Sample records for verification sampling results

  1. 76 FR 41186 - Salmonella Verification Sampling Program: Response to Comments on New Agency Policies and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... Service [Docket No. FSIS-2008-0008] Salmonella Verification Sampling Program: Response to Comments on New... establishments that participate in SIP. The Agency intends to conduct its own unannounced, small- set sampling to... considering publishing verification sampling results for other product classes. In the 2006 Federal Register...

  2. Remaining Sites Verification Package for the 100-F-26:10, 1607-F3 Sanitary Sewer Pipelines (182-F, 183-F, and 151-F Sanitary Sewer Lines), Waste Site Reclassification Form 2007-028

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    L. M. Dittmer

    2007-12-03

    The 100-F-26:10 waste site includes sanitary sewer lines that serviced the former 182-F, 183-F, and 151-F Buildings. In accordance with this evaluation, the verification sampling results support a reclassification of this site to Interim Closed Out. The results of verification sampling show that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also demonstrate that residual contaminant concentrations are protective of groundwater and the Columbia River.

  3. Remaining Sites Verification Package for the 100-F-26:15 Miscellaneous Pipelines Associated with the 132-F-6, 1608-F Waste Water Pumping Station, Waste Site Reclassification Form 2007-031

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    L. M. Dittmer

    2008-03-18

    The 100-F-26:15 waste site consisted of the remnant portions of underground process effluent and floor drain pipelines that originated at the 105-F Reactor. In accordance with this evaluation, the verification sampling results support a reclassification of this site to Interim Closed Out. The results of verification sampling show that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also demonstrate that residual contaminant concentrations are protective of groundwater and the Columbia River.

  4. A robust method using propensity score stratification for correcting verification bias for binary tests

    PubMed Central

    He, Hua; McDermott, Michael P.

    2012-01-01

    Sensitivity and specificity are common measures of the accuracy of a diagnostic test. The usual estimators of these quantities are unbiased if data on the diagnostic test result and the true disease status are obtained from all subjects in an appropriately selected sample. In some studies, verification of the true disease status is performed only for a subset of subjects, possibly depending on the result of the diagnostic test and other characteristics of the subjects. Estimators of sensitivity and specificity based on this subset of subjects are typically biased; this is known as verification bias. Methods have been proposed to correct verification bias under the assumption that the missing data on disease status are missing at random (MAR), that is, the probability of missingness depends on the true (missing) disease status only through the test result and observed covariate information. When some of the covariates are continuous, or the number of covariates is relatively large, the existing methods require parametric models for the probability of disease or the probability of verification (given the test result and covariates), and hence are subject to model misspecification. We propose a new method for correcting verification bias based on the propensity score, defined as the predicted probability of verification given the test result and observed covariates. This is estimated separately for those with positive and negative test results. The new method classifies the verified sample into several subsamples that have homogeneous propensity scores and allows correction for verification bias. Simulation studies demonstrate that the new estimators are more robust to model misspecification than existing methods, but still perform well when the models for the probability of disease and probability of verification are correctly specified. PMID:21856650

  5. Formal verification of medical monitoring software using Z language: a representative sample.

    PubMed

    Babamir, Seyed Morteza; Borhani, Mehdi

    2012-08-01

    Medical monitoring systems are useful aids assisting physicians in keeping patients under constant surveillance; however, taking sound decision by the systems is a physician concern. As a result, verification of the systems behavior in monitoring patients is a matter of significant. The patient monitoring is undertaken by software in modern medical systems; so, software verification of modern medial systems have been noticed. Such verification can be achieved by the Formal Languages having mathematical foundations. Among others, the Z language is a suitable formal language has been used to formal verification of systems. This study aims to present a constructive method to verify a representative sample of a medical system by which the system is visually specified and formally verified against patient constraints stated in Z Language. Exploiting our past experience in formal modeling Continuous Infusion Insulin Pump (CIIP), we think of the CIIP system as a representative sample of medical systems in proposing our present study. The system is responsible for monitoring diabetic's blood sugar.

  6. Remaining Sites Verification Package for the 100-F-26:12, 1.8-m (72-in.) Main Process Sewer Pipeline, Waste Site Reclassification Form 2007-034

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    J. M. Capron

    2008-04-29

    The 100-F-26:12 waste site was an approximately 308-m-long, 1.8-m-diameter east-west-trending reinforced concrete pipe that joined the North Process Sewer Pipelines (100-F-26:1) and the South Process Pipelines (100-F-26:4) with the 1.8-m reactor cooling water effluent pipeline (100-F-19). In accordance with this evaluation, the verification sampling results support a reclassification of this site to Interim Closed Out. The results of verification sampling show that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also demonstrate that residual contaminant concentrations are protective of groundwater and the Columbia River.

  7. Verification of clinical samples, positive in AMPLICOR Neisseria gonorrhoeae polymerase chain reaction, by 16S rRNA and gyrA compared with culture.

    PubMed

    Airell, Asa; Lindbäck, Emma; Ataker, Ferda; Pörnull, Kirsti Jalakas; Wretlind, Bengt

    2005-06-01

    We compared 956 samples for AMPLICOR Neisseria gonorrhoeae polymerase chain reaction (PCR) (Roche) with species verification using the 16S rRNA gene to verification using gyrA gene. Control was the culture method. The gyrA verification uses pyrosequencing of the quinolone resistance-determining region of gyrA. Of 52 samples with optical density >/=0.2 in PCR, 27 were negative in culture, two samples from pharynx were false negative in culture and four samples from pharynx were false positives in verification with 16S rRNA. Twenty-five samples showed growth of gonococci, 18 of the corresponding PCR samples were verified by both methods; three urine samples were positive only in gyrA ; and one pharynx specimen was positive only in 16S rRNA. Three samples were lost. We conclude that AMPLICOR N. gonorrhoeae PCR with verification in gyrA gene can be considered as a diagnostic tool in populations with low prevalence of gonorrhoea and that pharynx specimens should not be analysed by PCR.

  8. Probabilistic Requirements (Partial) Verification Methods Best Practices Improvement. Variables Acceptance Sampling Calculators: Empirical Testing. Volume 2

    NASA Technical Reports Server (NTRS)

    Johnson, Kenneth L.; White, K. Preston, Jr.

    2012-01-01

    The NASA Engineering and Safety Center was requested to improve on the Best Practices document produced for the NESC assessment, Verification of Probabilistic Requirements for the Constellation Program, by giving a recommended procedure for using acceptance sampling by variables techniques as an alternative to the potentially resource-intensive acceptance sampling by attributes method given in the document. In this paper, the results of empirical tests intended to assess the accuracy of acceptance sampling plan calculators implemented for six variable distributions are presented.

  9. Remaining Sites Verification Package for the 116-C-3, 105-C Chemical Waste Tanks, Waste Site Reclassification Form 2008-002

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    L. M. Dittmer

    2008-01-31

    The 116-C-3 waste site consisted of two underground storage tanks designed to receive mixed waste from the 105-C Reactor Metals Examination Facility chemical dejacketing process. Confirmatory evaluation and subsequent characterization of the site determined that the southern tank contained approximately 34,000 L (9,000 gal) of dejacketing wastes, and that the northern tank was unused. In accordance with this evaluation, the verification sampling and modeling results support a reclassification of this site to Interim Closed Out. The results of verification sampling demonstrate that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils.more » The results also show that residual contaminant concentrations are protective of groundwater and the Columbia River.« less

  10. 47 CFR 73.151 - Field strength measurements to establish performance of directional antennas.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... verified either by field strength measurement or by computer modeling and sampling system verification. (a... specifically identified by the Commission. (c) Computer modeling and sample system verification of modeled... performance verified by computer modeling and sample system verification. (1) A matrix of impedance...

  11. Remaining Sites Verification Package for the 100-F-26:13, 108-F Drain Pipelines, Waste Site Reclassification Form 2005-011

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    L. M. Dittmer

    2008-03-03

    The 100-F-26:13 waste site is the network of process sewer pipelines that received effluent from the 108-F Biological Laboratory and discharged it to the 188-F Ash Disposal Area (126-F-1 waste site). The pipelines included one 0.15-m (6-in.)-, two 0.2-m (8-in.)-, and one 0.31-m (12-in.)-diameter vitrified clay pipe segments encased in concrete. In accordance with this evaluation, the verification sampling results support a reclassification of this site to Interim Closed Out. The results of verification sampling demonstrated that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also showed thatmore » residual contaminant concentrations are protective of groundwater and the Columbia River.« less

  12. An investigation of the effects of relevant samples and a comparison of verification versus discovery based lab design

    NASA Astrophysics Data System (ADS)

    Rieben, James C., Jr.

    This study focuses on the effects of relevance and lab design on student learning within the chemistry laboratory environment. A general chemistry conductivity of solutions experiment and an upper level organic chemistry cellulose regeneration experiment were employed. In the conductivity experiment, the two main variables studied were the effect of relevant (or "real world") samples on student learning and a verification-based lab design versus a discovery-based lab design. With the cellulose regeneration experiment, the effect of a discovery-based lab design vs. a verification-based lab design was the sole focus. Evaluation surveys consisting of six questions were used at three different times to assess student knowledge of experimental concepts. In the general chemistry laboratory portion of this study, four experimental variants were employed to investigate the effect of relevance and lab design on student learning. These variants consisted of a traditional (or verification) lab design, a traditional lab design using "real world" samples, a new lab design employing real world samples/situations using unknown samples, and the new lab design using real world samples/situations that were known to the student. Data used in this analysis were collected during the Fall 08, Winter 09, and Fall 09 terms. For the second part of this study a cellulose regeneration experiment was employed to investigate the effects of lab design. A demonstration creating regenerated cellulose "rayon" was modified and converted to an efficient and low-waste experiment. In the first variant students tested their products and verified a list of physical properties. In the second variant, students filled in a blank physical property chart with their own experimental results for the physical properties. Results from the conductivity experiment show significant student learning of the effects of concentration on conductivity and how to use conductivity to differentiate solution types with the use of real world samples. In the organic chemistry experiment, results suggest that the discovery-based design improved student retention of the chain length differentiation by physical properties relative to the verification-based design.

  13. Deductive Evaluation: Implicit Code Verification With Low User Burden

    NASA Technical Reports Server (NTRS)

    Di Vito, Ben L.

    2016-01-01

    We describe a framework for symbolically evaluating C code using a deductive approach that discovers and proves program properties. The framework applies Floyd-Hoare verification principles in its treatment of loops, with a library of iteration schemes serving to derive loop invariants. During evaluation, theorem proving is performed on-the-fly, obviating the generation of verification conditions normally needed to establish loop properties. A PVS-based prototype is presented along with results for sample C functions.

  14. The Mediation of Mothers’ Self-Fulfilling Effects on Their Children’s Alcohol Use: Self-Verification, Informational Conformity and Modeling Processes

    PubMed Central

    Madon, Stephanie; Guyll, Max; Buller, Ashley A.; Scherr, Kyle C.; Willard, Jennifer; Spoth, Richard

    2010-01-01

    This research examined whether self-fulfilling prophecy effects are mediated by self-verification, informational conformity, and modeling processes. The authors examined these mediational processes across multiple time frames with longitudinal data obtained from two samples of mother – child dyads (N1 = 487; N2 = 287). Children’s alcohol use was the outcome variable. The results provided consistent support for the mediational process of self-verification. In both samples and across several years of adolescence, there was a significant indirect effect of mothers’ beliefs on children’s alcohol use through children’s self-assessed likelihood of drinking alcohol in the future. Comparatively less support was found for informational conformity and modeling processes as mediators of mothers’ self-fulfilling effects. The potential for self-fulfilling prophecies to produce long lasting changes in targets’ behavior via self-verification processes are discussed. PMID:18665708

  15. The mediation of mothers' self-fulfilling effects on their children's alcohol use: self-verification, informational conformity, and modeling processes.

    PubMed

    Madon, Stephanie; Guyll, Max; Buller, Ashley A; Scherr, Kyle C; Willard, Jennifer; Spoth, Richard

    2008-08-01

    This research examined whether self-fulfilling prophecy effects are mediated by self-verification, informational conformity, and modeling processes. The authors examined these mediational processes across multiple time frames with longitudinal data obtained from two samples of mother-child dyads (N-sub-1 = 486; N-sub-2 = 287), with children's alcohol use as the outcome variable. The results provided consistent support for the mediational process of self-verification. In both samples and across several years of adolescence, there was a significant indirect effect of mothers' beliefs on children's alcohol use through children's self-assessed likelihood of drinking alcohol in the future. Comparatively less support was found for informational conformity and modeling processes as mediators of mothers' self-fulfilling effects. The potential for self-fulfilling prophecies to produce long-lasting changes in targets' behavior via self-verification processes are discussed. (c) 2008 APA, all rights reserved

  16. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - GROUNDWATER SAMPLING TECHNOLOGIES - QED ENVIRONMENTAL SYSTEMS INC. WELL WIZARD DEDICATED SAMPLING SYSTEM

    EPA Science Inventory

    The U.S. Environmental Protection Agency (EPA) has created the Environmental Technology Verification Program (ETV) to facilitate the deployment of innovative or improved environmental technologies through performance verification and dissemination of information. The goal of the ...

  17. Deductive Evaluation: Formal Code Analysis With Low User Burden

    NASA Technical Reports Server (NTRS)

    Di Vito, Ben. L

    2016-01-01

    We describe a framework for symbolically evaluating iterative C code using a deductive approach that automatically discovers and proves program properties. Although verification is not performed, the method can infer detailed program behavior. Software engineering work flows could be enhanced by this type of analysis. Floyd-Hoare verification principles are applied to synthesize loop invariants, using a library of iteration-specific deductive knowledge. When needed, theorem proving is interleaved with evaluation and performed on the fly. Evaluation results take the form of inferred expressions and type constraints for values of program variables. An implementation using PVS (Prototype Verification System) is presented along with results for sample C functions.

  18. Current status of verification practices in clinical biochemistry in Spain.

    PubMed

    Gómez-Rioja, Rubén; Alvarez, Virtudes; Ventura, Montserrat; Alsina, M Jesús; Barba, Núria; Cortés, Mariano; Llopis, María Antonia; Martínez, Cecilia; Ibarz, Mercè

    2013-09-01

    Verification uses logical algorithms to detect potential errors before laboratory results are released to the clinician. Even though verification is one of the main processes in all laboratories, there is a lack of standardization mainly in the algorithms used and the criteria and verification limits applied. A survey in clinical laboratories in Spain was conducted in order to assess the verification process, particularly the use of autoverification. Questionnaires were sent to the laboratories involved in the External Quality Assurance Program organized by the Spanish Society of Clinical Biochemistry and Molecular Pathology. Seven common biochemical parameters were included (glucose, cholesterol, triglycerides, creatinine, potassium, calcium, and alanine aminotransferase). Completed questionnaires were received from 85 laboratories. Nearly all the laboratories reported using the following seven verification criteria: internal quality control, instrument warnings, sample deterioration, reference limits, clinical data, concordance between parameters, and verification of results. The use of all verification criteria varied according to the type of verification (automatic, technical, or medical). Verification limits for these parameters are similar to biological reference ranges. Delta Check was used in 24% of laboratories. Most laboratories (64%) reported using autoverification systems. Autoverification use was related to laboratory size, ownership, and type of laboratory information system, but amount of use (percentage of test autoverified) was not related to laboratory size. A total of 36% of Spanish laboratories do not use autoverification, despite the general implementation of laboratory information systems, most of them, with autoverification ability. Criteria and rules for seven routine biochemical tests were obtained.

  19. Demonstration and Verification of a Turbine Power Generation System Utilizing Renewable Fuel: Landfill Gas

    DTIC Science & Technology

    2013-09-01

    33 4.7 SAMPLING RESULTS ...34 5.0 PERFORMANCE RESULTS ...PERFORMANCE RESULTS DISCUSSION ............................................................................ 39 5.2.1 Energy: Verify Power Production

  20. Integrated Verification Experiment data collected as part of the Los Alamos National Laboratory's Source Region Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fitzgerald, T.J.; Carlos, R.C.; Argo, P.E.

    As part of the integrated verification experiment (IVE), we deployed a network of hf ionospheric sounders to detect the effects of acoustic waves generated by surface ground motion following underground nuclear tests at the Nevada Test Site. The network sampled up to four geographic locations in the ionosphere from almost directly overhead of the surface ground zero out to a horizontal range of 60 km. We present sample results for four of the IVEs: Misty Echo, Texarkana, Mineral Quarry, and Bexar.

  1. An Approach to Biometric Verification Based on Human Body Communication in Wearable Devices

    PubMed Central

    Li, Jingzhen; Liu, Yuhang; Nie, Zedong; Qin, Wenjian; Pang, Zengyao; Wang, Lei

    2017-01-01

    In this paper, an approach to biometric verification based on human body communication (HBC) is presented for wearable devices. For this purpose, the transmission gain S21 of volunteer’s forearm is measured by vector network analyzer (VNA). Specifically, in order to determine the chosen frequency for biometric verification, 1800 groups of data are acquired from 10 volunteers in the frequency range 0.3 MHz to 1500 MHz, and each group includes 1601 sample data. In addition, to achieve the rapid verification, 30 groups of data for each volunteer are acquired at the chosen frequency, and each group contains only 21 sample data. Furthermore, a threshold-adaptive template matching (TATM) algorithm based on weighted Euclidean distance is proposed for rapid verification in this work. The results indicate that the chosen frequency for biometric verification is from 650 MHz to 750 MHz. The false acceptance rate (FAR) and false rejection rate (FRR) based on TATM are approximately 5.79% and 6.74%, respectively. In contrast, the FAR and FRR were 4.17% and 37.5%, 3.37% and 33.33%, and 3.80% and 34.17% using K-nearest neighbor (KNN) classification, support vector machines (SVM), and naive Bayesian method (NBM) classification, respectively. In addition, the running time of TATM is 0.019 s, whereas the running times of KNN, SVM and NBM are 0.310 s, 0.0385 s, and 0.168 s, respectively. Therefore, TATM is suggested to be appropriate for rapid verification use in wearable devices. PMID:28075375

  2. An Approach to Biometric Verification Based on Human Body Communication in Wearable Devices.

    PubMed

    Li, Jingzhen; Liu, Yuhang; Nie, Zedong; Qin, Wenjian; Pang, Zengyao; Wang, Lei

    2017-01-10

    In this paper, an approach to biometric verification based on human body communication (HBC) is presented for wearable devices. For this purpose, the transmission gain S21 of volunteer's forearm is measured by vector network analyzer (VNA). Specifically, in order to determine the chosen frequency for biometric verification, 1800 groups of data are acquired from 10 volunteers in the frequency range 0.3 MHz to 1500 MHz, and each group includes 1601 sample data. In addition, to achieve the rapid verification, 30 groups of data for each volunteer are acquired at the chosen frequency, and each group contains only 21 sample data. Furthermore, a threshold-adaptive template matching (TATM) algorithm based on weighted Euclidean distance is proposed for rapid verification in this work. The results indicate that the chosen frequency for biometric verification is from 650 MHz to 750 MHz. The false acceptance rate (FAR) and false rejection rate (FRR) based on TATM are approximately 5.79% and 6.74%, respectively. In contrast, the FAR and FRR were 4.17% and 37.5%, 3.37% and 33.33%, and 3.80% and 34.17% using K-nearest neighbor (KNN) classification, support vector machines (SVM), and naive Bayesian method (NBM) classification, respectively. In addition, the running time of TATM is 0.019 s, whereas the running times of KNN, SVM and NBM are 0.310 s, 0.0385 s, and 0.168 s, respectively. Therefore, TATM is suggested to be appropriate for rapid verification use in wearable devices.

  3. Ion mobility spectrometer, spectrometer analyte detection and identification verification system, and method

    DOEpatents

    Atkinson, David A.

    2002-01-01

    Methods and apparatus for ion mobility spectrometry and analyte detection and identification verification system are disclosed. The apparatus is configured to be used in an ion mobility spectrometer and includes a plurality of reactant reservoirs configured to contain a plurality of reactants which can be reacted with the sample to form adducts having varying ion mobilities. A carrier fluid, such as air or nitrogen, is used to carry the sample into the spectrometer. The plurality of reactants are configured to be selectively added to the carrier stream by use inlet and outlet manifolds in communication with the reagent reservoirs, the reservoirs being selectively isolatable by valves. The invention further includes a spectrometer having the reagent system described. In the method, a first reactant is used with the sample. Following a positive result, a second reactant is used to determine whether a predicted response occurs. The occurrence of the second predicted response tends to verify the existence of a component of interest within the sample. A third reactant can also be used to provide further verification of the existence of a component of interest. A library can be established of known responses of compounds of interest with various reactants and the results of a specific multi-reactant survey of a sample can be compared against the library to determine whether a component detected in the sample is likely to be a specific component of interest.

  4. Development of Sample Verification System for Sample Return Missions

    NASA Technical Reports Server (NTRS)

    Toda, Risaku; McKinney, Colin; Jackson, Shannon P.; Mojarradi, Mohammad; Trebi-Ollennu, Ashitey; Manohara, Harish

    2011-01-01

    This paper describes the development of a proof of-concept sample verification system (SVS) for in-situ mass measurement of planetary rock and soil sample in future robotic sample return missions. Our proof-of-concept SVS device contains a 10 cm diameter pressure sensitive elastic membrane placed at the bottom of a sample canister. The membrane deforms under the weight of accumulating planetary sample. The membrane is positioned in proximity to an opposing substrate with a narrow gap. The deformation of the membrane makes the gap to be narrower, resulting in increased capacitance between the two nearly parallel plates. Capacitance readout circuitry on a nearby printed circuit board (PCB) transmits data via a low-voltage differential signaling (LVDS) interface. The fabricated SVS proof-of-concept device has successfully demonstrated approximately 1pF/gram capacitance change

  5. Improved Detection Technique for Solvent Rinse Cleanliness Verification

    NASA Technical Reports Server (NTRS)

    Hornung, S. D.; Beeson, H. D.

    2001-01-01

    The NASA White Sands Test Facility (WSTF) has an ongoing effort to reduce or eliminate usage of cleaning solvents such as CFC-113 and its replacements. These solvents are used in the final clean and cleanliness verification processes for flight and ground support hardware, especially for oxygen systems where organic contaminants can pose an ignition hazard. For the final cleanliness verification in the standard process, the equivalent of one square foot of surface area of parts is rinsed with the solvent, and the final 100 mL of the rinse is captured. The amount of nonvolatile residue (NVR) in the solvent is determined by weight after the evaporation of the solvent. An improved process of sampling this rinse, developed at WSTF, requires evaporation of less than 2 mL of the solvent to make the cleanliness verification. Small amounts of the solvent are evaporated in a clean stainless steel cup, and the cleanliness of the stainless steel cup is measured using a commercially available surface quality monitor. The effectiveness of this new cleanliness verification technique was compared to the accepted NVR sampling procedures. Testing with known contaminants in solution, such as hydraulic fluid, fluorinated lubricants, and cutting and lubricating oils, was performed to establish a correlation between amount in solution and the process response. This report presents the approach and results and discusses the issues in establishing the surface quality monitor-based cleanliness verification.

  6. 40 CFR 1065.342 - Sample dryer verification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...)(2) to remove water from the sample gas, verify the performance upon installation, after major... before the sample gas reaches the analyzer. For example water can negatively interfere with a CLD's NOX... time. You may run this verification on the sample dryer alone, but you must use the maximum gas flow...

  7. 40 CFR 1065.342 - Sample dryer verification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...)(2) to remove water from the sample gas, verify the performance upon installation, after major... before the sample gas reaches the analyzer. For example water can negatively interfere with a CLD's NOX... time. You may run this verification on the sample dryer alone, but you must use the maximum gas flow...

  8. Determination of somatropin charged variants by capillary zone electrophoresis - optimisation, verification and implementation of the European pharmacopoeia method.

    PubMed

    Storms, S M; Feltus, A; Barker, A R; Joly, M-A; Girard, M

    2009-03-01

    Measurement of somatropin charged variants by isoelectric focusing was replaced with capillary zone electrophoresis in the January 2006 European Pharmacopoeia Supplement 5.3, based on results from an interlaboratory collaborative study. Due to incompatibilities and method-robustness issues encountered prior to verification, a number of method parameters required optimisation. As the use of a diode array detector at 195 nm or 200 nm led to a loss of resolution, a variable wavelength detector using a 200 nm filter was employed. Improved injection repeatability was obtained by increasing the injection time and pressure, and changing the sample diluent from water to running buffer. Finally, definition of capillary pre-treatment and rinse procedures resulted in more consistent separations over time. Method verification data are presented demonstrating linearity, specificity, repeatability, intermediate precision, limit of quantitation, sample stability, solution stability, and robustness. Based on these experiments, several modifications to the current method have been recommended and incorporated into the European Pharmacopoeia to help improve method performance across laboratories globally.

  9. Probabilistic Requirements (Partial) Verification Methods Best Practices Improvement. Variables Acceptance Sampling Calculators: Derivations and Verification of Plans. Volume 1

    NASA Technical Reports Server (NTRS)

    Johnson, Kenneth L.; White, K, Preston, Jr.

    2012-01-01

    The NASA Engineering and Safety Center was requested to improve on the Best Practices document produced for the NESC assessment, Verification of Probabilistic Requirements for the Constellation Program, by giving a recommended procedure for using acceptance sampling by variables techniques. This recommended procedure would be used as an alternative to the potentially resource-intensive acceptance sampling by attributes method given in the document. This document contains the outcome of the assessment.

  10. Reconstruction based finger-knuckle-print verification with score level adaptive binary fusion.

    PubMed

    Gao, Guangwei; Zhang, Lei; Yang, Jian; Zhang, Lin; Zhang, David

    2013-12-01

    Recently, a new biometrics identifier, namely finger knuckle print (FKP), has been proposed for personal authentication with very interesting results. One of the advantages of FKP verification lies in its user friendliness in data collection. However, the user flexibility in positioning fingers also leads to a certain degree of pose variations in the collected query FKP images. The widely used Gabor filtering based competitive coding scheme is sensitive to such variations, resulting in many false rejections. We propose to alleviate this problem by reconstructing the query sample with a dictionary learned from the template samples in the gallery set. The reconstructed FKP image can reduce much the enlarged matching distance caused by finger pose variations; however, both the intra-class and inter-class distances will be reduced. We then propose a score level adaptive binary fusion rule to adaptively fuse the matching distances before and after reconstruction, aiming to reduce the false rejections without increasing much the false acceptances. Experimental results on the benchmark PolyU FKP database show that the proposed method significantly improves the FKP verification accuracy.

  11. Integrated Verification Experiment data collected as part of the Los Alamos National Laboratory`s Source Region Program. Appendix D: Ionospheric measurements for IVEs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fitzgerald, T.J.; Carlos, R.C.; Argo, P.E.

    As part of the integrated verification experiment (IVE), we deployed a network of hf ionospheric sounders to detect the effects of acoustic waves generated by surface ground motion following underground nuclear tests at the Nevada Test Site. The network sampled up to four geographic locations in the ionosphere from almost directly overhead of the surface ground zero out to a horizontal range of 60 km. We present sample results for four of the IVEs: Misty Echo, Texarkana, Mineral Quarry, and Bexar.

  12. Alternative sample sizes for verification dose experiments and dose audits

    NASA Astrophysics Data System (ADS)

    Taylor, W. A.; Hansen, J. M.

    1999-01-01

    ISO 11137 (1995), "Sterilization of Health Care Products—Requirements for Validation and Routine Control—Radiation Sterilization", provides sampling plans for performing initial verification dose experiments and quarterly dose audits. Alternative sampling plans are presented which provide equivalent protection. These sampling plans can significantly reduce the cost of testing. These alternative sampling plans have been included in a draft ISO Technical Report (type 2). This paper examines the rational behind the proposed alternative sampling plans. The protection provided by the current verification and audit sampling plans is first examined. Then methods for identifying equivalent plans are highlighted. Finally, methods for comparing the cost associated with the different plans are provided. This paper includes additional guidance for selecting between the original and alternative sampling plans not included in the technical report.

  13. 40 CFR 1065.545 - Verification of proportional flow control for batch sampling.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... control for batch sampling. 1065.545 Section 1065.545 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Performing an Emission Test Over Specified Duty Cycles § 1065.545 Verification of proportional flow control for batch sampling. For any...

  14. Cleaning and Cleanliness Verification Techniques for Mars Returned Sample Handling

    NASA Technical Reports Server (NTRS)

    Mickelson, E. T.; Lindstrom, D. J.; Allton, J. H.; Hittle, J. D.

    2002-01-01

    Precision cleaning and cleanliness verification techniques are examined as a subset of a comprehensive contamination control strategy for a Mars sample return mission. Additional information is contained in the original extended abstract.

  15. 40 CFR 86.1845-04 - Manufacturer in-use verification testing requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... of test vehicles in the sample comply with the sample size requirements of this section. Any post... HDV must test, or cause to have tested, a specified number of vehicles. Such testing must be conducted... first test will be considered the official results for the test vehicle, regardless of any test results...

  16. Hyperplex-MRM: a hybrid multiple reaction monitoring method using mTRAQ/iTRAQ labeling for multiplex absolute quantification of human colorectal cancer biomarker.

    PubMed

    Yin, Hong-Rui; Zhang, Lei; Xie, Li-Qi; Huang, Li-Yong; Xu, Ye; Cai, San-Jun; Yang, Peng-Yuan; Lu, Hao-Jie

    2013-09-06

    Novel biomarker verification assays are urgently required to improve the efficiency of biomarker development. Benefitting from lower development costs, multiple reaction monitoring (MRM) has been used for biomarker verification as an alternative to immunoassay. However, in general MRM analysis, only one sample can be quantified in a single experiment, which restricts its application. Here, a Hyperplex-MRM quantification approach, which combined mTRAQ for absolute quantification and iTRAQ for relative quantification, was developed to increase the throughput of biomarker verification. In this strategy, equal amounts of internal standard peptides were labeled with mTRAQ reagents Δ0 and Δ8, respectively, as double references, while 4-plex iTRAQ reagents were used to label four different samples as an alternative to mTRAQ Δ4. From the MRM trace and MS/MS spectrum, total amounts and relative ratios of target proteins/peptides of four samples could be acquired simultaneously. Accordingly, absolute amounts of target proteins/peptides in four different samples could be achieved in a single run. In addition, double references were used to increase the reliability of the quantification results. Using this approach, three biomarker candidates, ademosylhomocysteinase (AHCY), cathepsin D (CTSD), and lysozyme C (LYZ), were successfully quantified in colorectal cancer (CRC) tissue specimens of different stages with high accuracy, sensitivity, and reproducibility. To summarize, we demonstrated a promising quantification method for high-throughput verification of biomarker candidates.

  17. Demonstration and Verification of a Turbine Power Generation System Utilizing Renewable Fuel: Landfill Gas

    DTIC Science & Technology

    2013-09-01

    17 5.6 SAMPLING RESULTS ........................................................................................ 18 6.0 PERFORMANCE...Page ii 8.0 IMPLEMENTATION ISSUES ........................................................................................ 37 8.1 FILTRATION ...15 iv LIST OF TABLES Page Table 1. Performance results

  18. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, GROUNDWATER SAMPLING TECHNOLOGIES, CLEAN ENVIRONMENT EQUIPMENT, SAMPLEASE BLADDER PUMP

    EPA Science Inventory

    The U.S. Environmental Protection Agency (EPA) has created the Environmental Technology Verification Program (ETV) to facilitate the deployment of innovative or improved environmental technologies through performance verification and dissemination of information. The goal of the...

  19. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, GROUNDWATER SAMPLING TECHNOLOGIES, BURGE ENVIRONMENTAL INC. MULTIPROBE 100

    EPA Science Inventory

    The U.S. Environmental Protection Agency (EPA) has created the Environmental Technology Verification Program (ETV) to facilitate the deployment of innovative or improved environmental technologies through performance verification and dissemination of information. The goal of the...

  20. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, ENVIRONMENTAL DECISION SUPPORT SOFTWARE, DECISION FX, INC. SAMPLING FX

    EPA Science Inventory

    The U.S. Environmental Protection Agency (EPA) has created the Environmental Technology Verification Program (ETV) to facilitate the deployment of innovative or improved environmental technologies through performance verification and dissemination of information. The goal of the...

  1. [Implication of inverse-probability weighting method in the evaluation of diagnostic test with verification bias].

    PubMed

    Kang, Leni; Zhang, Shaokai; Zhao, Fanghui; Qiao, Youlin

    2014-03-01

    To evaluate and adjust the verification bias existed in the screening or diagnostic tests. Inverse-probability weighting method was used to adjust the sensitivity and specificity of the diagnostic tests, with an example of cervical cancer screening used to introduce the Compare Tests package in R software which could be implemented. Sensitivity and specificity calculated from the traditional method and maximum likelihood estimation method were compared to the results from Inverse-probability weighting method in the random-sampled example. The true sensitivity and specificity of the HPV self-sampling test were 83.53% (95%CI:74.23-89.93)and 85.86% (95%CI: 84.23-87.36). In the analysis of data with randomly missing verification by gold standard, the sensitivity and specificity calculated by traditional method were 90.48% (95%CI:80.74-95.56)and 71.96% (95%CI:68.71-75.00), respectively. The adjusted sensitivity and specificity under the use of Inverse-probability weighting method were 82.25% (95% CI:63.11-92.62) and 85.80% (95% CI: 85.09-86.47), respectively, whereas they were 80.13% (95%CI:66.81-93.46)and 85.80% (95%CI: 84.20-87.41) under the maximum likelihood estimation method. The inverse-probability weighting method could effectively adjust the sensitivity and specificity of a diagnostic test when verification bias existed, especially when complex sampling appeared.

  2. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, GROUNDWATER SAMPLING TECHNOLOGIES, GEOLOG, INC., MICRO-FLO BLADDER PUMP MODEL 57400

    EPA Science Inventory

    The U.S. Environmental Protection Agency has created the Environmental Technology Verification Program to facilitate the deployment of innovative or improved environmental technologies through performance verification and dissemination of information. The goal of the ETV Program...

  3. Characterisation

    DTIC Science & Technology

    2007-03-01

    Characterisation. In Nanotechnology Aerospace Applications – 2006 (pp. 4-1 – 4-8). Educational Notes RTO-EN-AVT-129bis, Paper 4. Neuilly-sur-Seine, France: RTO...the Commercialisation Processes Concept IDEA Proof-of- Principle Trial Samples Engineering Verification Samples Design Verification Samples...SEIC Systems Engineering for commercialisation Design Houses, Engineering & R&D USERS & Integrators SE S U R Integrators Fabs & Wafer Processing Die

  4. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT: BAGHOUSE FILTRATION PRODUCTS—SOUTHERN FILTER MEDIA, LLC, PE-16/M-SPES FILTER SAMPLE

    EPA Science Inventory

    The U.S. EPA has created the Environmental Technology Verification program to facilitate the deployment of innovative or improved environmental technologies through performance verification and dissemination of information. The program tested the performance of baghouse filtrati...

  5. Feedback Seeking in Early Adolescence: Self-Enhancement or Self-Verification?

    PubMed

    Rosen, Lisa H; Principe, Connor P; Langlois, Judith H

    2013-02-13

    The authors examined whether early adolescents ( N = 90) solicit self-enhancing feedback (i.e., positive feedback) or self-verifying feedback (i.e., feedback congruent with self-views, even when these views are negative). Sixth, seventh, and eighth graders first completed a self-perception measure and then selected whether to receive positive or negative feedback from an unknown peer in different domains of self. Results were consistent with self-verification theory; adolescents who perceived themselves as having both strengths and weaknesses were more likely to seek negative feedback regarding a self-perceived weakness compared to a self-perceived strength. The authors found similar support for self-verification processes when they considered the entire sample regardless of perceived strengths and weaknesses; hierarchical linear modeling (HLM) examined the predictive power of ratings of self-perceived ability, certainty, and importance on feedback seeking for all participants and provided additional evidence of self-verification strivings in adolescence.

  6. Feedback Seeking in Early Adolescence: Self-Enhancement or Self-Verification?

    PubMed Central

    Rosen, Lisa H.; Principe, Connor P.; Langlois, Judith H.

    2012-01-01

    The authors examined whether early adolescents (N = 90) solicit self-enhancing feedback (i.e., positive feedback) or self-verifying feedback (i.e., feedback congruent with self-views, even when these views are negative). Sixth, seventh, and eighth graders first completed a self-perception measure and then selected whether to receive positive or negative feedback from an unknown peer in different domains of self. Results were consistent with self-verification theory; adolescents who perceived themselves as having both strengths and weaknesses were more likely to seek negative feedback regarding a self-perceived weakness compared to a self-perceived strength. The authors found similar support for self-verification processes when they considered the entire sample regardless of perceived strengths and weaknesses; hierarchical linear modeling (HLM) examined the predictive power of ratings of self-perceived ability, certainty, and importance on feedback seeking for all participants and provided additional evidence of self-verification strivings in adolescence. PMID:23543746

  7. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT; GROUNDWATER SAMPLING TECHNOLOGIES; W.L. GORE AND ASSOCIATES, INC., GORE-SORBER WATER QUALITY MONITORING

    EPA Science Inventory

    The U.S. Environmental Protection Agency (EPA) has created the Environmental Technology Verification Program (ETV) to facilitate the deployment of innovative or improved environmental technologies through performance verification and dissemination of information. The goal of the...

  8. Analysis of particulate contamination on tape lift samples from the VETA optical surfaces

    NASA Technical Reports Server (NTRS)

    Germani, Mark S.

    1992-01-01

    Particulate contamination analysis was carried out on samples taken from the Verification Engineering Test Article (VETA) x-ray detection system. A total of eighteen tape lift samples were taken from the VETA optical surfaces. Initially, the samples were tested using a scanning electron microscope. Additionally, particle composition was determined by energy dispersive x-ray spectrometry. Results are presented in terms of particle loading per sample.

  9. Remaining Sites Verification Package for the 1607-D4 Septic System, Waste Site Reclassification Form 2005-036

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    R. A. Carlson

    2006-02-23

    The 1607-D4 Septic System was a septic tank and tile field that received sanitary sewage from the 115-D/DR Gas Recirculation Facility. This septic system operated from 1944 to 1968. Decommissioning took place in 1985 and 1986 when all above-grade features were demolished and the tank backfilled. The results of verification sampling demonstrated that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also showed that residual contaminant concentrations are protective of groundwater and the Columbia River.

  10. Environmental Technology Verification Report for Abraxis Ecologenia® 17β-Estradiol (E2) Microplate Enzyme-Linked Immunosorbent Assay (ELISA) Test Kits

    EPA Science Inventory

    This verification test was conducted according to procedures specifiedin the Test/QA Planfor Verification of Enzyme-Linked Immunosorbent Assay (ELISA) Test Kis for the Quantitative Determination of Endocrine Disrupting Compounds (EDCs) in Aqueous Phase Samples. Deviations to the...

  11. Design and Verification of Critical Pressurised Windows for Manned Spaceflight

    NASA Astrophysics Data System (ADS)

    Lamoure, Richard; Busto, Lara; Novo, Francisco; Sinnema, Gerben; Leal, Mendes M.

    2014-06-01

    The Window Design for Manned Spaceflight (WDMS) project was tasked with establishing the state-of-art and explore possible improvements to the current structural integrity verification and fracture control methodologies for manned spacecraft windows.A critical review of the state-of-art in spacecraft window design, materials and verification practice was conducted. Shortcomings of the methodology in terms of analysis, inspection and testing were identified. Schemes for improving verification practices and reducing conservatism whilst maintaining the required safety levels were then proposed.An experimental materials characterisation programme was defined and carried out with the support of the 'Glass and Façade Technology Research Group', at the University of Cambridge. Results of the sample testing campaign were analysed, post-processed and subsequently applied to the design of a breadboard window demonstrator.Two Fused Silica glass window panes were procured and subjected to dedicated analyses, inspection and testing comprising both qualification and acceptance programmes specifically tailored to the objectives of the activity.Finally, main outcomes have been compiled into a Structural Verification Guide for Pressurised Windows in manned spacecraft, incorporating best practices and lessons learned throughout this project.

  12. Automated biowaste sampling system urine subsystem operating model, part 1

    NASA Technical Reports Server (NTRS)

    Fogal, G. L.; Mangialardi, J. K.; Rosen, F.

    1973-01-01

    The urine subsystem automatically provides for the collection, volume sensing, and sampling of urine from six subjects during space flight. Verification of the subsystem design was a primary objective of the current effort which was accomplished thru the detail design, fabrication, and verification testing of an operating model of the subsystem.

  13. Improving semi-text-independent method of writer verification using difference vector

    NASA Astrophysics Data System (ADS)

    Li, Xin; Ding, Xiaoqing

    2009-01-01

    The semi-text-independent method of writer verification based on the linear framework is a method that can use all characters of two handwritings to discriminate the writers in the condition of knowing the text contents. The handwritings are allowed to just have small numbers of even totally different characters. This fills the vacancy of the classical text-dependent methods and the text-independent methods of writer verification. Moreover, the information, what every character is, is used for the semi-text-independent method in this paper. Two types of standard templates, generated from many writer-unknown handwritten samples and printed samples of each character, are introduced to represent the content information of each character. The difference vectors of the character samples are gotten by subtracting the standard templates from the original feature vectors and used to replace the original vectors in the process of writer verification. By removing a large amount of content information and remaining the style information, the verification accuracy of the semi-text-independent method is improved. On a handwriting database involving 30 writers, when the query handwriting and the reference handwriting are composed of 30 distinct characters respectively, the average equal error rate (EER) of writer verification reaches 9.96%. And when the handwritings contain 50 characters, the average EER falls to 6.34%, which is 23.9% lower than the EER of not using the difference vectors.

  14. The Mars Science Laboratory Organic Check Material

    NASA Astrophysics Data System (ADS)

    Conrad, Pamela G.; Eigenbrode, Jennifer L.; Von der Heydt, Max O.; Mogensen, Claus T.; Canham, John; Harpold, Dan N.; Johnson, Joel; Errigo, Therese; Glavin, Daniel P.; Mahaffy, Paul R.

    2012-09-01

    Mars Science Laboratory's Curiosity rover carries a set of five external verification standards in hermetically sealed containers that can be sampled as would be a Martian rock, by drilling and then portioning into the solid sample inlet of the Sample Analysis at Mars (SAM) suite. Each organic check material (OCM) canister contains a porous ceramic solid, which has been doped with a fluorinated hydrocarbon marker that can be detected by SAM. The purpose of the OCM is to serve as a verification tool for the organic cleanliness of those parts of the sample chain that cannot be cleaned other than by dilution, i.e., repeated sampling of Martian rock. SAM possesses internal calibrants for verification of both its performance and its internal cleanliness, and the OCM is not used for that purpose. Each OCM unit is designed for one use only, and the choice to do so will be made by the project science group (PSG).

  15. Evaluation of the 29-km Eta Model. Part 1; Objective Verification at Three Selected Stations

    NASA Technical Reports Server (NTRS)

    Nutter, Paul A.; Manobianco, John; Merceret, Francis J. (Technical Monitor)

    1998-01-01

    This paper describes an objective verification of the National Centers for Environmental Prediction (NCEP) 29-km eta model from May 1996 through January 1998. The evaluation was designed to assess the model's surface and upper-air point forecast accuracy at three selected locations during separate warm (May - August) and cool (October - January) season periods. In order to enhance sample sizes available for statistical calculations, the objective verification includes two consecutive warm and cool season periods. Systematic model deficiencies comprise the larger portion of the total error in most of the surface forecast variables that were evaluated. The error characteristics for both surface and upper-air forecasts vary widely by parameter, season, and station location. At upper levels, a few characteristic biases are identified. Overall however, the upper-level errors are more nonsystematic in nature and could be explained partly by observational measurement uncertainty. With a few exceptions, the upper-air results also indicate that 24-h model error growth is not statistically significant. In February and August 1997, NCEP implemented upgrades to the eta model's physical parameterizations that were designed to change some of the model's error characteristics near the surface. The results shown in this paper indicate that these upgrades led to identifiable and statistically significant changes in forecast accuracy for selected surface parameters. While some of the changes were expected, others were not consistent with the intent of the model updates and further emphasize the need for ongoing sensitivity studies and localized statistical verification efforts. Objective verification of point forecasts is a stringent measure of model performance, but when used alone, is not enough to quantify the overall value that model guidance may add to the forecast process. Therefore, results from a subjective verification of the meso-eta model over the Florida peninsula are discussed in the companion paper by Manobianco and Nutter. Overall verification results presented here and in part two should establish a reasonable benchmark from which model users and developers may pursue the ongoing eta model verification strategies in the future.

  16. Remaining Sites Verification Package for the 1607-F7, 141-M Building Septic Tank, Waste Site Reclassification Form 2006-040

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    L. M. Dittmer

    2006-10-19

    The 1607-F7, 141-M Building Septic Tank waste site was a septic tank and drain field that received sanitary sewage from the former 141-M Building. Remedial action was performed in August and November 2005. The results of verification sampling demonstrate that residual contaminant concentrations support future unrestricted land uses that can be represented by a rural-residential scenario. These results also show that residual concentrations support unrestricted future use of shallow zone soil and that contaminant levels remaining in the soil are protective of groundwater and the Columbia River.

  17. INDEPENDENT VERIFICATION SURVEY REPORT FOR ZONE 1 OF THE EAST TENNESSEE TECHNOLOGY PARK IN OAK RIDGE, TENNESSEE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    King, David A.

    2012-08-16

    Oak Ridge Associated Universities (ORAU) conducted in-process inspections and independent verification (IV) surveys in support of DOE's remedial efforts in Zone 1 of East Tennessee Technology Park (ETTP) in Oak Ridge, Tennessee. Inspections concluded that the remediation contractor's soil removal and survey objectives were satisfied and the dynamic verification strategy (DVS) was implemented as designed. Independent verification (IV) activities included gamma walkover surveys and soil sample collection/analysis over multiple exposure units (EUs).

  18. Pyroelectric effect in tryglicyne sulphate single crystals - Differential measurement method

    NASA Astrophysics Data System (ADS)

    Trybus, M.

    2018-06-01

    A simple mathematical model of the pyroelectric phenomenon was used to explain the electric response of the TGS (triglycine sulphate) samples in the linear heating process in ferroelectric and paraelectric phases. Experimental verification of mathematical model was realized. TGS single crystals were grown and four electrode samples were fabricated. Differential measurements of the pyroelectric response of two different regions of the samples were performed and the results were compared with data obtained from the model. Experimental results are in good agreement with model calculations.

  19. Feasibility of biochemical verification in a web-based smoking cessation study.

    PubMed

    Cha, Sarah; Ganz, Ollie; Cohn, Amy M; Ehlke, Sarah J; Graham, Amanda L

    2017-10-01

    Cogent arguments have been made against the need for biochemical verification in population-based studies with low-demand characteristics. Despite this fact, studies involving digital interventions (low-demand) are often required in peer review to report biochemically verified abstinence. To address this discrepancy, we examined the feasibility and costs of biochemical verification in a web-based study conducted with a national sample. Participants were 600U.S. adult current smokers who registered on a web-based smoking cessation program and completed surveys at baseline and 3months. Saliva sampling kits were sent to participants who reported 7-day abstinence at 3months, and analyzed for cotinine. The response rate at 3-months was 41.2% (n=247): 93 participants reported 7-day abstinence (38%) and were mailed a saliva kit (71% returned). The discordance rate was 36.4%. Participants with discordant responses were more likely to report 3-month use of nicotine replacement therapy or e-cigarettes than those with concordant responses (79.2% vs. 45.2%, p=0.007). The total cost of saliva sampling was $8280 ($125/sample). Biochemical verification was both time- and cost-intensive, and yielded a relatively small number of samples due to low response rates and use of other nicotine products during the follow-up period. There was a high rate of discordance of self-reported abstinence and saliva testing. Costs for data collection may be prohibitive for studies with large sample sizes or limited budgets. Our findings echo previous statements that biochemical verification is not necessary in population-based studies, and add evidence specific to technology-based studies. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Self-Verification and Depressive Symptoms in Marriage and Courtship: A Multiple Pathway Model.

    ERIC Educational Resources Information Center

    Katz, Jennifer; Beach, Steven R. H.

    1997-01-01

    Examines whether self-verifying feedback may lead to decreased depressive symptoms. Results, based on 138 married women and 258 dating women, showed full mediational effects in the married sample and partial effects in the dating sample. Findings suggest that partner self-verifying feedback may intensify the effect of self-esteem on depression.…

  1. Rapid determination of alpha emitters using Actinide resin.

    PubMed

    Navarro, N; Rodriguez, L; Alvarez, A; Sancho, C

    2004-01-01

    The European Commission has recently published the recommended radiological protection criteria for the clearance of building and building rubble from the dismantling of nuclear installations. Radionuclide specific clearance levels for actinides are very low (between 0.1 and 1 Bq g(-1)). The prevalence of natural radionuclides in rubble materials makes the verification of these levels by direct alpha counting impossible. The capability of Actinide resin (Eichrom Industries, Inc.) for extracting plutonium and americium from rubble samples has been tested in this work. Besides a strong affinity for actinides in the tri, tetra and hexavalent oxidation states, this extraction chromatographic resin presents an easy recovery of absorbed radionuclides. The retention capability was evaluated on rubble samples spiked with certified radionuclide standards (239Pu and 241Am). Samples were leached with nitric acid, passed through a chromatographic column containing the resin and the elution fraction was measured by LSC. Actinide retention varies from 60% to 80%. Based on these results, a rapid method for the verification of clearance levels for actinides in rubble samples is proposed.

  2. Development of a universal metabolome-standard method for long-term LC-MS metabolome profiling and its application for bladder cancer urine-metabolite-biomarker discovery.

    PubMed

    Peng, Jun; Chen, Yi-Ting; Chen, Chien-Lun; Li, Liang

    2014-07-01

    Large-scale metabolomics study requires a quantitative method to generate metabolome data over an extended period with high technical reproducibility. We report a universal metabolome-standard (UMS) method, in conjunction with chemical isotope labeling liquid chromatography-mass spectrometry (LC-MS), to provide long-term analytical reproducibility and facilitate metabolome comparison among different data sets. In this method, UMS of a specific type of sample labeled by an isotope reagent is prepared a priori. The UMS is spiked into any individual samples labeled by another form of the isotope reagent in a metabolomics study. The resultant mixture is analyzed by LC-MS to provide relative quantification of the individual sample metabolome to UMS. UMS is independent of a study undertaking as well as the time of analysis and useful for profiling the same type of samples in multiple studies. In this work, the UMS method was developed and applied for a urine metabolomics study of bladder cancer. UMS of human urine was prepared by (13)C2-dansyl labeling of a pooled sample from 20 healthy individuals. This method was first used to profile the discovery samples to generate a list of putative biomarkers potentially useful for bladder cancer detection and then used to analyze the verification samples about one year later. Within the discovery sample set, three-month technical reproducibility was examined using a quality control sample and found a mean CV of 13.9% and median CV of 9.4% for all the quantified metabolites. Statistical analysis of the urine metabolome data showed a clear separation between the bladder cancer group and the control group from the discovery samples, which was confirmed by the verification samples. Receiver operating characteristic (ROC) test showed that the area under the curve (AUC) was 0.956 in the discovery data set and 0.935 in the verification data set. These results demonstrated the utility of the UMS method for long-term metabolomics and discovering potential metabolite biomarkers for diagnosis of bladder cancer.

  3. Results from Mechanical Testing of Silicon Carbide for Space Applications: Non-Destructive Evalution Samples and MISSE-6 Experiment Samples

    DTIC Science & Technology

    2010-06-07

    the materials properties of silicon carbide plates”, S. Kenderian et al., 2009 SPIE Proceedings, vol. 7425 • Materials – 10” x 16” SiC plates...CONFERENCE PROCEEDING 3. DATES COVERED (From - To) 2008-2010 4. TITLE AND SUBTITLE Results from Mechanical Testing of Silicon Carbide for Space...for silicon carbide optical systems that covers material verification through system development. Recent laboratory results for testing of materials

  4. Diode step stress program, JANTX1N5614

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The reliability of switching diode JANTX1N5614 was tested. The effect of power/temperature step stress on the diode was determined. Control sample units were maintained for verification of the electrical parametric testing. Results are reported.

  5. A simple visual ethanol biosensor based on alcohol oxidase immobilized onto polyaniline film for halal verification of fermented beverage samples.

    PubMed

    Kuswandi, Bambang; Irmawati, Titi; Hidayat, Moch Amrun; Jayus; Ahmad, Musa

    2014-01-27

    A simple visual ethanol biosensor based on alcohol oxidase (AOX) immobilised onto polyaniline (PANI) film for halal verification of fermented beverage samples is described. This biosensor responds to ethanol via a colour change from green to blue, due to the enzymatic reaction of ethanol that produces acetaldehyde and hydrogen peroxide, when the latter oxidizes the PANI film. The procedure to obtain this biosensor consists of the immobilization of AOX onto PANI film by adsorption. For the immobilisation, an AOX solution is deposited on the PANI film and left at room temperature until dried (30 min). The biosensor was constructed as a dip stick for visual and simple use. The colour changes of the films have been scanned and analysed using image analysis software (i.e., ImageJ) to study the characteristics of the biosensor's response toward ethanol. The biosensor has a linear response in an ethanol concentration range of 0.01%-0.8%, with a correlation coefficient (r) of 0.996. The limit detection of the biosensor was 0.001%, with reproducibility (RSD) of 1.6% and a life time up to seven weeks when stored at 4 °C. The biosensor provides accurate results for ethanol determination in fermented drinks and was in good agreement with the standard method (gas chromatography) results. Thus, the biosensor could be used as a simple visual method for ethanol determination in fermented beverage samples that can be useful for Muslim community for halal verification.

  6. Cleaning verification: Exploring the effect of the cleanliness of stainless steel surface on sample recovery.

    PubMed

    Haidar Ahmad, Imad A; Tam, James; Li, Xue; Duffield, William; Tarara, Thomas; Blasko, Andrei

    2017-02-05

    The parameters affecting the recovery of pharmaceutical residues from the surface of stainless steel coupons for quantitative cleaning verification method development have been studied, including active pharmaceutical ingredient (API) level, spiking procedure, API/excipient ratio, analyst-to-analyst variability, inter-day variability, and cleaning procedure of the coupons. The lack of a well-defined procedure that consistently cleaned coupon surface was identified as the major contributor to low and variable recoveries. Assessment of acid, base, and oxidant washes, as well as the order of treatment, showed that a base-water-acid-water-oxidizer-water wash procedure resulted in consistent, accurate spiked recovery (>90%) and reproducible results (S rel ≤4%). By applying this cleaning procedure to the previously used coupons that failed the cleaning acceptance criteria, multiple analysts were able to obtain consistent recoveries from day-to-day for different APIs, and API/excipient ratios at various spike levels. We successfully applied our approach for cleaning verification of small molecules (MW<1000Da) as well as large biomolecules (MW up to 50,000Da). Method robustness was greatly influenced by the sample preparation procedure, especially for analyses using total organic carbon (TOC) determination. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Statistical Design for Biospecimen Cohort Size in Proteomics-based Biomarker Discovery and Verification Studies

    PubMed Central

    Skates, Steven J.; Gillette, Michael A.; LaBaer, Joshua; Carr, Steven A.; Anderson, N. Leigh; Liebler, Daniel C.; Ransohoff, David; Rifai, Nader; Kondratovich, Marina; Težak, Živana; Mansfield, Elizabeth; Oberg, Ann L.; Wright, Ian; Barnes, Grady; Gail, Mitchell; Mesri, Mehdi; Kinsinger, Christopher R.; Rodriguez, Henry; Boja, Emily S.

    2014-01-01

    Protein biomarkers are needed to deepen our understanding of cancer biology and to improve our ability to diagnose, monitor and treat cancers. Important analytical and clinical hurdles must be overcome to allow the most promising protein biomarker candidates to advance into clinical validation studies. Although contemporary proteomics technologies support the measurement of large numbers of proteins in individual clinical specimens, sample throughput remains comparatively low. This problem is amplified in typical clinical proteomics research studies, which routinely suffer from a lack of proper experimental design, resulting in analysis of too few biospecimens to achieve adequate statistical power at each stage of a biomarker pipeline. To address this critical shortcoming, a joint workshop was held by the National Cancer Institute (NCI), National Heart, Lung and Blood Institute (NHLBI), and American Association for Clinical Chemistry (AACC), with participation from the U.S. Food and Drug Administration (FDA). An important output from the workshop was a statistical framework for the design of biomarker discovery and verification studies. Herein, we describe the use of quantitative clinical judgments to set statistical criteria for clinical relevance, and the development of an approach to calculate biospecimen sample size for proteomic studies in discovery and verification stages prior to clinical validation stage. This represents a first step towards building a consensus on quantitative criteria for statistical design of proteomics biomarker discovery and verification research. PMID:24063748

  8. Statistical design for biospecimen cohort size in proteomics-based biomarker discovery and verification studies.

    PubMed

    Skates, Steven J; Gillette, Michael A; LaBaer, Joshua; Carr, Steven A; Anderson, Leigh; Liebler, Daniel C; Ransohoff, David; Rifai, Nader; Kondratovich, Marina; Težak, Živana; Mansfield, Elizabeth; Oberg, Ann L; Wright, Ian; Barnes, Grady; Gail, Mitchell; Mesri, Mehdi; Kinsinger, Christopher R; Rodriguez, Henry; Boja, Emily S

    2013-12-06

    Protein biomarkers are needed to deepen our understanding of cancer biology and to improve our ability to diagnose, monitor, and treat cancers. Important analytical and clinical hurdles must be overcome to allow the most promising protein biomarker candidates to advance into clinical validation studies. Although contemporary proteomics technologies support the measurement of large numbers of proteins in individual clinical specimens, sample throughput remains comparatively low. This problem is amplified in typical clinical proteomics research studies, which routinely suffer from a lack of proper experimental design, resulting in analysis of too few biospecimens to achieve adequate statistical power at each stage of a biomarker pipeline. To address this critical shortcoming, a joint workshop was held by the National Cancer Institute (NCI), National Heart, Lung, and Blood Institute (NHLBI), and American Association for Clinical Chemistry (AACC) with participation from the U.S. Food and Drug Administration (FDA). An important output from the workshop was a statistical framework for the design of biomarker discovery and verification studies. Herein, we describe the use of quantitative clinical judgments to set statistical criteria for clinical relevance and the development of an approach to calculate biospecimen sample size for proteomic studies in discovery and verification stages prior to clinical validation stage. This represents a first step toward building a consensus on quantitative criteria for statistical design of proteomics biomarker discovery and verification research.

  9. Evaluating the Impact of Various Parameters on the Gamma Index Values of 2D Diode Array in IMRT Verification

    PubMed Central

    Jabbari, Keyvan; Pashaei, Fakhereh; Ay, Mohammad R.; Amouheidari, Alireza; Tavakoli, Mohammad B.

    2018-01-01

    Background: MapCHECK2 is a two-dimensional diode arrays planar dosimetry verification system. Dosimetric results are evaluated with gamma index. This study aims to provide comprehensive information on the impact of various factors on the gamma index values of MapCHECK2, which is mostly used for IMRT dose verification. Methods: Seven fields were planned for 6 and 18 MV photons. The azimuthal angle is defined as any rotation of collimators or the MapCHECK2 around the central axis, which was varied from 5 to −5°. The gantry angle was changed from −8 to 8°. Isodose sampling resolution was studied in the range of 0.5 to 4 mm. The effects of additional buildup on gamma index in three cases were also assessed. Gamma test acceptance criteria were 3%/3 mm. Results: The change of azimuthal angle in 5° interval reduced gamma index value by about 9%. The results of putting buildups of various thicknesses on the MapCHECK2 surface showed that gamma index was generally improved in thicker buildup, especially for 18 MV. Changing the sampling resolution from 4 to 2 mm resulted in an increase in gamma index by about 3.7%. The deviation of the gantry in 8° intervals in either directions changed the gamma index only by about 1.6% for 6 MV and 2.1% for 18 MV. Conclusion: Among the studied parameters, the azimuthal angle is one of the most effective factors on gamma index value. The gantry angle deviation and sampling resolution are less effective on gamma index value reduction. PMID:29535922

  10. Multi-canister overpack project -- verification and validation, MCNP 4A

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goldmann, L.H.

    This supporting document contains the software verification and validation (V and V) package used for Phase 2 design of the Spent Nuclear Fuel Multi-Canister Overpack. V and V packages for both ANSYS and MCNP are included. Description of Verification Run(s): This software requires that it be compiled specifically for the machine it is to be used on. Therefore to facilitate ease in the verification process the software automatically runs 25 sample problems to ensure proper installation and compilation. Once the runs are completed the software checks for verification by performing a file comparison on the new output file and themore » old output file. Any differences between any of the files will cause a verification error. Due to the manner in which the verification is completed a verification error does not necessarily indicate a problem. This indicates that a closer look at the output files is needed to determine the cause of the error.« less

  11. Aqueous Cleaning and Validation for Space Shuttle Propulsion Hardware at the White Sands Test Facility

    NASA Technical Reports Server (NTRS)

    Hornung, Steven D.; Biesinger, Paul; Kirsch, Mike; Beeson, Harold; Leuders, Kathy

    1999-01-01

    The NASA White Sands Test Facility (WSTF) has developed an entirely aqueous final cleaning and verification process to replace the current chlorofluorocarbon (CFC) 113 based process. This process has been accepted for final cleaning and cleanliness verification of WSTF ground support equipment. The aqueous process relies on ultrapure water at 50 C (323 K) and ultrasonic agitation for removal of organic compounds and particulate. The cleanliness is verified bv determining the total organic carbon (TOC) content and filtration with particulate counting. The effectiveness of the aqueous methods for detecting hydrocarbon contamination and particulate was compared to the accepted CFC 113 sampling procedures. Testing with known contaminants, such as hydraulic fluid and cutting and lubricating oils, to establish a correlation between aqueous TOC and CFC 113 nonvolatile residue (NVR) was performed. Particulate sampling on cleaned batches of hardware that were randomly separated and sampled by the two methods was performed. This paper presents the approach and results, and discusses the issues in establishing the equivalence of aqueous sampling to CFC 113 sampling, while describing the approach for implementing aqueous techniques on Space Shuttle Propulsion hardware.

  12. An experimental verification of laser-velocimeter sampling bias and its correction

    NASA Technical Reports Server (NTRS)

    Johnson, D. A.; Modarress, D.; Owen, F. K.

    1982-01-01

    The existence of 'sampling bias' in individual-realization laser velocimeter measurements is experimentally verified and shown to be independent of sample rate. The experiments were performed in a simple two-stream mixing shear flow with the standard for comparison being laser-velocimeter results obtained under continuous-wave conditions. It is also demonstrated that the errors resulting from sampling bias can be removed by a proper interpretation of the sampling statistics. In addition, data obtained in a shock-induced separated flow and in the near-wake of airfoils are presented, both bias-corrected and uncorrected, to illustrate the effects of sampling bias in the extreme.

  13. Self-verification and social anxiety: preference for negative social feedback and low social self-esteem.

    PubMed

    Valentiner, David P; Skowronski, John J; McGrath, Patrick B; Smith, Sarah A; Renner, Kerry A

    2011-10-01

    A self-verification model of social anxiety views negative social self-esteem as a core feature of social anxiety. This core feature is proposed to be maintained through self-verification processes, such as by leading individuals with negative social self-esteem to prefer negative social feedback. This model is tested in two studies. In Study 1, questionnaires were administered to a college sample (N = 317). In Study 2, questionnaires were administered to anxiety disordered patients (N = 62) before and after treatment. Study 1 developed measures of preference for negative social feedback and social self-esteem, and provided evidence of their incremental validity in a college sample. Study 2 found that these two variables are not strongly related to fears of evaluation, are relatively unaffected by a treatment that targets such fears, and predict residual social anxiety following treatment. Overall, these studies provide preliminary evidence for a self-verification model of social anxiety.

  14. Diode step stress program for JANTX1N5615

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The effect of power/temperature step stress when applied to the switching diode JANTX1N5615 manufactured by Semtech and Micro semiconductor was examined. A total of 48 samples from each manufacturer were submitted to the process. In addition, two control sample units were maintained for verification of the electrical parametric testing. All test samples were subjected to the electrical tests after completing the prior power/temperature step stress point. Results are presented.

  15. Results of the performance verification of the CoaguChek XS system.

    PubMed

    Plesch, W; Wolf, T; Breitenbeck, N; Dikkeschei, L D; Cervero, A; Perez, P L; van den Besselaar, A M H P

    2008-01-01

    This is the first paper reporting a performance verification study of a point-of-care (POC) monitor for prothrombin time (PT) testing according to the requirements given in chapter 8 of the International Organization for Standardization (ISO) 17593:2007 standard "Clinical laboratory testing and in vitro medical devices - Requirements for in vitro monitoring systems for self-testing of oral anticoagulant therapy". The monitor under investigation was the new CoaguChek XS system which is designed for use in patient self testing. Its detection principle is based on the amperometric measurement of the thrombin activity generated by starting the coagulation cascade using a recombinant human thromboplastin. The system performance verification study was performed at four study centers using venous and capillary blood samples on two test strip lots. Laboratory testing was performed from corresponding frozen plasma samples with six commercial thromboplastins. Samples from 73 normal donors and 297 patients on oral anticoagulation therapy were collected. Results were assessed using a refined data set of 260 subjects according to the ISO 17593:2007 standard. Each of the two test strip lots met the acceptance criteria of ISO 17593:2007 versus all thromboplastins (bias -0.19 to 0.18 INR; >97% of data within accuracy limits). The coefficient of variation for imprecision of the PT determinations in INR ranged from 2.0% to 3.2% in venous, and from 2.9% to 4.0% in capillary blood testing. Capillary versus venous INR data showed agreement of results with regression lines equal to the line of identity. The new system demonstrated a high level of trueness and accuracy, and low imprecision in INR testing. It can be concluded that the CoaguChek XS system complies with the requirements in chapter 8 of the ISO standard 17593:2007.

  16. Numerical verification of three point bending experiment of magnetorheological elastomer (MRE) in magnetic field

    NASA Astrophysics Data System (ADS)

    Miedzinska, Danuta; Boczkowska, Anna; Zubko, Konrad

    2010-07-01

    In the article a method of numerical verification of experimental results for magnetorheological elastomer samples (MRE) is presented. The samples were shaped into cylinders with diameter of 8 mm and height of 20 mm with various carbonyl iron volume shares (1,5%, 11,5% and 33%). The diameter of soft ferromagnetic substance particles ranged from 6 to 9 μm. During the experiment, initially bended samples were exposed to the magnetic field with intensity levels at 0,1T, 0,3T, 0,5T, 0,7 and 1T. The reaction of the sample to the field action was measured as a displacement of a specimen. Numerical calculation was carried out with the MSC Patran/Marc computer code. For the purpose of numerical analysis the orthotropic material model with the material properties of magnetorheological elastomer along the iron chains, and of the pure elastomer along other directions, was applied. The material properties were obtained from the experimental tests. During the numerical analysis, the initial mechanical load resulting from cylinder deflection was set. Then, the equivalent external force, that was set on the basis of analytical calculations of intermolecular reaction within iron chains in the specific magnetic field, was put on the bended sample. Correspondence of such numerical model with results of the experiment was verified. Similar results of the experiments and both theoretical and FEM analysis indicates that macroscopic modeling of magnetorheological elastomer mechanical properties as orthotropic material delivers accurate enough description of the material's behavior.

  17. A Simple Visual Ethanol Biosensor Based on Alcohol Oxidase Immobilized onto Polyaniline Film for Halal Verification of Fermented Beverage Samples

    PubMed Central

    Kuswandi, Bambang; Irmawati, Titi; Hidayat, Moch Amrun; Jayus; Ahmad, Musa

    2014-01-01

    A simple visual ethanol biosensor based on alcohol oxidase (AOX) immobilised onto polyaniline (PANI) film for halal verification of fermented beverage samples is described. This biosensor responds to ethanol via a colour change from green to blue, due to the enzymatic reaction of ethanol that produces acetaldehyde and hydrogen peroxide, when the latter oxidizes the PANI film. The procedure to obtain this biosensor consists of the immobilization of AOX onto PANI film by adsorption. For the immobilisation, an AOX solution is deposited on the PANI film and left at room temperature until dried (30 min). The biosensor was constructed as a dip stick for visual and simple use. The colour changes of the films have been scanned and analysed using image analysis software (i.e., ImageJ) to study the characteristics of the biosensor's response toward ethanol. The biosensor has a linear response in an ethanol concentration range of 0.01%–0.8%, with a correlation coefficient (r) of 0.996. The limit detection of the biosensor was 0.001%, with reproducibility (RSD) of 1.6% and a life time up to seven weeks when stored at 4 °C. The biosensor provides accurate results for ethanol determination in fermented drinks and was in good agreement with the standard method (gas chromatography) results. Thus, the biosensor could be used as a simple visual method for ethanol determination in fermented beverage samples that can be useful for Muslim community for halal verification. PMID:24473284

  18. Galaxy-galaxy lensing in the Dark Energy Survey Science Verification data

    NASA Astrophysics Data System (ADS)

    Clampitt, J.; Sánchez, C.; Kwan, J.; Krause, E.; MacCrann, N.; Park, Y.; Troxel, M. A.; Jain, B.; Rozo, E.; Rykoff, E. S.; Wechsler, R. H.; Blazek, J.; Bonnett, C.; Crocce, M.; Fang, Y.; Gaztanaga, E.; Gruen, D.; Jarvis, M.; Miquel, R.; Prat, J.; Ross, A. J.; Sheldon, E.; Zuntz, J.; Abbott, T. M. C.; Abdalla, F. B.; Armstrong, R.; Becker, M. R.; Benoit-Lévy, A.; Bernstein, G. M.; Bertin, E.; Brooks, D.; Burke, D. L.; Carnero Rosell, A.; Carrasco Kind, M.; Cunha, C. E.; D'Andrea, C. B.; da Costa, L. N.; Desai, S.; Diehl, H. T.; Dietrich, J. P.; Doel, P.; Estrada, J.; Evrard, A. E.; Fausti Neto, A.; Flaugher, B.; Fosalba, P.; Frieman, J.; Gruendl, R. A.; Honscheid, K.; James, D. J.; Kuehn, K.; Kuropatkin, N.; Lahav, O.; Lima, M.; March, M.; Marshall, J. L.; Martini, P.; Melchior, P.; Mohr, J. J.; Nichol, R. C.; Nord, B.; Plazas, A. A.; Romer, A. K.; Sanchez, E.; Scarpine, V.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, R. C.; Soares-Santos, M.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Vikram, V.; Walker, A. R.

    2017-03-01

    We present galaxy-galaxy lensing results from 139 deg2 of Dark Energy Survey (DES) Science Verification (SV) data. Our lens sample consists of red galaxies, known as redMaGiC, which are specifically selected to have a low photometric redshift error and outlier rate. The lensing measurement has a total signal-to-noise ratio of 29 over scales 0.09 < R < 15 Mpc h-1, including all lenses over a wide redshift range 0.2 < z < 0.8. Dividing the lenses into three redshift bins for this constant moving number density sample, we find no evidence for evolution in the halo mass with redshift. We obtain consistent results for the lensing measurement with two independent shear pipelines, NGMIX and IM3SHAPE. We perform a number of null tests on the shear and photometric redshift catalogues and quantify resulting systematic uncertainties. Covariances from jackknife subsamples of the data are validated with a suite of 50 mock surveys. The result and systematic checks in this work provide a critical input for future cosmological and galaxy evolution studies with the DES data and redMaGiC galaxy samples. We fit a halo occupation distribution (HOD) model, and demonstrate that our data constrain the mean halo mass of the lens galaxies, despite strong degeneracies between individual HOD parameters.

  19. Verification of spectrophotometric method for nitrate analysis in water samples

    NASA Astrophysics Data System (ADS)

    Kurniawati, Puji; Gusrianti, Reny; Dwisiwi, Bledug Bernanti; Purbaningtias, Tri Esti; Wiyantoko, Bayu

    2017-12-01

    The aim of this research was to verify the spectrophotometric method to analyze nitrate in water samples using APHA 2012 Section 4500 NO3-B method. The verification parameters used were: linearity, method detection limit, level of quantitation, level of linearity, accuracy and precision. Linearity was obtained by using 0 to 50 mg/L nitrate standard solution and the correlation coefficient of standard calibration linear regression equation was 0.9981. The method detection limit (MDL) was defined as 0,1294 mg/L and limit of quantitation (LOQ) was 0,4117 mg/L. The result of a level of linearity (LOL) was 50 mg/L and nitrate concentration 10 to 50 mg/L was linear with a level of confidence was 99%. The accuracy was determined through recovery value was 109.1907%. The precision value was observed using % relative standard deviation (%RSD) from repeatability and its result was 1.0886%. The tested performance criteria showed that the methodology was verified under the laboratory conditions.

  20. Verification of hypergraph states

    NASA Astrophysics Data System (ADS)

    Morimae, Tomoyuki; Takeuchi, Yuki; Hayashi, Masahito

    2017-12-01

    Hypergraph states are generalizations of graph states where controlled-Z gates on edges are replaced with generalized controlled-Z gates on hyperedges. Hypergraph states have several advantages over graph states. For example, certain hypergraph states, such as the Union Jack states, are universal resource states for measurement-based quantum computing with only Pauli measurements, while graph state measurement-based quantum computing needs non-Clifford basis measurements. Furthermore, it is impossible to classically efficiently sample measurement results on hypergraph states unless the polynomial hierarchy collapses to the third level. Although several protocols have been proposed to verify graph states with only sequential single-qubit Pauli measurements, there was no verification method for hypergraph states. In this paper, we propose a method for verifying a certain class of hypergraph states with only sequential single-qubit Pauli measurements. Importantly, no i.i.d. property of samples is assumed in our protocol: any artificial entanglement among samples cannot fool the verifier. As applications of our protocol, we consider verified blind quantum computing with hypergraph states, and quantum computational supremacy demonstrations with hypergraph states.

  1. JacketSE: An Offshore Wind Turbine Jacket Sizing Tool; Theory Manual and Sample Usage with Preliminary Validation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Damiani, Rick

    This manual summarizes the theory and preliminary verifications of the JacketSE module, which is an offshore jacket sizing tool that is part of the Wind-Plant Integrated System Design & Engineering Model toolbox. JacketSE is based on a finite-element formulation and on user-prescribed inputs and design standards' criteria (constraints). The physics are highly simplified, with a primary focus on satisfying ultimate limit states and modal performance requirements. Preliminary validation work included comparing industry data and verification against ANSYS, a commercial finite-element analysis package. The results are encouraging, and future improvements to the code are recommended in this manual.

  2. 9 CFR 417.8 - Agency verification.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ....8 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS § 417.8 Agency verification. FSIS will verify the... plan or system; (f) Direct observation or measurement at a CCP; (g) Sample collection and analysis to...

  3. 9 CFR 417.8 - Agency verification.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ....8 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS § 417.8 Agency verification. FSIS will verify the... plan or system; (f) Direct observation or measurement at a CCP; (g) Sample collection and analysis to...

  4. 9 CFR 417.8 - Agency verification.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ....8 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS § 417.8 Agency verification. FSIS will verify the... plan or system; (f) Direct observation or measurement at a CCP; (g) Sample collection and analysis to...

  5. 9 CFR 417.8 - Agency verification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....8 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS § 417.8 Agency verification. FSIS will verify the... plan or system; (f) Direct observation or measurement at a CCP; (g) Sample collection and analysis to...

  6. 9 CFR 417.8 - Agency verification.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ....8 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS § 417.8 Agency verification. FSIS will verify the... plan or system; (f) Direct observation or measurement at a CCP; (g) Sample collection and analysis to...

  7. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - BAGHOUSE FILTRATION PRODUCTS - INSPEC FIBRES 5512BRF FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) pilot of the Environmental Technology Verification (ETV) Program. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of th...

  8. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - BAGHOUSE FILTRATION PRODUCTS - MENARDI-CRISWELL 50-504 FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) pilot of the Environmental Technology Verification (ETV) Program. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of th...

  9. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, GROUNDWATER SAMPLING TECHNOLOGIES, GEOPROBE INC., PNEUMATIC BLADDER PUMP GW 1400 SERIES

    EPA Science Inventory

    The U.S. Environmental Protection Agency (EPA) design efficient processes for conducting has created the Environmental Technology perfofl1lance tests of innovative technologies. Verification Program (E TV) to facilitate the deployment of innovative or improved environmental techn...

  10. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, GROUNDWATER SAMPLING TECHNOLOGIES, GEOPROBE INC, MECHANICAL BLADDER PUMP MODEL MP470

    EPA Science Inventory

    The U.S. Environmental Protection Agency (EPA) design efficient processes for conducting has created the Environmental Technology perfofl1lance tests of innovative technologies. Verification Program (E TV) to facilitate the deployment of innovative or improved environmental techn...

  11. Letter Report - Verification Survey of Final Grids at the David Witherspoon, Inc. 1630 Site Knoxville, Tennessee

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    P.C. Weaver

    2009-02-17

    Conduct verification surveys of grids at the DWI 1630 Site in Knoxville, Tennessee. The independent verification team (IVT) from ORISE, conducted verification activities in whole and partial grids, as completed by BJC. ORISE site activities included gamma surface scans and soil sampling within 33 grids; G11 through G14; H11 through H15; X14, X15, X19, and X21; J13 through J15 and J17 through J21; K7 through K9 and K13 through K15; L13 through L15; and M14 through M16

  12. International Space Station Requirement Verification for Commercial Visiting Vehicles

    NASA Technical Reports Server (NTRS)

    Garguilo, Dan

    2017-01-01

    The COTS program demonstrated NASA could rely on commercial providers for safe, reliable, and cost-effective cargo delivery to ISS. The ISS Program has developed a streamlined process to safely integrate commercial visiting vehicles and ensure requirements are met Levy a minimum requirement set (down from 1000s to 100s) focusing on the ISS interface and safety, reducing the level of NASA oversight/insight and burden on the commercial Partner. Partners provide a detailed verification and validation plan documenting how they will show they've met NASA requirements. NASA conducts process sampling to ensure that the established verification processes is being followed. NASA participates in joint verification events and analysis for requirements that require both parties verify. Verification compliance is approved by NASA and launch readiness certified at mission readiness reviews.

  13. Photometric redshift analysis in the Dark Energy Survey Science Verification data

    NASA Astrophysics Data System (ADS)

    Sánchez, C.; Carrasco Kind, M.; Lin, H.; Miquel, R.; Abdalla, F. B.; Amara, A.; Banerji, M.; Bonnett, C.; Brunner, R.; Capozzi, D.; Carnero, A.; Castander, F. J.; da Costa, L. A. N.; Cunha, C.; Fausti, A.; Gerdes, D.; Greisel, N.; Gschwend, J.; Hartley, W.; Jouvel, S.; Lahav, O.; Lima, M.; Maia, M. A. G.; Martí, P.; Ogando, R. L. C.; Ostrovski, F.; Pellegrini, P.; Rau, M. M.; Sadeh, I.; Seitz, S.; Sevilla-Noarbe, I.; Sypniewski, A.; de Vicente, J.; Abbot, T.; Allam, S. S.; Atlee, D.; Bernstein, G.; Bernstein, J. P.; Buckley-Geer, E.; Burke, D.; Childress, M. J.; Davis, T.; DePoy, D. L.; Dey, A.; Desai, S.; Diehl, H. T.; Doel, P.; Estrada, J.; Evrard, A.; Fernández, E.; Finley, D.; Flaugher, B.; Frieman, J.; Gaztanaga, E.; Glazebrook, K.; Honscheid, K.; Kim, A.; Kuehn, K.; Kuropatkin, N.; Lidman, C.; Makler, M.; Marshall, J. L.; Nichol, R. C.; Roodman, A.; Sánchez, E.; Santiago, B. X.; Sako, M.; Scalzo, R.; Smith, R. C.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Tucker, D. L.; Uddin, S. A.; Valdés, F.; Walker, A.; Yuan, F.; Zuntz, J.

    2014-12-01

    We present results from a study of the photometric redshift performance of the Dark Energy Survey (DES), using the early data from a Science Verification period of observations in late 2012 and early 2013 that provided science-quality images for almost 200 sq. deg. at the nominal depth of the survey. We assess the photometric redshift (photo-z) performance using about 15 000 galaxies with spectroscopic redshifts available from other surveys. These galaxies are used, in different configurations, as a calibration sample, and photo-z's are obtained and studied using most of the existing photo-z codes. A weighting method in a multidimensional colour-magnitude space is applied to the spectroscopic sample in order to evaluate the photo-z performance with sets that mimic the full DES photometric sample, which is on average significantly deeper than the calibration sample due to the limited depth of spectroscopic surveys. Empirical photo-z methods using, for instance, artificial neural networks or random forests, yield the best performance in the tests, achieving core photo-z resolutions σ68 ˜ 0.08. Moreover, the results from most of the codes, including template-fitting methods, comfortably meet the DES requirements on photo-z performance, therefore, providing an excellent precedent for future DES data sets.

  14. Photometric redshift analysis in the Dark Energy Survey Science Verification data

    DOE PAGES

    Sanchez, C.; Carrasco Kind, M.; Lin, H.; ...

    2014-10-09

    In this study, we present results from a study of the photometric redshift performance of the Dark Energy Survey (DES), using the early data from a Science Verification period of observations in late 2012 and early 2013 that provided science-quality images for almost 200 sq. deg. at the nominal depth of the survey. We assess the photometric redshift (photo-z) performance using about 15 000 galaxies with spectroscopic redshifts available from other surveys. These galaxies are used, in different configurations, as a calibration sample, and photo-z's are obtained and studied using most of the existing photo-z codes. A weighting method inmore » a multidimensional colour–magnitude space is applied to the spectroscopic sample in order to evaluate the photo-z performance with sets that mimic the full DES photometric sample, which is on average significantly deeper than the calibration sample due to the limited depth of spectroscopic surveys. In addition, empirical photo-z methods using, for instance, artificial neural networks or random forests, yield the best performance in the tests, achieving core photo-z resolutions σ68 ~ 0.08. Moreover, the results from most of the codes, including template-fitting methods, comfortably meet the DES requirements on photo-z performance, therefore, providing an excellent precedent for future DES data sets.« less

  15. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - BAGHOUSE FILTRATION PRODUCTS - AIR PURATOR CORPORATION HUYGLAS 1405M FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) pilot of the Environmental Technology Verification (ETV) Program. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of th...

  16. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - BAGHOUSE FILTRATION PRODUCTS - BHA GROUP, INC. QG061 FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) pilot of the Environmental Technology Verification (ETV) Program. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of th...

  17. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - BAGHOUSE FILTRATION PRODUCTS - STANDARD FILTER CORPORATION PE16ZU FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) pilot of the Environmental Technology Verification (ETV) Program. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of th...

  18. Remaining Sites Verification Package for the 1607-B2 Septic System and 100-B-14:2 Sanitary Sewer System, Waste Site Reclassification Form 2006-055

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    L. M. Dittmer

    The 1607-B2 waste site is a former septic system associated with various 100-B facilities, including the 105-B, 108-B, 115-B/C, and 185/190-B buildings. The site was evaluated based on confirmatory results for feeder lines within the 100-B-14:2 subsite and determined to require remediation. The 1607-B2 waste site has been remediated to achieve the remedial action objectives specified in the Remaining Sites ROD. The results of verification sampling show that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also demonstrate that residual contaminant concentrations are protective of groundwater and themore » Columbia River.« less

  19. Sampling and Analysis Plan for Verification Sampling of LANL-Derived Residual Radionuclides in Soils within Tract A-18-2 for Land Conveyance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ruedig, Elizabeth

    Public Law 105-119 directs the U.S. Department of Energy (DOE) to convey or transfer parcels of land to the Incorporated County of Los Alamos or their designees and to the Department of Interior, Bureau of Indian Affairs, in trust for the Pueblo de San Ildefonso. Los Alamos National Security is tasked to support DOE in conveyance and/or transfer of identified land parcels no later than September 2022. Under DOE Order 458.1, Radiation Protection of the Public and the Environment (O458.1, 2013) and Los Alamos National Laboratory (LANL or the Laboratory) implementing Policy 412 (P412, 2014), real property with the potentialmore » to contain residual radioactive material must meet the criteria for clearance and release to the public. This Sampling and Analysis Plan (SAP) is a second investigation of Tract A-18-2 for the purpose of verifying the previous sampling results (LANL 2017). This sample plan requires 18 projectspecific soil samples for use in radiological clearance decisions consistent with LANL Procedure ENV-ES-TP-238 (2015a) and guidance in the Multi-Agency Radiation Survey and Site Investigation Manual (MARSSIM, 2000). The sampling work will be conducted by LANL, and samples will be evaluated by a LANL-contracted independent lab. However, there will be federal review (verification) of all steps of the sampling process.« less

  20. Verifying Sediment Fingerprinting Results with Known Mixtures

    NASA Astrophysics Data System (ADS)

    Gellis, A.; Gorman-Sanisaca, L.; Cashman, M. J.

    2017-12-01

    Sediment fingerprinting is a widely used approach to determine the specific sources of fluvial sediment within a watershed. It relies on the principle that potential sediment sources can be identified using a set of chemical tracers (or fingerprints), and comparison of these source fingerprints with fluvial (target) sediment allows for source apportionment of the fluvial sediment. There are numerous source classifications, fingerprints, and statistical approaches used in the literature to apportion sources of sediment. However, few of these studies have sought to test the method by creating controls on the ratio of sources in the target sediment. Without a controlled environment for inputs and outputs, such verification of results is ambiguous. Here, we generated artificial mixtures of source sediment from an agricultural/forested watershed in Virginia, USA (Smith Creek, 246 km2) to verify the apportionment results. Target samples were established from known mixtures of the four major sediment sources in the watershed (forest, pasture, cropland, and streambanks). The target samples were sieved to less than 63 microns and analyzed for elemental and isotopic chemistry. The target samples and source samples were run through the Sediment Source Assessment Tool (Sed_SAT) to verify if the statistical operations provided the correct apportionment. Sed_SAT uses a multivariate parametric approach to identify the minimum suite of fingerprints that discriminate the source areas and applies these fingerprints through an unmixng model to apportion sediment. The results of this sediment fingerprinting verification experiment will be presented in this session.

  1. 78 FR 5409 - Ongoing Equivalence Verifications of Foreign Food Regulatory Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... of data shared. Finally, with respect to POE re-inspections, NACMPI recommended the targeting of high-risk product and high-risk imports for sampling and other verification activities during reinspection... authority; the availability of contingency plans in the country for containing and mitigating the effects of...

  2. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, BAGHOUSE FILTRATION PRODUCTS, BHA GROUP, INC., QP131 FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) Verification Center. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of the size of those particles equal to and smalle...

  3. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, BAGHOUSE FILTRATION PRODUCTS, W.L. GORE & ASSOCIATES, INC., L4427 FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) Verification Center. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of the size of those particles equal to and smalle...

  4. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - BAGHOUSE FILTRATION PRODUCTS - W.L. GORE & ASSOCIATES, INC. L4347 FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) pilot of the Environmental Technology Verification (ETV) Program. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of th...

  5. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, BAGHOUSE FILTRATION PRODUCTS, POLYMER GROUP, INC., DURAPEX PET FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) Verification Center. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of the size of those particles equal to and smalle...

  6. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - BAGHOUSE FILTRATION PRODUCTS - ALBANY INTERNATIONAL CORP. INDUSTRIAL PROCESS TECHNOLOGIES PRIMATEX PLUS I FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) pilot of the Environmental Technology Verification (ETV) Program. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of th...

  7. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT: BAGHOUSE FILTRATION PRODUCTS, W.L. GORE & ASSOCIATES, INC. LYSB3 FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) Verification Center. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of the size for particles equal to or smaller than...

  8. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, BAGHOUSE FILTRATION PRODUCTS, TETRATEC PTFE PRODUCTS, TETRATEX 6212 FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) Verification Center. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of the size of those particles equal to and smalle...

  9. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - BAGHOUSE FILTRATION PRODUCTS - BASF CORPORATION AX/BA-14/9-SAXP FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) pilot of the Environmental Technology Verification (ETV) Program. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of th...

  10. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT: BAGHOUSE FILTRATION PRODUCTS, BWF AMERICA, INC. GRADE 700 MPS POLYESTER FELT FILTER SAMPLE

    EPA Science Inventory

    Baghouse filtration products (BFPs) were evaluated by the Air Pollution Control Technology (APCT) Verification Center. The performance factor verified was the mean outlet particle concentration for the filter fabric as a function of the size for particles equal to or smaller than...

  11. Weak lensing magnification in the Dark Energy Survey Science Verification data

    NASA Astrophysics Data System (ADS)

    Garcia-Fernandez, M.; Sanchez, E.; Sevilla-Noarbe, I.; Suchyta, E.; Huff, E. M.; Gaztanaga, E.; Aleksić, J.; Ponce, R.; Castander, F. J.; Hoyle, B.; Abbott, T. M. C.; Abdalla, F. B.; Allam, S.; Annis, J.; Benoit-Lévy, A.; Bernstein, G. M.; Bertin, E.; Brooks, D.; Buckley-Geer, E.; Burke, D. L.; Carnero Rosell, A.; Carrasco Kind, M.; Carretero, J.; Crocce, M.; Cunha, C. E.; D'Andrea, C. B.; da Costa, L. N.; DePoy, D. L.; Desai, S.; Diehl, H. T.; Eifler, T. F.; Evrard, A. E.; Fernandez, E.; Flaugher, B.; Fosalba, P.; Frieman, J.; García-Bellido, J.; Gerdes, D. W.; Giannantonio, T.; Gruen, D.; Gruendl, R. A.; Gschwend, J.; Gutierrez, G.; James, D. J.; Jarvis, M.; Kirk, D.; Krause, E.; Kuehn, K.; Kuropatkin, N.; Lahav, O.; Lima, M.; MacCrann, N.; Maia, M. A. G.; March, M.; Marshall, J. L.; Melchior, P.; Miquel, R.; Mohr, J. J.; Plazas, A. A.; Romer, A. K.; Roodman, A.; Rykoff, E. S.; Scarpine, V.; Schubnell, M.; Smith, R. C.; Soares-Santos, M.; Sobreira, F.; Tarle, G.; Thomas, D.; Walker, A. R.; Wester, W.; DES Collaboration

    2018-05-01

    In this paper, the effect of weak lensing magnification on galaxy number counts is studied by cross-correlating the positions of two galaxy samples, separated by redshift, using the Dark Energy Survey Science Verification data set. This analysis is carried out for galaxies that are selected only by its photometric redshift. An extensive analysis of the systematic effects, using new methods based on simulations is performed, including a Monte Carlo sampling of the selection function of the survey.

  12. Biomarker Discovery and Verification of Esophageal Squamous Cell Carcinoma Using Integration of SWATH/MRM.

    PubMed

    Hou, Guixue; Lou, Xiaomin; Sun, Yulin; Xu, Shaohang; Zi, Jin; Wang, Quanhui; Zhou, Baojin; Han, Bo; Wu, Lin; Zhao, Xiaohang; Lin, Liang; Liu, Siqi

    2015-09-04

    We propose an efficient integration of SWATH with MRM for biomarker discovery and verification when the corresponding ion library is well established. We strictly controlled the false positive rate associated with SWATH MS signals and carefully selected the target peptides coupled with SWATH and MRM. We collected 10 samples of esophageal squamous cell carcinoma (ESCC) tissues paired with tumors and adjacent regions and quantified 1758 unique proteins with FDR 1% at protein level using SWATH, in which 467 proteins were abundance-dependent with ESCC. After carefully evaluating the SWATH MS signals of the up-regulated proteins, we selected 120 proteins for MRM verification. MRM analysis of the pooled and individual esophageal tissues resulted in 116 proteins that exhibited similar abundance response modes to ESCC that were acquired with SWATH. Because the ESCC-related proteins consisted of a high percentile of secreted proteins, we conducted the MRM assay on patient sera that were collected from pre- and postoperation. Of the 116 target proteins, 42 were identified in the ESCC sera, including 11 with lowered abundances postoperation. Coupling SWATH and MRM is thus feasible and efficient for the discovery and verification of cancer-related protein biomarkers.

  13. INNOVATIVE TECHNOLOGY VERIFICATION REPORT XRF ...

    EPA Pesticide Factsheets

    The Rigaku ZSX Mini II (ZSX Mini II) XRF Services x-ray fluorescence (XRF) analyzer was demon-strated under the U.S. Environmental Protection Agency (EPA) Superfund Innovative Technology Evaluation (SITE) Program. The field portion of the demonstration was conducted in January 2005 at the Kennedy Athletic, Recreational and Social Park (KARS) at Kennedy Space Center on Merritt Island, Florida. The demonstration was designed to collect reliable performance and cost data for the ZSX Mini II analyzer and seven other commercially available XRF instruments for measuring trace elements in soil and sediment. The performance and cost data were evaluated to document the relative performance of each XRF instrument. This innovative technology verification report describes the objectives and the results of that evaluation and serves to verify the performance and cost of the ZSX Mini II analyzer. Separate reports have been prepared for the other XRF instruments that were evaluated as part of the demonstration. The objectives of the evaluation included determining each XRF instrument’s accuracy, precision, sample throughput, and tendency for matrix effects. To fulfill these objectives, the field demonstration incorporated the analysis of 326 prepared samples of soil and sediment that contained 13 target elements. The prepared samples included blends of environmental samples from nine different sample collection sites as well as spiked samples with certified element con

  14. INNOVATIVE TECHNOLOGY VERIFICATION REPORT XRF ...

    EPA Pesticide Factsheets

    The Rontec PicoTAX x-ray fluorescence (XRF) analyzer was demonstrated under the U.S. Environmental Protection Agency (EPA) Superfund Innovative Technology Evaluation (SITE) Program. The field portion of the demonstration was conducted in January 2005 at the Kennedy Athletic, Recreational and Social Park (KARS) at Kennedy Space Center on Merritt Island, Florida. The demonstration was designed to collect reliable performance and cost data for the PicoTAX analyzer and seven other commercially available XRF instruments for measuring trace elements in soil and sediment. The performance and cost data were evaluated to document the relative performance of each XRF instrument. This innovative technology verification report describes the objectives and the results of that evaluation and serves to verify the performance and cost of the PicoTAX analyzer. Separate reports have been prepared for the other XRF instruments that were evaluated as part of the demonstration. The objectives of the evaluation included determining each XRF instrument’s accuracy, precision, sample throughput, and tendency for matrix effects. To fulfill these objectives, the field demonstration incorporated the analysis of 326 prepared samples of soil and sediment that contained 13 target elements. The prepared samples included blends of environmental samples from nine different sample collection sites as well as spiked samples with certified element concentrations. Accuracy was assessed by c

  15. INNOVATIVE TECHNOLOGY VERIFICATION REPORT XRF ...

    EPA Pesticide Factsheets

    The Niton XLt 700 Series (XLt) XRF Services x-ray fluorescence (XRF) analyzer was demonstrated under the U.S. Environmental Protection Agency (EPA) Superfund Innovative Technology Evaluation (SITE) Program. The field portion of the demonstration was conducted in January 2005 at the Kennedy Athletic, Recreational and Social Park (KARS) at Kennedy Space Center on Merritt Island, Florida. The demonstration was designed to collect reliable performance and cost data for the XLt analyzer and seven other commercially available XRF instruments for measuring trace elements in soil and sediment. The performance and cost data were evaluated to document the relative performance of each XRF instrument. This innovative technology verification report describes the objectives and the results of that evaluation and serves to verify the performance and cost of the XLt analyzer. Separate reports have been prepared for the other XRF instruments that were evaluated as part of the demonstration. The objectives of the evaluation included determining each XRF instrument’s accuracy, precision, sample throughput, and tendency for matrix effects. To fulfill these objectives, the field demonstration incorporated the analysis of 326 prepared samples of soil and sediment that contained 13 target elements. The prepared samples included blends of environmental samples from nine different sample collection sites as well as spiked samples with certified element concentrations. Accuracy

  16. INNOVATIVE TECHNOLOGY VERIFICATION REPORT XRF ...

    EPA Pesticide Factsheets

    The Oxford ED2000 x-ray fluorescence (XRF) analyzer was demonstrated under the U.S. Environmental Protection Agency (EPA) Superfund Innovative Technology Evaluation (SITE) Program. The field portion of the demonstration was conducted in January 2005 at the Kennedy Athletic, Recreational and Social Park (KARS) at Kennedy Space Center on Merritt Island, Florida. The demonstration was designed to collect reliable performance and cost data for the ED2000 analyzer and seven other commercially available XRF instruments for measuring trace elements in soil and sediment. The performance and cost data were evaluated to document the relative performance of each XRF instrument. This innovative technology verification report describes the objectives and the results of that evaluation and serves to verify the performance and cost of the ED2000 analyzer. Separate reports have been prepared for the other XRF instruments that were evaluated as part of the demonstration. The objectives of the evaluation included determining each XRF instrument’s accuracy, precision, sample throughput, and tendency for matrix effects. To fulfill these objectives, the field demonstration incorporated the analysis of 326 prepared samples of soil and sediment that contained 13 target elements. The prepared samples included blends of environmental samples from nine different sample collection sites as well as spiked samples with certified element concentrations. Accuracy was assessed by com

  17. INNOVATIVE TECHNOLOGY VERIFICATION REPORT XRF ...

    EPA Pesticide Factsheets

    The Innov-X XT400 Series (XT400) x-ray fluorescence (XRF) analyzer was demonstrated under the U.S. Environmental Protection Agency (EPA) Superfund Innovative Technology Evaluation (SITE) Program. The field portion of the demonstration was conducted in January 2005 at the Kennedy Athletic, Recreational and Social Park (KARS) at Kennedy Space Center on Merritt Island, Florida. The demonstration was designed to collect reliable performance and cost data for the XT400 analyzer and seven other commercially available XRF instruments for measuring trace elements in soil and sediment. The performance and cost data were evaluated to document the relative performance of each XRF instrument. This innovative technology verification report describes the objectives and the results of that evaluation and serves to verify the performance and cost of the XT400 analyzer. Separate reports have been prepared for the other XRF instruments that were evaluated as part of the demonstration. The objectives of the evaluation included determining each XRF instrument’s accuracy, precision, sample throughput, and tendency for matrix effects. To fulfill these objectives, the field demonstration incorporated the analysis of 326 prepared samples of soil and sediment that contained 13 target elements. The prepared samples included blends of environmental samples from nine different sample collection sites as well as spiked samples with certified element concentrations. Accuracy was as

  18. INTERIM REPORT--INDEPENDENT VERIFICATION SURVEY OF SECTION 3, SURVEY UNITS 1, 4 AND 5 EXCAVATED SURFACES, WHITTAKER CORPORATION, REYNOLDS INDUSTRIAL PARK, TRANSFER, PENNSYLVANIA DCN: 5002-SR-04-0"

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    ADAMS, WADE C

    At Pennsylvania Department of Environmental Protection's request, ORAU's IEAV program conducted verification surveys on the excavated surfaces of Section 3, SUs 1, 4, and 5 at the Whittaker site on March 13 and 14, 2013. The survey activities included visual inspections, gamma radiation surface scans, gamma activity measurements, and soil sampling activities. Verification activities also included the review and assessment of the licensee's project documentation and methodologies. Surface scans identified four areas of elevated direct gamma radiation distinguishable from background; one area within SUs 1 and 4 and two areas within SU5. One area within SU5 was remediated by removingmore » a golf ball size piece of slag while ORAU staff was onsite. With the exception of the golf ball size piece of slag within SU5, a review of the ESL Section 3 EXS data packages for SUs 1, 4, and 5 indicated that these locations of elevated gamma radiation were also identified by the ESL gamma scans and that ESL personnel performed additional investigations and soil sampling within these areas. The investigative results indicated that the areas met the release criteria.« less

  19. [Verification of ballast water exchange for international ships anchored in Xiamen Port by CDOM tracer].

    PubMed

    Li, Chao; Zhang, Yan-po; Guo, Wei-dong; Zhu, Yue; Xu, Jing; Deng, Xun

    2010-09-01

    Fluorescence excitation-emission matrix (EEM) and absorption spectroscopy were applied to study the optical properties of 29 CDOM samples collected from different ballast tanks of nine international route vessels anchored in Xiamen Port between October 2007 and April 2008. The purpose was to examine the feasibility of these spectral properties as a tracer to verify if these vessels follow the mid-ocean ballast water exchange (BWE) regulation. Using parallel factor analysis, four fluorescent components were identified, including two humic-like components (C1: 245, 300/386 nm; C2: 250, 345/458 nm) and two protein-like components (C3: 220, 275/306 nm; C4: 235, 290/345 nm), of which C2 component was the suitable fluorescence verification indicator. The vertical distribution of all fluorescent components in ballast tank was nearly similar indicating that profile-mixing sampling was preferable. Combined use of C2 component, spectral slope ratio (SR) of absorption spectroscopy and salinity may provide reasonable verification if BWE carried out by these nine ships. The results suggested that the combined use of multiple parameters (fluorescence, absorption and salinity) would be much reliable to determine the origin of ballast water, and to provide the technical guarantee for fast examination of ballast water exchange in Chinese ports.

  20. Galaxy-galaxy lensing in the Dark Energy Survey Science Verification data

    DOE PAGES

    Clampitt, J.; S?nchez, C.; Kwan, J.; ...

    2016-11-22

    We present galaxy-galaxy lensing results from 139 square degrees of Dark Energy Survey (DES) Science Verification (SV) data. Our lens sample consists of red galaxies, known as redMaGiC, which are specifically selected to have a low photometric redshift error and outlier rate. The lensing measurement has a total signal-to-noise of 29 over scales $0.09 < R < 15$ Mpc/$h$, including all lenses over a wide redshift range $0.2 < z < 0.8$. Dividing the lenses into three redshift bins for this constant moving number density sample, we find no evidence for evolution in the halo mass with redshift. We obtainmore » consistent results for the lensing measurement with two independent shear pipelines, ngmix and im3shape. We perform a number of null tests on the shear and photometric redshift catalogs and quantify resulting systematic uncertainties. Covariances from jackknife subsamples of the data are validated with a suite of 50 mock surveys. The results and systematics checks in this work provide a critical input for future cosmological and galaxy evolution studies with the DES data and redMaGiC galaxy samples. We fit a Halo Occupation Distribution (HOD) model, and demonstrate that our data constrains the mean halo mass of the lens galaxies, despite strong degeneracies between individual HOD parameters.« less

  1. Galaxy-galaxy lensing in the Dark Energy Survey Science Verification data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Clampitt, J.; S?nchez, C.; Kwan, J.

    We present galaxy-galaxy lensing results from 139 square degrees of Dark Energy Survey (DES) Science Verification (SV) data. Our lens sample consists of red galaxies, known as redMaGiC, which are specifically selected to have a low photometric redshift error and outlier rate. The lensing measurement has a total signal-to-noise of 29 over scales $0.09 < R < 15$ Mpc/$h$, including all lenses over a wide redshift range $0.2 < z < 0.8$. Dividing the lenses into three redshift bins for this constant moving number density sample, we find no evidence for evolution in the halo mass with redshift. We obtainmore » consistent results for the lensing measurement with two independent shear pipelines, ngmix and im3shape. We perform a number of null tests on the shear and photometric redshift catalogs and quantify resulting systematic uncertainties. Covariances from jackknife subsamples of the data are validated with a suite of 50 mock surveys. The results and systematics checks in this work provide a critical input for future cosmological and galaxy evolution studies with the DES data and redMaGiC galaxy samples. We fit a Halo Occupation Distribution (HOD) model, and demonstrate that our data constrains the mean halo mass of the lens galaxies, despite strong degeneracies between individual HOD parameters.« less

  2. 40 CFR 1065.308 - Continuous gas analyzer system-response and updating-recording verification-for gas analyzers not...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... which you sample and record gas-analyzer concentrations. (b) Measurement principles. This test verifies... appropriate frequency to prevent loss of information. This test also verifies that the measurement system... instructions. Adjust the measurement system as needed to optimize performance. Run this verification with the...

  3. 40 CFR 1065.390 - PM balance verifications and weighing process verification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... days before weighing any filter. (2) Zero and span the balance within 12 h before weighing any filter. (3) Verify that the mass determination of reference filters before and after a filter weighing... reference PM sample media (e.g., filters) before and after a weighing session. A weighing session may be as...

  4. 40 CFR 1065.390 - PM balance verifications and weighing process verification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... days before weighing any filter. (2) Zero and span the balance within 12 h before weighing any filter. (3) Verify that the mass determination of reference filters before and after a filter weighing... reference PM sample media (e.g., filters) before and after a weighing session. A weighing session may be as...

  5. 40 CFR 1065.390 - PM balance verifications and weighing process verification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... days before weighing any filter. (2) Zero and span the balance within 12 h before weighing any filter. (3) Verify that the mass determination of reference filters before and after a filter weighing... reference PM sample media (e.g., filters) before and after a weighing session. A weighing session may be as...

  6. 40 CFR 1065.390 - PM balance verifications and weighing process verification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... days before weighing any filter. (2) Zero and span the balance within 12 h before weighing any filter. (3) Verify that the mass determination of reference filters before and after a filter weighing... reference PM sample media (e.g., filters) before and after a weighing session. A weighing session may be as...

  7. 40 CFR 1065.390 - PM balance verifications and weighing process verification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... days before weighing any filter. (2) Zero and span the balance within 12 h before weighing any filter. (3) Verify that the mass determination of reference filters before and after a filter weighing... weighing session by weighing reference PM sample media (e.g., filters) before and after a weighing session...

  8. Clean assembly and integration techniques for the Hubble Space Telescope High Fidelity Mechanical Simulator

    NASA Technical Reports Server (NTRS)

    Hughes, David W.; Hedgeland, Randy J.

    1994-01-01

    A mechanical simulator of the Hubble Space Telescope (HST) Aft Shroud was built to perform verification testing of the Servicing Mission Scientific Instruments (SI's) and to provide a facility for astronaut training. All assembly, integration, and test activities occurred under the guidance of a contamination control plan, and all work was reviewed by a contamination engineer prior to implementation. An integrated approach was followed in which materials selection, manufacturing, assembly, subsystem integration, and end product use were considered and controlled to ensure that the use of the High Fidelity Mechanical Simulator (HFMS) as a verification tool would not contaminate mission critical hardware. Surfaces were cleaned throughout manufacturing, assembly, and integration, and reverification was performed following major activities. Direct surface sampling was the preferred method of verification, but access and material constraints led to the use of indirect methods as well. Although surface geometries and coatings often made contamination verification difficult, final contamination sampling and monitoring demonstrated the ability to maintain a class M5.5 environment with surface levels less than 400B inside the HFMS.

  9. Empirical insights and considerations for the OBT inter-laboratory comparison of environmental samples.

    PubMed

    Kim, Sang-Bog; Roche, Jennifer

    2013-08-01

    Organically bound tritium (OBT) is an important tritium species that can be measured in most environmental samples, but has only recently been recognized as a species of tritium in these samples. Currently, OBT is not routinely measured by environmental monitoring laboratories around the world. There are no certified reference materials (CRMs) for environmental samples. Thus, quality assurance (QA), or verification of the accuracy of the OBT measurement, is not possible. Alternatively, quality control (QC), or verification of the precision of the OBT measurement, can be achieved. In the past, there have been differences in OBT analysis results between environmental laboratories. A possible reason for the discrepancies may be differences in analytical methods. Therefore, inter-laboratory OBT comparisons among the environmental laboratories are important and would provide a good opportunity for adopting a reference OBT analytical procedure. Due to the analytical issues, only limited information is available on OBT measurement. Previously conducted OBT inter-laboratory practices are reviewed and the findings are described. Based on our experiences, a few considerations were suggested for the international OBT inter-laboratory comparison exercise to be completed in the near future. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

  10. Model Transformation for a System of Systems Dependability Safety Case

    NASA Technical Reports Server (NTRS)

    Murphy, Judy; Driskell, Steve

    2011-01-01

    The presentation reviews the dependability and safety effort of NASA's Independent Verification and Validation Facility. Topics include: safety engineering process, applications to non-space environment, Phase I overview, process creation, sample SRM artifact, Phase I end result, Phase II model transformation, fault management, and applying Phase II to individual projects.

  11. 40 CFR 1065.935 - Emission test sequence for field testing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... verifications in emission calculations. (5) You may periodically condition and analyze batch samples in-situ... drift corrected results in emissions calculations. (6) Unless you weighed PM in-situ, such as by using... engine in-use until the engine coolant, block, or head absolute temperature is within ±10% of its mean...

  12. 40 CFR 1065.935 - Emission test sequence for field testing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... verifications in emission calculations. (5) You may periodically condition and analyze batch samples in-situ... drift corrected results in emissions calculations. (6) Unless you weighed PM in-situ, such as by using... engine in-use until the engine coolant, block, or head absolute temperature is within ±10% of its mean...

  13. 40 CFR 1065.935 - Emission test sequence for field testing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... verifications in emission calculations. (5) You may periodically condition and analyze batch samples in-situ... drift corrected results in emissions calculations. (6) Unless you weighed PM in-situ, such as by using... engine in-use until the engine coolant, block, or head absolute temperature is within ±10% of its mean...

  14. 40 CFR 1065.935 - Emission test sequence for field testing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... verifications in emission calculations. (5) You may periodically condition and analyze batch samples in-situ... drift corrected results in emissions calculations. (6) Unless you weighed PM in-situ, such as by using... engine in-use until the engine coolant, block, or head absolute temperature is within ±10% of its mean...

  15. 40 CFR 1065.935 - Emission test sequence for field testing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... verifications in emission calculations. (5) You may periodically condition and analyze batch samples in-situ... drift corrected results in emissions calculations. (6) Unless you weighed PM in-situ, such as by using... engine in-use until the engine coolant, block, or head absolute temperature is within ±10% of its mean...

  16. Accuracy of self-reported smoking abstinence in clinical trials of hospital-initiated smoking interventions.

    PubMed

    Scheuermann, Taneisha S; Richter, Kimber P; Rigotti, Nancy A; Cummins, Sharon E; Harrington, Kathleen F; Sherman, Scott E; Zhu, Shu-Hong; Tindle, Hilary A; Preacher, Kristopher J

    2017-12-01

    To estimate the prevalence and predictors of failed biochemical verification of self-reported abstinence among participants enrolled in trials of hospital-initiated smoking cessation interventions. Comparison of characteristics between participants who verified and those who failed to verify self-reported abstinence. Multi-site randomized clinical trials conducted between 2010 and 2014 in hospitals throughout the United States. Recently hospitalized smokers who reported tobacco abstinence 6 months post-randomization and provided a saliva sample for verification purposes (n = 822). Outcomes were salivary cotinine-verified smoking abstinence at 10 and 15 ng/ml cut-points. Predictors and correlates included participant demographics and tobacco use; hospital diagnoses and treatment; and study characteristics collected via surveys and electronic medical records. Usable samples were returned by 69.8% of the 1178 eligible trial participants who reported 7-day point prevalence abstinence. The proportion of participants verified as quit was 57.8% [95% confidence interval (CI) = 54.4, 61.2; 10 ng/ml cut-off] or 60.6% (95% CI = 57.2, 63.9; 15 ng/ml). Factors associated independently with verification at 10 ng/ml were education beyond high school education [odds ratio (OR) = 1.51; 95% CI = 1.07, 2.11], continuous abstinence since hospitalization (OR = 2.82; 95% CI = 2.02, 3.94), mailed versus in-person sample (OR = 3.20; 95% CI = 1.96, 5.21) and race. African American participants were less likely to verify abstinence than white participants (OR = 0.64; 95% CI = 0.44, 0.93). Findings were similar for verification at 15 ng/ml. Verification rates did not differ by treatment group. In the United States, high rates (40%) of recently hospitalized smokers enrolled in smoking cessation trials fail biochemical verification of their self-reported abstinence. © 2017 Society for the Study of Addiction.

  17. GC-MS and LC-MS analysis of nerve agents in body fluids: intra-laboratory verification test using spiked plasma and urine samples.

    PubMed

    Koller, Marianne; Becker, Christian; Thiermann, Horst; Worek, Franz

    2010-05-15

    The purpose of this study was to check the applicability of different analytical methods for the identification of unknown nerve agents in human body fluids. Plasma and urine samples were spiked with nerve agents (plasma) or with their metabolites (urine) or were left blank. Seven random samples (35% of all samples) were selected for the verification test. Plasma was worked up for unchanged nerve agents and for regenerated nerve agents after fluoride-induced reactivation of nerve agent-inhibited butyrylcholinesterase. Both extracts were analysed by GC-MS. Metabolites were extracted from plasma and urine, respectively, and were analysed by LC-MS. The urinary metabolites and two blank samples could be identified without further measurements, plasma metabolites and blanks were identified in six of seven samples. The analysis of unchanged nerve agent provided five agents/blanks and the sixth agent after further investigation. The determination of the regenerated agents also provided only five clear findings during the first screening because of a rather noisy baseline. Therefore, the sample preparation was extended by a size exclusion step performed before addition of fluoride which visibly reduced baseline noise and thus improved identification of the two missing agents. The test clearly showed that verification should be performed by analysing more than one biomarker to ensure identification of the agent(s). Copyright (c) 2010 Elsevier B.V. All rights reserved.

  18. Image Guided Radiation Therapy (IGRT) Practice Patterns and IGRT's Impact on Workflow and Treatment Planning: Results From a National Survey of American Society for Radiation Oncology Members

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nabavizadeh, Nima, E-mail: nabaviza@ohsu.edu; Elliott, David A.; Chen, Yiyi

    Purpose: To survey image guided radiation therapy (IGRT) practice patterns, as well as IGRT's impact on clinical workflow and planning treatment volumes (PTVs). Methods and Materials: A sample of 5979 treatment site–specific surveys was e-mailed to the membership of the American Society for Radiation Oncology (ASTRO), with questions pertaining to IGRT modality/frequency, PTV expansions, method of image verification, and perceived utility/value of IGRT. On-line image verification was defined as images obtained and reviewed by the physician before treatment. Off-line image verification was defined as images obtained before treatment and then reviewed by the physician before the next treatment. Results: Of 601 evaluablemore » responses, 95% reported IGRT capabilities other than portal imaging. The majority (92%) used volumetric imaging (cone-beam CT [CBCT] or megavoltage CT), with volumetric imaging being the most commonly used modality for all sites except breast. The majority of respondents obtained daily CBCTs for head and neck intensity modulated radiation therapy (IMRT), lung 3-dimensional conformal radiation therapy or IMRT, anus or pelvis IMRT, prostate IMRT, and prostatic fossa IMRT. For all sites, on-line image verification was most frequently performed during the first few fractions only. No association was seen between IGRT frequency or CBCT utilization and clinical treatment volume to PTV expansions. Of the 208 academic radiation oncologists who reported working with residents, only 41% reported trainee involvement in IGRT verification processes. Conclusion: Consensus guidelines, further evidence-based approaches for PTV margin selection, and greater resident involvement are needed for standardized use of IGRT practices.« less

  19. Certification of NIST Room Temperature Low-Energy and High-Energy Charpy Verification Specimens

    PubMed Central

    Lucon, Enrico; McCowan, Chris N.; Santoyo, Ray L.

    2015-01-01

    The possibility for NIST to certify Charpy reference specimens for testing at room temperature (21 °C ± 1 °C) instead of −40 °C was investigated by performing 130 room-temperature tests from five low-energy and four high-energy lots of steel on the three master Charpy machines located in Boulder, CO. The statistical analyses performed show that in most cases the variability of results (i.e., the experimental scatter) is reduced when testing at room temperature. For eight out of the nine lots considered, the observed variability was lower at 21 °C than at −40 °C. The results of this study will allow NIST to satisfy requests for room-temperature Charpy verification specimens that have been received from customers for several years: testing at 21 °C removes from the verification process the operator’s skill in transferring the specimen in a timely fashion from the cooling bath to the impact position, and puts the focus back on the machine performance. For NIST, it also reduces the time and cost for certifying new verification lots. For one of the low-energy lots tested with a C-shaped hammer, we experienced two specimens jamming, which yielded unusually high values of absorbed energy. For both specimens, the signs of jamming were clearly visible. For all the low-energy lots investigated, jamming is slightly more likely to occur at 21 °C than at −40 °C, since at room temperature low-energy samples tend to remain in the test area after impact rather than exiting in the opposite direction of the pendulum swing. In the evaluation of a verification set, any jammed specimen should be removed from the analyses. PMID:26958453

  20. Certification of NIST Room Temperature Low-Energy and High-Energy Charpy Verification Specimens.

    PubMed

    Lucon, Enrico; McCowan, Chris N; Santoyo, Ray L

    2015-01-01

    The possibility for NIST to certify Charpy reference specimens for testing at room temperature (21 °C ± 1 °C) instead of -40 °C was investigated by performing 130 room-temperature tests from five low-energy and four high-energy lots of steel on the three master Charpy machines located in Boulder, CO. The statistical analyses performed show that in most cases the variability of results (i.e., the experimental scatter) is reduced when testing at room temperature. For eight out of the nine lots considered, the observed variability was lower at 21 °C than at -40 °C. The results of this study will allow NIST to satisfy requests for room-temperature Charpy verification specimens that have been received from customers for several years: testing at 21 °C removes from the verification process the operator's skill in transferring the specimen in a timely fashion from the cooling bath to the impact position, and puts the focus back on the machine performance. For NIST, it also reduces the time and cost for certifying new verification lots. For one of the low-energy lots tested with a C-shaped hammer, we experienced two specimens jamming, which yielded unusually high values of absorbed energy. For both specimens, the signs of jamming were clearly visible. For all the low-energy lots investigated, jamming is slightly more likely to occur at 21 °C than at -40 °C, since at room temperature low-energy samples tend to remain in the test area after impact rather than exiting in the opposite direction of the pendulum swing. In the evaluation of a verification set, any jammed specimen should be removed from the analyses.

  1. Autoverification process improvement by Six Sigma approach: Clinical chemistry & immunoassay.

    PubMed

    Randell, Edward W; Short, Garry; Lee, Natasha; Beresford, Allison; Spencer, Margaret; Kennell, Marina; Moores, Zoë; Parry, David

    2018-05-01

    This study examines effectiveness of a project to enhance an autoverification (AV) system through application of Six Sigma (DMAIC) process improvement strategies. Similar AV systems set up at three sites underwent examination and modification to produce improved systems while monitoring proportions of samples autoverified, the time required for manual review and verification, sample processing time, and examining characteristics of tests not autoverified. This information was used to identify areas for improvement and monitor the impact of changes. Use of reference range based criteria had the greatest impact on the proportion of tests autoverified. To improve AV process, reference range based criteria was replaced with extreme value limits based on a 99.5% test result interval, delta check criteria were broadened, and new specimen consistency rules were implemented. Decision guidance tools were also developed to assist staff using the AV system. The mean proportion of tests and samples autoverified improved from <62% for samples and <80% for tests, to >90% for samples and >95% for tests across all three sites. The new AV system significantly decreased turn-around time and total sample review time (to about a third), however, time spent for manual review of held samples almost tripled. There was no evidence of compromise to the quality of testing process and <1% of samples held for exceeding delta check or extreme limits required corrective action. The Six Sigma (DMAIC) process improvement methodology was successfully applied to AV systems resulting in an increase in overall test and sample AV by >90%, improved turn-around time, reduced time for manual verification, and with no obvious compromise to quality or error detection. Copyright © 2018 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  2. Independent Verification Final Summary Report for the David Witherspoon, Inc. 1630 Site Knoxville, Tennessee

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    P.C. Weaver

    2009-04-29

    The primary objective of the independent verification was to determine if BJC performed the appropriate actions to meet the specified “hot spot” cleanup criteria of 500 picocuries per gram (pCi/g) uranium-238 (U-238) in surface soil. Specific tasks performed by the independent verification team (IVT) to satisfy this objective included: 1) performing radiological walkover surveys, and 2) collecting soil samples for independent analyses. The independent verification (IV) efforts were designed to evaluate radioactive contaminants (specifically U-238) in the exposed surfaces below one foot of the original site grade, given that the top one foot layer of soil on the site wasmore » removed in its entirety.« less

  3. INNOVATIVE TECHNOLOGY VERIFICATION REPORT XRF ...

    EPA Pesticide Factsheets

    The Elvatech, Ltd. ElvaX (ElvaX) x-ray fluorescence (XRF) analyzer distributed in the United States by Xcalibur XRF Services (Xcalibur), was demonstrated under the U.S. Environmental Protection Agency (EPA) Superfund Innovative Technology Evaluation (SITE) Program. The field portion of the demonstration was conducted in January 2005 at the Kennedy Athletic, Recreational and Social Park (KARS) at Kennedy Space Center on Merritt Island, Florida. The demonstration was designed to collect reliable performance and cost data for the ElvaX analyzer and seven other commercially available XRF instruments for measuring trace elements in soil and sediment. The performance and cost data were evaluated to document the relative performance of each XRF instrument. This innovative technology verification report describes the objectives and the results of that evaluation and serves to verify the performance and cost of the ElvaX analyzer. Separate reports have been prepared for the other XRF instruments that were evaluated as part of the demonstration. The objectives of the evaluation included determining each XRF instrument’s accuracy, precision, sample throughput, and tendency for matrix effects. To fulfill these objectives, the field demonstration incorporated the analysis of 326 prepared samples of soil and sediment that contained 13 target elements. The prepared samples included blends of environmental samples from nine different sample collection sites as well as s

  4. GENERIC VERIFICATION PROTOCOL FOR THE VERIFICATION OF PESTICIDE SPRAY DRIFT REDUCTION TECHNOLOGIES FOR ROW AND FIELD CROPS

    EPA Science Inventory

    This ETV program generic verification protocol was prepared and reviewed for the Verification of Pesticide Drift Reduction Technologies project. The protocol provides a detailed methodology for conducting and reporting results from a verification test of pesticide drift reductio...

  5. Uranium Enrichment Safeguards

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Demuth, Scott F.; Trahan, Alexis Chanel

    2017-06-26

    DIV of facility layout, material flows, and other information provided in the DIQ. Material accountancy through an annual PIV and a number of interim inventory verifications, including UF6 cylinder identification and counting, NDA of cylinders, and DA on a sample collection of UF6. Application of C/S technologies utilizing seals and tamper-indicating devices (TIDs) on cylinders, containers, storage rooms, and IAEA instrumentation to provide continuity of knowledge between inspection. Verification of the absence of undeclared material and operations, especially HEU production, through SNRIs, LFUA of cascade halls, and environmental swipe sampling

  6. Remaining Sites Verification Package for the 1607-B2 Septic System and 100-B-14:2 Sanitary Sewer System, Waste Site Reclassification Form 2004-006

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    L. M. Dittmer

    The 100-B-14:2 subsite encompasses the former sanitary sewer feeder lines associated with the 1607-B2 and 1607-B7 septic systems. Feeder lines associated with the 185/190-B building have also been identified as the 100-B-14:8 subsite, and feeder lines associated with the 1607-B7 septic system have also been identified as the 100-B-14:9 subsite. These two subsites have been administratively cancelled to resolve the redundancy. The results of verification sampling show that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also demonstrate that residual contaminant concentrations are protective of groundwater and themore » Columbia River.« less

  7. 49 CFR Appendix D to Part 229 - Criteria for Certification of Crashworthy Event Recorder Memory Module

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... that the ERMM meets the performance criteria contained in this appendix and that test verification data are available to a railroad or to FRA upon request. 2. The test verification data shall contain, at a minimum, all pertinent original data logs and documentation that the test sample preparation, test set up...

  8. 49 CFR Appendix D to Part 229 - Criteria for Certification of Crashworthy Event Recorder Memory Module

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... that the ERMM meets the performance criteria contained in this appendix and that test verification data are available to a railroad or to FRA upon request. 2. The test verification data shall contain, at a minimum, all pertinent original data logs and documentation that the test sample preparation, test set up...

  9. 49 CFR Appendix D to Part 229 - Criteria for Certification of Crashworthy Event Recorder Memory Module

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... that the ERMM meets the performance criteria contained in this appendix and that test verification data are available to a railroad or to FRA upon request. 2. The test verification data shall contain, at a minimum, all pertinent original data logs and documentation that the test sample preparation, test set up...

  10. 49 CFR Appendix D to Part 229 - Criteria for Certification of Crashworthy Event Recorder Memory Module

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... that the ERMM meets the performance criteria contained in this appendix and that test verification data are available to a railroad or to FRA upon request. 2. The test verification data shall contain, at a minimum, all pertinent original data logs and documentation that the test sample preparation, test set up...

  11. 49 CFR Appendix D to Part 229 - Criteria for Certification of Crashworthy Event Recorder Memory Module

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... that the ERMM meets the performance criteria contained in this appendix and that test verification data are available to a railroad or to FRA upon request. 2. The test verification data shall contain, at a minimum, all pertinent original data logs and documentation that the test sample preparation, test set up...

  12. Code Verification Results of an LLNL ASC Code on Some Tri-Lab Verification Test Suite Problems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anderson, S R; Bihari, B L; Salari, K

    As scientific codes become more complex and involve larger numbers of developers and algorithms, chances for algorithmic implementation mistakes increase. In this environment, code verification becomes essential to building confidence in the code implementation. This paper will present first results of a new code verification effort within LLNL's B Division. In particular, we will show results of code verification of the LLNL ASC ARES code on the test problems: Su Olson non-equilibrium radiation diffusion, Sod shock tube, Sedov point blast modeled with shock hydrodynamics, and Noh implosion.

  13. Quantum supremacy in constant-time measurement-based computation: A unified architecture for sampling and verification

    NASA Astrophysics Data System (ADS)

    Miller, Jacob; Sanders, Stephen; Miyake, Akimasa

    2017-12-01

    While quantum speed-up in solving certain decision problems by a fault-tolerant universal quantum computer has been promised, a timely research interest includes how far one can reduce the resource requirement to demonstrate a provable advantage in quantum devices without demanding quantum error correction, which is crucial for prolonging the coherence time of qubits. We propose a model device made of locally interacting multiple qubits, designed such that simultaneous single-qubit measurements on it can output probability distributions whose average-case sampling is classically intractable, under similar assumptions as the sampling of noninteracting bosons and instantaneous quantum circuits. Notably, in contrast to these previous unitary-based realizations, our measurement-based implementation has two distinctive features. (i) Our implementation involves no adaptation of measurement bases, leading output probability distributions to be generated in constant time, independent of the system size. Thus, it could be implemented in principle without quantum error correction. (ii) Verifying the classical intractability of our sampling is done by changing the Pauli measurement bases only at certain output qubits. Our usage of random commuting quantum circuits in place of computationally universal circuits allows a unique unification of sampling and verification, so they require the same physical resource requirements in contrast to the more demanding verification protocols seen elsewhere in the literature.

  14. New generation of universal modeling for centrifugal compressors calculation

    NASA Astrophysics Data System (ADS)

    Galerkin, Y.; Drozdov, A.

    2015-08-01

    The Universal Modeling method is in constant use from mid - 1990th. Below is presented the newest 6th version of the Method. The flow path configuration of 3D impellers is presented in details. It is possible to optimize meridian configuration including hub/shroud curvatures, axial length, leading edge position, etc. The new model of vaned diffuser includes flow non-uniformity coefficient based on CFD calculations. The loss model was built from the results of 37 experiments with compressors stages of different flow rates and loading factors. One common set of empirical coefficients in the loss model guarantees the efficiency definition within an accuracy of 0.86% at the design point and 1.22% along the performance curve. The model verification was made. Four multistage compressors performances with vane and vaneless diffusers were calculated. As the model verification was made, four multistage compressors performances with vane and vaneless diffusers were calculated. Two of these compressors have quite unusual flow paths. The modeling results were quite satisfactory in spite of these peculiarities. One sample of the verification calculations is presented in the text. This 6th version of the developed computer program is being already applied successfully in the design practice.

  15. [The Dose Effect of Isocenter Selection during IMRT Dose Verification with the 2D Chamber Array].

    PubMed

    Xie, Chuanbin; Cong, Xiaohu; Xu, Shouping; Dai, Xiangkun; Wang, Yunlai; Han, Lu; Gong, Hanshun; Ju, Zhongjian; Ge, Ruigang; Ma, Lin

    2015-03-01

    To investigate the dose effect of isocenter difference during IMRT dose verification with the 2D chamber array. The samples collected from 10 patients were respectively designed for IMRT plans, the isocenter of which was independently defined as P(o), P(x) and P(y). P(o) was fixed on the target center and the other points shifted 8cm from the target center in the orientation of x/y. The PTW729 was used for 2D dose verification in the 3 groups which beams of plans were set to 0 degrees. The γ-analysis passing rates for the whole plan and each beam were gotten using the different standards in the 3 groups, The results showed the mean passing rate of γ-analysis was highest in the P(o) group, and the mean passing rate of the whole plan was better than that of each beam. In addition, it became worse with the increase of dose leakage between the leaves in P(y) group. Therefore, the determination of isocenter has a visible effect for IMRT dose verification of the 2D chamber array, The isocenter of the planning design should be close to the geometric center of target.

  16. Data Report on Post-Irradiation Dimensional Change of AGC-1 Samples

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    William Windes

    This report summarizes the initial dimensional changes for loaded and unloaded AGC-1 samples. The dimensional change for all samples is presented as a function of dose. The data is further presented by graphite type and applied load levels to illustrate the differences between graphite forming processes and stress levels within the graphite components. While the three different loads placed on the samples have been verified [ ref: Larry Hull’s report] verification of the AGC-1 sample temperatures and dose levels are expected in the summer of 2012. Only estimated dose and temperature values for the samples are presented in this reportmore » to allow a partial analysis of the results.« less

  17. Transistor step stress program for JANTX2N4150

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Reliability analysis of the transistor JANTX2N4150 manufactured by General Semiconductor and Transitron is reported. The discrete devices were subjected to power and temperature step stress tests and then to electrical tests after completing the power/temperature step stress point. Control sample units were maintained for verification of the electrical parametric testing. Results are presented.

  18. Classification and Verification of Handwritten Signatures with Time Causal Information Theory Quantifiers.

    PubMed

    Rosso, Osvaldo A; Ospina, Raydonal; Frery, Alejandro C

    2016-01-01

    We present a new approach for handwritten signature classification and verification based on descriptors stemming from time causal information theory. The proposal uses the Shannon entropy, the statistical complexity, and the Fisher information evaluated over the Bandt and Pompe symbolization of the horizontal and vertical coordinates of signatures. These six features are easy and fast to compute, and they are the input to an One-Class Support Vector Machine classifier. The results are better than state-of-the-art online techniques that employ higher-dimensional feature spaces which often require specialized software and hardware. We assess the consistency of our proposal with respect to the size of the training sample, and we also use it to classify the signatures into meaningful groups.

  19. The Mars Science Laboratory Organic Check Material

    NASA Technical Reports Server (NTRS)

    Conrad, Pamela G.; Eigenbrode, J. E.; Mogensen, C. T.; VonderHeydt, M. O.; Glavin, D. P.; Mahaffy, P. M.; Johnson, J. A.

    2011-01-01

    The Organic Check Material (OCM) has been developed for use on the Mars Science Laboratory mission to serve as a sample standard for verification of organic cleanliness and characterization of potential sample alteration as a function of the sample acquisition and portioning process on the Curiosity rover. OCM samples will be acquired using the same procedures for drilling, portioning and delivery as are used to study martian samples with The Sample Analysis at Mars (SAM) instrument suite during MSL surface operations. Because the SAM suite is highly sensitive to organic molecules, the mission can better verify the cleanliness of Curiosity's sample acquisition hardware if a known material can be processed through SAM and compared with the results obtained from martian samples.

  20. 40 CFR 1065.309 - Continuous gas analyzer system-response and updating-recording verification-for gas analyzers...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... discrete-mode testing. For this check we consider water vapor a gaseous constituent. This verification does... for water removed from the sample done in post-processing according to § 1065.659 and it does not... humidification vessel that contains water. You must humidify NO2 span gas with another moist gas stream. We...

  1. 40 CFR 1065.309 - Continuous gas analyzer system-response and updating-recording verification-for gas analyzers...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... discrete-mode testing. For this check we consider water vapor a gaseous constituent. This verification does... for water removed from the sample done in post-processing according to § 1065.659 (40 CFR 1066.620 for... contains water. You must humidify NO2 span gas with another moist gas stream. We recommend humidifying your...

  2. Cleanup Verification Package for the 118-F-5 PNL Sawdust Pit

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    L. D. Habel

    2008-05-20

    This cleanup verification package documents completion of remedial action, sampling activities, and compliance with cleanup criteria for the 118-F-5 Burial Ground, the PNL (Pacific Northwest Laboratory) Sawdust Pit. The 118-F-5 Burial Ground was an unlined trench that received radioactive sawdust from the floors of animal pens in the 100-F Experimental Animal Farm.

  3. Comprehensive Evaluation and Implementation of Improvement Actions in Butcher Shops

    PubMed Central

    Leotta, Gerardo A.; Brusa, Victoria; Galli, Lucía; Adriani, Cristian; Linares, Luciano; Etcheverría, Analía; Sanz, Marcelo; Sucari, Adriana; Peral García, Pilar; Signorini, Marcelo

    2016-01-01

    Foodborne pathogens can cause acute and chronic diseases and produce a wide range of symptoms. Since the consumption of ground beef is a risk factor for infections with some bacterial pathogens, we performed a comprehensive evaluation of butcher shops, implemented improvement actions for both butcher shops and consumers, and verified the impact of those actions implemented. A comprehensive evaluation was made and risk was quantified on a 1–100 scale as high-risk (1–40), moderate-risk (41–70) or low-risk (71–100). A total of 172 raw ground beef and 672 environmental samples were collected from 86 butcher shops during the evaluation (2010–2011) and verification (2013) stages of the study. Ground beef samples were analyzed for mesophilic aerobic organisms, Escherichia coli and coagulase-positive Staphylococcus aureus enumeration. Salmonella spp., E. coli O157:H7, non-O157 Shiga toxin-producing E. coli (STEC), and Listeria monocytogenes were detected and isolated from all samples. Risk quantification resulted in 43 (50.0%) high-risk, 34 (39.5%) moderate-risk, and nine (10.5%) low-risk butcher shops. Training sessions for 498 handlers and 4,506 consumers were held. Re-evaluation by risk quantification and microbiological analyses resulted in 19 (22.1%) high-risk, 42 (48.8%) moderate-risk and 25 (29.1%) low-risk butcher shops. The count of indicator microorganisms decreased with respect to the 2010–2011 period. After the implementation of improvement actions, the presence of L. monocytogenes, E. coli O157:H7 and stx genes in ground beef decreased. Salmonella spp. was isolated from 10 (11.6%) ground beef samples, without detecting statistically significant differences between both study periods (evaluation and verification). The percentage of pathogens in environmental samples was reduced in the verification period (Salmonella spp., 1.5%; L. monocytogenes, 10.7%; E. coli O157:H7, 0.6%; non-O157 STEC, 6.8%). Risk quantification was useful to identify those relevant facts in butcher shops. The reduction of contamination in ground beef and the environment was possible after training handlers based on the problems identified in their own butcher shops. Our results confirm the feasibility of implementing a comprehensive risk management program in butcher shops, and the importance of information campaigns targeting consumers. Further collaborative efforts would be necessary to improve foodstuffs safety at retail level and at home. PMID:27618439

  4. Comprehensive Evaluation and Implementation of Improvement Actions in Butcher Shops.

    PubMed

    Leotta, Gerardo A; Brusa, Victoria; Galli, Lucía; Adriani, Cristian; Linares, Luciano; Etcheverría, Analía; Sanz, Marcelo; Sucari, Adriana; Peral García, Pilar; Signorini, Marcelo

    2016-01-01

    Foodborne pathogens can cause acute and chronic diseases and produce a wide range of symptoms. Since the consumption of ground beef is a risk factor for infections with some bacterial pathogens, we performed a comprehensive evaluation of butcher shops, implemented improvement actions for both butcher shops and consumers, and verified the impact of those actions implemented. A comprehensive evaluation was made and risk was quantified on a 1-100 scale as high-risk (1-40), moderate-risk (41-70) or low-risk (71-100). A total of 172 raw ground beef and 672 environmental samples were collected from 86 butcher shops during the evaluation (2010-2011) and verification (2013) stages of the study. Ground beef samples were analyzed for mesophilic aerobic organisms, Escherichia coli and coagulase-positive Staphylococcus aureus enumeration. Salmonella spp., E. coli O157:H7, non-O157 Shiga toxin-producing E. coli (STEC), and Listeria monocytogenes were detected and isolated from all samples. Risk quantification resulted in 43 (50.0%) high-risk, 34 (39.5%) moderate-risk, and nine (10.5%) low-risk butcher shops. Training sessions for 498 handlers and 4,506 consumers were held. Re-evaluation by risk quantification and microbiological analyses resulted in 19 (22.1%) high-risk, 42 (48.8%) moderate-risk and 25 (29.1%) low-risk butcher shops. The count of indicator microorganisms decreased with respect to the 2010-2011 period. After the implementation of improvement actions, the presence of L. monocytogenes, E. coli O157:H7 and stx genes in ground beef decreased. Salmonella spp. was isolated from 10 (11.6%) ground beef samples, without detecting statistically significant differences between both study periods (evaluation and verification). The percentage of pathogens in environmental samples was reduced in the verification period (Salmonella spp., 1.5%; L. monocytogenes, 10.7%; E. coli O157:H7, 0.6%; non-O157 STEC, 6.8%). Risk quantification was useful to identify those relevant facts in butcher shops. The reduction of contamination in ground beef and the environment was possible after training handlers based on the problems identified in their own butcher shops. Our results confirm the feasibility of implementing a comprehensive risk management program in butcher shops, and the importance of information campaigns targeting consumers. Further collaborative efforts would be necessary to improve foodstuffs safety at retail level and at home.

  5. Control and Non-Payload Communications (CNPC) Prototype Radio Verification Test Report

    NASA Technical Reports Server (NTRS)

    Bishop, William D.; Frantz, Brian D.; Thadhani, Suresh K.; Young, Daniel P.

    2017-01-01

    This report provides an overview and results from the verification of the specifications that defines the operational capabilities of the airborne and ground, L Band and C Band, Command and Non-Payload Communications radio link system. An overview of system verification is provided along with an overview of the operation of the radio. Measurement results are presented for verification of the radios operation.

  6. Perspectives of human verification via binary QRS template matching of single-lead and 12-lead electrocardiogram.

    PubMed

    Krasteva, Vessela; Jekova, Irena; Schmid, Ramun

    2018-01-01

    This study aims to validate the 12-lead electrocardiogram (ECG) as a biometric modality based on two straightforward binary QRS template matching characteristics. Different perspectives of the human verification problem are considered, regarding the optimal lead selection and stability over sample size, gender, age, heart rate (HR). A clinical 12-lead resting ECG database, including a population of 460 subjects with two-session recordings (>1 year apart) is used. Cost-effective strategies for extraction of personalized QRS patterns (100ms) and binary template matching estimate similarity in the time scale (matching time) and dissimilarity in the amplitude scale (mismatch area). The two-class person verification task, taking the decision to validate or to reject the subject identity is managed by linear discriminant analysis (LDA). Non-redundant LDA models for different lead configurations (I,II,III,aVF,aVL,aVF,V1-V6) are trained on the first half of 230 subjects by stepwise feature selection until maximization of the area under the receiver operating characteristic curve (ROC AUC). The operating point on the training ROC at equal error rate (EER) is tested on the independent dataset (second half of 230 subjects) to report unbiased validation of test-ROC AUC and true verification rate (TVR = 100-EER). The test results are further evaluated in groups by sample size, gender, age, HR. The optimal QRS pattern projection for single-lead ECG biometric modality is found in the frontal plane sector (60°-0°) with best (Test-AUC/TVR) for lead II (0.941/86.8%) and slight accuracy drop for -aVR (-0.017/-1.4%), I (-0.01/-1.5%). Chest ECG leads have degrading accuracy from V1 (0.885/80.6%) to V6 (0.799/71.8%). The multi-lead ECG improves verification: 6-chest (0.97/90.9%), 6-limb (0.986/94.3%), 12-leads (0.995/97.5%). The QRS pattern matching model shows stable performance for verification of 10 to 230 individuals; insignificant degradation of TVR in women by (1.2-3.6%), adults ≥70 years (3.7%), younger <40 years (1.9%), HR<60bpm (1.2%), HR>90bpm (3.9%), no degradation for HR change (0 to >20bpm).

  7. Internet Pornography Use and Sexual Body Image in a Dutch Sample

    PubMed Central

    Cranney, Stephen

    2016-01-01

    Objectives A commonly attributed cause of sexual body image dissatisfaction is pornography use. This relationship has received little verification. Methods The relationship between sexual body image dissatisfaction and Internet pornography use was tested using a large-N sample of Dutch respondents. Results/Conclusion Penis size dissatisfaction is associated with pornography use. The relationship between pornography use and breast size dissatisfaction is null. These results support prior speculation and self-reports about the relationship between pornography use and sexual body image among men. These results also support a prior null finding of the relationship between breast size satisfaction for women and pornography use. PMID:26918066

  8. High-speed autoverifying technology for printed wiring boards

    NASA Astrophysics Data System (ADS)

    Ando, Moritoshi; Oka, Hiroshi; Okada, Hideo; Sakashita, Yorihiro; Shibutani, Nobumi

    1996-10-01

    We have developed an automated pattern verification technique. The output of an automated optical inspection system contains many false alarms. Verification is needed to distinguish between minor irregularities and serious defects. In the past, this verification was usually done manually, which led to unsatisfactory product quality. The goal of our new automated verification system is to detect pattern features on surface mount technology boards. In our system, we employ a new illumination method, which uses multiple colors and multiple direction illumination. Images are captured with a CCD camera. We have developed a new algorithm that uses CAD data for both pattern matching and pattern structure determination. This helps to search for patterns around a defect and to examine defect definition rules. These are processed with a high speed workstation and a hard-wired circuits. The system can verify a defect within 1.5 seconds. The verification system was tested in a factory. It verified 1,500 defective samples and detected all significant defects with only a 0.1 percent of error rate (false alarm).

  9. Progress on an external occulter testbed at flight Fresnel numbers

    NASA Astrophysics Data System (ADS)

    Kim, Yunjong; Sirbu, Dan; Galvin, Michael; Kasdin, N. Jeremy; Vanderbei, Robert J.

    2016-01-01

    An external occulter is a spacecraft flown along the line-of-sight of a space telescope to suppress starlight and enable high-contrast direct imaging of exoplanets. Laboratory verification of occulter designs is necessary to validate the optical models used to design and predict occulter performance. At Princeton, we have designed and built a testbed that allows verification of scaled occulter designs whose suppressed shadow is mathematically identical to that of space occulters. The occulter testbed uses 78 m optical propagation distance to realize the flight Fresnel numbers. We will use an etched silicon mask as the occulter. The occulter is illuminated by a diverging laser beam to reduce the aberrations from the optics before the occulter. Here, we present first light result of a sample design operating at a flight Fresnel number and the mechanical design of the testbed. We compare the experimental results with simulations that predict the ultimate contrast performance.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    V Yashchuk; R Conley; E Anderson

    Verification of the reliability of metrology data from high quality X-ray optics requires that adequate methods for test and calibration of the instruments be developed. For such verification for optical surface profilometers in the spatial frequency domain, a modulation transfer function (MTF) calibration method based on binary pseudo-random (BPR) gratings and arrays has been suggested [1] and [2] and proven to be an effective calibration method for a number of interferometric microscopes, a phase shifting Fizeau interferometer, and a scatterometer [5]. Here we describe the details of development of binary pseudo-random multilayer (BPRML) test samples suitable for characterization of scanningmore » (SEM) and transmission (TEM) electron microscopes. We discuss the results of TEM measurements with the BPRML test samples fabricated from a WiSi2/Si multilayer coating with pseudo-randomly distributed layers. In particular, we demonstrate that significant information about the metrological reliability of the TEM measurements can be extracted even when the fundamental frequency of the BPRML sample is smaller than the Nyquist frequency of the measurements. The measurements demonstrate a number of problems related to the interpretation of the SEM and TEM data. Note that similar BPRML test samples can be used to characterize X-ray microscopes. Corresponding work with X-ray microscopes is in progress.« less

  11. 40 CFR 1066.135 - Linearity verification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CVS, double-dilution, and partial-flow systems. (3) PM sample. (4) Chiller sample, for gaseous sampling systems that use thermal chillers to dry samples, and that use chiller temperature to calculate dewpoint at the chiller outlet. For testing, if you choose to use the high alarm temperature setpoint for...

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yashchuk, V.V.; Conley, R.; Anderson, E.H.

    Verification of the reliability of metrology data from high quality X-ray optics requires that adequate methods for test and calibration of the instruments be developed. For such verification for optical surface profilometers in the spatial frequency domain, a modulation transfer function (MTF) calibration method based on binarypseudo-random (BPR) gratings and arrays has been suggested and and proven to be an effective calibration method for a number of interferometric microscopes, a phase shifting Fizeau interferometer, and a scatterometer. Here we describe the details of development of binarypseudo-random multilayer (BPRML) test samples suitable for characterization of scanning (SEM) and transmission (TEM) electronmore » microscopes. We discuss the results of TEM measurements with the BPRML test samples fabricated from a WiSi{sub 2}/Si multilayer coating with pseudo-randomly distributed layers. In particular, we demonstrate that significant information about the metrological reliability of the TEM measurements can be extracted even when the fundamental frequency of the BPRML sample is smaller than the Nyquist frequency of the measurements. The measurements demonstrate a number of problems related to the interpretation of the SEM and TEM data. Note that similar BPRML testsamples can be used to characterize X-ray microscopes. Corresponding work with X-ray microscopes is in progress.« less

  13. Soil Amendments to Reduce Bioavailability of Metals in Soils: Experimental Studies and Spectroscopic Verification

    DTIC Science & Technology

    2008-07-01

    Leachate . ................................ 56 xi Table 24. Smelter Site Soil Lettuce Germination Percentage...sand soil (Table 22). This discovery was contrary to the hypothesized results. Archived samples of leachate from each treatment were examined...but after further investigation ,the pH and EC of the New Jersey leachate showed no remarkable differences between the unamended or sand unamended

  14. 77 FR 67777 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-14

    ... subsequent soil samples showed levels of metals at or below generic residential criteria or background values... 1994- 1996 and additional sampling between 1998 and 2007. Area A--Site Entrance: Soil boring samples... verification samples. Additional soil samples were collected from the same location as the previous collection...

  15. Classification and Verification of Handwritten Signatures with Time Causal Information Theory Quantifiers

    PubMed Central

    Ospina, Raydonal; Frery, Alejandro C.

    2016-01-01

    We present a new approach for handwritten signature classification and verification based on descriptors stemming from time causal information theory. The proposal uses the Shannon entropy, the statistical complexity, and the Fisher information evaluated over the Bandt and Pompe symbolization of the horizontal and vertical coordinates of signatures. These six features are easy and fast to compute, and they are the input to an One-Class Support Vector Machine classifier. The results are better than state-of-the-art online techniques that employ higher-dimensional feature spaces which often require specialized software and hardware. We assess the consistency of our proposal with respect to the size of the training sample, and we also use it to classify the signatures into meaningful groups. PMID:27907014

  16. Circular Samples as Objects for Magnetic Resonance Imaging - Mathematical Simulation, Experimental Results

    NASA Astrophysics Data System (ADS)

    Frollo, Ivan; Krafčík, Andrej; Andris, Peter; Přibil, Jiří; Dermek, Tomáš

    2015-12-01

    Circular samples are the frequent objects of "in-vitro" investigation using imaging method based on magnetic resonance principles. The goal of our investigation is imaging of thin planar layers without using the slide selection procedure, thus only 2D imaging or imaging of selected layers of samples in circular vessels, eppendorf tubes,.. compulsorily using procedure "slide selection". In spite of that the standard imaging methods was used, some specificity arise when mathematical modeling of these procedure is introduced. In the paper several mathematical models were presented that were compared with real experimental results. Circular magnetic samples were placed into the homogenous magnetic field of a low field imager based on nuclear magnetic resonance. For experimental verification an MRI 0.178 Tesla ESAOTE Opera imager was used.

  17. Computer Simulations to Study Diffraction Effects of Stacking Faults in Beta-SiC: II. Experimental Verification. 2; Experimental Verification

    NASA Technical Reports Server (NTRS)

    Pujar, Vijay V.; Cawley, James D.; Levine, S. (Technical Monitor)

    2000-01-01

    Earlier results from computer simulation studies suggest a correlation between the spatial distribution of stacking errors in the Beta-SiC structure and features observed in X-ray diffraction patterns of the material. Reported here are experimental results obtained from two types of nominally Beta-SiC specimens, which yield distinct XRD data. These samples were analyzed using high resolution transmission electron microscopy (HRTEM) and the stacking error distribution was directly determined. The HRTEM results compare well to those deduced by matching the XRD data with simulated spectra, confirming the hypothesis that the XRD data is indicative not only of the presence and density of stacking errors, but also that it can yield information regarding their distribution. In addition, the stacking error population in both specimens is related to their synthesis conditions and it appears that it is similar to the relation developed by others to explain the formation of the corresponding polytypes.

  18. Assessment of test methods for evaluating effectiveness of cleaning flexible endoscopes.

    PubMed

    Washburn, Rebecca E; Pietsch, Jennifer J

    2018-06-01

    Strict adherence to each step of reprocessing is imperative to removing potentially infectious agents. Multiple methods for verifying proper reprocessing exist; however, each presents challenges and limitations, and best practice within the industry has not been established. Our goal was to evaluate endoscope cleaning verification tests with particular interest in the evaluation of the manual cleaning step. The results of the cleaning verification tests were compared with microbial culturing to see if a positive cleaning verification test would be predictive of microbial growth. This study was conducted at 2 high-volume endoscopy units within a multisite health care system. Each of the 90 endoscopes were tested for adenosine triphosphate, protein, microbial growth via agar plate, and rapid gram-negative culture via assay. The endoscopes were tested in 3 locations: the instrument channel, control knob, and elevator mechanism. This analysis showed substantial level of agreement between protein detection postmanual cleaning and protein detection post-high-level disinfection at the control head for scopes sampled sequentially. This study suggests that if protein is detected postmanual cleaning, there is a significant likelihood that protein will also be detected post-high-level disinfection. It also infers that a cleaning verification test is not predictive of microbial growth. Copyright © 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  19. LLNL Genomic Assessment: Viral and Bacterial Sequencing Needs for TMTI, Task 1.4.2 Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Slezak, T; Borucki, M; Lam, M

    Good progress has been made on both bacterial and viral sequencing by the TMTI centers. While access to appropriate samples is a limiting factor to throughput, excellent progress has been made with respect to getting agreements in place with key sources of relevant materials. Sharing of sequenced genomes funded by TMTI has been extremely limited to date. The April 2010 exercise should force a resolution to this, but additional managerial pressures may be needed to ensure that rapid sharing of TMTI-funded sequencing occurs, regardless of collaborator constraints concerning ultimate publication(s). Policies to permit TMTI-internal rapid sharing of sequenced genomes shouldmore » be written into all TMTI agreements with collaborators now being negotiated. TMTI needs to establish a Web-based system for tracking samples destined for sequencing. This includes metadata on sample origins and contributor, information on sample shipment/receipt, prioritization by TMTI, assignment to one or more sequencing centers (including possible TMTI-sponsored sequencing at a contributor site), and status history of the sample sequencing effort. While this system could be a component of the AFRL system, it is not part of any current development effort. Policy and standardized procedures are needed to ensure appropriate verification of all TMTI samples prior to the investment in sequencing. PCR, arrays, and classical biochemical tests are examples of potential verification methods. Verification is needed to detect miss-labeled, degraded, mixed or contaminated samples. Regular QC exercises are needed to ensure that the TMTI-funded centers are meeting all standards for producing quality genomic sequence data.« less

  20. OH/H2O Detection Capability Evaluation on Chang'e-5 Lunar Mineralogical Spectrometer (LMS)

    NASA Astrophysics Data System (ADS)

    Liu, Bin; Ren, Xin; Liu, Jianjun; Li, Chunlai; Mu, Lingli; Deng, Liyan

    2016-10-01

    The Chang'e-5 (CE-5) lunar sample return mission is scheduled to launch in 2017 to bring back lunar regolith and drill samples. The Chang'e-5 Lunar Mineralogical Spectrometer (LMS), as one of the three sets of scientific payload installed on the lander, is used to collect in-situ spectrum and analyze the mineralogical composition of the samplingsite. It can also help to select the sampling site, and to compare the measured laboratory spectrum of returned sample with in-situ data. LMS employs acousto-optic tunable filters (AOTFs) and is composed of a VIS/NIR module (0.48μm-1.45μm) and an IR module (1.4μm -3.2μm). It has spectral resolution ranging from 3 to 25 nm, with a field of view (FOV) of 4.24°×4.24°. Unlike Chang'e-3 VIS/NIR Imaging Spectrometer (VNIS), the spectral coverage of LMS is extended from 2.4μm to 3.2μm, which has capability to identify H2O/OH absorption features around 2.7μm. An aluminum plate and an Infragold plate are fixed in the dust cover, being used as calibration targets in the VIS/NIR and IR spectral range respectively when the dust cover is open. Before launch, a ground verification test of LMS needs to be conducted in order to: 1) test and verify the detection capability of LMS through evaluation on the quality of image and spectral data collected for the simulated lunar samples; and 2) evaluate the accuracy of data processing methods by the simulation of instrument working on the moon. The ground verification test will be conducted both in the lab and field. The spectra of simulated lunar regolith/mineral samples will be collected simultaneously by the LMS and two calibrated spectrometers: a FTIR spectrometer (Model 102F) and an ASD FieldSpec 4 Hi-Res spectrometer. In this study, the results of the LMS ground verification test will be reported, and OH/H2O Detection Capability will be evaluated especially.

  1. 40 CFR 1065.342 - Sample dryer verification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... condensation as required in § 1065.145(d)(1)(i). We recommend that the sample system components be maintained at least 5 °C above the local humidified gas dewpoint to prevent aqueous condensation. (5) Measure...

  2. 40 CFR 1065.342 - Sample dryer verification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... condensation as required in § 1065.145(d)(1)(i). We recommend that the sample system components be maintained at least 5 °C above the local humidified gas dewpoint to prevent aqueous condensation. (5) Measure...

  3. 40 CFR 1065.342 - Sample dryer verification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... condensation as required in § 1065.145(d)(1)(i). We recommend that the sample system components be maintained at least 5 °C above the local humidified gas dewpoint to prevent aqueous condensation. (5) Measure...

  4. 40 CFR 761.130 - Sampling requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... developed by the Midwest Research Institute (MRI) for use in enforcement inspections: “Verification of PCB... the MRI report “Field Manual for Grid Sampling of PCB Spill Sites to Verify Cleanup.” Both the MRI...

  5. 40 CFR 761.130 - Sampling requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... developed by the Midwest Research Institute (MRI) for use in enforcement inspections: “Verification of PCB... the MRI report “Field Manual for Grid Sampling of PCB Spill Sites to Verify Cleanup.” Both the MRI...

  6. 40 CFR 761.130 - Sampling requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... developed by the Midwest Research Institute (MRI) for use in enforcement inspections: “Verification of PCB... the MRI report “Field Manual for Grid Sampling of PCB Spill Sites to Verify Cleanup.” Both the MRI...

  7. Design and Realization of Controllable Ultrasonic Fault Detector Automatic Verification System

    NASA Astrophysics Data System (ADS)

    Sun, Jing-Feng; Liu, Hui-Ying; Guo, Hui-Juan; Shu, Rong; Wei, Kai-Li

    The ultrasonic flaw detection equipment with remote control interface is researched and the automatic verification system is developed. According to use extensible markup language, the building of agreement instruction set and data analysis method database in the system software realizes the controllable designing and solves the diversification of unreleased device interfaces and agreements. By using the signal generator and a fixed attenuator cascading together, a dynamic error compensation method is proposed, completes what the fixed attenuator does in traditional verification and improves the accuracy of verification results. The automatic verification system operating results confirms that the feasibility of the system hardware and software architecture design and the correctness of the analysis method, while changes the status of traditional verification process cumbersome operations, and reduces labor intensity test personnel.

  8. Applying Independent Verification and Validation to Automatic Test Equipment

    NASA Technical Reports Server (NTRS)

    Calhoun, Cynthia C.

    1997-01-01

    This paper describes a general overview of applying Independent Verification and Validation (IV&V) to Automatic Test Equipment (ATE). The overview is not inclusive of all IV&V activities that can occur or of all development and maintenance items that can be validated and verified, during the IV&V process. A sampling of possible IV&V activities that can occur within each phase of the ATE life cycle are described.

  9. A feasibility study of treatment verification using EPID cine images for hypofractionated lung radiotherapy

    NASA Astrophysics Data System (ADS)

    Tang, Xiaoli; Lin, Tong; Jiang, Steve

    2009-09-01

    We propose a novel approach for potential online treatment verification using cine EPID (electronic portal imaging device) images for hypofractionated lung radiotherapy based on a machine learning algorithm. Hypofractionated radiotherapy requires high precision. It is essential to effectively monitor the target to ensure that the tumor is within the beam aperture. We modeled the treatment verification problem as a two-class classification problem and applied an artificial neural network (ANN) to classify the cine EPID images acquired during the treatment into corresponding classes—with the tumor inside or outside of the beam aperture. Training samples were generated for the ANN using digitally reconstructed radiographs (DRRs) with artificially added shifts in the tumor location—to simulate cine EPID images with different tumor locations. Principal component analysis (PCA) was used to reduce the dimensionality of the training samples and cine EPID images acquired during the treatment. The proposed treatment verification algorithm was tested on five hypofractionated lung patients in a retrospective fashion. On average, our proposed algorithm achieved a 98.0% classification accuracy, a 97.6% recall rate and a 99.7% precision rate. This work was first presented at the Seventh International Conference on Machine Learning and Applications, San Diego, CA, USA, 11-13 December 2008.

  10. Functions of social support and self-verification in association with loneliness, depression, and stress.

    PubMed

    Wright, Kevin B; King, Shawn; Rosenberg, Jenny

    2014-01-01

    This study investigated the influence of social support and self-verification on loneliness, depression, and stress among 477 college students. The authors propose and test a theoretical model using structural equation modeling. The results indicated empirical support for the model, with self-verification mediating the relation between social support and health outcomes. The results have implications for social support and self-verification research, which are discussed along with directions for future research and limitations of the study.

  11. Remaining Sites Verification Package for the 100-F-46, 119-F Stack Sampling French Drain, Waste Site Reclassification Form 2008-021

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    J. M. Capron

    2008-08-08

    The 100-F-46 french drain consisted of a 1.5 to 3 m long, vertically buried, gravel-filled pipe that was approximately 1 m in diameter. Also included in this waste site was a 5 cm cast-iron pipeline that drained condensate from the 119-F Stack Sampling Building into the 100-F-46 french drain. In accordance with this evaluation, the confirmatory sampling results support a reclassification of this site to No Action. The current site conditions achieve the remedial action objectives and the corresponding remedial action goals established in the Remaining Sites ROD. The results of confirmatory sampling show that residual contaminant concentrations do notmore » preclude any future uses and allow for unrestricted use of shallow zone soils. The results also demonstrate that residual contaminant concentrations are protective of groundwater and the Columbia River.« less

  12. Enhancing pre-service physics teachers' creative thinking skills through HOT lab design

    NASA Astrophysics Data System (ADS)

    Malik, Adam; Setiawan, Agus; Suhandi, Andi; Permanasari, Anna

    2017-08-01

    A research on the implementation of HOT (Higher Order Thinking) Laboratory has been carried out. This research is aimed to compare increasing of creative thinking skills of pre-service physics teachers who receive physics lesson with HOT Lab and with verification lab for the topic of electric circuit. This research used a quasi-experiment methods with control group pretest-posttest design. The subject of the research is 40 Physics Education pre-service physics teachers of UIN Sunan Gunung Djati Bandung. Research samples were selected by class random sampling technique. Data on pre-service physics teachers' creative thinking skills were collected using test of creative thinking skills in the form of essay. The results of the research reveal that average of N-gain of creative thinking skills are <0,69> for pre-service physics teachers who received lesson with HOT Lab design and <0,39> for pre-service physics teachers who received lesson with verification lab, respectively. Therefore, we conclude that application of HOT Lab design is more effective to increase creative thinking skills in the lesson of electric circuit.

  13. Enhancing Communication Skills of Pre-service Physics Teacher through HOT Lab Related to Electric Circuit

    NASA Astrophysics Data System (ADS)

    Malik, A.; Setiawan, A.; Suhandi, A.; Permanasari, A.; Dirgantara, Y.; Yuniarti, H.; Sapriadil, S.; Hermita, N.

    2018-01-01

    This study aimed to investigate the improvement to pre-service teacher’s communication skills through Higher Order Thinking Laboratory (HOT Lab) on electric circuit topic. This research used the quasi-experiment method with pretest-posttest control group design. Research subjects were 60 students of Physics Education in UIN Sunan Gunung Djati Bandung. The sample was chosen by random sampling technique. Students’ communication skill data collected using a communication skills test instruments-essays form and observations sheets. The results showed that pre-service teacher communication skills using HOT Lab were higher than verification lab. Student’s communication skills in groups using HOT Lab were not influenced by gender. Communication skills could increase due to HOT Lab based on problems solving that can develop communication through hands-on activities. Therefore, the conclusion of this research shows the application of HOT Lab is more effective than the verification lab to improve communication skills of pre-service teachers in electric circuit topic and gender is not related to a person’s communication skills.

  14. Calibration of Ge gamma-ray spectrometers for complex sample geometries and matrices

    NASA Astrophysics Data System (ADS)

    Semkow, T. M.; Bradt, C. J.; Beach, S. E.; Haines, D. K.; Khan, A. J.; Bari, A.; Torres, M. A.; Marrantino, J. C.; Syed, U.-F.; Kitto, M. E.; Hoffman, T. J.; Curtis, P.

    2015-11-01

    A comprehensive study of the efficiency calibration and calibration verification of Ge gamma-ray spectrometers was performed using semi-empirical, computational Monte-Carlo (MC), and transfer methods. The aim of this study was to evaluate the accuracy of the quantification of gamma-emitting radionuclides in complex matrices normally encountered in environmental and food samples. A wide range of gamma energies from 59.5 to 1836.0 keV and geometries from a 10-mL jar to 1.4-L Marinelli beaker were studied on four Ge spectrometers with the relative efficiencies between 102% and 140%. Density and coincidence summing corrections were applied. Innovative techniques were developed for the preparation of artificial complex matrices from materials such as acidified water, polystyrene, ethanol, sugar, and sand, resulting in the densities ranging from 0.3655 to 2.164 g cm-3. They were spiked with gamma activity traceable to international standards and used for calibration verifications. A quantitative method of tuning MC calculations to experiment was developed based on a multidimensional chi-square paraboloid.

  15. Earth Science Enterprise Scientific Data Purchase Project: Verification and Validation

    NASA Technical Reports Server (NTRS)

    Jenner, Jeff; Policelli, Fritz; Fletcher, Rosea; Holecamp, Kara; Owen, Carolyn; Nicholson, Lamar; Dartez, Deanna

    2000-01-01

    This paper presents viewgraphs on the Earth Science Enterprise Scientific Data Purchase Project's verification,and validation process. The topics include: 1) What is Verification and Validation? 2) Why Verification and Validation? 3) Background; 4) ESE Data Purchas Validation Process; 5) Data Validation System and Ingest Queue; 6) Shipment Verification; 7) Tracking and Metrics; 8) Validation of Contract Specifications; 9) Earth Watch Data Validation; 10) Validation of Vertical Accuracy; and 11) Results of Vertical Accuracy Assessment.

  16. Precision, accuracy, cross reactivity and comparability of serum indices measurement on Abbott Architect c8000, Beckman Coulter AU5800 and Roche Cobas 6000 c501 clinical chemistry analyzers.

    PubMed

    Nikolac Gabaj, Nora; Miler, Marijana; Vrtarić, Alen; Hemar, Marina; Filipi, Petra; Kocijančić, Marija; Šupak Smolčić, Vesna; Ćelap, Ivana; Šimundić, Ana-Maria

    2018-04-25

    The aim of our study was to perform verification of serum indices on three clinical chemistry platforms. This study was done on three analyzers: Abbott Architect c8000, Beckman Coulter AU5800 (BC) and Roche Cobas 6000 c501. The following analytical specifications were verified: precision (two patient samples), accuracy (sample with the highest concentration of interferent was serially diluted and measured values compared to theoretical values), comparability (120 patients samples) and cross reactivity (samples with increasing concentrations of interferent were divided in two aliquots and remaining interferents were added in each aliquot. Measurements were done before and after adding interferents). Best results for precision were obtained for the H index (0.72%-2.08%). Accuracy for the H index was acceptable for Cobas and BC, while on Architect, deviations in the high concentration range were observed (y=0.02 [0.01-0.07]+1.07 [1.06-1.08]x). All three analyzers showed acceptable results in evaluating accuracy of L index and unacceptable results for I index. The H index was comparable between BC and both, Architect (Cohen's κ [95% CI]=0.795 [0.692-0.898]) and Roche (Cohen's κ [95% CI]=0.825 [0.729-0.922]), while Roche and Architect were not comparable. The I index was not comparable between all analyzer combinations, while the L index was only comparable between Abbott and BC. Cross reactivity analysis mostly showed that serum indices measurement is affected when a combination of interferences is present. There is heterogeneity between analyzers in the hemolysis, icteria, lipemia (HIL) quality performance. Verification of serum indices in routine work is necessary to establish analytical specifications.

  17. Image Guided Radiation Therapy (IGRT) Practice Patterns and IGRT's Impact on Workflow and Treatment Planning: Results From a National Survey of American Society for Radiation Oncology Members.

    PubMed

    Nabavizadeh, Nima; Elliott, David A; Chen, Yiyi; Kusano, Aaron S; Mitin, Timur; Thomas, Charles R; Holland, John M

    2016-03-15

    To survey image guided radiation therapy (IGRT) practice patterns, as well as IGRT's impact on clinical workflow and planning treatment volumes (PTVs). A sample of 5979 treatment site-specific surveys was e-mailed to the membership of the American Society for Radiation Oncology (ASTRO), with questions pertaining to IGRT modality/frequency, PTV expansions, method of image verification, and perceived utility/value of IGRT. On-line image verification was defined as images obtained and reviewed by the physician before treatment. Off-line image verification was defined as images obtained before treatment and then reviewed by the physician before the next treatment. Of 601 evaluable responses, 95% reported IGRT capabilities other than portal imaging. The majority (92%) used volumetric imaging (cone-beam CT [CBCT] or megavoltage CT), with volumetric imaging being the most commonly used modality for all sites except breast. The majority of respondents obtained daily CBCTs for head and neck intensity modulated radiation therapy (IMRT), lung 3-dimensional conformal radiation therapy or IMRT, anus or pelvis IMRT, prostate IMRT, and prostatic fossa IMRT. For all sites, on-line image verification was most frequently performed during the first few fractions only. No association was seen between IGRT frequency or CBCT utilization and clinical treatment volume to PTV expansions. Of the 208 academic radiation oncologists who reported working with residents, only 41% reported trainee involvement in IGRT verification processes. Consensus guidelines, further evidence-based approaches for PTV margin selection, and greater resident involvement are needed for standardized use of IGRT practices. Copyright © 2016 Elsevier Inc. All rights reserved.

  18. Analysis of Nerve Agent Metabolites from Hair for Long-Term Verification of Nerve Agent Exposure

    DTIC Science & Technology

    2016-05-09

    Analysis of Nerve Agent Metabolites from Hair for Long-Term Verification of Nerve Agent Exposure Amanda S. Appel,† John H. McDonough,‡ Joseph D...feasible. In this study, hair was evaluated as a long-term repository of nerve agent hydrolysis products. Pinacolyl methylphosphonic acid (PMPA...hydrolysis product of soman) and isopropyl methylphosphonic acid (IMPA; hydrolysis product of sarin) were extracted from hair samples with N,N

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yashchuk, Valeriy V; Conley, Raymond; Anderson, Erik H

    Verification of the reliability of metrology data from high quality x-ray optics requires that adequate methods for test and calibration of the instruments be developed. For such verification for optical surface profilometers in the spatial frequency domain, a modulation transfer function (MTF) calibration method based on binary pseudo-random (BPR) gratings and arrays has been suggested [Proc. SPIE 7077-7 (2007), Opt. Eng. 47(7), 073602-1-5 (2008)} and proven to be an effective calibration method for a number of interferometric microscopes, a phase shifting Fizeau interferometer, and a scatterometer [Nucl. Instr. and Meth. A 616, 172-82 (2010)]. Here we describe the details ofmore » development of binary pseudo-random multilayer (BPRML) test samples suitable for characterization of scanning (SEM) and transmission (TEM) electron microscopes. We discuss the results of TEM measurements with the BPRML test samples fabricated from a WiSi2/Si multilayer coating with pseudo randomly distributed layers. In particular, we demonstrate that significant information about the metrological reliability of the TEM measurements can be extracted even when the fundamental frequency of the BPRML sample is smaller than the Nyquist frequency of the measurements. The measurements demonstrate a number of problems related to the interpretation of the SEM and TEM data. Note that similar BPRML test samples can be used to characterize x-ray microscopes. Corresponding work with x-ray microscopes is in progress.« less

  20. Urine sampling and collection system

    NASA Technical Reports Server (NTRS)

    Fogal, G. L.; Mangialardi, J. K.; Reinhardt, C. G.

    1971-01-01

    This specification defines the performance and design requirements for the urine sampling and collection system engineering model and establishes requirements for its design, development, and test. The model shall provide conceptual verification of a system applicable to manned space flight which will automatically provide for collection, volume sensing, and sampling of urine.

  1. Certification and verification for Northrup Model NSC-01-0732 Fresnel lens concentrating solar collector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1979-03-01

    The certification and verification of the Northrup Model NSC-01-0732 Fresnel lens tracking solar collector are presented. A certification statement is included with signatures and a separate report on the structural analysis of the collector system. System verification against the Interim Performance Criteria are indicated by matrices with verification discussion, analysis, and enclosed test results.

  2. Simulation verification techniques study

    NASA Technical Reports Server (NTRS)

    Schoonmaker, P. B.; Wenglinski, T. H.

    1975-01-01

    Results are summarized of the simulation verification techniques study which consisted of two tasks: to develop techniques for simulator hardware checkout and to develop techniques for simulation performance verification (validation). The hardware verification task involved definition of simulation hardware (hardware units and integrated simulator configurations), survey of current hardware self-test techniques, and definition of hardware and software techniques for checkout of simulator subsystems. The performance verification task included definition of simulation performance parameters (and critical performance parameters), definition of methods for establishing standards of performance (sources of reference data or validation), and definition of methods for validating performance. Both major tasks included definition of verification software and assessment of verification data base impact. An annotated bibliography of all documents generated during this study is provided.

  3. Implications of sampling design and sample size for national carbon accounting systems

    Treesearch

    Michael Köhl; Andrew Lister; Charles T. Scott; Thomas Baldauf; Daniel Plugge

    2011-01-01

    Countries willing to adopt a REDD regime need to establish a national Measurement, Reporting and Verification (MRV) system that provides information on forest carbon stocks and carbon stock changes. Due to the extensive areas covered by forests the information is generally obtained by sample based surveys. Most operational sampling approaches utilize a combination of...

  4. Verification of three-microphone impedance tube method for measurement of transmission loss in aerogels

    NASA Astrophysics Data System (ADS)

    Connick, Robert J.

    Accurate measurement of normal incident transmission loss is essential for the acoustic characterization of building materials. In this research, a method of measuring normal incidence sound transmission loss proposed by Salissou et al. as a complement to standard E2611-09 of the American Society for Testing and Materials [Standard Test Method for Measurement of Normal Incidence Sound Transmission of Acoustical Materials Based on the Transfer Matrix Method (American Society for Testing and Materials, New York, 2009)] is verified. Two sam- ples from the original literature are used to verify the method as well as a Filtros RTM sample. Following the verification, several nano-material Aerogel samples are measured.

  5. Replacement Technologies for Precision Cleaning of Aerospace Hardware for Propellant Service

    NASA Technical Reports Server (NTRS)

    Beeson, Harold; Kirsch, Mike; Hornung, Steven; Biesinger, Paul

    1997-01-01

    The NASA White Sands Test Facility (WSTF) is developing cleaning and verification processes to replace currently used chlorofluorocarbon-l13- (CFC-113-) based processes. The processes being evaluated include both aqueous- and solvent-based techniques. Replacement technologies are being investigated for aerospace hardware and for gauges and instrumentation. This paper includes the findings of investigations of aqueous cleaning and verification of aerospace hardware using known contaminants, such as hydraulic fluid and commonly used oils. The results correlate nonvolatile residue with CFC 113. The studies also include enhancements to aqueous sampling for organic and particulate contamination. Although aqueous alternatives have been identified for several processes, a need still exists for nonaqueous solvent cleaning, such as the cleaning and cleanliness verification of gauges used for oxygen service. The cleaning effectiveness of tetrachloroethylene (PCE), trichloroethylene (TCE), ethanol, hydrochlorofluorocarbon 225 (HCFC 225), HCFC 141b, HFE 7100(R), and Vertrel MCA(R) was evaluated using aerospace gauges and precision instruments and then compared to the cleaning effectiveness of CFC 113. Solvents considered for use in oxygen systems were also tested for oxygen compatibility using high-pressure oxygen autogenous ignition and liquid oxygen mechanical impact testing.

  6. Quantitative real-time polymerase chain reaction for the verification of genomic imbalances detected by microarray-based comparative genomic hybridization.

    PubMed

    Yu, Shihui; Kielt, Matthew; Stegner, Andrew L; Kibiryeva, Nataliya; Bittel, Douglas C; Cooley, Linda D

    2009-12-01

    The American College of Medical Genetics guidelines for microarray analysis for constitutional cytogenetic abnormalities require abnormal or ambiguous results from microarray-based comparative genomic hybridization (aCGH) analysis be confirmed by an alternative method. We employed quantitative real-time polymerase chain reaction (qPCR) technology using SYBR Green I reagents for confirmation of 93 abnormal aCGH results (50 deletions and 43 duplications) and 54 parental samples. A novel qPCR protocol using DNA sequences coding for X-linked lethal diseases in males for designing reference primers was established. Of the 81 sets of test primers used for confirmation of 93 abnormal copy number variants (CNVs) in 80 patients, 71 sets worked after the initial primer design (88%), 9 sets were redesigned once, and 1 set twice because of poor amplification. Fifty-four parental samples were tested using 33 sets of test primers to follow up 34 CNVs in 30 patients. Nineteen CNVs were confirmed as inherited, 13 were negative in both parents, and 2 were inconclusive due to a negative result in a single parent. The qPCR assessment clarified aCGH results in two cases and corrected a fluorescence in situ hybridization result in one case. Our data illustrate that qPCR methodology using SYBR Green I reagents is accurate, highly sensitive, specific, rapid, and cost-effective for verification of chromosomal imbalances detected by aCGH in the clinical setting.

  7. Certification and verification for Northrup model NSC-01-0732 fresnel lens concentrating solar collector

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Structural analysis and certification of the collector system is presented. System verification against the interim performance criteria is presented and indicated by matrices. The verification discussion, analysis, and test results are also given.

  8. ETV TEST OF PCDD/F EMISSIONS MONITORING SYSTEMS

    EPA Science Inventory

    Four polychlorinated dibenzodioxin and furan (PCDD/F) emission monitors were tested under the EPA Environmental Technology and Verification (ETV) program. Two long-term sampling devices, the DioxinMonitoringSystem and Adsorption Method for Sampling Dioxins and Furans, and two sem...

  9. Environmental Technology Verification Coatings and Coating Equipment Program (ETV CCEP). High Transfer Efficiency Spray Equipment - Generic Verification Protocol (Revision 0)

    DTIC Science & Technology

    2006-09-30

    High-Pressure Waterjet • CO2 Pellet/Turbine Wheel • Ultrahigh-Pressure Waterjet 5 Process Water Reuse/Recycle • Cross-Flow Microfiltration ...documented on a process or laboratory form. Corrective action will involve taking all necessary steps to restore a measuring system to proper working order...In all cases, a nonconformance will be rectified before sample processing and analysis continues. If corrective action does not restore the

  10. Cross-correlation redshift calibration without spectroscopic calibration samples in DES Science Verification Data

    NASA Astrophysics Data System (ADS)

    Davis, C.; Rozo, E.; Roodman, A.; Alarcon, A.; Cawthon, R.; Gatti, M.; Lin, H.; Miquel, R.; Rykoff, E. S.; Troxel, M. A.; Vielzeuf, P.; Abbott, T. M. C.; Abdalla, F. B.; Allam, S.; Annis, J.; Bechtol, K.; Benoit-Lévy, A.; Bertin, E.; Brooks, D.; Buckley-Geer, E.; Burke, D. L.; Carnero Rosell, A.; Carrasco Kind, M.; Carretero, J.; Castander, F. J.; Crocce, M.; Cunha, C. E.; D'Andrea, C. B.; da Costa, L. N.; Desai, S.; Diehl, H. T.; Doel, P.; Drlica-Wagner, A.; Fausti Neto, A.; Flaugher, B.; Fosalba, P.; Frieman, J.; García-Bellido, J.; Gaztanaga, E.; Gerdes, D. W.; Giannantonio, T.; Gruen, D.; Gruendl, R. A.; Gutierrez, G.; Honscheid, K.; Jain, B.; James, D. J.; Jeltema, T.; Krause, E.; Kuehn, K.; Kuhlmann, S.; Kuropatkin, N.; Lahav, O.; Li, T. S.; Lima, M.; March, M.; Marshall, J. L.; Martini, P.; Melchior, P.; Ogando, R. L. C.; Plazas, A. A.; Romer, A. K.; Sanchez, E.; Scarpine, V.; Schindler, R.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, M.; Soares-Santos, M.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Vikram, V.; Walker, A. R.; Wechsler, R. H.

    2018-06-01

    Galaxy cross-correlations with high-fidelity redshift samples hold the potential to precisely calibrate systematic photometric redshift uncertainties arising from the unavailability of complete and representative training and validation samples of galaxies. However, application of this technique in the Dark Energy Survey (DES) is hampered by the relatively low number density, small area, and modest redshift overlap between photometric and spectroscopic samples. We propose instead using photometric catalogues with reliable photometric redshifts for photo-z calibration via cross-correlations. We verify the viability of our proposal using redMaPPer clusters from the Sloan Digital Sky Survey (SDSS) to successfully recover the redshift distribution of SDSS spectroscopic galaxies. We demonstrate how to combine photo-z with cross-correlation data to calibrate photometric redshift biases while marginalizing over possible clustering bias evolution in either the calibration or unknown photometric samples. We apply our method to DES Science Verification (DES SV) data in order to constrain the photometric redshift distribution of a galaxy sample selected for weak lensing studies, constraining the mean of the tomographic redshift distributions to a statistical uncertainty of Δz ˜ ±0.01. We forecast that our proposal can, in principle, control photometric redshift uncertainties in DES weak lensing experiments at a level near the intrinsic statistical noise of the experiment over the range of redshifts where redMaPPer clusters are available. Our results provide strong motivation to launch a programme to fully characterize the systematic errors from bias evolution and photo-z shapes in our calibration procedure.

  11. Cross-correlation redshift calibration without spectroscopic calibration samples in DES Science Verification Data

    DOE PAGES

    Davis, C.; Rozo, E.; Roodman, A.; ...

    2018-03-26

    Galaxy cross-correlations with high-fidelity redshift samples hold the potential to precisely calibrate systematic photometric redshift uncertainties arising from the unavailability of complete and representative training and validation samples of galaxies. However, application of this technique in the Dark Energy Survey (DES) is hampered by the relatively low number density, small area, and modest redshift overlap between photometric and spectroscopic samples. We propose instead using photometric catalogs with reliable photometric redshifts for photo-z calibration via cross-correlations. We verify the viability of our proposal using redMaPPer clusters from the Sloan Digital Sky Survey (SDSS) to successfully recover the redshift distribution of SDSS spectroscopic galaxies. We demonstrate how to combine photo-z with cross-correlation data to calibrate photometric redshift biases while marginalizing over possible clustering bias evolution in either the calibration or unknown photometric samples. We apply our method to DES Science Verification (DES SV) data in order to constrain the photometric redshift distribution of a galaxy sample selected for weak lensing studies, constraining the mean of the tomographic redshift distributions to a statistical uncertainty ofmore » $$\\Delta z \\sim \\pm 0.01$$. We forecast that our proposal can in principle control photometric redshift uncertainties in DES weak lensing experiments at a level near the intrinsic statistical noise of the experiment over the range of redshifts where redMaPPer clusters are available. Here, our results provide strong motivation to launch a program to fully characterize the systematic errors from bias evolution and photo-z shapes in our calibration procedure.« less

  12. Cross-correlation redshift calibration without spectroscopic calibration samples in DES Science Verification Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davis, C.; Rozo, E.; Roodman, A.

    Galaxy cross-correlations with high-fidelity redshift samples hold the potential to precisely calibrate systematic photometric redshift uncertainties arising from the unavailability of complete and representative training and validation samples of galaxies. However, application of this technique in the Dark Energy Survey (DES) is hampered by the relatively low number density, small area, and modest redshift overlap between photometric and spectroscopic samples. We propose instead using photometric catalogs with reliable photometric redshifts for photo-z calibration via cross-correlations. We verify the viability of our proposal using redMaPPer clusters from the Sloan Digital Sky Survey (SDSS) to successfully recover the redshift distribution of SDSS spectroscopic galaxies. We demonstrate how to combine photo-z with cross-correlation data to calibrate photometric redshift biases while marginalizing over possible clustering bias evolution in either the calibration or unknown photometric samples. We apply our method to DES Science Verification (DES SV) data in order to constrain the photometric redshift distribution of a galaxy sample selected for weak lensing studies, constraining the mean of the tomographic redshift distributions to a statistical uncertainty ofmore » $$\\Delta z \\sim \\pm 0.01$$. We forecast that our proposal can in principle control photometric redshift uncertainties in DES weak lensing experiments at a level near the intrinsic statistical noise of the experiment over the range of redshifts where redMaPPer clusters are available. Here, our results provide strong motivation to launch a program to fully characterize the systematic errors from bias evolution and photo-z shapes in our calibration procedure.« less

  13. Property-driven functional verification technique for high-speed vision system-on-chip processor

    NASA Astrophysics Data System (ADS)

    Nshunguyimfura, Victor; Yang, Jie; Liu, Liyuan; Wu, Nanjian

    2017-04-01

    The implementation of functional verification in a fast, reliable, and effective manner is a challenging task in a vision chip verification process. The main reason for this challenge is the stepwise nature of existing functional verification techniques. This vision chip verification complexity is also related to the fact that in most vision chip design cycles, extensive efforts are focused on how to optimize chip metrics such as performance, power, and area. Design functional verification is not explicitly considered at an earlier stage at which the most sound decisions are made. In this paper, we propose a semi-automatic property-driven verification technique. The implementation of all verification components is based on design properties. We introduce a low-dimension property space between the specification space and the implementation space. The aim of this technique is to speed up the verification process for high-performance parallel processing vision chips. Our experimentation results show that the proposed technique can effectively improve the verification effort up to 20% for the complex vision chip design while reducing the simulation and debugging overheads.

  14. VERIFICATION TESTING OF HIGH-RATE MECHANICAL INDUCTION MIXERS FOR CHEMICAL DISINFECTANTS

    EPA Science Inventory

    This paper describes the results of verification testing of mechanical induction mixers for dispersion of chemical disinfectants in wet-weather flow (WWF) conducted under the U.S. Environmental Protection Agency's Environmental Technology Verification (ETV) WWF Pilot Program. Th...

  15. UAS in the NAS Project: Large-Scale Communication Architecture Simulations with NASA GRC Gen5 Radio Model

    NASA Technical Reports Server (NTRS)

    Kubat, Gregory

    2016-01-01

    This report provides a description and performance characterization of the large-scale, Relay architecture, UAS communications simulation capability developed for the NASA GRC, UAS in the NAS Project. The system uses a validated model of the GRC Gen5 CNPC, Flight-Test Radio model. Contained in the report is a description of the simulation system and its model components, recent changes made to the system to improve performance, descriptions and objectives of sample simulations used for test and verification, and a sampling and observations of results and performance data.

  16. Exploration of Uncertainty in Glacier Modelling

    NASA Technical Reports Server (NTRS)

    Thompson, David E.

    1999-01-01

    There are procedures and methods for verification of coding algebra and for validations of models and calculations that are in use in the aerospace computational fluid dynamics (CFD) community. These methods would be efficacious if used by the glacier dynamics modelling community. This paper is a presentation of some of those methods, and how they might be applied to uncertainty management supporting code verification and model validation for glacier dynamics. The similarities and differences between their use in CFD analysis and the proposed application of these methods to glacier modelling are discussed. After establishing sources of uncertainty and methods for code verification, the paper looks at a representative sampling of verification and validation efforts that are underway in the glacier modelling community, and establishes a context for these within overall solution quality assessment. Finally, an information architecture and interactive interface is introduced and advocated. This Integrated Cryospheric Exploration (ICE) Environment is proposed for exploring and managing sources of uncertainty in glacier modelling codes and methods, and for supporting scientific numerical exploration and verification. The details and functionality of this Environment are described based on modifications of a system already developed for CFD modelling and analysis.

  17. Thermal Protection for Mars Sample Return Earth Entry Vehicle: A Grand Challenge for Design Methodology and Reliability Verification

    NASA Technical Reports Server (NTRS)

    Venkatapathy, Ethiraj; Gage, Peter; Wright, Michael J.

    2017-01-01

    Mars Sample Return is our Grand Challenge for the coming decade. TPS (Thermal Protection System) nominal performance is not the key challenge. The main difficulty for designers is the need to verify unprecedented reliability for the entry system: current guidelines for prevention of backward contamination require that the probability of spores larger than 1 micron diameter escaping into the Earth environment be lower than 1 million for the entire system, and the allocation to TPS would be more stringent than that. For reference, the reliability allocation for Orion TPS is closer to 11000, and the demonstrated reliability for previous human Earth return systems was closer to 1100. Improving reliability by more than 3 orders of magnitude is a grand challenge indeed. The TPS community must embrace the possibility of new architectures that are focused on reliability above thermal performance and mass efficiency. MSR (Mars Sample Return) EEV (Earth Entry Vehicle) will be hit with MMOD (Micrometeoroid and Orbital Debris) prior to reentry. A chute-less aero-shell design which allows for self-righting shape was baselined in prior MSR studies, with the assumption that a passive system will maximize EEV robustness. Hence the aero-shell along with the TPS has to take ground impact and not break apart. System verification will require testing to establish ablative performance and thermal failure but also testing of damage from MMOD, and structural performance at ground impact. Mission requirements will demand analysis, testing and verification that are focused on establishing reliability of the design. In this proposed talk, we will focus on the grand challenge of MSR EEV TPS and the need for innovative approaches to address challenges in modeling, testing, manufacturing and verification.

  18. 40 CFR 1065.925 - PEMS preparation for field testing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... 1065.925 Section 1065.925 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... purge any gaseous sampling PEMS instruments with ambient air until sampling begins to prevent system contamination from excessive cold-start emissions. (e) Conduct calibrations and verifications. (f) Operate any...

  19. ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) TEST OF DIOXIN EMISSION MONITORS

    EPA Science Inventory

    The performance of four dioxin emission monitors including two long-term sampling devices, the DMS (DioxinMonitoringSystem) and AMESA (Adsorption Method for Sampling Dioxins and Furans), and two semi-real-time continuous monitors, RIMMPA-TOFMS (Resonance Ionization with Multi-Mir...

  20. Plasma protein absolute quantification by nano-LC Q-TOF UDMSE for clinical biomarker verification

    PubMed Central

    ILIES, MARIA; IUGA, CRISTINA ADELA; LOGHIN, FELICIA; DHOPLE, VISHNU MUKUND; HAMMER, ELKE

    2017-01-01

    Background and aims Proteome-based biomarker studies are targeting proteins that could serve as diagnostic, prognosis, and prediction molecules. In the clinical routine, immunoassays are currently used for the absolute quantification of such biomarkers, with the major limitation that only one molecule can be targeted per assay. The aim of our study was to test a mass spectrometry based absolute quantification method for the verification of plasma protein sets which might serve as reliable biomarker panels for the clinical practice. Methods Six EDTA plasma samples were analyzed after tryptic digestion using a high throughput data independent acquisition nano-LC Q-TOF UDMSE proteomics approach. Synthetic Escherichia coli standard peptides were spiked in each sample for the absolute quantification. Data analysis was performed using ProgenesisQI v2.0 software (Waters Corporation). Results Our method ensured absolute quantification of 242 non redundant plasma proteins in a single run analysis. The dynamic range covered was 105. 86% were represented by classical plasma proteins. The overall median coefficient of variation was 0.36, while a set of 63 proteins was found to be highly stable. Absolute protein concentrations strongly correlated with values reviewed in the literature. Conclusions Nano-LC Q-TOF UDMSE proteomic analysis can be used for a simple and rapid determination of absolute amounts of plasma proteins. A large number of plasma proteins could be analyzed, while a wide dynamic range was covered with low coefficient of variation at protein level. The method proved to be a reliable tool for the quantification of protein panel for biomarker verification in the clinical practice. PMID:29151793

  1. Landing System Development- Design and Test Prediction of a Lander Leg Using Nonlinear Analysis

    NASA Astrophysics Data System (ADS)

    Destefanis, Stefano; Buchwald, Robert; Pellegrino, Pasquale; Schroder, Silvio

    2014-06-01

    Several mission studies have been performed focusing on a soft and precision landing using landing legs. Examples for such missions are Mars Sample Return scenarios (MSR), Lunar landing scenarios (MoonNEXT, Lunar Lander) and small body sample return studies (Marco Polo, MMSR, Phootprint). Such missions foresee a soft landing on the planet surface for delivering payload in a controlled manner and limiting the landing loads.To ensure a successful final landing phase, a landing system is needed, capable of absorbing the residual velocities (vertical, horizontal and angular) at touch- down, and insuring a controlled attitude after landing. Such requirements can be fulfilled by using landing legs with adequate damping.The Landing System Development (LSD) study, currently in its phase 2, foresees the design, analysis, verification, manufacturing and testing of a representative landing leg breadboard based on the Phase B design of the ESA Lunar Lander. Drop tests of a single leg will be performed both on rigid and soft ground, at several impact angles. The activity is covered under ESA contract with TAS-I as Prime Contractor, responsible for analysis and verification, Astrium GmbH for design and test and QinetiQ Space for manufacturing. Drop tests will be performed at the Institute of Space Systems of the German Aerospace Center (DLR-RY) in Bremen.This paper presents an overview of the analytical simulations (test predictions and design verification) performed, comparing the results produced by Astrium made multi body model (rigid bodies, nonlinearities accounted for in mechanical joints and force definitions, based on development tests) and TAS-I made nonlinear explicit model (fully deformable bodies).

  2. Self-verification and depression among youth psychiatric inpatients.

    PubMed

    Joiner, T E; Katz, J; Lew, A S

    1997-11-01

    According to self-verification theory (e.g., W.B. Swann, 1983), people are motivated to preserve stable self-concepts by seeking self-confirming interpersonal responses, even if the responses are negative. In the current study of 72 youth psychiatric inpatients (36 boys; 36 girls; ages 7-17, M = 13.18; SD = 2.59), the authors provide the 1st test of self-verification theory among a youth sample. Participants completed self-report questionnaires on depression, self-esteem, anxiety, negative and positive affect, and interest in negative feedback from others. The authors made chart diagnoses available, and they collected peer rejection ratings. Consistent with hypotheses, the authors found that interest in negative feedback was associated with depression, was predictive of peer rejection (but only within relatively longer peer relationships), was more highly related to cognitive than emotional aspects of depression, and was specifically associated with depression, rather than being generally associated with emotional distress. The authors discuss implications for self-verification theory and for the phenomenology of youth depression.

  3. Improved Hip-Based Individual Recognition Using Wearable Motion Recording Sensor

    NASA Astrophysics Data System (ADS)

    Gafurov, Davrondzhon; Bours, Patrick

    In todays society the demand for reliable verification of a user identity is increasing. Although biometric technologies based on fingerprint or iris can provide accurate and reliable recognition performance, they are inconvenient for periodic or frequent re-verification. In this paper we propose a hip-based user recognition method which can be suitable for implicit and periodic re-verification of the identity. In our approach we use a wearable accelerometer sensor attached to the hip of the person, and then the measured hip motion signal is analysed for identity verification purposes. The main analyses steps consists of detecting gait cycles in the signal and matching two sets of detected gait cycles. Evaluating the approach on a hip data set consisting of 400 gait sequences (samples) from 100 subjects, we obtained equal error rate (EER) of 7.5% and identification rate at rank 1 was 81.4%. These numbers are improvements by 37.5% and 11.2% respectively of the previous study using the same data set.

  4. Development and verification of a model for estimating the screening utility in the detection of PCBs in transformer oil.

    PubMed

    Terakado, Shingo; Glass, Thomas R; Sasaki, Kazuhiro; Ohmura, Naoya

    2014-01-01

    A simple new model for estimating the screening performance (false positive and false negative rates) of a given test for a specific sample population is presented. The model is shown to give good results on a test population, and is used to estimate the performance on a sampled population. Using the model developed in conjunction with regulatory requirements and the relative costs of the confirmatory and screening tests allows evaluation of the screening test's utility in terms of cost savings. Testers can use the methods developed to estimate the utility of a screening program using available screening tests with their own sample populations.

  5. VERIFICATION TESTING OF HIGH-RATE MECHANICAL INDUCTION MIXERS FOR CHEMICAL DISINFECTANTS, Oregon

    EPA Science Inventory

    This paper describes the results of verification testing of mechanical induction mixers for dispersion of chemical disinfectants in wet-weather flow (WWF) conducted under the U.S. Environmental Protection Agency's Environmental Technology Verification (ETV) WWF Pilot Program. Th...

  6. Certification and verification for Calmac flat plate solar collector

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Information used in the certification and verification of the Calmac Flat Plate Collector is presented. Contained are such items as test procedures and results, information on materials used, installation, operation, and maintenance manuals, and other information pertaining to the verification and certification.

  7. Statistical analysis of NWP rainfall data from Poland..

    NASA Astrophysics Data System (ADS)

    Starosta, Katarzyna; Linkowska, Joanna

    2010-05-01

    A goal of this work is to summarize the latest results of precipitation verification in Poland. In IMGW, COSMO_PL version 4.0 has been running. The model configuration is: 14 km horizontal grid spacing, initial time at 00 UTC and 12 UTC, the forecast range 72 h. The fields from the model had been verified with Polish SYNOP stations. The verification was performed using a new verification tool. For the accumulated precipitation indices FBI, POD, FAR, ETS from contingency table are calculated. In this paper the comparison of monthly and seasonal verification of 6h, 12h, 24h accumulated precipitation in 2009 is presented. Since February 2010 the model with 7 km grid spacing will be running in IMGW. The results of precipitation verification for two different models' resolution will be shown.

  8. Exploring implementation practices in results-based financing: the case of the verification in Benin.

    PubMed

    Antony, Matthieu; Bertone, Maria Paola; Barthes, Olivier

    2017-03-14

    Results-based financing (RBF) has been introduced in many countries across Africa and a growing literature is building around the assessment of their impact. These studies are usually quantitative and often silent on the paths and processes through which results are achieved and on the wider health system effects of RBF. To address this gap, our study aims at exploring the implementation of an RBF pilot in Benin, focusing on the verification of results. The study is based on action research carried out by authors involved in the pilot as part of the agency supporting the RBF implementation in Benin. While our participant observation and operational collaboration with project's stakeholders informed the study, the analysis is mostly based on quantitative and qualitative secondary data, collected throughout the project's implementation and documentation processes. Data include project documents, reports and budgets, RBF data on service outputs and on the outcome of the verification, daily activity timesheets of the technical assistants in the districts, as well as focus groups with Community-based Organizations and informal interviews with technical assistants and district medical officers. Our analysis focuses on the actual practices of quantitative, qualitative and community verification. Results show that the verification processes are complex, costly and time-consuming, and in practice they end up differing from what designed originally. We explore the consequences of this on the operation of the scheme, on its potential to generate the envisaged change. We find, for example, that the time taken up by verification procedures limits the time available for data analysis and feedback to facility staff, thus limiting the potential to improve service delivery. Verification challenges also result in delays in bonus payment, which delink effort and reward. Additionally, the limited integration of the verification activities of district teams with their routine tasks causes a further verticalization of the health system. Our results highlight the potential disconnect between the theory of change behind RBF and the actual scheme's implementation. The implications are relevant at methodological level, stressing the importance of analyzing implementation processes to fully understand results, as well as at operational level, pointing to the need to carefully adapt the design of RBF schemes (including verification and other key functions) to the context and to allow room to iteratively modify it during implementation. They also question whether the rationale for thorough and costly verification is justified, or rather adaptations are possible.

  9. Height-resolved large-sample INAA of a 1 m long, 13 cm diameter ditch-bottom sample

    NASA Astrophysics Data System (ADS)

    Blaauw, M.; Baas, H. W.; Donze, M.

    2003-06-01

    A facility for instrumental neutron activation analysis (INAA) of large samples (up to 1 m long and 15 cm diameter) has been built. Correction methods for the simultaneous occurrence of neutron self-shielding and gamma-ray self-attenuation effects have been implemented and tested with a variety of samples. Now, the method has been extended to allow for the interpretation of scanned, collimated measurements, where results are obtained for individual voxels. As a validation and demonstration, a ditch-bottom sample of the maximum size was taken in a frozen condition. It was cut in 2 cm slices, still frozen, and put together again with each slice in a 2 cm height Petri dish divided in three sections. This allowed for verification of the results by ordinary INAA. Possible explanations for the discrepancies we observed between ordinary and large-sample INAA in the region where the concentration gradients are the steepest are discussed.

  10. On marker-based parentage verification via non-linear optimization.

    PubMed

    Boerner, Vinzent

    2017-06-15

    Parentage verification by molecular markers is mainly based on short tandem repeat markers. Single nucleotide polymorphisms (SNPs) as bi-allelic markers have become the markers of choice for genotyping projects. Thus, the subsequent step is to use SNP genotypes for parentage verification as well. Recent developments of algorithms such as evaluating opposing homozygous SNP genotypes have drawbacks, for example the inability of rejecting all animals of a sample of potential parents. This paper describes an algorithm for parentage verification by constrained regression which overcomes the latter limitation and proves to be very fast and accurate even when the number of SNPs is as low as 50. The algorithm was tested on a sample of 14,816 animals with 50, 100 and 500 SNP genotypes randomly selected from 40k genotypes. The samples of putative parents of these animals contained either five random animals, or four random animals and the true sire. Parentage assignment was performed by ranking of regression coefficients, or by setting a minimum threshold for regression coefficients. The assignment quality was evaluated by the power of assignment (P[Formula: see text]) and the power of exclusion (P[Formula: see text]). If the sample of putative parents contained the true sire and parentage was assigned by coefficient ranking, P[Formula: see text] and P[Formula: see text] were both higher than 0.99 for the 500 and 100 SNP genotypes, and higher than 0.98 for the 50 SNP genotypes. When parentage was assigned by a coefficient threshold, P[Formula: see text] was higher than 0.99 regardless of the number of SNPs, but P[Formula: see text] decreased from 0.99 (500 SNPs) to 0.97 (100 SNPs) and 0.92 (50 SNPs). If the sample of putative parents did not contain the true sire and parentage was rejected using a coefficient threshold, the algorithm achieved a P[Formula: see text] of 1 (500 SNPs), 0.99 (100 SNPs) and 0.97 (50 SNPs). The algorithm described here is easy to implement, fast and accurate, and is able to assign parentage using genomic marker data with a size as low as 50 SNPs.

  11. Generic Verification Protocol for Testing Pesticide Application Spray Drift Reduction Technologies for Row and Field Crops

    EPA Pesticide Factsheets

    This generic verification protocol provides a detailed method to conduct and report results from a verification test of pesticide application technologies that can be used to evaluate these technologies for their potential to reduce spray drift.

  12. SITE CHARACTERIZATION AND MONITORING TECHNOLOGY VERIFICATION: PROGRESS AND RESULTS

    EPA Science Inventory

    The Site Characterization and Monitoring Technology Pilot of the U.S. Environmental Protection Agency's Environmental Technology Verification Program (ETV) has been engaged in verification activities since the fall of 1994 (U.S. EPA, 1997). The purpose of the ETV is to promote th...

  13. Validation of mesoscale models

    NASA Technical Reports Server (NTRS)

    Kuo, Bill; Warner, Tom; Benjamin, Stan; Koch, Steve; Staniforth, Andrew

    1993-01-01

    The topics discussed include the following: verification of cloud prediction from the PSU/NCAR mesoscale model; results form MAPS/NGM verification comparisons and MAPS observation sensitivity tests to ACARS and profiler data; systematic errors and mesoscale verification for a mesoscale model; and the COMPARE Project and the CME.

  14. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT--BAGHOUSE FILTRATION PRODUCTS, W.L. GORE ASSOC., INC.

    EPA Science Inventory

    The U.S. Environmental Protection Agency Air Pollution Control Technology (APCT) Verification Center evaluates the performance of baghouse filtration products used primarily to control PM2.5 emissions. This verification statement summarizes the test results for W.L. Gore & Assoc....

  15. On Biometrics With Eye Movements.

    PubMed

    Zhang, Youming; Juhola, Martti

    2017-09-01

    Eye movements are a relatively novel data source for biometric identification. When video cameras applied to eye tracking become smaller and more efficient, this data source could offer interesting opportunities for the development of eye movement biometrics. In this paper, we study primarily biometric identification as seen as a classification task of multiple classes, and secondarily biometric verification considered as binary classification. Our research is based on the saccadic eye movement signal measurements from 109 young subjects. In order to test the data measured, we use a procedure of biometric identification according to the one-versus-one (subject) principle. In a development from our previous research, which also involved biometric verification based on saccadic eye movements, we now apply another eye movement tracker device with a higher sampling frequency of 250 Hz. The results obtained are good, with correct identification rates at 80-90% at their best.

  16. Soil Gas Sample Handling: Evaluation of Water Removal and Sample Ganging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fritz, Brad G.; Abrecht, David G.; Hayes, James C.

    2016-10-31

    Soil gas sampling is currently conducted in support of Nuclear Test Ban treaty verification. Soil gas samples are collected and analyzed for isotopes of interest. Some issues that can impact sampling and analysis of these samples are excess moisture and sample processing time. Here we discuss three potential improvements to the current sampling protocol; a desiccant for water removal, use of molecular sieve to remove CO 2 from the sample during collection, and a ganging manifold to allow composite analysis of multiple samples.

  17. Accurate Biomass Estimation via Bayesian Adaptive Sampling

    NASA Technical Reports Server (NTRS)

    Wheeler, Kevin R.; Knuth, Kevin H.; Castle, Joseph P.; Lvov, Nikolay

    2005-01-01

    The following concepts were introduced: a) Bayesian adaptive sampling for solving biomass estimation; b) Characterization of MISR Rahman model parameters conditioned upon MODIS landcover. c) Rigorous non-parametric Bayesian approach to analytic mixture model determination. d) Unique U.S. asset for science product validation and verification.

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holmes, J.P.; Maxwell, R.L.; Wright, L.J.

    A biometric identification device is an automatic device that can verify a person's identity from a measurement of a physical feature or repeatable action of the individual. A reference measurement of the biometric is obtained when the individual is enrolled on the device. Subsequent verifications are made by comparing the submitted biometric feature against the reference sample. Sandia Laboratories has been evaluating the relative performance of several identity verifiers, using volunteer test subjects. Sandia testing methods and results are discussed.

  19. Validation of 15 kGy as a radiation sterilisation dose for bone allografts manufactured at the Queensland Bone Bank: application of the VDmax 15 method.

    PubMed

    Nguyen, Huynh; Morgan, David A F; Sly, Lindsay I; Benkovich, Morris; Cull, Sharon; Forwood, Mark R

    2008-06-01

    ISO 11137-2006 (ISO 11137-2a 2006) provides a VDmax 15 method for substantiation of 15 kGy as radiation sterilisation dose (RSD) for health care products with a relatively low sample requirement. Moreover, the method is also valid for products in which the bioburden level is less than or equal to 1.5. In the literature, the bioburden level of processed bone allografts is extremely low. Similarly, the Queensland Bone Bank (QBB) usually recovers no viable organisms from processed bone allografts. Because bone allografts are treated as a type of health care product, the aim of this research was to substantiate 15 kGy as a RSD for frozen bone allografts at the QBB using method VDmax 15-ISO 11137-2: 2006 (ISO 11137-2e, Procedure for method VDmax 15 for multiple production batches. Sterilisation of health care products - radiation - part 2: establishing the sterilisation dose, 2006; ISO 11137-2f, Procedure for method VDmax 15 for a single production batch. Sterilisation of health care products - radiation - part 2: establishing the sterilisation dose, 2006). 30 femoral heads, 40 milled bone allografts and 40 structural bone allografts manufactured according to QBB standard operating procedures were used. Estimated bioburdens for each bone allograft group were used to calculate the verification doses. Next, 10 samples per group were irradiated at the verification dose, sterility was tested and the number of positive tests of sterility recorded. If the number of positive samples was no more than 1, from the 10 tests carried out in each group, the verification was accepted and 15 kGy was substantiated as RSD for those bone allografts. The bioburdens in all three groups were 0, and therefore the verification doses were 0 kGy. Sterility tests of femoral heads and milled bones were all negative (no contamination), and there was one positive test of sterility in the structural bone allograft. Accordingly, the verification was accepted. Using the ISO validated protocol, VDmax 15, 15 kGy was substantiated as RSD for frozen bone allografts manufactured at the QBB.

  20. Magnetic cleanliness verification approach on tethered satellite

    NASA Technical Reports Server (NTRS)

    Messidoro, Piero; Braghin, Massimo; Grande, Maurizio

    1990-01-01

    Magnetic cleanliness testing was performed on the Tethered Satellite as the last step of an articulated verification campaign aimed at demonstrating the capability of the satellite to support its TEMAG (TEthered MAgnetometer) experiment. Tests at unit level and analytical predictions/correlations using a dedicated mathematical model (GANEW program) are also part of the verification activities. Details of the tests are presented, and the results of the verification are described together with recommendations for later programs.

  1. Compromises produced by the dialectic between self-verification and self-enhancement.

    PubMed

    Morling, B; Epstein, S

    1997-12-01

    Three studies of people's reactions to evaluative feedback demonstrated that the dialectic between self-enhancement and self-verification results in compromises between these 2 motives, as hypothesized in cognitive-experiential self-theory. The demonstration was facilitated by 2 procedural improvements: Enhancement and verification were established by calibrating evaluative feedback against self appraisals, and degree of enhancement and of verification were varied along a continuum, rather than categorically. There was also support for the hypotheses that processing in an intuitive-experiential mode favors enhancement and processing in an analytical-rational mode favors verification in the kinds of situations investigated.

  2. Enhanced Verification Test Suite for Physics Simulation Codes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kamm, J R; Brock, J S; Brandon, S T

    2008-10-10

    This document discusses problems with which to augment, in quantity and in quality, the existing tri-laboratory suite of verification problems used by Los Alamos National Laboratory (LANL), Lawrence Livermore National Laboratory (LLNL), and Sandia National Laboratories (SNL). The purpose of verification analysis is demonstrate whether the numerical results of the discretization algorithms in physics and engineering simulation codes provide correct solutions of the corresponding continuum equations. The key points of this document are: (1) Verification deals with mathematical correctness of the numerical algorithms in a code, while validation deals with physical correctness of a simulation in a regime of interest.more » This document is about verification. (2) The current seven-problem Tri-Laboratory Verification Test Suite, which has been used for approximately five years at the DOE WP laboratories, is limited. (3) Both the methodology for and technology used in verification analysis have evolved and been improved since the original test suite was proposed. (4) The proposed test problems are in three basic areas: (a) Hydrodynamics; (b) Transport processes; and (c) Dynamic strength-of-materials. (5) For several of the proposed problems we provide a 'strong sense verification benchmark', consisting of (i) a clear mathematical statement of the problem with sufficient information to run a computer simulation, (ii) an explanation of how the code result and benchmark solution are to be evaluated, and (iii) a description of the acceptance criterion for simulation code results. (6) It is proposed that the set of verification test problems with which any particular code be evaluated include some of the problems described in this document. Analysis of the proposed verification test problems constitutes part of a necessary--but not sufficient--step that builds confidence in physics and engineering simulation codes. More complicated test cases, including physics models of greater sophistication or other physics regimes (e.g., energetic material response, magneto-hydrodynamics), would represent a scientifically desirable complement to the fundamental test cases discussed in this report. The authors believe that this document can be used to enhance the verification analyses undertaken at the DOE WP Laboratories and, thus, to improve the quality, credibility, and usefulness of the simulation codes that are analyzed with these problems.« less

  3. Research on key technology of the verification system of steel rule based on vision measurement

    NASA Astrophysics Data System (ADS)

    Jia, Siyuan; Wang, Zhong; Liu, Changjie; Fu, Luhua; Li, Yiming; Lu, Ruijun

    2018-01-01

    The steel rule plays an important role in quantity transmission. However, the traditional verification method of steel rule based on manual operation and reading brings about low precision and low efficiency. A machine vison based verification system of steel rule is designed referring to JJG1-1999-Verificaiton Regulation of Steel Rule [1]. What differentiates this system is that it uses a new calibration method of pixel equivalent and decontaminates the surface of steel rule. Experiments show that these two methods fully meet the requirements of the verification system. Measuring results strongly prove that these methods not only meet the precision of verification regulation, but also improve the reliability and efficiency of the verification system.

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Peters, T. B.; Bannochie, C. J.

    Savannah River National Laboratory (SRNL) analyzed samples from Tank 21H in support of verification of Macrobatch (Salt Batch) 11 for the Interim Salt Disposition Program (ISDP) for processing. This document reports characterization data on the samples of Tank 21H and fulfills the requirements of Deliverable 3 of the Technical Task Request (TTR).

  5. Verification and Validation Studies for the LAVA CFD Solver

    NASA Technical Reports Server (NTRS)

    Moini-Yekta, Shayan; Barad, Michael F; Sozer, Emre; Brehm, Christoph; Housman, Jeffrey A.; Kiris, Cetin C.

    2013-01-01

    The verification and validation of the Launch Ascent and Vehicle Aerodynamics (LAVA) computational fluid dynamics (CFD) solver is presented. A modern strategy for verification and validation is described incorporating verification tests, validation benchmarks, continuous integration and version control methods for automated testing in a collaborative development environment. The purpose of the approach is to integrate the verification and validation process into the development of the solver and improve productivity. This paper uses the Method of Manufactured Solutions (MMS) for the verification of 2D Euler equations, 3D Navier-Stokes equations as well as turbulence models. A method for systematic refinement of unstructured grids is also presented. Verification using inviscid vortex propagation and flow over a flat plate is highlighted. Simulation results using laminar and turbulent flow past a NACA 0012 airfoil and ONERA M6 wing are validated against experimental and numerical data.

  6. Optimal approaches for inline sampling of organisms in ballast water: L-shaped vs. Straight sample probes

    NASA Astrophysics Data System (ADS)

    Wier, Timothy P.; Moser, Cameron S.; Grant, Jonathan F.; Riley, Scott C.; Robbins-Wamsley, Stephanie H.; First, Matthew R.; Drake, Lisa A.

    2017-10-01

    Both L-shaped ("L") and straight ("Straight") sample probes have been used to collect water samples from a main ballast line in land-based or shipboard verification testing of ballast water management systems (BWMS). A series of experiments was conducted to quantify and compare the sampling efficiencies of L and Straight sample probes. The findings from this research-that both L and Straight probes sample organisms with similar efficiencies-permit increased flexibility for positioning sample probes aboard ships.

  7. A verification library for multibody simulation software

    NASA Technical Reports Server (NTRS)

    Kim, Sung-Soo; Haug, Edward J.; Frisch, Harold P.

    1989-01-01

    A multibody dynamics verification library, that maintains and manages test and validation data is proposed, based on RRC Robot arm and CASE backhoe validation and a comparitive study of DADS, DISCOS, and CONTOPS that are existing public domain and commercial multibody dynamic simulation programs. Using simple representative problems, simulation results from each program are cross checked, and the validation results are presented. Functionalities of the verification library are defined, in order to automate validation procedure.

  8. Development of an inpatient operational pharmacy productivity model.

    PubMed

    Naseman, Ryan W; Lopez, Ben R; Forrey, Ryan A; Weber, Robert J; Kipp, Kris M

    2015-02-01

    An innovative model for measuring the operational productivity of medication order management in inpatient settings is described. Order verification within a computerized prescriber order-entry system was chosen as the pharmacy workload driver. To account for inherent variability in the tasks involved in processing different types of orders, pharmaceutical products were grouped by class, and each class was assigned a time standard, or "medication complexity weight" reflecting the intensity of pharmacist and technician activities (verification of drug indication, verification of appropriate dosing, adverse-event prevention and monitoring, medication preparation, product checking, product delivery, returns processing, nurse/provider education, and problem-order resolution). The resulting "weighted verifications" (WV) model allows productivity monitoring by job function (pharmacist versus technician) to guide hiring and staffing decisions. A 9-month historical sample of verified medication orders was analyzed using the WV model, and the calculations were compared with values derived from two established models—one based on the Case Mix Index (CMI) and the other based on the proprietary Pharmacy Intensity Score (PIS). Evaluation of Pearson correlation coefficients indicated that values calculated using the WV model were highly correlated with those derived from the CMI-and PIS-based models (r = 0.845 and 0.886, respectively). Relative to the comparator models, the WV model offered the advantage of less period-to-period variability. The WV model yielded productivity data that correlated closely with values calculated using two validated workload management models. The model may be used as an alternative measure of pharmacy operational productivity. Copyright © 2015 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  9. Towards the development of a rapid, portable, surface enhanced Raman spectroscopy based cleaning verification system for the drug nelarabine.

    PubMed

    Corrigan, Damion K; Salton, Neale A; Preston, Chris; Piletsky, Sergey

    2010-09-01

    Cleaning verification is a scientific and economic problem for the pharmaceutical industry. A large amount of potential manufacturing time is lost to the process of cleaning verification. This involves the analysis of residues on spoiled manufacturing equipment, with high-performance liquid chromatography (HPLC) being the predominantly employed analytical technique. The aim of this study was to develop a portable cleaning verification system for nelarabine using surface enhanced Raman spectroscopy (SERS). SERS was conducted using a portable Raman spectrometer and a commercially available SERS substrate to develop a rapid and portable cleaning verification system for nelarabine. Samples of standard solutions and swab extracts were deposited onto the SERS active surfaces, allowed to dry and then subjected to spectroscopic analysis. Nelarabine was amenable to analysis by SERS and the necessary levels of sensitivity were achievable. It is possible to use this technology for a semi-quantitative limits test. Replicate precision, however, was poor due to the heterogeneous drying pattern of nelarabine on the SERS active surface. Understanding and improving the drying process in order to produce a consistent SERS signal for quantitative analysis is desirable. This work shows the potential application of SERS for cleaning verification analysis. SERS may not replace HPLC as the definitive analytical technique, but it could be used in conjunction with HPLC so that swabbing is only carried out once the portable SERS equipment has demonstrated that the manufacturing equipment is below the threshold contamination level.

  10. A Practitioners Perspective on Verification

    NASA Astrophysics Data System (ADS)

    Steenburgh, R. A.

    2017-12-01

    NOAAs Space Weather Prediction Center offers a wide range of products and services to meet the needs of an equally wide range of customers. A robust verification program is essential to the informed use of model guidance and other tools by both forecasters and end users alike. In this talk, we present current SWPC practices and results, and examine emerging requirements and potential approaches to satisfy them. We explore the varying verification needs of forecasters and end users, as well as the role of subjective and objective verification. Finally, we describe a vehicle used in the meteorological community to unify approaches to model verification and facilitate intercomparison.

  11. Verification of intravenous catheter placement by auscultation--a simple, noninvasive technique.

    PubMed

    Lehavi, Amit; Rudich, Utay; Schechtman, Moshe; Katz, Yeshayahu Shai

    2014-01-01

    Verification of proper placement of an intravenous catheter may not always be simple. We evaluated the auscultation technique for this purpose. Twenty healthy volunteers were randomized for 18G catheter inserted intravenously either in the right (12) or left arm (8), and subcutaneously in the opposite arm. A standard stethoscope was placed over an area approximately 3 cm proximal to the tip of the catheter in the presumed direction of the vein to grade on a 0-6 scale the murmur heard by rapidly injecting 2 mL of NaCl 0.9% solution. The auscultation was evaluated by a blinded staff anesthesiologist. All 20 intravenous injection were evaluated as flow murmurs, and were graded an average 5.65 (±0.98), whereas all 20 subcutaneous injections were evaluated as either crackles or no sound, and were graded an average 2.00 (±1.38), without negative results. Sensitivity was calculated as 95%. Specificity and Kappa could not be calculated due to an empty false-positive group. Being simple, handy and noninvasive, we recommend to use the auscultation technique for verification of the proper placement of an intravenous catheter when uncertain of its position. Data obtained in our limited sample of healthy subjects need to be confirmed in the clinical setting.

  12. AN ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) TESTING OF A TRACEDETECT'S SAFEGUARD METALS ANALYZER FOR ARSENIC

    EPA Science Inventory

    The TraceDetect's SafeGuard is designed to automatically measure total arsenic concentrations in drinking water samples (including raw water and treated water) over a range from 1 ppb to over 100 ppb. Once the operator has introduced the sample vial and selected "measure&qu...

  13. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, PCB DETECTION TECHNOLOGY, HYBRIZYME DELFIA TM ASSAY

    EPA Science Inventory

    The DELFIA PCB Assay is a solid-phase time-resolved fluoroimmunoassay based on the sequential addition of sample extract and europium-labeled PCB tracer to a monoclonal antibody reagent specific for PCBs. In this assay, the antibody reagent and sample extract are added to a strip...

  14. Analytical and Experimental Investigations of Sodium Heat Pipes and Thermal Energy Storage Systems.

    DTIC Science & Technology

    1982-01-01

    continued) Figure Page 5.1 Cylindrical container for eutectic salt (LiF-NgF -KF) . . . . . . 91 5.2 TESC sample . . . . . . ... . . 0...of fluorides of Mg, Li and K. Experimental results have been used to verify the melting point, and latent heat of fusion of the eutectic salt , in...a melting or solidification curve will provide experimental verification for the latent heat value and melting point of a given eutectic salt . In the

  15. 47 CFR 25.132 - Verification of earth station antenna performance standards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Verification of earth station antenna... Verification of earth station antenna performance standards. (a)(1) All applications for transmitting earth... pursuant to § 2.902 of this chapter from the manufacturer of each antenna that the results of a series of...

  16. 47 CFR 25.132 - Verification of earth station antenna performance standards.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 2 2012-10-01 2012-10-01 false Verification of earth station antenna... Verification of earth station antenna performance standards. (a)(1) All applications for transmitting earth... pursuant to § 2.902 of this chapter from the manufacturer of each antenna that the results of a series of...

  17. 47 CFR 25.132 - Verification of earth station antenna performance standards.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false Verification of earth station antenna... Verification of earth station antenna performance standards. (a)(1) All applications for transmitting earth... pursuant to § 2.902 of this chapter from the manufacturer of each antenna that the results of a series of...

  18. Generic Verification Protocol for Testing Pesticide Application Spray Drift Reduction Technologies for Row and Field Crops (Version 1.4)

    EPA Science Inventory

    This generic verification protocol provides a detailed method for conducting and reporting results from verification testing of pesticide application technologies. It can be used to evaluate technologies for their potential to reduce spray drift, hence the term “drift reduction t...

  19. Dosimetric Verification of IMRT Treatment Plans Using an Electronic Portal Imaging Device

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kruszyna, Marta

    This paper presents the procedures and results of dosimetric verification using an Electronic Portal Imaging Device as a tool for pre-treatment dosimetry in IMRT technique at the Greater Poland Cancer Centre in Poznan, Poland. The evaluation of dosimetric verification for various organ, during a 2 year period is given.

  20. Adjusting for partial verification or workup bias in meta-analyses of diagnostic accuracy studies.

    PubMed

    de Groot, Joris A H; Dendukuri, Nandini; Janssen, Kristel J M; Reitsma, Johannes B; Brophy, James; Joseph, Lawrence; Bossuyt, Patrick M M; Moons, Karel G M

    2012-04-15

    A key requirement in the design of diagnostic accuracy studies is that all study participants receive both the test under evaluation and the reference standard test. For a variety of practical and ethical reasons, sometimes only a proportion of patients receive the reference standard, which can bias the accuracy estimates. Numerous methods have been described for correcting this partial verification bias or workup bias in individual studies. In this article, the authors describe a Bayesian method for obtaining adjusted results from a diagnostic meta-analysis when partial verification or workup bias is present in a subset of the primary studies. The method corrects for verification bias without having to exclude primary studies with verification bias, thus preserving the main advantages of a meta-analysis: increased precision and better generalizability. The results of this method are compared with the existing methods for dealing with verification bias in diagnostic meta-analyses. For illustration, the authors use empirical data from a systematic review of studies of the accuracy of the immunohistochemistry test for diagnosis of human epidermal growth factor receptor 2 status in breast cancer patients.

  1. Galaxy bias from galaxy-galaxy lensing in the DES Science Verification Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Prat, J.; et al.

    We present a measurement of galaxy-galaxy lensing around a magnitude-limited (more » $$i_{AB} < 22.5$$) sample of galaxies selected from the Dark Energy Survey Science Verification (DES-SV) data. We split these lenses into three photometric-redshift bins from 0.2 to 0.8, and determine the product of the galaxy bias $b$ and cross-correlation coefficient between the galaxy and dark matter overdensity fields $r$ in each bin, using scales above 4 Mpc/$h$ comoving, where we find the linear bias model to be valid given our current uncertainties. We compare our galaxy bias results from galaxy-galaxy lensing with those obtained from galaxy clustering (Crocce et al. 2016) and CMB lensing (Giannantonio et al. 2016) for the same sample of galaxies, and find our measurements to be in good agreement with those in Crocce et al. (2016), while, in the lowest redshift bin ($$z\\sim0.3$$), they show some tension with the findings in Giannantonio et al. (2016). Our results are found to be rather insensitive to a large range of systematic effects. We measure $$b\\cdot r$$ to be $$0.87\\pm 0.11$$, $$1.12 \\pm 0.16$$ and $$1.24\\pm 0.23$$, respectively for the three redshift bins of width $$\\Delta z = 0.2$$ in the range $0.2« less

  2. 78 FR 53017 - Changes to the Salmonella Verification Sampling Program: Analysis of Raw Beef for Shiga Toxin...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-28

    ... persons to submit comments on this document. Comments may be submitted by one of the following methods... very low (less than one percent), and this carcass sampling was expensive for the Agency. As stated in.... Following the implementation of PR/HACCP, FSIS analyzed only one pathogen per sample. Then, in 2008, FSIS...

  3. Results of the first provisional technical secretariat interlaboratory comparison test

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stuff, J.R.; Hoffland, L.

    1995-06-01

    The principal task of this laboratory in the first Provisional Technical Secretariat (PTS) Interlaboratory Comparison Test was to verify and test the extraction and preparation procedures outlined in the Recommended Operating Procedures for Sampling and Analysis in the Verification of Chemical Disarmament in addition to our laboratory extraction methods and our laboratory analysis methods. Sample preparation began on 16 May 1994 and analysis was completed on 12 June 1994. The analytical methods used included NMR ({sup 1}H and {sup 31}P) GC/AED, GC/MS (EI and methane CI), GC/IRD, HPLC/IC, HPLC/TSP/MS, MS/MS(Electrospray), and CZE.

  4. Quantitative Hydrocarbon Surface Analysis

    NASA Technical Reports Server (NTRS)

    Douglas, Vonnie M.

    2000-01-01

    The elimination of ozone depleting substances, such as carbon tetrachloride, has resulted in the use of new analytical techniques for cleanliness verification and contamination sampling. The last remaining application at Rocketdyne which required a replacement technique was the quantitative analysis of hydrocarbons by infrared spectrometry. This application, which previously utilized carbon tetrachloride, was successfully modified using the SOC-400, a compact portable FTIR manufactured by Surface Optics Corporation. This instrument can quantitatively measure and identify hydrocarbons from solvent flush of hardware as well as directly analyze the surface of metallic components without the use of ozone depleting chemicals. Several sampling accessories are utilized to perform analysis for various applications.

  5. ERLN Biological Focus Area

    EPA Pesticide Factsheets

    The Environmental Response Laboratory Network supports the goal to increase national capacity for biological analysis of environmental samples. This includes methods development and verification, technology transfer, and collaboration with USDA, FERN, CDC.

  6. Compressive sensing using optimized sensing matrix for face verification

    NASA Astrophysics Data System (ADS)

    Oey, Endra; Jeffry; Wongso, Kelvin; Tommy

    2017-12-01

    Biometric appears as one of the solutions which is capable in solving problems that occurred in the usage of password in terms of data access, for example there is possibility in forgetting password and hard to recall various different passwords. With biometrics, physical characteristics of a person can be captured and used in the identification process. In this research, facial biometric is used in the verification process to determine whether the user has the authority to access the data or not. Facial biometric is chosen as its low cost implementation and generate quite accurate result for user identification. Face verification system which is adopted in this research is Compressive Sensing (CS) technique, in which aims to reduce dimension size as well as encrypt data in form of facial test image where the image is represented in sparse signals. Encrypted data can be reconstructed using Sparse Coding algorithm. Two types of Sparse Coding namely Orthogonal Matching Pursuit (OMP) and Iteratively Reweighted Least Squares -ℓp (IRLS-ℓp) will be used for comparison face verification system research. Reconstruction results of sparse signals are then used to find Euclidean norm with the sparse signal of user that has been previously saved in system to determine the validity of the facial test image. Results of system accuracy obtained in this research are 99% in IRLS with time response of face verification for 4.917 seconds and 96.33% in OMP with time response of face verification for 0.4046 seconds with non-optimized sensing matrix, while 99% in IRLS with time response of face verification for 13.4791 seconds and 98.33% for OMP with time response of face verification for 3.1571 seconds with optimized sensing matrix.

  7. Effect of silica-palm shell carbon composite additive in enhancing the strength of the concrete in the oil-well cementing job

    NASA Astrophysics Data System (ADS)

    Novriansyah, A.; Mursyidah, U.; Novrianti; Putri, S. S.; Riswati, S. S.

    2018-04-01

    This study provides an analysis of composite additive effect to concrete’s strength in the oil-well cementing job. The composite additive is originated from the nano-sized form of silica and charcoal from palm shell waste. The quality of the concrete will be determined from its porosity, compressive strength, and shear bond strength parameters. Those parameters must be reliable base on the most respectable standards in oil and gas industry, in this study we use the standard from American Petroleum Institute (API). Six concrete samples with different concentration will be tested to obtain these parameters. The result from the test shown a decrement trend of the porosity while the concentration is increased. In contrast, the highest values of compressive strength and shear bond strength are obtained from the sample with higher additive concentration. The optimum strength was obtained in sample with 0.02% The results become clearly proven through verification by scanning electron image where the additive has successfully fill the voids in the concrete’s sample, resulting in strength enhancement of the sample.

  8. Results from an Independent View on The Validation of Safety-Critical Space Systems

    NASA Astrophysics Data System (ADS)

    Silva, N.; Lopes, R.; Esper, A.; Barbosa, R.

    2013-08-01

    The Independent verification and validation (IV&V) has been a key process for decades, and is considered in several international standards. One of the activities described in the “ESA ISVV Guide” is the independent test verification (stated as Integration/Unit Test Procedures and Test Data Verification). This activity is commonly overlooked since customers do not really see the added value of checking thoroughly the validation team work (could be seen as testing the tester's work). This article presents the consolidated results of a large set of independent test verification activities, including the main difficulties, results obtained and advantages/disadvantages for the industry of these activities. This study will support customers in opting-in or opting-out for this task in future IV&V contracts since we provide concrete results from real case studies in the space embedded systems domain.

  9. Distributed Capacitive Sensor for Sample Mass Measurement

    NASA Technical Reports Server (NTRS)

    Toda, Risaku; McKinney, Colin; Jackson, Shannon P.; Mojarradi, Mohammad; Manohara, Harish; Trebi-Ollennu, Ashitey

    2011-01-01

    Previous robotic sample return missions lacked in situ sample verification/ quantity measurement instruments. Therefore, the outcome of the mission remained unclear until spacecraft return. In situ sample verification systems such as this Distributed Capacitive (DisC) sensor would enable an unmanned spacecraft system to re-attempt the sample acquisition procedures until the capture of desired sample quantity is positively confirmed, thereby maximizing the prospect for scientific reward. The DisC device contains a 10-cm-diameter pressure-sensitive elastic membrane placed at the bottom of a sample canister. The membrane deforms under the weight of accumulating planetary sample. The membrane is positioned in close proximity to an opposing rigid substrate with a narrow gap. The deformation of the membrane makes the gap narrower, resulting in increased capacitance between the two parallel plates (elastic membrane and rigid substrate). C-V conversion circuits on a nearby PCB (printed circuit board) provide capacitance readout via LVDS (low-voltage differential signaling) interface. The capacitance method was chosen over other potential approaches such as the piezoelectric method because of its inherent temperature stability advantage. A reference capacitor and temperature sensor are embedded in the system to compensate for temperature effects. The pressure-sensitive membranes are aluminum 6061, stainless steel (SUS) 403, and metal-coated polyimide plates. The thicknesses of these membranes range from 250 to 500 m. The rigid substrate is made with a 1- to 2-mm-thick wafer of one of the following materials depending on the application requirements glass, silicon, polyimide, PCB substrate. The glass substrate is fabricated by a microelectromechanical systems (MEMS) fabrication approach. Several concentric electrode patterns are printed on the substrate. The initial gap between the two plates, 100 m, is defined by a silicon spacer ring that is anodically bonded to the glass substrate. The fabricated proof-of-concept devices have successfully demonstrated tens to hundreds of picofarads of capacitance change when a simulated sample (100 g to 500 g) is placed on the membrane.

  10. Verification of relationship model between Korean new elderly class's recovery resilience and productive aging.

    PubMed

    Cho, Gun-Sang; Kim, Dae-Sung; Yi, Eun-Surk

    2015-12-01

    The purpose of this study is to verification of relationship model between Korean new elderly class's recovery resilience and productive aging. As of 2013, this study sampled preliminary elderly people in Gyeonggi-do and other provinces nationwide. Data from a total of effective 484 subjects was analyzed. The collected data was processed using the IBM SPSS 20.0 and AMOS 20.0, and underwent descriptive statistical analysis, confirmatory factor analysis, and structure model verification. The path coefficient associated with model fitness was examined. The standardization path coefficient between recovery resilience and productive aging is β=0.975 (t=14.790), revealing a statistically significant positive effect. Thus, it was found that the proposed basic model on the direct path of recovery resilience and productive aging was fit for the model.

  11. Verification of relationship model between Korean new elderly class’s recovery resilience and productive aging

    PubMed Central

    Cho, Gun-Sang; Kim, Dae-Sung; Yi, Eun-Surk

    2015-01-01

    The purpose of this study is to verification of relationship model between Korean new elderly class’s recovery resilience and productive aging. As of 2013, this study sampled preliminary elderly people in Gyeonggi-do and other provinces nationwide. Data from a total of effective 484 subjects was analyzed. The collected data was processed using the IBM SPSS 20.0 and AMOS 20.0, and underwent descriptive statistical analysis, confirmatory factor analysis, and structure model verification. The path coefficient associated with model fitness was examined. The standardization path coefficient between recovery resilience and productive aging is β=0.975 (t=14.790), revealing a statistically significant positive effect. Thus, it was found that the proposed basic model on the direct path of recovery resilience and productive aging was fit for the model. PMID:26730383

  12. Development of a new lattice physics code robin for PWR application

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, S.; Chen, G.

    2013-07-01

    This paper presents a description of methodologies and preliminary verification results of a new lattice physics code ROBIN, being developed for PWR application at Shanghai NuStar Nuclear Power Technology Co., Ltd. The methods used in ROBIN to fulfill various tasks of lattice physics analysis are an integration of historical methods and new methods that came into being very recently. Not only these methods like equivalence theory for resonance treatment and method of characteristics for neutron transport calculation are adopted, as they are applied in many of today's production-level LWR lattice codes, but also very useful new methods like the enhancedmore » neutron current method for Dancoff correction in large and complicated geometry and the log linear rate constant power depletion method for Gd-bearing fuel are implemented in the code. A small sample of verification results are provided to illustrate the type of accuracy achievable using ROBIN. It is demonstrated that ROBIN is capable of satisfying most of the needs for PWR lattice analysis and has the potential to become a production quality code in the future. (authors)« less

  13. Verification of a Viscous Computational Aeroacoustics Code using External Verification Analysis

    NASA Technical Reports Server (NTRS)

    Ingraham, Daniel; Hixon, Ray

    2015-01-01

    The External Verification Analysis approach to code verification is extended to solve the three-dimensional Navier-Stokes equations with constant properties, and is used to verify a high-order computational aeroacoustics (CAA) code. After a brief review of the relevant literature, the details of the EVA approach are presented and compared to the similar Method of Manufactured Solutions (MMS). Pseudocode representations of EVA's algorithms are included, along with the recurrence relations needed to construct the EVA solution. The code verification results show that EVA was able to convincingly verify a high-order, viscous CAA code without the addition of MMS-style source terms, or any other modifications to the code.

  14. Verification of a Viscous Computational Aeroacoustics Code Using External Verification Analysis

    NASA Technical Reports Server (NTRS)

    Ingraham, Daniel; Hixon, Ray

    2015-01-01

    The External Verification Analysis approach to code verification is extended to solve the three-dimensional Navier-Stokes equations with constant properties, and is used to verify a high-order computational aeroacoustics (CAA) code. After a brief review of the relevant literature, the details of the EVA approach are presented and compared to the similar Method of Manufactured Solutions (MMS). Pseudocode representations of EVA's algorithms are included, along with the recurrence relations needed to construct the EVA solution. The code verification results show that EVA was able to convincingly verify a high-order, viscous CAA code without the addition of MMS-style source terms, or any other modifications to the code.

  15. Thermal Pollution Mathematical Model. Volume 4: Verification of Three-Dimensional Rigid-Lid Model at Lake Keowee. [envrionment impact of thermal discharges from power plants

    NASA Technical Reports Server (NTRS)

    Lee, S. S.; Sengupta, S.; Nwadike, E. V.; Sinha, S. K.

    1980-01-01

    The rigid lid model was developed to predict three dimensional temperature and velocity distributions in lakes. This model was verified at various sites (Lake Belews, Biscayne Bay, etc.) and th verification at Lake Keowee was the last of these series of verification runs. The verification at Lake Keowee included the following: (1) selecting the domain of interest, grid systems, and comparing the preliminary results with archival data; (2) obtaining actual ground truth and infrared scanner data both for summer and winter; and (3) using the model to predict the measured data for the above periods and comparing the predicted results with the actual data. The model results compared well with measured data. Thus, the model can be used as an effective predictive tool for future sites.

  16. An Efficient Location Verification Scheme for Static Wireless Sensor Networks.

    PubMed

    Kim, In-Hwan; Kim, Bo-Sung; Song, JooSeok

    2017-01-24

    In wireless sensor networks (WSNs), the accuracy of location information is vital to support many interesting applications. Unfortunately, sensors have difficulty in estimating their location when malicious sensors attack the location estimation process. Even though secure localization schemes have been proposed to protect location estimation process from attacks, they are not enough to eliminate the wrong location estimations in some situations. The location verification can be the solution to the situations or be the second-line defense. The problem of most of the location verifications is the explicit involvement of many sensors in the verification process and requirements, such as special hardware, a dedicated verifier and the trusted third party, which causes more communication and computation overhead. In this paper, we propose an efficient location verification scheme for static WSN called mutually-shared region-based location verification (MSRLV), which reduces those overheads by utilizing the implicit involvement of sensors and eliminating several requirements. In order to achieve this, we use the mutually-shared region between location claimant and verifier for the location verification. The analysis shows that MSRLV reduces communication overhead by 77% and computation overhead by 92% on average, when compared with the other location verification schemes, in a single sensor verification. In addition, simulation results for the verification of the whole network show that MSRLV can detect the malicious sensors by over 90% when sensors in the network have five or more neighbors.

  17. An Efficient Location Verification Scheme for Static Wireless Sensor Networks

    PubMed Central

    Kim, In-hwan; Kim, Bo-sung; Song, JooSeok

    2017-01-01

    In wireless sensor networks (WSNs), the accuracy of location information is vital to support many interesting applications. Unfortunately, sensors have difficulty in estimating their location when malicious sensors attack the location estimation process. Even though secure localization schemes have been proposed to protect location estimation process from attacks, they are not enough to eliminate the wrong location estimations in some situations. The location verification can be the solution to the situations or be the second-line defense. The problem of most of the location verifications is the explicit involvement of many sensors in the verification process and requirements, such as special hardware, a dedicated verifier and the trusted third party, which causes more communication and computation overhead. In this paper, we propose an efficient location verification scheme for static WSN called mutually-shared region-based location verification (MSRLV), which reduces those overheads by utilizing the implicit involvement of sensors and eliminating several requirements. In order to achieve this, we use the mutually-shared region between location claimant and verifier for the location verification. The analysis shows that MSRLV reduces communication overhead by 77% and computation overhead by 92% on average, when compared with the other location verification schemes, in a single sensor verification. In addition, simulation results for the verification of the whole network show that MSRLV can detect the malicious sensors by over 90% when sensors in the network have five or more neighbors. PMID:28125007

  18. Assessment of the Content of Fluorescent Tracer in Granular Feed Mixture.

    PubMed

    Matuszek, Dominika B; Wojtkiewicz, Krystian

    2018-05-03

    Background: This paper describes the use of fluorescence induced by UV radiation to evaluate the share of tracer in feed mixture. Methods: For the purpose of this study, three substances were used. They are as follows: Tinopal, Rhodamine B, and Uranine. Tracer in the form of maize or kardi was added to chicken feed before the mixing process. Grains used in the process were grinded in the mill sieve with a mesh size of 4 and 6 mm. The drawn samples of the mixture were illuminated with UV radiation to make grain tracer light, and then the photo was taken with a digital camera. The acquired images were analyzed with the use of a computer program running on the RGB color model, which was the way to obtain essential information about the percentage share of tracer. Results: It was observed that, in the case of kardi grains, the proposed method gives results significantly deviating from the verification method. Conclusions: Only the tests with the use of maize having an average particle diameter of 2.4 mm and tinted with the solution of Rhodamine B led to acceptable results (consensual with the predetermined verification level).

  19. Ultrasonic Method for Deployment Mechanism Bolt Element Preload Verification

    NASA Technical Reports Server (NTRS)

    Johnson, Eric C.; Kim, Yong M.; Morris, Fred A.; Mitchell, Joel; Pan, Robert B.

    2014-01-01

    Deployment mechanisms play a pivotal role in mission success. These mechanisms often incorporate bolt elements for which a preload within a specified range is essential for proper operation. A common practice is to torque these bolt elements to a specified value during installation. The resulting preload, however, can vary significantly with applied torque for a number of reasons. The goal of this effort was to investigate ultrasonic methods as an alternative for bolt preload verification in such deployment mechanisms. A family of non-explosive release mechanisms widely used by satellite manufacturers was chosen for the work. A willing contractor permitted measurements on a sampling of bolt elements for these release mechanisms that were installed by a technician following a standard practice. A variation of approximately 50% (+/- 25%) in the resultant preloads was observed. An alternative ultrasonic method to set the preloads was then developed and calibration data was accumulated. The method was demonstrated on bolt elements installed in a fixture instrumented with a calibrated load cell and designed to mimic production practice. The ultrasonic method yielded results within +/- 3% of the load cell reading. The contractor has since adopted the alternative method for its future production. Introduction

  20. 40 CFR 86.1845-01 - Manufacturer in-use verification testing requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of test vehicles in the sample comply with the sample size requirements of this section. Any post... vehicles, light-duty trucks, and complete heavy-duty vehicles shall test, or cause to have tested a...) Low mileage testing. [Reserved] (c) High-mileage testing—(1) Test groups. Testing must be conducted...

  1. 40 CFR 86.1845-01 - Manufacturer in-use verification testing requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of test vehicles in the sample comply with the sample size requirements of this section. Any post... vehicles, light-duty trucks, and complete heavy-duty vehicles shall test, or cause to have tested a...) Low mileage testing. [Reserved] (c) High-mileage testing—(1) Test groups. Testing must be conducted...

  2. 40 CFR 86.1845-01 - Manufacturer in-use verification testing requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of test vehicles in the sample comply with the sample size requirements of this section. Any post... vehicles, light-duty trucks, and complete heavy-duty vehicles shall test, or cause to have tested a...) Low mileage testing. [Reserved] (c) High-mileage testing—(1) Test groups. Testing must be conducted...

  3. 40 CFR 86.1845-01 - Manufacturer in-use verification testing requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... of test vehicles in the sample comply with the sample size requirements of this section. Any post... vehicles, light-duty trucks, and complete heavy-duty vehicles shall test, or cause to have tested a...) Low mileage testing. [Reserved] (c) High-mileage testing—(1) Test groups. Testing must be conducted...

  4. Demonstration Report for Visual Sample Plan (VSP) Verification Sampling Methods at the Navy/DRI Site

    DTIC Science & Technology

    2011-08-01

    population of 537,197 with an overall population density of 608 people per square mile (people/ mi2 ). However, the population density in the vicinity...Preliminary Assessment Findings  approximately 12 people/ mi2 . Population density is expected to greatly increase following development of the site

  5. Weak lensing magnification in the Dark Energy Survey Science Verification Data

    DOE PAGES

    Garcia-Fernandez, M.; et al.

    2018-02-02

    In this paper the effect of weak lensing magnification on galaxy number counts is studied by cross-correlating the positions of two galaxy samples, separated by redshift, using data from the Dark Energy Survey Science Verification dataset. The analysis is carried out for two photometrically-selected galaxy samples, with mean photometric redshifts in themore » $0.2 < z < 0.4$ and $0.7 < z < 1.0$ ranges, in the riz bands. A signal is detected with a $$3.5\\sigma$$ significance level in each of the bands tested, and is compatible with the magnification predicted by the $$\\Lambda$$CDM model. After an extensive analysis, it cannot be attributed to any known systematic effect. The detection of the magnification signal is robust to estimated uncertainties in the outlier rate of the pho- tometric redshifts, but this will be an important issue for use of photometric redshifts in magnification mesurements from larger samples. In addition to the detection of the magnification signal, a method to select the sample with the maximum signal-to-noise is proposed and validated with data.« less

  6. Weak lensing magnification in the Dark Energy Survey Science Verification Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Garcia-Fernandez, M.; et al.

    In this paper the effect of weak lensing magnification on galaxy number counts is studied by cross-correlating the positions of two galaxy samples, separated by redshift, using data from the Dark Energy Survey Science Verification dataset. The analysis is carried out for two photometrically-selected galaxy samples, with mean photometric redshifts in themore » $0.2 < z < 0.4$ and $0.7 < z < 1.0$ ranges, in the riz bands. A signal is detected with a $$3.5\\sigma$$ significance level in each of the bands tested, and is compatible with the magnification predicted by the $$\\Lambda$$CDM model. After an extensive analysis, it cannot be attributed to any known systematic effect. The detection of the magnification signal is robust to estimated uncertainties in the outlier rate of the pho- tometric redshifts, but this will be an important issue for use of photometric redshifts in magnification mesurements from larger samples. In addition to the detection of the magnification signal, a method to select the sample with the maximum signal-to-noise is proposed and validated with data.« less

  7. Weak lensing magnification in the Dark Energy Survey Science Verification Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Garcia-Fernandez, M.; et al.

    2016-11-30

    In this paper the effect of weak lensing magnification on galaxy number counts is studied by cross-correlating the positions of two galaxy samples, separated by redshift, using data from the Dark Energy Survey Science Verification dataset. The analysis is carried out for two photometrically-selected galaxy samples, with mean photometric redshifts in themore » $0.2 < z < 0.4$ and $0.7 < z < 1.0$ ranges, in the riz bands. A signal is detected with a $$3.5\\sigma$$ significance level in each of the bands tested, and is compatible with the magnification predicted by the $$\\Lambda$$CDM model. After an extensive analysis, it cannot be attributed to any known systematic effect. The detection of the magnification signal is robust to estimated uncertainties in the outlier rate of the pho- tometric redshifts, but this will be an important issue for use of photometric redshifts in magnification mesurements from larger samples. In addition to the detection of the magnification signal, a method to select the sample with the maximum signal-to-noise is proposed and validated with data.« less

  8. A Probabilistic Mass Estimation Algorithm for a Novel 7- Channel Capacitive Sample Verification Sensor

    NASA Technical Reports Server (NTRS)

    Wolf, Michael

    2012-01-01

    A document describes an algorithm created to estimate the mass placed on a sample verification sensor (SVS) designed for lunar or planetary robotic sample return missions. A novel SVS measures the capacitance between a rigid bottom plate and an elastic top membrane in seven locations. As additional sample material (soil and/or small rocks) is placed on the top membrane, the deformation of the membrane increases the capacitance. The mass estimation algorithm addresses both the calibration of each SVS channel, and also addresses how to combine the capacitances read from each of the seven channels into a single mass estimate. The probabilistic approach combines the channels according to the variance observed during the training phase, and provides not only the mass estimate, but also a value for the certainty of the estimate. SVS capacitance data is collected for known masses under a wide variety of possible loading scenarios, though in all cases, the distribution of sample within the canister is expected to be approximately uniform. A capacitance-vs-mass curve is fitted to this data, and is subsequently used to determine the mass estimate for the single channel s capacitance reading during the measurement phase. This results in seven different mass estimates, one for each SVS channel. Moreover, the variance of the calibration data is used to place a Gaussian probability distribution function (pdf) around this mass estimate. To blend these seven estimates, the seven pdfs are combined into a single Gaussian distribution function, providing the final mean and variance of the estimate. This blending technique essentially takes the final estimate as an average of the estimates of the seven channels, weighted by the inverse of the channel s variance.

  9. Verification of chemistry reference ranges using a simple method in sub-Saharan Africa

    PubMed Central

    Taylor, Douglas; Mandala, Justin; Nanda, Kavita; Van Campenhout, Christel; Agingu, Walter; Madurai, Lorna; Barsch, Eva-Maria; Deese, Jennifer; Van Damme, Lut; Crucitti, Tania

    2016-01-01

    Background Chemistry safety assessments are interpreted by using chemistry reference ranges (CRRs). Verification of CRRs is time consuming and often requires a statistical background. Objectives We report on an easy and cost-saving method to verify CRRs. Methods Using a former method introduced by Sigma Diagnostics, three study sites in sub-Saharan Africa, Bondo, Kenya, and Pretoria and Bloemfontein, South Africa, verified the CRRs for hepatic and renal biochemistry assays performed during a clinical trial of HIV antiretroviral pre-exposure prophylaxis. The aspartate aminotransferase/alanine aminotransferase, creatinine and phosphorus results from 10 clinically-healthy participants at the screening visit were used. In the event the CRRs did not pass the verification, new CRRs had to be calculated based on 40 clinically-healthy participants. Results Within a few weeks, the study sites accomplished verification of the CRRs without additional costs. The aspartate aminotransferase reference ranges for the Bondo, Kenya site and the alanine aminotransferase reference ranges for the Pretoria, South Africa site required adjustment. The phosphorus CRR passed verification and the creatinine CRR required adjustment at every site. The newly-established CRR intervals were narrower than the CRRs used previously at these study sites due to decreases in the upper limits of the reference ranges. As a result, more toxicities were detected. Conclusion To ensure the safety of clinical trial participants, verification of CRRs should be standard practice in clinical trials conducted in settings where the CRR has not been validated for the local population. This verification method is simple, inexpensive, and can be performed by any medical laboratory. PMID:28879112

  10. Being known, intimate, and valued: global self-verification and dyadic adjustment in couples and roommates.

    PubMed

    Katz, Jennifer; Joiner, Thomas E

    2002-02-01

    We contend that close relationships provide adults with optimal opportunities for personal growth when relationship partners provide accurate, honest feedback. Accordingly, it was predicted that young adults would experience the relationship quality with relationship partners who evaluated them in a manner consistent their own self-evaluations. Three empirical tests of this self-verification hypothesis as applied to close dyads were conducted. In Study 1, young adults in dating relationships were most intimate with and somewhat more committed to partners when they perceived that partners evaluated them as they evaluated themselves. Self-verification effects were pronounced for those involved in more serious dating relationships. In Study 2, men reported the greatest esteem for same-sex roommates who evaluated them in a self-verifying manner. Results from Study 2 were replicated and extended to both male and female roommate dyads in Study 3. Further, self-verification effects were most pronounced for young adults with high emotional empathy. Results suggest that self-verification theory is useful for understanding dyadic adjustment across a variety of relational contexts in young adulthood. Implications of self-verification processes for adult personal development are outlined within an identity negotiation framework.

  11. Verification and quality control of routine hematology analyzers.

    PubMed

    Vis, J Y; Huisman, A

    2016-05-01

    Verification of hematology analyzers (automated blood cell counters) is mandatory before new hematology analyzers may be used in routine clinical care. The verification process consists of several items which comprise among others: precision, accuracy, comparability, carryover, background and linearity throughout the expected range of results. Yet, which standard should be met or which verification limit be used is at the discretion of the laboratory specialist. This paper offers practical guidance on verification and quality control of automated hematology analyzers and provides an expert opinion on the performance standard that should be met by the contemporary generation of hematology analyzers. Therefore (i) the state-of-the-art performance of hematology analyzers for complete blood count parameters is summarized, (ii) considerations, challenges, and pitfalls concerning the development of a verification plan are discussed, (iii) guidance is given regarding the establishment of reference intervals, and (iv) different methods on quality control of hematology analyzers are reviewed. © 2016 John Wiley & Sons Ltd.

  12. Study on verifying the angle measurement performance of the rotary-laser system

    NASA Astrophysics Data System (ADS)

    Zhao, Jin; Ren, Yongjie; Lin, Jiarui; Yin, Shibin; Zhu, Jigui

    2018-04-01

    An angle verification method to verify the angle measurement performance of the rotary-laser system was developed. Angle measurement performance has a great impact on measuring accuracy. Although there is some previous research on the verification of angle measuring uncertainty for the rotary-laser system, there are still some limitations. High-precision reference angles are used in the study of the method, and an integrated verification platform is set up to evaluate the performance of the system. This paper also probes the error that has biggest influence on the verification system. Some errors of the verification system are avoided via the experimental method, and some are compensated through the computational formula and curve fitting. Experimental results show that the angle measurement performance meets the requirement for coordinate measurement. The verification platform can evaluate the uncertainty of angle measurement for the rotary-laser system efficiently.

  13. A Hybrid On-line Verification Method of Relay Setting

    NASA Astrophysics Data System (ADS)

    Gao, Wangyuan; Chen, Qing; Si, Ji; Huang, Xin

    2017-05-01

    Along with the rapid development of the power industry, grid structure gets more sophisticated. The validity and rationality of protective relaying are vital to the security of power systems. To increase the security of power systems, it is essential to verify the setting values of relays online. Traditional verification methods mainly include the comparison of protection range and the comparison of calculated setting value. To realize on-line verification, the verifying speed is the key. The verifying result of comparing protection range is accurate, but the computation burden is heavy, and the verifying speed is slow. Comparing calculated setting value is much faster, but the verifying result is conservative and inaccurate. Taking the overcurrent protection as example, this paper analyses the advantages and disadvantages of the two traditional methods above, and proposes a hybrid method of on-line verification which synthesizes the advantages of the two traditional methods. This hybrid method can meet the requirements of accurate on-line verification.

  14. Code Verification Capabilities and Assessments in Support of ASC V&V Level 2 Milestone #6035

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Doebling, Scott William; Budzien, Joanne Louise; Ferguson, Jim Michael

    This document provides a summary of the code verification activities supporting the FY17 Level 2 V&V milestone entitled “Deliver a Capability for V&V Assessments of Code Implementations of Physics Models and Numerical Algorithms in Support of Future Predictive Capability Framework Pegposts.” The physics validation activities supporting this milestone are documented separately. The objectives of this portion of the milestone are: 1) Develop software tools to support code verification analysis; 2) Document standard definitions of code verification test problems; and 3) Perform code verification assessments (focusing on error behavior of algorithms). This report and a set of additional standalone documents servemore » as the compilation of results demonstrating accomplishment of these objectives.« less

  15. VAVUQ, Python and Matlab freeware for Verification and Validation, Uncertainty Quantification

    NASA Astrophysics Data System (ADS)

    Courtney, J. E.; Zamani, K.; Bombardelli, F. A.; Fleenor, W. E.

    2015-12-01

    A package of scripts is presented for automated Verification and Validation (V&V) and Uncertainty Quantification (UQ) for engineering codes that approximate Partial Differential Equations (PDFs). The code post-processes model results to produce V&V and UQ information. This information can be used to assess model performance. Automated information on code performance can allow for a systematic methodology to assess the quality of model approximations. The software implements common and accepted code verification schemes. The software uses the Method of Manufactured Solutions (MMS), the Method of Exact Solution (MES), Cross-Code Verification, and Richardson Extrapolation (RE) for solution (calculation) verification. It also includes common statistical measures that can be used for model skill assessment. Complete RE can be conducted for complex geometries by implementing high-order non-oscillating numerical interpolation schemes within the software. Model approximation uncertainty is quantified by calculating lower and upper bounds of numerical error from the RE results. The software is also able to calculate the Grid Convergence Index (GCI), and to handle adaptive meshes and models that implement mixed order schemes. Four examples are provided to demonstrate the use of the software for code and solution verification, model validation and uncertainty quantification. The software is used for code verification of a mixed-order compact difference heat transport solver; the solution verification of a 2D shallow-water-wave solver for tidal flow modeling in estuaries; the model validation of a two-phase flow computation in a hydraulic jump compared to experimental data; and numerical uncertainty quantification for 3D CFD modeling of the flow patterns in a Gust erosion chamber.

  16. Litmus tests for verification of feeding tube location in infants: evaluation of their clinical use.

    PubMed

    Nyqvist, Kerstin Hedberg; Sorell, Annette; Ewald, Uwe

    2005-04-01

    To examine the clinical use of litmus paper tests for the assessment of aspirates in infants. In connection with establishing a programme for home care of infants with requirement of tube feeding with parents as the infants' carers, the need for a research-based method for verification of feeding tube position was identified by nurses as a complement to other methods. In adult care the litmus paper test is commonly used when visual inspection is not sufficient for assessment of aspirates obtained from feeding tubes. Observational study. Nurses performed litmus tests for verification of feeding tube location in a convenience sample of 60 infants born at a gestational age (GA) of 24-42 weeks. Presence/absence and volumes of aspirates were recorded as well as positive/negative litmus test reactions. Analyses on the association between test results and the infants' GA and postmenstrual and postnatal age at the time of the tests were conducted. Data were obtained from 2970 tube feeds. Aspirates were present on 1840 occasions (62%). A higher proportion of infants with absence of aspirates were born at a GA below 32 weeks. A positive reaction occurred in 97% of the tests in volumes between 0.01 and 22 ml. Birth at a GA below 32 weeks and respiratory problems were associated with negative tests. The high ratio of positive litmus reactions at all maturational levels supports the bedside use of analysis of pH in gastric aspirates for verification of feeding tube location. Application of pH indicator paper is recommended as a complementary method for assessment of aspirates from feeding tubes.

  17. Verification of the NWP models operated at ICM, Poland

    NASA Astrophysics Data System (ADS)

    Melonek, Malgorzata

    2010-05-01

    Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw (ICM) started its activity in the field of NWP in May 1997. Since this time the numerical weather forecasts covering Central Europe have been routinely published on our publicly available website. First NWP model used in ICM was hydrostatic Unified Model developed by the UK Meteorological Office. It was a mesoscale version with horizontal resolution of 17 km and 31 levels in vertical. At present two NWP non-hydrostatic models are running in quasi-operational regime. The main new UM model with 4 km horizontal resolution, 38 levels in vertical and forecats range of 48 hours is running four times a day. Second, the COAMPS model (Coupled Ocean/Atmosphere Mesoscale Prediction System) developed by the US Naval Research Laboratory, configured with the three nested grids (with coresponding resolutions of 39km, 13km and 4.3km, 30 vertical levels) are running twice a day (for 00 and 12 UTC). The second grid covers Central Europe and has forecast range of 84 hours. Results of the both NWP models, ie. COAMPS computed on 13km mesh resolution and UM, are verified against observations from the Polish synoptic stations. Verification uses surface observations and nearest grid point forcasts. Following meteorological elements are verified: air temperature at 2m, mean sea level pressure, wind speed and wind direction at 10 m and 12 hours accumulated precipitation. There are presented different statistical indices. For continous variables Mean Error(ME), Mean Absolute Error (MAE) and Root Mean Squared Error (RMSE) in 6 hours intervals are computed. In case of precipitation the contingency tables for different thresholds are computed and some of the verification scores such as FBI, ETS, POD, FAR are graphically presented. The verification sample covers nearly one year.

  18. Applying Monte Carlo Simulation to Launch Vehicle Design and Requirements Verification

    NASA Technical Reports Server (NTRS)

    Hanson, John M.; Beard, Bernard B.

    2010-01-01

    This paper is focused on applying Monte Carlo simulation to probabilistic launch vehicle design and requirements verification. The approaches developed in this paper can be applied to other complex design efforts as well. Typically the verification must show that requirement "x" is met for at least "y" % of cases, with, say, 10% consumer risk or 90% confidence. Two particular aspects of making these runs for requirements verification will be explored in this paper. First, there are several types of uncertainties that should be handled in different ways, depending on when they become known (or not). The paper describes how to handle different types of uncertainties and how to develop vehicle models that can be used to examine their characteristics. This includes items that are not known exactly during the design phase but that will be known for each assembled vehicle (can be used to determine the payload capability and overall behavior of that vehicle), other items that become known before or on flight day (can be used for flight day trajectory design and go/no go decision), and items that remain unknown on flight day. Second, this paper explains a method (order statistics) for determining whether certain probabilistic requirements are met or not and enables the user to determine how many Monte Carlo samples are required. Order statistics is not new, but may not be known in general to the GN&C community. The methods also apply to determining the design values of parameters of interest in driving the vehicle design. The paper briefly discusses when it is desirable to fit a distribution to the experimental Monte Carlo results rather than using order statistics.

  19. Sample processing approach for detection of ricin in surface samples.

    PubMed

    Kane, Staci; Shah, Sanjiv; Erler, Anne Marie; Alfaro, Teneile

    2017-12-01

    With several ricin contamination incidents reported over the past decade, rapid and accurate methods are needed for environmental sample analysis, especially after decontamination. A sample processing method was developed for common surface sampling devices to improve the limit of detection and avoid false negative/positive results for ricin analysis. Potential assay interferents from the sample matrix (bleach residue, sample material, wetting buffer), including reference dust, were tested using a Time-Resolved Fluorescence (TRF) immunoassay. Test results suggested that the sample matrix did not cause the elevated background fluorescence sometimes observed when analyzing post-bleach decontamination samples from ricin incidents. Furthermore, sample particulates (80mg/mL Arizona Test Dust) did not enhance background fluorescence or interfere with ricin detection by TRF. These results suggested that high background fluorescence in this immunoassay could be due to labeled antibody quality and/or quantity issues. Centrifugal ultrafiltration devices were evaluated for ricin concentration as a part of sample processing. Up to 30-fold concentration of ricin was observed by the devices, which serve to remove soluble interferents and could function as the front-end sample processing step to other ricin analytical methods. The procedure has the potential to be used with a broader range of environmental sample types and with other potential interferences and to be followed by other ricin analytical methods, although additional verification studies would be required. Published by Elsevier B.V.

  20. Remaining Sites Verification Package for the 100-F-54 Animal Farm Pastures, Waste Site Reclassification Form 2008-015

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    J. M. Capron

    2008-04-17

    The 100-F-54 waste site, part of the 100-FR-2 Operable Unit, is the soil associated with the former pastures for holding domestic farm animals used in experimental toxicology studies. Evaluation of historical information resulted in identification of the experimental animal farm pastures as having potential residual soil contamination due to excrement from experimental animals. The 100-F-54 animal farm pastures confirmatory sampling results support a reclassification of this site to No Action. The current site conditions achieve the remedial action objectives and the corresponding remedial action goals established in the Remaining Sites ROD. The results of confirmatory sampling show that residual contaminantmore » concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also demonstrate that residual contaminant concentrations are protective of groundwater and the Columbia River.« less

  1. Can self-verification strivings fully transcend the self-other barrier? Seeking verification of ingroup identities.

    PubMed

    Gómez, Angel; Seyle, D Conor; Huici, Carmen; Swann, William B

    2009-12-01

    Recent research has demonstrated self-verification strivings in groups, such that people strive to verify collective identities, which are personal self-views (e.g., "sensitive") associated with group membership (e.g., "women"). Such demonstrations stop short of showing that the desire for self-verification can fully transcend the self-other barrier, as in people working to verify ingroup identities (e.g., "Americans are loud") even when such identities are not self-descriptive ("I am quiet and unassuming"). Five studies focus on such ingroup verification strivings. Results indicate that people prefer to interact with individuals who verify their ingroup identities over those who enhance these identities (Experiments 1-5). Strivings for ingroup identity verification were independent of the extent to which the identities were self-descriptive but were stronger among participants who were highly invested in their ingroup identities, as reflected in high certainty of these identities (Experiments 1-4) and high identification with the group (Experiments 1-5). In addition, whereas past demonstrations of self-verification strivings have been limited to efforts to verify the content of identities (Experiments 1 to 3), the findings also show that they strive to verify the valence of their identities (i.e., the extent to which the identities are valued; Experiments 4 and 5). Self-verification strivings, rather than self-enhancement strivings, appeared to motivate participants' strivings for ingroup identity verification. Links to collective self-verification strivings and social identity theory are discussed.

  2. Verification of the new detection method for irradiated spices based on microbial survival by collaborative blind trial

    NASA Astrophysics Data System (ADS)

    Miyahara, M.; Furuta, M.; Takekawa, T.; Oda, S.; Koshikawa, T.; Akiba, T.; Mori, T.; Mimura, T.; Sawada, C.; Yamaguchi, T.; Nishioka, S.; Tada, M.

    2009-07-01

    An irradiation detection method using the difference of the radiation sensitivity of the heat-treated microorganisms was developed as one of the microbiological detection methods of the irradiated foods. This detection method is based on the difference of the viable cell count before and after heat treatment (70 °C and 10 min). The verification by collaborative blind trial of this method was done by nine inspecting agencies in Japan. The samples used for this trial were five kinds of spices consisting of non-irradiated, 5 kGy irradiated, and 7 kGy irradiated black pepper, allspice, oregano, sage, and paprika, respectively. As a result of this collaboration, a high percentage (80%) of the correct answers was obtained for irradiated black pepper and allspice. However, the method was less successful for irradiated oregano, sage, and paprika. It might be possible to use this detection method for preliminary screening of the irradiated foods but further work is necessary to confirm these findings.

  3. Experiences using IAEA Code of practice for radiation sterilization of tissue allografts: Validation and routine control

    NASA Astrophysics Data System (ADS)

    Hilmy, N.; Febrida, A.; Basril, A.

    2007-11-01

    Problems of tissue allografts in using International Standard (ISO) 11137 for validation of radiation sterilization dose (RSD) are limited and low numbers of uniform samples per production batch, those are products obtained from one donor. Allograft is a graft transplanted between two different individuals of the same species. The minimum number of uniform samples needed for verification dose (VD) experiment at the selected sterility assurance level (SAL) per production batch according to the IAEA Code is 20, i.e., 10 for bio-burden determination and the remaining 10 for sterilization test. Three methods of the IAEA Code have been used for validation of RSD, i.e., method A1 that is a modification of method 1 of ISO 11137:1995, method B (ISO 13409:1996), and method C (AAMI TIR 27:2001). This paper describes VD experiments using uniform products obtained from one cadaver donor, i.e., cancellous bones, demineralized bone powders and amnion grafts from one life donor. Results of the verification dose experiments show that RSD is 15.4 kGy for cancellous and demineralized bone grafts and 19.2 kGy for amnion grafts according to method A1 and 25 kGy according to methods B and C.

  4. Palmprint and face score level fusion: hardware implementation of a contactless small sample biometric system

    NASA Astrophysics Data System (ADS)

    Poinsot, Audrey; Yang, Fan; Brost, Vincent

    2011-02-01

    Including multiple sources of information in personal identity recognition and verification gives the opportunity to greatly improve performance. We propose a contactless biometric system that combines two modalities: palmprint and face. Hardware implementations are proposed on the Texas Instrument Digital Signal Processor and Xilinx Field-Programmable Gate Array (FPGA) platforms. The algorithmic chain consists of a preprocessing (which includes palm extraction from hand images), Gabor feature extraction, comparison by Hamming distance, and score fusion. Fusion possibilities are discussed and tested first using a bimodal database of 130 subjects that we designed (uB database), and then two common public biometric databases (AR for face and PolyU for palmprint). High performance has been obtained for recognition and verification purpose: a recognition rate of 97.49% with AR-PolyU database and an equal error rate of 1.10% on the uB database using only two training samples per subject have been obtained. Hardware results demonstrate that preprocessing can easily be performed during the acquisition phase, and multimodal biometric recognition can be treated almost instantly (0.4 ms on FPGA). We show the feasibility of a robust and efficient multimodal hardware biometric system that offers several advantages, such as user-friendliness and flexibility.

  5. Screening of nitrogen mustards and their degradation products in water and decontamination solution by liquid chromatography-mass spectrometry.

    PubMed

    Chua, Hoe-Chee; Lee, Hoi-Sim; Sng, Mui-Tiang

    2006-01-13

    Analysing nitrogen mustards and their degradation products in decontamination emulsions posed a significant challenge due to the different phases present in such matrices. Extensive sample preparation may be required to isolate target analytes. Furthermore, numerous reaction products are formed in the decontamination emulsion. A fast and effective qualitative screening procedure was developed for these compounds, using liquid chromatography-mass spectrometry (LC-MS). This eliminated the need for additional sample handling and derivatisation that are required for gas chromatographic-mass spectrometric (GC-MS) analysis. A liquid chromatograph with mixed mode column and isocratic elution gave good chromatography. The feasibility of applying this technique for detecting these compounds in spiked water and decontamination emulsion was demonstrated. Detailed characterisation of the degradation products in these two matrices was carried out. The results demonstrated that N-methyldiethanolamine (MDEA), N-ethyldiethanolamine (EDEA) and triethanolamine (TEA) are not the major degradation products of their respective nitrogen mustards. Degradation profiles of nitrogen mustards in water were also established. In verification analysis, it is important not only to develop methods for the identification of the actual chemical agents; the methods must also encompass degradation products of the chemical agents as well so as to exclude false negatives. This study demonstrated the increasingly pivotal role that LC-MS play in verification analysis.

  6. General Dynamic (GD) Launch Waveform On-Orbit Performance Report

    NASA Technical Reports Server (NTRS)

    Briones, Janette C.; Shalkhauser, Mary Jo

    2014-01-01

    The purpose of this report is to present the results from the GD SDR on-orbit performance testing using the launch waveform over TDRSS. The tests include the evaluation of well-tested waveform modes, the operation of RF links that are expected to have high margins, the verification of forward return link operation (including full duplex), the verification of non-coherent operational models, and the verification of radio at-launch operational frequencies. This report also outlines the launch waveform tests conducted and comparisons to the results obtained from ground testing.

  7. Hosted Services for Advanced V and V Technologies: An Approach to Achieving Adoption without the Woes of Usage

    NASA Technical Reports Server (NTRS)

    Koga, Dennis (Technical Monitor); Penix, John; Markosian, Lawrence Z.; OMalley, Owen; Brew, William A.

    2003-01-01

    Attempts to achieve widespread use of software verification tools have been notably unsuccessful. Even 'straightforward', classic, and potentially effective verification tools such as lint-like tools face limits on their acceptance. These limits are imposed by the expertise required applying the tools and interpreting the results, the high false positive rate of many verification tools, and the need to integrate the tools into development environments. The barriers are even greater for more complex advanced technologies such as model checking. Web-hosted services for advanced verification technologies may mitigate these problems by centralizing tool expertise. The possible benefits of this approach include eliminating the need for software developer expertise in tool application and results filtering, and improving integration with other development tools.

  8. Remaining Sites Verification Package for the 100-F-44:2, Discovery Pipeline Near 108-F Building, Waste Site Reclassification Form 2007-006

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    J. M. Capron

    2008-05-30

    The 100-F-44:2 waste site is a steel pipeline that was discovered in a junction box during confirmatory sampling of the 100-F-26:4 pipeline from December 2004 through January 2005. The 100-F-44:2 pipeline feeds into the 100-F-26:4 subsite vitrified clay pipe (VCP) process sewer pipeline from the 108-F Biology Laboratory at the junction box. In accordance with this evaluation, the confirmatory sampling results support a reclassification of this site to No Action. The current site conditions achieve the remedial action objectives and the corresponding remedial action goals established in the Remaining Sites ROD. The results of confirmatory sampling show that residual contaminantmore » concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also demonstrate that residual contaminant concentrations are protective of groundwater and the Columbia River.« less

  9. Designing an autoverification system in Zagazig University Hospitals Laboratories: preliminary evaluation on thyroid function profile.

    PubMed

    Sediq, Amany Mohy-Eldin; Abdel-Azeez, Ahmad GabAllahm Hala

    2014-01-01

    The current practice in Zagazig University Hospitals Laboratories (ZUHL) is manual verification of all results for the later release of reports. These processes are time consuming and tedious, with large inter-individual variation that slows the turnaround time (TAT). Autoverification is the process of comparing patient results, generated from interfaced instruments, against laboratory-defined acceptance parameters. This study describes an autoverification engine designed and implemented in ZUHL, Egypt. A descriptive study conducted at ZUHL, from January 2012-December 2013. A rule-based system was used in designing an autoverification engine. The engine was preliminarily evaluated on a thyroid function panel. A total of 563 rules were written and tested on 563 simulated cases and 1673 archived cases. The engine decisions were compared to that of 4 independent expert reviewers. The impact of engine implementation on TAT was evaluated. Agreement was achieved among the 4 reviewers in 55.5% of cases, and with the engine in 51.5% of cases. The autoverification rate for archived cases was 63.8%. Reported lab TAT was reduced by 34.9%, and TAT segment from the completion of analysis to verification was reduced by 61.8%. The developed rule-based autoverification system has a verification rate comparable to that of the commercially available software. However, the in-house development of this system had saved the hospital the cost of commercially available ones. The implementation of the system shortened the TAT and minimized the number of samples that needed staff revision, which enabled laboratory staff to devote more time and effort to handle problematic test results and to improve patient care quality.

  10. Built-in-Test Verification Techniques

    DTIC Science & Technology

    1987-02-01

    report documents the results of the effort for the Rome Air Development Center Contract F30602-84-C-0021, BIT Verification Techniques. The work was...Richard Spillman of Sp.,llman Research Associates. The principal investigators were Mike Partridge and subsequently Jeffrey Albert. The contract was...two your effort to develop techniques for Built-In Test (BIT) verification. The objective of the contract was to develop specifications and technical

  11. Enhanced verification test suite for physics simulation codes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kamm, James R.; Brock, Jerry S.; Brandon, Scott T.

    2008-09-01

    This document discusses problems with which to augment, in quantity and in quality, the existing tri-laboratory suite of verification problems used by Los Alamos National Laboratory (LANL), Lawrence Livermore National Laboratory (LLNL), and Sandia National Laboratories (SNL). The purpose of verification analysis is demonstrate whether the numerical results of the discretization algorithms in physics and engineering simulation codes provide correct solutions of the corresponding continuum equations.

  12. Evaluation of AK-225(R), Vertrel(R) MCA and HFE A 7100 as Alternative Solvents for Precision Cleaning and Verification Technology

    NASA Technical Reports Server (NTRS)

    Melendez, Orlando; Trizzino, Mary; Fedderson, Bryan

    1997-01-01

    The National Aeronautics and Space Administration (NASA), Kennedy Space Center (KSC) Materials Science Division conducted a study to evaluate alternative solvents for CFC-113 in precision cleaning and verification on typical samples that are used in the KSC environment. The effects of AK-225(R), Vertrel(R), MCA, and HFE A 7100 on selected metal and polymer materials were studied over 1, 7 and 30 day test times. This report addresses a study on the compatibility aspects of replacement solvents for materials in aerospace applications.

  13. SU-E-T-435: Development and Commissioning of a Complete System for In-Vivo Dosimetry and Range Verification in Proton Therapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Samuel, D; Testa, M; Park, Y

    Purpose: In-vivo dose and beam range verification in proton therapy could play significant roles in proton treatment validation and improvements. Invivo beam range verification, in particular, could enable new treatment techniques one of which, for example, could be the use of anterior fields for prostate treatment instead of opposed lateral fields as in current practice. We have developed and commissioned an integrated system with hardware, software and workflow protocols, to provide a complete solution, simultaneously for both in-vivo dosimetry and range verification for proton therapy. Methods: The system uses a matrix of diodes, up to 12 in total, but separablemore » into three groups for flexibility in application. A special amplifier was developed to capture extremely small signals from very low proton beam current. The software was developed within iMagX, a general platform for image processing in radiation therapy applications. The range determination exploits the inherent relationship between the internal range modulation clock of the proton therapy system and the radiological depth at the point of measurement. The commissioning of the system, for in-vivo dosimetry and for range verification was separately conducted using anthropomorphic phantom. EBT films and TLDs were used for dose comparisons and range scan of the beam distal fall-off was used as ground truth for range verification. Results: For in-vivo dose measurement, the results were in agreement with TLD and EBT films and were within 3% from treatment planning calculations. For range verification, a precision of 0.5mm is achieved in homogeneous phantoms, and a precision of 2mm for anthropomorphic pelvic phantom, except at points with significant range mixing. Conclusion: We completed the commissioning of our system for in-vivo dosimetry and range verification in proton therapy. The results suggest that the system is ready for clinical trials on patient.« less

  14. NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR FREEZER MAINTENANCE AND TEMPERATURE VERIFICATION FOR SAMPLE INTEGRITY (BCO-L-25.0)

    EPA Science Inventory

    The purpose of this SOP is to ensure suitable temperature maintenance of freezers used for storage of samples. This procedure was followed to ensure consistent data retrieval during the Arizona NHEXAS project and the "Border" study. Keywords: freezers; operation.

    The National H...

  15. NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR MAINTENANCE AND TEMPERATURE VERIFICATION OF REFRIGERATED UNITS FOR SAMPLE STORAGE (UA-L-4.1)

    EPA Science Inventory

    The purpose of this SOP is to assure suitable temperature maintenance in refrigerators and freezers used for sample storage during the Arizona NHEXAS project and the "Border" study. Keywords: lab; equipment; refrigerators and freezers.

    The National Human Exposure Assessment Su...

  16. CLSI-based transference and verification of CALIPER pediatric reference intervals for 29 Ortho VITROS 5600 chemistry assays.

    PubMed

    Higgins, Victoria; Truong, Dorothy; Woroch, Amy; Chan, Man Khun; Tahmasebi, Houman; Adeli, Khosrow

    2018-03-01

    Evidence-based reference intervals (RIs) are essential to accurately interpret pediatric laboratory test results. To fill gaps in pediatric RIs, the Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER) project developed an age- and sex-specific pediatric RI database based on healthy pediatric subjects. Originally established for Abbott ARCHITECT assays, CALIPER RIs were transferred to assays on Beckman, Roche, Siemens, and Ortho analytical platforms. This study provides transferred reference intervals for 29 biochemical assays for the Ortho VITROS 5600 Chemistry System (Ortho). Based on Clinical Laboratory Standards Institute (CLSI) guidelines, a method comparison analysis was performed by measuring approximately 200 patient serum samples using Abbott and Ortho assays. The equation of the line of best fit was calculated and the appropriateness of the linear model was assessed. This equation was used to transfer RIs from Abbott to Ortho assays. Transferred RIs were verified using 84 healthy pediatric serum samples from the CALIPER cohort. RIs for most chemistry analytes successfully transferred from Abbott to Ortho assays. Calcium and CO 2 did not meet statistical criteria for transference (r 2 <0.70). Of the 32 transferred reference intervals, 29 successfully verified with approximately 90% of results from reference samples falling within transferred confidence limits. Transferred RIs for total bilirubin, magnesium, and LDH did not meet verification criteria and are not reported. This study broadens the utility of the CALIPER pediatric RI database to laboratories using Ortho VITROS 5600 biochemical assays. Clinical laboratories should verify CALIPER reference intervals for their specific analytical platform and local population as recommended by CLSI. Copyright © 2018 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  17. Verification testing of the compression performance of the HEVC screen content coding extensions

    NASA Astrophysics Data System (ADS)

    Sullivan, Gary J.; Baroncini, Vittorio A.; Yu, Haoping; Joshi, Rajan L.; Liu, Shan; Xiu, Xiaoyu; Xu, Jizheng

    2017-09-01

    This paper reports on verification testing of the coding performance of the screen content coding (SCC) extensions of the High Efficiency Video Coding (HEVC) standard (Rec. ITU-T H.265 | ISO/IEC 23008-2 MPEG-H Part 2). The coding performance of HEVC screen content model (SCM) reference software is compared with that of the HEVC test model (HM) without the SCC extensions, as well as with the Advanced Video Coding (AVC) joint model (JM) reference software, for both lossy and mathematically lossless compression using All-Intra (AI), Random Access (RA), and Lowdelay B (LB) encoding structures and using similar encoding techniques. Video test sequences in 1920×1080 RGB 4:4:4, YCbCr 4:4:4, and YCbCr 4:2:0 colour sampling formats with 8 bits per sample are tested in two categories: "text and graphics with motion" (TGM) and "mixed" content. For lossless coding, the encodings are evaluated in terms of relative bit-rate savings. For lossy compression, subjective testing was conducted at 4 quality levels for each coding case, and the test results are presented through mean opinion score (MOS) curves. The relative coding performance is also evaluated in terms of Bjøntegaard-delta (BD) bit-rate savings for equal PSNR quality. The perceptual tests and objective metric measurements show a very substantial benefit in coding efficiency for the SCC extensions, and provided consistent results with a high degree of confidence. For TGM video, the estimated bit-rate savings ranged from 60-90% relative to the JM and 40-80% relative to the HM, depending on the AI/RA/LB configuration category and colour sampling format.

  18. Towards real-time VMAT verification using a prototype, high-speed CMOS active pixel sensor.

    PubMed

    Zin, Hafiz M; Harris, Emma J; Osmond, John P F; Allinson, Nigel M; Evans, Philip M

    2013-05-21

    This work investigates the feasibility of using a prototype complementary metal oxide semiconductor active pixel sensor (CMOS APS) for real-time verification of volumetric modulated arc therapy (VMAT) treatment. The prototype CMOS APS used region of interest read out on the chip to allow fast imaging of up to 403.6 frames per second (f/s). The sensor was made larger (5.4 cm × 5.4 cm) using recent advances in photolithographic technique but retains fast imaging speed with the sensor's regional read out. There is a paradigm shift in radiotherapy treatment verification with the advent of advanced treatment techniques such as VMAT. This work has demonstrated that the APS can track multi leaf collimator (MLC) leaves moving at 18 mm s(-1) with an automatic edge tracking algorithm at accuracy better than 1.0 mm even at the fastest imaging speed. Evaluation of the measured fluence distribution for an example VMAT delivery sampled at 50.4 f/s was shown to agree well with the planned fluence distribution, with an average gamma pass rate of 96% at 3%/3 mm. The MLC leaves motion and linac pulse rate variation delivered throughout the VMAT treatment can also be measured. The results demonstrate the potential of CMOS APS technology as a real-time radiotherapy dosimeter for delivery of complex treatments such as VMAT.

  19. Compliance and Verification of Standards and Labelling Programs in China: Lessons Learned

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saheb, Yamina; Zhou, Nan; Fridley, David

    2010-06-11

    After implementing several energy efficiency standards and labels (30 products covered by MEPS, 50 products covered by voluntary labels and 19 products by mandatory labels), the China National Institute of Standardization (CNIS) is now implementing verification and compliance mechanism to ensure that the energy information of labeled products comply with the requirements of their labels. CNIS is doing so by organizing check testing on a random basis for room air-conditioners, refrigerators, motors, heaters, computer displays, ovens, and self -ballasted lamps. The purpose of the check testing is to understand the implementation of the Chinese labeling scheme and help local authoritiesmore » establishing effective compliance mechanisms. In addition, to ensure robustness and consistency of testing results, CNIS has coordinated a round robin testing for room air conditioners. Eight laboratories (Chinese (6), Australian (1) and Japanese (1)) have been involved in the round robin testing and tests were performed on four sets of samples selected from manufacturer?s production line. This paper describes the methodology used in undertaking both check and round robin testing, provides analysis of testing results and reports on the findings. The analysis of both check and round robin testing demonstrated the benefits of a regularized verification and monitoring system for both laboratories and products such as (i) identifying the possible deviations between laboratories to correct them, (ii) improving the quality of testing facilities, (iii) ensuring the accuracy and reliability of energy label information in order to strength the social credibility of the labeling program and the enforcement mechanism in place.« less

  20. Compliance and Verification of Standards and Labeling Programs in China: Lessons Learned

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saheb, Yamina; Zhou, Nan; Fridley, David

    2010-08-01

    After implementing several energy efficiency standards and labels (30 products covered by MEPS, 50 products covered by voluntary labels and 19 products by mandatory labels), the China National Institute of Standardization (CNIS) is now implementing verification and compliance mechanism to ensure that the energy information of labeled products comply with the requirements of their labels. CNIS is doing so by organizing check testing on a random basis for room air-conditioners, refrigerators, motors, heaters, computer displays, ovens, and self -ballasted lamps. The purpose of the check testing is to understand the implementation of the Chinese labeling scheme and help local authoritiesmore » establishing effective compliance mechanisms. In addition, to ensure robustness and consistency of testing results, CNIS has coordinated a round robin testing for room air conditioners. Eight laboratories (Chinese (6), Australian (1) and Japanese (1)) have been involved in the round robin testing and tests were performed on four sets of samples selected from manufacturer's production line. This paper describes the methodology used in undertaking both check and round robin testing, provides analysis of testing results and reports on the findings. The analysis of both check and round robin testing demonstrated the benefits of a regularized verification and monitoring system for both laboratories and products such as (i) identifying the possible deviations between laboratories to correct them, (ii) improving the quality of testing facilities, (iii) ensuring the accuracy and reliability of energy label information in order to strength the social credibility of the labeling program and the enforcement mechanism in place.« less

  1. An Overview and Empirical Comparison of Distance Metric Learning Methods.

    PubMed

    Moutafis, Panagiotis; Leng, Mengjun; Kakadiaris, Ioannis A

    2016-02-16

    In this paper, we first offer an overview of advances in the field of distance metric learning. Then, we empirically compare selected methods using a common experimental protocol. The number of distance metric learning algorithms proposed keeps growing due to their effectiveness and wide application. However, existing surveys are either outdated or they focus only on a few methods. As a result, there is an increasing need to summarize the obtained knowledge in a concise, yet informative manner. Moreover, existing surveys do not conduct comprehensive experimental comparisons. On the other hand, individual distance metric learning papers compare the performance of the proposed approach with only a few related methods and under different settings. This highlights the need for an experimental evaluation using a common and challenging protocol. To this end, we conduct face verification experiments, as this task poses significant challenges due to varying conditions during data acquisition. In addition, face verification is a natural application for distance metric learning because the encountered challenge is to define a distance function that: 1) accurately expresses the notion of similarity for verification; 2) is robust to noisy data; 3) generalizes well to unseen subjects; and 4) scales well with the dimensionality and number of training samples. In particular, we utilize well-tested features to assess the performance of selected methods following the experimental protocol of the state-of-the-art database labeled faces in the wild. A summary of the results is presented along with a discussion of the insights obtained and lessons learned by employing the corresponding algorithms.

  2. A comparison of QuantStudio™ 3D Digital PCR and ARMS-PCR for measuring plasma EGFR T790M mutations of NSCLC patients

    PubMed Central

    Sang, Yaxiong; Zhang, Jie; Wang, Ping; Wang, Yue; Liu, Bing; Lin, Dongmei; Yu, Yang; Fang, Jian

    2018-01-01

    Background The AURA3 clinical trial has shown that advanced non-small cell lung cancer (NSCLC) patients with EGFR T790M mutations in circulating tumor DNA (ctDNA) could benefit from osimertinib. Purpose The aim of this study was to assess the usefulness of QuantStudio™ 3D Digital PCR System platform for the detection of plasma EGFR T790M mutations in NSCLC patients, and compare the performances of 3D Digital PCR and ARMS-PCR. Patients and methods A total of 119 Chinese patients were enrolled in this study. Mutant allele frequency of plasma EGFR T790M was detected by 3D Digital PCR, then 25 selected samples were verified by ARMS-PCR and four of them were verified by next generation sequencing (NGS). Results In total, 52.94% (69/119) had EGFR T790M mutations detected by 3D Digital PCR. In 69 positive samples, the median mutant allele frequency (AF) was 1.09% and three cases presented low concentration (AF <0.1%). Limited by the amount of plasma DNA, 17 samples (AF <2.5%) and eight samples (T790M-) were selected for verification by ARMS-PCR. Four of those samples were verified by NGS as a third verification method. Among the selected 17 positive cases, ten samples presented mutant allele frequency <0.5%, and seven samples presented intermediate mutant allele frequency (0.5% AF 2.5%). However, only three samples (3/17) were identified as positive by ARMS-PCR, namely, P6 (AF =1.09%), P7 (AF =2.09%), and P8 (AF =2.21%). It is worth mentioning that sample P9 (AF =2.05%, analyzed by 3D Digital PCR) was identified as T790M- by ARMS-PCR. Four samples were identified as T790M+ by both NGS and 3D Digital PCR, and typically three samples (3/4) presented at a low ratio (AF <0.5%). Conclusion Our study demonstrated that 3D Digital PCR is a novel method with high sensitivity and specificity to detect EGFR T790M mutation in plasma. PMID:29403309

  3. Enrichment Assay Methods Development for the Integrated Cylinder Verification System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, Leon E.; Misner, Alex C.; Hatchell, Brian K.

    2009-10-22

    International Atomic Energy Agency (IAEA) inspectors currently perform periodic inspections at uranium enrichment plants to verify UF6 cylinder enrichment declarations. Measurements are typically performed with handheld high-resolution sensors on a sampling of cylinders taken to be representative of the facility's entire product-cylinder inventory. Pacific Northwest National Laboratory (PNNL) is developing a concept to automate the verification of enrichment plant cylinders to enable 100 percent product-cylinder verification and potentially, mass-balance calculations on the facility as a whole (by also measuring feed and tails cylinders). The Integrated Cylinder Verification System (ICVS) could be located at key measurement points to positively identify eachmore » cylinder, measure its mass and enrichment, store the collected data in a secure database, and maintain continuity of knowledge on measured cylinders until IAEA inspector arrival. The three main objectives of this FY09 project are summarized here and described in more detail in the report: (1) Develop a preliminary design for a prototype NDA system, (2) Refine PNNL's MCNP models of the NDA system, and (3) Procure and test key pulse-processing components. Progress against these tasks to date, and next steps, are discussed.« less

  4. Development of CFC-Free Cleaning Processes at the NASA White Sands Test Facility

    NASA Technical Reports Server (NTRS)

    Beeson, Harold; Kirsch, Mike; Hornung, Steven; Biesinger, Paul

    1995-01-01

    The NASA White Sands Test Facility (WSTF) is developing cleaning and verification processes to replace currently used chlorofluorocarbon-113- (CFC-113-) based processes. The processes being evaluated include both aqueous- and solvent-based techniques. The presentation will include the findings of investigations of aqueous cleaning and verification processes that are based on a draft of a proposed NASA Kennedy Space Center (KSC) cleaning procedure. Verification testing with known contaminants, such as hydraulic fluid and commonly used oils, established correlations between nonvolatile residue and CFC-113. Recoveries ranged from 35 to 60 percent of theoretical. WSTF is also investigating enhancements to aqueous sampling for organics and particulates. Although aqueous alternatives have been identified for several processes, a need still exists for nonaqueous solvent cleaning, such as the cleaning and cleanliness verification of gauges used for oxygen service. The cleaning effectiveness of tetrachloroethylene (PCE), trichloroethylene (TCE), ethanol, hydrochlorofluorocarbon-225 (HCFC-225), tert-butylmethylether, and n-Hexane was evaluated using aerospace gauges and precision instruments and then compared to the cleaning effectiveness of CFC-113. Solvents considered for use in oxygen systems were also tested for oxygen compatibility using high-pressure oxygen autoignition and liquid oxygen mechanical impact testing.

  5. Cognitive Bias in the Verification and Validation of Space Flight Systems

    NASA Technical Reports Server (NTRS)

    Larson, Steve

    2012-01-01

    Cognitive bias is generally recognized as playing a significant role in virtually all domains of human decision making. Insight into this role is informally built into many of the system engineering practices employed in the aerospace industry. The review process, for example, typically has features that help to counteract the effect of bias. This paper presents a discussion of how commonly recognized biases may affect the verification and validation process. Verifying and validating a system is arguably more challenging than development, both technically and cognitively. Whereas there may be a relatively limited number of options available for the design of a particular aspect of a system, there is a virtually unlimited number of potential verification scenarios that may be explored. The probability of any particular scenario occurring in operations is typically very difficult to estimate, which increases reliance on judgment that may be affected by bias. Implementing a verification activity often presents technical challenges that, if they can be overcome at all, often result in a departure from actual flight conditions (e.g., 1-g testing, simulation, time compression, artificial fault injection) that may raise additional questions about the meaningfulness of the results, and create opportunities for the introduction of additional biases. In addition to mitigating the biases it can introduce directly, the verification and validation process must also overcome the cumulative effect of biases introduced during all previous stages of development. A variety of cognitive biases will be described, with research results for illustration. A handful of case studies will be presented that show how cognitive bias may have affected the verification and validation process on recent JPL flight projects, identify areas of strength and weakness, and identify potential changes or additions to commonly used techniques that could provide a more robust verification and validation of future systems.

  6. A study of applications scribe frame data verifications using design rule check

    NASA Astrophysics Data System (ADS)

    Saito, Shoko; Miyazaki, Masaru; Sakurai, Mitsuo; Itoh, Takahisa; Doi, Kazumasa; Sakurai, Norioko; Okada, Tomoyuki

    2013-06-01

    In semiconductor manufacturing, scribe frame data generally is generated for each LSI product according to its specific process design. Scribe frame data is designed based on definition tables of scanner alignment, wafer inspection and customers specified marks. We check that scribe frame design is conforming to specification of alignment and inspection marks at the end. Recently, in COT (customer owned tooling) business or new technology development, there is no effective verification method for the scribe frame data, and we take a lot of time to work on verification. Therefore, we tried to establish new verification method of scribe frame data by applying pattern matching and DRC (Design Rule Check) which is used in device verification. We would like to show scheme of the scribe frame data verification using DRC which we tried to apply. First, verification rules are created based on specifications of scanner, inspection and others, and a mark library is also created for pattern matching. Next, DRC verification is performed to scribe frame data. Then the DRC verification includes pattern matching using mark library. As a result, our experiments demonstrated that by use of pattern matching and DRC verification our new method can yield speed improvements of more than 12 percent compared to the conventional mark checks by visual inspection and the inspection time can be reduced to less than 5 percent if multi-CPU processing is used. Our method delivers both short processing time and excellent accuracy when checking many marks. It is easy to maintain and provides an easy way for COT customers to use original marks. We believe that our new DRC verification method for scribe frame data is indispensable and mutually beneficial.

  7. Block 2 SRM conceptual design studies. Volume 1, Book 2: Preliminary development and verification plan

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Activities that will be conducted in support of the development and verification of the Block 2 Solid Rocket Motor (SRM) are described. Development includes design, fabrication, processing, and testing activities in which the results are fed back into the project. Verification includes analytical and test activities which demonstrate SRM component/subassembly/assembly capability to perform its intended function. The management organization responsible for formulating and implementing the verification program is introduced. It also identifies the controls which will monitor and track the verification program. Integral with the design and certification of the SRM are other pieces of equipment used in transportation, handling, and testing which influence the reliability and maintainability of the SRM configuration. The certification of this equipment is also discussed.

  8. SU-F-T-494: A Multi-Institutional Study of Independent Dose Verification Using Golden Beam Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Itano, M; Yamazaki, T; Tachibana, R

    Purpose: In general, beam data of individual linac is measured for independent dose verification software program and the verification is performed as a secondary check. In this study, independent dose verification using golden beam data was compared to that using individual linac’s beam data. Methods: Six institutions were participated and three different beam data were prepared. The one was individual measured data (Original Beam Data, OBD) .The others were generated by all measurements from same linac model (Model-GBD) and all linac models (All-GBD). The three different beam data were registered to the independent verification software program for each institute. Subsequently,more » patient’s plans in eight sites (brain, head and neck, lung, esophagus, breast, abdomen, pelvis and bone) were analyzed using the verification program to compare doses calculated using the three different beam data. Results: 1116 plans were collected from six institutes. Compared to using the OBD, the results shows the variation using the Model-GBD based calculation and the All-GBD was 0.0 ± 0.3% and 0.0 ± 0.6%, respectively. The maximum variations were 1.2% and 2.3%, respectively. The plans with the variation over 1% shows the reference points were located away from the central axis with/without physical wedge. Conclusion: The confidence limit (2SD) using the Model-GBD and the All-GBD was within 0.6% and 1.2%, respectively. Thus, the use of golden beam data may be feasible for independent verification. In addition to it, the verification using golden beam data provide quality assurance of planning from the view of audit. This research is partially supported by Japan Agency for Medical Research and Development(AMED)« less

  9. A service-oriented architecture for integrating the modeling and formal verification of genetic regulatory networks

    PubMed Central

    2009-01-01

    Background The study of biological networks has led to the development of increasingly large and detailed models. Computer tools are essential for the simulation of the dynamical behavior of the networks from the model. However, as the size of the models grows, it becomes infeasible to manually verify the predictions against experimental data or identify interesting features in a large number of simulation traces. Formal verification based on temporal logic and model checking provides promising methods to automate and scale the analysis of the models. However, a framework that tightly integrates modeling and simulation tools with model checkers is currently missing, on both the conceptual and the implementational level. Results We have developed a generic and modular web service, based on a service-oriented architecture, for integrating the modeling and formal verification of genetic regulatory networks. The architecture has been implemented in the context of the qualitative modeling and simulation tool GNA and the model checkers NUSMV and CADP. GNA has been extended with a verification module for the specification and checking of biological properties. The verification module also allows the display and visual inspection of the verification results. Conclusions The practical use of the proposed web service is illustrated by means of a scenario involving the analysis of a qualitative model of the carbon starvation response in E. coli. The service-oriented architecture allows modelers to define the model and proceed with the specification and formal verification of the biological properties by means of a unified graphical user interface. This guarantees a transparent access to formal verification technology for modelers of genetic regulatory networks. PMID:20042075

  10. Offline signature verification using convolution Siamese network

    NASA Astrophysics Data System (ADS)

    Xing, Zi-Jian; Yin, Fei; Wu, Yi-Chao; Liu, Cheng-Lin

    2018-04-01

    This paper presents an offline signature verification approach using convolutional Siamese neural network. Unlike the existing methods which consider feature extraction and metric learning as two independent stages, we adopt a deepleaning based framework which combines the two stages together and can be trained end-to-end. The experimental results on two offline public databases (GPDSsynthetic and CEDAR) demonstrate the superiority of our method on the offline signature verification problem.

  11. A framework of multitemplate ensemble for fingerprint verification

    NASA Astrophysics Data System (ADS)

    Yin, Yilong; Ning, Yanbin; Ren, Chunxiao; Liu, Li

    2012-12-01

    How to improve performance of an automatic fingerprint verification system (AFVS) is always a big challenge in biometric verification field. Recently, it becomes popular to improve the performance of AFVS using ensemble learning approach to fuse related information of fingerprints. In this article, we propose a novel framework of fingerprint verification which is based on the multitemplate ensemble method. This framework is consisted of three stages. In the first stage, enrollment stage, we adopt an effective template selection method to select those fingerprints which best represent a finger, and then, a polyhedron is created by the matching results of multiple template fingerprints and a virtual centroid of the polyhedron is given. In the second stage, verification stage, we measure the distance between the centroid of the polyhedron and a query image. In the final stage, a fusion rule is used to choose a proper distance from a distance set. The experimental results on the FVC2004 database prove the improvement on the effectiveness of the new framework in fingerprint verification. With a minutiae-based matching method, the average EER of four databases in FVC2004 drops from 10.85 to 0.88, and with a ridge-based matching method, the average EER of these four databases also decreases from 14.58 to 2.51.

  12. Mitigating errors caused by interruptions during medication verification and administration: interventions in a simulated ambulatory chemotherapy setting

    PubMed Central

    Prakash, Varuna; Koczmara, Christine; Savage, Pamela; Trip, Katherine; Stewart, Janice; McCurdie, Tara; Cafazzo, Joseph A; Trbovich, Patricia

    2014-01-01

    Background Nurses are frequently interrupted during medication verification and administration; however, few interventions exist to mitigate resulting errors, and the impact of these interventions on medication safety is poorly understood. Objective The study objectives were to (A) assess the effects of interruptions on medication verification and administration errors, and (B) design and test the effectiveness of targeted interventions at reducing these errors. Methods The study focused on medication verification and administration in an ambulatory chemotherapy setting. A simulation laboratory experiment was conducted to determine interruption-related error rates during specific medication verification and administration tasks. Interventions to reduce these errors were developed through a participatory design process, and their error reduction effectiveness was assessed through a postintervention experiment. Results Significantly more nurses committed medication errors when interrupted than when uninterrupted. With use of interventions when interrupted, significantly fewer nurses made errors in verifying medication volumes contained in syringes (16/18; 89% preintervention error rate vs 11/19; 58% postintervention error rate; p=0.038; Fisher's exact test) and programmed in ambulatory pumps (17/18; 94% preintervention vs 11/19; 58% postintervention; p=0.012). The rate of error commission significantly decreased with use of interventions when interrupted during intravenous push (16/18; 89% preintervention vs 6/19; 32% postintervention; p=0.017) and pump programming (7/18; 39% preintervention vs 1/19; 5% postintervention; p=0.017). No statistically significant differences were observed for other medication verification tasks. Conclusions Interruptions can lead to medication verification and administration errors. Interventions were highly effective at reducing unanticipated errors of commission in medication administration tasks, but showed mixed effectiveness at reducing predictable errors of detection in medication verification tasks. These findings can be generalised and adapted to mitigate interruption-related errors in other settings where medication verification and administration are required. PMID:24906806

  13. Influence of the Redundant Verification and the Non-Redundant Verification on the Hydraulic Tomography

    NASA Astrophysics Data System (ADS)

    Wei, T. B.; Chen, Y. L.; Lin, H. R.; Huang, S. Y.; Yeh, T. C. J.; Wen, J. C.

    2016-12-01

    In the groundwater study, it estimated the heterogeneous spatial distribution of hydraulic Properties, there were many scholars use to hydraulic tomography (HT) from field site pumping tests to estimate inverse of heterogeneous spatial distribution of hydraulic Properties, to prove the most of most field site aquifer was heterogeneous hydrogeological parameters spatial distribution field. Many scholars had proposed a method of hydraulic tomography to estimate heterogeneous spatial distribution of hydraulic Properties of aquifer, the Huang et al. [2011] was used the non-redundant verification analysis of pumping wells changed, observation wells fixed on the inverse and the forward, to reflect the feasibility of the heterogeneous spatial distribution of hydraulic Properties of field site aquifer of the non-redundant verification analysis on steady-state model.From post literature, finding only in steady state, non-redundant verification analysis of pumping well changed location and observation wells fixed location for inverse and forward. But the studies had not yet pumping wells fixed or changed location, and observation wells fixed location for redundant verification or observation wells change location for non-redundant verification of the various combinations may to explore of influences of hydraulic tomography method. In this study, it carried out redundant verification method and non-redundant verification method for forward to influences of hydraulic tomography method in transient. And it discuss above mentioned in NYUST campus sites the actual case, to prove the effectiveness of hydraulic tomography methods, and confirmed the feasibility on inverse and forward analysis from analysis results.Keywords: Hydraulic Tomography, Redundant Verification, Heterogeneous, Inverse, Forward

  14. Verification and validation of RADMODL Version 1.0

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kimball, K.D.

    1993-03-01

    RADMODL is a system of linked computer codes designed to calculate the radiation environment following an accident in which nuclear materials are released. The RADMODL code and the corresponding Verification and Validation (V&V) calculations (Appendix A), were developed for Westinghouse Savannah River Company (WSRC) by EGS Corporation (EGS). Each module of RADMODL is an independent code and was verified separately. The full system was validated by comparing the output of the various modules with the corresponding output of a previously verified version of the modules. The results of the verification and validation tests show that RADMODL correctly calculates the transportmore » of radionuclides and radiation doses. As a result of this verification and validation effort, RADMODL Version 1.0 is certified for use in calculating the radiation environment following an accident.« less

  15. SU-F-T-269: Preliminary Experience of Kuwait Cancer Control Center (KCCC) On IMRT Treatment Planning and Pre-Treatment Verification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sethuraman, TKR; Sherif, M; Subramanian, N

    Purpose: The complexity of IMRT delivery requires pre-treatment quality assurance and plan verification. KCCC has implemented IMRT clinically in few sites and will extend to all sites. Recently, our Varian linear accelerator and Eclipse planning system were upgraded from Millennium 80 to 120 Multileaf Collimator (MLC) and from v8.6 to 11.0 respectively. Our preliminary experience on the pre-treatment quality assurance verification is discussed. Methods: Eight Breast, Three Prostate and One Hypopharynx cancer patients were planned with step and shoot IMRT. All breast cases were planned before the upgrade with 60% cases treated. The ICRU 83 recommendations were followed for themore » dose prescription and constraints to OAR for all cases. Point dose measurement was done with CIRS cylindrical phantom and PTW 0.125 cc ionization chamber. Measured dose was compared with calculated dose at the point of measurement. Map CHECK diode array phantom was used for the plan verification. Planned and measured doses were compared by applying gamma index of 3% (dose difference) / 3 mm DTA (average distance to agreement). For all cases, a plan is considered to be successful if more than 95% of the tested diodes pass the gamma test. A prostate case was chosen to compare the plan verification before and after the upgrade. Results: Point dose measurement results were in agreement with the calculated doses. The maximum deviation observed was 2.3%. The passing rate of average gamma index was measured higher than 97% for the plan verification of all cases. Similar result was observed for plan verification of the chosen prostate case before and after the upgrade. Conclusion: Our preliminary experience from the obtained results validates the accuracy of our QA process and provides confidence to extend IMRT to all sites in Kuwait.« less

  16. Area of Concern (AOC) 314 Verification Survey at Former McClellan AFB, Sacramento, CA

    DTIC Science & Technology

    2015-03-31

    also collected 22 soil samples from within AOC 314. Laboratory analysis revealed that the concentration of radium-226 (Ra-226) in 10 of the soil ...at least one sample that exceeded 2.0 pCi/g. The highest concentration of Ra-226 found in any of the soil samples was 25.8 pCi/g. Based on these...and ensure the potential health risk to future inhabitants is minimized. USAFSAM/OEC personnel also collected 22 soil samples from within AOC 314

  17. Category V Compliant Container for Mars Sample Return Missions

    NASA Technical Reports Server (NTRS)

    Dolgin, Benjamin; Sanok, Joseph; Sevilla, Donald; Bement, Laurence J.

    2000-01-01

    A novel containerization technique that satisfies Planetary Protection (PP) Category V requirements has been developed and demonstrated on the mock-up of the Mars Sample Return Container. The proposed approach uses explosive welding with a sacrificial layer and cut-through-the-seam techniques. The technology produces a container that is free from Martian contaminants on an atomic level. The containerization technique can be used on any celestial body that may support life. A major advantage of the proposed technology is the possibility of very fast (less than an hour) verification of both containment and cleanliness with typical metallurgical laboratory equipment. No separate biological verification is required. In addition to Category V requirements, the proposed container presents a surface that is clean from any, even nonviable organisms, and any molecular fragments of biological origin that are unique to Mars or any other celestial body other than Earth.

  18. Numerical analysis and experimental verification of elastomer bending process with different material models

    NASA Astrophysics Data System (ADS)

    Kut, Stanislaw; Ryzinska, Grazyna; Niedzialek, Bernadetta

    2016-01-01

    The article presents the results of tests in order to verifying the effectiveness of the nine selected elastomeric material models (Neo-Hookean, Mooney with two and three constants, Signorini, Yeoh, Ogden, Arruda-Boyce, Gent and Marlow), which the material constants were determined in one material test - the uniaxial tension testing. The convergence assessment of nine analyzed models were made on the basis of their performance from an experimental bending test of the elastomer samples from the results of numerical calculations FEM for each material models. To calculate the material constants for the analyzed materials, a model has been generated by the stressstrain characteristics created as a result of experimental uniaxial tensile test with elastomeric dumbbell samples, taking into account the parameters received in its 18th cycle. Using such a calculated material constants numerical simulation of the bending process of a elastomeric, parallelepipedic sampleswere carried out using MARC / Mentat program.

  19. SNP Data Quality Control in a National Beef and Dairy Cattle System and Highly Accurate SNP Based Parentage Verification and Identification

    PubMed Central

    McClure, Matthew C.; McCarthy, John; Flynn, Paul; McClure, Jennifer C.; Dair, Emma; O'Connell, D. K.; Kearney, John F.

    2018-01-01

    A major use of genetic data is parentage verification and identification as inaccurate pedigrees negatively affect genetic gain. Since 2012 the international standard for single nucleotide polymorphism (SNP) verification in Bos taurus cattle has been the ISAG SNP panels. While these ISAG panels provide an increased level of parentage accuracy over microsatellite markers (MS), they can validate the wrong parent at ≤1% misconcordance rate levels, indicating that more SNP are needed if a more accurate pedigree is required. With rapidly increasing numbers of cattle being genotyped in Ireland that represent 61 B. taurus breeds from a wide range of farm types: beef/dairy, AI/pedigree/commercial, purebred/crossbred, and large to small herd size the Irish Cattle Breeding Federation (ICBF) analyzed different SNP densities to determine that at a minimum ≥500 SNP are needed to consistently predict only one set of parents at a ≤1% misconcordance rate. For parentage validation and prediction ICBF uses 800 SNP (ICBF800) selected based on SNP clustering quality, ISAG200 inclusion, call rate (CR), and minor allele frequency (MAF) in the Irish cattle population. Large datasets require sample and SNP quality control (QC). Most publications only deal with SNP QC via CR, MAF, parent-progeny conflicts, and Hardy-Weinberg deviation, but not sample QC. We report here parentage, SNP QC, and a genomic sample QC pipelines to deal with the unique challenges of >1 million genotypes from a national herd such as SNP genotype errors from mis-tagging of animals, lab errors, farm errors, and multiple other issues that can arise. We divide the pipeline into two parts: a Genotype QC and an Animal QC pipeline. The Genotype QC identifies samples with low call rate, missing or mixed genotype classes (no BB genotype or ABTG alleles present), and low genotype frequencies. The Animal QC handles situations where the genotype might not belong to the listed individual by identifying: >1 non-matching genotypes per animal, SNP duplicates, sex and breed prediction mismatches, parentage and progeny validation results, and other situations. The Animal QC pipeline make use of ICBF800 SNP set where appropriate to identify errors in a computationally efficient yet still highly accurate method. PMID:29599798

  20. Electric power system test and verification program

    NASA Technical Reports Server (NTRS)

    Rylicki, Daniel S.; Robinson, Frank, Jr.

    1994-01-01

    Space Station Freedom's (SSF's) electric power system (EPS) hardware and software verification is performed at all levels of integration, from components to assembly and system level tests. Careful planning is essential to ensure the EPS is tested properly on the ground prior to launch. The results of the test performed on breadboard model hardware and analyses completed to date have been evaluated and used to plan for design qualification and flight acceptance test phases. These results and plans indicate the verification program for SSF's 75-kW EPS would have been successful and completed in time to support the scheduled first element launch.

  1. Time-space modal logic for verification of bit-slice circuits

    NASA Astrophysics Data System (ADS)

    Hiraishi, Hiromi

    1996-03-01

    The major goal of this paper is to propose a new modal logic aiming at formal verification of bit-slice circuits. The new logic is called as time-space modal logic and its major feature is that it can handle two transition relations: one for time transition and the other for space transition. As for a verification algorithm, a symbolic model checking algorithm of the new logic is shown. This could be applicable to verification of bit-slice microprocessor of infinite bit width and 1D systolic array of infinite length. A simple benchmark result shows the effectiveness of the proposed approach.

  2. A methodology for the rigorous verification of plasma simulation codes

    NASA Astrophysics Data System (ADS)

    Riva, Fabio

    2016-10-01

    The methodology used to assess the reliability of numerical simulation codes constitutes the Verification and Validation (V&V) procedure. V&V is composed by two separate tasks: the verification, which is a mathematical issue targeted to assess that the physical model is correctly solved, and the validation, which determines the consistency of the code results, and therefore of the physical model, with experimental data. In the present talk we focus our attention on the verification, which in turn is composed by the code verification, targeted to assess that a physical model is correctly implemented in a simulation code, and the solution verification, that quantifies the numerical error affecting a simulation. Bridging the gap between plasma physics and other scientific domains, we introduced for the first time in our domain a rigorous methodology for the code verification, based on the method of manufactured solutions, as well as a solution verification based on the Richardson extrapolation. This methodology was applied to GBS, a three-dimensional fluid code based on a finite difference scheme, used to investigate the plasma turbulence in basic plasma physics experiments and in the tokamak scrape-off layer. Overcoming the difficulty of dealing with a numerical method intrinsically affected by statistical noise, we have now generalized the rigorous verification methodology to simulation codes based on the particle-in-cell algorithm, which are employed to solve Vlasov equation in the investigation of a number of plasma physics phenomena.

  3. U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--STANDARD OPERATING PROCEDURE FOR MAINTENANCE AND TEMPERATURE VERIFICATION OF REFRIGERATED UNITS FOR SAMPLE STORAGE (UA-L-4.1)

    EPA Science Inventory

    The purpose of this SOP is to assure suitable temperature maintenance in refrigerators and freezers used for sample storage during the Arizona NHEXAS project and the Border study. Keywords: lab; equipment; refrigerators and freezers.

    The U.S.-Mexico Border Program is sponsored...

  4. Transistor step stress testing program for JANTX2N2484

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The effect of power/temperature step stress when applied to the transistor JANTX2N2484, manufactured by Raytheon and Teledyne was evaluated. Forty-eight samples from each manufacturer were divided equally (16 per group) into three groups and submitted to the processes outlined. In addition, two control sample units were maintained for verification of the electrical parametric testing.

  5. Convergence between Measures of Work-to-Family and Family-to-Work Conflict: A Meta-Analytic Examination

    ERIC Educational Resources Information Center

    Mesmer-Magnus, Jessica R.; Viswesvaran, Chockalingam

    2005-01-01

    The overlap between measures of work-to-family (WFC) and family-to-work conflict (FWC) was meta-analytically investigated. Researchers have assumed WFC and FWC to be distinct, however, this assumption requires empirical verification. Across 25 independent samples (total N=9079) the sample size weighted mean observed correlation was .38 and the…

  6. Overview of the TOPEX/Poseidon Platform Harvest Verification Experiment

    NASA Technical Reports Server (NTRS)

    Morris, Charles S.; DiNardo, Steven J.; Christensen, Edward J.

    1995-01-01

    An overview is given of the in situ measurement system installed on Texaco's Platform Harvest for verification of the sea level measurement from the TOPEX/Poseidon satellite. The prelaunch error budget suggested that the total root mean square (RMS) error due to measurements made at this verification site would be less than 4 cm. The actual error budget for the verification site is within these original specifications. However, evaluation of the sea level data from three measurement systems at the platform has resulted in unexpectedly large differences between the systems. Comparison of the sea level measurements from the different tide gauge systems has led to a better understanding of the problems of measuring sea level in relatively deep ocean. As of May 1994, the Platform Harvest verification site has successfully supported 60 TOPEX/Poseidon overflights.

  7. Security Verification Techniques Applied to PatchLink COTS Software

    NASA Technical Reports Server (NTRS)

    Gilliam, David P.; Powell, John D.; Bishop, Matt; Andrew, Chris; Jog, Sameer

    2006-01-01

    Verification of the security of software artifacts is a challenging task. An integrated approach that combines verification techniques can increase the confidence in the security of software artifacts. Such an approach has been developed by the Jet Propulsion Laboratory (JPL) and the University of California at Davis (UC Davis). Two security verification instruments were developed and then piloted on PatchLink's UNIX Agent, a Commercial-Off-The-Shelf (COTS) software product, to assess the value of the instruments and the approach. The two instruments are the Flexible Modeling Framework (FMF) -- a model-based verification instrument (JPL), and a Property-Based Tester (UC Davis). Security properties were formally specified for the COTS artifact and then verified using these instruments. The results were then reviewed to determine the effectiveness of the approach and the security of the COTS product.

  8. Transmutation Fuel Performance Code Thermal Model Verification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gregory K. Miller; Pavel G. Medvedev

    2007-09-01

    FRAPCON fuel performance code is being modified to be able to model performance of the nuclear fuels of interest to the Global Nuclear Energy Partnership (GNEP). The present report documents the effort for verification of the FRAPCON thermal model. It was found that, with minor modifications, FRAPCON thermal model temperature calculation agrees with that of the commercial software ABAQUS (Version 6.4-4). This report outlines the methodology of the verification, code input, and calculation results.

  9. Integrating Fingerprint Verification into the Smart Card-Based Healthcare Information System

    NASA Astrophysics Data System (ADS)

    Moon, Daesung; Chung, Yongwha; Pan, Sung Bum; Park, Jin-Won

    2009-12-01

    As VLSI technology has been improved, a smart card employing 32-bit processors has been released, and more personal information such as medical, financial data can be stored in the card. Thus, it becomes important to protect personal information stored in the card. Verification of the card holder's identity using a fingerprint has advantages over the present practices of Personal Identification Numbers (PINs) and passwords. However, the computational workload of fingerprint verification is much heavier than that of the typical PIN-based solution. In this paper, we consider three strategies to implement fingerprint verification in a smart card environment and how to distribute the modules of fingerprint verification between the smart card and the card reader. We first evaluate the number of instructions of each step of a typical fingerprint verification algorithm, and estimate the execution time of several cryptographic algorithms to guarantee the security/privacy of the fingerprint data transmitted in the smart card with the client-server environment. Based on the evaluation results, we analyze each scenario with respect to the security level and the real-time execution requirements in order to implement fingerprint verification in the smart card with the client-server environment.

  10. Galaxy bias from galaxy–galaxy lensing in the DES science verification data

    DOE PAGES

    Prat, J.; Sánchez, C.; Miquel, R.; ...

    2017-09-25

    Here, we present a measurement of galaxy–galaxy lensing around a magnitude-limited (i AB < 22.5) sample of galaxies from the dark energy survey science verification (DES-SV) data. We split these lenses into three photometric-redshift bins from 0.2 to 0.8, and determine the product of the galaxy bias b and cross-correlation coefficient between the galaxy and dark matter overdensity fields r in each bin, using scales above 4 h –1 Mpc comoving, where we find the linear bias model to be valid given our current uncertainties. We compare our galaxy bias results from galaxy–galaxy lensing with those obtained from galaxy clusteringmore » and CMB lensing for the same sample of galaxies, and find our measurements to be in good agreement with those in Crocce et al., while, in the lowest redshift bin (z ~ 0.3), they show some tension with the findings in Giannantonio et al. We measure b · r to be 0.87 ± 0.11, 1.12 ± 0.16 and 1.24 ± 0.23, respectively, for the three redshift bins of width Δz = 0.2 in the range 0.2 < z < 0.8, defined with the photometric-redshift algorithm bpz. Using a different code to split the lens sample, tpz, leads to changes in the measured biases at the 10–20 per cent level, but it does not alter the main conclusion of this work: when comparing with Crocce et al. we do not find strong evidence for a cross-correlation parameter significantly below one in this galaxy sample, except possibly at the lowest redshift bin (z ~ 0.3), where we find r = 0.71 ± 0.11 when using tpz, and 0.83 ± 0.12 with bpz.« less

  11. Galaxy bias from galaxy–galaxy lensing in the DES science verification data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Prat, J.; Sánchez, C.; Miquel, R.

    Here, we present a measurement of galaxy–galaxy lensing around a magnitude-limited (i AB < 22.5) sample of galaxies from the dark energy survey science verification (DES-SV) data. We split these lenses into three photometric-redshift bins from 0.2 to 0.8, and determine the product of the galaxy bias b and cross-correlation coefficient between the galaxy and dark matter overdensity fields r in each bin, using scales above 4 h –1 Mpc comoving, where we find the linear bias model to be valid given our current uncertainties. We compare our galaxy bias results from galaxy–galaxy lensing with those obtained from galaxy clusteringmore » and CMB lensing for the same sample of galaxies, and find our measurements to be in good agreement with those in Crocce et al., while, in the lowest redshift bin (z ~ 0.3), they show some tension with the findings in Giannantonio et al. We measure b · r to be 0.87 ± 0.11, 1.12 ± 0.16 and 1.24 ± 0.23, respectively, for the three redshift bins of width Δz = 0.2 in the range 0.2 < z < 0.8, defined with the photometric-redshift algorithm bpz. Using a different code to split the lens sample, tpz, leads to changes in the measured biases at the 10–20 per cent level, but it does not alter the main conclusion of this work: when comparing with Crocce et al. we do not find strong evidence for a cross-correlation parameter significantly below one in this galaxy sample, except possibly at the lowest redshift bin (z ~ 0.3), where we find r = 0.71 ± 0.11 when using tpz, and 0.83 ± 0.12 with bpz.« less

  12. Galaxy bias from galaxy-galaxy lensing in the DES science verification data

    NASA Astrophysics Data System (ADS)

    Prat, J.; Sánchez, C.; Miquel, R.; Kwan, J.; Blazek, J.; Bonnett, C.; Amara, A.; Bridle, S. L.; Clampitt, J.; Crocce, M.; Fosalba, P.; Gaztanaga, E.; Giannantonio, T.; Hartley, W. G.; Jarvis, M.; MacCrann, N.; Percival, W. J.; Ross, A. J.; Sheldon, E.; Zuntz, J.; Abbott, T. M. C.; Abdalla, F. B.; Annis, J.; Benoit-Lévy, A.; Bertin, E.; Brooks, D.; Burke, D. L.; Carnero Rosell, A.; Carrasco Kind, M.; Carretero, J.; Castander, F. J.; da Costa, L. N.; DePoy, D. L.; Desai, S.; Diehl, H. T.; Doel, P.; Eifler, T. F.; Evrard, A. E.; Fausti Neto, A.; Flaugher, B.; Frieman, J.; Gerdes, D. W.; Goldstein, D. A.; Gruen, D.; Gruendl, R. A.; Gutierrez, G.; Honscheid, K.; James, D. J.; Kuehn, K.; Kuropatkin, N.; Lahav, O.; Lima, M.; Marshall, J. L.; Melchior, P.; Menanteau, F.; Nord, B.; Plazas, A. A.; Reil, K.; Romer, A. K.; Roodman, A.; Sanchez, E.; Scarpine, V.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, R. C.; Soares-Santos, M.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Walker, A. R.

    2018-01-01

    We present a measurement of galaxy-galaxy lensing around a magnitude-limited (iAB < 22.5) sample of galaxies from the dark energy survey science verification (DES-SV) data. We split these lenses into three photometric-redshift bins from 0.2 to 0.8, and determine the product of the galaxy bias b and cross-correlation coefficient between the galaxy and dark matter overdensity fields r in each bin, using scales above 4 h-1 Mpc comoving, where we find the linear bias model to be valid given our current uncertainties. We compare our galaxy bias results from galaxy-galaxy lensing with those obtained from galaxy clustering and CMB lensing for the same sample of galaxies, and find our measurements to be in good agreement with those in Crocce et al., while, in the lowest redshift bin (z ∼ 0.3), they show some tension with the findings in Giannantonio et al. We measure b · r to be 0.87 ± 0.11, 1.12 ± 0.16 and 1.24 ± 0.23, respectively, for the three redshift bins of width Δz = 0.2 in the range 0.2 < z < 0.8, defined with the photometric-redshift algorithm BPZ. Using a different code to split the lens sample, TPZ, leads to changes in the measured biases at the 10-20 per cent level, but it does not alter the main conclusion of this work: when comparing with Crocce et al. we do not find strong evidence for a cross-correlation parameter significantly below one in this galaxy sample, except possibly at the lowest redshift bin (z ∼ 0.3), where we find r = 0.71 ± 0.11 when using TPZ, and 0.83 ± 0.12 with BPZ.

  13. Verification and benchmark testing of the NUFT computer code

    NASA Astrophysics Data System (ADS)

    Lee, K. H.; Nitao, J. J.; Kulshrestha, A.

    1993-10-01

    This interim report presents results of work completed in the ongoing verification and benchmark testing of the NUFT (Nonisothermal Unsaturated-saturated Flow and Transport) computer code. NUFT is a suite of multiphase, multicomponent models for numerical solution of thermal and isothermal flow and transport in porous media, with application to subsurface contaminant transport problems. The code simulates the coupled transport of heat, fluids, and chemical components, including volatile organic compounds. Grid systems may be cartesian or cylindrical, with one-, two-, or fully three-dimensional configurations possible. In this initial phase of testing, the NUFT code was used to solve seven one-dimensional unsaturated flow and heat transfer problems. Three verification and four benchmarking problems were solved. In the verification testing, excellent agreement was observed between NUFT results and the analytical or quasianalytical solutions. In the benchmark testing, results of code intercomparison were very satisfactory. From these testing results, it is concluded that the NUFT code is ready for application to field and laboratory problems similar to those addressed here. Multidimensional problems, including those dealing with chemical transport, will be addressed in a subsequent report.

  14. Simultaneous determination of selected biogenic amines in alcoholic beverage samples by isotachophoretic and chromatographic methods.

    PubMed

    Jastrzębska, Aneta; Piasta, Anna; Szłyk, Edward

    2014-01-01

    A simple and useful method for the determination of biogenic amines in beverage samples based on isotachophoretic separation is described. The proposed procedure permitted simultaneous analysis of histamine, tyramine, cadaverine, putrescine, tryptamine, 2-phenylethylamine, spermine and spermidine. The data presented demonstrate the utility, simplicity, flexibility, sensitivity and environmentally friendly character of the proposed method. The precision of the method expressed as coefficient of variations varied from 0.1% to 5.9% for beverage samples, whereas recoveries varied from 91% to 101%. The results for the determination of biogenic amines were compared with an HPLC procedure based on a pre-column derivatisation reaction of biogenic amines with dansyl chloride. Furthermore, the derivatisation procedure was optimised by verification of concentration and pH of the buffer, the addition of organic solvents, reaction time and temperature.

  15. Determination of specific activity of cobalt (60Co/Co) in steel samples exposed to the atomic bomb in Hiroshima.

    PubMed

    Kimura, T; Takano, N; Iba, T; Fujita, S; Watanabe, T; Maruyama, T; Hamada, T

    1990-06-01

    Specific activity 60Co/Co in two steel samples taken at 687m S and 1295m NNW from the hypocenter was measured by gamma-ray spectrometry and neutron activation analysis. The results were, respectively, (2.64 +/- 0.38) x 10(1) and (3.09 +/- 0.48) x 10(-1) dpm/mg Co at the time of bombing, which are consistent with previous data by Hashizume et al. for steel rings on the surface of roofs of buildings. The present data are expected to serve as verification of the bomb neutron transport calculations. Content of nickel and copper in the samples, determined by colorimetric and neutron activation methods, respectively, was too small to account for any significant 60Co production by the (n,p) and (n, alpha) reactions.

  16. The MCNP6 Analytic Criticality Benchmark Suite

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, Forrest B.

    2016-06-16

    Analytical benchmarks provide an invaluable tool for verifying computer codes used to simulate neutron transport. Several collections of analytical benchmark problems [1-4] are used routinely in the verification of production Monte Carlo codes such as MCNP® [5,6]. Verification of a computer code is a necessary prerequisite to the more complex validation process. The verification process confirms that a code performs its intended functions correctly. The validation process involves determining the absolute accuracy of code results vs. nature. In typical validations, results are computed for a set of benchmark experiments using a particular methodology (code, cross-section data with uncertainties, and modeling)more » and compared to the measured results from the set of benchmark experiments. The validation process determines bias, bias uncertainty, and possibly additional margins. Verification is generally performed by the code developers, while validation is generally performed by code users for a particular application space. The VERIFICATION_KEFF suite of criticality problems [1,2] was originally a set of 75 criticality problems found in the literature for which exact analytical solutions are available. Even though the spatial and energy detail is necessarily limited in analytical benchmarks, typically to a few regions or energy groups, the exact solutions obtained can be used to verify that the basic algorithms, mathematics, and methods used in complex production codes perform correctly. The present work has focused on revisiting this benchmark suite. A thorough review of the problems resulted in discarding some of them as not suitable for MCNP benchmarking. For the remaining problems, many of them were reformulated to permit execution in either multigroup mode or in the normal continuous-energy mode for MCNP. Execution of the benchmarks in continuous-energy mode provides a significant advance to MCNP verification methods.« less

  17. Applying Monte Carlo Simulation to Launch Vehicle Design and Requirements Analysis

    NASA Technical Reports Server (NTRS)

    Hanson, J. M.; Beard, B. B.

    2010-01-01

    This Technical Publication (TP) is meant to address a number of topics related to the application of Monte Carlo simulation to launch vehicle design and requirements analysis. Although the focus is on a launch vehicle application, the methods may be applied to other complex systems as well. The TP is organized so that all the important topics are covered in the main text, and detailed derivations are in the appendices. The TP first introduces Monte Carlo simulation and the major topics to be discussed, including discussion of the input distributions for Monte Carlo runs, testing the simulation, how many runs are necessary for verification of requirements, what to do if results are desired for events that happen only rarely, and postprocessing, including analyzing any failed runs, examples of useful output products, and statistical information for generating desired results from the output data. Topics in the appendices include some tables for requirements verification, derivation of the number of runs required and generation of output probabilistic data with consumer risk included, derivation of launch vehicle models to include possible variations of assembled vehicles, minimization of a consumable to achieve a two-dimensional statistical result, recontact probability during staging, ensuring duplicated Monte Carlo random variations, and importance sampling.

  18. Classical verification of quantum circuits containing few basis changes

    NASA Astrophysics Data System (ADS)

    Demarie, Tommaso F.; Ouyang, Yingkai; Fitzsimons, Joseph F.

    2018-04-01

    We consider the task of verifying the correctness of quantum computation for a restricted class of circuits which contain at most two basis changes. This contains circuits giving rise to the second level of the Fourier hierarchy, the lowest level for which there is an established quantum advantage. We show that when the circuit has an outcome with probability at least the inverse of some polynomial in the circuit size, the outcome can be checked in polynomial time with bounded error by a completely classical verifier. This verification procedure is based on random sampling of computational paths and is only possible given knowledge of the likely outcome.

  19. A Methodology for Evaluating Artifacts Produced by a Formal Verification Process

    NASA Technical Reports Server (NTRS)

    Siminiceanu, Radu I.; Miner, Paul S.; Person, Suzette

    2011-01-01

    The goal of this study is to produce a methodology for evaluating the claims and arguments employed in, and the evidence produced by formal verification activities. To illustrate the process, we conduct a full assessment of a representative case study for the Enabling Technology Development and Demonstration (ETDD) program. We assess the model checking and satisfiabilty solving techniques as applied to a suite of abstract models of fault tolerant algorithms which were selected to be deployed in Orion, namely the TTEthernet startup services specified and verified in the Symbolic Analysis Laboratory (SAL) by TTTech. To this end, we introduce the Modeling and Verification Evaluation Score (MVES), a metric that is intended to estimate the amount of trust that can be placed on the evidence that is obtained. The results of the evaluation process and the MVES can then be used by non-experts and evaluators in assessing the credibility of the verification results.

  20. Verification of chemistry reference ranges using a simple method in sub-Saharan Africa.

    PubMed

    De Baetselier, Irith; Taylor, Douglas; Mandala, Justin; Nanda, Kavita; Van Campenhout, Christel; Agingu, Walter; Madurai, Lorna; Barsch, Eva-Maria; Deese, Jennifer; Van Damme, Lut; Crucitti, Tania

    2016-01-01

    Chemistry safety assessments are interpreted by using chemistry reference ranges (CRRs). Verification of CRRs is time consuming and often requires a statistical background. We report on an easy and cost-saving method to verify CRRs. Using a former method introduced by Sigma Diagnostics, three study sites in sub-Saharan Africa, Bondo, Kenya, and Pretoria and Bloemfontein, South Africa, verified the CRRs for hepatic and renal biochemistry assays performed during a clinical trial of HIV antiretroviral pre-exposure prophylaxis. The aspartate aminotransferase/alanine aminotransferase, creatinine and phosphorus results from 10 clinically-healthy participants at the screening visit were used. In the event the CRRs did not pass the verification, new CRRs had to be calculated based on 40 clinically-healthy participants. Within a few weeks, the study sites accomplished verification of the CRRs without additional costs. The aspartate aminotransferase reference ranges for the Bondo, Kenya site and the alanine aminotransferase reference ranges for the Pretoria, South Africa site required adjustment. The phosphorus CRR passed verification and the creatinine CRR required adjustment at every site. The newly-established CRR intervals were narrower than the CRRs used previously at these study sites due to decreases in the upper limits of the reference ranges. As a result, more toxicities were detected. To ensure the safety of clinical trial participants, verification of CRRs should be standard practice in clinical trials conducted in settings where the CRR has not been validated for the local population. This verification method is simple, inexpensive, and can be performed by any medical laboratory.

  1. [Tobacco quality analysis of producing areas of Yunnan tobacco using near-infrared (NIR) spectrum].

    PubMed

    Wang, Yi; Ma, Xiang; Wen, Ya-Dong; Yu, Chun-Xia; Wang, Luo-Ping; Zhao, Long-Lian; Li, Jun-Hui

    2013-01-01

    In the present study, tobacco quality analysis of different producing areas was carried out applying spectrum projection and correlation methods. The group of industrial classification data was near-infrared (NIR) spectrum in 2010 year of middle parts of tobacco plant from Hongta Tobacco (Group) Co., Ltd. Twelve hundred seventy six superior tobacco leaf samples were collected from four producing areas, in which three areas from Yuxi, Chuxiong and Zhaotong, in Yunnan province all belong to tobacco varieties of K326 and one area from Dali belongs to tobacco varieties of Hongda. The conclusion showed that when the samples were divided into two parts by the ratio of 2 : 1 randomly as analysis and verification sets, the verification set corresponded with the analysis set applying spectrum projection because their correlation coefficients by the first and second dimensional projection were all above 0.99. At the same time, The study discussed a method to get the quantitative similarity values of different producing areas samples. The similarity values were instructive in tobacco plant planning, quality management, acquisition of raw materials of tobacco and tobacco leaf blending.

  2. Analytical verification and method comparison of the ADVIA Centaur® Intact Parathyroid Hormone assay.

    PubMed

    Fernández-Galán, Esther; Bedini, Josep Lluís; Filella, Xavier

    2017-12-01

    This study is the first verification of the novel iPTH Siemens ADVIA Centaur® Intact Parathyroid Hormone (iPTHm) chemiluminescence immunoassay based on monoclonal antibodies. We also compared the iPTH results obtained using this assay with the previous ADVIA Centaur® Parathyroid Hormone assay (iPTHp) based on polyclonal antibodies. The analytical performance study of iPTHm assay included LoD, LoQ, intra- and inter-assay reproducibility, and linearity. A comparison study was performed on 369 routine plasma samples. The results were analyzed independently for patients with normal and abnormal GFR, as well as patients on hemodialysis. In addition, clinical concordance between assays was assessed. Finally, we studied PTH stability of plasma samples at 4°C. For the iPTHm assay LoD and LoQ were 0.03pmol/L and 0.10pmol/L, respectively. Intra- and inter-assay CV were between 2.3% and 6.2%. Linearity was correct in the range from 3.82 to 203.08pmol/L. Correlation studies showed a good correlation (r=0.99) between iPTHm and iPTHp, with bias of -2.55% (IC -3.48% to -1.62%) in the range from 0.32 to 117.07pmol/L. Clinical concordance, assessed by Kappa Index, was 0.874. The stability study showed that differences compared to basal iPTH concentration did not exceed 20% in any of the samples analyzed. The iPTHm assay demonstrated acceptable performance and a very good clinical concordance with iPTHp assay, currently used in our laboratory. Thus, the novel iPTHm assay can replace the previous iPTHp assay, since results provided by both assays are very similar. In our study, the stability of iPTH is not affected by storage up to 14days. Copyright © 2017 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  3. Application of the precipitation-runoff modeling system to the Ah- shi-sle-pah Wash watershed, San Juan County, New Mexico

    USGS Publications Warehouse

    Hejl, H.R.

    1989-01-01

    The precipitation-runoff modeling system was applied to the 8.21 sq-mi drainage area of the Ah-shi-sle-pah Wash watershed in northwestern New Mexico. The calibration periods were May to September of 1981 and 1982, and the verification period was May to September 1983. Twelve storms were available for calibration and 8 storms were available for verification. For calibration A (hydraulic conductivity estimated from onsite data and other storm-mode parameters optimized), the computed standard error of estimate was 50% for runoff volumes and 72% of peak discharges. Calibration B included hydraulic conductivity in the optimization, which reduced the standard error of estimate to 28 % for runoff volumes and 50% for peak discharges. Optimized values for hydraulic conductivity resulted in reductions from 1.00 to 0.26 in/h and 0.20 to 0.03 in/h for the 2 general soils groups in the calibrations. Simulated runoff volumes using 7 of 8 storms occurring during the verification period had a standard error of estimate of 40% for verification A and 38% for verification B. Simulated peak discharge had a standard error of estimate of 120% for verification A and 56% for verification B. Including the eighth storm which had a relatively small magnitude in the verification analysis more than doubled the standard error of estimating volumes and peaks. (USGS)

  4. Experimental verification and simulation of negative index of refraction using Snell's law.

    PubMed

    Parazzoli, C G; Greegor, R B; Li, K; Koltenbah, B E C; Tanielian, M

    2003-03-14

    We report the results of a Snell's law experiment on a negative index of refraction material in free space from 12.6 to 13.2 GHz. Numerical simulations using Maxwell's equations solvers show good agreement with the experimental results, confirming the existence of negative index of refraction materials. The index of refraction is a function of frequency. At 12.6 GHz we measure and compute the real part of the index of refraction to be -1.05. The measurements and simulations of the electromagnetic field profiles were performed at distances of 14lambda and 28lambda from the sample; the fields were also computed at 100lambda.

  5. Verification of component mode techniques for flexible multibody systems

    NASA Technical Reports Server (NTRS)

    Wiens, Gloria J.

    1990-01-01

    Investigations were conducted in the modeling aspects of flexible multibodies undergoing large angular displacements. Models were to be generated and analyzed through application of computer simulation packages employing the 'component mode synthesis' techniques. Multibody Modeling, Verification and Control Laboratory (MMVC) plan was implemented, which includes running experimental tests on flexible multibody test articles. From these tests, data was to be collected for later correlation and verification of the theoretical results predicted by the modeling and simulation process.

  6. Using Concept Space to Verify Hyponymy in Building a Hyponymy Lexicon

    NASA Astrophysics Data System (ADS)

    Liu, Lei; Zhang, Sen; Diao, Lu Hong; Yan, Shu Ying; Cao, Cun Gen

    Verification of hyponymy relations is a basic problem in knowledge acquisition. We present a method of hyponymy verification based on concept space. Firstly, we give the definition of concept space about a group of candidate hyponymy relations. Secondly we analyze the concept space and define a set of hyponymy features based on the space structure. Then we use them to verify candidate hyponymy relations. Experimental results show that the method can provide adequate verification of hyponymy.

  7. High-Temperature Fluid-Wall Reactor Technology Research, Test and Evaluation Performed at Naval Construction Battalion Center, Gulfport, MS, for the USAF Installation/Restoration Program

    DTIC Science & Technology

    1988-01-01

    under field conditions. Sampling and analytical laboratory activities were performed by Ecology and Environment, Inc., and California Analytical...the proposed AER3 test conditions. All test samples would be obtained onsite by Ecology and Environment, Inc., of Buffalo, New York, and sent to...ensuring its safe operation. Ecology and Environment performed onsite verification sampling. This activity was coordinated with the Huber project team

  8. Transistor step stress testing program for JANTX2N2905A

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The effect of power/temperature step stress when applied to the transistor JANTX2N2905A manufactured by Texas Instruments and Motorola is reported. A total of 48 samples from each manufacturer was submitted to the process outlined. In addition, two control sample units were maintained for verification of the electrical parametric testing. All test samples were subjected to the electrical tests outlined in Table 2 after completing the prior power/temperature step stress point.

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bolme, David S; Tokola, Ryan A; Boehnen, Chris Bensing

    Automatic recognition systems are a valuable tool for identifying unknown deceased individuals. Immediately af- ter death fingerprint and face biometric samples are easy to collect using standard sensors and cameras and can be easily matched to anti-mortem biometric samples. Even though post-mortem fingerprints and faces have been used for decades, there are no studies that track these biomet- rics through the later stages of decomposition to determine the length of time the biometrics remain viable. This paper discusses a multimodal dataset of fingerprints, faces, and irises from 14 human cadavers that decomposed outdoors under natural conditions. Results include predictive modelsmore » relating time and temperature, measured as Accumulated Degree Days (ADD), and season (winter, spring, summer) to the predicted probably of automatic verification using a commercial algorithm.« less

  10. Chemical Analysis Results for Potable Water from ISS Expeditions 21 Through 25

    NASA Technical Reports Server (NTRS)

    Straub, John E., II; Plumlee, Debrah K.; Schultz, John R.; McCoy, J. Torin

    2011-01-01

    The Johnson Space Center Water and Food Analytical Laboratory (WAFAL) performed detailed ground-based analyses of archival water samples for verification of the chemical quality of the International Space Station (ISS) potable water supplies for Expeditions 21 through 25. Over a 14-month period the Space Shuttle visited the ISS on four occasions to complete construction and deliver supplies. The onboard supplies of potable water available for consumption by the Expeditions 21 to 25 crews consisted of Russian ground-supplied potable water, Russian potable water regenerated from humidity condensate, and US potable water recovered from urine distillate and condensate. Chemical archival water samples that were collected with U.S. hardware during Expeditions 21 to 25 were returned on Shuttle flights STS-129 (ULF3), STS-130 (20A), STS-131 (19A), and STS-132 (ULF4), as well as on Soyuz flights 19-23. This paper reports the analytical results for these returned potable water archival samples and their compliance with ISS water quality standards.

  11. Usage of CT data in biomechanical research

    NASA Astrophysics Data System (ADS)

    Safonov, Roman A.; Golyadkina, Anastasiya A.; Kirillova, Irina V.; Kossovich, Leonid Y.

    2017-02-01

    Object of study: The investigation is focused on development of personalized medicine. The determination of mechanical properties of bone tissues based on in vivo data was considered. Methods: CT, MRI, natural experiments on versatile test machine Instron 5944, numerical experiments using Python programs. Results: The medical diagnostics methods, which allows determination of mechanical properties of bone tissues based on in vivo data. The series of experiments to define the values of mechanical parameters of bone tissues. For one and the same sample, computed tomography (CT), magnetic resonance imaging (MRI), ultrasonic investigations and mechanical experiments on single-column test machine Instron 5944 were carried out. The computer program for comparison of CT and MRI images was created. The grayscale values in the same points of the samples were determined on both CT and MRI images. The Haunsfield grayscale values were used to determine rigidity (Young module) and tensile strength of the samples. The obtained data was compared to natural experiments results for verification.

  12. Identifying, Visualizing, and Fusing Social Media Data to Support Nonproliferation and Arms Control Treaty Verification: Preliminary Results

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gastelum, Zoe N.; Cramer, Nicholas O.; Benz, Jacob M.

    While international nonproliferation and arms control verification capabilities have their foundations in physical and chemical sensors, state declarations, and on-site inspections, verification experts are beginning to consider the importance of open source data to complement and support traditional means of verification. One of those new, and increasingly expanding, sources of open source information is social media, which can be ingested and understood through social media analytics (SMA). Pacific Northwest National Laboratory (PNNL) is conducting research to further our ability to identify, visualize, and fuse social media data to support nonproliferation and arms control treaty verification efforts. This paper will describemore » our preliminary research to examine social media signatures of nonproliferation or arms control proxy events. We will describe the development of our preliminary nonproliferation and arms control proxy events, outline our initial findings, and propose ideas for future work.« less

  13. Critical Surface Cleaning and Verification Alternatives

    NASA Technical Reports Server (NTRS)

    Melton, Donald M.; McCool, A. (Technical Monitor)

    2000-01-01

    As a result of federal and state requirements, historical critical cleaning and verification solvents such as Freon 113, Freon TMC, and Trichloroethylene (TCE) are either highly regulated or no longer 0 C available. Interim replacements such as HCFC 225 have been qualified, however toxicity and future phase-out regulations necessitate long term solutions. The scope of this project was to qualify a safe and environmentally compliant LOX surface verification alternative to Freon 113, TCE and HCFC 225. The main effort was focused on initiating the evaluation and qualification of HCFC 225G as an alternate LOX verification solvent. The project was scoped in FY 99/00 to perform LOX compatibility, cleaning efficiency and qualification on flight hardware.

  14. A digital flight control system verification laboratory

    NASA Technical Reports Server (NTRS)

    De Feo, P.; Saib, S.

    1982-01-01

    A NASA/FAA program has been established for the verification and validation of digital flight control systems (DFCS), with the primary objective being the development and analysis of automated verification tools. In order to enhance the capabilities, effectiveness, and ease of using the test environment, software verification tools can be applied. Tool design includes a static analyzer, an assertion generator, a symbolic executor, a dynamic analysis instrument, and an automated documentation generator. Static and dynamic tools are integrated with error detection capabilities, resulting in a facility which analyzes a representative testbed of DFCS software. Future investigations will ensue particularly in the areas of increase in the number of software test tools, and a cost effectiveness assessment.

  15. Goddard high resolution spectrograph science verification and data analysis

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The data analysis performed was to support the Orbital Verification (OV) and Science Verification (SV) of the GHRS was in the areas of the Digicon detector's performance and stability, wavelength calibration, and geomagnetic induced image motion. The results of the analyses are briefly described. Detailed results are given in the form of attachments. Specialized software was developed for the analyses. Calibration files were formatted according to the specifications in a Space Telescope Science report. IRAS images were restored of the Large Magellanic Cloud using a blocked iterative algorithm. The algorithm works with the raw data scans without regridding or interpolating the data on an equally spaced image grid.

  16. ED08-0053-07

    NASA Image and Video Library

    2008-02-28

    An ER-2 high-altitude Earth science aircraft banks away during a flight over the southern Sierra Nevada. NASA’s Armstrong Flight Research Center operates two of the Lockheed-built aircraft on a wide variety of environmental science, atmospheric sampling, and satellite data verification missions.

  17. Methods and Procedures in PIRLS 2016

    ERIC Educational Resources Information Center

    Martin, Michael O., Ed.; Mullis, Ina V. S., Ed.; Hooper, Martin, Ed.

    2017-01-01

    "Methods and Procedures in PIRLS 2016" documents the development of the Progress in International Reading Literacy Study (PIRLS) assessments and questionnaires and describes the methods used in sampling, translation verification, data collection, database construction, and the construction of the achievement and context questionnaire…

  18. Application of computer vision to automatic prescription verification in pharmaceutical mail order

    NASA Astrophysics Data System (ADS)

    Alouani, Ali T.

    2005-05-01

    In large volume pharmaceutical mail order, before shipping out prescriptions, licensed pharmacists ensure that the drug in the bottle matches the information provided in the patient prescription. Typically, the pharmacist has about 2 sec to complete the prescription verification process of one prescription. Performing about 1800 prescription verification per hour is tedious and can generate human errors as a result of visual and brain fatigue. Available automatic drug verification systems are limited to a single pill at a time. This is not suitable for large volume pharmaceutical mail order, where a prescription can have as many as 60 pills and where thousands of prescriptions are filled every day. In an attempt to reduce human fatigue, cost, and limit human error, the automatic prescription verification system (APVS) was invented to meet the need of large scale pharmaceutical mail order. This paper deals with the design and implementation of the first prototype online automatic prescription verification machine to perform the same task currently done by a pharmacist. The emphasis here is on the visual aspects of the machine. The system has been successfully tested on 43,000 prescriptions.

  19. Investigation of a Verification and Validation Tool with a Turbofan Aircraft Engine Application

    NASA Technical Reports Server (NTRS)

    Uth, Peter; Narang-Siddarth, Anshu; Wong, Edmond

    2018-01-01

    The development of more advanced control architectures for turbofan aircraft engines can yield gains in performance and efficiency over the lifetime of an engine. However, the implementation of these increasingly complex controllers is contingent on their ability to provide safe, reliable engine operation. Therefore, having the means to verify the safety of new control algorithms is crucial. As a step towards this goal, CoCoSim, a publicly available verification tool for Simulink, is used to analyze C-MAPSS40k, a 40,000 lbf class turbo-fan engine model developed at NASA for testing new control algorithms. Due to current limitations of the verification software, several modifications are made to C-MAPSS40k to achieve compatibility with CoCoSim. Some of these modifications sacrifice fidelity to the original model. Several safety and performance requirements typical for turbofan engines are identified and constructed into a verification framework. Preliminary results using an industry standard baseline controller for these requirements are presented. While verification capabilities are demonstrated, a truly comprehensive analysis will require further development of the verification tool.

  20. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, PERFORMANCE TEST RESULTS FOR THE A AND A ENVIRONMENTAL SEALS' SEAL ASSIST SYSTEM (SAS), PHASE I--TECHNOLOGY VERIFICATION REPORT

    EPA Science Inventory

    The report presents results of tests determining the efficacy of A&A Environmental Seals, Inc's Seal Assist System (SAS) in preventing natural gas compressor station's compressor rod packing leaks from escaping into the atmosphere. The SAS consists of an Emission Containment Glan...

  1. Performance evaluation of a chemiluminescence microparticle immunoassay for CK-MB.

    PubMed

    Lin, Zhi-Yuan; Fang, Yi-Zhen; Jin, Hong-Wei; Lin, Hua-Yue; Dai, Zhang; Luo, Qing; Li, Hong-Wei; Lin, Yan-Ling; Huang, Shui-Zhen; Gao, Lei; Xu, Fei-Hai; Zhang, Zhong-Ying

    2018-03-31

    To verify and evaluate the performance characteristics of a creatine kinase phosphokinase isoenzymes MB (CK-MB) assay kit, which produced by Xiamen Innodx Biotech Co. Ltd. Evaluation was carried out according to "Guidelines for principle of analysis performance evaluation of in vitro diagnostic reagent." The performance parameters included detection limit, linearity range, reportable range, recovery test, precision verification, interference test, cross-reactivity, matrix effect, and method comparison. The detection limit was 0.1 ng/mL. The assay had clinical linearity over range of 0.1 ng/mL-500 ng/mL. Reportable range was from 0.1 ng/mL to 1000 ng/mL. The average percent of recovery was 99.66%. The coefficient of variation (CV) for within-run and between-run of low CK-MB sample was 5.55% and 6.16%, respectively. As for high-level sample, it was 7.88% and 7.80%. In medical decision level, the relative deviation (Bias) of all interference tests was lower than 15%. When the sample had mild-hemolysis; hemoglobin ≤15 g/L; triglyceride ≤17 mmol/L; bilirubin ≤427.5 μmol/L; rheumatoid factor ≤206U/mL, there was no significant interference to be found. Moreover, assay kit had no cross-reaction with CK-MM and CK-BB. At last, total diagnostic accuracy of kit was 93.24%, when compared with refer kit. Overall the results of the verification study indicated the performance of kit is met the requirements of the clinical test. © 2018 Wiley Periodicals, Inc.

  2. Measuring Data Quality Through a Source Data Verification Audit in a Clinical Research Setting.

    PubMed

    Houston, Lauren; Probst, Yasmine; Humphries, Allison

    2015-01-01

    Health data has long been scrutinised in relation to data quality and integrity problems. Currently, no internationally accepted or "gold standard" method exists measuring data quality and error rates within datasets. We conducted a source data verification (SDV) audit on a prospective clinical trial dataset. An audit plan was applied to conduct 100% manual verification checks on a 10% random sample of participant files. A quality assurance rule was developed, whereby if >5% of data variables were incorrect a second 10% random sample would be extracted from the trial data set. Error was coded: correct, incorrect (valid or invalid), not recorded or not entered. Audit-1 had a total error of 33% and audit-2 36%. The physiological section was the only audit section to have <5% error. Data not recorded to case report forms had the greatest impact on error calculations. A significant association (p=0.00) was found between audit-1 and audit-2 and whether or not data was deemed correct or incorrect. Our study developed a straightforward method to perform a SDV audit. An audit rule was identified and error coding was implemented. Findings demonstrate that monitoring data quality by a SDV audit can identify data quality and integrity issues within clinical research settings allowing quality improvement to be made. The authors suggest this approach be implemented for future research.

  3. The validation & verification of an LC/MS method for the determination of total docosahexaenoic acid concentrations in canine blood serum.

    PubMed

    Dillon, Gerald Patrick; Keegan, Jason D; Wallace, Geoff; Yiannikouris, Alexandros; Moran, Colm Anthony

    2018-06-01

    Docosahexaenoic acid (DHA), is an omega 3 fatty acid (n-3 FA) that has been shown to play a role in canine growth and physiological integrity and improvements in skin and coat condition. However, potential adverse effects of n-3 FA specifically, impaired cellular immunity has been observed in dogs fed diets with elevated levels of n-3 FA. As such, a safe upper limit (SUL) for total n-3 FAs (DHA and EPA) in dogs has been established. Considering this SUL, sensitive methods detecting DHA in blood serum as a biomarker when conducting n-3 FA supplementation trials involving dogs are required. In this study, an LC-ESI-MS/MS method of DHA detection in dog serum was validated and verified. Recovery of DHA was optimized and parallelism tests were conducted with spiked samples demonstrating that the serum matrix did not interfere with quantitation. The stability of DHA in serum was also investigated, with -80 °C considered suitable when storing samples for up to six months. The method was linear over a calibration range of 1-500 μg/mL and precision and accuracy were found to meet the requirements for validation. This method was verified in an alternative laboratory using a different analytical system and operator, with the results meeting the criteria for verification. Copyright © 2018. Published by Elsevier Inc.

  4. Blood collection tubes as medical devices: The potential to affect assays and proposed verification and validation processes for the clinical laboratory.

    PubMed

    Bowen, Raffick A R; Adcock, Dorothy M

    2016-12-01

    Blood collection tubes (BCTs) are an often under-recognized variable in the preanalytical phase of clinical laboratory testing. Unfortunately, even the best-designed and manufactured BCTs may not work well in all clinical settings. Clinical laboratories, in collaboration with healthcare providers, should carefully evaluate BCTs prior to putting them into clinical use to determine their limitations and ensure that patients are not placed at risk because of inaccuracies due to poor tube performance. Selection of the best BCTs can be achieved through comparing advertising materials, reviewing the literature, observing the device at a scientific meeting, receiving a demonstration, evaluating the device under simulated conditions, or testing the device with patient samples. Although many publications have discussed method validations, few detail how to perform experiments for tube verification and validation. This article highlights the most common and impactful variables related to BCTs and discusses the validation studies that a typical clinical laboratory should perform when selecting BCTs. We also present a brief review of how in vitro diagnostic devices, particularly BCTs, are regulated in the United States, the European Union, and Canada. The verification and validation of BCTs will help to avoid the economic and human costs associated with incorrect test results, including poor patient care, unnecessary testing, and delays in test results. We urge laboratorians, tube manufacturers, diagnostic companies, and other researchers to take all the necessary steps to protect against the adverse effects of BCT components and their additives on clinical assays. Copyright © 2016 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  5. Verification of a VRF Heat Pump Computer Model in EnergyPlus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nigusse, Bereket; Raustad, Richard

    2013-06-15

    This paper provides verification results of the EnergyPlus variable refrigerant flow (VRF) heat pump computer model using manufacturer's performance data. The paper provides an overview of the VRF model, presents the verification methodology, and discusses the results. The verification provides quantitative comparison of full and part-load performance to manufacturer's data in cooling-only and heating-only modes of operation. The VRF heat pump computer model uses dual range bi-quadratic performance curves to represent capacity and Energy Input Ratio (EIR) as a function of indoor and outdoor air temperatures, and dual range quadratic performance curves as a function of part-load-ratio for modeling part-loadmore » performance. These performance curves are generated directly from manufacturer's published performance data. The verification compared the simulation output directly to manufacturer's performance data, and found that the dual range equation fit VRF heat pump computer model predicts the manufacturer's performance data very well over a wide range of indoor and outdoor temperatures and part-load conditions. The predicted capacity and electric power deviations are comparbale to equation-fit HVAC computer models commonly used for packaged and split unitary HVAC equipment.« less

  6. A Preliminary Experimental Examination of Worldview Verification, Perceived Racism, and Stress Reactivity in African Americans

    PubMed Central

    Lucas, Todd; Lumley, Mark A.; Flack, John M.; Wegner, Rhiana; Pierce, Jennifer; Goetz, Stefan

    2016-01-01

    Objective According to worldview verification theory, inconsistencies between lived experiences and worldviews are psychologically threatening. These inconsistencies may be key determinants of stress processes that influence cardiovascular health disparities. This preliminary examination considers how experiencing injustice can affect perceived racism and biological stress reactivity among African Americans. Guided by worldview verification theory, it was hypothesized that responses to receiving an unfair outcome would be moderated by fairness of the accompanying decision process, and that this effect would further depend on the consistency of the decision process with preexisting justice beliefs. Method A sample of 118 healthy African American adults completed baseline measures of justice beliefs, followed by a laboratory-based social-evaluative stressor task. Two randomized fairness manipulations were implemented during the task: participants were given either high or low levels of distributive (outcome) and procedural (decision process) justice. Glucocorticoid (cortisol) and inflammatory (C-reactive protein) biological responses were measured in oral fluids, and attributions of racism were also measured. Results The hypothesized 3-way interaction was generally obtained. Among African Americans with a strong belief in justice, perceived racism, cortisol and C-reactive protein responses to low distributive justice were higher when procedural justice was low. Among African Americans with a weak belief in justice however, these responses were higher when a low level of distributive justice was coupled with high procedural justice. Conclusions Biological and psychological processes that contribute to cardiovascular health disparities are affected by consistency between individual-level and contextual justice factors. PMID:27018728

  7. Verification of Abbott 25-OH-vitamin D assay on the architect system.

    PubMed

    Hutchinson, Katrina; Healy, Martin; Crowley, Vivion; Louw, Michael; Rochev, Yury

    2017-04-01

    Analytical and clinical verification of both old and new generations of the Abbott total 25-hydroxyvitamin D (25OHD) assays, and an examination of reference Intervals. Determination of between-run precision, and Deming comparison between patient sample results for 25OHD on the Abbott Architect, DiaSorin Liaison and AB SCIEX API 4000 (LC-MS/MS). Establishment of uncertainty of measurement for 25OHD Architect methods using old and new generations of the reagents, and estimation of reference interval in healthy Irish population. For between-run precision the manufacturer claims 2.8% coefficients of variation (CVs) of 2.8% and 4.6% for their high and low controls, respectively. Our instrument showed CVs between 4% and 6.2% for all levels of the controls on both generations of the Abbott reagents. The between-run uncertainties were 0.28 and 0.36, with expanded uncertainties 0.87 and 0.98 for the old and the new generations of reagent, respectively. The difference between all methods used for patients' samples was within total allowable error, and the instruments produced clinically equivalent results. The results covered the medical decision points of 30, 40, 50 and 125 nmol/L. The reference interval for total 25OHD in our healthy Irish subjects was lower than recommended levels (24-111 nmol/L). In a clinical laboratory Abbott 25OHD immunoassays are a useful, rapid and accurate method for measuring total 25OHD. The new generation of the assay was confirmed to be reliable, accurate, and a good indicator for 25OHD measurement. More study is needed to establish reference intervals that correctly represent the healthy population in Ireland.

  8. EURATOM safeguards efforts in the development of spent fuel verification methods by non-destructive assay

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Matloch, L.; Vaccaro, S.; Couland, M.

    The back end of the nuclear fuel cycle continues to develop. The European Commission, particularly the Nuclear Safeguards Directorate of the Directorate General for Energy, implements Euratom safeguards and needs to adapt to this situation. The verification methods for spent nuclear fuel, which EURATOM inspectors can use, require continuous improvement. Whereas the Euratom on-site laboratories provide accurate verification results for fuel undergoing reprocessing, the situation is different for spent fuel which is destined for final storage. In particular, new needs arise from the increasing number of cask loadings for interim dry storage and the advanced plans for the construction ofmore » encapsulation plants and geological repositories. Various scenarios present verification challenges. In this context, EURATOM Safeguards, often in cooperation with other stakeholders, is committed to further improvement of NDA methods for spent fuel verification. In this effort EURATOM plays various roles, ranging from definition of inspection needs to direct participation in development of measurement systems, including support of research in the framework of international agreements and via the EC Support Program to the IAEA. This paper presents recent progress in selected NDA methods. These methods have been conceived to satisfy different spent fuel verification needs, ranging from attribute testing to pin-level partial defect verification. (authors)« less

  9. Environmental Technology Verification Report: Taconic Energy, Inc. TEA Fuel Additive

    EPA Science Inventory

    The Greenhouse Gas Technology Center (GHG Center) is one of six verification organizations operating under EPA’s ETV program. One sector of significant interest to GHG Center stakeholders is transportation - particularly technologies that result in fuel economy improvements. Taco...

  10. Advanced Curation Protocols for Mars Returned Sample Handling

    NASA Astrophysics Data System (ADS)

    Bell, M.; Mickelson, E.; Lindstrom, D.; Allton, J.

    Introduction: Johnson Space Center has over 30 years experience handling precious samples which include Lunar rocks and Antarctic meteorites. However, we recognize that future curation of samples from such missions as Genesis, Stardust, and Mars S mple Return, will require a high degree of biosafety combined witha extremely low levels of inorganic, organic, and biological contamination. To satisfy these requirements, research in the JSC Advanced Curation Lab is currently focused toward two major areas: preliminary examination techniques and cleaning and verification techniques . Preliminary Examination Techniques : In order to minimize the number of paths for contamination we are exploring the synergy between human &robotic sample handling in a controlled environment to help determine the limits of clean curation. Within the Advanced Curation Laboratory is a prototype, next-generation glovebox, which contains a robotic micromanipulator. The remotely operated manipulator has six degrees-of- freedom and can be programmed to perform repetitive sample handling tasks. Protocols are being tested and developed to perform curation tasks such as rock splitting, weighing, imaging, and storing. Techniques for sample transfer enabling more detailed remote examination without compromising the integrity of sample science are also being developed . The glovebox is equipped with a rapid transfer port through which samples can be passed without exposure. The transfer is accomplished by using a unique seal and engagement system which allows passage between containers while maintaining a first seal to the outside environment and a second seal to prevent the outside of the container cover and port door from becoming contaminated by the material being transferred. Cleaning and Verification Techniques: As part of the contamination control effort, innovative cleaning techniques are being identified and evaluated in conjunction with sensitive cleanliness verification methods. Towards this end, cleaning techniques such as ultrasonication in ultra -pure water (UPW), oxygen (O2) plasma, and carbon dioxide (CO2) "snow" are being used to clean a variety of different contaminants on a variety of different surfaces. Additionally, once cleaned, techniques to directly verify the s rface cleanliness are being developed. Theseu include X ray photoelectron spectroscopy (XPS) quantification, and screening with- contact angle measure ments , which can be correlated with XPS standards. Methods developed in the Advanced Curation Laboratory will determine the extent to which inorganic and biological contamination can be controlled and minimized.

  11. Verification of Space Weather Forecasts using Terrestrial Weather Approaches

    NASA Astrophysics Data System (ADS)

    Henley, E.; Murray, S.; Pope, E.; Stephenson, D.; Sharpe, M.; Bingham, S.; Jackson, D.

    2015-12-01

    The Met Office Space Weather Operations Centre (MOSWOC) provides a range of 24/7 operational space weather forecasts, alerts, and warnings, which provide valuable information on space weather that can degrade electricity grids, radio communications, and satellite electronics. Forecasts issued include arrival times of coronal mass ejections (CMEs), and probabilistic forecasts for flares, geomagnetic storm indices, and energetic particle fluxes and fluences. These forecasts are produced twice daily using a combination of output from models such as Enlil, near-real-time observations, and forecaster experience. Verification of forecasts is crucial for users, researchers, and forecasters to understand the strengths and limitations of forecasters, and to assess forecaster added value. To this end, the Met Office (in collaboration with Exeter University) has been adapting verification techniques from terrestrial weather, and has been working closely with the International Space Environment Service (ISES) to standardise verification procedures. We will present the results of part of this work, analysing forecast and observed CME arrival times, assessing skill using 2x2 contingency tables. These MOSWOC forecasts can be objectively compared to those produced by the NASA Community Coordinated Modelling Center - a useful benchmark. This approach cannot be taken for the other forecasts, as they are probabilistic and categorical (e.g., geomagnetic storm forecasts give probabilities of exceeding levels from minor to extreme). We will present appropriate verification techniques being developed to address these forecasts, such as rank probability skill score, and comparing forecasts against climatology and persistence benchmarks. As part of this, we will outline the use of discrete time Markov chains to assess and improve the performance of our geomagnetic storm forecasts. We will also discuss work to adapt a terrestrial verification visualisation system to space weather, to help MOSWOC forecasters view verification results in near real-time; plans to objectively assess flare forecasts under the EU Horizon 2020 FLARECAST project; and summarise ISES efforts to achieve consensus on verification.

  12. Exomars Mission Verification Approach

    NASA Astrophysics Data System (ADS)

    Cassi, Carlo; Gilardi, Franco; Bethge, Boris

    According to the long-term cooperation plan established by ESA and NASA in June 2009, the ExoMars project now consists of two missions: A first mission will be launched in 2016 under ESA lead, with the objectives to demonstrate the European capability to safely land a surface package on Mars, to perform Mars Atmosphere investigation, and to provide communi-cation capability for present and future ESA/NASA missions. For this mission ESA provides a spacecraft-composite, made up of an "Entry Descent & Landing Demonstrator Module (EDM)" and a Mars Orbiter Module (OM), NASA provides the Launch Vehicle and the scientific in-struments located on the Orbiter for Mars atmosphere characterisation. A second mission with it launch foreseen in 2018 is lead by NASA, who provides spacecraft and launcher, the EDL system, and a rover. ESA contributes the ExoMars Rover Module (RM) to provide surface mobility. It includes a drill system allowing drilling down to 2 meter, collecting samples and to investigate them for signs of past and present life with exobiological experiments, and to investigate the Mars water/geochemical environment, In this scenario Thales Alenia Space Italia as ESA Prime industrial contractor is in charge of the design, manufacturing, integration and verification of the ESA ExoMars modules, i.e.: the Spacecraft Composite (OM + EDM) for the 2016 mission, the RM for the 2018 mission and the Rover Operations Control Centre, which will be located at Altec-Turin (Italy). The verification process of the above products is quite complex and will include some pecu-liarities with limited or no heritage in Europe. Furthermore the verification approach has to be optimised to allow full verification despite significant schedule and budget constraints. The paper presents the verification philosophy tailored for the ExoMars mission in line with the above considerations, starting from the model philosophy, showing the verification activities flow and the sharing of tests between the different levels (system, modules, subsystems, etc) and giving an overview of the main test defined at Spacecraft level. The paper is mainly focused on the verification aspects of the EDL Demonstrator Module and the Rover Module, for which an intense testing activity without previous heritage in Europe is foreseen. In particular the Descent Module has to survive to the Mars atmospheric entry and landing, its surface platform has to stay operational for 8 sols on Martian surface, transmitting scientific data to the Orbiter. The Rover Module has to perform 180 sols mission in Mars surface environment. These operative conditions cannot be verified only by analysis; consequently a test campaign is defined including mechanical tests to simulate the entry loads, thermal test in Mars environment and the simulation of Rover operations on a 'Mars like' terrain. Finally, the paper present an overview of the documentation flow defined to ensure the correct translation of the mission requirements in verification activities (test, analysis, review of design) until the final verification close-out of the above requirements with the final verification reports.

  13. MAGIC polymer gel for dosimetric verification in boron neutron capture therapy

    PubMed Central

    Heikkinen, Sami; Kotiluoto, Petri; Serén, Tom; Seppälä, Tiina; Auterinen, Iiro; Savolainen, Sauli

    2007-01-01

    Radiation‐sensitive polymer gels are among the most promising three‐dimensional dose verification tools developed to date. We tested the normoxic polymer gel dosimeter known by the acronym MAGIC (methacrylic and ascorbic acid in gelatin initiated by copper) to evaluate its use in boron neutron capture therapy (BNCT) dosimetry. We irradiated a large cylindrical gel phantom (diameter: 10 cm; length: 20 cm) in the epithermal neutron beam of the Finnish BNCT facility at the FiR 1 nuclear reactor. Neutron irradiation was simulated with a Monte Carlo radiation transport code MCNP. To compare dose–response, gel samples from the same production batch were also irradiated with 6 MV photons from a medical linear accelerator. Irradiated gel phantoms then underwent magnetic resonance imaging to determine their R2 relaxation rate maps. The measured and normalized dose distribution in the epithermal neutron beam was compared with the dose distribution calculated by computer simulation. The results support the feasibility of using MAGIC gel in BNCT dosimetry. PACS numbers: 87.53.Qc, 87.53.Wz, 87.66.Ff PMID:17592463

  14. Verification of Electromagnetic Physics Models for Parallel Computing Architectures in the GeantV Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Amadio, G.; et al.

    An intensive R&D and programming effort is required to accomplish new challenges posed by future experimental high-energy particle physics (HEP) programs. The GeantV project aims to narrow the gap between the performance of the existing HEP detector simulation software and the ideal performance achievable, exploiting latest advances in computing technology. The project has developed a particle detector simulation prototype capable of transporting in parallel particles in complex geometries exploiting instruction level microparallelism (SIMD and SIMT), task-level parallelism (multithreading) and high-level parallelism (MPI), leveraging both the multi-core and the many-core opportunities. We present preliminary verification results concerning the electromagnetic (EM) physicsmore » models developed for parallel computing architectures within the GeantV project. In order to exploit the potential of vectorization and accelerators and to make the physics model effectively parallelizable, advanced sampling techniques have been implemented and tested. In this paper we introduce a set of automated statistical tests in order to verify the vectorized models by checking their consistency with the corresponding Geant4 models and to validate them against experimental data.« less

  15. [Development of a microenvironment test chamber for airborne microbe research].

    PubMed

    Zhan, Ningbo; Chen, Feng; Du, Yaohua; Cheng, Zhi; Li, Chenyu; Wu, Jinlong; Wu, Taihu

    2017-10-01

    One of the most important environmental cleanliness indicators is airborne microbe. However, the particularity of clean operating environment and controlled experimental environment often leads to the limitation of the airborne microbe research. This paper designed and implemented a microenvironment test chamber for airborne microbe research in normal test conditions. Numerical simulation by Fluent showed that airborne microbes were evenly dispersed in the upper part of test chamber, and had a bottom-up concentration growth distribution. According to the simulation results, the verification experiment was carried out by selecting 5 sampling points in different space positions in the test chamber. Experimental results showed that average particle concentrations of all sampling points reached 10 7 counts/m 3 after 5 minutes' distributing of Staphylococcus aureus , and all sampling points showed the accordant mapping of concentration distribution. The concentration of airborne microbe in the upper chamber was slightly higher than that in the middle chamber, and that was also slightly higher than that in the bottom chamber. It is consistent with the results of numerical simulation, and it proves that the system can be well used for airborne microbe research.

  16. DFM flow by using combination between design based metrology system and model based verification at sub-50nm memory device

    NASA Astrophysics Data System (ADS)

    Kim, Cheol-kyun; Kim, Jungchan; Choi, Jaeseung; Yang, Hyunjo; Yim, Donggyu; Kim, Jinwoong

    2007-03-01

    As the minimum transistor length is getting smaller, the variation and uniformity of transistor length seriously effect device performance. So, the importance of optical proximity effects correction (OPC) and resolution enhancement technology (RET) cannot be overemphasized. However, OPC process is regarded by some as a necessary evil in device performance. In fact, every group which includes process and design, are interested in whole chip CD variation trend and CD uniformity, which represent real wafer. Recently, design based metrology systems are capable of detecting difference between data base to wafer SEM image. Design based metrology systems are able to extract information of whole chip CD variation. According to the results, OPC abnormality was identified and design feedback items are also disclosed. The other approaches are accomplished on EDA companies, like model based OPC verifications. Model based verification will be done for full chip area by using well-calibrated model. The object of model based verification is the prediction of potential weak point on wafer and fast feed back to OPC and design before reticle fabrication. In order to achieve robust design and sufficient device margin, appropriate combination between design based metrology system and model based verification tools is very important. Therefore, we evaluated design based metrology system and matched model based verification system for optimum combination between two systems. In our study, huge amount of data from wafer results are classified and analyzed by statistical method and classified by OPC feedback and design feedback items. Additionally, novel DFM flow would be proposed by using combination of design based metrology and model based verification tools.

  17. Authoring and verification of clinical guidelines: a model driven approach.

    PubMed

    Pérez, Beatriz; Porres, Ivan

    2010-08-01

    The goal of this research is to provide a framework to enable authoring and verification of clinical guidelines. The framework is part of a larger research project aimed at improving the representation, quality and application of clinical guidelines in daily clinical practice. The verification process of a guideline is based on (1) model checking techniques to verify guidelines against semantic errors and inconsistencies in their definition, (2) combined with Model Driven Development (MDD) techniques, which enable us to automatically process manually created guideline specifications and temporal-logic statements to be checked and verified regarding these specifications, making the verification process faster and cost-effective. Particularly, we use UML statecharts to represent the dynamics of guidelines and, based on this manually defined guideline specifications, we use a MDD-based tool chain to automatically process them to generate the input model of a model checker. The model checker takes the resulted model together with the specific guideline requirements, and verifies whether the guideline fulfils such properties. The overall framework has been implemented as an Eclipse plug-in named GBDSSGenerator which, particularly, starting from the UML statechart representing a guideline, allows the verification of the guideline against specific requirements. Additionally, we have established a pattern-based approach for defining commonly occurring types of requirements in guidelines. We have successfully validated our overall approach by verifying properties in different clinical guidelines resulting in the detection of some inconsistencies in their definition. The proposed framework allows (1) the authoring and (2) the verification of clinical guidelines against specific requirements defined based on a set of property specification patterns, enabling non-experts to easily write formal specifications and thus easing the verification process. Copyright 2010 Elsevier Inc. All rights reserved.

  18. A multispectral photon-counting double random phase encoding scheme for image authentication.

    PubMed

    Yi, Faliu; Moon, Inkyu; Lee, Yeon H

    2014-05-20

    In this paper, we propose a new method for color image-based authentication that combines multispectral photon-counting imaging (MPCI) and double random phase encoding (DRPE) schemes. The sparsely distributed information from MPCI and the stationary white noise signal from DRPE make intruder attacks difficult. In this authentication method, the original multispectral RGB color image is down-sampled into a Bayer image. The three types of color samples (red, green and blue color) in the Bayer image are encrypted with DRPE and the amplitude part of the resulting image is photon counted. The corresponding phase information that has nonzero amplitude after photon counting is then kept for decryption. Experimental results show that the retrieved images from the proposed method do not visually resemble their original counterparts. Nevertheless, the original color image can be efficiently verified with statistical nonlinear correlations. Our experimental results also show that different interpolation algorithms applied to Bayer images result in different verification effects for multispectral RGB color images.

  19. Urine sampling and collection system optimization and testing

    NASA Technical Reports Server (NTRS)

    Fogal, G. L.; Geating, J. A.; Koesterer, M. G.

    1975-01-01

    A Urine Sampling and Collection System (USCS) engineering model was developed to provide for the automatic collection, volume sensing and sampling of urine from each micturition. The purpose of the engineering model was to demonstrate verification of the system concept. The objective of the optimization and testing program was to update the engineering model, to provide additional performance features and to conduct system testing to determine operational problems. Optimization tasks were defined as modifications to minimize system fluid residual and addition of thermoelectric cooling.

  20. Ares I-X Range Safety Simulation Verification and Analysis Independent Validation and Verification

    NASA Technical Reports Server (NTRS)

    Merry, Carl M.; Tarpley, Ashley F.; Craig, A. Scott; Tartabini, Paul V.; Brewer, Joan D.; Davis, Jerel G.; Dulski, Matthew B.; Gimenez, Adrian; Barron, M. Kyle

    2011-01-01

    NASA s Ares I-X vehicle launched on a suborbital test flight from the Eastern Range in Florida on October 28, 2009. To obtain approval for launch, a range safety final flight data package was generated to meet the data requirements defined in the Air Force Space Command Manual 91-710 Volume 2. The delivery included products such as a nominal trajectory, trajectory envelopes, stage disposal data and footprints, and a malfunction turn analysis. The Air Force s 45th Space Wing uses these products to ensure public and launch area safety. Due to the criticality of these data, an independent validation and verification effort was undertaken to ensure data quality and adherence to requirements. As a result, the product package was delivered with the confidence that independent organizations using separate simulation software generated data to meet the range requirements and yielded consistent results. This document captures Ares I-X final flight data package verification and validation analysis, including the methodology used to validate and verify simulation inputs, execution, and results and presents lessons learned during the process

  1. AN ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) TESTING OF FOUR MERCURY EMISSION SAMPLING SYSTEMS

    EPA Science Inventory

    CEMs - Tekran Instrument Corp. Series 3300 and Thermo Electron's Mercury Freedom System Continuous Emission Monitors (CEMs) for mercury are designed to determine total and/or chemically speciated vapor-phase mercury in combustion emissions. Performance for mercury CEMs are cont...

  2. FIELD VERIFICATION OF LINERS FROM SANITARY LANDFILLS

    EPA Science Inventory

    Liner specimens from three existing landfill sites were collected and examined to determine the changes in their physical properties over time and to validate data being developed through laboratory research. Samples examined included a 15-mil PVC liner from a sludge lagoon in Ne...

  3. Some Methods for Evaluating Program Implementation.

    ERIC Educational Resources Information Center

    Hardy, Roy A.

    An approach to evaluating program implementation is described. This approach includes the development of a project description which includes a structure matrix, sampling from the structure matrix, and preparing an implementation evaluation plan. The implementation evaluation plan should include: (1) verification of implementation of planned…

  4. Multi-level slug tests in highly permeable formations: 2. Hydraulic conductivity identification, method verification, and field applications

    USGS Publications Warehouse

    Zlotnik, V.A.; McGuire, V.L.

    1998-01-01

    Using the developed theory and modified Springer-Gelhar (SG) model, an identification method is proposed for estimating hydraulic conductivity from multi-level slug tests. The computerized algorithm calculates hydraulic conductivity from both monotonic and oscillatory well responses obtained using a double-packer system. Field verification of the method was performed at a specially designed fully penetrating well of 0.1-m diameter with a 10-m screen in a sand and gravel alluvial aquifer (MSEA site, Shelton, Nebraska). During well installation, disturbed core samples were collected every 0.6 m using a split-spoon sampler. Vertical profiles of hydraulic conductivity were produced on the basis of grain-size analysis of the disturbed core samples. These results closely correlate with the vertical profile of horizontal hydraulic conductivity obtained by interpreting multi-level slug test responses using the modified SG model. The identification method was applied to interpret the response from 474 slug tests in 156 locations at the MSEA site. More than 60% of responses were oscillatory. The method produced a good match to experimental data for both oscillatory and monotonic responses using an automated curve matching procedure. The proposed method allowed us to drastically increase the efficiency of each well used for aquifer characterization and to process massive arrays of field data. Recommendations generalizing this experience to massive application of the proposed method are developed.Using the developed theory and modified Springer-Gelhar (SG) model, an identification method is proposed for estimating hydraulic conductivity from multi-level slug tests. The computerized algorithm calculates hydraulic conductivity from both monotonic and oscillatory well responses obtained using a double-packer system. Field verification of the method was performed at a specially designed fully penetrating well of 0.1-m diameter with a 10-m screen in a sand and gravel alluvial aquifer (MSEA site, Shelton, Nebraska). During well installation, disturbed core samples were collected every 0.6 m using a split-spoon sampler. Vertical profiles of hydraulic conductivity were produced on the basis of grain-size analysis of the disturbed core samples. These results closely correlate with the vertical profile of horizontal hydraulic conductivity obtained by interpreting multi-level slug test responses using the modified SG model. The identification method was applied to interpret the response from 474 slug tests in 156 locations at the MSEA site. More than 60% of responses were oscillatory. The method produced a good match to experimental data for both oscillatory and monotonic responses using an automated curve matching procedure. The proposed method allowed us to drastically increase the efficiency of each well used for aquifer characterization and to process massive arrays of field data. Recommendations generalizing this experience to massive application of the proposed method are developed.

  5. 49 CFR 40.327 - When must the MRO report medical information gathered in the verification process?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... results and medical information you learned as part of the verification process to third parties without... the course of an accident investigation. (c) If the law of a foreign country (e.g., Canada) prohibits...

  6. Experimental evaluation of fingerprint verification system based on double random phase encoding

    NASA Astrophysics Data System (ADS)

    Suzuki, Hiroyuki; Yamaguchi, Masahiro; Yachida, Masuyoshi; Ohyama, Nagaaki; Tashima, Hideaki; Obi, Takashi

    2006-03-01

    We proposed a smart card holder authentication system that combines fingerprint verification with PIN verification by applying a double random phase encoding scheme. In this system, the probability of accurate verification of an authorized individual reduces when the fingerprint is shifted significantly. In this paper, a review of the proposed system is presented and preprocessing for improving the false rejection rate is proposed. In the proposed method, the position difference between two fingerprint images is estimated by using an optimized template for core detection. When the estimated difference exceeds the permissible level, the user inputs the fingerprint again. The effectiveness of the proposed method is confirmed by a computational experiment; its results show that the false rejection rate is improved.

  7. PFLOTRAN Verification: Development of a Testing Suite to Ensure Software Quality

    NASA Astrophysics Data System (ADS)

    Hammond, G. E.; Frederick, J. M.

    2016-12-01

    In scientific computing, code verification ensures the reliability and numerical accuracy of a model simulation by comparing the simulation results to experimental data or known analytical solutions. The model is typically defined by a set of partial differential equations with initial and boundary conditions, and verification ensures whether the mathematical model is solved correctly by the software. Code verification is especially important if the software is used to model high-consequence systems which cannot be physically tested in a fully representative environment [Oberkampf and Trucano (2007)]. Justified confidence in a particular computational tool requires clarity in the exercised physics and transparency in its verification process with proper documentation. We present a quality assurance (QA) testing suite developed by Sandia National Laboratories that performs code verification for PFLOTRAN, an open source, massively-parallel subsurface simulator. PFLOTRAN solves systems of generally nonlinear partial differential equations describing multiphase, multicomponent and multiscale reactive flow and transport processes in porous media. PFLOTRAN's QA test suite compares the numerical solutions of benchmark problems in heat and mass transport against known, closed-form, analytical solutions, including documentation of the exercised physical process models implemented in each PFLOTRAN benchmark simulation. The QA test suite development strives to follow the recommendations given by Oberkampf and Trucano (2007), which describes four essential elements in high-quality verification benchmark construction: (1) conceptual description, (2) mathematical description, (3) accuracy assessment, and (4) additional documentation and user information. Several QA tests within the suite will be presented, including details of the benchmark problems and their closed-form analytical solutions, implementation of benchmark problems in PFLOTRAN simulations, and the criteria used to assess PFLOTRAN's performance in the code verification procedure. References Oberkampf, W. L., and T. G. Trucano (2007), Verification and Validation Benchmarks, SAND2007-0853, 67 pgs., Sandia National Laboratories, Albuquerque, NM.

  8. Influenza forecasting with Google Flu Trends.

    PubMed

    Dugas, Andrea Freyer; Jalalpour, Mehdi; Gel, Yulia; Levin, Scott; Torcaso, Fred; Igusa, Takeru; Rothman, Richard E

    2013-01-01

    We developed a practical influenza forecast model based on real-time, geographically focused, and easy to access data, designed to provide individual medical centers with advanced warning of the expected number of influenza cases, thus allowing for sufficient time to implement interventions. Secondly, we evaluated the effects of incorporating a real-time influenza surveillance system, Google Flu Trends, and meteorological and temporal information on forecast accuracy. Forecast models designed to predict one week in advance were developed from weekly counts of confirmed influenza cases over seven seasons (2004-2011) divided into seven training and out-of-sample verification sets. Forecasting procedures using classical Box-Jenkins, generalized linear models (GLM), and generalized linear autoregressive moving average (GARMA) methods were employed to develop the final model and assess the relative contribution of external variables such as, Google Flu Trends, meteorological data, and temporal information. A GARMA(3,0) forecast model with Negative Binomial distribution integrating Google Flu Trends information provided the most accurate influenza case predictions. The model, on the average, predicts weekly influenza cases during 7 out-of-sample outbreaks within 7 cases for 83% of estimates. Google Flu Trend data was the only source of external information to provide statistically significant forecast improvements over the base model in four of the seven out-of-sample verification sets. Overall, the p-value of adding this external information to the model is 0.0005. The other exogenous variables did not yield a statistically significant improvement in any of the verification sets. Integer-valued autoregression of influenza cases provides a strong base forecast model, which is enhanced by the addition of Google Flu Trends confirming the predictive capabilities of search query based syndromic surveillance. This accessible and flexible forecast model can be used by individual medical centers to provide advanced warning of future influenza cases.

  9. Nontargeted metabolomic analysis and "commercial-homophyletic" comparison-induced biomarkers verification for the systematic chemical differentiation of five different parts of Panax ginseng.

    PubMed

    Qiu, Shi; Yang, Wen-Zhi; Yao, Chang-Liang; Qiu, Zhi-Dong; Shi, Xiao-Jian; Zhang, Jing-Xian; Hou, Jin-Jun; Wang, Qiu-Rong; Wu, Wan-Ying; Guo, De-An

    2016-07-01

    A key segment in authentication of herbal medicines is the establishment of robust biomarkers that embody the intrinsic metabolites difference independent of the growing environment or processing technics. We present a strategy by nontargeted metabolomics and "Commercial-homophyletic" comparison-induced biomarkers verification with new bioinformatic vehicles, to improve the efficiency and reliability in authentication of herbal medicines. The chemical differentiation of five different parts (root, leaf, flower bud, berry, and seed) of Panax ginseng was illustrated as a case study. First, an optimized ultra-performance liquid chromatography/quadrupole time-of-flight-MS(E) (UPLC/QTOF-MS(E)) approach was established for global metabolites profiling. Second, UNIFI™ combined with search of an in-house library was employed to automatically characterize the metabolites. Third, pattern recognition multivariate statistical analysis of the MS(E) data of different parts of commercial and homophyletic samples were separately performed to explore potential biomarkers. Fourth, potential biomarkers deduced from commercial and homophyletic root and leaf samples were cross-compared to infer robust biomarkers. Fifth, discriminating models by artificial neutral network (ANN) were established to identify different parts of P. ginseng. Consequently, 164 compounds were characterized, and 11 robust biomarkers enabling the differentiation among root, leaf, flower bud, and berry, were discovered by removing those structurally unstable and possibly processing-related ones. The ANN models using the robust biomarkers managed to exactly discriminate four different parts and root adulterant with leaf as well. Conclusively, biomarkers verification using homophyletic samples conduces to the discovery of robust biomarkers. The integrated strategy facilitates authentication of herbal medicines in a more efficient and more intelligent manner. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. [Validation and verfication of microbiology methods].

    PubMed

    Camaró-Sala, María Luisa; Martínez-García, Rosana; Olmos-Martínez, Piedad; Catalá-Cuenca, Vicente; Ocete-Mochón, María Dolores; Gimeno-Cardona, Concepción

    2015-01-01

    Clinical microbiologists should ensure, to the maximum level allowed by the scientific and technical development, the reliability of the results. This implies that, in addition to meeting the technical criteria to ensure their validity, they must be performed with a number of conditions that allows comparable results to be obtained, regardless of the laboratory that performs the test. In this sense, the use of recognized and accepted reference methodsis the most effective tool for these guarantees. The activities related to verification and validation of analytical methods has become very important, as there is continuous development, as well as updating techniques and increasingly complex analytical equipment, and an interest of professionals to ensure quality processes and results. The definitions of validation and verification are described, along with the different types of validation/verification, and the types of methods, and the level of validation necessary depending on the degree of standardization. The situations in which validation/verification is mandatory and/or recommended is discussed, including those particularly related to validation in Microbiology. It stresses the importance of promoting the use of reference strains as controls in Microbiology and the use of standard controls, as well as the importance of participation in External Quality Assessment programs to demonstrate technical competence. The emphasis is on how to calculate some of the parameters required for validation/verification, such as the accuracy and precision. The development of these concepts can be found in the microbiological process SEIMC number 48: «Validation and verification of microbiological methods» www.seimc.org/protocols/microbiology. Copyright © 2013 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  11. Verification Of The Defense Waste Processing Facility's (DWPF) Process Digestion Methods For The Sludge Batch 8 Qualification Sample

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Click, D. R.; Edwards, T. B.; Wiedenman, B. J.

    2013-03-18

    This report contains the results and comparison of data generated from inductively coupled plasma – atomic emission spectroscopy (ICP-AES) analysis of Aqua Regia (AR), Sodium Peroxide/Sodium Hydroxide Fusion Dissolution (PF) and Cold Chem (CC) method digestions and Cold Vapor Atomic Absorption analysis of Hg digestions from the DWPF Hg digestion method of Sludge Batch 8 (SB8) Sludge Receipt and Adjustment Tank (SRAT) Receipt and SB8 SRAT Product samples. The SB8 SRAT Receipt and SB8 SRAT Product samples were prepared in the SRNL Shielded Cells, and the SRAT Receipt material is representative of the sludge that constitutes the SB8 Batch ormore » qualification composition. This is the sludge in Tank 51 that is to be transferred into Tank 40, which will contain the heel of Sludge Batch 7b (SB7b), to form the SB8 Blend composition.« less

  12. Finite element simulation and experimental verification of ultrasonic non-destructive inspection of defects in additively manufactured materials

    NASA Astrophysics Data System (ADS)

    Taheri, H.; Koester, L.; Bigelow, T.; Bond, L. J.

    2018-04-01

    Industrial applications of additively manufactured components are increasing quickly. Adequate quality control of the parts is necessary in ensuring safety when using these materials. Base material properties, surface conditions, as well as location and size of defects are some of the main targets for nondestructive evaluation of additively manufactured parts, and the problem of adequate characterization is compounded given the challenges of complex part geometry. Numerical modeling can allow the interplay of the various factors to be studied, which can lead to improved measurement design. This paper presents a finite element simulation verified by experimental results of ultrasonic waves scattering from flat bottom holes (FBH) in additive manufacturing materials. A focused beam immersion ultrasound transducer was used for both the modeling and simulations in the additive manufactured samples. The samples were SS17 4 PH steel samples made by laser sintering in a powder bed.

  13. Real-Time Verification of a High-Dose-Rate Iridium 192 Source Position Using a Modified C-Arm Fluoroscope

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nose, Takayuki, E-mail: nose-takayuki@nms.ac.jp; Chatani, Masashi; Otani, Yuki

    Purpose: High-dose-rate (HDR) brachytherapy misdeliveries can occur at any institution, and they can cause disastrous results. Even a patient's death has been reported. Misdeliveries could be avoided with real-time verification methods. In 1996, we developed a modified C-arm fluoroscopic verification of an HDR Iridium 192 source position prevent these misdeliveries. This method provided excellent image quality sufficient to detect errors, and it has been in clinical use at our institutions for 20 years. The purpose of the current study is to introduce the mechanisms and validity of our straightforward C-arm fluoroscopic verification method. Methods and Materials: Conventional X-ray fluoroscopic images aremore » degraded by spurious signals and quantum noise from Iridium 192 photons, which make source verification impractical. To improve image quality, we quadrupled the C-arm fluoroscopic X-ray dose per pulse. The pulse rate was reduced by a factor of 4 to keep the average exposure compliant with Japanese medical regulations. The images were then displayed with quarter-frame rates. Results: Sufficient quality was obtained to enable observation of the source position relative to both the applicators and the anatomy. With this method, 2 errors were detected among 2031 treatment sessions for 370 patients within a 6-year period. Conclusions: With the use of a modified C-arm fluoroscopic verification method, treatment errors that were otherwise overlooked were detected in real time. This method should be given consideration for widespread use.« less

  14. Ontology Matching with Semantic Verification.

    PubMed

    Jean-Mary, Yves R; Shironoshita, E Patrick; Kabuka, Mansur R

    2009-09-01

    ASMOV (Automated Semantic Matching of Ontologies with Verification) is a novel algorithm that uses lexical and structural characteristics of two ontologies to iteratively calculate a similarity measure between them, derives an alignment, and then verifies it to ensure that it does not contain semantic inconsistencies. In this paper, we describe the ASMOV algorithm, and then present experimental results that measure its accuracy using the OAEI 2008 tests, and that evaluate its use with two different thesauri: WordNet, and the Unified Medical Language System (UMLS). These results show the increased accuracy obtained by combining lexical, structural and extensional matchers with semantic verification, and demonstrate the advantage of using a domain-specific thesaurus for the alignment of specialized ontologies.

  15. Weak-lensing mass calibration of redMaPPer galaxy clusters in Dark Energy Survey Science Verification data

    DOE PAGES

    Melchior, P.; Gruen, D.; McClintock, T.; ...

    2017-05-16

    Here, we use weak-lensing shear measurements to determine the mean mass of optically selected galaxy clusters in Dark Energy Survey Science Verification data. In a blinded analysis, we split the sample of more than 8000 redMaPPer clusters into 15 subsets, spanning ranges in the richness parameter 5 ≤ λ ≤ 180 and redshift 0.2 ≤ z ≤ 0.8, and fit the averaged mass density contrast profiles with a model that accounts for seven distinct sources of systematic uncertainty: shear measurement and photometric redshift errors; cluster-member contamination; miscentring; deviations from the NFW halo profile; halo triaxiality and line-of-sight projections.

  16. Weak-lensing mass calibration of redMaPPer galaxy clusters in Dark Energy Survey Science Verification data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Melchior, P.; Gruen, D.; McClintock, T.

    Here, we use weak-lensing shear measurements to determine the mean mass of optically selected galaxy clusters in Dark Energy Survey Science Verification data. In a blinded analysis, we split the sample of more than 8000 redMaPPer clusters into 15 subsets, spanning ranges in the richness parameter 5 ≤ λ ≤ 180 and redshift 0.2 ≤ z ≤ 0.8, and fit the averaged mass density contrast profiles with a model that accounts for seven distinct sources of systematic uncertainty: shear measurement and photometric redshift errors; cluster-member contamination; miscentring; deviations from the NFW halo profile; halo triaxiality and line-of-sight projections.

  17. Rapid diagnosis of common deletional α-thalassemia in the Chinese population by qPCR based on identical primer homologous fragments.

    PubMed

    Long, Ju

    2016-05-01

    In China, -(SEA), -α(3.7) and -α(4.2) are common deletional α-thalassemia alleles. Gap-PCR is the currently used detection method for these alleles, whose disadvantages include time-consuming procedure and increased potential for PCR product contamination. Therefore, this detection method needs to be improved. Based on identical-primer homologous fragments, a qPCR system was developed for deletional α-thalassemia genotyping, which was composed of a group of quantitatively-related primers and their corresponding probes plus two groups of qualitatively-related primers and their corresponding probes. In order to verify the accuracy of the qPCR system, known genotype samples and random samples are employed. The standard curve result demonstrated that designed primers and probes all yielded good amplification efficiency. In the tests of known genotype samples and random samples, sample detection results were consistent with verification results. In detecting αα, -(SEA), -α(3.7) and -α(4.2) alleles, deletional α-thalassemia alleles are accurately detected by this method. In addition, this method is provided with a wider detection range, greater speed and reduced PCR product contamination risk when compared with current common gap-PCR detection reagents. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Hayabusa: Navigation Challenges for Earth Return

    NASA Technical Reports Server (NTRS)

    Haw, Robert J.; Bhaskaran, S.; Strauss, W.; Sklyanskiy, E.; Graat, E. J.; Smith, J. J.; Menom, P.; Ardalan, S.; Ballard, C.; Williams, P.; hide

    2011-01-01

    Hayabusa was a JAXA sample-return mission to Itokawa navigated, in part, by JPL personnel. Hayabusa survived several near mission-ending failures at Itokawa yet returned to Earth with an asteroid regolith sample on June 13, 2010. This paper describes NASA/JPL's participation in the Hayabusa mission during the last 100 days of its mission, wherein JPL provided tracking data and orbit determination, plus verification of maneuver design and entry, descent and landing.

  19. Physical property measurements on analog granites related to the joint verification experiment

    NASA Astrophysics Data System (ADS)

    Martin, Randolph J., III; Coyner, Karl B.; Haupt, Robert W.

    1990-08-01

    A key element in JVE (Joint Verification Experiment) conducted jointly between the United States and the USSR is the analysis of the geology and physical properties of the rocks in the respective test sites. A study was initiated to examine unclassified crystalline rock specimens obtained from areas near the Soviet site, Semipalatinsk and appropriate analog samples selected from Mt. Katadin, Maine. These rocks were also compared to Sierra White and Westerly Granite which have been studied in great detail. Measurements performed to characterize these rocks were: (1) Uniaxial strain with simultaneous compressional and shear wave velocities; (2) Hydrostatic compression to 150 MPa with simultaneous compressional and shear wave velocities; (3) Attenuation measurements as a function of frequency and strain amplitude for both dry and water saturated conditions. Elastic moduli determined from the hydrostatic compression and uniaxial strain test show that the rock matrix/mineral properties were comparable in magnitudes which vary within 25 percent from sample to sample. These properties appear to be approximately isotropic, especially at high pressures. However, anisotropy evident for certain samples at pressures below 35 MPa is attributed to dominant pre-existing microcrack populations and their alignments. Dependence of extensional attenuation and Young's modulus on strain amplitude were experimentally determined for intact Sierra White granite using the hysteresis loop technique.

  20. Clinical verification of genetic results returned to research participants: findings from a Colon Cancer Family Registry.

    PubMed

    Laurino, Mercy Y; Truitt, Anjali R; Tenney, Lederle; Fisher, Douglass; Lindor, Noralane M; Veenstra, David; Jarvik, Gail P; Newcomb, Polly A; Fullerton, Stephanie M

    2017-11-01

    The extent to which participants act to clinically verify research results is largely unknown. This study examined whether participants who received Lynch syndrome (LS)-related findings pursued researchers' recommendation to clinically verify results with testing performed by a CLIA-certified laboratory. The Fred Hutchinson Cancer Research Center site of the multinational Colon Cancer Family Registry offered non-CLIA individual genetic research results to select registry participants (cases and their enrolled relatives) from 2011 to 2013. Participants who elected to receive results were counseled on the importance of verifying results at a CLIA-certified laboratory. Twenty-six (76.5%) of the 34 participants who received genetic results completed 2- and 12-month postdisclosure surveys; 42.3% of these (11/26) participated in a semistructured follow-up interview. Within 12 months of result disclosure, only 4 (15.4%) of 26 participants reported having verified their results in a CLIA-certified laboratory; of these four cases, all research and clinical results were concordant. Reasons for pursuing clinical verification included acting on the recommendation of the research team and informing future clinical care. Those who did not verify results cited lack of insurance coverage and limited perceived personal benefit of clinical verification as reasons for inaction. These findings suggest researchers will need to address barriers to seeking clinical verification in order to ensure that the intended benefits of returning genetic research results are realized. © 2017 The Authors. Molecular Genetics & Genomic Medicine published by Wiley Periodicals, Inc.

  1. ENVIRONMENTAL TECHNOLOGY VERIFICATION OF URBAN RUNOFF MODELS

    EPA Science Inventory

    This paper will present the verification process and available results of the XP-SWMM modeling system produced by XP-Software conducted unde the USEPA's ETV Program. Wet weather flow (WWF) models are used throughout the US for the evaluation of storm and combined sewer systems. M...

  2. Version 2.0 Visual Sample Plan (VSP): UXO Module Code Description and Verification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gilbert, Richard O.; Wilson, John E.; O'Brien, Robert F.

    2003-05-06

    The Pacific Northwest National Laboratory (PNNL) is developing statistical methods for determining the amount of geophysical surveys conducted along transects (swaths) that are needed to achieve specified levels of confidence of finding target areas (TAs) of anomalous readings and possibly unexploded ordnance (UXO) at closed, transferring and transferred (CTT) Department of Defense (DoD) ranges and other sites. The statistical methods developed by PNNL have been coded into the UXO module of the Visual Sample Plan (VSP) software code that is being developed by PNNL with support from the DoD, the U.S. Department of Energy (DOE, and the U.S. Environmental Protectionmore » Agency (EPA). (The VSP software and VSP Users Guide (Hassig et al, 2002) may be downloaded from http://dqo.pnl.gov/vsp.) This report describes and documents the statistical methods developed and the calculations and verification testing that have been conducted to verify that VSPs implementation of these methods is correct and accurate.« less

  3. Gaia challenging performances verification: combination of spacecraft models and test results

    NASA Astrophysics Data System (ADS)

    Ecale, Eric; Faye, Frédéric; Chassat, François

    2016-08-01

    To achieve the ambitious scientific objectives of the Gaia mission, extremely stringent performance requirements have been given to the spacecraft contractor (Airbus Defence and Space). For a set of those key-performance requirements (e.g. end-of-mission parallax, maximum detectable magnitude, maximum sky density or attitude control system stability), this paper describes how they are engineered during the whole spacecraft development process, with a focus on the end-to-end performance verification. As far as possible, performances are usually verified by end-to-end tests onground (i.e. before launch). However, the challenging Gaia requirements are not verifiable by such a strategy, principally because no test facility exists to reproduce the expected flight conditions. The Gaia performance verification strategy is therefore based on a mix between analyses (based on spacecraft models) and tests (used to directly feed the models or to correlate them). Emphasis is placed on how to maximize the test contribution to performance verification while keeping the test feasible within an affordable effort. In particular, the paper highlights the contribution of the Gaia Payload Module Thermal Vacuum test to the performance verification before launch. Eventually, an overview of the in-flight payload calibration and in-flight performance verification is provided.

  4. [Uniqueness seeking behavior as a self-verification: an alternative approach to the study of uniqueness].

    PubMed

    Yamaoka, S

    1995-06-01

    Uniqueness theory explains that extremely high perceived similarity between self and others evokes negative emotional reactions and causes uniqueness seeking behavior. However, the theory conceptualizes similarity so ambiguously that it appears to suffer from low predictive validity. The purpose of the current article is to propose an alternative explanation of uniqueness seeking behavior. It posits that perceived uniqueness deprivation is a threat to self-concepts, and therefore causes self-verification behavior. Two levels of self verification are conceived: one based on personal categorization and the other on social categorization. The present approach regards uniqueness seeking behavior as the personal-level self verification. To test these propositions, a 2 (very high or moderate similarity information) x 2 (with or without outgroup information) x 2 (high or low need for uniqueness) between-subject factorial-design experiment was conducted with 95 university students. Results supported the self-verification approach, and were discussed in terms of effects of uniqueness deprivation, levels of self-categorization, and individual differences in need for uniqueness.

  5. Self-verification and contextualized self-views.

    PubMed

    Chen, Serena; English, Tammy; Peng, Kaiping

    2006-07-01

    Whereas most self-verification research has focused on people's desire to verify their global self-conceptions, the present studies examined self-verification with regard to contextualized selfviews-views of the self in particular situations and relationships. It was hypothesized that individuals whose core self-conceptions include contextualized self-views should seek to verify these self-views. In Study 1, the more individuals defined the self in dialectical terms, the more their judgments were biased in favor of verifying over nonverifying feedback about a negative, situation-specific self-view. In Study 2, consistent with research on gender differences in the importance of relationships to the self-concept, women but not men showed a similar bias toward feedback about a negative, relationship-specific self-view, a pattern not seen for global self-views. Together, the results support the notion that self-verification occurs for core self-conceptions, whatever form(s) they may take. Individual differences in self-verification and the nature of selfhood and authenticity are discussed.

  6. You Can't See the Real Me: Attachment Avoidance, Self-Verification, and Self-Concept Clarity.

    PubMed

    Emery, Lydia F; Gardner, Wendi L; Carswell, Kathleen L; Finkel, Eli J

    2018-03-01

    Attachment shapes people's experiences in their close relationships and their self-views. Although attachment avoidance and anxiety both undermine relationships, past research has primarily emphasized detrimental effects of anxiety on the self-concept. However, as partners can help people maintain stable self-views, avoidant individuals' negative views of others might place them at risk for self-concept confusion. We hypothesized that avoidance would predict lower self-concept clarity and that less self-verification from partners would mediate this association. Attachment avoidance was associated with lower self-concept clarity (Studies 1-5), an effect that was mediated by low self-verification (Studies 2-3). The association between avoidance and self-verification was mediated by less self-disclosure and less trust in partner feedback (Study 4). Longitudinally, avoidance predicted changes in self-verification, which in turn predicted changes in self-concept clarity (Study 5). Thus, avoidant individuals' reluctance to trust or become too close to others may result in hidden costs to the self-concept.

  7. Resolution verification targets for airborne and spaceborne imaging systems at the Stennis Space Center

    NASA Astrophysics Data System (ADS)

    McKellip, Rodney; Yuan, Ding; Graham, William; Holland, Donald E.; Stone, David; Walser, William E.; Mao, Chengye

    1997-06-01

    The number of available spaceborne and airborne systems will dramatically increase over the next few years. A common systematic approach toward verification of these systems will become important for comparing the systems' operational performance. The Commercial Remote Sensing Program at the John C. Stennis Space Center (SSC) in Mississippi has developed design requirements for a remote sensing verification target range to provide a means to evaluate spatial, spectral, and radiometric performance of optical digital remote sensing systems. The verification target range consists of spatial, spectral, and radiometric targets painted on a 150- by 150-meter concrete pad located at SSC. The design criteria for this target range are based upon work over a smaller, prototypical target range at SSC during 1996. This paper outlines the purpose and design of the verification target range based upon an understanding of the systems to be evaluated as well as data analysis results from the prototypical target range.

  8. The formal verification of generic interpreters

    NASA Technical Reports Server (NTRS)

    Windley, P.; Levitt, K.; Cohen, G. C.

    1991-01-01

    The task assignment 3 of the design and validation of digital flight control systems suitable for fly-by-wire applications is studied. Task 3 is associated with formal verification of embedded systems. In particular, results are presented that provide a methodological approach to microprocessor verification. A hierarchical decomposition strategy for specifying microprocessors is also presented. A theory of generic interpreters is presented that can be used to model microprocessor behavior. The generic interpreter theory abstracts away the details of instruction functionality, leaving a general model of what an interpreter does.

  9. Considerations in STS payload environmental verification

    NASA Technical Reports Server (NTRS)

    Keegan, W. B.

    1978-01-01

    The current philosophy of the GSFS regarding environmental verification of Shuttle payloads is reviewed. In the structures area, increased emphasis will be placed on the use of analysis for design verification, with selective testing performed as necessary. Furthermore, as a result of recent cost optimization analysis, the multitier test program will presumably give way to a comprehensive test program at the major payload subassembly level after adequate workmanship at the component level has been verified. In the thermal vacuum area, thought is being given to modifying the approaches used for conventional spacecraft.

  10. Formal design and verification of a reliable computing platform for real-time control. Phase 2: Results

    NASA Technical Reports Server (NTRS)

    Butler, Ricky W.; Divito, Ben L.

    1992-01-01

    The design and formal verification of the Reliable Computing Platform (RCP), a fault tolerant computing system for digital flight control applications is presented. The RCP uses N-Multiply Redundant (NMR) style redundancy to mask faults and internal majority voting to flush the effects of transient faults. The system is formally specified and verified using the Ehdm verification system. A major goal of this work is to provide the system with significant capability to withstand the effects of High Intensity Radiated Fields (HIRF).

  11. Experimental preparation and verification of quantum money

    NASA Astrophysics Data System (ADS)

    Guan, Jian-Yu; Arrazola, Juan Miguel; Amiri, Ryan; Zhang, Weijun; Li, Hao; You, Lixing; Wang, Zhen; Zhang, Qiang; Pan, Jian-Wei

    2018-03-01

    A quantum money scheme enables a trusted bank to provide untrusted users with verifiable quantum banknotes that cannot be forged. In this work, we report a proof-of-principle experimental demonstration of the preparation and verification of unforgeable quantum banknotes. We employ a security analysis that takes experimental imperfections fully into account. We measure a total of 3.6 ×106 states in one verification round, limiting the forging probability to 10-7 based on the security analysis. Our results demonstrate the feasibility of preparing and verifying quantum banknotes using currently available experimental techniques.

  12. Modeling and Analysis of Asynchronous Systems Using SAL and Hybrid SAL

    NASA Technical Reports Server (NTRS)

    Tiwari, Ashish; Dutertre, Bruno

    2013-01-01

    We present formal models and results of formal analysis of two different asynchronous systems. We first examine a mid-value select module that merges the signals coming from three different sensors that are each asynchronously sampling the same input signal. We then consider the phase locking protocol proposed by Daly, Hopkins, and McKenna. This protocol is designed to keep a set of non-faulty (asynchronous) clocks phase locked even in the presence of Byzantine-faulty clocks on the network. All models and verifications have been developed using the SAL model checking tools and the Hybrid SAL abstractor.

  13. Boundary element analysis of post-tensioned slabs

    NASA Astrophysics Data System (ADS)

    Rashed, Youssef F.

    2015-06-01

    In this paper, the boundary element method is applied to carry out the structural analysis of post-tensioned flat slabs. The shear-deformable plate-bending model is employed. The effect of the pre-stressing cables is taken into account via the equivalent load method. The formulation is automated using a computer program, which uses quadratic boundary elements. Verification samples are presented, and finally a practical application is analyzed where results are compared against those obtained from the finite element method. The proposed method is efficient in terms of computer storage and processing time as well as the ease in data input and modifications.

  14. Laboratory verification respiratory measurements. IMBLMS phase B.4, appendix C, section 13

    NASA Technical Reports Server (NTRS)

    1970-01-01

    The B-4 IMBLMS preliminary design of the respiratory measurement element includes certain techniques and apparatus which are quite different from those included in the B-3 version previously delivered to NASA-MSC. A working model was constructed in the laboratory to prove the feasibility of certain key features. The most critical of these is the capability of switching sample gases into the mass spectrometer from two different sources during a single breath cycle. Results proved the feasibility of all of the concepts which were tested, and certain refinements and improvements were included, as well.

  15. Strategy for 90% autoverification of clinical chemistry and immunoassay test results using six sigma process improvement.

    PubMed

    Randell, Edward W; Short, Garry; Lee, Natasha; Beresford, Allison; Spencer, Margaret; Kennell, Marina; Moores, Zoë; Parry, David

    2018-06-01

    Six Sigma involves a structured process improvement strategy that places processes on a pathway to continued improvement. The data presented here summarizes a project that took three clinical laboratories from autoverification processes that allowed between about 40% to 60% of tests being auto-verified to more than 90% of tests and samples auto-verified. The project schedule, metrics and targets, a description of the previous system and detailed information on the changes made to achieve greater than 90% auto-verification is presented for this Six Sigma DMAIC (Design, Measure, Analyze, Improve, Control) process improvement project.

  16. TeleOperator/telePresence System (TOPS) Concept Verification Model (CVM) development

    NASA Technical Reports Server (NTRS)

    Shimamoto, Mike S.

    1993-01-01

    The development of an anthropomorphic, undersea manipulator system, the TeleOperator/telePresence System (TOPS) Concept Verification Model (CVM) is described. The TOPS system's design philosophy, which results from NRaD's experience in undersea vehicles and manipulator systems development and operations, is presented. The TOPS design approach, task teams, manipulator, and vision system development and results, conclusions, and recommendations are presented.

  17. Statement Verification: A Stochastic Model of Judgment and Response.

    ERIC Educational Resources Information Center

    Wallsten, Thomas S.; Gonzalez-Vallejo, Claudia

    1994-01-01

    A stochastic judgment model (SJM) is presented as a framework for addressing issues in statement verification and probability judgment. Results of 5 experiments with 264 undergraduates support the validity of the model and provide new information that is interpreted in terms of the SJM. (SLD)

  18. Independent verification and validation report of Washington state ferries' wireless high speed data project

    DOT National Transportation Integrated Search

    2008-06-30

    The following Independent Verification and Validation (IV&V) report documents and presents the results of a study of the Washington State Ferries Prototype Wireless High Speed Data Network. The purpose of the study was to evaluate and determine if re...

  19. 42 CFR 493.1253 - Standard: Establishment and verification of performance specifications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Standard: Establishment and verification of..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS... of test results for the test system. (vi) Reference intervals (normal values). (vii) Any other...

  20. ENVIRONMENTAL TECHNOLOGY VERIFICATION: A VEHICLE FOR INDEPENDENT, CREDIBLE PERFORMANCE RESULTS ON COMMERCIALLY READY TECHNOLOGIES

    EPA Science Inventory

    The paper discusses the U. S. Environmental Protection Agency's Environmental Technology Verification (ETV) Program: its history, operations, past successes, and future plans. Begun in 1995 in response to President Clinton's "Bridge to a Sustainable Future" as a means to work wit...

  1. Dosimetric accuracy of Kodak EDR2 film for IMRT verifications.

    PubMed

    Childress, Nathan L; Salehpour, Mohammad; Dong, Lei; Bloch, Charles; White, R Allen; Rosen, Isaac I

    2005-02-01

    Patient-specific intensity-modulated radiotherapy (IMRT) verifications require an accurate two-dimensional dosimeter that is not labor-intensive. We assessed the precision and reproducibility of film calibrations over time, measured the elemental composition of the film, measured the intermittency effect, and measured the dosimetric accuracy and reproducibility of calibrated Kodak EDR2 film for single-beam verifications in a solid water phantom and for full-plan verifications in a Rexolite phantom. Repeated measurements of the film sensitometric curve in a single experiment yielded overall uncertainties in dose of 2.1% local and 0.8% relative to 300 cGy. 547 film calibrations over an 18-month period, exposed to a range of doses from 0 to a maximum of 240 MU or 360 MU and using 6 MV or 18 MV energies, had optical density (OD) standard deviations that were 7%-15% of their average values. This indicates that daily film calibrations are essential when EDR2 film is used to obtain absolute dose results. An elemental analysis of EDR2 film revealed that it contains 60% as much silver and 20% as much bromine as Kodak XV2 film. EDR2 film also has an unusual 1.69:1 silver:halide molar ratio, compared with the XV2 film's 1.02:1 ratio, which may affect its chemical reactions. To test EDR2's intermittency effect, the OD generated by a single 300 MU exposure was compared to the ODs generated by exposing the film 1 MU, 2 MU, and 4 MU at a time to a total of 300 MU. An ion chamber recorded the relative dose of all intermittency measurements to account for machine output variations. Using small MU bursts to expose the film resulted in delivery times of 4 to 14 minutes and lowered the film's OD by approximately 2% for both 6 and 18 MV beams. This effect may result in EDR2 film underestimating absolute doses for patient verifications that require long delivery times. After using a calibration to convert EDR2 film's OD to dose values, film measurements agreed within 2% relative difference and 2 mm criteria to ion chamber measurements for both sliding window and step-and-shoot fluence map verifications. Calibrated film results agreed with ion chamber measurements to within 5 % /2 mm criteria for transverse-plane full-plan verifications, but were consistently low. When properly calibrated, EDR2 film can be an adequate two-dimensional dosimeter for IMRT verifications, although it may underestimate doses in regions with long exposure times.

  2. A New Integrated Threshold Selection Methodology for Spatial Forecast Verification of Extreme Events

    NASA Astrophysics Data System (ADS)

    Kholodovsky, V.

    2017-12-01

    Extreme weather and climate events such as heavy precipitation, heat waves and strong winds can cause extensive damage to the society in terms of human lives and financial losses. As climate changes, it is important to understand how extreme weather events may change as a result. Climate and statistical models are often independently used to model those phenomena. To better assess performance of the climate models, a variety of spatial forecast verification methods have been developed. However, spatial verification metrics that are widely used in comparing mean states, in most cases, do not have an adequate theoretical justification to benchmark extreme weather events. We proposed a new integrated threshold selection methodology for spatial forecast verification of extreme events that couples existing pattern recognition indices with high threshold choices. This integrated approach has three main steps: 1) dimension reduction; 2) geometric domain mapping; and 3) thresholds clustering. We apply this approach to an observed precipitation dataset over CONUS. The results are evaluated by displaying threshold distribution seasonally, monthly and annually. The method offers user the flexibility of selecting a high threshold that is linked to desired geometrical properties. The proposed high threshold methodology could either complement existing spatial verification methods, where threshold selection is arbitrary, or be directly applicable in extreme value theory.

  3. Evaluation of the 29-km Eta Model for Weather Support to the United States Space Program

    NASA Technical Reports Server (NTRS)

    Manobianco, John; Nutter, Paul

    1997-01-01

    The Applied Meteorology Unit (AMU) conducted a year-long evaluation of NCEP's 29-km mesoscale Eta (meso-eta) weather prediction model in order to identify added value to forecast operations in support of the United States space program. The evaluation was stratified over warm and cool seasons and considered both objective and subjective verification methodologies. Objective verification results generally indicate that meso-eta model point forecasts at selected stations exhibit minimal error growth in terms of RMS errors and are reasonably unbiased. Conversely, results from the subjective verification demonstrate that model forecasts of developing weather events such as thunderstorms, sea breezes, and cold fronts, are not always as accurate as implied by the seasonal error statistics. Sea-breeze case studies reveal that the model generates a dynamically-consistent thermally direct circulation over the Florida peninsula, although at a larger scale than observed. Thunderstorm verification reveals that the meso-eta model is capable of predicting areas of organized convection, particularly during the late afternoon hours but is not capable of forecasting individual thunderstorms. Verification of cold fronts during the cool season reveals that the model is capable of forecasting a majority of cold frontal passages through east central Florida to within +1-h of observed frontal passage.

  4. An Extended Objective Evaluation of the 29-km Eta Model for Weather Support to the United States Space Program

    NASA Technical Reports Server (NTRS)

    Nutter, Paul; Manobianco, John

    1998-01-01

    This report describes the Applied Meteorology Unit's objective verification of the National Centers for Environmental Prediction 29-km eta model during separate warm and cool season periods from May 1996 through January 1998. The verification of surface and upper-air point forecasts was performed at three selected stations important for 45th Weather Squadron, Spaceflight Meteorology Group, and National Weather Service, Melbourne operational weather concerns. The statistical evaluation identified model biases that may result from inadequate parameterization of physical processes. Since model biases are relatively small compared to the random error component, most of the total model error results from day-to-day variability in the forecasts and/or observations. To some extent, these nonsystematic errors reflect the variability in point observations that sample spatial and temporal scales of atmospheric phenomena that cannot be resolved by the model. On average, Meso-Eta point forecasts provide useful guidance for predicting the evolution of the larger scale environment. A more substantial challenge facing model users in real time is the discrimination of nonsystematic errors that tend to inflate the total forecast error. It is important that model users maintain awareness of ongoing model changes. Such changes are likely to modify the basic error characteristics, particularly near the surface.

  5. Ultrasonic Phased Array Compressive Imaging in Time and Frequency Domain: Simulation, Experimental Verification and Real Application

    PubMed Central

    Bai, Zhiliang; Chen, Shili; Jia, Lecheng; Zeng, Zhoumo

    2018-01-01

    Embracing the fact that one can recover certain signals and images from far fewer measurements than traditional methods use, compressive sensing (CS) provides solutions to huge amounts of data collection in phased array-based material characterization. This article describes how a CS framework can be utilized to effectively compress ultrasonic phased array images in time and frequency domains. By projecting the image onto its Discrete Cosine transform domain, a novel scheme was implemented to verify the potentiality of CS for data reduction, as well as to explore its reconstruction accuracy. The results from CIVA simulations indicate that both time and frequency domain CS can accurately reconstruct array images using samples less than the minimum requirements of the Nyquist theorem. For experimental verification of three types of artificial flaws, although a considerable data reduction can be achieved with defects clearly preserved, it is currently impossible to break Nyquist limitation in the time domain. Fortunately, qualified recovery in the frequency domain makes it happen, meaning a real breakthrough for phased array image reconstruction. As a case study, the proposed CS procedure is applied to the inspection of an engine cylinder cavity containing different pit defects and the results show that orthogonal matching pursuit (OMP)-based CS guarantees the performance for real application. PMID:29738452

  6. Investigations on the magnetization behavior of magnetic composite particles

    NASA Astrophysics Data System (ADS)

    Eichholz, Christian; Knoll, Johannes; Lerche, Dietmar; Nirschl, Hermann

    2014-11-01

    In life sciences the application of surface functionalized magnetic composite particles is establishing in diagnostics and in downstream processing of modern biotechnology. These magnetic composite particles consist of non-magnetic material, e.g. polystyrene, which serves as a matrix for the second magnetic component, usually colloidal magnetite. Because of the multitude of magnetic cores these magnetic beads show a complex magnetization behavior which cannot be described with the available approaches for homogeneous magnetic material. Therefore, in this work a new model for the magnetization behavior of magnetic composite particles is developed. By introducing an effective magnetization and considering an overall demagnetization factor the deviation of the demagnetization of homogeneously magnetized particles is taken into account. Calculated and experimental results show a good agreement which allows for the verification of the adapted model of particle magnetization. Besides, a newly developed magnetic analyzing centrifuge is used for the characterization of magnetic composite particle systems. The experimental results, also used for the model verification, give both, information about the magnetic properties and the interaction behavior of particle systems. By adding further components to the particle solution, such as salts or proteins, industrial relevant systems can be reconstructed. The analyzing tool can be used to adapt industrial processes without time-consuming preliminary tests with large samples in the process equipments.

  7. 30 CFR 250.913 - When must I resubmit Platform Verification Program plans?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Structures Platform Verification Program § 250.913 When must I resubmit Platform Verification Program plans? (a) You must resubmit any design verification, fabrication verification, or installation verification... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When must I resubmit Platform Verification...

  8. Guidance and Control Software Project Data - Volume 3: Verification Documents

    NASA Technical Reports Server (NTRS)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the verification documents from the GCS project. Volume 3 contains four appendices: A. Software Verification Cases and Procedures for the Guidance and Control Software Project; B. Software Verification Results for the Pluto Implementation of the Guidance and Control Software; C. Review Records for the Pluto Implementation of the Guidance and Control Software; and D. Test Results Logs for the Pluto Implementation of the Guidance and Control Software.

  9. [Tobacco quality analysis of industrial classification of different years using near-infrared (NIR) spectrum].

    PubMed

    Wang, Yi; Xiang, Ma; Wen, Ya-Dong; Yu, Chun-Xia; Wang, Luo-Ping; Zhao, Long-Lian; Li, Jun-Hui

    2012-11-01

    In this study, tobacco quality analysis of main Industrial classification of different years was carried out applying spectrum projection and correlation methods. The group of data was near-infrared (NIR) spectrum from Hongta Tobacco (Group) Co., Ltd. 5730 tobacco leaf Industrial classification samples from Yuxi in Yunnan province from 2007 to 2010 year were collected using near infrared spectroscopy, which from different parts and colors and all belong to tobacco varieties of HONGDA. The conclusion showed that, when the samples were divided to two part by the ratio of 2:1 randomly as analysis and verification sets in the same year, the verification set corresponded with the analysis set applying spectrum projection because their correlation coefficients were above 0.98. The correlation coefficients between two different years applying spectrum projection were above 0.97. The highest correlation coefficient was the one between 2008 and 2009 year and the lowest correlation coefficient was the one between 2007 and 2010 year. At the same time, The study discussed a method to get the quantitative similarity values of different industrial classification samples. The similarity and consistency values were instructive in combination and replacement of tobacco leaf blending.

  10. Biometric verification in dynamic writing

    NASA Astrophysics Data System (ADS)

    George, Susan E.

    2002-03-01

    Pen-tablet devices capable of capturing the dynamics of writing record temporal and pressure information as well as the spatial pattern. This paper explores biometric verification based upon the dynamics of writing where writers are distinguished not on the basis of what they write (ie the signature), but how they write. We have collected samples of dynamic writing from 38 Chinese writers. Each writer was asked to provide 10 copies of a paragraph of text and the same number of signature samples. From the data we have extracted stroke-based primitives from the sentence data utilizing pen-up/down information and heuristic rules about the shape of the character. The x, y and pressure values of each primitive were interpolated into an even temporal range based upon a 20 msec sampling rate. We applied the Daubechies 1 wavelet transform to the x signal, y signal and pressure signal using the coefficients as inputs to a multi-layer perceptron trained with back-propagation on the sentence data. We found a sensitivity of 0.977 and specificity of 0.990 recognizing writers based on test primitives extracted from sentence data and measures of 0.916 and 0.961 respectively, from test primitives extracted from signature data.

  11. Development and Verification of the Charring Ablating Thermal Protection Implicit System Solver

    NASA Technical Reports Server (NTRS)

    Amar, Adam J.; Calvert, Nathan D.; Kirk, Benjamin S.

    2010-01-01

    The development and verification of the Charring Ablating Thermal Protection Implicit System Solver is presented. This work concentrates on the derivation and verification of the stationary grid terms in the equations that govern three-dimensional heat and mass transfer for charring thermal protection systems including pyrolysis gas flow through the porous char layer. The governing equations are discretized according to the Galerkin finite element method with first and second order implicit time integrators. The governing equations are fully coupled and are solved in parallel via Newton's method, while the fully implicit linear system is solved with the Generalized Minimal Residual method. Verification results from exact solutions and the Method of Manufactured Solutions are presented to show spatial and temporal orders of accuracy as well as nonlinear convergence rates.

  12. A preliminary study on the use of FX-Glycine gel and an in-house optical cone beam CT readout for IMRT and RapidArc verification

    NASA Astrophysics Data System (ADS)

    Ravindran, Paul B.; Ebenezer, Suman Babu S.; Winfred, Michael Raj; Amalan, S.

    2017-05-01

    The radiochromic FX gel with Optical CT readout has been investigated by several authors and has shown promising results for 3D dosimetry. One of the applications of the gel dosimeters is their use in 3D dose verification for IMRT and RapidArc quality assurance. Though polymer gel has been used successfully for clinical dose verification, the use of FX gel for clinical dose verification with optical cone beam CT needs further validation. In this work, we have used FX gel and an in- house optical readout system for gamma analysis between the dose matrices of measured dose distribution and a treatment planning system (TPS) calculated dose distribution for a few test cases.

  13. Development and Verification of the Charring, Ablating Thermal Protection Implicit System Simulator

    NASA Technical Reports Server (NTRS)

    Amar, Adam J.; Calvert, Nathan; Kirk, Benjamin S.

    2011-01-01

    The development and verification of the Charring Ablating Thermal Protection Implicit System Solver (CATPISS) is presented. This work concentrates on the derivation and verification of the stationary grid terms in the equations that govern three-dimensional heat and mass transfer for charring thermal protection systems including pyrolysis gas flow through the porous char layer. The governing equations are discretized according to the Galerkin finite element method (FEM) with first and second order fully implicit time integrators. The governing equations are fully coupled and are solved in parallel via Newton s method, while the linear system is solved via the Generalized Minimum Residual method (GMRES). Verification results from exact solutions and Method of Manufactured Solutions (MMS) are presented to show spatial and temporal orders of accuracy as well as nonlinear convergence rates.

  14. Information verification and encryption based on phase retrieval with sparsity constraints and optical inference

    NASA Astrophysics Data System (ADS)

    Zhong, Shenlu; Li, Mengjiao; Tang, Xiajie; He, Weiqing; Wang, Xiaogang

    2017-01-01

    A novel optical information verification and encryption method is proposed based on inference principle and phase retrieval with sparsity constraints. In this method, a target image is encrypted into two phase-only masks (POMs), which comprise sparse phase data used for verification. Both of the two POMs need to be authenticated before being applied for decrypting. The target image can be optically reconstructed when the two authenticated POMs are Fourier transformed and convolved by the correct decryption key, which is also generated in encryption process. No holographic scheme is involved in the proposed optical verification and encryption system and there is also no problem of information disclosure in the two authenticable POMs. Numerical simulation results demonstrate the validity and good performance of this new proposed method.

  15. Atmospheric transport modelling in support of CTBT verification—overview and basic concepts

    NASA Astrophysics Data System (ADS)

    Wotawa, Gerhard; De Geer, Lars-Erik; Denier, Philippe; Kalinowski, Martin; Toivonen, Harri; D'Amours, Real; Desiato, Franco; Issartel, Jean-Pierre; Langer, Matthias; Seibert, Petra; Frank, Andreas; Sloan, Craig; Yamazawa, Hiromi

    Under the provisions of the Comprehensive Nuclear-Test-Ban Treaty (CTBT), a global monitoring system comprising different verification technologies is currently being set up. The network will include 80 radionuclide (RN) stations distributed all over the globe that measure treaty-relevant radioactive species. While the seismic subsystem cannot distinguish between chemical and nuclear explosions, RN monitoring would provide the "smoking gun" of a possible treaty violation. Atmospheric transport modelling (ATM) will be an integral part of CTBT verification, since it provides a geo-temporal location capability for the RN technology. In this paper, the basic concept for the future ATM software system to be installed at the International Data Centre is laid out. The system is based on the operational computation of multi-dimensional source-receptor sensitivity fields for all RN samples by means of adjoint tracer transport modelling. While the source-receptor matrix methodology has already been applied in the past, the system that we suggest will be unique and unprecedented, since it is global, real-time and aims at uncovering source scenarios that are compatible with measurements. Furthermore, it has to deal with source dilution ratios that are by orders of magnitude larger than in typical transport model applications. This new verification software will need continuous scientific attention, and may well provide a prototype system for future applications in areas of environmental monitoring, emergency response and verification of other international agreements and treaties.

  16. Remaining Sites Verification Package for the 1607-B1 Septic System, Waste Site Reclassification Form 2007-015

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    L. M. Dittmer

    2007-08-30

    The 1607-B1 Septic System includes a septic tank, drain field, and associated connecting pipelines and influent sanitary sewer lines. This septic system serviced the former 1701-B Badgehouse, 1720-B Patrol Building/Change Room, and the 1709-B Fire Headquarters. The 1607-B1 waste site received unknown amounts of nonhazardous, nonradioactive sanitary sewage from these facilities during its operational history from 1944 to approximately 1970. In accordance with this evaluation, the confirmatory sampling results support a reclassification of this site to No Action. The current site conditions achieve the remedial action objectives and the corresponding remedial action goals established in the Remaining Sites ROD. Themore » results of confirmatory sampling show that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also demonstrate that residual contaminant concentrations are protective of groundwater and the Columbia River.« less

  17. 7 CFR 245.6a - Verification requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AGRICULTURE CHILD NUTRITION PROGRAMS DETERMINING ELIGIBILITY FOR FREE AND REDUCED PRICE MEALS AND FREE MILK IN... agencies serving foster, homeless, migrant, or runaway children, as defined in § 245.2. Agency records may...) General. The local educational agency must verify eligibility of children in a sample of household...

  18. 36 CFR 1237.28 - What special concerns apply to digital photographs?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... defects, evaluate the accuracy of finding aids, and verify file header information and file name integrity... sampling methods or more comprehensive verification systems (e.g., checksum programs), to evaluate image.... For permanent or unscheduled images descriptive elements must include: (1) An identification number...

  19. 36 CFR § 1237.28 - What special concerns apply to digital photographs?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... defects, evaluate the accuracy of finding aids, and verify file header information and file name integrity... sampling methods or more comprehensive verification systems (e.g., checksum programs), to evaluate image.... For permanent or unscheduled images descriptive elements must include: (1) An identification number...

  20. 36 CFR 1237.28 - What special concerns apply to digital photographs?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... defects, evaluate the accuracy of finding aids, and verify file header information and file name integrity... sampling methods or more comprehensive verification systems (e.g., checksum programs), to evaluate image.... For permanent or unscheduled images descriptive elements must include: (1) An identification number...

  1. 36 CFR 1237.28 - What special concerns apply to digital photographs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... defects, evaluate the accuracy of finding aids, and verify file header information and file name integrity... sampling methods or more comprehensive verification systems (e.g., checksum programs), to evaluate image.... For permanent or unscheduled images descriptive elements must include: (1) An identification number...

  2. 36 CFR 1237.28 - What special concerns apply to digital photographs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... defects, evaluate the accuracy of finding aids, and verify file header information and file name integrity... sampling methods or more comprehensive verification systems (e.g., checksum programs), to evaluate image.... For permanent or unscheduled images descriptive elements must include: (1) An identification number...

  3. 40 CFR 61.345 - Standards: Containers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...., bungs, hatches, and sampling ports) shall be designed to operate with no detectable emissions as...) The total enclosure must be designed and operated in accordance with the criteria for a permanent total enclosure as specified in section 5 of the “Procedure T—Criteria for and Verification of a...

  4. Climate Verification Using Running Mann Whitney Z Statistics

    USDA-ARS?s Scientific Manuscript database

    A robust method previously used to detect observed intra- to multi-decadal (IMD) climate regimes was adapted to test whether climate models could reproduce IMD variations in U.S. surface temperatures during 1919-2008. This procedure, called the running Mann Whitney Z (MWZ) method, samples data ranki...

  5. Multiple pre- and post-analytical lean approaches to the improvement of the laboratory turnaround time in a large core laboratory.

    PubMed

    Lou, Amy H; Elnenaei, Manal O; Sadek, Irene; Thompson, Shauna; Crocker, Bryan D; Nassar, Bassam A

    2017-10-01

    Core laboratory (CL), as a new business model, facilitates consolidation and integration of laboratory services to enhance efficiency and reduce costs. This study evaluates the impact of total laboratory automation system (TLA), electric track vehicle (ETV) system and auto-verification (AV) of results on overall turnaround time (TAT) (phlebotomy to reporting TAT: PR-TAT) within a CL setting. Mean, median and percentage of outlier (OP) for PR-TAT were compared for pre- and post-CL eras using five representative tests based on different request priorities. Comparison studies were also carried out on the intra-laboratory TAT (in-lab to reporting TAT: IR-TAT) and the delivery TAT (phlebotomy to in-lab TAT: PI-TAT) to reflect the efficiency of the TLA (both before and after introducing result AV) and ETV systems respectively. Median PR-TATs for the urgent samples were reduced on average by 16% across all representative analytes. Median PR-TATs for the routine samples were curtailed by 51%, 50%, 49%, 34% and 22% for urea, potassium, thyroid stimulating hormone (TSH), complete blood count (CBC) and prothrombin time (PT) respectively. The shorter PR-TAT was attributed to a significant reduction of IR-TAT through the TLA. However, the median PI-TAT was delayed when the ETV was used. Application of various AV rules shortened the median IR-TATs for potassium and urea. However, the OP of PR-TAT for the STAT requests exceeding 60min were all higher than those from the pre-CL era. TLA and auto-verification rules help to efficiently manage substantial volumes of urgent and routine samples. However, the ETV application as it stands shows a negative impact on the PR-TAT. Copyright © 2017 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  6. Multi-centre audit of VMAT planning and pre-treatment verification.

    PubMed

    Jurado-Bruggeman, Diego; Hernández, Victor; Sáez, Jordi; Navarro, David; Pino, Francisco; Martínez, Tatiana; Alayrach, Maria-Elena; Ailleres, Norbert; Melero, Alejandro; Jornet, Núria

    2017-08-01

    We performed a multi-centre intercomparison of VMAT dose planning and pre-treatment verification. The aims were to analyse the dose plans in terms of dosimetric quality and deliverability, and to validate whether in-house pre-treatment verification results agreed with those of an external audit. The nine participating centres encompassed different machines, equipment, and methodologies. Two mock cases (prostate and head and neck) were planned using one and two arcs. A plan quality index was defined to compare the plans and different complexity indices were calculated to check their deliverability. We compared gamma index pass rates using the centre's equipment and methodology to those of an external audit (global 3D gamma, absolute dose differences, 10% of maximum dose threshold). Log-file analysis was performed to look for delivery errors. All centres fulfilled the dosimetric goals but plan quality and delivery complexity were heterogeneous and uncorrelated, depending on the manufacturer and the planner's methodology. Pre-treatment verifications results were within tolerance in all cases for gamma 3%-3mm evaluation. Nevertheless, differences between the external audit and in-house measurements arose due to different equipment or methodology, especially for 2%-2mm criteria with differences up to 20%. No correlation was found between complexity indices and verification results amongst centres. All plans fulfilled dosimetric constraints, but plan quality and complexity did not correlate and were strongly dependent on the planner and the vendor. In-house measurements cannot completely replace external audits for credentialing. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Leveraging pattern matching to solve SRAM verification challenges at advanced nodes

    NASA Astrophysics Data System (ADS)

    Kan, Huan; Huang, Lucas; Yang, Legender; Zou, Elaine; Wan, Qijian; Du, Chunshan; Hu, Xinyi; Liu, Zhengfang; Zhu, Yu; Zhang, Recoo; Huang, Elven; Muirhead, Jonathan

    2018-03-01

    Memory is a critical component in today's system-on-chip (SoC) designs. Static random-access memory (SRAM) blocks are assembled by combining intellectual property (IP) blocks that come from SRAM libraries developed and certified by the foundries for both functionality and a specific process node. Customers place these SRAM IP in their designs, adjusting as necessary to achieve DRC-clean results. However, any changes a customer makes to these SRAM IP during implementation, whether intentionally or in error, can impact yield and functionality. Physical verification of SRAM has always been a challenge, because these blocks usually contain smaller feature sizes and spacing constraints compared to traditional logic or other layout structures. At advanced nodes, critical dimension becomes smaller and smaller, until there is almost no opportunity to use optical proximity correction (OPC) and lithography to adjust the manufacturing process to mitigate the effects of any changes. The smaller process geometries, reduced supply voltages, increasing process variation, and manufacturing uncertainty mean accurate SRAM physical verification results are not only reaching new levels of difficulty, but also new levels of criticality for design success. In this paper, we explore the use of pattern matching to create an SRAM verification flow that provides both accurate, comprehensive coverage of the required checks and visual output to enable faster, more accurate error debugging. Our results indicate that pattern matching can enable foundries to improve SRAM manufacturing yield, while allowing designers to benefit from SRAM verification kits that can shorten the time to market.

  8. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, SWINE WASTE ELECTRIC POWER AND HEAT PRODUCTION--MARTIN MACHINERY INTERNAL COMBUSTION ENGINE

    EPA Science Inventory

    Under EPA’s Environmental Technology Verification program, which provides objective and scientific third party analysis of new technology that can benefit the environment, a combined heat and power system designed by Martin Machinery was evaluated. This paper provides test result...

  9. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, HVLP COATING EQUIPMENT, SHARPE MANUFACTURING COMPANY PLATINUM 2012 HVLP SPRAY GUN

    EPA Science Inventory

    This report presents the results of the verification test of the Sharpe Platinum 2013 high-volume, low-pressure gravity-feed spray gun, hereafter referred to as the Sharpe Platinum, which is designed for use in automotive refinishing. The test coating chosen by Sharpe Manufacturi...

  10. 42 CFR 431.960 - Types of payment errors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... (3) A State eligibility error does not result from the State's verification of an applicant's self-declaration or self-certification of eligibility for, and the correct amount of, medical assistance or child... verification. (2) The difference in payment between what the State paid (as adjusted within improper payment...

  11. The Evolution of Improved Baghouse Filter Media as Observed in the Environmental Technology Verification Program

    EPA Science Inventory

    The U.S. EPA implemented the Environmental Technology Verification (ETV) program in 1995 to generate independent and credible data on the performance of innovative technologies that have the potential to improve protection of public health and the environment. Results are publicl...

  12. Speed and Accuracy in the Processing of False Statements About Semantic Information.

    ERIC Educational Resources Information Center

    Ratcliff, Roger

    1982-01-01

    A standard reaction time procedure and a response signal procedure were used on data from eight experiments on semantic verifications. Results suggest that simple models of the semantic verification task that assume a single yes/no dimension on which discrimination is made are not correct. (Author/PN)

  13. Thermal noise in space-charge-limited hole current in silicon

    NASA Technical Reports Server (NTRS)

    Shumka, A.; Golder, J.; Nicolet, M.

    1972-01-01

    Present theories on noise in single-carrier space-charge-limited currents in solids have not been quantitatively substantiated by experimental evidence. To obtain such experimental verification, the noise in specially fabricated silicon structures is being measured and analyzed. The first results of this verification effort are reported.

  14. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT: PAINT OVERSPRAY ARRESTOR, AAF INTERNATIONAL DRIPAK 90-95%

    EPA Science Inventory

    The report gives results of March 26-29, 1999, tests of AAF International's DriPak 90-95% paint overspray arrestor (POA) as part of an evaluation of POAs by EPA's Air Pollution Control Technology (APCT) Environmental Technology Verification (ETV) Program. The basic performance fa...

  15. Model Checking Satellite Operational Procedures

    NASA Astrophysics Data System (ADS)

    Cavaliere, Federico; Mari, Federico; Melatti, Igor; Minei, Giovanni; Salvo, Ivano; Tronci, Enrico; Verzino, Giovanni; Yushtein, Yuri

    2011-08-01

    We present a model checking approach for the automatic verification of satellite operational procedures (OPs). Building a model for a complex system as a satellite is a hard task. We overcome this obstruction by using a suitable simulator (SIMSAT) for the satellite. Our approach aims at improving OP quality assurance by automatic exhaustive exploration of all possible simulation scenarios. Moreover, our solution decreases OP verification costs by using a model checker (CMurphi) to automatically drive the simulator. We model OPs as user-executed programs observing the simulator telemetries and sending telecommands to the simulator. In order to assess feasibility of our approach we present experimental results on a simple meaningful scenario. Our results show that we can save up to 90% of verification time.

  16. Generic Verification Protocol for Verification of Online Turbidimeters

    EPA Science Inventory

    This protocol provides generic procedures for implementing a verification test for the performance of online turbidimeters. The verification tests described in this document will be conducted under the Environmental Technology Verification (ETV) Program. Verification tests will...

  17. Multibody modeling and verification

    NASA Technical Reports Server (NTRS)

    Wiens, Gloria J.

    1989-01-01

    A summary of a ten week project on flexible multibody modeling, verification and control is presented. Emphasis was on the need for experimental verification. A literature survey was conducted for gathering information on the existence of experimental work related to flexible multibody systems. The first portion of the assigned task encompassed the modeling aspects of flexible multibodies that can undergo large angular displacements. Research in the area of modeling aspects were also surveyed, with special attention given to the component mode approach. Resulting from this is a research plan on various modeling aspects to be investigated over the next year. The relationship between the large angular displacements, boundary conditions, mode selection, and system modes is of particular interest. The other portion of the assigned task was the generation of a test plan for experimental verification of analytical and/or computer analysis techniques used for flexible multibody systems. Based on current and expected frequency ranges of flexible multibody systems to be used in space applications, an initial test article was selected and designed. A preliminary TREETOPS computer analysis was run to ensure frequency content in the low frequency range, 0.1 to 50 Hz. The initial specifications of experimental measurement and instrumentation components were also generated. Resulting from this effort is the initial multi-phase plan for a Ground Test Facility of Flexible Multibody Systems for Modeling Verification and Control. The plan focusses on the Multibody Modeling and Verification (MMV) Laboratory. General requirements of the Unobtrusive Sensor and Effector (USE) and the Robot Enhancement (RE) laboratories were considered during the laboratory development.

  18. Structural damage detection based on stochastic subspace identification and statistical pattern recognition: II. Experimental validation under varying temperature

    NASA Astrophysics Data System (ADS)

    Lin, Y. Q.; Ren, W. X.; Fang, S. E.

    2011-11-01

    Although most vibration-based damage detection methods can acquire satisfactory verification on analytical or numerical structures, most of them may encounter problems when applied to real-world structures under varying environments. The damage detection methods that directly extract damage features from the periodically sampled dynamic time history response measurements are desirable but relevant research and field application verification are still lacking. In this second part of a two-part paper, the robustness and performance of the statistics-based damage index using the forward innovation model by stochastic subspace identification of a vibrating structure proposed in the first part have been investigated against two prestressed reinforced concrete (RC) beams tested in the laboratory and a full-scale RC arch bridge tested in the field under varying environments. Experimental verification is focused on temperature effects. It is demonstrated that the proposed statistics-based damage index is insensitive to temperature variations but sensitive to the structural deterioration or state alteration. This makes it possible to detect the structural damage for the real-scale structures experiencing ambient excitations and varying environmental conditions.

  19. Novel Genetic Variants of Sporadic Atrial Septal Defect (ASD) in a Chinese Population Identified by Whole-Exome Sequencing (WES)

    PubMed Central

    Liu, Yong; Cao, Yu; Li, Yaxiong; Lei, Dongyun; Li, Lin; Hou, Zong Liu; Han, Shen; Meng, Mingyao; Shi, Jianlin; Zhang, Yayong; Wang, Yi; Niu, Zhaoyi; Xie, Yanhua; Xiao, Benshan; Wang, Yuanfei; Li, Xiao; Yang, Lirong

    2018-01-01

    Background Recently, mutations in several genes have been described to be associated with sporadic ASD, but some genetic variants remain to be identified. The aim of this study was to use whole-exome sequencing (WES) combined with bioinformatics analysis to identify novel genetic variants in cases of sporadic congenital ASD, followed by validation by Sanger sequencing. Material/Methods Five Han patients with secundum ASD were recruited, and their tissue samples were analyzed by WES, followed by verification by Sanger sequencing of tissue and blood samples. Further evaluation using blood samples included 452 additional patients with sporadic secundum ASD (212 male and 240 female patients) and 519 healthy subjects (252 male and 267 female subjects) for further verification by a multiplexed MassARRAY system. Bioinformatic analyses were performed to identify novel genetic variants associated with sporadic ASD. Results From five patients with sporadic ASD, a total of 181,762 genomic variants in 33 exon loci, validated by Sanger sequencing, were selected and underwent MassARRAY analysis in 452 patients with ASD and 519 healthy subjects. Three loci with high mutation frequencies, the 138665410 FOXL2 gene variant, the 23862952 MYH6 gene variant, and the 71098693 HYDIN gene variant were found to be significantly associated with sporadic ASD (P<0.05); variants in FOXL2 and MYH6 were found in patients with isolated, sporadic ASD (P<5×10−4). Conclusions This was the first study that demonstrated variants in FOXL2 and HYDIN associated with sporadic ASD, and supported the use of WES and bioinformatics analysis to identify disease-associated mutations. PMID:29505555

  20. Novel Genetic Variants of Sporadic Atrial Septal Defect (ASD) in a Chinese Population Identified by Whole-Exome Sequencing (WES).

    PubMed

    Liu, Yong; Cao, Yu; Li, Yaxiong; Lei, Dongyun; Li, Lin; Hou, Zong Liu; Han, Shen; Meng, Mingyao; Shi, Jianlin; Zhang, Yayong; Wang, Yi; Niu, Zhaoyi; Xie, Yanhua; Xiao, Benshan; Wang, Yuanfei; Li, Xiao; Yang, Lirong; Wang, Wenju; Jiang, Lihong

    2018-03-05

    BACKGROUND Recently, mutations in several genes have been described to be associated with sporadic ASD, but some genetic variants remain to be identified. The aim of this study was to use whole-exome sequencing (WES) combined with bioinformatics analysis to identify novel genetic variants in cases of sporadic congenital ASD, followed by validation by Sanger sequencing. MATERIAL AND METHODS Five Han patients with secundum ASD were recruited, and their tissue samples were analyzed by WES, followed by verification by Sanger sequencing of tissue and blood samples. Further evaluation using blood samples included 452 additional patients with sporadic secundum ASD (212 male and 240 female patients) and 519 healthy subjects (252 male and 267 female subjects) for further verification by a multiplexed MassARRAY system. Bioinformatic analyses were performed to identify novel genetic variants associated with sporadic ASD. RESULTS From five patients with sporadic ASD, a total of 181,762 genomic variants in 33 exon loci, validated by Sanger sequencing, were selected and underwent MassARRAY analysis in 452 patients with ASD and 519 healthy subjects. Three loci with high mutation frequencies, the 138665410 FOXL2 gene variant, the 23862952 MYH6 gene variant, and the 71098693 HYDIN gene variant were found to be significantly associated with sporadic ASD (P<0.05); variants in FOXL2 and MYH6 were found in patients with isolated, sporadic ASD (P<5×10^-4). CONCLUSIONS This was the first study that demonstrated variants in FOXL2 and HYDIN associated with sporadic ASD, and supported the use of WES and bioinformatics analysis to identify disease-associated mutations.

  1. Assessment of Galileo modal test results for mathematical model verification

    NASA Technical Reports Server (NTRS)

    Trubert, M.

    1984-01-01

    The modal test program for the Galileo Spacecraft was completed at the Jet Propulsion Laboratory in the summer of 1983. The multiple sine dwell method was used for the baseline test. The Galileo Spacecraft is a rather complex 2433 kg structure made of a central core on which seven major appendages representing 30 percent of the total mass are attached, resulting in a high modal density structure. The test revealed a strong nonlinearity in several major modes. This nonlinearity discovered in the course of the test necessitated running additional tests at the unusually high response levels of up to about 21 g. The high levels of response were required to obtain a model verification valid at the level of loads for which the spacecraft was designed. Because of the high modal density and the nonlinearity, correlation between the dynamic mathematical model and the test results becomes a difficult task. Significant changes in the pre-test analytical model are necessary to establish confidence in the upgraded analytical model used for the final load verification. This verification, using a test verified model, is required by NASA to fly the Galileo Spacecraft on the Shuttle/Centaur launch vehicle in 1986.

  2. SU-F-T-268: A Feasibility Study of Independent Dose Verification for Vero4DRT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yamashita, M; Kokubo, M; Institute of Biomedical Research and Innovation, Kobe, Hyogo

    2016-06-15

    Purpose: Vero4DRT (Mitsubishi Heavy Industries Ltd.) has been released for a few years. The treatment planning system (TPS) of Vero4DRT is dedicated, so the measurement is the only method of dose verification. There have been no reports of independent dose verification using Clarksonbased algorithm for Vero4DRT. An independent dose verification software program of the general-purpose linac using a modified Clarkson-based algorithm was modified for Vero4DRT. In this study, we evaluated the accuracy of independent dose verification program and the feasibility of the secondary check for Vero4DRT. Methods: iPlan (Brainlab AG) was used as the TPS. PencilBeam Convolution was used formore » dose calculation algorithm of IMRT and X-ray Voxel Monte Carlo was used for the others. Simple MU Analysis (SMU, Triangle Products, Japan) was used as the independent dose verification software program in which CT-based dose calculation was performed using a modified Clarkson-based algorithm. In this study, 120 patients’ treatment plans were collected in our institute. The treatments were performed using the conventional irradiation for lung and prostate, SBRT for lung and Step and shoot IMRT for prostate. Comparison in dose between the TPS and the SMU was done and confidence limits (CLs, Mean ± 2SD %) were compared to those from the general-purpose linac. Results: As the results of the CLs, the conventional irradiation (lung, prostate), SBRT (lung) and IMRT (prostate) show 2.2 ± 3.5% (CL of the general-purpose linac: 2.4 ± 5.3%), 1.1 ± 1.7% (−0.3 ± 2.0%), 4.8 ± 3.7% (5.4 ± 5.3%) and −0.5 ± 2.5% (−0.1 ± 3.6%), respectively. The CLs for Vero4DRT show similar results to that for the general-purpose linac. Conclusion: The independent dose verification for the new linac is clinically available as a secondary check and we performed the check with the similar tolerance level of the general-purpose linac. This research is partially supported by Japan Agency for Medical Research and Development (AMED)« less

  3. Uncertainty Measurement for Trace Element Analysis of Uranium and Plutonium Samples by Inductively Coupled Plasma-Atomic Emission Spectrometry (ICP-AES) and Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gallimore, David L.

    2012-06-13

    The measurement uncertainty estimatino associated with trace element analysis of impurities in U and Pu was evaluated using the Guide to the Expression of Uncertainty Measurement (GUM). I this evalution the uncertainty sources were identified and standard uncertainties for the components were categorized as either Type A or B. The combined standard uncertainty was calculated and a coverage factor k = 2 was applied to obtain the expanded uncertainty, U. The ICP-AES and ICP-MS methods used were deveoped for the multi-element analysis of U and Pu samples. A typical analytical run consists of standards, process blanks, samples, matrix spiked samples,more » post digestion spiked samples and independent calibration verification standards. The uncertainty estimation was performed on U and Pu samples that have been analyzed previously as part of the U and Pu Sample Exchange Programs. Control chart results and data from the U and Pu metal exchange programs were combined with the GUM into a concentration dependent estimate of the expanded uncertainty. Comparison of trace element uncertainties obtained using this model was compared to those obtained for trace element results as part of the Exchange programs. This process was completed for all trace elements that were determined to be above the detection limit for the U and Pu samples.« less

  4. SU-D-BRC-03: Development and Validation of an Online 2D Dose Verification System for Daily Patient Plan Delivery Accuracy Check

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhao, J; Hu, W; Xing, Y

    Purpose: All plan verification systems for particle therapy are designed to do plan verification before treatment. However, the actual dose distributions during patient treatment are not known. This study develops an online 2D dose verification tool to check the daily dose delivery accuracy. Methods: A Siemens particle treatment system with a modulated scanning spot beam is used in our center. In order to do online dose verification, we made a program to reconstruct the delivered 2D dose distributions based on the daily treatment log files and depth dose distributions. In the log files we can get the focus size, positionmore » and particle number for each spot. A gamma analysis is used to compare the reconstructed dose distributions with the dose distributions from the TPS to assess the daily dose delivery accuracy. To verify the dose reconstruction algorithm, we compared the reconstructed dose distributions to dose distributions measured using PTW 729XDR ion chamber matrix for 13 real patient plans. Then we analyzed 100 treatment beams (58 carbon and 42 proton) for prostate, lung, ACC, NPC and chordoma patients. Results: For algorithm verification, the gamma passing rate was 97.95% for the 3%/3mm and 92.36% for the 2%/2mm criteria. For patient treatment analysis,the results were 97.7%±1.1% and 91.7%±2.5% for carbon and 89.9%±4.8% and 79.7%±7.7% for proton using 3%/3mm and 2%/2mm criteria, respectively. The reason for the lower passing rate for the proton beam is that the focus size deviations were larger than for the carbon beam. The average focus size deviations were −14.27% and −6.73% for proton and −5.26% and −0.93% for carbon in the x and y direction respectively. Conclusion: The verification software meets our requirements to check for daily dose delivery discrepancies. Such tools can enhance the current treatment plan and delivery verification processes and improve safety of clinical treatments.« less

  5. Electronic Cigarette Sales to Minors via the Internet

    PubMed Central

    Williams, Rebecca S.; Derrick, Jason; Ribisl, Kurt M.

    2015-01-01

    Importance Electronic cigarettes (e-cigarettes) entered the US market in 2007 and, with little regulatory oversight, grew into a $2-billion-a-year industry by 2013. The Centers for Disease Control and Prevention has reported a trend of increasing e-cigarette use among teens, with use rates doubling from 2011 to 2012. While several studies have documented that teens can and do buy cigarettes online, to our knowledge, no studies have yet examined age verification among Internet tobacco vendors selling e-cigarettes. Objective To estimate the extent to which minors can successfully purchase e-cigarettes online and assess compliance with North Carolina's 2013 e-cigarette age-verification law. Design, Setting, and Participants In this cross-sectional study conducted from February 2014 to June 2014, 11 nonsmoking minors aged 14 to 17 years made supervised e-cigarette purchase attempts from 98 Internet e-cigarette vendors. Purchase attempts were made at the University of North Carolina Internet Tobacco Vendors Study project offices using credit cards. Main Outcome and Measure Rate at which minors can successfully purchase e-cigarettes on the Internet. Results Minors successfully received deliveries of e-cigarettes from 76.5% of purchase attempts, with no attempts by delivery companies to verify their ages at delivery and 95% of delivered orders simply left at the door. All delivered packages came from shipping companies that, according to company policy or federal regulation, do not ship cigarettes to consumers. Of the total orders, 18 failed for reasons unrelated to age verification. Only 5 of the remaining 80 youth purchase attempts were rejected owing to age verification, resulting in a youth buy rate of 93.7%. None of the vendors complied with North Carolina's e-cigarette age-verification law. Conclusions and Relevance Minors are easily able to purchase e-cigarettes from the Internet because of an absence of age-verification measures used by Internet e-cigarette vendors. Federal law should require and enforce rigorous age verification for all e-cigarette sales as with the federal PACT (Prevent All Cigarette Trafficking) Act's requirements for age verification in Internet cigarette sales. PMID:25730697

  6. Application of a Near-Field Water Quality Model.

    DTIC Science & Technology

    1979-07-01

    VERIFICATION 45 CENTERLINE TEMPERATURE DECRF~A7F 46 LATERAL VARIATION OF CONSTITUENTS 46 VARIATIOtN OF PLUME WIDTH 49 GENERAL ON VERIFICATION 49...40 4 SOME RESULTS OF VARYING THE ENTRAINMENT COEFFICIENT 4’ 5 RESULTS OF VARYING OTHER COEFFICEINT 42 6 GENERAL PLUME CHARACTERISITICS FOR VARIATION... plume ) axis. These profile forms are then integrated within the basic conservation equations. This integration reduces the problem to a one

  7. Dynamic analysis methods for detecting anomalies in asynchronously interacting systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kumar, Akshat; Solis, John Hector; Matschke, Benjamin

    2014-01-01

    Detecting modifications to digital system designs, whether malicious or benign, is problematic due to the complexity of the systems being analyzed. Moreover, static analysis techniques and tools can only be used during the initial design and implementation phases to verify safety and liveness properties. It is computationally intractable to guarantee that any previously verified properties still hold after a system, or even a single component, has been produced by a third-party manufacturer. In this paper we explore new approaches for creating a robust system design by investigating highly-structured computational models that simplify verification and analysis. Our approach avoids the needmore » to fully reconstruct the implemented system by incorporating a small verification component that dynamically detects for deviations from the design specification at run-time. The first approach encodes information extracted from the original system design algebraically into a verification component. During run-time this component randomly queries the implementation for trace information and verifies that no design-level properties have been violated. If any deviation is detected then a pre-specified fail-safe or notification behavior is triggered. Our second approach utilizes a partitioning methodology to view liveness and safety properties as a distributed decision task and the implementation as a proposed protocol that solves this task. Thus the problem of verifying safety and liveness properties is translated to that of verifying that the implementation solves the associated decision task. We develop upon results from distributed systems and algebraic topology to construct a learning mechanism for verifying safety and liveness properties from samples of run-time executions.« less

  8. PANIC: A General-purpose Panoramic Near-infrared Camera for the Calar Alto Observatory

    NASA Astrophysics Data System (ADS)

    Cárdenas Vázquez, M.-C.; Dorner, B.; Huber, A.; Sánchez-Blanco, E.; Alter, M.; Rodríguez Gómez, J. F.; Bizenberger, P.; Naranjo, V.; Ibáñez Mengual, J.-M.; Panduro, J.; García Segura, A. J.; Mall, U.; Fernández, M.; Laun, W.; Ferro Rodríguez, I. M.; Helmling, J.; Terrón, V.; Meisenheimer, K.; Fried, J. W.; Mathar, R. J.; Baumeister, H.; Rohloff, R.-R.; Storz, C.; Verdes-Montenegro, L.; Bouy, H.; Ubierna, M.; Fopp, P.; Funke, B.

    2018-02-01

    PANIC7 is the new PAnoramic Near-Infrared Camera for Calar Alto and is a project jointly developed by the MPIA in Heidelberg, Germany, and the IAA in Granada, Spain, for the German-Spanish Astronomical Center at Calar Alto Observatory (CAHA; Almería, Spain). This new instrument works with the 2.2 m and 3.5 m CAHA telescopes covering a field of view of 30 × 30 arcmin and 15 × 15 arcmin, respectively, with a sampling of 4096 × 4096 pixels. It is designed for the spectral bands from Z to K S , and can also be equipped with narrowband filters. The instrument was delivered to the observatory in 2014 October and was commissioned at both telescopes between 2014 November and 2015 June. Science verification at the 2.2 m telescope was carried out during the second semester of 2015 and the instrument is now at full operation. We describe the design, assembly, integration, and verification process, the final laboratory tests and the PANIC instrument performance. We also present first-light data obtained during the commissioning and preliminary results of the scientific verification. The final optical model and the theoretical performance of the camera were updated according to the as-built data. The laboratory tests were made with a star simulator. Finally, the commissioning phase was done at both telescopes to validate the camera real performance on sky. The final laboratory test confirmed the expected camera performances, complying with the scientific requirements. The commissioning phase on sky has been accomplished.

  9. A Method for the Evaluation of Thousands of Automated 3D Stem Cell Segmentations

    PubMed Central

    Bajcsy, Peter; Simon, Mylene; Florczyk, Stephen; Simon, Carl G.; Juba, Derek; Brady, Mary

    2016-01-01

    There is no segmentation method that performs perfectly with any data set in comparison to human segmentation. Evaluation procedures for segmentation algorithms become critical for their selection. The problems associated with segmentation performance evaluations and visual verification of segmentation results are exaggerated when dealing with thousands of 3D image volumes because of the amount of computation and manual inputs needed. We address the problem of evaluating 3D segmentation performance when segmentation is applied to thousands of confocal microscopy images (z-stacks). Our approach is to incorporate experimental imaging and geometrical criteria, and map them into computationally efficient segmentation algorithms that can be applied to a very large number of z-stacks. This is an alternative approach to considering existing segmentation methods and evaluating most state-of-the-art algorithms. We designed a methodology for 3D segmentation performance characterization that consists of design, evaluation and verification steps. The characterization integrates manual inputs from projected surrogate “ground truth” of statistically representative samples and from visual inspection into the evaluation. The novelty of the methodology lies in (1) designing candidate segmentation algorithms by mapping imaging and geometrical criteria into algorithmic steps, and constructing plausible segmentation algorithms with respect to the order of algorithmic steps and their parameters, (2) evaluating segmentation accuracy using samples drawn from probability distribution estimates of candidate segmentations, and (3) minimizing human labor needed to create surrogate “truth” by approximating z-stack segmentations with 2D contours from three orthogonal z-stack projections and by developing visual verification tools. We demonstrate the methodology by applying it to a dataset of 1253 mesenchymal stem cells. The cells reside on 10 different types of biomaterial scaffolds, and are stained for actin and nucleus yielding 128 460 image frames (on average 125 cells/scaffold × 10 scaffold types × 2 stains × 51 frames/cell). After constructing and evaluating six candidates of 3D segmentation algorithms, the most accurate 3D segmentation algorithm achieved an average precision of 0.82 and an accuracy of 0.84 as measured by the Dice similarity index where values greater than 0.7 indicate a good spatial overlap. A probability of segmentation success was 0.85 based on visual verification, and a computation time was 42.3 h to process all z-stacks. While the most accurate segmentation technique was 4.2 times slower than the second most accurate algorithm, it consumed on average 9.65 times less memory per z-stack segmentation. PMID:26268699

  10. NASA/BLM APT, phase 2. Volume 2: Technology demonstration. [Arizona

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Techniques described include: (1) steps in the preprocessing of LANDSAT data; (2) the training of a classifier; (3) maximum likelihood classification and precision; (4) geometric correction; (5) class description; (6) digitizing; (7) digital terrain data; (8) an overview of sample design; (9) allocation and selection of primary sample units; (10) interpretation of secondary sample units; (11) data collection ground plots; (12) data reductions; (13) analysis for productivity estimation and map verification; (14) cost analysis; and (150) LANDSAT digital products. The evaluation of the pre-inventory planning for P.J. is included.

  11. Verification Games: Crowd-Sourced Formal Verification

    DTIC Science & Technology

    2016-03-01

    VERIFICATION GAMES : CROWD-SOURCED FORMAL VERIFICATION UNIVERSITY OF WASHINGTON MARCH 2016 FINAL TECHNICAL REPORT...DATES COVERED (From - To) JUN 2012 – SEP 2015 4. TITLE AND SUBTITLE VERIFICATION GAMES : CROWD-SOURCED FORMAL VERIFICATION 5a. CONTRACT NUMBER FA8750...clarification memorandum dated 16 Jan 09. 13. SUPPLEMENTARY NOTES 14. ABSTRACT Over the more than three years of the project Verification Games : Crowd-sourced

  12. NEUTRON MULTIPLICITY AND ACTIVE WELL NEUTRON COINCIDENCE VERIFICATION MEASUREMENTS PERFORMED FOR MARCH 2009 SEMI-ANNUAL DOE INVENTORY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dewberry, R.; Ayers, J.; Tietze, F.

    The Analytical Development (AD) Section field nuclear measurement group performed six 'best available technique' verification measurements to satisfy a DOE requirement instituted for the March 2009 semi-annual inventory. The requirement of (1) yielded the need for SRNL Research Operations Department Material Control & Accountability (MC&A) group to measure the Pu content of five items and the highly enrich uranium (HEU) content of two. No 14Q-qualified measurement equipment was available to satisfy the requirement. The AD field nuclear group has routinely performed the required Confirmatory Measurements for the semi-annual inventories for fifteen years using sodium iodide and high purity germanium (HpGe)more » {gamma}-ray pulse height analysis nondestructive assay (NDA) instruments. With appropriate {gamma}-ray acquisition modeling, the HpGe spectrometers can be used to perform verification-type quantitative assay for Pu-isotopics and HEU content. The AD nuclear NDA group is widely experienced with this type of measurement and reports content for these species in requested process control, MC&A booking, and holdup measurements assays Site-wide. However none of the AD HpGe {gamma}-ray spectrometers have been 14Q-qualified, and the requirement of reference 1 specifically excluded a {gamma}-ray PHA measurement from those it would accept for the required verification measurements. The requirement of reference 1 was a new requirement for which the Savannah River National Laboratory (SRNL) Research Operations Department (ROD) MC&A group was unprepared. The criteria for exemption from verification were: (1) isotope content below 50 grams; (2) intrinsically tamper indicating or TID sealed items which contain a Category IV quantity of material; (3) assembled components; and (4) laboratory samples. Therefore all (SRNL) Material Balance Area (MBA) items with greater than 50 grams total Pu or greater than 50 grams HEU were subject to a verification measurement. The pass/fail criteria of reference 7 stated 'The facility will report measured values, book values, and statistical control limits for the selected items to DOE SR...', and 'The site/facility operator must develop, document, and maintain measurement methods for all nuclear material on inventory'. These new requirements exceeded SRNL's experience with prior semi-annual inventory expectations, but allowed the AD nuclear field measurement group to demonstrate its excellent adaptability and superior flexibility to respond to unpredicted expectations from the DOE customer. The requirements yielded five SRNL items subject to Pu verification and two SRNL items subject to HEU verification. These items are listed and described in Table 1.« less

  13. 29 CFR 1903.19 - Abatement verification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... identify the violation and the steps to be taken to achieve abatement, including a schedule for completing..., the progress report must identify, in a single sentence if possible, the action taken to achieve abatement and the date the action was taken. Note to paragraph (f): Appendix B contains a Sample Progress...

  14. 23 CFR 637.205 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    .... Each STD shall develop a quality assurance program which will assure that the materials and workmanship... criteria in § 637.207 and be approved by the FHWA. (b) STD capabilities. The STD shall maintain an adequate... qualified sampling and testing personnel employed by the STD or its designated agent. (d) Verification...

  15. 23 CFR 637.205 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... Each STD shall develop a quality assurance program which will assure that the materials and workmanship... criteria in § 637.207 and be approved by the FHWA. (b) STD capabilities. The STD shall maintain an adequate... qualified sampling and testing personnel employed by the STD or its designated agent. (d) Verification...

  16. 23 CFR 637.205 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... Each STD shall develop a quality assurance program which will assure that the materials and workmanship... criteria in § 637.207 and be approved by the FHWA. (b) STD capabilities. The STD shall maintain an adequate... qualified sampling and testing personnel employed by the STD or its designated agent. (d) Verification...

  17. 23 CFR 637.205 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... Each STD shall develop a quality assurance program which will assure that the materials and workmanship... criteria in § 637.207 and be approved by the FHWA. (b) STD capabilities. The STD shall maintain an adequate... qualified sampling and testing personnel employed by the STD or its designated agent. (d) Verification...

  18. 23 CFR 637.205 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... Each STD shall develop a quality assurance program which will assure that the materials and workmanship... criteria in § 637.207 and be approved by the FHWA. (b) STD capabilities. The STD shall maintain an adequate... qualified sampling and testing personnel employed by the STD or its designated agent. (d) Verification...

  19. 77 FR 9888 - Shiga Toxin-Producing Escherichia coli

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-21

    ... Toxin-Producing Escherichia coli in Certain Raw Beef Products AGENCY: Food Safety and Inspection Service... routine verification sampling and testing for raw beef manufacturing trimmings for six non-O157 Shiga... announced in September 2011 plans to test certain raw beef products for these six STEC serogroups in...

  20. AERIAL PHOTOGRAPHY AND GROUND VERIFICATION AT POWER PLANT SITES: WISCONSIN POWER PLANT IMPACT STUDY

    EPA Science Inventory

    This study demonstrated and evaluated nine methods for monitoring the deterioration of a large wetland on the site of a newly-constructed coal-fired power plant in Columbia, County, Wisconsin. Four of the nine methods used data from ground sampling; two were remote sensing method...

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