimulated phasically in vitro, the two adjacent segments strained in opposite directions over much (up to 34 %) of the cycle. These differences in strain amplitude and direction imply that two adjacent segments can not only produce and/or absorb varying amounts of mechanical energy, but can also operate on different regions of their force–length and force–velocity relationships when activated by the same neural signal. Understanding regional differences in contractile dynamics within muscles is therefore important to linking our understanding of sarcomere behaviour with whole muscle behaviour during locomotion. PMID:12717006

  6. Fluxes all of the time? A primer on the temporal representativeness of FLUXNET

    NASA Astrophysics Data System (ADS)

    Chu, Housen; Baldocchi, Dennis D.; John, Ranjeet; Wolf, Sebastian; Reichstein, Markus

    2017-02-01

    FLUXNET, the global network of eddy covariance flux towers, provides the largest synthesized data set of CO2, H2O, and energy fluxes. To achieve the ultimate goal of providing flux information "everywhere and all of the time," studies have attempted to address the representativeness issue, i.e., whether measurements taken in a set of given locations and measurement periods can be extrapolated to a space- and time-explicit extent (e.g., terrestrial globe, 1982-2013 climatological baseline). This study focuses on the temporal representativeness of FLUXNET and tests whether site-specific measurement periods are sufficient to capture the natural variability of climatological and biological conditions. FLUXNET is unevenly representative across sites in terms of the measurement lengths and potentials of extrapolation in time. Similarity of driver conditions among years generally enables the extrapolation of flux information beyond measurement periods. Yet such extrapolation potentials are further constrained by site-specific variability of driver conditions. Several driver variables such as air temperature, diurnal temperature range, potential evapotranspiration, and normalized difference vegetation index had detectable trends and/or breakpoints within the baseline period, and flux measurements generally covered similar and biased conditions in those drivers. About 38% and 60% of FLUXNET sites adequately sampled the mean conditions and interannual variability of all driver conditions, respectively. For long-record sites (≥15 years) the percentages increased to 59% and 69%, respectively. However, the justification of temporal representativeness should not rely solely on the lengths of measurements. Whenever possible, site-specific consideration (e.g., trend, breakpoint, and interannual variability in drivers) should be taken into account.

  7. Factors contributing to practice variation in post-stroke rehabilitation.

    PubMed Central

    Lee, A J; Huber, J H; Stason, W B

    1997-01-01

    OBJECTIVE: To analyze geographic variability in the utilization and cost of post-stroke medical care using multiple linear regression. DATA SOURCES/STUDY SETTING: A 20 percent random sample of Medicare beneficiaries with an admission to an acute care hospital for stroke during the first six months of 1991, supplemented by data from their Medicare claims and beneficiary records, the Medicare Cost Reports for hospitals and nursing homes, and the Area Resource File. STUDY DESIGN: Weighted least squares regression is used to analyze variations in post-stroke practice patterns across 151 MSAs (Metropolitan Statistical Areas). Average post-stroke costs, utilization rates, and facility lengths of stay are regressed on patient and market characteristics. DATA COLLECTION/EXTRACTION METHODS: For a six-month post-stroke interval, beneficiary-level post-stroke costs and service utilization are averaged by MSA. Variables describing market conditions are then added to these MSA-level records. PRINCIPAL FINDINGS: Patient variables rarely explain more than a third of practice variation, and often they explain substantially less than that. Market variables (with some exception) tend to be relatively less important. Finally, one-half to two-thirds of the practice variation across MSAs is unexplained by the patient and market factors measured in our data. CONCLUSIONS: A substantial portion of inter-MSA variability in utilization and intensity of post-stroke rehabilitation services cannot be explained by differences in patient characteristics. Given the large practice differences observed across MSAs, it seems unlikely that unmeasured patient differences can account for much more of the practice differences. PMID:9180616

  8. Interannual Modulation of Subtropical Atlantic Boreal Summer Dust Variability by ENSO

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DeFlorio, Mike; Goodwin, Ian D.; Cayan, Dan

    2016-01-01

    Dust variability in the climate system has been studied for several decades, yet there remains an incomplete understanding of the dynamical mechanisms controlling interannual and decadal variations in dust transport. The sparseness of multi-year observational datasets has limited our understanding of the relationship between climate variations and atmospheric dust. We use available observations and a century-length fully coupled Community Earth System Model (CESM) simulation to show that the El Niño- Southern Oscillation (ENSO) exerts a control on North African dust transport during boreal summer. In CESM, this relationship is stronger over the dusty tropical North Atlantic than near Barbados, onemore » of the few sites having a multi-decadal observed record. During strong La Niña summers in CESM, a statistically significant increase in lower tropospheric easterly wind is associated with an increase in North African dust transport over the Atlantic. Barbados dust and Pacific SST variability are only weakly correlated in both observations and CESM, suggesting that other processes are controlling the crossbasin variability of dust. We also use our CESM simulation to show that the relationship between downstream North African dust transport and ENSO fluctuates on multidecadal timescales and may be modulated by the North Atlantic Oscillation (NAO). Our findings indicate that existing observations of dust over the tropical North Atlantic are not extensive enough to completely describe the variability of dust and dust transport, and demonstrate the importance of global models to supplement and interpret observational records.« less

  9. Increasing pressure ulcer rates and changes in delivery of care: a retrospective analysis at a University Clinic.

    PubMed

    Stausberg, Jürgen; Lehmann, Nils; Kröger, Knut; Maier, Irene; Schneider, Helmut; Niebel, Wolfgang

    2010-06-01

    To evaluate the relation between pressure ulcers and delivery of care. No decrease of pressure ulcer rates could be recognised in acute hospital care, despite intensive efforts in prevention. Furthermore, reports show increasing rates. Retrospective analysis of hospital data. The study included all inpatients from year 1 (2003/2004) and 4 (2006/2007) of the interdisciplinary decubitus project. Information on ulcers was recorded at admission, discharge and in case of new events. We analysed the effect of age, length of stay, operation and intensive care episode. In logistic regression, we used the existence of ulcers and the appearance of new ulcers as dependent variables. Parallel to a decrease in the number of inpatients, age, length of stay and operation frequency rose between 2003 and 2007. Higher age, longer length of stay, operation, intensive care episode and year 4 raise the odds for ulcers in univariate and with exception of operation in multivariate analyses. With exception of operation and year 4, the same variables raise the odds for new ulcers, too. The increase of pressure ulcer frequency could be related to changes in delivery of care. The adverse event pressure ulcer will become more important in hospital care. There is no decrease in pressure ulcer rates, albeit enormous efforts in prevention. Hospital care has been facing changes in case mix. Age, length of stay and intensive care episodes are related to increasing ulcer rates at a University Clinic. Nursing management has to be aware of additional workload for pressure ulcer management in the future.

  10. The influence of gait speed on the stability of walking among the elderly.

    PubMed

    Fan, Yifang; Li, Zhiyu; Han, Shuyan; Lv, Changsheng; Zhang, Bo

    2016-06-01

    Walking speed is a basic factor to consider when walking exercises are prescribed as part of a training programme. Although associations between walking speed, step length and falling risk have been identified, the relationship between spontaneous walking pattern and falling risk remains unclear. The present study, therefore, examined the stability of spontaneous walking at normal, fast and slow speed among elderly (67.5±3.23) and young (21.4±1.31) individuals. In all, 55 participants undertook a test that involved walking on a plantar pressure platform. Foot-ground contact data were used to calculate walking speed, step length, pressure impulse along the plantar-impulse principal axis and pressure record of time series along the plantar-impulse principal axis. A forward dynamics method was used to calculate acceleration, velocity and displacement of the centre of mass in the vertical direction. The results showed that when the elderly walked at different speeds, their average step length was smaller than that observed among the young (p=0.000), whereas their anterior/posterior variability and lateral variability had no significant difference. When walking was performed at normal or slow speed, no significant between-group difference in cadence was found. When walking at a fast speed, the elderly increased their stride length moderately and their cadence greatly (p=0.012). In summary, the present study found no correlation between fast walking speed and instability among the elderly, which indicates that healthy elderly individuals might safely perform fast-speed walking exercises. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Detecting the propagation effect of terahertz wave inside the two-color femtosecond laser filament in the air

    NASA Astrophysics Data System (ADS)

    Zhao, J.; Zhang, X.; Li, S.; Liu, C.; Chen, Y.; Peng, Y.; Zhu, Y.

    2018-03-01

    In this work, to decide the existence of terahertz (THz) wave propagation effect, THz pulses emitted from a blocked two-color femtosecond laser filament with variable length were recorded by a standard electric-optic sampling setup. The phenomenon of temporal advance of the THz waveform's peak with the increasing filament length has been observed. Together with another method of knife-edge measurement which aims at directly retrieving the THz beam diameter, both the experimental approaches have efficiently indicated the same filament range within which THz wave propagated inside the plasma column. At last, a preliminary two-dimensional near-field scanning imaging of the THz spot inside the cross section of the filament has been suggested as the third way to determine the issue of THz wave propagation effect.

  12. Electrogram morphology recurrence patterns during atrial fibrillation.

    PubMed

    Ng, Jason; Gordon, David; Passman, Rod S; Knight, Bradley P; Arora, Rishi; Goldberger, Jeffrey J

    2014-11-01

    Traditional mapping of atrial fibrillation (AF) is limited by changing electrogram morphologies and variable cycle lengths. We tested the hypothesis that morphology recurrence plot analysis would identify sites of stable and repeatable electrogram morphology patterns. AF electrograms recorded from left atrial (LA) and right atrial (RA) sites in 19 patients (10 men; mean age 59 ± 10 years) before AF ablation were analyzed. Morphology recurrence plots for each electrogram recording were created by cross-correlation of each automatically detected activation with every other activation in the recording. A recurrence percentage, the percentage of the most common morphology, and the mean cycle length of activations with the most recurrent morphology were computed. The morphology recurrence plots commonly showed checkerboard patterns of alternating high and low cross-correlation values, indicating periodic recurrences in morphologies. The mean recurrence percentage for all sites and all patients was 38 ± 25%. The highest recurrence percentage per patient averaged 83 ± 17%. The highest recurrence percentage was located in the RA in 5 patients and in the LA in 14 patients. Patients with sites of shortest mean cycle length of activations with the most recurrent morphology in the LA and RA had ablation failure rates of 25% and 100%, respectively (hazard ratio 4.95; P = .05). A new technique to characterize electrogram morphology recurrence demonstrated that there is a distribution of sites with high and low repeatability of electrogram morphologies. Sites with rapid activation of highly repetitive morphology patterns may be critical to sustaining AF. Further testing of this approach to map and ablate AF sources is warranted. Copyright © 2014 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  13. Elongation as a factor in artefacts of humans and other animals: an Acheulean example in comparative context.

    PubMed

    Gowlett, J A J

    2013-11-19

    Elongation is a commonly found feature in artefacts made and used by humans and other animals and can be analysed in comparative study. Whether made for use in hand or beak, the artefacts have some common properties of length, breadth, thickness and balance point, and elongation can be studied as a factor relating to construction or use of a long axis. In human artefacts, elongation can be traced through the archaeological record, for example in stone blades of the Upper Palaeolithic (traditionally regarded as more sophisticated than earlier artefacts), and in earlier blades of the Middle Palaeolithic. It is now recognized that elongation extends to earlier Palaeolithic artefacts, being found in the repertoire of both Neanderthals and more archaic humans. Artefacts used by non-human animals, including chimpanzees, capuchin monkeys and New Caledonian crows show selection for diameter and length, and consistent interventions of modification. Both chimpanzees and capuchins trim side branches from stems, and appropriate lengths of stave are selected or cut. In human artefacts, occasional organic finds show elongation back to about 0.5 million years. A record of elongation achieved in stone tools survives to at least 1.75 Ma (million years ago) in the Acheulean tradition. Throughout this tradition, some Acheulean handaxes are highly elongated, usually found with others that are less elongated. Finds from the million-year-old site of Kilombe and Kenya are given as an example. These findings argue that the elongation need not be integral to a design, but that artefacts may be the outcome of adjustments to individual variables. Such individual adjustments are seen in animal artefacts. In the case of a handaxe, the maker must balance the adjustments to achieve a satisfactory outcome in the artefact as a whole. It is argued that the need to make decisions about individual variables within multivariate objects provides an essential continuity across artefacts made by different species.

  14. Episiotomy increases perineal laceration length in primiparous women.

    PubMed

    Nager, C W; Helliwell, J P

    2001-08-01

    The aim of this study was to determine the clinical factors that contribute to posterior perineal laceration length. A prospective observational study was performed in 80 consenting, mostly primiparous women with term pregnancies. Posterior perineal lacerations were measured immediately after delivery. Numerous maternal, fetal, and operator variables were evaluated against laceration length and degree of tear. Univariate and multivariate regression analyses were performed to evaluate laceration length and parametric clinical variables. Nonparametric clinical variables were evaluated against laceration length by the Mann-Whitney U test. A multivariate stepwise linear regression equation revealed that episiotomy adds nearly 3 cm to perineal lacerations. Tear length was highly associated with the degree of tear (R = 0.86, R(2) = 0.73) and the risk of recognized anal sphincter disruption. None of 35 patients without an episiotomy had a recognized anal sphincter disruption, but 6 of 27 patients with an episiotomy did (P <.001). Body mass index was the only maternal or fetal variable that showed even a slight correlation with laceration length (R = 0.30, P =.04). Episiotomy is the overriding determinant of perineal laceration length and recognized anal sphincter disruption.

  15. The Effects of Respondents’ Consent to be Recorded on Interview Length and Data Quality in a National Panel Study

    PubMed Central

    McGonagle, Katherine A.; Brown, Charles; Schoeni, Robert F.

    2014-01-01

    Recording interviews is a key feature of quality control protocols for most survey organizations. We examine the effects on interview length and data quality of a new protocol adopted by a national panel study. The protocol recorded a randomly chosen one-third of all interviews digitally, although all respondents were asked for permission to record their interview, and interviewers were blind to whether or not interviews were recorded. We find that the recording software slowed the interview slightly. Interviewer knowledge that the interview may be recorded improved data quality, but this knowledge also increased the length of the interview. Interviewers with higher education and performance ratings were less reactive to the new recording protocol. Survey managers may face a trade-off between higher data quality and longer interviews when determining recording protocols. PMID:26550000

  16. Stable oxygen and hydrogen isotope analyses of bowhead whale baleen as biochemical recorders of migration and arctic environmental change

    NASA Astrophysics Data System (ADS)

    deHart, Pieter A. P.; Picco, Candace M.

    2015-06-01

    An analysis of the stable isotopes of oxygen (δ18O) and hydrogen (δD) was used to examine the linkage between sea ice concentration and the migration of western arctic bowhead whales (Balaena mysticetus; WABW). We compared δ18O and δD variability along the length of WABW baleen with isotopic values of zooplankton prey from different WABW habitat, with published δ13C and δ15N data, and with historical sea ice records. Zooplankton signatures varied widely (δ18O = -13‰-56‰; δD = -220‰ to -75‰), with regional separation between winter (Bering Sea) and summer (eastern Beaufort Sea) habitats of WABW observable in δD. The δ18O and δD of WABW varied significantly along the length of baleen (δ18O = 8-18‰; δD = -180 to -80‰), confirming seasonal migration and reflecting distinct regional dietary variation in isotopes. WABW migration appears to have varied concomitant with temporal sea ice concentration (SIC) changes; in years with high SIC, the difference in δD of WABW baleen between seasonal habitats was significantly greater than low SIC periods. This work shows that SIC is not only a determinant of habitat accessibility for WABW, but baleen may also be a record of historical SIC and Arctic climate.

  17. Rising climate variability and synchrony in North Pacific ecosystems

    NASA Astrophysics Data System (ADS)

    Black, Bryan

    2017-04-01

    Rising climate variability and synchrony in North Pacific ecosystems Evidence is growing that climate variability of the northeast Pacific Ocean has increased over the last century, culminating in such events as the record-breaking El Niño years 1983, 1998, and 2016 and the unusually persistent 2014/15 North Pacific Ocean heat wave known as "The Blob." Of particular concern is that rising variability could increase synchrony within and among North Pacific ecosystems, which could reduce the diversity of biological responses to climate (i.e. the "portfolio effect"), diminish resilience, and leave populations more prone to extirpation. To test this phenomenon, we use a network of multidecadal fish otolith growth-increment chronologies that were strongly correlated to records of winter (Jan-Mar) sea level. These biological and physical datasets spanned the California Current through the Gulf of Alaska. Synchrony was quantified as directional changes in running (31-year window) mean pairwise correlation within sea level and then within otolith time series. Synchrony in winter sea level at the nine stations with the longest records has increased by more than 40% over the 1950-2015 interval. Likewise, synchrony among the eight longest otolith chronologies has increased more than 100% over a comparable time period. These directional changes in synchrony are highly unlikely due to chance alone, as confirmed by comparing trends in observed data to those in simulated data (n = 10,000 iterations) with time series of identical number, length, and autocorrelation. Ultimately, this trend in rising synchrony may be linked to increased impacts of the El Niño Southern Oscillation (ENSO) on mid-latitude ecosystems of North America, and may therefore reflect a much broader, global-scale signature.

  18. A multichannel model-based methodology for extubation readiness decision of patients on weaning trials.

    PubMed

    Casaseca-de-la-Higuera, Pablo; Simmross-Wattenberg, Federico; Martín-Fernández, Marcos; Alberola-López, Carlos

    2009-07-01

    Discontinuation of mechanical ventilation is a challenging task that involves a number of subtle clinical issues. The gradual removal of the respiratory support (referred to as weaning) should be performed as soon as autonomous respiration can be sustained. However, the prediction rate of successful extubation is still below 25% based on previous studies. Construction of an automatic system that provides information on extubation readiness is thus desirable. Recent works have demonstrated that the breathing pattern variability is a useful extubation readiness indicator, with improving performance when multiple respiratory signals are jointly processed. However, the existing methods for predictor extraction present several drawbacks when length-limited time series are to be processed in heterogeneous groups of patients. In this paper, we propose a model-based methodology for automatic readiness prediction. It is intended to deal with multichannel, nonstationary, short records of the breathing pattern. Results on experimental data yield an 87.27% of successful readiness prediction, which is in line with the best figures reported in the literature. A comparative analysis shows that our methodology overcomes the shortcomings of so far proposed methods when applied to length-limited records on heterogeneous groups of patients.

  19. Temporal trends of mercury concentrations in Wisconsin walleye (Sander vitreus), 1982-2005.

    PubMed

    Rasmussen, Paul W; Schrank, Candy S; Campfield, Patrick A

    2007-11-01

    The Wisconsin Department of Natural Resources has monitored mercury (Hg) in several species of fish since the early 1970s primarily for fish consumption advisory purposes. We selected skin-on fillets of walleye (Sander vitreus) from inland lakes collected over the years 1982-2005 to assess temporal trends of Hg concentrations. While individual lakes are of interest, sample sizes, and unbalanced collections across fish lengths, seasons, or years prevent estimates of temporal trends of walleye Hg concentrations within most lakes. We evaluated temporal trends over all lakes using mixed effects models (3,024 records from 421 lakes). Relationships between Hg concentrations and a suite of lake chemistry, morphometry, and other variables were also explored. Hg concentrations generally increased with walleye length but the relationship varied among lakes. The best-fitting mixed effects models suggested that the overall rate of change in walleye Hg across all lakes in the dataset varied with latitude. Hg in walleye decreased 0.5% per year in northern lakes, increased 0.8% in southern lakes, and remained constant in middle latitude lakes over the period of 1982-2005. Season of collection was also an important predictor variable. Hg concentrations were highest in walleye captured in the spring and lowest in the fall. Other variables such as gender, lake area, and total alkalinity were also important predictors.

  20. Multiple plant-wax compounds record differential sources and ecosystem structure in large river catchments

    NASA Astrophysics Data System (ADS)

    Hemingway, Jordon D.; Schefuß, Enno; Dinga, Bienvenu Jean; Pryer, Helena; Galy, Valier V.

    2016-07-01

    The concentrations, distributions, and stable carbon isotopes (δ13C) of plant waxes carried by fluvial suspended sediments contain valuable information about terrestrial ecosystem characteristics. To properly interpret past changes recorded in sedimentary archives it is crucial to understand the sources and variability of exported plant waxes in modern systems on seasonal to inter-annual timescales. To determine such variability, we present concentrations and δ13C compositions of three compound classes (n-alkanes, n-alcohols, n-alkanoic acids) in a 34-month time series of suspended sediments from the outflow of the Congo River. We show that exported plant-dominated n-alkanes (C25-C35) represent a mixture of C3 and C4 end members, each with distinct molecular distributions, as evidenced by an 8.1 ± 0.7‰ (±1σ standard deviation) spread in δ13C values across chain-lengths, and weak correlations between individual homologue concentrations (r = 0.52-0.94). In contrast, plant-dominated n-alcohols (C26-C36) and n-alkanoic acids (C26-C36) exhibit stronger positive correlations (r = 0.70-0.99) between homologue concentrations and depleted δ13C values (individual homologues average ⩽-31.3‰ and -30.8‰, respectively), with lower δ13C variability across chain-lengths (2.6 ± 0.6‰ and 2.0 ± 1.1‰, respectively). All individual plant-wax lipids show little temporal δ13C variability throughout the time-series (1σ ⩽ 0.9‰), indicating that their stable carbon isotopes are not a sensitive tracer for temporal changes in plant-wax source in the Congo basin on seasonal to inter-annual timescales. Carbon-normalized concentrations and relative abundances of n-alcohols (19-58% of total plant-wax lipids) and n-alkanoic acids (26-76%) respond rapidly to seasonal changes in runoff, indicating that they are mostly derived from a recently entrained local source. In contrast, a lack of correlation with discharge and low, stable relative abundances (5-16%) indicate that n-alkanes better represent a catchment-integrated signal with minimal response to discharge seasonality. Comparison to published data on other large watersheds indicates that this phenomenon is not limited to the Congo River, and that analysis of multiple plant-wax lipid classes and chain lengths can be used to better resolve local vs. distal ecosystem structure in river catchments.

  1. Importance of record length with respect to estimating the 1-percent chance flood

    USGS Publications Warehouse

    Feaster, Toby D.

    2010-01-01

    U.S. Geological Survey (USGS) streamflow gages have been established in every State in the Nation, Puerto Rico, and the Trust Territory of the Pacific Islands. From these st reamflow records, estimates of the magnitude and frequency of floods are often developed and used to design transportation and water- conveyance structures to protect lives and property, and to determine flood-insurance rates. Probably the most recognizable flood statistic computed from USGS stream gaging records is the 1- percent (%) chance flood; better known has the 100-year flood. By definition, this is a flood that has a 1% chance of occurring in any given year. The 1% chance flood is a statistical estimate that can be significantly influenced by length of record and extreme flood events captured in that record. Consequently, it is typically recommended that flood statistics be updated on some regular interval such as every 10 years. This paper examines the influence of record length on the 1% chance flood for the Broad River in Georgia and the substantial difference that can occur in the estimate based on record length and the hydrologic conditions under which that record was collected. 

  2. North Atlantic Oscillation Drives Regional Greenland Glacier Volume During the 20th Century

    NASA Astrophysics Data System (ADS)

    Bjork, A. A.; Aagaard, S.; Hallander, A. M.; Khan, S. A.; Box, J. E.; Kjeldsen, K. K.; Larsen, N. K.; Korsgaard, N. J.; Cappelen, J.; Colgan, W. T.; Machguth, H.; Andresen, C. S.; Kjaer, K. H.

    2016-12-01

    While most areas of the Greenland ice sheet have undergone rapid mass loss since c. 1990, the central eastern section of the ice sheet has advanced and gained mass. This contrasting regional trend has been attributed to positive surface mass balance (SMB) in the absence of significant dynamic mass loss. To constrain the atypical behavior in this region, we mapped glacier length fluctuations of nearly 200 peripheral glaciers and ice caps (PGICs) over a 103-year period, and compare the results with c. 150 new glacier length records from central west Greenland. We demonstrate that the regional response in ice volume is closely correlated to changes in precipitation, governed by circulation patterns associated with the North Atlantic Oscillation (NAO) and secondarily influenced by temperature forcing in certain periods. More broadly, we find that the NAO contributes to contrasting precipitation variability in East and West Greenland, where it appears to be responsible for at least 10% and more than 25%, respectively, of the variability in ice sheet accumulation rate. This east-west asymmetry, which influences both LGICs and the ice sheet, illustrates how substantial uncertainty in NAO projections directly contributes to uncertainty in mass balance projections.

  3. Differences in Pedaling Technique in Cycling: A Cluster Analysis.

    PubMed

    Lanferdini, Fábio J; Bini, Rodrigo R; Figueiredo, Pedro; Diefenthaeler, Fernando; Mota, Carlos B; Arndt, Anton; Vaz, Marco A

    2016-10-01

    To employ cluster analysis to assess if cyclists would opt for different strategies in terms of neuromuscular patterns when pedaling at the power output of their second ventilatory threshold (PO VT2 ) compared with cycling at their maximal power output (PO MAX ). Twenty athletes performed an incremental cycling test to determine their power output (PO MAX and PO VT2 ; first session), and pedal forces, muscle activation, muscle-tendon unit length, and vastus lateralis architecture (fascicle length, pennation angle, and muscle thickness) were recorded (second session) in PO MAX and PO VT2 . Athletes were assigned to 2 clusters based on the behavior of outcome variables at PO VT2 and PO MAX using cluster analysis. Clusters 1 (n = 14) and 2 (n = 6) showed similar power output and oxygen uptake. Cluster 1 presented larger increases in pedal force and knee power than cluster 2, without differences for the index of effectiveness. Cluster 1 presented less variation in knee angle, muscle-tendon unit length, pennation angle, and tendon length than cluster 2. However, clusters 1 and 2 showed similar muscle thickness, fascicle length, and muscle activation. When cycling at PO VT2 vs PO MAX , cyclists could opt for keeping a constant knee power and pedal-force production, associated with an increase in tendon excursion and a constant fascicle length. Increases in power output lead to greater variations in knee angle, muscle-tendon unit length, tendon length, and pennation angle of vastus lateralis for a similar knee-extensor activation and smaller pedal-force changes in cyclists from cluster 2 than in cluster 1.

  4. The Reliability and Validity of Measures of Gait Variability in Community-Dwelling Older Adults

    PubMed Central

    Brach, Jennifer S.; Perera, Subashan; Studenski, Stephanie; Newman, Anne B.

    2009-01-01

    Objective To examine the test-retest reliability and concurrent validity of variability of gait characteristics. Design Cross-sectional study. Setting Research laboratory. Participants Older adults (N=558) from the Cardiovascular Health Study. Interventions Not applicable. Main Outcome Measures Gait characteristics were measured using a 4-m computerized walkway. SD determined from the steps recorded were used as the measures of variability. Intraclass correlation coefficients (ICC) were calculated to examine test-retest reliability of a 4-m walk and two 4-m walks. To establish concurrent validity, the measures of gait variability were compared across levels of health, functional status, and physical activity using independent t tests and analysis of variances. Results Gait variability measures from the two 4-m walks demonstrated greater test-retest reliability than those from the single 4-m walk (ICC=.22–.48 and ICC=.40–.63, respectively). Greater step length and stance time variability were associated with poorer health, functional status and physical activity (P<.05). Conclusions Gait variability calculated from a limited number of steps has fair to good test-retest reliability and concurrent validity. Reliability of gait variability calculated from a greater number of steps should be assessed to determine if the consistency can be improved. PMID:19061741

  5. Last interglacial temperature seasonality reconstructed from tropical Atlantic corals

    NASA Astrophysics Data System (ADS)

    Brocas, William M.; Felis, Thomas; Obert, J. Christina; Gierz, Paul; Lohmann, Gerrit; Scholz, Denis; Kölling, Martin; Scheffers, Sander R.

    2016-09-01

    Reconstructions of last interglacial (LIG, MIS 5e, ∼127-117 ka) climate offer insights into the natural response and variability of the climate system during a period partially analogous to future climate change scenarios. We present well preserved fossil corals (Diploria strigosa) recovered from the southern Caribbean island of Bonaire (Caribbean Netherlands). These have been precisely dated by the 230Th/U-method to between 130 and 120 ka ago. Annual banding of the coral skeleton enabled construction of time windows of monthly resolved strontium/calcium (Sr/Ca) temperature proxy records. In conjunction with a previously published 118 ka coral record, our eight records of up to 37 years in length, cover a total of 105 years within the LIG period. From these, sea surface temperature (SST) seasonality and variability in the tropical North Atlantic Ocean is reconstructed. We detect similar to modern SST seasonality of ∼2.9 °C during the early (130 ka) and the late LIG (120-118 ka). However, within the mid-LIG, a significantly higher than modern SST seasonality of 4.9 °C (at 126 ka) and 4.1 °C (at 124 ka) is observed. These findings are supported by climate model simulations and are consistent with the evolving amplitude of orbitally induced changes in seasonality of insolation throughout the LIG, irrespective of wider climatic instabilities that characterised this period. The climate model simulations suggest that the SST seasonality changes documented in our LIG coral Sr/Ca records are representative of larger regions within the tropical North Atlantic. These simulations also suggest that the reconstructed SST seasonality increase during the mid-LIG is caused primarily by summer warming. A 124 ka old coral documents, for the first time, evidence of decadal SST variability in the tropical North Atlantic during the LIG, akin to that observed in modern instrumental records.

  6. Spatial correlation in precipitation trends in the Brazilian Amazon

    NASA Astrophysics Data System (ADS)

    Buarque, Diogo Costa; Clarke, Robin T.; Mendes, Carlos Andre Bulhoes

    2010-06-01

    A geostatistical analysis of variables derived from Amazon daily precipitation records (trends in annual precipitation totals, trends in annual maximum precipitation accumulated over 1-5 days, trend in length of dry spell, trend in number of wet days per year) gave results that are consistent with those previously reported. Averaged over the Brazilian Amazon region as a whole, trends in annual maximum precipitations were slightly negative, the trend in the length of dry spell was slightly positive, and the trend in the number of wet days in the year was slightly negative. For trends in annual maximum precipitation accumulated over 1-5 days, spatial correlation between trends was found to extend up to a distance equivalent to at least half a degree of latitude or longitude, with some evidence of anisotropic correlation. Time trends in annual precipitation were found to be spatially correlated up to at least ten degrees of separation, in both W-E and S-N directions. Anisotropic spatial correlation was strongly evident in time trends in length of dry spell with much stronger evidence of spatial correlation in the W-E direction, extending up to at least five degrees of separation, than in the S-N. Because the time trends analyzed are shown to be spatially correlated, it is argued that methods at present widely used to test the statistical significance of climate trends over time lead to erroneous conclusions if spatial correlation is ignored, because records from different sites are assumed to be statistically independent.

  7. Variability of Arctic Sea Ice as Determined from Satellite Observations

    NASA Technical Reports Server (NTRS)

    Parkinson, Claire L.

    1999-01-01

    The compiled, quality-controlled satellite multichannel passive-microwave record of polar sea ice now spans over 18 years, from November 1978 through December 1996, and is revealing considerable information about the Arctic sea ice cover and its variability. The information includes data on ice concentrations (percent areal coverages of ice), ice extents, ice melt, ice velocities, the seasonal cycle of the ice, the interannual variability of the ice, the frequency of ice coverage, and the length of the sea ice season. The data reveal marked regional and interannual variabilities, as well as some statistically significant trends. For the north polar ice cover as a whole, maximum ice extents varied over a range of 14,700,000 - 15,900,000 sq km, while individual regions experienced much greater percent variations, for instance, with the Greenland Sea having a range of 740,000 - 1,110,000 sq km in its yearly maximum ice coverage. In spite of the large variations from year to year and region to region, overall the Arctic ice extents showed a statistically significant, 2.80% / decade negative trend over the 18.2-year period. Ice season lengths, which vary from only a few weeks near the ice margins to the full year in the large region of perennial ice coverage, also experienced interannual variability, along with spatially coherent overall trends. Linear least squares trends show the sea ice season to have lengthened in much of the Bering Sea, Baffin Bay, the Davis Strait, and the Labrador Sea, but to have shortened over a much larger area, including the Sea of Okhotsk, the Greenland Sea, the Barents Sea, and the southeastern Arctic.

  8. Predictive equations for the estimation of body size in seals and sea lions (Carnivora: Pinnipedia)

    PubMed Central

    Churchill, Morgan; Clementz, Mark T; Kohno, Naoki

    2014-01-01

    Body size plays an important role in pinniped ecology and life history. However, body size data is often absent for historical, archaeological, and fossil specimens. To estimate the body size of pinnipeds (seals, sea lions, and walruses) for today and the past, we used 14 commonly preserved cranial measurements to develop sets of single variable and multivariate predictive equations for pinniped body mass and total length. Principal components analysis (PCA) was used to test whether separate family specific regressions were more appropriate than single predictive equations for Pinnipedia. The influence of phylogeny was tested with phylogenetic independent contrasts (PIC). The accuracy of these regressions was then assessed using a combination of coefficient of determination, percent prediction error, and standard error of estimation. Three different methods of multivariate analysis were examined: bidirectional stepwise model selection using Akaike information criteria; all-subsets model selection using Bayesian information criteria (BIC); and partial least squares regression. The PCA showed clear discrimination between Otariidae (fur seals and sea lions) and Phocidae (earless seals) for the 14 measurements, indicating the need for family-specific regression equations. The PIC analysis found that phylogeny had a minor influence on relationship between morphological variables and body size. The regressions for total length were more accurate than those for body mass, and equations specific to Otariidae were more accurate than those for Phocidae. Of the three multivariate methods, the all-subsets approach required the fewest number of variables to estimate body size accurately. We then used the single variable predictive equations and the all-subsets approach to estimate the body size of two recently extinct pinniped taxa, the Caribbean monk seal (Monachus tropicalis) and the Japanese sea lion (Zalophus japonicus). Body size estimates using single variable regressions generally under or over-estimated body size; however, the all-subset regression produced body size estimates that were close to historically recorded body length for these two species. This indicates that the all-subset regression equations developed in this study can estimate body size accurately. PMID:24916814

  9. Cross-sectional study of variables associated with length of stay and ICU need in open Roux-En-Y gastric bypass surgery for morbid obese patients: an exploratory analysis based on the Public Health System administrative database (Datasus) in Brazil.

    PubMed

    Asano, Elio Fernando; Rasera, Irineu; Shiraga, Elisabete Cristina

    2012-12-01

    This is an exploratory analysis of potential variables associated with open Roux-en-Y gastric bypass (RYGB) surgery hospitalization resource use pattern. Cross-sectional study based on an administrative database (DATASUS) records. Inclusion criteria were adult patients undergoing RYGB between Jan/2008 and Jun/2011. Dependent variables were length of stay (LoS) and ICU need. Independent variables were: gender, age, region, hospital volume, surgery at certified center of excellence (CoE) by the Surgical Review Corporation (SRC), teaching hospital, and year of hospitalization. Univariate and multivariate analysis (logistic regression for ICU need and linear regression for length of stay) were performed. Data from 13,069 surgeries were analyzed. In crude analysis, hospital volume was the most impactful variable associated with log-transformed LoS (1.312 ± 0.302 high volume vs. 1.670 ± 0.581 low volume, p < 0.001), whereas for ICU need it was certified CoE (odds ratio (OR), 0.016; 95% confidence interval (CI), 0.010-0.026). After adjustment by logistic regression, certified CoE remained as the strongest predictor of ICU need (OR, 0.011; 95% CI, 0.007-0.018), followed by hospital volume (OR, 3.096; 95% CI, 2.861-3.350). Age group, male gender, and teaching hospital were also significantly associated (p < 0.001). For log-transformed LoS, final model includes hospital volume (coefficient, -0.223; 95% CI, -0.250 to -0.196) and teaching hospital (coefficient, 0.375; 95% CI, 0.351-0.398). Region of Brazil was not associated with any of the outcomes. High-volume hospital was the strongest predictor for shorter LoS, whereas SRC certification was the strongest predictor of lower ICU need. Public health policies targeting an increase of efficiency and patient access to the procedure should take into account these results.

  10. Improving the diagnosis related grouping model's ability to explain length of stay of elderly medical inpatients by incorporating function-linked variables.

    PubMed

    Sahadevan, S; Earnest, A; Koh, Y L; Lee, K M; Soh, C H; Ding, Y Y

    2004-09-01

    This study first aimed to determine the adequacy of the Diagnosis Related Grouping (DRG) model's ability to explain (1) the variance in the actual length of stay (LOS) of elderly medical inpatients and (2) the LOS difference in the same cohort between the departments of Geriatric Medicine (GRM) and General Medicine (GM). We then looked at how these explanatory abilities of the DRG changed when patients' function-linked variables (ignored by DRG) were incorporated into the model. Basic demographic data of a consecutively hospitalised cohort of elderly medical inpatients from GRM and GM, as well as their actual LOS, discharge DRG codes [with their corresponding trimmed average length of stay (ALOS)] and selected function-linked variables (including premorbid functional status, change in functional profile during hospitalisation and number of therapists seen) were recorded. Beginning with ALOS, function-linked variables that were significantly associated with LOS were then added into two multiple liner regression models so as to quantify how the functional dimension improved the DRGs' abilities to explain LOS variances and interdepartmental LOS differences. Forward selection procedure was employed to determine the final models. For the interdepartmental analysis, the study sample was restricted to patients who shared common DRG codes. 114 GRM and 118 GM patients were studied. Trimmed ALOS alone explained 8% of the actual LOS variance. With the addition of function-linked variables, the adjusted R2 of the final model increased to 28%. Due to common code restrictions, the data of 79 GRM and 78 GM patients were available for the analysis of interdepartmental LOS differences. At the unadjusted stage, the median stay of GRM patients was 4.3 days longer than GM's and with adjustments made for the DRGs, this difference was reduced to 3.9 days. Additionally adjusting for the patients' functional features diminished the interdepartmental LOS discrepancy even further, to 2.1 days. This study demonstrates that for elderly medical inpatients, the incorporation of patients' functional status significantly improves the DRG model's ability to predict the patients' actual LOS as well as to explain interdepartmental LOS differences between GRM and GM.

  11. An investigation of the key parameters for predicting PV soiling losses

    DOE PAGES

    Micheli, Leonardo; Muller, Matthew

    2017-01-25

    One hundred and two environmental and meteorological parameters have been investigated and compared with the performance of 20 soiling stations installed in the USA, in order to determine their ability to predict the soiling losses occurring on PV systems. The results of this investigation showed that the annual average of the daily mean particulate matter values recorded by monitoring stations deployed near the PV systems are the best soiling predictors, with coefficients of determination ( R 2) as high as 0.82. The precipitation pattern was also found to be relevant: among the different meteorological parameters, the average length of drymore » periods had the best correlation with the soiling ratio. Lastly, a preliminary investigation of two-variable regressions was attempted and resulted in an adjusted R 2 of 0.90 when a combination of PM 2.5 and a binary classification for the average length of the dry period was introduced.« less

  12. Prediction of anthropometric foot characteristics in children.

    PubMed

    Morrison, Stewart C; Durward, Brian R; Watt, Gordon F; Donaldson, Malcolm D C

    2009-01-01

    The establishment of growth reference values is needed in pediatric practice where pathologic conditions can have a detrimental effect on the growth and development of the pediatric foot. This study aims to use multiple regression to evaluate the effects of multiple predictor variables (height, age, body mass, and gender) on anthropometric characteristics of the peripubescent foot. Two hundred children aged 9 to 12 years were recruited, and three anthropometric measurements of the pediatric foot were recorded (foot length, forefoot width, and navicular height). Multiple regression analysis was conducted, and coefficients for gender, height, and body mass all had significant relationships for the prediction of forefoot width and foot length (P < or = .05, r > or = 0.7). The coefficients for gender and body mass were not significant for the prediction of navicular height (P > or = .05), whereas height was (P < or = .05). Normative growth reference values and prognostic regression equations are presented for the peripubescent foot.

  13. Laparoscopic donor nephrectomy increases the supply of living donor kidneys: a center-specific microeconomic analysis.

    PubMed

    Kuo, P C; Johnson, L B

    2000-05-27

    A tenet of microeconomics is that new technology will shift the supply curve to the right. Laparoscopic donor nephrectomy (LDN) is a new technique for removal of living donor kidneys. Centers performing this procedure have noted an increased number of patients presenting for donor evaluation. This has not been previously studied. The records of all LDN performed from May 1998 to February 1999 were reviewed. The following variables were examined: sex, age, related vs. unrelated donation, estimated blood loss, i.v. analgesia, length of stay, and time out of work. Donors undergoing traditional open donor nephrectomy during January 1997 to May 1998 served as the control group. A composite cost index was constructed. LDN significantly decreased length of stay, pain, and time out of work; the supply function shifted to the right. Telephone interviews revealed that 47% donated solely because of the LDN procedure. LDN increases the supply of living donor kidneys.

  14. Immediate, short‐, and long‐term changes in tracheal stent diameter, length, and positioning after placement in dogs with tracheal collapse syndrome

    PubMed Central

    Raske, Matthew; Berent, Allyson C.; McDougall, Renee; Lamb, Kenneth

    2018-01-01

    Background Intraluminal tracheal stenting is a minimally invasive procedure shown to have variable degrees of success in managing clinical signs associated with tracheal collapse syndrome (CTCS) in dogs. Objectives Identify immediate post‐stent changes in tracheal diameter, determine the extent of stent migration, and stent shortening after stent placement in the immediate‐, short‐, and long‐term periods, and evaluate inter‐observer reliability of radiographic measurements. Animals Fifty client‐owned dogs. Methods Retrospective study in which medical records were reviewed in dogs with CTCS treated with an intraluminal tracheal stent. Data collected included signalment, location, and type of collapse, stent diameter and length, and post‐stent placement radiographic follow‐up times. Radiographs were used to obtain pre‐stent tracheal measurements and post‐stent placement measurements. Results Immediate mean percentage change was 5.14%, 5.49%, and 21.64% for cervical, thoracic inlet, and intra‐thoracic tracheal diameters, respectively. Ultimate mean follow‐up time was 446 days, with mean percentage change of 2.55%, 15.09%, and 8.65% for cervical, thoracic inlet, and intra‐thoracic tracheal diameters, respectively. Initial mean stent length was 26.72% higher than nominal length and ultimate long‐term tracheal mean stent shortening was only 9.90%. No significant stent migration was identified in the immediate, short‐, or long‐term periods. Good inter‐observer agreement of radiographic measurements was found among observers of variable experience level. Conclusions and Clinical Importance Use of an intraluminal tracheal stent for CTCS is associated with minimal stent shortening with no clinically relevant stent migration after fluoroscopic placement. Precise stent sizing and placement techniques likely play important roles in avoiding these reported complications. PMID:29460368

  15. Immediate, short-, and long-term changes in tracheal stent diameter, length, and positioning after placement in dogs with tracheal collapse syndrome.

    PubMed

    Raske, Matthew; Weisse, Chick; Berent, Allyson C; McDougall, Renee; Lamb, Kenneth

    2018-03-01

    Intraluminal tracheal stenting is a minimally invasive procedure shown to have variable degrees of success in managing clinical signs associated with tracheal collapse syndrome (CTCS) in dogs. Identify immediate post-stent changes in tracheal diameter, determine the extent of stent migration, and stent shortening after stent placement in the immediate-, short-, and long-term periods, and evaluate inter-observer reliability of radiographic measurements. Fifty client-owned dogs. Retrospective study in which medical records were reviewed in dogs with CTCS treated with an intraluminal tracheal stent. Data collected included signalment, location, and type of collapse, stent diameter and length, and post-stent placement radiographic follow-up times. Radiographs were used to obtain pre-stent tracheal measurements and post-stent placement measurements. Immediate mean percentage change was 5.14%, 5.49%, and 21.64% for cervical, thoracic inlet, and intra-thoracic tracheal diameters, respectively. Ultimate mean follow-up time was 446 days, with mean percentage change of 2.55%, 15.09%, and 8.65% for cervical, thoracic inlet, and intra-thoracic tracheal diameters, respectively. Initial mean stent length was 26.72% higher than nominal length and ultimate long-term tracheal mean stent shortening was only 9.90%. No significant stent migration was identified in the immediate, short-, or long-term periods. Good inter-observer agreement of radiographic measurements was found among observers of variable experience level. Use of an intraluminal tracheal stent for CTCS is associated with minimal stent shortening with no clinically relevant stent migration after fluoroscopic placement. Precise stent sizing and placement techniques likely play important roles in avoiding these reported complications. Copyright © 2018 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

  16. The Asian monsoon over the past 640,000 years and ice age terminations.

    PubMed

    Cheng, Hai; Edwards, R Lawrence; Sinha, Ashish; Spötl, Christoph; Yi, Liang; Chen, Shitao; Kelly, Megan; Kathayat, Gayatri; Wang, Xianfeng; Li, Xianglei; Kong, Xinggong; Wang, Yongjin; Ning, Youfeng; Zhang, Haiwei

    2016-06-30

    Oxygen isotope records from Chinese caves characterize changes in both the Asian monsoon and global climate. Here, using our new speleothem data, we extend the Chinese record to cover the full uranium/thorium dating range, that is, the past 640,000 years. The record's length and temporal precision allow us to test the idea that insolation changes caused by the Earth's precession drove the terminations of each of the last seven ice ages as well as the millennia-long intervals of reduced monsoon rainfall associated with each of the terminations. On the basis of our record's timing, the terminations are separated by four or five precession cycles, supporting the idea that the '100,000-year' ice age cycle is an average of discrete numbers of precession cycles. Furthermore, the suborbital component of monsoon rainfall variability exhibits power in both the precession and obliquity bands, and is nearly in anti-phase with summer boreal insolation. These observations indicate that insolation, in part, sets the pace of the occurrence of millennial-scale events, including those associated with terminations and 'unfinished terminations'.

  17. Influence of Age, Maturity, and Body Size on the Spatiotemporal Determinants of Maximal Sprint Speed in Boys.

    PubMed

    Meyers, Robert W; Oliver, Jon L; Hughes, Michael G; Lloyd, Rhodri S; Cronin, John B

    2017-04-01

    Meyers, RW, Oliver, JL, Hughes, MG, Lloyd, RS, and Cronin, JB. Influence of age, maturity, and body size on the spatiotemporal determinants of maximal sprint speed in boys. J Strength Cond Res 31(4): 1009-1016, 2017-The aim of this study was to investigate the influence of age, maturity, and body size on the spatiotemporal determinants of maximal sprint speed in boys. Three-hundred and seventy-five boys (age: 13.0 ± 1.3 years) completed a 30-m sprint test, during which maximal speed, step length, step frequency, contact time, and flight time were recorded using an optical measurement system. Body mass, height, leg length, and a maturity offset represented somatic variables. Step frequency accounted for the highest proportion of variance in speed (∼58%) in the pre-peak height velocity (pre-PHV) group, whereas step length explained the majority of the variance in speed (∼54%) in the post-PHV group. In the pre-PHV group, mass was negatively related to speed, step length, step frequency, and contact time; however, measures of stature had a positive influence on speed and step length yet a negative influence on step frequency. Speed and step length were also negatively influence by mass in the post-PHV group, whereas leg length continued to positively influence step length. The results highlighted that pre-PHV boys may be deemed step frequency reliant, whereas those post-PHV boys may be marginally step length reliant. Furthermore, the negative influence of body mass, both pre-PHV and post-PHV, suggests that training to optimize sprint performance in youth should include methods such as plyometric and strength training, where a high neuromuscular focus and the development force production relative to body weight are key foci.

  18. Variable length adjacent partitioning for PTS based PAPR reduction of OFDM signal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ibraheem, Zeyid T.; Rahman, Md. Mijanur; Yaakob, S. N.

    2015-05-15

    Peak-to-Average power ratio (PAPR) is a major drawback in OFDM communication. It leads the power amplifier into nonlinear region operation resulting into loss of data integrity. As such, there is a strong motivation to find techniques to reduce PAPR. Partial Transmit Sequence (PTS) is an attractive scheme for this purpose. Judicious partitioning the OFDM data frame into disjoint subsets is a pivotal component of any PTS scheme. Out of the existing partitioning techniques, adjacent partitioning is characterized by an attractive trade-off between cost and performance. With an aim of determining effects of length variability of adjacent partitions, we performed anmore » investigation into the performances of a variable length adjacent partitioning (VL-AP) and fixed length adjacent partitioning in comparison with other partitioning schemes such as pseudorandom partitioning. Simulation results with different modulation and partitioning scenarios showed that fixed length adjacent partition had better performance compared to variable length adjacent partitioning. As expected, simulation results showed a slightly better performance of pseudorandom partitioning technique compared to fixed and variable adjacent partitioning schemes. However, as the pseudorandom technique incurs high computational complexities, adjacent partitioning schemes were still seen as favorable candidates for PAPR reduction.« less

  19. Did Antarctic Intermediate Water in the Southeast Pacific expanded vertically or only deepened?

    NASA Astrophysics Data System (ADS)

    Martinez-Mendez, G.; Lamy, F.; Mohtadi, M.; Hebbeln, D.

    2017-12-01

    Paleoceanographic and modelling studies have demonstrated in the last few years that deep waters are not the single protagonists in the global circulation scheme. Intermediate waters also play various and important roles. Particularly, the Antarctic Intermediate Water (AAIW) is key for the ventilation of mid-depths and thermocline levels, with its influence being noticeable till the eastern equatorial Pacific; it is involved in rapid reorganizations of the Global Circulation and also, most plausibly, in trapping and releasing atmospheric CO2 on glacial-interglacial time scales. In recent years, several records about the past variability of the AAIW have been published while they all lay at the lower edges of the influence of this water mass and, hence, mostly only conclusions about the AAIW variability at its deep boundary could be drawn. Here we present a novel record covering several glacial-interglacial cycles from the upper levels of this water mass. Site GeoB15020 was drilled with the MARUM Sea floor drill rig (MeBo) off Chile (27.29°S; 71.05°W) at 550 m water depth (core length: 78 meters composite depth). We will present δ18O, δ13C downcore records and Mg/Ca-derived ambient temperature from peak interglacial and peak glacial periods. The records will be compared with published results from Site GeoB15016 (Martínez-Méndez et al., 2013), which lays at nearly the same position but at 956 m water depth, i.e. both cores bound the main tongue of AAIW today. The results of GeoB15016 had shown increase presence of the AAIW at the site, but it was not possible to relate unequivocally this increased presence to a deepening of the core of the AAIW or to an increase in production. Results from GeoB15020 will allow answering that dichotomy. In addition, actual changes in the intrinsic characteristics of the AAIW are poorly constrained. Therefore, we will additionally present high resolution (multi-decadal time scales) δ18O, δ13C and Sortable Silt records from core GeoB3359-3 (35.23°S; 72.81°W, 678 m, 380 cm core length) to investigate fluctuations within the core of AAIW from the Last Glacial Maximum to the present and relate those to the changes observed downstream.

  20. Efficient analysis of complex natural materials using LA-ICP-MS

    NASA Astrophysics Data System (ADS)

    Kent, A. J.; Loewen, M. W.; Koleszar, A. M.; Miller, J.; Ungerer, C. "

    2011-12-01

    Many natural materials exhibit complex variations in chemical or isotopic composition over relatively short length scales, and these compositional variations often record important information about the environment or nature of the processes that lead to formation. Examples include complexly zoned crystals within volcanic rocks that record magmatic and volcanic signals, otoliths and other biominerals that record life history and environmental information, and speleothems that record climatic variables. Laser ablation ICP-MS analyses offer several advantages for quantifying compositional in chemically complex natural materials. These include the speed of analysis, the ability to sample at atmospheric pressures, the wide diversity of possible analytes, and the ability to make measurements in both spot and raster modes. The latter in particular offers advantages for analyses that require efficient acquisition of information over significant length scales, as in raster mode compositional data can be rapidly obtained by translating the laser laterally over a compositional variable material during a single analysis. In this fashion elemental or isotopic composition at a given analysis time corresponds to the lateral spatial dimension. This contrasts with a record obtained by a row of individual spots, which require a large number of discrete analyses, and requires significantly more analysis time. However there are also disadvantages to this style of analysis. Translation of the circular spots typically used for analysis results in significant signal attenuation and production of artifacts that may mirror natural diffusion profiles or other gradual changes. The ability to ablate using non-circular spots significantly reduces this effect, although the degree of attenuation is also increased by slower ablation cell response times. For single volume cells this may result in 50-100% additional attenuation than that produced by the translation of the spot alone, although two-volume and other rapid response cells significantly reduce this effect. Raster analyses are also highly sensitive to the presence of small contaminant phases along the raster trajectory, as the compositional signal from these can become attenuated and difficult to distinguish from natural compositional variations. It can also be difficult to establish exactly where compositional changes occur in materials that are visually homogenous. In this contribution we discuss these issues in more detail and present data acquisition and processing strategies that minimize these difficulties.

  1. Prevalence, distribution, and progression of radiographic abnormalities in the lungs of cold-stunned Kemp's ridley sea turtles (Lepidochelys kempii): 89 cases (2002-2005).

    PubMed

    Stockman, Jonathan; Innis, Charles J; Solano, Mauricio; O'Sullivan Brisson, Jennifer; Kass, Philip H; Tlusty, Michael F; Weber, E Scott

    2013-03-01

    To evaluate the prevalence, distribution, and progression of radiographic abnormalities in the lungs of cold-stunned Kemp's ridley sea turtles (Lepidochelys kempii) and associations between these abnormalities and body weight, carapace length, and hematologic and plasma biochemical variables. Retrospective case series. 89 cold-stunned juvenile Kemp's ridley sea turtles. Medical records were reviewed. Dorsoventral and horizontal beam craniocaudal radiographs were evaluated for the presence, distribution, and progression of lung abnormalities. Turtles were categorized as having radiographically normal or abnormal lungs; those with abnormalities detected were further categorized according to the distribution of abnormalities (left lung, right lung, or both affected). Body weight, carapace length, and hematologic and plasma biochemical data were compared among categories. 48 of 89 (54%) turtles had radiographic abnormalities of the lungs. Unilateral abnormalities of the right or left lung were detected in 14 (16%) and 2 (2%), respectively; both lungs were affected in 32 (36%). Prevalence of unilateral abnormalities was significantly greater for the right lung than for the left lung. Evaluation of follow-up radiographs indicated clinical improvement over time for most (18/31 [58%]) turtles. Prevalence of bilateral radiographic abnormalities was positively correlated with body weight and carapace length. There was no significant association between radiographic category and hematologic or plasma biochemical variables. Radiographic abnormalities of the lungs were commonly detected in cold-stunned Kemp's ridley turtles. Results of this study may aid clinicians in developing effective diagnostic and treatment plans for these patients.

  2. On the spectral characteristics of the Atlantic multidecadal variability in an ensemble of multi-century simulations

    NASA Astrophysics Data System (ADS)

    Mavilia, Irene; Bellucci, Alessio; J. Athanasiadis, Panos; Gualdi, Silvio; Msadek, Rym; Ruprich-Robert, Yohan

    2018-01-01

    The Atlantic multidecadal variability (AMV) is a coherent pattern of variability of the North Atlantic sea surface temperature field affecting several components of the climate system in the Atlantic region and the surrounding areas. The relatively short observational record severely limits our understanding of the physical mechanisms leading to the AMV. The present study shows that the spatial and temporal characteristics of the AMV, as assessed from the historical records, should also be considered as highly uncertain. Using 11 multi-century preindustrial climate simulations from the Coupled Model Intercomparison Project Phase 5 (CMIP5) database, we show that the AMV characteristics are not constant along the simulation when assessed from different 200-year-long periods to match the observed period length. An objective method is proposed to test whether the variations of the AMV characteristics are consistent with stochastic internal variability. For 7 out of the 11 models analysed, the results indicate a non-stationary behaviour for the AMV time series. However, the possibility that the non-stationarity arises from sampling errors can be excluded with high confidence only for one of the 7 models. Therefore, longer time series are needed to robustly assess the AMV characteristics. In addition to any changes imposed to the AMV by external forcings, the detected dependence on the time interval identified in most models suggests that the character of the observed AMV may undergo significant changes in the future.

  3. Nine Hundred Years of Weekly Streamflows: Stochastic Downscaling of Ensemble Tree-Ring Reconstructions

    NASA Astrophysics Data System (ADS)

    Sauchyn, David; Ilich, Nesa

    2017-11-01

    We combined the methods and advantages of stochastic hydrology and paleohydrology to estimate 900 years of weekly flows for the North and South Saskatchewan Rivers at Edmonton and Medicine Hat, Alberta, respectively. Regression models of water-year streamflow were constructed using historical naturalized flow data and a pool of 196 tree-ring (earlywood, latewood, and annual) ring-width chronologies from 76 sites. The tree-ring models accounted for up to 80% of the interannual variability in historical naturalized flows. We developed a new algorithm for generating stochastic time series of weekly flows constrained by the statistical properties of both the historical record and proxy streamflow data, and by the necessary condition that weekly flows correlate between the end of a year and the start of the next. A second innovation, enabled by the density of our tree-ring network, is to derive the paleohydrology from an ensemble of 100 statistically significant reconstructions at each gauge. Using paleoclimatic data to generate long series of weekly flow estimates augments the short historical record with an expanded range of hydrologic variability, including sequences of wet and dry years of greater length and severity. This unique hydrometric time series will enable evaluation of the reliability of current water supply and management systems given the range of hydroclimatic variability and extremes contained in the stochastic paleohydrology. It also could inform evaluation of the uncertainty in climate model projections, given that internal hydroclimatic variability is the dominant source of uncertainty.

  4. Gait variability in community dwelling adults with Alzheimer disease.

    PubMed

    Webster, Kate E; Merory, John R; Wittwer, Joanne E

    2006-01-01

    Studies have shown that measures of gait variability are associated with falling in older adults. However, few studies have measured gait variability in people with Alzheimer disease, despite the high incidence of falls in Alzheimer disease. The purpose of this study was to compare gait variability of community-dwelling older adults with Alzheimer disease and control subjects at various walking speeds. Ten subjects with mild-moderate Alzheimer disease and ten matched control subjects underwent gait analysis using an electronic walkway. Participants were required to walk at self-selected slow, preferred, and fast speeds. Stride length and step width variability were determined using the coefficient of variation. Results showed that stride length variability was significantly greater in the Alzheimer disease group compared with the control group at all speeds. In both groups, increases in walking speed were significantly correlated with decreases in stride length variability. Step width variability was significantly reduced in the Alzheimer disease group compared with the control group at slow speed only. In conclusion, there is an increase in stride length variability in Alzheimer disease at all walking speeds that may contribute to the increased incidence of falls in Alzheimer disease.

  5. Length of service and commitment of nurses in hospitalsof Social Security Organization (SSO) in Tehran

    PubMed Central

    Jafari Kelarijani, Seyed Ebrahim; Heidarian, Ali Reza; Jamshidi, Reza; Khorshidi, Mohamad

    2014-01-01

    Background: A nurse’s commitment is the most important factor that influences her performance and depends on other variables. The purpose of this research was to study the relationship between length of service of the nurses with the amount of occupational commitment and organizational commitment. Methods: From Winter 2012 to Spring 2013, 266 nurses were chosen in selected hospitals of Social Security Organization (SSO). These nurses were randomly categorized into six different classes of service records including < 5, 5-9, 10-14, 15-19, 20-24, and 25-29 years. The length of service is related to the organizational, occupational, affective, continuance, and normative commitment. The data were collected and analyzed. Results: Generally 84% of the responders were women and the rest were men of which 95% had a bachelor’s degree and the rest had higher academic degrees. The length of service in 81% of nurses was <15 years and 19% were higher than 15 years. Significant correlation were seen between continuance and occupational commitments and length of service (r=0.23, P=0.04 and r=-0.26, P=0.02, respectively). There were not any significant differences regarding organizational, affective and normative commitments (P=0.12, P=0.33, P=0.47, respectively). Conclusion: The results show that the length of service was related to continuance and occupational commitment. So pre-retirement of the nurses after 20 years of work can result in an increase in average commitment of employees. PMID:24778784

  6. Spatiotemporal Variables of Able-bodied and Amputee Sprinters in Men's 100-m Sprint.

    PubMed

    Hobara, H; Kobayashi, Y; Mochimaru, M

    2015-06-01

    The difference in world records set by able-bodied sprinters and amputee sprinters in the men's 100-m sprint is still approximately 1 s (as of 28 March 2014). Theoretically, forward velocity in a 100-m sprint is the product of step frequency and step length. The goal of this study was to examine the hypothesis that differences in the sprint performance of able-bodied and amputee sprinters would be due to a shorter step length rather than lower step frequency. Men's elite-level 100-m races with a total of 36 able-bodied, 25 unilateral and 17 bilateral amputee sprinters were analyzed from the publicly available internet broadcasts of 11 races. For each run of each sprinter, the average forward velocity, step frequency and step length over the whole 100-m distance were analyzed. The average forward velocity of able-bodied sprinters was faster than that of the other 2 groups, but there was no significant difference in average step frequency among the 3 groups. However, the average step length of able-bodied sprinters was significantly longer than that of the other 2 groups. These results suggest that the differences in sprint performance between 2 groups would be due to a shorter step length rather than lower step frequency. © Georg Thieme Verlag KG Stuttgart · New York.

  7. Stochastic Modeling based on Dictionary Approach for the Generation of Daily Precipitation Occurrences

    NASA Astrophysics Data System (ADS)

    Panu, U. S.; Ng, W.; Rasmussen, P. F.

    2009-12-01

    The modeling of weather states (i.e., precipitation occurrences) is critical when the historical data are not long enough for the desired analysis. Stochastic models (e.g., Markov Chain and Alternating Renewal Process (ARP)) of the precipitation occurrence processes generally assume the existence of short-term temporal-dependency between the neighboring states while implying the existence of long-term independency (randomness) of states in precipitation records. Existing temporal-dependent models for the generation of precipitation occurrences are restricted either by the fixed-length memory (e.g., the order of a Markov chain model), or by the reining states in segments (e.g., persistency of homogenous states within dry/wet-spell lengths of an ARP). The modeling of variable segment lengths and states could be an arduous task and a flexible modeling approach is required for the preservation of various segmented patterns of precipitation data series. An innovative Dictionary approach has been developed in the field of genome pattern recognition for the identification of frequently occurring genome segments in DNA sequences. The genome segments delineate the biologically meaningful ``words" (i.e., segments with a specific patterns in a series of discrete states) that can be jointly modeled with variable lengths and states. A meaningful “word”, in hydrology, can be referred to a segment of precipitation occurrence comprising of wet or dry states. Such flexibility would provide a unique advantage over the traditional stochastic models for the generation of precipitation occurrences. Three stochastic models, namely, the alternating renewal process using Geometric distribution, the second-order Markov chain model, and the Dictionary approach have been assessed to evaluate their efficacy for the generation of daily precipitation sequences. Comparisons involved three guiding principles namely (i) the ability of models to preserve the short-term temporal-dependency in data through the concepts of autocorrelation, average mutual information, and Hurst exponent, (ii) the ability of models to preserve the persistency within the homogenous dry/wet weather states through analysis of dry/wet-spell lengths between the observed and generated data, and (iii) the ability to assesses the goodness-of-fit of models through the likelihood estimates (i.e., AIC and BIC). Past 30 years of observed daily precipitation records from 10 Canadian meteorological stations were utilized for comparative analyses of the three models. In general, the Markov chain model performed well. The remainders of the models were found to be competitive from one another depending upon the scope and purpose of the comparison. Although the Markov chain model has a certain advantage in the generation of daily precipitation occurrences, the structural flexibility offered by the Dictionary approach in modeling the varied segment lengths of heterogeneous weather states provides a distinct and powerful advantage in the generation of precipitation sequences.

  8. Normative data for uterine size according to age and gravidity and possible role of the classical golden ratio.

    PubMed

    Verguts, J; Ameye, L; Bourne, T; Timmerman, D

    2013-12-01

    To document normal measurements (length, width, anteroposterior (AP) diameter) and proportions of the non-pregnant uterus according to age and gravidity. We hypothesized that uterine proportions conform to the classical 'golden ratio' (1.618). This was a retrospective study of ultrasonographic measurements of the length, width and AP diameter of non-pregnant uteri recorded in our database between 1 January 2000 and 31 July 2012. All patients for whom abnormal findings were reported were excluded and only the first set of measurements for each patient was retained for analysis. Loess (local regression) analysis was performed using age and gravidity as explanatory variables. Measurements of 5466 non-pregnant uteri were retrieved for analysis. The mean length was found to increase to 72 mm at the age of 40 and decrease to 42 mm at the age of 80 years. Gravidity was associated with greater uterine length, width and AP diameter. Mean length/width ratio was found to be 1.857 at birth, decreasing to 1.452 at the age of 91 years. At the age of 21 years, the mean ratio was found to be 1.618, i.e. equal to the golden ratio. Increasing gravidity was associated with lower mean length/width ratio. Uterine size in non-pregnant women varies in relation to age and gravidity. Mean length/width ratio conformed to the golden ratio at the age of 21, coinciding with peak fertility. Copyright © 2013 ISUOG. Published by John Wiley & Sons Ltd.

  9. Head circumference, leg length and its association with dementia among older adult population in Singapore.

    PubMed

    Chang, Sherilyn; Ong, Hui Lin; Abdin, Edimansyah; Vaingankar, Janhavi Ajit; Jeyagurunathan, Anitha; Shafie, Saleha; Mahendran, Rathi; Subramaniam, Mythily; Chong, Siow Ann

    2017-12-01

    Head circumference and leg length serve as reliable proxy indicators of early-life environment. Research studies have shown that these anthropometric measurements are associated with cognitive impairment and dementia among older adults. The aim of the present study was to assess the associations between dementia with head circumference and leg length among the older adult population in Singapore. This study also aimed to examine the sociodemographic correlates of these anthropometric measurements. Data were collected from 2565 older adults aged 60 years and above, in a population study on the Well-being of the Singapore Elderly. Head circumference and leg length measurements were obtained, and sociodemographic information was recorded. Dementia diagnosis was made using the 10/66 dementia algorithm. Anthropometric measurements were first stratified into quarters, and then logistic regression analysis was used to examine factors associated with head circumference and leg length, as well as to examine the association between dementia with these measurements. Sociodemographic correlates of head circumference and leg length include age, gender, ethnicity and education level. Smaller head circumference was independently associated with higher odds of 10/66 dementia (OR = 2.173-2.709). When the regression analysis was stratified by gender, the association was found only in the male sample. Leg length was not significantly associated with dementia after controlling for sociodemographic variables. Smaller head circumference is independently associated with dementia among older adults in Singapore. Findings from this study suggest that risk factors for dementia begin their influence in early life. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  10. Annually resolved North Atlantic marine climate over the last millennium

    NASA Astrophysics Data System (ADS)

    Reynolds, D. J.; Scourse, J. D.; Halloran, P. R.; Nederbragt, A. J.; Wanamaker, A. D.; Butler, P. G.; Richardson, C. A.; Heinemeier, J.; Eiríksson, J.; Knudsen, K. L.; Hall, I. R.

    2016-12-01

    Owing to the lack of absolutely dated oceanographic information before the modern instrumental period, there is currently significant debate as to the role played by North Atlantic Ocean dynamics in previous climate transitions (for example, Medieval Climate Anomaly-Little Ice Age, MCA-LIA). Here we present analyses of a millennial-length, annually resolved and absolutely dated marine δ18O archive. We interpret our record of oxygen isotope ratios from the shells of the long-lived marine bivalve Arctica islandica (δ18O-shell), from the North Icelandic shelf, in relation to seawater density variability and demonstrate that solar and volcanic forcing coupled with ocean circulation dynamics are key drivers of climate variability over the last millennium. During the pre-industrial period (AD 1000-1800) variability in the sub-polar North Atlantic leads changes in Northern Hemisphere surface air temperatures at multi-decadal timescales, indicating that North Atlantic Ocean dynamics played an active role in modulating the response of the atmosphere to solar and volcanic forcing.

  11. Profile of children and adolescents admitted to a Burn Care Unit in the countryside of the state of São Paulo☆

    PubMed Central

    Biscegli, Terezinha Soares; Benati, Larissa Delázari; Faria, Rafaela Sperandio; Boeira, Taís Romano; Cid, Felipe Biscegli; Gonsaga, Ricardo Alessandro Teixeira

    2014-01-01

    Objective: To describe the profile of pediatric burn victims hospitalized at Hospital-Escola Padre Albino (HEPA), in Catanduva, São Paulo, Brazil. Methods: This was a cross-sectional, retrospective study analyzing 446 medical records of patient aged 0-18 years old hospitalized in the Burn Care Unit of HEPA, from 2002 to 2012. The following variables were recorded: demographic data, skin burn causes, lesions characteristics, complications, surgical procedures, length of hospital stay, and outcome. Descriptive statistics were used. Results: 382 patients with full medical records were included in the study. Burns were more frequent in males (64.4%) and in children aged less than 6 years (52.9%). Most accidents occurred at home (67.3%) and hot liquids were responsible for 47.1% of them. Mean burnt body surface was 18% and the most affected body areas were chest and limbs. First- and second-degree burns were observed in 64.4% of the cases. Secondary infection and surgical procedures occurred in 6.5% and 45.0% of the patients, respectively. Mean length of hospital stay was 9.8 days. The mortality rate was 1.6%. Conclusions: Preschool children were the main victims of burns occurring at home, representing the largest contingent of hospitalizations due to this cause in individuals aged < 18 years. It is important to develop strategies to alert parents and general society through educational programs and preventive campaigns. PMID:25479846

  12. Night-time activity forecast by season and weather in a longitudinal design - natural light effects on three years' rest-activity cycles in nursing home residents with dementia.

    PubMed

    Wahnschaffe, Amely; Nowozin, Claudia; Rath, Andreas; Floessner, Theresa; Appelhoff, Stefan; Münch, Mirjam; Kunz, Dieter

    2017-12-01

    Backround: Night-time agitation is a frequent symptom of dementia. It often causes nursing home admission and has been linked to circadian rhythm disturbances. A positive influence of light interventions on night-time agitation was shown in several studies. The aim of our study was to investigate whether there is a long-term association between regional weather data (as indicator for daylight availability) and 24-hour variations of motor activity. Motor activity of 20 elderly nursing home residents living with dementia was analyzed using recordings of continuously worn wrist activity monitors over a three-year period. The average recording duration was 479 ± 206 days per participant (mean ± SD). Regional cloud amount and day length data from the local weather station (latitude: 52°56'N) were included in the analysis to investigate their effects on several activity variables. Nocturnal rest, here defined as the five consecutive hours with the least motor activity during 24 hours (L5), was the most predictable activity variable per participant. There was a significant interaction of night-time activity with day length and cloud amount (F 1,1174 = 4.39; p = 0.036). Night-time activity was higher on cloudy short days than on clear short days (p = 0.007), and it was also higher on cloudy short days than on cloudy long days (p = 0.032). The need for sufficient zeitgeber (time cue) strength during winter time, especially when days are short and skies are cloudy, is crucial for elderly people living with dementia. Activity forecast by season and weather might be a valuable approach to anticipate adequately complementary use of electrical light and thereby foster lower night-time activity.

  13. Seasonal to interannual morphodynamics along a high-energy dissipative littoral cell

    USGS Publications Warehouse

    Ruggiero, P.; Kaminsky, G.M.; Gelfenbaum, G.; Voigt, B.

    2005-01-01

    A beach morphology monitoring program was initiated during summer 1997 along the Columbia River littoral cell (CRLC) on the coasts of northwest Oregon and southwest Washington, USA. This field program documents the seasonal through interannual morphological variability of these high-energy dissipative beaches over a variety of spatial scales. Following the installation of a dense network of geodetic control monuments, a nested sampling scheme consisting of cross-shore topographic beach profiles, three-dimensional topographic beach surface maps, nearshore bathymetric surveys, and sediment size distribution analyses was initiated. Beach monitoring is being conducted with state-of-the-art real-time kinematic differential global positioning system survey methods that combine both high accuracy and speed of measurement. Sampling methods resolve variability in beach morphology at alongshore length scales of approximately 10 meters to approximately 100 kilometers and cross-shore length scales of approximately 1 meter to approximately 2 kilometers. During the winter of 1997/1998, coastal change in the US Pacific Northwest was greatly influenced by one of the strongest El Nin??o events on record. Steeper than typical southerly wave angles resulted in alongshore sediment transport gradients and shoreline reorientation on a regional scale. The La Nin??a of 1998/1999, dominated by cross-shore processes associated with the largest recorded wave year in the region, resulted in net beach erosion along much of the littoral cell. The monitoring program successfully documented the morphological response to these interannual forcing anomalies as well as the subsequent beach recovery associated with three consecutive moderate wave years. These morphological observations within the CRLC can be generalized to explain overall system patterns; however, distinct differences in large-scale coastal behavior (e.g., foredune ridge morphology, sandbar morphometrics, and nearshore beach slopes) are not readily explained or understood.

  14. Thirty-five-year climatic cycle in heliogeophysics, psychophysiology, military politics, and economics

    NASA Astrophysics Data System (ADS)

    Halberg, F.; Cornélissen, G.; Sothern, R. B.; Czaplicki, J.; Schwartzkopff, O.

    2010-12-01

    Cycles of about 35 years found in the climate by Brückner and Egeson were aligned with periodic changes in the length of the solar cycle by the Lockyers. The solar-cycle length and climate were subsequently revisited without reference to any cyclicity or those who discovered it. The descriptive statistics of Bruckner and Lockyer were repeatedly questioned and, with notable exceptions, have been forgotten. Bruckner's data, taken from his summary chart, are shown here for the first time inferentially statistically validated as nonstationary (to the point of intermittency) and, as transdisciplinary, extending from meteorology to 2556 years of international battles; to 2189 years of tree rings; to ˜900 years of northern lights; to 400 years of economics; to 173 years of military affairs; and to ˜40 years of helio-, interplanetary- and geomagnetics matching a longitudinal record by a healthy individual who self-measured his heart rate and mental functions (with a 1-min time estimation), among other variables. Space weather, mirrored in the circulation of human blood, can be tracked biologically as a dividend from self-assessed preventive health care including the automatically and ambulatory-recorded heart rate and blood pressure for detecting and treating heretofore ignored vascular variability disorders. A website providing free analyses for anyone (in exchange for their data) could serve any community with computer-savvy members and could start focusing the attention of the population at large on problems of societal as well as individual health. Space weather was found to affect the human cardiovascular system, and it has been supposed that data on space weather can be inversely assimilated from biological self-monitoring data.

  15. Duration of hospital stay following orthognathic surgery at the jordan university hospital.

    PubMed

    Jarab, Fadi; Omar, Esam; Bhayat, Ahmed; Mansuri, Samir; Ahmed, Sami

    2012-09-01

    Major oral and maxillofacial surgery procedures have been routinely performed on an inpatient basis in order to manage both, the recovery from anesthesia and any unpredictable morbidity that may be associated with the surgery. The use of inpatient beds is extremely expensive and if the surgical procedures could be done on an outpatient setting, it would reduce the costs and the need for inpatient care. The aim was to determine the length of hospital stay (LHS) and the factors which influence the LHS following orthognathic surgery at the Jordan University Hospital over 5 years (2005-2009). This was a retrospective record review of patients who underwent orthognathic surgery at Jordan University Hospital between 2005 and 2009. The variables were recorded on a data capture form which was adapted and developed from previous studies. Descriptive and analytical statistical methods were used to correlate these variables to the LHS. Ninety two patients were included in the study and 74% of them were females. The mean age was 23.7 years and the mean LHS was 4 days. The complexity of the procedure, length of operation time, intensive care unit (ICU) stay and year of operation were significantly correlated with a positive LHS (P < 0.05). Patients' hospital stay was directly related to the complexity of the orthognathic procedure, the operation time, time spent in ICU and the year in which the operation was done. There was a significant reduction in the LHS over the progressing years and this could be due to an increase in experience and knowledge of the operators and an improvement in the hospital facilities.

  16. Comparison of a clinical gait analysis method using videography and temporal-distance measures with 16-mm cinematography.

    PubMed

    Stuberg, W A; Colerick, V L; Blanke, D J; Bruce, W

    1988-08-01

    The purpose of this study was to compare a clinical gait analysis method using videography and temporal-distance measures with 16-mm cinematography in a gait analysis laboratory. Ten children with a diagnosis of cerebral palsy (means age = 8.8 +/- 2.7 years) and 9 healthy children (means age = 8.9 +/- 2.4 years) participated in the study. Stride length, walking velocity, and goniometric measurements of the hip, knee, and ankle were recorded using the two gait analysis methods. A multivariate analysis of variance was used to determine significant differences between the data collected using the two methods. Pearson product-moment correlation coefficients were determined to examine the relationship between the measurements recorded by the two methods. The consistency of performance of the subjects during walking was examined by intraclass correlation coefficients. No significant differences were found between the methods for the variables studied. Pearson product-moment correlation coefficients ranged from .79 to .95, and intraclass coefficients ranged from .89 to .97. The clinical gait analysis method was found to be a valid tool in comparison with 16-mm cinematography for the variables that were studied.

  17. Determinants of Major League Baseball Pitchers' Career Length.

    PubMed

    Hardy, Rich; Ajibewa, Tiwaloluwa; Bowman, Ray; Brand, Jefferson C

    2017-02-01

    To investigate variables (injury, position, performance, and pitching volume) that affect the career longevity of Major League Baseball pitchers. To be eligible, pitchers must have entered Major League Baseball between 1989 and 1992 without missing information for the variables on the website http://www.baseball-reference.com. The variables assessed were average innings pitched per year before and after age 25 years, earned run average, walks and hits divided by innings pitched, strikeout to walk ratio, pitching position, time on the disabled list, length of career, and starting and retirement age. We used analysis of variance to compare the differences between groups and a regression model to assess the relationship between variables before age 25 years and career length. Mean retirement age for the group was 31.74 (95% confidence interval 30.83-32.65) and mean career length was 10.97 (95% confidence interval, 10.02-11.92) years. Innings pitched after age 25 years increased slightly, but not significantly, from the number of innings pitched before age 25 years, 85.35 versus 74.25, P = .5063. Career earned run average was not significantly different after age 25 years compared with before age 25 years, 4.83 versus 5.58, respectively, P = .8834. Both strikeout to walk ratio, 1.55 to 1.77, P = .0022, and walks and hits divided by innings pitched, 1.63 to 1.50, P = .0339, improved significantly after age 25 years compared with before age 25 years. The position the player started and ended his career (starter or reliever) did not influence career length. Multiple regression analysis comparing the variables from before age 25 revealed only the number of innings pitched before age 25 were positively related to career length, R 2  = 0.1408, P < .0001. All other variables analyzed before age 25 years were not significantly related to career length. The only studied variable that had significant relationship, which was weak to low, with career length was innings pitched per year before age 25 years. All other variables analyzed before age 25 years were not significantly related to career length. Level IV, case series. Copyright © 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  18. The Influence of Item Calibration Error on Variable-Length Computerized Adaptive Testing

    ERIC Educational Resources Information Center

    Patton, Jeffrey M.; Cheng, Ying; Yuan, Ke-Hai; Diao, Qi

    2013-01-01

    Variable-length computerized adaptive testing (VL-CAT) allows both items and test length to be "tailored" to examinees, thereby achieving the measurement goal (e.g., scoring precision or classification) with as few items as possible. Several popular test termination rules depend on the standard error of the ability estimate, which in turn depends…

  19. Development of the Wintertime Sr/Ca-SST Record from Red Sea Corals as a Proxy for the North Atlantic Oscillation

    NASA Astrophysics Data System (ADS)

    Bernstein, W. N.; Hughen, K. A.

    2009-12-01

    The North Atlantic Oscillation (NAO) is one of the most pronounced and influential patterns in winter atmospheric circulation variability. This meridional redistribution of atmospheric mass across the Atlantic Ocean produces large changes in the intensity, number and direction of storms generated within the basin, and the regional climate of surrounding continents. The NAO exerts a significant impact on society, through influences on agriculture, fisheries, water management, energy generation and coastal development. NAO effects on climate extend from eastern North America across Europe to the eastern Mediterranean and Middle East. Changes in NAO behavior during the late 20th century have been linked to global warming; yet despite its importance, the causes and long-term patterns of NAO variability in the past remain poorly understood. In order to better predict the influence of the NAO on climate in the future, it is critical to examine multi-century NAO variability. The Red Sea is an excellent location from which to generate long NAO records for two reasons. First, patterns of wintertime sea surface temperature (SST) and salinity (SSS) in the Red Sea are highly correlated with NAO variability (Visbeck et al. 2001; Hurrell et al. 2003). Second, the tropical/subtropical Red Sea region contains fast growing long-lived massive Porites spp. corals with annually banded skeletons. These corals are ideal for generating well-dated high-resolution paleoclimatic records that extend well beyond the instrumental period. Here we present a study of winter SST and NAO variability in the Red sea region based on coral Sr/Ca data. In 2008, we collected multiple drill cores ranging in length from 1 to 4.1 meters from Porites corals at six sites spanning a large SST gradient. Sr/Ca measurements from multiple corals will be regressed against 23 years of satellite SST data, expanding the SST range over which we calibrate. A sampling resolution of 0.5mm will yield greater than bi-weekly temporal resolution for downcore SST reconstructions over the past 140 years, which will be used to evaluate the ability of the coral proxies to capture instrumental NAO variability. We expect that this winter Sr/Ca record will exhibit coherence with the NAO similar to that evident between Red Sea instrumental SST and the NAO index. Future work will involve construction of an NAO record back ~400 years, using the multi-core Sr/Ca-SST calibration applied to a combination of new records from modern and fossil coral material. This record will be examined to identify changes in NAO behavior as a function of frequency, and to compare frequency-dependent NAO variability between periods of relatively warm and cold hemispheric climate. This analysis will allow us to test the hypothesized link between NAO behavior and mean climate conditions, and if confirmed, improve predictions regarding the role of the NAO in impending climate change. References Hurrell, J. et al., 2003, in The North Atlantic Oscillation: Climatic Significance and Environmental Impact, 1-36 (A.G.U., Washington, D.C.). Visbeck, M. et al., 2001, Proc. Nat. Acad. Sci. 98, 12876-12877.

  20. Weights and measures: a new look at bisection behaviour in neglect.

    PubMed

    McIntosh, Robert D; Schindler, Igor; Birchall, Daniel; Milner, A David

    2005-12-01

    Horizontal line bisection is a ubiquitous task in the investigation of visual neglect. Patients with left neglect typically make rightward errors that increase with line length and for lines at more leftward positions. For short lines, or for lines presented in right space, these errors may 'cross over' to become leftward. We have taken a new approach to these phenomena by employing a different set of dependent and independent variables for their description. Rather than recording bisection error, we record the lateral position of the response within the workspace. We have studied how this varies when the locations of the left and right endpoints are manipulated independently. Across 30 patients with left neglect, we have observed a characteristic asymmetry between the 'weightings' accorded to the two endpoints, such that responses are less affected by changes in the location of the left endpoint than by changes in the location of the right. We show that a simple endpoint weightings analysis accounts readily for the effects of line length and spatial position, including cross-over effects, and leads to an index of neglect that is more sensitive than the standard measure. We argue that this novel approach is more parsimonious than the standard model and yields fresh insights into the nature of neglect impairment.

  1. Heart rate variability (HRV) and muscular system activity (EMG) in cases of crash threat during simulated driving of a passenger car.

    PubMed

    Zużewicz, Krystyna; Roman-Liu, Danuta; Konarska, Maria; Bartuzi, Paweł; Matusiak, Krzysztof; Korczak, Dariusz; Lozia, Zbigniew; Guzek, Marek

    2013-10-01

    The aim of the study was to verify whether simultaneous responses from the muscular and circulatory system occur in the driver's body under simulated conditions of a crash threat. The study was carried out in a passenger car driving simulator. The crash was included in the driving test scenario developed in an urban setting. In the group of 22 young male subjects, two physiological signals - ECG and EMG were continuously recorded. The length of the RR interval in the ECG signal was assessed. A HRV analysis was performed in the time and frequency domains for 1-minute record segments at rest (seated position), during undisturbed driving as well as during and several minutes after the crash. For the left and right side muscles: m. trapezius (TR) and m. flexor digitorum superficialis (FDS), the EMG signal amplitude was determined. The percentage of maximal voluntary contraction (MVC) was compared during driving and during the crash. As for the ECG signal, it was found that in most of the drivers changes occurred in the parameter values reflecting HRV in the time domain. Significant changes were noted in the mean length of RR intervals (mRR). As for the EMG signal, the changes in the amplitude concerned the signal recorded from the FDS muscle. The changes in ECG and EMG were simultaneous in half of the cases. Such parameters as mRR (ECG signal) and FDS-L amplitude (EMG signal) were the responses to accident risk. Under simulated conditions, responses from the circulatory and musculoskeletal systems are not always simultaneous. The results indicate that a more complete driver's response to a crash in road traffic is obtained based on parallel recording of two physiological signals (ECG and EMG).

  2. A variable mixing-length ratio for convection theory

    NASA Technical Reports Server (NTRS)

    Chan, K. L.; Wolff, C. L.; Sofia, S.

    1981-01-01

    It is argued that a natural choice for the local mixing length in the mixing-length theory of convection has a value proportional to the local density scale height of the convective bubbles. The resultant variable mixing-length ratio (the ratio between the mixing length and the pressure scale height) of this theory is enhanced in the superadiabatic region and approaches a constant in deeper layers. Numerical tests comparing the new mixing length successfully eliminate most of the density inversion that typically plagues conventional results. The new approach also seems to indicate the existence of granular motion at the top of the convection zone.

  3. Sex modifies the relationship between age and gait: a population-based study of older adults.

    PubMed

    Callisaya, Michele L; Blizzard, Leigh; Schmidt, Michael D; McGinley, Jennifer L; Srikanth, Velandai K

    2008-02-01

    Adequate mobility is essential to maintain an independent and active lifestyle. The aim of this cross-sectional study is to examine the associations of age with temporal and spatial gait variables in a population-based sample of older people, and whether these associations are modified by sex. Men and women aged 60-86 years were randomly selected from the Southern Tasmanian electoral roll (n = 223). Gait speed, step length, cadence, step width, and double-support phase were recorded with a GAITRite walkway. Regression analysis was used to model the relationship between age, sex, and gait variables. For men, after adjusting for height and weight, age was linearly associated with all gait variables (p <.05) except cadence (p =.11). For women, all variables demonstrated a curvilinear association, with age-related change in these variables commencing during the 7th decade. Significant interactions were found between age and sex for speed (p =.04), cadence (p =.01), and double-support phase (p =.03). Associations were observed between age and a broad range of temporal and spatial gait variables in this study. These associations differed by sex, suggesting that the aging process may affect gait in men and women differently. These results provide a basis for further research into sex differences and mechanisms underlying gait changes with advancing age.

  4. The fossil record of evolution: Data on diversification and extinction

    NASA Technical Reports Server (NTRS)

    Sepkoski, J. J., Jr.

    1986-01-01

    Synoptic studies of the fossil record of complex life on Earth indicate increasingly that extinction, and especially mass extinction, were extremely important driving forces in the history of life. Analysis of a new compilation of geologic ranges for 25,000 genera of marine animals suggests that extinction events were much more frequent in occurrence and variable in magnitude than previously suspected. At least 30 well documented and potential mass extinctions were identified in the dataset. The most recent event, distributed over 260 to 0 ma. exhibit a stationary periodicity of 26.1 + or - 1 ma, implicating a cosmological forcing mechanism. Earlier events, especially in the 575 to 450 ma interval, are more frequent, possibly indicating either a breakdown of periodicity in the more distant past; and as yet undemonstrated diminution of the period length; or frequent aperiodic terrestrial perturbations of a less stable biota superimposed upon the cosmological periodicity.

  5. The Effects of Respondents' Consent to Be Recorded on Interview Length and Data Quality in a National Panel Study

    ERIC Educational Resources Information Center

    McGonagle, Katherine A.; Brown, Charles; Schoeni, Robert F.

    2015-01-01

    Recording interviews is a key feature of quality control protocols for most survey organizations. We examine the effects on interview length and data quality of a new protocol adopted by a national panel study. The protocol recorded a randomly chosen one-third of all interviews digitally, although all respondents were asked for permission to…

  6. The effect of epoch length on estimated EEG functional connectivity and brain network organisation

    NASA Astrophysics Data System (ADS)

    Fraschini, Matteo; Demuru, Matteo; Crobe, Alessandra; Marrosu, Francesco; Stam, Cornelis J.; Hillebrand, Arjan

    2016-06-01

    Objective. Graph theory and network science tools have revealed fundamental mechanisms of functional brain organization in resting-state M/EEG analysis. Nevertheless, it is still not clearly understood how several methodological aspects may bias the topology of the reconstructed functional networks. In this context, the literature shows inconsistency in the chosen length of the selected epochs, impeding a meaningful comparison between results from different studies. Approach. The aim of this study was to provide a network approach insensitive to the effects that epoch length has on functional connectivity and network reconstruction. Two different measures, the phase lag index (PLI) and the amplitude envelope correlation (AEC) were applied to EEG resting-state recordings for a group of 18 healthy volunteers using non-overlapping epochs with variable length (1, 2, 4, 6, 8, 10, 12, 14 and 16 s). Weighted clustering coefficient (CCw), weighted characteristic path length (L w) and minimum spanning tree (MST) parameters were computed to evaluate the network topology. The analysis was performed on both scalp and source-space data. Main results. Results from scalp analysis show a decrease in both mean PLI and AEC values with an increase in epoch length, with a tendency to stabilize at a length of 12 s for PLI and 6 s for AEC. Moreover, CCw and L w show very similar behaviour, with metrics based on AEC more reliable in terms of stability. In general, MST parameters stabilize at short epoch lengths, particularly for MSTs based on PLI (1-6 s versus 4-8 s for AEC). At the source-level the results were even more reliable, with stability already at 1 s duration for PLI-based MSTs. Significance. The present work suggests that both PLI and AEC depend on epoch length and that this has an impact on the reconstructed network topology, particularly at the scalp-level. Source-level MST topology is less sensitive to differences in epoch length, therefore enabling the comparison of brain network topology between different studies.

  7. Great earthquakes of variable magnitude at the Cascadia subduction zone

    USGS Publications Warehouse

    Nelson, A.R.; Kelsey, H.M.; Witter, R.C.

    2006-01-01

    Comparison of histories of great earthquakes and accompanying tsunamis at eight coastal sites suggests plate-boundary ruptures of varying length, implying great earthquakes of variable magnitude at the Cascadia subduction zone. Inference of rupture length relies on degree of overlap on radiocarbon age ranges for earthquakes and tsunamis, and relative amounts of coseismic subsidence and heights of tsunamis. Written records of a tsunami in Japan provide the most conclusive evidence for rupture of much of the plate boundary during the earthquake of 26 January 1700. Cascadia stratigraphic evidence dating from about 1600??cal yr B.P., similar to that for the 1700 earthquake, implies a similarly long rupture with substantial subsidence and a high tsunami. Correlations are consistent with other long ruptures about 1350??cal yr B.P., 2500??cal yr B.P., 3400??cal yr B.P., 3800??cal yr B.P., 4400??cal yr B.P., and 4900??cal yr B.P. A rupture about 700-1100??cal yr B.P. was limited to the northern and central parts of the subduction zone, and a northern rupture about 2900??cal yr B.P. may have been similarly limited. Times of probable short ruptures in southern Cascadia include about 1100??cal yr B.P., 1700??cal yr B.P., 3200??cal yr B.P., 4200??cal yr B.P., 4600??cal yr B.P., and 4700??cal yr B.P. Rupture patterns suggest that the plate boundary in northern Cascadia usually breaks in long ruptures during the greatest earthquakes. Ruptures in southernmost Cascadia vary in length and recurrence intervals more than ruptures in northern Cascadia.

  8. Structures of the recurrence plot of heart rate variability signal as a tool for predicting the onset of paroxysmal atrial fibrillation.

    PubMed

    Mohebbi, Maryam; Ghassemian, Hassan; Asl, Babak Mohammadzadeh

    2011-05-01

    This paper aims to propose an effective paroxysmal atrial fibrillation (PAF) predictor which is based on the analysis of the heart rate variability (HRV) signal. Predicting the onset of PAF, based on non-invasive techniques, is clinically important and can be invaluable in order to avoid useless therapeutic interventions and to minimize the risks for the patients. This method consists of four steps: Preprocessing, feature extraction, feature reduction, and classification. In the first step, the QRS complexes are detected from the electrocardiogram (ECG) signal and then the HRV signal is extracted. In the next step, the recurrence plot (RP) of HRV signal is obtained and six features are extracted to characterize the basic patterns of the RP. These features consist of length of longest diagonal segments, average length of the diagonal lines, entropy, trapping time, length of longest vertical line, and recurrence trend. In the third step, these features are reduced to three features by the linear discriminant analysis (LDA) technique. Using LDA not only reduces the number of the input features, but also increases the classification accuracy by selecting the most discriminating features. Finally, a support vector machine-based classifier is used to classify the HRV signals. The performance of the proposed method in prediction of PAF episodes was evaluated using the Atrial Fibrillation Prediction Database which consists of both 30-minutes ECG recordings end just prior to the onset of PAF and segments at least 45 min distant from any PAF events. The obtained sensitivity, specificity, and positive predictivity were 96.55%, 100%, and 100%, respectively.

  9. FTIR quantification of industrial hydraulic fluids in perchloroethylene

    NASA Technical Reports Server (NTRS)

    Mehta, Narinder K.

    1993-01-01

    The purpose of this summer research project was to investigate whether perchloroethylene can be used as a solvent for the quantitative analysis of industrial hydraulic fluids by infrared spectroscopy employing Beer's law. Standard calibration curves using carbon-hydrogen stretching (generic) and ester absorption peaks were prepared for a series of standard dilutions at low ppm levels of concentration of seven hydraulic fluids in perchloroethylene. The absorbance spectras were recorded with 1.5-10 mm fixed and variable path length sample cells made of potassium bromide. The results indicate that using ester infrared spectral peak, it is possible to detect about 20 ppm of the hydraulic fluid in perchloroethylene.

  10. Some considerations in the design of transport aircraft /The W. Rupert Turnbull Lecture for 1975/

    NASA Technical Reports Server (NTRS)

    Jones, R. T.

    1975-01-01

    The slow landing speeds (30 mph, 65 mph) and light wing loading required for safety in the early days of aviation are shown to be irrelevant to safe landings of propeller-driven aircraft, while increases in wing loading and landing speed have been accompanied by improved safety records. This is attributed to length of runway and time available for approach maneuvers, plus immunity to wind gusts and turbulence conferred by higher wing loadings. Aerodynamical and mechanical aspects of safe landing are discussed, with no mention of instruments. Fuel savings achievable through high aspect ratio, variable sweep angle, and supercritical airfoils are also considered.

  11. Behavioral Dynamics in Swimming: The Appropriate Use of Inertial Measurement Units.

    PubMed

    Guignard, Brice; Rouard, Annie; Chollet, Didier; Seifert, Ludovic

    2017-01-01

    Motor control in swimming can be analyzed using low- and high-order parameters of behavior. Low-order parameters generally refer to the superficial aspects of movement (i.e., position, velocity, acceleration), whereas high-order parameters capture the dynamics of movement coordination. To assess human aquatic behavior, both types have usually been investigated with multi-camera systems, as they offer high three-dimensional spatial accuracy. Research in ecological dynamics has shown that movement system variability can be viewed as a functional property of skilled performers, helping them adapt their movements to the surrounding constraints. Yet to determine the variability of swimming behavior, a large number of stroke cycles (i.e., inter-cyclic variability) has to be analyzed, which is impossible with camera-based systems as they simply record behaviors over restricted volumes of water. Inertial measurement units (IMUs) were designed to explore the parameters and variability of coordination dynamics. These light, transportable and easy-to-use devices offer new perspectives for swimming research because they can record low- to high-order behavioral parameters over long periods. We first review how the low-order behavioral parameters (i.e., speed, stroke length, stroke rate) of human aquatic locomotion and their variability can be assessed using IMUs. We then review the way high-order parameters are assessed and the adaptive role of movement and coordination variability in swimming. We give special focus to the circumstances in which determining the variability between stroke cycles provides insight into how behavior oscillates between stable and flexible states to functionally respond to environmental and task constraints. The last section of the review is dedicated to practical recommendations for coaches on using IMUs to monitor swimming performance. We therefore highlight the need for rigor in dealing with these sensors appropriately in water. We explain the fundamental and mandatory steps to follow for accurate results with IMUs, from data acquisition (e.g., waterproofing procedures) to interpretation (e.g., drift correction).

  12. Behavioral Dynamics in Swimming: The Appropriate Use of Inertial Measurement Units

    PubMed Central

    Guignard, Brice; Rouard, Annie; Chollet, Didier; Seifert, Ludovic

    2017-01-01

    Motor control in swimming can be analyzed using low- and high-order parameters of behavior. Low-order parameters generally refer to the superficial aspects of movement (i.e., position, velocity, acceleration), whereas high-order parameters capture the dynamics of movement coordination. To assess human aquatic behavior, both types have usually been investigated with multi-camera systems, as they offer high three-dimensional spatial accuracy. Research in ecological dynamics has shown that movement system variability can be viewed as a functional property of skilled performers, helping them adapt their movements to the surrounding constraints. Yet to determine the variability of swimming behavior, a large number of stroke cycles (i.e., inter-cyclic variability) has to be analyzed, which is impossible with camera-based systems as they simply record behaviors over restricted volumes of water. Inertial measurement units (IMUs) were designed to explore the parameters and variability of coordination dynamics. These light, transportable and easy-to-use devices offer new perspectives for swimming research because they can record low- to high-order behavioral parameters over long periods. We first review how the low-order behavioral parameters (i.e., speed, stroke length, stroke rate) of human aquatic locomotion and their variability can be assessed using IMUs. We then review the way high-order parameters are assessed and the adaptive role of movement and coordination variability in swimming. We give special focus to the circumstances in which determining the variability between stroke cycles provides insight into how behavior oscillates between stable and flexible states to functionally respond to environmental and task constraints. The last section of the review is dedicated to practical recommendations for coaches on using IMUs to monitor swimming performance. We therefore highlight the need for rigor in dealing with these sensors appropriately in water. We explain the fundamental and mandatory steps to follow for accurate results with IMUs, from data acquisition (e.g., waterproofing procedures) to interpretation (e.g., drift correction). PMID:28352243

  13. Evaluation of eating and rumination behaviour in cows using a noseband pressure sensor

    PubMed Central

    2013-01-01

    Background An automated technique for recording eating and rumination behaviour was evaluated in ten lactating Brown Swiss cows by comparing data obtained from a pressure sensor with data obtained via direct observation over a 24-hour period. The recording device involved a pressure sensor integrated in the noseband of a halter. The analysed variables included number and duration of individual rumination, eating and resting phases, total daily length of these phases and number of cuds chewed per day. Results Eating and rumination phases were readily differentiated based on characteristic pressure profiles. Chewing movements during rumination were regular and generated regular waveforms with uniform amplitudes, whereas eating generated irregular waveforms with variable amplitudes. There was complete or almost complete agreement and no significant differences between data obtained via direct observation and pressure sensor technique. Both methods yielded an average of 16 daily eating phases with a mean duration of 28.3 minutes. Total time spent eating was 445.0 minutes for direct observation and 445.4 minutes for the pressure sensor technique. Both techniques recorded an average of 13.3 rumination phases with a mean duration of 30.3 (direct observation) and of 30.2 (pressure sensor) minutes. Total time spent ruminating per day, number of cuds per day and chewing cycles per cud were 389.3 and 388.3 minutes, 410.1 and 410.0 and 60.0 and 60.3 for direct observation and pressure sensor technique, respectively. There was a significant difference between the two methods with respect to mean number of chewing cycles per day (24′669, direct observation vs. 24′751, pressure sensor, P < 0.05, paired t-test). There were strong correlations between the two recording methods with correlation coefficients ranging from 0.98 to 1.00. Conclusions The results confirmed that measurements of eating and rumination variables obtained via the pressure sensor technique are in excellent agreement with data obtained via direct observation. PMID:23941142

  14. NASA's X-Plane Database and Parametric Cost Model v 2.0

    NASA Technical Reports Server (NTRS)

    Sterk, Steve; Ogluin, Anthony; Greenberg, Marc

    2016-01-01

    The NASA Armstrong Cost Engineering Team with technical assistance from NASA HQ (SID)has gone through the full process in developing new CERs from Version #1 to Version #2 CERs. We took a step backward and reexamined all of the data collected, such as dependent and independent variables, cost, dry weight, length, wingspan, manned versus unmanned, altitude, Mach number, thrust, and skin. We used a well- known statistical analysis tool called CO$TAT instead of using "R" multiple linear or the "Regression" tool found in Microsoft Excel(TradeMark). We setup an "array of data" by adding 21" dummy variables;" we analyzed the standard error (SE) and then determined the "best fit." We have parametrically priced-out several future X-planes and compared our results to those of other resources. More work needs to be done in getting "accurate and traceable cost data" from historical X-plane records!

  15. Understanding north-western Mediterranean climate variability: a multi-proxy and multi-sequence approach based on wavelet analysis.

    NASA Astrophysics Data System (ADS)

    Azuara, Julien; Lebreton, Vincent; Jalali, Bassem; Sicre, Marie-Alexandrine; Sabatier, Pierre; Dezileau, Laurent; Peyron, Odile; Frigola, Jaime; Combourieu-Nebout, Nathalie

    2017-04-01

    Forcings and physical mechanisms underlying Holocene climate variability still remain poorly understood. Comparison of different paleoclimatic reconstructions using spectral analysis allows to investigate their common periodicities and helps to understand the causes of past climate changes. Wavelet analysis applied on several proxy time series from the Atlantic domain already revealed the first key-issues on the origin of Holocene climate variability. However the differences in duration, resolution and variance between the time-series are important issues for comparing paleoclimatic sequences in the frequency domain. This work compiles 7 paleoclimatic proxy records from 4 time-series from the north-western Mediterranean all ranging from 7000 to 1000 yrs cal BP: -pollen and clay mineral contents from the lagoonal sediment core PB06 recovered in southern France, -Sea Surface Temperatures (SST) derived from alkenones, concentration of terrestrial alkanes and their average chain length (ACL) from core KSGC-31_GolHo-1B recovered in the Gulf of Lion inner-shelf, - δ18O record from speleothems recovered in the Asiul Cave in north-western Spain, -grain size record from the deep basin sediment drift core MD99-2343 north of Minorca island. A comparison of their frequency content is proposed using wavelet analysis and cluster analysis of wavelet power spectra. Common cyclicities are assessed using cross-wavelet analysis. In addition, a new algorithm is used in order to propagate the age model errors within wavelet power spectra. Results are consistents with a non-stationnary Holocene climate variability. The Halstatt cycles (2000-2500 years) depicted in many proxies (ACL, errestrial alkanes and SSTs) demonstrate solar activity influence in the north-western Mediterranean climate. Cluster analysis shows that pollen and ACL proxies, both indicating changes in aridity, are clearly distinct from other proxies and share significant common periodicities around 1000 and 600 years, since the mid-Holocene. The 1000 years period is also evidenced in terrestrial alkanes and Minorca sediment drift grain size, which respectively indicate changes in the Rhône hydrology and changes in the north-western Mediterranean deep water formation. These findings suggests that an original climate driver influences the Gulf of Lion area. Finally, both clay mineral content from PB06, indicative of past storminess and δ18O record from the north western Iberia, related to precipitations, record the well known 1500 years period since the middle Holocene. The presence of this period, widely encountered in the Atlantic, highlights the link between the north-western Mediterranean and the Atlantic climate variability.

  16. Variability in the Length and Frequency of Steps of Sighted and Visually Impaired Walkers

    ERIC Educational Resources Information Center

    Mason, Sarah J.; Legge, Gordon E.; Kallie, Christopher S.

    2005-01-01

    The variability of the length and frequency of steps was measured in sighted and visually impaired walkers at three different paces. The variability was low, especially at the preferred pace, and similar for both groups. A model incorporating step counts and step frequency provides good estimates of the distance traveled. Applications to…

  17. Variable focal length deformable mirror

    DOEpatents

    Headley, Daniel [Albuquerque, NM; Ramsey, Marc [Albuquerque, NM; Schwarz, Jens [Albuquerque, NM

    2007-06-12

    A variable focal length deformable mirror has an inner ring and an outer ring that simply support and push axially on opposite sides of a mirror plate. The resulting variable clamping force deforms the mirror plate to provide a parabolic mirror shape. The rings are parallel planar sections of a single paraboloid and can provide an on-axis focus, if the rings are circular, or an off-axis focus, if the rings are elliptical. The focal length of the deformable mirror can be varied by changing the variable clamping force. The deformable mirror can generally be used in any application requiring the focusing or defocusing of light, including with both coherent and incoherent light sources.

  18. Asymmetry in Determinants of Running Speed During Curved Sprinting.

    PubMed

    Ishimura, Kazuhiro; Sakurai, Shinji

    2016-08-01

    This study investigates the potential asymmetries between inside and outside legs in determinants of curved running speed. To test these asymmetries, a deterministic model of curved running speed was constructed based on components of step length and frequency, including the distances and times of different step phases, takeoff speed and angle, velocities in different directions, and relative height of the runner's center of gravity. Eighteen athletes sprinted 60 m on the curved path of a 400-m track; trials were recorded using a motion-capture system. The variables were calculated following the deterministic model. The average speeds were identical between the 2 sides; however, the step length and frequency were asymmetric. In straight sprinting, there is a trade-off relationship between the step length and frequency; however, such a trade-off relationship was not observed in each step of curved sprinting in this study. Asymmetric vertical velocity at takeoff resulted in an asymmetric flight distance and time. The runners changed the running direction significantly during the outside foot stance because of the asymmetric centripetal force. Moreover, the outside leg had a larger tangential force and shorter stance time. These asymmetries between legs indicated the outside leg plays an important role in curved sprinting.

  19. The process of orthognathic care in an NHS region

    PubMed Central

    Parbatani, R; Williams, AC; Ireland, AJ; Sandy, JR

    2010-01-01

    INTRODUCTION The aim of this study was to evaluate, within an NHS region, the process of care and the standard of record for orthognathic patients. PATIENTS AND METHODS A retrospective analysis of the medical records of 372 patients who underwent orthognathic surgery 1 January 1995 and 31 April 2000 in the South West Region of the UK. RESULTS Most patients underwent joint orthodontic and maxillofacial planning and had third molars extracted under general anaesthesia prior to orthognathic surgery. There was a significant difference in the median operation times and length of stay for bimaxillary surgery (4 h/4 days) compared with single jaw surgery (2 h/3 days; P < 0.001). Just over 15% of patients required removal of internal fixation plates after surgery, with nearly 90% of these requiring a further episode of general anaesthesia. The level of record keeping and patient review was variable with no regional standardisation. CONCLUSIONS This study is evidence of a generally acceptable standard in the process of care, which was found to follow international and national practices. However, at the time of the study there was no regional protocol for patient records or patient review, highlighting the need for the establishment of a regional database. PMID:19887023

  20. Fission track length distributions in multi-system thermochronology (Invited)

    NASA Astrophysics Data System (ADS)

    Gleadow, A. J.; Seiler, C.

    2013-12-01

    Fission track length distributions contain a unique record of past temperature variations and therefore play a key role in low-temperature thermochronology, for which there is no exact equivalent in any other method. Confined track lengths closely approximate the true etchable ranges of latent fission tracks [1] and are therefore favoured for fission track studies, but they still have a number of practical limitations. These include small numbers of suitable tracks, especially when only horizontal confined tracks are measured. Using only track-in-track events for measurement further limits the sample size. These restrictions become acute for low track-density samples, where length measurements may be impossible. Irradiating the surface with 252Cf tracks [2] can substantially increase the number of confined tracks, but many researchers do not have access to a Cf source. An even more significant issue has emerged from inter-laboratory comparison experiments that demonstrate a disturbingly poor reproducibility of length measurements between observers [3], a problem compounded by a lack of standardisation in measurement techniques. As a result, individual observers may measure different positions for the end of a track, contributing significantly to variability, and consequently blurring the thermal histories obtained. New digital microscopes open up important opportunities for improved track length measurements by reducing restrictions on sample size, and eliminating some sources of inter-observer bias. We have developed a track length measurement system that enables precise determination of vertical as well as horizontal track dimensions, allowing 3D lengths to be obtained. Lengths are measured on captured image stacks that can be analysed easily and may also be shared, for greater standardisation between laboratories. Length measurements are highly reproducible between different observers using this system, suggesting that at least one source of variability can be eliminated. The selection of lengths for imaging, however, still remains a source of potential bias between observers. The new measurement system also enables measurement of 3D lengths of surface-intersecting ';semi-tracks', the distributions of which have been well understood theoretically [1,4], but have not been used in practice because of difficulties of measuring vertical dimensions on older microscopes. Semi-track lengths are, of course, a degraded measure compared to confined tracks because they are randomly truncated. However, this is more than compensated by their very much greater abundance, by a factor of >60, compared to confined tracks. They are also more amenable to semi- or fully-automated measurement techniques than confined tracks. Moreover the distribution characteristics of semi-track lengths relative to confined track lengths are well understood so that in principle the two types could be used together in modelling thermal histories. The implementation of these new approaches for track length measurement should significantly improve the precision and standardisation of track length measurements at every stage of their utilisation, from annealing studies to thermal history modelling of unknowns. [1] Galbraith (2003) Statistics for FT Analysis, Chapman & Hall [2] Donelick et al. (2005) Rev Min Geochem 58, 49-94 [3] Ketcham et al. (2009) Ear Planet Sci Lett 284, 504-515 [4] Jonckheere & Van den haute (1999) Rad Meas 30, 155-179

  1. Littrow-type external-cavity blue laser for holographic data storage.

    PubMed

    Tanaka, Tomiji; Takahashi, Kazuo; Sako, Kageyasu; Kasegawa, Ryo; Toishi, Mitsuru; Watanabe, Kenjiro; Samuels, David; Takeya, Motonobu

    2007-06-10

    An external-cavity laser with a wavelength of 405 nm and an output of 80 mW has been developed for holographic data storage. The laser has three states: the first is a perfect single mode, whose coherent length is 14 m; the second is a three-mode state with a coherent length of 3 mm; and the third is a six-mode state with a coherent length of 0.3 mm. The first and second states are available for angular-multiplexing recording; all states are available for coaxial multiplexing recording. Due to its short wavelength, the recording density is higher than that of a 532 nm laser.

  2. Is the problem list in the eye of the beholder? An exploration of consistency across physicians.

    PubMed

    Krauss, John C; Boonstra, Philip S; Vantsevich, Anna V; Friedman, Charles P

    2016-09-01

    Quantify the variability of patients' problem lists - in terms of the number, type, and ordering of problems - across multiple physicians and assess physicians' criteria for organizing and ranking diagnoses. In an experimental setting, 32 primary care physicians generated and ordered problem lists for three identical complex internal medicine cases expressed as detailed 2- to 4-page abstracts and subsequently expressed their criteria for ordering items in the list. We studied variability in problem list length. We modified a previously validated rank-based similarity measure, with range of zero to one, to quantify agreement between pairs of lists and calculate a single consensus problem list that maximizes agreement with each physician. Physicians' reasoning for the ordering of the problem lists was recorded. Subjects' problem lists were highly variable. The median problem list length was 8 (range: 3-14) for Case A, 10 (range: 4-20) for Case B, and 7 (range: 3-13) for Case C. The median indices of agreement - taking into account the length, content, and order of lists - over all possible physician pairings was 0.479, 0.371, 0.509, for Cases A, B, and C, respectively. The median agreements between the physicians' lists and the consensus list for each case were 0.683, 0.581, and 0.697 (for Cases A, B, and C, respectively).Out of a possible 1488 pairings, 2 lists were identical. Physicians most frequently ranked problem list items based on their acuity and immediate threat to health. The problem list is a physician's mental model of a patient's health status. These mental models were found to vary significantly between physicians, raising questions about whether problem lists created by individual physicians can serve their intended purpose to improve care coordination. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  3. Total direct cost, length of hospital stay, institutional discharges and their determinants from rehabilitation settings in stroke patients.

    PubMed

    Saxena, S K; Ng, T P; Yong, D; Fong, N P; Gerald, K

    2006-11-01

    Length of hospital stay (LOHS) is the largest determinant of direct cost for stroke care. Institutional discharges (acute care and nursing homes) from rehabilitation settings add to the direct cost. It is important to identify potentially preventable medical and non-medical reasons determining LOHS and institutional discharges to reduce the direct cost of stroke care. The aim of the study was to ascertain the total direct cost, LOHS, frequency of institutional discharges and their determinants from rehabilitation settings. Observational study was conducted on 200 stroke patients in two rehabilitation settings. The patients were examined for various socio-demographic, neurological and clinical variables upon admission to the rehabilitation hospitals. Information on total direct cost and medical complications during hospitalization were also recorded. The outcome variables measured were total direct cost, LOHS and discharges to institutions (acute care and nursing home facility) and their determinants. The mean and median LOHS in our study were 34 days (SD = 18) and 32 days respectively. LOHS and the cost of hospital stay were significantly correlated. The significant variables associated with LOHS on multiple linear regression analysis were: (i) severe functional impairment/functional dependence Barthel Index < or = 50, (ii) medical complications, (iii) first time stroke, (iv) unplanned discharges and (v) discharges to nursing homes. Of the stroke patients 19.5% had institutional discharges (22 to acute care and 17 to nursing homes). On multivariate analysis the significant predictors of discharges to institutions from rehabilitation hospitals were medical complications (OR = 4.37; 95% CI 1.01-12.53) and severe functional impairment/functional dependence. (OR = 5.90, 95% CI 2.32-14.98). Length of hospital stay and discharges to institutions from rehabilitation settings are significantly determined by medical complications. Importance of adhering to clinical pathway/protocol for stroke care is further discussed.

  4. NOAA's Scientific Data Stewardship Program

    NASA Astrophysics Data System (ADS)

    Bates, J. J.

    2004-12-01

    The NOAA mission is to understand and predict changes in the Earth's environment and conserve and manage coastal and marine resources to meet the Nation's economic, social and environmental needs. NOAA has responsibility for long-term archiving of the United States environmental data and has recently integrated several data management functions into a concept called Scientific Data Stewardship. Scientific Data Stewardship a new paradigm in data management consisting of an integrated suite of functions to preserve and exploit the full scientific value of NOAA's, and the world's, environmental data These functions include careful monitoring of observing system performance for long-term applications, the generation of authoritative long-term climate records from multiple observing platforms, and the proper archival of and timely access to data and metadata. NOAA has developed a conceptual framework to implement the functions of scientific data stewardship. This framework has five objectives: 1) develop real-time monitoring of all satellite observing systems for climate applications, 2) process large volumes of satellite data extending up to decades in length to account for systematic errors and to eliminate artifacts in the raw data (referred to as fundamental climate data records, FCDRs), 3) generate retrieved geophysical parameters from the FCDRs (referred to as thematic climate data records TCDRs) including combining observations from all sources, 4) conduct monitoring and research by analyzing data sets to uncover climate trends and to provide evaluation and feedback for steps 2) and 3), and 5) provide archives of metadata, FCDRs, and TCDRs, and facilitate distribution of these data to the user community. The term `climate data record' and related terms, such as climate data set, have been used for some time, but the climate community has yet to settle on a concensus definition. A recent United States National Academy of Sciences report recommends using the following definition: a climate data record (CDR) is a time series of measurements of sufficient length, consistency, and continuity to determine climate variability and change.

  5. Select injury-related variables are affected by stride length and foot strike style during running.

    PubMed

    Boyer, Elizabeth R; Derrick, Timothy R

    2015-09-01

    Some frontal plane and transverse plane variables have been associated with running injury, but it is not known if they differ with foot strike style or as stride length is shortened. To identify if step width, iliotibial band strain and strain rate, positive and negative free moment, pelvic drop, hip adduction, knee internal rotation, and rearfoot eversion differ between habitual rearfoot and habitual mid-/forefoot strikers when running with both a rearfoot strike (RFS) and a mid-/forefoot strike (FFS) at 3 stride lengths. Controlled laboratory study. A total of 42 healthy runners (21 habitual rearfoot, 21 habitual mid-/forefoot) ran overground at 3.35 m/s with both a RFS and a FFS at their preferred stride lengths and 5% and 10% shorter. Variables did not differ between habitual groups. Step width was 1.5 cm narrower for FFS, widening to 0.8 cm as stride length shortened. Iliotibial band strain and strain rate did not differ between foot strikes but decreased as stride length shortened (0.3% and 1.8%/s, respectively). Pelvic drop was reduced 0.7° for FFS compared with RFS, and both pelvic drop and hip adduction decreased as stride length shortened (0.8° and 1.5°, respectively). Peak knee internal rotation was not affected by foot strike or stride length. Peak rearfoot eversion was not different between foot strikes but decreased 0.6° as stride length shortened. Peak positive free moment (normalized to body weight [BW] and height [h]) was not affected by foot strike or stride length. Peak negative free moment was -0.0038 BW·m/h greater for FFS and decreased -0.0004 BW·m/h as stride length shortened. The small decreases in most variables as stride length shortened were likely associated with the concomitant wider step width. RFS had slightly greater pelvic drop, while FFS had slightly narrower step width and greater negative free moment. Shortening one's stride length may decrease or at least not increase propensity for running injuries based on the variables that we measured. One foot strike style does not appear universally better than the other; rather, different foot strike styles may predispose runners to different types of injuries. © 2015 The Author(s).

  6. Systematic correlation of environmental exposure and physiological and self-reported behaviour factors with leukocyte telomere length.

    PubMed

    Patel, Chirag J; Manrai, Arjun K; Corona, Erik; Kohane, Isaac S

    2017-02-01

    It is hypothesized that environmental exposures and behaviour influence telomere length, an indicator of cellular ageing. We systematically associated 461 indicators of environmental exposures, physiology and self-reported behaviour with telomere length in data from the US National Health and Nutrition Examination Survey (NHANES) in 1999-2002. Further, we tested whether factors identified in the NHANES participants are also correlated with gene expression of telomere length modifying genes. We correlated 461 environmental exposures, behaviours and clinical variables with telomere length, using survey-weighted linear regression, adjusting for sex, age, age squared, race/ethnicity, poverty level, education and born outside the USA, and estimated the false discovery rate to adjust for multiple hypotheses. We conducted a secondary analysis to investigate the correlation between identified environmental variables and gene expression levels of telomere-associated genes in publicly available gene expression samples. After correlating 461 variables with telomere length, we found 22 variables significantly associated with telomere length after adjustment for multiple hypotheses. Of these varaibales, 14 were associated with longer telomeres, including biomarkers of polychlorinated biphenyls([PCBs; 0.1 to 0.2 standard deviation (SD) increase for 1 SD increase in PCB level, P  < 0.002] and a form of vitamin A, retinyl stearate. Eight variables associated with shorter telomeres, including biomarkers of cadmium, C-reactive protein and lack of physical activity. We could not conclude that PCBs are correlated with gene expression of telomere-associated genes. Both environmental exposures and chronic disease-related risk factors may play a role in telomere length. Our secondary analysis found no evidence of association between PCBs/smoking and gene expression of telomere-associated genes. All correlations between exposures, behaviours and clinical factors and changes in telomere length will require further investigation regarding biological influence of exposure. © The Author 2016. Published by Oxford University Press on behalf of the International Epidemiological Association

  7. Spatiotemporal correlation structure of the Earth's surface temperature

    NASA Astrophysics Data System (ADS)

    Fredriksen, Hege-Beate; Rypdal, Kristoffer; Rypdal, Martin

    2015-04-01

    We investigate the spatiotemporal temperature variability for several gridded instrumental and climate model data sets. The temporal variability is analysed by estimating the power spectral density and studying the differences between local and global temperatures, land and sea, and among local temperature records at different locations. The spatiotemporal correlation structure is analysed through cross-spectra that allow us to compute frequency-dependent spatial autocorrelation functions (ACFs). Our results are then compared to theoretical spectra and frequency-dependent spatial ACFs derived from a fractional stochastic-diffusive energy balance model (FEBM). From the FEBM we expect both local and global temperatures to have a long-range persistent temporal behaviour, and the spectral exponent (β) is expected to increase by a factor of two when going from local to global scales. Our comparison of the average local spectrum and the global spectrum shows good agreement with this model, although the FEBM has so far only been studied for a pure land planet and a pure ocean planet, respectively, with no seasonal forcing. Hence it cannot capture the substantial variability among the local spectra, in particular between the spectra for land and sea, and for equatorial and non-equatorial temperatures. Both models and observation data show that land temperatures in general have a low persistence, while sea surface temperatures show a higher, and also more variable degree of persistence. Near the equator the spectra deviate from the power-law shape expected from the FEBM. Instead we observe large variability at time scales of a few years due to ENSO, and a flat spectrum at longer time scales, making the spectrum more reminiscent of that of a red noise process. From the frequency-dependent spatial ACFs we observe that the spatial correlation length increases with increasing time scale, which is also consistent with the FEBM. One consequence of this is that longer-lasting structures must also be wider in space. The spatial correlation length is also observed to be longer for land than for sea. The climate model simulations studied are mainly CMIP5 control runs of length 500-1000 yr. On time scales up to several centuries we do not observe that the difference between the local and global spectral exponents vanish. This also follows from the FEBM and shows that the dynamics is spatiotemporal (not just temporal) even on these time scales.

  8. Factors associated with early cyclicity in postpartum dairy cows.

    PubMed

    Vercouteren, M M A A; Bittar, J H J; Pinedo, P J; Risco, C A; Santos, J E P; Vieira-Neto, A; Galvão, K N

    2015-01-01

    The objective of this study was to evaluate factors associated with resumption of ovarian cyclicity within 21 days in milk (DIM) in dairy cows. Cows (n=768) from 2 herds in north Florida had their ovaries scanned at 17±3, 21±3, and 24±3 DIM. Cows that had a corpus luteum ≥20mm at 17±3 or at 21±3 DIM or that had a corpus luteum <20mm in 2 consecutive examinations were determined to be cyclic by 21±3 DIM. The following information was collected for up to 14 DIM: calving season, parity, calving problems, metabolic problems, metritis, mastitis, digestive problems, lameness, body weight loss, dry period length, and average daily milk yield. Body condition was scored at 17±3 DIM. Multivariable mixed logistic regression analysis was performed using the GLIMMIX procedure of SAS. Variables with P≤0.2 were considered in each model. Herd was included as a random variable. Three models were constructed: model 1 included all cows, model 2 included only cows from dairy 1 that had daily body weights available, and model 3 included only multiparous cows with a previous dry period length recorded. In model 1, variables associated with greater cyclicity by 21±3 DIM were calving in the summer and fall rather than in the winter or spring, being multiparous rather than primiparous, and not having metabolic or digestive problems. In model 2, variables associated with greater cyclicity by 21±3 DIM were calving in the summer and fall, not having metritis or digestive problems and not losing >28 kg of BW within 14 DIM. In model 3, variables associated with greater cyclicity by 21±3 DIM were absence of metabolic problems and dry period ≤76 d. In summary, cyclicity by 21±3 DIM was negatively associated with calving in winter or spring, primiparity, metritis, metabolic or digestive problems, loss of >28 kg of body weight, and a dry period >76d. Strategies preventing extended dry period length and loss of BW, together with reductions in the incidence of metritis as well as metabolic and digestive problems should improve early cyclicity postpartum. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  9. Admission time to hospital: a varying standard for a critical definition for admissions to an intensive care unit from the emergency department.

    PubMed

    Nanayakkara, Shane; Weiss, Heike; Bailey, Michael; van Lint, Allison; Cameron, Peter; Pilcher, David

    2014-11-01

    Time spent in the emergency department (ED) before admission to hospital is often considered an important key performance indicator (KPI). Throughout Australia and New Zealand, there is no standard definition of 'time of admission' for patients admitted through the ED. By using data submitted to the Australian and New Zealand Intensive Care Society Adult Patient Database, the aim was to determine the differing methods used to define hospital admission time and assess how these impact on the calculation of time spent in the ED before admission to an intensive care unit (ICU). Between March and December of 2010, 61 hospitals were contacted directly. Decision methods for determining time of admission to the ED were matched to 67,787 patient records. Univariate and multivariate analyses were conducted to assess the relationship between decision method and the reported time spent in the ED. Four mechanisms of recording time of admission were identified, with time of triage being the most common (28/61 hospitals). Reported median time spent in the ED varied from 2.5 (IQR 0.83-5.35) to 5.1 h (2.82-8.68), depending on the decision method. After adjusting for illness severity, hospital type and location, decision method remained a significant factor in determining measurement of ED length of stay. Different methods are used in Australia and New Zealand to define admission time to hospital. Professional bodies, hospitals and jurisdictions should ensure standardisation of definitions for appropriate interpretation of KPIs as well as for the interpretation of studies assessing the impact of admission time to ICU from the ED. WHAT IS KNOWN ABOUT THE TOPIC?: There are standards for the maximum time spent in the ED internationally, but these standards vary greatly across Australia. The definition of such a standard is critically important not only to patient care, but also in the assessment of hospital outcomes. Key performance indicators rely on quality data to improve decision-making. WHAT DOES THIS PAPER ADD?: This paper quantifies the variability of times measured and analyses why the variability exists. It also discusses the impact of this variability on assessment of outcomes and provides suggestions to improve standardisation. WHAT ARE THE IMPLICATIONS FOR PRACTITIONERS?: This paper provides a clearer view on standards regarding length of stay in the ICU, highlighting the importance of key performance indicators, as well as the quality of data that underlies them. This will lead to significant changes in the way we standardise and interpret data regarding length of stay.

  10. Recurrence quantification analysis of human postural fluctuations in older fallers and non-fallers.

    PubMed

    Ramdani, Sofiane; Tallon, Guillaume; Bernard, Pierre Louis; Blain, Hubert

    2013-08-01

    We investigate postural sway data dynamics in older adult fallers and non-fallers. Center of pressure (COP) signals were recorded during quiet standing in 28 older adults. The subjects were divided in two groups: with and without history of falls. COP time series were analyzed using recurrence quantification analysis (RQA) in both anteroposterior and mediolateral (ML) directions. Classical stabilometric variables (path length and range) were also computed. The results showed that RQA outputs quantifying predictability of COP fluctuations and Shannon entropy of recurrence plot diagonal line length distribution, were significantly higher in fallers, only for ML direction. In addition, the range of ML COP signals was also significantly higher in fallers. This result is in accordance with some findings of the literature and could be interpreted as an increased hip strategy in fallers. The RQA results seem coherent with the theory of loss of complexity with aging and disease. Our results suggest that RQA is a promising approach for the investigation of COP fluctuations in a frail population.

  11. Electrogram Morphology Recurrence Patterns during Atrial Fibrillation

    PubMed Central

    Ng, Jason; Gordon, David; Passman, Rod S.; Knight, Bradley P.; Arora, Rishi; Goldberger, Jeffrey J.

    2014-01-01

    Background Traditional mapping of atrial fibrillation (AF) is limited by changing electrogram morphologies and variable cycle lengths. Objective We tested the hypothesis that morphology recurrence plot analysis would identify sites of stable and repeatable electrogram morphology patterns. Methods AF electrograms recorded from left atrial (LA) and right atrial (RA) sites in 19 patients (10 male, 59±10 years old) prior to AF ablation were analyzed. Morphology recurrence plots for each electrogram recording were created by cross-correlation of each automatically detected activation with every other activation in the recording. A recurrence percentage, the percentage of the most common morphology, and the mean cycle length of activations with the most common morphology (CLR) were computed. Results The morphology recurrence plots commonly showed checkerboard patterns of alternating high and low cross correlation values indicating periodic recurrences in morphologies. The mean recurrence percentage for all sites and all patients was 38±25%. The highest recurrence percentage per patient averaged 83±17%. The highest recurrence percentage was located in the RA in 5 patients and in the LA in 14 patients. Patients with sites of shortest CLR in the LA and RA had ablation failure rates of 25% and 100%, respectively (HR=4.95; p=0.05). Conclusions A new technique to characterize electrogram morphology recurrence demonstrated that there is a distribution of sites with high and low repeatability of electrogram morphologies. Sites with rapid activation of highly repetitive morphology patterns may be critical to sustaining AF. Further testing of this approach to map and ablate AF sources is warranted. PMID:25101485

  12. Comparative glacio-climatological analysis of mass balance variability along the geographical margin of Europe

    NASA Astrophysics Data System (ADS)

    Lehoczky, Annamária; Kern, Zoltán; Pongrácz, Rita

    2014-05-01

    Glacio-climatological studies recognise glacier mass balance changes as high-confident climate indicators. The climatic sensitivity of a glacier does not simply depend on regional climate variability but also influenced via large- and mesoscale atmospheric circulation patterns. This study focuses on recent changes in the mass balance using records from three border regions of Europe, and investigates the relationships between the seasonal mass balance components, regional climatic conditions, and distant atmospheric forcing. Since glaciers in different macro-climatological conditions (i.e., mid-latitudes or high-latitudes, dry-continental or maritime regions) may present strongly diverse mass balance characteristics, the three analysed regions were selected from different glacierised macroregions (using the database of the World Glacier Monitoring Service). These regions belong to the Caucasus Mountains (Central Europe macroregion), the Polar Ural (Northern Asia macroregion), and Svalbard (Arctic Islands macroregion). The analysis focuses on winter, summer, and annual mass balance series of eight glaciers. The climatic variables (atmospheric pressure, air temperature, precipitation) and indices of teleconnection patterns (e.g., North Atlantic Oscillation, Pacific Decadal Oscillation) are used from the gridded databases of the University of East Anglia, Climatic Research Unit and the National Oceanic and Atmospheric Administration, National Center for Environmental Prediction. However, the period and length of available mass balance data in the selected regions vary greatly (the first full record is in 1958, Polar Ural; the last is in 2010, Caucasus Mountains), a comparative analysis can be carried out for the period of 1968-1981. Since glaciers from different regions respond to large- and mesoscale climatic forcings differently, and because the mass balance of glaciers within a region often co-vary, our specific objectives are (i) to examine the variability and the integrative climatic signal in the averaged mass balance records of the selected regions; (ii) to analyse the possible coupling between the mass balance and climatic variables, including the dominant patterns of Northern Hemisphere climate variability; and (iii) to compare the main characteristics of the three regions. Furthermore, (iv) a short discussion is given considering the significant decreasing trend of the cumulative annual mass balances in every region under the detected climatic changes in the second half of the 20th century. Preliminary results suggest that the strongest teleconnection links could be between winter mass balance and winter NAO for the Polar Ural (r=0.46, p<0.05), and between annual mass balance and PDO for Svalbard (r=-0.43, p<0.05). Neither seasonal, nor annual mass balance records showed significant correlation with any of the examined circulation indices for the Caucasus.

  13. Ideal proportion of roughage and concentrate for Malpura ewes to adapt and reproduce in a semi-arid tropical environment.

    PubMed

    Indu, Shekhawat; Sejian, Veerasamy; Kumar, Davendra; Pareek, Arvind; Naqvi, Syed Mohammad Krusheed

    2015-12-01

    The study was designed to identify the most appropriate roughage to concentrate ratio for Malpura ewes under semi-arid tropical environments. The study was conducted for a period of 35 days and included 30 (2 years old) non-pregnant Malpura ewes weighing between 30 and 35 kg. Estrus synchronization was carried out in all the animals using indigenously developed intravaginal sponges impregnated with progesterone. The ewes were randomly divided into three groups (n = 10/group) namely R50 (n = 10; roughage to concentrate, 50:50), R60 (n = 10; roughage to concentrate, 60:40), and R70 (n = 10; roughage to concentrate, 70:30). Individual feed and water intake was recorded on a daily basis throughout the course of the study. Growth variables, physiological responses, blood metabolites, and endocrine responses were estimated at weekly intervals. Results of the study indicated that nutritional treatment significantly influenced growth variables including body weight (p < 0.01), BCS (p < 0.01), feed intake (p < 0.05), and water intake (p < 0.01) among the different treatment groups. The highest growth variables were recorded in R50 whereas the lowest were in R70. Both respiration rate (p < 0.01) and plasma estradiol levels (p < 0.05) also showed a similar trend as that of the growth variables. However, growth hormone (p < 0.01), T3 (p < 0.01), Hb (p < 0.01), glucose (p < 0.05), and estrus duration (p < 0.05) demonstrated a reverse trend with highest values recorded in R70 and lowest in R50. However, the nutritional treatment did not influence pulse rate, rectal temperature, T4, progesterone, PCV, total cholesterol, total protein, albumin, estrus%, and estrus cycle length. Since the additional concentrate supplementation in R50 and R60 did not improve the production variables, it can be concluded that providing 70 % roughage and 30 % concentrate could be a more appropriate and economically feasible ration composition for Malpura ewes reared in semi-arid tropical environments.

  14. Plants and soil microbes respond to recent warming on the Antarctic Peninsula

    NASA Astrophysics Data System (ADS)

    Amesbury, M. J.; Royles, J.; Hodgson, D.; Convey, P.; Griffiths, H.; Charman, D.

    2013-12-01

    The Antarctic Peninsula is one of the most rapidly warming regions on Earth, with temperature increases of as much as 3°C recorded since the 1950s. However, the longer-term context of this change is limited and existing records are not suitably located to be able to trace the spatial signature of change over time. This paper will present the first published results from a wider project exploiting peat moss banks spanning 10 degrees of latitude along the Antarctic Peninsula as an archive of late Holocene climate variability. These moss banks are ideal archives for palaeoclimate research as they are well-preserved by freezing, generally monospecific, easily dated by radiocarbon techniques and have sufficiently high accumulation rates to permit decadal resolution. A unique time series of past moss growth and soil microbial activity has been produced from a 150 year old moss bank at Lazarev Bay, Alexander Island, a site at the southern limit of significant plant growth in the Antarctic Peninsula region. We use accumulation rates, cellulose δ13C and fossil testate amoebae to provide an indication of ecosystem productivity. We show that both moss and microbial population growth rates rose rapidly in the 1960s, consistent with temperature change, although recently may have stalled, concurrent with other evidence. The increase in terrestrial plant growth rates and soil microbial activity is unprecedented in the last 150 years. The observed relationship between moss growth, microbial activity and climate at Lazarev Bay suggests that moss bank records have the potential to test the regional expression of temperature variability shown by instrumental data on the Antarctic Peninsula over centennial to millennial timescales, by providing long-term records of summer growth conditions, complementing the more distant and widely dispersed ice core records. As a result, we will conclude by placing the Lazarev Bay record into the wider context of the latest progress of analysis of moss bank cores obtained along the length of the Antarctic Peninsula.

  15. A Satellite-Derived Climate-Quality Data Record of the Clear-Sky Surface Temperature of the Greenland Ice Sheet

    NASA Technical Reports Server (NTRS)

    Hall, Dorothy K.; Comiso, Josefino C.; DiGirolamo, Nikolo E.; Shuman, Christopher A.; Key, Jeffrey R.; Koenig, Lora S.

    2012-01-01

    We have developed a climate-quality data record of the clear-sky surface temperature of the Greenland Ice Sheet using the Moderate-Resolution Imaging Spectroradiometer (MODIS) ice-surface temperature (1ST) algorithm. A climate-data record (CDR) is a time series of measurements of sufficient length, consistency, and continuity to determine climate variability and change. We present daily and monthly MODIS ISTs of the Greenland Ice Sheet beginning on 1 March 2000 and continuing through 31 December 2010 at 6.25-km spatial resolution on a polar stereographic grid. This record will be elevated in status to a CDR when at least nine more years of data become available either from MODIS Terra or Aqua, or from the Visible Infrared Imager Radiometer Suite (VIIRS) to be launched in October 2011. Our ultimate goal is to develop a CDR that starts in 1981 with the Advanced Very High Resolution (AVHRR) Polar Pathfinder (APP) dataset and continues with MODIS data from 2000 to the present, and into the VIIRS era. Differences in the APP and MODIS cloud masks have so far precluded the current 1ST records from spanning both the APP and MODIS time series in a seamless manner though this will be revisited when the APP dataset has been reprocessed. The complete MODIS 1ST daily and monthly data record is available online.

  16. Environmental and genetic factors affecting milk yield and quality in three Italian sheep breeds.

    PubMed

    Selvaggi, Maria; D'Alessandro, Angela Gabriella; Dario, Cataldo

    2017-02-01

    The aims of the study described in the Research Communication were to determine the level of influence of some environmental factors on milk yield and quality traits, including lactose, and lactation length in ewes belonging to three different Italian breeds and to estimate the heritability for the same traits. A total of 2138 lactation records obtained from 535 ewes belonging to three different Italian breeds (Comisana, Leccese, and Sarda) were used. Breed significantly affected all of the considered traits. Moreover, year of lambing affected milk yield and lactation length without influence on milk quality traits. Parity affected significantly only the milk yield, whereas type of birth showed its effect on milk yield, fat, protein, and lactose yield. On the whole, the presently reported heritability estimates are within the range of those already obtained in other dairy breeds by other authors, with values for lactation length being very low in all the investigated populations. Considering the heritability estimates for lactose content and yield, to the best of our knowledge, there is a lack of information on these parameters in ovine species and this is the first report on heritability of lactose content and yield in dairy sheep breeds. Our results suggest that genetic variability for milk traits other than lactation length is adequate for selection indicating a good response to selection in these breeds.

  17. Factors associated with length of hospital stay among HIV positive and HIV negative patients with tuberculosis in Brazil.

    PubMed

    Gonçalves, Maria Jacirema Ferreira; Ferreira, Alaidistania A

    2013-01-01

    Identify and analyze the factors associated to length of hospital stay among HIV positive and HIV negative patients with tuberculosis in Manaus city, state of Amazonas, Brazil, in 2010. Epidemiological study with primary data obtained from monitoring of hospitalized patients with tuberculosis in Manaus. Data were collected by interviewing patients and analyzing medical records, according to the following study variables age, sex, co-morbidities, education, race, income, lifestyle, history of previous treatment or hospitalization due to tuberculosis, treatment regimen, adverse reactions, smear test, clinical form, type of discharge, and length of hospital stay. The associated factors were identified through chi-square or t-Student test at a 5% significance level. Income from 1 to 3 minimum wages (P = 0.028), pulmonary tuberculosis form (P = 0.011), negative smear test or no information in this regard (P = 0.014), initial 6-month treatment scheme (P = 0.029), and adverse drug reactions (P = 0.021) were associated to prolonged hospital stay in HIV positive patients. We found out that although there were no significant differences in the length of hospital stay in HIV positive patients, all factors significantly associated to prolonged hospital stay occurred in this group of patients. This finding corroborates other studies indicating the severity of tuberculosis in HIV patients, which may also contribute to lengthen their hospital stay.

  18. Experience with compound words influences their processing: An eye movement investigation with English compound words.

    PubMed

    Juhasz, Barbara J

    2016-11-14

    Recording eye movements provides information on the time-course of word recognition during reading. Juhasz and Rayner [Juhasz, B. J., & Rayner, K. (2003). Investigating the effects of a set of intercorrelated variables on eye fixation durations in reading. Journal of Experimental Psychology: Learning, Memory and Cognition, 29, 1312-1318] examined the impact of five word recognition variables, including familiarity and age-of-acquisition (AoA), on fixation durations. All variables impacted fixation durations, but the time-course differed. However, the study focused on relatively short, morphologically simple words. Eye movements are also informative for examining the processing of morphologically complex words such as compound words. The present study further examined the time-course of lexical and semantic variables during morphological processing. A total of 120 English compound words that varied in familiarity, AoA, semantic transparency, lexeme meaning dominance, sensory experience rating (SER), and imageability were selected. The impact of these variables on fixation durations was examined when length, word frequency, and lexeme frequencies were controlled in a regression model. The most robust effects were found for familiarity and AoA, indicating that a reader's experience with compound words significantly impacts compound recognition. These results provide insight into semantic processing of morphologically complex words during reading.

  19. Predictive Variables of Half-Marathon Performance for Male Runners.

    PubMed

    Gómez-Molina, Josué; Ogueta-Alday, Ana; Camara, Jesus; Stickley, Christoper; Rodríguez-Marroyo, José A; García-López, Juan

    2017-06-01

    The aims of this study were to establish and validate various predictive equations of half-marathon performance. Seventy-eight half-marathon male runners participated in two different phases. Phase 1 (n = 48) was used to establish the equations for estimating half-marathon performance, and Phase 2 (n = 30) to validate these equations. Apart from half-marathon performance, training-related and anthropometric variables were recorded, and an incremental test on a treadmill was performed, in which physiological (VO 2max , speed at the anaerobic threshold, peak speed) and biomechanical variables (contact and flight times, step length and step rate) were registered. In Phase 1, half-marathon performance could be predicted to 90.3% by variables related to training and anthropometry (Equation 1), 94.9% by physiological variables (Equation 2), 93.7% by biomechanical parameters (Equation 3) and 96.2% by a general equation (Equation 4). Using these equations, in Phase 2 the predicted time was significantly correlated with performance (r = 0.78, 0.92, 0.90 and 0.95, respectively). The proposed equations and their validation showed a high prediction of half-marathon performance in long distance male runners, considered from different approaches. Furthermore, they improved the prediction performance of previous studies, which makes them a highly practical application in the field of training and performance.

  20. Exploring the use of mothers' own milk as oral care for mechanically ventilated very low-birth-weight preterm infants.

    PubMed

    Thibeau, Shelley; Boudreaux, Cynthia

    2013-06-01

    The purpose of this study was to explore the use of mothers' own milk (colostrums, transitional milk, and mature milk) as oral care in the ventilator-associated pneumonia (VAP)-prevention bundle of mechanically ventilated preterm infants weighing 1500 g or less. Mechanically ventilated preterm infants weighing 1500 g or less admitted to a regional level III NICU in the Gulf South between January 1, 2006, and December 31, 2009. Retrospective descriptive. Oral care with mothers' own milk was implemented as part of the VAP-prevention bundle in the neonatal intensive care unit in the fourth quarter of 2007. Using retrospective deidentified data retrieved from the electronic medical record, the primary and secondary outcome variables were collected among eligible infants (≤1500 g) admitted January 1, 2006, to December 31, 2007 (before implementation) and January 1, 2008, to December 31, 2009 (after implementation). Sample characteristics, including infant gestational age, birth weight, and gender, as well as maternal age, type of delivery, and incidence of maternal chorioamnionitis, were also collected. Data analysis included frequencies and distributions to summarize sample characteristics and variables of interest. Appropriate tests for differences were conducted on outcome variables between the before and after groups of the human milk oral care intervention. The feasibility outcome variable included nursing compliance with the oral care procedure. The safety outcome variable included record of any adverse events associated with the oral care procedure. The efficacy health outcomes included the rate of positive tracheal aspirates, positive blood cultures, the number of ventilator days, and length of stay. Infant age (26.1-26.6 weeks) and weight (840-863 g) were similar in the before (n = 70) and after (n = 68) sample subjects. There were no statistically significant differences in ventilator days, χ² (46, n = 115) = 46.22, P = .46, and length of stay, χ (75, n = 115) = 78.78, P = .36, between groups. Although the rate of positive tracheal aspirates and positive blood cultures reduced after implementation of oral care with mothers' own milk, these differences were not statistically significant (U(47) = 250, z = -7.1, P = .48; U(47) = 217.5, z = -1.44, P = .15). There were no statistically significant differences in the rates of positive tracheal aspirates and blood cultures after implementation of oral care with mothers' own milk. The findings of this study suggest that using mothers' own milk as part of the VAP-prevention bundle is a feasible and safe practice; however, further research is needed to determine the immunological benefits of this practice.

  1. Algorithmic information theory and the hidden variable question

    NASA Technical Reports Server (NTRS)

    Fuchs, Christopher

    1992-01-01

    The admissibility of certain nonlocal hidden-variable theories are explained via information theory. Consider a pair of Stern-Gerlach devices with fixed nonparallel orientations that periodically perform spin measurements on identically prepared pairs of electrons in the singlet spin state. Suppose the outcomes are recorded as binary strings l and r (with l sub n and r sub n denoting their n-length prefixes). The hidden-variable theories considered here require that there exists a recursive function which may be used to transform l sub n into r sub n for any n. This note demonstrates that such a theory cannot reproduce all the statistical predictions of quantum mechanics. Specifically, consider an ensemble of outcome pairs (l,r). From the associated probability measure, the Shannon entropies H sub n and H bar sub n for strings l sub n and pairs (l sub n, r sub n) may be formed. It is shown that such a theory requires that the absolute value of H bar sub n - H sub n be bounded - contrasting the quantum mechanical prediction that it grow with n.

  2. Is there more than one circadian clock in humans? Evidence from fractional desynchronization studies.

    PubMed Central

    Folkard, S; Minors, D S; Waterhouse, J M

    1984-01-01

    Three groups of four healthy volunteers lived in an isolation unit for 24 days. During this time they lived by a clock which, unknown to themselves, ran progressively faster so that, by real time, the 'day' decreased from 24.0 to 22.0 h in length. Throughout this protocol, the subjects lived a regular regimen of sleep, waking and meals based upon their 'local' time clock. They collected regular urine samples that were analysed for a variety of constituents. Rectal temperature was also recorded automatically throughout. The effects of such a protocol upon circadian rhythmicity in these variables were investigated by a variety of techniques including cosinor analysis. The results showed that the temperature rhythm was less able to adjust to a shortening 'day' than were the urinary variables, with the possible exception of potassium; that is, the protocol forced an internal desynchronization to exist between different variables. These results are discussed in terms of both the possibility that more than one internal circadian clock might exist and the direct effect that sleep exerts upon the expression of circadian rhythms. PMID:6512693

  3. Emergency department length of stay for ethanol intoxication encounters.

    PubMed

    Klein, Lauren R; Driver, Brian E; Miner, James R; Martel, Marc L; Cole, Jon B

    2017-12-08

    Emergency Department (ED) encounters for ethanol intoxication are becoming increasingly common. The purpose of this study was to explore factors associated with ED length of stay (LOS) for ethanol intoxication encounters. This was a multi-center, retrospective, observational study of patients presenting to the ED for ethanol intoxication. Data were abstracted from the electronic medical record. To explore factors associated with ED LOS, we created a mixed-effects generalized linear model. We identified 18,664 eligible patients from 6 different EDs during the study period (2012-2016). The median age was 37years, 69% were male, and the median ethanol concentration was 213mg/dL. Median LOS was 348min (range 43-1658). Using a mixed-effects generalized linear model, independent variables associated with a significant increase in ED LOS included use of parenteral sedation (beta=0.30, increase in LOS=34%), laboratory testing (beta=0.21, increase in LOS=23%), as well as the hour of arrival to the ED, such that patients arriving to the ED during evening hours (between 18:00 and midnight) had up to an 86% increase in LOS. Variables not significantly associated with an increase in LOS included age, gender, ethanol concentration, psychiatric disposition, using the ED frequently for ethanol intoxication, CT use, and daily ED volume. Variables such as diagnostic testing, treatments, and hour of arrival may influence ED LOS in patients with acute ethanol intoxication. Identification and further exploration of these factors may assist in developing hospital and community based improvements to modify LOS in this population. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Posterolateral Trajectories Favor a Longer Motor Domain in Subthalamic Nucleus Deep Brain Stimulation for Parkinson Disease.

    PubMed

    Tamir, Idit; Marmor-Levin, Odeya; Eitan, Renana; Bergman, Hagai; Israel, Zvi

    2017-10-01

    The clinical outcome of patients with Parkinson disease (PD) who undergo subthalamic nucleus (STN) deep brain stimulation (DBS) is, in part, determined by the length of the electrode trajectory through the motor STN domain, the dorsolateral oscillatory region (DLOR). Trajectory length has been found to correlate with the stimulation-related improvement in patients' motor function (estimated by part III of the United Parkinson's Disease Rating Scale [UPDRS]). Therefore, it seems that ideally trajectories should have maximal DLOR length. We retrospectively studied the influence of various anatomic aspects of the brains of patients with PD and the geometry of trajectories planned on the length of the DLOR and STN recorded during DBS surgery. We examined 212 trajectories and 424 microelectrode recording tracks in 115 patients operated on in our center between 2010 and 2015. We found a strong correlation between the length of the recorded DLOR and STN. Trajectories that were more lateral and/or posterior in orientation had a longer STN and DLOR pass, although the DLOR/STN fraction length remained constant. The STN target was more lateral when the third ventricle was wider, and the latter correlated with older age and male gender. Trajectory angles correlate with the recorded STN and DLOR lengths, and should be altered toward a more posterolateral angle in older patients and atrophied brains to compensate for the changes in STN location and geometry. These fine adjustments should yield a longer motor domain pass, thereby improving the patient's predicted outcome. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Gait characteristics under different walking conditions: Association with the presence of cognitive impairment in community-dwelling older people

    PubMed Central

    Fransen, Erik; Perkisas, Stany; Verhoeven, Veronique; Beauchet, Olivier; Remmen, Roy

    2017-01-01

    Background Gait characteristics measured at usual pace may allow profiling in patients with cognitive problems. The influence of age, gender, leg length, modified speed or dual tasking is unclear. Methods Cross-sectional analysis was performed on a data registry containing demographic, physical and spatial-temporal gait parameters recorded in five walking conditions with a GAITRite® electronic carpet in community-dwelling older persons with memory complaints. Four cognitive stages were studied: cognitively healthy individuals, mild cognitive impaired patients, mild dementia patients and advanced dementia patients. Results The association between spatial-temporal gait characteristics and cognitive stages was the most prominent: in the entire study population using gait speed, steps per meter (translation for mean step length), swing time variability, normalised gait speed (corrected for leg length) and normalised steps per meter at all five walking conditions; in the 50-to-70 years old participants applying step width at fast pace and steps per meter at usual pace; in the 70-to-80 years old persons using gait speed and normalised gait speed at usual pace, fast pace, animal walk and counting walk or steps per meter and normalised steps per meter at all five walking conditions; in over-80 years old participants using gait speed, normalised gait speed, steps per meter and normalised steps per meter at fast pace and animal dual-task walking. Multivariable logistic regression analysis adjusted for gender predicted in two compiled models the presence of dementia or cognitive impairment with acceptable accuracy in persons with memory complaints. Conclusion Gait parameters in multiple walking conditions adjusted for age, gender and leg length showed a significant association with cognitive impairment. This study suggested that multifactorial gait analysis could be more informative than using gait analysis with only one test or one variable. Using this type of gait analysis in clinical practice could facilitate screening for cognitive impairment. PMID:28570662

  6. Two Independent Contributions to Step Variability during Over-Ground Human Walking

    PubMed Central

    Collins, Steven H.; Kuo, Arthur D.

    2013-01-01

    Human walking exhibits small variations in both step length and step width, some of which may be related to active balance control. Lateral balance is thought to require integrative sensorimotor control through adjustment of step width rather than length, contributing to greater variability in step width. Here we propose that step length variations are largely explained by the typical human preference for step length to increase with walking speed, which itself normally exhibits some slow and spontaneous fluctuation. In contrast, step width variations should have little relation to speed if they are produced more for lateral balance. As a test, we examined hundreds of overground walking steps by healthy young adults (N = 14, age < 40 yrs.). We found that slow fluctuations in self-selected walking speed (2.3% coefficient of variation) could explain most of the variance in step length (59%, P < 0.01). The residual variability not explained by speed was small (1.5% coefficient of variation), suggesting that step length is actually quite precise if not for the slow speed fluctuations. Step width varied over faster time scales and was independent of speed fluctuations, with variance 4.3 times greater than that for step length (P < 0.01) after accounting for the speed effect. That difference was further magnified by walking with eyes closed, which appears detrimental to control of lateral balance. Humans appear to modulate fore-aft foot placement in precise accordance with slow fluctuations in walking speed, whereas the variability of lateral foot placement appears more closely related to balance. Step variability is separable in both direction and time scale into balance- and speed-related components. The separation of factors not related to balance may reveal which aspects of walking are most critical for the nervous system to control. PMID:24015308

  7. Buccal telomere length and its associations with cortisol, heart rate variability, heart rate, and blood pressure responses to an acute social evaluative stressor in college students.

    PubMed

    Woody, Alex; Hamilton, Katrina; Livitz, Irina E; Figueroa, Wilson S; Zoccola, Peggy M

    2017-05-01

    Understanding the relationship between stress and telomere length (a marker of cellular aging) is of great interest for reducing aging-related disease and death. One important aspect of acute stress exposure that may underlie detrimental effects on health is physiological reactivity to the stressor. This study tested the relationship between buccal telomere length and physiological reactivity (salivary cortisol reactivity and total output, heart rate (HR) variability, blood pressure, and HR) to an acute psychosocial stressor in a sample of 77 (53% male) healthy young adults. Consistent with predictions, greater reductions in HR variability (HRV) in response to a stressor and greater cortisol output during the study session were associated with shorter relative buccal telomere length (i.e. greater cellular aging). However, the relationship between cortisol output and buccal telomere length became non-significant when adjusting for medication use. Contrary to past findings and study hypotheses, associations between cortisol, blood pressure, and HR reactivity and relative buccal telomere length were not significant. Overall, these findings may indicate there are limited and mixed associations between stress reactivity and telomere length across physiological systems.

  8. The role of feedback information for calibration and attunement in perceiving length by dynamic touch.

    PubMed

    Withagen, Rob; Michaels, Claire F

    2005-12-01

    Two processes have been hypothesized to underlie improvement in perception: attunement and calibration. These processes were examined in a dynamic touch paradigm in which participants were asked to report the lengths of unseen, wielded rods differing in length, diameter, and material. Two experiments addressed whether feedback informs about the need for reattunement and recalibration. Feedback indicating actual length induced both recalibration and reattunement. Recalibration did not occur when feedback indicated only whether 2 rods were of the same length or of different lengths. Such feedback, however, did induce reattunement. These results suggest that attunement and calibration are dissociable processes and that feedback informs which is needed. The observed change in variable use has implications also for research on what mechanical variables underlie length perception by dynamic touch. (c) 2005 APA, all rights reserved.

  9. Accuracy of self-reported length of coma and posttraumatic amnesia in persons with medically verified traumatic brain injury.

    PubMed

    Sherer, Mark; Sander, Angelle M; Maestas, Kacey Little; Pastorek, Nicholas J; Nick, Todd G; Li, Jingyun

    2015-04-01

    To determine the accuracy of self-reported length of coma and posttraumatic amnesia (PTA) in persons with medically verified traumatic brain injury (TBI) and to investigate factors that affect self-report of length of coma and PTA duration. Prospective cohort study. Specialized rehabilitation center with inpatient and outpatient programs. Persons (N=242) with medically verified TBI who were identified from a registry of persons who had previously participated in TBI-related research. Not applicable. Self-reported length of coma and self-reported PTA duration. Review of medical records revealed that the mean medically documented length of coma and PTA duration was 6.9±12 and 19.2±22 days, respectively, and the mean self-reported length of coma and PTA duration was 16.7±22 and 106±194 days, respectively. The average discrepancy between self-report and medical record for length of coma and PTA duration was 8.2±21 and 64±176 days, respectively. Multivariable regression models revealed that time since injury, performance on cognitive tests, and medical record values were associated with self-reported values for both length of coma and PTA duration. In this investigation, persons with medically verified TBI showed poor accuracy in their self-report of length of coma and PTA duration. Discrepancies were large enough to affect injury severity classification. Caution should be exercised when considering self-report of length of coma and PTA duration. Copyright © 2015 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  10. Changing exhumation patterns during Cenozoic growth and glaciation of the Alaska Range: Insights from detrital thermochronology and geochronology

    USGS Publications Warehouse

    Lease, Richard O.; Haeussler, Peter J.; O'Sullivan, Paul

    2016-01-01

    Cenozoic growth of the Alaska Range created the highest topography in North America, but the space-time pattern and drivers of exhumation are poorly constrained. We analyzed U/Pb and fission-track double dates of detrital zircon and apatite grains from 12 catchments that span a 450 km length of the Alaska Range to illuminate the timing and extent of exhumation during different periods. U/Pb ages indicate a dominant Late Cretaceous to Oligocene plutonic provenance for the detrital grains, with only a small percentage of grains recycled from the Mesozoic and Paleozoic sedimentary cover. Fission-track ages record exhumation during Alaska Range growth and incision and reveal three distinctive patterns. First, initial Oligocene exhumation was focused in the central Alaska Range at ~30 Ma and expanded outward along the entire length of the range until 18 Ma. Oligocene exhumation, coeval with initial Yakutat microplate collision >600 km to the southeast, suggests a far-field response to collision that was localized by the Denali Fault within a weak Mesozoic suture zone. Second, the variable timing of middle to late Miocene exhumation suggests independently evolving histories influenced by local structures. Time-transgressive cooling ages suggest successive rock uplift and erosion of Mounts Foraker (12 Ma) through Denali (6 Ma) as crust was advected through a restraining bend in the Denali Fault and indicate a long-term slip rate ~4 mm/yr. Third, Pliocene exhumation is synchronous (3.7–2.7 Ma) along the length of the Alaska Range but only occurs in high-relief, glacier-covered catchments. Pliocene exhumation may record an acceleration in glacial incision that was coincident with the onset of Northern Hemisphere glaciation.

  11. Demographic and clinical characteristics of persons with spinal cord injury in Turkey: One-year experience of a primary referral rehabilitation center.

    PubMed

    Taşoğlu, Özlem; Koyuncu, Engin; Daylak, Rabia; Karacif, Derya Yumuşak; İnce, Zerrin; Yenigün, Didem; Özgirgin, Neşe

    2018-03-01

    To define the demographic and clinical characteristics of persons with spinal cord injury, rehabilitated in a primary referral rehabilitation center in Turkey. Retrospective study. Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey. Medical records of all patients with spinal cord injury (acute-subacute-chronic) at a single academic referral center over the course of one year were reviewed. Variables of each patient were recorded, including: age, sex, etiology, length of rehabilitation stay, neurological level of injury, level of neurological impairment and severity of injury. Among 262 persons with spinal cord injury, 69.8% were male (male:female ratio is 2.31 : 1). Mean age was 38.3 ± 17.6 years. Falls were the most common cause of injury. The majority of falls were falls from a height (93.3%). More than 20% of falls from a height were related to occupational injury. The most common neurological level of injury was L1. Of all persons 46.2% had thoracic, 27.5% had lumbar and 26.3% had cervical lesions. The mean length of rehabilitation stay was 52.1 ± 25.5 days. Persons with motor complete injury and with a shorter (<12 months) time since injury had longer length of rehabilitation stay. The mean age of SCI population is increasing. Falls constitute the majority of etiologic factors and are more common in persons >60 years old. More than 20% of falls from a height are related to occupational injury. Male-female ratio is decreasing. Thoraco-lumbar injures are more common than cervical injuries.

  12. A review of the South American monsoon history as recorded in stable isotopic proxies over the past two millennia

    NASA Astrophysics Data System (ADS)

    Vuille, M.; Burns, S. J.; Taylor, B. L.; Cruz, F. W.; Bird, B. W.; Abbott, M. B.; Kanner, L. C.; Cheng, H.; Novello, V. F.

    2012-08-01

    We review the history of the South American summer monsoon (SASM) over the past ~2000 yr based on high-resolution stable isotope proxies from speleothems, ice cores and lake sediments. Our review is complemented by an analysis of an isotope-enabled atmospheric general circulation model (GCM) for the past 130 yr. Proxy records from the monsoon belt in the tropical Andes and SE Brazil show a very coherent behavior over the past 2 millennia with significant decadal to multidecadal variability superimposed on large excursions during three key periods: the Medieval Climate Anomaly (MCA), the Little Ice Age (LIA) and the current warm period (CWP). We interpret these three periods as times when the SASM's mean state was significantly weakened (MCA and CWP) and strengthened (LIA), respectively. During the LIA each of the proxy archives considered contains the most negative δ18O values recorded during the entire record length. On the other hand, the monsoon strength is currently rather weak in a 2000-yr historical perspective, rivaled only by the low intensity during the MCA. Our climatic interpretation of these archives is consistent with our isotope-based GCM analysis, which suggests that these sites are sensitive recorders of large-scale monsoon variations. We hypothesize that these centennial-scale climate anomalies were at least partially driven by temperature changes in the Northern Hemisphere and in particular over the North Atlantic, leading to a latitudinal displacement of the ITCZ and a change in monsoon intensity (amount of rainfall upstream over the Amazon Basin). This interpretation is supported by several independent records from different proxy archives and modeling studies. Although ENSO is the main forcing for δ18O variability over tropical South America on interannual time scales, our results suggest that its influence may be significantly modulated by North Atlantic climate variability on longer time scales. Finally, our analyses indicate that isotopic proxies, because of their ability to integrate climatic information on large spatial scales, could complement more traditional proxies such as tree rings or documentary evidence. Future climate reconstruction efforts could potentially benefit from including isotopic proxies as large-scale predictors in order to better constrain past changes in the atmospheric circulation.

  13. Auditory observation of stepping actions can cue both spatial and temporal components of gait in Parkinson׳s disease patients.

    PubMed

    Young, William R; Rodger, Matthew W M; Craig, Cathy M

    2014-05-01

    A common behavioural symptom of Parkinson׳s disease (PD) is reduced step length (SL). Whilst sensory cueing strategies can be effective in increasing SL and reducing gait variability, current cueing strategies conveying spatial or temporal information are generally confined to the use of either visual or auditory cue modalities, respectively. We describe a novel cueing strategy using ecologically-valid 'action-related' sounds (footsteps on gravel) that convey both spatial and temporal parameters of a specific action within a single cue. The current study used a real-time imitation task to examine whether PD affects the ability to re-enact changes in spatial characteristics of stepping actions, based solely on auditory information. In a second experimental session, these procedures were repeated using synthesized sounds derived from recordings of the kinetic interactions between the foot and walking surface. A third experimental session examined whether adaptations observed when participants walked to action-sounds were preserved when participants imagined either real recorded or synthesized sounds. Whilst healthy control participants were able to re-enact significant changes in SL in all cue conditions, these adaptations, in conjunction with reduced variability of SL were only observed in the PD group when walking to, or imagining the recorded sounds. The findings show that while recordings of stepping sounds convey action information to allow PD patients to re-enact and imagine spatial characteristics of gait, synthesis of sounds purely from gait kinetics is insufficient to evoke similar changes in behaviour, perhaps indicating that PD patients have a higher threshold to cue sensorimotor resonant responses. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  14. Spatial patterns of fasting and fed antropyloric pressure waves in humans.

    PubMed Central

    Sun, W M; Hebbard, G S; Malbert, C H; Jones, K L; Doran, S; Horowitz, M; Dent, J

    1997-01-01

    1. Gastric mechanics were investigated by categorizing the temporal and spatial patterning of pressure waves associated with individual gastric contractions. 2. In twelve healthy volunteers, intraluminal pressures were monitored from nine side hole recording points spaced at 1.5 cm intervals along the antrum, pylorus and duodenum. 3. Pressure wave sequences that occurred during phase II fasting contractions (n = 221) and after food (n = 778) were evaluated. 4. The most common pattern of pressure wave onset along the antrum was a variable combination of antegrade, synchronous and retrograde propagation between side hole pairs. This variable pattern accounted for 42% of sequences after food, and 34% during fasting (P < 0.05). Other common pressure wave sequence patterns were: purely antegrade-29% after food and 42% during fasting (P < 0.05); purely synchronous-23% fed and 17% fasting; and purely retrograde-6% fed and 8% fasting. The length of sequences was shorter after food (P < 0.05). Some sequences 'skipped' individual recording points. 5. The spatial patterning of gastric pressure wave sequences is diverse, and may explain the differing mechanical outcomes among individual gastric contractions. 6. Better understanding of gastric mechanics may be gained from temporally precise correlations of luminal flows and pressures and gastric wall motion during individual gastric contraction sequences. PMID:9306286

  15. Determining the relationship between sleep architecture, seizure variables and memory in patients with focal epilepsy.

    PubMed

    Miller, Laurie A; Ricci, Monica; van Schalkwijk, Frank J; Mohamed, Armin; van der Werf, Ysbrand D

    2016-06-01

    Sleep has been shown to be important to memory. Both sleep and memory have been found to be abnormal in patients with epilepsy. In this study, we explored the effects that nocturnal epileptiform discharges and the presence of a hippocampal lesion have on sleep patterns and memory. Twenty-five patients with focal epilepsy who underwent a 24-hr ambulatory EEG also completed the Everyday Memory Questionnaire (EMQ). The EEG record was scored for length of time spent in the various sleep stages, time spent awake after sleep onset, and rapid eye movement (REM) latency. Of these sleep variables, only REM latency differed when the epilepsy patients were divided on the bases of either presence/absence of nocturnal discharges or presence/absence of a hippocampal lesion. In both cases, presence of the abnormality was associated with longer latency. Furthermore, longer REM latency was found to be a better predictor of EMQ score than either number of discharges or presence of a hippocampal lesion. Longer REM latency was associated with a smaller percentage of time spent in slow-wave sleep in the early part of the night and may serve as a particularly sensitive marker to disturbances in sleep architecture. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  16. Periodic Overload and Transport Spectrum Fatigue Crack Growth Tests of Ti62222STA and Al2024T3 Sheet

    NASA Technical Reports Server (NTRS)

    Phillips, Edward P.

    1999-01-01

    Variable amplitude loading crack growth tests have been conducted to provide data that can be used to evaluate crack growth prediction codes. Tests with periodic overloads or overloads followed by underloads were conducted on titanium alloy Ti-6Al-2Sn-2Zr-2Mo-2Cr solution treated and aged (Ti62222STA) material at room temperature and at 350 F. Spectrum fatigue crack growth tests were conducted on two materials (Ti62222STA and aluminum alloy 2024-T3) using two transport lower-wing test spectra at two temperatures (room temperature and 350 F (Ti only)). Test lives (growth from an initial crack half-length of 0.15 in. to failure) were recorded in all tests and the crack length against cycles (or flights) data were recorded in many of the tests. The following observations were made regarding the test results: (1) in tests of the Ti62222STA material, the tests at 350 F had longer lives than those at room temperature, (2) in tests to the MiniTwist spectrum, the Al2024T3 material showed much greater crack growth retardations due to the highest stresses in the spectrum than did the Ti62222STA material, and (3) comparisons of material crack growth performances on an "equal weight" basis were spectrum dependent.

  17. Are maturation, growth and lower extremity alignment associated with overuse injury in elite adolescent ballet dancers?

    PubMed

    Bowerman, Erin; Whatman, Chris; Harris, Nigel; Bradshaw, Elizabeth; Karin, Janet

    2014-11-01

    To identify growth, maturation and biomechanical risk factors for overuse injury in elite adolescent ballet dancers. Maturation (Tanner scale), growth (foot length change) and age at onset of menarche were recorded in elite adolescent ballet dancers. A modified knee valgus angle and lateral tilt of the pelvis were measured using 2D video during two dance movements (fondu, temps levé) to quantify lower extremity alignment. Overuse dance injuries were recorded by a physiotherapist. The injury rate ratio (RR) associated with each variable was estimated using over-dispersed Poisson regression modelling. Changes in right foot length (RR = 1.41, CI = 0.93-2.13), right knee angles during the fondu (RR = 0.68, CI = 0.45-1.03) and temps levé (RR = 0.72, CI = 0.53-0.98), and pelvic angles during the temps levé on the left (RR = 0.52, CI = 0.30-0.90) and fondu on the right (RR = 1.28, CI = 0.91-1.80) were associated with substantial changes in injury risk. Rate of growth in elite adolescent ballet dancers is likely associated with an increase in risk of lower extremity overuse injury and better right lower extremity alignment is likely associated with a reduction in risk of right lower extremity overuse injury. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. Sarcomere Length and Tension Changes in Tetanized Frog Muscle Fibers after Quick Stretches and Releases

    NASA Astrophysics Data System (ADS)

    Sugi, Haruo; Kobayashi, Takakazu

    1983-10-01

    The sarcomere length changes in tetanized frog muscle fibers in response to quick fiber length changes were examined along the fiber length with a high-sensitivity laser diffraction technique. The experiments were only performed with muscle fibers in which the uniform orientation and sarcomere length of the component myofibrils were well preserved during a tetanus. When the sarcomere length changes were recorded near the fixed fiber end, the delay of the onset of sarcomere length change in response to the applied fiber length change tended to be longer than that of the onset of tension changes recorded at the fixed fiber end. The magnitude of sarcomere length changes was larger near the moving fiber end than near the fixed fiber end. In the case of quick releases, the resulting sarcomere shortening tended to outlast the fiber shortening, so that the quick tension recovery started during the sarcomere shortening. These results indicate (i) that the tension changes in response to quick fiber length changes may not give direct information about the cross-bridge properties and (ii) that the viscoelastic multisegmental nature of muscle fibers should be taken into consideration in interpreting the tension responses to quick length changes.

  19. Predictive value of magnetic resonance imaging determined tumor contact length for extracapsular extension of prostate cancer.

    PubMed

    Baco, Eduard; Rud, Erik; Vlatkovic, Ljiljana; Svindland, Aud; Eggesbø, Heidi B; Hung, Andrew J; Matsugasumi, Toru; Bernhard, Jean-Christophe; Gill, Inderbir S; Ukimura, Osamu

    2015-02-01

    Tumor contact length is defined as the amount of prostate cancer in contact with the prostatic capsule. We evaluated the ability of magnetic resonance imaging determined tumor contact length to predict microscopic extracapsular extension compared to existing predictors of extracapsular extension. We retrospectively analyzed the records of 111 consecutive patients with magnetic resonance imaging/ultrasound fusion targeted, biopsy proven prostate cancer who underwent radical prostatectomy from January 2010 to July 2013. Median patient age was 64 years and median prostate specific antigen was 8.9 ng/ml. Clinical stage was cT1 in 93 cases (84%) and cT2 in 18 (16%). Postoperative pathological analysis confirmed pT2 in 71 patients (64%) and pT3 in 40 (36%). We evaluated 1) in the radical prostatectomy specimen the correlation of microscopic extracapsular extension with pathological cancer volume, pathological tumor contact length and Gleason score, 2) the correlation between microscopic extracapsular extension and magnetic resonance imaging tumor contact length, and 3) the ability of preoperative variables to predict microscopic extracapsular extension. Logistic regression analysis revealed that pathological tumor contact length correlated better with microscopic extracapsular extension than the predictive power of pathological cancer volume (0.821 vs 0.685). The Spearman correlation between pathological and magnetic resonance imaging tumor contact length was r = 0.839 (p <0.0001). ROC AUC analysis revealed that magnetic resonance imaging tumor contact length outperformed cancer core involvement on targeted biopsy and the Partin tables to predict microscopic extracapsular extension (0.88 vs 0.70 and 0.63, respectively). At a magnetic resonance imaging tumor contact length threshold of 20 mm the accuracy for diagnosing microscopic extracapsular extension was superior to that of conventional magnetic resonance imaging criteria (82% vs 67%, p = 0.015). We developed a predicted probability plot curve of extracapsular extension according to magnetic resonance imaging tumor contact length. Magnetic resonance imaging determined tumor contact length could be a promising quantitative predictor of microscopic extracapsular extension. Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  20. Obstetric determinants of neonatal survival: antenatal predictors of neonatal survival and morbidity in extremely low birth weight infants.

    PubMed

    Bottoms, S F; Paul, R H; Mercer, B M; MacPherson, C A; Caritis, S N; Moawad, A H; Van Dorsten, J P; Hauth, J C; Thurnau, G R; Miodovnik, M; Meis, P M; Roberts, J M; McNellis, D; Iams, J D

    1999-03-01

    The aim of the study was to compare clinical and ultrasonographic variables obtained before delivery as predictors of neonatal survival and morbidity in infants weighing

  1. Implementation and evaluation of a clinical pathway for TRAM breast reconstruction.

    PubMed

    Hwang, T G; Wilkins, E G; Lowery, J C; Gentile, J

    2000-02-01

    Among strategies recently proposed to reduce practice variation, promote quality, and control costs in health care delivery, the concept of the clinical pathway has received considerable attention. Because transverse rectus abdominis musculocutaneous (TRAM) breast reconstruction is a common and often costly intervention, this institution sought to evaluate cost and quality outcomes of a clinical pathways program for this procedure. The TRAM reconstruction clinical pathway was implemented in April of 1996 to standardize postoperative care in this patient population. Outcomes of consecutive pathway cases for the first 14 months of the program were assessed in a retrospective cohort design, by using all nonpathway TRAM cases from the 18 months immediately before pathway implementation as controls. Outcomes assessed included length of hospital stay, postoperative complications, total postoperative charges, and total postoperative costs in relative value units. Data on these dependent variables were collected from hospital charts and billing records. The effects of pathway implementation on the outcomes of interest were analyzed by using analysis of covariance to control for potential confounding by other independent variables, including surgical site (unilateral versus bilateral reconstructions), technique (pedicle versus free TRAMs), timing (immediate versus delayed reconstructions), and patient age. Finally, a comparison of variances in the outcomes of interest between the two groups was analyzed by using an Ftest. For all statistical tests, p values of < or = 0.05 were considered significant. Twenty-nine patients were treated in the TRAM pathway group, whereas the control population included 40 nonpathway patients. After implementation of the TRAM pathway, length of stay decreased from 6.0 to 5.2 days; total postoperative charges were reduced from $8587 to $7744; and total postoperative relative value unit utilization declined from 1686 to 1104. Analysis of covariance showed that the decreases in length of hospital stay and relative value units in the TRAM pathway were statistically significant (p = 0.05 and p = 0.007, respectively). By contrast, no significant increase in complications was observed after pathway implementation. Variability in the TRAM pathway group, as measured by SD, decreased significantly for both length of hospital stay (p = 0.039) and relative value units (p = 0.023). Implementation of the TRAM reconstruction clinical pathway resulted in significant declines in length of hospital stay and total costs. These decreases in resource utilization had no significant effect on postoperative complication rates. Although additional research is needed to further assess the impact of clinical pathways, this approach offers considerable promise for improving the cost-effectiveness of health care.

  2. Length and sequence variability in mitochondrial control region of the milkfish, Chanos chanos.

    PubMed

    Ravago, Rachel G; Monje, Virginia D; Juinio-Meñez, Marie Antonette

    2002-01-01

    Extensive length variability was observed in the mitochondrial control region of the milkfish, Chanos chanos. The nucleotide sequence of the control region and flanking regions was determined. Length variability and heteroplasmy was due to the presence of varying numbers of a 41-bp tandemly repeated sequence and a 48-bp insertion/deletion (indel). The structure and organization of the milkfish control region is similar to that of other teleost fish and vertebrates. However, extensive variation in the copy number of tandem repeats (4-20 copies) and the presence of a relatively large (48-bp) indel, are apparently uncommon in teleost fish control region sequences reported to date. High sequence variability of control region peripheral domains indicates the potential utility of selected regions as markers for population-level studies.

  3. Beat-to-Beat Variability of Ventricular Action Potential Duration Oscillates at Low Frequency During Sympathetic Provocation in Humans

    PubMed Central

    Porter, Bradley; van Duijvenboden, Stefan; Bishop, Martin J.; Orini, Michele; Claridge, Simon; Gould, Justin; Sieniewicz, Benjamin J.; Sidhu, Baldeep; Razavi, Reza; Rinaldi, Christopher A.; Gill, Jaswinder S.; Taggart, Peter

    2018-01-01

    Background: The temporal pattern of ventricular repolarization is of critical importance in arrhythmogenesis. Enhanced beat-to-beat variability (BBV) of ventricular action potential duration (APD) is pro-arrhythmic and is increased during sympathetic provocation. Since sympathetic nerve activity characteristically exhibits burst patterning in the low frequency range, we hypothesized that physiologically enhanced sympathetic activity may not only increase BBV of left ventricular APD but also impose a low frequency oscillation which further increases repolarization instability in humans. Methods and Results: Heart failure patients with cardiac resynchronization therapy defibrillator devices (n = 11) had activation recovery intervals (ARI, surrogate for APD) recorded from left ventricular epicardial electrodes alongside simultaneous non-invasive blood pressure and respiratory recordings. Fixed cycle length was achieved by right ventricular pacing. Recordings took place during resting conditions and following an autonomic stimulus (Valsalva). The variability of ARI and the normalized variability of ARI showed significant increases post Valsalva when compared to control (p = 0.019 and p = 0.032, respectively). The oscillatory behavior was quantified by spectral analysis. Significant increases in low frequency (LF) power (p = 0.002) and normalized LF power (p = 0.019) of ARI were seen following Valsalva. The Valsalva did not induce changes in conduction variability nor the LF oscillatory behavior of conduction. However, increases in the LF power of ARI were accompanied by increases in the LF power of systolic blood pressure (SBP) and the rate of systolic pressure increase (dP/dtmax). Positive correlations were found between LF-SBP and LF-dP/dtmax (rs = 0.933, p < 0.001), LF-ARI and LF-SBP (rs = 0.681, p = 0.001) and between LF-ARI and LF-dP/dtmax (rs = 0.623, p = 0.004). There was a strong positive correlation between the variability of ARI and LF power of ARI (rs = 0.679, p < 0.001). Conclusions: In heart failure patients, physiological sympathetic provocation induced low frequency oscillation (~0.1 Hz) of left ventricular APD with a strong positive correlation between the LF power of APD and the BBV of APD. These findings may be of importance in mechanisms underlying stability/instability of repolarization and arrhythmogenesis in humans. PMID:29670531

  4. Structures of the Recurrence Plot of Heart Rate Variability Signal as a Tool for Predicting the Onset of Paroxysmal Atrial Fibrillation

    PubMed Central

    Mohebbi, Maryam; Ghassemian, Hassan; Asl, Babak Mohammadzadeh

    2011-01-01

    This paper aims to propose an effective paroxysmal atrial fibrillation (PAF) predictor which is based on the analysis of the heart rate variability (HRV) signal. Predicting the onset of PAF, based on non-invasive techniques, is clinically important and can be invaluable in order to avoid useless therapeutic interventions and to minimize the risks for the patients. This method consists of four steps: Preprocessing, feature extraction, feature reduction, and classification. In the first step, the QRS complexes are detected from the electrocardiogram (ECG) signal and then the HRV signal is extracted. In the next step, the recurrence plot (RP) of HRV signal is obtained and six features are extracted to characterize the basic patterns of the RP. These features consist of length of longest diagonal segments, average length of the diagonal lines, entropy, trapping time, length of longest vertical line, and recurrence trend. In the third step, these features are reduced to three features by the linear discriminant analysis (LDA) technique. Using LDA not only reduces the number of the input features, but also increases the classification accuracy by selecting the most discriminating features. Finally, a support vector machine-based classifier is used to classify the HRV signals. The performance of the proposed method in prediction of PAF episodes was evaluated using the Atrial Fibrillation Prediction Database which consists of both 30-minutes ECG recordings end just prior to the onset of PAF and segments at least 45 min distant from any PAF events. The obtained sensitivity, specificity, and positive predictivity were 96.55%, 100%, and 100%, respectively. PMID:22606666

  5. ANALYSIS OF SURGICAL SITE INFECTIONS IN PEDIATRIC PATIENTS AFTER ORTHOPEDIC SURGERY: A CASE-CONTROL STUDY

    PubMed Central

    Chagas, Mariana de Queiroz Leite; Costa, Ana Maria Magalhães; Mendes, Pedro Henrique Barros; Gomes, Saint Clair

    2017-01-01

    ABSTRACT Objectives: To describe the rate of surgical site infections in children undergoing orthopedic surgery in centers of excellence and analyze the patients’ profiles. Methods: Medical records of pediatric patients undergoing orthopedic surgery in the Jamil Haddad National Institute of Traumatology and Orthopedics from January 2012 to December 2013 were analyzed and monitored for one year. Patients diagnosed with surgical site infection were matched with patients without infection by age, date of admission, field of orthopedic surgery and type of surgical procedure. Patient, surgical and follow-up variables were examined. Descriptive, bivariate and correspondence analyses were performed to evaluate the patients’ profiles. Results: 347 surgeries and 10 surgical site infections (2.88%) were identified. There was association of infections with age - odds ratio (OR) 11.5 (confidence interval - 95%CI 1.41-94.9) -, implant - OR 7.3 (95%CI 1.46-36.3) -, preoperative period - OR 9.8 (95%CI 1.83-53.0), and length of hospitalization - OR 20.6 (95%CI 3.7-114.2). The correspondence analysis correlated the infection and preoperative period, weight, weight Z-score, age, implant, type of surgical procedure, and length of hospitalization. Average time to diagnosis of infection occurred 26.5±111.46 days after surgery. Conclusions: The rate of surgical site infection was 2.88%, while higher in children over 24 months of age who underwent surgical implant procedures and had longer preoperative periods and lengths of hospitalization. This study identified variables for the epidemiological surveillance of these events in children. Available databases and appropriate analysis methods are essential to monitor and improve the quality of care offered to the pediatric population. PMID:28977312

  6. On the Existence of Step-To-Step Breakpoint Transitions in Accelerated Sprinting

    PubMed Central

    McGhie, David; Danielsen, Jørgen; Sandbakk, Øyvind; Haugen, Thomas

    2016-01-01

    Accelerated running is characterised by a continuous change of kinematics from one step to the next. It has been argued that breakpoints in the step-to-step transitions may occur, and that these breakpoints are an essential characteristic of dynamics during accelerated running. We examined this notion by comparing a continuous exponential curve fit (indicating continuity, i.e., smooth transitions) with linear piecewise fitting (indicating breakpoint). We recorded the kinematics of 24 well trained sprinters during a 25 m sprint run with start from competition starting blocks. Kinematic data were collected for 24 anatomical landmarks in 3D, and the location of centre of mass (CoM) was calculated from this data set. The step-to-step development of seven variables (four related to CoM position, and ground contact time, aerial time and step length) were analysed by curve fitting. In most individual sprints (in total, 41 sprints were successfully recorded) no breakpoints were identified for the variables investigated. However, for the mean results (i.e., the mean curve for all athletes) breakpoints were identified for the development of vertical CoM position, angle of acceleration and distance between support surface and CoM. It must be noted that for these variables the exponential fit showed high correlations (r2>0.99). No relationship was found between the occurrences of breakpoints for different variables as investigated using odds ratios (Mantel-Haenszel Chi-square statistic). It is concluded that although breakpoints regularly appear during accelerated running, these are not the rule and thereby unlikely a fundamental characteristic, but more likely an expression of imperfection of performance. PMID:27467387

  7. Variable-Period Undulators For Synchrotron Radiation

    DOEpatents

    Shenoy, Gopal; Lewellen, John; Shu, Deming; Vinokurov, Nikolai

    2005-02-22

    A new and improved undulator design is provided that enables a variable period length for the production of synchrotron radiation from both medium-energy and high-energy storage rings. The variable period length is achieved using a staggered array of pole pieces made up of high permeability material, permanent magnet material, or an electromagnetic structure. The pole pieces are separated by a variable width space. The sum of the variable width space and the pole width would therefore define the period of the undulator. Features and advantages of the invention include broad photon energy tunability, constant power operation and constant brilliance operation.

  8. Influence of clinical baseline findings on the survival of 2 post systems: a randomized clinical trial.

    PubMed

    Schmitter, Marc; Rammelsberg, Peter; Gabbert, Olaf; Ohlmann, Brigitte

    2007-01-01

    The aim of this prospective randomized controlled trial was to evaluate the influence of clinical baseline characteristics on the survival of 2 post systems. One hundred patients needing a post were included. Half the patients received a glass fiber-reinforced post (FRP), and the other half received metal screw posts (MSP). The posts were assigned randomly. In addition to demographic data, the following parameters were recorded: type of tooth (incisor/canine versus molar/premolar), length of the post in relation to root length (percentage), extent of coronal tooth destruction (percentage), ferrule height (in millimeters), type of restoration (fixed or removable partial denture), and presence of antagonistic contacts (yes/no). After at least 1 year (mean: 13.84 months), the patients were recalled. Statistical analysis was performed using the log-rank test and Cox regression analysis. The survival rate of FRPs was 93.5%. In the MSP group, the survival rate was significantly lower (75.6%; log-rank test, P = .049). Additionally, the metal posts were associated with more unfavorable complications, for example, root fracture. The type of the tooth and the degree of coronal tooth destruction influenced the survival of MSPs, whereas no influence of these variables could be seen for FRPs. FRPs are superior to MSPs with respect to short-term clinical performance. Especially for MSPs, clinical survival depends on several variables.

  9. A comparison of daily water use estimates derived from constant-heat sap-flow probe values and gravimetric measurements in pot-grown saplings.

    PubMed

    McCulloh, Katherine A; Winter, Klaus; Meinzer, Frederick C; Garcia, Milton; Aranda, Jorge; Lachenbruch, Barbara

    2007-09-01

    Use of Granier-style heat dissipation sensors to measure sap flow is common in plant physiology, ecology and hydrology. There has been concern that any change to the original Granier design invalidates the empirical relationship between sap flux density and the temperature difference between the probes. Here, we compared daily water use estimates from gravimetric measurements with values from variable length heat dissipation sensors, which are a relatively new design. Values recorded during a one-week period were compared for three large pot-grown saplings of each of the tropical trees Pseudobombax septenatum (Jacq.) Dugand and Calophyllum longifolium Willd. For five of the six individuals, P values from paired t-tests comparing the two methods ranged from 0.12 to 0.43 and differences in estimates of total daily water use over the week of the experiment averaged < 3%. In one P. septenatum sapling, the sap flow sensors underestimated water use relative to the gravimetric measurements. This discrepancy could have been associated with naturally occurring gradients in temperature that reduced the difference in temperature between the probes, which would have caused the sensor method to underestimate water use. Our results indicate that substitution of variable length heat dissipation probes for probes of the original Granier design did not invalidate the empirical relationship determined by Granier between sap flux density and the temperature difference between probes.

  10. Retrograde nailing for distal third femoral shaft fractures: a prospective study.

    PubMed

    Acharya, K N; Rao, M R

    2006-12-01

    To evaluate the postoperative knee function and results of unreamed retrograde nailing for distal third femoral shaft fractures. Between January 2002 and 2003 inclusive, a consecutive series of 27 patients (with 28 fractures) who underwent retrograde nailing were prospectively evaluated. Outcome measures were union time, initiation of weight bearing, deformity and shortening, functional length of the nail, knee function assessed using a modified Knee Society Knee Score. Correlations between union time and other variables were also studied. In these patients 26 (93%) of the 28 fractures achieved union, of which 5 underwent dynamisation; the mean union time for the other 21 fractures was 4.4 months. Angular malalignment was present in 4 patients and shortening in 4 others. There was negligible correlation between union time and variables of nail-canal diameter mismatch, functional length of nail, fracture geometry, or initiation of partial weight bearing ambulation. Knee flexion of more than 100 degrees was achieved in 26 patients. 19 patients had anterior knee pain and 10 had instability. By the end of one year, excellent or good scores for pain and function were recorded in 77% and 73% respectively, of the 26 patients. In view of such favourable union rates but significant deterioration in overall knee joint function, at best retrograde nailing is a reliable alternative in the management of selected complicated fractures of the distal femoral shaft.

  11. Variability and trends in dry day frequency and dry event length in the southwestern United States

    USGS Publications Warehouse

    McCabe, Gregory J.; Legates, David R.; Lins, Harry F.

    2010-01-01

    Daily precipitation from 22 National Weather Service first-order weather stations in the southwestern United States for water years 1951 through 2006 are used to examine variability and trends in the frequency of dry days and dry event length. Dry events with minimum thresholds of 10 and 20 consecutive days of precipitation with less than 2.54 mm are analyzed. For water years and cool seasons (October through March), most sites indicate negative trends in dry event length (i.e., dry event durations are becoming shorter). For the warm season (April through September), most sites also indicate negative trends; however, more sites indicate positive trends in dry event length for the warm season than for water years or cool seasons. The larger number of sites indicating positive trends in dry event length during the warm season is due to a series of dry warm seasons near the end of the 20th century and the beginning of the 21st century. Overall, a large portion of the variability in dry event length is attributable to variability of the El Niño–Southern Oscillation, especially for water years and cool seasons. Our results are consistent with analyses of trends in discharge for sites in the southwestern United States, an increased frequency in El Niño events, and positive trends in precipitation in the southwestern United States.

  12. Within-Event and Between-Events Ground Motion Variability from Earthquake Rupture Scenarios

    NASA Astrophysics Data System (ADS)

    Crempien, Jorge G. F.; Archuleta, Ralph J.

    2017-09-01

    Measurement of ground motion variability is essential to estimate seismic hazard. Over-estimation of variability can lead to extremely high annual hazard estimates of ground motion exceedance. We explore different parameters that affect the variability of ground motion such as the spatial correlations of kinematic rupture parameters on a finite fault and the corner frequency of the moment-rate spectra. To quantify the variability of ground motion, we simulate kinematic rupture scenarios on several vertical strike-slip faults and compute ground motion using the representation theorem. In particular, for the entire suite of rupture scenarios, we quantify the within-event and the between-events ground motion variability of peak ground acceleration (PGA) and response spectra at several periods, at 40 stations—all approximately at an equal distance of 20 and 50 km from the fault. Both within-event and between-events ground motion variability increase when the slip correlation length on the fault increases. The probability density functions of ground motion tend to truncate at a finite value when the correlation length of slip decreases on the fault, therefore, we do not observe any long-tail distribution of peak ground acceleration when performing several rupture simulations for small correlation lengths. Finally, for a correlation length of 6 km, the within-event and between-events PGA log-normal standard deviations are 0.58 and 0.19, respectively, values slightly smaller than those reported by Boore et al. (Earthq Spectra, 30(3):1057-1085, 2014). The between-events standard deviation is consistently smaller than the within-event for all correlations lengths, a feature that agrees with recent ground motion prediction equations.

  13. Postsacral vertebral morphology in relation to tail length among primates and other mammals.

    PubMed

    Russo, Gabrielle A

    2015-02-01

    Tail reduction/loss independently evolved in a number of mammalian lineages, including hominoid primates. One prerequisite to appropriately contextualizing its occurrence and understanding its significance is the ability to track evolutionary changes in tail length throughout the fossil record. However, to date, the bony correlates of tail length variation among living taxa have not been comprehensively examined. This study quantifies postsacral vertebral morphology among living primates and other mammals known to differ in relative tail length (RTL). Linear and angular measurements with known biomechanical significance were collected on the first, mid-, and transition proximal postsacral vertebrae, and their relationship with RTL was assessed using phylogenetic generalized least-squares regression methods. Compared to shorter-tailed primates, longer-tailed primates possess a greater number of postsacral vertebral features associated with increased proximal tail flexibility (e.g., craniocaudally longer vertebral bodies), increased intervertebral body joint range of motion (e.g., more circularly shaped cranial articular surfaces), and increased leverage of tail musculature (e.g., longer spinous processes). These observations are corroborated by the comparative mammalian sample, which shows that distantly related short-tailed (e.g., Phascolarctos, Lynx) and long-tailed (e.g., Dendrolagus, Acinonyx) nonprimate mammals morphologically converge with short-tailed (e.g., Macaca tonkeana) and long-tailed (e.g., Macaca fascicularis) primates, respectively. Multivariate models demonstrate that the variables examined account for 70% (all mammals) to 94% (only primates) of the variance in RTL. Results of this study may be used to infer the tail lengths of extinct primates and other mammals, thereby improving our understanding about the evolution of tail reduction/loss. © 2014 Wiley Periodicals, Inc.

  14. A combined morphometric analysis of foot form and its association with sex, stature, and body mass.

    PubMed

    Domjanic, Jacqueline; Seidler, Horst; Mitteroecker, Philipp

    2015-08-01

    Morphometric analysis of footprints is a classic means for orthopedic diagnosis. In forensics and physical anthropology, it is commonly used for the estimation of stature and body mass. We studied individual variation and sexual dimorphism of foot dimensions and footprint shape by a combination of classic foot measurements and geometric morphometric methods. Left and right feet of 134 healthy adult males and females were scanned twice with a 3D optical laser scanner, and stature as well as body mass were recorded. Foot length and width were measured on the 3D scans. The 2D footprints were extracted as the plantar-most 2 mm of the 3D scans and measured with 85 landmarks and semilandmarks. Both foot size and footprint shape are sexually dimorphic and relate to stature and body mass. While dimorphism in foot length largely results from dimorphism in stature, dimorphism in footprint shape partly owes to the dimorphism in BMI. Stature could be estimated well based on foot length (R(2)  = 0.76), whereas body mass was more closely related to foot width (R(2)  = 0.62). Sex could be estimated correctly for 95% of the individuals based on a combination of foot width and length. Geometric morphometrics proved to be an effective tool for the detailed analysis of footprint shape. However, for the estimation of stature, body mass, and sex, shape variables did not considerably improve estimates based on foot length and width. © 2015 Wiley Periodicals, Inc.

  15. Evaluation of the relation between triceps surae H-reflex, M-response latencies and thigh length in normal population.

    PubMed

    Khosrawi, Saeid; Fallah, Salman

    2013-03-01

    The H-reflex is a useful electrophysiological procedure for evaluating the status of the peripheral nervous system, especially at the proximal segment of the peripheral nerve. The purpose of this study is to investigate the relation between triceps surae H-reflex and M- response latencies and thigh length in normal population, in order to determine if there is any regression equation between them. After screening 75 volunteers by considering inclusion and exclusion criteria, 72 of them were selected to enroll into our study (34 men and 38 women with the mean age of 36.04 ± 7.7 years). In all of the subjects H-reflex and M-response latencies were recorded by standard electrophysiological techniques and thigh length was measured. Finally, our data was analyzed for its relations with respect to ages in both sexes by appropriate statistical and mathematical methods. Mean ± SD for H-reflex latency was 27.94 ± 1.6 ms. We found a significant correlation between H-reflex latency and M-latency (r = 0.28), no significant correlation was found between H-reflex latency and thigh length (r = -0.051). Finally based on our findings we introduce a new formula in this paper. We found a significant correlation among of M-response latency and other variables (H-reflex latency and thigh length). Despite this it was eliminated from our formula. The relationship between H-reflex latency and age was significant. Further studies are required to delineate the clinical usage and interpretation of the formula, which we found in this study.

  16. Effect of early realignment on length and delayed repair of postpelvic fracture urethral injury.

    PubMed

    Koraitim, Mamdouh M

    2012-04-01

    To determine the effect of early realignment of posterior urethral injury on the length and delayed repair of ensuing urethral defect. We reviewed the medical records of 120 patients with a pelvic fracture urethral defect who were referred for delayed repair from elsewhere from 1995 to 2009. The review was focused on 5 variables: initial management of urethral injury, length of urethral defect, type of delayed repair, continence, and erectile function. Of the patients, 26 were excluded from the study and 94 were categorized as having been initially treated by realignment (42 patients, group 1) or suprapubic cystostomy (52 patients, group 2). Urethral defects ≤ 2 cm in length were found in 28 patients (67%) in group 1 versus 22 (42%) in group 2. Defects >2 cm were found in 14 patients (33%) in group 1 versus 30 (58%) in group 2. The repair was accomplished by a simple perineal operation in 32 (76%) and 30 (58%) patients in groups 1 and 2, respectively. An elaborated perineal or perineo-abdominal procedure was required in 10 (24%) and 22 (42%) patients in groups 1 and 2, respectively (all P < .05). Incontinence occurred in 1 patient in group 1. Impotence developed in 10 (28%) of 36 realigned adults and in 2 (5%) of 38 adults with suprapubic cystostomy. Early realignment of posterior urethral injury decreases the length of the ensuing urethral defect and facilitates its delayed repair. Incontinence and impotence appear to result from the injury itself and not the treatment. Copyright © 2012 Elsevier Inc. All rights reserved.

  17. Improved theory of time domain reflectometry with variable coaxial cable length for electrical conductivity measurements

    USDA-ARS?s Scientific Manuscript database

    Although empirical models have been developed previously, a mechanistic model is needed for estimating electrical conductivity (EC) using time domain reflectometry (TDR) with variable lengths of coaxial cable. The goals of this study are to: (1) derive a mechanistic model based on multisection tra...

  18. Do diagnosis-related groups appropriately explain variations in costs and length of stay of hip replacement? A comparative assessment of DRG systems across 10 European countries.

    PubMed

    Geissler, Alexander; Scheller-Kreinsen, David; Quentin, Wilm

    2012-08-01

    This paper assesses the variations in costs and length of stay for hip replacement cases in Austria, England, Estonia, Finland, France, Germany, Ireland, Poland, Spain and Sweden and examines the ability of national diagnosis-related group (DRG) systems to explain the variation in resource use against a set of patient characteristic and treatment specific variables. In total, 195,810 cases clustered in 712 hospitals were analyzed using OLS fixed effects models for cost data (n=125,698) and negative binominal models for length-of-stay data (n=70,112). The number of DRGs differs widely across the 10 European countries (range: 2-14). Underlying this wide range is a different use of classification variables, especially secondary diagnoses and treatment options are considered to a different extent. In six countries, a standard set of patient characteristics and treatment variables explain the variation in costs or length of stay better than the DRG variables. This raises questions about the adequacy of the countries' DRG system or the lack of specific criteria, which could be used as classification variables. Copyright © 2012 John Wiley & Sons, Ltd.

  19. Association of Day Length and Weather Conditions with Physical Activity Levels in Older Community Dwelling People

    PubMed Central

    Witham, Miles D.; Donnan, Peter T.; Vadiveloo, Thenmalar; Sniehotta, Falko F.; Crombie, Iain K.; Feng, Zhiqiang; McMurdo, Marion E. T.

    2014-01-01

    Background Weather is a potentially important determinant of physical activity. Little work has been done examining the relationship between weather and physical activity, and potential modifiers of any relationship in older people. We therefore examined the relationship between weather and physical activity in a cohort of older community-dwelling people. Methods We analysed prospectively collected cross-sectional activity data from community-dwelling people aged 65 and over in the Physical Activity Cohort Scotland. We correlated seven day triaxial accelerometry data with daily weather data (temperature, day length, sunshine, snow, rain), and a series of potential effect modifiers were tested in mixed models: environmental variables (urban vs rural dwelling, percentage of green space), psychological variables (anxiety, depression, perceived behavioural control), social variables (number of close contacts) and health status measured using the SF-36 questionnaire. Results 547 participants, mean age 78.5 years, were included in this analysis. Higher minimum daily temperature and longer day length were associated with higher activity levels; these associations remained robust to adjustment for other significant associates of activity: age, perceived behavioural control, number of social contacts and physical function. Of the potential effect modifier variables, only urban vs rural dwelling and the SF-36 measure of social functioning enhanced the association between day length and activity; no variable modified the association between minimum temperature and activity. Conclusions In older community dwelling people, minimum temperature and day length were associated with objectively measured activity. There was little evidence for moderation of these associations through potentially modifiable health, environmental, social or psychological variables. PMID:24497925

  20. Association of day length and weather conditions with physical activity levels in older community dwelling people.

    PubMed

    Witham, Miles D; Donnan, Peter T; Vadiveloo, Thenmalar; Sniehotta, Falko F; Crombie, Iain K; Feng, Zhiqiang; McMurdo, Marion E T

    2014-01-01

    Weather is a potentially important determinant of physical activity. Little work has been done examining the relationship between weather and physical activity, and potential modifiers of any relationship in older people. We therefore examined the relationship between weather and physical activity in a cohort of older community-dwelling people. We analysed prospectively collected cross-sectional activity data from community-dwelling people aged 65 and over in the Physical Activity Cohort Scotland. We correlated seven day triaxial accelerometry data with daily weather data (temperature, day length, sunshine, snow, rain), and a series of potential effect modifiers were tested in mixed models: environmental variables (urban vs rural dwelling, percentage of green space), psychological variables (anxiety, depression, perceived behavioural control), social variables (number of close contacts) and health status measured using the SF-36 questionnaire. 547 participants, mean age 78.5 years, were included in this analysis. Higher minimum daily temperature and longer day length were associated with higher activity levels; these associations remained robust to adjustment for other significant associates of activity: age, perceived behavioural control, number of social contacts and physical function. Of the potential effect modifier variables, only urban vs rural dwelling and the SF-36 measure of social functioning enhanced the association between day length and activity; no variable modified the association between minimum temperature and activity. In older community dwelling people, minimum temperature and day length were associated with objectively measured activity. There was little evidence for moderation of these associations through potentially modifiable health, environmental, social or psychological variables.

  1. The Dust Storm Index (DSI): A method for monitoring broadscale wind erosion using meteorological records

    NASA Astrophysics Data System (ADS)

    O'Loingsigh, T.; McTainsh, G. H.; Tews, E. K.; Strong, C. L.; Leys, J. F.; Shinkfield, P.; Tapper, N. J.

    2014-03-01

    Wind erosion of soils is a natural process that has shaped the semi-arid and arid landscapes for millennia. This paper describes the Dust Storm Index (DSI); a methodology for monitoring wind erosion using Australian Bureau of Meteorology (ABM) meteorological observational data since the mid-1960s (long-term), at continental scale. While the 46 year length of the DSI record is its greatest strength from a wind erosion monitoring perspective, there are a number of technical challenges to its use because when the World Meteorological Organisation (WMO) recording protocols were established the use of the data for wind erosion monitoring was never intended. Data recording and storage protocols are examined, including the effects of changes to the definition of how observers should interpret and record dust events. A method is described for selecting the 180 long-term ABM stations used in this study and the limitations of variable observation frequencies between stations are in part resolved. The rationale behind the DSI equation is explained and the examples of temporal and spatial data visualisation products presented include; a long term national wind erosion record (1965-2011), continental DSI maps, and maps of the erosion event types that are factored into the DSI equation. The DSI is tested against dust concentration data and found to provide an accurate representation of wind erosion activity. As the ABM observational records used here were collected according to WMO protocols, the DSI methodology could be used in all countries with WMO-compatible meteorological observation and recording systems.

  2. The Remarkable Change in Euro-American Cranial Shape and Size.

    PubMed

    Jantz, Richard L; Jantz, Lee Meadows

    2016-01-01

    Secular changes in stature, weight, or other components of the body that can be obtained from historical records have been extensively studied. Cranial change has been central to anthropology for more than a century, but the focus has normally been on change measured in centuries or millennia. Cranial change measured in decades, normally considered to result from plastic response to the environment, has been less studied. This article reports on change in cranial vault dimensions in white Americans. Variables were glabello-occipital length (GOL), basion-bregma height (BBH), basion-nasion length (BNL), maximum cranial breadth (XCB), and biauricular breadth (AUB). Cranial size was calculated as the geometric mean of these variables, and shape dimensions were calculated as described by Darroch and Mosimann ( 1985 ). Cranial module and cranial capacity were also calculated. Samples consisted of 1,112 males and 668 females complete for those variables. Samples were organized into 10-year birth cohorts, with birth years ranging from 1820 to 1990. One-way ANOVA was used to test for variation among cohorts. The pattern of secular change was examined graphically and was compared with quality-of-life and environmental indicators, including stature, infant mortality, calories per person, and relative number of immigrants. All variables showed significant secular change, but BBH, XCB, and BNL responded most strongly. Over the past 170 years, crania became relatively higher, narrower, and larger with longer cranial bases. Both sexes changed, but female change was less pronounced than male change. The cranial variables tracked secular changes in stature, most prominently BNL. The highest correlation between a cranial variable and quality-of-life indicator was BBH and infant mortality. We are not able to identify specific causes of secular changes in cranial morphology. However, given that modern Americans have introduced themselves into a novel environment never before experienced by human populations, we consider it unlikely that it is pure plasticity. In addition to possible plastic responses, it is likely that selection, acting through the dramatic changes in infant mortality, is also involved.

  3. Propagation of Some Local Fig (Ficus carica L.) Cultivars by Hardwood Cuttings under the Field Conditions in Tunisia

    PubMed Central

    Aljane, Fateh; Nahdi, Sabrine

    2014-01-01

    This research was carried out in Southeast of Tunisia in 2009 and 2010, in order to study the propagation of six (Ficus carica L.) cultivars by using hardwood cuttings under the field conditions. The effect of the cultivars and the type of buds, shoots age, shoots length, and shoots diameter were recorded. Ten cuttings per cultivar and/or cutting types with three replications were planted in rooting unit. Percentage of root emergence and six morphological parameters of young fig plants were measured. Results showed that the responses of cuttings as fig nursery plants presented a high variability among the five cultivars. The most widely varied characters were % root emergence (RE) and cumulative growth of young plant (CG). The first one ranged from 10% to 90%, the second varied within 32 and 112 cm. Concerning the ‘‘BITHER” cultivar, 6 cutting types with different age, length, and diameter were evaluated. Results showed a great variation in % of root emergence (0–90%), length of nursery plant (3–77 cm), and number of roots/nursery plant (0–29 roots). The present research showed that the hardwood cutting of local fig cultivars can be propagated under field conditions in Southeast of Tunisia. PMID:27437458

  4. Neonatal outcomes following exposure in utero to fallout from Chernobyl.

    PubMed

    Hatch, Maureen; Little, Mark P; Brenner, Alina V; Cahoon, Elizabeth K; Tereshchenko, Valery; Chaikovska, Ludmyla; Pasteur, Igor; Likhtarov, Ilya; Bouville, Andre; Shpak, Victor; Bolshova, Olena; Zamotayeva, Galyna; Grantz, Katherine; Sun, Liping; Mabuchi, Kiyohiko; Albert, Paul; Tronko, Mykola

    2017-12-01

    Iodine 131 (I-131), the principal component of nuclear fallout from the Chernobyl accident, concentrates in the thyroid gland and may pose risks to fetal development. To evaluate this, neonatal outcomes following the accident in April of 1986 were investigated in a cohort of 2582 in utero-exposed individuals from northern Ukraine for whom estimates of fetal thyroid I-131 dose were available. We carried out a retrospective review of cohort members' prenatal, delivery and newborn records. The relationships of dose with neonatal anthropometrics and gestational length were modeled via linear regression with adjustment for potentially confounding variables. We found similar, statistically significant dose-dependent reductions in both head circumference (-1.0 cm/Gy, P = 0.005) and chest circumference (-0.9 cm/Gy, P = 0.023), as well as a similar but non-significant reduction in neonatal length (-0.6 cm/Gy, P = 0.169). Gestational length was significantly increased with increasing fetal dose (0.5 wks/Gy, P = 0.007). There was no significant (P > 0.1) effect of fetal dose on birth weight. The observed associations of radioiodine exposure with decreased head and chest circumference are consistent with those observed in the Japanese in utero-exposed atomic bomb survivors.

  5. Do climate variables and human density affect Achatina fulica (Bowditch) (Gastropoda: Pulmonata) shell length, total weight and condition factor?

    PubMed

    Albuquerque, F S; Peso-Aguiar, M C; Assunção-Albuquerque, M J T; Gálvez, L

    2009-08-01

    The length-weight relationship and condition factor have been broadly investigated in snails to obtain the index of physical condition of populations and evaluate habitat quality. Herein, our goal was to describe the best predictors that explain Achatina fulica biometrical parameters and well being in a recently introduced population. From November 2001 to November 2002, monthly snail samples were collected in Lauro de Freitas City, Bahia, Brazil. Shell length and total weight were measured in the laboratory and the potential curve and condition factor were calculated. Five environmental variables were considered: temperature range, mean temperature, humidity, precipitation and human density. Multiple regressions were used to generate models including multiple predictors, via model selection approach, and then ranked with AIC criteria. Partial regressions were used to obtain the separated coefficients of determination of climate and human density models. A total of 1.460 individuals were collected, presenting a shell length range between 4.8 to 102.5 mm (mean: 42.18 mm). The relationship between total length and total weight revealed that Achatina fulica presented a negative allometric growth. Simple regression indicated that humidity has a significant influence on A. fulica total length and weight. Temperature range was the main variable that influenced the condition factor. Multiple regressions showed that climatic and human variables explain a small proportion of the variance in shell length and total weight, but may explain up to 55.7% of the condition factor variance. Consequently, we believe that the well being and biometric parameters of A. fulica can be influenced by climatic and human density factors.

  6. Low-flow characteristics of streams in South Carolina

    USGS Publications Warehouse

    Feaster, Toby D.; Guimaraes, Wladmir B.

    2017-09-22

    An ongoing understanding of streamflow characteristics of the rivers and streams in South Carolina is important for the protection and preservation of the State’s water resources. Information concerning the low-flow characteristics of streams is especially important during critical flow periods, such as during the historic droughts that South Carolina has experienced in the past few decades.Between 2008 and 2016, the U.S. Geological Survey, in cooperation with the South Carolina Department of Health and Environmental Control, updated low-flow statistics at 106 continuous-record streamgages operated by the U.S. Geological Survey for the eight major river basins in South Carolina. The low-flow frequency statistics included the annual minimum 1-, 3-, 7-, 14-, 30-, 60-, and 90-day mean flows with recurrence intervals of 2, 5, 10, 20, 30, and 50 years, depending on the length of record available at the streamflow-gaging station. Computations of daily mean flow durations for the 5-, 10-, 25-, 50-, 75-, 90-, and 95-percent probability of exceedance also were included.This report summarizes the findings from publications generated during the 2008 to 2016 investigations. Trend analyses for the annual minimum 7-day average flows are provided as well as trend assessments of long-term annual precipitation data. Statewide variability in the annual minimum 7-day average flow is assessed at eight long-term (record lengths from 55 to 78 years) streamgages. If previous low-flow statistics were available, comparisons with the updated annual minimum 7-day average flow, having a 10-year recurrence interval, were made. In addition, methods for estimating low-flow statistics at ungaged locations near a gaged location are described.

  7. Record length requirement of long-range dependent teletraffic

    NASA Astrophysics Data System (ADS)

    Li, Ming

    2017-04-01

    This article contributes the highlights mainly in two folds. On the one hand, it presents a formula to compute the upper bound of the variance of the correlation periodogram measurement of teletraffic (traffic for short) with long-range dependence (LRD) for a given record length T and a given value of the Hurst parameter H (Theorems 1 and 2). On the other hand, it proposes two formulas for the computation of the variance upper bound of the correlation periodogram measurement of traffic of fractional Gaussian noise (fGn) type and the generalized Cauchy (GC) type, respectively (Corollaries 1 and 2). They may constitute a reference guideline of record length requirement of traffic with LRD. In addition, record length requirement for the correlation periodogram measurement of traffic with either the Schuster type or the Bartlett one is studied and the present results about it show that both types of periodograms may be used for the correlation measurement of traffic with a pre-desired variance bound of correlation estimation. Moreover, real traffic in the Internet Archive by the Special Interest Group on Data Communication under the Association for Computing Machinery of US (ACM SIGCOMM) is analyzed in the case study in this topic.

  8. An Assessment of the Length and Variability of Mercury's Magnetotail

    NASA Technical Reports Server (NTRS)

    Milan, S. E.; Slavin, J. A.

    2011-01-01

    We employ Mariner 10 measurements of the interplanetary magnetic field in the vicinity of Mercury to estimate the rate of magnetic reconnection between the interplanetary magnetic field and the Hermean magnetosphere. We derive a time-series of the open magnetic flux in Mercury's magnetosphere. from which we can deduce the length of the magnetotail The length of the magnetotail is shown to be highly variable. with open field lines stretching between 15R(sub H) and 8S0R(sub H) downstream of the planet (median 150R(sub H)). Scaling laws allow the tail length at perihelion to be deduced from the aphelion Mariner 10 observations.

  9. Outpatient Cocaine Abuse Treatment: Predictors of Success.

    ERIC Educational Resources Information Center

    Westhuis, David J.; Gwaltney, Lisa; Hayashi, Reiko

    2001-01-01

    Uses data from the U.S. Army's Alcohol and Drug Abuse Prevention and Control Program to analyze which treatment and demographic variables have an effect on cocaine treatment outcomes. Results suggest the following treatment variables had an effect on outcomes: type of treatment; length of time in treatment; and the length of time since the patient…

  10. Periodontal health and treatment needs among hospitalized chronic psychiatric patients in Istanbul, Turkey.

    PubMed

    Gurbuz, O; Alatas, G; Kurt, E; Dogan, F; Issever, H

    2011-03-01

    The aim of the study was to evaluate the periodontal health and treatment needs of chronically hospitalized psychiatric patients in Istanbul, Turkey. The subjects' periodontal health was recorded by the CPI (Community Periodontal Index) method. Of the 330 patients examined, 179 (52.5%) were males and 151 (47.5%) females. The mean age of the patients was 49.2 +/- 11.7 years. The majority (61.8%) was diagnosed with schizophrenia and 30.6% diagnosed with mental retardation. The mean length of hospitalization was 16.0 +/- 10.9 years. Healthy periodontal tissues (CPI 0) were found in 8.8% of the subjects. Bleeding on probing (CPI 1) was recorded in 6.3%, and dental calculus (CPI 2) in 51.8% of the subjects. These were determined as the worst findings. Altogether, 33% of the subjects had deep periodontal pockets, 14.2% with at least one 4- to 5-mm pocket (CPI 3), and 18.8% with at least one 6-mm pocket (CPI 4). The stepwise logistic regression analysis, between the final CPI score and seven variables including age, gender, psychiatric diagnosis, length of hospitalization, degree of helplessness, tooth brushing habits and smoking, showed that irregular tooth brushing habits and male gender were significant contributors to having a final CPI score of 2 or more. The regression analysis also showed that tooth brushing habits remained as an explanatory variable in CPI 0 coded subjects; helplessness and psychiatric diagnosis (mental retardation) in CPI 2; tooth brushing habits and psychiatric diagnosis (schizophrenia) in CPI 3; and only helplessness in CPI 4. The present study underlines a considerable need for prevention and treatment of periodontal disease among chronic psychiatric patients in Istanbul. Efforts need to be focused above all on raising this population's awareness of the importance of oral hygiene and on early diagnosis of periodontal problems.

  11. Variation of sperm head shape and tail length in a species of Australian hydromyine rodent: the spinifex hopping mouse, Notomys alexis.

    PubMed

    Bauer, M; Breed, W G

    2006-01-01

    In Australia, there are around 60 species of murid rodents that occur in the subfamily Hydromyinae, most of which produce highly complex, monomorphic, spermatozoa in which the head has an apical hook together with two ventral processes containing filamentous actin and a long tail of species-specific length. One of the few exceptions to this is the spinifex hopping mouse, Notomys alexis, whose spermatozoa have previously been shown to have pleiomorphic heads. In this study, the structural organisation of the sperm head has been investigated in more detail and the variability in length of the midpiece and total length of the sperm tail has been determined for this species. The findings confirm that pleiomorphic sperm heads are invariably present in these animals and that this variability is associated with that of the nucleus, although nuclear vacuoles were not evident. The total length of the sperm tail, as well as that of the midpiece, was also highly variable both within, as well as between, individual animals. The reason(s) for this high degree of variability in sperm morphology is not known but it may relate to a relaxation of the genetic control of sperm form owing to depressed levels of inter-male sperm competition.

  12. Single-shot optical recorder with sub-picosecond resolution and scalable record length on a semiconductor wafer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Muir, R.; Heebner, J.

    In this study, we demonstrate a novel, single-shot recording technology for transient optical signals. A resolution of 0.4 ps over a record length of 54 ps was demonstrated. Here, a pump pulse crossing through a signal samples a diagonal “slice” of space–time, enabling a camera to record spatially the time content of the signal. Unlike related X (2)-based cross-correlation techniques, here the signal is sampled through optically pumped carriers that modify the refractive index of a silicon wafer. Surrounding the wafer with birefringent retarders enables two time-staggered, orthogonally polarized signal copies to probe the wafer. Recombining the copies at amore » final crossed polarizer destructively interferes with them, except during the brief stagger window, where a differential phase shift is incurred. This enables the integrating response of the rapidly excited but persistent carriers to be optically differentiated. Lastly, this sampling mechanism has several advantages that enable scaling to long record lengths, including making use of large, inexpensive semiconductor wafers, eliminating the need for phase matching, broad insensitivity to the spectral and angular properties of the pump, and overall hardware simplicity.« less

  13. Single-shot optical recorder with sub-picosecond resolution and scalable record length on a semiconductor wafer

    DOE PAGES

    Muir, R.; Heebner, J.

    2017-10-24

    In this study, we demonstrate a novel, single-shot recording technology for transient optical signals. A resolution of 0.4 ps over a record length of 54 ps was demonstrated. Here, a pump pulse crossing through a signal samples a diagonal “slice” of space–time, enabling a camera to record spatially the time content of the signal. Unlike related X (2)-based cross-correlation techniques, here the signal is sampled through optically pumped carriers that modify the refractive index of a silicon wafer. Surrounding the wafer with birefringent retarders enables two time-staggered, orthogonally polarized signal copies to probe the wafer. Recombining the copies at amore » final crossed polarizer destructively interferes with them, except during the brief stagger window, where a differential phase shift is incurred. This enables the integrating response of the rapidly excited but persistent carriers to be optically differentiated. Lastly, this sampling mechanism has several advantages that enable scaling to long record lengths, including making use of large, inexpensive semiconductor wafers, eliminating the need for phase matching, broad insensitivity to the spectral and angular properties of the pump, and overall hardware simplicity.« less

  14. Factors Associated with Length of Hospital Stay among HIV Positive and HIV Negative Patients with Tuberculosis in Brazil

    PubMed Central

    Gonçalves, Maria Jacirema Ferreira; Ferreira, Alaidistania A.

    2013-01-01

    Objective Identify and analyze the factors associated to length of hospital stay among HIV positive and HIV negative patients with tuberculosis in Manaus city, state of Amazonas, Brazil, in 2010. Methods Epidemiological study with primary data obtained from monitoring of hospitalized patients with tuberculosis in Manaus. Data were collected by interviewing patients and analyzing medical records, according to the following study variables age, sex, co-morbidities, education, race, income, lifestyle, history of previous treatment or hospitalization due to tuberculosis, treatment regimen, adverse reactions, smear test, clinical form, type of discharge, and length of hospital stay. The associated factors were identified through chi-square or t-Student test at a 5% significance level. Results Income from 1 to 3 minimum wages (P = 0.028), pulmonary tuberculosis form (P = 0.011), negative smear test or no information in this regard (P = 0.014), initial 6-month treatment scheme (P = 0.029), and adverse drug reactions (P = 0.021) were associated to prolonged hospital stay in HIV positive patients. Conclusion We found out that although there were no significant differences in the length of hospital stay in HIV positive patients, all factors significantly associated to prolonged hospital stay occurred in this group of patients. This finding corroborates other studies indicating the severity of tuberculosis in HIV patients, which may also contribute to lengthen their hospital stay. PMID:23593227

  15. Spraguea lophii (Microsporidia) parasitizing blackbellied angler (Lophius budegassa) and angler (L. piscatorius) in European Atlantic waters

    NASA Astrophysics Data System (ADS)

    Landa, Jorge; Cañás, Lucía

    2017-12-01

    Blackbellied angler (Lophius budegassa) and angler (L. piscatorius) are two important commercial species in the Bay of Biscay and the European fisheries infected by the microsporidian parasite Spraguea lophii. Samplings of both anglerfish were performed from a nine year time-series (2006-2014) from commercial fleet and bottom research surveys operating in southern Bay of Biscay and Galician waters (ICES Div. VIIIc and IXa2), Celtic Sea (Div. VIIh), south-western Ireland (Div. VIIj and VIIk), western Ireland and Porcupine Bank (Div. VIIb and VIIc). Length and sex of fish and presence or absence of the parasite were recorded. The prevalence by Spraguea was used to analyse the infection level. The role of each variable (fish length, fish sex, geographical area and year) and the interactions among them on the Spraguea prevalence were analyzed by using a binomial GLM. Area and fish length had a more relevant effect on the infestation of both anglerfish, while the impact of the year and fish sex was less evident. The Spraguea prevalence by area ranged between 11% and 52% in L. budegassa and between 39% and 66% in L. piscatorius. This is the first study in which the prevalence of this parasite in L. budegassa is analyzed in several areas and inter-annually compared. A non-linear relationship with a sharp increment of the prevalence with fish length was obtained in both anglerfish. The results were compared with those from the scarce previous studies and discussed.

  16. Are gestational age, birth weight, and birth length indicators of favorable fetal growth conditions? A structural equation analysis of Filipino infants.

    PubMed

    Bollen, Kenneth A; Noble, Mark D; Adair, Linda S

    2013-07-30

    The fetal origins hypothesis emphasizes the life-long health impacts of prenatal conditions. Birth weight, birth length, and gestational age are indicators of the fetal environment. However, these variables often have missing data and are subject to random and systematic errors caused by delays in measurement, differences in measurement instruments, and human error. With data from the Cebu (Philippines) Longitudinal Health and Nutrition Survey, we use structural equation models, to explore random and systematic errors in these birth outcome measures, to analyze how maternal characteristics relate to birth outcomes, and to take account of missing data. We assess whether birth weight, birth length, and gestational age are influenced by a single latent variable that we call favorable fetal growth conditions (FFGC) and if so, which variable is most closely related to FFGC. We find that a model with FFGC as a latent variable fits as well as a less parsimonious model that has birth weight, birth length, and gestational age as distinct individual variables. We also demonstrate that birth weight is more reliably measured than is gestational age. FFGCs were significantly influenced by taller maternal stature, better nutritional stores indexed by maternal arm fat and muscle area during pregnancy, higher birth order, avoidance of smoking, and maternal age 20-35 years. Effects of maternal characteristics on newborn weight, length, and gestational age were largely indirect, operating through FFGC. Copyright © 2013 John Wiley & Sons, Ltd.

  17. Mechanical behaviour of condenser microphone in mechanomyography.

    PubMed

    Watakabe, M; Mita, K; Akataki, K; Itoh, Y

    2001-03-01

    Condenser microphones (MIC) have been widely used in mechanomyography, together with accelerometers and piezoelectric contact sensors. The aim of the present investigation was to clarify the mechanical variable (acceleration, velocity or displacement) indicated by the signal from a MIC transducer using a mechanical sinusoidal vibration system. In addition, the mechanomyogram (MMG) was recorded simultaneously with a MIC transducer and accelerometer (ACC) during voluntary contractions to confirm the mechanical variable reflected by the actual MMG and to examine the influence of motion artifact on the MMG. To measure the displacement-frequency response, mechanical sinusoidal vibrations of 3 to 300 Hz were applied to the MIC transducer with different sizes of air chambers (5, 10, 15 and 20 mm in diameter and 15, 20 or 25 mm long). The MIC transducer showed a linear relationship between the output amplitude and the vibration displacement, however, its frequency response declined with decreasing diameter and decreasing length of the air chamber. In fact, the cut-off frequency (-3dB) of the MIC transducer with the 5-mm-diameter chamber was 10, 8 and 4 Hz for the length 15, 20 and 25 mm, respectively. The air chamber with at least a diameter of 10 mm and a length of 15 mm is recommended for the MIC transducer. The sensitivity of this MIC transducer arrangement was 92 mV microm(-1) when excited at 100 Hz. During voluntary contraction, the amplitude spectral density function of the MMG from the MIC transducer resembled that of the double integral of the ACC transducer signal. The angle of the MIC transducer was delayed by 180 degrees in relation to the ACC transducer signal. The sensitivity of the MIC transducer was reduced to one-third because of the peculiar volume change of air chamber when the MMG was detected on the surface of the skin. In addition, the MIC transducer was contaminated by a smaller motion artifact than that from the ACC transducer. The maximal peak amplitude of the MIC and ACC transducer signal with the motion artifact was 7.7 and 12.3 times as much as the RMS amplitude of each signal without the motion artifact, respectively. These findings suggest that the MIC transducer acts as a displacement meter in the MMG. The MIC transducer seems to be a possible candidate for recording the MMG during dynamic muscle contractions as well as during sustained contractions.

  18. Importance of Viral Sequence Length and Number of Variable and Informative Sites in Analysis of HIV Clustering.

    PubMed

    Novitsky, Vlad; Moyo, Sikhulile; Lei, Quanhong; DeGruttola, Victor; Essex, M

    2015-05-01

    To improve the methodology of HIV cluster analysis, we addressed how analysis of HIV clustering is associated with parameters that can affect the outcome of viral clustering. The extent of HIV clustering and tree certainty was compared between 401 HIV-1C near full-length genome sequences and subgenomic regions retrieved from the LANL HIV Database. Sliding window analysis was based on 99 windows of 1,000 bp and 45 windows of 2,000 bp. Potential associations between the extent of HIV clustering and sequence length and the number of variable and informative sites were evaluated. The near full-length genome HIV sequences showed the highest extent of HIV clustering and the highest tree certainty. At the bootstrap threshold of 0.80 in maximum likelihood (ML) analysis, 58.9% of near full-length HIV-1C sequences but only 15.5% of partial pol sequences (ViroSeq) were found in clusters. Among HIV-1 structural genes, pol showed the highest extent of clustering (38.9% at a bootstrap threshold of 0.80), although it was significantly lower than in the near full-length genome sequences. The extent of HIV clustering was significantly higher for sliding windows of 2,000 bp than 1,000 bp. We found a strong association between the sequence length and proportion of HIV sequences in clusters, and a moderate association between the number of variable and informative sites and the proportion of HIV sequences in clusters. In HIV cluster analysis, the extent of detectable HIV clustering is directly associated with the length of viral sequences used, as well as the number of variable and informative sites. Near full-length genome sequences could provide the most informative HIV cluster analysis. Selected subgenomic regions with a high extent of HIV clustering and high tree certainty could also be considered as a second choice.

  19. Importance of Viral Sequence Length and Number of Variable and Informative Sites in Analysis of HIV Clustering

    PubMed Central

    Novitsky, Vlad; Moyo, Sikhulile; Lei, Quanhong; DeGruttola, Victor

    2015-01-01

    Abstract To improve the methodology of HIV cluster analysis, we addressed how analysis of HIV clustering is associated with parameters that can affect the outcome of viral clustering. The extent of HIV clustering and tree certainty was compared between 401 HIV-1C near full-length genome sequences and subgenomic regions retrieved from the LANL HIV Database. Sliding window analysis was based on 99 windows of 1,000 bp and 45 windows of 2,000 bp. Potential associations between the extent of HIV clustering and sequence length and the number of variable and informative sites were evaluated. The near full-length genome HIV sequences showed the highest extent of HIV clustering and the highest tree certainty. At the bootstrap threshold of 0.80 in maximum likelihood (ML) analysis, 58.9% of near full-length HIV-1C sequences but only 15.5% of partial pol sequences (ViroSeq) were found in clusters. Among HIV-1 structural genes, pol showed the highest extent of clustering (38.9% at a bootstrap threshold of 0.80), although it was significantly lower than in the near full-length genome sequences. The extent of HIV clustering was significantly higher for sliding windows of 2,000 bp than 1,000 bp. We found a strong association between the sequence length and proportion of HIV sequences in clusters, and a moderate association between the number of variable and informative sites and the proportion of HIV sequences in clusters. In HIV cluster analysis, the extent of detectable HIV clustering is directly associated with the length of viral sequences used, as well as the number of variable and informative sites. Near full-length genome sequences could provide the most informative HIV cluster analysis. Selected subgenomic regions with a high extent of HIV clustering and high tree certainty could also be considered as a second choice. PMID:25560745

  20. Data Processing Aspects of MEDLARS

    PubMed Central

    Austin, Charles J.

    1964-01-01

    The speed and volume requirements of MEDLARS necessitate the use of high-speed data processing equipment, including paper-tape typewriters, a digital computer, and a special device for producing photo-composed output. Input to the system is of three types: variable source data, including citations from the literature and search requests; changes to such master files as the medical subject headings list and the journal record file; and operating instructions such as computer programs and procedures for machine operators. MEDLARS builds two major stores of data on magnetic tape. The Processed Citation File includes bibliographic citations in expanded form for high-quality printing at periodic intervals. The Compressed Citation File is a coded, time-sequential citation store which is used for high-speed searching against demand request input. Major design considerations include converting variable-length, alphanumeric data to mechanical form quickly and accurately; serial searching by the computer within a reasonable period of time; high-speed printing that must be of graphic quality; and efficient maintenance of various complex computer files. PMID:14119287

  1. DATA PROCESSING ASPECTS OF MEDLARS.

    PubMed

    AUSTIN, C J

    1964-01-01

    The speed and volume requirements of MEDLARS necessitate the use of high-speed data processing equipment, including paper-tape typewriters, a digital computer, and a special device for producing photo-composed output. Input to the system is of three types: variable source data, including citations from the literature and search requests; changes to such master files as the medical subject headings list and the journal record file; and operating instructions such as computer programs and procedures for machine operators. MEDLARS builds two major stores of data on magnetic tape. The Processed Citation File includes bibliographic citations in expanded form for high-quality printing at periodic intervals. The Compressed Citation File is a coded, time-sequential citation store which is used for high-speed searching against demand request input. Major design considerations include converting variable-length, alphanumeric data to mechanical form quickly and accurately; serial searching by the computer within a reasonable period of time; high-speed printing that must be of graphic quality; and efficient maintenance of various complex computer files.

  2. Alternating absorption features during attosecond-pulse propagation in a laser-controlled gaseous medium

    NASA Astrophysics Data System (ADS)

    Pfeiffer, Adrian N.; Bell, M. Justine; Beck, Annelise R.; Mashiko, Hiroki; Neumark, Daniel M.; Leone, Stephen R.

    2013-11-01

    Recording the transmitted spectrum of a weak attosecond pulse through a medium, while a strong femtosecond pulse copropagates at variable delay, probes the strong-field dynamics of atoms, molecules, and solids. Usually, the interpretation of these measurements is based on the assumption of a thin medium. Here, the propagation through a macroscopic medium of helium atoms in the region of fully allowed resonances is investigated both theoretically and experimentally. The propagation has dramatic effects on the transient spectrum even at relatively low pressures (50 mbar) and short propagation lengths (1 mm). The absorption does not evolve monotonically with the product of propagation distance and pressure, but regions with characteristics of Lorentz line shapes and characteristics of Fano line shapes alternate. Criteria are deduced to estimate whether macroscopic effects can be neglected or not in a transient absorption experiment. Furthermore, the theory in the limit of single-atom response yields a general equation for Lorentz- and Fano-type line shapes at variable pulse delay.

  3. First report of genotype #65 of Toxoplasma gondii in pigs.

    PubMed

    Samico-Fernandes, Erika Fernanda Torres; de Melo, Renata Pimentel Bandeira; de Cássia Peixoto Kim, Pomy; de Almeida, Jonatas Campos; de Barros, Luiz Daniel; Garcia, João Luis; da Silva, Jean Carlos Ramos; Mota, Rinaldo Aparecido

    2015-10-01

    The aim of the present study was to isolate and genotype Toxoplasma gondii from pigs slaughtered for human consumption in northeastern Brazil. Indirect immunofluorescence antibody test (IFAT) was used to screen positive pigs. Tissues samples of animals with antibody titers ≥64 were submitted to bioassay in mice. One isolate of T. gondii was obtained, and the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique, using 11 markers (SAG1, SAG2, altSAG2, SAG3, BTUB, GRA6, c228, c292, L358, PK1, and APICO), was applied to evaluate the genetic variability. DNA from reference strains was used as a positive control. By means of genetic analysis, genotype ToxoDB #65 was identified, which is considered an atypical strain. This is the first record of genotype #65 in pigs. Thus, further studies in this region are necessary to determine the genetic variability of T. gondii in pigs and possible impact on public health.

  4. Athletic Training Student Core Competency Implementation During Patient Encounters.

    PubMed

    Cavallario, Julie M; Van Lunen, Bonnie L; Hoch, Johanna M; Hoch, Matthew; Manspeaker, Sarah A; Pribesh, Shana L

    2018-03-01

      Health care research evidence suggests that early patient encounters (PEs), as well as the purposeful implementation of professional core competencies (CCs), for athletic training students (ATSs) may be beneficial to their ability to provide care. However, no investigators have related facets of the clinical education experience with CC implementation as a form of summative assessment of the clinical experience.   To determine the relationship between the frequency and length of PEs, as well as the student's role and clinical site during PEs, and the students' perceived CC implementation during these encounters.   Cross-sectional study.   Professional athletic training program, National Collegiate Athletic Association Division I institution.   We purposefully recruited 1 athletic training program that used E*Value software; 40 participants (31 females, 9 males) enrolled in the professional phase (12 first year, 14 second year, 14 third year) participated.   Participants viewed a 20-minute recorded CC educational module followed by educational handouts, which were also posted online for reference throughout the semester. The E*Value software was used to track PEs, including the type of encounter (ie, actual patient, practice encounter, didactic practice scenario), the type of site where the encounter occurred (university, high school), and the participant's role (observed, assisted, performed), as well as responses to an added block of questions indicating which, if any, of the CCs were implemented during the PE.   Variables per patient were PE length (minutes), participant role, site at which the encounter occurred, and whether any of the 6 CCs were implemented ( yes/ no). Variables per participant were average encounter length (minutes), encounter frequency, modal role, clinical site assignment, and the number of times each CC was implemented. Separate 1-way analyses of variance were used to examine the relationships between role or clinical site and implementation of total number of CCs. Multiple linear regressions were used to determine how the average length and frequency of PEs were related to the average and total number of implemented CCs. Binary logistic regression models indicated how the length of each encounter, role of the participant, and type of clinical site related to the implementation of each CC.   The roles of participants during PEs were related to their ability to implement the total number of CCs ( F = 103.48, P < .001). Those who observed were likely to implement fewer total CCs than those who assisted (M diff = -0.29, P < .001); those who assisted were likely to implement more total CCs than those who performed (M diff = 0.32, P < .001). Frequency of encounters was the only significant variable in the model examining all independent variables with CC implementation ( b 4,32 = 3.34, t = 9.46, P < .001).   The role of the student, namely assisting during PEs, and the volume of PEs should be considered priorities for students to promote greater CC implementation.

  5. Gender differences in foot shape: a study of Chinese young adults.

    PubMed

    Hong, Youlian; Wang, Lin; Xu, Dong Qing; Li, Jing Xian

    2011-06-01

    One important extrinsic factor that causes foot deformity and pain in women is footwear. Women's sports shoes are designed as smaller versions of men's shoes. Based on this, the current study aims to identify foot shape in 1,236 Chinese young adult men and 1,085 Chinese young adult women. Three-dimensional foot shape data were collected through video filming. Nineteen foot shape variables were measured, including girth (4 variables), length (4 variables), width (3 variables), height (7 variables), and angle (1 variable). A comparison of foot measures within the range of the common foot length (FL) categories indicates that women showed significantly smaller values of foot measures in width, height, and girth than men. Three foot types were classified, and distributions of different foot shapes within the same FL were found between women and men. Foot width, medial ball length, ball angle, and instep height showed significant differences among foot types in the same FL for both genders. There were differences in the foot shape between Chinese young women and men, which should be considered in the design of Chinese young adults' sports shoes.

  6. A Two-length Scale Turbulence Model for Single-phase Multi-fluid Mixing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schwarzkopf, J. D.; Livescu, D.; Baltzer, J. R.

    2015-09-08

    A two-length scale, second moment turbulence model (Reynolds averaged Navier-Stokes, RANS) is proposed to capture a wide variety of single-phase flows, spanning from incompressible flows with single fluids and mixtures of different density fluids (variable density flows) to flows over shock waves. The two-length scale model was developed to address an inconsistency present in the single-length scale models, e.g. the inability to match both variable density homogeneous Rayleigh-Taylor turbulence and Rayleigh-Taylor induced turbulence, as well as the inability to match both homogeneous shear and free shear flows. The two-length scale model focuses on separating the decay and transport length scales,more » as the two physical processes are generally different in inhomogeneous turbulence. This allows reasonable comparisons with statistics and spreading rates over such a wide range of turbulent flows using a common set of model coefficients. The specific canonical flows considered for calibrating the model include homogeneous shear, single-phase incompressible shear driven turbulence, variable density homogeneous Rayleigh-Taylor turbulence, Rayleigh-Taylor induced turbulence, and shocked isotropic turbulence. The second moment model shows to compare reasonably well with direct numerical simulations (DNS), experiments, and theory in most cases. The model was then applied to variable density shear layer and shock tube data and shows to be in reasonable agreement with DNS and experiments. Additionally, the importance of using DNS to calibrate and assess RANS type turbulence models is highlighted.« less

  7. Job stress, unwinding and drinking in transit operators.

    PubMed

    Delaney, William P; Grube, Joel W; Greiner, Birgit; Fisher, June M; Ragland, David R

    2002-07-01

    This study tests the spillover model of the effects of work stress on after-work drinking, using the variable "length of time to unwind" as a mediator. A total of 1,974 transit operators were contacted and 1,553 (79%) of them participated in a personal interview. Complete data on the variables in this analysis were available for 1,208 respondents (84% men). Using latent variable structural equation modeling, a model was tested that predicted that daily job problems, skipped meals and less social support from supervisor would increase alcohol consumption through the mediator, length of time to unwind and relax after work. Increased alcohol consumption was, in turn, hypothesized to increase drinking problems. As predicted, skipped meals and daily job problems increased length of time to unwind and had an indirect positive relationship with overall drinking, even when controlling for drinking norms and demographic variables. Overall drinking was positively associated with drinking problems. Supervisor support at work, however, did not significantly influence length of time to unwind. Difficulty unwinding (longer time to unwind) did not have direct effects on drinking problems; however, indirect effects through overall drinking were observed. These results provide preliminary support for the mediating role of length of time to unwind and relax after work in a spillover model of the stress-drinking relationship. This research introduces a new mediator and empirical links between job problems, length of time to unwind, drinking and drinking problems, which ground more substantively the domains of work stress and alcohol consumption.

  8. Effect of different dry period lengths on milk production and somatic cell count in subsequent lactations in commercial Dutch dairy herds.

    PubMed

    Steeneveld, W; Schukken, Y H; van Knegsel, A T M; Hogeveen, H

    2013-05-01

    Shortening the dry period (DP) has been proposed as a management strategy to improve energy balance in early lactation. It is well known that both shortening and complete omission of the DP reduces milk production in the subsequent lactations. In most of these studies milk production data were obtained from planned animal experiments where cows were randomly assigned to DP length treatments, and cow management and diet composition did not differ among treatments. It may therefore be hypothesized that cows on commercial herds which apply a no-DP or short-DP-strategy, and support this by management adjustments, will have a less dramatic reduction in milk production. In this study, milk production and somatic cell count (SCC) following different DP lengths was investigated under commercial circumstances. Milk production of 342 cows (2,077 test-day records) was available from 5 Dutch commercial dairy herds which started a no DP-strategy for all cows. Test days of the year before applying the no-DP strategy are used as control (323 cows, 1,717 test-day records). Six other herds applied an individual cow approach and have different preplanned DP lengths within one herd. From these herds, information on 81 cows (482 test-day records) with a DP length between 0 and 20 d, 127 cows (925 test-day records) with a DP length between 21 and 35 d, and 143 cows (1,075 test-day records) with a DP length of more than 35 d was available. A generalized linear model incorporating an autoregressive covariance structure accounting for repeated test-day yields within cow was developed to estimate the daily yield (milk, fat and protein) and SCC of all cows. Applying no DP for all cows in the herd resulted in a reduction in postpartum milk production compared with within-herd control lactations (until 305 DIM) between 3.2 and 9.1 kg/d, which was a reduction of 12 and 32%, respectively. For the 6 herds that applied an individual cow approach with different preplanned DP lengths, the cow-specific DP strategy was based on milk production and SCC approximately 2 mo before calving. Cows with a preplanned DP length ranging between 0 and 20 d had a reduction in postpartum milk production between 5.7 and 13 kg/d compared with cows with a DP length of >35 d. Cows with a preplanned DP length ranging from 21 to 35 d had a numerically lower milk production (between 0.6 and 5.3 kg/d) than cows with a preplanned DP length of >35 d, but this difference was significant in only one herd. When corrected for milk yield, no difference in postpartum SCC for cows with different DP lengths was found. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  9. A model of acoustic interspeaker variability based on the concept of formant-cavity affiliation

    NASA Astrophysics Data System (ADS)

    Apostol, Lian; Perrier, Pascal; Bailly, Gérard

    2004-01-01

    A method is proposed to model the interspeaker variability of formant patterns for oral vowels. It is assumed that this variability originates in the differences existing among speakers in the respective lengths of their front and back vocal-tract cavities. In order to characterize, from the spectral description of the acoustic speech signal, these vocal-tract differences between speakers, each formant is interpreted, according to the concept of formant-cavity affiliation, as a resonance of a specific vocal-tract cavity. Its frequency can thus be directly related to the corresponding cavity length, and a transformation model can be proposed from a speaker A to a speaker B on the basis of the frequency ratios of the formants corresponding to the same resonances. In order to minimize the number of sounds to be recorded for each speaker in order to carry out this speaker transformation, the frequency ratios are exactly computed only for the three extreme cardinal vowels [eye, aye, you] and they are approximated for the remaining vowels through an interpolation function. The method is evaluated through its capacity to transform the (F1,F2) formant patterns of eight oral vowels pronounced by five male speakers into the (F1,F2) patterns of the corresponding vowels generated by an articulatory model of the vocal tract. The resulting formant patterns are compared to those provided by normalization techniques published in the literature. The proposed method is found to be efficient, but a number of limitations are also observed and discussed. These limitations can be associated with the formant-cavity affiliation model itself or with a possible influence of speaker-specific vocal-tract geometry in the cross-sectional direction, which the model might not have taken into account.

  10. Mitral valve morphology assessed by three-dimensional transthoracic echocardiography in healthy dogs and dogs with myxomatous mitral valve disease.

    PubMed

    Menciotti, G; Borgarelli, M; Aherne, M; Wesselowski, S; Häggström, J; Ljungvall, I; Lahmers, S M; Abbott, J A

    2017-04-01

    To assess differences in morphology of the mitral valve (MV) between healthy dogs and dogs affected by myxomatous mitral valve disease (MMVD) using real-time transthoracic three-dimensional echocardiography (RT3DE). Thirty-four were normal dogs and 79 dogs were affected by MMVD. Real-time transthoracic three-dimensional echocardiography mitral datasets were digitally recorded and analyzed using dedicated software. The following variables were obtained and compared between healthy dogs and dogs with MMVD at different stages: antero-posterior annulus diameter, anterolateral-posteromedial annulus diameter, commissural diameter, annulus height, annulus circumference, annulus area, anterior leaflet length, anterior leaflet area, posterior leaflet length, posterior leaflet area, non-planar angle, annulus sphericity index, tenting height, tenting area, tenting volume, the ratio of annulus height and commissural diameter. Dogs with MMVD had a more circular MV annulus compared to healthy dogs as demonstrated by an increased annulus sphericity index (p=0.0179). Affected dogs had a less saddle-shaped MV manifest as a decreased annulus height to commissural width ratio (p=0.0004). Tenting height (p<0.0001), area (p<0.0001), and volume (p<0.0001) were less in affected dogs. Real-time transthoracic three-dimensional echocardiography analysis demonstrated that dogs affected by MMVD had a more circular and less saddle-shaped MV annulus, as well as reduced tenting height area and volume, compared to healthy dogs. Multiple variables differed between dogs at different stages of MMVD. Diagnostic and prognostic utility of these variables, and the significance of these changes in the pathogenesis and natural history of MMVD, require further attention. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Regionalization of precipitation characteristics in Iran's Lake Urmia basin

    NASA Astrophysics Data System (ADS)

    Fazel, Nasim; Berndtsson, Ronny; Uvo, Cintia Bertacchi; Madani, Kaveh; Kløve, Bjørn

    2018-04-01

    Lake Urmia in northwest Iran, once one of the largest hypersaline lakes in the world, has shrunk by almost 90% in area and 80% in volume during the last four decades. To improve the understanding of regional differences in water availability throughout the region and to refine the existing information on precipitation variability, this study investigated the spatial pattern of precipitation for the Lake Urmia basin. Daily rainfall time series from 122 precipitation stations with different record lengths were used to extract 15 statistical descriptors comprising 25th percentile, 75th percentile, and coefficient of variation for annual and seasonal total precipitation. Principal component analysis in association with cluster analysis identified three main homogeneous precipitation groups in the lake basin. The first sub-region (group 1) includes stations located in the center and southeast; the second sub-region (group 2) covers mostly northern and northeastern part of the basin, and the third sub-region (group 3) covers the western and southern edges of the basin. Results of principal component (PC) and clustering analyses showed that seasonal precipitation variation is the most important feature controlling the spatial pattern of precipitation in the lake basin. The 25th and 75th percentiles of winter and autumn are the most important variables controlling the spatial pattern of the first rotated principal component explaining about 32% of the total variance. Summer and spring precipitation variations are the most important variables in the second and third rotated principal components, respectively. Seasonal variation in precipitation amount and seasonality are explained by topography and influenced by the lake and westerly winds that are related to the strength of the North Atlantic Oscillation. Despite using incomplete time series with different lengths, the identified sub-regions are physically meaningful.

  12. Estimating peak discharges, flood volumes, and hydrograph shapes of small ungaged urban streams in Ohio

    USGS Publications Warehouse

    Sherwood, J.M.

    1986-01-01

    Methods are presented for estimating peak discharges, flood volumes and hydrograph shapes of small (less than 5 sq mi) urban streams in Ohio. Examples of how to use the various regression equations and estimating techniques also are presented. Multiple-regression equations were developed for estimating peak discharges having recurrence intervals of 2, 5, 10, 25, 50, and 100 years. The significant independent variables affecting peak discharge are drainage area, main-channel slope, average basin-elevation index, and basin-development factor. Standard errors of regression and prediction for the peak discharge equations range from +/-37% to +/-41%. An equation also was developed to estimate the flood volume of a given peak discharge. Peak discharge, drainage area, main-channel slope, and basin-development factor were found to be the significant independent variables affecting flood volumes for given peak discharges. The standard error of regression for the volume equation is +/-52%. A technique is described for estimating the shape of a runoff hydrograph by applying a specific peak discharge and the estimated lagtime to a dimensionless hydrograph. An equation for estimating the lagtime of a basin was developed. Two variables--main-channel length divided by the square root of the main-channel slope and basin-development factor--have a significant effect on basin lagtime. The standard error of regression for the lagtime equation is +/-48%. The data base for the study was established by collecting rainfall-runoff data at 30 basins distributed throughout several metropolitan areas of Ohio. Five to eight years of data were collected at a 5-min record interval. The USGS rainfall-runoff model A634 was calibrated for each site. The calibrated models were used in conjunction with long-term rainfall records to generate a long-term streamflow record for each site. Each annual peak-discharge record was fitted to a Log-Pearson Type III frequency curve. Multiple-regression techniques were then used to analyze the peak discharge data as a function of the basin characteristics of the 30 sites. (Author 's abstract)

  13. Explaining direct care resource use of nursing home residents: findings from time studies in four states.

    PubMed

    Arling, Greg; Kane, Robert L; Mueller, Christine; Lewis, Teresa

    2007-04-01

    To explain variation in direct care resource use (RU) of nursing home residents based on the Resource Utilization Groups III (RUG-III) classification system and other resident- and unit-level explanatory variables. Primary data were collected on 5,314 nursing home residents in 156 nursing units in 105 facilities from four states (CO, IN, MN, MS) from 1998 to 2004. Study Design. Nurses and other direct care staff recorded resident-specific and other time caring for all residents on sampled nursing units. Care time was linked to resident data from the Minimum Data Set assessment instrument. Major variables were: RUG-III group (34-group), other health and functional conditions, licensed and other professional minutes per day, unlicensed minutes per day, and direct care RU (wage-weighted minutes). Resident- and unit-level relationships were examined through hierarchical linear modeling. Time study data were recorded with hand-held computers, verified for accuracy by project staff at the data collection sites and then merged into resident and unit-level data sets. Resident care time and RU varied between and within nursing units. RUG-III group was related to RU; variables such as length of stay and unit percentage of high acuity residents also were significantly related. Case-mix indices (CMIs) constructed from study data displayed much less variation across RUG-III groups than CMIs from earlier time studies. Results from earlier time studies may not be representative of care patterns of Medicaid and private pay residents. New RUG-III CMIs should be developed to better reflect the relative costs of caring for these residents.

  14. Estimating length of avian incubation and nestling stages in afrotropical forest birds from interval-censored nest records

    USGS Publications Warehouse

    Stanley, T.R.; Newmark, W.D.

    2010-01-01

    In the East Usambara Mountains in northeast Tanzania, research on the effects of forest fragmentation and disturbance on nest survival in understory birds resulted in the accumulation of 1,002 nest records between 2003 and 2008 for 8 poorly studied species. Because information on the length of the incubation and nestling stages in these species is nonexistent or sparse, our objectives in this study were (1) to estimate the length of the incubation and nestling stage and (2) to compute nest survival using these estimates in combination with calculated daily survival probability. Because our data were interval censored, we developed and applied two new statistical methods to estimate stage length. In the 8 species studied, the incubation stage lasted 9.6-21.8 days and the nestling stage 13.9-21.2 days. Combining these results with estimates of daily survival probability, we found that nest survival ranged from 6.0% to 12.5%. We conclude that our methodology for estimating stage lengths from interval-censored nest records is a reasonable and practical approach in the presence of interval-censored data. ?? 2010 The American Ornithologists' Union.

  15. Focal length hysteresis of a double-liquid lens based on electrowetting

    NASA Astrophysics Data System (ADS)

    Peng, Runling; Wang, Dazhen; Hu, Zhiwei; Chen, Jiabi; Zhuang, Songlin

    2013-02-01

    In this paper, an extended Young equation especially suited for an ideal cylindrical double-liquid variable-focus lens is derived by means of an energy minimization method. Based on the extended Young equation, a kind of focal length hysteresis effect is introduced into the double-liquid variable-focus lens. Such an effect can be explained theoretically by adding a force of friction to the tri-phase contact line. Theoretical analysis shows that the focal length at a particular voltage can be different depending on whether the applied voltage is increasing or decreasing, that is, there is a focal length hysteresis effect. Moreover, the focal length at a particular voltage must be larger when the voltage is rising than when it is dropping. These conclusions are also verified by experiments.

  16. Relationship between balance performance in the elderly and some anthropometric variables.

    PubMed

    Fabunmi, A A; Gbiri, C A

    2008-12-01

    Ability to maintain either static or dynamic balance has been found to be influenced by many factors such as height and weight in the elderly. The relationship between other anthropometric variables and balance performance among elderly Nigerians has not been widely studied. The aim of this study was to investigate the relationship between these other anthropometric variables and balance performance among old individuals aged >60 years in Ibadan, Nigeria. The study used the ex-post facto design and involved two hundred and three apparently healthy (103 males and 100 females) elderly participants with ages between 60 years and 74 years, selected using multiple step-wise sampling techniques from churches, mosques and market place within Ibadan. They were without history of neurological problem, postural hypotension, orthopeadic conditions or injury to the back and/or upper and lower extremities within the past one year. Selected anthropometric variables were measured, Sharpened Romberg Test (SRT) and Functional Reach Test (FRT) was used to assess static balance and dynamic balance respectively. All data were summarized using range, mean and standard deviation. Pearson's product moment correlation coefficient was used to determine the relationship between the physical characteristics, anthropometric variables and performance on each of the two balance tests. The results showed that there were low but significant positive correlations between performance on FRT and each of height, weight, trunk length, foot length, shoulder girth and hip girth. (p<0.05). There was low significant and positive correlation between SRT with eyes closed and arm length, foot length and shoulder girth. (p<0.05) and there was low but significant positive correlation between SRT with eyes opened and shoulder girth and foot length (P<0.05). Anthropometric variables affect balance performances in apparently healthy elderly.

  17. Liquid Lens module with wide field-of-view and variable focal length

    NASA Astrophysics Data System (ADS)

    Seo, Sang Won; Han, Seungoh; Seo, Jun Ho; Choi, Woo Bum; Sung, Man Young

    2010-12-01

    A novel wide angle and variable-focus imaging module based on a miniaturized liquid lens is presented for capsule endoscopy applications. For these applications, it is desirable to have features such as a wide field of view (FOV), variable focus, small size, and low power consumption, thereby taking full advantage of the miniaturized liquid lens. The proposed imaging module has three aspheric plastic lenses for a wide FOV, and one liquid lens that can change the focal length by as much as 24.5 cm with a bias voltage difference of 23 Vrms for variable focusing. The assembled lens module has an overall length of 8.4 mm and a FOV of 120.5°. The realized imaging module including the proposed lenses is small enough to be inserted into a capsule endoscope, and it is expected to improve the diagnostic capability of capsule endoscopes.

  18. Paraxial ray solution for liquid-filled variable focus lenses

    NASA Astrophysics Data System (ADS)

    Wang, Lihui; Oku, Hiromasa; Ishikawa, Masatoshi

    2017-12-01

    We propose a general solution for determining the cardinal points and effective focal length of a liquid-filled variable focus lens to aid in understanding the dynamic behavior of the lens when the focal length is changed. A prototype of a variable focus lens was fabricated and used to validate the solution. A simplified solution was also presented that can be used to quickly and conveniently calculate the performance of the lens. We expect that the proposed solutions will improve the design of optical systems that contain variable focus lenses, such as machine vision systems with zoom and focus functions.

  19. Extracting the respiration cycle lengths from ECG signal recorded with bed sheet electrodes

    NASA Astrophysics Data System (ADS)

    Vehkaoja, A.; Peltokangas, M.; Lekkala, J.

    2013-09-01

    A method for recognizing the respiration cycle lengths from the electrocardiographic (ECG) signal recorded with textile electrodes that are attached to a bed sheet is proposed. The method uses two features extracted from the ECG that are affected by the respiration: respiratory sinus arrhythmia and the amplitude of the R-peaks. The proposed method was tested in one hour long recordings with ten healthy young adults. A relative mean absolute error of 5.6 % was achieved when the algorithm was able to provide a result for approximately 40 % of the time. 90 % of the values were within 0.5 s and 97 % within 1 s from the reference respiration value. In addition to the instantaneous respiration cycle lengths, also the mean values during 1 and 5 minutes epochs are calculated. The effect of the ECG signal source is evaluated by calculating the result also from the simultaneously recorded reference ECG signal. The acquired respiration information can be used in the estimation of sleep quality and the detection of sleep disorders.

  20. Generation of Shear Motion from an Isotropic Explosion Source by Scattering in Heterogeneous Media

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hirakawa, Evan; Pitarka, Arben; Mellors, Robert

    One challenging task in explosion seismology is the development of physical models for explaining the generation of S waves during underground explosions. Recent analysis of ground motion from chemical explosions during the Source Physics Experiment (Pitarka et al., 2015) suggests that, although a large component of shear motion was generated directly at the source, additional scattering from heterogeneous velocity structure and topography is necessary to better match the recorded data. In our paper, we used a stochastic representation of small-scale velocity variability to produce high-frequency scattering and to analyze its implication on shear-motion generation during underground explosions. In our stochasticmore » velocity model, the key parameters that affect scattering are the correlation length and the relative amplitude of velocity perturbations. Finally, based on finite-difference simulations of elastic wave propagation from an isotropic explosion source, we find that higher velocity perturbations result in larger shear motion, whereas the correlation length, which controls the scatterers size, affects the frequency range at which relative transverse motion is larger.« less

  1. Generation of Shear Motion from an Isotropic Explosion Source by Scattering in Heterogeneous Media

    DOE PAGES

    Hirakawa, Evan; Pitarka, Arben; Mellors, Robert

    2016-07-19

    One challenging task in explosion seismology is the development of physical models for explaining the generation of S waves during underground explosions. Recent analysis of ground motion from chemical explosions during the Source Physics Experiment (Pitarka et al., 2015) suggests that, although a large component of shear motion was generated directly at the source, additional scattering from heterogeneous velocity structure and topography is necessary to better match the recorded data. In our paper, we used a stochastic representation of small-scale velocity variability to produce high-frequency scattering and to analyze its implication on shear-motion generation during underground explosions. In our stochasticmore » velocity model, the key parameters that affect scattering are the correlation length and the relative amplitude of velocity perturbations. Finally, based on finite-difference simulations of elastic wave propagation from an isotropic explosion source, we find that higher velocity perturbations result in larger shear motion, whereas the correlation length, which controls the scatterers size, affects the frequency range at which relative transverse motion is larger.« less

  2. A software program to measure the three-dimensional length of the spine from radiographic images: Validation and reliability assessment for adolescent idiopathic scoliosis.

    PubMed

    Berger, Steve; Hasler, Carol-Claudius; Grant, Caroline A; Zheng, Guoyan; Schumann, Steffen; Büchler, Philippe

    2017-01-01

    The aim of this study was to validate a new program which aims at measuring the three-dimensional length of the spine's midline based on two calibrated orthogonal radiographic images. The traditional uniplanar T1-S1 measurement method is not reflecting the actual three dimensional curvature of a scoliotic spine and is therefore not accurate. The Spinal Measurement Software (SMS) is an alternative to conveniently measure the true spine's length. The validity, inter- and intra-observer variability and usability of the program were evaluated. The usability was quantified based on a subjective questionnaire filled by eight participants using the program for the first time. The validity and variability were assessed by comparing the length of five phantom spines measured based on CT-scan data and on radiographic images with the SMS. The lengths were measured independently by each participant using both techniques. The SMS is easy and intuitive to use, even for non-clinicians. The SMS measured spinal length with an error below 2 millimeters compared to length obtained using CT scan datasets. The inter- and intra-observer variability of the SMS measurements was below 5 millimeters. The SMS provides accurate measurement of the spinal length based on orthogonal radiographic images. The software is easy to use and could easily integrate the clinical workflow and replace current approximations of the spinal length based on a single radiographic image such as the traditional T1-S1 measurement. Crown Copyright © 2016. Published by Elsevier Ireland Ltd. All rights reserved.

  3. Regression Analysis of Optical Coherence Tomography Disc Variables for Glaucoma Diagnosis.

    PubMed

    Richter, Grace M; Zhang, Xinbo; Tan, Ou; Francis, Brian A; Chopra, Vikas; Greenfield, David S; Varma, Rohit; Schuman, Joel S; Huang, David

    2016-08-01

    To report diagnostic accuracy of optical coherence tomography (OCT) disc variables using both time-domain (TD) and Fourier-domain (FD) OCT, and to improve the use of OCT disc variable measurements for glaucoma diagnosis through regression analyses that adjust for optic disc size and axial length-based magnification error. Observational, cross-sectional. In total, 180 normal eyes of 112 participants and 180 eyes of 138 participants with perimetric glaucoma from the Advanced Imaging for Glaucoma Study. Diagnostic variables evaluated from TD-OCT and FD-OCT were: disc area, rim area, rim volume, optic nerve head volume, vertical cup-to-disc ratio (CDR), and horizontal CDR. These were compared with overall retinal nerve fiber layer thickness and ganglion cell complex. Regression analyses were performed that corrected for optic disc size and axial length. Area-under-receiver-operating curves (AUROC) were used to assess diagnostic accuracy before and after the adjustments. An index based on multiple logistic regression that combined optic disc variables with axial length was also explored with the aim of improving diagnostic accuracy of disc variables. Comparison of diagnostic accuracy of disc variables, as measured by AUROC. The unadjusted disc variables with the highest diagnostic accuracies were: rim volume for TD-OCT (AUROC=0.864) and vertical CDR (AUROC=0.874) for FD-OCT. Magnification correction significantly worsened diagnostic accuracy for rim variables, and while optic disc size adjustments partially restored diagnostic accuracy, the adjusted AUROCs were still lower. Axial length adjustments to disc variables in the form of multiple logistic regression indices led to a slight but insignificant improvement in diagnostic accuracy. Our various regression approaches were not able to significantly improve disc-based OCT glaucoma diagnosis. However, disc rim area and vertical CDR had very high diagnostic accuracy, and these disc variables can serve to complement additional OCT measurements for diagnosis of glaucoma.

  4. Midupper arm circumference and weight-for-length z scores have different associations with body composition: evidence from a cohort of Ethiopian infants.

    PubMed

    Grijalva-Eternod, Carlos S; Wells, Jonathan C K; Girma, Tsinuel; Kæstel, Pernille; Admassu, Bitiya; Friis, Henrik; Andersen, Gregers S

    2015-09-01

    A midupper arm circumference (MUAC) <115 mm and weight-for-height z score (WHZ) or weight-for-length z score (WLZ) less than -3, all of which are recommended to identify severe wasting in children, often identify different children. The reasons behind this poor agreement are not well understood. We investigated the association between these 2 anthropometric indexes and body composition to help understand why they identify different children as wasted. We analyzed weight, length, MUAC, fat-mass (FM), and fat-free mass (FFM) data from 2470 measurements from 595 healthy Ethiopian infants obtained at birth and at 1.5, 2.5, 3.5, 4.5, and 6 mo of age. We derived WLZs by using 2006 WHO growth standards. We derived length-adjusted FM and FFM values as unexplained residuals after regressing each FM and FFM against length. We used a correlation analysis to assess associations between length, FFM, and FM (adjusted and nonadjusted for length) and the MUAC and WLZ and a multivariable regression analysis to assess the independent variability of length and length-adjusted FM and FFM with either the MUAC or the WLZ as the outcome. At all ages, length showed consistently strong positive correlations with the MUAC but not with the WLZ. Adjustment for length reduced observed correlation coefficients of FM and FFM with the MUAC but increased those for the WLZ. At all ages, both length-adjusted FM and FFM showed an independent association with the WLZ and MUAC with higher regression coefficients for the WLZ. Conversely, length showed greater regression coefficients for the MUAC. At all ages, the MUAC was shown to be more influenced than was the WLZ by the FM variability relative to the FFM variability. The MUAC and WLZ have different associations with body composition, and length influences these associations differently. Our results suggest that the WLZ is a good marker of tissue masses independent of length. The MUAC acts more as a composite index of poor growth indexing jointly tissue masses and length. This trial was registered at www.controlled-trials.com as ISRCTN46718296. © 2015 American Society for Nutrition.

  5. Crystal diffraction lens with variable focal length

    DOEpatents

    Smither, R.K.

    1991-04-02

    A method and apparatus for altering the focal length of a focusing element of one of a plurality of pre-determined focal lengths by changing heat transfer within selected portions of the element by controlled quantities is disclosed. Control over heat transfer is accomplished by manipulating one or more of a number of variables, including: the amount of heat or cold applied to surfaces; type of fluids pumped through channels for heating and cooling; temperatures, directions of flow and rates of flow of fluids; and placement of channels. 19 figures.

  6. Effects of drought season length on live moisture content dynamic in Mediterranean shrubs: 8 years of data

    NASA Astrophysics Data System (ADS)

    Pellizzaro, Grazia; Ventura, Andrea; Bortolu, Sara; Duce, Pierpaolo

    2017-04-01

    Mediterranean shrubs are an important component of Mediterranean vegetation communities. In this kind of vegetation, live fuel is a relevant component of the available fuel which catches fire and, consequently, its water content plays an important role in determining fire occurrence and spread. In live plant, water content patterns are related to both environmental conditions (e.g. meteorological variables, soil water availability) and ecophysiological characteristics of the plant species. According to projections on future climate, an increase in risk of summer droughts is likely to take place in Southern Europe. More prolonged drought seasons induced by climatic changes are likely to influence general flammability characteristics of fuel. In addition, variations in precipitation and mean temperature could directly affect fuel water status and length of critical periods of high ignition danger for Mediterranean ecosystems. The aims of this work were to analyse the influence of both weather seasonality and inter-annual weather variability on live fuel moisture content within and among some common Mediterranean species, and to investigate the effects of prolonged drought season on live moisture content dynamic. The study was carried out in North Sardinia (Italy). Measurements of LFMC seasonal pattern of two really common and flammable Mediterranean shrub species (Cistus monspeliensis and Rosmarinus officinalis) were performed periodically for 8 years. Meteorological variables were also recorded. Relationships between live fuel moisture content and environmental conditions (i.e. rainfall, air temperature and soil moisture) were investigated and effects of different lengths of drought season on LFMC pattern were analysed. Results showed that distribution and amount of rainfall affected seasonal variation of live fuel moisture content. In particular more prolonged drought seasons caused a longer period in which LFMC was below 95 -100% that is commonly considered as critical threshold for fire ignition and spread. This impact was particular evident at the begin of the autumn whereas a limited water availability in spring seemed to have less strongly influenced moisture content in the Mediterranean shrubs that we studied.

  7. Usability of Three-dimensional Augmented Visual Cues Delivered by Smart Glasses on (Freezing of) Gait in Parkinson's Disease.

    PubMed

    Janssen, Sabine; Bolte, Benjamin; Nonnekes, Jorik; Bittner, Marian; Bloem, Bastiaan R; Heida, Tjitske; Zhao, Yan; van Wezel, Richard J A

    2017-01-01

    External cueing is a potentially effective strategy to reduce freezing of gait (FOG) in persons with Parkinson's disease (PD). Case reports suggest that three-dimensional (3D) cues might be more effective in reducing FOG than two-dimensional cues. We investigate the usability of 3D augmented reality visual cues delivered by smart glasses in comparison to conventional 3D transverse bars on the floor and auditory cueing via a metronome in reducing FOG and improving gait parameters. In laboratory experiments, 25 persons with PD and FOG performed walking tasks while wearing custom-made smart glasses under five conditions, at the end-of-dose. For two conditions, augmented visual cues (bars/staircase) were displayed via the smart glasses. The control conditions involved conventional 3D transverse bars on the floor, auditory cueing via a metronome, and no cueing. The number of FOG episodes and percentage of time spent on FOG were rated from video recordings. The stride length and its variability, cycle time and its variability, cadence, and speed were calculated from motion data collected with a motion capture suit equipped with 17 inertial measurement units. A total of 300 FOG episodes occurred in 19 out of 25 participants. There were no statistically significant differences in number of FOG episodes and percentage of time spent on FOG across the five conditions. The conventional bars increased stride length, cycle time, and stride length variability, while decreasing cadence and speed. No effects for the other conditions were found. Participants preferred the metronome most, and the augmented staircase least. They suggested to improve the comfort, esthetics, usability, field of view, and stability of the smart glasses on the head and to reduce their weight and size. In their current form, augmented visual cues delivered by smart glasses are not beneficial for persons with PD and FOG. This could be attributable to distraction, blockage of visual feedback, insufficient familiarization with the smart glasses, or display of the visual cues in the central rather than peripheral visual field. Future smart glasses are required to be more lightweight, comfortable, and user friendly to avoid distraction and blockage of sensory feedback, thus increasing usability.

  8. Atmospheric effects on earth rotation and polar motion

    NASA Technical Reports Server (NTRS)

    Salstein, David A.

    1988-01-01

    The variability in the earth's rotation rate not due to known solid body tides is dominated on time scales of about four years and less by variations in global atmospheric angular momentum (M) as derived from the zonal wind distribution. Among features seen in the length of day record produced by atmospheric forcing are the strong seasonal cycle, quasi-periodic fluctuations around 40-50 days, and an interannual signal forced by a strong Pacific warming event known as the El Nino. Momentum variations associated with these time scales arise in different latitudinal regions. Furthermore, winds in the stratosphere make a particularly important contribution to seasonal variability. Other related topics discussed here are: (1) comparisons of the M series from wind fields produced at different weather centers; (2) the torques that dynamically link the atmosphere and earth; and (3) longer-term nonatmospheric effects that can be seen upon removal of the atmospheric signal.an interestigapplication for climatological purposes is the use of the historical earth rotation series as a proxy for atmospheric wind variability prior to the era of upper-air data. Lastly, results pertaining to the role of atmospheric pressure systems in exciting rapid polar motion are presented.

  9. An 1800-yr record of decadal-scale hydroclimatic variability in the upper Arkansas River basin from bristlecone pine

    USGS Publications Warehouse

    Woodhouse, C.A.; Pederson, G.T.; Gray, S.T.

    2011-01-01

    Bristlecone pine trees are exceptionally long-lived, and with the incorporation of remnant material have been used to construct multi-millennial length ring-width chronologies. These chronologies can provide valuable information about past temperature and moisture variability. In this study, we outline a method to build a moisture-sensitive bristlecone chronology and assess the robustness and consistency of this sensitivity over the past 1200. yr using new reconstructions of Arkansas River flow (AD 1275-2002 and 1577-2002) and the summer Palmer Drought Sensitivity Index. The chronology, a composite built from parts of three collections in the central Rocky Mountains, is a proxy for decadal-scale moisture variability for the past 18 centuries. Since the sample size is small in some portions of the time series, the chronology should be considered preliminary; the timing and duration of drought events are likely the most robust characteristics. This chronology suggests that the region experienced increased aridity during the medieval period, as did much of western North America, but that the timing and duration of drought episodes within this period were somewhat different from those in other western locations, such as the upper Colorado River basin. ?? 2010 University of Washington.

  10. The Role of Lexical Stress on the Use of Vocal Fry in Young Adult Female Speakers.

    PubMed

    Gibson, Todd A

    2017-01-01

    Vocal fry is a voice register often used by young adult women for sociolinguistic purposes. Some acoustic correlates of lexical stress, however, appear incompatible with the use of vocal fry. The objective of this study was to systematically examine the role of lexical stress in the use of vocal fry by young adult women. This is a semi-randomized controlled laboratory study. Fifty female undergraduate students were recorded repeating one-, two-, three-, and four-syllable nonwords that conformed to English phonotactics. Nonwords were presented in order from shorter to longer lengths, with stimuli randomized within syllable length. Perceptual analyses of recordings were augmented by acoustic analyses to identify each syllable in which vocal fry occurred. Eighty-six percent of participants produced at least one episode of vocal fry. Vocal fry was more likely to occur in unstressed than stressed position, and the likelihood increased as distance from the stressed syllable increased. There was considerable variability in the use of vocal fry. Frequent and infrequent users varied on the degree to which they used vocal fry in single-syllable nonwords. Vocal fry use persists among young adult women even in the absence of syntactic and pragmatic influences. Lexical stress appeared to dramatically reduce the use of vocal fry. Patterns of vocal fry use appeared to be different for frequent and infrequent users of this vocal register. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  11. Impact of Intraoperative Steroids on Postoperative Infection Rates and Length of Hospital Stay: A Study of 1200 Spine Surgery Patients.

    PubMed

    Elsamadicy, Aladine A; Wang, Timothy Y; Back, Adam G; Sergesketter, Amanda; Warwick, Hunter; Karikari, Isaac O; Gottfried, Oren N

    2016-12-01

    The use of intraoperative steroids and their effects are relatively unknown and remain controversial. The aim of this study was to determine the effects of intraoperative steroid use on postoperative complications and length of hospital stay after spine surgery. Medical records of 1200 adult patients undergoing spine surgery at Duke University Medical Center during the period 2008-2010 were retrospectively reviewed; 495 (41.25%) patients were administered intraoperative steroids, and 705 (58.75%) patients were not administered intraoperative steroids. Patient demographics, comorbidities, and postoperative complication rates were collected. The primary outcomes investigated were postoperative complications, specifically length of hospital stay and infection rates. Patient demographics were similar between both cohorts. Comorbidities were also similar, with the intraoperative steroid use cohort having a higher number of patients with long-term steroid use than the no intraoperative steroid use cohort (6.95% [no steroids] vs. 13.74% [steroid use], P < 0.001). Operative variables, including length of operation and median number of fusion levels operated, were also similar between the 2 groups. Lumbar spine was the most common surgical location. Patients who were administered intraoperative steroids had a shorter length of hospital stay by an average of 1 day (6.06 days ± 6.76 [no steroids] vs. 5.04 days ± 4.86 [steroid use], P = 0.0025), lower rates of urinary tract infections (10.37% [no steroids] vs. 6.88% [steroid use], P = 0.040), and lower rates of other infections that were not deep or superficial surgical site infections (9.22% [no steroids] vs. 6.06% [steroid use], P = 0.0460). Patients who receive intraoperative steroids have shorter hospital stays and lower infection rates after spine surgery. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Stent sizing strategies in renal artery stenting: the comparison of conventional invasive renal angiography with renal computed tomographic angiography.

    PubMed

    Kadziela, Jacek; Michalowska, Ilona; Pregowski, Jerzy; Janaszek-Sitkowska, Hanna; Lech, Katarzyna; Kabat, Marek; Staruch, Adam; Januszewicz, Andrzej; Witkowski, Adam

    2016-01-01

    Randomized trials comparing invasive treatment of renal artery stenosis with standard pharmacotherapy did not show substantial benefit from revascularization. One of the potential reasons for that may be suboptimal procedure technique. To compare renal stent sizing using two modalities: three-dimensional renal computed tomography angiography (CTA) versus conventional angiography. Forty patients (41 renal arteries), aged 65.1 ±8.5 years, who underwent renal artery stenting with preprocedural CTA performed within 6 months, were retrospectively analyzed. In CTA analysis, reference diameter (CTA-D) and lesion length (CTA_LL) were measured and proposed stent diameter and length were recorded. Similarly, angiographic reference diameter (ANGIO_D) and lesion length (ANGIO_LL) as well as proposed stent dimensions were obtained by visual estimation. The median CTA_D was 0.5 mm larger than the median ANGIO_D (p < 0.001). Also, the proposed stent diameter in CTA evaluation was 0.5 mm larger than that in angiography (p < 0.0001). The median CTA_LL was 1 mm longer than the ANGIO_LL (p = NS), with significant correlation of these variables (r = 0.66, p < 0.0001). The median proposed stent length with CTA was equal to that proposed with angiography. The median diameter of the implanted stent was 0.5 mm smaller than that proposed in CTA (p < 0.0005) and identical to that proposed in angiography. The median length of the actual stent was longer than that proposed in angiography (p = 0.0001). Renal CTA has potential advantages as a tool adjunctive to angiography in appropriate stent sizing. Careful evaluation of the available CTA scans may be beneficial and should be considered prior to the planned procedure.

  13. Stent sizing strategies in renal artery stenting: the comparison of conventional invasive renal angiography with renal computed tomographic angiography

    PubMed Central

    Michalowska, Ilona; Pregowski, Jerzy; Janaszek-Sitkowska, Hanna; Lech, Katarzyna; Kabat, Marek; Staruch, Adam; Januszewicz, Andrzej; Witkowski, Adam

    2016-01-01

    Introduction Randomized trials comparing invasive treatment of renal artery stenosis with standard pharmacotherapy did not show substantial benefit from revascularization. One of the potential reasons for that may be suboptimal procedure technique. Aim To compare renal stent sizing using two modalities: three-dimensional renal computed tomography angiography (CTA) versus conventional angiography. Material and methods Forty patients (41 renal arteries), aged 65.1 ±8.5 years, who underwent renal artery stenting with preprocedural CTA performed within 6 months, were retrospectively analyzed. In CTA analysis, reference diameter (CTA-D) and lesion length (CTA_LL) were measured and proposed stent diameter and length were recorded. Similarly, angiographic reference diameter (ANGIO_D) and lesion length (ANGIO_LL) as well as proposed stent dimensions were obtained by visual estimation. Results The median CTA_D was 0.5 mm larger than the median ANGIO_D (p < 0.001). Also, the proposed stent diameter in CTA evaluation was 0.5 mm larger than that in angiography (p < 0.0001). The median CTA_LL was 1 mm longer than the ANGIO_LL (p = NS), with significant correlation of these variables (r = 0.66, p < 0.0001). The median proposed stent length with CTA was equal to that proposed with angiography. The median diameter of the implanted stent was 0.5 mm smaller than that proposed in CTA (p < 0.0005) and identical to that proposed in angiography. The median length of the actual stent was longer than that proposed in angiography (p = 0.0001). Conclusions Renal CTA has potential advantages as a tool adjunctive to angiography in appropriate stent sizing. Careful evaluation of the available CTA scans may be beneficial and should be considered prior to the planned procedure. PMID:27279870

  14. Do position and size matter? An analysis of cage and placement variables for optimum lordosis in PLIF reconstruction.

    PubMed

    Landham, Priyan R; Don, Angus S; Robertson, Peter A

    2017-11-01

    To examine monosegmental lordosis after posterior lumbar interbody fusion (PLIF) surgery and relate lordosis to cage size, shape, and placement. Eighty-three consecutive patients underwent single-level PLIF with paired identical lordotic cages involving a wide decompression and bilateral facetectomies. Cage parameters relating to size (height, lordosis, and length) and placement (expressed as a ratio relative to the length of the inferior vertebral endplate) were recorded. Centre point ratio (CPR) was the distance to the centre of both cages and indicated mean position of both cages. Posterior gap ratio (PGR) was the distance to the most posterior cage and indicated position and cage length indirectly. Relationships between lordosis and cage parameters were explored. Mean lordosis increased by 5.98° (SD 6.86°). The cages used varied in length from 20 to 27 mm, in lordosis from 10° to 18°, and in anterior cage height from 10 to 17 mm. The mean cage placement as determined by CPR was 0.54 and by PGR was 0.16. The significant correlations were: both CPR and PGR with lordosis gain at surgery (r = 0.597 and 0.537, respectively, p < 0.001 both), cage lordosis with the final lordosis (r = 0.234, p < 0.05), and anterior cage height was negatively correlated with a change in lordosis (r = -0.297, p < 0.01). Cage size, shape, and position, in addition to surgical technique, determine lordosis during PLIF surgery. Anterior placement with sufficient "clear space" behind the cages is recommended. In addition, cages should be of moderate height and length, so that they act as an effective pivot for lordosis.

  15. Genetic architecture, inter-relationship and selection criteria for yield improvement in rice (Oryza sativa L.).

    PubMed

    Yadav, S K; Pandey, P; Kumar, B; Suresh, B G

    2011-05-01

    This study has been conducted to determine the extent of genetic association between yield of Rice (Oryza sativa L.) and its components. The present experiment was carried out with 40 Rice (Oryza sativa L.) genotypes which were evaluated in a randomized block design with 3 replications during wet season of 2007 and 2008. Results showed that sufficient amount of variability was found in the entire gene pool for all traits studied. Higher magnitude of genotypic and phenotypic coefficients of variation was recorded for seed yield, harvest index, biological yield, number of spikelets per panicle, flag leaf length, plant height and number of tillers indicates that these characters are least influence by environment. High heritability coupled with high genetic advance as percent of mean was registered for seed yield, harvest index, number of spikelets per panicle, biological yield and flag leaf length, suggesting preponderance of additive gene action in the expression of these characters. Grain yield was significantly and positively associated with harvest index, number of tillers per hill, number of panicle per plant, panicle length, number of spikelet's per panicle and test weight at both genotypic and phenotypic levels. Path coefficient analysis revealed that harvest index, biological yield, number of tillers per hill, panicle length, number of spikelets per panicle, plant height and test weight had direct positive effect on seed yield, indicating these are the main contributors to yield. From this study it may be concluded that harvest index, number of tillers per hill, panicle length and number of spikelet per panicle and test weight are the most important characters that contributed directly to yield. Thus, these characters may serve selection criteria for improving genetic potential of rice.

  16. Dust Emission Modeling Incorporating Land Cover Parameterizations in the Chihuahuan Desert and Dissemination of Data Suites

    NASA Astrophysics Data System (ADS)

    Olgin, J. G.; Pennington, D. D.; Webb, N.

    2017-12-01

    A variety of models have been developed to better understand dust emissions - from initial erosive event to entrainment to transport through the atmosphere. Many of these models have been used to analyze dust emissions by representing atmospheric and surface variables, such as wind and soil moisture respectively, in a numerical model to determine the resulting dust emissions. Pertinent to modeling these variables, there are three important factors influencing emissions: 1) Friction velocity threshold based on wind interactions with dust, 2) horizontal flux (saltation) of dust and 3) vertical dust flux. While all of the existing models incorporate these processes, additional improvements are needed to yield results reflective of recorded data of dust events. Our investigation focuses on explicitly identifying specific land cover (LC) elements unique to the Chihuahan desert that contribute to aerodynamic roughness length (Zo); a main component to dust emission and key to provide results more representative of known dust events in semi-arid regions. These elements will be formulated into computer model inputs by conducting analysis (e.g. geostatistics) on field and satellite data to ascertain core LC characteristics responsible for affecting wind velocities (e.g. wind shadowing effects), which are conducive to dust emissions. This inputs will be used in a modified program using the Weather and Research Forecast model (WRF) to replicate previously recorded dust events. Results from this study will be presented here.

  17. Age-specific vibrissae growth rates: a tool for determining the timing of ecologically important events in Steller sea lions

    USGS Publications Warehouse

    Rea, L.D.; Christ, A.M.; Hayden, A.B.; Stegall, V.K.; Farley, S.D.; Stricker, Craig A.; Mellish, J.E.; Maniscalco, John M.; Waite, J.N.; Burkanov, V.N.; Pitcher, K.W.

    2015-01-01

    Steller sea lions (SSL; Eumetopias jubatus) grow their vibrissae continually, providing a multiyear record suitable for ecological and physiological studies based on stable isotopes. An accurate age-specific vibrissae growth rate is essential for registering a chronology along the length of the record, and for interpreting the timing of ecologically important events. We utilized four methods to estimate the growth rate of vibrissae in fetal, rookery pup, young-of-the-year (YOY), yearling, subadult, and adult SSL. The majority of vibrissae were collected from SSL live-captured in Alaska and Russia between 2000 and 2013 (n = 1,115), however, vibrissae were also collected from six adult SSL found dead on haul-outs and rookeries during field excursions to increase the sample size of this underrepresented age group. Growth rates of vibrissae were generally slower in adult (0.44 ± 0.15 cm/mo) and subadult (0.61 ± 0.10 cm/mo) SSL than in YOY (0.87 ± 0.28 cm/mo) and fetal (0.73 ± 0.05 cm/mo) animals, but there was high individual variability in these growth rates within each age group. Some variability in vibrissae growth rates was attributed to the somatic growth rate of YOY sea lions between capture events (P = 0.014, r2 = 0.206, n = 29).

  18. An 800-Year Record of Sediment-Derived, Instrumentally-Calibrated Foraminiferal Mg/Ca SST Estimates From the Tropical North Atlantic

    NASA Astrophysics Data System (ADS)

    Black, D. E.; Abahazi, M. A.; Thunell, R. C.; Tappa, E. J.

    2005-12-01

    Most geochemical paleoclimate proxies are calibrated to different climate variables using laboratory culture, surface sediment, or sediment trap experiments. The varved, high-deposition rate sediments of the Cariaco Basin (Venezuela) provide the nearly unique opportunity to compare and calibrate paleoceanographic proxy data directly against true oceanic historical instrumental climate records. Here we present one of the first sediment-derived foraminiferal-Mg/Ca to SST calibrations spanning A. D. 1870-1990. The record of Mg/Ca-estimated tropical North Atlantic SSTs is then extended back to approximately A. D. 1200. Box core PL07-73 BC, recovered from the northeastern slope of Cariaco Basin, was sampled at consecutive 1 mm increments and processed for foraminiferal population, stable isotope, and Mg/Ca (by ICP-AES) analyses. The age model for this core was established by correlating faunal population records from PL07-73 to a nearby very well-dated Cariaco Basin box core, PL07-71 BC. The resulting age model yields consecutive sample intervals of one to two years. Mg/Ca ratios measured on Globigerina bulloides in samples deposited between A. D. 1870 and 1990 were calibrated to monthly SSTs from the Met Office Hadley Centre's SST data set for the Cariaco Basin grid square. Annual correlations between G. bulloides Mg/Ca and instrumental SST were highest (r=0.6, p<.0001, n=120) for the months of March, April, and May, the time when sediment trap studies indicate G. bulloides is most abundant in the basin. The full-length Mg/Ca-estimated SST record is characterized by decadal- and centennial-scale variability. The tropical western North Atlantic does not appear to have experienced a pronounced Medieval Warm Period relative to the complete record. However, strong Little Ice Age cooling of as much as 3 ° C occurred between A. D. 1525 and 1625. Spring SSTs gradually rose between A. D. 1650 and 1900 followed by a 2.5 ° C warming over the 20th century.

  19. Last interglacial temperature seasonality reconstructed from tropical Atlantic corals

    NASA Astrophysics Data System (ADS)

    Felis, T.; Brocas, W.; Obert, J. C.; Gierz, P.; Lohmann, G.; Scholz, D.; Kölling, M.; Pfeiffer, M.; Scheffers, S. R.

    2016-12-01

    Reconstructions of last interglacial ( 127-117 ka) climate offer insights into the natural response and variability of the climate system during a period partially analogous to future climate change scenarios. However, the seasonal temperature changes of the tropical ocean are not well known for the last interglacial period. Here we present well preserved fossil corals (Diploria strigosa) recovered from the southern Caribbean island of Bonaire. These corals have been precisely dated by the 230Th/U-method to between 130 and 118 ka ago. Annual banding of the coral skeleton enabled construction of time windows of monthly resolved Sr/Ca temperature proxy records. Our eight coral records of up to 37 years in length cover a total of 105 years within the last interglacial period. From these coral records, sea surface temperature (SST) seasonality in the tropical North Atlantic Ocean is reconstructed. We detect similar to modern SST seasonality of 2.9 °C during the early (130 ka) and the late last interglacial (120 - 118 ka). However, within the mid-last interglacial, a significantly higher than modern SST seasonality of 4.9 °C (at 126 ka) and 4.1 °C (at 124 ka) is observed. These findings are supported by climate model simulations (COSMOS) and are consistent with the evolving amplitude of orbitally induced changes in seasonality of insolation throughout the last interglacial, irrespective of wider climatic instabilities that characterised this period, e.g. at 118 ka ago. The climate model simulations suggest that the SST seasonality changes documented in our last interglacial coral Sr/Ca records are representative of larger regions within the tropical North Atlantic. These simulations also suggest that the reconstructed SST seasonality increase during the mid-last interglacial is caused primarily by summer warming. Furthermore, a 124 ka old coral documents evidence of decadal SST variability in the tropical North Atlantic during the last interglacial, akin to that observed in modern instrumental records. Our results indicate that the dense theca walls of brain coral skeletons (e.g., Diploria strigosa) can provide robust seasonally resolved proxy records of tropical SST and reliable 230Th/U-ages for the last interglacial period.

  20. The average direct current offset values for small digital audio recorders in an acoustically consistent environment.

    PubMed

    Koenig, Bruce E; Lacey, Douglas S

    2014-07-01

    In this research project, nine small digital audio recorders were tested using five sets of 30-min recordings at all available recording modes, with consistent audio material, identical source and microphone locations, and identical acoustic environments. The averaged direct current (DC) offset values and standard deviations were measured for 30-sec and 1-, 2-, 3-, 6-, 10-, 15-, and 30-min segments. The research found an inverse association between segment lengths and the standard deviation values and that lengths beyond 30 min may not meaningfully reduce the standard deviation values. This research supports previous studies indicating that measured averaged DC offsets should only be used for exclusionary purposes in authenticity analyses and exhibit consistent values when the general acoustic environment and microphone/recorder configurations were held constant. Measured average DC offset values from exemplar recorders may not be directly comparable to those of submitted digital audio recordings without exactly duplicating the acoustic environment and microphone/recorder configurations. © 2014 American Academy of Forensic Sciences.

  1. Evaluating the Risk of Re-identification of Patients from Hospital Prescription Records.

    PubMed

    Emam, Khaled El; Dankar, Fida K; Vaillancourt, Régis; Roffey, Tyson; Lysyk, Mary

    2009-07-01

    Pharmacies often provide prescription records to private research firms, on the assumption that these records are de-identified (i.e., identifying information has been removed). However, concerns have been expressed about the potential that patients can be re-identified from such records. Recently, a large private research firm requested prescription records from the Children's Hospital of Eastern Ontario (CHEO), as part of a larger effort to develop a database of hospital prescription records across Canada. To evaluate the ability to re-identify patients from CHEO'S prescription records and to determine ways to appropriately de-identify the data if the risk was too high. The risk of re-identification was assessed for 18 months' worth of prescription data. De-identification algorithms were developed to reduce the risk to an acceptable level while maintaining the quality of the data. The probability of patients being re-identified from the original variables and data set requested by the private research firm was deemed quite high. A new de-identified record layout was developed, which had an acceptable level of re-identification risk. The new approach involved replacing the admission and discharge dates with the quarter and year of admission and the length of stay in days, reporting the patient's age in weeks, and including only the first character of the patient's postal code. Additional requirements were included in the data-sharing agreement with the private research firm (e.g., audit requirements and a protocol for notification of a breach of privacy). Without a formal analysis of the risk of re-identification, assurances of data anonymity may not be accurate. A formal risk analysis at one hospital produced a clinically relevant data set that also protects patient privacy and allows the hospital pharmacy to explicitly manage the risks of breach of patient privacy.

  2. Does Receiving a Blood Transfusion Predict for Length of Stay in Children Undergoing Cranial Vault Remodeling for Craniosynostosis? Outcomes Using the Pediatric National Surgical Quality Improvement Program Dataset.

    PubMed

    Markiewicz, Michael R; Alden, Tord; Momin, Mohmed Vasim; Olsson, Alexis B; Jurado, Ray J; Abdullah, Fizan; Miloro, Michael

    2017-08-01

    Recent interventions have aimed at reducing the need for blood transfusions in the perioperative period in patients with craniosynostosis undergoing cranial vault remodeling. However, little is known regarding whether the receipt of a blood transfusion influences the length of hospital stay. The purpose of this study was to assess whether the receipt of a blood transfusion in patients undergoing cranial vault remodeling is associated with an increased length of stay. To address the research purposes, we designed a retrospective cohort study using the 2014 Pediatric National Surgical Quality Improvement Program (NSQIP Peds) dataset. The primary predictor variable was whether patients received a blood transfusion during cranial vault remodeling. The primary outcome variable was length of hospital stay after the operation. The association between the receipt of blood transfusions and length of stay was assessed using the Student t test. The association between other covariates and the outcome variable was assessed using linear regression, analysis of variance, and the Tukey test for post hoc pair-wise comparisons. The sample was composed of 756 patients who underwent cranial vault remodeling: 503 who received blood transfusions and 253 who did not. The primary predictor variable of blood transfusion was associated with an increased length of stay (4.1 days vs 3.0 days, P = .03). Other covariates associated with an increased length of stay included race, American Society of Anesthesiologists status, premature birth, presence of a congenital malformation, and number of sutures involved in craniosynostosis. The receipt of a blood transfusion in the perioperative period in patients with craniosynostosis undergoing cranial vault remodeling was associated with an increased length of stay. Copyright © 2017 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  3. Convergence of leaf display and photosynthetic characteristics of understory Abies amabilis and Tsuga Heterophylla in an old-growth forest in southwestern Washington State, USA

    Treesearch

    Hiroaki Ishii; Ken-Ichi Yoshimura; Akira Mori

    2009-01-01

    The branching pattern of A. amabilis was regular (normal shoot-length distribution, less variable branching angle and bifurcation ratio), whereas that of T. heterophylla was more plastic (positively skewed shoot-length distribution, more variable branching angle and bifurcation ratio). The two species had similar shoot...

  4. Does Foot Anthropometry Predict Metabolic Cost During Running?

    PubMed

    van Werkhoven, Herman; Piazza, Stephen J

    2017-10-01

    Several recent investigations have linked running economy to heel length, with shorter heels being associated with less metabolic energy consumption. It has been hypothesized that shorter heels require larger plantar flexor muscle forces, thus increasing tendon energy storage and reducing metabolic cost. The goal of this study was to investigate this possible mechanism for metabolic cost reduction. Fifteen male subjects ran at 16 km⋅h -1 on a treadmill and subsequently on a force-plate instrumented runway. Measurements of oxygen consumption, kinematics, and ground reaction forces were collected. Correlational analyses were performed between oxygen consumption and anthropometric and kinetic variables associated with the ankle and foot. Correlations were also computed between kinetic variables (peak joint moment and peak tendon force) and heel length. Estimated peak Achilles tendon force normalized to body weight was found to be strongly correlated with heel length normalized to body height (r = -.751, p = .003). Neither heel length nor any other measured or calculated variable were correlated with oxygen consumption, however. Subjects with shorter heels experienced larger Achilles tendon forces, but these forces were not associated with reduced metabolic cost. No other anthropometric and kinetic variables considered explained the variance in metabolic cost across individuals.

  5. Three-dimensional Procrustes analysis of modern human craniofacial form.

    PubMed

    Badawi-Fayad, Jackie; Cabanis, Emmanuel-Alain

    2007-03-01

    The objective of this study was to analyze modern human craniofacial form using 3D Procrustes superimposition in order to establish a reference model and validate it on computed tomography (CT). The sample consists of 136 specimens from five modern human regional groups. Thirty-three craniofacial landmark coordinates have been recorded using a Microscribe and calculated on CT scans for five crania from the sample. Procrustes superimposition has been performed to calculate the mean shape, and a discriminant analysis has also been carried out to estimate the variability of shape. The results show that the repeatability of measurements made on CT and on Microscribe is excellent (R = 0.99). There is no major distinctiveness in the craniofacial shape; however, discriminant function 1 separates out the European crania from the others, especially African and American. It includes the width and the length of the face, the flatness of the upper face, the prognathism of the maxilla, as well as the length and the inclination of the palate. The width of the maxilla and the palate do not show a great variability. This may be the common invariant feature responsible for the alignment of the teeth in all specimens. It may correspond to functional patterns related to masticatory constraints manifested by the important interproximal and occlusal dental wear in all specimens. This study confirms the high accuracy of measurements made on CT scan and the importance of geometric morphometrics, which provides an accurate characterization of the overall craniofacial shape and its variation within the entire population.

  6. Changes in step-width during dual-task walking predicts falls.

    PubMed

    Nordin, E; Moe-Nilssen, R; Ramnemark, A; Lundin-Olsson, L

    2010-05-01

    The aim was to evaluate whether gait pattern changes between single- and dual-task conditions were associated with risk of falling in older people. Dual-task cost (DTC) of 230 community living, physically independent people, 75 years or older, was determined with an electronic walkway. Participants were followed up each month for 1 year to record falls. Mean and variability measures of gait characteristics for 5 dual-task conditions were compared to single-task walking for each participant. Almost half (48%) of the participants fell at least once during follow-up. Risk of falling increased in individuals where DTC for performing a subtraction task demonstrated change in mean step-width compared to single-task walking. Risk of falling decreased in individuals where DTC for carrying a cup and saucer demonstrated change compared to single-task walking in mean step-width, mean step-time, and step-length variability. Degree of change in gait characteristics related to a change in risk of falling differed between measures. Prognostic guidance for fall risk was found for the above DTCs in mean step-width with a negative likelihood ratio of 0.5 and a positive likelihood ratio of 2.3, respectively. Findings suggest that changes in step-width, step-time, and step-length with dual tasking may be related to future risk of falling. Depending on the nature of the second task, DTC may indicate either an increased risk of falling, or a protective strategy to avoid falling. Copyright 2010. Published by Elsevier B.V.

  7. Decadal climate variability and the spatial organization of deep hydrological drought

    NASA Astrophysics Data System (ADS)

    Barros, Ana P.; Hodes, Jared L.; Arulraj, Malarvizhi

    2017-10-01

    Empirical Orthogonal Function (EOF), wavelet, and wavelet coherence analysis of baseflow time-series from 126 streamgauges (record-length > 50 years; small and mid-size watersheds) in the US South Atlantic (USSA) region reveal three principal modes of space-time variability: (1) a region-wide dominant mode tied to annual precipitation that exhibits non-stationary decadal variability after the mid 1990s concurrent with the warming of the AMO (Atlantic Multidecadal Oscillation); (2) two spatial modes, east and west of the Blue Ridge, exhibiting nonstationary seasonal to sub-decadal variability before and after 1990 attributed to complex nonlinear interactions between ENSO and AMO impacting precipitation and recharge; and (3) deep (decadal) and shallow (< 6 years) space-time modes of groundwater variability separating basins with high and low annual mean baseflow fraction (MBF) by physiographic region. The results explain the propagation of multiscale climate variability into the regional groundwater system through recharge modulated by topography, geomorphology, and geology to determine the spatial organization of baseflow variability at decadal (and longer) time-scales, that is, deep hydrologic drought. Further, these findings suggest potential for long-range predictability of hydrological drought in small and mid-size watersheds, where baseflow is a robust indicator of nonstationary yield capacity of the underlying groundwater basins. Predictive associations between climate mode indices and deep baseflow (e.g. persistent decreases of the decadal-scale components of baseflow during the cold phase of the AMO in the USSA) can be instrumental toward improving forecast lead-times and long-range mitigation of severe drought.

  8. Statistical models for estimating daily streamflow in Michigan

    USGS Publications Warehouse

    Holtschlag, D.J.; Salehi, Habib

    1992-01-01

    Statistical models for estimating daily streamflow were analyzed for 25 pairs of streamflow-gaging stations in Michigan. Stations were paired by randomly choosing a station operated in 1989 at which 10 or more years of continuous flow data had been collected and at which flow is virtually unregulated; a nearby station was chosen where flow characteristics are similar. Streamflow data from the 25 randomly selected stations were used as the response variables; streamflow data at the nearby stations were used to generate a set of explanatory variables. Ordinary-least squares regression (OLSR) equations, autoregressive integrated moving-average (ARIMA) equations, and transfer function-noise (TFN) equations were developed to estimate the log transform of flow for the 25 randomly selected stations. The precision of each type of equation was evaluated on the basis of the standard deviation of the estimation errors. OLSR equations produce one set of estimation errors; ARIMA and TFN models each produce l sets of estimation errors corresponding to the forecast lead. The lead-l forecast is the estimate of flow l days ahead of the most recent streamflow used as a response variable in the estimation. In this analysis, the standard deviation of lead l ARIMA and TFN forecast errors were generally lower than the standard deviation of OLSR errors for l < 2 days and l < 9 days, respectively. Composite estimates were computed as a weighted average of forecasts based on TFN equations and backcasts (forecasts of the reverse-ordered series) based on ARIMA equations. The standard deviation of composite errors varied throughout the length of the estimation interval and generally was at maximum near the center of the interval. For comparison with OLSR errors, the mean standard deviation of composite errors were computed for intervals of length 1 to 40 days. The mean standard deviation of length-l composite errors were generally less than the standard deviation of the OLSR errors for l < 32 days. In addition, the composite estimates ensure a gradual transition between periods of estimated and measured flows. Model performance among stations of differing model error magnitudes were compared by computing ratios of the mean standard deviation of the length l composite errors to the standard deviation of OLSR errors. The mean error ratio for the set of 25 selected stations was less than 1 for intervals l < 32 days. Considering the frequency characteristics of the length of intervals of estimated record in Michigan, the effective mean error ratio for intervals < 30 days was 0.52. Thus, for intervals of estimation of 1 month or less, the error of the composite estimate is substantially lower than error of the OLSR estimate.

  9. Estimating moisture content of tree-length roundwood

    Treesearch

    Alexander Clark; Richard F. Daniels

    2000-01-01

    The green weight of southern pine tree-length roundwood delivered to the pulp mill is generally known. However, for optimum mill efficiency it is desirable to know dry weight. The moisture content of tree-length pine logs is quite variable. The moisture content of pine tree-length logs increases significantly with increasing stem height. Moisture content also varies...

  10. Phenotypic plasticity of Vaccinium meridionale (Ericaceae) in wild populations of mountain forests in Colombia.

    PubMed

    Ligarreto, Gustavo A; Patiño, Maria del Pilar; Magnitskiy, Stanislav V

    2011-06-01

    Vaccinium meridionale is a promising crop for the Andean region of South America and is currently available only in the wild. Spontaneous populations of this plant are found across the Colombian mountains, but very few published records on this plant morphology are available. A zonification study of V. meridionale was conducted in four principal areas of a low mountain forest of Colombia (Provinces of Boyacá, Cundinamarca, Santander and Nariño) in 2007. A total of 20 populations and 100 plants of V. meridionale were individually characterized and surveyed, using a list of 26 characters of morphological variables (9 quantitative and 17 qualitative characters). Our results indicated that natural populations of V. meridionale might be found in the tropical forest under a highly heterogeneous climate and microclimate conditions, at different mountain regions between 2 357 and 3 168masl. The shrubs of V. meridionale exhibited a high level of intra-population variation in several quantitative (plant height, stem diameter) and qualitative (growth habit, ramification density, presence of anthocyanins in stems) morphological characters, suggesting an environmentally induced phenotypic plasticity. Plant height, stem diameter and foliar density were the most variable morphological traits, with coefficients of variation higher than 50%. However, several quantitative characters of its reproductive potential, such as berry dimensions, rachis length and number of flowers per inflorescence, resulted with low plasticity with coefficients of variation lower than 30.2%, indicating that these characters were genetically determined. The highest correlation coefficients (p < 0.05) resulted to be between fruit length and fruit width (0.90), leaf length and leaf width (0.78), plant height and stem diameter (0.60), and inflorescence length and flowers number per inflorescence (0.57). The results suggest that an important genetic resource exists for this species in the wild. Low variation in fruit size, which constitutes a target trait for plant breeders, could be useful for selection of cultivars of V. meridionale. The results of this study could also be applied in conservation programs aimed to protect these diverse populations in the mountain forests of Colombia.

  11. The Nomogram of Penile Length and Circumference in Iranian Term and Preterm Neonates.

    PubMed

    Soheilipour, Fahimeh; Rohani, Farzaneh; Dehkordi, Elham Hashemi; Isa Tafreshi, Roya; Mohagheghi, Parisa; Zaheriani, Seyed-Mohammadsalar; Jesmi, Fatemeh; Salehiniya, Hamid

    2018-01-01

    The normal length of penis in preterm and term neonates is different among different nations, and is affected by various factors. The present study aimed to determine stretched penile length (SPL) values and cutoff level of micropenis in term and preterm Iranian neonates, for the first time. All male neonates born in two general hospitals of Tehran (Akbarabadi, and Rasoul hospitals), center of Iran, with gestational age of 28-42 weeks were included and their SPL and penile circumference (PC) were examined on the first 3 days after birth by the same physician. Birth weight (BW), and height, gestational age, type of delivery, mother's age, twin/multiple pregnancy, drug, and medical history of mother during pregnancy were recorded and cutoff levels of two variables were calculated based on the collected variables for different gestational ages. Among a total of 587 neonates, 203 neonates were born term and 384 preterm. Mean ± SD of neonates' BW were 2,682.51 ± 739.30 (850-4800) gr. Mean ± SD of their SPL was 22.48 ± 3.34 mm; 25.92 ± 1.54 mm in term and 20.66 ± 2.50 mm in preterm infants ( P  = 0.001). Mean ± SD of PC was 6.71 ± 1.31 mm; 8.14 ± 0.48 in term and 5.96 ± 0.92 in preterm infants ( P  = 0.001). SPL and PC were significantly correlated with type of delivery, number of parity, gestational age, BW, and crown-heel length, head circumference ( P  < 0.001). This study suggested that SPL in male neonates was 22.48 mm and PC was 6.71 mm, both correlated with gestational age and BW. Due to the ethnical variety of this cutoff points and lack of an appropriate study in Iran, these cutoff points can be used by all physicians as a reference for Iranian newborns (term and preterm), in order to prevent misdiagnosis of micropenis and genital disorders.

  12. On Short-Time Estimation of Vocal Tract Length from Formant Frequencies

    PubMed Central

    Lammert, Adam C.; Narayanan, Shrikanth S.

    2015-01-01

    Vocal tract length is highly variable across speakers and determines many aspects of the acoustic speech signal, making it an essential parameter to consider for explaining behavioral variability. A method for accurate estimation of vocal tract length from formant frequencies would afford normalization of interspeaker variability and facilitate acoustic comparisons across speakers. A framework for considering estimation methods is developed from the basic principles of vocal tract acoustics, and an estimation method is proposed that follows naturally from this framework. The proposed method is evaluated using acoustic characteristics of simulated vocal tracts ranging from 14 to 19 cm in length, as well as real-time magnetic resonance imaging data with synchronous audio from five speakers whose vocal tracts range from 14.5 to 18.0 cm in length. Evaluations show improvements in accuracy over previously proposed methods, with 0.631 and 1.277 cm root mean square error on simulated and human speech data, respectively. Empirical results show that the effectiveness of the proposed method is based on emphasizing higher formant frequencies, which seem less affected by speech articulation. Theoretical predictions of formant sensitivity reinforce this empirical finding. Moreover, theoretical insights are explained regarding the reason for differences in formant sensitivity. PMID:26177102

  13. Improved Fast, Deep Record Length, Time-Resolved Visible Spectroscopy of Plasmas Using Fiber Grids

    NASA Astrophysics Data System (ADS)

    Brockington, S.; Case, A.; Cruz, E.; Williams, A.; Witherspoon, F. D.; Horton, R.; Klauser, R.; Hwang, D.

    2017-10-01

    HyperV Technologies is developing a fiber-coupled, deep record-length, low-light camera head for performing high time resolution spectroscopy on visible emission from plasma events. By coupling the output of a spectrometer to an imaging fiber bundle connected to a bank of amplified silicon photomultipliers, time-resolved spectroscopic imagers of 100 to 1,000 pixels can be constructed. A second generation prototype 32-pixel spectroscopic imager employing this technique was constructed and successfully tested at the University of California at Davis Compact Toroid Injection Experiment (CTIX). Pixel performance of 10 Megaframes/sec with record lengths of up to 256,000 frames ( 25.6 milliseconds) were achieved. Pixel resolution was 12 bits. Pixel pitch can be refined by using grids of 100 μm to 1000 μm diameter fibers. Experimental results will be discussed, along with future plans for this diagnostic. Work supported by USDOE SBIR Grant DE-SC0013801.

  14. Fast, Deep-Record-Length, Fiber-Coupled Photodiode Imaging Array for Plasma Diagnostics

    NASA Astrophysics Data System (ADS)

    Brockington, Samuel; Case, Andrew; Witherspoon, F. Douglas

    2015-11-01

    HyperV Technologies has been developing an imaging diagnostic comprised of an array of fast, low-cost, long-record-length, fiber-optically-coupled photodiode channels to investigate plasma dynamics and other fast, bright events. By coupling an imaging fiber bundle to a bank of amplified photodiode channels, imagers and streak imagers can be constructed. By interfacing analog photodiode systems directly to commercial analog-to-digital converters and modern memory chips, a scalable solution for 100 to 1000 pixel systems with 14 bit resolution and record-lengths of 128k frames has been developed. HyperV is applying these techniques to construct a prototype 1000 Pixel framing camera with up to 100 Msamples/sec rate and 10 to 14 bit depth. Preliminary experimental results as well as future plans will be discussed. Work supported by USDOE Phase 2 SBIR Grant DE-SC0009492.

  15. Fast, Deep-Record-Length, Fiber-Coupled Photodiode Imaging Array for Plasma Diagnostics

    NASA Astrophysics Data System (ADS)

    Brockington, Samuel; Case, Andrew; Witherspoon, F. Douglas

    2014-10-01

    HyperV Technologies has been developing an imaging diagnostic comprised of an array of fast, low-cost, long-record-length, fiber-optically-coupled photodiode channels to investigate plasma dynamics and other fast, bright events. By coupling an imaging fiber bundle to a bank of amplified photodiode channels, imagers and streak imagers of 100 to 1000 pixels can be constructed. By interfacing analog photodiode systems directly to commercial analog-to-digital converters and modern memory chips, a prototype 100 pixel array with an extremely deep record length (128 k points at 20 Msamples/s) and 10 bit pixel resolution has already been achieved. HyperV now seeks to extend these techniques to construct a prototype 1000 Pixel framing camera with up to 100 Msamples/sec rate and 10 to 12 bit depth. Preliminary experimental results as well as Phase 2 plans will be discussed. Work supported by USDOE Phase 2 SBIR Grant DE-SC0009492.

  16. Phase and vortex correlations in superconducting Josephson-junction arrays at irrational magnetic frustration.

    PubMed

    Granato, Enzo

    2008-07-11

    Phase coherence and vortex order in a Josephson-junction array at irrational frustration are studied by extensive Monte Carlo simulations using the parallel-tempering method. A scaling analysis of the correlation length of phase variables in the full equilibrated system shows that the critical temperature vanishes with a power-law divergent correlation length and critical exponent nuph, in agreement with recent results from resistivity scaling analysis. A similar scaling analysis for vortex variables reveals a different critical exponent nuv, suggesting that there are two distinct correlation lengths associated with a decoupled zero-temperature phase transition.

  17. Low-frequency centroid-moment-tensor inversion from superconducting-gravimeter data: The effect of seismic attenuation

    NASA Astrophysics Data System (ADS)

    Zábranová, Eliška; Matyska, Ctirad

    2014-10-01

    After the 2010 Maule and 2011 Tohoku earthquakes the spheroidal modes up to 1 mHz were clearly registered by the Global Geodynamic Project (GGP) network of superconducting gravimeters (SG). Fundamental parameters in synthetic calculations of the signals are the quality factors of the modes. We study the role of their uncertainties in the centroid-moment-tensor (CMT) inversions. First, we have inverted the SG data from selected GGP stations to jointly determine the quality factors of these normal modes and the three low-frequency CMT components, Mrr,(Mϑϑ-Mφφ)/2 and Mϑφ, that generate the observed SG signal. We have used several-days-long records to minimize the trade-off between the quality factors and the CMT but it was not eliminated completely. We have also inverted each record separately to get error estimates of the obtained parameters. Consequently, we have employed the GGP records of 60-h lengths for several published modal-quality-factor sets and inverted only the same three CMT components. The obtained CMT tensors are close to the solution from the joint Q-CMT inversion of longer records and resulting variability of the CMT components is smaller than differences among routine agency solutions. Reliable low-frequency CMT components can thus be obtained for any quality factors from the studied sets.

  18. Effect of altering starting length and activation timing of muscle on fiber strain and muscle damage.

    PubMed

    Butterfield, Timothy A; Herzog, Walter

    2006-05-01

    Muscle strain injuries are some of the most frequent injuries in sports and command a great deal of attention in an effort to understand their etiology. These injuries may be the culmination of a series of subcellular events accumulated through repetitive lengthening (eccentric) contractions during exercise, and they may be influenced by a variety of variables including fiber strain magnitude, peak joint torque, and starting muscle length. To assess the influence of these variables on muscle injury magnitude in vivo, we measured fiber dynamics and joint torque production during repeated stretch-shortening cycles in the rabbit tibialis anterior muscle, at short and long muscle lengths, while varying the timing of activation before muscle stretch. We found that a muscle subjected to repeated stretch-shortening cycles of constant muscle-tendon unit excursion exhibits significantly different joint torque and fiber strains when the timing of activation or starting muscle length is changed. In particular, measures of fiber strain and muscle injury were significantly increased by altering activation timing and increasing the starting length of the muscle. However, we observed differential effects on peak joint torque during the cyclic stretch-shortening exercise, as increasing the starting length of the muscle did not increase torque production. We conclude that altering activation timing and muscle length before stretch may influence muscle injury by significantly increasing fiber strain magnitude and that fiber dynamics is a more important variable than muscle-tendon unit dynamics and torque production in influencing the magnitude of muscle injury.

  19. Upper lip changes and gingival exposure on smiling: vertical dimension analysis.

    PubMed

    Miron, Hagai; Calderon, Shlomo; Allon, Dror

    2012-01-01

    Our objectives were to evaluate and quantify upper lip soft-tissue changes in the vertical dimensions both at rest and at maximum smile, and to examine the correlation between upper labial vestibular attachment height and maxillary gingival exposure on smiling. Seventy-two volunteers (36 men, 36 women) aged 20 to 40 (mean, 30.49 years) were recruited for this study. For each subject, 9 measurements of upper lip position and maxillary incisor crown height at rest and in maximum smile were recorded. A statistically significant sexual dimorphism was apparent in most of the measured variables. Relaxed external upper lip length was 3.1 mm shorter in the women than in the men. The mean maxillary central incisor display at rest was 1.78 mm greater in the women than in the men. A high smile line was 2.5 times more prevalent in the women. The upper lip was shortened by 30% in subjects with a high smile line compared with 23% in subjects with a low smile line. The following findings were observed in subjects with a high smile pattern: (1) short upper lip length, (2) low smiling/resting upper lip length ratio, (3) inferior attachment of the upper labial vestibule, and (4) prominent upper lip vermilion. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  20. Blood cultures in emergency medical admissions: a key patient cohort.

    PubMed

    Chotirmall, Sanjay H; Callaly, Elizabeth; Lyons, Judith; O'Connell, Brian; Kelleher, Mary; Byrne, Declan; O'Riordan, Deirdre; Silke, Bernard

    2016-02-01

    Blood cultures are performed in the emergency room when sepsis is suspected, and a cohort of patients is thereby identified. The present study investigated the outcomes (mortality and length of hospital stay) in this group following an emergency medical admission. Prospective assessment of all emergency medical admissions presenting to the emergency department at St James's Hospital, Dublin, over an 11-year period (2002-2012) was carried out. Outcomes including 30-day in-hospital mortality and length of stay were explored in the context of an admission blood culture. Generalized estimating equations, logistic or zero-truncated Poisson multivariate models were used, with adjustment for confounding variables including illness severity, comorbidity, and chronic disabling disease, to assess the effect of an urgent blood culture on mortality and length of stay. A total of 60 864 episodes were recorded in 35 168 patients admitted over the time period assessed. Patients more likely to undergo blood cultures in the emergency department were male, younger, and had more comorbidity. Univariate and multivariate analyses showed that those who had a blood culture, irrespective of result, had increased mortality and a longer in-hospital stay. This was highest for those with a positive culture, irrespective of the organism isolated. A clinical decision to request a blood culture identified a subset of emergency admissions with markedly worse outcomes. This patient cohort warrants close monitoring in the emergency setting.

  1. Demographic indicators of change in a deposit-feeding abyssal holothurian community (Station M, 4000 m)

    NASA Astrophysics Data System (ADS)

    Huffard, Christine L.; Kuhnz, Linda A.; Lemon, Larissa; Sherman, Alana D.; Smith, Kenneth L.

    2016-03-01

    Holothurians are among the most abundant benthic megafauna at abyssal depths, and important consumers and bioturbators of organic carbon on the sea floor. Significant fluctuations in abyssal holothurian density are often attributed to species-specific responses to variable particulate organic carbon flux (food supply) stemming from surface ocean events. We report changes in densities of 19 holothurian species at the abyssal monitoring site Station M in the northeast Pacific, recorded during 11 remotely operated vehicle surveys between Dec 2006 and Oct 2014. Body size demographics are presented for Abyssocucumis abyssorum, Synallactidae sp. 1, Paelopatides confundens, Elpidia sp. A, Peniagone gracilis, Peniagone papillata, Peniagone vitrea, Peniagone sp. A, Peniagone sp. 1, and Scotoplanes globosa. Densities were lower and species evenness was higher from 2006-2009 compared to 2011-2014. Food supply of freshly-settled phytodetritus was exceptionally high during this latter period. Based on relationships between median body length and density, numerous immigration and juvenile recruitment events of multiple species appeared to take place between 2011 and 2014. These patterns were dominated by elpidiids (Holothuroidea: Elasipodida: Elpidiidae), which consistently increased in density during a period of high food availability, while other groups showed inconsistent responses. We considered minimum body length to be a proxy for size at juvenile recruitment. Patterns in density clustered by this measure, which was a stronger predictor of maximum density than median and mean body length.

  2. Comparative sacral morphology and the reconstructed tail lengths of five extinct primates: Proconsul heseloni, Epipliopithecus vindobonensis, Archaeolemur edwardsi, Megaladapis grandidieri, and Palaeopropithecus kelyus.

    PubMed

    Russo, Gabrielle A

    2016-01-01

    This study evaluated the relationship between the morphology of the sacrum-the sole bony link between the tail or coccyx and the rest of the body-and tail length (including presence/absence) and function using a comparative sample of extant mammals spanning six orders (Primates, Carnivora, Rodentia, Diprotodontia, Pilosa, Scandentia; N = 472). Phylogenetically-informed regression methods were used to assess how tail length varied with respect to 11 external and internal (i.e., trabecular) bony sacral variables with known or suspected biomechanical significance across all mammals, only primates, and only non-primates. Sacral variables were also evaluated for primates assigned to tail categories ('tailless,' 'nonprehensile short-tailed,' 'nonprehensile long-tailed,' and 'prehensile-tailed'). Compared to primates with reduced tail lengths, primates with longer tails generally exhibited sacra having larger caudal neural openings than cranial neural openings, and last sacral vertebrae with more mediolaterally-expanded caudal articular surfaces than cranial articular surfaces, more laterally-expanded transverse processes, more dorsally-projecting spinous processes, and larger caudal articular surface areas. Observations were corroborated by the comparative sample, which showed that shorter-tailed (e.g., Lynx rufus [bobcat]) and longer-tailed (e.g., Acinonyx jubatus [cheetah]) non-primate mammals morphologically converge with shorter-tailed (e.g., Macaca nemestrina) and longer-tailed (e.g., Macaca fascicularis) primates, respectively. 'Prehensile-tailed' primates exhibited last sacral vertebrae with more laterally-expanded transverse processes and greater caudal articular surface areas than 'nonprehensile long-tailed' primates. Internal sacral variables performed poorly compared to external sacral variables in analyses of extant primates, and were thus deemed less useful for making inferences concerning tail length and function in extinct primates. The tails lengths of five extinct primates were reconstructed from the external sacral variables: Archaeolemur edwardsi had a 'nonprehensile long tail,' Megaladapis grandidieri, Palaeopropithecus kelyus, and Epipliopithecus vindobonensis probably had 'nonprehensile short tails,' and Proconsul heseloni was 'tailless.' Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Millennial-scale variability in Holocene aquatic productivity from Burial Lake, Arctic Alaska

    NASA Astrophysics Data System (ADS)

    Finkenbinder, Matthew S.; Abbott, Mark B.; Stoner, Joseph S.; Ortiz, Joseph D.; Finney, Bruce P.; Dorfman, Jason M.; Stansell, Nathan D.

    2018-05-01

    Holocene records of lacustrine primary production are commonly used to reconstruct past changes in environmental and climatic conditions. While several methods exist to infer paleoproductivity trends, few studies to date have applied multiple geochemical indices in the same core sequence from Arctic lakes to evaluate their fidelity and sensitivity to specific climate variables over long (Holocene length) timescales. In this study, we evaluate sub-century to millennial-scale fluctuations in paleoproductivity over the Holocene using geochemical (biogenic opal and sedimentary chlorin) analyses of sediments from Burial Lake in the western Brooks Range, Alaska. Large fluctuations in opal and related proxies occur at millennial timescales over the last 10,000 years. We interpret the changes in opal to result from variability in diatom productivity, which is indirectly mediated by climate primarily through changes in the duration of the ice-free growing season and the availability of limiting nutrients at this oligotrophic, tundra lake. Comparison of the opal and sedimentary chlorin record, which is correlated with TOC, shows contrasting patterns on both short (century to multi-century) and relatively long (millennial) time scales. The concentration of opal far exceeds that of TOC and variations in sediment dry bulk density, driven by changes in the accumulation of opal, are likely responsible in part for the variations in sedimentary chlorin. Further, C/N ratio values indicate a mixed algal-terrestrial source of sedimentary organic matter. This result highlights the complexity in the climatic interpretation of sedimentary chlorin as an index of whole lake production, because the signal is prone to dilution/concentration from opal and also reflects a combination of aquatic and terrestrial production. Time series analysis of the productivity records indicates the presence of a significant ∼1500-yr oscillation in opal concentration, which has been found in North Atlantic Ocean proxy records and numerous other marine and terrestrial paleorecords. Comparison of diatom productivity against a sea-ice inferred reconstruction of the Arctic Oscillation (AO) from the Beaufort Sea (Darby et al., 2012) shows that periods of reduced productivity at Burial Lake coincide with inferred positive phases of the AO (AO+). Combined with modern observations of sea ice extent and meteorological data, we hypothesize that AO + conditions and a strengthened polar jet correspond with a shortened ice-free growing season, a decrease in the availability of limiting nutrients, and lower levels of diatom production at Burial Lake. Comparison of the spectral properties between opal and the AO reconstruction reveal similar millennial scale variations with ∼1500-yr variability during the middle Holocene that transition to ∼1000-yr variability during the late Holocene. In light of these findings, we suggest the possibility that millennial variations in diatom productivity observed in the Burial Lake record are related to millennial variability in high-latitude atmospheric circulation similar to the AO. These results shed light on the sensitivity of aquatic ecosystems in northern Alaska to changes in the duration of the ice-free growing season, the availability of limiting nutrients for phytoplankton growth, and Arctic-wide atmospheric circulation dynamics over the Holocene on millennial timescales.

  4. Does Tagging Improve the Navigation of Online Recorded Lectures by Students?

    ERIC Educational Resources Information Center

    Gorissen, Pierre; van Bruggen, Jan; Jochems, Wim

    2015-01-01

    Students more and more have access to online recordings of the lectures they attend at universities. The volume and length of these recorded lectures however make them difficult to navigate. Research shows that students primarily watch the recorded lectures while preparing for their exams. They do watch the full recorded lectures, but review only…

  5. Length of residence and risk of eating disorders in immigrant adolescents living in madrid. The AFINOS study.

    PubMed

    Esteban-Gonzalo, Laura; Veiga, Oscar L; Gómez-Martínez, Sonia; Veses, Ana M; Regidor, Enrique; Martínez, David; Marcos, Ascensión; Calle, María E

    2014-05-01

    This study was designed to compare the risk of having an eating disorder (ED) among immigrant and native adolescents living in Madrid and to determine the possible influence of length of residence (LOR) on the risk of the immigrants. A cross-sectional survey was conducted from november 2007 to february 2008 in a representative sample of adolescents aged 13 to 17 years (n = 2,077, 1,052 girls) living in the Madrid region. Data were collected using the Spanish version of the SCOFF Eating Disorders Questionnaire. Further factors considered were country of birth, LOR and several biological, sociodemographic, lifestyle and health-related variables. According to the three logistic regression models constructed, female immigrant adolescents on the whole showed a greater ED risk (OR = 1.95; 95% CI 1.29- 2.95; p = 0.001) than native adolescents. Moreover, the likelihood of ED was higher among female immigrants living in Spain for <6 years than for Spanish native females (OR = 2.44; 95% CI 1.42-4.18; p = 0.001), while no significant differences were found when female natives were compared with female immigrants living in this country for ≥ 6 years. Similarly, no differences were observed in the ED risk recorded for male native and immigrant adolescents, both as a whole and by length of residence in Spain. The immigrant status and the length of Spanish residence are relevant factors in regard to the ED risk in adolescents living in Madrid. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  6. LUR models for particulate matters in the Taipei metropolis with high densities of roads and strong activities of industry, commerce and construction.

    PubMed

    Lee, Jui-Huna; Wu, Chang-Fu; Hoek, Gerard; de Hoogh, Kees; Beelen, Rob; Brunekreef, Bert; Chan, Chang-Chuan

    2015-05-01

    Traffic intensity, length of road, and proximity to roads are the most common traffic indicators in the land use regression (LUR) models for particulate matter in ESCAPE study areas in Europe. This study explored what local variables can improve the performance of LUR models in an Asian metropolis with high densities of roads and strong activities of industry, commerce and construction. By following the ESCAPE procedure, we derived LUR models of PM₂.₅, PM₂.₅ absorbance, PM₁₀, and PMcoarse (PM₂.₅-₁₀) in Taipei. The overall annual average concentrations of PM₂.₅, PM₁₀, and PMcoarse were 26.0 ± 5.6, 48.6 ± 5.9, and 23.3 ± 3.1 μg/m(3), respectively, and the absorption coefficient of PM₂.₅ was 2.0 ± 0.4 × 10(-5)m(-1). Our LUR models yielded R(2) values of 95%, 96%, 87%, and 65% for PM₂.₅, PM₂.₅ absorbance, PM₁₀, and PMcoarse, respectively. PM₂.₅ levels were increased by local traffic variables, industrial, construction, and residential land-use variables and decreased by rivers; while PM₂.₅ absorbance levels were increased by local traffic variables, industrial, and commercial land-use variables in the models. PMcoarse levels were increased by elevated highways. Road area explained more variance than road length by increasing the incremental value of 27% and 6% adjusted R(2) for PM₂.₅ and PM₁₀ models, respectively. In the PM₂.₅ absorbance model, road area and transportation facility explain 29% more variance than road length. In the PMcoarse model, industrial and new local variables instead of road length improved the incremental value of adjusted R(2) from 39% to 60%. We concluded that road area can better explain the spatial distribution of PM₂.₅ and PM₂.₅ absorbance concentrations than road length. By incorporating road area and other new local variables, the performance of each PM LUR model was improved. The results suggest that road area is a better indicator of traffic intensity rather than road length in a city with high density of road network and traffic. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Egg number-egg size: an important trade-off in parasite life history strategies.

    PubMed

    Cavaleiro, Francisca I; Santos, Maria J

    2014-03-01

    Parasites produce from just a few to many eggs of variable size, but our understanding of the factors driving variation in these two life history traits at the intraspecific level is still very fragmentary. This study evaluates the importance of performing multilevel analyses on egg number and egg size, while characterising parasite life history strategies. A total of 120 ovigerous females of Octopicola superba (Copepoda: Octopicolidae) (one sample (n=30) per season) were characterised with respect to different body dimensions (total length; genital somite length) and measures of reproductive effort (fecundity; mean egg diameter; total reproductive effort; mean egg sac length). While endoparasites are suggested to follow both an r- and K-strategy simultaneously, the evidence found in this and other studies suggests that environmental conditions force ectoparasites into one of the two alternatives. The positive and negative skewness of the distributions of fecundity and mean egg diameter, respectively, suggest that O. superba is mainly a K-strategist (i.e. produces a relatively small number of large, well provisioned eggs). Significant sample differences were recorded concomitantly for all body dimensions and measures of reproductive effort, while a general linear model detected a significant influence of season*parasite total length in both egg number and size. This evidence suggests adaptive phenotypic plasticity in body dimensions and size-mediated changes in egg production. Seasonal changes in partitioning of resources between egg number and size resulted in significant differences in egg sac length but not in total reproductive effort. Evidence for a trade-off between egg number and size was found while controlling for a potential confounding effect of parasite total length. However, this trade-off became apparent only at high fecundity levels, suggesting a state of physiological exhaustion. Copyright © 2014 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.

  8. Revisiting the utility of technical performance scores following tetralogy of Fallot repair.

    PubMed

    Lodin, Daud; Mavrothalassitis, Orestes; Haberer, Kim; Sunderji, Sherzana; Quek, Ruben G W; Peyvandi, Shabnam; Moon-Grady, Anita; Karamlou, Tara

    2017-08-01

    Although an important quality metric, current technical performance scores may not be generalizable and may omit operative factors that influence outcomes. We examined factors not included in current technical performance scores that may contribute to increased postoperative length of stay, major complications, and cost after primary repair of tetralogy of Fallot. This is a retrospective single site study of patients younger than age 2 years with tetralogy of Fallot undergoing complete repair between 2007 and 2015. Medical record data and discharge echocardiograms were reviewed to ascertain component and composite technical performance scores. Primary outcomes included postoperative length of stay, major complications, and total hospital costs. Multivariable logistic and linear regression identified determinants of each outcome. Patient population (n = 115) had a median postoperative length of stay of 8 days (interquartile range, 6-10 days), and a median total cost of $71,147. Major complications occurred in 33 patients (29%) with 1 death. Technical performance scores assigned were optimum in 28 patients (25%), adequate in 59 patients (52%), and inadequate in 26 patients (23%). Neither technical performance score components nor composite scores were associated with increased postoperative length of stay. Optimum or adequate repairs versus inadequate had equal risk of a complication (P = .79), and equivalent mean total cost ($100,000 vs $187,000; P = .25). Longer cardiopulmonary bypass time per 1-minute increase (P < .01) was associated with longer postoperative length of stay and reintervention (P = .02). The need to return to bypass also increased total cost (P < .01). Current tetralogy of Fallot technical performance scores were not associated with selected outcomes in our postoperative population. Although returning to bypass and bypass length are not included as components in the current score, these are important factors influencing complications and resource use in our population. Revisions anticipated from a prospective trial should consider including these variables. Copyright © 2017 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

  9. Convergent and Divergent Validity of the Grammaticality and Utterance Length Instrument

    ERIC Educational Resources Information Center

    Castilla-Earls, Anny; Fulcher-Rood, Katrina

    2018-01-01

    Purpose: This feasibility study examines the convergent and divergent validity of the Grammaticality and Utterance Length Instrument (GLi), a tool designed to assess the grammaticality and average utterance length of a child's prerecorded story retell. Method: Three raters used the GLi to rate audio-recorded story retells from 100 English-speaking…

  10. Simulating Spatial Variability of Fluvial Sediment Fluxes Within the Magdalena Drainage Basin, Colombia.

    NASA Astrophysics Data System (ADS)

    Kettner, A. J.; Syvitski, J. P.; Restrepo, J. D.

    2008-12-01

    This study explores the application of an empirical sediment flux model BQART, to simulate long-term sediment fluxes of major tributaries of a river system based on a limited number of input parameters. We validate model results against data of the 1612 km long Magdalena River, Colombia, South America, which is well monitored. The Magdalena River, draining a hinterland area of 257,438 km2, of which the majority lies in the Andes before reaching the Atlantic coast, is known for its high sediment yield, 560 t kg- 2 yr-1; higher than nearby South American rivers like the Amazon or the Orinoco River. Sediment fluxes of 32 tributary basins of the Magdalena River were simulated based on the following controlling factors: geomorphic influences (tributary-basin area and relief) derived from high-resolution Shuttle Radar Topography Mission data, tributary basin-integrated lithology based on GIS analysis of lithology data, 30year temperature data, and observed monthly mean discharge data records (varying in record length of 15 to 60 years). Preliminary results indicate that the simulated sediment flux of all 32 tributaries matches the observational record, given the observational error and the annual variability. These simulations did not take human influences into account yet, which often increases sediment fluxes by accelerating erosion, especially in steep mountainous area similar to the Magdalena. Simulations indicate that, with relatively few input parameters, mostly derived from remotely-sensed data or existing compiled GIS datasets, it is possible to predict: which tributaries in an arbitrary river drainage produce relatively high contributions to sediment yields, and where in the drainage basin you might expect conveyance loss.

  11. Assessment of gait in subcortical vascular encephalopathy by computerized analysis: a cross-sectional and longitudinal study.

    PubMed

    Bäzner, H; Oster, M; Daffertshofer, M; Hennerici, M

    2000-11-01

    In subcortical vascular encephalopathy (SVE) gait disturbance is a common and early clinical sign which might be used to monitor disease progression. In the absence of reliable scales and with regard to the equivocal results of highly complex gait imaging devices we assessed the natural course of SVE in a prospective study, using a new straight forward technique to quantify and compare sequential gait studies. We report the results of 300 computerized gait analyses in 119 patients with SVE and 63 age-matched controls. Thirty-nine SVE patients were re-evaluated to monitor the natural course of the disease and to study the correlation of gait disturbances with MRI changes and neuropsychological findings. The system consists of a set of shoes containing 16 load sensors and a measuring-unit reading each sensor at 20-ms intervals. By off-line analysis we graded each recording on a Gait Disorder Score (GDS) with six variables indicating gait steadiness: step frequency, length of gait lines (which represent the movement of the centre of gravity during heel to toe movement), length of single support lines, variability of single and of double support lines, and double support time. In cross-sectional analysis, patients with SVE showed cadence (steps/min) to be reduced at 87.3 +/- 19.5 (96.4 +/- 7.8 in controls, P < 0.05). Length of gait lines was significantly less: 0.70 +/- 0.13 vs. 0.80 +/- 0.05 in controls, with length of single support gait lines reduced at 0.42 +/- 0.14 in SVE (0.58 +/- 0.06 in controls, P < 0.05). Variability of both single support lines (5.69 +/- 1.90%; 4.24 +/- 1.07% in controls, P < 0.05) and double support lines was elevated (3.59 +/- 1.62% vs. 2.54 +/- 0.59%), while duration of double support phases was increased (0.19 +/- 0.10 s vs. 0.13 +/- 0.02 s in controls, P < 0.05). The progressive character of the disease was demonstrated by increasing GDS values in 39 SVE patients with a frontal gait disorder who were re-investigated after a mean interval of 26 months (5.4 +/- 4.5 vs. 8.4 +/- 5.5, P < 0.05). This study shows the value of a new and practicable gait analysis system for the evaluation of gait disorders and it quantifies the deterioration of gait in SVE patients.

  12. Realizing the Translational Potential of Telomere Length Variation as a Tissue-Based Prognostic Marker for Prostate Cancer

    DTIC Science & Technology

    2014-10-01

    Telomere Length Variation as a Tissue- Based Prognostic Marker for Prostate Cancer PRINCIPAL INVESTIGATOR: Elizabeth A. Platz CONTRACTING...Translational Potential of Telomere Length Variation as a Tissue- Based Prognostic Marker for Prostate Cancer 5b. GRANT NUMBER W81XWH-12-1-0545 5c...combination of telomere length variability in prostate cancer cells and short telomere length in cancer-associated stromal cells is an independent

  13. Late Holocene Hydroclimate Variability of West-Central Guatemala Driven by NAO and ENSO

    NASA Astrophysics Data System (ADS)

    Stansell, N.; Feller, J. R.; Steinman, B. A.; Lachniet, M. S.; Shea, C.; Avendaño, C.

    2016-12-01

    Finely-laminated sediments from Lake San Francisco in the Huehuetenango province of west-central Guatemala provide a sub-decadal resolution record of hydroclimate variability spanning the last 5200 years. Age control is based on 7 radiocarbon samples of charcoal and lead-210 dating of surface sediments. Modern water isotope samples indicate the lake is currently an open system, and variations of δ18O values of precipitation in the region are driven largely by the amount effect. In contrast, a strong covariance of δ18O and δ13C values combined with pollen evidence in the lower part of the record suggests the lake was a seasonally closed-basin from 5200 to 3200 BP, and was sensitive to evaporation under more arid conditions. There was an overall trend of increasingly wetter conditions during the late Holocene, and a lack of covariance between δ18O and δ13C indicates that the lake transitioned to an open-basin after 3200 BP. The Medieval Climate Anomaly was the wettest period of the late Holocene, and there was a shift to lower precipitation amounts during the Little Ice Age. Present conditions are more arid than most of the last millennium, but δ18O values in the modern sediments are intermediate compared to the full late Holocene. The Lake San Francisco record provides additional evidence that the hydroclimate of Central America is sensitive to both changes in North Atlantic Oscillation (NAO) and the El Niño Southern Oscillation (ENSO). Drier conditions at San Francisco over the length of the record were associated with more negative phases of NAO and vice versa. During the last 1500 years, drier conditions at San Francisco were also associated with warmer sea-surface temperatures (SSTs) in the Niño3 region, and it was wetter when SSTs were colder.

  14. Estimating radiative feedbacks from stochastic fluctuations in surface temperature and energy imbalance

    NASA Astrophysics Data System (ADS)

    Proistosescu, C.; Donohoe, A.; Armour, K.; Roe, G.; Stuecker, M. F.; Bitz, C. M.

    2017-12-01

    Joint observations of global surface temperature and energy imbalance provide for a unique opportunity to empirically constrain radiative feedbacks. However, the satellite record of Earth's radiative imbalance is relatively short and dominated by stochastic fluctuations. Estimates of radiative feedbacks obtained by regressing energy imbalance against surface temperature depend strongly on sampling choices and on assumptions about whether the stochastic fluctuations are primarily forced by atmospheric or oceanic variability (e.g. Murphy and Forster 2010, Dessler 2011, Spencer and Braswell 2011, Forster 2016). We develop a framework around a stochastic energy balance model that allows us to parse the different contributions of atmospheric and oceanic forcing based on their differing impacts on the covariance structure - or lagged regression - of temperature and radiative imbalance. We validate the framework in a hierarchy of general circulation models: the impact of atmospheric forcing is examined in unforced control simulations of fixed sea-surface temperature and slab ocean model versions; the impact of oceanic forcing is examined in coupled simulations with prescribed ENSO variability. With the impact of atmospheric and oceanic forcing constrained, we are able to predict the relationship between temperature and radiative imbalance in a fully coupled control simulation, finding that both forcing sources are needed to explain the structure of the lagged-regression. We further model the dependence of feedback estimates on sampling interval by considering the effects of a finite equilibration time for the atmosphere, and issues of smoothing and aliasing. Finally, we develop a method to fit the stochastic model to the short timeseries of temperature and radiative imbalance by performing a Bayesian inference based on a modified version of the spectral Whittle likelihood. We are thus able to place realistic joint uncertainty estimates on both stochastic forcing and radiative feedbacks derived from observational records. We find that these records are, as of yet, too short to be useful in constraining radiative feedbacks, and we provide estimates of how the uncertainty narrows as a function of record length.

  15. Autonomic cardiac regulation during spontaneous nocturnal hypoglycemia in patients with type 1 diabetes.

    PubMed

    Koivikko, Minna L; Tulppo, Mikko P; Kiviniemi, Antti M; Kallio, Mika A; Perkiömäki, Juha S; Salmela, Pasi I; Airaksinen, K E Juhani; Huikuri, Heikki V

    2012-07-01

    Experimental clamp studies have suggested that hypoglycemia evokes a reduction of cardiac vagal control in patients with type 1 diabetes. However, there are limited data on the influence of spontaneous nocturnal hypoglycemia on cardiac autonomic regulation. Adults with type 1 diabetes (n = 37) underwent continuous glucose monitoring via a subcutaneous sensor as well as recording of R-R interval or electrocardiogram for 3 nights. Heart rate (HR) variability was analyzed during periods of hypoglycemia (glucose <3.5 mmol/L) (minimum length of 20 min) and a control nonhypoglycemic period (glucose >3.9 mmol/L) of equal duration and at the same time of night. The duration of hypoglycemic and control episodes (n = 18) ranged from 20 to 190 min (mean 71 min). HR (62 ± 7 vs. 63 ± 9 beats per min; P = 0.30) or the high-frequency component of HR power spectrum (2,002 ± 1,965 vs. 1,336 ± 1,506 ms(2); P = 0.26) did not change during hypoglycemia. Hypoglycemia resulted in a significant decrease in the low-frequency component of HR variability (2,134 ± 1,635 vs. 1,169 ± 1,029 ms(2), respectively; P = 0.006). The decline in the glucose concentration displayed a significant positive correlation with the decrease of the low-frequency component of HR variability (r = 0.48; P = 0.04). The latter was closely related to an increase in muscle sympathetic nerve activity recorded in 10 subjects during controlled sympathetic activation. Spontaneous nocturnal hypoglycemia in patients with type 1 diabetes results in a reduction of the low-frequency component of HR, which is best explained by excessive sympathetic activation without a concomitant withdrawal of vagal outflow.

  16. Explaining Direct Care Resource Use of Nursing Home Residents: Findings from Time Studies in Four States

    PubMed Central

    Arling, Greg; Kane, Robert L; Mueller, Christine; Lewis, Teresa

    2007-01-01

    Objective To explain variation in direct care resource use (RU) of nursing home residents based on the Resource Utilization Groups III (RUG-III) classification system and other resident- and unit-level explanatory variables. Data Sources/Study Setting Primary data were collected on 5,314 nursing home residents in 156 nursing units in 105 facilities from four states (CO, IN, MN, MS) from 1998 to 2004. Study Design Nurses and other direct care staff recorded resident-specific and other time caring for all residents on sampled nursing units. Care time was linked to resident data from the Minimum Data Set assessment instrument. Major variables were: RUG-III group (34-group), other health and functional conditions, licensed and other professional minutes per day, unlicensed minutes per day, and direct care RU (wage-weighted minutes). Resident- and unit-level relationships were examined through hierarchical linear modeling. Data Collection/Extraction Methods Time study data were recorded with hand-held computers, verified for accuracy by project staff at the data collection sites and then merged into resident and unit-level data sets. Principal Findings Resident care time and RU varied between and within nursing units. RUG-III group was related to RU; variables such as length of stay and unit percentage of high acuity residents also were significantly related. Case-mix indices (CMIs) constructed from study data displayed much less variation across RUG-III groups than CMIs from earlier time studies. Conclusions Results from earlier time studies may not be representative of care patterns of Medicaid and private pay residents. New RUG-III CMIs should be developed to better reflect the relative costs of caring for these residents. PMID:17362220

  17. Statistical modelling for precision agriculture: A case study in optimal environmental schedules for Agaricus Bisporus production via variable domain functional regression.

    PubMed

    Panayi, Efstathios; Peters, Gareth W; Kyriakides, George

    2017-01-01

    Quantifying the effects of environmental factors over the duration of the growing process on Agaricus Bisporus (button mushroom) yields has been difficult, as common functional data analysis approaches require fixed length functional data. The data available from commercial growers, however, is of variable duration, due to commercial considerations. We employ a recently proposed regression technique termed Variable-Domain Functional Regression in order to be able to accommodate these irregular-length datasets. In this way, we are able to quantify the contribution of covariates such as temperature, humidity and water spraying volumes across the growing process, and for different lengths of growing processes. Our results indicate that optimal oxygen and temperature levels vary across the growing cycle and we propose environmental schedules for these covariates to optimise overall yields.

  18. Statistical modelling for precision agriculture: A case study in optimal environmental schedules for Agaricus Bisporus production via variable domain functional regression

    PubMed Central

    Panayi, Efstathios; Kyriakides, George

    2017-01-01

    Quantifying the effects of environmental factors over the duration of the growing process on Agaricus Bisporus (button mushroom) yields has been difficult, as common functional data analysis approaches require fixed length functional data. The data available from commercial growers, however, is of variable duration, due to commercial considerations. We employ a recently proposed regression technique termed Variable-Domain Functional Regression in order to be able to accommodate these irregular-length datasets. In this way, we are able to quantify the contribution of covariates such as temperature, humidity and water spraying volumes across the growing process, and for different lengths of growing processes. Our results indicate that optimal oxygen and temperature levels vary across the growing cycle and we propose environmental schedules for these covariates to optimise overall yields. PMID:28961254

  19. The Effects of Music Salience on the Gait Performance of Young Adults.

    PubMed

    de Bruin, Natalie; Kempster, Cody; Doucette, Angelica; Doan, Jon B; Hu, Bin; Brown, Lesley A

    2015-01-01

    The presence of a rhythmic beat in the form of a metronome tone or beat-accentuated original music can modulate gait performance; however, it has yet to be determined whether gait modulation can be achieved using commercially available music. The current study investigated the effects of commercially available music on the walking of healthy young adults. Specific aims were (a) to determine whether commercially available music can be used to influence gait (i.e., gait velocity, stride length, cadence, stride time variability), (b) to establish the effect of music salience on gait (i.e., gait velocity, stride length, cadence, stride time variability), and (c) to examine whether music tempi differentially effected gait (i.e., gait velocity, stride length, cadence, stride time variability). Twenty-five participants walked the length of an unobstructed walkway while listening to music. Music selections differed with respect to the salience or the tempo of the music. The genre of music and artists were self-selected by participants. Listening to music while walking was an enjoyable activity that influenced gait. Specifically, salient music selections increased measures of cadence, velocity, and stride length; in contrast, gait was unaltered by the presence of non-salient music. Music tempo did not differentially affect gait performance (gait velocity, stride length, cadence, stride time variability) in these participants. Gait performance was differentially influenced by music salience. These results have implications for clinicians considering the use of commercially available music as an alternative to the traditional rhythmic auditory cues used in rehabilitation programs. © the American Music Therapy Association 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. South American Monsoon variability during the past 2,000 years from stable isotopic proxies and model simulations

    NASA Astrophysics Data System (ADS)

    Vuille, M.; Cruz, F. W.; Abbott, M.; Bird, B. W.; Burns, S. J.; Cheng, H.; Colose, C. M.; Kanner, L. C.; LeGrande, A. N.; Novello, V. F.; Taylor, B. L.

    2012-12-01

    The rapidly growing number of high-resolution stable isotopic proxies from speleothems, ice cores and lake sediments, located in the South American summer monsoon (SASM) belt, will soon allow for a comprehensive analysis of climate variability in the South American tropics and subtropics over the past ~ 2000 years. In combination with isotope-enabled General Circulation Models (GCMs) this offers new prospects for better understanding the spatiotemporal dynamics of the South American monsoon system and for diagnosing its sensitivities to external forcing mechanisms (solar, volcanic) and modes of ocean-atmosphere variability (e.g. ENSO and AMO). In this presentation we will discuss the rationale for interpreting isotopic excursions recorded in various proxies from the Andes, northeastern and southeastern Brazil as indicative of changes in monsoon intensity. We will focus on the past 2 millenia when isotopic proxies from the SASM region show a very coherent behavior regardless of the type of archive or their location. All proxies exhibit significant decadal to multidecadal variability, superimposed on large excursions during three key periods, the Medieval Climate Anomaly (MCA), the Little Ice Age (LIA) and the Current Warm Period (CWP). We interpret these three periods as times when the SASM mean state was significantly weakened (MCA and CWP) and strengthened (LIA), respectively. During the LIA each of the proxy archives considered contains the most negative delta-18O values recorded during the entire record length. On the other hand the monsoon strength is currently rather weak in a 2000- year historical perspective, rivaled only by the low intensity during the MCA. One interpretation of these centennial-scale climate anomalies suggests that they were at least partially driven by temperature changes in the northern hemisphere and in particular over the North Atlantic, leading to a latitudinal displacement of the ITCZ and a change in monsoon intensity and degree of rainout upstream of the proxy locations, over the tropical continent. This interpretation is supported by several independent proxy archives and modeling studies. One question that remains, however, is how ENSO, arguably the main forcing factor for delta-18O variability over tropical South America on interannual time scales, interacts with and may be modulated by low-frequency North Atlantic forcing. Our analysis also implies that isotopic proxies, because of their ability to integrate climatic information on large spatial scales, are complementary to more traditional proxies such as tree rings or historical archives, which record in-situ climate variations. Future climate reconstructions therefore should make an effort to include isotopic proxies as large-scale predictors in order to better constrain past changes in the atmospheric circulation.

  1. Record Charge Carrier Diffusion Length in Colloidal Quantum Dot Solids via Mutual Dot-To-Dot Surface Passivation.

    PubMed

    Carey, Graham H; Levina, Larissa; Comin, Riccardo; Voznyy, Oleksandr; Sargent, Edward H

    2015-06-03

    Through a combination of chemical and mutual dot-to-dot surface passivation, high-quality colloidal quantum dot solids are fabricated. The joint passivation techniques lead to a record diffusion length for colloidal quantum dots of 230 ± 20 nm. The technique is applied to create thick photovoltaic devices that exhibit high current density without losing fill factor. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Combining Fourier and lagged k-nearest neighbor imputation for biomedical time series data.

    PubMed

    Rahman, Shah Atiqur; Huang, Yuxiao; Claassen, Jan; Heintzman, Nathaniel; Kleinberg, Samantha

    2015-12-01

    Most clinical and biomedical data contain missing values. A patient's record may be split across multiple institutions, devices may fail, and sensors may not be worn at all times. While these missing values are often ignored, this can lead to bias and error when the data are mined. Further, the data are not simply missing at random. Instead the measurement of a variable such as blood glucose may depend on its prior values as well as that of other variables. These dependencies exist across time as well, but current methods have yet to incorporate these temporal relationships as well as multiple types of missingness. To address this, we propose an imputation method (FLk-NN) that incorporates time lagged correlations both within and across variables by combining two imputation methods, based on an extension to k-NN and the Fourier transform. This enables imputation of missing values even when all data at a time point is missing and when there are different types of missingness both within and across variables. In comparison to other approaches on three biological datasets (simulated and actual Type 1 diabetes datasets, and multi-modality neurological ICU monitoring) the proposed method has the highest imputation accuracy. This was true for up to half the data being missing and when consecutive missing values are a significant fraction of the overall time series length. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Early-onset neonatal sepsis is associated with a high heart rate during automatically selected stationary periods.

    PubMed

    Nguyen, Nga; Vandenbroucke, Laurent; Hernández, Alfredo; Pham, Tu; Beuchée, Alain; Pladys, Patrick

    2017-05-01

    This study examined the heart rate variability characteristics associated with early-onset neonatal sepsis in a prospective, observational controlled study. Eligible patients were full-term neonates hospitalised with clinical signs that suggested early-onset sepsis and a C-reactive protein of >10 mg/L. Sepsis was considered proven in cases of symptomatic septicaemia, meningitis, pneumonia or enterocolitis. Heart rate variability parameters (n = 16) were assessed from five-, 15- and 30-minute stationary sequences automatically selected from electrocardiographic recordings performed at admission and compared with a control group using the U-test with post hoc Benjamini-Yekutieli correction. Stationary sequences corresponded to the periods with the lowest changes of heart rate variability over time. A total of 40 full-term infants were enrolled, including 14 with proven sepsis. The mean duration of the cardiac cycle length was lower in the proven sepsis group than in the control group (n = 11), without other significant changes in heart rate variability parameters. These durations, measured in five-minute stationary periods, were 406 (367-433) ms in proven sepsis group versus 507 (463-522) ms in the control group (p < 0.05). Early-onset neonatal sepsis was associated with a high mean heart rate measured during automatically selected stationary periods. ©2017 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  4. Hazardous alcohol use and intimate partner violence in the military: understanding protective factors.

    PubMed

    Foran, Heather M; Heyman, Richard E; Smith Slep, Amy M; Snarr, Jeffery D

    2012-09-01

    Hazardous alcohol use is a well-established risk factor for men's intimate partner violence (IPV), with dozens of studies demonstrating the association. The current study extends understanding of the hazardous alcohol use-IPV link by examining what factors moderate this association in a more systematic and broader way that has been done in past studies. Individual, family, workplace, community, and developmental factors were tested as moderators of the hazardous alcohol use and IPV link in a large, representative sample of active duty service members (the 2006 Community Assessment), and the results were tested for replicability in a hold-out sample. Two family variables (relationship satisfaction and parent-child satisfaction), 1 community variable (community safety), and 3 developmental variables (years in the military, marital length, and family income/pay grade) cross-validated as significant moderators of the association between men's hazardous alcohol use and IPV. Across the significant moderators, the association between hazardous alcohol use and men's IPV was weakened by maturation/development, improved community safety, and better relationship functioning. No individual or workplace variables were significant moderators for men, and there were no significant moderators found for women. The results support the importance of a developmental and relational perspective to understanding the hazardous alcohol use-IPV link, rather than solely an individual coping perspective. PsycINFO Database Record (c) 2012 APA, all rights reserved.

  5. The effect of electronic health record implementation on community emergency department operational measures of performance.

    PubMed

    Ward, Michael J; Landman, Adam B; Case, Karen; Berthelot, Jessica; Pilgrim, Randy L; Pines, Jesse M

    2014-06-01

    We study the effect of an emergency department (ED) electronic health record implementation on the operational metrics of a diverse group of community EDs. We performed a retrospective before/after analysis of 23 EDs from a single management group that experienced ED electronic health record implementation (with the majority of electronic health records optimized specifically for ED use). We obtained electronic data for 4 length of stay measures (arrival to provider, admitted, discharged, and overall length of stay) and 4 measures of operational characteristics (left before treatment complete, significant returns, overall patient satisfaction, and provider efficiency). We compared the 6-month "baseline" period immediately before implementation with a "steady-state" period commencing 6 months after implementation for all 8 metrics. For the length of stay measures, there were no differences in the arrival-to-provider interval (difference of -0.02 hours; 95% confidence interval [CI] of difference -0.12 to 0.08), admitted length of stay (difference of 0.10 hours; 95% CI of difference -0.17 to 0.37), discharged length of stay (difference of 0.07 hours; 95% CI of difference -0.07 to 0.22), and overall length of stay (difference of 0.11 hours; 95% CI of difference -0.04 to 0.27). For operational characteristics, there were no differences in the percentage who left before treatment was complete (difference of 0.24%; 95% CI of difference -0.47% to 0.95%), significant returns (difference of -0.04%; 95% CI of difference -0.48% to 0.39%), overall percentile patient satisfaction (difference of -0.02%; 95% CI of difference -2.35% to 2.30%), and provider efficiency (difference of -0.05 patients/hour; 95% CI of difference -0.11 to 0.02). There is no meaningful difference in 8 measures of operational performance for community EDs experiencing optimized ED electronic health record implementation between a baseline and steady-state period. Copyright © 2014 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.

  6. Plant-wax D/H ratios in the southern European Alps record multiple aspects of climate variability

    NASA Astrophysics Data System (ADS)

    Wirth, Stefanie B.; Sessions, Alex L.

    2016-09-01

    We present a Younger Dryas-Holocene record of the hydrogen isotopic composition of sedimentary plant waxes (δDwax) from the southern European Alps (Lake Ghirla, N-Italy) to investigate its sensitivity to climatic forcing variations in this mid-latitude region (45°N). A modern altitudinal transect of δD values of river water and leaf waxes in the Lake Ghirla catchment is used to test present-day climate sensitivity of δDwax. While we find that altitudinal effects on δDwax are minor at our study site, temperature, precipitation amount, and evapotranspiration all appear to influence δDwax to varying extents. In the lake-sediment record, δDwax values vary between -134 and -180‰ over the past 13 kyr. The long-term Holocene pattern of δDwax parallels the trend of decreasing temperature and is thus likely forced by the decline of northern hemisphere summer insolation. Shorter-term fluctuations, in contrast, may reflect both temperature and moisture-source changes. During the cool Younger Dryas and Little Ice Age (LIA) periods we observe unexpectedly high δDwax values relative to those before and after. We suggest that a change towards a more D-enriched moisture source is required during these intervals. In fact, a shift from northern N-Atlantic to southern N-Atlantic/western Mediterranean Sea sources would be consistent with a southward migration of the Westerlies with climate cooling. Prominent δDwax fluctuations in the early and middle Holocene are negative and potentially associated with temperature declines. In the late Holocene (<4 kyr BP), excursions are partly positive (as for the LIA) suggesting a stronger influence of moisture-source changes on δDwax variation. In addition to isotopic fractionations of the hydrological cycle, changes in vegetation composition, in the length of the growing season, and in snowfall amount provide additional potential sources of variability, although we cannot yet quantitatively assess these in the paleo-record. We conclude that while our δDwax record from the Alps does contain climatic information, it is a complicated record that would require additional constraints to be robustly interpreted. This also has important implications for other water-isotope-based proxy records of precipitation and hydro-climate from this region, such as cave speleothems.

  7. Holocene Paleolimnological Records from Thule, Northwestern Greenland

    NASA Astrophysics Data System (ADS)

    Corbett, L.; Osterberg, E. C.; Kelly, M. A.; Axford, Y.

    2012-12-01

    Assessing Holocene climatic and environmental variability around the margin of the Greenland Ice Sheet provides important information against which to compare ice sheet margin fluctuations. Here, we report preliminary results from ongoing research in northwestern Greenland. We present records of physical properties of lake sediments and use these to make inferences about the evolution of the lake and its surroundings over the latter half of the Holocene. We collected two sediment cores, 90 and 72 cm in length, from a small (surface area ~0.3 km2), shallow (maximum depth ~4.5 m) lake at 76°33'40''N 68°26'31''W near Thule Air Base in July 2012. The length of the cores was limited by the length of the core barrel and does not reflect the total thickness of sediment in the lake. The lake is situated within the glacial limit and likely formed subsequent to deglaciation of the region during early Holocene time. No glaciers exist within the lake's catchment today; the primary modern source of sediment is a perennial inflow from the west. We developed a preliminary depth-age model using radiocarbon ages of terrestrial organic macrofossils. Thus far, we have analyzed the sediments for magnetic susceptibility and loss-on-ignition. A radiocarbon age of 6069 ± 90 cal yr BP at the base of the core indicates that the sediments preserve a continuous record of middle to late Holocene conditions. The top of both cores consists of a thick (~12 cm) layer of dark gray unlaminated sediments, while the rest of the material in both cores is lighter brown to olive, finely laminated sediment. The upper layer is characterized by low water content (<25%), low loss-on-ignition (<5%), and high magnetic susceptibility (~150-250 x10-6). Conversely, the laminated sediments beneath have higher water content (~40-50%), higher loss-on-ignition (~5-10%), and much lower magnetic susceptibility (<50 x10-6). We hypothesize that the upper, less organic unit may represent a single event in the lake's recent history. We are refining the depth-age model with more radiocarbon ages, measuring grain size and carbon to nitrogen ratios of the sediments, and evaluating possible linkages between the sediment physical properties and precipitation as recorded by annual accumulation in ice cores in northwestern Greenland and Arctic Canada. This project will provide a foundation for future work in Thule investigating Holocene fluctuations of local ice cap and ice sheet margin positions.

  8. Youth Baseball Pitching Stride Length: Normal Values and Correlation With Field Testing

    PubMed Central

    Fry, Karl E.; Pipkin, Andrew; Wittman, Kelcie; Hetzel, Scott; Sherry, Marc

    2016-01-01

    Background: Pitching biomechanical analysis has been recommended as an important component of performance, injury prevention, and rehabilitation. Normal values for youth pitching stride length have not been established, leading to application of normative values found among professional pitchers to youth pitchers. Hypotheses: The average youth pitching stride length will be significantly less than that of college and professional pitchers. There will be a positive correlation between stride length, lower extremity power, balance, and pitching experience. Study Design: Prospective cohort study. Level of Evidence: Level 3. Methods: Ninety-two youth baseball pitchers (aged 9-14 years) met the inclusion/exclusion criteria and completed the study. Stride length was recorded using a Dartfish video system over 3 maximal effort pitches. Both intra- and interrater reliability was calculated for the assessment of stride length. Double-leg vertical jump, single-leg stance time, leg length, weight, age, and pitching experience were also recorded. Results: Mean (SD) stride length was 66.0% (7.1%) of height. Stride length was correlated (P < 0.01) with vertical jump (0.38), pitching experience (0.36), and single-leg balance (0.28), with excellent intra- and interrater reliability (0.985 or higher). No significant correlations between stride length and body weight, leg length, or age existed. Conclusions: There was a significant difference between youth pitching stride length and the current published norms for older and more elite throwers. There was a positive correlation between stride length and lower extremity power, pitching experience, and single-leg balance. Clinical Relevance: Two-dimensional analysis of stride length allows for the assessment of pitching biomechanics in a practical manner. These values can be used for return to pitching parameters after an injury and designing injury prevention and performance programs. PMID:27864504

  9. Youth Baseball Pitching Stride Length: Normal Values and Correlation With Field Testing.

    PubMed

    Fry, Karl E; Pipkin, Andrew; Wittman, Kelcie; Hetzel, Scott; Sherry, Marc

    Pitching biomechanical analysis has been recommended as an important component of performance, injury prevention, and rehabilitation. Normal values for youth pitching stride length have not been established, leading to application of normative values found among professional pitchers to youth pitchers. The average youth pitching stride length will be significantly less than that of college and professional pitchers. There will be a positive correlation between stride length, lower extremity power, balance, and pitching experience. Prospective cohort study. Level 3. Ninety-two youth baseball pitchers (aged 9-14 years) met the inclusion/exclusion criteria and completed the study. Stride length was recorded using a Dartfish video system over 3 maximal effort pitches. Both intra- and interrater reliability was calculated for the assessment of stride length. Double-leg vertical jump, single-leg stance time, leg length, weight, age, and pitching experience were also recorded. Mean (SD) stride length was 66.0% (7.1%) of height. Stride length was correlated ( P < 0.01) with vertical jump (0.38), pitching experience (0.36), and single-leg balance (0.28), with excellent intra- and interrater reliability (0.985 or higher). No significant correlations between stride length and body weight, leg length, or age existed. There was a significant difference between youth pitching stride length and the current published norms for older and more elite throwers. There was a positive correlation between stride length and lower extremity power, pitching experience, and single-leg balance. Two-dimensional analysis of stride length allows for the assessment of pitching biomechanics in a practical manner. These values can be used for return to pitching parameters after an injury and designing injury prevention and performance programs.

  10. Emission response from extended length, variable geometry gas turbine combustor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Troth, D.L.; Verdouw, A.J.; Tomlinson, J.G.

    1974-01-01

    A program to analyze, select, and experimentally evaluate low emission combustors for aircraft gas turbine engines is conducted to demonstrate a final combustor concept having a 50 percent reduction in total mass emissions (carbon monoxide, unburnt hydrocarbons, oxides of nitrogen, and exhaust smoke) without an increase in any specific pollutant. Research conducted under an Army Contract established design concepts demonstrating significant reductions in CO and UHC emissions. Two of these concepts were an extended length intermediate zone to consume CO and UHC and variable geometry to control the primary zone fuel air ratio over varying power conditions. Emission reduction featuresmore » were identified by analytical methods employing both reaction kinetics and empirical correlations. Experimental results were obtained on a T63 component combustor rig operating at conditions simulating the engine over the complete power operating range with JP-4 fuel. A combustor incorporating both extended length and variable geometry was evaluated and the performance and emission results are reported. These results are compared on the basis of a helicopter duty cycle and the EPA 1979 turboprop regulation landing take off cycle. The 1979 EPA emission regulations for P2 class engines can be met with the extended length variable geometry combustor on the T63 turboprop engine.« less

  11. Early Detection of Heart Failure Using Electronic Health Records: Practical Implications for Time Before Diagnosis, Data Diversity, Data Quantity, and Data Density.

    PubMed

    Ng, Kenney; Steinhubl, Steven R; deFilippi, Christopher; Dey, Sanjoy; Stewart, Walter F

    2016-11-01

    Using electronic health records data to predict events and onset of diseases is increasingly common. Relatively little is known, although, about the tradeoffs between data requirements and model utility. We examined the performance of machine learning models trained to detect prediagnostic heart failure in primary care patients using longitudinal electronic health records data. Model performance was assessed in relation to data requirements defined by the prediction window length (time before clinical diagnosis), the observation window length (duration of observation before prediction window), the number of different data domains (data diversity), the number of patient records in the training data set (data quantity), and the density of patient encounters (data density). A total of 1684 incident heart failure cases and 13 525 sex, age-category, and clinic matched controls were used for modeling. Model performance improved as (1) the prediction window length decreases, especially when <2 years; (2) the observation window length increases but then levels off after 2 years; (3) the training data set size increases but then levels off after 4000 patients; (4) more diverse data types are used, but, in order, the combination of diagnosis, medication order, and hospitalization data was most important; and (5) data were confined to patients who had ≥10 phone or face-to-face encounters in 2 years. These empirical findings suggest possible guidelines for the minimum amount and type of data needed to train effective disease onset predictive models using longitudinal electronic health records data. © 2016 American Heart Association, Inc.

  12. Mesoscale Circulation Variability from Five years of Quasi-continuous Glider Observations and Numerical Simulation at a Key Sub-basin 'Choke' Point.

    NASA Astrophysics Data System (ADS)

    Heslop, E. E.; Mourre, B.; Juza, M.; Troupin, C.; Escudier, R.; Torner, M.; Tintore, J.

    2016-02-01

    Quasi-continuous glider observations over 5 years have uniquely characterised a high frequency variability in the circulation through the Ibiza Channel, an important `choke' point in the Western Mediterranean Sea. This `choke' point governs the basin/sub-basin scale circulation and the north/south exchanges of different water masses. The resulting multi-scale variability impacts the regional shelf and open ocean ecosystems, including the spawning grounds of Atlantic bluefin tuna. Through the unique glider record we show the relevance of the weekly/mesoscale variability, which is of same order as the previously established seasonal and inter-annual variability. To understand the drivers of this variability we combine the glider data with numerical simulations (WMOP) and altimetry. Two key drivers are identified; extreme winter events, which cause the formation of a cold winter mode water (Winter Intermediate Water) in the shelf areas to the north of the Ibiza Channel, and mesoscale activity, which to the north produce channel `blocking' eddies and to the south intermittent and vigorous flows of fresher `Atlantic' waters through the Ibiza Channel. Results from the 2 km resolution WMOP are compared with the high-resolution (2 - 3 km.) glider data, giving insight into model validation across different scales, for both circulation and water masses. There is an emerging consensus that gliders can uniquely access critical time and length scales and in this study gliders complement existing satellite measurements and models, while opening up new capabilities for multidisciplinary, autonomous and high-resolution ocean observation.

  13. Ocean angular momentum signals in a climate model and implications for Earth rotation

    NASA Astrophysics Data System (ADS)

    Ponte, R. M.; Rajamony, J.; Gregory, J. M.

    2002-03-01

    Estimates of ocean angular momentum (OAM) provide an integrated measure of variability in ocean circulation and mass fields and can be directly related to observed changes in Earth rotation. We use output from a climate model to calculate 240 years of 3-monthly OAM values (two equatorial terms L1 and L2, related to polar motion or wobble, and axial term L3, related to length of day variations) representing the period 1860-2100. Control and forced runs permit the study of the effects of natural and anthropogenically forced climate variability on OAM. All OAM components exhibit a clear annual cycle, with large decadal modulations in amplitude, and also longer period fluctuations, all associated with natural climate variability in the model. Anthropogenically induced signals, inferred from the differences between forced and control runs, include an upward trend in L3, related to inhomogeneous ocean warming and increases in the transport of the Antarctic Circumpolar Current, and a significantly weaker seasonal cycle in L2 in the second half of the record, related primarily to changes in seasonal bottom pressure variability in the Southern Ocean and North Pacific. Variability in mass fields is in general more important to OAM signals than changes in circulation at the seasonal and longer periods analyzed. Relation of OAM signals to changes in surface atmospheric forcing are discussed. The important role of the oceans as an excitation source for the annual, Chandler and Markowitz wobbles, is confirmed. Natural climate variability in OAM and related excitation is likely to measurably affect the Earth rotation, but anthropogenically induced effects are comparatively weak.

  14. Rapid grounding line migration induced by internal variability of a marine-terminating ice stream

    NASA Astrophysics Data System (ADS)

    Robel, A.; Schoof, C.; Tziperman, E.

    2013-12-01

    Numerous studies have found significant variability in the velocity of ice streams to be a prominent feature of geomorphologic records in the Siple Coast (Catania et al. 2012) and other regions in West Antarctica (Dowdeswell et al. 2008). Observations indicate that grounding line position is strongly influenced by ice stream variability, producing rapid grounding line migration in the recent past (Catania et al. 2006) and the modern (Joughin & Tulaczyk 2002). We analyze the interaction of grounding line mass flux and position in a marine-terminating ice stream using a stretch-coordinate flowline model. This model is based on that described in Schoof (2007), with a mesh refined near the grounding line to ensure accurate resolution of the mechanical transition zone. Here we have added lateral shear stress (Dupont & Alley 2005) and an undrained plastic bed (Tulaczyk et al. 2000). The parameter dependence of ice stream variability seen in this model compares favorably to both simpler (Robel et al. 2013) and more complex (van der Wel et al. 2013) models, though with some key differences. We find that thermally-induced internal ice stream variability can cause very rapid grounding line migration even in the absence of retrograde bed slopes or external forcing. Activation waves propagate along the ice stream length and trigger periods of rapid grounding line migration. We compare the behavior of the grounding line due to internal ice stream variability to changes triggered externally at the grounding line such as the rapid disintegration of buttressing ice shelves. Implications for Heinrich events and the Marine Ice Sheet Instability are discussed.

  15. Can aircraft noise less than or equal 115 to dBA adversely affect reproductive outcome in USAF women?

    NASA Astrophysics Data System (ADS)

    Brubaker, P. A.

    1985-06-01

    It has been suggested, mainly through animal studies, that exposure to high noise levels may be associated with lower birth weight, reduced gestational length and other adverse reproductive outcomes. Few studies have been done on humans to show this association. The Air Force employs pregnant women in areas where there is a high potential for exposure to high noise levels. This study proposes a method to determine if there is an association between high frequency noise levels or = 115 dBA and adverse reproductive outcomes through a review of records and self-administered questionnaires in a case-comparison design. Prevelance rates will be calculated and a multiple logistic regression analysis computed for the independent variables that can affect reproduction.

  16. Motor origins of tool use.

    PubMed

    Kahrs, Björn A; Jung, Wendy P; Lockman, Jeffrey J

    2013-01-01

    The current study examines the developmental trajectory of banging movements and its implications for tool use development. Twenty (6- to 15-month-old) infants wore reflective markers while banging a handled cube; movements were recorded at 240 Hz. Results indicated that through the second half-year, banging movements undergo developmental changes making them ideally suited for instrumental hammering and pounding. Younger infants were inefficient and variable when banging the object: Their hands followed circuitous paths of great lengths at high velocities. By 1 year, infants showed consistent and efficient straight up-down hand trajectories of smaller magnitude and velocity, allowing for precise aiming and delivering dependable levels of force. The findings suggest that tool use develops gradually from infants' existing manual behaviors. © 2012 The Authors. Child Development © 2012 Society for Research in Child Development, Inc.

  17. Estimation of stature from sternal lengths. A correlation meta-analysis.

    PubMed

    Yammine, Kaissar; Assi, Chahine

    2017-01-01

    Methods based on the positive linear relationship existing between stature and long bones are most commonly used to estimate living stature in forensic anthropology. The length of the sternum and its parts has been advanced as a plausible alternative to estimate stature when such long bones are missing or damaged. This meta-analysis aims to quantify evidence on the correlation between the sternum/sternal parts length and stature. Nine studies were included with 1118 sternal bones. Analyses showed that the length of the meso-sternum (manubrium + body) yielded the best correlation with stature; 53.5% and 55.42% for men and women, respectively. The second best variable is the total sternal length with correlations of 44.3% and 55% for men and women, respectively. Subgroup analysis of autopsy studies demonstrated even a higher correlation of 58.2% for the meso-sternal length. Manubrium and body lengths showed the least correlation values. Except for the body length, females exhibit a better correlation than man between all other sternal lengths and stature. While the meso-sternal length is found to be the most correlated variable with stature, all sternal lengths are to be considered with caution when estimating stature. The relatively low values of the weighted correlation results should raise the question of reliability and limit the use of sternal length when long bones are available. Future research using larger samples from different populations and taking into account the fusion status of the sternum are needed.

  18. Abrupt Shift in the Observed Runoff from the Southwest Greenland Ice Sheet?

    NASA Astrophysics Data System (ADS)

    Ahlstrom, A.; Petersen, D.; Box, J.; Langen, P. P.; Citterio, M.

    2016-12-01

    Mass loss of the Greenland ice sheet has contributed significantly to sea level rise in recent years and is considered a crucial parameter when estimating the impact of future climate change. Few observational records of sufficient length exist to validate surface mass balance models, especially the estimated runoff. Here we present an observation time series from 1975-2014 of discharge from a large proglacial lake, Tasersiaq, in West Greenland (66.3°N, 50.4°W) with a mainly ice-covered catchment. We argue that the discharge time series is representative measure of ice sheet runoff, making it the only observational record of runoff to exceed the 30-year period needed to assess the climatological state of the ice sheet. We proceed to isolate the runoff part of the signal from precipitation and identified glacial lake outburst floods from a small sub-catchment. Similarly, the impact from major volcanic eruptions is clearly identified. We examine the trend and annual variability in the annual discharge, relating it to likely atmospheric forcing mechanisms and compare the observational time series with modelled runoff from the regional climate model HIRHAM.

  19. Using the landmark method for creating prediction models in large datasets derived from electronic health records.

    PubMed

    Wells, Brian J; Chagin, Kevin M; Li, Liang; Hu, Bo; Yu, Changhong; Kattan, Michael W

    2015-03-01

    With the integration of electronic health records (EHRs), health data has become easily accessible and abounded. The EHR has the potential to provide important healthcare information to researchers by creating study cohorts. However, accessing this information comes with three major issues: 1) Predictor variables often change over time, 2) Patients have various lengths of follow up within the EHR, and 3) the size of the EHR data can be computationally challenging. Landmark analyses provide a perfect complement to EHR data and help to alleviate these three issues. We present two examples that utilize patient birthdays as landmark times for creating dynamic datasets for predicting clinical outcomes. The use of landmark times help to solve these three issues by incorporating information that changes over time, by creating unbiased reference points that are not related to a patient's exposure within the EHR, and reducing the size of a dataset compared to true time-varying analysis. These techniques are shown using two example cohort studies from the Cleveland Clinic that utilized 4.5 million and 17,787 unique patients, respectively.

  20. Three Echiniscidae species (Tardigrada: Heterotardigrada) new to the Polish fauna, with the description of a new gonochoristic Bryodelphax Thulin, 1928.

    PubMed

    GĄsiorek, Piotr; Degma, Peter

    2018-04-16

    During a faunistic survey in the Pieniny and Tatra Mountains three species of Echiniscidae new to Poland, including one new to science, were found. Bryodelphax instabilis sp. nov. is characterised by an instable number of ventral plates, deep faceting of the scapular plate, having dorsal plates covered either with pseudopores or pores, and striking sexual dimorphism. Two first records, namely Echiniscus militaris and E. spiniger, are rare taxa of upland-mountain character, which have already been reported from a few European countries since the original description at the beginning of the XXth century. The interspecific appendage length variability and development of pedal plates in the spinulosus group, to which E. spiniger belongs, and their taxonomic importance is discussed. Notes relating to sexual dimorphism within the newly recorded Pseudechiniscus facettalis, are also presented. Echiniscus testudo is reported from the Polish part of the Tatra Mountains for the first time. Succeeding findings confirm the high tardigrade α-diversity in the Polish mountain ranges. An amended key for Polish Heterotardigrada is provided.

  1. External morphology and calling song characteristics in Tibicen plebejus (Hemiptera: Cicadidae).

    PubMed

    Mehdipour, Maedeh; Sendi, Jalal Jalali; Zamanian, Hossein

    2015-02-01

    Tibicen plebejus is the largest cicada native to the ecosystem in northern Iran. The male cicada produces a loud calling song for attracting females from a long distance. It is presumed that the female selects a mate based on a combination of passive and active mechanisms, but it is not known if she selects for size, nor if the male's size correlates with any characteristic of the advertisement call. In this study, we report the relationship between calling song features and morphological characters in the male of T. plebejus. Research was conducted in northern Iran during the summer of 2010. Seventeen males were collected and their calling songs were recorded in a natural environment. Two morphological characters were measured: length and weight. Maximum, minimum and average of values of 10 key acoustic variables of the calling song were analyzed: phrase duration, phrase part 1, phrase part 2, number of phrases per minute, echeme duration, echeme period, interecheme interval, number of echeme per second, echeme/intereheme ratio, and dominant frequency. The data were tested for the level of association between morphology and acoustic variables using simple linear regression. In conclusion, in terms of song structure, three significant positive correlations existed between length and (1) mean echeme duration, (2) mean echeme/interecheme ratio, (3) maximum echeme/interecheme ratio. We found out also four significant negative correlations between both length and weight with (1) minimum interecheme intervals, (2) mean dominant frequency, (3) minimum dominant frequency, (4) maximum dominant frequency, and between weight and (1) minimum interecheme intervals, (2) mean dominant frequency, (3) minimum dominant frequency, (4) maximum dominant frequency. It can be found that larger males of T. plebejus produce songs of lower frequency and are less silent between echemes. Copyright © 2014 Académie des sciences. Published by Elsevier SAS. All rights reserved.

  2. Butterfly Sprint Swimming Technique, Analysis of Somatic and Spatial-Temporal Coordination Variables

    PubMed Central

    Stanula, Arkadiusz; Krężałek, Piotr; Ostrowski, Andrzej; Kaca, Marcin; Głąb, Grzegorz

    2017-01-01

    Abstract The aim of this study was to investigate somatic properties and force production of leg extensor muscles measured in the countermovement jump test (CMJ), as well as to analyse kinematic variables of sprint surface butterfly swimming. Thirty-four male competitive swimmers were recruited with an average age of 19.3 ± 1.83 years. Their average body height (BH) was 183.7 ± 5.93 cm, body fat content 10.8 ± 2.64% and body mass (BM) 78.3 ± 5.0 kg. Length measurements of particular body segments were taken and a counter movement jump (CMJ) as well as an all-out 50 m butterfly speed test were completed. The underwater movements of the swimmers’ bodies were recorded with a digital camera providing side-shots. We registered a significant relationship between body mass (r = 0.46), lean body mass (r = 0.48) and sprint surface butterfly swimming (VSBF). The anaerobic power measured in the CMJ test, total body length (TBL) as well as upper and lower extremity length indices did not influence swimming speed significantly. The temporal entry-kick index (the time ratio between the first kick and arm entry) significantly influenced VSBF (r = -0.45). Similarly, medium power of the coefficient was indicated between a) stroke rate kinematics (SR), b) duration of the first leg kick (LP1), c) air phase duration of arm recovery (Fly-arm), and VSBF (r = 0.40; r = 0.40 and r = 0.41, respectively). The entry-kick temporal index showed that, in the butterfly cycle, an appropriately early executed initial kick when compared to arm entry was associated with a longer arm propulsion phase, which in turn was associated with minimizing resistive gliding phases and enabled relatively longer and less resistive air arm recovery (higher value of the fly-arm index). The higher value of SR kinematic was another important element of the best butterfly results in this study. PMID:29339985

  3. An integrated system for multichannel neuronal recording with spike/LFP separation, integrated A/D conversion and threshold detection.

    PubMed

    Perelman, Yevgeny; Ginosar, Ran

    2007-01-01

    A mixed-signal front-end processor for multichannel neuronal recording is described. It receives 12 differential-input channels of implanted recording electrodes. A programmable cutoff High Pass Filter (HPF) blocks dc and low-frequency input drift at about 1 Hz. The signals are band-split at about 200 Hz to low-frequency Local Field Potential (LFP) and high-frequency spike data (SPK), which is band limited by a programmable-cutoff LPF, in a range of 8-13 kHz. Amplifier offsets are compensated by 5-bit calibration digital-to-analog converters (DACs). The SPK and LFP channels provide variable amplification rates of up to 5000 and 500, respectively. The analog signals are converted into 10-bit digital form, and streamed out over a serial digital bus at up to 8 Mbps. A threshold filter suppresses inactive portions of the signal and emits only spike segments of programmable length. A prototype has been fabricated on a 0.35-microm CMOS process and tested successfully, demonstrating a 3-microV noise level. Special interface system incorporating an embedded CPU core in a programmable logic device accompanied by real-time software has been developed to allow connectivity to a computer host.

  4. Climate variability at the onset of the Younger Dryas as reflected in annually resolved tree-ring stable isotope chronologies

    NASA Astrophysics Data System (ADS)

    Pieper, H.; Helle, G.; Brauer, A.; Kaiser, K. F.; Miramont, C.

    2013-12-01

    The Younger Dryas interval during the Last Glacial Termination was an abrupt return to glacial-like conditions punctuating the transition to a warmer, interglacial climate. Despite recent advances in the layer counting of ice-core records of the termination, the timing and length of the Younger Dryas remain controversial. Late Glacial and early Holocene tree-ring chronologies are rare, however, they contain valuable information about past environmental conditions at annual time resolution. Changes in tree-ring growth rates can be related to past climate anomalies and changes in the carbon and oxygen isotope composition of tree-ring cellulose reflect atmospheric and hydrospheric changes. We are investigating a 860-year (13200 - 12340 cal BP) dated dendrochronological record of Late Glacial and Early Holocene chronologies of scots pine (Pinus sylvestris L.) from subfossil tree remnants from Barbiers River (Moyenne Durance, Southern French Alps), as well as from Swiss (Dättnau, Landikon and Gänziloh) sites. Dendro-ecological parameters, such as ring width and stable isotope variations (δ 13C und δ 18O) are used to infer past environmental conditions. We will present our first carbon and oxygen isotope records from tree rings reflecting the environmental changes at the Alleröd/Younger Dryas -transition.

  5. Morphological analysis of the Chinese Cipangopaludina species (Gastropoda; Caenogastropoda: Viviparidae).

    PubMed

    Lu, Hong-Fa; Du, Li-Na; Li, Zhi-Qiang; Chen, Xiao-Yong; Yang, Jun-Xing

    2014-11-18

    Viviparidae are widely distributed around the globe, but there are considerable gaps in the taxonomic record. To date, 18 species of the viviparid genus Cipangopaludina have been recorded in China, but there is substantial disagreement on the validity of this taxonomy. In this study, we described the shell and internal traits of these species to better discuss the validity of related species. We found that C. ampulliformis is synonym of C. lecythis, and C. wingatei is synonym of C. chinensis,while C. ampullacea and C. fluminalis are subspecies of C. lecythis and C. chinensis, respectively. C. dianchiensis should be paled in the genus Margarya, while C. menglaensis and C. yunnanensisbelong to genus Mekongia. Totally, this leaves 11 species and 2 subspecies recorded in China. Based on whether these specimens' spiral whorl depth was longer than aperture depth, these species or subspecies can be further divided into two groups, viz. chinensis group and cathayensis group, which can be determined from one another via the ratio of spiral depth and aperture depth, vas deferens and number of secondary branches of vas deferens. Additionally, Principal Component Analysis indicated that body whorl depth, shell width, aperture width and aperture length were main variables during species of Cipangopaludina. A key to all valid Chinese Cipangopaludina specieswere given.

  6. Morphological analysis of the Chinese Cipangopaludina species (Gastropoda; Caenogastropoda: Viviparidae)

    PubMed Central

    LU, Hong-Fa; DU, Li-Na; LI, Zhi-Qiang; CHEN, Xiao-Yong; YANG, Jun-Xing

    2014-01-01

    Viviparidae are widely distributed around the globe, but there are considerable gaps in the taxonomic record. To date, 18 species of the viviparid genus Cipangopaludina have been recorded in China, but there is substantial disagreement on the validity of this taxonomy. In this study, we described the shell and internal traits of these species to better discuss the validity of related species. We found that C. ampulliformis is synonym of C. lecythis, and C. wingatei is synonym of C. chinensis, while C. ampullacea and C. fluminalis are subspecies of C. lecythis and C. chinensis, respectively. C. dianchiensis should be paled in the genus Margarya, while C. menglaensis and C. yunnanensis belong to genus Mekongia. Totally, this leaves 11 species and 2 subspecies recorded in China. Based on whether these specimens’ spiral whorl depth was longer than aperture depth, these species or subspecies can be further divided into two groups, viz. chinensis group and cathayensis group, which can be determined from one another via the ratio of spiral depth and aperture depth, vas deferens and number of secondary branches of vas deferens. Additionally, Principal Component Analysis indicated that body whorl depth, shell width, aperture width and aperture length were main variables during species of Cipangopaludina. A key to all valid Chinese Cipangopaludina species were given. PMID:25465086

  7. The expression of the skeletal muscle force-length relationship in vivo: a simulation study.

    PubMed

    Winter, Samantha L; Challis, John H

    2010-02-21

    The force-length relationship is one of the most important mechanical characteristics of skeletal muscle in humans and animals. For a physiologically realistic joint range of motion and therefore range of muscle fibre lengths only part of the force-length curve may be used in vivo, i.e. only a section of the force-length curve is expressed. A generalised model of a mono-articular muscle-tendon complex was used to examine the effect of various muscle architecture parameters on the expressed section of the force-length relationship for a 90 degrees joint range of motion. The parameters investigated were: the ratio of tendon resting length to muscle fibre optimum length (L(TR):L(F.OPT)) (varied from 0.5 to 11.5), the ratio of muscle fibre optimum length to average moment arm (L(F.OPT):r) (varied from 0.5 to 5), the normalised tendon strain at maximum isometric force (c) (varied from 0 to 0.08), the muscle fibre pennation angle (theta) (varied from 0 degrees to 45 degrees) and the joint angle at which the optimum muscle fibre length occurred (phi). The range of values chosen for each parameter was based on values reported in the literature for five human mono-articular muscles with different functional roles. The ratios L(TR):L(F.OPT) and L(F.OPT):r were important in determining the amount of variability in the expressed section of the force-length relationship. The modelled muscle operated over only one limb at intermediate values of these two ratios (L(TR):L(F.OPT)=5; L(F.OPT):r=3), whether this was the ascending or descending limb was determined by the precise values of the other parameters. It was concluded that inter-individual variability in the expressed section of the force-length relationship is possible, particularly for muscles with intermediate values of L(TR):L(F.OPT) and L(F.OPT):r such as the brachialis and vastus lateralis. Understanding the potential for inter-individual variability in the expressed section is important when using muscle models to simulate movement. (c) 2009 Elsevier Ltd. All rights reserved.

  8. Modeling Menstrual Cycle Length and Variability at the Approach of Menopause Using Hierarchical Change Point Models

    PubMed Central

    Huang, Xiaobi; Elliott, Michael R.; Harlow, Siobán D.

    2013-01-01

    SUMMARY As women approach menopause, the patterns of their menstrual cycle lengths change. To study these changes, we need to jointly model both the mean and variability of cycle length. Our proposed model incorporates separate mean and variance change points for each woman and a hierarchical model to link them together, along with regression components to include predictors of menopausal onset such as age at menarche and parity. Additional complexity arises from the fact that the calendar data have substantial missingness due to hormone use, surgery, and failure to report. We integrate multiple imputation and time-to event modeling in a Bayesian estimation framework to deal with different forms of the missingness. Posterior predictive model checks are applied to evaluate the model fit. Our method successfully models patterns of women’s menstrual cycle trajectories throughout their late reproductive life and identifies change points for mean and variability of segment length, providing insight into the menopausal process. More generally, our model points the way toward increasing use of joint mean-variance models to predict health outcomes and better understand disease processes. PMID:24729638

  9. Effects of a Flexibility and Relaxation Programme, Walking, and Nordic Walking on Parkinson's Disease

    PubMed Central

    Reuter, I.; Mehnert, S.; Leone, P.; Kaps, M.; Oechsner, M.; Engelhardt, M.

    2011-01-01

    Symptoms of Parkinson's disease (PD) progress despite optimized medical treatment. The present study investigated the effects of a flexibility and relaxation programme, walking, and Nordic walking (NW) on walking speed, stride length, stride length variability, Parkinson-specific disability (UPDRS), and health-related quality of life (PDQ 39). 90 PD patients were randomly allocated to the 3 treatment groups. Patients participated in a 6-month study with 3 exercise sessions per week, each lasting 70 min. Assessment after completion of the training showed that pain was reduced in all groups, and balance and health-related quality of life were improved. Furthermore, walking, and Nordic walking improved stride length, gait variability, maximal walking speed, exercise capacity at submaximal level, and PD disease-specific disability on the UPDRS in addition. Nordic walking was superior to the flexibility and relaxation programme and walking in improving postural stability, stride length, gait pattern and gait variability. No significant injuries occurred during the training. All patients of the Nordic walking group continued Nordic walking after completing the study. PMID:21603199

  10. The relationship between allometry and preferred transition speed in human locomotion.

    PubMed

    Ranisavljev, Igor; Ilic, Vladimir; Soldatovic, Ivan; Stefanovic, Djordje

    2014-04-01

    The purpose of this study was to explore the relationships between preferred transition speed (PTS) and anthropometric characteristics, body composition and different human body proportions in males. In a sample of 59 male students, we collected anthropometric and body composition data and determined individual PTS using increment protocol. The relationships between PTS and other variables were determined using Pearson correlation, stepwise linear and hierarchical regression. Body ratios were formed as quotient of two variables whereby at least one significantly correlated to PTS. Circular and transversal (except bitrochanteric diameter) body dimensions did not correlate with PTS. Moderate correlations were found between longitudinal leg dimensions (foot, leg and thigh length) and PTS, while the highest correlation was found for lower leg length (r=.488, p<.01). Two parameters related to body composition showed weak correlation with PTS: body fat mass (r=-.250, p<.05) and amount of lean leg mass scaled to body weight (r=.309, p<.05). Segmental body proportions correlated more significantly with PTS, where thigh/lower leg length ratio showed the highest correlation (r=.521, p<.01). Prediction model with individual variables (lower leg and foot length) have explained just 31% of PTS variability, while model with body proportions showed almost 20% better prediction (R(2)=.504). These results suggests that longitudinal leg dimensions have moderate influence on PTS and that segmental body proportions significantly more explain PTS than single anthropometric variables. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Using variable homography to measure emergent fibers on textile fabrics

    NASA Astrophysics Data System (ADS)

    Xu, Jun; Cudel, Christophe; Kohler, Sophie; Fontaine, Stéphane; Haeberlé, Olivier; Klotz, Marie-Louise

    2011-07-01

    A fabric's smoothness is a key factor to determine the quality of textile finished products and has great influence on the functionality of industrial textiles and high-end textile products. With popularization of the 'zero defect' industrial concept, identifying and measuring defective material in the early stage of production is of great interest for the industry. In the current market, many systems are able to achieve automatic monitoring and control of fabric, paper, and nonwoven material during the entire production process, however online measurement of hairiness is still an open topic and highly desirable for industrial applications. In this paper we propose a computer vision approach, based on variable homography, which can be used to measure the emergent fiber's length on textile fabrics. The main challenges addressed in this paper are the application of variable homography to textile monitoring and measurement, as well as the accuracy of the estimated calculation. We propose that a fibrous structure can be considered as a two-layer structure and then show how variable homography can estimate the length of the fiber defects. Simulations are carried out to show the effectiveness of this method to measure the emergent fiber's length. The true lengths of selected fibers are measured precisely using a digital optical microscope, and then the same fibers are tested by our method. Our experimental results suggest that smoothness monitored by variable homography is an accurate and robust method for quality control of important industrially fabrics.

  12. Influence of rice straw cooking conditions in the soda-ethanol-water pulping on the mechanical properties of produced paper sheets.

    PubMed

    Navaee-Ardeh, S; Mohammadi-Rovshandeh, J; Pourjoozi, M

    2004-03-01

    A normalized design was used to examine the influence of independent variables (alcohol concentration, cooking time and temperature) in the catalytic soda-ethanol pulping of rice straw on various mechanical properties (breaking length, burst, tear index and folding endurance) of paper sheets obtained from each pulping process. An equation of each dependent variable as a function of cooking variables (independent variables) was obtained by multiple non-linear regression using the least square method by MATLAB software for developing of empirical models. The ranges of alcohol concentration, cooking time and temperature were 40-65% (w/w), 150-180 min and 195-210 degrees C, respectively. Three-dimensional graphs of dependent variables were also plotted versus independent variables. The optimum values of breaking length, burst and tear index and folding endurance were 4683.7 (m), 30.99 (kN/g), 376.93 (mN m2/g) and 27.31, respectively. However, short cooking time (150 min), high ethanol concentration (65%) and high temperature (210 degrees C) could be used to produce papers with suitable burst and tear index. However, for papers with best breaking length and folding endurance low temperature (195 degrees C) was desirable. Differences between optimum values of dependent variables obtained by normalized design and experimental data were less than 20%.

  13. High-efficiency Gaussian key reconciliation in continuous variable quantum key distribution

    NASA Astrophysics Data System (ADS)

    Bai, ZengLiang; Wang, XuYang; Yang, ShenShen; Li, YongMin

    2016-01-01

    Efficient reconciliation is a crucial step in continuous variable quantum key distribution. The progressive-edge-growth (PEG) algorithm is an efficient method to construct relatively short block length low-density parity-check (LDPC) codes. The qua-sicyclic construction method can extend short block length codes and further eliminate the shortest cycle. In this paper, by combining the PEG algorithm and qua-si-cyclic construction method, we design long block length irregular LDPC codes with high error-correcting capacity. Based on these LDPC codes, we achieve high-efficiency Gaussian key reconciliation with slice recon-ciliation based on multilevel coding/multistage decoding with an efficiency of 93.7%.

  14. Forecasting Glacier Evolution and Hindcasting Paleoclimates In Light of Mass Balance Nonlinearities

    NASA Astrophysics Data System (ADS)

    Malone, A.; Doughty, A. M.; MacAyeal, D. R.

    2016-12-01

    Glaciers are commonly used barometers of present and past climate change, with their variations often being linked to shifts in the mean climate. Climate variability within a unchanging mean state, however, can produce short term mass balance and glacier length anomalies, complicating this linkage. Also, the mass balance response to this variability can be nonlinear, possibly impacting the longer term state of the glacier. We propose a conceptual model to understand these nonlinearities and quantify their impacts on the longer term mass balance and glacier length. The relationship between mass balance and elevation, i.e. the vertical balance profile (VBP), illuminates these nonlinearities (Figure A). The VBP, given here for a wet tropical glacier, is piecewise, which can lead to different mass balance responses to climate anomalies of similar magnitude but opposite sign. We simulate the mass balance response to climate variability by vertically (temperature anomalies) and horizontally (precipitation anomalies) transposing the VBP for the mean climate (Figure A). The resulting anomalous VBP is the superposition of the two translations. We drive a 1-D flowline model with 10,000 years of anomalous VBPs. The aggregate VBP for the mean climate including variability differs from the VBP for the mean climate excluding variability, having a higher equilibrium line altitude (ELA) and a negative mass balance (Figure B). Accordingly, the glacier retreats, and the equilibrium glacier length for the aggregate VBP is the same as the mean length from the 10,000 year flowline simulation (Figure C). The magnitude of the VBP shift and glacier retreat increases with greater temperature variability and larger discontinuities in the VBP slope. These results highlight the importance of both the climate mean and variability in determining the longer term state of the glacier. Thus, forecasting glacier evolution or hindcasting past climates should also include representation of climate variability.

  15. CRIB; the mineral resources data bank of the U.S. Geological Survey

    USGS Publications Warehouse

    Calkins, James Alfred; Kays, Olaf; Keefer, Eleanor K.

    1973-01-01

    The recently established Computerized Resources Information Bank (CRIB) of the U.S. Geological Survey is expected to play an increasingly important role in the study of United States' mineral resources. CRIB provides a rapid means for organizing and summarizing information on mineral resources and for displaying the results. CRIB consists of a set of variable-length records containing the basic information needed to characterize one or more mineral commodities, a mineral deposit, or several related deposits. The information consists of text, numeric data, and codes. Some topics covered are: name, location, commodity information, geology, production, reserves, potential resources, and references. The data are processed by the GIPSY program, which performs all the processing tasks needed to build, operate, and maintain the CRIB file. The sophisticated retrieval program allows the user to make highly selective searches of the files for words, parts of words, phrases, numeric data, word ranges, numeric ranges, and others, and to interrelate variables by logic statements to any degree of refinement desired. Three print options are available, or the retrieved data can be passed to another program for further processing.

  16. GrammarViz 3.0: Interactive Discovery of Variable-Length Time Series Patterns

    DOE PAGES

    Senin, Pavel; Lin, Jessica; Wang, Xing; ...

    2018-02-23

    The problems of recurrent and anomalous pattern discovery in time series, e.g., motifs and discords, respectively, have received a lot of attention from researchers in the past decade. However, since the pattern search space is usually intractable, most existing detection algorithms require that the patterns have discriminative characteristics and have its length known in advance and provided as input, which is an unreasonable requirement for many real-world problems. In addition, patterns of similar structure, but of different lengths may co-exist in a time series. In order to address these issues, we have developed algorithms for variable-length time series pattern discoverymore » that are based on symbolic discretization and grammar inference—two techniques whose combination enables the structured reduction of the search space and discovery of the candidate patterns in linear time. In this work, we present GrammarViz 3.0—a software package that provides implementations of proposed algorithms and graphical user interface for interactive variable-length time series pattern discovery. The current version of the software provides an alternative grammar inference algorithm that improves the time series motif discovery workflow, and introduces an experimental procedure for automated discretization parameter selection that builds upon the minimum cardinality maximum cover principle and aids the time series recurrent and anomalous pattern discovery.« less

  17. GrammarViz 3.0: Interactive Discovery of Variable-Length Time Series Patterns

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Senin, Pavel; Lin, Jessica; Wang, Xing

    The problems of recurrent and anomalous pattern discovery in time series, e.g., motifs and discords, respectively, have received a lot of attention from researchers in the past decade. However, since the pattern search space is usually intractable, most existing detection algorithms require that the patterns have discriminative characteristics and have its length known in advance and provided as input, which is an unreasonable requirement for many real-world problems. In addition, patterns of similar structure, but of different lengths may co-exist in a time series. In order to address these issues, we have developed algorithms for variable-length time series pattern discoverymore » that are based on symbolic discretization and grammar inference—two techniques whose combination enables the structured reduction of the search space and discovery of the candidate patterns in linear time. In this work, we present GrammarViz 3.0—a software package that provides implementations of proposed algorithms and graphical user interface for interactive variable-length time series pattern discovery. The current version of the software provides an alternative grammar inference algorithm that improves the time series motif discovery workflow, and introduces an experimental procedure for automated discretization parameter selection that builds upon the minimum cardinality maximum cover principle and aids the time series recurrent and anomalous pattern discovery.« less

  18. Development and pilot implementation of a locally developed Trauma Registry: lessons learnt in a low-income country.

    PubMed

    Mehmood, Amber; Razzak, Junaid Abdul; Kabir, Sarah; Mackenzie, Ellen J; Hyder, Adnan A

    2013-03-21

    Trauma registries (TRs) play an integral role in the assessment of trauma care quality. TRs are still uncommon in developing countries owing to awareness and cost. We present a case study of development and pilot implementation of "Karachi Trauma Registry" (KITR), using existing medical records at a tertiary-care hospital of Karachi, Pakistan to present results of initial data and describe its process of implementation. KITR is a locally developed, customized, electronic trauma registry based on open source software designed by local software developers in Karachi. Data for KITR was collected from November 2010 to January 2011. All patients presenting to the Emergency Department (ED) of the Aga Khan University Hospital (AKUH) with a diagnosis of injury as defined in ICD-9 CM were included. There was no direct contact with patients or health care providers for data collection. Basic demographics, injury details, event detail, injury severity and outcome were recorded. Data was entered in the KITR and reports were generated. Complete data of 542 patients were entered and analysed. The mean age of patients was 27 years, and 72.5% were males. About 87% of patients had sustained blunt injury. Falls and motor vehicle crashes were the most common mechanisms of injury. Head and face, followed by the extremities, were the most frequently injured anatomical regions. The mean Injury Severity Score (ISS) was 4.99 and there were 8 deaths. The most common missing variables in the medical records were ethnicity, ED notification prior to transfer, and pre-hospital IV fluids. Average time to review each chart was 14.5 minutes and entry into the electronic registry required 15 minutes. Using existing medical records, we were able to enter data on most variables including mechanism of injuries, burden of severe injuries and quality indicators such as length of stay in ED, injury to arrival delay, as well as generate injury severity and survival probability but missed information such as ethnicity, ED notification. To make the data collection process more effective, we propose provider based data collection or making a standardized data collection tool a part of medical records.

  19. Intraoperative non-record-keeping usage of anesthesia information management system workstations and associated hemodynamic variability and aberrancies.

    PubMed

    Wax, David B; Lin, Hung-Mo; Reich, David L

    2012-12-01

    Anesthesia information management system workstations in the anesthesia workspace that allow usage of non-record-keeping applications could lead to distraction from patient care. We evaluated whether non-record-keeping usage of the computer workstation was associated with hemodynamic variability and aberrancies. Auditing data were collected on eight anesthesia information management system workstations and linked to their corresponding electronic anesthesia records to identify which application was active at any given time during the case. For each case, the periods spent using the anesthesia information management system record-keeping module were separated from those spent using non-record-keeping applications. The variability of heart rate and blood pressure were also calculated, as were the incidence of hypotension, hypertension, and tachycardia. Analysis was performed to identify whether non-record-keeping activity was a significant predictor of these hemodynamic outcomes. Data were analyzed for 1,061 cases performed by 171 clinicians. Median (interquartile range) non-record-keeping activity time was 14 (1, 38) min, representing 16 (3, 33)% of a median 80 (39, 143) min of procedure time. Variables associated with greater non-record-keeping activity included attending anesthesiologists working unassisted, longer case duration, lower American Society of Anesthesiologists status, and general anesthesia. Overall, there was no independent association between non-record-keeping workstation use and hemodynamic variability or aberrancies during anesthesia either between cases or within cases. Anesthesia providers spent sizable portions of case time performing non-record-keeping applications on anesthesia information management system workstations. This use, however, was not independently associated with greater hemodynamic variability or aberrancies in patients during maintenance of general anesthesia for predominantly general surgical and gynecologic procedures.

  20. Megadroughts in Southwestern North America in ECHO-G Millennial Simulations and Their Comparison to Proxy Drought Reconstructions

    NASA Technical Reports Server (NTRS)

    Coats, Sloan; Smerdon, Jason E.; Seager, Richard; Cook, Benjamin I.; Gozalez-Rouco, J. F.

    2013-01-01

    Simulated hydroclimate variability in millennium-length forced transient and control simulations from the ECHAM and the global Hamburg Ocean Primitive Equation (ECHO-G) coupled atmosphere-ocean general circulation model (AOGCM) is analyzed and compared to 1000 years of reconstructed Palmer drought severity index (PDSI) variability from the North American Drought Atlas (NADA). The ability of the model to simulate megadroughts in the North American southwest is evaluated. (NASW: 25deg42.5degN, 125deg-105degW). Megadroughts in the ECHO-G AOGCM are found to be similar in duration and magnitude to those estimated from the NADA. The droughts in the forced simulation are not, however, temporally synchronous with those in the paleoclimate record, nor are there significant differences between the drought features simulated in the forced and control runs. These results indicate that model-simulated megadroughts can result from internal variability of the modeled climate system rather than as a response to changes in exogenous forcings. Although the ECHO-G AOGCM is capable of simulating megadroughts through persistent La Nina-like conditions in the tropical Pacific, other mechanisms can produce similarly extreme NASW moisture anomalies in the model. In particular, the lack of low-frequency coherence between NASW soil moisture and simulated modes of climate variability like the El Nino-Southern Oscillation, Pacific decadal oscillation, and Atlantic multidecadal oscillation during identified drought periods suggests that stochastic atmospheric variability can contribute significantly to the occurrence of simulated megadroughts in the NASW. These findings indicate that either an expanded paradigm is needed to understand multidecadal hydroclimate variability in the NASW or AOGCMs may incorrectly simulate the strength and/or dynamics of the connection between NASW hydroclimate variability and the tropical Pacific.

  1. Dynamic aspects of prescription drug use in an elderly population.

    PubMed Central

    Stuart, B; Coulson, N E

    1993-01-01

    OBJECTIVE. This study explores longitudinal patterns in outpatient prescription drug use in an elderly population. DATA SOURCES/STUDY SETTING. Enrollment records and prescription drug claims were obtained for a sample of elderly Pennsylvanians (N = 27,301) who had enrolled in the Pharmaceutical Assistance Contract for the Elderly (PACE) program at any time between July 1984 and June 1987. Study Design. The study tracks monthly prescription fill rates for sampled PACE beneficiaries from their initial enrollment month through disenrollment, death, or the end of the study (whichever occurred first). We specify two-part multivariate models to assess the effect of calendar time, length of time in the PACE program, and progression to disenrollment or death both on the probability of any prescription use and on the level of use among those who filled at least one prescription claim per month. Control variables include age, gender, race, income, residence, and marital status. DATA COLLECTION/EXTRACTION METHODS. Data were extracted from administrative files maintained by the PACE program, checked for errors, and then formatted as person-month records. PRINCIPAL FINDINGS/CONCLUSIONS. We find a strong positive relationship between drug use and the length of time persons are PACE-enrolled. Persons whose death occurs within a year have much higher prescription utilization rates than do persons whose death is at least a year away, and the differential increases as death nears. Persons who fail to renew PACE coverage use significantly fewer prescription drugs in the year prior to disenrollment. Holding age and other factors constant, we find that average levels of prescription use actually declined over the study period. PMID:8514502

  2. Lack of cool, not warm, extremes distinguishes late 20th Century climate in 979-year Tasmanian summer temperature reconstruction

    NASA Astrophysics Data System (ADS)

    Allen, K. J.; Cook, E. R.; Evans, R.; Francey, R.; Buckley, B. M.; Palmer, J. G.; Peterson, M. J.; Baker, P. J.

    2018-03-01

    Very few annually resolved millennial-length temperature reconstructions exist for the Southern Hemisphere. Here we present four 979-year reconstructions for southeastern Australia for the austral summer months of December-February. Two of the reconstructions are based on the Australian Water Availability Project dataset and two on the Berkeley Earth Surface Temperature dataset. For each climate data set, one reconstruction is based solely on Lagarostrobos franklinii (restricted reconstructions) while the other is based on multiple Tasmanian conifer species (unrestricted reconstructions). Each reconstruction calibrates ~50-60% of the variance in the temperature datasets depending on the number of tree-ring records available for the reconstruction. We found little difference in the temporal variability of the reconstructions, although extremes are amplified in the restricted reconstructions relative to the unrestricted reconstructions. The reconstructions highlight the occurrence of numerous individual years, especially in the 15th-17th Centuries, for which temperatures were comparable with those of the late 20th Century. The 1950-1999 period, however, stands out as the warmest 50-year period on average for the past 979 years, with a sustained shift away from relatively low mean temperatures, the length of which is unique in the 979-year record. The reconstructions are strongly and positively related to temperatures across the southeast of the Australian continent, negatively related to temperatures in the north and northeast of the continent, and uncorrelated with temperatures in the west. The lack of a strong relationship with temperatures across the continent highlights the necessity of a sub-regional focus for Australasian temperature reconstructions.

  3. Risk of falls in older people during fast-walking--the TASCOG study.

    PubMed

    Callisaya, M L; Blizzard, L; McGinley, J L; Srikanth, V K

    2012-07-01

    To investigate the relationship between fast-walking and falls in older people. Individuals aged 60-86 years were randomly selected from the electoral roll (n=176). Gait speed, step length, cadence and a walk ratio were recorded during preferred- and fast-walking using an instrumented walkway. Falls were recorded prospectively over 12 months. Log multinomial regression was used to estimate the relative risk of single and multiple falls associated with gait variables during fast-walking and change between preferred- and fast-walking. Covariates included age, sex, mood, physical activity, sensorimotor and cognitive measures. The risk of multiple falls was increased for those with a smaller walk ratio (shorter steps, faster cadence) during fast-walking (RR 0.92, CI 0.87, 0.97) and greater reduction in the walk ratio (smaller increase in step length, larger increase in cadence) when changing to fast-walking (RR 0.73, CI 0.63, 0.85). These gait patterns were associated with poorer physiological and cognitive function (p<0.05). A higher risk of multiple falls was also seen for those in the fastest quarter of gait speed (p=0.01) at fast-walking. A trend for better reaction time, balance, memory and physical activity for higher categories of gait speed was stronger for fallers than non-fallers (p<0.05). Tests of fast-walking may be useful in identifying older individuals at risk of multiple falls. There may be two distinct groups at risk--the frail person with short shuffling steps, and the healthy person exposed to greater risk. Copyright © 2012 Elsevier B.V. All rights reserved.

  4. Chemotaxonomy in some Mediterranean plants and implications for fossil biomarker records

    NASA Astrophysics Data System (ADS)

    Norström, Elin; Katrantsiotis, Christos; Smittenberg, Rienk H.; Kouli, Katerina

    2017-12-01

    The increasing utilization of n-alkanes as plant-derived paleo-environmental proxies calls for improved chemotaxonomic control of the modern flora in order to calibrate fossil sediment records to modern analogues. Several recent studies have investigated long-chain n-alkane concentrations and chain-length distributions in species from various vegetation biomes, but up to date, the Mediterranean flora is relatively unexplored in this respect. Here, we analyse the n-alkane concentrations and chain-length distributions in some of the most common species of the modern macchia and phrygana vegetation in south western Peloponnese, Greece. We show that the drought adapted phrygana herbs and shrubs, as well as some of the sclerophyll and gymnosperm macchia components, produce high concentrations of n-alkanes, on average more than double n-alkane production in local wetland reed vegetation. Furthermore, the chain-length distribution in the analysed plants is related to plant functionality, with longer chain lengths associated with higher drought adaptive capacities, probably as a response to long-term evolutionary processes in a moisture limited environment. Furthermore, species with relatively higher average chain lengths (ACL) showed more enriched carbon isotope composition in their tissues (δ13Cplant), suggesting a dual imprint from both physiological and biochemical drought adaptation. The findings have bearings on interpretation of fossil sedimentary biomarker records in the Mediterranean region, which is discussed in relation to a case study from Agios Floros fen, Messenian plain, Peloponnese. The 6000 year long n-alkane record from Agios Floros (ACL, δ13Cwax) is linked to the modern analogue and then evaluated through a comparison with other regional-wide as well as local climate and vegetation proxy-data. The high concentration of long chain n-alkanes in phrygana vegetation suggests a dominating imprint from this vegetation type in sedimentary archives from this ecotone.

  5. Temporal and spatial variability of frost-free seasons in the Great Lakes region of the United States

    Treesearch

    Lejiang Yu; Shiyuan Zhong; Xindi Bian; Warren E. Heilman; Jeffrey A. Andresen

    2014-01-01

    The frequency and timing of frost events and the length of the growing season are critical limiting factors in many human and natural ecosystems. This study investigates the temporal and spatial variability of the date of last spring frost (LSF), the date of first fall frost (FFF), and the length of the frost-free season (FFS) in the Great Lakes region of the United...

  6. Variables Affecting Probability of Detection in Bolt Hole Eddy Current Inspection

    NASA Astrophysics Data System (ADS)

    Lemire, H.; Krause, T. W.; Bunn, M.; Butcher, D. J.

    2009-03-01

    Physical variables affecting probability of detection (POD) in a bolt-hole eddy current inspection were examined. The POD study involved simulated bolt holes in 7075-T6 aluminum coupons representative of wing areas on CC-130 and CP-140 aircraft. The data were obtained from 24 inspectors who inspected 468 coupons, containing a subset of coupons with 45 electric discharge machined notches and 72 laboratory grown fatigue cracks located at the inner surface corner of the bi-layer structures. A comparison of physical features of cracks and notches in light of skin depth effects and probe geometry was used to identify length rather than depth as the significant variable producing signal variation. Probability of detection based on length produced similar results for the two discontinuity types, except at lengths less than 0.4 mm, where POD for cracks was found to be higher than that of notches.

  7. Non-tables look-up search algorithm for efficient H.264/AVC context-based adaptive variable length coding decoding

    NASA Astrophysics Data System (ADS)

    Han, Yishi; Luo, Zhixiao; Wang, Jianhua; Min, Zhixuan; Qin, Xinyu; Sun, Yunlong

    2014-09-01

    In general, context-based adaptive variable length coding (CAVLC) decoding in H.264/AVC standard requires frequent access to the unstructured variable length coding tables (VLCTs) and significant memory accesses are consumed. Heavy memory accesses will cause high power consumption and time delays, which are serious problems for applications in portable multimedia devices. We propose a method for high-efficiency CAVLC decoding by using a program instead of all the VLCTs. The decoded codeword from VLCTs can be obtained without any table look-up and memory access. The experimental results show that the proposed algorithm achieves 100% memory access saving and 40% decoding time saving without degrading video quality. Additionally, the proposed algorithm shows a better performance compared with conventional CAVLC decoding, such as table look-up by sequential search, table look-up by binary search, Moon's method, and Kim's method.

  8. Nonlinear Friction Compensation of Ball Screw Driven Stage Based on Variable Natural Length Spring Model and Disturbance Observer

    NASA Astrophysics Data System (ADS)

    Asaumi, Hiroyoshi; Fujimoto, Hiroshi

    Ball screw driven stages are used for industrial equipments such as machine tools and semiconductor equipments. Fast and precise positioning is necessary to enhance productivity and microfabrication technology of the system. The rolling friction of the ball screw driven stage deteriorate the positioning performance. Therefore, the control system based on the friction model is necessary. In this paper, we propose variable natural length spring model (VNLS model) as the friction model. VNLS model is simple and easy to implement as friction controller. Next, we propose multi variable natural length spring model (MVNLS model) as the friction model. MVNLS model can represent friction characteristic of the stage precisely. Moreover, the control system based on MVNLS model and disturbance observer is proposed. Finally, the simulation results and experimental results show the advantages of the proposed method.

  9. Short and Long-Term Outcomes After Surgical Procedures Lasting for More Than Six Hours.

    PubMed

    Cornellà, Natalia; Sancho, Joan; Sitges-Serra, Antonio

    2017-08-23

    Long-term all-cause mortality and dependency after complex surgical procedures have not been assessed in the framework of value-based medicine. The aim of this study was to investigate the postoperative and long-term outcomes after surgical procedures lasting for more than six hours. Retrospective cohort study of patients undergoing a first elective complex surgical procedure between 2004 and 2013. Heart and transplant surgery was excluded. Mortality and dependency from the healthcare system were selected as outcome variables. Gender, age, ASA, creatinine, albumin kinetics, complications, benign vs malignant underlying condition, number of drugs at discharge, and admission and length of stay in the ICU were recorded as predictive variables. Some 620 adult patients were included in the study. Postoperative, <1year and <5years cumulative mortality was 6.8%, 17.6% and 45%, respectively. Of patients discharged from hospital after surgery, 76% remained dependent on the healthcare system. In multivariate analysis for postoperative, <1year and <5years mortality, postoperative albumin concentration, ASA score and an ICU stay >7days, were the most significant independent predictive variables. Prolonged surgery carries a significant short and long-term mortality and disability. These data may contribute to more informed decisions taken concerning major surgery in the framework of value-based medicine.

  10. On the objective identification of flood seasons

    NASA Astrophysics Data System (ADS)

    Cunderlik, Juraj M.; Ouarda, Taha B. M. J.; BobéE, Bernard

    2004-01-01

    The determination of seasons of high and low probability of flood occurrence is a task with many practical applications in contemporary hydrology and water resources management. Flood seasons are generally identified subjectively by visually assessing the temporal distribution of flood occurrences and, then at a regional scale, verified by comparing the temporal distribution with distributions obtained at hydrologically similar neighboring sites. This approach is subjective, time consuming, and potentially unreliable. The main objective of this study is therefore to introduce a new, objective, and systematic method for the identification of flood seasons. The proposed method tests the significance of flood seasons by comparing the observed variability of flood occurrences with the theoretical flood variability in a nonseasonal model. The method also addresses the uncertainty resulting from sampling variability by quantifying the probability associated with the identified flood seasons. The performance of the method was tested on an extensive number of samples with different record lengths generated from several theoretical models of flood seasonality. The proposed approach was then applied on real data from a large set of sites with different flood regimes across Great Britain. The results show that the method can efficiently identify flood seasons from both theoretical and observed distributions of flood occurrence. The results were used for the determination of the main flood seasonality types in Great Britain.

  11. Influences of Sentence Length and Syntactic Complexity on the Speech Motor Control of Children Who Stutter

    ERIC Educational Resources Information Center

    MacPherson, Megan K.; Smith, Anne

    2013-01-01

    Purpose: To investigate the potential effects of increased sentence length and syntactic complexity on the speech motor control of children who stutter (CWS). Method: Participants repeated sentences of varied length and syntactic complexity. Kinematic measures of articulatory coordination variability and movement duration during perceptually…

  12. Covariates of Length of Stay in Residential Treatment

    ERIC Educational Resources Information Center

    Baker, Amy J. L.; Wulczyn, Fred; Dale, Nan

    2005-01-01

    This study explores variables associated with length of stay in a child welfare residential treatment center. The study followed three entry cohorts (416 boys) from admission through discharge. The researchers conducted event history analyses to examine the rates of discharge over time and the covariates of length of stay. They conducted analyses…

  13. Evaluation of three aging techniques and back-calculated growth for introduced Blue Catfish from Lake Oconee, Georgia

    USGS Publications Warehouse

    Homer, Michael D.; Peterson, James T.; Jennings, Cecil A.

    2015-01-01

    Back-calculation of length-at-age from otoliths and spines is a common technique employed in fisheries biology, but few studies have compared the precision of data collected with this method for catfish populations. We compared precision of back-calculated lengths-at-age for an introducedIctalurus furcatus (Blue Catfish) population among 3 commonly used cross-sectioning techniques. We used gillnets to collect Blue Catfish (n = 153) from Lake Oconee, GA. We estimated ages from a basal recess, articulating process, and otolith cross-section from each fish. We employed the Frasier-Lee method to back-calculate length-at-age for each fish, and compared the precision of back-calculated lengths among techniques using hierarchical linear models. Precision in age assignments was highest for otoliths (83.5%) and lowest for basal recesses (71.4%). Back-calculated lengths were variable among fish ages 1–3 for the techniques compared; otoliths and basal recesses yielded variable lengths at age 8. We concluded that otoliths and articulating processes are adequate for age estimation of Blue Catfish.

  14. Active optical zoom system

    DOEpatents

    Wick, David V.

    2005-12-20

    An active optical zoom system changes the magnification (or effective focal length) of an optical imaging system by utilizing two or more active optics in a conventional optical system. The system can create relatively large changes in system magnification with very small changes in the focal lengths of individual active elements by leveraging the optical power of the conventional optical elements (e.g., passive lenses and mirrors) surrounding the active optics. The active optics serve primarily as variable focal-length lenses or mirrors, although adding other aberrations enables increased utility. The active optics can either be LC SLMs, used in a transmissive optical zoom system, or DMs, used in a reflective optical zoom system. By appropriately designing the optical system, the variable focal-length lenses or mirrors can provide the flexibility necessary to change the overall system focal length (i.e., effective focal length), and therefore magnification, that is normally accomplished with mechanical motion in conventional zoom lenses. The active optics can provide additional flexibility by allowing magnification to occur anywhere within the FOV of the system, not just on-axis as in a conventional system.

  15. Biomechanical characteristics and speed adaptation during kick double poling on roller skis in elite cross-country skiers.

    PubMed

    Göpfert, Caroline; Holmberg, Hans-Christer; Stöggl, Thomas; Müller, Erich; Lindinger, Stefan Josef

    2013-06-01

    Recent developments in cross-country ski racing should promote the use of kick double poling. This technique, however, has not been the focus in athletes' training and has barely been investigated. The aims of the present study were to develop a function-based phase definition and to analyse speed adaptation mechanisms for kick double poling in elite cross-country skiers. Joint kinematics and pole/plantar forces were recorded in 10 athletes while performing kick double poling at three submaximal roller skiing speeds. A speed increase was associated with increases in cycle length and rate, while absolute poling and leg push-off durations shortened. Despite maintained impulses of force, the peak and average pole/leg forces increased. During double poling and leg push-off, ranges of motion of elbow flexion and extension increased (p < 0.05) and were maintained for hip/knee flexion and extension. Cycle length increase was correlated to increases in average poling force (r = 0.71) and arm swing time (r = 0.88; both p < 0.05). The main speed adaptation was achieved by changes in double poling technique; however, leg push-off showed high variability among elite skiers, thus illustrating important aspects for technique training.

  16. Associations Between Dietary Energy Density in Mothers and Growth of Breastfeeding Infants During the First 4 Months of Life.

    PubMed

    Moradi, Maedeh; Maracy, Mohammad R; Esmaillzadeh, Ahmad; Surkan, Pamela J; Azadbakht, Leila

    2018-05-31

    Despite the overwhelming impact of dietary energy density on the quality of the entire diet, no research has investigated dietary energy density among lactating mothers. Hence, the present study was undertaken to assess the influence of maternal dietary energy density during lactation on infant growth. Three hundred healthy lactating mother-infant pairs were enrolled in the study. Detailed demographic information and dietary intake data were collected from the lactating mothers. Anthropometric features such as infant weight, height, and head circumference at birth and 2 and 4 months and mother's pregnancy and postpartum weight and height were derived from health center records. Data on physical activity were reported using the International Physical Activity Questionnaire. After adjusting for confounding variables, infant weight, length, weight-for-height, and head circumference at birth, 2 months, and 4 months did not show significant differences among four dietary energy density categories (all p values > 0.01). Our study showed no association among quartiles of dietary energy density among lactating mothers and infant weight, length, weight-for-height, and head circumference growth by 2 and 4 months of age.

  17. Dichelyne (Cucullanellus) romani n. sp. (Nematoda: Cucullanidae) in notacanthid fishes from the Northeast Atlantic and Western Mediterranean.

    PubMed

    Isbert, Wolf; Montero, Francisco Esteban; Carrassón, Maite; González-Solís, David

    2015-05-01

    A new cucullanid, Dichelyne (Cucullanellus) romani n. sp. (Nematoda: Cucullanidae), is described from the digestive tract of two notacanthid fishes, Notacanthus chemnitzii Bloch and N. bonaparte Risso (Notacanthiformes: Notacanthidae), from the Northeast Atlantic and Western Mediterranean. The presence of a precloacal sucker and ten pairs of caudal papillae in males allocates it to the subgenus Cucullanellus Törnquist, 1931. The new species differs from other members of this subgenus in its larger body size, smaller spicule/body length ratio, the distribution of caudal papillae, and the position of deirids and excretory pore. Both notacanthid fishes act as definitive hosts with slightly larger nematode specimens detected in N. chemnitzii. A wide intraspecific variability was found in the distribution of caudal papillae, and in some specimens the position of deirids, excretory pore and length of intestinal caecum also varied. A complete list of all assigned species of the subgenus Cucullanellus is presented and discussed as there are several uncertainties regarding the validity and synonymy of some species. This is the first species of Dichelyne Jägerskiöld, 1902 in a notacanthid fish and one of the only two records in deep-sea fish species.

  18. Influence of an irregular surface and low light on the step variability of patients with peripheral neuropathy during level gait.

    PubMed

    Thies, Sibylle B; Richardson, James K; Demott, Trina; Ashton-Miller, James A

    2005-08-01

    Patients with peripheral neuropathy (PN) report greater difficulty walking on irregular surfaces with low light (IL) than on flat surfaces with regular lighting (FR). We tested the primary hypothesis that older PN patients would demonstrate greater step width and step width variability under IL conditions than under FR conditions. Forty-two subjects (22 male, 20 female: mean +/- S.D.: 64.7 +/- 9.8 years) with PN underwent history, physical examination, and electrodiagnostic testing. Subjects were asked to walk 10 m at a comfortable speed while kinematic and force data were measured at 100 Hz using optoelectronic markers and foot switches. Ten trials were conducted under both IL and FR conditions. Step width, time, length, and speed were calculated with a MATLAB algorithm, with the standard deviation serving as the measure of variability. The results showed that under IL, as compared to FR, conditions subjects demonstrated greater step width (197.1 +/- 40.8 mm versus 180.5 +/- 32.4 mm; P < 0.001) and step width variability (40.4 +/- 9.0 mm versus 34.5 +/- 8.4 mm; P < 0.001), step time and its variability (P < 0.001 and P = 0.003, respectively), and step length variability (P < 0.001). Average step length and gait speed decreased under IL conditions (P < 0.001 for both). Step width variability and step time variability correlated best under IL conditions with a clinical measure of PN severity and fall history, respectively. We conclude that IL conditions cause PN patients to increase the variability of their step width and other gait parameters.

  19. A High-Resolution Reconstruction of Late-Holocene Relative Sea Level in Rhode Island, USA

    NASA Astrophysics Data System (ADS)

    Stearns, R. B.; Engelhart, S. E.; Kemp, A.; Cahill, N.; Halavik, B. T.; Corbett, D. R.; Brain, M.; Hill, T. D.

    2017-12-01

    Studies on the US Atlantic and Gulf coasts have utilized salt-marsh peats and the macro- and microfossils preserved within them to reconstruct high-resolution records of relative sea level (RSL). We followed this approach to investigate spatial and temporal RSL variability in southern New England, USA, by reconstructing 3,300 years of RSL change in lower Narragansett Bay, Rhode Island. After reconnaisance of lower Narragansett Bay salt marshes, we recovered a 3.4m core at Fox Hill Marsh on Conanicut Island. We enumerated foraminiferal assemblages at 3cm intervals throughout the length of the core and we assessed trends in δ13C at 5 cm resolution. We developed a composite chronology (average resolution of ±50 years for a 1 cm slice) using 30 AMS radiocarbon dates and historical chronological markers of known age (137Cs, heavy metals, Pb isotopes, pollen). We assessed core compaction (mechanical compression) by collecting compaction-free basal-peat samples and using a published decompaction model. We employed fossil foraminifera and bulk sediment δ13C to estimate paleomarsh elevation using a Bayesian transfer function trained by a previously-published regional modern foraminiferal dataset. We combined the proxy RSL reconstruction and local tide-gauge measurements from Newport, Rhode Island (1931 CE to present) and estimated past rates of RSL change using an Errors-in-Variables Integrated Gaussian Process (EIV-IGP) model. Both basal peats and the decompaction model suggest that our RSL record is not significantly compacted. RSL rose from -3.9 m at 1250 BCE reaching -0.4 m at 1850 CE (1 mm/yr). We removed a Glacial Isostatic Adjustment (GIA) contribution of 0.9 mm/yr based on a local GPS site to facilitate comparison to regional records. The detrended sea-level reconstruction shows multiple departures from stable sea level (0 mm/yr) over the last 3,300 years and agrees with prior reconstructions from the US Atlantic coast showing evidence for sea-level changes that may be related to the Medieval Climate Anomaly (MCA) and Little Ice Age. In contrast to a similar study in Connecticut, we identified oscillations in RSL prior to the MCA. Further records in the region are required to identify whether these RSL oscillations are related to other periods of climate variability or reflect local-scale processes.

  20. Realizing the Translational Potential of Telomere Length Variation as a Tissue Based Prognostic Marker for Prostate Cancer

    DTIC Science & Technology

    2016-10-01

    Award Number: W81XWH-12-1-0545 TITLE: Realizing the Translational Potential of Telomere Length Variation as a Tissue- Based Prognostic Marker for...30 Sep 2015 - 29 Sep 2016 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Realizing the Translational Potential of Telomere Length Variation as a Tissue...HPFS), whether the combination of telomere length variability in prostate cancer cells and short telomere length in cancer-associated stromal cells is

  1. Turbulence Generation in Combustion.

    DTIC Science & Technology

    1987-07-22

    flame length . This work is summarized in this section. I1.1 Model for Turbulent Burning Velocity For a range of turbulence conditions including...Variable density effects have been added in an approximation, and an expression for the length of jet flames has been developed. The flame length expression...of jet mixing and jet flame length data using fractals, College of Engineering, Energy Report E-86-02, Comell University, Ithaca, NY, 1986. Results

  2. An Epidemiological Study of Road Traffic Accidents in Guilan Province, Northern Iran in 2012

    PubMed Central

    Mohtasham-Amiri, Zahra; Dastgiri, Saeed; Davoudi-kiakalyeh, Ali; Imani, Ali; Mollarahimi, Keyvan

    2016-01-01

    Objective: To determine the epidemiological characteristics of the road traffic injuries (RTIs) in Guilan province, northern Iran. Methods: This study was a cross-sectional study which included all of RTIs admitted to medical centers of Guilan province (northern Iran) during 2012. ICD-10 was used as diagnostic criteria. Demographic variables also injury circumstance and in hospital variables such as length of stay, time of admission, type of surgery, ICU admission, final outcome and mechanism of injury, anatomical part of injury according to Abbreviated Injury Scale (AIS) classification were derives from records by trained research team. Descriptive data is reported. The predictors of mortality were also determined. Results: The prevalence of road traffic injuries in Guilan province was 31 in 10,000 populations. Of total 7671 accidents, 5976 (77.9%) were men and 1695 (22.1%) were women. Mean age of these victims was 33.3 ± 17.289 years (32.64±16.939 for men, 35.62±18.312 for women). Most of them (32.5%) were 20-29 years old. Motorcycle-car accidents had the highest frequency followed by car-car crashes and car accidents involving pedestrians. Most of the patients (85.9%) were hospitalized and 280 injured died (3.7%). Upper extremities were the most sites of injuries. Male sex, length of hospital stay, multiple injuries and increased age were associated with road traffic accident associated mortality. Conclusion: RTIs cause enormous death and disability in this area and more road traffic preventive programs should be enforcement in these areas to reduce incidences RTI. PMID:27878129

  3. Long-term outcome of visual internal urethrotomy for the management of pediatric urethral strictures.

    PubMed

    Hafez, Ashraf T; El-Assmy, Ahmed; Dawaba, Mohamed S; Sarhan, Osama; Bazeed, Mahmoud

    2005-02-01

    We evaluated the long-term results of visual internal urethrotomy for pediatric urethral strictures to evaluate the efficacy and final outcome of this procedure in children and to evaluate the risk factors for stricture recurrence. The computerized surgical records of our hospital were reviewed to identify children who underwent visual internal urethrotomy between 1980 and 2001. Hospital and followup clinical charts were then reviewed. Many variables were analyzed, including age, etiology, length and site of the strictures, and catheter duration. Only patients with a minimum followup of 2 years were included. Regular self-catheterization was not used by any child. A total of 31 patients (mean age 11.2 years, range 2 to 18) were identified. Followup ranged from 2 to 20 years, with a mean of 6.6 years. The most common etiology for stricture formation was failed previous urethroplasty and post instrumentation (35.5% and 32.3%, respectively). The success rate after initial urethrotomy was 35.5% (11 of 31 patients). Mean interval to first recurrence was 26 months. A second urethrotomy improved the success rate of 58.1%. Eight patients required 2 or more urethrotomies, of whom half required open urethroplasty. Among the evaluated variables only stricture length shorter than 1 cm was associated with good results. Visual internal urethrotomy provides a safe first line therapeutic option for pediatric urethral strictures shorter than 1 cm, independent of etiology and location. For patients with more than 1 recurrence or with strictures longer than 1 cm, who are at high risk for recurrence after internal urethrotomy, open urethroplasty remains the treatment of choice.

  4. Multi-year longitudinal profiles of cortisol and corticosterone recovered from baleen of North Atlantic right whales (Eubalaena glacialis).

    PubMed

    Hunt, Kathleen E; Lysiak, Nadine S; Moore, Michael; Rolland, Rosalind M

    2017-12-01

    Research into stress physiology of mysticete whales has been hampered by difficulty in obtaining repeated physiological samples from individuals over time. We investigated whether multi-year longitudinal records of glucocorticoids can be reconstructed from serial sampling along full-length baleen plates (representing ∼10years of baleen growth), using baleen recovered from two female North Atlantic right whales (Eubalaena glacialis) of known reproductive history. Cortisol and corticosterone were quantified with immunoassay of subsamples taken every 4cm (representing ∼60d time intervals) along a full-length baleen plate from each female. In both whales, corticosterone was significantly elevated during known pregnancies (inferred from calf sightings and necropsy data) as compared to intercalving intervals; cortisol was significantly elevated during pregnancies in one female but not the other. Within intercalving intervals, corticosterone was significantly elevated during the first year (lactation year) and/or the second year (post-lactation year) as compared to later years of the intercalving interval, while cortisol showed more variable patterns. Cortisol occasionally showed brief high elevations ("spikes") not paralleled by corticosterone, suggesting that the two glucocorticoids might be differentially responsive to certain stressors. Generally, immunoreactive corticosterone was present in higher concentration in baleen than immunoreactive cortisol; corticosterone:cortisol ratio was usually >4 and was highly variable in both individuals. Further investigation of baleen cortisol and corticosterone profiles could prove fruitful for elucidating long-term, multi-year patterns in stress physiology of large whales, determined retrospectively from stranded or archived specimens. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Use of data mining techniques to determine and predict length of stay of cardiac patients.

    PubMed

    Hachesu, Peyman Rezaei; Ahmadi, Maryam; Alizadeh, Somayyeh; Sadoughi, Farahnaz

    2013-06-01

    Predicting the length of stay (LOS) of patients in a hospital is important in providing them with better services and higher satisfaction, as well as helping the hospital management plan and managing hospital resources as meticulously as possible. We propose applying data mining techniques to extract useful knowledge and draw an accurate model to predict the LOS of heart patients. Data were collected from patients with coronary artery disease (CAD). The patient records of 4,948 patients who had suffered CAD were included in the analysis. The techniques used are classification with three algorithms, namely, decision tree, support vector machines (SVM), and artificial neural network (ANN). LOS is the target variable, and 36 input variables are used for prediction. A confusion matrix was obtained to calculate sensitivity, specificity, and accuracy. The overall accuracy of SVM was 96.4% in the training set. Most single patients (64.3%) had an LOS ≤5 days, whereas 41.2% of married patients had an LOS >10 days. Moreover, the study showed that comorbidity states, such as lung disorders and hemorrhage with drug consumption have an impact on long LOS. The presence of comorbidities, an ejection fraction <2, being a current smoker, and having social security type insurance in coronary artery patients led to longer LOS than other subjects. All three algorithms are able to predict LOS with various degrees of accuracy. The findings demonstrated that the SVM was the best fit. There was a significant tendency for LOS to be longer in patients with lung or respiratory disorders and high blood pressure.

  6. Determinants of change in physical activity during moderate-to-severe COPD exacerbation

    PubMed Central

    Esteban, Cristóbal; Quintana, José M; Garcia-Gutierrez, Susana; Anton-Ladislao, Ane; Gonzalez, Nerea; Baré, Marisa; Fernández de Larrea, Nerea; Rivas-Ruiz, Francisco

    2016-01-01

    Background Data are scarce on patient physical activity (PA) level during exacerbations of chronic obstructive pulmonary disease (eCOPD). The objective of the study was to evaluate the level and determinants of change in PA during an eCOPD. Materials and methods We conducted a prospective cohort study with recruitment from emergency departments (EDs) of 16 participating hospitals from June 2008 to September 2010. Data were recorded on socioeconomic characteristics, dyspnea, forced expiratory volume in 1 second (FEV1%), comorbidities, health-related quality of life, factors related to exacerbation, and PA in a stable clinical condition and during the eCOPD episode. Results We evaluated 2,487 patients. Common factors related to the change in PA during hospital admission or 7 days after discharge to home from the ED were lower PA at baseline and during the first 24 hours after the index evaluation. Age, quality of life, living alone, length of hospital stay, and use of anticholinergic or systemic corticosteroids in treating the exacerbation were associated with the change in PA among hospitalized patients. Predictors of change among patients not admitted to hospital were baseline FEV1% and dyspnea at rest on ED arrival. Conclusion Among the patients evaluated in an ED for an eCOPD, the level and change in PA was markedly variable. Factors associated with exacerbation (PA 24 hours after admission, medication during admission, and length of hospital stay) and variables reflecting patients’ stable clinical condition (low level of PA, age, quality of life, FEV1%) are predictors of the change in PA during a moderate-to-severe eCOPD. PMID:26893555

  7. Climate-related relative sea-level changes from Chesapeake Bay, U.S. Atlantic coast

    NASA Astrophysics Data System (ADS)

    Shaw, Timothy; Horton, Benjamin; Kemp, Andrew; Cahill, Niamh; Mann, Michael; Engelhart, Simon; Kopp, Robert; Brain, Matthew; Clear, Jennifer; Corbett, Reide; Nikitina, Daria; Garcia-Artola, Ane; Walker, Jennifer

    2017-04-01

    Proxy-based reconstructions of relative sea level (RSL) from the coastlines of the North Atlantic have revealed spatial and temporal variability in the rates of RSL rise during periods of known Late-Holocene climatic variability. Regional driving mechanisms for such variability include glacial isostatic adjustment, static-equilibrium of land-ice changes and/or ocean dynamic effects as well as more localized factors (e.g. sediment compaction and tidal range change). We present a 4000-year RSL reconstruction from salt-marsh sediments of the Chesapeake Bay using a foraminiferal-based transfer function and a composite chronology. A local contemporary training set of foraminifera was developed to calibrate fossil counterparts and provide estimates of paleo marsh elevation with vertical uncertainties of ±0.06m. A composite chronology combining 30 radiocarbon dates, pollen chronohorizons, regional pollution histories, and short-lived radionuclides was placed into a Bayesian age-depth framework yielding low temporal uncertainties averaging 40 years. A compression-only geotechnical model was applied to decompact the RSL record. We coupled the proxy reconstruction with direct observations from nearby tide gauge records before rates of RSL rise were quantified through application of an Errors-In-Variables Integrated Gaussian Process model. The RSL history for Chesapeake Bay shows 6 m of rise since 2000 BCE. Between 2000 BCE and 1300 BCE, rates of RSL increasing to 1.4 mm/yr precede a significant decrease to 0.8 mm/yr at 700 BCE. This minimum coincides with widespread climate cooling identified in multiple paleoclimate archives of the North Atlantic. An increase in the rate of RSL rise to 2.1 mm/yr at 200 CE similarly precedes a decrease in the rate of RSL rise at 1450 CE (1.3 mm/yr) that coincides with the Little Ice Age. Modern rates of RSL rise (3.6 mm/yr) are the fastest observed in the past 4000 years. The temporal length and decadal resolution of the RSL reconstruction further reconciles the response of sea levels to late Holocene climate variability.

  8. Use of the SLW index to calculate growth function in the sea cucumber Isostichopus badionotus

    PubMed Central

    Poot-Salazar, Alicia; Hernández-Flores, Álvaro; Ardisson, Pedro-Luis

    2014-01-01

    Age and growth analysis is essential to fisheries management. Indirect methods to calculate growth are widely used; however, length frequency data analysis in sea cucumbers is complicated by high data variability caused by body wall elasticity. Here we calculated Isostichopus badionotus parameters of the von Bertalanffy growth function. In order to address bias produced by body wall elasticity, we compared the performance of four measurements and one compound index that combines different biometric parameters: the square root of the length-width product (SLW). Results showed that variability in length data due to body wall elasticity was controlled by using body length (Le) from the SLW compound index. Growth in I. badionotus follows a negative allometric tendency. Slow or zero growth periods were observed during October and November, when weather conditions were adverse. PMID:24909262

  9. Design of a variable-focal-length optical system

    NASA Technical Reports Server (NTRS)

    Ricks, D.; Shannon, R. R.

    1984-01-01

    Requirements to place an entire optical system with a variable focal length ranging from 20 to 200 cm within a overall length somewhat less than 100 cm placed severe restrictions on the design of a zoom lens suitable for use on a comet explorer. The requirements of a wavelength range of 0.4 to 1.0 microns produced even greater limitations on the possibilities for a design that included a catadioptric (using mirrors and glass) front and followed by a zooming refractive portion. Capabilities available commercial zoom lenses as well as patents of optical systems are reviewed. Preliminary designs of the refractive optics zoom lens and the catadioptric system are presented and evaluated. Of the two, the latter probably has the best chance of success, so long as the shortest focal lengths are not really needed.

  10. The Effects of Angular Orientation on Flame Spread over Thin Materials

    DTIC Science & Technology

    1999-12-01

    Notation 7 5 Upward Spread With Burnout 8 6a Observed Flame Lengths on Napkins, Increments 2.5 cm 9 6b Observed Flame Lengths on Pet Film, Increments...Frequency of Extinguishment During Flame Spread 21 15 Flame Spread Velocity 21 VI 16 Flame Length Measured Parallel to the Surface 22 17 Comparison of... flame length (Lf) were measured from a video recording of the test. Despite erratic burn fronts with discontinuous flaming regions, the maximum

  11. Daily Temperature and Precipitation Data for 223 Former-USSR Stations (NDP-040)

    DOE Data Explorer

    Razuvaev, V. N. [Russian Research Institute of Hydrometeorological Information-World Data Centre; Apasova, E. B. [Russian Research Institute of Hydrometeorological Information-World Data Centre; Martuganov, R. A. [Russian Research Institute of Hydrometeorological Information-World Data Centre

    1990-01-01

    The stations in this dataset are considered by RIHMI to comprise one of the best networks suitable for temperature and precipitation monitoring over the the former-USSR. Factors involved in choosing these 223 stations included length or record, amount of missing data, and achieving reasonably good geographic coverage. There are indeed many more stations with daily data over this part of the world, and hundreds more station records are available through NOAA's Global Historical Climatology Network - Daily (GHCND) database. The 223 stations comprising this database are included in GHCND, but different data processing, updating, and quality assurance methods/checks mean that the agreement between records will vary depending on the station. The relative quality and accuracy of the common station records in the two databases also cannot be easily assessed. As of this writing, most of the common stations contained in the GHCND have more recent records, but not necessarily records starting as early as the records available here. This database contains four variables: daily mean, minimum, and maximum temperature, and daily total precipitation (liquid equivalent). Temperature were taken three times a day from 1881-1935, four times a day from 1936-65, and eight times a day since 1966. Daily mean temperature is defined as the average of all observations for each calendar day. Daily maximum/minimum temperatures are derived from maximum/minimum thermometer measurements. See the measurement description file for further details. Daily precipitation totals are also available (to the nearest tenth of a millimeter) for each station. Throughout the record, daily precipitation is defined as the total amount of precipitation recorded during a 24-h period, snowfall being converted to a liquid total by melting the snow in the gauge. From 1936 on, rain gauges were checked several times each day; the cumulative total of all observations during a calendar day was presumably used as the daily total. Again, see the measurement description file for further details.

  12. Description of individual data items and codes in CRIB

    USGS Publications Warehouse

    Keefer, Eleanor K.; Calkins, James Alfred

    1978-01-01

    The U.S. Geological Survey's Computerized Resources Information Bank (CRIB) is being made available for public use through the computer facilities of the University of Oklahoma and the General Electric Company, U.S.A. The use of General Electric's worldwide information-services network provides access to the CRIB file to a worldwide clientele. This manual, which consists of two chapters, is intended as a guide to users who wish to interrogate the file. Chapter A contains a description of the CRIB file, information on the use of the GIPSY retrieval system, and a description of the General Electric MARK III Service. Chapter B contains a description of the individual data items in the CRIB record as well as code lists. CRIB consists of a set of variable-length records on the metallic and nonmetallic mineral resources of the United States and other countries. At present, 31,645 records in the master file are being made available. The record contains information on mineral deposits and mineral commodities. Some topics covered are: deposit name, location, commodity information, description of deposit, geology, production, reserves, potential resources, and references. The data are processed by the GIPSY program, which maintains the data file and builds, updates, searches, and prints the records using simple yet versatile command statements. Searching and selecting records is accomplished by specifying the presence, absence, or content of any element of information in the record; these specifications can be logically linked to prepare sophisticated search strategies. Output is available in the form of the complete record, a listing of selected parts of the record, or fixed-field tabulations. The General Electric MARK III Service is a computerized information services network operating internationally by land lines, satellites, and undersea cables. The service is available by local telephone to 500 cities in North America, Western Europe, Australia, Southeast Asia, Japan, and Saudi Arabia. An interface called the 'foreground driver' is used to link the GIPSY program to the General Electric system.

  13. Automated analysis of two-dimensional positions and body lengths of earthworms (Oligochaeta); MimizuTrack.

    PubMed

    Kodama, Naomi; Kimura, Toshifumi; Yonemura, Seiichiro; Kaneda, Satoshi; Ohashi, Mizue; Ikeno, Hidetoshi

    2014-01-01

    Earthworms are important soil macrofauna inhabiting almost all ecosystems. Their biomass is large and their burrowing and ingestion of soils alters soil physicochemical properties. Because of their large biomass, earthworms are regarded as an indicator of "soil heath". However, primarily because the difficulties in quantifying their behavior, the extent of their impact on soil material flow dynamics and soil health is poorly understood. Image data, with the aid of image processing tools, are a powerful tool in quantifying the movements of objects. Image data sets are often very large and time-consuming to analyze, especially when continuously recorded and manually processed. We aimed to develop a system to quantify earthworm movement from video recordings. Our newly developed program successfully tracked the two-dimensional positions of three separate parts of the earthworm and simultaneously output the change in its body length. From the output data, we calculated the velocity of the earthworm's movement. Our program processed the image data three times faster than the manual tracking system. To date, there are no existing systems to quantify earthworm activity from continuously recorded image data. The system developed in this study will reduce input time by a factor of three compared with manual data entry and will reduce errors involved in quantifying large data sets. Furthermore, it will provide more reliable measured values, although the program is still a prototype that needs further testing and improvement. Combined with other techniques, such as measuring metabolic gas emissions from earthworm bodies, this program could provide continuous observations of earthworm behavior in response to environmental variables under laboratory conditions. In the future, this standardized method will be applied to other animals, and the quantified earthworm movement will be incorporated into models of soil material flow dynamics or behavior in response to chemical substances present in the soil.

  14. Early intervention of negative pressure wound therapy using Vacuum-Assisted Closure in trauma patients: impact on hospital length of stay and cost.

    PubMed

    Kaplan, Mark; Daly, Darron; Stemkowski, Stephen

    2009-03-01

    The cost of treating complex traumatic wounds is substantial because of trauma severity, potential for infection, and delayed closure. Negative pressure wound therapy using reticulated open cell foam (NPWT/ROCF) as delivered by Vacuum-Assisted Closure* (KCI Licensing, Inc, San Antonio, Texas) is an established, viable option for treating traumatic wounds. The authors used retrospective data to study the clinical and cost-effective benefits of using NPWT/ROCF early on day 1 or day 2 of treatment for traumatic wounds as compared with using it late (on day 3 or later). Hospital data records from trauma wound patients treated with NPWT/ROCF were retrospectively analyzed. Data were subdivided into 2 groups based on start of treatment. The group of patients treated on day 1 or 2 of their hospital stay was referred to as the early group, and that composed of patients treated on day 3 or later as the late group. Clinical and cost-effective metrics were compared between the 2 groups. For the early group, 518 patient records were included; 1000 records were reviewed for the late group. Early-group patients had fewer hospital inpatient days (10.6 vs 20.6 days; P < .0001), fewer treatment days (5.1 vs 6.0 days; P = .0498), shorter intensive care unit (ICU) stays (5.3 vs 12.4 days; P < .0001), and higher ICU admission rates (51.5 vs 44.5%; P = .0091) than the late group. Compared with late-group patients, early-group patients had lower total and variable costs per patient discharge ($43,956 vs $32,175; P < .0001 and $22,891 vs $15,805; P < .0001, respectively). Acute-care trauma wound patients receiving early NPWT/ROCF demonstrated significant reductions in length of stay, treatment days, and ICU stay, which resulted in significant reduced patient treatment costs. These results indicate that early intervention with NPWT/ROCF has potential clinical and cost-effective benefits for the treatment of traumatic wounds.

  15. Assessing extreme droughts in North-East Spain from rogation ceremonies

    NASA Astrophysics Data System (ADS)

    Cuadrat, José M.; Barriendos, Mariano; Tejedor, Ernesto; Ángel Saz, Miguel; Serrano, Roberto

    2014-05-01

    Among the different meteorological hazards, droughts are those with the highest socio-economical impact on the Iberian Peninsula. In the present work, drought events that occurred in North-East Spain during the period 1600-1900 have been analysed, using historical information. The abundant documentation available in historical archives and the detail of the meteorological event records allows us the systematic and continuous summary of the drought events from 16th to 19th centuries. Rogation (ceremonies to ask God for rain: pro-pluvia, or to stop raining: pro-serenitate) analysis is an effective method to derive information about climate extremes from documentary sources. These documents are homogeneous information that permit the reconstruction of drought frequency series and create continuous drought indices. Weighted annual sum by levels has been a widespread technique to analyze such data but this analysis is liable to be biased to spring values as these ceremonies are strongly related to farming activities and crop development. The analysis of the length of pro-pluvia periods (the time span during which rogations are carried out in relation to a drought event) and the combination of annual and seasonal information offers a more objective criterion for the analysis of the drought periods and an increase in the resolution of the study. Two drought maxima appear during the 1650-1675 and 1765-1795 periods, characterized by rogations during almost all the year, with a middle stage (1676-1710) when droughts were less frequent and their length shortened. Results indicate that drought evolution during the past four centuries often coincides in time with the evolution recorded in other Mediterranean areas. Between the sixteenth and nineteenth centuries the most important droughts were recorded in the last quarter of the eighteenth century, which coincided with a period of high climatic variability known as the "Maldá" anomaly. In general, the eighteenth century was drier than the seventeenth and nineteenth centuries.

  16. An EMA analysis of the effect of increasing word length on consonant production in apraxia of speech: a case study.

    PubMed

    Bartle, Carly J; Goozée, Justine V; Murdoch, Bruce E

    2007-03-01

    The effect of increasing word length on the articulatory dynamics (i.e. duration, distance, maximum acceleration, maximum deceleration, and maximum velocity) of consonant production in acquired apraxia of speech was investigated using electromagnetic articulography (EMA). Tongue-tip and tongue-back movement of one apraxic patient was recorded using the AG-200 EMA system during word-initial consonant productions in one, two, and three syllable words. Significantly deviant articulatory parameters were recorded for each of the target consonants during one, two, and three syllables words. Word length effects were most evident during the release phase of target consonant productions. The results are discussed with respect to theories of speech motor control as they relate to AOS.

  17. Finite-Length Diocotron Modes in a Non-neutral Plasma Column

    NASA Astrophysics Data System (ADS)

    Walsh, Daniel; Dubin, Daniel

    2017-10-01

    Diocotron modes are 2D distortions of a non-neutral plasma column that propagate azimuthally via E × B drifts. While the infinite-length theory of diocotron modes is well-understood for arbitrary azimuthal mode number l, the finite-length mode frequency is less developed (with some exceptions), and is naturally of relevance to experiments. In this poster, we present an approach to address finite length effects, such as temperature dependence of the mode frequency. We use a bounce-averaged solution to the Vlasov Equation, in which the Vlasov Equation is solved using action-angle variables of the unperturbed Hamiltonian. We write the distribution function as a Fourier series in the bounce-angle variable ψ, keeping only the bounce-averaged term. We demonstrate a numerical solution to this equation for a realistic plasma with a finite Debye Length, compare to the existing l = 1 theory, and discuss possible extensions of the existing theory to l ≠ 1 . Supported by NSF/DOE Partnership Grants PHY1414570 and DESC0002451.

  18. Prostate Cancer Cell Telomere Length Variability and Stromal Cell Telomere Length as Prognostic Markers for Metastasis and Death

    PubMed Central

    Heaphy, Christopher M.; Yoon, Ghil Suk; Peskoe, Sarah B.; Joshu, Corinne E.; Lee, Thomas K.; Giovannucci, Edward; Mucci, Lorelei A.; Kenfield, Stacey A.; Stampfer, Meir J.; Hicks, Jessica L.; De Marzo, Angelo M.; Platz, Elizabeth A.; Meeker, Alan K.

    2013-01-01

    Current prognostic indicators are imperfect predictors of outcome in men with clinicallylocalized prostate cancer. Thus, tissue-based markers are urgently needed to improve treatment and surveillance decision-making. Given that shortened telomeres enhance chromosomal instability and such instability is a hallmark of metastatic lesions, we hypothesized that alterations in telomere length in the primary cancer would predict risk of progression to metastasis and prostate cancer death. To test this hypothesis, we conducted a prospective cohort study of 596 surgically treated men who participated in the ongoing Health Professionals Follow-up Study. Men who had the combination of more variable telomere length among prostate cancer cells (cell-to-cell) and shorter telomere length in prostate cancer-associated stromal cells were substantially more likely to progress to metastasis or die of their prostate cancer. These findings point to the translational potential of this telomere biomarker for prognostication and risk stratification for individualized therapeutic and surveillance strategies. PMID:23779129

  19. Reproducibility of Clathromorphum compactum coralline algal Mg/Ca ratios and comparison to high-resolution sea surface temperature data

    NASA Astrophysics Data System (ADS)

    Hetzinger, S.; Halfar, J.; Kronz, A.; Simon, K.; Adey, W. H.; Steneck, R. S.

    2018-01-01

    The potential of crustose coralline algae as high-resolution archives of past ocean variability in mid- to high-latitudes has only recently been recognized. Few comparisons of coralline algal proxies, such as temperature-dependent algal magnesium to calcium (Mg/Ca) ratios, with in situ-measured surface ocean data exist, even rarer are well replicated records from individual sites. We present Mg/Ca records from nine coralline algal specimens (Clathromorphum compactum) from a single site in the Gulf of Maine, North Atlantic. Sections from algal mounds were analyzed using Laser Ablation-Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) yielding individual Mg/Ca records of up to 30 years in length. We first test intra- and intersample signal replication and show that algal Mg/Ca ratios are reproducible along several transects within individual sample specimens and between different samples from the same study site. In addition, LA-ICP-MS-derived Mg/Ca ratios are compared to electron microprobe (EMP) analyzed data on the longest-lived specimens and were found to be statistically commensurable. Second, we evaluate whether relationships between algal-based SST reconstructions and in situ temperature data can be improved by averaging Mg/Ca records from multiple algal specimens (intersample averages). We found that intersample averages yield stronger relationships to sea surface temperature (SST) data than Mg/Ca records derived from individual samples alone. Thus, Mg/Ca-based paleotemperature reconstructions from coralline algae can benefit from using multiple samples per site, and can expand temperature proxy precision from seasonal to monthly.

  20. Insights into new-onset atrial fibrillation following open heart surgery and implications for type II atrial flutter.

    PubMed

    Sadrpour, Shervin A; Srinivasan, Deepa; Bhimani, Ashish A; Lee, Seungyup; Ryu, Kyungmoo; Cakulev, Ivan; Khrestian, Celeen M; Markowitz, Alan H; Waldo, Albert L; Sahadevan, Jayakumar

    2015-12-01

    Postoperative atrial fibrillation (POAF), new-onset AF after open heart surgery (OHS), is thought to be related to pericarditis. Based on AF studies in the canine sterile pericarditis model, we hypothesized that POAF in patients after OHS may be associated with a rapid, regular rhythm in the left atrium (LA), suggestive of an LA driver maintaining AF. The aim of this study was to test the hypothesis that in patients with POAF, atrial electrograms (AEGs) recorded from at least one of the two carefully selected LA sites would manifest a rapid, regular rhythm with AEGs of short cycle length (CL) and constant morphology, but a selected right atrial (RA) site would manifest AEGs with irregular CLs and variable morphology. In 44 patients undergoing OHS, AEGs recorded from the epicardial surface of the RA, the LA portion of Bachmann's bundle, and the posterior LA during sustained AF were analysed for regularity of CL and morphology. Sustained AF occurred in 15 of 44 patients. Atrial electrograms were recorded in 11 of 15 patients; 8 of 11 had rapid, regular activation with constant morphology recorded from at least one LA site; no regular AEG sites were present in 3 of 11 patients. Atrial electrograms recorded during sustained POAF frequently demonstrated rapid, regular activation in at least one LA site, consistent with a driver maintaining AF. Published by Oxford University Press on behalf of the European Society of Cardiology 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  1. Fast, deep record length, time-resolved visible spectroscopy of plasmas using fiber grids

    NASA Astrophysics Data System (ADS)

    Brockington, Samuel; Case, Andrew; Cruz, Edward; Witherspoon, F. Douglas; Horton, Robert; Klauser, Ruth; Hwang, D. Q.

    2016-10-01

    HyperV Technologies is developing a fiber-coupled, deep-record-length, low-light camera head for performing high time resolution spectroscopy on visible emission from plasma events. New solid-state Silicon Photo-Multiplier (SiPM) chips are capable of single photon event detection and high speed data acquisition. By coupling the output of a spectrometer to an imaging fiber bundle connected to a bank of amplified SiPMs, time-resolved spectroscopic imagers of 100 to 1,000 pixels can be constructed. Target pixel performance is 10 Megaframes/sec with record lengths of up to 256,000 frames yielding 25.6 milliseconds of record at10 Megasamples/sec resolution. Pixel resolutions of 8 to 12 bits are pos- sible. Pixel pitch can be refined by using grids of 100 μm to 1000 μm diameter fibers. A prototype 32-pixel spectroscopic imager employing this technique was constructed and successfully tested at the University of California at Davis Compact Toroid Injection Experiment (CTIX) as a full demonstration of the concept. Experimental results will be dis-cussed, along with future plans for the Phase 2 project, and potential applications to plasma experiments . Work supported by USDOE SBIR Grant DE-SC0013801.

  2. Optimized coral reconstructions of the Indian Ocean Dipole: An assessment of location and length considerations

    NASA Astrophysics Data System (ADS)

    Abram, Nerilie J.; Dixon, Bronwyn C.; Rosevear, Madelaine G.; Plunkett, Benjamin; Gagan, Michael K.; Hantoro, Wahyoe S.; Phipps, Steven J.

    2015-10-01

    The Indian Ocean Dipole (IOD; or Indian Ocean Zonal Mode) is a coupled ocean-atmosphere climate oscillation that has profound impacts on rainfall distribution across the Indian Ocean region. Instrumental records provide a reliable representation of IOD behavior since 1958, while coral reconstructions currently extend the IOD history back to 1846. Large fluctuations in the number and intensity of positive IOD events over time are evident in these records, but it is unclear to what extent this represents multidecadal modulation of the IOD or an anthropogenically forced change in IOD behavior. In this study we explore the suitability of coral records from single-site locations in the equatorial Indian Ocean for capturing information about the occurrence and magnitude of positive IOD (pIOD) events. We find that the optimum location for coral reconstructions of the IOD occurs in the southeastern equatorial Indian Ocean, along the coast of Java and Sumatra between ~3 and 7°S. Here the strong ocean cooling and atmospheric drying during pIOD events are unambiguously recorded in coral oxygen isotope records, which capture up to 50% of IOD variance. Unforced experiments with coupled climate models suggest that potential biases in coral estimates of pIOD frequency are skewed toward overestimating pIOD recurrence intervals and become larger with shorter reconstruction windows and longer pIOD recurrence times. Model output also supports the assumption of stationarity in sea surface temperature relationships in the optimum IOD location that is necessary for paleoclimate reconstructions. This study provides a targeted framework for the future generation of paleoclimate records, including optimized coral reconstructions of past IOD variability.

  3. A Satellite-Derived Climate-Quality Data Record of the Clear-Sky Surface Temperature of the Greenland Ice Sheet

    NASA Technical Reports Server (NTRS)

    Hall, Dorothy K.; Comiso, Josefino C.; DiGirolamo, Nicolo E.; Shuman, Christopher A.; Key, Jeffrey R.; Koenig, Lora S.

    2011-01-01

    We have developed a climate-quality data record of the clear-sky surface temperature of the Greenland Ice Sheet using the Moderate-Resolution Imaging Spectroradiometer (MODIS) Terra ice-surface temperature (1ST) algorithm. A climate-data record (CDR) is a time series of measurements of sufficient length, consistency, and continuity to determine climate variability and change. We present daily and monthly Terra MODIS ISTs of the Greenland Ice Sheet beginning on 1 March 2000 and continuing through 31 December 2010 at 6.25-km spatial resolution on a polar stereographic grid within +/-3 hours of 17:00Z or 2:00 PM Local Solar Time. Preliminary validation of the ISTs at Summit Camp, Greenland, during the 2008-09 winter, shows that there is a cold bias using the MODIS IST which underestimates the measured surface temperature by approximately 3 C when temperatures range from approximately -50 C to approximately -35 C. The ultimate goal is to develop a CDR that starts in 1981 with the Advanced Very High Resolution (AVHRR) Polar Pathfinder (APP) dataset and continues with MODIS data from 2000 to the present. Differences in the APP and MODIS cloud masks have so far precluded the current IST records from spanning both the APP and MODIS IST time series in a seamless manner though this will be revisited when the APP dataset has been reprocessed. The Greenland IST climate-quality data record is suitable for continuation using future Visible Infrared Imager Radiometer Suite (VIIRS) data and will be elevated in status to a CDR when at least 9 more years of climate-quality data become available either from MODIS Terra or Aqua, or from the VIIRS. The complete MODIS IST data record will be available online in the summer of 2011.

  4. Evaluation of the streamflow-gaging network of Texas and a proposed core network

    USGS Publications Warehouse

    Slade, Raymond M.; Howard, Teresa; Anaya, Roberto

    2001-01-01

    The U.S. Geological Survey streamflowgaging network in Texas is operated as part of the National Streamgaging Program and is jointly funded by the Geological Survey and Federal, State, and local agencies. This report documents an evaluation of the existing (as of October 1, 1999) network with regard to four major objectives of streamflow data; and on the basis of that evaluation, proposes a core network of streamflowgaging stations that best meets those objectives. The objectives are (1) regionalization (estimate flows or flow characteristics at ungaged sites in 11 hydrologically similar regions), (2) major flow (obtain flow rates and volumes in large streams), (3) outflow from the State (account for streamflow leaving the State), and (4) streamflow conditions assessment (assess current conditions with regard to long-term data, and define temporal trends in flow). The network analysis resulted in a proposed core network of 263 stations. Of those 263 stations, 43 were discontinued as of October 1, 1999, and 15 were partial-record stations. Fifty-five of the proposed core-network stations meet two of the four major objectives, 16 stations meet three objectives, and 1 station meets all four. One-hundred eighty-five stations with a median record length of 33 years were selected to meet the regionalization objective. Ninety-two stations with a median record length of about 62 years were selected to meet the major-flow objective. Twenty-six stations with a median record length of 59 years were selected to meet the outflow from the State objective. Fifty stations with a median record length of 53 years were selected to meet the streamflow conditions assessment objective.

  5. Flagellar Synchronization Is a Simple Alternative to Cell Cycle Synchronization for Ciliary and Flagellar Studies

    PubMed Central

    Dutta, Soumita

    2017-01-01

    ABSTRACT The unicellular green alga Chlamydomonas reinhardtii is an ideal model organism for studies of ciliary function and assembly. In assays for biological and biochemical effects of various factors on flagellar structure and function, synchronous culture is advantageous for minimizing variability. Here, we have characterized a method in which 100% synchronization is achieved with respect to flagellar length but not with respect to the cell cycle. The method requires inducing flagellar regeneration by amputation of the entire cell population and limiting regeneration time. This results in a maximally homogeneous distribution of flagellar lengths at 3 h postamputation. We found that time-limiting new protein synthesis during flagellar synchronization limits variability in the unassembled pool of limiting flagellar protein and variability in flagellar length without affecting the range of cell volumes. We also found that long- and short-flagella mutants that regenerate normally require longer and shorter synchronization times, respectively. By minimizing flagellar length variability using a simple method requiring only hours and no changes in media, flagellar synchronization facilitates the detection of small changes in flagellar length resulting from both chemical and genetic perturbations in Chlamydomonas. This method increases our ability to probe the basic biology of ciliary size regulation and related disease etiologies. IMPORTANCE Cilia and flagella are highly conserved antenna-like organelles that found in nearly all mammalian cell types. They perform sensory and motile functions contributing to numerous physiological and developmental processes. Defects in their assembly and function are implicated in a wide range of human diseases ranging from retinal degeneration to cancer. Chlamydomonas reinhardtii is an algal model system for studying mammalian cilium formation and function. Here, we report a simple synchronization method that allows detection of small changes in ciliary length by minimizing variability in the population. We find that this method alters the key relationship between cell size and the amount of protein accumulated for flagellar growth. This provides a rapid alternative to traditional methods of cell synchronization for uncovering novel regulators of cilia. PMID:28289724

  6. Flagellar Synchronization Is a Simple Alternative to Cell Cycle Synchronization for Ciliary and Flagellar Studies.

    PubMed

    Dutta, Soumita; Avasthi, Prachee

    2017-01-01

    The unicellular green alga Chlamydomonas reinhardtii is an ideal model organism for studies of ciliary function and assembly. In assays for biological and biochemical effects of various factors on flagellar structure and function, synchronous culture is advantageous for minimizing variability. Here, we have characterized a method in which 100% synchronization is achieved with respect to flagellar length but not with respect to the cell cycle. The method requires inducing flagellar regeneration by amputation of the entire cell population and limiting regeneration time. This results in a maximally homogeneous distribution of flagellar lengths at 3 h postamputation. We found that time-limiting new protein synthesis during flagellar synchronization limits variability in the unassembled pool of limiting flagellar protein and variability in flagellar length without affecting the range of cell volumes. We also found that long- and short-flagella mutants that regenerate normally require longer and shorter synchronization times, respectively. By minimizing flagellar length variability using a simple method requiring only hours and no changes in media, flagellar synchronization facilitates the detection of small changes in flagellar length resulting from both chemical and genetic perturbations in Chlamydomonas . This method increases our ability to probe the basic biology of ciliary size regulation and related disease etiologies. IMPORTANCE Cilia and flagella are highly conserved antenna-like organelles that found in nearly all mammalian cell types. They perform sensory and motile functions contributing to numerous physiological and developmental processes. Defects in their assembly and function are implicated in a wide range of human diseases ranging from retinal degeneration to cancer. Chlamydomonas reinhardtii is an algal model system for studying mammalian cilium formation and function. Here, we report a simple synchronization method that allows detection of small changes in ciliary length by minimizing variability in the population. We find that this method alters the key relationship between cell size and the amount of protein accumulated for flagellar growth. This provides a rapid alternative to traditional methods of cell synchronization for uncovering novel regulators of cilia.

  7. 38 CFR 43.42 - Retention and access requirements for records.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Length of retention period. (1) Except as otherwise provided, records must be retained for three years... period, the records must be retained until completion of the action and resolution of all issues which... recordkeeping, awarding agencies may make special arrangements with grantees and subgrantees to retain any...

  8. 45 CFR 2541.420 - Retention and access requirements for records.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) Length of retention period. (1) Except as otherwise provided, records must be retained for three years... period, the records must be retained until completion of the action and resolution of all issues which... recordkeeping, awarding agencies may make special arrangements with grantees and subgrantees to retain any...

  9. The Ultrasensitivity of Living Polymers

    NASA Astrophysics Data System (ADS)

    O'Shaughnessy, Ben; Vavylonis, Dimitrios

    2003-03-01

    Synthetic and biological living polymers are self-assembling chains whose chain length distributions (CLDs) are dynamic. We show these dynamics are ultrasensitive: Even a small perturbation (e.g., temperature jump) nonlinearly distorts the CLD, eliminating or massively augmenting short chains. The origin is fast relaxation of mass variables (mean chain length, monomer concentration) which perturbs CLD shape variables before these can relax via slow chain growth rate fluctuations. Viscosity relaxation predictions agree with experiments on the best-studied synthetic system, α-methylstyrene.

  10. Millennial- to century-scale variability in Gulf of Mexico Holocene climate records

    USGS Publications Warehouse

    Poore, R.Z.; Dowsett, H.J.; Verardo, S.; Quinn, T.M.

    2003-01-01

    Proxy records from two piston cores in the Gulf of Mexico (GOM) provide a detailed (50-100 year resolution) record of climate variability over the last 14,000 years. Long-term (millennial-scale) trends and changes are related to the transition from glacial to interglacial conditions and movement of the average position of the Intertropical Convergence Zone (ITCZ) related to orbital forcing. The ??18O of the surface-dwelling planktic foraminifer Globigerinoides ruber show negative excursions between 14 and 10.2 ka (radiocarbon years) that reflect influx of meltwater into the western GOM during melting of the Laurentide Ice Sheet. The relative abundance of the planktic foraminifer Globigerinoides sacculifer is related to transport of Caribbean water into the GOM. Maximum transport of Caribbean surface waters and moisture into the GOM associated with a northward migration of the average position of the ITCZ occurs between about 6.5 and 4.5 ka. In addition, abundance variations of G. sacculifer show century-scale variability throughout most of the Holocene. The GOM record is consistent with records from other areas, suggesting that century-scale variability is a pervasive feature of Holocene climate. The frequency of several cycles in the climate records is similar to cycles identified in proxy records of solar variability, indicating that at least some of the century-scale climate variability during the Holocene is due to external (solar) forcing.

  11. Conventional heart rate variability analysis of ambulatory electrocardiographic recordings fails to predict imminent ventricular fibrillation

    NASA Technical Reports Server (NTRS)

    Vybiral, T.; Glaeser, D. H.; Goldberger, A. L.; Rigney, D. R.; Hess, K. R.; Mietus, J.; Skinner, J. E.; Francis, M.; Pratt, C. M.

    1993-01-01

    OBJECTIVES. The purpose of this report was to study heart rate variability in Holter recordings of patients who experienced ventricular fibrillation during the recording. BACKGROUND. Decreased heart rate variability is recognized as a long-term predictor of overall and arrhythmic death after myocardial infarction. It was therefore postulated that heart rate variability would be lowest when measured immediately before ventricular fibrillation. METHODS. Conventional indexes of heart rate variability were calculated from Holter recordings of 24 patients with structural heart disease who had ventricular fibrillation during monitoring. The control group consisted of 19 patients with coronary artery disease, of comparable age and left ventricular ejection fraction, who had nonsustained ventricular tachycardia but no ventricular fibrillation. RESULTS. Heart rate variability did not differ between the two groups, and no consistent trends in heart rate variability were observed before ventricular fibrillation occurred. CONCLUSIONS. Although conventional heart rate variability is an independent long-term predictor of adverse outcome after myocardial infarction, its clinical utility as a short-term predictor of life-threatening arrhythmias remains to be elucidated.

  12. Usability of Three-dimensional Augmented Visual Cues Delivered by Smart Glasses on (Freezing of) Gait in Parkinson’s Disease

    PubMed Central

    Janssen, Sabine; Bolte, Benjamin; Nonnekes, Jorik; Bittner, Marian; Bloem, Bastiaan R.; Heida, Tjitske; Zhao, Yan; van Wezel, Richard J. A.

    2017-01-01

    External cueing is a potentially effective strategy to reduce freezing of gait (FOG) in persons with Parkinson’s disease (PD). Case reports suggest that three-dimensional (3D) cues might be more effective in reducing FOG than two-dimensional cues. We investigate the usability of 3D augmented reality visual cues delivered by smart glasses in comparison to conventional 3D transverse bars on the floor and auditory cueing via a metronome in reducing FOG and improving gait parameters. In laboratory experiments, 25 persons with PD and FOG performed walking tasks while wearing custom-made smart glasses under five conditions, at the end-of-dose. For two conditions, augmented visual cues (bars/staircase) were displayed via the smart glasses. The control conditions involved conventional 3D transverse bars on the floor, auditory cueing via a metronome, and no cueing. The number of FOG episodes and percentage of time spent on FOG were rated from video recordings. The stride length and its variability, cycle time and its variability, cadence, and speed were calculated from motion data collected with a motion capture suit equipped with 17 inertial measurement units. A total of 300 FOG episodes occurred in 19 out of 25 participants. There were no statistically significant differences in number of FOG episodes and percentage of time spent on FOG across the five conditions. The conventional bars increased stride length, cycle time, and stride length variability, while decreasing cadence and speed. No effects for the other conditions were found. Participants preferred the metronome most, and the augmented staircase least. They suggested to improve the comfort, esthetics, usability, field of view, and stability of the smart glasses on the head and to reduce their weight and size. In their current form, augmented visual cues delivered by smart glasses are not beneficial for persons with PD and FOG. This could be attributable to distraction, blockage of visual feedback, insufficient familiarization with the smart glasses, or display of the visual cues in the central rather than peripheral visual field. Future smart glasses are required to be more lightweight, comfortable, and user friendly to avoid distraction and blockage of sensory feedback, thus increasing usability. PMID:28659862

  13. Virtual reconstruction of the Early Pleistocene mandible ATD6-96 from Gran Dolina-TD6-2 (Sierra De Atapuerca, Spain).

    PubMed

    Bermúdez de Castro, José María; Martín-Francés, Laura; Modesto-Mata, Mario; Martínez de Pinillos, Marina; Martinón-Torres, María; García-Campos, Cecilia; Carretero, José Miguel

    2016-04-01

    In this report, we present a further study of the late Early Pleistocene ATD6-96 human mandible, recovered from the TD6-2 level of the Gran Dolina cave site (Sierra de Atapuerca, northern Spain) and attributed to Homo antecessor. ATD6-96 consists of a left half of a gracile mandible of an adult individual with the premolars and molars in place that is broken at the level of the lateral incisor-canine septum. The present analysis is based on a virtual reconstruction of the whole mandible by means of computed tomography (CT). We have reconstructed the symphysis using information from a modern human sample, as well as from a wide sample composed of several Homo specimens. This research has allowed us to record new variables with taxonomic and phylogenetic interest. We have estimated the length/width index of the alveolar arcade, as well as the percentage of the arcade length with regard to the total length. The latter confirms that ATD6-96 shares with all African and Asian Homo species a primitive structural pattern, as it was established in previous studies. In constrast, the length/width index of the alveolar arcade in the H. antecessor specimen is close to the mean values of Neandertals and the Atapuerca-Sima de los Huesos hominins. H. antecessor is derived regarding the shape of the mandibular alveolar arcade within the genus Homo and points to an early divergence from contemporaneous African populations. Our results also ratify the affinities of H. antecessor with Neanderthals, although the precise relationship with this lineage needs further research. © 2015 Wiley Periodicals, Inc.

  14. Is V-Y plasty necessary for penile lengthening? Girth enhancement and increased length solely through circumcision: description of a novel technique.

    PubMed

    Mertziotis, Nikos; Kozyrakis, Diomidis; Bogris, Elias

    2013-11-01

    Our objective is to describe a novel ligamentolysis approach using a subcoronal incision technique and to determine its safety and efficacy. During the last 7 years, 82 consecutive patients had penile augmentation surgery. Ligamentolysis, through a lower abdominal incision (V-Y plasty) in the first 35 males, was performed (Group A), followed by circumcision ligamentolysis in the next 47 males (Group B). The operation time, complications, and the preoperative and postoperative values of penile length and girth along with the self-esteem and relations questionnaire score as well as satisfaction score was calculated before and after the surgery, and a comparison was conducted between the groups. The mean age at presentation was 32 years (range: 18-56 years). Seventy-nine patients suffered from penile dysmorphophobia, and three patients had micropenises (length <7.5 cm). The mean surgical times were 150.7 and 125.2 min for Groups A and B, respectively (P=0.005). Postoperatively, four Group A patients and three Group B patients (11% versus 6%, respectively) experienced penile retraction (P=0.453). Hypertrophic scars were observed in 18 men (51%) in the former [corrected] group. In the circumcision group, no major wound complications were recorded. The length and girth improvements between the groups were similar. In terms of satisfaction and SEAR improvement, the resulting difference for both variables favored the circumcision group (P=0.007 and <0.001, respectively). With strict selection criteria, the circumcision ligamentolysis procedure compared to the V-Y plasty demonstrated improved results in terms of safety, operation time, retraction rate and cosmetic appearance without any compromise in the gained penile size.

  15. Determinants of sick-leave length: still limited to diagnosis elements.

    PubMed

    Lévy, Yvan; Denis, Angélique; Fassier, Jean-Baptiste; Kellou, Nadir; Schott, Anne-Marie; Letrilliart, Laurent

    2017-12-01

    Sickness certification implies that a health problem impairs ability to work. However, its assessment is seldom performed by physicians. Our objective was, therefore, to assess the specific influence of functional and environmental limitations on the length of sick-leave prescriptions. We conducted a cross-sectional study in French general teaching practices and recorded 353 initial sick-leave certifications. For each of them, the functional and environmental limitations were collected using the ATCIF questionnaire, derived from the International Classification of Functioning. Data analysis was based on a linear regression multivariate model. Among the functional limitations, "pain" was the main body function impairment (22% of impairments) and "mobility" the main activity limitation (48%). An environmental barrier was identified in 39% of sick-listed patients, mainly relating to "products and technology" (20%), which refers to workplace factors. The prescription was longer in cases of activity limitations relating to "mobility" and in cases of environmental barriers relating to "products and technology". The multivariate model explained 27% of the variability of sick-leave length through diagnosis elements and only 7% through functional and contextual elements. In sick-leave prescription, a functional and contextual approach, in addition to the traditional diagnosis-based approach, could better support patients' shared understanding and follow-up, and accountability towards health authorities. Implication for Rehabilitation Although sickness certification implies that a health problem impairs ability to work, decision on sick-leave length in general practice is primarily based on diagnosis. A more functional and contextual approach could better support patients' and other health professionals' shared understanding and follow-up, and accountability towards health authorities. Such evolution requires a change of paradigm in medical education, and the way of reasoning of healthcare professionals.

  16. [Treatment of juvenile scoliosis: Increasing the lengthening interval with the growing rod technique should not necessarily compromise thoracic growth].

    PubMed

    Pizones, J; Rodríguez-López, T; Zúñiga, L; Sánchez-Mariscal, F; Álvarez-González, P; Izquierdo, E

    2014-01-01

    Serial lengthening with growing rods is recommended every six months for the treatment of early onset scoliosis. The objective of this study was to evaluate the longitudinal growth of the thorax and control of the deformity in a series of patients with juvenile scoliosis when time intervals were increased between lengthenings. Retrospective study of eight patients. The following variables were measured: the Cobb angle, the apical vertebral translation, the coronal balance, thoracic T1-L1 length, thoracic T5-T12 kyphosis, the proximal junctional kyphosis (PJK) angle, and the lumbar lordosis. Complications were recorded. Five idiopathic and three syndromic scoliosis cases (mean age 9.4 ± 1.5 years) were evaluated. The initial surgery was followed by with an average of two distractions per patient. The mean time between distractions was 15.7 months. The final coronal main curve correction was 58%. Apical translation and coronal balance were improved and maintained after the surgeries. The thoracic (T1-L1) preoperative length was 20.8 cm, the postoperative length was 24.4 cm, and the final length was 26 cm. At the end of follow-up, the average growth of the thorax was 5.2 cm. The preoperative (T5-T12) kyphosis was 33.5°, and final 32.1°. The change in the PJK angle was 2.5° at the end of follow-up. Most complications were related to instrumentation. Two superficial wound infections were encountered. For less severe juvenile scoliosis patients treated with growing rods, spacing out lengthenings over more than a year can decrease the number of surgeries, while still controlling the deformity and allowing longitudinal thoracic growth. Copyright © 2014 SECOT. Published by Elsevier Espana. All rights reserved.

  17. Understanding high magnitude flood risk: evidence from the past

    NASA Astrophysics Data System (ADS)

    MacDonald, N.

    2009-04-01

    The average length of gauged river flow records in the UK is ~25 years, which presents a problem in determining flood risk for high-magnitude flood events. Severe floods have been recorded in many UK catchments during the past 10 years, increasing the uncertainty in conventional flood risk estimates based on river flow records. Current uncertainty in flood risk has implications for society (insurance costs), individuals (personal vulnerability) and water resource managers (flood/drought risk). An alternative approach is required which can improve current understanding of the flood frequency/magnitude relationship. Historical documentary accounts are now recognised as a valuable resource when considering the flood frequency/magnitude relationship, but little consideration has been given to the temporal and spatial distribution of these records. Building on previous research based on British rivers (urban centre): Ouse (York), Trent (Nottingham), Tay (Perth), Severn (Shrewsbury), Dee (Chester), Great Ouse (Cambridge), Sussex Ouse (Lewes), Thames (Oxford), Tweed (Kelso) and Tyne (Hexham), this work considers the spatial and temporal distribution of historical flooding. The selected sites provide a network covering many of the largest river catchments in Britain, based on urban centres with long detailed documentary flood histories. The chronologies offer an opportunity to assess long-term patterns of flooding, indirectly determining periods of climatic variability and potentially increased geomorphic activity. This research represents the first coherent large scale analysis undertaken of historical multi-catchment flood chronologies, providing an unparalleled network of sites, permitting analysis of the spatial and temporal distribution of historical flood patterns on a national scale.

  18. [Reporting echocardiography exams with the G8-Cardio ANMCO software].

    PubMed

    Badano, L P; Marchesini, A; Pizzuti, A; Mantero, A; Cianflone, D; Neri, E; Caira, P; Tubaro, M

    2001-03-01

    The availability of a common computerized program for echocardiographic study archiving and reporting at national and/or international level could make it possible to standardize the echo reports of different echocardiographic laboratories, and to use the wealth of data thus obtainable with echocardiography, and to exploit its capillary territorial distribution, with the aim of collecting echocardiographic data in a standard format for epidemiological, scientific and administrative purposes. To develop such a software, an ad hoc joint National Association of Hospital Cardiologists and Italian Society of Echocardiography task force worked in conjunction with the Italian Branch of Agilent Technologies to standardize the phraseology of accepted echocardiographic terms and of the quantitative parameters derived from transthoracic and transesophageal echocardiographic examination at rest as well as during exercise and pharmacological stress, and to develop an ad hoc software. This echocardiographic study archiving and reporting program is part of the whole G8-Cardio ANMCO software developed to computerize the whole cardiological chart. The software has been developed by Agilent Technologies to provide a fast, easy-access and easy to use report generator for the non-computer specialist using DBMS Oracle 7.3 database and Power Builder 5.0 to develop a user-friendly interface. The number of qualitative and quantitative variables contained in the program is 733 for echocardiography at rest, while it depends on the stressor and on the length of the examination for the stress echo (dipyridamole 214-384, dobutamine 236-406, exercise 198-392). The program was tested and refined in our laboratory between November 1999 and May 2000. During this time period, 291 resting and 56 stress echocardiographic studies were reported and recorded in a database. On average, each resting echocardiographic study lasting 10 +/- 4 (range 5-17) min was recorded using 50 +/- 11 (range 33-67) variables and 41,566 bytes of hard-disk memory space. Stress echocardiographic studies, each lasting 7 +/- 5 (range 5-21) min, were recorded using 143 +/- 74 (range 38-194) variables and 38,531 bytes of hard-disk memory space. To our knowledge this software represents the first experience of a common computerized program for echo archiving and reporting carried out at national level.

  19. Estimating flood magnitude and frequency at gaged and ungaged sites on streams in Alaska and conterminous basins in Canada, based on data through water year 2012

    USGS Publications Warehouse

    Curran, Janet H.; Barth, Nancy A.; Veilleux, Andrea G.; Ourso, Robert T.

    2016-03-16

    Estimates of the magnitude and frequency of floods are needed across Alaska for engineering design of transportation and water-conveyance structures, flood-insurance studies, flood-plain management, and other water-resource purposes. This report updates methods for estimating flood magnitude and frequency in Alaska and conterminous basins in Canada. Annual peak-flow data through water year 2012 were compiled from 387 streamgages on unregulated streams with at least 10 years of record. Flood-frequency estimates were computed for each streamgage using the Expected Moments Algorithm to fit a Pearson Type III distribution to the logarithms of annual peak flows. A multiple Grubbs-Beck test was used to identify potentially influential low floods in the time series of peak flows for censoring in the flood frequency analysis.For two new regional skew areas, flood-frequency estimates using station skew were computed for stations with at least 25 years of record for use in a Bayesian least-squares regression analysis to determine a regional skew value. The consideration of basin characteristics as explanatory variables for regional skew resulted in improvements in precision too small to warrant the additional model complexity, and a constant model was adopted. Regional Skew Area 1 in eastern-central Alaska had a regional skew of 0.54 and an average variance of prediction of 0.45, corresponding to an effective record length of 22 years. Regional Skew Area 2, encompassing coastal areas bordering the Gulf of Alaska, had a regional skew of 0.18 and an average variance of prediction of 0.12, corresponding to an effective record length of 59 years. Station flood-frequency estimates for study sites in regional skew areas were then recomputed using a weighted skew incorporating the station skew and regional skew. In a new regional skew exclusion area outside the regional skew areas, the density of long-record streamgages was too sparse for regional analysis and station skew was used for all estimates. Final station flood frequency estimates for all study streamgages are presented for the 50-, 20-, 10-, 4-, 2-, 1-, 0.5-, and 0.2-percent annual exceedance probabilities.Regional multiple-regression analysis was used to produce equations for estimating flood frequency statistics from explanatory basin characteristics. Basin characteristics, including physical and climatic variables, were updated for all study streamgages using a geographical information system and geospatial source data. Screening for similar-sized nested basins eliminated hydrologically redundant sites, and screening for eligibility for analysis of explanatory variables eliminated regulated peaks, outburst peaks, and sites with indeterminate basin characteristics. An ordinary least‑squares regression used flood-frequency statistics and basin characteristics for 341 streamgages (284 in Alaska and 57 in Canada) to determine the most suitable combination of basin characteristics for a flood-frequency regression model and to explore regional grouping of streamgages for explaining variability in flood-frequency statistics across the study area. The most suitable model for explaining flood frequency used drainage area and mean annual precipitation as explanatory variables for the entire study area as a region. Final regression equations for estimating the 50-, 20-, 10-, 4-, 2-, 1-, 0.5-, and 0.2-percent annual exceedance probability discharge in Alaska and conterminous basins in Canada were developed using a generalized least-squares regression. The average standard error of prediction for the regression equations for the various annual exceedance probabilities ranged from 69 to 82 percent, and the pseudo-coefficient of determination (pseudo-R2) ranged from 85 to 91 percent.The regional regression equations from this study were incorporated into the U.S. Geological Survey StreamStats program for a limited area of the State—the Cook Inlet Basin. StreamStats is a national web-based geographic information system application that facilitates retrieval of streamflow statistics and associated information. StreamStats retrieves published data for gaged sites and, for user-selected ungaged sites, delineates drainage areas from topographic and hydrographic data, computes basin characteristics, and computes flood frequency estimates using the regional regression equations.

  20. Does Day Length Affect Winter Bird Distribution? Testing the Role of an Elusive Variable

    PubMed Central

    Carrascal, Luis M.; Santos, Tomás; Tellería, José L.

    2012-01-01

    Differences in day length may act as a critical factor in bird biology by introducing time constraints in energy acquisition during winter. Thus, differences in day length might operate as a main determinant of bird abundance along latitudinal gradients. This work examines the influence of day length on the abundance of wintering crested tits (Lophophanes cristatus) in 26 localities of Spanish juniper (Juniperus thurifera) dwarf woodlands (average height of 5 m) located along a latitudinal gradient in the Spanish highlands, while controlling for the influence of food availability, minimum night temperature, habitat structure and landscape characteristics. Top regression models in the AIC framework explained 56% of variance in bird numbers. All models incorporated day length as the variable with the highest magnitude effect. Food availability also played an important role, although only the crop of ripe juniper fruits, but not arthropods, positively affected crested tit abundance. Differences in vegetation structure across localities had also a strong positive effect (average tree height and juniper tree density). Geographical variation in night temperature had no influence on crested tit distribution, despite the low winter temperatures reached in these dwarf forests. This paper demonstrates for the first time that winter bird abundance increases with day length after controlling for the effect of other environmental variables. Winter average difference in day length was only 10.5 minutes per day along the 1°47′ latitudinal interval (190 km) included in this study. This amount of time, which reaches 13.5 h accumulated throughout the winter season, appears to be large enough to affect the long-term energy budget of small passerines during winter and to shape the distribution of winter bird abundance under restrictive environmental conditions. PMID:22393442

  1. Laparoscopic versus open repair of perforated peptic ulcer: A retrospective cohort study.

    PubMed

    Smith, Rohan Stuart; Sundaramurthy, Senthilkumar Rajavel; Croagh, Daniel

    2018-05-27

    Perforated peptic ulcer disease (PPU) is a condition subject to wide geographical variations in incidence. It remains a significant cause of morbidity and mortality, even in the era of Helicobacter pylori eradication and proton-pump inhibitor therapy. There is no clear consensus on whether laparoscopic or open approaches are superior, and with most studies in this area originating from Europe and Asia, Australian data addressing this issue are lacking. This retrospective cohort study included all patients who underwent surgery for PPU within a hospital network in Australia. Baseline variables and primary outcomes, including length of hospital stay, chest and abdominal complications, and mortality, were recorded. Secondary outcomes, including reasons for conversion, were also considered. In total, 109 patients underwent operations for PPU between January 2011 and December 2015. There were no significant differences with regard to baseline comorbidities. There were no statistically significant differences in terms of median length of hospital stay or rates of chest and abdominal complications, but the operative time was 28.5 min longer (P = <0.001) in the laparoscopic group than in the open group. Open operations were faster to perform than laparoscopic operations for repair of PPU. Despite increased experience treating many surgical diseases laparoscopically, this study did not find it to be superior in terms of length of hospital stay or complication rates. © 2018 Japan Society for Endoscopic Surgery, Asia Endosurgery Task Force and John Wiley & Sons Australia, Ltd.

  2. Pressure ulcer incidence and Braden subscales: Retrospective cohort analysis in general wards of a Portuguese hospital.

    PubMed

    Sardo, Pedro Miguel Garcez; Guedes, Jenifer Adriana Domingues; Alvarelhão, José Joaquim Marques; Machado, Paulo Alexandre Puga; Melo, Elsa Maria Oliveira Pinheiro

    2018-05-01

    To study the influence of Braden subscales scores (at the first pressure ulcer risk assessment) on pressure ulcer incidence using a univariate and a multivariate time to event analysis. Retrospective cohort analysis of electronic health record database from adult patients admitted without pressure ulcer(s) to medical and surgical wards of a Portuguese hospital during 2012. The hazard ratio of developing a pressure ulcer during the length of inpatient stay was calculated by univariate Cox regression for each variable of interest and by multivariate Cox regression for the Braden subscales that were statistically significant. This study included a sample of 6552 participants. During the length of stay, 153 participants developed (at least) one pressure ulcer, giving a pressure ulcer incidence of 2.3%. The univariate time to event analysis showed that all Braden subscales, except "nutrition", were associated with the development of pressure ulcer. By multivariate analysis the scores for "mobility" and "activity" were independently predictive of the development of pressure ulcer(s) for all participants. (Im)"mobility" (the lack of ability to change and control body position) and (in)"activity" (the limited degree of physical activity) were the major risk factors assessed by Braden Scale for pressure ulcer development during the length of inpatient stay. Thus, the greatest efforts in managing pressure ulcer risk should be on "mobility" and "activity", independently of the total Braden Scale score. Copyright © 2018 Tissue Viability Society. Published by Elsevier Ltd. All rights reserved.

  3. Climatic interpretation of the length fluctuations of Glaciar Frías, North Patagonia, Argentina

    NASA Astrophysics Data System (ADS)

    Leclercq, P. W.; Pitte, P.; Giesen, R. H.; Masiokas, M. H.; Oerlemans, J.

    2011-10-01

    We explore the climatic information contained in the record of length fluctuations of Glaciar Frías, in the North Patagonian Andes of Argentina. This record is one of the longest and most detailed glacier records in southern South America, starting in 1639. In order to interpret the length variations of Glaciar Frías since the maximum Little Ice Age extent in 1639, we use a combination of a simplified surface energy-balance model to calculate the glacier mass balance, and a flow-line model to account for the dynamical response of the glacier to changes in the climatic forcing. The overall retreat of the glacier observed over 1639-2009 is best explained by an annual mean temperature increase of 1.16 °C or a decrease in annual precipitation of 34%, most of which would have occurred during the 20th century. The glacier model is also forced with independent proxy-based reconstructions of precipitation and temperature, based on tree rings and a composition of documentary evidence, tree rings, sediments, corals, and ice cores. The uncertainties in the presently available proxy reconstructions are rather large, leading to a wide range in the modelled glacier length. Most of the observations lie within this range. However, in these reconstructions, the mid-17th century is too cold and the early 19th century ca. 0.7 °C too warm to explain the observed glacier lengths.

  4. Stigma predicts residential treatment length for substance use disorder

    PubMed Central

    Luoma, Jason B.; Kulesza, Magdalena; Hayes, Steven C.; Kohlenberg, Barbara; Larimer, Mary

    2016-01-01

    Background Stigma has been suggested as a possible contributor to the high rates of treatment attrition in substance-dependent individuals, but no published empirical studies have examined this association. Objectives The present paper assessed the relationship between baseline stigma variables and length of treatment stay in a sample of patients in a residential addictions treatment unit. Methods The relationship between baseline stigma variables (self-stigma, enacted stigma, and shame) and length of stay for participants (n = 103) in a residential addictions treatment unit was examined. Results Higher self-stigma predicted longer stay in residential addictions treatment, even after controlling for age, marital status, race, overall mental health, social support, enacted stigma, and internalized shame. However, other stigma variables (i.e. internalized shame, stigma-related rejection) did not reliably predict length of treatment stay. Conclusion These results are consistent with other findings suggesting that people with higher self-stigma may have a lowered sense of self-efficacy and heightened fear of being stigmatized and therefore retreat into more protected settings such as residential treatment, potentially resulting in higher treatment costs. Specialized clinical interventions may be necessary to help participants cope with reduced self-efficacy and fear of being stigmatized. PMID:24766087

  5. Investigating the Effect of Recruitment Variability on Length-Based Recruitment Indices for Antarctic Krill Using an Individual-Based Population Dynamics Model

    PubMed Central

    Thanassekos, Stéphane; Cox, Martin J.; Reid, Keith

    2014-01-01

    Antarctic krill (Euphausia superba; herein krill) is monitored as part of an on-going fisheries observer program that collects length-frequency data. A krill feedback management programme is currently being developed, and as part of this development, the utility of data-derived indices describing population level processes is being assessed. To date, however, little work has been carried out on the selection of optimum recruitment indices and it has not been possible to assess the performance of length-based recruitment indices across a range of recruitment variability. Neither has there been an assessment of uncertainty in the relationship between an index and the actual level of recruitment. Thus, until now, it has not been possible to take into account recruitment index uncertainty in krill stock management or when investigating relationships between recruitment and environmental drivers. Using length-frequency samples from a simulated population – where recruitment is known – the performance of six potential length-based recruitment indices is assessed, by exploring the index-to-recruitment relationship under increasing levels of recruitment variability (from ±10% to ±100% around a mean annual recruitment). The annual minimum of the proportion of individuals smaller than 40 mm (F40 min, %) was selected because it had the most robust index-to-recruitment relationship across differing levels of recruitment variability. The relationship was curvilinear and best described by a power law. Model uncertainty was described using the 95% prediction intervals, which were used to calculate coverage probabilities and assess model performance. Despite being the optimum recruitment index, the performance of F40 min degraded under high (>50%) recruitment variability. Due to the persistence of cohorts in the population over several years, the inclusion of F40 min values from preceding years in the relationship used to estimate recruitment in a given year improved its accuracy (mean bias reduction of 8.3% when including three F40 min values under a recruitment variability of 60%). PMID:25470296

  6. Smoothing of millennial scale climate variability in European Loess (and other records)

    NASA Astrophysics Data System (ADS)

    Zeeden, Christian; Obreht, Igor; Hambach, Ulrich; Veres, Daniel; Marković, Slobodan B.; Lehmkuhl, Frank

    2017-04-01

    Millennial scale climate variability is seen in various records of the northern hemisphere in the last glacial cycle, and their expression represents a correlation tool beyond the resolution of e.g. luminescence dating. Highest (correlative) dating accuracy is a prerequisite of comparing different geoarchives, especially when related to archaeological findings. Here we attempt to constrain the timing of loess geoarchives representing the environmental context of early humans in south-eastern Europe, and discuss the challenge of dealing with smoothed records. In this contribution, we present rock magnetic and grain size data from the Rasova loess record in the Lower Danube basin (Romania), showing millennial scale climate variability. Additionally, we summarize similar data from the Lower and Middle Danube Basins. A comparison of these loess data and reference records from Greenland ice cores and the Mediterranean-Black Sea region indicates a rather unusual expression of millennial scale climate variability recorded in loess. To explain the observed patterns, we experiment with low-pass filters of reference records to simulate a signal smoothing by natural processes such as e.g. bioturbation and pervasive diagenesis. Low-pass filters avoid high frequency oscillations and focus on the longer period (lower frequency) variability, here using cut-off periods from 1-15 kyr. In our opinion low-pass filters represent simple models for the expression of millennial scale climate variability in low sedimentation environments, and in sediments where signals are smoothed by e.g. bioturbation and/or diagenesis. Using different low-pass filter thresholds allows us to (a) explain observed patterns and their relation to millennial scale climate variability, (b) propose these filtered/smoothed signals as correlation targets for records lacking millennial scale recording, but showing smoothed climate variability on supra-millennial scales, and (c) determine which time resolution specific (loess) records can reproduce. Comparing smoothed records to reference data may be a step forward especially for last glacial stratigraphies, where millennial scale patterns are certainly present but not directly recorded in some geoarchives. Interestingly, smoothed datasets from Greenland and the Black Sea-Mediterranean region are most similar in the last ca. 15 ka and again from ca. 30-50 ka. During the cold phase from ca. 30-15 ka records show dissimilarities, challenging robust correlative time scales in this age range. A potential explanation may be related to the expansion of Northern European and Alpine ice sheets influencing atmospheric systems in the North Atlantic and Eurasian regions and thus leading to regionally and temporally differentiated climatic responses.

  7. Kinematic predictors of star excursion balance test performance in individuals with chronic ankle instability.

    PubMed

    Hoch, Matthew C; Gaven, Stacey L; Weinhandl, Joshua T

    2016-06-01

    The Star Excursion Balance Test has identified dynamic postural control deficits in individuals with chronic ankle instability. While kinematic predictors of Star Excursion Balance Test performance have been evaluated in healthy individuals, this has not been thoroughly examined in individuals with chronic ankle instability. Fifteen individuals with chronic ankle instability completed the anterior reach direction of the Star Excursion Balance Test and weight-bearing dorsiflexion assessments. Maximum reach distances on the Star Excursion Balance Test were measured in cm and normalized to leg length. Three-dimensional trunk, hip, knee, and ankle motion of the stance limb were recorded during each anterior reach trial using a motion capture system. Sagittal, frontal, and transverse plane displacement observed from trial initiation to the point of maximum reach was calculated for each joint or segment and averaged for analysis. Pearson product-moment correlations were performed to examine the relationships between kinematic variables, maximal reach, and weight-bearing dorsiflexion. A backward multiple linear regression model was developed with maximal reach as the criterion variable and kinematic variables as predictors. Frontal plane displacement of the trunk, hip, and ankle and sagittal plane knee displacement were entered into the analysis. The final model (p=0.004) included all three frontal plane variables and explained 81% of the variance in maximal reach. Maximal reach distance and several kinematic variables were significantly related to weight-bearing dorsiflexion. Individuals with chronic ankle instability who demonstrated greater lateral trunk displacement toward the stance limb, hip adduction, and ankle eversion achieved greater maximal reach. Copyright © 2016. Published by Elsevier Ltd.

  8. Predicting regime shifts in flow of the Colorado River

    USGS Publications Warehouse

    Gangopadhyay, Subhrendu; McCabe, Gregory J.

    2010-01-01

    The effects of continued global warming on water resources are a concern for water managers and stake holders. In the western United States, where the combined climatic demand and consumptive use of water is equal to or greater than the natural supply of water for some locations, there is growing concern regarding the sustainability of future water supplies. In addition to the adverse effects of warming on water supply, another issue for water managers is accounting for, and managing, the effects of natural climatic variability, particularly persistently dry and wet periods. Analyses of paleo-reconstructions of Upper Colorado River basin (UCRB) flow demonstrate that severe sustained droughts, and persistent pluvial periods, are a recurring characteristic of hydroclimate in the Colorado River basin. Shifts between persistently dry and wet regimes (e.g., decadal to multi-decadal variability (D2M)) have important implications for water supply and water management. In this study paleo-reconstructions of UCRB flow are used to compute the risks of shifts between persistently wet and dry regimes given the length of time in a specific regime. Results indicate that low frequency variability of hydro-climatic conditions and the statistics that describe this low frequency variability can be useful to water managers by providing information about the risk of shifting from one hydrologic regime to another. To manage water resources in the future water managers will have to understand the joint hydrologic effects of natural climate variability and global warming. These joint effects may produce future hydrologic conditions that are unprecedented in both the instrumental and paleoclimatic records.

  9. Quantifying center of pressure variability in chondrodystrophoid dogs.

    PubMed

    Blau, S R; Davis, L M; Gorney, A M; Dohse, C S; Williams, K D; Lim, J-H; Pfitzner, W G; Laber, E; Sawicki, G S; Olby, N J

    2017-08-01

    The center of pressure (COP) position reflects a combination of proprioceptive, motor and mechanical function. As such, it can be used to quantify and characterize neurologic dysfunction. The aim of this study was to describe and quantify the movement of COP and its variability in healthy chondrodystrophoid dogs while walking to provide a baseline for comparison to dogs with spinal cord injury due to acute intervertebral disc herniations. Fifteen healthy adult chondrodystrophoid dogs were walked on an instrumented treadmill that recorded the location of each dog's COP as it walked. Center of pressure (COP) was referenced from an anatomical marker on the dogs' back. The root mean squared (RMS) values of changes in COP location in the sagittal (y) and horizontal (x) directions were calculated to determine the range of COP variability. Three dogs would not walk on the treadmill. One dog was too small to collect interpretable data. From the remaining 11 dogs, 206 trials were analyzed. Mean RMS for change in COPx per trial was 0.0138 (standard deviation, SD 0.0047) and for COPy was 0.0185 (SD 0.0071). Walking speed but not limb length had a significant effect on COP RMS. Repeat measurements in six dogs had high test retest consistency in the x and fair consistency in the y direction. In conclusion, COP variability can be measured consistently in dogs, and a range of COP variability for normal chondrodystrophoid dogs has been determined to provide a baseline for future studies on dogs with spinal cord injury. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Continuously variable focal length lens

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adams, Bernhard W; Chollet, Matthieu C

    2013-12-17

    A material preferably in crystal form having a low atomic number such as beryllium (Z=4) provides for the focusing of x-rays in a continuously variable manner. The material is provided with plural spaced curvilinear, optically matched slots and/or recesses through which an x-ray beam is directed. The focal length of the material may be decreased or increased by increasing or decreasing, respectively, the number of slots (or recesses) through which the x-ray beam is directed, while fine tuning of the focal length is accomplished by rotation of the material so as to change the path length of the x-ray beammore » through the aligned cylindrical slows. X-ray analysis of a fixed point in a solid material may be performed by scanning the energy of the x-ray beam while rotating the material to maintain the beam's focal point at a fixed point in the specimen undergoing analysis.« less

  11. Evaluation of Variable-Depth Liner Configurations for Increased Broadband Noise Reduction

    NASA Technical Reports Server (NTRS)

    Jones, M. G.; Watson, W. R.; Nark, D. M.; Howerton, B. M.

    2015-01-01

    This paper explores the effects of variable-depth geometry on the amount of noise reduction that can be achieved with acoustic liners. Results for two variable-depth liners tested in the NASA Langley Grazing Flow Impedance Tube demonstrate significant broadband noise reduction. An impedance prediction model is combined with two propagation codes to predict corresponding sound pressure level profiles over the length of the Grazing Flow Impedance Tube. The comparison of measured and predicted sound pressure level profiles is sufficiently favorable to support use of these tools for investigation of a number of proposed variable-depth liner configurations. Predicted sound pressure level profiles for these proposed configurations reveal a number of interesting features. Liner orientation clearly affects the sound pressure level profile over the length of the liner, but the effect on the total attenuation is less pronounced. The axial extent of attenuation at an individual frequency continues well beyond the location where the liner depth is optimally tuned to the quarter-wavelength of that frequency. The sound pressure level profile is significantly affected by the way in which variable-depth segments are distributed over the length of the liner. Given the broadband noise reduction capability for these liner configurations, further development of impedance prediction models and propagation codes specifically tuned for this application is warranted.

  12. "The caterpillar": a novel reading passage for assessment of motor speech disorders.

    PubMed

    Patel, Rupal; Connaghan, Kathryn; Franco, Diana; Edsall, Erika; Forgit, Dory; Olsen, Laura; Ramage, Lianna; Tyler, Emily; Russell, Scott

    2013-02-01

    A review of the salient characteristics of motor speech disorders and common assessment protocols revealed the need for a novel reading passage tailored specifically to differentiate between and among the dysarthrias (DYSs) and apraxia of speech (AOS). "The Caterpillar" passage was designed to provide a contemporary, easily read, contextual speech sample with specific tasks (e.g., prosodic contrasts, words of increasing length and complexity) targeted to inform the assessment of motor speech disorders. Twenty-two adults, 15 with DYS or AOS and 7 healthy controls (HC), were recorded reading "The Caterpillar" passage to demonstrate its utility in examining motor speech performance. Analysis of performance across a subset of segmental and prosodic variables illustrated that "The Caterpillar" passage showed promise for extracting individual profiles of impairment that could augment current assessment protocols and inform treatment planning in motor speech disorders.

  13. Differences in duration of eye fixation for conditions in a numerical stroop-effect experiment.

    PubMed

    Crespo, Antonio; Cabestrero, Raúl; Quirós, Pilar

    2009-02-01

    Durations of eye fixation were recorded for a numerical Stroop effect experiment. Participants (6 men, 19 women; M age=22 yr.) reported the number of characters present in sequences of variable length (2 to 5 characters) while attempting to ignore the identity of the character. Three conditions were included: congruent (the number of characters and the numeral were matched, e.g., responding "two" to 22), incongruent (the number of characters and the numeral were mismatched, e.g., responding "two" to 55), and control (baseline of stimuli made up of "X"s, e.g., responding "two" to XX). Comparisons among the three conditions produced the longest response times and average durations of fixation for the incongruent condition. The shortest response times and average durations of fixation were obtained for the congruent condition.

  14. Long-term variability of global statistical properties of epileptic brain networks

    NASA Astrophysics Data System (ADS)

    Kuhnert, Marie-Therese; Elger, Christian E.; Lehnertz, Klaus

    2010-12-01

    We investigate the influence of various pathophysiologic and physiologic processes on global statistical properties of epileptic brain networks. We construct binary functional networks from long-term, multichannel electroencephalographic data recorded from 13 epilepsy patients, and the average shortest path length and the clustering coefficient serve as global statistical network characteristics. For time-resolved estimates of these characteristics we observe large fluctuations over time, however, with some periodic temporal structure. These fluctuations can—to a large extent—be attributed to daily rhythms while relevant aspects of the epileptic process contribute only marginally. Particularly, we could not observe clear cut changes in network states that can be regarded as predictive of an impending seizure. Our findings are of particular relevance for studies aiming at an improved understanding of the epileptic process with graph-theoretical approaches.

  15. ETHOWATCHER: validation of a tool for behavioral and video-tracking analysis in laboratory animals.

    PubMed

    Crispim Junior, Carlos Fernando; Pederiva, Cesar Nonato; Bose, Ricardo Chessini; Garcia, Vitor Augusto; Lino-de-Oliveira, Cilene; Marino-Neto, José

    2012-02-01

    We present a software (ETHOWATCHER(®)) developed to support ethography, object tracking and extraction of kinematic variables from digital video files of laboratory animals. The tracking module allows controlled segmentation of the target from the background, extracting image attributes used to calculate the distance traveled, orientation, length, area and a path graph of the experimental animal. The ethography module allows recording of catalog-based behaviors from environment or from video files continuously or frame-by-frame. The output reports duration, frequency and latency of each behavior and the sequence of events in a time-segmented format, set by the user. Validation tests were conducted on kinematic measurements and on the detection of known behavioral effects of drugs. This software is freely available at www.ethowatcher.ufsc.br. Copyright © 2011 Elsevier Ltd. All rights reserved.

  16. Correlation Between Fracture Network Properties and Stress Variability in Geological Media

    NASA Astrophysics Data System (ADS)

    Lei, Qinghua; Gao, Ke

    2018-05-01

    We quantitatively investigate the stress variability in fractured geological media under tectonic stresses. The fracture systems studied include synthetic fracture networks following power law length scaling and natural fracture patterns based on outcrop mapping. The stress field is derived from a finite-discrete element model, and its variability is analyzed using a set of mathematical formulations that honor the tensorial nature of stress data. We show that local stress perturbation, quantified by the Euclidean distance of a local stress tensor to the mean stress tensor, has a positive, linear correlation with local fracture intensity, defined as the total fracture length per unit area within a local sampling window. We also evaluate the stress dispersion of the entire stress field using the effective variance, that is, a scalar-valued measure of the overall stress variability. The results show that a well-connected fracture system under a critically stressed state exhibits strong local and global stress variabilities.

  17. Coral Records of 20th Century Central Tropical Pacific SST and Salinity: Signatures of Natural and Anthropogenic Climate Change

    NASA Astrophysics Data System (ADS)

    Nurhati, I. S.; Cobb, K.; Di Lorenzo, E.

    2011-12-01

    Accurate forecasts of regional climate changes in many regions of the world largely depend on quantifying anthropogenic trends in tropical Pacific climate against its rich background of interannual to decadal-scale climate variability. However, the strong natural climate variability combined with limited instrumental climate datasets have obscured potential anthropogenic climate signals in the region. Here, we present coral-based sea-surface temperature (SST) and salinity proxy records over the 20th century (1898-1998) from the central tropical Pacific - a region sensitive to El Niño-Southern Oscillation (ENSO) whose variability strongly impacts the global climate. The SST and salinity proxy records are reconstructed via coral Sr/Ca and the oxygen isotopic composition of seawater (δ18Osw), respectively. On interannual (2-7yr) timescales, the SST proxy record tracks both eastern- and central-Pacific flavors of ENSO variability (R=0.65 and R=0.67, respectively). Interannual-scale salinity variability in our coral record highlights profound differences in precipitation and ocean advections during the two flavors of ENSO. On decadal (8yr-lowpassed) timescales, the central tropical Pacific SST and salinity proxy records are controlled by different sets of dynamics linked to the leading climate modes of North Pacific climate variability. Decadal-scale central tropical Pacific SST is highly correlated to the recently discovered North Pacific Gyre Oscillation (NPGO; R=-0.85), reflecting strong dynamical links between the central Pacific warming mode and extratropical decadal climate variability. Whereas decadal-scale salinity variations in the central tropical Pacific are significantly correlated with the Pacific Decadal Oscillation (PDO; R=0.54), providing a better understanding on low-frequency salinity variability in the region. Having characterized natural climate variability in this region, the coral record shows a +0.5°C warming trend throughout the last century. However, the most prominent feature of the new coral records is an unprecedented freshening trend since the mid-20th century, in line with global climate models (GCMs) projections of enhanced hydrological patterns (wet areas are getting wetter and vice versa) under greenhouse forcing. Taken together, the coral records provide key constraints on tropical Pacific climate trends that may improve regional climate projections in areas affected by tropical Pacific climate variability.
    Central Tropical Pacific SST and Salinity Proxy Records

  18. Current Trends in Racial, Ethnic, and Healthcare Disparities Associated with Pediatric Cardiac Surgery Outcomes

    PubMed Central

    Peterson, Jennifer K.; Chen, Yanjun; Nguyen, Danh V.; Setty, Shaun P.

    2017-01-01

    Objective Despite overall improvements in congenital heart disease outcomes, racial and ethnic disparities have continued. The purpose of this study is to examine the effect of race and ethnicity, as well as other risk factors on congenital heart surgery length of stay and in-hospital mortality. Design From the 2012 Healthcare Cost and Utilization Project Kids Inpatient Database (KID), we identified 13,130 records with Risk Adjustment in Congenital Heart Surgery complexity score-eligible procedures. Multivariate logistic and linear regression modeling with survey weights, stratification and clustering was used to examine the relationships between predictor variables and length of stay as well as in-hospital mortality. Results No significant mortality differences were found among all race and ethnicity groups across each age group. Black neonates and black infants had a longer length of stay (neonatal Estimate = 8.73 days, p = .0034; infant Estimate 1.10 days, p = 0.0253), relative to whites. Government-sponsored insurance was associated with increased odds of neonatal mortality (odds ratio = 1.51, p = .0055), increased length of stay in neonates (Estimate = 4.26 days, p = .0009) and infants (Estimate = 1.52 days, p = .0181), relative to private insurance. Government-sponsored insurance was associated with increased number of chronic conditions, which were also associated with increased LOS (estimate 8.39 days, p < 0.001 in neonates; estimate 3.60 days, p < 0.001 in infants; estimate 1.87 days, p < 0.001 children). Conclusions Racial/ethnic disparities in congenital heart surgical outcomes may be changing compared to previous studies using the KID database. Increased length of stay in children with government-sponsored insurance may reflect expansion of individual states government-sponsored insurance eligibility criteria for children with complex chronic medical conditions. These findings warrant cautious optimism regarding racial and ethnic disparities in congenital heart surgery outcomes. PMID:28544396

  19. Open access intrapartum CTG database.

    PubMed

    Chudáček, Václav; Spilka, Jiří; Burša, Miroslav; Janků, Petr; Hruban, Lukáš; Huptych, Michal; Lhotská, Lenka

    2014-01-13

    Cardiotocography (CTG) is a monitoring of fetal heart rate and uterine contractions. Since 1960 it is routinely used by obstetricians to assess fetal well-being. Many attempts to introduce methods of automatic signal processing and evaluation have appeared during the last 20 years, however still no significant progress similar to that in the domain of adult heart rate variability, where open access databases are available (e.g. MIT-BIH), is visible. Based on a thorough review of the relevant publications, presented in this paper, the shortcomings of the current state are obvious. A lack of common ground for clinicians and technicians in the field hinders clinically usable progress. Our open access database of digital intrapartum cardiotocographic recordings aims to change that. The intrapartum CTG database consists in total of 552 intrapartum recordings, which were acquired between April 2010 and August 2012 at the obstetrics ward of the University Hospital in Brno, Czech Republic. All recordings were stored in electronic form in the OB TraceVue®;system. The recordings were selected from 9164 intrapartum recordings with clinical as well as technical considerations in mind. All recordings are at most 90 minutes long and start a maximum of 90 minutes before delivery. The time relation of CTG to delivery is known as well as the length of the second stage of labor which does not exceed 30 minutes. The majority of recordings (all but 46 cesarean sections) is - on purpose - from vaginal deliveries. All recordings have available biochemical markers as well as some more general clinical features. Full description of the database and reasoning behind selection of the parameters is presented in the paper. A new open-access CTG database is introduced which should give the research community common ground for comparison of results on reasonably large database. We anticipate that after reading the paper, the reader will understand the context of the field from clinical and technical perspectives which will enable him/her to use the database and also understand its limitations.

  20. The Aristotle Comprehensive Complexity score predicts mortality and morbidity after congenital heart surgery.

    PubMed

    Bojan, Mirela; Gerelli, Sébastien; Gioanni, Simone; Pouard, Philippe; Vouhé, Pascal

    2011-04-01

    The Aristotle Comprehensive Complexity (ACC) score has been proposed for complexity adjustment in the analysis of outcome after congenital heart surgery. The score is the sum of the Aristotle Basic Complexity score, largely used but poorly related to mortality and morbidity, and of the Comprehensive Complexity items accounting for comorbidities and procedure-specific and anatomic variability. This study aims to demonstrate the ability of the ACC score to predict 30-day mortality and morbidity assessed by the length of the intensive care unit (ICU) stay. We retrospectively enrolled patients undergoing congenital heart surgery in our institution. We modeled the ACC score as a continuous variable, mortality as a binary variable, and length of ICU stay as a censored variable. For each mortality and morbidity model we performed internal validation by bootstrapping and assessed overall performance by R(2), calibration by the calibration slope, and discrimination by the c index. Among all 1,454 patients enrolled, 30-day mortality rate was 3.4% and median length of ICU stay was 3 days. The ACC score strongly related to mortality, but related to length of ICU stay only during the first postoperative week. For the mortality model, R(2) = 0.24, calibration slope = 0.98, c index = 0.86, and 95% confidence interval was 0.82 to 0.91. For the morbidity model, R(2) = 0.094, calibration slope = 0.94, c index = 0.64, and 95% confidence interval was 0.62 to 0.66. The ACC score predicts 30-day mortality and length of ICU stay during the first postoperative week. The score is an adequate tool for complexity adjustment in the analysis of outcome after congenital heart surgery. Copyright © 2011 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  1. Differences in caregiver daily impression by sex, education and career length.

    PubMed

    Ae, Ryusuke; Kojo, Takao; Kotani, Kazuhiko; Okayama, Masanobu; Kuwabara, Masanari; Makino, Nobuko; Aoyama, Yasuko; Sano, Takashi; Nakamura, Yosikazu

    2017-03-01

    We previously proposed the concept of caregiver daily impression (CDI) as a practical tool for emergency triage. We herein assessed how CDI varies by sex, education and career length by determining CDI scores as quantitative outcome measures. We carried out a cross-sectional study using a self-reported questionnaire among caregivers in 20 long-term care facilities in Hyogo, Japan. A total of 10 CDI variables measured participants' previous experience of emergency transfers using a scale from 0-10. The resulting total was defined as the CDI score. We hypothetically considered that higher scores indicated greater caregiver focus. The CDI scores were compared by sex, education and career length using analysis of covariance. A total of 601 personal caregivers were evaluated (mean age 36.7 years; 36% men). The mean career length was 6.9 years, with the following groupings: 1-4 years (38%), 5-9 years (37%) and >10 years (24%). After adjustment for sex and education, the CDI scores for the variable, "poor eye contact," significantly differed between caregivers with ≥10 and <5 years of experience (scores of 5.0 ± 3.1 and 4.0 ± 2.7, respectively). The CDI scores for variables related to eyes tended to increase with experience, whereas other CDI scores decreased. Male caregivers focused on residents' eyes significantly more than did female caregivers. We found that the CDI variable, "poor eye contact," is influenced by career length. Caregivers with more experience attach more importance to their impression of residents' eyes than do those with less experience. Sex-related differences in CDI might also exist. Geriatr Gerontol Int 2016; 17: 410-415. © 2016 Japan Geriatrics Society.

  2. Millennial-scale variability during the last glacial in vegetation records from North America

    USGS Publications Warehouse

    Jiménez-Moreno, Gonzalo; Anderson, R. Scott; Desprat, S.; Grigg, L.D.; Grimm, E.C.; Heusser, L.E.; Jacobs, Brian F.; Lopez-Martinez, C.; Whitlock, C.L.; Willard, D.A.

    2010-01-01

    High-resolution pollen records from North America show that terrestrial environments were affected by Dansgaard-Oeschger (D-O) and Heinrich climate variability during the last glacial. In the western, more mountainous regions, these climate changes are generally observed in the pollen records as altitudinal movements of climate-sensitive plant species, whereas in the southeast, they are recorded as latitudinal shifts in vegetation. Heinrich (HS) and Greenland (GS) stadials are generally correlated with cold and dry climate and Greenland interstadials (GI) with warm-wet phases. The pollen records from North America confirm that vegetation responds rapidly to millennial-scale climate variability, although the difficulties in establishing independent age models for the pollen records make determination of the absolute phasing of the records to surface temperatures in Greenland somewhat uncertain. ?? 2009 Elsevier Ltd.

  3. Trends in Ocean Irradiance using a Radiative Model Forced with Terra Aerosols and Clouds

    NASA Technical Reports Server (NTRS)

    Gregg, Watson; Casey, Nancy; Romanou, Anastasia

    2010-01-01

    Aerosol and cloud information from MODIS on Terra provide enhanced capability to understand surface irradiance over the oceans and its variability. These relationships can be important for ocean biology and carbon cycles. An established radiative transfer model, the Ocean-Atmosphere Spectral Irradiance Model (OASIM) is used to describe ocean irradiance variability on seasonal to decadal time scales. The model is forced with information on aerosols and clouds from the MODIS sensor on Terra and Aqua. A 7-year record (2000-2006) showed no trends in global ocean surface irradiance or photosynthetic available irradiance (PAR). There were significant (P<0.05) negative trends in the Mediterranean Sea, tropical Pacific) and tropical Indian Oceans, of -7.0, -5.0 and -2.7 W/sq m respectively. Global interannual variability was also modest. Regional interannual variability was quite large in some ocean basins, where monthly excursions from climatology were often >20 W/sq m. The trends using MODIS data contrast with results from OASIM using liquid water path estimates from the International Satellite Cloud Climatology Project (ISCCP). Here, a global trend of -2 W/sq m was observed, largely dues to a large negative trend in the Antarctic -12 W/sq m. These results suggest the importance of the choice of liquid water path data sets in assessments of medium-length trends in ocean surface irradiance. The choices also impact the evaluation of changes in ocean biogeochemistry.

  4. Level walking in adults with and without Developmental Coordination Disorder: An analysis of movement variability.

    PubMed

    Du, Wenchong; Wilmut, Kate; Barnett, Anna L

    2015-10-01

    Several studies have shown that Developmental Coordination Disorder (DCD) is a condition that continues beyond childhood. Although adults with DCD report difficulties with dynamic balance, as well as frequent tripping and bumping into objects, there have been no specific studies on walking in this population. Some previous work has focused on walking in children with DCD but variation in the tasks and measures used has led to inconsistent findings. The aim of the current study therefore was to examine the characteristics of level walking in adults with and without DCD. Fifteen adults with DCD and 15 typically developing (TD) controls walked barefoot at a natural pace up and down an 11 m walkway for one minute. Foot placement measures and velocity and acceleration of the body were recorded, as well as measures of movement variability. The adults with DCD showed similar gait patterns to the TD group in terms of step length, step width, double support time and stride time. The DCD group also showed similar velocity and acceleration to the TD group in the medio-lateral, anterior-posterior and vertical direction. However, the DCD group exhibited greater variability in all foot placement and some body movement measures. The finding that adults with DCD have a reduced ability to produce consistent movement patterns is discussed in relation to postural control limitations and compared to variability of walking measures found in elderly populations. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Aftercare engagement: A review of the literature through the lens of disparities.

    PubMed

    Keefe, Kristen; Cardemil, Esteban V; Thompson, Matthew

    2017-02-01

    While prior research has well documented racial and ethnic disparities in mental health care broadly, significantly less attention has been given to possible disparities existing in the transition to aftercare. Grounded in Klinkenberg and Calsyn's (1996) framework, we review current research on aftercare, identify commonalities between the prior and current reviews, and highlight gaps for future research. We focus on variables pertinent to our understanding of racial/ethnic disparities. Articles were retrieved via PsycINFO, PubMed, PsycARTICLES, and Google Scholar. We targeted those written in English and conducted in the United States after 1996 that examined aftercare and disparities-related variables. Accumulating evidence across the 18 studies that we reviewed suggests that disparities exist in aftercare engagement. We found clear support for significant racial/ethnic effects on aftercare engagement, such that racial/ethnic minorities are typically more vulnerable to disengagement than Whites. In addition, we found modest support for the association between aftercare engagement and other individual- and community-level variables, including sex, insurance status, prior outpatient treatment, and residence in an urban versus rural setting. Moreover, extant qualitative research has identified barriers to aftercare engagement including stigma, low mental health literacy, and negative attitudes toward treatment. Finally, systems-level variables including assertive outreach efforts and reduced length of time on waitlists were identified as consistent predictors of engagement. Suggestions for future research and clinical implications are explored. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  6. Variability of simulants used in recreating stab events.

    PubMed

    Carr, D J; Wainwright, A

    2011-07-15

    Forensic investigators commonly use simulants/backing materials to mount fabrics and/or garments on when recreating damage due to stab events. Such work may be conducted in support of an investigation to connect a particular knife to a stabbing event by comparing the severance morphology obtained in the laboratory to that observed in the incident. There does not appear to have been a comparison of the effect of simulant type on the morphology of severances in fabrics and simulants, nor on the variability of simulants. This work investigates three simulants (pork, gelatine, expanded polystyrene), two knife blades (carving, bread), and how severances in the simulants and an apparel fabric typically used to manufacture T-shirts (single jersey) were affected by (i) simulant type and (ii) blade type. Severances were formed using a laboratory impact apparatus to ensure a consistent impact velocity and hence impact energy independently of the other variables. The impact velocity was chosen so that the force measured was similar to that measured in human performance trials. Force-time and energy-time curves were analysed and severance morphology (y, z directions) investigated. Simulant type and knife type significantly affected the critical forensic measurements of severance length (y direction) in the fabric and 'skin' (Tuftane). The use of EPS resulted in the lowest variability in data, further the severances recorded in both the fabric and Tuftane more accurately reflected the dimensions of the impacting knives. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  7. Image averaging of flexible fibrous macromolecules: the clathrin triskelion has an elastic proximal segment.

    PubMed

    Kocsis, E; Trus, B L; Steer, C J; Bisher, M E; Steven, A C

    1991-08-01

    We have developed computational techniques that allow image averaging to be applied to electron micrographs of filamentous molecules that exhibit tight and variable curvature. These techniques, which involve straightening by cubic-spline interpolation, image classification, and statistical analysis of the molecules' curvature properties, have been applied to purified brain clathrin. This trimeric filamentous protein polymerizes, both in vivo and in vitro, into a wide range of polyhedral structures. Contrasted by low-angle rotary shadowing, dissociated clathrin molecules appear as distinctive three-legged structures, called "triskelions" (E. Ungewickell and D. Branton (1981) Nature 289, 420). We find triskelion legs to vary from 35 to 62 nm in total length, according to an approximately bell-shaped distribution (mu = 51.6 nm). Peaks in averaged curvature profiles mark hinges or sites of enhanced flexibility. Such profiles, calculated for each length class, show that triskelion legs are flexible over their entire lengths. However, three curvature peaks are observed in every case: their locations define a proximal segment of systematically increasing length (14.0-19.0 nm), a mid-segment of fixed length (approximately 12 nm), and a rather variable end-segment (11.6-19.5 nm), terminating in a hinge just before the globular terminal domain (approximately 7.3 nm diameter). Thus, two major factors contribute to the overall variability in leg length: (1) stretching of the proximal segment and (2) stretching of the end-segment and/or scrolling of the terminal domain. The observed elasticity of the proximal segment may reflect phosphorylation of the clathrin light chains.

  8. Anthropometric parameters and sexual maturation in 12- to 15-year-old Estonian boys.

    PubMed

    Veldre, Gudrun; Jürimäe, Toivo

    2004-06-01

    The aims of this study were 1. to fix main sexual maturation signs and anthropometric measurements, and 2. to investigate relations between maturational status and main anthropometric parameters (i.e. skinfolds, girths, lengths, breadths/lengths) in 12-15-year old boys. In total, 361 boys from Tartu, Estonia, were studied. Body height and weight, 9 skinfolds, 13 girths, 8 lengths and 8 breadths/lengths were measured. Pubertal stages were determined according to the criteria described by Tanner (1962). Self-assessment of pubic hair (PH1-PH5) was used. Genital development (G1-G5) was estimated by palpating the left testis and matching the size of wood ovoid of the Prader orchidometer. Finally, boys were asked about oigarche (= age at the first ejaculation of sperm). Most of the measured anthropometric variables were significantly different in boys of different chronological age and sexual maturity groups. By linear discriminant analysis, the safety of separation of the chronological age groups was higher than by sexual maturation variables. Nonlinear discriminant analysis allowed to separate sexual maturity groups by anthropometric variables up to 99% security. It was concluded that though the growth and development of a child is highly individual, on an average the anthropometric characteristics alter very constantly with the increase of age and biological maturation. Our results indicated that there were some significant differences in the anthropometrical parameters depending on the chronological age and biological maturation. Mostly length and breadth/length parameters change during the studied age period in respect to sexual development subgroups of boys. The skinfold thicknesses were not changed or even decreased.

  9. 5 CFR 1605.12 - Removal of erroneous contributions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... negative adjustment record is posted by the TSP record keeper within one year of the date the erroneous... affected by the length of time the contributions have been in the account. (f)(1) If multiple negative...

  10. A frequency-domain seismic blind deconvolution based on Gini correlations

    NASA Astrophysics Data System (ADS)

    Wang, Zhiguo; Zhang, Bing; Gao, Jinghuai; Huo Liu, Qing

    2018-02-01

    In reflection seismic processing, the seismic blind deconvolution is a challenging problem, especially when the signal-to-noise ratio (SNR) of the seismic record is low and the length of the seismic record is short. As a solution to this ill-posed inverse problem, we assume that the reflectivity sequence is independent and identically distributed (i.i.d.). To infer the i.i.d. relationships from seismic data, we first introduce the Gini correlations (GCs) to construct a new criterion for the seismic blind deconvolution in the frequency-domain. Due to a unique feature, the GCs are robust in their higher tolerance of the low SNR data and less dependent on record length. Applications of the seismic blind deconvolution based on the GCs show their capacity in estimating the unknown seismic wavelet and the reflectivity sequence, whatever synthetic traces or field data, even with low SNR and short sample record.

  11. Positive predictive value of infective endocarditis in the Danish National Patient Registry: a validation study.

    PubMed

    Østergaard, Lauge; Adelborg, Kasper; Sundbøll, Jens; Pedersen, Lars; Loldrup Fosbøl, Emil; Schmidt, Morten

    2018-05-30

    The positive predictive value of an infective endocarditis diagnosis is approximately 80% in the Danish National Patient Registry. However, since infective endocarditis is a heterogeneous disease implying long-term intravenous treatment, we hypothesiszed that the positive predictive value varies by length of hospital stay. A total of 100 patients with first-time infective endocarditis in the Danish National Patient Registry were identified from January 2010 - December 2012 at the University hospital of Aarhus and regional hospitals of Herning and Randers. Medical records were reviewed. We calculated the positive predictive value according to admission length, and separately for patients with a cardiac implantable electronic device and a prosthetic heart valve using the Wilson score method. Among the 92 medical records available for review, the majority of the patients had admission length ⩾2 weeks. The positive predictive value increased with length of admission. In patients with admission length <2 weeks the positive predictive value was 65% while it was 90% for admission length ⩾2 weeks. The positive predictive value was 81% for patients with a cardiac implantable electronic device and 87% for patients with a prosthetic valve. The positive predictive value of the infective endocarditis diagnosis in the Danish National Patient Registry is high for patients with admission length ⩾2 weeks. Using this algorithm, the Danish National Patient Registry provides a valid source for identifying infective endocarditis for research.

  12. Climate driven variability and detectability of temporal trends in low flow indicators for Ireland

    NASA Astrophysics Data System (ADS)

    Hall, Julia; Murphy, Conor; Harrigan, Shaun

    2013-04-01

    Observational data from hydrological monitoring programs plays an important role in informing decision makers of changes in key hydrological variables. To analyse how changes in climate influence stream flow, undisturbed river basins with near-natural conditions limited from human influences are needed. This study analyses low flow indicators derived from observations from the Irish Reference Network. Within the trend analysis approach the influence of individual years or sub-periods on the detected trend are analysed using sequential trend tests on all possible periods (of at least 10 years in length) by varying the start and end dates of records for various indicators. Results from this study highlight that the current standard approach using fixed periods to determine long term trends is not appropriate as statistical significance and direction of trends from short term records do not persist continuously over entire record and can be heavily influenced by extremes within the record. The importance of longer records in contextualising short term trends derived from fixed-periods influenced by natural annual, inter-annual and multi-decadal variability is highlighted. Due to the low signal (trend) to noise (variability) ratio, the apparent trends derived from the low flow indicators cannot be used as confident guides to inform future water resources planning and decision making on climate change. Infact, some derived trends contradict expected climate change impacts and even small changes in study design can change the outcomes to a high degree. Therefore it is important not only to evaluate the magnitude of trends derived from monitoring data but also when a trend of a certain magnitude in a given indicator will be detectable to inform decision making or what changes might be required to detect trends for a certain significance level. In this study, the influence of observed variance in the monitoring records on the expected detection times for trends with a fixed magnitude are presented. Depending on the indicator selected, the sample variance and trend magnitude very different detection time estimates are obtained and in most cases not within the time required for anticipatory adaptation in the water resources sector. Additionally, the minimum changes in low flow indicators required to be detectable are large and changes are unlikely to be statistically detectable for many years. This means that water management and planning for anticipated future climatic changes will be required to take place without these changes being formally statistically detectable.Waiting for these trends to become formally detectable with the traditional statistical methods might not be an option for water resources management. Within the monitoring network, a considerable difference is apparent between stations in terms of detection times and changes required for detection. The existence of flow monitoring stations showing short detection times for specific indicators confirms the potential for identifying stations that may be first responders to climate induced changes. Identifying sentinel stations can increase the ability to more effectively optimise the deployment of resources for monitoring the influences of climatic change in a hydrometric reference network.

  13. Impact of renal anatomy on shock wave lithotripsy outcomes for lower pole kidney stones: results of a prospective multifactorial analysis controlled by computerized tomography.

    PubMed

    Torricelli, Fabio C M; Marchini, Giovanni S; Yamauchi, Fernando I; Danilovic, Alexandre; Vicentini, Fabio C; Srougi, Miguel; Monga, Manoj; Mazzucchi, Eduardo

    2015-06-01

    We evaluated which variables impact fragmentation and clearance of lower pole calculi after shock wave lithotripsy. We prospectively evaluated patients undergoing shock wave lithotripsy for a solitary 5 to 20 mm lower pole kidney stone between June 2012 and August 2014. Patient body mass index and abdominal waist circumference were recorded. One radiologist blinded to shock wave lithotripsy outcomes measured stone size, area and density, stone-to-skin distance, infundibular length, width and height, and infundibulopelvic angle based on baseline noncontrast computerized tomography. Fragmentation, success (defined as residual fragments less than 4 mm in asymptomatic patients) and the stone-free rate were evaluated by noncontrast computerized tomography 12 weeks postoperatively. Univariate and multivariate analysis was performed. A total of 100 patients were enrolled in the study. Mean stone size was 9.1 mm. Overall fragmentation, success and stone-free rates were 76%, 54% and 37%, respectively. On logistic regression body mass index (OR 1.27, 95% CI 1.11-1.49, p = 0.004) and stone density (OR 1.0026, 95% CI 1.0008-1.0046, p = 0.005) significantly impacted fragmentation. Stone size (OR 1.24, 95% CI 1.07-1.48, p = 0.039) and stone density (OR 1.0021, 95% CI 1.0007-1.0037, p = 0.012) impacted the success rate while stone size (OR 1.24, 95% CI 1.04-1.50, p = 0.029), stone density (OR 1.0015, 95% CI 1.0001-1.0032, p = 0.046) and infundibular length (OR 1.1035, 95% CI 1.015-1.217, p = 0.015) impacted the stone-free rate. The best outcomes were found in patients with a body mass index of 30 kg/m(2) or less, stones 10 mm or less and 900 HU or less, and an infundibular length of 25 mm or less. The coexistence of significant unfavorable variables led to a stone-free rate of less than 20%. Obese patients with higher than 10 mm density stones (greater than 900 HU) in the lower pole of the kidney with an infundibular length of greater than 25 mm should be discouraged from undergoing shock wave lithotripsy. Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  14. Maternity leave, women's employment, and marital incompatibility.

    PubMed

    Hyde, J S; Essex, M J; Clark, R; Klein, M H

    2001-09-01

    This research investigated the relationship between the length of women's maternity leave and marital incompatibility, in the context of other variables including the woman's employment, her dissatisfaction with the division of household labor, and her sense of role overload. Length of leave, work hours, and family salience were associated with several forms of dissatisfaction, which in turn predicted role overload. Role overload predicted increased marital incompatibility for experienced mothers but did not for first-time mothers, for whom discrepancies between preferred and actual child care were more important. Length of maternity leave showed significant interactions with other variables, supporting the hypothesis that a short leave is a risk factor that, when combined with another risk factor, contributes to personal and marital distress.

  15. Flutter suppression and stability analysis for a variable-span wing via morphing technology

    NASA Astrophysics Data System (ADS)

    Li, Wencheng; Jin, Dongping

    2018-01-01

    A morphing wing can enhance aerodynamic characteristics and control authority as an alternative to using ailerons. To use morphing technology for flutter suppression, the dynamical behavior and stability of a variable-span wing subjected to the supersonic aerodynamic loads are investigated numerically in this paper. An axially moving cantilever plate is employed to model the variable-span wing, in which the governing equations of motion are established via the Kane method and piston theory. A morphing strategy based on axially moving rates is proposed to suppress the flutter that occurs beyond the critical span length, and the flutter stability is verified by Floquet theory. Furthermore, the transient stability during the morphing motion is analyzed and the upper bound of the morphing rate is obtained. The simulation results indicate that the proposed morphing law, which is varying periodically with a proper amplitude, could accomplish the flutter suppression. Further, the upper bound of the morphing speed decreases rapidly once the span length is close to its critical span length.

  16. Tetragonal deformation of the hexagonal myofilament matrix in single skinned skeletal muscle fibres owing to change in sarcomere length.

    PubMed

    Schiereck, P; de Beer, E L; Grundeman, R L; Manussen, T; Kylstra, N; Bras, W

    1992-10-01

    Single skinned skeletal muscle fibres were immersed in solutions containing two different levels of activator calcium (pCa: 4.4; 6.0). Sarcomere length was varied from 1.6 to 3.5 microns and recorded by laser diffraction. Slack length was 2.0 microns. Small-angle equatorial X-ray diffraction patterns of relaxed and activated fibres at different sarcomere lengths were recorded using synchrotron radiation. The position and amplitude of the diffraction peaks were calculated from the spectra based on the hexagonal arrangement of the myofilament matrix, relating the position of the (1.0)- and (1.1)-diffraction peaks in this model by square root of 3. The diffraction peaks were fitted by five Gaussian functions (1.0, 1.1, 2.0, 2.1 and Z-line) and residual background was corrected by means of a hyperbola. The coupling of the position of the (1.0)- and (1.1)-peak was expressed as a factor: FAC = [d(1.0)/d(1.1)]/square root 3. In the relaxed state this coupling factor decreased at increasing sarcomere length (0.9880 +/- 0.002 at 2.0 microns; 0.900 +/- 0.01 at 3.5 microns). The coupling factor tends toward the one that will be obtained from the squared structure of actin filaments near the Z-discs. At shorter sarcomere lengths a decrease of the coupling factor has also been seen (0.9600 +/- 0.005 at 1.6 microns), giving rise to an increased uniform deformation of the hexagonal matrix, when sarcomere length is changed from slack length. From these experiments we conclude that a change in sarcomere length (from slack length) increases the deformation of the actin-myosin matrix to a tetragonal lattice.

  17. Short-term favorable weather conditions are an important control of interannual variability in carbon and water fluxes

    Treesearch

    Jakob Zscheischler; Simone Fatichi; Sebastian Wolf; Peter D. Blanken; Gil Bohrer; Ken Clark; Ankur R. Desai; David Hollinger; Trevor Keenan; Kimberly A. Novick; Sonia I. Seneviratne

    2016-01-01

    Ecosystem models often perform poorly in reproducing interannual variability in carbon and water fluxes, resulting in considerable uncertainty when estimating the land-carbon sink. While many aggregated variables (growing season length, seasonal precipitation, or temperature) have been suggested as predictors for interannual variability in carbon fluxes, their...

  18. Gender differences in adult foot shape: implications for shoe design.

    PubMed

    Wunderlich, R E; Cavanagh, P R

    2001-04-01

    To analyze gender differences in foot shape in a large sample of young individuals. Univariate t-tests and multivariate discriminant analyses were used to assess 1) significant differences between men and women for each foot and leg dimension, standardized to foot length, 2) the reliability of classification into gender classes using the absolute and standardized variable sets, and 3) the relative importance of each variable to the discrimination between men and women. Men have longer and broader feet than women for a given stature. After normalization of the measurements by foot length, men and women were found to differ significantly in two calf, five ankle, and four foot shape variables. Classification by gender using absolute values was correct at least 93% of the time. Using the variables standardized to foot length, gender was correctly classified 85% of the time. This study demonstrates that female feet and legs are not simply scaled-down versions of male feet but rather differ in a number of shape characteristics, particularly at the arch, the lateral side of the foot, the first toe, and the ball of the foot. These differences should be taken into account in the design and manufacture of women's sport shoes.

  19. A Study of Mexican Free-Tailed Bat Chirp Syllables: Bayesian Functional Mixed Models for Nonstationary Acoustic Time Series.

    PubMed

    Martinez, Josue G; Bohn, Kirsten M; Carroll, Raymond J; Morris, Jeffrey S

    2013-06-01

    We describe a new approach to analyze chirp syllables of free-tailed bats from two regions of Texas in which they are predominant: Austin and College Station. Our goal is to characterize any systematic regional differences in the mating chirps and assess whether individual bats have signature chirps. The data are analyzed by modeling spectrograms of the chirps as responses in a Bayesian functional mixed model. Given the variable chirp lengths, we compute the spectrograms on a relative time scale interpretable as the relative chirp position, using a variable window overlap based on chirp length. We use 2D wavelet transforms to capture correlation within the spectrogram in our modeling and obtain adaptive regularization of the estimates and inference for the regions-specific spectrograms. Our model includes random effect spectrograms at the bat level to account for correlation among chirps from the same bat, and to assess relative variability in chirp spectrograms within and between bats. The modeling of spectrograms using functional mixed models is a general approach for the analysis of replicated nonstationary time series, such as our acoustical signals, to relate aspects of the signals to various predictors, while accounting for between-signal structure. This can be done on raw spectrograms when all signals are of the same length, and can be done using spectrograms defined on a relative time scale for signals of variable length in settings where the idea of defining correspondence across signals based on relative position is sensible.

  20. 29 CFR 2400.4 - Collection and disclosure of personal information.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... solely as a statistical reporting or research record, and the record is to be transferred in a form that... bureau or commercial firm from which an employee is seeking credit: Length of service, job title, grade...

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