Sample records for versatile portable speech

  1. Research and development of a versatile portable speech prosthesis

    NASA Technical Reports Server (NTRS)

    1981-01-01

    The Versatile Portable Speech Prosthesis (VPSP), a synthetic speech output communication aid for non-speaking people is described. It was intended initially for severely physically limited people with cerebral palsy who are in electric wheelchairs. Hence, it was designed to be placed on a wheelchair and powered from a wheelchair battery. It can easily be separated from the wheelchair. The VPSP is versatile because it is designed to accept any means of single switch, multiple switch, or keyboard control which physically limited people have the ability to use. It is portable because it is mounted on and can go with the electric wheelchair. It is a speech prosthesis, obviously, because it speaks with a synthetic voice for people unable to speak with their own voices. Both hardware and software are described.

  2. The feasibility of miniaturizing the versatile portable speech prosthesis: A market survey of commercial products

    NASA Technical Reports Server (NTRS)

    Walklet, T.

    1981-01-01

    The feasibility of a miniature versatile portable speech prosthesis (VPSP) was analyzed and information on its potential users and on other similar devices was collected. The VPSP is a device that incorporates speech synthesis technology. The objective is to provide sufficient information to decide whether there is valuable technology to contribute to the miniaturization of the VPSP. The needs of potential users are identified, the development status of technologies similar or related to those used in the VPSP are evaluated. The VPSP, a computer based speech synthesis system fits on a wheelchair. The purpose was to produce a device that provides communication assistance in educational, vocational, and social situations to speech impaired individuals. It is expected that the VPSP can be a valuable aid for persons who are also motor impaired, which explains the placement of the system on a wheelchair.

  3. Biomedical technology transfer. Applications of NASA science and technology

    NASA Technical Reports Server (NTRS)

    Harrison, D. C.

    1980-01-01

    Ongoing projects described address: (1) intracranial pressure monitoring; (2) versatile portable speech prosthesis; (3) cardiovascular magnetic measurements; (4) improved EMG biotelemetry for pediatrics; (5) ultrasonic kidney stone disintegration; (6) pediatric roentgen densitometry; (7) X-ray spatial frequency multiplexing; (8) mechanical impedance determination of bone strength; (9) visual-to-tactile mobility aid for the blind; (10) Purkinje image eyetracker and stabilized photocoalqulator; (11) neurological applications of NASA-SRI eyetracker; (12) ICU synthesized speech alarm; (13) NANOPHOR: microelectrophoresis instrument; (14) WRISTCOM: tactile communication system for the deaf-blind; (15) medical applications of NASA liquid-circulating garments; and (16) hip prosthesis with biotelemetry. Potential transfer projects include a person-portable versatile speech prosthesis, a critical care transport sytem, a clinical information system for cardiology, a programmable biofeedback orthosis for scoliosis a pediatric long-bone reconstruction, and spinal immobilization apparatus.

  4. Design and Evaluation of a Personal Digital Assistant-based Research Platform for Cochlear Implants

    PubMed Central

    Ali, Hussnain; Lobo, Arthur P.; Loizou, Philipos C.

    2014-01-01

    This paper discusses the design, development, features, and clinical evaluation of a personal digital assistant (PDA)-based platform for cochlear implant research. This highly versatile and portable research platform allows researchers to design and perform complex experiments with cochlear implants manufactured by Cochlear Corporation with great ease and flexibility. The research platform includes a portable processor for implementing and evaluating novel speech processing algorithms, a stimulator unit which can be used for electrical stimulation and neurophysio-logic studies with animals, and a recording unit for collecting electroencephalogram/evoked potentials from human subjects. The design of the platform for real time and offline stimulation modes is discussed for electric-only and electric plus acoustic stimulation followed by results from an acute study with implant users for speech intelligibility in quiet and noisy conditions. The results are comparable with users’ clinical processor and very promising for undertaking chronic studies. PMID:23674422

  5. Talking Wheelchair

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Communication is made possible for disabled individuals by means of an electronic system, developed at Stanford University's School of Medicine, which produces highly intelligible synthesized speech. Familiarly known as the "talking wheelchair" and formally as the Versatile Portable Speech Prosthesis (VPSP). Wheelchair mounted system consists of a word processor, a video screen, a voice synthesizer and a computer program which instructs the synthesizer how to produce intelligible sounds in response to user commands. Computer's memory contains 925 words plus a number of common phrases and questions. Memory can also store several thousand other words of the user's choice. Message units are selected by operating a simple switch, joystick or keyboard. Completed message appears on the video screen, then user activates speech synthesizer, which generates a voice with a somewhat mechanical tone. With the keyboard, an experienced user can construct messages as rapidly as 30 words per minute.

  6. Versatile simulation testbed for rotorcraft speech I/O system design

    NASA Technical Reports Server (NTRS)

    Simpson, Carol A.

    1986-01-01

    A versatile simulation testbed for the design of a rotorcraft speech I/O system is described in detail. The testbed will be used to evaluate alternative implementations of synthesized speech displays and speech recognition controls for the next generation of Army helicopters including the LHX. The message delivery logic is discussed as well as the message structure, the speech recognizer command structure and features, feedback from the recognizer, and random access to controls via speech command.

  7. A Systematic Review of Tablet Computers and Portable Media Players as Speech Generating Devices for Individuals with Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Lorah, Elizabeth R.; Parnell, Ashley; Whitby, Peggy Schaefer; Hantula, Donald

    2015-01-01

    Powerful, portable, off-the-shelf handheld devices, such as tablet based computers (i.e., iPad®; Galaxy®) or portable multimedia players (i.e., iPod®), can be adapted to function as speech generating devices for individuals with autism spectrum disorders or related developmental disabilities. This paper reviews the research in this new and rapidly…

  8. Development of a Low-Cost, Noninvasive, Portable Visual Speech Recognition Program.

    PubMed

    Kohlberg, Gavriel D; Gal, Ya'akov Kobi; Lalwani, Anil K

    2016-09-01

    Loss of speech following tracheostomy and laryngectomy severely limits communication to simple gestures and facial expressions that are largely ineffective. To facilitate communication in these patients, we seek to develop a low-cost, noninvasive, portable, and simple visual speech recognition program (VSRP) to convert articulatory facial movements into speech. A Microsoft Kinect-based VSRP was developed to capture spatial coordinates of lip movements and translate them into speech. The articulatory speech movements associated with 12 sentences were used to train an artificial neural network classifier. The accuracy of the classifier was then evaluated on a separate, previously unseen set of articulatory speech movements. The VSRP was successfully implemented and tested in 5 subjects. It achieved an accuracy rate of 77.2% (65.0%-87.6% for the 5 speakers) on a 12-sentence data set. The mean time to classify an individual sentence was 2.03 milliseconds (1.91-2.16). We have demonstrated the feasibility of a low-cost, noninvasive, portable VSRP based on Kinect to accurately predict speech from articulation movements in clinically trivial time. This VSRP could be used as a novel communication device for aphonic patients. © The Author(s) 2016.

  9. Health Insurance Portability and Accountability Act (HIPAA) legislation and its implication on speech privacy design in health care facilities

    NASA Astrophysics Data System (ADS)

    Tocci, Gregory C.; Storch, Christopher A.

    2005-09-01

    The Health Insurance Portability and Accountability Act (HIPAA) of 1996 (104th Congress, H.R. 3103, January 3, 1986), among many things, individual patient records and information be protected from unnecessary issue. This responsibility is assigned to the U.S. Department of Health and Human Services (HHS) which has issued a Privacy Rule most recently dated August 2002 with a revision being proposed in 2005 to strengthen penalties for inappropriate breaches of patient privacy. Despite this, speech privacy, in many instances in health care facilities need not be guaranteed by the facility. Nevertheless, the regulation implies that due regard be given to speech privacy in both facility design and operation. This presentation will explore the practical aspects of implementing speech privacy in health care facilities and make recommendations for certain specific speech privacy situations.

  10. A portable vacuum for collecting arthropods from drop cloths.

    Treesearch

    H.G. Paul; R.R. Mason

    1985-01-01

    A hand-held vacuum modified for collecting insects and spiders in the field is described. The vacuum with battery is mounted on a lightweight pack-frame and is portable and versatile. It is especially useful for collecting arthropods that are dislodged from foliage samples and drop onto cloths.

  11. A semi-automated, field-portable microscopy platform for clinical diagnostic applications

    NASA Astrophysics Data System (ADS)

    Jagannadh, Veerendra Kalyan; Srinivasan, Rajesh; Gorthi, Sai Siva

    2015-08-01

    Clinical microscopy is a versatile diagnostic platform used for diagnosis of a multitude of diseases. In the recent past, many microfluidics based point-of-care diagnostic devices have been developed, which serve as alternatives to microscopy. However, these point-of-care devices are not as multi-functional and versatile as clinical microscopy. With the use of custom designed optics and microfluidics, we have developed a versatile microscopy-based cellular diagnostic platform, which can be used at the point of care. The microscopy platform presented here is capable of detecting infections of very low parasitemia level (in a very small quantity of sample), without the use of any additional computational hardware. Such a cost-effective and portable diagnostic device, would greatly impact the quality of health care available to people living in rural locations of the world. Apart from clinical diagnostics, it's applicability to field research in environmental microbiology has also been outlined.

  12. Versatile Desktop Experiment Module (DEMo) on Heat Transfer

    ERIC Educational Resources Information Center

    Minerick, Adrienne R.

    2010-01-01

    This paper outlines a new Desktop Experiment Module (DEMo) engineered for a chemical engineering junior-level Heat Transfer course. This new DEMo learning tool is versatile, fairly inexpensive, and portable such that it can be positioned on student desks throughout a classroom. The DEMo system can illustrate conduction of various materials,…

  13. A Portable, High Resolution, Surface Measurement Device

    NASA Technical Reports Server (NTRS)

    Ihlefeld, Curtis M.; Burns, Bradley M.; Youngquist, Robert C.

    2012-01-01

    A high resolution, portable, surface measurement device has been demonstrated to provide micron-resolution topographical plots. This device was specifically developed to allow in-situ measurements of defects on the Space Shuttle Orbiter windows, but is versatile enough to be used on a wide variety of surfaces. This paper discusses the choice of an optical sensor and then the decisions required to convert a lab bench optical measurement device into an ergonomic portable system. The necessary trade-offs between performance and portability are presented along with a description of the device developed to measure Orbiter window defects.

  14. Novel versatile smart phone based Microplate readers for on-site diagnoses.

    PubMed

    Fu, Qiangqiang; Wu, Ze; Li, Xiuqing; Yao, Cuize; Yu, Shiting; Xiao, Wei; Tang, Yong

    2016-07-15

    Microplate readers are important diagnostic instruments, used intensively for various readout test kits (biochemical analysis kits and ELISA kits). However, due to their expensive and non-portability, commercial microplate readers are unavailable for home testing, community and rural hospitals, especially in developing countries. In this study, to provide a field-portable, cost-effective and versatile diagnostic tool, we reported a novel smart phone based microplate reader. The basic principle of this devise relies on a smart phone's optical sensor that measures transmitted light intensities of liquid samples. To prove the validity of these devises, developed smart phone based microplate readers were applied to readout results of various analytical targets. These targets included analanine aminotransferase (ALT; limit of detection (LOD) was 17.54 U/L), alkaline phosphatase (AKP; LOD was 15.56 U/L), creatinine (LOD was 1.35μM), bovine serum albumin (BSA; LOD was 0.0041mg/mL), prostate specific antigen (PSA; LOD was 0.76pg/mL), and ractopamine (Rac; LOD was 0.31ng/mL). The developed smart phone based microplate readers are versatile, portable, and inexpensive; they are unique because of their ability to perform under circumstances where resources and expertize are limited. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. A Systematic Review of Tablet Computers and Portable Media Players as Speech Generating Devices for Individuals with Autism Spectrum Disorder.

    PubMed

    Lorah, Elizabeth R; Parnell, Ashley; Whitby, Peggy Schaefer; Hantula, Donald

    2015-12-01

    Powerful, portable, off-the-shelf handheld devices, such as tablet based computers (i.e., iPad(®); Galaxy(®)) or portable multimedia players (i.e., iPod(®)), can be adapted to function as speech generating devices for individuals with autism spectrum disorders or related developmental disabilities. This paper reviews the research in this new and rapidly growing area and delineates an agenda for future investigations. In general, participants using these devices acquired verbal repertoires quickly. Studies comparing these devices to picture exchange or manual sign language found that acquisition was often quicker when using a tablet computer and that the vast majority of participants preferred using the device to picture exchange or manual sign language. Future research in interface design, user experience, and extended verbal repertoires is recommended.

  16. Portable Speech Synthesizer

    NASA Technical Reports Server (NTRS)

    Leibfritz, Gilbert H.; Larson, Howard K.

    1987-01-01

    Compact speech synthesizer useful traveling companion to speech-handicapped. User simply enters statement on board, and synthesizer converts statement into spoken words. Battery-powered and housed in briefcase, easily carried on trips. Unit used on telephones and face-to-face communication. Synthesizer consists of micro-computer with memory-expansion module, speech-synthesizer circuit, batteries, recharger, dc-to-dc converter, and telephone amplifier. Components, commercially available, fit neatly in 17-by 13-by 5-in. briefcase. Weighs about 20 lb (9 kg) and operates and recharges from ac receptable.

  17. A portable smoking pattern recorder.

    PubMed

    Creighton, D E; Noble, M J; Whewell, R T

    1979-01-01

    An instrument has been developed which can be used to record the smoking patterns of human smokers in almost any location. The smoker is required to smoke the cigarette through an orifice plate cigarette holder connected to the recorder. The smoking pattern data are recorded onto a standard audio cassette as pressure and flow signals together with timing impulses and speech. The instrument is battery powered and can be built into a small brief case. The four channels of data are decoded on a separate instrument, which uses the timing signals to synchronise a data logger, thus making the whole system independent of tape speed errors. The speech channel is used to identify the smoker, cigarette, location, etc. Comparisons have been made of the performance of the portable recorder and a laboratory smoking analyser and data logger. It was found that data decoded from the portable recorder are generally within 1% of the values recorded directly on the laboratory instrument.

  18. Telephone Communication for the Deaf: Speech Indicator Manual.

    ERIC Educational Resources Information Center

    Jones, Ray L.

    The instructional manual is designed to accompany the Speech Indicator, a small, portable, economical ($15) device for deaf persons for telephone communication (available from Leadership Training Program in the Area of the Deaf, San Fernando State College). The device indicates when the other party speaks, not what he says. A topic outline and…

  19. Digital Remix

    ERIC Educational Resources Information Center

    Roach, Ronald

    2010-01-01

    There's no doubt laptop programs remain important to many institutions, particularly to those that consider social equity an important value in their technology programs. Now, the transition to mobile computing, which puts smaller and often more versatile portable devices in the marketplace, has inspired college and university administrators to…

  20. Joint Spatial-Spectral Feature Space Clustering for Speech Activity Detection from ECoG Signals

    PubMed Central

    Kanas, Vasileios G.; Mporas, Iosif; Benz, Heather L.; Sgarbas, Kyriakos N.; Bezerianos, Anastasios; Crone, Nathan E.

    2014-01-01

    Brain machine interfaces for speech restoration have been extensively studied for more than two decades. The success of such a system will depend in part on selecting the best brain recording sites and signal features corresponding to speech production. The purpose of this study was to detect speech activity automatically from electrocorticographic signals based on joint spatial-frequency clustering of the ECoG feature space. For this study, the ECoG signals were recorded while a subject performed two different syllable repetition tasks. We found that the optimal frequency resolution to detect speech activity from ECoG signals was 8 Hz, achieving 98.8% accuracy by employing support vector machines (SVM) as a classifier. We also defined the cortical areas that held the most information about the discrimination of speech and non-speech time intervals. Additionally, the results shed light on the distinct cortical areas associated with the two syllable repetition tasks and may contribute to the development of portable ECoG-based communication. PMID:24658248

  1. 42 CFR 498.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) Independent diagnostic testing facility. (5) Physician or other practitioner such as physician assistant. (6) Physical therapist in independent practice. (7) Supplier of portable X-ray services. (8) Rural health... only to furnish outpatient physical therapy or outpatient speech pathology services. (i) Clinic. (ii...

  2. 42 CFR 498.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) Independent diagnostic testing facility. (5) Physician or other practitioner such as physician assistant. (6) Physical therapist in independent practice. (7) Supplier of portable X-ray services. (8) Rural health... only to furnish outpatient physical therapy or outpatient speech pathology services. (i) Clinic. (ii...

  3. 42 CFR 498.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Independent diagnostic testing facility. (5) Physician or other practitioner such as physician assistant. (6) Physical therapist in independent practice. (7) Supplier of portable X-ray services. (8) Rural health... only to furnish outpatient physical therapy or outpatient speech pathology services. (i) Clinic. (ii...

  4. 42 CFR 498.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) Independent diagnostic testing facility. (5) Physician or other practitioner such as physician assistant. (6) Physical therapist in independent practice. (7) Supplier of portable X-ray services. (8) Rural health... only to furnish outpatient physical therapy or outpatient speech pathology services. (i) Clinic. (ii...

  5. Smart portable rehabilitation devices.

    PubMed

    Mavroidis, Constantinos; Nikitczuk, Jason; Weinberg, Brian; Danaher, Gil; Jensen, Katherine; Pelletier, Philip; Prugnarola, Jennifer; Stuart, Ryan; Arango, Roberto; Leahey, Matt; Pavone, Robert; Provo, Andrew; Yasevac, Dan

    2005-07-12

    The majority of current portable orthotic devices and rehabilitative braces provide stability, apply precise pressure, or help maintain alignment of the joints with out the capability for real time monitoring of the patient's motions and forces and without the ability for real time adjustments of the applied forces and motions. Improved technology has allowed for advancements where these devices can be designed to apply a form of tension to resist motion of the joint. These devices induce quicker recovery and are more effective at restoring proper biomechanics and improving muscle function. However, their shortcoming is in their inability to be adjusted in real-time, which is the most ideal form of a device for rehabilitation. This introduces a second class of devices beyond passive orthotics. It is comprised of "active" or powered devices, and although more complicated in design, they are definitely the most versatile. An active or powered orthotic, usually employs some type of actuator(s). In this paper we present several new advancements in the area of smart rehabilitation devices that have been developed by the Northeastern University Robotics and Mechatronics Laboratory. They are all compact, wearable and portable devices and boast re-programmable, real time computer controlled functions as the central theme behind their operation. The sensory information and computer control of the three described devices make for highly efficient and versatile systems that represent a whole new breed in wearable rehabilitation devices. Their applications range from active-assistive rehabilitation to resistance exercise and even have applications in gait training. The three devices described are: a transportable continuous passive motion elbow device, a wearable electro-rheological fluid based knee resistance device, and a wearable electrical stimulation and biofeedback knee device. Laboratory tests of the devices demonstrated that they were able to meet their design objectives. The prototypes of portable rehabilitation devices presented here did demonstrate that these concepts are capable of the performance their commercially available but non-portable counterparts exhibit. Smart, portable devices with the ability for real time monitoring and adjustment open a new era in rehabilitation where the recovery process could be dramatically improved.

  6. Smart portable rehabilitation devices

    PubMed Central

    Mavroidis, Constantinos; Nikitczuk, Jason; Weinberg, Brian; Danaher, Gil; Jensen, Katherine; Pelletier, Philip; Prugnarola, Jennifer; Stuart, Ryan; Arango, Roberto; Leahey, Matt; Pavone, Robert; Provo, Andrew; Yasevac, Dan

    2005-01-01

    Background The majority of current portable orthotic devices and rehabilitative braces provide stability, apply precise pressure, or help maintain alignment of the joints with out the capability for real time monitoring of the patient's motions and forces and without the ability for real time adjustments of the applied forces and motions. Improved technology has allowed for advancements where these devices can be designed to apply a form of tension to resist motion of the joint. These devices induce quicker recovery and are more effective at restoring proper biomechanics and improving muscle function. However, their shortcoming is in their inability to be adjusted in real-time, which is the most ideal form of a device for rehabilitation. This introduces a second class of devices beyond passive orthotics. It is comprised of "active" or powered devices, and although more complicated in design, they are definitely the most versatile. An active or powered orthotic, usually employs some type of actuator(s). Methods In this paper we present several new advancements in the area of smart rehabilitation devices that have been developed by the Northeastern University Robotics and Mechatronics Laboratory. They are all compact, wearable and portable devices and boast re-programmable, real time computer controlled functions as the central theme behind their operation. The sensory information and computer control of the three described devices make for highly efficient and versatile systems that represent a whole new breed in wearable rehabilitation devices. Their applications range from active-assistive rehabilitation to resistance exercise and even have applications in gait training. The three devices described are: a transportable continuous passive motion elbow device, a wearable electro-rheological fluid based knee resistance device, and a wearable electrical stimulation and biofeedback knee device. Results Laboratory tests of the devices demonstrated that they were able to meet their design objectives. The prototypes of portable rehabilitation devices presented here did demonstrate that these concepts are capable of the performance their commercially available but non-portable counterparts exhibit. Conclusion Smart, portable devices with the ability for real time monitoring and adjustment open a new era in rehabilitation where the recovery process could be dramatically improved. PMID:16011801

  7. An inexpensive compact automatic camera system for wildlife research

    Treesearch

    William R. Danielson; Richard M. DeGraaf; Todd K. Fuller

    1996-01-01

    This paper describes the design, conversion, and deployment of a reliable, compact, automatic multiple-exposure photographic system that was used to photograph nest predation events. This system may be the most versatile yet described in the literature because of its simplicity, portability, and dependability. The system was very reliable because it was designed around...

  8. Women and Private Pensions.

    ERIC Educational Resources Information Center

    Benson, Helene A.

    This speech focuses on women and private pension plans, such as private pension coverage and smaller benefit amounts. Pension issues affecting women as employees include participation in plans, vesting, break-in service, benefit accruals, integration with Social Security, sex-based actuarial tables, portability, inflation, and individual…

  9. A portable mid-range localization system using infrared LEDs for visually impaired people

    NASA Astrophysics Data System (ADS)

    Park, Suhyeon; Choi, In-Mook; Kim, Sang-Soo; Kim, Sung-Mok

    2014-11-01

    A versatile indoor/outdoor pedestrian guidance system with good mobility is necessary in order to aid visually impaired pedestrians in indoor and outdoor environments. In this paper, distance estimation methods for portable wireless localization systems are verified. Two systems of a fixed active beacon and a receiver using an ultrasound time-of-flight method and a differential infrared intensity method are proposed. The infrared localization system was appropriate for the goal of this study. It was possible to use the infrared intensity method to generate a uniform signal field that exceeded 30 m. Valid distance estimations which were within 30 m of coverage indoors and within 20 m of coverage outdoors were made. Also, a pocket-sized receiver which can be adapted to a smartphone was found to be suitable for use as a portable device.

  10. Input Devices for Young Handicapped Children.

    ERIC Educational Resources Information Center

    Morris, Karen

    The versatility of the computer can be expanded considerably for young handicapped children by using input devices other than the typewriter-style keyboard. Input devices appropriate for young children can be classified into four categories: alternative keyboards, contact switches, speech input devices, and cursor control devices. Described are…

  11. Time-Varying Vocal Folds Vibration Detection Using a 24 GHz Portable Auditory Radar

    PubMed Central

    Hong, Hong; Zhao, Heng; Peng, Zhengyu; Li, Hui; Gu, Chen; Li, Changzhi; Zhu, Xiaohua

    2016-01-01

    Time-varying vocal folds vibration information is of crucial importance in speech processing, and the traditional devices to acquire speech signals are easily smeared by the high background noise and voice interference. In this paper, we present a non-acoustic way to capture the human vocal folds vibration using a 24-GHz portable auditory radar. Since the vocal folds vibration only reaches several millimeters, the high operating frequency and the 4 × 4 array antennas are applied to achieve the high sensitivity. The Variational Mode Decomposition (VMD) based algorithm is proposed to decompose the radar-detected auditory signal into a sequence of intrinsic modes firstly, and then, extract the time-varying vocal folds vibration frequency from the corresponding mode. Feasibility demonstration, evaluation, and comparison are conducted with tonal and non-tonal languages, and the low relative errors show a high consistency between the radar-detected auditory time-varying vocal folds vibration and acoustic fundamental frequency, except that the auditory radar significantly improves the frequency-resolving power. PMID:27483261

  12. Time-Varying Vocal Folds Vibration Detection Using a 24 GHz Portable Auditory Radar.

    PubMed

    Hong, Hong; Zhao, Heng; Peng, Zhengyu; Li, Hui; Gu, Chen; Li, Changzhi; Zhu, Xiaohua

    2016-07-28

    Time-varying vocal folds vibration information is of crucial importance in speech processing, and the traditional devices to acquire speech signals are easily smeared by the high background noise and voice interference. In this paper, we present a non-acoustic way to capture the human vocal folds vibration using a 24-GHz portable auditory radar. Since the vocal folds vibration only reaches several millimeters, the high operating frequency and the 4 × 4 array antennas are applied to achieve the high sensitivity. The Variational Mode Decomposition (VMD) based algorithm is proposed to decompose the radar-detected auditory signal into a sequence of intrinsic modes firstly, and then, extract the time-varying vocal folds vibration frequency from the corresponding mode. Feasibility demonstration, evaluation, and comparison are conducted with tonal and non-tonal languages, and the low relative errors show a high consistency between the radar-detected auditory time-varying vocal folds vibration and acoustic fundamental frequency, except that the auditory radar significantly improves the frequency-resolving power.

  13. A multimedia PDA/PC speech and language therapy tool for patients with aphasia.

    PubMed

    Reeves, Nina; Jefferies, Laura; Cunningham, Sally-Jo; Harris, Catherine

    2007-01-01

    Aphasia is a speech disorder usually caused by stroke or head injury and may involve a variety of communication difficulties. As 30% of stroke sufferers have a persisting speech and language disorder and therapy resources are low, there is clear scope for the development of technology to support patients between therapy sessions. This paper reports on an empirical study which evaluated SoundHelper, a multimedia application to demonstrate how to pronounce target speech sounds. Two prototypes, involving either video or animation, were developed and evaluated with 20 Speech and Language Therapists. Participants responded positively to both, with the video being preferred because of the perceived extra information provided. The potential for the use on portable devices, since internet access is limited in hospitals, is explored in the light of opinions of Augmented and Alternative Communication (AAC) device users in the UK nd Europe who have expressed a strong desire for more use of internet services.

  14. Applications of Microcomputers in the Education of the Physically Disabled Child.

    ERIC Educational Resources Information Center

    Foulds, Richard A.

    1982-01-01

    Microcomputers can serve as expressive communication tools for severely physically disabled persons. Features such as single input devices, direct selection aids, and speech synthesis capabilities can be extremely useful. The trend toward portable battery-operated computers will make the technology even more accessible. (CL)

  15. Use of Videorecording Equipment as an Educational Tool.

    ERIC Educational Resources Information Center

    Webster, Harold J.

    The faculty at the DuBois Campus of the Pennsylvania State University are using video recording equipment in a variety of ways. Student performances are videotaped for different purposes in speech, marketing, and physical education classes. Professors in the Wildlife Technology Program are using portable videotaping equipment to record activities…

  16. Rapidly deployable emergency communication system

    DOEpatents

    Gladden, Charles A.; Parelman, Martin H.

    1979-01-01

    A highly versatile, highly portable emergency communication system which permits deployment in a very short time to cover both wide areas and distant isolated areas depending upon mission requirements. The system employs a plurality of lightweight, fully self-contained repeaters which are deployed within the mission area to provide communication between field teams, and between each field team and a mobile communication control center. Each repeater contains a microcomputer controller, the program for which may be changed from the control center by the transmission of digital data within the audible range (300-3,000 Hz). Repeaters are accessed by portable/mobile transceivers, other repeaters, and the control center through the transmission and recognition of digital data code words in the subaudible range.

  17. Military and Government Applications of Human-Machine Communication by Voice

    NASA Astrophysics Data System (ADS)

    Weinstein, Clifford J.

    1995-10-01

    This paper describes a range of opportunities for military and government applications of human-machine communication by voice, based on visits and contacts with numerous user organizations in the United States. The applications include some that appear to be feasible by careful integration of current state-of-the-art technology and others that will require a varying mix of advances in speech technology and in integration of the technology into applications environments. Applications that are described include (1) speech recognition and synthesis for mobile command and control; (2) speech processing for a portable multifunction soldier's computer; (3) speech- and language-based technology for naval combat team tactical training; (4) speech technology for command and control on a carrier flight deck; (5) control of auxiliary systems, and alert and warning generation, in fighter aircraft and helicopters; and (6) voice check-in, report entry, and communication for law enforcement agents or special forces. A phased approach for transfer of the technology into applications is advocated, where integration of applications systems is pursued in parallel with advanced research to meet future needs.

  18. Simulating Scenes In Outer Space

    NASA Technical Reports Server (NTRS)

    Callahan, John D.

    1989-01-01

    Multimission Interactive Picture Planner, MIP, computer program for scientifically accurate and fast, three-dimensional animation of scenes in deep space. Versatile, reasonably comprehensive, and portable, and runs on microcomputers. New techniques developed to perform rapidly calculations and transformations necessary to animate scenes in scientifically accurate three-dimensional space. Written in FORTRAN 77 code. Primarily designed to handle Voyager, Galileo, and Space Telescope. Adapted to handle other missions.

  19. UDAF bioenvironmental noise data handbook. Volume 164: MD-1 heater, duct type, portable

    NASA Astrophysics Data System (ADS)

    Rau, T. H.

    1982-05-01

    The MD-1 heater is an electric motor-driven, portable ground heater used primarily for cockpit and cabin temperature control. This report provides measured and extrapolated data defining the bioacoustic environments produced by this unit operating outdoors on a concrete apron at normal rated conditions. Near-field data are reported for 37 locations in a wide variety of physical and psychoacoustic measures: overall and band sound pressure levels, C-weighted and A-weighted sound levels, preferred speech interference level, perceived noise levels, and limiting times for total daily exposure of personnel with and without standard Air Force ear protectors.

  20. A Smartphone Application for Customized Frequency Table Selection in Cochlear Implants.

    PubMed

    Jethanamest, Daniel; Azadpour, Mahan; Zeman, Annette M; Sagi, Elad; Svirsky, Mario A

    2017-09-01

    A novel smartphone-based software application can facilitate self-selection of frequency allocation tables (FAT) in postlingually deaf cochlear implant (CI) users. CIs use FATs to represent the tonotopic organization of a normal cochlea. Current CI fitting methods typically use a standard FAT for all patients regardless of individual differences in cochlear size and electrode location. In postlingually deaf patients, different amounts of mismatch can result between the frequency-place function they experienced when they had normal hearing and the frequency-place function that results from the standard FAT. For some CI users, an alternative FAT may enhance sound quality or speech perception. Currently, no widely available tools exist to aid real-time selection of different FATs. This study aims to develop a new smartphone tool for this purpose and to evaluate speech perception and sound quality measures in a pilot study of CI subjects using this application. A smartphone application for a widely available mobile platform (iOS) was developed to serve as a preprocessor of auditory input to a clinical CI speech processor and enable interactive real-time selection of FATs. The application's output was validated by measuring electrodograms for various inputs. A pilot study was conducted in six CI subjects. Speech perception was evaluated using word recognition tests. All subjects successfully used the portable application with their clinical speech processors to experience different FATs while listening to running speech. The users were all able to select one table that they judged provided the best sound quality. All subjects chose a FAT different from the standard FAT in their everyday clinical processor. Using the smartphone application, the mean consonant-nucleus-consonant score with the default FAT selection was 28.5% (SD 16.8) and 29.5% (SD 16.4) when using a self-selected FAT. A portable smartphone application enables CI users to self-select frequency allocation tables in real time. Even though the self-selected FATs that were deemed to have better sound quality were only tested acutely (i.e., without long-term experience with them), speech perception scores were not inferior to those obtained with the clinical FATs. This software application may be a valuable tool for improving future methods of CI fitting.

  1. The Compensatory Effectiveness of the Quicktionary Reading Pen II on the Reading Comprehension of Students with Learning Disabilities

    ERIC Educational Resources Information Center

    Higgins, Eleanor L.; Raskind, Marshall H.

    2005-01-01

    The study investigated the compensatory effectiveness of the Quicktionary Reading Pen II (the Reading Pen), a portable device with miniaturized optical character recognition and speech synthesis capabilities. Thirty participants with reading disabilities aged 10-18 were trained on the operation of the technology and given two weeks to practice…

  2. Military and government applications of human-machine communication by voice.

    PubMed Central

    Weinstein, C J

    1995-01-01

    This paper describes a range of opportunities for military and government applications of human-machine communication by voice, based on visits and contacts with numerous user organizations in the United States. The applications include some that appear to be feasible by careful integration of current state-of-the-art technology and others that will require a varying mix of advances in speech technology and in integration of the technology into applications environments. Applications that are described include (1) speech recognition and synthesis for mobile command and control; (2) speech processing for a portable multifunction soldier's computer; (3) speech- and language-based technology for naval combat team tactical training; (4) speech technology for command and control on a carrier flight deck; (5) control of auxiliary systems, and alert and warning generation, in fighter aircraft and helicopters; and (6) voice check-in, report entry, and communication for law enforcement agents or special forces. A phased approach for transfer of the technology into applications is advocated, where integration of applications systems is pursued in parallel with advanced research to meet future needs. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 PMID:7479718

  3. Dialogue enabling speech-to-text user assistive agent system for hearing-impaired person.

    PubMed

    Lee, Seongjae; Kang, Sunmee; Han, David K; Ko, Hanseok

    2016-06-01

    A novel approach for assisting bidirectional communication between people of normal hearing and hearing-impaired is presented. While the existing hearing-impaired assistive devices such as hearing aids and cochlear implants are vulnerable in extreme noise conditions or post-surgery side effects, the proposed concept is an alternative approach wherein spoken dialogue is achieved by means of employing a robust speech recognition technique which takes into consideration of noisy environmental factors without any attachment into human body. The proposed system is a portable device with an acoustic beamformer for directional noise reduction and capable of performing speech-to-text transcription function, which adopts a keyword spotting method. It is also equipped with an optimized user interface for hearing-impaired people, rendering intuitive and natural device usage with diverse domain contexts. The relevant experimental results confirm that the proposed interface design is feasible for realizing an effective and efficient intelligent agent for hearing-impaired.

  4. Infrared Fourier spectrometer for laboratory use and for astronomical studies from aircraft and ground-based telescopes

    NASA Technical Reports Server (NTRS)

    Larson, H. P.; Fink, U.

    1975-01-01

    A portable, versatile, IR Fourier spectrometer is described that provides 0.5 per cm spectral resolution in the 0.87-5.6-micron region. This spectrometer is employed in a varied program of astronomical observations from ground-based telescopes and from the NASA 91.5-cm airborne IR telescope. A number of spectral results are presented to illustrate the performance of this spectrometer in astronomical applications.

  5. Low Level Leaks

    NASA Technical Reports Server (NTRS)

    1998-01-01

    NASA has transferred the improved portable leak detector technology to UE Systems, Inc.. This instrument was developed to detect leaks in fluid systems of critical launch and ground support equipment. This system incorporates innovative electronic circuitry, improved transducers, collecting horns, and contact sensors that provide a much higher degree of reliability, sensitivity and versatility over previously used systems. Potential commercial uses are pipelines, underground utilities, air-conditioning systems, petrochemical systems, aerospace, power transmission lines and medical devices.

  6. Research on automatic control system of greenhouse

    NASA Astrophysics Data System (ADS)

    Liu, Yi; Qi, Guoyang; Li, Zeyu; Wu, Qiannan; Meng, Yupeng

    2017-03-01

    This paper introduces a kind of automatic control system of single-chip microcomputer and a temperature and humidity sensor based on the greenhouse, describes the system's hardware structure, working principle and process, and a large number of experiments on the effect of the control system, the results show that the system can ideally control temperature and room temperature and humidity, can be used in indoor breeding and planting, and has the versatility and portability.

  7. Northeast Artificial Intelligence Consortium (NAIC) Review of Technical Tasks. Volume 2, Part 1.

    DTIC Science & Technology

    1987-07-01

    34- . 6.2 Transformation Invariant Attributes for S Digitized Object Outlines ................................. 469 6.3 Design of an Inference Engine for an...Attributes for Digital Object Outlines ...................................... 597 7 SPEECH UNDERSTANDING RESEARCH ( Rochester Institute of Technology...versatile maintenance expert system ES) for trouble-shooting--’ digital circuits. +" Some diagnosis systems, such as MYCLN [19] for medical diagnosis and CRIB

  8. Strength Is in Numbers: Can Concordant Artificial Listeners Improve Prediction of Emotion from Speech?

    PubMed

    Martinelli, Eugenio; Mencattini, Arianna; Daprati, Elena; Di Natale, Corrado

    2016-01-01

    Humans can communicate their emotions by modulating facial expressions or the tone of their voice. Albeit numerous applications exist that enable machines to read facial emotions and recognize the content of verbal messages, methods for speech emotion recognition are still in their infancy. Yet, fast and reliable applications for emotion recognition are the obvious advancement of present 'intelligent personal assistants', and may have countless applications in diagnostics, rehabilitation and research. Taking inspiration from the dynamics of human group decision-making, we devised a novel speech emotion recognition system that applies, for the first time, a semi-supervised prediction model based on consensus. Three tests were carried out to compare this algorithm with traditional approaches. Labeling performances relative to a public database of spontaneous speeches are reported. The novel system appears to be fast, robust and less computationally demanding than traditional methods, allowing for easier implementation in portable voice-analyzers (as used in rehabilitation, research, industry, etc.) and for applications in the research domain (such as real-time pairing of stimuli to participants' emotional state, selective/differential data collection based on emotional content, etc.).

  9. Speech chronemics--a hidden dimension of speech. Theoretical background, measurement and clinical validity.

    PubMed

    Krüger, H P

    1989-02-01

    The term "speech chronemics" is introduced to characterize a research strategy which extracts from the physical qualities of the speech signal only the pattern of ons ("speaking") and offs ("pausing"). The research in this field can be structured into the methodological dimension "unit of time", "number of speakers", and "quality of the prosodic measures". It is shown that a researcher's actual decision for one method largely determines the outcome of his study. Then, with the Logoport a new portable measurement device is presented. It enables the researcher to study speaking behavior over long periods of time (up to 24 hours) in the normal environment of his subjects. Two experiments are reported. The first shows the validity of articulation pauses for variations in the physiological state of the organism. The second study proves a new betablocking agent to have sociotropic effects: in a long-term trial socially high-strung subjects showed an improved interaction behavior (compared to placebo and socially easy-going persons) in their everyday life. Finally, the need for a comprehensive theoretical foundation and for standardization of measurement situations and methods is emphasized.

  10. A compact and portable optofluidic device for detection of liquid properties and label-free sensing

    NASA Astrophysics Data System (ADS)

    Lahoz, F.; Martín, I. R.; Walo, D.; Gil-Rostra, J.; Yubero, F.; Gonzalez-Elipe, A. R.

    2017-06-01

    Optofluidic lasers have been widely investigated over the last few years mainly because they can be easily integrated in sensor devices. However, high power pulse lasers are required as excitation sources, which, in practice, limit the portability of the system. Trying to overcome some of these limitations, in this paper we propose the combined use of a small CW laser with a Fabry-Perot optofluidic planar microcavity showing high sensitivity and versatility for detection of liquid properties and label-free sensing. Firstly, a fluorescein solution in ethanol is used to demonstrate the high performances of the FP microcavity as a temperature sensor both in the laser (high pump power above laser threshold) and in the fluorescence (low pump power) regimes. A shift in the wavelength of the resonant cavity modes is used to detect changes in the temperature and our results show that high sensitivities could be already obtained using cheap and portable CW diode lasers. In the second part of the paper, the demonstration of this portable device for label-free sensing is illustrated under low CW pumping. The wavelength positions of the optofluidic resonant modes are used to detect glucose concentrations in water solutions using a protein labelled with a fluorescent dye as the active medium.

  11. Application of EVA guidelines and design criteria. Volume 2: EVA workstation conceptual designs

    NASA Technical Reports Server (NTRS)

    Brown, N. E.

    1973-01-01

    Several EV workstation concepts were developed and are documented. The workstation concepts were developed following a comprehensive analysis of potential EV missions, functions, and tasks as interpreted from NASA and contractor space shuttle and space station studies, mission models, and related reports. The design of a versatile, portable EVA workstation is aimed at reducing the design and development costs for each mission and aiding in the development of on-orbit serviceable payloads.

  12. Portable mini-chamber for temperature dependent studies using small angle and wide angle x-ray scattering

    NASA Astrophysics Data System (ADS)

    Dev, Arun Singh; Kumar, Dileep; Potdar, Satish; Pandit, Pallavi; Roth, Stephan V.; Gupta, Ajay

    2018-04-01

    The present work describes the design and performance of a vacuum compatible portable mini chamber for temperature dependent GISAXS and GIWAXS studies of thin films and multilayer structures. The water cooled body of the chamber allows sample annealing up to 900 K using ultra high vacuum compatible (UHV) pyrolytic boron nitride heater, thus making it possible to study the temperature dependent evolution of structure and morphology of two-dimensional nanostructured materials. Due to its light weight and small size, the chamber is portable and can be accommodated at synchrotron facilities worldwide. A systematic illustration of the versatility of the chamber has been demonstrated at beamline P03, PETRA-III, DESY, Hamburg, Germany. Temperature dependent grazing incidence small angle x-ray scattering (GISAXS) and grazing incidence wide angle x-ray scattering (GIWAXS) measurements were performed on oblique angle deposited Co/Ag multilayer structure, which jointly revealed that the surface diffusion in Co columns in Co/Ag multilayer enhances by increasing temperature from RT to ˜573 K. This results in a morphology change from columnar tilted structure to densely packed morphological isotropic multilayer.

  13. A versatile calibration procedure for portable coded aperture gamma cameras and RGB-D sensors

    NASA Astrophysics Data System (ADS)

    Paradiso, V.; Crivellaro, A.; Amgarou, K.; de Lanaute, N. Blanc; Fua, P.; Liénard, E.

    2018-04-01

    The present paper proposes a versatile procedure for the geometrical calibration of coded aperture gamma cameras and RGB-D depth sensors, using only one radioactive point source and a simple experimental set-up. Calibration data is then used for accurately aligning radiation images retrieved by means of the γ-camera with the respective depth images computed with the RGB-D sensor. The system resulting from such a combination is thus able to retrieve, automatically, the distance of radioactive hotspots by means of pixel-wise mapping between gamma and depth images. This procedure is of great interest for a wide number of applications, ranging from precise automatic estimation of the shape and distance of radioactive objects to Augmented Reality systems. Incidentally, the corresponding results validated the choice of a perspective design model for a coded aperture γ-camera.

  14. Portable Language-Independent Adaptive Translation from OCR. Phase 1

    DTIC Science & Technology

    2009-04-01

    including brute-force k-Nearest Neighbors ( kNN ), fast approximate kNN using hashed k-d trees, classification and regression trees, and locality...achieved by refinements in ground-truthing protocols. Recent algorithmic improvements to our approximate kNN classifier using hashed k-D trees allows...recent years discriminative training has been shown to outperform phonetic HMMs estimated using ML for speech recognition. Standard ML estimation

  15. Changes in objective acoustic measurements and subjective voice complaints in call center customer-service advisors during one working day.

    PubMed

    Lehto, Laura; Laaksonen, Laura; Vilkman, Erkki; Alku, Paavo

    2008-03-01

    The aim of this study was to investigate how different acoustic parameters, extracted both from speech pressure waveforms and glottal flows, can be used in measuring vocal loading in modern working environments and how these parameters reflect the possible changes in the vocal function during a working day. In addition, correlations between objective acoustic parameters and subjective voice symptoms were addressed. The subjects were 24 female and 8 male customer-service advisors, who mainly use telephone during their working hours. Speech samples were recorded from continuous speech four times during a working day and voice symptom questionnaires were completed simultaneously. Among the various objective parameters, only F0 resulted in a statistically significant increase for both genders. No correlations between the changes in objective and subjective parameters appeared. However, the results encourage researchers within the field of occupational voice use to apply versatile measurement techniques in studying occupational voice loading.

  16. Electropalatography in home training of retracted articulation in a Swedish child with cleft palate: effect on articulation pattern and speech.

    PubMed

    Lohmander, Anette; Henriksson, Cecilia; Havstam, Christina

    2010-12-01

    The aim was to evaluate the effectiveness of electropalatography (EPG) in home training of persistent articulation errors in an 11-year-old Swedish girl born with isolated cleft palate. The /t/ and /s/ sounds were trained in a single subject design across behaviours during an eight month period using a portable training unit (PTU). Both EPG analysis and perceptual analysis showed an improvement in the production of /t/ and /s/ in words and sentences after therapy. Analysis of tongue-contact patterns showed that the participant had more normal articulatory patterns of /t/ and /s/ after just 2 months (after approximately 8 hours of training) respectively. No statistically significant transfer by means of intelligibility in connected speech was found. The present results show that EPG home training can be a sufficient method for treating persistent speech disorders associated with cleft palate. Methods for transfer from function (articulation) to activity (intelligibility) need to be explored.

  17. Collaborative Recurrent Neural Networks forDynamic Recommender Systems

    DTIC Science & Technology

    2016-11-22

    formulation leads to an efficient and practical method. Furthermore, we demonstrate the versatility of our model by applying it to two different tasks: music ...form (user id, location id, check-in time). The LastFM9 dataset consists of sequences of songs played by a user’s music player collected by using a...Jeffrey L Elman. Finding structure in time. Cognitive science, 14(2), 1990. Alex Graves, Abdel-rahman Mohamed, and Geoffrey Hinton. Speech recognition

  18. White-Light Optical Information Processing and Holography.

    DTIC Science & Technology

    1985-07-29

    this technique is the processing system does not require to carry its own light source. It is very suitable for spaceborne and satellite application. We...developed a technique of generating a spatialtrequency color coded speech spectrogram with a white-light optical system . This system not only offers a low...that the annoying moire fringes can be eliminated. In short, we have once again demonstrated the versatility of the white-light progress system ; a

  19. Strength Is in Numbers: Can Concordant Artificial Listeners Improve Prediction of Emotion from Speech?

    PubMed Central

    Martinelli, Eugenio; Mencattini, Arianna; Di Natale, Corrado

    2016-01-01

    Humans can communicate their emotions by modulating facial expressions or the tone of their voice. Albeit numerous applications exist that enable machines to read facial emotions and recognize the content of verbal messages, methods for speech emotion recognition are still in their infancy. Yet, fast and reliable applications for emotion recognition are the obvious advancement of present ‘intelligent personal assistants’, and may have countless applications in diagnostics, rehabilitation and research. Taking inspiration from the dynamics of human group decision-making, we devised a novel speech emotion recognition system that applies, for the first time, a semi-supervised prediction model based on consensus. Three tests were carried out to compare this algorithm with traditional approaches. Labeling performances relative to a public database of spontaneous speeches are reported. The novel system appears to be fast, robust and less computationally demanding than traditional methods, allowing for easier implementation in portable voice-analyzers (as used in rehabilitation, research, industry, etc.) and for applications in the research domain (such as real-time pairing of stimuli to participants’ emotional state, selective/differential data collection based on emotional content, etc.). PMID:27563724

  20. Identification of vibrational signatures from short chains of interlinked molecule-nanoparticle junctions obtained by inelastic electron tunnelling spectroscopy

    NASA Astrophysics Data System (ADS)

    Jafri, S. H. M.; Löfås, H.; Fransson, J.; Blom, T.; Grigoriev, A.; Wallner, A.; Ahuja, R.; Ottosson, H.; Leifer, K.

    2013-05-01

    Short chains containing a series of metal-molecule-nanoparticle nanojunctions are a nano-material system with the potential to give electrical signatures close to those from single molecule experiments while enabling us to build portable devices on a chip. Inelastic electron tunnelling spectroscopy (IETS) measurements provide one of the most characteristic electrical signals of single and few molecules. In interlinked molecule-nanoparticle (NP) chains containing typically 5-7 molecules in a chain, the spectrum is expected to be a superposition of the vibrational signatures of individual molecules. We have established a stable and reproducible molecule-AuNP multi-junction by placing a few 1,8-octanedithiol (ODT) molecules onto a versatile and portable nanoparticle-nanoelectrode platform and measured for the first time vibrational molecular signatures at complex and coupled few-molecule-NP junctions. From quantum transport calculations, we model the IETS spectra and identify vibrational modes as well as the number of molecules contributing to the electron transport in the measured spectra.Short chains containing a series of metal-molecule-nanoparticle nanojunctions are a nano-material system with the potential to give electrical signatures close to those from single molecule experiments while enabling us to build portable devices on a chip. Inelastic electron tunnelling spectroscopy (IETS) measurements provide one of the most characteristic electrical signals of single and few molecules. In interlinked molecule-nanoparticle (NP) chains containing typically 5-7 molecules in a chain, the spectrum is expected to be a superposition of the vibrational signatures of individual molecules. We have established a stable and reproducible molecule-AuNP multi-junction by placing a few 1,8-octanedithiol (ODT) molecules onto a versatile and portable nanoparticle-nanoelectrode platform and measured for the first time vibrational molecular signatures at complex and coupled few-molecule-NP junctions. From quantum transport calculations, we model the IETS spectra and identify vibrational modes as well as the number of molecules contributing to the electron transport in the measured spectra. Electronic supplementary information (ESI) available: Methods and materials. Details of the ab initio calculation of molecular vibrations and inelastic spectra of ODT between two Au electrodes. A model of carrier transport through the molecular junctions. See DOI: 10.1039/c3nr00505d

  1. A versatile pitch tracking algorithm: from human speech to killer whale vocalizations.

    PubMed

    Shapiro, Ari Daniel; Wang, Chao

    2009-07-01

    In this article, a pitch tracking algorithm [named discrete logarithmic Fourier transformation-pitch detection algorithm (DLFT-PDA)], originally designed for human telephone speech, was modified for killer whale vocalizations. The multiple frequency components of some of these vocalizations demand a spectral (rather than temporal) approach to pitch tracking. The DLFT-PDA algorithm derives reliable estimations of pitch and the temporal change of pitch from the harmonic structure of the vocal signal. Scores from both estimations are combined in a dynamic programming search to find a smooth pitch track. The algorithm is capable of tracking killer whale calls that contain simultaneous low and high frequency components and compares favorably across most signal to noise ratio ranges to the peak-picking and sidewinder algorithms that have been used for tracking killer whale vocalizations previously.

  2. Measurement of strains by means of electro-optics holography

    NASA Astrophysics Data System (ADS)

    Sciammarella, Cesar A.; Bhat, Gopalakrishna K.; Albertazzi, Armando, Jr.

    1991-03-01

    The use of a TV camera as a recording medium and the observation of whole field displacements in real time makes holographic TV a very interesting and powerful tool in a variety of areas from NDE to research and development. The paper presents new developments in the field that add to the versatility of the technique by introducing portability and methods to obtain accurate quantitative results. Examples of applications are given to the measurement of strains both at room and at high temperatures and strain measurements at the microscopic level. 1.

  3. USAF Bioenvironmental Noise Data Handbook. Volume 165: MC-1 heater, duct type, portable

    NASA Astrophysics Data System (ADS)

    Rau, T. H.

    1982-06-01

    The MC-1 heater is a gasoline-motor driven, portable ground heater used primarily for cockpit and cabin temperature control. This report provides measured and extrapolated data defining the bioacoustic environments produced by this unit operating outdoors on a concrete apron at normal rated conditions. Near-field data are reported for 37 locations in a wide variety of physical and psychoacoustic measures: overall and band sound pressure levels, C-weighted and A-weighted sound levels, preferred speech interference level, perceived noise levels, and limiting times for total daily exposure of personnel with and without standard Air Force ear protectors. Far-field data measured at 36 locations are normalized to standard meteorological conditions and extrapolated from 10 1600 meters to derive sets of equal-value contours for these same seven acoustic measures as functions of angle and distance from the source.

  4. Identification of vibrational signatures from short chains of interlinked molecule-nanoparticle junctions obtained by inelastic electron tunnelling spectroscopy.

    PubMed

    Jafri, S H M; Löfås, H; Fransson, J; Blom, T; Grigoriev, A; Wallner, A; Ahuja, R; Ottosson, H; Leifer, K

    2013-06-07

    Short chains containing a series of metal-molecule-nanoparticle nanojunctions are a nano-material system with the potential to give electrical signatures close to those from single molecule experiments while enabling us to build portable devices on a chip. Inelastic electron tunnelling spectroscopy (IETS) measurements provide one of the most characteristic electrical signals of single and few molecules. In interlinked molecule-nanoparticle (NP) chains containing typically 5-7 molecules in a chain, the spectrum is expected to be a superposition of the vibrational signatures of individual molecules. We have established a stable and reproducible molecule-AuNP multi-junction by placing a few 1,8-octanedithiol (ODT) molecules onto a versatile and portable nanoparticle-nanoelectrode platform and measured for the first time vibrational molecular signatures at complex and coupled few-molecule-NP junctions. From quantum transport calculations, we model the IETS spectra and identify vibrational modes as well as the number of molecules contributing to the electron transport in the measured spectra.

  5. Microfabrication and Applications of Opto-Microfluidic Sensors

    PubMed Central

    Zhang, Daiying; Men, Liqiu; Chen, Qiying

    2011-01-01

    A review of research activities on opto-microfluidic sensors carried out by the research groups in Canada is presented. After a brief introduction of this exciting research field, detailed discussion is focused on different techniques for the fabrication of opto-microfluidic sensors, and various applications of these devices for bioanalysis, chemical detection, and optical measurement. Our current research on femtosecond laser microfabrication of optofluidic devices is introduced and some experimental results are elaborated. The research on opto-microfluidics provides highly sensitive opto-microfluidic sensors for practical applications with significant advantages of portability, efficiency, sensitivity, versatility, and low cost. PMID:22163904

  6. New Ideas for Speech Recognition and Related Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holzrichter, J F

    The ideas relating to the use of organ motion sensors for the purposes of speech recognition were first described by.the author in spring 1994. During the past year, a series of productive collaborations between the author, Tom McEwan and Larry Ng ensued and have lead to demonstrations, new sensor ideas, and algorithmic descriptions of a large number of speech recognition concepts. This document summarizes the basic concepts of recognizing speech once organ motions have been obtained. Micro power radars and their uses for the measurement of body organ motions, such as those of the heart and lungs, have been demonstratedmore » by Tom McEwan over the past two years. McEwan and I conducted a series of experiments, using these instruments, on vocal organ motions beginning in late spring, during which we observed motions of vocal folds (i.e., cords), tongue, jaw, and related organs that are very useful for speech recognition and other purposes. These will be reviewed in a separate paper. Since late summer 1994, Lawrence Ng and I have worked to make many of the initial recognition ideas more rigorous and to investigate the applications of these new ideas to new speech recognition algorithms, to speech coding, and to speech synthesis. I introduce some of those ideas in section IV of this document, and we describe them more completely in the document following this one, UCRL-UR-120311. For the design and operation of micro-power radars and their application to body organ motions, the reader may contact Tom McEwan directly. The capability for using EM sensors (i.e., radar units) to measure body organ motions and positions has been available for decades. Impediments to their use appear to have been size, excessive power, lack of resolution, and lack of understanding of the value of organ motion measurements, especially as applied to speech related technologies. However, with the invention of very low power, portable systems as demonstrated by McEwan at LLNL researchers have begun to think differently about practical applications of such radars. In particular, his demonstrations of heart and lung motions have opened up many new areas of application for human and animal measurements.« less

  7. Immediate effects of AAF devices on the characteristics of stuttering: a clinical analysis.

    PubMed

    Unger, Julia P; Glück, Christian W; Cholewa, Jürgen

    2012-06-01

    The present study investigated the immediate effects of altered auditory feedback (AAF) and one Inactive Condition (AAF parameters set to 0) on clinical attributes of stuttering during scripted and spontaneous speech. Two commercially available, portable AAF devices were used to create the combined delayed auditory feedback (DAF) and frequency altered feedback (FAF) effects. Thirty adults, who stutter, aged 18-68 years (M=36.5; SD=15.2), participated in this investigation. Each subject produced four sets of 5-min of oral reading, three sets of 5-min monologs as well as 10-min dialogs. These speech samples were analyzed to detect changes in descriptive features of stuttering (frequency, duration, speech/articulatory rate, core behaviors) across the various speech samples and within two SSI-4 (Riley, 2009) based severity ratings. A statistically significant difference was found in the frequency of stuttered syllables (%SS) during both Active Device conditions (p=.000) for all speech samples. The most sizable reductions in %SS occurred within scripted speech. In the analysis of stuttering type, it was found that blocks were reduced significantly (Device A: p=.017; Device B: p=.049). To evaluate the impact on severe and mild stuttering, participants were grouped into two SSI-4 based categories; mild and moderate-severe. During the Inactive Condition those participants within the moderate-severe group (p=.024) showed a statistically significant reduction in overall disfluencies. This result indicates, that active AAF parameters alone may not be the sole cause of a fluency-enhancement when using a technical speech aid. The reader will learn and be able to describe: (1) currently available scientific evidence on the use of altered auditory feedback (AAF) during scripted and spontaneous speech, (2) which characteristics of stuttering are impacted by an AAF device (frequency, duration, core behaviors, speech & articulatory rate, stuttering severity), (3) the effects of an Inactive Condition on people who stutter (PWS) falling into two severity groups, and (4) how the examined participants perceived the use of AAF devices. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. NWR (National Weather Service) voice synthesis project, phase 1

    NASA Astrophysics Data System (ADS)

    Sampson, G. W.

    1986-01-01

    The purpose of the NOAA Weather Radio (NWR) Voice Synthesis Project is to provide a demonstration of the current voice synthesis technology. Phase 1 of this project is presented, providing a complete automation of an hourly surface aviation observation for broadcast over NWR. In examining the products currently available on the market, the decision was made that synthetic voice technology does not have the high quality speech required for broadcast over the NWR. Therefore the system presented uses the phrase concatenation type of technology for a very high quality, versatile, voice synthesis system.

  9. The Portable Chemical Sterilizer (PCS), D-FENS, and D-FEND ALL: novel chlorine dioxide decontamination technologies for the military.

    PubMed

    Doona, Christopher J; Feeherry, Florence E; Setlow, Peter; Malkin, Alexander J; Leighton, Terrence J

    2014-06-29

    There is a stated Army need for a field-portable, non-steam sterilizer technology that can be used by Forward Surgical Teams, Dental Companies, Veterinary Service Support Detachments, Combat Support Hospitals, and Area Medical Laboratories to sterilize surgical instruments and to sterilize pathological specimens prior to disposal in operating rooms, emergency treatment areas, and intensive care units. The following ensemble of novel, 'clean and green' chlorine dioxide technologies are versatile and flexible to adapt to meet a number of critical military needs for decontamination(6,15). Specifically, the Portable Chemical Sterilizer (PCS) was invented to meet urgent battlefield needs and close critical capability gaps for energy-independence, lightweight portability, rapid mobility, and rugged durability in high intensity forward deployments(3). As a revolutionary technological breakthrough in surgical sterilization technology, the PCS is a Modern Field Autoclave that relies on on-site, point-of-use, at-will generation of chlorine dioxide instead of steam. Two (2) PCS units sterilize 4 surgical trays in 1 hr, which is the equivalent throughput of one large steam autoclave (nicknamed "Bertha" in deployments because of its cumbersome size, bulky dimensions, and weight). However, the PCS operates using 100% less electricity (0 vs. 9 kW) and 98% less water (10 vs. 640 oz.), significantly reduces weight by 95% (20 vs. 450 lbs, a 4-man lift) and cube by 96% (2.1 vs. 60.2 ft(3)), and virtually eliminates the difficult challenges in forward deployments of repairs and maintaining reliable operation, lifting and transporting, and electrical power required for steam autoclaves.

  10. A portable near-infrared fluorescence image overlay device for surgical navigation (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    McWade, Melanie A.

    2016-03-01

    A rise in the use of near-infrared (NIR) fluorescent dyes or intrinsic fluorescent markers for surgical guidance and tissue diagnosis has triggered the development of NIR fluorescence imaging systems. Because NIR wavelengths are invisible to the naked eye, instrumentation must allow surgeons to visualize areas of high fluorescence. Current NIR fluorescence imaging systems have limited ease-of-use because they display fluorescent information on remote display monitors that require surgeons to divert attention away from the patient to identify the location of tissue fluorescence. Furthermore, some systems lack simultaneous visible light imaging which provides valuable spatial context to fluorescence images. We have developed a novel, portable NIR fluorescence imaging approach for intraoperative surgical guidance that provides information for surgical navigation within the clinician's line of sight. The system utilizes a NIR CMOS detector to collect excited NIR fluorescence from the surgical field. Tissues with NIR fluorescence are overlaid with visible light to provide information on tissue margins directly on the surgical field. In vitro studies have shown this versatile imaging system can be applied to applications with both extrinsic NIR contrast agents such as indocyanine green and weaker sources of biological fluorescence such as parathyroid gland tissue. This non-invasive, portable NIR fluorescence imaging system overlays an image directly on tissue, potentially allowing surgical decisions to be made quicker and with greater ease-of-use than current NIR fluorescence imaging systems.

  11. Portable device for the detection of colorimetric assays

    PubMed Central

    Nowak, E.; Kawchuk, J.; Hoorfar, M.; Najjaran, H.

    2017-01-01

    In this work, a low-cost, portable device is developed to detect colorimetric assays for in-field and point-of-care (POC) analysis. The device can rapidly detect both pH values and nitrite concentrations of five different samples, simultaneously. After mixing samples with specific reagents, a high-resolution digital camera collects a picture of the sample, and a single-board computer processes the image in real time to identify the hue–saturation–value coordinates of the image. An internal light source reduces the effect of any ambient light so the device can accurately determine the corresponding pH values or nitrite concentrations. The device was purposefully designed to be low-cost, yet versatile, and the accuracy of the results have been compared to those from a conventional method. The results obtained for pH values have a mean standard deviation of 0.03 and a correlation coefficient R2 of 0.998. The detection of nitrites is between concentrations of 0.4–1.6 mg l−1, with a low detection limit of 0.2 mg l−1, and has a mean standard deviation of 0.073 and an R2 value of 0.999. The results represent great potential of the proposed portable device as an excellent analytical tool for POC colorimetric analysis and offer broad accessibility in resource-limited settings. PMID:29291093

  12. Bioinspired M-13 bacteriophage-based photonic nose for differential cell recognition† †Electronic supplementary information (ESI) available: Instrumentation, diagrams, protein sequences and additional results. See DOI: 10.1039/c6sc02021f Click here for additional data file.

    PubMed Central

    Moon, Jong-Sik; Kim, Won-Geun; Shin, Dong-Myeong; Lee, So-Young; Kim, Chuntae; Lee, Yujin; Han, Jiye; Kim, Kyujung

    2017-01-01

    A bioinspired M-13 bacteriophage-based photonic nose was developed for differential cell recognition. The M-13 bacteriophage-based photonic nose exhibits characteristic color patterns when phage bundle nanostructures, which were genetically modified to selectively capture vapor phase molecules, are structurally deformed. We characterized the color patterns of the phage bundle nanostructure in response to cell proliferation via several biomarkers differentially produced by cells, including hydrazine, o-xylene, ethylbenzene, ethanol and toluene. A specific color enables the successful identification of different types of molecular and cellular species. Our sensing technique utilized the versatile M-13 bacteriophage as a building block for fabricating bioinspired photonic crystals, which enables ease of fabrication and tunable selectivity through genetic engineering. Our simple and versatile bioinspired photonic nose could have possible applications in sensors for human health and national security, food discrimination, environmental monitoring, and portable and wearable sensors. PMID:28572902

  13. Hear today, gone tomorrow: an assessment of portable entertainment player use and hearing acuity in a community sample.

    PubMed

    Shah, Samit; Gopal, Bharat; Reis, Janet; Novak, Michael

    2009-01-01

    Noise-induced hearing loss (NIHL) is a common but preventable disability. The purpose of this study was to assess the understanding of NIHL in a community sample in the context of exposure to portable music players, including MP3 players, and personal hearing acuity as tested with the Welch Allyn Audioscope 3. A cross-sectional convenience sample of 94 adults (18 to 65 years old) at a university recreation center completed an analysis of personal use of portable digital music players (MP3 players), concerns about hearing loss, and a 3-dB-level hearing test at 4 levels of speech frequency in a low ambient noise setting. The majority of participants (85%) were concerned about hearing loss, willing to protect their hearing with lower volume (77%), had little measurable hearing loss but were exposed to longer and louder periods of noise than other national samples, and mistakenly felt that NIHL is a medically reversible condition. Many (40%) also wanted their family medicine physician to be more concerned about their hearing. Family medicine physicians are in a key position to provide basic information on the preventability and negative consequences of NIHL, as well as to identify and refer patients with identified hearing loss.

  14. Array Biosensor for Toxin Detection: Continued Advances

    PubMed Central

    Taitt, Chris Rowe; Shriver-Lake, Lisa C.; Ngundi, Miriam M.; Ligler, Frances S.

    2008-01-01

    The following review focuses on progress made in the last five years with the NRL Array Biosensor, a portable instrument for rapid and simultaneous detection of multiple targets. Since 2003, the Array Biosensor has been automated and miniaturized for operation at the point-of-use. The Array Biosensor has also been used to demonstrate (1) quantitative immunoassays against an expanded number of toxins and toxin indicators in food and clinical fluids, and (2) the efficacy of semi-selective molecules as alternative recognition moieties. Blind trials, with unknown samples in a variety of matrices, have demonstrated the versatility, sensitivity, and reliability of the automated system. PMID:27873991

  15. The Portable Chemical Sterilizer (PCS), D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military

    PubMed Central

    Doona, Christopher J.; Feeherry, Florence E.; Setlow, Peter; Malkin, Alexander J.; Leighton, Terrence J.

    2014-01-01

    There is a stated Army need for a field-portable, non-steam sterilizer technology that can be used by Forward Surgical Teams, Dental Companies, Veterinary Service Support Detachments, Combat Support Hospitals, and Area Medical Laboratories to sterilize surgical instruments and to sterilize pathological specimens prior to disposal in operating rooms, emergency treatment areas, and intensive care units. The following ensemble of novel, ‘clean and green’ chlorine dioxide technologies are versatile and flexible to adapt to meet a number of critical military needs for decontamination6,15. Specifically, the Portable Chemical Sterilizer (PCS) was invented to meet urgent battlefield needs and close critical capability gaps for energy-independence, lightweight portability, rapid mobility, and rugged durability in high intensity forward deployments3. As a revolutionary technological breakthrough in surgical sterilization technology, the PCS is a Modern Field Autoclave that relies on on-site, point-of-use, at-will generation of chlorine dioxide instead of steam. Two (2) PCS units sterilize 4 surgical trays in 1 hr, which is the equivalent throughput of one large steam autoclave (nicknamed “Bertha” in deployments because of its cumbersome size, bulky dimensions, and weight). However, the PCS operates using 100% less electricity (0 vs. 9 kW) and 98% less water (10 vs. 640 oz.), significantly reduces weight by 95% (20 vs. 450 lbs, a 4-man lift) and cube by 96% (2.1 vs. 60.2 ft3), and virtually eliminates the difficult challenges in forward deployments of repairs and maintaining reliable operation, lifting and transporting, and electrical power required for steam autoclaves. PMID:24998679

  16. Structuring Broadcast Audio for Information Access

    NASA Astrophysics Data System (ADS)

    Gauvain, Jean-Luc; Lamel, Lori

    2003-12-01

    One rapidly expanding application area for state-of-the-art speech recognition technology is the automatic processing of broadcast audiovisual data for information access. Since much of the linguistic information is found in the audio channel, speech recognition is a key enabling technology which, when combined with information retrieval techniques, can be used for searching large audiovisual document collections. Audio indexing must take into account the specificities of audio data such as needing to deal with the continuous data stream and an imperfect word transcription. Other important considerations are dealing with language specificities and facilitating language portability. At Laboratoire d'Informatique pour la Mécanique et les Sciences de l'Ingénieur (LIMSI), broadcast news transcription systems have been developed for seven languages: English, French, German, Mandarin, Portuguese, Spanish, and Arabic. The transcription systems have been integrated into prototype demonstrators for several application areas such as audio data mining, structuring audiovisual archives, selective dissemination of information, and topic tracking for media monitoring. As examples, this paper addresses the spoken document retrieval and topic tracking tasks.

  17. Textual standardization and the DSM-5 "common language".

    PubMed

    Kelly, Patty A

    2014-06-01

    In February 2010, the American Psychiatric Association (APA) launched their DSM-5 website with details about the development of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). The APA invited "the general public" to review the draft diagnostic criteria and provide written comments and suggestions. This revision marks the first time the APA has solicited public review of their diagnostic manual. This article analyzes reported speech on the DSM-5 draft diagnostic criteria for the classification Posttraumatic Stress Disorder. It demonstrates how textual standardization facilitates the cultural portability of the DSM-5 diagnostic criteria such that a community of speakers beyond the borders of the APA come to be seen as exemplary speakers, writers, and revisers of the professional style. Furthermore, analysis shows how co-authoring practices recontextualize the "voice" and persona of putative patient reported speech on Criterion D2. As a consequence of textual standardization, spoken discourse becomes recontextualized as the product of scientific inquiry and the organization of psychiatric knowledge.

  18. Video self-modeling as a post-treatment fluency recovery strategy for adults.

    PubMed

    Harasym, Jessica; Langevin, Marilyn; Kully, Deborah

    2015-06-01

    This multiple-baseline across subjects study investigated the effectiveness of video self-modeling (VSM) in reducing stuttering and bringing about improvements in associated self-report measures. Participants' viewing practices and perceptions of the utility of VSM also were explored. Three adult males who had previously completed speech restructuring treatment viewed VSM recordings twice per week for 6 weeks. Weekly speech data, treatment viewing logs, and pre- and post-treatment self-report measures were obtained. An exit interview also was conducted. Two participants showed a decreasing trend in stuttering frequency. All participants appeared to engage in fewer avoidance behaviors and had less expectations to stutter. All participants perceived that, in different ways, the VSM treatment had benefited them and all participants had unique viewing practices. Given the increasing availability and ease in using portable audio-visual technology, VSM appears to offer an economical and clinically useful tool for clients who are motivated to use the technology to recover fluency. Readers will be able to describe: (a) the tenets of video-self modeling; (b) the main components of video-self modeling as a fluency recovery treatment as used in this study; and (c) speech and self-report outcomes. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. BioLayout(Java): versatile network visualisation of structural and functional relationships.

    PubMed

    Goldovsky, Leon; Cases, Ildefonso; Enright, Anton J; Ouzounis, Christos A

    2005-01-01

    Visualisation of biological networks is becoming a common task for the analysis of high-throughput data. These networks correspond to a wide variety of biological relationships, such as sequence similarity, metabolic pathways, gene regulatory cascades and protein interactions. We present a general approach for the representation and analysis of networks of variable type, size and complexity. The application is based on the original BioLayout program (C-language implementation of the Fruchterman-Rheingold layout algorithm), entirely re-written in Java to guarantee portability across platforms. BioLayout(Java) provides broader functionality, various analysis techniques, extensions for better visualisation and a new user interface. Examples of analysis of biological networks using BioLayout(Java) are presented.

  20. The Measurement of Airflow Using Singing Helmet That Allows Free Movement of the Jaw.

    PubMed

    Jiang, Jack J; Hanna, Rewais B; Willey, Malachi V; Rieves, Adam

    2016-11-01

    Airflow measurement is a useful method of evaluating laryngeal physiology. We introduce a noninvasive device that measures airflow without restricting jaw movement or requiring phonation into a mouthpiece, thus facilitating measurement during singing and connected speech. Validation and human subject trials were conducted. Airflow measurements were obtained from 16 male and 16 female subjects during singing, speech, and constant vowel production tasks. A similar helmet was designed by Stevens and Mead in 1968. The new device validity was evaluated by comparing the measured volume of air to a known volume of administered air using a calibration syringe. Subjects were asked to voice sustained vowels at low, medium, and high vocal intensity, read two sentences at a conversational volume, and perform different singing exercises while airflow was recorded. The device accurately and reliably measured airflow with mean airflow values falling within previously published ranges. There was an experimentally determined response time of 0.173 ± 0.014 seconds. Subjects were able to comfortably perform speech and singing exercises. Male subjects had higher airflow for all sustained vowels (P < 0.05). Airflow was higher for abduction rather than adduction sentences (P < 0.05). No other portable device has been shown to measure airflow during singing and speech while allowing for free movement of the jaw. This device provides a more natural environment to measure airflow that could be used to help evaluate laryngeal function and aid in singing training. Copyright © 2016 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  1. A Field-Portable Cell Analyzer without a Microscope and Reagents.

    PubMed

    Seo, Dongmin; Oh, Sangwoo; Lee, Moonjin; Hwang, Yongha; Seo, Sungkyu

    2017-12-29

    This paper demonstrates a commercial-level field-portable lens-free cell analyzer called the NaviCell (No-stain and Automated Versatile Innovative cell analyzer) capable of automatically analyzing cell count and viability without employing an optical microscope and reagents. Based on the lens-free shadow imaging technique, the NaviCell (162 × 135 × 138 mm³ and 1.02 kg) has the advantage of providing analysis results with improved standard deviation between measurement results, owing to its large field of view. Importantly, the cell counting and viability testing can be analyzed without the use of any reagent, thereby simplifying the measurement procedure and reducing potential errors during sample preparation. In this study, the performance of the NaviCell for cell counting and viability testing was demonstrated using 13 and six cell lines, respectively. Based on the results of the hemocytometer ( de facto standard), the error rate (ER) and coefficient of variation (CV) of the NaviCell are approximately 3.27 and 2.16 times better than the commercial cell counter, respectively. The cell viability testing of the NaviCell also showed an ER and CV performance improvement of 5.09 and 1.8 times, respectively, demonstrating sufficient potential in the field of cell analysis.

  2. Gait-force model and inertial measurement unit-based measurements: A new approach for gait analysis and balance monitoring.

    PubMed

    Li, Xinan; Xu, Hongyuan; Cheung, Jeffrey T

    2016-12-01

    This work describes a new approach for gait analysis and balance measurement. It uses an inertial measurement unit (IMU) that can either be embedded inside a dynamically unstable platform for balance measurement or mounted on the lower back of a human participant for gait analysis. The acceleration data along three Cartesian coordinates is analyzed by the gait-force model to extract bio-mechanics information in both the dynamic state as in the gait analyzer and the steady state as in the balance scale. For the gait analyzer, the simple, noninvasive and versatile approach makes it appealing to a broad range of applications in clinical diagnosis, rehabilitation monitoring, athletic training, sport-apparel design, and many other areas. For the balance scale, it provides a portable platform to measure the postural deviation and the balance index under visual or vestibular sensory input conditions. Despite its simple construction and operation, excellent agreement has been demonstrated between its performance and the high-cost commercial balance unit over a wide dynamic range. The portable balance scale is an ideal tool for routine monitoring of balance index, fall-risk assessment, and other balance-related health issues for both clinical and household use.

  3. Compact ultrafast semiconductor disk laser: targeting GFP based nonlinear applications in living organisms

    PubMed Central

    Aviles-Espinosa, Rodrigo; Filippidis, George; Hamilton, Craig; Malcolm, Graeme; Weingarten, Kurt J.; Südmeyer, Thomas; Barbarin, Yohan; Keller, Ursula; Santos, Susana I.C.O; Artigas, David; Loza-Alvarez, Pablo

    2011-01-01

    We present a portable ultrafast Semiconductor Disk Laser (SDL) (or vertical extended cavity surface emitting laser—VECSELs), to be used for nonlinear microscopy. The SDL is modelocked using a quantum-dot semiconductor saturable absorber mirror (SESAM), delivering an average output power of 287 mW, with 1.5 ps pulses at 500 MHz and a central wavelength of 965 nm. Specifically, despite the fact of having long pulses and high repetition rates, we demonstrate the potential of this laser for Two-Photon Excited Fluorescence (TPEF) imaging of in vivo Caenorhabditis elegans (C. elegans) expressing Green Fluorescent Protein (GFP) in a set of neuronal processes and cell bodies. Efficient TPEF imaging is achieved due to the fact that this wavelength matches the peak of the two-photon action cross section of this widely used fluorescent marker. The SDL extended versatility is shown by presenting Second Harmonic Generation images of pharynx, uterus, body wall muscles and its potential to be used to excite other different commercial dyes. Importantly this non-expensive, turn-key, compact laser system could be used as a platform to develop portable nonlinear bio-imaging devices. PMID:21483599

  4. Reflex-free digital fundus photography using a simple and portable camera adaptor system. A viable alternative.

    PubMed

    Pirie, Chris G; Pizzirani, Stefano

    2011-12-01

    To describe a digital single lens reflex (dSLR) camera adaptor for posterior segment photography. A total of 30 normal canine and feline animals were imaged using a dSLR adaptor which mounts between a dSLR camera body and lens. Posterior segment viewing and imaging was performed with the aid of an indirect lens ranging from 28-90D. Coaxial illumination for viewing was provided by a single white light emitting diode (LED) within the adaptor, while illumination during exposure was provided by the pop-up flash or an accessory flash. Corneal and/or lens reflections were reduced using a pair of linear polarizers, having their azimuths perpendicular to one another. Quality high-resolution, reflection-free, digital images of the retina were obtained. Subjective image evaluation demonstrated the same amount of detail, as compared to a conventional fundus camera. A wide range of magnification(s) [1.2-4X] and/or field(s) of view [31-95 degrees, horizontal] were obtained by altering the indirect lens utilized. The described adaptor may provide an alternative to existing fundus camera systems. Quality images were obtained and the adapter proved to be versatile, portable and of low cost.

  5. Multi-wavelength Spatial LED illumination based detector for in vitro detection of Botulinum Neurotoxin A Activity

    PubMed Central

    Sun, Steven; Francis, Jesse; Sapsford, Kim E.; Kostov, Yordan; Rasooly, Avraham

    2010-01-01

    A portable and rapid detection system for the activity analysis of Botulinum Neurotoxins (BoNT) is needed for food safety and bio-security applications. To improve BoNT activity detection, a previously designed portable charge-coupled device (CCD) based detector was modified and equipped with a higher intensity more versatile multi-wavelength spatial light-emitting diode (LED) illumination, a faster CCD detector and the capability to simultaneously detect 30 samples. A FITC/DABCYL Förster Resonance Energy Transfer (FRET)-labeled peptide substrate (SNAP-25), with BoNT-A target cleavage site sequence was used to measure BoNT-A light chain (LcA) activity through the FITC fluorescence increase that occurs upon peptide substrate cleavage. For fluorescence excitation, a multi-wavelength spatial LED illuminator was used and compared to our previous electroluminescent (EL) strips. The LED illuminator was equipped with blue, green, red and white LEDs, covering a spectrum of 450-680 nm (red 610-650 nm, green 492-550 nm, blue 450-495 nm, and white LED 440-680 nm). In terms of light intensity, the blue LED was found to be ~80 fold higher than the previously used blue EL strips. When measuring the activity of LcA the CCD detector limit of detection (LOD) was found to be 0.08 nM LcA for both the blue LED (2 s exposure) and the blue EL (which require ≥60 s exposure) while the limits of quantitation (LOQ) is about 1 nM. The LOD for white LED was higher at 1.4 nM while the white EL was not used for the assay due to a high variable background. Unlike the weaker intensity EL illumination the high intensity LED illumination enabled shorter exposure times and allowed multi-wavelength illumination without the need to physically change the excitation strip, thus making spectrum excitation of multiple fluorophores possible increasing the versatility of the detector platform for a variety of optical detection assays. PMID:20498728

  6. Lab-On-a-Chip for carbon nanotubes based immunoassay detection of Staphylococcal Enterotoxin B (SEB).

    PubMed

    Yang, Minghui; Sun, Steven; Kostov, Yordan; Rasooly, Avraham

    2010-04-21

    We describe a new eight channel Lab-On-a-Chip (LOC) for a Carbon Nanotube (CNT) based immunoassay with optical detection of Staphylococcal Enterotoxin B (SEB) for food safety applications. In this work, we combined four biosensing elements: (1) CNT technology for primary antibody immobilization, (2) Enhanced Chemiluminescence (ECL) for light signal generation, (3) a cooled charge-coupled device (CCD) for detection and (4) polymer lamination technology for developing a point of care immunological assay for SEB detection. Our concept for developing versatile LOCs, which can be used for many different applications, is to use a modular design with interchangeable recognition elements (e.g. various antibodies) to determine the specificity. Polymer lamination technology was used for the fabrication of a six layer, syringe operated LOC capable of analyzing eight samples simultaneously. An anti-SEB antibody-nanotube mixture was immobilized onto a polycarbonate strip, to serve as an interchangeable ligand surface that was then bonded onto the LOC. SEB samples are loaded into the device and detected by an ELISA assay using Horse Radish Peroxidase (HRP) conjugated anti-SEB IgG as a secondary antibody and ECL, with detection by a previously described portable cooled CCD detector. Eight samples of SEB in buffer or soy milk were assayed simultaneously with a limit of detection of 0.1 ng mL(-1). CNT immobilization of the antibody increased the sensitivity of detection six fold. Use of a simple interchangeable immunological surface allows this LOC to be adapted to any immunoassay by simply replacing the ligand surface. A syringe was used to move fluids for this assay so no power is needed to operate the device. Our versatile portable point-of-care CCD detector combined with the LOC immunoassay method described here can be used to reduce the exposure of users to toxins and other biohazards when working outside the lab, as well as to simplify and increase sensitivity for many other types of immunological diagnostics and detection assays.

  7. A versatile approach to vacuum injection casting for materials research and development.

    PubMed

    Xu, Donghua; Xu, Yifan

    2017-03-01

    Vacuum injection casting (VIC) is important for research and development (R&D) of materials that are prone to oxidation at high temperatures, particularly metals and metallic alloys (e.g., metallic glasses and high entropy alloys). VIC in R&D laboratories often involves initial melting/alloying in a prior step, transporting the sample to a dedicated vacuum chamber, re-melting the sample in a quartz tube, and finally injecting the melt with an inert gas to a dedicated mold. Here we present a new approach to laboratory VIC that requires no sample transfer (for a variety of materials), no dedicated vacuum chamber/space nor dedicated mold, and hence provides more versatility and higher efficiency and yet lowers the capital equipment cost. Our approach takes advantage of the exceptional portability, thermal and chemical stability, and thermoplastic processability of quartz glass and uses quartz tubes for all the melting, re-melting, injection casting, and molding. In addition, our approach includes oxygen gettering to remove residual oxygen for all the steps and allows for slow or fast cooling (e.g., water quenching) upon injection. This paper focuses on the design, the procedures, and the versatile features of this new approach while also demonstrating the practical implementation of this approach and computational modeling of the heat transfer and the cooling rates for two exemplary cases. The new approach is expected to bring notable expedition to sample fabrication and materials discovery, as well as wider adoption of vacuum injection casting in materials science and condensed matter physics research laboratories.

  8. A versatile approach to vacuum injection casting for materials research and development

    NASA Astrophysics Data System (ADS)

    Xu, Donghua; Xu, Yifan

    2017-03-01

    Vacuum injection casting (VIC) is important for research and development (R&D) of materials that are prone to oxidation at high temperatures, particularly metals and metallic alloys (e.g., metallic glasses and high entropy alloys). VIC in R&D laboratories often involves initial melting/alloying in a prior step, transporting the sample to a dedicated vacuum chamber, re-melting the sample in a quartz tube, and finally injecting the melt with an inert gas to a dedicated mold. Here we present a new approach to laboratory VIC that requires no sample transfer (for a variety of materials), no dedicated vacuum chamber/space nor dedicated mold, and hence provides more versatility and higher efficiency and yet lowers the capital equipment cost. Our approach takes advantage of the exceptional portability, thermal and chemical stability, and thermoplastic processability of quartz glass and uses quartz tubes for all the melting, re-melting, injection casting, and molding. In addition, our approach includes oxygen gettering to remove residual oxygen for all the steps and allows for slow or fast cooling (e.g., water quenching) upon injection. This paper focuses on the design, the procedures, and the versatile features of this new approach while also demonstrating the practical implementation of this approach and computational modeling of the heat transfer and the cooling rates for two exemplary cases. The new approach is expected to bring notable expedition to sample fabrication and materials discovery, as well as wider adoption of vacuum injection casting in materials science and condensed matter physics research laboratories.

  9. Multi-microphone adaptive array augmented with visual cueing.

    PubMed

    Gibson, Paul L; Hedin, Dan S; Davies-Venn, Evelyn E; Nelson, Peggy; Kramer, Kevin

    2012-01-01

    We present the development of an audiovisual array that enables hearing aid users to converse with multiple speakers in reverberant environments with significant speech babble noise where their hearing aids do not function well. The system concept consists of a smartphone, a smartphone accessory, and a smartphone software application. The smartphone accessory concept is a multi-microphone audiovisual array in a form factor that allows attachment to the back of the smartphone. The accessory will also contain a lower power radio by which it can transmit audio signals to compatible hearing aids. The smartphone software application concept will use the smartphone's built in camera to acquire images and perform real-time face detection using the built-in face detection support of the smartphone. The audiovisual beamforming algorithm uses the location of talking targets to improve the signal to noise ratio and consequently improve the user's speech intelligibility. Since the proposed array system leverages a handheld consumer electronic device, it will be portable and low cost. A PC based experimental system was developed to demonstrate the feasibility of an audiovisual multi-microphone array and these results are presented.

  10. Changes in teachers' voice quality during a working day with and without electric sound amplification.

    PubMed

    Jónsdottir, Valdis; Laukkanen, Anne-Maria; Siikki, Ilona

    2003-01-01

    The present study investigated changes in the voice quality of teachers during a working day (a). in ordinary conditions and (b). when using electrical sound amplification while teaching. Classroom speech of 5 teachers was recorded with a portable DAT recorder and a head-mounted microphone during the first and the last lesson of a hard working day first in ordinary conditions and the following week using amplification. Long-term average spectrum and sound pressure level (SPL) analyses were made. The subjects' comments were gathered by questionnaire. Voice quality was evaluated by 2 speech trainers. With amplification, SPL was lower and the spectrum more tilted. Voice quality was evaluated to be better. The subjects reported less fatigue in the vocal mechanism. Spectral tilt decreased and SPL increased during the day. There was a tendency for perceived asthenia to decrease. No significant changes were observed in ordinary conditions. The acoustic changes seem to reflect a positive adaptation to vocal loading. Their absence may be a sign of vocal fatigue. Copyright 2003 S. Karger AG, Basel

  11. Cas9-mediated targeting of viral RNA in eukaryotic cells.

    PubMed

    Price, Aryn A; Sampson, Timothy R; Ratner, Hannah K; Grakoui, Arash; Weiss, David S

    2015-05-12

    Clustered, regularly interspaced, short palindromic repeats-CRISPR associated (CRISPR-Cas) systems are prokaryotic RNA-directed endonuclease machineries that act as an adaptive immune system against foreign genetic elements. Using small CRISPR RNAs that provide specificity, Cas proteins recognize and degrade nucleic acids. Our previous work demonstrated that the Cas9 endonuclease from Francisella novicida (FnCas9) is capable of targeting endogenous bacterial RNA. Here, we show that FnCas9 can be directed by an engineered RNA-targeting guide RNA to target and inhibit a human +ssRNA virus, hepatitis C virus, within eukaryotic cells. This work reveals a versatile and portable RNA-targeting system that can effectively function in eukaryotic cells and be programmed as an antiviral defense.

  12. 3D light scanning macrography.

    PubMed

    Huber, D; Keller, M; Robert, D

    2001-08-01

    The technique of 3D light scanning macrography permits the non-invasive surface scanning of small specimens at magnifications up to 200x. Obviating both the problem of limited depth of field inherent to conventional close-up macrophotography and the metallic coating required by scanning electron microscopy, 3D light scanning macrography provides three-dimensional digital images of intact specimens without the loss of colour, texture and transparency information. This newly developed technique offers a versatile, portable and cost-efficient method for the non-invasive digital and photographic documentation of small objects. Computer controlled device operation and digital image acquisition facilitate fast and accurate quantitative morphometric investigations, and the technique offers a broad field of research and educational applications in biological, medical and materials sciences.

  13. Cas9-mediated targeting of viral RNA in eukaryotic cells

    PubMed Central

    Price, Aryn A.; Sampson, Timothy R.; Ratner, Hannah K.; Grakoui, Arash; Weiss, David S.

    2015-01-01

    Clustered, regularly interspaced, short palindromic repeats–CRISPR associated (CRISPR-Cas) systems are prokaryotic RNA-directed endonuclease machineries that act as an adaptive immune system against foreign genetic elements. Using small CRISPR RNAs that provide specificity, Cas proteins recognize and degrade nucleic acids. Our previous work demonstrated that the Cas9 endonuclease from Francisella novicida (FnCas9) is capable of targeting endogenous bacterial RNA. Here, we show that FnCas9 can be directed by an engineered RNA-targeting guide RNA to target and inhibit a human +ssRNA virus, hepatitis C virus, within eukaryotic cells. This work reveals a versatile and portable RNA-targeting system that can effectively function in eukaryotic cells and be programmed as an antiviral defense. PMID:25918406

  14. A large-scale cryoelectronic system for biological sample banking

    NASA Astrophysics Data System (ADS)

    Shirley, Stephen G.; Durst, Christopher H. P.; Fuchs, Christian C.; Zimmermann, Heiko; Ihmig, Frank R.

    2009-11-01

    We describe a polymorphic electronic infrastructure for managing biological samples stored over liquid nitrogen. As part of this system we have developed new cryocontainers and carrier plates attached to Flash memory chips to have a redundant and portable set of data at each sample. Our experimental investigations show that basic Flash operation and endurance is adequate for the application down to liquid nitrogen temperatures. This identification technology can provide the best sample identification, documentation and tracking that brings added value to each sample. The first application of the system is in a worldwide collaborative research towards the production of an AIDS vaccine. The functionality and versatility of the system can lead to an essential optimization of sample and data exchange for global clinical studies.

  15. UT Biomedical Informatics Lab (BMIL) probability wheel

    NASA Astrophysics Data System (ADS)

    Huang, Sheng-Cheng; Lee, Sara; Wang, Allen; Cantor, Scott B.; Sun, Clement; Fan, Kaili; Reece, Gregory P.; Kim, Min Soon; Markey, Mia K.

    A probability wheel app is intended to facilitate communication between two people, an "investigator" and a "participant", about uncertainties inherent in decision-making. Traditionally, a probability wheel is a mechanical prop with two colored slices. A user adjusts the sizes of the slices to indicate the relative value of the probabilities assigned to them. A probability wheel can improve the adjustment process and attenuate the effect of anchoring bias when it is used to estimate or communicate probabilities of outcomes. The goal of this work was to develop a mobile application of the probability wheel that is portable, easily available, and more versatile. We provide a motivating example from medical decision-making, but the tool is widely applicable for researchers in the decision sciences.

  16. Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis.

    PubMed

    Shemesh, Jonathan; Ben Arye, Tom; Avesar, Jonathan; Kang, Joo H; Fine, Amir; Super, Michael; Meller, Amit; Ingber, Donald E; Levenberg, Shulamit

    2014-08-05

    Microfluidic water-in-oil droplets that serve as separate, chemically isolated compartments can be applied for single-cell analysis; however, to investigate encapsulated cells effectively over prolonged time periods, an array of droplets must remain stationary on a versatile substrate for optimal cell compatibility. We present here a platform of unique geometry and substrate versatility that generates a stationary nanodroplet array by using wells branching off a main microfluidic channel. These droplets are confined by multiple sides of a nanowell and are in direct contact with a biocompatible substrate of choice. The device is operated by a unique and reversed loading procedure that eliminates the need for fine pressure control or external tubing. Fluorocarbon oil isolates the droplets and provides soluble oxygen for the cells. By using this approach, the metabolic activity of single adherent cells was monitored continuously over time, and the concentration of viable pathogens in blood-derived samples was determined directly by measuring the number of colony-formed droplets. The method is simple to operate, requires a few microliters of reagent volume, is portable, is reusable, and allows for cell retrieval. This technology may be particularly useful for multiplexed assays for which prolonged and simultaneous visual inspection of many isolated single adherent or nonadherent cells is required.

  17. Compact characterization of liquid absorption and emission spectra using linear variable filters integrated with a CMOS imaging camera.

    PubMed

    Wan, Yuhang; Carlson, John A; Kesler, Benjamin A; Peng, Wang; Su, Patrick; Al-Mulla, Saoud A; Lim, Sung Jun; Smith, Andrew M; Dallesasse, John M; Cunningham, Brian T

    2016-07-08

    A compact analysis platform for detecting liquid absorption and emission spectra using a set of optical linear variable filters atop a CMOS image sensor is presented. The working spectral range of the analysis platform can be extended without a reduction in spectral resolution by utilizing multiple linear variable filters with different wavelength ranges on the same CMOS sensor. With optical setup reconfiguration, its capability to measure both absorption and fluorescence emission is demonstrated. Quantitative detection of fluorescence emission down to 0.28 nM for quantum dot dispersions and 32 ng/mL for near-infrared dyes has been demonstrated on a single platform over a wide spectral range, as well as an absorption-based water quality test, showing the versatility of the system across liquid solutions for different emission and absorption bands. Comparison with a commercially available portable spectrometer and an optical spectrum analyzer shows our system has an improved signal-to-noise ratio and acceptable spectral resolution for discrimination of emission spectra, and characterization of colored liquid's absorption characteristics generated by common biomolecular assays. This simple, compact, and versatile analysis platform demonstrates a path towards an integrated optical device that can be utilized for a wide variety of applications in point-of-use testing and point-of-care diagnostics.

  18. Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis

    PubMed Central

    Shemesh, Jonathan; Ben Arye, Tom; Avesar, Jonathan; Kang, Joo H.; Fine, Amir; Super, Michael; Meller, Amit; Ingber, Donald E.; Levenberg, Shulamit

    2014-01-01

    Microfluidic water-in-oil droplets that serve as separate, chemically isolated compartments can be applied for single-cell analysis; however, to investigate encapsulated cells effectively over prolonged time periods, an array of droplets must remain stationary on a versatile substrate for optimal cell compatibility. We present here a platform of unique geometry and substrate versatility that generates a stationary nanodroplet array by using wells branching off a main microfluidic channel. These droplets are confined by multiple sides of a nanowell and are in direct contact with a biocompatible substrate of choice. The device is operated by a unique and reversed loading procedure that eliminates the need for fine pressure control or external tubing. Fluorocarbon oil isolates the droplets and provides soluble oxygen for the cells. By using this approach, the metabolic activity of single adherent cells was monitored continuously over time, and the concentration of viable pathogens in blood-derived samples was determined directly by measuring the number of colony-formed droplets. The method is simple to operate, requires a few microliters of reagent volume, is portable, is reusable, and allows for cell retrieval. This technology may be particularly useful for multiplexed assays for which prolonged and simultaneous visual inspection of many isolated single adherent or nonadherent cells is required. PMID:25053808

  19. Simple and Versatile Turbidimetric Monitoring of Bacterial Growth in Liquid Cultures Using a Customized 3D Printed Culture Tube Holder and a Miniaturized Spectrophotometer: Application to Facultative and Strictly Anaerobic Bacteria.

    PubMed

    Maia, Margarida R G; Marques, Sara; Cabrita, Ana R J; Wallace, R John; Thompson, Gertrude; Fonseca, António J M; Oliveira, Hugo M

    2016-01-01

    Here we introduce a novel strategy for turbidimetric monitoring of bacterial growth in liquid culture. The instrumentation comprises a light source, a customized 3D printed culture tube holder and a miniaturized spectrophotometer, connected through optical cables. Due to its small footprint and the possibility to operate with external light, bacterial growth was directly monitored from culture tubes in a simple and versatile fashion. This new portable measurement technique was used to monitor the growth of facultative (Escherichia coli ATCC/25922, and Staphylococcus aureus ATCC/29213) and strictly (Butyrivibrio fibrisolvens JW11, Butyrivibrio proteoclasticus P18, and Propionibacterium acnes DSMZ 1897) anaerobic bacteria. For E. coli and S. aureus, the growth rates calculated from normalized optical density values were compared with those ones obtained using a benchtop spectrophotometer without significant differences (P = 0.256). For the strictly anaerobic species, a high precision (relative standard deviation < 3.5%) was observed between replicates up to 48 h. Regarding its potential for customization, this manifold could accommodate further developments for customized turbidimetric monitoring, such as the use of light-emitting diodes as a light source or flow cells.

  20. Simple and Versatile Turbidimetric Monitoring of Bacterial Growth in Liquid Cultures Using a Customized 3D Printed Culture Tube Holder and a Miniaturized Spectrophotometer: Application to Facultative and Strictly Anaerobic Bacteria

    PubMed Central

    Maia, Margarida R. G.; Marques, Sara; Cabrita, Ana R. J.; Wallace, R. John; Thompson, Gertrude; Fonseca, António J. M.; Oliveira, Hugo M.

    2016-01-01

    Here we introduce a novel strategy for turbidimetric monitoring of bacterial growth in liquid culture. The instrumentation comprises a light source, a customized 3D printed culture tube holder and a miniaturized spectrophotometer, connected through optical cables. Due to its small footprint and the possibility to operate with external light, bacterial growth was directly monitored from culture tubes in a simple and versatile fashion. This new portable measurement technique was used to monitor the growth of facultative (Escherichia coli ATCC/25922, and Staphylococcus aureus ATCC/29213) and strictly (Butyrivibrio fibrisolvens JW11, Butyrivibrio proteoclasticus P18, and Propionibacterium acnes DSMZ 1897) anaerobic bacteria. For E. coli and S. aureus, the growth rates calculated from normalized optical density values were compared with those ones obtained using a benchtop spectrophotometer without significant differences (P = 0.256). For the strictly anaerobic species, a high precision (relative standard deviation < 3.5%) was observed between replicates up to 48 h. Regarding its potential for customization, this manifold could accommodate further developments for customized turbidimetric monitoring, such as the use of light-emitting diodes as a light source or flow cells. PMID:27630632

  1. DStat: A Versatile, Open-Source Potentiostat for Electroanalysis and Integration.

    PubMed

    Dryden, Michael D M; Wheeler, Aaron R

    2015-01-01

    Most electroanalytical techniques require the precise control of the potentials in an electrochemical cell using a potentiostat. Commercial potentiostats function as "black boxes," giving limited information about their circuitry and behaviour which can make development of new measurement techniques and integration with other instruments challenging. Recently, a number of lab-built potentiostats have emerged with various design goals including low manufacturing cost and field-portability, but notably lacking is an accessible potentiostat designed for general lab use, focusing on measurement quality combined with ease of use and versatility. To fill this gap, we introduce DStat (http://microfluidics.utoronto.ca/dstat), an open-source, general-purpose potentiostat for use alone or integrated with other instruments. DStat offers picoampere current measurement capabilities, a compact USB-powered design, and user-friendly cross-platform software. DStat is easy and inexpensive to build, may be modified freely, and achieves good performance at low current levels not accessible to other lab-built instruments. In head-to-head tests, DStat's voltammetric measurements are much more sensitive than those of "CheapStat" (a popular open-source potentiostat described previously), and are comparable to those of a compact commercial "black box" potentiostat. Likewise, in head-to-head tests, DStat's potentiometric precision is similar to that of a commercial pH meter. Most importantly, the versatility of DStat was demonstrated through integration with the open-source DropBot digital microfluidics platform. In sum, we propose that DStat is a valuable contribution to the "open source" movement in analytical science, which is allowing users to adapt their tools to their experiments rather than alter their experiments to be compatible with their tools.

  2. DStat: A Versatile, Open-Source Potentiostat for Electroanalysis and Integration

    PubMed Central

    Dryden, Michael D. M.; Wheeler, Aaron R.

    2015-01-01

    Most electroanalytical techniques require the precise control of the potentials in an electrochemical cell using a potentiostat. Commercial potentiostats function as “black boxes,” giving limited information about their circuitry and behaviour which can make development of new measurement techniques and integration with other instruments challenging. Recently, a number of lab-built potentiostats have emerged with various design goals including low manufacturing cost and field-portability, but notably lacking is an accessible potentiostat designed for general lab use, focusing on measurement quality combined with ease of use and versatility. To fill this gap, we introduce DStat (http://microfluidics.utoronto.ca/dstat), an open-source, general-purpose potentiostat for use alone or integrated with other instruments. DStat offers picoampere current measurement capabilities, a compact USB-powered design, and user-friendly cross-platform software. DStat is easy and inexpensive to build, may be modified freely, and achieves good performance at low current levels not accessible to other lab-built instruments. In head-to-head tests, DStat’s voltammetric measurements are much more sensitive than those of “CheapStat” (a popular open-source potentiostat described previously), and are comparable to those of a compact commercial “black box” potentiostat. Likewise, in head-to-head tests, DStat’s potentiometric precision is similar to that of a commercial pH meter. Most importantly, the versatility of DStat was demonstrated through integration with the open-source DropBot digital microfluidics platform. In sum, we propose that DStat is a valuable contribution to the “open source” movement in analytical science, which is allowing users to adapt their tools to their experiments rather than alter their experiments to be compatible with their tools. PMID:26510100

  3. A multimodal interface for real-time soldier-robot teaming

    NASA Astrophysics Data System (ADS)

    Barber, Daniel J.; Howard, Thomas M.; Walter, Matthew R.

    2016-05-01

    Recent research and advances in robotics have led to the development of novel platforms leveraging new sensing capabilities for semantic navigation. As these systems becoming increasingly more robust, they support highly complex commands beyond direct teleoperation and waypoint finding facilitating a transition away from robots as tools to robots as teammates. Supporting future Soldier-Robot teaming requires communication capabilities on par with human-human teams for successful integration of robots. Therefore, as robots increase in functionality, it is equally important that the interface between the Soldier and robot advances as well. Multimodal communication (MMC) enables human-robot teaming through redundancy and levels of communications more robust than single mode interaction. Commercial-off-the-shelf (COTS) technologies released in recent years for smart-phones and gaming provide tools for the creation of portable interfaces incorporating MMC through the use of speech, gestures, and visual displays. However, for multimodal interfaces to be successfully used in the military domain, they must be able to classify speech, gestures, and process natural language in real-time with high accuracy. For the present study, a prototype multimodal interface supporting real-time interactions with an autonomous robot was developed. This device integrated COTS Automated Speech Recognition (ASR), a custom gesture recognition glove, and natural language understanding on a tablet. This paper presents performance results (e.g. response times, accuracy) of the integrated device when commanding an autonomous robot to perform reconnaissance and surveillance activities in an unknown outdoor environment.

  4. Highly Selective and Rapid Breath Isoprene Sensing Enabled by Activated Alumina Filter.

    PubMed

    van den Broek, Jan; Güntner, Andreas T; Pratsinis, Sotiris E

    2018-03-23

    Isoprene is a versatile breath marker for noninvasive monitoring of high blood cholesterol levels as well as for influenza, end-stage renal disease, muscle activity, lung cancer, and liver disease with advanced fibrosis. Its selective detection in complex human breath by portable devices (e.g., metal-oxide gas sensors), however, is still challenging. Here, we present a new filter concept based on activated alumina powder enabling fast and highly selective detection of isoprene at the ppb level and high humidity. The filter contains high surface area adsorbents that retain hydrophilic compounds (e.g., ketones, alcohols, ammonia) representing major interferants in breath while hydrophobic isoprene is not affected. As a proof-of-concept, filters of commercial activated alumina powder are combined with highly sensitive but rather nonspecific, nanostructured Pt-doped SnO 2 sensors. This results in fast (10 s) measurement of isoprene down to 5 ppb at 90% relative humidity with outstanding selectivity (>100) to breath-relevant acetone, ammonia, ethanol, and methanol, superior to state-of-the-art isoprene sensors. Most importantly, when exposed continuously to simulated breath mixtures (four analytes) for 8 days, this filter-sensor system showed stable performance. It can be incorporated readily into a portable breath isoprene analyzer promising for simple-in-use monitoring of blood cholesterol or other patho/physiological conditions.

  5. A Field-Portable Cell Analyzer without a Microscope and Reagents

    PubMed Central

    Oh, Sangwoo; Lee, Moonjin; Hwang, Yongha

    2017-01-01

    This paper demonstrates a commercial-level field-portable lens-free cell analyzer called the NaviCell (No-stain and Automated Versatile Innovative cell analyzer) capable of automatically analyzing cell count and viability without employing an optical microscope and reagents. Based on the lens-free shadow imaging technique, the NaviCell (162 × 135 × 138 mm3 and 1.02 kg) has the advantage of providing analysis results with improved standard deviation between measurement results, owing to its large field of view. Importantly, the cell counting and viability testing can be analyzed without the use of any reagent, thereby simplifying the measurement procedure and reducing potential errors during sample preparation. In this study, the performance of the NaviCell for cell counting and viability testing was demonstrated using 13 and six cell lines, respectively. Based on the results of the hemocytometer (de facto standard), the error rate (ER) and coefficient of variation (CV) of the NaviCell are approximately 3.27 and 2.16 times better than the commercial cell counter, respectively. The cell viability testing of the NaviCell also showed an ER and CV performance improvement of 5.09 and 1.8 times, respectively, demonstrating sufficient potential in the field of cell analysis. PMID:29286336

  6. A Format for Phylogenetic Placements

    PubMed Central

    Matsen, Frederick A.; Hoffman, Noah G.; Gallagher, Aaron; Stamatakis, Alexandros

    2012-01-01

    We have developed a unified format for phylogenetic placements, that is, mappings of environmental sequence data (e.g., short reads) into a phylogenetic tree. We are motivated to do so by the growing number of tools for computing and post-processing phylogenetic placements, and the lack of an established standard for storing them. The format is lightweight, versatile, extensible, and is based on the JSON format, which can be parsed by most modern programming languages. Our format is already implemented in several tools for computing and post-processing parsimony- and likelihood-based phylogenetic placements and has worked well in practice. We believe that establishing a standard format for analyzing read placements at this early stage will lead to a more efficient development of powerful and portable post-analysis tools for the growing applications of phylogenetic placement. PMID:22383988

  7. A format for phylogenetic placements.

    PubMed

    Matsen, Frederick A; Hoffman, Noah G; Gallagher, Aaron; Stamatakis, Alexandros

    2012-01-01

    We have developed a unified format for phylogenetic placements, that is, mappings of environmental sequence data (e.g., short reads) into a phylogenetic tree. We are motivated to do so by the growing number of tools for computing and post-processing phylogenetic placements, and the lack of an established standard for storing them. The format is lightweight, versatile, extensible, and is based on the JSON format, which can be parsed by most modern programming languages. Our format is already implemented in several tools for computing and post-processing parsimony- and likelihood-based phylogenetic placements and has worked well in practice. We believe that establishing a standard format for analyzing read placements at this early stage will lead to a more efficient development of powerful and portable post-analysis tools for the growing applications of phylogenetic placement.

  8. CFD Analysis and Design Optimization Using Parallel Computers

    NASA Technical Reports Server (NTRS)

    Martinelli, Luigi; Alonso, Juan Jose; Jameson, Antony; Reuther, James

    1997-01-01

    A versatile and efficient multi-block method is presented for the simulation of both steady and unsteady flow, as well as aerodynamic design optimization of complete aircraft configurations. The compressible Euler and Reynolds Averaged Navier-Stokes (RANS) equations are discretized using a high resolution scheme on body-fitted structured meshes. An efficient multigrid implicit scheme is implemented for time-accurate flow calculations. Optimum aerodynamic shape design is achieved at very low cost using an adjoint formulation. The method is implemented on parallel computing systems using the MPI message passing interface standard to ensure portability. The results demonstrate that, by combining highly efficient algorithms with parallel computing, it is possible to perform detailed steady and unsteady analysis as well as automatic design for complex configurations using the present generation of parallel computers.

  9. Laser Induced Breakdown Spectroscopy for Elemental Analysis in Environmental, Cultural Heritage and Space Applications: A Review of Methods and Results

    PubMed Central

    Gaudiuso, Rosalba; Dell’Aglio, Marcella; De Pascale, Olga; Senesi, Giorgio S.; De Giacomo, Alessandro

    2010-01-01

    Analytical applications of Laser Induced Breakdown Spectroscopy (LIBS), namely optical emission spectroscopy of laser-induced plasmas, have been constantly growing thanks to its intrinsic conceptual simplicity and versatility. Qualitative and quantitative analysis can be performed by LIBS both by drawing calibration lines and by using calibration-free methods and some of its features, so as fast multi-elemental response, micro-destructiveness, instrumentation portability, have rendered it particularly suitable for analytical applications in the field of environmental science, space exploration and cultural heritage. This review reports and discusses LIBS achievements in these areas and results obtained for soils and aqueous samples, meteorites and terrestrial samples simulating extraterrestrial planets, and cultural heritage samples, including buildings and objects of various kinds. PMID:22163611

  10. Laser induced breakdown spectroscopy for elemental analysis in environmental, cultural heritage and space applications: a review of methods and results.

    PubMed

    Gaudiuso, Rosalba; Dell'Aglio, Marcella; De Pascale, Olga; Senesi, Giorgio S; De Giacomo, Alessandro

    2010-01-01

    Analytical applications of Laser Induced Breakdown Spectroscopy (LIBS), namely optical emission spectroscopy of laser-induced plasmas, have been constantly growing thanks to its intrinsic conceptual simplicity and versatility. Qualitative and quantitative analysis can be performed by LIBS both by drawing calibration lines and by using calibration-free methods and some of its features, so as fast multi-elemental response, micro-destructiveness, instrumentation portability, have rendered it particularly suitable for analytical applications in the field of environmental science, space exploration and cultural heritage. This review reports and discusses LIBS achievements in these areas and results obtained for soils and aqueous samples, meteorites and terrestrial samples simulating extraterrestrial planets, and cultural heritage samples, including buildings and objects of various kinds.

  11. NASA Tech Briefs, November 2010

    NASA Technical Reports Server (NTRS)

    2010-01-01

    Topics covered include: Portable Handheld Optical Window Inspection Device; Salience Assignment for Multiple-Instance Data and Its Application to Crop Yield Prediction; Speech Acquisition and Automatic Speech Recognition for Integrated Spacesuit Audio Systems ; Predicting Long-Range Traversability from Short-Range Stereo-Derived Geometry; Browser-Based Application for Telemetry Monitoring of Robotic Assets; Miniature Low-Noise G-Band I-Q Receiver; Methods of Using a Magnetic Field Response Sensor Within Closed, Electrically Conductive Containers; Differential Resonant Ring YIG Tuned Oscillator; Microfabricated Segmented-Involute-Foil Regenerator for Stirling Engines; Reducing Seal Adhesion in Low Impact Docking Systems; Optimal Flow Control Design; Corrosion-Resistant Container for Molten-Material Processing; Reusable Hot-Wire Cable Cutter; Deployment of a Curved Truss; High-Volume Airborne Fluids Handling Technologies to Fight Wildfires; Modeling of Alkane Oxidation Using Constituents and Species; Fabrication of Lanthanum Telluride 14-1-11 Zintl High-Temperature Thermoelectric Couple; A Computer Model for Analyzing Volatile Removal Assembly; Analysis of Nozzle Jet Plume Effects on Sonic Boom Signature; Optical Sidebands Multiplier; Single Spatial-Mode Room-Temperature-Operated 3.0 to 3.4 micrometer Diode Lasers; Self-Nulling Beam Combiner Using No External Phase Inverter; Portable Dew Point Mass Spectrometry System for Real-Time Gas and Moisture Analysis; Maximum Likelihood Time-of-Arrival Estimation of Optical Pulses via Photon-Counting Photodetectors; Handheld White Light Interferometer for Measuring Defect Depth in Windows; Decomposition Algorithm for Global Reachability on a Time-Varying Graph; Autonomous GN and C for Spacecraft Exploration of Comets and Asteroids; Efficient Web Services Policy Combination; Using CTX Image Features to Predict HiRISE-Equivalent Rock Density; Isolation of the Paenibacillus phoenicis, a Spore-Forming Bacterium; Monolithically Integrated, Mechanically Resilient Carbon-Based Probes for Scanning Probe Microscopy; Cell Radiation Experiment System; Process to Produce Iron Nanoparticle Lunar Dust Simulant Composite; Inversion Method for Early Detection of ARES-1 Case Breach Failure; Use of ILTV Control Laws for LaNCETS Flight Research;and Evaluating Descent and Ascent Trajectories Near Non-Spherical Bodies.

  12. Elastic airtight container for the compaction of air-sensitive materials

    NASA Astrophysics Data System (ADS)

    Shoulders, W. Taylor; Locke, Richard; Gaume, Romain M.

    2016-06-01

    We report on the design and fabrication of a simple and versatile elastic canister for the compaction and hot-pressing of air-sensitive materials. This device consists of a heated double-ended floating die assembly, enclosed in a compressible stainless steel bellows that allows the action of an external hydraulic press in a uniaxial motion. The enclosure is fitted with vacuum, gas, and electrical feedthroughs to allow for atmosphere control, heating, and in situ process monitoring. The overall chamber is compact enough to be portable and transferrable into and out of a standard laboratory glovebox, thus eliminating the problem of exposing samples to ambient atmosphere during loading and unloading. Our design has been tested up to 600 °C and 7500 kg-force applied load, conditions within which transparent ceramics of anhydrous halides can be produced.

  13. Portable system for temperature monitoring in all phases of wine production.

    PubMed

    Boquete, Luciano; Cambralla, Rafael; Rodríguez-Ascariz, J M; Miguel-Jiménez, J M; Cantos-Frontela, J J; Dongil, J

    2010-07-01

    This paper presents a low-cost and highly versatile temperature-monitoring system applicable to all phases of wine production, from grape cultivation through to delivery of bottled wine to the end customer. Monitoring is performed by a purpose-built electronic system comprising a digital memory that stores temperature data and a ZigBee communication system that transmits it to a Control Centre for processing and display. The system has been tested under laboratory conditions and in real-world operational applications. One of the system's advantages is that it can be applied to every phase of wine production. Moreover, with minimum modification, other variables of interest (pH, humidity, etc.) could also be monitored and the system could be applied to other similar sectors, such as olive-oil production. 2010 ISA. Published by Elsevier Ltd. All rights reserved.

  14. Compact characterization of liquid absorption and emission spectra using linear variable filters integrated with a CMOS imaging camera

    PubMed Central

    Wan, Yuhang; Carlson, John A.; Kesler, Benjamin A.; Peng, Wang; Su, Patrick; Al-Mulla, Saoud A.; Lim, Sung Jun; Smith, Andrew M.; Dallesasse, John M.; Cunningham, Brian T.

    2016-01-01

    A compact analysis platform for detecting liquid absorption and emission spectra using a set of optical linear variable filters atop a CMOS image sensor is presented. The working spectral range of the analysis platform can be extended without a reduction in spectral resolution by utilizing multiple linear variable filters with different wavelength ranges on the same CMOS sensor. With optical setup reconfiguration, its capability to measure both absorption and fluorescence emission is demonstrated. Quantitative detection of fluorescence emission down to 0.28 nM for quantum dot dispersions and 32 ng/mL for near-infrared dyes has been demonstrated on a single platform over a wide spectral range, as well as an absorption-based water quality test, showing the versatility of the system across liquid solutions for different emission and absorption bands. Comparison with a commercially available portable spectrometer and an optical spectrum analyzer shows our system has an improved signal-to-noise ratio and acceptable spectral resolution for discrimination of emission spectra, and characterization of colored liquid’s absorption characteristics generated by common biomolecular assays. This simple, compact, and versatile analysis platform demonstrates a path towards an integrated optical device that can be utilized for a wide variety of applications in point-of-use testing and point-of-care diagnostics. PMID:27389070

  15. Compact characterization of liquid absorption and emission spectra using linear variable filters integrated with a CMOS imaging camera

    NASA Astrophysics Data System (ADS)

    Wan, Yuhang; Carlson, John A.; Kesler, Benjamin A.; Peng, Wang; Su, Patrick; Al-Mulla, Saoud A.; Lim, Sung Jun; Smith, Andrew M.; Dallesasse, John M.; Cunningham, Brian T.

    2016-07-01

    A compact analysis platform for detecting liquid absorption and emission spectra using a set of optical linear variable filters atop a CMOS image sensor is presented. The working spectral range of the analysis platform can be extended without a reduction in spectral resolution by utilizing multiple linear variable filters with different wavelength ranges on the same CMOS sensor. With optical setup reconfiguration, its capability to measure both absorption and fluorescence emission is demonstrated. Quantitative detection of fluorescence emission down to 0.28 nM for quantum dot dispersions and 32 ng/mL for near-infrared dyes has been demonstrated on a single platform over a wide spectral range, as well as an absorption-based water quality test, showing the versatility of the system across liquid solutions for different emission and absorption bands. Comparison with a commercially available portable spectrometer and an optical spectrum analyzer shows our system has an improved signal-to-noise ratio and acceptable spectral resolution for discrimination of emission spectra, and characterization of colored liquid’s absorption characteristics generated by common biomolecular assays. This simple, compact, and versatile analysis platform demonstrates a path towards an integrated optical device that can be utilized for a wide variety of applications in point-of-use testing and point-of-care diagnostics.

  16. Design and operation of a portable scanner for high performance microchip capillary array electrophoresis.

    PubMed

    Scherer, James R; Liu, Peng; Mathies, Richard A

    2010-11-01

    We have developed a compact, laser-induced fluorescence detection scanner, the multichannel capillary array electrophoresis portable scanner (McCAEPs) as a platform for electrophoretic detection and control of high-throughput, integrated microfluidic devices for genetic and other analyses. The instrument contains a confocal optical system with a rotary objective for detecting four different fluorescence signals, a pneumatic system consisting of two pressure/vacuum pumps and 28 individual addressable solenoid valves for control of on-chip microvalves and micropumps, four Polymerase Chain Reaction (PCR) temperature control systems, and four high voltage power supplies for electrophoresis. The detection limit of the instrument is ~20 pM for on-chip capillary electrophoresis of fluorescein dyes. To demonstrate the system performance for forensic short tandem repeat (STR) analysis, two experiments were conducted: (i) electrophoretic separation and detection of STR samples on a 96-lane microfabricated capillary array electrophoresis microchip. Fully resolved PowerPlex(®) 16 STR profiles amplified from 1 ng of 9947A female standard DNA were successfully obtained; (ii) nine-plex STR amplification, sample injection, separation, and fluorescence detection of 100-copy 9948 male standard DNA in a single integrated PCR- capillary electrophoresis microchip. These results demonstrate that the McCAEPs can be used as a versatile control and detection instrument that operates integrated microfluidic devices for high-performance forensic human identification.

  17. Design and operation of a portable scanner for high performance microchip capillary array electrophoresis

    NASA Astrophysics Data System (ADS)

    Scherer, James R.; Liu, Peng; Mathies, Richard A.

    2010-11-01

    We have developed a compact, laser-induced fluorescence detection scanner, the multichannel capillary array electrophoresis portable scanner (McCAEPs) as a platform for electrophoretic detection and control of high-throughput, integrated microfluidic devices for genetic and other analyses. The instrument contains a confocal optical system with a rotary objective for detecting four different fluorescence signals, a pneumatic system consisting of two pressure/vacuum pumps and 28 individual addressable solenoid valves for control of on-chip microvalves and micropumps, four Polymerase Chain Reaction (PCR) temperature control systems, and four high voltage power supplies for electrophoresis. The detection limit of the instrument is ˜20 pM for on-chip capillary electrophoresis of fluorescein dyes. To demonstrate the system performance for forensic short tandem repeat (STR) analysis, two experiments were conducted: (i) electrophoretic separation and detection of STR samples on a 96-lane microfabricated capillary array electrophoresis microchip. Fully resolved PowerPlex® 16 STR profiles amplified from 1 ng of 9947A female standard DNA were successfully obtained; (ii) nine-plex STR amplification, sample injection, separation, and fluorescence detection of 100-copy 9948 male standard DNA in a single integrated PCR- capillary electrophoresis microchip. These results demonstrate that the McCAEPs can be used as a versatile control and detection instrument that operates integrated microfluidic devices for high-performance forensic human identification.

  18. Enhanced Software for Scheduling Space-Shuttle Processing

    NASA Technical Reports Server (NTRS)

    Barretta, Joseph A.; Johnson, Earl P.; Bierman, Rocky R.; Blanco, Juan; Boaz, Kathleen; Stotz, Lisa A.; Clark, Michael; Lebovitz, George; Lotti, Kenneth J.; Moody, James M.; hide

    2004-01-01

    The Ground Processing Scheduling System (GPSS) computer program is used to develop streamlined schedules for the inspection, repair, and refurbishment of space shuttles at Kennedy Space Center. A scheduling computer program is needed because space-shuttle processing is complex and it is frequently necessary to modify schedules to accommodate unanticipated events, unavailability of specialized personnel, unexpected delays, and the need to repair newly discovered defects. GPSS implements constraint-based scheduling algorithms and provides an interactive scheduling software environment. In response to inputs, GPSS can respond with schedules that are optimized in the sense that they contain minimal violations of constraints while supporting the most effective and efficient utilization of space-shuttle ground processing resources. The present version of GPSS is a product of re-engineering of a prototype version. While the prototype version proved to be valuable and versatile as a scheduling software tool during the first five years, it was characterized by design and algorithmic deficiencies that affected schedule revisions, query capability, task movement, report capability, and overall interface complexity. In addition, the lack of documentation gave rise to difficulties in maintenance and limited both enhanceability and portability. The goal of the GPSS re-engineering project was to upgrade the prototype into a flexible system that supports multiple- flow, multiple-site scheduling and that retains the strengths of the prototype while incorporating improvements in maintainability, enhanceability, and portability.

  19. Pediatric awake craniotomy and intra-operative stimulation mapping.

    PubMed

    Balogun, James A; Khan, Osaama H; Taylor, Michael; Dirks, Peter; Der, Tara; Carter Snead Iii, O; Weiss, Shelly; Ochi, Ayako; Drake, James; Rutka, James T

    2014-11-01

    The indications for operating on lesions in or near areas of cortical eloquence balance the benefit of resection with the risk of permanent neurological deficit. In adults, awake craniotomy has become a versatile tool in tumor, epilepsy and functional neurosurgery, permitting intra-operative stimulation mapping particularly for language, sensory and motor cortical pathways. This allows for maximal tumor resection with considerable reduction in the risk of post-operative speech and motor deficits. We report our experience of awake craniotomy and cortical stimulation for epilepsy and supratentorial tumors located in and around eloquent areas in a pediatric population (n=10, five females). The presenting symptom was mainly seizures and all children had normal neurological examinations. Neuroimaging showed lesions in the left opercular (n=4) and precentral or peri-sylvian regions (n=6). Three right-sided and seven left-sided awake craniotomies were performed. Two patients had a history of prior craniotomy. All patients had intra-operative mapping for either speech or motor or both using cortical stimulation. The surgical goal for tumor patients was gross total resection, while for all epilepsy procedures, focal cortical resections were completed without any difficulty. None of the patients had permanent post-operative neurologic deficits. The patient with an epileptic focus over the speech area in the left frontal lobe had a mild word finding difficulty post-operatively but this improved progressively. Follow-up ranged from 6 to 27 months. Pediatric awake craniotomy with intra-operative mapping is a precise, safe and reliable method allowing for resection of lesions in eloquent areas. Further validations on larger number of patients will be needed to verify the utility of this technique in the pediatric population. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Clinical Applications of Near-infrared Diffuse Correlation Spectroscopy and Tomography for Tissue Blood Flow Monitoring and Imaging

    PubMed Central

    Shang, Yu; Li, Ting; Yu, Guoqiang

    2017-01-01

    Blood flow is one such available observable promoting a wealth of physiological insight both individually and in combination with other metrics. Near-infrared diffuse correlation spectroscopy (DCS) and, to a lesser extent, diffuse correlation tomography (DCT), have increasingly received interest over the past decade as noninvasive methods for tissue blood flow measurements and imaging. DCS/DCT offers several attractive features for tissue blood flow measurements/imaging such as noninvasiveness, portability, high temporal resolution, and relatively large penetration depth (up to several centimeters). This review first introduces the basic principle and instrumentation of DCS/DCT, followed by presenting clinical application examples of DCS/DCT for the diagnosis and therapeutic monitoring of diseases in a variety of organs/tissues including brain, skeletal muscle, and tumor. Clinical study results demonstrate technical versatility of DCS/DCT in providing important information for disease diagnosis and intervention monitoring. PMID:28199219

  1. Fast and accurate detection of cancer cell using a versatile three-channel plasmonic sensor

    NASA Astrophysics Data System (ADS)

    Hoseinian, M.; Ahmadi, A. R.; Bolorizadeh, M. A.

    2016-09-01

    Surface Plasmon Resonance (SPR) optical fiber sensors can be used as cost-effective small sized biosensors that are relatively simple to operate. Additionally, these instruments are label-free, hence rendering them highly sensitive to biological measurements. In this study, a three-channel microstructure optical fiber plasmonic-based portable biosensor is designed and analyzed using Finite Element Method. The proposed system is capable of determining changes in sample's refractive index with precision of order one thousandth. The biosensor measures three absorption resonance wavelengths of the analytes simultaneously. This property is one of the main advantages of the proposed biosensor since it reduces the error in the measured wavelength and enhances the accuracy of the results up to 10-5 m/RIU by reducing noise. In this paper, Jurkat cell, an indicator cell for leukemia cancer, is considered as the analyte; and its absorption resonance wavelengths as well as sensitivity in each channel are determined.

  2. Ultrasound: medical imaging and beyond (an invited review).

    PubMed

    Azhari, Haim

    2012-09-01

    Medical applications of ultrasound were first investigated about seventy years ago. It has rapidly evolved since then, becoming an essential tool in medical imaging. Ultrasound ability to provide real time images with frame rates exceeding several hundred frames per second allows one to view rapid anatomical changes as well as to guide minimal invasive procedures. By, combining Doppler techniques with anatomical images ultrasound provides real time quantitative flow information as well. It is portable, versatile, cost effective and considered sufficiently hazardless to monitor pregnancy. Moreover, ultrasound has the unique capacity to offer therapeutic capabilities in addition to its outstanding imaging abilities. It can be used for physiotherapy, lithotripsy, and thermal ablation, and recent studies have demonstrated its usefulness in drug delivery, gene therapy and molecular imaging. The purpose of this article is to provide an introductory review of the field covering briefly topics from basic physics through current imaging methods to therapeutic applications.

  3. Development of a data acquisition system using a RISC/UNIX TM workstation

    NASA Astrophysics Data System (ADS)

    Takeuchi, Y.; Tanimori, T.; Yasu, Y.

    1993-05-01

    We have developed a compact data acquisition system on RISC/UNIX workstations. A SUN TM SPARCstation TM IPC was used, in which an extension bus "SBus TM" was linked to a VMEbus. The transfer rate achieved was better than 7 Mbyte/s between the VMEbus and the SUN. A device driver for CAMAC was developed in order to realize an interruptive feature in UNIX. In addition, list processing has been incorporated in order to keep the high priority of the data handling process in UNIX. The successful developments of both device driver and list processing have made it possible to realize the good real-time feature on the RISC/UNIX system. Based on this architecture, a portable and versatile data taking system has been developed, which consists of a graphical user interface, I/O handler, user analysis process, process manager and a CAMAC device driver.

  4. "Cut-and-paste" manufacture of multiparametric epidermal electronic systems

    NASA Astrophysics Data System (ADS)

    Lu, Nanshu; Yang, Shixuan; Wang, Pulin

    2016-05-01

    Epidermal electronics is a class of noninvasive and unobstructive skin-mounted, tattoo-like sensors and electronics capable of vital sign monitoring and establishing human-machine interface. The high cost of manpower, materials, vacuum equipment, and photolithographic facilities associated with its manufacture greatly hinders the widespread use of disposable epidermal electronics. Here we report a cost and time effective, completely dry, benchtop "cut-and-paste" method for the freeform and portable manufacture of multiparametric epidermal sensor systems (ESS) within minutes. This versatile method works for all types of thin metal and polymeric sheets and is compatible with any tattoo adhesives or medical tapes. The resulting ESS are multimaterial and multifunctional and have been demonstrated to noninvasively but accurately measure electrophysiological signals, skin temperature, skin hydration, as well as respiratory rate. In addition, planar stretchable coils exploiting double-stranded serpentine design have been successfully applied as wireless, passive epidermal strain sensors.

  5. Generalized platform for antibody detection using the antibody catalyzed water oxidation pathway.

    PubMed

    Welch, M Elizabeth; Ritzert, Nicole L; Chen, Hongjun; Smith, Norah L; Tague, Michele E; Xu, Youyong; Baird, Barbara A; Abruña, Héctor D; Ober, Christopher K

    2014-02-05

    Infectious diseases, such as influenza, present a prominent global problem including the constant threat of pandemics that initiate in avian or other species and then pass to humans. We report a new sensor that can be specifically functionalized to detect antibodies associated with a wide range of infectious diseases in multiple species. This biosensor is based on electrochemical detection of hydrogen peroxide generated through the intrinsic catalytic activity of all antibodies: the antibody catalyzed water oxidation pathway (ACWOP). Our platform includes a polymer brush-modified surface where specific antibodies bind to conjugated haptens with high affinity and specificity. Hydrogen peroxide provides an electrochemical signal that is mediated by Resorufin/Amplex Red. We characterize the biosensor platform, using model anti-DNP antibodies, with the ultimate goal of designing a versatile device that is inexpensive, portable, reliable, and fast. We demonstrate detection of antibodies at concentrations that fall well within clinically relevant levels.

  6. Computer Applications in Health Science Education.

    PubMed

    Juanes, Juan A; Ruisoto, Pablo

    2015-09-01

    In recent years, computer application development has experienced exponential growth, not only in the number of publications but also in the scope or contexts that have benefited from its use. In health science training, and medicine specifically, the gradual incorporation of technological developments has transformed the teaching and learning process, resulting in true "educational technology". The goal of this paper is to review the main features involved in these applications and highlight the main lines of research for the future. The results of peer reviewed literature published recently indicate the following features shared by the key technological developments in the field of health science education: first, development of simulation and visualization systems for a more complete and realistic representation of learning material over traditional paper format; second, portability and versatility of the applications, adapted for an increasing number of devices and operative systems; third, increasing focus on open source applications such as Massive Open Online Course (MOOC).

  7. Digital microfluidics: A promising technique for biochemical applications

    NASA Astrophysics Data System (ADS)

    Wang, He; Chen, Liguo; Sun, Lining

    2017-12-01

    Digital microfluidics (DMF) is a versatile microfluidics technology that has significant application potential in the areas of automation and miniaturization. In DMF, discrete droplets containing samples and reagents are controlled to implement a series of operations via electrowetting-on-dielectric. This process works by applying electrical potentials to an array of electrodes coated with a hydrophobic dielectric layer. Unlike microchannels, DMF facilitates precise control over multiple reaction processes without using complex pump, microvalve, and tubing networks. DMF also presents other distinct features, such as portability, less sample consumption, shorter chemical reaction time, flexibility, and easier combination with other technology types. Due to its unique advantages, DMF has been applied to a broad range of fields (e.g., chemistry, biology, medicine, and environment). This study reviews the basic principles of droplet actuation, configuration design, and fabrication of the DMF device, as well as discusses the latest progress in DMF from the biochemistry perspective.

  8. Structure and practices of the video relay service program; telecommunications relay services and speech-to-speech services for individuals with hearing and speech disabilities. Final rule.

    PubMed

    2013-07-05

    In this document, the Commission adopts further measures to improve the structure, efficiency, and quality of the video relay service (VRS) program, reducing the inefficiencies in the program, as well as reducing the risk of waste, fraud, and abuse, and ensuring that the program makes full use of advances in commercially-available technology. These measures involve a fundamental restructuring of the program to support innovation and competition, drive down ratepayer and provider costs, eliminate incentives for waste that have burdened the Telecommunications Relay Services (TRS) Fund in the past, and further protect consumers. The Commission adopts several measures in order to: ensure that VRS users can easily select their provider of choice by promoting the development of interoperability and portability standards; enable consumers to use off-the-shelf devices and deploying a VRS application to work with these devices; create a centralized TRS User Registration Database to ensure VRS user eligibility; encourage competition and innovation in VRS call handling services; spur research and development on VRS services by entering into a Memorandum of Understanding with the National Science Foundation; and pilot a National Outreach Program to educate the general public about relay services. In this document, the Commission also adopts new VRS compensation rates that move these rates toward actual costs over the next four years which will better approximate the actual, reasonable costs of providing VRS, and will reduce the costs of operating the program. The Commission takes these steps to ensure the integrity of the TRS Fund while providing stability and certainty to providers.

  9. A label-free nanostructured plasmonic biosensor based on Blu-ray discs with integrated microfluidics for sensitive biodetection.

    PubMed

    López-Muñoz, Gerardo A; Estevez, M-Carmen; Peláez-Gutierrez, E Cristina; Homs-Corbera, Antoni; García-Hernandez, M Carmen; Imbaud, J Ignacio; Lechuga, Laura M

    2017-10-15

    Nanostructure-based plasmonic biosensors have quickly positioned themselves as interesting candidates for the design of portable optical biosensor platforms considering the potential benefits they can offer in integration, miniaturization, multiplexing, and real-time label-free detection. We have developed a simple integrated nanoplasmonic sensor taking advantage of the periodic nanostructured array of commercial Blu-ray discs. Sensors with two gold film thicknesses (50 and 100nm) were fabricated and optically characterized by varying the oblique-angle of the incident light in optical reflectance measurements. Contrary to the use normal light incidence previously reported with other optical discs, we observed an enhancement in sensitivity and a narrowing of the resonant linewidths as the light incidence angle was increased, which could be related to the generation of Fano resonant modes. The new sensors achieve a figure of merit (FOM) up to 35 RIU -1 and a competitive bulk limit of detection (LOD) of 6.3×10 -6 RIU. These values significantly improve previously reported results obtained with normal light incidence reflectance measurements using similar structures. The sensor has been combined with versatile, simple, ease to-fabricate microfluidics. The integrated chip is only 1cm 2 (including a PDMS flow cell with a 50µm height microfluidic channel fabricated with double-sided adhesive tape) and all the optical components are mounted on a 10cm×10cm portable prototype, illustrating its facile miniaturization, integration and potential portability. Finally, to assess the label-free biosensing capability of the new sensor, we have evaluated the presence of specific antibodies against the GTF2b protein, a tumor-associate antigen (TAA) related to colorectal cancer. We have achieved a LOD in the pM order and have assessed the feasibility of directly measuring biological samples such as human serum. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Metadata Authoring with Versatility and Extensibility

    NASA Technical Reports Server (NTRS)

    Pollack, Janine; Olsen, Lola

    2004-01-01

    NASA's Global Change Master Directory (GCMD) assists the scientific community in the discovery of and linkage to Earth science data sets and related services. The GCMD holds over 13,800 data set descriptions in Directory Interchange Format (DIF) and 700 data service descriptions in Service Entry Resource Format (SERF), encompassing the disciplines of geology, hydrology, oceanography, meteorology, and ecology. Data descriptions also contain geographic coverage information and direct links to the data, thus allowing researchers to discover data pertaining to a geographic location of interest, then quickly acquire those data. The GCMD strives to be the preferred data locator for world-wide directory-level metadata. In this vein, scientists and data providers must have access to intuitive and efficient metadata authoring tools. Existing GCMD tools are attracting widespread usage; however, a need for tools that are portable, customizable and versatile still exists. With tool usage directly influencing metadata population, it has become apparent that new tools are needed to fill these voids. As a result, the GCMD has released a new authoring tool allowing for both web-based and stand-alone authoring of descriptions. Furthermore, this tool incorporates the ability to plug-and-play the metadata format of choice, offering users options of DIF, SERF, FGDC, ISO or any other defined standard. Allowing data holders to work with their preferred format, as well as an option of a stand-alone application or web-based environment, docBUlLDER will assist the scientific community in efficiently creating quality data and services metadata.

  11. WE-FG-BRA-04: A Portable Confocal Microscope to Image Live Cell Damage Response Induced by Therapeutic Radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McFadden, C; Flint, D; Grosshans, D

    Purpose: To construct a custom and portable fluorescence confocal laser-scanning microscope (FCLSM) that can be placed in the path of therapeutic radiation beams to study real-time radiation-induced damage response in live cells. Methods: We designed and constructed a portable FCLSM with three laser diodes for excitation (405, 488, and 635 nm). An objective lens focuses the excitation light and collects fluorescence from the sample. A pair of galvanometer mirrors scans/collects the laser beam/fluorescence along the focal plane (x/y-directions). A stepper motor stage scans in the axial direction and positions the x/y of the image field. Barrier filters and dichroic mirrorsmore » are used to route the spectral emission bands to the appropriate photodetector. An avalanche photodiode collects near-infrared fluorescence; a photodiode collects back-reflected 635 nm light; and a photomultiplier tube collects green fluorescence in the range of eGFP/eYFP. A 200-µm diameter pinhole was used to implement the confocal geometry for near-infrared and red channels and a 150-µm diameter pinhole for the green channel. Data acquisition and system control were achieved using a high-throughput data acquisition card. In-house software developed in LabVIEW was used to control the hardware, collect data from the photodetectors and reconstruct the confocal images. Results: 6 frames/s can be acquired for a 25 µm{sup 2} (128×128 pixels) field of view, visualizing the entire volume of the cell nucleus (∼10 µm depth) in <10 s. To demonstrate the usefulness of our FCLSM, we imaged gold nanoshells in live cells, radiation-induced damage in fibrosarcoma cells expressing eGFP tagged to a DNA repair protein, and neurons expressing eGFP. The system can also image particle tracks in fluorescent nuclear track detectors. Conclusion: We developed a versatile and portable FCLSM that allows radiobiology studies in live cells exposed to therapeutic radiation. The FCLSM can be placed in any vertical beam line for top-to-bottom exposures. This research was supported by the Sister Institution Network Fund and the Center for Radiation Oncology Research at The University of Texas MD Anderson Cancer Center and Cancer Prevention and Research Institute of Texas. Gabriel Sawakuchi has research support from Elekta Inc.« less

  12. Portable microfluidic and smartphone-based devices for monitoring of cardiovascular diseases at the point of care.

    PubMed

    Hu, Jie; Cui, Xingye; Gong, Yan; Xu, Xiayu; Gao, Bin; Wen, Ting; Lu, Tian Jian; Xu, Feng

    2016-01-01

    Cardiovascular diseases (CVDs) are the main causes of morbidity and mortality in the world where about 4 in every 5 CVD deaths happen in low- and middle-income countries (LMICs). Most CVDs are preventable and curable, which is largely dependent on timely and effective interventions, including diagnosis, prognosis and therapeutic monitoring. However, these interventions are high-cost in high income countries and are usually lacking in LMICs. Thanks to the rapid development of microfluidics and nanotechnology, lots of portable analytical devices are developed for detection of CVDs at the point-of-care (POC). In the meantime, smartphone, as a versatile and powerful handheld tool, has been employed not only as a reader for microfluidic assays, but also as an analyzer for physiological indexes. In this review, we present a comprehensive introduction of the current status and potential development direction on POC diagnostics for CVDs. First of all, we introduce some main facts about CVDs and their standard diagnostic procedures and methods. Second, we discuss about both commercially available POC devices and developed prototypes for detection of CVDs via immunoassays. Subsequently, we report the advances in smartphone-based readout for microfluidic assays. Finally, we present some examples using smartphone, individually or combined with other components or devices, for CVD monitoring. We envision an integrated smartphone-based system capable of functioning blood tests, disease examination, and imaging will come in the future. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. A pilot study of comprehensive ultrasound education at the Wayne State University School of Medicine: a pioneer year review.

    PubMed

    Rao, Sishir; van Holsbeeck, Lodewijk; Musial, Joseph L; Parker, Alton; Bouffard, J Antonio; Bridge, Patrick; Jackson, Matt; Dulchavsky, Scott A

    2008-05-01

    Ultrasound is a versatile diagnostic modality used in a variety of medical fields. Wayne State University School of Medicine (WSUSOM) is one of the first medical schools in the United States to integrate an ultrasound curriculum through both basic science courses and clinical clerkships. In 2006, 25 portable ultrasound units were donated to WSUSOM. First-year medical students were provided an ultrasound curriculum consisting of 6 organ-system sessions that addressed the basics of ultrasound techniques, anatomy, and procedural skills. After the last session, students were administered 2 anonymous and voluntary evaluations. The first assessed their overall experience with the ultrasound curriculum, and the second assessed their technical skills in applying ultrasound techniques. Eighty-three percent of students agreed or strongly agreed that their experience with ultrasound education was positive. On the summative evaluation, nearly 91% of students agreed or strongly agreed that they would benefit from continued ultrasound education throughout their 4 years of medical school. Student performance on the technical assessment was also very positive, with mean class performance of 87%. As residency programs adopt ultrasound training, medical school faculty should consider incorporating ultrasound education into their curriculum. Portable ultrasound has the potential to be used in many different settings, including rural practice sites and sporting events. The WSUSOM committee's pilot ultrasound curriculum will continue to use student feedback to enhance the ultrasound experience, helping students prepare for challenges that they will face in the future.

  14. Moving Ahead With Eye Power

    NASA Technical Reports Server (NTRS)

    2002-01-01

    NASA's Jet Propulsion Laboratory's collaborated with LC Technologies, Inc., to improve LCT's Eyegaze Communication System, an eye tracker that enables people with severe cerebral palsy, muscular dystrophy, multiple sclerosis, strokes, brain injuries, spinal cord injuries, and ALS (amyotrophic lateral sclerosis) to communicate and control their environment using their eye movements. To operate the system, the user sits in front of the computer monitor while the camera focuses on one eye. By looking at control keys on the monitor for a fraction of a second, the user can 'talk' with speech synthesis, type, operate a telephone, access the Internet and e-mail, and run computer software. Nothing is attached to the user's head or body, and the improved size and portability allow the system to be mounted on a wheelchair. LCT and JPL are working on several other areas of improvement that have commercial add-on potential.

  15. Northeast Artificial Intelligence Consortium annual report. Volume 2. 1988. Discussing, using, and recognizing plans (NLP). Interim report, January-December 1988

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shapiro, S.C.; Woolf, B.

    The Northeast Artificial Intelligence Consortium (NAIC) was created by the Air Force Systems Command, Rome Air Development Center, and the Office of Scientific Research. Its purpose is to conduct pertinent research in artificial intelligence and to perform activities ancillary to this research. This report describes progress that has been made in the fourth year of the existence of the NAIC on the technical research tasks undertaken at the member universities. The topics covered in general are: versatile expert system for equipment maintenance, distributed AI for communications system control, automatic photointerpretation, time-oriented problem solving, speech understanding systems, knowledge base maintenance, hardwaremore » architectures for very large systems, knowledge-based reasoning and planning, and a knowledge acquisition, assistance, and explanation system. The specific topic for this volume is the recognition of plans expressed in natural language, followed by their discussion and use.« less

  16. Acoustical criteria for hospital patient rooms: Resolving competing requirements

    NASA Astrophysics Data System (ADS)

    Brooks, Bennett M.

    2003-10-01

    The acoustical criteria for patient rooms in hospitals, nursing homes, and rehabilitation facilities may be based on several needs. One important requirement is that noise levels in the room be conducive to restful sleep. Also, caregivers must have easy auditory and visual access to the patients, and be able to hear vital sign monitor alarms. This often means that patient rooms are located near central nurse stations and that patient room doors are left open. Further, the recently published federal privacy standards developed by the U.S. Department of Health and Human Services (HSS) under the Health Insurance Portability and Accountability Act (HIPAA) require that ``appropriate physical safeguards'' be put in place to protect the confidentiality of patient health information. The simultaneous and competing requirements for speech privacy, caregiver access, and good sleeping conditions present a serious acoustical challenge to health care facility designers. Specific facility design issues and potential solution strategies are presented.

  17. SoundView: an auditory guidance system based on environment understanding for the visually impaired people.

    PubMed

    Nie, Min; Ren, Jie; Li, Zhengjun; Niu, Jinhai; Qiu, Yihong; Zhu, Yisheng; Tong, Shanbao

    2009-01-01

    Without visual information, the blind people live in various hardships with shopping, reading, finding objects and etc. Therefore, we developed a portable auditory guide system, called SoundView, for visually impaired people. This prototype system consists of a mini-CCD camera, a digital signal processing unit and an earphone, working with built-in customizable auditory coding algorithms. Employing environment understanding techniques, SoundView processes the images from a camera and detects objects tagged with barcodes. The recognized objects in the environment are then encoded into stereo speech signals for the blind though an earphone. The user would be able to recognize the type, motion state and location of the interested objects with the help of SoundView. Compared with other visual assistant techniques, SoundView is object-oriented and has the advantages of cheap cost, smaller size, light weight, low power consumption and easy customization.

  18. The functional organization of the left STS: a large scale meta-analysis of PET and fMRI studies of healthy adults

    PubMed Central

    Liebenthal, Einat; Desai, Rutvik H.; Humphries, Colin; Sabri, Merav; Desai, Anjali

    2014-01-01

    The superior temporal sulcus (STS) in the left hemisphere is functionally diverse, with sub-areas implicated in both linguistic and non-linguistic functions. However, the number and boundaries of distinct functional regions remain to be determined. Here, we present new evidence, from meta-analysis of a large number of positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) studies, of different functional specificity in the left STS supporting a division of its middle to terminal extent into at least three functional areas. The middle portion of the left STS stem (fmSTS) is highly specialized for speech perception and the processing of language material. The posterior portion of the left STS stem (fpSTS) is highly versatile and involved in multiple functions supporting semantic memory and associative thinking. The fpSTS responds to both language and non-language stimuli but the sensitivity to non-language material is greater. The horizontal portion of the left STS stem and terminal ascending branches (ftSTS) display intermediate functional specificity, with the anterior-dorsal ascending branch (fatSTS) supporting executive functions and motor planning and showing greater sensitivity to language material, and the horizontal stem and posterior-ventral ascending branch (fptSTS) supporting primarily semantic processing and displaying greater sensitivity to non-language material. We suggest that the high functional specificity of the left fmSTS for speech is an important means by which the human brain achieves exquisite affinity and efficiency for native speech perception. In contrast, the extreme multi-functionality of the left fpSTS reflects the role of this area as a cortical hub for semantic processing and the extraction of meaning from multiple sources of information. Finally, in the left ftSTS, further functional differentiation between the dorsal and ventral aspect is warranted. PMID:25309312

  19. An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore.

    PubMed

    Liu, Jiaquan; Hanne, Jeungphill; Britton, Brooke M; Shoffner, Matthew; Albers, Aaron E; Bennett, Jared; Zatezalo, Rachel; Barfield, Robyn; Rabuka, David; Lee, Jong-Bong; Fishel, Richard

    2015-11-19

    Fluorophore labeling of proteins while preserving native functions is essential for bulk Förster resonance energy transfer (FRET) interaction and single molecule imaging analysis. Here we describe a versatile, efficient, specific, irreversible, gentle and low-cost method for labeling proteins with fluorophores that appears substantially more robust than a similar but chemically distinct procedure. The method employs the controlled enzymatic conversion of a central Cys to a reactive formylglycine (fGly) aldehyde within a six amino acid Formylglycine Generating Enzyme (FGE) recognition sequence in vitro. The fluorophore is then irreversibly linked to the fGly residue using a Hydrazinyl-Iso-Pictet-Spengler (HIPS) ligation reaction. We demonstrate the robust large-scale fluorophore labeling and purification of E.coli (Ec) mismatch repair (MMR) components. Fluorophore labeling did not alter the native functions of these MMR proteins in vitro or in singulo. Because the FGE recognition sequence is easily portable, FGE-HIPS fluorophore-labeling may be easily extended to other proteins.

  20. Semiconducting polymers with nanocrystallites interconnected via boron-doped carbon nanotubes.

    PubMed

    Yu, Kilho; Lee, Ju Min; Kim, Junghwan; Kim, Geunjin; Kang, Hongkyu; Park, Byoungwook; Ho Kahng, Yung; Kwon, Sooncheol; Lee, Sangchul; Lee, Byoung Hun; Kim, Jehan; Park, Hyung Il; Kim, Sang Ouk; Lee, Kwanghee

    2014-12-10

    Organic semiconductors are key building blocks for future electronic devices that require unprecedented properties of low-weight, flexibility, and portability. However, the low charge-carrier mobility and undesirable processing conditions limit their compatibility with low-cost, flexible, and printable electronics. Here, we present significantly enhanced field-effect mobility (μ(FET)) in semiconducting polymers mixed with boron-doped carbon nanotubes (B-CNTs). In contrast to undoped CNTs, which tend to form undesired aggregates, the B-CNTs exhibit an excellent dispersion in conjugated polymer matrices and improve the charge transport between polymer chains. Consequently, the B-CNT-mixed semiconducting polymers enable the fabrication of high-performance FETs on plastic substrates via a solution process; the μFET of the resulting FETs reaches 7.2 cm(2) V(-1) s(-1), which is the highest value reported for a flexible FET based on a semiconducting polymer. Our approach is applicable to various semiconducting polymers without any additional undesirable processing treatments, indicating its versatility, universality, and potential for high-performance printable electronics.

  1. Design and experimental validation of Unilateral Linear Halbach magnet arrays for single-sided magnetic resonance.

    PubMed

    Bashyam, Ashvin; Li, Matthew; Cima, Michael J

    2018-07-01

    Single-sided NMR has the potential for broad utility and has found applications in healthcare, materials analysis, food quality assurance, and the oil and gas industry. These sensors require a remote, strong, uniform magnetic field to perform high sensitivity measurements. We demonstrate a new permanent magnet geometry, the Unilateral Linear Halbach, that combines design principles from "sweet-spot" and linear Halbach magnets to achieve this goal through more efficient use of magnetic flux. We perform sensitivity analysis using numerical simulations to produce a framework for Unilateral Linear Halbach design and assess tradeoffs between design parameters. Additionally, the use of hundreds of small, discrete magnets within the assembly allows for a tunable design, improved robustness to variability in magnetization strength, and increased safety during construction. Experimental validation using a prototype magnet shows close agreement with the simulated magnetic field. The Unilateral Linear Halbach magnet increases the sensitivity, portability, and versatility of single-sided NMR. Copyright © 2018 Elsevier Inc. All rights reserved.

  2. Design and experimental validation of Unilateral Linear Halbach magnet arrays for single-sided magnetic resonance

    NASA Astrophysics Data System (ADS)

    Bashyam, Ashvin; Li, Matthew; Cima, Michael J.

    2018-07-01

    Single-sided NMR has the potential for broad utility and has found applications in healthcare, materials analysis, food quality assurance, and the oil and gas industry. These sensors require a remote, strong, uniform magnetic field to perform high sensitivity measurements. We demonstrate a new permanent magnet geometry, the Unilateral Linear Halbach, that combines design principles from "sweet-spot" and linear Halbach magnets to achieve this goal through more efficient use of magnetic flux. We perform sensitivity analysis using numerical simulations to produce a framework for Unilateral Linear Halbach design and assess tradeoffs between design parameters. Additionally, the use of hundreds of small, discrete magnets within the assembly allows for a tunable design, improved robustness to variability in magnetization strength, and increased safety during construction. Experimental validation using a prototype magnet shows close agreement with the simulated magnetic field. The Unilateral Linear Halbach magnet increases the sensitivity, portability, and versatility of single-sided NMR.

  3. Ultrawideband Electromagnetic Interference to Aircraft Radios

    NASA Technical Reports Server (NTRS)

    Ely, Jay J.; Fuller, Gerald L.; Shaver, Timothy W.

    2002-01-01

    A very recent FCC Final Rule now permits marketing and operation of new products that incorporate Ultrawideband (UWB) technology into handheld devices. Wireless product developers are working to rapidly bring this versatile, powerful and expectedly inexpensive technology into numerous consumer wireless devices. Past studies addressing the potential for passenger-carried portable electronic devices (PEDs) to interfere with aircraft electronic systems suggest that UWB transmitters may pose a significant threat to aircraft communication and navigation radio receivers. NASA, United Airlines and Eagles Wings Incorporated have performed preliminary testing that clearly shows the potential for handheld UWB transmitters to cause cockpit failure indications for the air traffic control radio beacon system (ATCRBS), blanking of aircraft on the traffic alert and collision avoidance system (TCAS) displays, and cause erratic motion and failure of instrument landing system (ILS) localizer and glideslope pointers on the pilot horizontal situation and attitude director displays. This paper provides details of the preliminary testing and recommends further assessment of aircraft systems for susceptibility to UWB electromagnetic interference.

  4. A Novel Physical Sensing Principle for Liquid Characterization Using Paper-Based Hygro-Mechanical Systems (PB-HMS).

    PubMed

    Perez-Cruz, Angel; Stiharu, Ion; Dominguez-Gonzalez, Aurelio

    2017-07-20

    In recent years paper-based microfluidic systems have emerged as versatile tools for developing sensors in different areas. In this work; we report a novel physical sensing principle for the characterization of liquids using a paper-based hygro-mechanical system (PB-HMS). The PB-HMS is formed by the interaction of liquid droplets and paper-based mini-structures such as cantilever beams. The proposed principle takes advantage of the hygroscopic properties of paper to produce hygro-mechanical motion. The dynamic response of the PB-HMS reveals information about the tested liquid that can be applied to characterize certain properties of liquids. A suggested method to characterize liquids by means of the proposed principle is introduced. The experimental results show the feasibility of such a method. It is expected that the proposed principle may be applied to sense properties of liquids in different applications where both disposability and portability are of extreme importance.

  5. The use of optical pyrometers in axial flow turbines

    NASA Astrophysics Data System (ADS)

    Sellers, R. R.; Przirembel, H. R.; Clevenger, D. H.; Lang, J. L.

    1989-07-01

    An optical pyrometer system that can be used to measure metal temperatures over an extended range of temperature has been developed. Real-time flame discrimination permits accurate operation in the gas turbine environment with high flame content. This versatile capability has been used in a number of ways. In experimental engines, a fixed angle pyrometer has been used for turbine health monitoring for the automatic test stand abort system. Turbine blade creep capability has been improved by tailoring the burner profile based on measured blade temperatures. Fixed and traversing pyrometers were used extensively during engine development to map blade surface temperatures in order to assess cooling effectiveness and identify optimum configurations. Portable units have been used in turbine field inspections. A new low temperature pyrometer is being used as a diagnostic tool in the alternate turbopump design for the Space Shuttle main engine. Advanced engine designs will incorporate pyrometers in the engine control system to limit operation to safe temperatures.

  6. A CMOS-Compatible Poly-Si Nanowire Device with Hybrid Sensor/Memory Characteristics for System-on-Chip Applications

    PubMed Central

    Chen, Min-Cheng; Chen, Hao-Yu; Lin, Chia-Yi; Chien, Chao-Hsin; Hsieh, Tsung-Fan; Horng, Jim-Tong; Qiu, Jian-Tai; Huang, Chien-Chao; Ho, Chia-Hua; Yang, Fu-Liang

    2012-01-01

    This paper reports a versatile nano-sensor technology using “top-down” poly-silicon nanowire field-effect transistors (FETs) in the conventional Complementary Metal-Oxide Semiconductor (CMOS)-compatible semiconductor process. The nanowire manufacturing technique reduced nanowire width scaling to 50 nm without use of extra lithography equipment, and exhibited superior device uniformity. These n type polysilicon nanowire FETs have positive pH sensitivity (100 mV/pH) and sensitive deoxyribonucleic acid (DNA) detection ability (100 pM) at normal system operation voltages. Specially designed oxide-nitride-oxide buried oxide nanowire realizes an electrically Vth-adjustable sensor to compensate device variation. These nanowire FETs also enable non-volatile memory application for a large and steady Vth adjustment window (>2 V Programming/Erasing window). The CMOS-compatible manufacturing technique of polysilicon nanowire FETs offers a possible solution for commercial System-on-Chip biosensor application, which enables portable physiology monitoring and in situ recording. PMID:22666012

  7. Nanoimprint of a 3D structure on an optical fiber for light wavefront manipulation.

    PubMed

    Calafiore, Giuseppe; Koshelev, Alexander; Allen, Frances I; Dhuey, Scott; Sassolini, Simone; Wong, Edward; Lum, Paul; Munechika, Keiko; Cabrini, Stefano

    2016-09-16

    Integration of complex photonic structures onto optical fiber facets enables powerful platforms with unprecedented optical functionalities. Conventional nanofabrication technologies, however, do not permit viable integration of complex photonic devices onto optical fibers owing to their low throughput and high cost. In this paper we report the fabrication of a three-dimensional structure achieved by direct nanoimprint lithography on the facet of an optical fiber. Nanoimprint processes and tools were specifically developed to enable a high lithographic accuracy and coaxial alignment of the optical device with respect to the fiber core. To demonstrate the capability of this new approach, a 3D beam splitter has been designed, imprinted and optically characterized. Scanning electron microscopy and optical measurements confirmed the good lithographic capabilities of the proposed approach as well as the desired optical performance of the imprinted structure. The inexpensive solution presented here should enable advancements in areas such as integrated optics and sensing, achieving enhanced portability and versatility of fiber optic components.

  8. Development of a portable active long-path differential optical absorption spectroscopy system for volcanic gas measurements

    USGS Publications Warehouse

    Vita, Fabio; Kern, Christoph; Inguaggiato, Salvatore

    2014-01-01

    Active long-path differential optical absorption spectroscopy (LP-DOAS) has been an effective tool for measuring atmospheric trace gases for several decades. However, instruments were large, heavy and power-inefficient, making their application to remote environments extremely challenging. Recent developments in fibre-coupling telescope technology and the availability of ultraviolet light emitting diodes (UV-LEDS) have now allowed us to design and construct a lightweight, portable, low-power LP-DOAS instrument for use at remote locations and specifically for measuring degassing from active volcanic systems. The LP-DOAS was used to measure sulfur dioxide (SO2) emissions from La Fossa crater, Vulcano, Italy, where column densities of up to 1.2 × 1018 molec cm−2 (~ 500 ppmm) were detected along open paths of up to 400 m in total length. The instrument's SO2 detection limit was determined to be 2 × 1016 molec cm−2 (~ 8 ppmm), thereby making quantitative detection of even trace amounts of SO2 possible. The instrument is capable of measuring other volcanic volatile species as well. Though the spectral evaluation of the recorded data showed that chlorine monoxide (ClO) and carbon disulfide (CS2) were both below the instrument's detection limits during the experiment, the upper limits for the X / SO2 ratio (X = ClO, CS2) could be derived, and yielded 2 × 10−3 and 0.1, respectively. The robust design and versatility of the instrument make it a promising tool for monitoring of volcanic degassing and understanding processes in a range of volcanic systems.

  9. Programmable bio-nano-chip system: a flexible point-of-care platform for bioscience and clinical measurements

    PubMed Central

    McRae, Michael. P.; Simmons, Glennon. W.; Wong, Jorge; Shadfan, Basil; Gopalkrishnan, Sanjiv; Christodoulides, Nicolaos

    2015-01-01

    The development of integrated instrumentation for universal bioassay systems serves as a key goal for the lab-on-a-chip community. The programmable bio-nano-chip (p-BNC) system is a versatile multiplexed and multiclass chemical- and bio-sensing system for bioscience and clinical measurements. The system is comprised of two main components, a disposable cartridge and a portable analyzer. The customizable single-use plastic cartridges, which now can be manufactured in high volumes using injection molding, are designed for analytical performance, ease of use, reproducibility, and low cost. These labcard devices implement high surface area nano-structured biomarker capture elements that enable high performance signaling and are index matched to real-world biological specimens. This detection modality, along with the convenience of on-chip fluid storage in blisters and self-contained waste, represents a standard process to digitize biological signatures at the point-of-care. A companion portable analyzer prototype has been developed to integrate fluid motivation, optical detection, and automated data analysis, and it serves as the human interface for complete assay automation. In this report, we provide a systems-level perspective of the p-BNC universal biosensing platform with an emphasis on flow control, device integration, and automation. To demonstrate the flexibility of the p-BNC, we distinguish diseased and non-case patients across three significant disease applications: prostate cancer, ovarian cancer, and acute myocardial infarction. Progress towards developing a rapid 7 minute myoglobin assay is presented using the fully automated p-BNC system. PMID:26308851

  10. On Ex Situ NMR: Developing portable low-cost and/or single sided NMR/MRI

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Demas, V; Herberg, J; Maxwell, R

    2006-06-09

    Nuclear magnetic resonance spectroscopy (NMR) is of unsurpassed versatility in its ability to non-destructively probe for chemical identity. Portable, low-cost NMR sensors would enable on site identification of potentially hazardous substances, such as signatures from production of nuclear, chemical, and biological weapon agents, narcotics, explosives, toxins, and poisons. There exist however problems that need to be considered in the case of such sensors: (a) small-scale magnets produce inhomogeneous magnetic fields and therefore undesired Larmor frequency distributions that conceal much of the useful spectral information, and (b) sensitivity in most experiments decreases due to the inherently low and strongly inhomogeneous fieldsmore » associated with portable instruments. Our approach is to: (a) try to improve the field of low cost magnets either with hardware (e.g. magnet design and construction of ''shim coils'') or via special pulse sequences, where the field is ''effectively shimmed'' to appear homogeneous to the sample, and (b) to use microcoils to improve sensitivity and to allow focusing in smaller regions and therefore smaller static field variations. We have been working in setting up a table top, 2-Tesla permanent Halbach magnet system for tabletop NMR. The Spectrometer console is a Tecmag Apollo, controlled by a dell notebook. Currently an external linear chemagnetics rf amplifier is being used, though the power requirements for our system are quite low (a few Watts). The Magnetic Resonance lab in LLNL, has developed several types and sizes of microcoils, which have been proven to perform well for NMR experiments. We have evaluated an rf, 360 {micro}m O.D., microcoil probe that was built previously. We have finished mapping the magnetic field of the magnet. In the optimal position (in terms of field quality), the field inhomogeneity was at 17ppm. Preliminary fluorine spectra with a resolved two peak separation have now been obtained. For the field, as mapped, we have initial designs of first degree shimming, or gradient coils (linear correction to the field). We have calculated ''shim pulses'' to effectively shim the mapped field, for ideal gradient coils. These calculations will be repeated after the coils will be built and evaluated.« less

  11. Miniature wireless recording and stimulation system for rodent behavioural testing

    NASA Astrophysics Data System (ADS)

    Pinnell, R. C.; Dempster, J.; Pratt, J.

    2015-12-01

    Objective. Elucidation of neural activity underpinning rodent behaviour has traditionally been hampered by the use of tethered systems and human involvement. Furthermore the combination of deep-brain stimulation (DBS) and various neural recording modalities can lead to complex and time-consuming laboratory setups. For studies of this type, novel tools are required to drive forward this research. Approach. A miniature wireless system weighing 8.5 g (including battery) was developed for rodent use that combined multichannel DBS and local-field potential (LFP) recordings. Its performance was verified in a working memory task that involved 4-channel fronto-hippocampal LFP recording and bilateral constant-current fimbria-fornix DBS. The system was synchronised with video-tracking for extraction of LFP at discrete task phases, and DBS was activated intermittently at discrete phases of the task. Main results. In addition to having a fast set-up time, the system could reliably transmit continuous LFP at over 8 hours across 3-5 m distances. During the working memory task, LFP pertaining to discrete task phases was extracted and compared with well-known neural correlates of active exploratory behaviour in rodents. DBS could be wirelessly activated/deactivated at any part of the experiment during EEG recording and transmission, allowing for a seamless integration of this modality. Significance. The wireless system combines a small size with a level of robustness and versatility that can greatly simplify rodent behavioural experiments involving EEG recording and DBS. Designed for versatility and simplicity, the small size and low-cost of the system and its receiver allow for enhanced portability, fast experimental setup times, and pave the way for integration with more complex behaviour.

  12. Adaptive Phase Delay Generator

    NASA Technical Reports Server (NTRS)

    Greer, Lawrence

    2013-01-01

    There are several experimental setups involving rotating machinery that require some form of synchronization. The adaptive phase delay generator (APDG) the Bencic-1000 is a flexible instrument that allows the user to generate pulses synchronized to the rising edge of a tachometer signal from any piece of rotating machinery. These synchronized pulses can vary by the delay angle, pulse width, number of pulses per period, number of skipped pulses, and total number of pulses. Due to the design of the pulse generator, any and all of these parameters can be changed independently, yielding an unparalleled level of versatility. There are two user interfaces to the APDG. The first is a LabVIEW program that has the advantage of displaying all of the pulse parameters and input signal data within one neatly organized window on the PC monitor. Furthermore, the LabVIEW interface plots the rpm of the two input signal channels in real time. The second user interface is a handheld portable device that goes anywhere a computer is not accessible. It consists of a liquid-crystal display and keypad, which enable the user to control the unit by scrolling through a host of command menus and parameter listings. The APDG combines all of the desired synchronization control into one unit. The experimenter can adjust the delay, pulse width, pulse count, number of skipped pulses, and produce a specified number of pulses per revolution. Each of these parameters can be changed independently, providing an unparalleled level of versatility when synchronizing hardware to a host of rotating machinery. The APDG allows experimenters to set up quickly and generate a host of synchronizing configurations using a simple user interface, which hopefully leads to faster results.

  13. Nanocomposites with embedded structures for lithium-ion batteries

    NASA Astrophysics Data System (ADS)

    Yang, Zichao

    Lithium-ion batteries (LIBs) have been widely employed in portable electronics and are rapidly expanding into emerging markets such as hybrid and electric vehicles and potentially electric grid storage. These new opportunities create new challenges for LIBs and further improvement of specific energy, cycling performance and rate capability are required. A major strategy in performance enhancement for the electrode materials involves the creation of carbon composites to provide mechanical buffering of active material and to improve electrical conductivity. In the current work, a platform is developed for creating functional hybrid materials by copolymerization of organic molecules and inorganic compounds followed by thermal pyrolysis, and the approach yields nanostructured composites in which nanoparticles are uniformly embedded in a porous, partially graphitic carbon matrix. Depending upon the chemistry of the starting materials, nanocomposites with embedded structures created using the approach are attractive as anode or cathode materials for next-generation rechargeable lithium battery systems. The platform is very versatile and through ex situ conversion or utilization of multiple precursors, can be applied to various classes of materials including metal oxides (single or mixed), metals, metal sulfides, alloys, metalloids, phosphates, etc. The approach also lends itself to the development of scalable processes for production of nanostructured battery materials. Mechanistic analysis was performed and reveals that the performance enhancement of the embedded nanocomposite configuration is mainly brought about by the mechanical buffering effect offered by the carbon matrix. The active material loading was shown to be an important factor in the design of the composites as electrode materials. In addition to the polymerization-based approach, other in situ methods such as one based on spray pyrolysis are also explored and demonstrate the versatility of the in situ synthesis concept.

  14. Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics.

    PubMed

    Knowlton, Stephanie M; Yenilmez, Bekir; Amin, Reza; Tasoglu, Savas

    2017-02-19

    Currently, many clinical diagnostic procedures are complex, costly, inefficient, and inaccessible to a large population in the world. The requirements for specialized equipment and trained personnel require that many diagnostic tests be performed at remote, centralized clinical laboratories. Magnetic levitation is a simple yet powerful technique and can be applied to levitate cells, which are suspended in a paramagnetic solution and placed in a magnetic field, at a position determined by equilibrium between a magnetic force and a buoyancy force. Here, we present a versatile platform technology designed for point-of-care diagnostics which uses magnetic levitation coupled to microscopic imaging and automated analysis to determine the density distribution of a patient's cells as a useful diagnostic indicator. We present two platforms operating on this principle: (i) a smartphone-compatible version of the technology, where the built-in smartphone camera is used to image cells in the magnetic field and a smartphone application processes the images and to measures the density distribution of the cells and (ii) a self-contained version where a camera board is used to capture images and an embedded processing unit with attached thin-film-transistor (TFT) screen measures and displays the results. Demonstrated applications include: (i) measuring the altered distribution of a cell population with a disease phenotype compared to a healthy phenotype, which is applied to sickle cell disease diagnosis, and (ii) separation of different cell types based on their characteristic densities, which is applied to separate white blood cells from red blood cells for white blood cell cytometry. These applications, as well as future extensions of the essential density-based measurements enabled by this portable, user-friendly platform technology, will significantly enhance disease diagnostic capabilities at the point of care.

  15. Omnidirectional spin-wave nanograting coupler

    PubMed Central

    Yu, Haiming; Duerr, G.; Huber, R.; Bahr, M.; Schwarze, T.; Brandl, F.; Grundler, D.

    2013-01-01

    Magnonics as an emerging nanotechnology offers functionalities beyond current semiconductor technology. Spin waves used in cellular nonlinear networks are expected to speed up technologically, demanding tasks such as image processing and speech recognition at low power consumption. However, efficient coupling to microelectronics poses a vital challenge. Previously developed techniques for spin-wave excitation (for example, by using parametric pumping in a cavity) may not allow for the relevant downscaling or provide only individual point-like sources. Here we demonstrate that a grating coupler of periodically nanostructured magnets provokes multidirectional emission of short-wavelength spin waves with giantly enhanced amplitude compared with a bare microwave antenna. Exploring the dependence on ferromagnetic materials, lattice constants and the applied magnetic field, we find the magnonic grating coupler to be more versatile compared with gratings in photonics and plasmonics. Our results allow one to convert, in particular, straight microwave antennas into omnidirectional emitters for short-wavelength spin waves, which are key to cellular nonlinear networks and integrated magnonics. PMID:24189978

  16. Portable Intermodal Preferential Looking (IPL): investigating language comprehension in typically developing toddlers and young children with autism.

    PubMed

    Naigles, Letitia R; Tovar, Andrea T

    2012-12-14

    One of the defining characteristics of autism spectrum disorder (ASD) is difficulty with language and communication.(1) Children with ASD's onset of speaking is usually delayed, and many children with ASD consistently produce language less frequently and of lower lexical and grammatical complexity than their typically developing (TD) peers.(6,8,12,23) However, children with ASD also exhibit a significant social deficit, and researchers and clinicians continue to debate the extent to which the deficits in social interaction account for or contribute to the deficits in language production.(5,14,19,25) Standardized assessments of language in children with ASD usually do include a comprehension component; however, many such comprehension tasks assess just one aspect of language (e.g., vocabulary),(5) or include a significant motor component (e.g., pointing, act-out), and/or require children to deliberately choose between a number of alternatives. These last two behaviors are known to also be challenging to children with ASD.(7,12,13,16) We present a method which can assess the language comprehension of young typically developing children (9-36 months) and children with autism.(2,4,9,11,22) This method, Portable Intermodal Preferential Looking (P-IPL), projects side-by-side video images from a laptop onto a portable screen. The video images are paired first with a 'baseline' (nondirecting) audio, and then presented again paired with a 'test' linguistic audio that matches only one of the video images. Children's eye movements while watching the video are filmed and later coded. Children who understand the linguistic audio will look more quickly to, and longer at, the video that matches the linguistic audio.(2,4,11,18,22,26) This paradigm includes a number of components that have recently been miniaturized (projector, camcorder, digitizer) to enable portability and easy setup in children's homes. This is a crucial point for assessing young children with ASD, who are frequently uncomfortable in new (e.g., laboratory) settings. Videos can be created to assess a wide range of specific components of linguistic knowledge, such as Subject-Verb-Object word order, wh-questions, and tense/aspect suffixes on verbs; videos can also assess principles of word learning such as a noun bias, a shape bias, and syntactic bootstrapping.(10,14,17,21,24) Videos include characters and speech that are visually and acoustically salient and well tolerated by children with ASD.

  17. A survey of Australian adult users of altered auditory feedback devices for stuttering: use patterns, perceived effectiveness and satisfaction.

    PubMed

    Lincoln, Michelle; Walker, Clare

    2007-10-15

    Small portable devices that provide delayed auditory feedback (DAF) and/or frequency altered feedback (FAF) have been developed and marketed to clinicians and people who stutter as fluency enhancing aids for use in everyday speaking situations. The literature contains many laboratory-based reports about the impact of altered auditory feedback (AAF) on the speech of people who stutter but few reports about its use in everyday speaking situations. This paper investigates use patterns and perceptions of the effectiveness and satisfaction with AAF devices. The current study surveys 14 Australian AAF users. The survey responses revealed varied opinions about AAF devices and their use and effectiveness in everyday speaking situations. Opinions were somewhat related to the type of device used. The results of this study provide some important directions for future research. In particular there is need to investigate the effectiveness of AAF devices when used in conjunction with other traditional treatments.

  18. Semi Automatic Ontology Instantiation in the domain of Risk Management

    NASA Astrophysics Data System (ADS)

    Makki, Jawad; Alquier, Anne-Marie; Prince, Violaine

    One of the challenging tasks in the context of Ontological Engineering is to automatically or semi-automatically support the process of Ontology Learning and Ontology Population from semi-structured documents (texts). In this paper we describe a Semi-Automatic Ontology Instantiation method from natural language text, in the domain of Risk Management. This method is composed from three steps 1 ) Annotation with part-of-speech tags, 2) Semantic Relation Instances Extraction, 3) Ontology instantiation process. It's based on combined NLP techniques using human intervention between steps 2 and 3 for control and validation. Since it heavily relies on linguistic knowledge it is not domain dependent which is a good feature for portability between the different fields of risk management application. The proposed methodology uses the ontology of the PRIMA1 project (supported by the European community) as a Generic Domain Ontology and populates it via an available corpus. A first validation of the approach is done through an experiment with Chemical Fact Sheets from Environmental Protection Agency2.

  19. Advanced materials for energy storage.

    PubMed

    Liu, Chang; Li, Feng; Ma, Lai-Peng; Cheng, Hui-Ming

    2010-02-23

    Popularization of portable electronics and electric vehicles worldwide stimulates the development of energy storage devices, such as batteries and supercapacitors, toward higher power density and energy density, which significantly depends upon the advancement of new materials used in these devices. Moreover, energy storage materials play a key role in efficient, clean, and versatile use of energy, and are crucial for the exploitation of renewable energy. Therefore, energy storage materials cover a wide range of materials and have been receiving intensive attention from research and development to industrialization. In this Review, firstly a general introduction is given to several typical energy storage systems, including thermal, mechanical, electromagnetic, hydrogen, and electrochemical energy storage. Then the current status of high-performance hydrogen storage materials for on-board applications and electrochemical energy storage materials for lithium-ion batteries and supercapacitors is introduced in detail. The strategies for developing these advanced energy storage materials, including nanostructuring, nano-/microcombination, hybridization, pore-structure control, configuration design, surface modification, and composition optimization, are discussed. Finally, the future trends and prospects in the development of advanced energy storage materials are highlighted.

  20. Multiheterodyne spectroscopy using interband cascade lasers

    NASA Astrophysics Data System (ADS)

    Sterczewski, Lukasz A.; Westberg, Jonas; Patrick, Charles Link; Kim, Chul Soo; Kim, Mijin; Canedy, Chadwick L.; Bewley, William W.; Merritt, Charles D.; Vurgaftman, Igor; Meyer, Jerry R.; Wysocki, Gerard

    2018-01-01

    While midinfrared radiation can be used to identify and quantify numerous chemical species, contemporary broadband midinfrared spectroscopic systems are often hindered by large footprints, moving parts, and high power consumption. In this work, we demonstrate multiheterodyne spectroscopy (MHS) using interband cascade lasers, which combines broadband spectral coverage with high spectral resolution and energy-efficient operation. The lasers generate up to 30 mW of continuous-wave optical power while consuming <0.5 W of electrical power. A computational phase and timing correction algorithm is used to obtain kHz linewidths of the multiheterodyne beat notes and up to 30 dB improvement in signal-to-noise ratio. The versatility of the multiheterodyne technique is demonstrated by performing both rapidly swept absorption and dispersion spectroscopic assessments of low-pressure ethylene (C2H4) acquired by extracting a single beat note from the multiheterodyne signal, as well as broadband MHS of methane (CH4) acquired with all available beat notes with microsecond temporal resolution and an instantaneous optical bandwidth of ˜240 GHz. The technology shows excellent potential for portable and high-resolution solid-state spectroscopic chemical sensors operating in the midinfrared.

  1. Fabrication and gas sensing properties of vertically aligned Si nanowires

    NASA Astrophysics Data System (ADS)

    Mirzaei, Ali; Kang, Sung Yong; Choi, Sun-Woo; Kwon, Yong Jung; Choi, Myung Sik; Bang, Jae Hoon; Kim, Sang Sub; Kim, Hyoun Woo

    2018-01-01

    In this study, a peculiar configuration for a gas sensor consisting of vertically aligned silicon nanowires (VA-Si NWs) synthesized by metal-assisted chemical etching (MACE) is reported. Si NWs were prepared via a facile MACE method and subsequent thermal annealing. Etching was performed by generation of silver nanoparticles (Ag NPs) and subsequent etching in HF/H2O2 aqueous solution; the growth conditions were optimized by changing the process parameters. Highly vertically oriented arrays of Si NWs with a straight-line morphology were obtained, and a top-top electrode configuration was applied. The VA-Si NW gas sensor showed good sensing performance, and the VA-Si NWs exhibited a remarkable response (Rg/Ra = 11.5 ∼ 17.1) to H2 gas (10-50 ppm) at 100 °C which was the optimal working temperature. The formation mechanism and gas sensing mechanism of VA-Si NWs are described. The obtained results can suggest new approaches to making inexpensive, versatile, and portable sensors based on Si NWs having a novel top-top electrode structure that are fully compatible with well-developed Si technologies.

  2. One hundred fold increase in current carrying capacity in a carbon nanotube–copper composite

    PubMed Central

    Subramaniam, Chandramouli; Yamada, Takeo; Kobashi, Kazufumi; Sekiguchi, Atsuko; Futaba, Don N.; Yumura, Motoo; Hata, Kenji

    2013-01-01

    Increased portability, versatility and ubiquity of electronics devices are a result of their progressive miniaturization, requiring current flow through narrow channels. Present-day devices operate close to the maximum current-carrying-capacity (that is, ampacity) of conductors (such as copper and gold), leading to decreased lifetime and performance, creating demand for new conductors with higher ampacity. Ampacity represents the maximum current-carrying capacity of the object that depends both on the structure and material. Here we report a carbon nanotube–copper composite exhibiting similar conductivity (2.3–4.7 × 105 S cm−1) as copper (5.8 × 105 S cm−1), but with a 100-times higher ampacity (6 × 108 A cm−2). Vacuum experiments demonstrate that carbon nanotubes suppress the primary failure pathways in copper as observed by the increased copper diffusion activation energy (∼2.0 eV) in carbon nanotube–copper composite, explaining its higher ampacity. This is the only material with both high conductivity and high ampacity, making it uniquely suited for applications in microscale electronics and inverters. PMID:23877359

  3. Photography in Dermatologic Surgery: Selection of an Appropriate Lighting Solution for a Particular Clinical Application.

    PubMed

    Chen, Brian R; Poon, Emily; Alam, Murad

    2018-01-01

    Lighting is an important component of consistent, high-quality dermatologic photography. There are different types of lighting solutions available. To evaluate currently available lighting equipment and methods suitable for procedural dermatology. Overhead lighting, built-in camera flashes, external flash units, studio strobes, and light-emitting diode (LED) light panels were evaluated with regard to their utility for dermatologic surgeons. A set of ideal lighting characteristics was used to examine the capabilities and limitations of each type of lighting solution. Recommendations regarding lighting solutions and optimal usage configurations were made in terms of the context of the clinical environment and the purpose of the image. Overhead lighting may be a convenient option for general documentation. An on-camera lighting solution using a built-in camera flash or a camera-mounted external flash unit provides portability and consistent lighting with minimal training. An off-camera lighting solution with studio strobes, external flash units, or LED light panels provides versatility and even lighting with minimal shadows and glare. The selection of an optimal lighting solution is contingent on practical considerations and the purpose of the image.

  4. Education: DNA replication using microscale natural convection.

    PubMed

    Priye, Aashish; Hassan, Yassin A; Ugaz, Victor M

    2012-12-07

    There is a need for innovative educational experiences that unify and reinforce fundamental principles at the interface between the physical, chemical, and life sciences. These experiences empower and excite students by helping them recognize how interdisciplinary knowledge can be applied to develop new products and technologies that benefit society. Microfluidics offers an incredibly versatile tool to address this need. Here we describe our efforts to create innovative hands-on activities that introduce chemical engineering students to molecular biology by challenging them to harness microscale natural convection phenomena to perform DNA replication via the polymerase chain reaction (PCR). Experimentally, we have constructed convective PCR stations incorporating a simple design for loading and mounting cylindrical microfluidic reactors between independently controlled thermal plates. A portable motion analysis microscope enables flow patterns inside the convective reactors to be directly visualized using fluorescent bead tracers. We have also developed a hands-on computational fluid dynamics (CFD) exercise based on modeling microscale thermal convection to identify optimal geometries for DNA replication. A cognitive assessment reveals that these activities strongly impact student learning in a positive way.

  5. Measurement of vortex flow fields

    NASA Technical Reports Server (NTRS)

    Mcdevitt, T. Kevin; Ambur, Todd A.; Orngard, Gary M.; Owen, F. Kevin

    1992-01-01

    A 3-D laser fluorescence anemometer (LFA) was designed, built, and demonstrated for use in the Langley 16 x 24 inch Water Tunnel. Innovative optical design flexibility combined with compact and portable data acquisition and control systems were incorporated into the instrument. This will allow its use by NASA in other test facilities. A versatile fiber optic system facilities normal and off-axis laser beam alignment, removes mirror losses and improves laser safety. This added optical flexibility will also enable simple adaptation for use in the adjacent jet facility. New proprietary concepts in transmitting color separation, light collection, and novel prism separation of the scattered light was also designed and built into the system. Off-axis beam traverse and alignment complexity led to the requirement for a specialized, programmable transverse controller, and the inclusion of an additional traverse for the off-axis arm. To meet this challenge, an 'in-house' prototype unit was designed and built and traverse control software developed specifically for the water tunnel traverse applications. A specialized data acquisition interface was also required. This was designed and built for the LFA system.

  6. DNA origami-based standards for quantitative fluorescence microscopy.

    PubMed

    Schmied, Jürgen J; Raab, Mario; Forthmann, Carsten; Pibiri, Enrico; Wünsch, Bettina; Dammeyer, Thorben; Tinnefeld, Philip

    2014-01-01

    Validating and testing a fluorescence microscope or a microscopy method requires defined samples that can be used as standards. DNA origami is a new tool that provides a framework to place defined numbers of small molecules such as fluorescent dyes or proteins in a programmed geometry with nanometer precision. The flexibility and versatility in the design of DNA origami microscopy standards makes them ideally suited for the broad variety of emerging super-resolution microscopy methods. As DNA origami structures are durable and portable, they can become a universally available specimen to check the everyday functionality of a microscope. The standards are immobilized on a glass slide, and they can be imaged without further preparation and can be stored for up to 6 months. We describe a detailed protocol for the design, production and use of DNA origami microscopy standards, and we introduce a DNA origami rectangle, bundles and a nanopillar as fluorescent nanoscopic rulers. The protocol provides procedures for the design and realization of fluorescent marks on DNA origami structures, their production and purification, quality control, handling, immobilization, measurement and data analysis. The procedure can be completed in 1-2 d.

  7. One hundred fold increase in current carrying capacity in a carbon nanotube-copper composite

    NASA Astrophysics Data System (ADS)

    Subramaniam, Chandramouli; Yamada, Takeo; Kobashi, Kazufumi; Sekiguchi, Atsuko; Futaba, Don N.; Yumura, Motoo; Hata, Kenji

    2013-07-01

    Increased portability, versatility and ubiquity of electronics devices are a result of their progressive miniaturization, requiring current flow through narrow channels. Present-day devices operate close to the maximum current-carrying-capacity (that is, ampacity) of conductors (such as copper and gold), leading to decreased lifetime and performance, creating demand for new conductors with higher ampacity. Ampacity represents the maximum current-carrying capacity of the object that depends both on the structure and material. Here we report a carbon nanotube-copper composite exhibiting similar conductivity (2.3-4.7 × 105Scm-1) as copper (5.8 × 105Scm-1), but with a 100-times higher ampacity (6 × 108Acm-2). Vacuum experiments demonstrate that carbon nanotubes suppress the primary failure pathways in copper as observed by the increased copper diffusion activation energy (~2.0eV) in carbon nanotube-copper composite, explaining its higher ampacity. This is the only material with both high conductivity and high ampacity, making it uniquely suited for applications in microscale electronics and inverters.

  8. Printable Fabrication of Nanocoral-Structured Electrodes for High-Performance Flexible and Planar Supercapacitor with Artistic Design.

    PubMed

    Lin, Yuanjing; Gao, Yuan; Fan, Zhiyong

    2017-11-01

    Planar supercapacitors with high flexibility, desirable operation safety, and high performance are considered as attractive candidates to serve as energy-storage devices for portable and wearable electronics. Here, a scalable and printable technique is adopted to construct novel and unique hierarchical nanocoral structures as the interdigitated electrodes on flexible substrates. The as-fabricated flexible all-solid-state planar supercapacitors with nanocoral structures achieve areal capacitance up to 52.9 mF cm -2 , which is 2.5 times that of devices without nanocoral structures, and this figure-of-merit is among the highest in the literature for the same category of devices. More interestingly, due to utilization of the inkjet-printing technique, excellent versatility on electrode-pattern artistic design is achieved. Particularly, working supercapacitors with artistically designed patterns are demonstrated. Meanwhile, the high scalability of such a printable method is also demonstrated by fabrication of large-sized artistic supercapacitors serving as energy-storage devices in a wearable self-powered system as a proof of concept. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. TMAP - A Versatile Mobile Robot

    NASA Astrophysics Data System (ADS)

    Weiss, Joel A.; Simmons, Richard K.

    1989-03-01

    TMAP, the Teleoperated Mobile All-purpose Platform, provides the Army with a low cost, light weight, flexibly designed, modularly expandable platform for support of maneuver forces and light infantry units. The highly mobile, four wheel drive, diesel-hydraulic platform is controllable at distances of up to 4km from a portable operator control unit using either fiber optic or RF control links. The Martin Marietta TMAP system is based on a hierarchical task decomposition Real-time Control System architecture that readily supports interchange of mission packages and provides the capability for simple incorporation of supervisory control concepts leading to increased system autonomy and resulting force multiplication. TMAP has been designed to support a variety of missions including target designation, anti-armor, anti-air, countermine, and reconnaissance/surveillance. As a target designation system TMAP will provide the soldier with increased survivability and effectiveness by providing substantial combat standoff, and the firepower effectiveness of several manual designator operators. Force-on-force analysis of simulated TMAP engagements indicate that TMAP should provide significant force multiplication for the Army in Air-Land Battle 2000.

  10. A generic framework for individual-based modelling and physical-biological interaction

    PubMed Central

    2018-01-01

    The increased availability of high-resolution ocean data globally has enabled more detailed analyses of physical-biological interactions and their consequences to the ecosystem. We present IBMlib, which is a versatile, portable and computationally effective framework for conducting Lagrangian simulations in the marine environment. The purpose of the framework is to handle complex individual-level biological models of organisms, combined with realistic 3D oceanographic model of physics and biogeochemistry describing the environment of the organisms without assumptions about spatial or temporal scales. The open-source framework features a minimal robust interface to facilitate the coupling between individual-level biological models and oceanographic models, and we provide application examples including forward/backward simulations, habitat connectivity calculations, assessing ocean conditions, comparison of physical circulation models, model ensemble runs and recently posterior Eulerian simulations using the IBMlib framework. We present the code design ideas behind the longevity of the code, our implementation experiences, as well as code performance benchmarking. The framework may contribute substantially to progresses in representing, understanding, predicting and eventually managing marine ecosystems. PMID:29351280

  11. An innovative multimodal virtual platform for communication with devices in a natural way

    NASA Astrophysics Data System (ADS)

    Kinkar, Chhayarani R.; Golash, Richa; Upadhyay, Akhilesh R.

    2012-03-01

    As technology grows people are diverted and are more interested in communicating with machine or computer naturally. This will make machine more compact and portable by avoiding remote, keyboard etc. also it will help them to live in an environment free from electromagnetic waves. This thought has made 'recognition of natural modality in human computer interaction' a most appealing and promising research field. Simultaneously it has been observed that using single mode of interaction limit the complete utilization of commands as well as data flow. In this paper a multimodal platform, where out of many natural modalities like eye gaze, speech, voice, face etc. human gestures are combined with human voice is proposed which will minimize the mean square error. This will loosen the strict environment needed for accurate and robust interaction while using single mode. Gesture complement Speech, gestures are ideal for direct object manipulation and natural language is used for descriptive tasks. Human computer interaction basically requires two broad sections recognition and interpretation. Recognition and interpretation of natural modality in complex binary instruction is a tough task as it integrate real world to virtual environment. The main idea of the paper is to develop a efficient model for data fusion coming from heterogeneous sensors, camera and microphone. Through this paper we have analyzed that the efficiency is increased if heterogeneous data (image & voice) is combined at feature level using artificial intelligence. The long term goal of this paper is to design a robust system for physically not able or having less technical knowledge.

  12. 46 CFR 119.458 - Portable fuel systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Portable fuel systems. 119.458 Section 119.458 Shipping... Machinery Requirements § 119.458 Portable fuel systems. (a) Portable fuel systems, including portable tanks and related fuel lines and accessories, are prohibited except where used for portable dewatering pumps...

  13. 46 CFR 119.458 - Portable fuel systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Portable fuel systems. 119.458 Section 119.458 Shipping... Machinery Requirements § 119.458 Portable fuel systems. (a) Portable fuel systems, including portable tanks and related fuel lines and accessories, are prohibited except where used for portable dewatering pumps...

  14. 30 CFR 75.1100-2 - Quantity and location of firefighting equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...-trip car, or personnel carrier shall be equipped with one portable fire extinguisher. (e) Electrical... loading point is provided with one of the following: (i) Two portable water cars; or (ii) Two portable chemical cars; or (iii) One portable water car or one portable chemical car, and either (a) a portable foam...

  15. 30 CFR 75.1100-2 - Quantity and location of firefighting equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...-trip car, or personnel carrier shall be equipped with one portable fire extinguisher. (e) Electrical... loading point is provided with one of the following: (i) Two portable water cars; or (ii) Two portable chemical cars; or (iii) One portable water car or one portable chemical car, and either (a) a portable foam...

  16. 30 CFR 75.1100-2 - Quantity and location of firefighting equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...-trip car, or personnel carrier shall be equipped with one portable fire extinguisher. (e) Electrical... loading point is provided with one of the following: (i) Two portable water cars; or (ii) Two portable chemical cars; or (iii) One portable water car or one portable chemical car, and either (a) a portable foam...

  17. 30 CFR 75.1100-2 - Quantity and location of firefighting equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-trip car, or personnel carrier shall be equipped with one portable fire extinguisher. (e) Electrical... loading point is provided with one of the following: (i) Two portable water cars; or (ii) Two portable chemical cars; or (iii) One portable water car or one portable chemical car, and either (a) a portable foam...

  18. 30 CFR 75.1100-2 - Quantity and location of firefighting equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...-trip car, or personnel carrier shall be equipped with one portable fire extinguisher. (e) Electrical... loading point is provided with one of the following: (i) Two portable water cars; or (ii) Two portable chemical cars; or (iii) One portable water car or one portable chemical car, and either (a) a portable foam...

  19. Portable apparatus for separating sample and detecting target analytes

    DOEpatents

    Renzi, Ronald F.; Wally, Karl; Crocker, Robert W.; Stamps, James F.; Griffiths; Stewart K. ,; Fruetel, Julia A.; Horn, Brent A.; Shokair, Isaac R.; Yee, Daniel D.; VanderNoot, Victoria A.; Wiedenman, Boyd J.; West, Jason A. A.; Ferko, Scott M.

    2008-11-18

    Portable devices and methods for determining the presence of a target analyte using a portable device are provided. The portable device is preferably hand-held. A sample is injected to the portable device. A microfluidic separation is performed within the portable device and at least one separated component detected by a detection module within the portable device, in embodiments of the invention. A target analyte is identified, based on the separated component, and the presence of the target analyte is indicated on an output interface of the portable device, in accordance with embodiments of the invention.

  20. 46 CFR 98.30-6 - Lifting a portable tank.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Lifting a portable tank. 98.30-6 Section 98.30-6... CONSTRUCTION, ARRANGEMENT, AND OTHER PROVISIONS FOR CERTAIN DANGEROUS CARGOES IN BULK Portable Tanks § 98.30-6 Lifting a portable tank. No person may lift a portable tank with another portable tank. [CGD 73-172, 39 FR...

  1. 78 FR 49693 - Speech-to-Speech and Internet Protocol (IP) Speech-to-Speech Telecommunications Relay Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-15

    ...] Speech-to-Speech and Internet Protocol (IP) Speech-to-Speech Telecommunications Relay Services...: This is a summary of the Commission's Speech-to-Speech and Internet Protocol (IP) Speech-to-Speech...), Internet Protocol Relay (IP Relay), and IP captioned telephone service (IP CTS) as compensable forms of TRS...

  2. 49 CFR 174.63 - Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car tanks. 174.63 Section 174.63 Transportation Other....63 Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

  3. 49 CFR 174.63 - Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car tanks. 174.63 Section 174.63 Transportation Other....63 Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

  4. 49 CFR 174.63 - Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car tanks. 174.63 Section 174.63 Transportation Other....63 Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

  5. 49 CFR 174.63 - Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car tanks. 174.63 Section 174.63 Transportation Other....63 Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

  6. 49 CFR 174.63 - Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 2 2012-10-01 2012-10-01 false Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car tanks. 174.63 Section 174.63 Transportation Other....63 Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

  7. 47 CFR 52.26 - NANC Recommendations on Local Number Portability Administration.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Portability Administration. 52.26 Section 52.26 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED... Number Portability Administration. (a) Local number portability administration shall comply with the... prepared by the NANC's Local Number Portability Administration Selection Working Group, dated April 25...

  8. 47 CFR 52.26 - NANC Recommendations on Local Number Portability Administration.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Portability Administration. 52.26 Section 52.26 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED... Number Portability Administration. (a) Local number portability administration shall comply with the... prepared by the NANC's Local Number Portability Administration Selection Working Group, dated April 25...

  9. Role versatility among men who have sex with men in urban Peru.

    PubMed

    Goodreau, Steven M; Peinado, Jesus; Goicochea, Pedro; Vergara, Jorge; Ojeda, Nora; Casapia, Martin; Ortiz, Abner; Zamalloa, Victoria; Galvan, Rosa; Sanchez, Jorge R

    2007-08-01

    Role versatility refers to the practice in which individual men who have sex with men (MSM) play both insertive and receptive sexual roles over time. Versatility has been thought to be relatively uncommon among Latin American MSM but possibly rising. Versatility has also been shown to be a potentially large population-level risk factor for HIV infection. In this study we examine the correlates of versatile behavior and identity among 2,655 MSM in six Peruvian cities. Versatile behavior with recent male partners was found in 9% of men and versatile ("moderno") identity was reported by 16%. Significant predictors included high education, white-collar occupation, sex work, and residence in Lima. Age was not significant in any analysis. Since sex work is negatively correlated with other predictors, versatile men appear to comprise two distinct sub-populations. Insertive-only men appear to play a strong role in bridging the HIV epidemic between MSM and women.

  10. Real-time spectroscopic monitoring of photocatalytic activity promoted by graphene in a microfluidic reactor

    PubMed Central

    Li, Yifan; Lin, Beichen; Ge, Likai; Guo, Hongchen; Chen, Xinyi; Lu, Miao

    2016-01-01

    Photocatalytic microreactors have been utilized as rapid, versatile platforms for the characterization of photocatalysts. In this work, a photocatalytic microreactor integrated with absorption spectroscopy was proposed for the real-time monitoring of photocatalytic activity using different catalysts. The validity of this method was investigated by the rapid screening on the photocatalytic performance of a titanium oxide (TiO2)-decorated graphene oxide (GO) sheet for the degradation of methylene blue under monochromatic visible irradiation. The sampling interval time could be minimized to 10 s for achieving real-time detection. The best photocatalytic activity was observed for an optimized TiO2/GO weight mixing ratio of 7:11, with a reaction rate constant up to 0.067 min−1. The addition of GO into TiO2 enhances photocatalytic activity and adsorption of MB molecules. The synthetic reaction rate constant was up to approximately 0.11 min−1, which was also the highest among the catalysts. The microreactor exhibited good sensitivity and reproducibility without weakening the performance of the photocatalysts. Consequently, the photocatalytic microreactor is promising as a simple, portable, and rapid screening tool for new photocatalysts. PMID:27346555

  11. Real-time spectroscopic monitoring of photocatalytic activity promoted by graphene in a microfluidic reactor

    NASA Astrophysics Data System (ADS)

    Li, Yifan; Lin, Beichen; Ge, Likai; Guo, Hongchen; Chen, Xinyi; Lu, Miao

    2016-06-01

    Photocatalytic microreactors have been utilized as rapid, versatile platforms for the characterization of photocatalysts. In this work, a photocatalytic microreactor integrated with absorption spectroscopy was proposed for the real-time monitoring of photocatalytic activity using different catalysts. The validity of this method was investigated by the rapid screening on the photocatalytic performance of a titanium oxide (TiO2)-decorated graphene oxide (GO) sheet for the degradation of methylene blue under monochromatic visible irradiation. The sampling interval time could be minimized to 10 s for achieving real-time detection. The best photocatalytic activity was observed for an optimized TiO2/GO weight mixing ratio of 7:11, with a reaction rate constant up to 0.067 min-1. The addition of GO into TiO2 enhances photocatalytic activity and adsorption of MB molecules. The synthetic reaction rate constant was up to approximately 0.11 min-1, which was also the highest among the catalysts. The microreactor exhibited good sensitivity and reproducibility without weakening the performance of the photocatalysts. Consequently, the photocatalytic microreactor is promising as a simple, portable, and rapid screening tool for new photocatalysts.

  12. Hybrid nanogenerators for low frequency vibration energy harvesting and self-powered wireless locating

    NASA Astrophysics Data System (ADS)

    Yuan, Ying; Zhang, Hulin; Wang, Jie; Xie, Yuhang; Khan, Saeed Ahmed; Jin, Long; Yan, Zhuocheng; Huang, Long; Pan, Taisong; Yang, Weiqing; Lin, Yuan

    2018-01-01

    Hybrid energy harvesters based on different physical effects is fascinating, but a rational design for multiple energy harvesting is challenging. In this work, a spring-magnet oscillator-based triboelectric-electromagnetic generator (EMG) with a solar cell cap is proposed. A power was produced by a triboelectric nanogenerator (TENG) and an EMG independently or simultaneously by using a shared spring-magnet oscillator. The oscillator configuration enables versatile energy harvesting with the excellent size scalability and self-packaged structure which can perform well at low frequency ranging from 3.5 to 5 Hz. The solar cell cap mounted above the oscillator can harvest solar energy. Under vibrations at the frequency of 4 Hz, the TENG and the EMG produced maximum output power of 5.46 nW cm-3 and 378.79 μW cm-3, respectively. The generated electricity by the hybrid nanogenerator can be stored in a capacitor or Li-ion battery, which is capable of powering a wireless locator for real-time locating data reporting to a personal cell phone. The light-weight and handy hybrid nanogenerator can directly light a caution light or play as a portable flashlight by shaking hands at night.

  13. Miniaturized Monitors for Assessment of Exposure to Air Pollutants: A Review.

    PubMed

    Borghi, Francesca; Spinazzè, Andrea; Rovelli, Sabrina; Campagnolo, Davide; Del Buono, Luca; Cattaneo, Andrea; Cavallo, Domenico M

    2017-08-12

    Air quality has a huge impact on different aspects of life quality, and for this reason, air quality monitoring is required by national and international regulations. Technical and procedural limitations of traditional fixed-site stations for monitoring or sampling of air pollutants are also well-known. Recently, a different type of miniaturized monitors has been developed. These monitors, due to their characteristics (e.g., low cost, small size, high portability) are becoming increasingly important for individual exposure assessment, especially since this kind of instrument can provide measurements at high spatial and temporal resolution, which is a notable advantage when approaching assessment of exposure to environmental contaminants. The aim of this study is indeed to provide information regarding current knowledge regarding the use of miniaturized air pollutant sensors. A systematic review was performed to identify original articles: a literature search was carried out using an appropriate query for the search of papers across three different databases, and the papers were selected using inclusion/exclusion criteria. The reviewed articles showed that miniaturized sensors are particularly versatile and could be applied in studies with different experimental designs, helping to provide a significant enhancement to exposure assessment, even though studies regarding their performance are still sparse.

  14. Microfluidics Integrated Biosensors: A Leading Technology towards Lab-on-a-Chip and Sensing Applications

    PubMed Central

    Luka, George; Ahmadi, Ali; Najjaran, Homayoun; Alocilja, Evangelyn; DeRosa, Maria; Wolthers, Kirsten; Malki, Ahmed; Aziz, Hassan; Althani, Asmaa; Hoorfar, Mina

    2015-01-01

    A biosensor can be defined as a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element immobilized on a physicochemical transducer to measure one or more analytes. Microfluidic systems, on the other hand, provide throughput processing, enhance transport for controlling the flow conditions, increase the mixing rate of different reagents, reduce sample and reagents volume (down to nanoliter), increase sensitivity of detection, and utilize the same platform for both sample preparation and detection. In view of these advantages, the integration of microfluidic and biosensor technologies provides the ability to merge chemical and biological components into a single platform and offers new opportunities for future biosensing applications including portability, disposability, real-time detection, unprecedented accuracies, and simultaneous analysis of different analytes in a single device. This review aims at representing advances and achievements in the field of microfluidic-based biosensing. The review also presents examples extracted from the literature to demonstrate the advantages of merging microfluidic and biosensing technologies and illustrate the versatility that such integration promises in the future biosensing for emerging areas of biological engineering, biomedical studies, point-of-care diagnostics, environmental monitoring, and precision agriculture. PMID:26633409

  15. Flexible and Compressible PEDOT:PSS@Melamine Conductive Sponge Prepared via One-Step Dip Coating as Piezoresistive Pressure Sensor for Human Motion Detection.

    PubMed

    Ding, Yichun; Yang, Jack; Tolle, Charles R; Zhu, Zhengtao

    2018-05-09

    Flexible and wearable pressure sensor may offer convenient, timely, and portable solutions to human motion detection, yet it is a challenge to develop cost-effective materials for pressure sensor with high compressibility and sensitivity. Herein, a cost-efficient and scalable approach is reported to prepare a highly flexible and compressible conductive sponge for piezoresistive pressure sensor. The conductive sponge, poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS)@melamine sponge (MS), is prepared by one-step dip coating the commercial melamine sponge (MS) in an aqueous dispersion of poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS). Due to the interconnected porous structure of MS, the conductive PEDOT:PSS@MS has a high compressibility and a stable piezoresistive response at the compressive strain up to 80%, as well as good reproducibility over 1000 cycles. Thereafter, versatile pressure sensors fabricated using the conductive PEDOT:PSS@MS sponges are attached to the different parts of human body; the capabilities of these devices to detect a variety of human motions including speaking, finger bending, elbow bending, and walking are evaluated. Furthermore, prototype tactile sensory array based on these pressure sensors is demonstrated.

  16. Method for Measuring the Volume-Scattering Function of Water

    NASA Technical Reports Server (NTRS)

    Agrawal, Yogesh C.

    2009-01-01

    The volume scattering function (VSF) of seawater affects visibility, remote sensing properties, in-water light propagation, lidar performance, and the like. Currently, it s possible to measure only small forward angles of VSF, or to use cumbersome, large, and non-autonomous systems. This innovation is a method of measuring the full range of VSF using a portable instrument. A single rapid-sensing photosensor is used to scan a green laser beam, which delivers the desired measurement. By using a single sensor, inter-calibration is avoided. A compact design is achieved by using drift-free detector electronics, fiber optics, and a new type of photomultiplier. This provides a high angular resolution of 1 or better, as well as the ability to focus in on a VSF region of particular interest. Currently, the total scattering of light is measured as a difference from the other two parts of the light budget equation. This innovation will allow the direct calculation of the total scattering of light by taking an integral of the VSF over all angles. This directly provides one of the three components of the light budget equation, allowing greater versatility in its calculation.

  17. Ultrawideband Electromagnetic Interference to Aircraft Radios: Results of Limited Functional Testing With United Airlines and Eagles Wings Incorporated, in Victorville, California

    NASA Technical Reports Server (NTRS)

    Ely, Jay J.; Shaver, Timothy W.; Fuller, Gerald L.

    2002-01-01

    On February 14, 2002, the FCC adopted a FIRST REPORT AND ORDER, released it on April 22, 2002, and on May 16, 2002 published in the Federal Register a Final Rule, permitting marketing and operation of new products incorporating UWB technology. Wireless product developers are working to rapidly bring this versatile, powerful and expectedly inexpensive technology into numerous consumer wireless devices. Past studies addressing the potential for passenger-carried portable electronic devices (PEDs) to interfere with aircraft electronic systems suggest that UWB transmitters may pose a significant threat to aircraft communication and navigation radio receivers. NASA, United Airlines and Eagles Wings Incorporated have performed preliminary testing that clearly shows the potential for handheld UWB transmitters to cause cockpit failure indications for the air traffic control radio beacon system (ATCRBS), blanking of aircraft on the traffic alert and collision avoidance system (TCAS) displays, and cause erratic motion and failure of instrument landing system (ILS) localizer and glideslope pointers on the pilot horizontal situation and attitude director displays. This report provides details of the preliminary testing and recommends further assessment of aircraft systems for susceptibility to UWB electromagnetic interference.

  18. Simulation-based cutaneous surgical-skill training on a chicken-skin bench model in a medical undergraduate program.

    PubMed

    Denadai, Rafael; Saad-Hossne, Rogério; Martinhão Souto, Luís Ricardo

    2013-05-01

    Because of ethical and medico-legal aspects involved in the training of cutaneous surgical skills on living patients, human cadavers and living animals, it is necessary the search for alternative and effective forms of training simulation. To propose and describe an alternative methodology for teaching and learning the principles of cutaneous surgery in a medical undergraduate program by using a chicken-skin bench model. One instructor for every four students, teaching materials on cutaneous surgical skills, chicken trunks, wings, or thighs, a rigid platform support, needled threads, needle holders, surgical blades with scalpel handles, rat-tooth tweezers, scissors, and marking pens were necessary for training simulation. A proposal for simulation-based training on incision, suture, biopsy, and on reconstruction techniques using a chicken-skin bench model distributed in several sessions and with increasing levels of difficultywas structured. Both feedback and objective evaluations always directed to individual students were also outlined. The teaching of a methodology for the principles of cutaneous surgery using a chicken-skin bench model versatile, portable, easy to assemble, and inexpensive is an alternative and complementary option to the armamentarium of methods based on other bench models described.

  19. Fundamentals, achievements and challenges in the electrochemical sensing of pathogens.

    PubMed

    Monzó, Javier; Insua, Ignacio; Fernandez-Trillo, Francisco; Rodriguez, Paramaconi

    2015-11-07

    Electrochemical sensors are powerful tools widely used in industrial, environmental and medical applications. The versatility of electrochemical methods allows for the investigation of chemical composition in real time and in situ. Electrochemical detection of specific biological molecules is a powerful means for detecting disease-related markers. In the last 10 years, highly-sensitive and specific methods have been developed to detect waterborne and foodborne pathogens. In this review, we classify the different electrochemical techniques used for the qualitative and quantitative detection of pathogens. The robustness of electrochemical methods allows for accurate detection even in heterogeneous and impure samples. We present a fundamental description of the three major electrochemical sensing methods used in the detection of pathogens and the advantages and disadvantages of each of these methods. In each section, we highlight recent breakthroughs, including the utilisation of microfluidics, immunomagnetic separation and multiplexing for the detection of multiple pathogens in a single device. We also include recent studies describing new strategies for the design of future immunosensing systems and protocols. The high sensitivity and selectivity, together with the portability and the cost-effectiveness of the instrumentation, enhances the demand for further development in the electrochemical detection of microbes.

  20. Integration of electrochemistry in micro-total analysis systems for biochemical assays: recent developments.

    PubMed

    Xu, Xiaoli; Zhang, Song; Chen, Hui; Kong, Jilie

    2009-11-15

    Micro-total analysis systems (microTAS) integrate different analytical operations like sample preparation, separation and detection into a single microfabricated device. With the outstanding advantages of low cost, satisfactory analytical efficiency and flexibility in design, highly integrated and miniaturized devices from the concept of microTAS have gained widespread applications, especially in biochemical assays. Electrochemistry is shown to be quite compatible with microanalytical systems for biochemical assays, because of its attractive merits such as simplicity, rapidity, high sensitivity, reduced power consumption, and sample/reagent economy. This review presents recent developments in the integration of electrochemistry in microdevices for biochemical assays. Ingenious microelectrode design and fabrication methods, and versatility of electrochemical techniques are involved. Practical applications of such integrated microsystem in biochemical assays are focused on in situ analysis, point-of-care testing and portable devices. Electrochemical techniques are apparently suited to microsystems, since easy microfabrication of electrochemical elements and a high degree of integration with multi-analytical functions can be achieved at low cost. Such integrated microsystems will play an increasingly important role for analysis of small volume biochemical samples. Work is in progress toward new microdevice design and applications.

  1. Plasma processes in the preparation of lithium-ion battery electrodes and separators

    NASA Astrophysics Data System (ADS)

    Nava-Avendaño, J.; Veilleux, J.

    2017-04-01

    Lithium-ion batteries (LIBs) are the energy storage devices that dominate the portable electronic market. They are now also considered and used for electric vehicles and are foreseen to enable the smart grid. Preparing batteries with high energy and power densities, elevated cycleability and improved safety could be achieved by controlling the microstructure of the electrode materials and the interaction they have with the electrolyte over the working potential window. Selecting appropriate precursors, reducing the preparation steps and selecting more efficient synthesis methods could also significantly reduce the costs of LIB components. Implementing plasma technologies can represent a high capital investment, but the versatility of the technologies allows the preparation of powdered nanoparticles with different morphologies, as well as with carbon and metal oxide coatings. Plasma technologies can also enable the preparation of binder-free thin films and coatings for LIB electrodes, and the treatment of polymeric membranes to be used as separators. This review paper aims at highlighting the different thermal and non-thermal plasma technologies recently used to synthesize coated and non-coated active materials for LIB cathodes and anodes, and to modify the surface of separators.

  2. Microfluidic-integrated biosensors: prospects for point-of-care diagnostics.

    PubMed

    Kumar, Suveen; Kumar, Saurabh; Ali, Md Azahar; Anand, Pinki; Agrawal, Ved Varun; John, Renu; Maji, Sagar; Malhotra, Bansi D

    2013-11-01

    There is a growing demand to integrate biosensors with microfluidics to provide miniaturized platforms with many favorable properties, such as reduced sample volume, decreased processing time, low cost analysis and low reagent consumption. These microfluidics-integrated biosensors would also have numerous advantages such as laminar flow, minimal handling of hazardous materials, multiple sample detection in parallel, portability and versatility in design. Microfluidics involves the science and technology of manipulation of fluids at the micro- to nano-liter level. It is predicted that combining biosensors with microfluidic chips will yield enhanced analytical capability, and widen the possibilities for applications in clinical diagnostics. The recent developments in microfluidics have helped researchers working in industries and educational institutes to adopt some of these platforms for point-of-care (POC) diagnostics. This review focuses on the latest advancements in the fields of microfluidic biosensing technologies, and on the challenges and possible solutions for translation of this technology for POC diagnostic applications. We also discuss the fabrication techniques required for developing microfluidic-integrated biosensors, recently reported biomarkers, and the prospects of POC diagnostics in the medical industry. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Agile Multi-Scale Decompositions for Automatic Image Registration

    NASA Technical Reports Server (NTRS)

    Murphy, James M.; Leija, Omar Navarro; Le Moigne, Jacqueline

    2016-01-01

    In recent works, the first and third authors developed an automatic image registration algorithm based on a multiscale hybrid image decomposition with anisotropic shearlets and isotropic wavelets. This prototype showed strong performance, improving robustness over registration with wavelets alone. However, this method imposed a strict hierarchy on the order in which shearlet and wavelet features were used in the registration process, and also involved an unintegrated mixture of MATLAB and C code. In this paper, we introduce a more agile model for generating features, in which a flexible and user-guided mix of shearlet and wavelet features are computed. Compared to the previous prototype, this method introduces a flexibility to the order in which shearlet and wavelet features are used in the registration process. Moreover, the present algorithm is now fully coded in C, making it more efficient and portable than the MATLAB and C prototype. We demonstrate the versatility and computational efficiency of this approach by performing registration experiments with the fully-integrated C algorithm. In particular, meaningful timing studies can now be performed, to give a concrete analysis of the computational costs of the flexible feature extraction. Examples of synthetically warped and real multi-modal images are analyzed.

  4. Use of Dimethyl Pimelimidate with Microfluidic System for Nucleic Acids Extraction without Electricity.

    PubMed

    Jin, Choong Eun; Lee, Tae Yoon; Koo, Bonhan; Choi, Kyung-Chul; Chang, Suhwan; Park, Se Yoon; Kim, Ji Yeun; Kim, Sung-Han; Shin, Yong

    2017-07-18

    The isolation of nucleic acids in the lab on a chip is crucial to achieve the maximal effectiveness of point-of-care testing for detection in clinical applications. Here, we report on the use of a simple and versatile single-channel microfluidic platform that combines dimethyl pimelimidate (DMP) for nucleic acids (both RNA and DNA) extraction without electricity using a thin-film system. The system is based on the adaption of DMP into nonchaotropic-based nucleic acids and the capture of reagents into a low-cost thin-film platform for use as a microfluidic total analysis system, which can be utilized for sample processing in clinical diagnostics. Moreover, we assessed the use of the DMP system for the extraction of nucleic acids from various samples, including mammalian cells, bacterial cells, and viruses from human disease, and we also confirmed that the quality and quantity of the nucleic acids extracted were sufficient to allow for the robust detection of biomarkers and/or pathogens in downstream analysis. Furthermore, this DMP system does not require any instruments and electricity, and has improved time efficiency, portability, and affordability. Thus, we believe that the DMP system may change the paradigm of sample processing in clinical diagnostics.

  5. Design and fabrication of a new electrolarynx and voice amplifier for laryngectomees.

    PubMed

    Sundeep Krishna, M; Jayanthy, A K; Divakar, C; Mekhala, R

    2005-01-01

    A Laryngectomee is a person whose vocal cords i.e. voice box is surgically removed owing to cancer or due to automobile accidents, burns or trauma. The patient, therefore permanently loses the ability to speak normally. An Electrolarynx is an electronic speech aid that enables the Laryngectomee to communicate with other people as quickly as possible after the successful removal of the larynx. A neck type Electrolarynx has been designed. Earlier designs could not alter frequency and intensity simultaneously during conversation. The Electrolarynx developed can control both frequency and intensity simultaneously during conversation. The device has been tested on the patient and found to be very effective. A portable, pocket size, battery powered voice amplifier (PA system) has also been developed which uses an electret condenser microphone as the input. The voice amplifier developed is a two stage amplifier which uses a preamplifier stage and a power amplifier stage. The output of the power amplifier is connected to a speaker. The device is being used by the patient and found to be very useful.

  6. Measuring frequency of spontaneous swallowing.

    PubMed

    Afkari, Sohail

    2007-12-01

    A new multi-sensory non-invasive portable system capable of detecting spontaneous swallowing in a patient population has been developed. Swallowing signals are recorded via Electromyogram (voltage potentials generated by throat muscles), an accelerometer (laryngeal elevations) and a microphone (cervical auscultation) affixed to the neck at the coniotomy region. Simultaneous signal comparison of all three modalities provides a vastly more reliable measure of swallowing frequency by rejecting artefacts associated with speech, body movement, coughing and background intereferences. The operational accuracy of the system was validated by a hand-held manual counter on a healthy subject undertaking everyday activities. Preliminary results showed a recorded mean spontaneous swallowing frequency of 1.32 swallows/minute and a slighly higher mean voluntary swallowing frequency of 1.52 swallows/minute with the intake of 100 ml of water. The device was able to detect 94.3% of dry swallows correctly, with each sensor responding differently to various noise interferences. The proposed system has potential to provide additional diagnostic information in clinical research of possible physiological problems associated with an abnormal swallowing frequency across a range of medical fields.

  7. 78 FR 49717 - Speech-to-Speech and Internet Protocol (IP) Speech-to-Speech Telecommunications Relay Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-15

    ...] Speech-to-Speech and Internet Protocol (IP) Speech-to-Speech Telecommunications Relay Services... Internet Protocol (IP) Speech-to-Speech Telecommunications Relay Services; Telecommunications Relay... (IP Relay) and video relay service (VRS), the Commission should bundle national STS outreach efforts...

  8. 47 CFR 90.1333 - Restrictions on the operation of mobile and portable stations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... transmitted by a base station. (b) Any mobile/portable stations may communicate with any other mobile/portable... by a base station. (c) Airborne operations by mobile/portable stations is prohibited. ... portable stations. 90.1333 Section 90.1333 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED...

  9. 46 CFR 182.458 - Portable fuel systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Portable fuel systems. 182.458 Section 182.458 Shipping...) MACHINERY INSTALLATION Specific Machinery Requirements § 182.458 Portable fuel systems. (a) Portable fuel systems, including portable tanks and related fuel lines and accessories, are prohibited except where used...

  10. 46 CFR 182.458 - Portable fuel systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Portable fuel systems. 182.458 Section 182.458 Shipping...) MACHINERY INSTALLATION Specific Machinery Requirements § 182.458 Portable fuel systems. (a) Portable fuel systems, including portable tanks and related fuel lines and accessories, are prohibited except where used...

  11. 46 CFR 182.458 - Portable fuel systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Portable fuel systems. 182.458 Section 182.458 Shipping...) MACHINERY INSTALLATION Specific Machinery Requirements § 182.458 Portable fuel systems. (a) Portable fuel systems, including portable tanks and related fuel lines and accessories, are prohibited except where used...

  12. 46 CFR 169.743 - Portable magazine chests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Portable magazine chests. 169.743 Section 169.743... Vessel Control, Miscellaneous Systems, and Equipment Markings § 169.743 Portable magazine chests. Portable magazine chests must be marked in letters at least 3 inches high: “PORTABLE MAGAZINE CHEST...

  13. Speech coding, reconstruction and recognition using acoustics and electromagnetic waves

    DOEpatents

    Holzrichter, J.F.; Ng, L.C.

    1998-03-17

    The use of EM radiation in conjunction with simultaneously recorded acoustic speech information enables a complete mathematical coding of acoustic speech. The methods include the forming of a feature vector for each pitch period of voiced speech and the forming of feature vectors for each time frame of unvoiced, as well as for combined voiced and unvoiced speech. The methods include how to deconvolve the speech excitation function from the acoustic speech output to describe the transfer function each time frame. The formation of feature vectors defining all acoustic speech units over well defined time frames can be used for purposes of speech coding, speech compression, speaker identification, language-of-speech identification, speech recognition, speech synthesis, speech translation, speech telephony, and speech teaching. 35 figs.

  14. Speech coding, reconstruction and recognition using acoustics and electromagnetic waves

    DOEpatents

    Holzrichter, John F.; Ng, Lawrence C.

    1998-01-01

    The use of EM radiation in conjunction with simultaneously recorded acoustic speech information enables a complete mathematical coding of acoustic speech. The methods include the forming of a feature vector for each pitch period of voiced speech and the forming of feature vectors for each time frame of unvoiced, as well as for combined voiced and unvoiced speech. The methods include how to deconvolve the speech excitation function from the acoustic speech output to describe the transfer function each time frame. The formation of feature vectors defining all acoustic speech units over well defined time frames can be used for purposes of speech coding, speech compression, speaker identification, language-of-speech identification, speech recognition, speech synthesis, speech translation, speech telephony, and speech teaching.

  15. Exploring Australian speech-language pathologists' use and perceptions ofnon-speech oral motor exercises.

    PubMed

    Rumbach, Anna F; Rose, Tanya A; Cheah, Mynn

    2018-01-29

    To explore Australian speech-language pathologists' use of non-speech oral motor exercises, and rationales for using/not using non-speech oral motor exercises in clinical practice. A total of 124 speech-language pathologists practising in Australia, working with paediatric and/or adult clients with speech sound difficulties, completed an online survey. The majority of speech-language pathologists reported that they did not use non-speech oral motor exercises when working with paediatric or adult clients with speech sound difficulties. However, more than half of the speech-language pathologists working with adult clients who have dysarthria reported using non-speech oral motor exercises with this population. The most frequently reported rationale for using non-speech oral motor exercises in speech sound difficulty management was to improve awareness/placement of articulators. The majority of speech-language pathologists agreed there is no clear clinical or research evidence base to support non-speech oral motor exercise use with clients who have speech sound difficulties. This study provides an overview of Australian speech-language pathologists' reported use and perceptions of non-speech oral motor exercises' applicability and efficacy in treating paediatric and adult clients who have speech sound difficulties. The research findings provide speech-language pathologists with insight into how and why non-speech oral motor exercises are currently used, and adds to the knowledge base regarding Australian speech-language pathology practice of non-speech oral motor exercises in the treatment of speech sound difficulties. Implications for Rehabilitation Non-speech oral motor exercises refer to oral motor activities which do not involve speech, but involve the manipulation or stimulation of oral structures including the lips, tongue, jaw, and soft palate. Non-speech oral motor exercises are intended to improve the function (e.g., movement, strength) of oral structures. The majority of speech-language pathologists agreed there is no clear clinical or research evidence base to support non-speech oral motor exercise use with clients who have speech sound disorders. Non-speech oral motor exercise use was most frequently reported in the treatment of dysarthria. Non-speech oral motor exercise use when targeting speech sound disorders is not widely endorsed in the literature.

  16. Design of a multifunctional and portable detector for indoor gases

    NASA Astrophysics Data System (ADS)

    Zhang, Liping; Wang, Yutian; Li, Taishan

    2003-09-01

    With the increase of the living standards of city dwellers, home decoration has been more and more popular these years. Different kinds of material have come into people's home, which brings about beauties to the house as well as some bad effect. Because of differences in manufacturing techniques and quality, much of the material will emit poisonous gases more or less. Even if you have selected the qualified product, the toal amount of gases in you houses may not be guaranteed because of the simple reason that more than one kind of material are applied. Living in the complex environment for a long time will eventually have a bad effect on one's health. In addition the fear of the harm to be done will exert great impact psychologically. In another aspect, the coal-gas in the house-hood for cooking is also explosive and poisonous. In conclusion, the research on the indoor hazardous gases measurement and alarm device is of much economic and practical importance. The device is portable and versatile. We use rechargeable battery as the power supply. The device can detect the density of gases at the ppb level for the emission of the material and the measured value can be shown on the display. As for coal gas it can detect the percentage of LEL and make sound of alarm. We use two kinds of gas-sensors in the device, with catalytic combustion principal for coal gas detection and the PID method for the gas emissions of the decoration material. UV will destroy harmful material (such as: ammonia, dimethylamine, methyl-sulfhydrate, benzene etc.) into positive or negative ions. The sensor detects the electric charges of ionized gases and converts them into electric current signals. It is then amplified and changed into digits by amplifier and A/D. The digit signal is processed by micro-controller system of the device.

  17. The Effects of Low-Intensity Therapeutic Ultrasound on Measurable Outcomes: A Critically Appraised Topic.

    PubMed

    Daniels, Sarah; Santiago, Gabriela; Cuchna, Jennifer; Van Lunen, Bonnie

    2018-06-21

    Clinical Scenario: Therapeutic ultrasound (US) is a popular modality among health care professionals and is used to treat a variety of musculoskeletal conditions. A new technology has been established to allow for the miniaturization of the US unit. Patients receive treatment with the device secured to them, eliminating the portability constraint of traditional US units. Early studies suggest that this portable unit can deliver low-intensity acoustic energy achieving the same temperature increase and pain relief that come from traditional US units, in a more versatile and patient-friendly manner. What effects does low-intensity therapeutic ultrasound (LITUS) have on measurable outcomes? Summary of Key Findings: The literature was searched for level 4 evidence or higher that investigated the effectiveness of LITUS. The literature search produced 3 possible studies related to the clinical question: 2 randomized controlled trials and 1 case series met the inclusion and exclusion criteria. Of the included studies, 1 study investigated the effects of LITUS on tissue temperature, 2 studies investigated the effects of LITUS on pain, and 1 study investigated LITUS effects on function. Clinical Bottom Line: The evidence supports the use of the LITUS unit to increase tissue temperature, decrease pain, and increase function. Therefore, practitioners may consider the use of the LITUS unit in patient populations over the use of the traditional high-intensity US treatment. Strength of Recommendation: In accordance with the 2009 Centre for Evidence-Based Medicine levels of evidence, there is grade I (insufficient) evidence to support the positive effects of the LITUS device for improving the following clinical outcomes: tissue temperature, decreasing pain, and increasing function. The inconsistency in the measured outcomes across the 3 studies only allows for minimal support of the LITUS device, warranting further research. Although clinical outcomes were different in each study, consistent evidence ranging from 4 to 1B levels were found in the 3 included studies.

  18. 30 CFR 18.35 - Portable (trailing) cables and cords.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Portable (trailing) cables and cords. 18.35... and Design Requirements § 18.35 Portable (trailing) cables and cords. (a) Portable cables and cords... a portable (trailing) cable shall not exceed 500 feet. Where the method of mining requires the...

  19. 46 CFR 195.11-30 - Portable tanks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Portable tanks. 195.11-30 Section 195.11-30 Shipping... AND MISCELLANEOUS SYSTEMS AND EQUIPMENT Portable Vans and Tanks § 195.11-30 Portable tanks. (a) All portable tanks, whether hazardous or nonhazardous commodities, shall be loaded and stowed in accordance...

  20. 46 CFR 195.11-30 - Portable tanks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Portable tanks. 195.11-30 Section 195.11-30 Shipping... AND MISCELLANEOUS SYSTEMS AND EQUIPMENT Portable Vans and Tanks § 195.11-30 Portable tanks. (a) All portable tanks, whether hazardous or nonhazardous commodities, shall be loaded and stowed in accordance...

  1. 46 CFR 195.11-30 - Portable tanks.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Portable tanks. 195.11-30 Section 195.11-30 Shipping... AND MISCELLANEOUS SYSTEMS AND EQUIPMENT Portable Vans and Tanks § 195.11-30 Portable tanks. (a) All portable tanks, whether hazardous or nonhazardous commodities, shall be loaded and stowed in accordance...

  2. 46 CFR 195.11-30 - Portable tanks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Portable tanks. 195.11-30 Section 195.11-30 Shipping... AND MISCELLANEOUS SYSTEMS AND EQUIPMENT Portable Vans and Tanks § 195.11-30 Portable tanks. (a) All portable tanks, whether hazardous or nonhazardous commodities, shall be loaded and stowed in accordance...

  3. 46 CFR 195.11-30 - Portable tanks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Portable tanks. 195.11-30 Section 195.11-30 Shipping... AND MISCELLANEOUS SYSTEMS AND EQUIPMENT Portable Vans and Tanks § 195.11-30 Portable tanks. (a) All portable tanks, whether hazardous or nonhazardous commodities, shall be loaded and stowed in accordance...

  4. 49 CFR 180.603 - Qualification of portable tanks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Qualification of portable tanks. 180.603 Section... MAINTENANCE OF PACKAGINGS Qualification and Maintenance of Portable Tanks § 180.603 Qualification of portable tanks. (a) Each portable tank used for the transportation of hazardous materials must be an authorized...

  5. 46 CFR 2.75-25 - Portable fire extinguishers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Portable fire extinguishers. 2.75-25 Section 2.75-25... Personnel § 2.75-25 Portable fire extinguishers. (a) The portable fire extinguishers listed and labeled as..., inclusive. (b) The procedures for manufacturers to follow and the requirements governing portable fire...

  6. 21 CFR 868.5655 - Portable liquid oxygen unit.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Portable liquid oxygen unit. 868.5655 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5655 Portable liquid oxygen unit. (a) Identification. A portable liquid oxygen unit is a portable, thermally insulated container of liquid oxygen that...

  7. 21 CFR 868.5655 - Portable liquid oxygen unit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Portable liquid oxygen unit. 868.5655 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5655 Portable liquid oxygen unit. (a) Identification. A portable liquid oxygen unit is a portable, thermally insulated container of liquid oxygen that...

  8. 21 CFR 868.5655 - Portable liquid oxygen unit.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Portable liquid oxygen unit. 868.5655 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5655 Portable liquid oxygen unit. (a) Identification. A portable liquid oxygen unit is a portable, thermally insulated container of liquid oxygen that...

  9. 21 CFR 868.5655 - Portable liquid oxygen unit.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Portable liquid oxygen unit. 868.5655 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5655 Portable liquid oxygen unit. (a) Identification. A portable liquid oxygen unit is a portable, thermally insulated container of liquid oxygen that...

  10. 21 CFR 868.5655 - Portable liquid oxygen unit.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Portable liquid oxygen unit. 868.5655 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5655 Portable liquid oxygen unit. (a) Identification. A portable liquid oxygen unit is a portable, thermally insulated container of liquid oxygen that...

  11. 46 CFR 108.651 - Portable magazine chests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Portable magazine chests. 108.651 Section 108.651... AND EQUIPMENT Equipment Markings and Instructions § 108.651 Portable magazine chests. Each portable magazine chest must be marked: “PORTABLE MAGAZINE CHEST—FLAMMABLE—KEEP LIGHTS AND FIRE AWAY” in letters at...

  12. 47 CFR 80.1189 - Portable ship earth stations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Portable ship earth stations. 80.1189 Section....1189 Portable ship earth stations. (a) Portable ship earth stations are authorized to operate on board more than one ship. Portable ship earth stations are also authorized to be operated on board fixed...

  13. 47 CFR 80.1189 - Portable ship earth stations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Portable ship earth stations. 80.1189 Section....1189 Portable ship earth stations. (a) Portable ship earth stations are authorized to operate on board more than one ship. Portable ship earth stations are also authorized to be operated on board fixed...

  14. 47 CFR 80.1189 - Portable ship earth stations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Portable ship earth stations. 80.1189 Section....1189 Portable ship earth stations. (a) Portable ship earth stations are authorized to operate on board more than one ship. Portable ship earth stations are also authorized to be operated on board fixed...

  15. 47 CFR 80.1189 - Portable ship earth stations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Portable ship earth stations. 80.1189 Section....1189 Portable ship earth stations. (a) Portable ship earth stations are authorized to operate on board more than one ship. Portable ship earth stations are also authorized to be operated on board fixed...

  16. 47 CFR 80.1189 - Portable ship earth stations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Portable ship earth stations. 80.1189 Section....1189 Portable ship earth stations. (a) Portable ship earth stations are authorized to operate on board more than one ship. Portable ship earth stations are also authorized to be operated on board fixed...

  17. 29 CFR 1915.172 - Portable air receivers and other unfired pressure vessels.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Portable air receivers and other unfired pressure vessels... SHIPYARD EMPLOYMENT Portable, Unfired Pressure Vessels, Drums and Containers, Other Than Ship's Equipment § 1915.172 Portable air receivers and other unfired pressure vessels. (a) Portable, unfired pressure...

  18. 29 CFR 1915.172 - Portable air receivers and other unfired pressure vessels.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Portable air receivers and other unfired pressure vessels... SHIPYARD EMPLOYMENT Portable, Unfired Pressure Vessels, Drums and Containers, Other Than Ship's Equipment § 1915.172 Portable air receivers and other unfired pressure vessels. (a) Portable, unfired pressure...

  19. 29 CFR 1915.172 - Portable air receivers and other unfired pressure vessels.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Portable air receivers and other unfired pressure vessels... SHIPYARD EMPLOYMENT Portable, Unfired Pressure Vessels, Drums and Containers, Other Than Ship's Equipment § 1915.172 Portable air receivers and other unfired pressure vessels. (a) Portable, unfired pressure...

  20. Speech coding, reconstruction and recognition using acoustics and electromagnetic waves

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holzrichter, J.F.; Ng, L.C.

    The use of EM radiation in conjunction with simultaneously recorded acoustic speech information enables a complete mathematical coding of acoustic speech. The methods include the forming of a feature vector for each pitch period of voiced speech and the forming of feature vectors for each time frame of unvoiced, as well as for combined voiced and unvoiced speech. The methods include how to deconvolve the speech excitation function from the acoustic speech output to describe the transfer function each time frame. The formation of feature vectors defining all acoustic speech units over well defined time frames can be used formore » purposes of speech coding, speech compression, speaker identification, language-of-speech identification, speech recognition, speech synthesis, speech translation, speech telephony, and speech teaching. 35 figs.« less

  1. Medicine clerkships and portable computing: a national survey of internal medicine clerkship directors.

    PubMed

    Ferenchick, Gary; Solomon, David; Durning, Steven J

    2010-01-01

    Portable computers are widely used by medical trainees, but there is a lack of data on how these devices are used in clinical education programs. The objective is to define the current use of portable computing in internal medicine clerkships and to determine medicine clerkship directors' perceptions of the current value and future importance of portable computing. A 2006 national survey of institutional members of the Clerkship Directors in Internal Medicine. Eighty-three of 110 (75%) of institutional members responded. An institutional requirement for portable computing was reported by 32 schools (39%), whereas only 13 (16%) provided students with a portable computer. Between 10 and 31 institutions (12-37%) reported student use for patient care activities (i.e. order entry, writing patient notes) and only 2 to 4 institutions (2-5%) required such use. The majority of respondents (59-95%) reported portable computer use for educational activities (i.e., tracking patient problems, knowledge resource), however, only in 5 to 19 (6-23%) were such educational uses required. Fifty-six respondents (68%) reported that portable computer's "added value" for teaching and 61 (73%) reported that portable computers would be important in meeting clerkship objectives in the next 3 years. Of interest, even among the institutions requiring portable computers, only 50% recommended or required specific software. Portable computing is required at 39% of allopathic medical schools in the United States. However required portable computing for specific patient care or educational tasks is uncommon. In addition, guidance on specific software exists in only one half of school requiring portable computers, suggesting informal or unstructured uses of required portable computer's in the remaining half. The educational impact of formal institutional requirements for software versus informal "user-defined" applications is unknown.

  2. 29 CFR 1917.119 - Portable ladders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) MARINE TERMINALS Terminal Facilities § 1917.119 Portable ladders. (a) Scope and applicability... Requirements for Portable Reinforced Plastic Ladders (d) Standards for job-made portable ladders. Job-made...

  3. 49 CFR 173.32 - Requirements for the use of portable tanks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... portable tanks. (1) The bursting strength of any piping and fittings must be at least four times the design... specified portable tank must meet the same design profile; for example, a DOT Specification 51 portable tank... manufactured portable tanks must conform to the requirements for the design, construction and approval of UN...

  4. 40 CFR 59.615 - How must I label and identify the portable fuel containers I produce?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... portable fuel containers I produce? 59.615 Section 59.615 Protection of Environment ENVIRONMENTAL... FOR CONSUMER AND COMMERCIAL PRODUCTS Control of Evaporative Emissions From New and In-Use Portable... portable fuel containers I produce? This section describes how you must label your portable fuel containers...

  5. 46 CFR 78.47-70 - Portable magazine chests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Portable magazine chests. 78.47-70 Section 78.47-70... Fire and Emergency Equipment, Etc. § 78.47-70 Portable magazine chests. (a) Portable magazine chest shall be marked in letters of at least 3 inches high “PORTABLE MAGAZINE CHEST—FLAMMABLE—KEEP LIGHTS AND...

  6. 46 CFR 97.37-47 - Portable magazine chests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Portable magazine chests. 97.37-47 Section 97.37-47... OPERATIONS Markings for Fire and Emergency Equipment, Etc. § 97.37-47 Portable magazine chests. (a) Portable magazine chests shall be marked in letters at least 3 inches high: “PORTABLE MAGAZINE CHEST—FLAMMABLE—KEEP...

  7. 46 CFR 196.37-47 - Portable magazine chests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Portable magazine chests. 196.37-47 Section 196.37-47... Markings for Fire and Emergency Equipment, etc. § 196.37-47 Portable magazine chests. (a) Portable magazine chests shall be marked in letters at least 3 inches high: PORTABLE MAGAZINE CHEST — FLAMMABLE — KEEP...

  8. Design criteria for portable timber bridge systems : static versus dynamic loads

    Treesearch

    John M. Franklin; S. E. Taylor; Paul A. Morgan; M. A. Ritter

    1999-01-01

    Design criteria are needed specifically for portable bridges to insure that they are safe and cost effective. This paper discusses different portable bridge categories and their general design criteria. Specific emphasis is given to quantifying the effects of dynamic live loads on portable bridge design. Results from static and dynamic load tests of two portable timber...

  9. Speech processing using maximum likelihood continuity mapping

    DOEpatents

    Hogden, John E.

    2000-01-01

    Speech processing is obtained that, given a probabilistic mapping between static speech sounds and pseudo-articulator positions, allows sequences of speech sounds to be mapped to smooth sequences of pseudo-articulator positions. In addition, a method for learning a probabilistic mapping between static speech sounds and pseudo-articulator position is described. The method for learning the mapping between static speech sounds and pseudo-articulator position uses a set of training data composed only of speech sounds. The said speech processing can be applied to various speech analysis tasks, including speech recognition, speaker recognition, speech coding, speech synthesis, and voice mimicry.

  10. Speech processing using maximum likelihood continuity mapping

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hogden, J.E.

    Speech processing is obtained that, given a probabilistic mapping between static speech sounds and pseudo-articulator positions, allows sequences of speech sounds to be mapped to smooth sequences of pseudo-articulator positions. In addition, a method for learning a probabilistic mapping between static speech sounds and pseudo-articulator position is described. The method for learning the mapping between static speech sounds and pseudo-articulator position uses a set of training data composed only of speech sounds. The said speech processing can be applied to various speech analysis tasks, including speech recognition, speaker recognition, speech coding, speech synthesis, and voice mimicry.

  11. Schizophrenia alters intra-network functional connectivity in the caudate for detecting speech under informational speech masking conditions.

    PubMed

    Zheng, Yingjun; Wu, Chao; Li, Juanhua; Li, Ruikeng; Peng, Hongjun; She, Shenglin; Ning, Yuping; Li, Liang

    2018-04-04

    Speech recognition under noisy "cocktail-party" environments involves multiple perceptual/cognitive processes, including target detection, selective attention, irrelevant signal inhibition, sensory/working memory, and speech production. Compared to health listeners, people with schizophrenia are more vulnerable to masking stimuli and perform worse in speech recognition under speech-on-speech masking conditions. Although the schizophrenia-related speech-recognition impairment under "cocktail-party" conditions is associated with deficits of various perceptual/cognitive processes, it is crucial to know whether the brain substrates critically underlying speech detection against informational speech masking are impaired in people with schizophrenia. Using functional magnetic resonance imaging (fMRI), this study investigated differences between people with schizophrenia (n = 19, mean age = 33 ± 10 years) and their matched healthy controls (n = 15, mean age = 30 ± 9 years) in intra-network functional connectivity (FC) specifically associated with target-speech detection under speech-on-speech-masking conditions. The target-speech detection performance under the speech-on-speech-masking condition in participants with schizophrenia was significantly worse than that in matched healthy participants (healthy controls). Moreover, in healthy controls, but not participants with schizophrenia, the strength of intra-network FC within the bilateral caudate was positively correlated with the speech-detection performance under the speech-masking conditions. Compared to controls, patients showed altered spatial activity pattern and decreased intra-network FC in the caudate. In people with schizophrenia, the declined speech-detection performance under speech-on-speech masking conditions is associated with reduced intra-caudate functional connectivity, which normally contributes to detecting target speech against speech masking via its functions of suppressing masking-speech signals.

  12. DLR MiroSurge: a versatile system for research in endoscopic telesurgery.

    PubMed

    Hagn, Ulrich; Konietschke, R; Tobergte, A; Nickl, M; Jörg, S; Kübler, B; Passig, G; Gröger, M; Fröhlich, F; Seibold, U; Le-Tien, L; Albu-Schäffer, A; Nothhelfer, A; Hacker, F; Grebenstein, M; Hirzinger, G

    2010-03-01

    Research on surgical robotics demands systems for evaluating scientific approaches. Such systems can be divided into dedicated and versatile systems. Dedicated systems are designed for a single surgical task or technique, whereas versatile systems are designed to be expandable and useful in multiple surgical applications. Versatile systems are often based on industrial robots, though, and because of this, are hardly suitable for close contact with humans. To achieve a high degree of versatility the Miro robotic surgery platform (MRSP) consists of versatile components, dedicated front-ends towards surgery and configurable interfaces for the surgeon. This paper presents MiroSurge, a configuration of the MRSP that allows for bimanual endoscopic telesurgery with force feedback. While the components of the MiroSurge system are shown to fulfil the rigid design requirements for robotic telesurgery with force feedback, the system remains versatile, which is supposed to be a key issue for the further development and optimisation.

  13. 76 FR 31362 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Versatile Onboard...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... Production Act of 1993--Versatile Onboard Traffic Embedded Roaming Sensors (Formerly Joint Venture To Perform Project Entitled Versatile Onboard Traffic Embedded Roaming Sensors) Notice is hereby given that, on April..., 15 U.S.C. 4301 et seq. (``the Act''), Versatile Onboard Traffic Embedded Roaming Sensors (formerly...

  14. 40 CFR 59.653 - How do I test portable fuel containers?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 6 2012-07-01 2012-07-01 false How do I test portable fuel containers... Families § 59.653 How do I test portable fuel containers? You must test the portable fuel container as.... Perform a slosh test by filling the portable fuel container to 40 percent of its capacity with the fuel...

  15. 40 CFR 59.653 - How do I test portable fuel containers?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 6 2013-07-01 2013-07-01 false How do I test portable fuel containers... Families § 59.653 How do I test portable fuel containers? You must test the portable fuel container as.... Perform a slosh test by filling the portable fuel container to 40 percent of its capacity with the fuel...

  16. 40 CFR 59.653 - How do I test portable fuel containers?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 6 2014-07-01 2014-07-01 false How do I test portable fuel containers... Families § 59.653 How do I test portable fuel containers? You must test the portable fuel container as.... Perform a slosh test by filling the portable fuel container to 40 percent of its capacity with the fuel...

  17. The Relationship Between Speech Production and Speech Perception Deficits in Parkinson's Disease.

    PubMed

    De Keyser, Kim; Santens, Patrick; Bockstael, Annelies; Botteldooren, Dick; Talsma, Durk; De Vos, Stefanie; Van Cauwenberghe, Mieke; Verheugen, Femke; Corthals, Paul; De Letter, Miet

    2016-10-01

    This study investigated the possible relationship between hypokinetic speech production and speech intensity perception in patients with Parkinson's disease (PD). Participants included 14 patients with idiopathic PD and 14 matched healthy controls (HCs) with normal hearing and cognition. First, speech production was objectified through a standardized speech intelligibility assessment, acoustic analysis, and speech intensity measurements. Second, an overall estimation task and an intensity estimation task were addressed to evaluate overall speech perception and speech intensity perception, respectively. Finally, correlation analysis was performed between the speech characteristics of the overall estimation task and the corresponding acoustic analysis. The interaction between speech production and speech intensity perception was investigated by an intensity imitation task. Acoustic analysis and speech intensity measurements demonstrated significant differences in speech production between patients with PD and the HCs. A different pattern in the auditory perception of speech and speech intensity was found in the PD group. Auditory perceptual deficits may influence speech production in patients with PD. The present results suggest a disturbed auditory perception related to an automatic monitoring deficit in PD.

  18. Visual Context Enhanced: The Joint Contribution of Iconic Gestures and Visible Speech to Degraded Speech Comprehension.

    PubMed

    Drijvers, Linda; Özyürek, Asli

    2017-01-01

    This study investigated whether and to what extent iconic co-speech gestures contribute to information from visible speech to enhance degraded speech comprehension at different levels of noise-vocoding. Previous studies of the contributions of these 2 visual articulators to speech comprehension have only been performed separately. Twenty participants watched videos of an actress uttering an action verb and completed a free-recall task. The videos were presented in 3 speech conditions (2-band noise-vocoding, 6-band noise-vocoding, clear), 3 multimodal conditions (speech + lips blurred, speech + visible speech, speech + visible speech + gesture), and 2 visual-only conditions (visible speech, visible speech + gesture). Accuracy levels were higher when both visual articulators were present compared with 1 or none. The enhancement effects of (a) visible speech, (b) gestural information on top of visible speech, and (c) both visible speech and iconic gestures were larger in 6-band than 2-band noise-vocoding or visual-only conditions. Gestural enhancement in 2-band noise-vocoding did not differ from gestural enhancement in visual-only conditions. When perceiving degraded speech in a visual context, listeners benefit more from having both visual articulators present compared with 1. This benefit was larger at 6-band than 2-band noise-vocoding, where listeners can benefit from both phonological cues from visible speech and semantic cues from iconic gestures to disambiguate speech.

  19. Comprehension of synthetic speech and digitized natural speech by adults with aphasia.

    PubMed

    Hux, Karen; Knollman-Porter, Kelly; Brown, Jessica; Wallace, Sarah E

    2017-09-01

    Using text-to-speech technology to provide simultaneous written and auditory content presentation may help compensate for chronic reading challenges if people with aphasia can understand synthetic speech output; however, inherent auditory comprehension challenges experienced by people with aphasia may make understanding synthetic speech difficult. This study's purpose was to compare the preferences and auditory comprehension accuracy of people with aphasia when listening to sentences generated with digitized natural speech, Alex synthetic speech (i.e., Macintosh platform), or David synthetic speech (i.e., Windows platform). The methodology required each of 20 participants with aphasia to select one of four images corresponding in meaning to each of 60 sentences comprising three stimulus sets. Results revealed significantly better accuracy given digitized natural speech than either synthetic speech option; however, individual participant performance analyses revealed three patterns: (a) comparable accuracy regardless of speech condition for 30% of participants, (b) comparable accuracy between digitized natural speech and one, but not both, synthetic speech option for 45% of participants, and (c) greater accuracy with digitized natural speech than with either synthetic speech option for remaining participants. Ranking and Likert-scale rating data revealed a preference for digitized natural speech and David synthetic speech over Alex synthetic speech. Results suggest many individuals with aphasia can comprehend synthetic speech options available on popular operating systems. Further examination of synthetic speech use to support reading comprehension through text-to-speech technology is thus warranted. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Portable Medical Laboratory Applications Software

    PubMed Central

    Silbert, Jerome A.

    1983-01-01

    Portability implies that a program can be run on a variety of computers with minimal software revision. The advantages of portability are outlined and design considerations for portable laboratory software are discussed. Specific approaches for achieving this goal are presented.

  1. Non-fluent speech following stroke is caused by impaired efference copy.

    PubMed

    Feenaughty, Lynda; Basilakos, Alexandra; Bonilha, Leonardo; den Ouden, Dirk-Bart; Rorden, Chris; Stark, Brielle; Fridriksson, Julius

    2017-09-01

    Efference copy is a cognitive mechanism argued to be critical for initiating and monitoring speech: however, the extent to which breakdown of efference copy mechanisms impact speech production is unclear. This study examined the best mechanistic predictors of non-fluent speech among 88 stroke survivors. Objective speech fluency measures were subjected to a principal component analysis (PCA). The primary PCA factor was then entered into a multiple stepwise linear regression analysis as the dependent variable, with a set of independent mechanistic variables. Participants' ability to mimic audio-visual speech ("speech entrainment response") was the best independent predictor of non-fluent speech. We suggest that this "speech entrainment" factor reflects integrity of internal monitoring (i.e., efference copy) of speech production, which affects speech initiation and maintenance. Results support models of normal speech production and suggest that therapy focused on speech initiation and maintenance may improve speech fluency for individuals with chronic non-fluent aphasia post stroke.

  2. Autistic traits and attention to speech: Evidence from typically developing individuals.

    PubMed

    Korhonen, Vesa; Werner, Stefan

    2017-04-01

    Individuals with autism spectrum disorder have a preference for attending to non-speech stimuli over speech stimuli. We are interested in whether non-speech preference is only a feature of diagnosed individuals, and whether we can we test implicit preference experimentally. In typically developed individuals, serial recall is disrupted more by speech stimuli than by non-speech stimuli. Since behaviour of individuals with autistic traits resembles that of individuals with autism, we have used serial recall to test whether autistic traits influence task performance during irrelevant speech sounds. The errors made on the serial recall task during speech or non-speech sounds were counted as a measure of speech or non-speech preference in relation to no sound condition. We replicated the serial order effect and found the speech to be more disruptive than the non-speech sounds, but were unable to find any associations between the autism quotient scores and the non-speech sounds. Our results may indicate a learnt behavioural response to speech sounds.

  3. Electrophysiological evidence for speech-specific audiovisual integration.

    PubMed

    Baart, Martijn; Stekelenburg, Jeroen J; Vroomen, Jean

    2014-01-01

    Lip-read speech is integrated with heard speech at various neural levels. Here, we investigated the extent to which lip-read induced modulations of the auditory N1 and P2 (measured with EEG) are indicative of speech-specific audiovisual integration, and we explored to what extent the ERPs were modulated by phonetic audiovisual congruency. In order to disentangle speech-specific (phonetic) integration from non-speech integration, we used Sine-Wave Speech (SWS) that was perceived as speech by half of the participants (they were in speech-mode), while the other half was in non-speech mode. Results showed that the N1 obtained with audiovisual stimuli peaked earlier than the N1 evoked by auditory-only stimuli. This lip-read induced speeding up of the N1 occurred for listeners in speech and non-speech mode. In contrast, if listeners were in speech-mode, lip-read speech also modulated the auditory P2, but not if listeners were in non-speech mode, thus revealing speech-specific audiovisual binding. Comparing ERPs for phonetically congruent audiovisual stimuli with ERPs for incongruent stimuli revealed an effect of phonetic stimulus congruency that started at ~200 ms after (in)congruence became apparent. Critically, akin to the P2 suppression, congruency effects were only observed if listeners were in speech mode, and not if they were in non-speech mode. Using identical stimuli, we thus confirm that audiovisual binding involves (partially) different neural mechanisms for sound processing in speech and non-speech mode. © 2013 Published by Elsevier Ltd.

  4. Inner Speech's Relationship With Overt Speech in Poststroke Aphasia.

    PubMed

    Stark, Brielle C; Geva, Sharon; Warburton, Elizabeth A

    2017-09-18

    Relatively preserved inner speech alongside poor overt speech has been documented in some persons with aphasia (PWA), but the relationship of overt speech with inner speech is still largely unclear, as few studies have directly investigated these factors. The present study investigates the relationship of relatively preserved inner speech in aphasia with selected measures of language and cognition. Thirty-eight persons with chronic aphasia (27 men, 11 women; average age 64.53 ± 13.29 years, time since stroke 8-111 months) were classified as having relatively preserved inner and overt speech (n = 21), relatively preserved inner speech with poor overt speech (n = 8), or not classified due to insufficient measurements of inner and/or overt speech (n = 9). Inner speech scores (by group) were correlated with selected measures of language and cognition from the Comprehensive Aphasia Test (Swinburn, Porter, & Al, 2004). The group with poor overt speech showed a significant relationship of inner speech with overt naming (r = .95, p < .01) and with mean length of utterance produced during a written picture description (r = .96, p < .01). Correlations between inner speech and language and cognition factors were not significant for the group with relatively good overt speech. As in previous research, we show that relatively preserved inner speech is found alongside otherwise severe production deficits in PWA. PWA with poor overt speech may rely more on preserved inner speech for overt picture naming (perhaps due to shared resources with verbal working memory) and for written picture description (perhaps due to reliance on inner speech due to perceived task difficulty). Assessments of inner speech may be useful as a standard component of aphasia screening, and therapy focused on improving and using inner speech may prove clinically worthwhile. https://doi.org/10.23641/asha.5303542.

  5. Atypical speech versus non-speech detection and discrimination in 4- to 6- yr old children with autism spectrum disorder: An ERP study.

    PubMed

    Galilee, Alena; Stefanidou, Chrysi; McCleery, Joseph P

    2017-01-01

    Previous event-related potential (ERP) research utilizing oddball stimulus paradigms suggests diminished processing of speech versus non-speech sounds in children with an Autism Spectrum Disorder (ASD). However, brain mechanisms underlying these speech processing abnormalities, and to what extent they are related to poor language abilities in this population remain unknown. In the current study, we utilized a novel paired repetition paradigm in order to investigate ERP responses associated with the detection and discrimination of speech and non-speech sounds in 4- to 6-year old children with ASD, compared with gender and verbal age matched controls. ERPs were recorded while children passively listened to pairs of stimuli that were either both speech sounds, both non-speech sounds, speech followed by non-speech, or non-speech followed by speech. Control participants exhibited N330 match/mismatch responses measured from temporal electrodes, reflecting speech versus non-speech detection, bilaterally, whereas children with ASD exhibited this effect only over temporal electrodes in the left hemisphere. Furthermore, while the control groups exhibited match/mismatch effects at approximately 600 ms (central N600, temporal P600) when a non-speech sound was followed by a speech sound, these effects were absent in the ASD group. These findings suggest that children with ASD fail to activate right hemisphere mechanisms, likely associated with social or emotional aspects of speech detection, when distinguishing non-speech from speech stimuli. Together, these results demonstrate the presence of atypical speech versus non-speech processing in children with ASD when compared with typically developing children matched on verbal age.

  6. Atypical speech versus non-speech detection and discrimination in 4- to 6- yr old children with autism spectrum disorder: An ERP study

    PubMed Central

    Stefanidou, Chrysi; McCleery, Joseph P.

    2017-01-01

    Previous event-related potential (ERP) research utilizing oddball stimulus paradigms suggests diminished processing of speech versus non-speech sounds in children with an Autism Spectrum Disorder (ASD). However, brain mechanisms underlying these speech processing abnormalities, and to what extent they are related to poor language abilities in this population remain unknown. In the current study, we utilized a novel paired repetition paradigm in order to investigate ERP responses associated with the detection and discrimination of speech and non-speech sounds in 4- to 6—year old children with ASD, compared with gender and verbal age matched controls. ERPs were recorded while children passively listened to pairs of stimuli that were either both speech sounds, both non-speech sounds, speech followed by non-speech, or non-speech followed by speech. Control participants exhibited N330 match/mismatch responses measured from temporal electrodes, reflecting speech versus non-speech detection, bilaterally, whereas children with ASD exhibited this effect only over temporal electrodes in the left hemisphere. Furthermore, while the control groups exhibited match/mismatch effects at approximately 600 ms (central N600, temporal P600) when a non-speech sound was followed by a speech sound, these effects were absent in the ASD group. These findings suggest that children with ASD fail to activate right hemisphere mechanisms, likely associated with social or emotional aspects of speech detection, when distinguishing non-speech from speech stimuli. Together, these results demonstrate the presence of atypical speech versus non-speech processing in children with ASD when compared with typically developing children matched on verbal age. PMID:28738063

  7. 47 CFR 51.203 - Number portability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Number portability. 51.203 Section 51.203 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERCONNECTION Obligations of All Local Exchange Carriers § 51.203 Number portability. The rules governing number portability...

  8. 47 CFR 51.203 - Number portability.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false Number portability. 51.203 Section 51.203 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERCONNECTION Obligations of All Local Exchange Carriers § 51.203 Number portability. The rules governing number portability...

  9. 47 CFR 51.203 - Number portability.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Number portability. 51.203 Section 51.203 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERCONNECTION Obligations of All Local Exchange Carriers § 51.203 Number portability. The rules governing number portability...

  10. 47 CFR 51.203 - Number portability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Number portability. 51.203 Section 51.203 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERCONNECTION Obligations of All Local Exchange Carriers § 51.203 Number portability. The rules governing number portability...

  11. 47 CFR 51.203 - Number portability.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Number portability. 51.203 Section 51.203 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERCONNECTION Obligations of All Local Exchange Carriers § 51.203 Number portability. The rules governing number portability...

  12. The Impact of Rechargeable Batteries: Quantifying the Cost and Weight for a Marine Infantry Battalion

    DTIC Science & Technology

    2011-12-01

    Suitcase Portable Charger (SPC), Vehicle - Mounted Charger (VMC), Solar Portable Power System (SPACES) 15. NUMBER OF PAGES 77 16. PRICE CODE 17...battery (MCCOC, 2010): the Soldier Portable Charger (SPC), the Vehicle Mounted Charger (VMC), and the Solar Portable Alternative Communication Energy...Suitcase Portable Charger TO&E Table of Organization and Equipment UHF Ultra High Frequency VHF Very High Frequency VMC Vehicle Mounted

  13. Expanding Applications of SERS through Versatile Nanomaterials Engineering (Postprint)

    DTIC Science & Technology

    2017-06-22

    AFRL-RX-WP-JA-2017-0341 EXPANDING APPLICATIONS OF SERS THROUGH VERSATILE NANOMATERIALS ENGINEERING (POSTPRINT) M. Fernanda...AND SUBTITLE EXPANDING APPLICATIONS OF SERS THROUGH VERSATILE NANOMATERIALS ENGINEERING (POSTPRINT) 5a. CONTRACT NUMBER FA8650-15-2-5518 5b...Expanding applications of SERS through versatile nanomaterials engineering M. Fernanda Cardinal, Emma Vander Ende, Ryan A. Hackler, Michael O. McAnally

  14. Speech Clarity Index (Ψ): A Distance-Based Speech Quality Indicator and Recognition Rate Prediction for Dysarthric Speakers with Cerebral Palsy

    NASA Astrophysics Data System (ADS)

    Kayasith, Prakasith; Theeramunkong, Thanaruk

    It is a tedious and subjective task to measure severity of a dysarthria by manually evaluating his/her speech using available standard assessment methods based on human perception. This paper presents an automated approach to assess speech quality of a dysarthric speaker with cerebral palsy. With the consideration of two complementary factors, speech consistency and speech distinction, a speech quality indicator called speech clarity index (Ψ) is proposed as a measure of the speaker's ability to produce consistent speech signal for a certain word and distinguished speech signal for different words. As an application, it can be used to assess speech quality and forecast speech recognition rate of speech made by an individual dysarthric speaker before actual exhaustive implementation of an automatic speech recognition system for the speaker. The effectiveness of Ψ as a speech recognition rate predictor is evaluated by rank-order inconsistency, correlation coefficient, and root-mean-square of difference. The evaluations had been done by comparing its predicted recognition rates with ones predicted by the standard methods called the articulatory and intelligibility tests based on the two recognition systems (HMM and ANN). The results show that Ψ is a promising indicator for predicting recognition rate of dysarthric speech. All experiments had been done on speech corpus composed of speech data from eight normal speakers and eight dysarthric speakers.

  15. Motor Speech Phenotypes of Frontotemporal Dementia, Primary Progressive Aphasia, and Progressive Apraxia of Speech.

    PubMed

    Poole, Matthew L; Brodtmann, Amy; Darby, David; Vogel, Adam P

    2017-04-14

    Our purpose was to create a comprehensive review of speech impairment in frontotemporal dementia (FTD), primary progressive aphasia (PPA), and progressive apraxia of speech in order to identify the most effective measures for diagnosis and monitoring, and to elucidate associations between speech and neuroimaging. Speech and neuroimaging data described in studies of FTD and PPA were systematically reviewed. A meta-analysis was conducted for speech measures that were used consistently in multiple studies. The methods and nomenclature used to describe speech in these disorders varied between studies. Our meta-analysis identified 3 speech measures which differentiate variants or healthy control-group participants (e.g., nonfluent and logopenic variants of PPA from all other groups, behavioral-variant FTD from a control group). Deficits within the frontal-lobe speech networks are linked to motor speech profiles of the nonfluent variant of PPA and progressive apraxia of speech. Motor speech impairment is rarely reported in semantic and logopenic variants of PPA. Limited data are available on motor speech impairment in the behavioral variant of FTD. Our review identified several measures of speech which may assist with diagnosis and classification, and consolidated the brain-behavior associations relating to speech in FTD, PPA, and progressive apraxia of speech.

  16. System and method for characterizing voiced excitations of speech and acoustic signals, removing acoustic noise from speech, and synthesizing speech

    DOEpatents

    Burnett, Greg C.; Holzrichter, John F.; Ng, Lawrence C.

    2002-01-01

    Low power EM waves are used to detect motions of vocal tract tissues of the human speech system before, during, and after voiced speech. A voiced excitation function is derived. The excitation function provides speech production information to enhance speech characterization and to enable noise removal from human speech.

  17. Operations manual for portable profiler : installing and using the portable profiler.

    DOT National Transportation Integrated Search

    2010-06-01

    This manual is divided into two sections. The first is using the UTA-Profiler Program : with the portable profiler for generating surface profilers. The second is installing the : portable profiler module on a typical van or truck. The calibration an...

  18. 77 FR 4219 - FAA-Approved Portable Oxygen Concentrators; Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-27

    ...-1343; Amdt. No. 121-358] FAA-Approved Portable Oxygen Concentrators; Technical Amendment AGENCY... amending regulations relating to operating rules for FAA approved portable oxygen concentrators (POC... Certain Portable Oxygen Concentrator Devices Onboard Aircraft'' (70 FR 40156). SFAR 106 permits passengers...

  19. 48 CFR 1837.170 - Pension portability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Pension portability. 1837... ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Service Contracts-General 1837.170 Pension portability. (a) It is NASA's policy not to require pension portability in service contracts. However, pension...

  20. 49 CFR 178.255 - Specification 60; steel portable tanks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Specification 60; steel portable tanks. 178.255 Section 178.255 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND... PACKAGINGS Specifications for Portable Tanks § 178.255 Specification 60; steel portable tanks. ...

  1. 49 CFR 178.255 - Specification 60; steel portable tanks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Specification 60; steel portable tanks. 178.255 Section 178.255 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND... PACKAGINGS Specifications for Portable Tanks § 178.255 Specification 60; steel portable tanks. ...

  2. 49 CFR 178.255 - Specification 60; steel portable tanks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Specification 60; steel portable tanks. 178.255 Section 178.255 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND... PACKAGINGS Specifications for Portable Tanks § 178.255 Specification 60; steel portable tanks. ...

  3. 49 CFR 178.255 - Specification 60; steel portable tanks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Specification 60; steel portable tanks. 178.255 Section 178.255 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND... PACKAGINGS Specifications for Portable Tanks § 178.255 Specification 60; steel portable tanks. ...

  4. Inner Speech and Clarity of Self-Concept in Thought Disorder and Auditory-Verbal Hallucinations

    PubMed Central

    de Sousa, Paulo; Sellwood, William; Spray, Amy; Fernyhough, Charles; Bentall, Richard P.

    2016-01-01

    Abstract Eighty patients and thirty controls were interviewed using one interview that promoted personal disclosure and another about everyday topics. Speech was scored using the Thought, Language and Communication scale (TLC). All participants completed the Self-Concept Clarity Scale (SCCS) and the Varieties of Inner Speech Questionnaire (VISQ). Patients scored lower than comparisons on the SCCS. Low scores were associated the disorganized dimension of TD. Patients also scored significantly higher on condensed and other people in inner speech, but not on dialogical or evaluative inner speech. The poverty of speech dimension of TD was associated with less dialogical inner speech, other people in inner speech, and less evaluative inner speech. Hallucinations were significantly associated with more other people in inner speech and evaluative inner speech. Clarity of self-concept and qualities of inner speech are differentially associated with dimensions of TD. The findings also support inner speech models of hallucinations. PMID:27898489

  5. Inner Speech and Clarity of Self-Concept in Thought Disorder and Auditory-Verbal Hallucinations.

    PubMed

    de Sousa, Paulo; Sellwood, William; Spray, Amy; Fernyhough, Charles; Bentall, Richard P

    2016-12-01

    Eighty patients and thirty controls were interviewed using one interview that promoted personal disclosure and another about everyday topics. Speech was scored using the Thought, Language and Communication scale (TLC). All participants completed the Self-Concept Clarity Scale (SCCS) and the Varieties of Inner Speech Questionnaire (VISQ). Patients scored lower than comparisons on the SCCS. Low scores were associated the disorganized dimension of TD. Patients also scored significantly higher on condensed and other people in inner speech, but not on dialogical or evaluative inner speech. The poverty of speech dimension of TD was associated with less dialogical inner speech, other people in inner speech, and less evaluative inner speech. Hallucinations were significantly associated with more other people in inner speech and evaluative inner speech. Clarity of self-concept and qualities of inner speech are differentially associated with dimensions of TD. The findings also support inner speech models of hallucinations.

  6. Perception of synthetic speech produced automatically by rule: Intelligibility of eight text-to-speech systems.

    PubMed

    Greene, Beth G; Logan, John S; Pisoni, David B

    1986-03-01

    We present the results of studies designed to measure the segmental intelligibility of eight text-to-speech systems and a natural speech control, using the Modified Rhyme Test (MRT). Results indicated that the voices tested could be grouped into four categories: natural speech, high-quality synthetic speech, moderate-quality synthetic speech, and low-quality synthetic speech. The overall performance of the best synthesis system, DECtalk-Paul, was equivalent to natural speech only in terms of performance on initial consonants. The findings are discussed in terms of recent work investigating the perception of synthetic speech under more severe conditions. Suggestions for future research on improving the quality of synthetic speech are also considered.

  7. 76 FR 31798 - Airworthiness Directives; L'Hotellier Portable Halon 1211 Fire Extinguishers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ... Airworthiness Directives; L'Hotellier Portable Halon 1211 Fire Extinguishers AGENCY: Federal Aviation... directive (AD) for the specified fire extinguishers. This action requires replacing each unairworthy portable fire extinguisher with an airworthy portable fire extinguisher. This amendment is prompted by an...

  8. 77 FR 58576 - Certain Wireless Communication Devices, Portable Music and Data Processing Devices, Computers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-21

    ... Devices, Portable Music and Data Processing Devices, Computers, and Components Thereof; Institution of... communication devices, portable music and data processing devices, computers, and components thereof by reason... certain wireless communication devices, portable music and data processing devices, computers, and...

  9. 78 FR 34669 - Certain Electronic Devices, Including Wireless Communication Devices, Portable Music and Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ..., Including Wireless Communication Devices, Portable Music and Data Processing Devices, and Tablet Computers... importing wireless communication devices, portable music and data processing devices, and tablet computers... certain electronic devices, including wireless communication devices, portable music and data processing...

  10. 49 CFR 178.255 - Specification 60; steel portable tanks.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Specification 60; steel portable tanks. 178.255 Section 178.255 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... FOR PACKAGINGS Specifications for Portable Tanks § 178.255 Specification 60; steel portable tanks. ...

  11. Peaceful Uses of Nuclear Energy: A Collection of Speeches

    DOE R&D Accomplishments Database

    Seaborg, Glenn T.

    1970-07-01

    It is now a quarter of a century since nuclear energy was introduced to the public. Its introduction was made in the most dramatic, but unfortunately in the most destructive way - through the use of a nuclear weapon. Since that introduction enormous strides have been made in developing the peaceful applications of this great and versatile force. Because these strides have always been overshadowed by the focusing of public attention on the military side of the atom, the public has never fully understood or appreciated the gains and status of the peaceful atom. This booklet is an attempt to correct, in some measure, this imbalance in public information and attitude. It is a compilation of remarks, and excerpts of remarks, that I [Seaborg] have made in recent years in an effort to bring to the public the story of the remarkable benefits the peaceful atom has to offer man. This is a story that grows with the development and progress of the peaceful atom. It must be told so that we can learn to use the power of nuclear energy wisely and through this use help to build a world in which the military applications of the atom will never again be a threat to mankind.

  12. Neural pathways for visual speech perception

    PubMed Central

    Bernstein, Lynne E.; Liebenthal, Einat

    2014-01-01

    This paper examines the questions, what levels of speech can be perceived visually, and how is visual speech represented by the brain? Review of the literature leads to the conclusions that every level of psycholinguistic speech structure (i.e., phonetic features, phonemes, syllables, words, and prosody) can be perceived visually, although individuals differ in their abilities to do so; and that there are visual modality-specific representations of speech qua speech in higher-level vision brain areas. That is, the visual system represents the modal patterns of visual speech. The suggestion that the auditory speech pathway receives and represents visual speech is examined in light of neuroimaging evidence on the auditory speech pathways. We outline the generally agreed-upon organization of the visual ventral and dorsal pathways and examine several types of visual processing that might be related to speech through those pathways, specifically, face and body, orthography, and sign language processing. In this context, we examine the visual speech processing literature, which reveals widespread diverse patterns of activity in posterior temporal cortices in response to visual speech stimuli. We outline a model of the visual and auditory speech pathways and make several suggestions: (1) The visual perception of speech relies on visual pathway representations of speech qua speech. (2) A proposed site of these representations, the temporal visual speech area (TVSA) has been demonstrated in posterior temporal cortex, ventral and posterior to multisensory posterior superior temporal sulcus (pSTS). (3) Given that visual speech has dynamic and configural features, its representations in feedforward visual pathways are expected to integrate these features, possibly in TVSA. PMID:25520611

  13. The Hypothesis of Apraxia of Speech in Children with Autism Spectrum Disorder

    PubMed Central

    Shriberg, Lawrence D.; Paul, Rhea; Black, Lois M.; van Santen, Jan P.

    2010-01-01

    In a sample of 46 children aged 4 to 7 years with Autism Spectrum Disorder (ASD) and intelligible speech, there was no statistical support for the hypothesis of concomitant Childhood Apraxia of Speech (CAS). Perceptual and acoustic measures of participants’ speech, prosody, and voice were compared with data from 40 typically-developing children, 13 preschool children with Speech Delay, and 15 participants aged 5 to 49 years with CAS in neurogenetic disorders. Speech Delay and Speech Errors, respectively, were modestly and substantially more prevalent in participants with ASD than reported population estimates. Double dissociations in speech, prosody, and voice impairments in ASD were interpreted as consistent with a speech attunement framework, rather than with the motor speech impairments that define CAS. Key Words: apraxia, dyspraxia, motor speech disorder, speech sound disorder PMID:20972615

  14. New conceptual design of portable bamboo bridge for emergency purposes

    NASA Astrophysics Data System (ADS)

    Musthaffa, A. A.; Nor, N. M.; Yusof, M. A.; Yuhazri, M. Y.

    2018-02-01

    Portable bridges serve as routes for troops during the military operations and the disaster relief operation. Nowadays, bamboo has been regarded as one of the alternative construction materials for building and bridge structures. This paper presents the conceptual design of the portable bridge. Several types of portable bridges and bamboo bridges are reviewed in the current work. The characteristics, capability and method of construction of each bridge are discussed. Finally, the conceptual of the portable bamboo bridge for emergency purposes is presented. The idea of producing portable bridge is proposed in the current work as it is crucial for providing route for communities affected by natural disasters.

  15. [Advances of portable electrocardiogram monitor design].

    PubMed

    Ding, Shenping; Wang, Yinghai; Wu, Weirong; Deng, Lingli; Lu, Jidong

    2014-06-01

    Portable electrocardiogram monitor is an important equipment in the clinical diagnosis of cardiovascular diseases due to its portable, real-time features. It has a broad application and development prospects in China. In the present review, previous researches on the portable electrocardiogram monitors have been arranged, analyzed and summarized. According to the characteristics of the electrocardiogram (ECG), this paper discusses the ergonomic design of the portable electrocardiogram monitor, including hardware and software. The circuit components and software modules were parsed from the ECG features and system functions. Finally, the development trend and reference are provided for the portable electrocardiogram monitors and for the subsequent research and product design.

  16. Privacy preservation and information security protection for patients' portable electronic health records.

    PubMed

    Huang, Lu-Chou; Chu, Huei-Chung; Lien, Chung-Yueh; Hsiao, Chia-Hung; Kao, Tsair

    2009-09-01

    As patients face the possibility of copying and keeping their electronic health records (EHRs) through portable storage media, they will encounter new risks to the protection of their private information. In this study, we propose a method to preserve the privacy and security of patients' portable medical records in portable storage media to avoid any inappropriate or unintentional disclosure. Following HIPAA guidelines, the method is designed to protect, recover and verify patient's identifiers in portable EHRs. The results of this study show that our methods are effective in ensuring both information security and privacy preservation for patients through portable storage medium.

  17. Speech entrainment enables patients with Broca’s aphasia to produce fluent speech

    PubMed Central

    Hubbard, H. Isabel; Hudspeth, Sarah Grace; Holland, Audrey L.; Bonilha, Leonardo; Fromm, Davida; Rorden, Chris

    2012-01-01

    A distinguishing feature of Broca’s aphasia is non-fluent halting speech typically involving one to three words per utterance. Yet, despite such profound impairments, some patients can mimic audio-visual speech stimuli enabling them to produce fluent speech in real time. We call this effect ‘speech entrainment’ and reveal its neural mechanism as well as explore its usefulness as a treatment for speech production in Broca’s aphasia. In Experiment 1, 13 patients with Broca’s aphasia were tested in three conditions: (i) speech entrainment with audio-visual feedback where they attempted to mimic a speaker whose mouth was seen on an iPod screen; (ii) speech entrainment with audio-only feedback where patients mimicked heard speech; and (iii) spontaneous speech where patients spoke freely about assigned topics. The patients produced a greater variety of words using audio-visual feedback compared with audio-only feedback and spontaneous speech. No difference was found between audio-only feedback and spontaneous speech. In Experiment 2, 10 of the 13 patients included in Experiment 1 and 20 control subjects underwent functional magnetic resonance imaging to determine the neural mechanism that supports speech entrainment. Group results with patients and controls revealed greater bilateral cortical activation for speech produced during speech entrainment compared with spontaneous speech at the junction of the anterior insula and Brodmann area 47, in Brodmann area 37, and unilaterally in the left middle temporal gyrus and the dorsal portion of Broca’s area. Probabilistic white matter tracts constructed for these regions in the normal subjects revealed a structural network connected via the corpus callosum and ventral fibres through the extreme capsule. Unilateral areas were connected via the arcuate fasciculus. In Experiment 3, all patients included in Experiment 1 participated in a 6-week treatment phase using speech entrainment to improve speech production. Behavioural and functional magnetic resonance imaging data were collected before and after the treatment phase. Patients were able to produce a greater variety of words with and without speech entrainment at 1 and 6 weeks after training. Treatment-related decrease in cortical activation associated with speech entrainment was found in areas of the left posterior-inferior parietal lobe. We conclude that speech entrainment allows patients with Broca’s aphasia to double their speech output compared with spontaneous speech. Neuroimaging results suggest that speech entrainment allows patients to produce fluent speech by providing an external gating mechanism that yokes a ventral language network that encodes conceptual aspects of speech. Preliminary results suggest that training with speech entrainment improves speech production in Broca’s aphasia providing a potential therapeutic method for a disorder that has been shown to be particularly resistant to treatment. PMID:23250889

  18. [Speech fluency developmental profile in Brazilian Portuguese speakers].

    PubMed

    Martins, Vanessa de Oliveira; Andrade, Claudia Regina Furquim de

    2008-01-01

    speech fluency varies from one individual to the next, fluent or stutterer, depending on several factors. Studies that investigate the influence of age on fluency patterns have been identified; however these differences were investigated in isolated age groups. Studies about life span fluency variations were not found. to verify the speech fluency developmental profile. speech samples of 594 fluent participants of both genders, with ages between 2:0 and 99:11 years, speakers of the Brazilian Portuguese language, were analyzed. Participants were grouped as follows: pre-scholars, scholars, early adolescence, late adolescence, adults and elderlies. Speech samples were analyzed according to the Speech Fluency Profile variables and were compared regarding: typology of speech disruptions (typical and less typical), speech rate (words and syllables per minute) and frequency of speech disruptions (percentage of speech discontinuity). although isolated variations were identified, overall there was no significant difference between the age groups for the speech disruption indexes (typical and less typical speech disruptions and percentage of speech discontinuity). Significant differences were observed between the groups when considering speech rate. the development of the neurolinguistic system for speech fluency, in terms of speech disruptions, seems to stabilize itself during the first years of life, presenting no alterations during the life span. Indexes of speech rate present variations in the age groups, indicating patterns of acquisition, development, stabilization and degeneration.

  19. Perception of synthetic speech produced automatically by rule: Intelligibility of eight text-to-speech systems

    PubMed Central

    GREENE, BETH G.; LOGAN, JOHN S.; PISONI, DAVID B.

    2012-01-01

    We present the results of studies designed to measure the segmental intelligibility of eight text-to-speech systems and a natural speech control, using the Modified Rhyme Test (MRT). Results indicated that the voices tested could be grouped into four categories: natural speech, high-quality synthetic speech, moderate-quality synthetic speech, and low-quality synthetic speech. The overall performance of the best synthesis system, DECtalk-Paul, was equivalent to natural speech only in terms of performance on initial consonants. The findings are discussed in terms of recent work investigating the perception of synthetic speech under more severe conditions. Suggestions for future research on improving the quality of synthetic speech are also considered. PMID:23225916

  20. Speech Motor Control in Fluent and Dysfluent Speech Production of an Individual with Apraxia of Speech and Broca's Aphasia

    ERIC Educational Resources Information Center

    van Lieshout, Pascal H. H. M.; Bose, Arpita; Square, Paula A.; Steele, Catriona M.

    2007-01-01

    Apraxia of speech (AOS) is typically described as a motor-speech disorder with clinically well-defined symptoms, but without a clear understanding of the underlying problems in motor control. A number of studies have compared the speech of subjects with AOS to the fluent speech of controls, but only a few have included speech movement data and if…

  1. 76 FR 24051 - In the Matter of Certain Electronic Devices, Including Mobile Phones, Mobile Tablets, Portable...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ..., Including Mobile Phones, Mobile Tablets, Portable Music Players, and Computers, and Components Thereof... certain electronic devices, including mobile phones, mobile tablets, portable music players, and computers... mobile phones, mobile tablets, portable music players, and computers, and components thereof that...

  2. 76 FR 45860 - In the Matter of Certain Electronic Devices, Including Wireless Communication Devices, Portable...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-01

    ..., Including Wireless Communication Devices, Portable Music and Data Processing Devices, and Tablet Computers... electronic devices, including wireless communication devices, portable music and data processing devices, and... electronic devices, including wireless communication devices, portable music and data processing devices, and...

  3. 21 CFR 868.5440 - Portable oxygen generator.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Portable oxygen generator. 868.5440 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5440 Portable oxygen generator. (a) Identification. A portable oxygen generator is a device that is intended to release oxygen for respiratory...

  4. 21 CFR 868.5440 - Portable oxygen generator.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Portable oxygen generator. 868.5440 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5440 Portable oxygen generator. (a) Identification. A portable oxygen generator is a device that is intended to release oxygen for respiratory...

  5. 21 CFR 868.5440 - Portable oxygen generator.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Portable oxygen generator. 868.5440 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5440 Portable oxygen generator. (a) Identification. A portable oxygen generator is a device that is intended to release oxygen for respiratory...

  6. 21 CFR 868.5440 - Portable oxygen generator.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Portable oxygen generator. 868.5440 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5440 Portable oxygen generator. (a) Identification. A portable oxygen generator is a device that is intended to release oxygen for respiratory...

  7. 21 CFR 868.5440 - Portable oxygen generator.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Portable oxygen generator. 868.5440 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5440 Portable oxygen generator. (a) Identification. A portable oxygen generator is a device that is intended to release oxygen for respiratory...

  8. Detection of target phonemes in spontaneous and read speech.

    PubMed

    Mehta, G; Cutler, A

    1988-01-01

    Although spontaneous speech occurs more frequently in most listeners' experience than read speech, laboratory studies of human speech recognition typically use carefully controlled materials read from a script. The phonological and prosodic characteristics of spontaneous and read speech differ considerably, however, which suggests that laboratory results may not generalise to the recognition of spontaneous speech. In the present study listeners were presented with both spontaneous and read speech materials, and their response time to detect word-initial target phonemes was measured. Responses were, overall, equally fast in each speech mode. However, analysis of effects previously reported in phoneme detection studies revealed significant differences between speech modes. In read speech but not in spontaneous speech, later targets were detected more rapidly than targets preceded by short words. In contrast, in spontaneous speech but not in read speech, targets were detected more rapidly in accented than in unaccented words and in strong than in weak syllables. An explanation for this pattern is offered in terms of characteristic prosodic differences between spontaneous and read speech. The results support claims from previous work that listeners pay great attention to prosodic information in the process of recognising speech.

  9. Relative Salience of Speech Rhythm and Speech Rate on Perceived Foreign Accent in a Second Language.

    PubMed

    Polyanskaya, Leona; Ordin, Mikhail; Busa, Maria Grazia

    2017-09-01

    We investigated the independent contribution of speech rate and speech rhythm to perceived foreign accent. To address this issue we used a resynthesis technique that allows neutralizing segmental and tonal idiosyncrasies between identical sentences produced by French learners of English at different proficiency levels and maintaining the idiosyncrasies pertaining to prosodic timing patterns. We created stimuli that (1) preserved the idiosyncrasies in speech rhythm while controlling for the differences in speech rate between the utterances; (2) preserved the idiosyncrasies in speech rate while controlling for the differences in speech rhythm between the utterances; and (3) preserved the idiosyncrasies both in speech rate and speech rhythm. All the stimuli were created in intoned (with imposed intonational contour) and flat (with monotonized, constant F0) conditions. The original and the resynthesized sentences were rated by native speakers of English for degree of foreign accent. We found that both speech rate and speech rhythm influence the degree of perceived foreign accent, but the effect of speech rhythm is larger than that of speech rate. We also found that intonation enhances the perception of fine differences in rhythmic patterns but reduces the perceptual salience of fine differences in speech rate.

  10. Review of Visual Speech Perception by Hearing and Hearing-Impaired People: Clinical Implications

    ERIC Educational Resources Information Center

    Woodhouse, Lynn; Hickson, Louise; Dodd, Barbara

    2009-01-01

    Background: Speech perception is often considered specific to the auditory modality, despite convincing evidence that speech processing is bimodal. The theoretical and clinical roles of speech-reading for speech perception, however, have received little attention in speech-language therapy. Aims: The role of speech-read information for speech…

  11. Electrophysiological Evidence for a Multisensory Speech-Specific Mode of Perception

    ERIC Educational Resources Information Center

    Stekelenburg, Jeroen J.; Vroomen, Jean

    2012-01-01

    We investigated whether the interpretation of auditory stimuli as speech or non-speech affects audiovisual (AV) speech integration at the neural level. Perceptually ambiguous sine-wave replicas (SWS) of natural speech were presented to listeners who were either in "speech mode" or "non-speech mode". At the behavioral level, incongruent lipread…

  12. Free Speech Yearbook: 1972.

    ERIC Educational Resources Information Center

    Tedford, Thomas L., Ed.

    This book is a collection of essays on free speech issues and attitudes, compiled by the Commission on Freedom of Speech of the Speech Communication Association. Four articles focus on freedom of speech in classroom situations as follows: a philosophic view of teaching free speech, effects of a course on free speech on student attitudes,…

  13. The Neural Bases of Difficult Speech Comprehension and Speech Production: Two Activation Likelihood Estimation (ALE) Meta-Analyses

    ERIC Educational Resources Information Center

    Adank, Patti

    2012-01-01

    The role of speech production mechanisms in difficult speech comprehension is the subject of on-going debate in speech science. Two Activation Likelihood Estimation (ALE) analyses were conducted on neuroimaging studies investigating difficult speech comprehension or speech production. Meta-analysis 1 included 10 studies contrasting comprehension…

  14. Methods and apparatus for non-acoustic speech characterization and recognition

    DOEpatents

    Holzrichter, John F.

    1999-01-01

    By simultaneously recording EM wave reflections and acoustic speech information, the positions and velocities of the speech organs as speech is articulated can be defined for each acoustic speech unit. Well defined time frames and feature vectors describing the speech, to the degree required, can be formed. Such feature vectors can uniquely characterize the speech unit being articulated each time frame. The onset of speech, rejection of external noise, vocalized pitch periods, articulator conditions, accurate timing, the identification of the speaker, acoustic speech unit recognition, and organ mechanical parameters can be determined.

  15. Methods and apparatus for non-acoustic speech characterization and recognition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holzrichter, J.F.

    By simultaneously recording EM wave reflections and acoustic speech information, the positions and velocities of the speech organs as speech is articulated can be defined for each acoustic speech unit. Well defined time frames and feature vectors describing the speech, to the degree required, can be formed. Such feature vectors can uniquely characterize the speech unit being articulated each time frame. The onset of speech, rejection of external noise, vocalized pitch periods, articulator conditions, accurate timing, the identification of the speaker, acoustic speech unit recognition, and organ mechanical parameters can be determined.

  16. Voice technology and BBN

    NASA Technical Reports Server (NTRS)

    Wolf, Jared J.

    1977-01-01

    The following research was discussed: (1) speech signal processing; (2) automatic speech recognition; (3) continuous speech understanding; (4) speaker recognition; (5) speech compression; (6) subjective and objective evaluation of speech communication system; (7) measurement of the intelligibility and quality of speech when degraded by noise or other masking stimuli; (8) speech synthesis; (9) instructional aids for second-language learning and for training of the deaf; and (10) investigation of speech correlates of psychological stress. Experimental psychology, control systems, and human factors engineering, which are often relevant to the proper design and operation of speech systems are described.

  17. A functional speech impression used to fabricate a maxillary speech prosthesis for a partial glossectomy patient.

    PubMed

    Knowles, J C; Chalian, V A; Shanks, J C

    1984-02-01

    Surgery for cancer of the floor of the mouth often results in alteration of the muscles of the tongue and floor of the mouth. Both primary and secondary surgical procedures often result in scar formation with reduced mobility of the tongue during speech and deglutition. Speech is often used as a diagnostic tool in the placement of the anterior teeth during fabrication of a prosthesis. Speech can similarly be used to help determine the proper placement of a speech portion of the prosthesis. The prosthetic rehabilitation approach described lowers the palatal vault with a false palate to enable the tongue to function against it during speech (Fig. 15). Group studies have shown that the design and fabrication of speech prostheses for partial glossectomy patients have significantly improved speech and swallowing for these patients. A speech pathologist is helpful during diagnosis, and speech therapy is necessary for significant speech improvement. Prosthetic rehabilitation alone cannot be expected to improve speech.

  18. Speech Rhythms and Multiplexed Oscillatory Sensory Coding in the Human Brain

    PubMed Central

    Gross, Joachim; Hoogenboom, Nienke; Thut, Gregor; Schyns, Philippe; Panzeri, Stefano; Belin, Pascal; Garrod, Simon

    2013-01-01

    Cortical oscillations are likely candidates for segmentation and coding of continuous speech. Here, we monitored continuous speech processing with magnetoencephalography (MEG) to unravel the principles of speech segmentation and coding. We demonstrate that speech entrains the phase of low-frequency (delta, theta) and the amplitude of high-frequency (gamma) oscillations in the auditory cortex. Phase entrainment is stronger in the right and amplitude entrainment is stronger in the left auditory cortex. Furthermore, edges in the speech envelope phase reset auditory cortex oscillations thereby enhancing their entrainment to speech. This mechanism adapts to the changing physical features of the speech envelope and enables efficient, stimulus-specific speech sampling. Finally, we show that within the auditory cortex, coupling between delta, theta, and gamma oscillations increases following speech edges. Importantly, all couplings (i.e., brain-speech and also within the cortex) attenuate for backward-presented speech, suggesting top-down control. We conclude that segmentation and coding of speech relies on a nested hierarchy of entrained cortical oscillations. PMID:24391472

  19. Specific acoustic models for spontaneous and dictated style in indonesian speech recognition

    NASA Astrophysics Data System (ADS)

    Vista, C. B.; Satriawan, C. H.; Lestari, D. P.; Widyantoro, D. H.

    2018-03-01

    The performance of an automatic speech recognition system is affected by differences in speech style between the data the model is originally trained upon and incoming speech to be recognized. In this paper, the usage of GMM-HMM acoustic models for specific speech styles is investigated. We develop two systems for the experiments; the first employs a speech style classifier to predict the speech style of incoming speech, either spontaneous or dictated, then decodes this speech using an acoustic model specifically trained for that speech style. The second system uses both acoustic models to recognise incoming speech and decides upon a final result by calculating a confidence score of decoding. Results show that training specific acoustic models for spontaneous and dictated speech styles confers a slight recognition advantage as compared to a baseline model trained on a mixture of spontaneous and dictated training data. In addition, the speech style classifier approach of the first system produced slightly more accurate results than the confidence scoring employed in the second system.

  20. Severity-Based Adaptation with Limited Data for ASR to Aid Dysarthric Speakers

    PubMed Central

    Mustafa, Mumtaz Begum; Salim, Siti Salwah; Mohamed, Noraini; Al-Qatab, Bassam; Siong, Chng Eng

    2014-01-01

    Automatic speech recognition (ASR) is currently used in many assistive technologies, such as helping individuals with speech impairment in their communication ability. One challenge in ASR for speech-impaired individuals is the difficulty in obtaining a good speech database of impaired speakers for building an effective speech acoustic model. Because there are very few existing databases of impaired speech, which are also limited in size, the obvious solution to build a speech acoustic model of impaired speech is by employing adaptation techniques. However, issues that have not been addressed in existing studies in the area of adaptation for speech impairment are as follows: (1) identifying the most effective adaptation technique for impaired speech; and (2) the use of suitable source models to build an effective impaired-speech acoustic model. This research investigates the above-mentioned two issues on dysarthria, a type of speech impairment affecting millions of people. We applied both unimpaired and impaired speech as the source model with well-known adaptation techniques like the maximum likelihood linear regression (MLLR) and the constrained-MLLR(C-MLLR). The recognition accuracy of each impaired speech acoustic model is measured in terms of word error rate (WER), with further assessments, including phoneme insertion, substitution and deletion rates. Unimpaired speech when combined with limited high-quality speech-impaired data improves performance of ASR systems in recognising severely impaired dysarthric speech. The C-MLLR adaptation technique was also found to be better than MLLR in recognising mildly and moderately impaired speech based on the statistical analysis of the WER. It was found that phoneme substitution was the biggest contributing factor in WER in dysarthric speech for all levels of severity. The results show that the speech acoustic models derived from suitable adaptation techniques improve the performance of ASR systems in recognising impaired speech with limited adaptation data. PMID:24466004

  1. 29 CFR 1910.25 - Portable wood ladders.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 5 2013-07-01 2013-07-01 false Portable wood ladders. 1910.25 Section 1910.25 Labor... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Walking-Working Surfaces § 1910.25 Portable wood ladders. (a... for the construction, care, and use of the common types of portable wood ladders, in order to insure...

  2. 29 CFR 1910.25 - Portable wood ladders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 5 2014-07-01 2014-07-01 false Portable wood ladders. 1910.25 Section 1910.25 Labor... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Walking-Working Surfaces § 1910.25 Portable wood ladders. (a... for the construction, care, and use of the common types of portable wood ladders, in order to insure...

  3. 46 CFR 98.33-5 - Portable tanks authorized.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Portable tanks authorized. 98.33-5 Section 98.33-5... CONSTRUCTION, ARRANGEMENT, AND OTHER PROVISIONS FOR CERTAIN DANGEROUS CARGOES IN BULK Portable Tanks for Certain Grade E Combustible Liquids and Other Regulated Materials § 98.33-5 Portable tanks authorized. The...

  4. 46 CFR 98.33-5 - Portable tanks authorized.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Portable tanks authorized. 98.33-5 Section 98.33-5... CONSTRUCTION, ARRANGEMENT, AND OTHER PROVISIONS FOR CERTAIN DANGEROUS CARGOES IN BULK Portable Tanks for Certain Grade E Combustible Liquids and Other Regulated Materials § 98.33-5 Portable tanks authorized. The...

  5. 49 CFR 172.326 - Portable tanks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 2 2012-10-01 2012-10-01 false Portable tanks. 172.326 Section 172.326... SECURITY PLANS Marking § 172.326 Portable tanks. (a) Shipping name. No person may offer for transportation or transport a portable tank containing a hazardous material unless it is legibly marked on two...

  6. 49 CFR 172.326 - Portable tanks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Portable tanks. 172.326 Section 172.326... SECURITY PLANS Marking § 172.326 Portable tanks. (a) Shipping name. No person may offer for transportation or transport a portable tank containing a hazardous material unless it is legibly marked on two...

  7. 49 CFR 172.326 - Portable tanks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false Portable tanks. 172.326 Section 172.326... SECURITY PLANS Marking § 172.326 Portable tanks. (a) Shipping name. No person may offer for transportation or transport a portable tank containing a hazardous material unless it is legibly marked on two...

  8. 49 CFR 172.326 - Portable tanks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false Portable tanks. 172.326 Section 172.326... SECURITY PLANS Marking § 172.326 Portable tanks. (a) Shipping name. No person may offer for transportation or transport a portable tank containing a hazardous material unless it is legibly marked on two...

  9. 78 FR 33393 - Petition Requesting a Ban or Standard on Adult Portable Bed Rails

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... Standard on Adult Portable Bed Rails AGENCY: Consumer Product Safety Commission. ACTION: Notice. SUMMARY... adult portable bed rails pose an unreasonable risk of injury and initiate related rulemaking under... that adult portable bed rails pose an unreasonable risk of injury and initiate related rulemaking under...

  10. 21 CFR 868.6250 - Portable air compressor.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Portable air compressor. 868.6250 Section 868.6250...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Miscellaneous § 868.6250 Portable air compressor. (a) Identification. A portable air compressor is a device intended to provide compressed air for medical purposes, e...

  11. 47 CFR 73.1530 - Portable test stations [Definition].

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Portable test stations [Definition]. 73.1530 Section 73.1530 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.1530 Portable test stations [Definition]. A portable test station is one...

  12. 47 CFR 73.1530 - Portable test stations [Definition].

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Portable test stations [Definition]. 73.1530 Section 73.1530 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.1530 Portable test stations [Definition]. A portable test station is one...

  13. 30 CFR 47.44 - Temporary, portable containers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Temporary, portable containers. 47.44 Section... TRAINING HAZARD COMMUNICATION (HazCom) Container Labels and Other Forms of Warning § 47.44 Temporary, portable containers. (a) The operator does not have to label a temporary, portable container if he or she...

  14. 21 CFR 868.6250 - Portable air compressor.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Portable air compressor. 868.6250 Section 868.6250...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Miscellaneous § 868.6250 Portable air compressor. (a) Identification. A portable air compressor is a device intended to provide compressed air for medical purposes, e...

  15. 21 CFR 868.6250 - Portable air compressor.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Portable air compressor. 868.6250 Section 868.6250...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Miscellaneous § 868.6250 Portable air compressor. (a) Identification. A portable air compressor is a device intended to provide compressed air for medical purposes, e...

  16. 47 CFR 52.33 - Recovery of carrier-specific costs directly related to providing long-term number portability.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Recovery of carrier-specific costs directly related to providing long-term number portability. (a... related to providing long-term number portability. 52.33 Section 52.33 Telecommunication FEDERAL... long-term number portability by establishing in tariffs filed with the Federal Communications...

  17. 47 CFR 52.33 - Recovery of carrier-specific costs directly related to providing long-term number portability.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Recovery of carrier-specific costs directly related to providing long-term number portability. (a... related to providing long-term number portability. 52.33 Section 52.33 Telecommunication FEDERAL... long-term number portability by establishing in tariffs filed with the Federal Communications...

  18. 47 CFR 52.33 - Recovery of carrier-specific costs directly related to providing long-term number portability.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Recovery of carrier-specific costs directly related to providing long-term number portability. (a... related to providing long-term number portability. 52.33 Section 52.33 Telecommunication FEDERAL... long-term number portability by establishing in tariffs filed with the Federal Communications...

  19. 47 CFR 52.33 - Recovery of carrier-specific costs directly related to providing long-term number portability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Recovery of carrier-specific costs directly related to providing long-term number portability. (a... related to providing long-term number portability. 52.33 Section 52.33 Telecommunication FEDERAL... long-term number portability by establishing in tariffs filed with the Federal Communications...

  20. 29 CFR 1915.132 - Portable electric tools.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Portable electric tools. 1915.132 Section 1915.132 Labor... § 1915.132 Portable electric tools. The provisions of this section shall apply to ship repairing... frames of portable electric tools and appliances, except double insulated tools approved by Underwriters...

  1. 29 CFR 1915.132 - Portable electric tools.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Portable electric tools. 1915.132 Section 1915.132 Labor... § 1915.132 Portable electric tools. The provisions of this section shall apply to ship repairing... frames of portable electric tools and appliances, except double insulated tools approved by Underwriters...

  2. 29 CFR 1915.132 - Portable electric tools.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Portable electric tools. 1915.132 Section 1915.132 Labor... § 1915.132 Portable electric tools. The provisions of this section shall apply to ship repairing... frames of portable electric tools and appliances, except double insulated tools approved by Underwriters...

  3. 29 CFR 1915.132 - Portable electric tools.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Portable electric tools. 1915.132 Section 1915.132 Labor... § 1915.132 Portable electric tools. The provisions of this section shall apply to ship repairing... frames of portable electric tools and appliances, except double insulated tools approved by Underwriters...

  4. 29 CFR 1915.132 - Portable electric tools.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Portable electric tools. 1915.132 Section 1915.132 Labor... § 1915.132 Portable electric tools. The provisions of this section shall apply to ship repairing... frames of portable electric tools and appliances, except double insulated tools approved by Underwriters...

  5. 47 CFR 80.53 - Application for a portable ship station license.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Application for a portable ship station license... a portable ship station license. The Commission may grant a license permitting operation of a portable ship station aboard different vessels of the United States. [63 FR 68956, Dec. 14, 1998] ...

  6. 47 CFR 80.53 - Application for a portable ship station license.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Application for a portable ship station license... a portable ship station license. The Commission may grant a license permitting operation of a portable ship station aboard different vessels of the United States. [63 FR 68956, Dec. 14, 1998] ...

  7. 47 CFR 80.53 - Application for a portable ship station license.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Application for a portable ship station license... a portable ship station license. The Commission may grant a license permitting operation of a portable ship station aboard different vessels of the United States. [63 FR 68956, Dec. 14, 1998] ...

  8. 47 CFR 80.53 - Application for a portable ship station license.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Application for a portable ship station license... a portable ship station license. The Commission may grant a license permitting operation of a portable ship station aboard different vessels of the United States. [63 FR 68956, Dec. 14, 1998] ...

  9. 47 CFR 80.53 - Application for a portable ship station license.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Application for a portable ship station license... a portable ship station license. The Commission may grant a license permitting operation of a portable ship station aboard different vessels of the United States. [63 FR 68956, Dec. 14, 1998] ...

  10. Enabling Logistics With Portable and Wireless Technology Study. Volume 1

    DTIC Science & Technology

    2004-08-06

    Project”, Ubiquitous Computing Group Microsoft Research, 2001. 102 Enabling Logistics with Portable and Wireless Technology Study ...Enabling Logistics with Portable and Wireless Technology Study Final Report FINAL REPORT...Volume I) Enabling Logistics with Portable and Wireless Technology Study AUTHORS School of Industrial Engineering Dr. Soundar Kumara

  11. 14 CFR 135.144 - Portable electronic devices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Portable electronic devices. 135.144... Equipment § 135.144 Portable electronic devices. (a) Except as provided in paragraph (b) of this section, no... portable electronic device on any of the following U.S.-registered civil aircraft operating under this part...

  12. 14 CFR 135.144 - Portable electronic devices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Portable electronic devices. 135.144... Equipment § 135.144 Portable electronic devices. (a) Except as provided in paragraph (b) of this section, no... portable electronic device on any of the following U.S.-registered civil aircraft operating under this part...

  13. 14 CFR 125.204 - Portable electronic devices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Portable electronic devices. 125.204... Equipment Requirements § 125.204 Portable electronic devices. (a) Except as provided in paragraph (b) of... operation of, any portable electronic device on any U.S.-registered civil aircraft operating under this part...

  14. 14 CFR 125.204 - Portable electronic devices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Portable electronic devices. 125.204... Equipment Requirements § 125.204 Portable electronic devices. (a) Except as provided in paragraph (b) of... operation of, any portable electronic device on any U.S.-registered civil aircraft operating under this part...

  15. 14 CFR 125.204 - Portable electronic devices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Portable electronic devices. 125.204... Equipment Requirements § 125.204 Portable electronic devices. (a) Except as provided in paragraph (b) of... operation of, any portable electronic device on any U.S.-registered civil aircraft operating under this part...

  16. 14 CFR 125.204 - Portable electronic devices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Portable electronic devices. 125.204... Equipment Requirements § 125.204 Portable electronic devices. (a) Except as provided in paragraph (b) of... operation of, any portable electronic device on any U.S.-registered civil aircraft operating under this part...

  17. 14 CFR 135.144 - Portable electronic devices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Portable electronic devices. 135.144... Equipment § 135.144 Portable electronic devices. (a) Except as provided in paragraph (b) of this section, no... portable electronic device on any of the following U.S.-registered civil aircraft operating under this part...

  18. 14 CFR 135.144 - Portable electronic devices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Portable electronic devices. 135.144... Equipment § 135.144 Portable electronic devices. (a) Except as provided in paragraph (b) of this section, no... portable electronic device on any of the following U.S.-registered civil aircraft operating under this part...

  19. 14 CFR 125.204 - Portable electronic devices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Portable electronic devices. 125.204... Equipment Requirements § 125.204 Portable electronic devices. (a) Except as provided in paragraph (b) of... operation of, any portable electronic device on any U.S.-registered civil aircraft operating under this part...

  20. 14 CFR 135.144 - Portable electronic devices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Portable electronic devices. 135.144... Equipment § 135.144 Portable electronic devices. (a) Except as provided in paragraph (b) of this section, no... portable electronic device on any of the following U.S.-registered civil aircraft operating under this part...

  1. 47 CFR 15.703 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... channels on which the Mode I device, but not the fixed device, may operate. (d) Geo-location capability.../portable device. A personal/portable TVBD that does not use an internal geo-location capability and access.../portable device. A personal/portable TVBD that uses an internal geo-location capability and access to a TV...

  2. 33 CFR 127.203 - Portable gas detectors.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Portable gas detectors. 127.203... Waterfront Facilities Handling Liquefied Natural Gas Equipment § 127.203 Portable gas detectors. The marine transfer area for LNG must have at least two portable gas detectors capable of measuring 0-100% of the...

  3. 33 CFR 127.203 - Portable gas detectors.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Portable gas detectors. 127.203... Waterfront Facilities Handling Liquefied Natural Gas Equipment § 127.203 Portable gas detectors. The marine transfer area for LNG must have at least two portable gas detectors capable of measuring 0-100% of the...

  4. 33 CFR 127.203 - Portable gas detectors.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Portable gas detectors. 127.203... Waterfront Facilities Handling Liquefied Natural Gas Equipment § 127.203 Portable gas detectors. The marine transfer area for LNG must have at least two portable gas detectors capable of measuring 0-100% of the...

  5. 33 CFR 127.203 - Portable gas detectors.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Portable gas detectors. 127.203... Waterfront Facilities Handling Liquefied Natural Gas Equipment § 127.203 Portable gas detectors. The marine transfer area for LNG must have at least two portable gas detectors capable of measuring 0-100% of the...

  6. 33 CFR 127.203 - Portable gas detectors.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Portable gas detectors. 127.203... Waterfront Facilities Handling Liquefied Natural Gas Equipment § 127.203 Portable gas detectors. The marine transfer area for LNG must have at least two portable gas detectors capable of measuring 0-100% of the...

  7. 48 CFR 1852.237-71 - Pension portability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Pension portability. 1852... 1852.237-71 Pension portability. As prescribed at 1837.110-70(b), insert the following clause: Pension Portability (JAN 1997) (a) In order for pension costs attributable to employees assigned to this contract to...

  8. 46 CFR 183.430 - Portable lights

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Portable lights 183.430 Section 183.430 Shipping COAST...) ELECTRICAL INSTALLATION Lighting Systems § 183.430 Portable lights Each vessel must be equipped with at least two operable portable battery lights. One of these lights must be located at the operating station and...

  9. 46 CFR 183.430 - Portable lights

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Portable lights 183.430 Section 183.430 Shipping COAST...) ELECTRICAL INSTALLATION Lighting Systems § 183.430 Portable lights Each vessel must be equipped with at least two operable portable battery lights. One of these lights must be located at the operating station and...

  10. 46 CFR 183.430 - Portable lights

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Portable lights 183.430 Section 183.430 Shipping COAST...) ELECTRICAL INSTALLATION Lighting Systems § 183.430 Portable lights Each vessel must be equipped with at least two operable portable battery lights. One of these lights must be located at the operating station and...

  11. 46 CFR 183.430 - Portable lights

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Portable lights 183.430 Section 183.430 Shipping COAST...) ELECTRICAL INSTALLATION Lighting Systems § 183.430 Portable lights Each vessel must be equipped with at least two operable portable battery lights. One of these lights must be located at the operating station and...

  12. 46 CFR 183.430 - Portable lights

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Portable lights 183.430 Section 183.430 Shipping COAST...) ELECTRICAL INSTALLATION Lighting Systems § 183.430 Portable lights Each vessel must be equipped with at least two operable portable battery lights. One of these lights must be located at the operating station and...

  13. Speech outcomes in Cantonese patients after glossectomy.

    PubMed

    Wong, Ripley Kit; Poon, Esther Sok-Man; Woo, Cynthia Yuen-Man; Chan, Sabina Ching-Shun; Wong, Elsa Siu-Ping; Chu, Ada Wai-Sze

    2007-08-01

    We sought to determine the major factors affecting speech production of Cantonese-speaking glossectomized patients. Error pattern was analyzed. Forty-one Cantonese-speaking subjects who had undergone glossectomy > or = 6 months previously were recruited. Speech production evaluation included (1) phonetic error analysis in nonsense syllable; (2) speech intelligibility in sentences evaluated by naive listeners; (3) overall speech intelligibility in conversation evaluated by experienced speech therapists. Patients receiving adjuvant radiotherapy had significantly poorer segmental and connected speech production. Total or subtotal glossectomy also resulted in poor speech outcomes. Patients having free flap reconstruction showed the best speech outcomes. Patients without lymph node metastasis had significantly better speech scores when compared with patients with lymph node metastasis. Initial consonant production had the worst scores, while vowel production was the least affected. Speech outcomes of Cantonese-speaking glossectomized patients depended on the severity of the disease. Initial consonants had the greatest effect on speech intelligibility.

  14. Can you hear my age? Influences of speech rate and speech spontaneity on estimation of speaker age

    PubMed Central

    Skoog Waller, Sara; Eriksson, Mårten; Sörqvist, Patrik

    2015-01-01

    Cognitive hearing science is mainly about the study of how cognitive factors contribute to speech comprehension, but cognitive factors also partake in speech processing to infer non-linguistic information from speech signals, such as the intentions of the talker and the speaker’s age. Here, we report two experiments on age estimation by “naïve” listeners. The aim was to study how speech rate influences estimation of speaker age by comparing the speakers’ natural speech rate with increased or decreased speech rate. In Experiment 1, listeners were presented with audio samples of read speech from three different speaker age groups (young, middle aged, and old adults). They estimated the speakers as younger when speech rate was faster than normal and as older when speech rate was slower than normal. This speech rate effect was slightly greater in magnitude for older (60–65 years) speakers in comparison with younger (20–25 years) speakers, suggesting that speech rate may gain greater importance as a perceptual age cue with increased speaker age. This pattern was more pronounced in Experiment 2, in which listeners estimated age from spontaneous speech. Faster speech rate was associated with lower age estimates, but only for older and middle aged (40–45 years) speakers. Taken together, speakers of all age groups were estimated as older when speech rate decreased, except for the youngest speakers in Experiment 2. The absence of a linear speech rate effect in estimates of younger speakers, for spontaneous speech, implies that listeners use different age estimation strategies or cues (possibly vocabulary) depending on the age of the speaker and the spontaneity of the speech. Potential implications for forensic investigations and other applied domains are discussed. PMID:26236259

  15. Emotionally conditioning the target-speech voice enhances recognition of the target speech under "cocktail-party" listening conditions.

    PubMed

    Lu, Lingxi; Bao, Xiaohan; Chen, Jing; Qu, Tianshu; Wu, Xihong; Li, Liang

    2018-05-01

    Under a noisy "cocktail-party" listening condition with multiple people talking, listeners can use various perceptual/cognitive unmasking cues to improve recognition of the target speech against informational speech-on-speech masking. One potential unmasking cue is the emotion expressed in a speech voice, by means of certain acoustical features. However, it was unclear whether emotionally conditioning a target-speech voice that has none of the typical acoustical features of emotions (i.e., an emotionally neutral voice) can be used by listeners for enhancing target-speech recognition under speech-on-speech masking conditions. In this study we examined the recognition of target speech against a two-talker speech masker both before and after the emotionally neutral target voice was paired with a loud female screaming sound that has a marked negative emotional valence. The results showed that recognition of the target speech (especially the first keyword in a target sentence) was significantly improved by emotionally conditioning the target speaker's voice. Moreover, the emotional unmasking effect was independent of the unmasking effect of the perceived spatial separation between the target speech and the masker. Also, (skin conductance) electrodermal responses became stronger after emotional learning when the target speech and masker were perceptually co-located, suggesting an increase of listening efforts when the target speech was informationally masked. These results indicate that emotionally conditioning the target speaker's voice does not change the acoustical parameters of the target-speech stimuli, but the emotionally conditioned vocal features can be used as cues for unmasking target speech.

  16. Giving speech a hand: gesture modulates activity in auditory cortex during speech perception.

    PubMed

    Hubbard, Amy L; Wilson, Stephen M; Callan, Daniel E; Dapretto, Mirella

    2009-03-01

    Viewing hand gestures during face-to-face communication affects speech perception and comprehension. Despite the visible role played by gesture in social interactions, relatively little is known about how the brain integrates hand gestures with co-occurring speech. Here we used functional magnetic resonance imaging (fMRI) and an ecologically valid paradigm to investigate how beat gesture-a fundamental type of hand gesture that marks speech prosody-might impact speech perception at the neural level. Subjects underwent fMRI while listening to spontaneously-produced speech accompanied by beat gesture, nonsense hand movement, or a still body; as additional control conditions, subjects also viewed beat gesture, nonsense hand movement, or a still body all presented without speech. Validating behavioral evidence that gesture affects speech perception, bilateral nonprimary auditory cortex showed greater activity when speech was accompanied by beat gesture than when speech was presented alone. Further, the left superior temporal gyrus/sulcus showed stronger activity when speech was accompanied by beat gesture than when speech was accompanied by nonsense hand movement. Finally, the right planum temporale was identified as a putative multisensory integration site for beat gesture and speech (i.e., here activity in response to speech accompanied by beat gesture was greater than the summed responses to speech alone and beat gesture alone), indicating that this area may be pivotally involved in synthesizing the rhythmic aspects of both speech and gesture. Taken together, these findings suggest a common neural substrate for processing speech and gesture, likely reflecting their joint communicative role in social interactions.

  17. Giving Speech a Hand: Gesture Modulates Activity in Auditory Cortex During Speech Perception

    PubMed Central

    Hubbard, Amy L.; Wilson, Stephen M.; Callan, Daniel E.; Dapretto, Mirella

    2008-01-01

    Viewing hand gestures during face-to-face communication affects speech perception and comprehension. Despite the visible role played by gesture in social interactions, relatively little is known about how the brain integrates hand gestures with co-occurring speech. Here we used functional magnetic resonance imaging (fMRI) and an ecologically valid paradigm to investigate how beat gesture – a fundamental type of hand gesture that marks speech prosody – might impact speech perception at the neural level. Subjects underwent fMRI while listening to spontaneously-produced speech accompanied by beat gesture, nonsense hand movement, or a still body; as additional control conditions, subjects also viewed beat gesture, nonsense hand movement, or a still body all presented without speech. Validating behavioral evidence that gesture affects speech perception, bilateral nonprimary auditory cortex showed greater activity when speech was accompanied by beat gesture than when speech was presented alone. Further, the left superior temporal gyrus/sulcus showed stronger activity when speech was accompanied by beat gesture than when speech was accompanied by nonsense hand movement. Finally, the right planum temporale was identified as a putative multisensory integration site for beat gesture and speech (i.e., here activity in response to speech accompanied by beat gesture was greater than the summed responses to speech alone and beat gesture alone), indicating that this area may be pivotally involved in synthesizing the rhythmic aspects of both speech and gesture. Taken together, these findings suggest a common neural substrate for processing speech and gesture, likely reflecting their joint communicative role in social interactions. PMID:18412134

  18. Visual Speech Fills in Both Discrimination and Identification of Non-Intact Auditory Speech in Children

    ERIC Educational Resources Information Center

    Jerger, Susan; Damian, Markus F.; McAlpine, Rachel P.; Abdi, Herve

    2018-01-01

    To communicate, children must discriminate and identify speech sounds. Because visual speech plays an important role in this process, we explored how visual speech influences phoneme discrimination and identification by children. Critical items had intact visual speech (e.g. baez) coupled to non-intact (excised onsets) auditory speech (signified…

  19. Multilevel Analysis in Analyzing Speech Data

    ERIC Educational Resources Information Center

    Guddattu, Vasudeva; Krishna, Y.

    2011-01-01

    The speech produced by human vocal tract is a complex acoustic signal, with diverse applications in phonetics, speech synthesis, automatic speech recognition, speaker identification, communication aids, speech pathology, speech perception, machine translation, hearing research, rehabilitation and assessment of communication disorders and many…

  20. Speech communications in noise

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The physical characteristics of speech, the methods of speech masking measurement, and the effects of noise on speech communication are investigated. Topics include the speech signal and intelligibility, the effects of noise on intelligibility, the articulation index, and various devices for evaluating speech systems.

  1. The influence of visual and auditory information on the perception of speech and non-speech oral movements in patients with left hemisphere lesions.

    PubMed

    Schmid, Gabriele; Thielmann, Anke; Ziegler, Wolfram

    2009-03-01

    Patients with lesions of the left hemisphere often suffer from oral-facial apraxia, apraxia of speech, and aphasia. In these patients, visual features often play a critical role in speech and language therapy, when pictured lip shapes or the therapist's visible mouth movements are used to facilitate speech production and articulation. This demands audiovisual processing both in speech and language treatment and in the diagnosis of oral-facial apraxia. The purpose of this study was to investigate differences in audiovisual perception of speech as compared to non-speech oral gestures. Bimodal and unimodal speech and non-speech items were used and additionally discordant stimuli constructed, which were presented for imitation. This study examined a group of healthy volunteers and a group of patients with lesions of the left hemisphere. Patients made substantially more errors than controls, but the factors influencing imitation accuracy were more or less the same in both groups. Error analyses in both groups suggested different types of representations for speech as compared to the non-speech domain, with speech having a stronger weight on the auditory modality and non-speech processing on the visual modality. Additionally, this study was able to show that the McGurk effect is not limited to speech.

  2. The Levels of Speech Usage Rating Scale: Comparison of Client Self-Ratings with Speech Pathologist Ratings

    ERIC Educational Resources Information Center

    Gray, Christina; Baylor, Carolyn; Eadie, Tanya; Kendall, Diane; Yorkston, Kathryn

    2012-01-01

    Background: The term "speech usage" refers to what people want or need to do with their speech to fulfil the communication demands in their life roles. Speech-language pathologists (SLPs) need to know about clients' speech usage to plan appropriate interventions to meet their life participation goals. The Levels of Speech Usage is a…

  3. Speech Anxiety: The Importance of Identification in the Basic Speech Course.

    ERIC Educational Resources Information Center

    Mandeville, Mary Y.

    A study investigated speech anxiety in the basic speech course by means of pre and post essays. Subjects, 73 students in 3 classes in the basic speech course at a southwestern multiuniversity, wrote a two-page essay on their perceptions of their speech anxiety before the first speaking project. Students discussed speech anxiety in class and were…

  4. Automatic speech recognition (ASR) based approach for speech therapy of aphasic patients: A review

    NASA Astrophysics Data System (ADS)

    Jamal, Norezmi; Shanta, Shahnoor; Mahmud, Farhanahani; Sha'abani, MNAH

    2017-09-01

    This paper reviews the state-of-the-art an automatic speech recognition (ASR) based approach for speech therapy of aphasic patients. Aphasia is a condition in which the affected person suffers from speech and language disorder resulting from a stroke or brain injury. Since there is a growing body of evidence indicating the possibility of improving the symptoms at an early stage, ASR based solutions are increasingly being researched for speech and language therapy. ASR is a technology that transfers human speech into transcript text by matching with the system's library. This is particularly useful in speech rehabilitation therapies as they provide accurate, real-time evaluation for speech input from an individual with speech disorder. ASR based approaches for speech therapy recognize the speech input from the aphasic patient and provide real-time feedback response to their mistakes. However, the accuracy of ASR is dependent on many factors such as, phoneme recognition, speech continuity, speaker and environmental differences as well as our depth of knowledge on human language understanding. Hence, the review examines recent development of ASR technologies and its performance for individuals with speech and language disorders.

  5. 5 CFR 870.1205 - Electing portability for Option B.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Electing portability for Option B. 870... portability for Option B. (a) The employing agency must notify the employee/assignee(s) of the loss of coverage and the right to elect portability for Option B either before or immediately after the event...

  6. 46 CFR 107.235 - Servicing of hand portable fire extinguishers, semi-portable fire extinguishers and fixed fire...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Servicing of hand portable fire extinguishers, semi-portable fire extinguishers and fixed fire extinguishing systems. 107.235 Section 107.235 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND...

  7. 46 CFR 107.235 - Servicing of hand portable fire extinguishers, semi-portable fire extinguishers and fixed fire...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Servicing of hand portable fire extinguishers, semi-portable fire extinguishers and fixed fire-extinguishing systems. 107.235 Section 107.235 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND...

  8. 46 CFR 107.235 - Servicing of hand portable fire extinguishers, semi-portable fire extinguishers and fixed fire...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Servicing of hand portable fire extinguishers, semi-portable fire extinguishers and fixed fire-extinguishing systems. 107.235 Section 107.235 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND...

  9. 46 CFR 107.235 - Servicing of hand portable fire extinguishers, semi-portable fire extinguishers and fixed fire...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Servicing of hand portable fire extinguishers, semi-portable fire extinguishers and fixed fire extinguishing systems. 107.235 Section 107.235 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND...

  10. 46 CFR 107.235 - Servicing of hand portable fire extinguishers, semi-portable fire extinguishers and fixed fire...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Servicing of hand portable fire extinguishers, semi-portable fire extinguishers and fixed fire extinguishing systems. 107.235 Section 107.235 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND...

  11. Engineering Resilience Into The Marine Expeditionary Units Resupply System Through Military Foraging

    DTIC Science & Technology

    2017-09-01

    19 Figure 7. Solar Portable Alternative Communications Energy System ( SPACES ) Source...sustained operations ashore SPACES solar portable alternative communications energy system STOM ship-to-objective maneuver STSM ship-to-shore movement... Communications Energy System Solar Portable Alternative Communications Energy System ( SPACES ) is a man-portable energy generation system for mounted

  12. 30 CFR 77.601 - Trailing cables or portable cables; temporary splices.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Trailing cables or portable cables; temporary... OF UNDERGROUND COAL MINES Trailing Cables § 77.601 Trailing cables or portable cables; temporary splices. Temporary splices in trailing cables or portable cables shall be made in a workmanlike manner and...

  13. 75 FR 77758 - Approval and Promulgation of Air Quality Implementation Plans; Delaware; Limiting Emissions of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-14

    ... (VOC) from Consumer and Commercial Products, Section 3.0--Portable Fuel Containers. This amendment will... Organic Compounds from Consumer and Commercial Products, Section 3.0--Portable Fuel Containers). I... Products, Section 3.0--Portable Fuel Containers is concerned specifically with the use of portable fuel...

  14. 14 CFR Special Federal Aviation... - Rules for use of portable oxygen concentrator systems on board aircraft

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Rules for use of portable oxygen... portable oxygen concentrator systems on board aircraft Section 1. Applicability—This rule prescribes special operating rules for the use of portable oxygen concentrator units on board civil aircraft. This...

  15. 14 CFR Special Federal Aviation... - Rules for use of portable oxygen concentrator systems on board aircraft

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Rules for use of portable oxygen... portable oxygen concentrator systems on board aircraft Section 1. Applicability—This rule prescribes special operating rules for the use of portable oxygen concentrator units on board civil aircraft. This...

  16. Portable Tablets in Science Museum Learning: Options and Obstacles

    ERIC Educational Resources Information Center

    Gronemann, Sigurd Trolle

    2017-01-01

    Despite the increasing use of portable tablets in learning, their impact has received little attention in research. In five different projects, this media-ethnographic and design-based analysis of the use of portable tablets as a learning resource in science museums investigates how young people's learning with portable tablets matches the…

  17. 46 CFR 120.430 - Portable lights.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Portable lights. 120.430 Section 120.430 Shipping COAST... Systems § 120.430 Portable lights. Each vessel must be equipped with at least two operable portable battery lights. One of these lights must be located at the operating station and the other at the access...

  18. 46 CFR 120.430 - Portable lights.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Portable lights. 120.430 Section 120.430 Shipping COAST... Systems § 120.430 Portable lights. Each vessel must be equipped with at least two operable portable battery lights. One of these lights must be located at the operating station and the other at the access...

  19. 46 CFR 120.430 - Portable lights.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Portable lights. 120.430 Section 120.430 Shipping COAST... Systems § 120.430 Portable lights. Each vessel must be equipped with at least two operable portable battery lights. One of these lights must be located at the operating station and the other at the access...

  20. 46 CFR 120.430 - Portable lights.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Portable lights. 120.430 Section 120.430 Shipping COAST... Systems § 120.430 Portable lights. Each vessel must be equipped with at least two operable portable battery lights. One of these lights must be located at the operating station and the other at the access...

  1. 46 CFR 120.430 - Portable lights.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Portable lights. 120.430 Section 120.430 Shipping COAST... Systems § 120.430 Portable lights. Each vessel must be equipped with at least two operable portable battery lights. One of these lights must be located at the operating station and the other at the access...

  2. PhysioDroid: Combining Wearable Health Sensors and Mobile Devices for a Ubiquitous, Continuous, and Personal Monitoring

    PubMed Central

    Villalonga, Claudia; Damas, Miguel

    2014-01-01

    Technological advances on the development of mobile devices, medical sensors, and wireless communication systems support a new generation of unobtrusive, portable, and ubiquitous health monitoring systems for continuous patient assessment and more personalized health care. There exist a growing number of mobile apps in the health domain; however, little contribution has been specifically provided, so far, to operate this kind of apps with wearable physiological sensors. The PhysioDroid, presented in this paper, provides a personalized means to remotely monitor and evaluate users' conditions. The PhysioDroid system provides ubiquitous and continuous vital signs analysis, such as electrocardiogram, heart rate, respiration rate, skin temperature, and body motion, intended to help empower patients and improve clinical understanding. The PhysioDroid is composed of a wearable monitoring device and an Android app providing gathering, storage, and processing features for the physiological sensor data. The versatility of the developed app allows its use for both average users and specialists, and the reduced cost of the PhysioDroid puts it at the reach of most people. Two exemplary use cases for health assessment and sports training are presented to illustrate the capabilities of the PhysioDroid. Next technical steps include generalization to other mobile platforms and health monitoring devices. PMID:25295301

  3. Experimental high-speed network

    NASA Astrophysics Data System (ADS)

    McNeill, Kevin M.; Klein, William P.; Vercillo, Richard; Alsafadi, Yasser H.; Parra, Miguel V.; Dallas, William J.

    1993-09-01

    Many existing local area networking protocols currently applied in medical imaging were originally designed for relatively low-speed, low-volume networking. These protocols utilize small packet sizes appropriate for text based communication. Local area networks of this type typically provide raw bandwidth under 125 MHz. These older network technologies are not optimized for the low delay, high data traffic environment of a totally digital radiology department. Some current implementations use point-to-point links when greater bandwidth is required. However, the use of point-to-point communications for a total digital radiology department network presents many disadvantages. This paper describes work on an experimental multi-access local area network called XFT. The work includes the protocol specification, and the design and implementation of network interface hardware and software. The protocol specifies the Physical and Data Link layers (OSI layers 1 & 2) for a fiber-optic based token ring providing a raw bandwidth of 500 MHz. The protocol design and implementation of the XFT interface hardware includes many features to optimize image transfer and provide flexibility for additional future enhancements which include: a modular hardware design supporting easy portability to a variety of host system buses, a versatile message buffer design providing 16 MB of memory, and the capability to extend the raw bandwidth of the network to 3.0 GHz.

  4. Lower currents: a new choice for routine testing.

    PubMed

    Backes, John

    2007-01-01

    U.S. NFPA and AAMI standards both recommend a 10A ground bond test and, as has been described above, both 25A and 200mA are also recommended internationally as valid test currents for the in-service testing and inspection of medical electrical equipment. The reality is that both high and low test currents are of value to biomedical engineers and technicians in different circumstances. For benchtop testing in a workshop environment, where required test currents can be applied safely, then it seems likely that high current testing will remain the preferred option. However, for in-service test applications, where the portability and versatility of the tester is a key requirement, modern electronic technology now means that low current testing can now be applied effectively and safely. In summary, by using a low-energy, high current pulse prior to 200 mA test current, the lower test current is preferred for routine field maintenance as this can mean: Increased safety of the operator. Reduced risk of damage to the in-service medical equipment. Smaller test instruments to include valid ground bond measurements. Battery operated test equipment. Increased flexibility of the test engineer due to lightweight test equipment. Cost reduction due to reduced down time of medical equipment. More economical availability of test equipment.

  5. Origami acoustics: using principles of folding structural acoustics for simple and large focusing of sound energy

    NASA Astrophysics Data System (ADS)

    Harne, Ryan L.; Lynd, Danielle T.

    2016-08-01

    Fixed in spatial distribution, arrays of planar, electromechanical acoustic transducers cannot adapt their wave energy focusing abilities unless each transducer is externally controlled, creating challenges for the implementation and portability of such beamforming systems. Recently, planar, origami-based structural tessellations are found to facilitate great versatility in system function and properties through kinematic folding. In this research we bridge the physics of acoustics and origami-based design to discover that the simple topological reconfigurations of a Miura-ori-based acoustic array yield many orders of magnitude worth of reversible change in wave energy focusing: a potential for acoustic field morphing easily obtained through deployable, tessellated architectures. Our experimental and theoretical studies directly translate the roles of folding the tessellated array to the adaptations in spectral and spatial wave propagation sensitivities for far field energy transmission. It is shown that kinematic folding rules and flat-foldable tessellated arrays collectively provide novel solutions to the long-standing challenges of conventional, electronically-steered acoustic beamformers. While our examples consider sound radiation from the foldable array in air, linear acoustic reciprocity dictates that the findings may inspire new innovations for acoustic receivers, e.g. adaptive sound absorbers and microphone arrays, as well as concepts that include water-borne waves.

  6. Data processing workflows from low-cost digital survey to various applications: three case studies of Chinese historic architecture

    NASA Astrophysics Data System (ADS)

    Sun, Z.; Cao, Y. K.

    2015-08-01

    The paper focuses on the versatility of data processing workflows ranging from BIM-based survey to structural analysis and reverse modeling. In China nowadays, a large number of historic architecture are in need of restoration, reinforcement and renovation. But the architects are not prepared for the conversion from the booming AEC industry to architectural preservation. As surveyors working with architects in such projects, we have to develop efficient low-cost digital survey workflow robust to various types of architecture, and to process the captured data for architects. Although laser scanning yields high accuracy in architectural heritage documentation and the workflow is quite straightforward, the cost and portability hinder it from being used in projects where budget and efficiency are of prime concern. We integrate Structure from Motion techniques with UAV and total station in data acquisition. The captured data is processed for various purposes illustrated with three case studies: the first one is as-built BIM for a historic building based on registered point clouds according to Ground Control Points; The second one concerns structural analysis for a damaged bridge using Finite Element Analysis software; The last one relates to parametric automated feature extraction from captured point clouds for reverse modeling and fabrication.

  7. Simulation-Based Cutaneous Surgical-Skill Training on a Chicken-Skin Bench Model in a Medical Undergraduate Program

    PubMed Central

    Denadai, Rafael; Saad-Hossne, Rogério; Martinhão Souto, Luís Ricardo

    2013-01-01

    Background: Because of ethical and medico-legal aspects involved in the training of cutaneous surgical skills on living patients, human cadavers and living animals, it is necessary the search for alternative and effective forms of training simulation. Aims: To propose and describe an alternative methodology for teaching and learning the principles of cutaneous surgery in a medical undergraduate program by using a chicken-skin bench model. Materials and Methods: One instructor for every four students, teaching materials on cutaneous surgical skills, chicken trunks, wings, or thighs, a rigid platform support, needled threads, needle holders, surgical blades with scalpel handles, rat-tooth tweezers, scissors, and marking pens were necessary for training simulation. Results: A proposal for simulation-based training on incision, suture, biopsy, and on reconstruction techniques using a chicken-skin bench model distributed in several sessions and with increasing levels of difficultywas structured. Both feedback and objective evaluations always directed to individual students were also outlined. Conclusion: The teaching of a methodology for the principles of cutaneous surgery using a chicken-skin bench model versatile, portable, easy to assemble, and inexpensive is an alternative and complementary option to the armamentarium of methods based on other bench models described. PMID:23723471

  8. PhysioDroid: combining wearable health sensors and mobile devices for a ubiquitous, continuous, and personal monitoring.

    PubMed

    Banos, Oresti; Villalonga, Claudia; Damas, Miguel; Gloesekoetter, Peter; Pomares, Hector; Rojas, Ignacio

    2014-01-01

    Technological advances on the development of mobile devices, medical sensors, and wireless communication systems support a new generation of unobtrusive, portable, and ubiquitous health monitoring systems for continuous patient assessment and more personalized health care. There exist a growing number of mobile apps in the health domain; however, little contribution has been specifically provided, so far, to operate this kind of apps with wearable physiological sensors. The PhysioDroid, presented in this paper, provides a personalized means to remotely monitor and evaluate users' conditions. The PhysioDroid system provides ubiquitous and continuous vital signs analysis, such as electrocardiogram, heart rate, respiration rate, skin temperature, and body motion, intended to help empower patients and improve clinical understanding. The PhysioDroid is composed of a wearable monitoring device and an Android app providing gathering, storage, and processing features for the physiological sensor data. The versatility of the developed app allows its use for both average users and specialists, and the reduced cost of the PhysioDroid puts it at the reach of most people. Two exemplary use cases for health assessment and sports training are presented to illustrate the capabilities of the PhysioDroid. Next technical steps include generalization to other mobile platforms and health monitoring devices.

  9. Lab-on-a-Drone: Toward Pinpoint Deployment of Smartphone-Enabled Nucleic Acid-Based Diagnostics for Mobile Health Care

    PubMed Central

    2016-01-01

    We introduce a portable biochemical analysis platform for rapid field deployment of nucleic acid-based diagnostics using consumer-class quadcopter drones. This approach exploits the ability to isothermally perform the polymerase chain reaction (PCR) with a single heater, enabling the system to be operated using standard 5 V USB sources that power mobile devices (via battery, solar, or hand crank action). Time-resolved fluorescence detection and quantification is achieved using a smartphone camera and integrated image analysis app. Standard sample preparation is enabled by leveraging the drone’s motors as centrifuges via 3D printed snap-on attachments. These advancements make it possible to build a complete DNA/RNA analysis system at a cost of ∼$50 ($US). Our instrument is rugged and versatile, enabling pinpoint deployment of sophisticated diagnostics to distributed field sites. This capability is demonstrated by successful in-flight replication of Staphylococcus aureus and λ-phage DNA targets in under 20 min. The ability to perform rapid in-flight assays with smartphone connectivity eliminates delays between sample collection and analysis so that test results can be delivered in minutes, suggesting new possibilities for drone-based systems to function in broader and more sophisticated roles beyond cargo transport and imaging. PMID:26898247

  10. Lab-on-a-Drone: Toward Pinpoint Deployment of Smartphone-Enabled Nucleic Acid-Based Diagnostics for Mobile Health Care.

    PubMed

    Priye, Aashish; Wong, Season; Bi, Yuanpeng; Carpio, Miguel; Chang, Jamison; Coen, Mauricio; Cope, Danielle; Harris, Jacob; Johnson, James; Keller, Alexandra; Lim, Richard; Lu, Stanley; Millard, Alex; Pangelinan, Adriano; Patel, Neal; Smith, Luke; Chan, Kamfai; Ugaz, Victor M

    2016-05-03

    We introduce a portable biochemical analysis platform for rapid field deployment of nucleic acid-based diagnostics using consumer-class quadcopter drones. This approach exploits the ability to isothermally perform the polymerase chain reaction (PCR) with a single heater, enabling the system to be operated using standard 5 V USB sources that power mobile devices (via battery, solar, or hand crank action). Time-resolved fluorescence detection and quantification is achieved using a smartphone camera and integrated image analysis app. Standard sample preparation is enabled by leveraging the drone's motors as centrifuges via 3D printed snap-on attachments. These advancements make it possible to build a complete DNA/RNA analysis system at a cost of ∼$50 ($US). Our instrument is rugged and versatile, enabling pinpoint deployment of sophisticated diagnostics to distributed field sites. This capability is demonstrated by successful in-flight replication of Staphylococcus aureus and λ-phage DNA targets in under 20 min. The ability to perform rapid in-flight assays with smartphone connectivity eliminates delays between sample collection and analysis so that test results can be delivered in minutes, suggesting new possibilities for drone-based systems to function in broader and more sophisticated roles beyond cargo transport and imaging.

  11. Hands-On Practical Chemistry for All: Why and How?

    NASA Astrophysics Data System (ADS)

    Bradley, John D.; Durbach, S.; Bell, B.; Mungarulire, J.; Kimel, H.

    1998-11-01

    Practical work in chemistry is invariably described as essential in chemical education, and a variety of aims is claimed for it. Yet in schools around the world it is frequently absent from the real curriculum. Although some of the explanations advanced for this conundrum are little more than excuses, there is truth in the cost explanation. In this article we report on our development of a system based on microscale chemistry kits for individual students. These reusable kits comprise a number of components specially designed around a Comboplate made of optically clear plastic. The kits are supplied in individual zip-lock bags with a variety of configurations to suit different grades and curricula. Chemicals are supplied as solids and prepared solutions in quantities suitable for a whole class for one year, and student worksheets are available. The total system is cost-effective, safe, environmentally friendly, and versatile. The system has been very well received in both wealthy and poor contexts and countries by both teachers and students. It is so convenient and user-friendly it appeals to teachers. For students, pride of ownership is tapped by the individual kits. Their portability facilitates fieldwork and also distance learning. The system, developed through academic-industrial cooperation, may well achieve a global revolution in chemistry teaching and learning.

  12. Light weight, high-speed, and self-powered wireless fiber optic sensor (WiFOS) structural health monitor system for avionics and aerospace environments

    NASA Astrophysics Data System (ADS)

    Mendoza, Edgar A.; Kempen, Cornelia; Sun, Sunjian; Esterkin, Yan

    2014-09-01

    This paper describes recent progress towards the development of an innovative light weight, high-speed, and selfpowered wireless fiber optic sensor (WiFOS™) structural health monitor system suitable for the onboard and in-flight unattended detection, localization, and classification of load, fatigue, and structural damage in advanced composite materials commonly used in avionics and aerospace systems. The WiFOS™ system is based on ROI's advancements on monolithic photonic integrated circuit microchip technology, integrated with smart power management, on-board data processing, wireless data transmission optoelectronics, and self-power using energy harvesting tools such as solar, vibration, thermoelectric, and magneto-electric. The self-powered, wireless WiFOS™ system offers a versatile and powerful SHM tool to enhance the reliability and safety of avionics platforms, jet fighters, helicopters, commercial aircraft that use lightweight composite material structures, by providing comprehensive information about the structural integrity of the structure from a large number of locations. Immediate SHM applications are found in rotorcraft and aircraft, ships, submarines, and in next generation weapon systems, and in commercial oil and petrochemical, aerospace industries, civil structures, power utilities, portable medical devices, and biotechnology, homeland security and a wide spectrum of other applications.

  13. Sensitivity control of optical fiber biosensors utilizing turnaround point long period gratings with self-assembled polymer coatings

    NASA Astrophysics Data System (ADS)

    Gifford, Erika; Wang, Z.; Ramachandran, S.; Heflin, J. R.

    2007-09-01

    Ionic self-assembled multilayers (ISAMs) adsorbed on long period fiber gratings (LPGs) can serve as an inexpensive, robust, portable, biosensor platform. The ISAM technique is a layer-by-layer deposition technique that creates thin films on the nanoscale level. The combination of ISAMs with LPGs yields exceptional sensitivity of the optical fiber transmission spectrum. We have shown theoretically that the resonant wavelength shift for a thin-film coated LPG can be caused by the variation of the film's refractive index and/or the variation of the thickness of the film. We have experimentally demonstrated that the deposition of nm-thick ISAM films on LPGs induces shifts in the resonant wavelength of > 1.6 nm per nm of thin film. It has also been shown that the sensitivity of the LPG to the thickness of the ISAM film increases with increased film thickness. We have further demonstrated that ISAM-coated LPGs can function effectively as biosensors by using the biotin-streptavidin system and by using the Bacillus anthracis (Anthrax) antibody- PA (Protective Antigen) system. Experiments have been successfully performed in both air and solution, which illustrates the versatility of the biosensor. The results confirm that ISAM-LPGs yield a reusable, thermally-stable, and robust platform for designing and building efficient optical biosensors.

  14. Obstructive sleep apnea, seizures, and childhood apraxia of speech.

    PubMed

    Caspari, Susan S; Strand, Edythe A; Kotagal, Suresh; Bergqvist, Christina

    2008-06-01

    Associations between obstructive sleep apnea and motor speech disorders in adults have been suggested, though little has been written about possible effects of sleep apnea on speech acquisition in children with motor speech disorders. This report details the medical and speech history of a nonverbal child with seizures and severe apraxia of speech. For 6 years, he made no functional gains in speech production, despite intensive speech therapy. After tonsillectomy for obstructive sleep apnea at age 6 years, he experienced a reduction in seizures and rapid growth in speech production. The findings support a relationship between obstructive sleep apnea and childhood apraxia of speech. The rather late diagnosis and treatment of obstructive sleep apnea, especially in light of what was such a life-altering outcome (gaining functional speech), has significant implications. Most speech sounds develop during ages 2-5 years, which is also the peak time of occurrence of adenotonsillar hypertrophy and childhood obstructive sleep apnea. Hence it is important to establish definitive diagnoses, and to consider early and more aggressive treatments for obstructive sleep apnea, in children with motor speech disorders.

  15. Visual Phonetic Processing Localized Using Speech and Non-Speech Face Gestures in Video and Point-Light Displays

    PubMed Central

    Bernstein, Lynne E.; Jiang, Jintao; Pantazis, Dimitrios; Lu, Zhong-Lin; Joshi, Anand

    2011-01-01

    The talking face affords multiple types of information. To isolate cortical sites with responsibility for integrating linguistically relevant visual speech cues, speech and non-speech face gestures were presented in natural video and point-light displays during fMRI scanning at 3.0T. Participants with normal hearing viewed the stimuli and also viewed localizers for the fusiform face area (FFA), the lateral occipital complex (LOC), and the visual motion (V5/MT) regions of interest (ROIs). The FFA, the LOC, and V5/MT were significantly less activated for speech relative to non-speech and control stimuli. Distinct activation of the posterior superior temporal sulcus and the adjacent middle temporal gyrus to speech, independent of media, was obtained in group analyses. Individual analyses showed that speech and non-speech stimuli were associated with adjacent but different activations, with the speech activations more anterior. We suggest that the speech activation area is the temporal visual speech area (TVSA), and that it can be localized with the combination of stimuli used in this study. PMID:20853377

  16. Relationship between speech motor control and speech intelligibility in children with speech sound disorders.

    PubMed

    Namasivayam, Aravind Kumar; Pukonen, Margit; Goshulak, Debra; Yu, Vickie Y; Kadis, Darren S; Kroll, Robert; Pang, Elizabeth W; De Nil, Luc F

    2013-01-01

    The current study was undertaken to investigate the impact of speech motor issues on the speech intelligibility of children with moderate to severe speech sound disorders (SSD) within the context of the PROMPT intervention approach. The word-level Children's Speech Intelligibility Measure (CSIM), the sentence-level Beginner's Intelligibility Test (BIT) and tests of speech motor control and articulation proficiency were administered to 12 children (3:11 to 6:7 years) before and after PROMPT therapy. PROMPT treatment was provided for 45 min twice a week for 8 weeks. Twenty-four naïve adult listeners aged 22-46 years judged the intelligibility of the words and sentences. For CSIM, each time a recorded word was played to the listeners they were asked to look at a list of 12 words (multiple-choice format) and circle the word while for BIT sentences, the listeners were asked to write down everything they heard. Words correctly circled (CSIM) or transcribed (BIT) were averaged across three naïve judges to calculate percentage speech intelligibility. Speech intelligibility at both the word and sentence level was significantly correlated with speech motor control, but not articulatory proficiency. Further, the severity of speech motor planning and sequencing issues may potentially be a limiting factor in connected speech intelligibility and highlights the need to target these issues early and directly in treatment. The reader will be able to: (1) outline the advantages and disadvantages of using word- and sentence-level speech intelligibility tests; (2) describe the impact of speech motor control and articulatory proficiency on speech intelligibility; and (3) describe how speech motor control and speech intelligibility data may provide critical information to aid treatment planning. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. A common functional neural network for overt production of speech and gesture.

    PubMed

    Marstaller, L; Burianová, H

    2015-01-22

    The perception of co-speech gestures, i.e., hand movements that co-occur with speech, has been investigated by several studies. The results show that the perception of co-speech gestures engages a core set of frontal, temporal, and parietal areas. However, no study has yet investigated the neural processes underlying the production of co-speech gestures. Specifically, it remains an open question whether Broca's area is central to the coordination of speech and gestures as has been suggested previously. The objective of this study was to use functional magnetic resonance imaging to (i) investigate the regional activations underlying overt production of speech, gestures, and co-speech gestures, and (ii) examine functional connectivity with Broca's area. We hypothesized that co-speech gesture production would activate frontal, temporal, and parietal regions that are similar to areas previously found during co-speech gesture perception and that both speech and gesture as well as co-speech gesture production would engage a neural network connected to Broca's area. Whole-brain analysis confirmed our hypothesis and showed that co-speech gesturing did engage brain areas that form part of networks known to subserve language and gesture. Functional connectivity analysis further revealed a functional network connected to Broca's area that is common to speech, gesture, and co-speech gesture production. This network consists of brain areas that play essential roles in motor control, suggesting that the coordination of speech and gesture is mediated by a shared motor control network. Our findings thus lend support to the idea that speech can influence co-speech gesture production on a motoric level. Copyright © 2014 IBRO. Published by Elsevier Ltd. All rights reserved.

  18. Female voice communications in high level aircraft cockpit noises--part II: vocoder and automatic speech recognition systems.

    PubMed

    Nixon, C; Anderson, T; Morris, L; McCavitt, A; McKinley, R; Yeager, D; McDaniel, M

    1998-11-01

    The intelligibility of female and male speech is equivalent under most ordinary living conditions. However, due to small differences between their acoustic speech signals, called speech spectra, one can be more or less intelligible than the other in certain situations such as high levels of noise. Anecdotal information, supported by some empirical observations, suggests that some of the high intensity noise spectra of military aircraft cockpits may degrade the intelligibility of female speech more than that of male speech. In an applied research study, the intelligibility of female and male speech was measured in several high level aircraft cockpit noise conditions experienced in military aviation. In Part I, (Nixon CW, et al. Aviat Space Environ Med 1998; 69:675-83) female speech intelligibility measured in the spectra and levels of aircraft cockpit noises and with noise-canceling microphones was lower than that of the male speech in all conditions. However, the differences were small and only those at some of the highest noise levels were significant. Although speech intelligibility of both genders was acceptable during normal cruise noises, improvements are required in most of the highest levels of noise created during maximum aircraft operating conditions. These results are discussed in a Part I technical report. This Part II report examines the intelligibility in the same aircraft cockpit noises of vocoded female and male speech and the accuracy with which female and male speech in some of the cockpit noises were understood by automatic speech recognition systems. The intelligibility of vocoded female speech was generally the same as that of vocoded male speech. No significant differences were measured between the recognition accuracy of male and female speech by the automatic speech recognition systems. The intelligibility of female and male speech was equivalent for these conditions.

  19. Brain networks engaged in audiovisual integration during speech perception revealed by persistent homology-based network filtration.

    PubMed

    Kim, Heejung; Hahm, Jarang; Lee, Hyekyoung; Kang, Eunjoo; Kang, Hyejin; Lee, Dong Soo

    2015-05-01

    The human brain naturally integrates audiovisual information to improve speech perception. However, in noisy environments, understanding speech is difficult and may require much effort. Although the brain network is supposed to be engaged in speech perception, it is unclear how speech-related brain regions are connected during natural bimodal audiovisual or unimodal speech perception with counterpart irrelevant noise. To investigate the topological changes of speech-related brain networks at all possible thresholds, we used a persistent homological framework through hierarchical clustering, such as single linkage distance, to analyze the connected component of the functional network during speech perception using functional magnetic resonance imaging. For speech perception, bimodal (audio-visual speech cue) or unimodal speech cues with counterpart irrelevant noise (auditory white-noise or visual gum-chewing) were delivered to 15 subjects. In terms of positive relationship, similar connected components were observed in bimodal and unimodal speech conditions during filtration. However, during speech perception by congruent audiovisual stimuli, the tighter couplings of left anterior temporal gyrus-anterior insula component and right premotor-visual components were observed than auditory or visual speech cue conditions, respectively. Interestingly, visual speech is perceived under white noise by tight negative coupling in the left inferior frontal region-right anterior cingulate, left anterior insula, and bilateral visual regions, including right middle temporal gyrus, right fusiform components. In conclusion, the speech brain network is tightly positively or negatively connected, and can reflect efficient or effortful processes during natural audiovisual integration or lip-reading, respectively, in speech perception.

  20. Sensorimotor Oscillations Prior to Speech Onset Reflect Altered Motor Networks in Adults Who Stutter

    PubMed Central

    Mersov, Anna-Maria; Jobst, Cecilia; Cheyne, Douglas O.; De Nil, Luc

    2016-01-01

    Adults who stutter (AWS) have demonstrated atypical coordination of motor and sensory regions during speech production. Yet little is known of the speech-motor network in AWS in the brief time window preceding audible speech onset. The purpose of the current study was to characterize neural oscillations in the speech-motor network during preparation for and execution of overt speech production in AWS using magnetoencephalography (MEG). Twelve AWS and 12 age-matched controls were presented with 220 words, each word embedded in a carrier phrase. Controls were presented with the same word list as their matched AWS participant. Neural oscillatory activity was localized using minimum-variance beamforming during two time periods of interest: speech preparation (prior to speech onset) and speech execution (following speech onset). Compared to controls, AWS showed stronger beta (15–25 Hz) suppression in the speech preparation stage, followed by stronger beta synchronization in the bilateral mouth motor cortex. AWS also recruited the right mouth motor cortex significantly earlier in the speech preparation stage compared to controls. Exaggerated motor preparation is discussed in the context of reduced coordination in the speech-motor network of AWS. It is further proposed that exaggerated beta synchronization may reflect a more strongly inhibited motor system that requires a stronger beta suppression to disengage prior to speech initiation. These novel findings highlight critical differences in the speech-motor network of AWS that occur prior to speech onset and emphasize the need to investigate further the speech-motor assembly in the stuttering population. PMID:27642279

  1. The Speech multi features fusion perceptual hash algorithm based on tensor decomposition

    NASA Astrophysics Data System (ADS)

    Huang, Y. B.; Fan, M. H.; Zhang, Q. Y.

    2018-03-01

    With constant progress in modern speech communication technologies, the speech data is prone to be attacked by the noise or maliciously tampered. In order to make the speech perception hash algorithm has strong robustness and high efficiency, this paper put forward a speech perception hash algorithm based on the tensor decomposition and multi features is proposed. This algorithm analyses the speech perception feature acquires each speech component wavelet packet decomposition. LPCC, LSP and ISP feature of each speech component are extracted to constitute the speech feature tensor. Speech authentication is done by generating the hash values through feature matrix quantification which use mid-value. Experimental results showing that the proposed algorithm is robust for content to maintain operations compared with similar algorithms. It is able to resist the attack of the common background noise. Also, the algorithm is highly efficiency in terms of arithmetic, and is able to meet the real-time requirements of speech communication and complete the speech authentication quickly.

  2. Associations between speech features and phenotypic severity in Treacher Collins syndrome

    PubMed Central

    2014-01-01

    Background Treacher Collins syndrome (TCS, OMIM 154500) is a rare congenital disorder of craniofacial development. Characteristic hypoplastic malformations of the ears, zygomatic arch, mandible and pharynx have been described in detail. However, reports on the impact of these malformations on speech are few. Exploring speech features and investigating if speech function is related to phenotypic severity are essential for optimizing follow-up and treatment. Methods Articulation, nasal resonance, voice and intelligibility were examined in 19 individuals (5–74 years, median 34 years) divided into three groups comprising children 5–10 years (n = 4), adolescents 11–18 years (n = 4) and adults 29 years and older (n = 11). A speech composite score (0–6) was calculated to reflect the variability of speech deviations. TCS severity scores of phenotypic expression and total scores of Nordic Orofacial Test-Screening (NOT-S) measuring orofacial dysfunction were used in analyses of correlation with speech characteristics (speech composite scores). Results Children and adolescents presented with significantly higher speech composite scores (median 4, range 1–6) than adults (median 1, range 0–5). Nearly all children and adolescents (6/8) displayed speech deviations of articulation, nasal resonance and voice, while only three adults were identified with multiple speech aberrations. The variability of speech dysfunction in TCS was exhibited by individual combinations of speech deviations in 13/19 participants. The speech composite scores correlated with TCS severity scores and NOT-S total scores. Speech composite scores higher than 4 were associated with cleft palate. The percent of intelligible words in connected speech was significantly lower in children and adolescents (median 77%, range 31–99) than in adults (98%, range 93–100). Intelligibility of speech among the children was markedly inconsistent and clearly affecting the understandability. Conclusions Multiple speech deviations were identified in children, adolescents and a subgroup of adults with TCS. Only children displayed markedly reduced intelligibility. Speech was significantly correlated with phenotypic severity of TCS and orofacial dysfunction. Follow-up and treatment of speech should still be focused on young patients, but some adults with TCS seem to require continuing speech and language pathology services. PMID:24775909

  3. Associations between speech features and phenotypic severity in Treacher Collins syndrome.

    PubMed

    Asten, Pamela; Akre, Harriet; Persson, Christina

    2014-04-28

    Treacher Collins syndrome (TCS, OMIM 154500) is a rare congenital disorder of craniofacial development. Characteristic hypoplastic malformations of the ears, zygomatic arch, mandible and pharynx have been described in detail. However, reports on the impact of these malformations on speech are few. Exploring speech features and investigating if speech function is related to phenotypic severity are essential for optimizing follow-up and treatment. Articulation, nasal resonance, voice and intelligibility were examined in 19 individuals (5-74 years, median 34 years) divided into three groups comprising children 5-10 years (n = 4), adolescents 11-18 years (n = 4) and adults 29 years and older (n = 11). A speech composite score (0-6) was calculated to reflect the variability of speech deviations. TCS severity scores of phenotypic expression and total scores of Nordic Orofacial Test-Screening (NOT-S) measuring orofacial dysfunction were used in analyses of correlation with speech characteristics (speech composite scores). Children and adolescents presented with significantly higher speech composite scores (median 4, range 1-6) than adults (median 1, range 0-5). Nearly all children and adolescents (6/8) displayed speech deviations of articulation, nasal resonance and voice, while only three adults were identified with multiple speech aberrations. The variability of speech dysfunction in TCS was exhibited by individual combinations of speech deviations in 13/19 participants. The speech composite scores correlated with TCS severity scores and NOT-S total scores. Speech composite scores higher than 4 were associated with cleft palate. The percent of intelligible words in connected speech was significantly lower in children and adolescents (median 77%, range 31-99) than in adults (98%, range 93-100). Intelligibility of speech among the children was markedly inconsistent and clearly affecting the understandability. Multiple speech deviations were identified in children, adolescents and a subgroup of adults with TCS. Only children displayed markedly reduced intelligibility. Speech was significantly correlated with phenotypic severity of TCS and orofacial dysfunction. Follow-up and treatment of speech should still be focused on young patients, but some adults with TCS seem to require continuing speech and language pathology services.

  4. Conflict monitoring in speech processing: An fMRI study of error detection in speech production and perception.

    PubMed

    Gauvin, Hanna S; De Baene, Wouter; Brass, Marcel; Hartsuiker, Robert J

    2016-02-01

    To minimize the number of errors in speech, and thereby facilitate communication, speech is monitored before articulation. It is, however, unclear at which level during speech production monitoring takes place, and what mechanisms are used to detect and correct errors. The present study investigated whether internal verbal monitoring takes place through the speech perception system, as proposed by perception-based theories of speech monitoring, or whether mechanisms independent of perception are applied, as proposed by production-based theories of speech monitoring. With the use of fMRI during a tongue twister task we observed that error detection in internal speech during noise-masked overt speech production and error detection in speech perception both recruit the same neural network, which includes pre-supplementary motor area (pre-SMA), dorsal anterior cingulate cortex (dACC), anterior insula (AI), and inferior frontal gyrus (IFG). Although production and perception recruit similar areas, as proposed by perception-based accounts, we did not find activation in superior temporal areas (which are typically associated with speech perception) during internal speech monitoring in speech production as hypothesized by these accounts. On the contrary, results are highly compatible with a domain general approach to speech monitoring, by which internal speech monitoring takes place through detection of conflict between response options, which is subsequently resolved by a domain general executive center (e.g., the ACC). Copyright © 2015 Elsevier Inc. All rights reserved.

  5. A novel radar sensor for the non-contact detection of speech signals.

    PubMed

    Jiao, Mingke; Lu, Guohua; Jing, Xijing; Li, Sheng; Li, Yanfeng; Wang, Jianqi

    2010-01-01

    Different speech detection sensors have been developed over the years but they are limited by the loss of high frequency speech energy, and have restricted non-contact detection due to the lack of penetrability. This paper proposes a novel millimeter microwave radar sensor to detect speech signals. The utilization of a high operating frequency and a superheterodyne receiver contributes to the high sensitivity of the radar sensor for small sound vibrations. In addition, the penetrability of microwaves allows the novel sensor to detect speech signals through nonmetal barriers. Results show that the novel sensor can detect high frequency speech energies and that the speech quality is comparable to traditional microphone speech. Moreover, the novel sensor can detect speech signals through a nonmetal material of a certain thickness between the sensor and the subject. Thus, the novel speech sensor expands traditional speech detection techniques and provides an exciting alternative for broader application prospects.

  6. A Novel Radar Sensor for the Non-Contact Detection of Speech Signals

    PubMed Central

    Jiao, Mingke; Lu, Guohua; Jing, Xijing; Li, Sheng; Li, Yanfeng; Wang, Jianqi

    2010-01-01

    Different speech detection sensors have been developed over the years but they are limited by the loss of high frequency speech energy, and have restricted non-contact detection due to the lack of penetrability. This paper proposes a novel millimeter microwave radar sensor to detect speech signals. The utilization of a high operating frequency and a superheterodyne receiver contributes to the high sensitivity of the radar sensor for small sound vibrations. In addition, the penetrability of microwaves allows the novel sensor to detect speech signals through nonmetal barriers. Results show that the novel sensor can detect high frequency speech energies and that the speech quality is comparable to traditional microphone speech. Moreover, the novel sensor can detect speech signals through a nonmetal material of a certain thickness between the sensor and the subject. Thus, the novel speech sensor expands traditional speech detection techniques and provides an exciting alternative for broader application prospects. PMID:22399895

  7. Acoustics in human communication: evolving ideas about the nature of speech.

    PubMed

    Cooper, F S

    1980-07-01

    This paper discusses changes in attitude toward the nature of speech during the past half century. After reviewing early views on the subject, it considers the role of speech spectrograms, speech articulation, speech perception, messages and computers, and the nature of fluent speech.

  8. Music and Speech Perception in Children Using Sung Speech

    PubMed Central

    Nie, Yingjiu; Galvin, John J.; Morikawa, Michael; André, Victoria; Wheeler, Harley; Fu, Qian-Jie

    2018-01-01

    This study examined music and speech perception in normal-hearing children with some or no musical training. Thirty children (mean age = 11.3 years), 15 with and 15 without formal music training participated in the study. Music perception was measured using a melodic contour identification (MCI) task; stimuli were a piano sample or sung speech with a fixed timbre (same word for each note) or a mixed timbre (different words for each note). Speech perception was measured in quiet and in steady noise using a matrix-styled sentence recognition task; stimuli were naturally intonated speech or sung speech with a fixed pitch (same note for each word) or a mixed pitch (different notes for each word). Significant musician advantages were observed for MCI and speech in noise but not for speech in quiet. MCI performance was significantly poorer with the mixed timbre stimuli. Speech performance in noise was significantly poorer with the fixed or mixed pitch stimuli than with spoken speech. Across all subjects, age at testing and MCI performance were significantly correlated with speech performance in noise. MCI and speech performance in quiet was significantly poorer for children than for adults from a related study using the same stimuli and tasks; speech performance in noise was significantly poorer for young than for older children. Long-term music training appeared to benefit melodic pitch perception and speech understanding in noise in these pediatric listeners. PMID:29609496

  9. Music and Speech Perception in Children Using Sung Speech.

    PubMed

    Nie, Yingjiu; Galvin, John J; Morikawa, Michael; André, Victoria; Wheeler, Harley; Fu, Qian-Jie

    2018-01-01

    This study examined music and speech perception in normal-hearing children with some or no musical training. Thirty children (mean age = 11.3 years), 15 with and 15 without formal music training participated in the study. Music perception was measured using a melodic contour identification (MCI) task; stimuli were a piano sample or sung speech with a fixed timbre (same word for each note) or a mixed timbre (different words for each note). Speech perception was measured in quiet and in steady noise using a matrix-styled sentence recognition task; stimuli were naturally intonated speech or sung speech with a fixed pitch (same note for each word) or a mixed pitch (different notes for each word). Significant musician advantages were observed for MCI and speech in noise but not for speech in quiet. MCI performance was significantly poorer with the mixed timbre stimuli. Speech performance in noise was significantly poorer with the fixed or mixed pitch stimuli than with spoken speech. Across all subjects, age at testing and MCI performance were significantly correlated with speech performance in noise. MCI and speech performance in quiet was significantly poorer for children than for adults from a related study using the same stimuli and tasks; speech performance in noise was significantly poorer for young than for older children. Long-term music training appeared to benefit melodic pitch perception and speech understanding in noise in these pediatric listeners.

  10. Portable Chemical Sterilizer (PCS) for Surgical Instruments

    DTIC Science & Technology

    2004-12-01

    PORTABLE CHEMICAL STERILIZER (PCS) FOR SURGICAL INSTRUMENTS CJ Doona*, FE Feeherry, MA Curtin‡, K Kustin‡, S Kandlikar‡ U.S. Army-Soldier...denotes Contractors) Biomedical Technologies ABSTRACT A novel device called the Portable Chemical Sterilizer (PCS) has been developed for the...rapid, safe, portable, power-free, and convenient sterilization of objects or surfaces contaminated with pathogenic microorganisms that cause

  11. 46 CFR 98.30-9 - Stowage of portable tanks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Stowage of portable tanks. 98.30-9 Section 98.30-9... CONSTRUCTION, ARRANGEMENT, AND OTHER PROVISIONS FOR CERTAIN DANGEROUS CARGOES IN BULK Portable Tanks § 98.30-9 Stowage of portable tanks. (a) No person may operate a vessel to which this subpart applies unless each...

  12. 46 CFR 98.30-9 - Stowage of portable tanks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Stowage of portable tanks. 98.30-9 Section 98.30-9... CONSTRUCTION, ARRANGEMENT, AND OTHER PROVISIONS FOR CERTAIN DANGEROUS CARGOES IN BULK Portable Tanks § 98.30-9 Stowage of portable tanks. (a) No person may operate a vessel to which this subpart applies unless each...

  13. THE COMPREHENSION OF RAPID SPEECH BY THE BLIND, PART III.

    ERIC Educational Resources Information Center

    FOULKE, EMERSON

    A REVIEW OF THE RESEARCH ON THE COMPREHENSION OF RAPID SPEECH BY THE BLIND IDENTIFIES FIVE METHODS OF SPEECH COMPRESSION--SPEECH CHANGING, ELECTROMECHANICAL SAMPLING, COMPUTER SAMPLING, SPEECH SYNTHESIS, AND FREQUENCY DIVIDING WITH THE HARMONIC COMPRESSOR. THE SPEECH CHANGING AND ELECTROMECHANICAL SAMPLING METHODS AND THE NECESSARY APPARATUS HAVE…

  14. Predicting Speech Intelligibility with a Multiple Speech Subsystems Approach in Children with Cerebral Palsy

    ERIC Educational Resources Information Center

    Lee, Jimin; Hustad, Katherine C.; Weismer, Gary

    2014-01-01

    Purpose: Speech acoustic characteristics of children with cerebral palsy (CP) were examined with a multiple speech subsystems approach; speech intelligibility was evaluated using a prediction model in which acoustic measures were selected to represent three speech subsystems. Method: Nine acoustic variables reflecting different subsystems, and…

  15. 75 FR 5794 - Notice of Public Information Collection Being Reviewed by the Federal Communications Commission...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ... Speech-to-Speech Services for Individuals with Hearing and Speech Disabilities; IP Captioned Telephone..., the Commission released Telecommunications Relay Services and Speech-to-Speech Services for Individuals with Hearing and Speech Disabilities, CC Docket No. 98-67, Declaratory Ruling, published at 68 FR...

  16. Extensions to the Speech Disorders Classification System (SDCS)

    ERIC Educational Resources Information Center

    Shriberg, Lawrence D.; Fourakis, Marios; Hall, Sheryl D.; Karlsson, Heather B.; Lohmeier, Heather L.; McSweeny, Jane L.; Potter, Nancy L.; Scheer-Cohen, Alison R.; Strand, Edythe A.; Tilkens, Christie M.; Wilson, David L.

    2010-01-01

    This report describes three extensions to a classification system for paediatric speech sound disorders termed the Speech Disorders Classification System (SDCS). Part I describes a classification extension to the SDCS to differentiate motor speech disorders from speech delay and to differentiate among three sub-types of motor speech disorders.…

  17. Linguistic contributions to speech-on-speech masking for native and non-native listeners: language familiarity and semantic content.

    PubMed

    Brouwer, Susanne; Van Engen, Kristin J; Calandruccio, Lauren; Bradlow, Ann R

    2012-02-01

    This study examined whether speech-on-speech masking is sensitive to variation in the degree of similarity between the target and the masker speech. Three experiments investigated whether speech-in-speech recognition varies across different background speech languages (English vs Dutch) for both English and Dutch targets, as well as across variation in the semantic content of the background speech (meaningful vs semantically anomalous sentences), and across variation in listener status vis-à-vis the target and masker languages (native, non-native, or unfamiliar). The results showed that the more similar the target speech is to the masker speech (e.g., same vs different language, same vs different levels of semantic content), the greater the interference on speech recognition accuracy. Moreover, the listener's knowledge of the target and the background language modulate the size of the release from masking. These factors had an especially strong effect on masking effectiveness in highly unfavorable listening conditions. Overall this research provided evidence that that the degree of target-masker similarity plays a significant role in speech-in-speech recognition. The results also give insight into how listeners assign their resources differently depending on whether they are listening to their first or second language. © 2012 Acoustical Society of America

  18. Linguistic contributions to speech-on-speech masking for native and non-native listeners: Language familiarity and semantic content

    PubMed Central

    Brouwer, Susanne; Van Engen, Kristin J.; Calandruccio, Lauren; Bradlow, Ann R.

    2012-01-01

    This study examined whether speech-on-speech masking is sensitive to variation in the degree of similarity between the target and the masker speech. Three experiments investigated whether speech-in-speech recognition varies across different background speech languages (English vs Dutch) for both English and Dutch targets, as well as across variation in the semantic content of the background speech (meaningful vs semantically anomalous sentences), and across variation in listener status vis-à-vis the target and masker languages (native, non-native, or unfamiliar). The results showed that the more similar the target speech is to the masker speech (e.g., same vs different language, same vs different levels of semantic content), the greater the interference on speech recognition accuracy. Moreover, the listener’s knowledge of the target and the background language modulate the size of the release from masking. These factors had an especially strong effect on masking effectiveness in highly unfavorable listening conditions. Overall this research provided evidence that that the degree of target-masker similarity plays a significant role in speech-in-speech recognition. The results also give insight into how listeners assign their resources differently depending on whether they are listening to their first or second language. PMID:22352516

  19. Auditory-Perceptual Learning Improves Speech Motor Adaptation in Children

    PubMed Central

    Shiller, Douglas M.; Rochon, Marie-Lyne

    2015-01-01

    Auditory feedback plays an important role in children’s speech development by providing the child with information about speech outcomes that is used to learn and fine-tune speech motor plans. The use of auditory feedback in speech motor learning has been extensively studied in adults by examining oral motor responses to manipulations of auditory feedback during speech production. Children are also capable of adapting speech motor patterns to perceived changes in auditory feedback, however it is not known whether their capacity for motor learning is limited by immature auditory-perceptual abilities. Here, the link between speech perceptual ability and the capacity for motor learning was explored in two groups of 5–7-year-old children who underwent a period of auditory perceptual training followed by tests of speech motor adaptation to altered auditory feedback. One group received perceptual training on a speech acoustic property relevant to the motor task while a control group received perceptual training on an irrelevant speech contrast. Learned perceptual improvements led to an enhancement in speech motor adaptation (proportional to the perceptual change) only for the experimental group. The results indicate that children’s ability to perceive relevant speech acoustic properties has a direct influence on their capacity for sensory-based speech motor adaptation. PMID:24842067

  20. Cortical activation patterns correlate with speech understanding after cochlear implantation

    PubMed Central

    Olds, Cristen; Pollonini, Luca; Abaya, Homer; Larky, Jannine; Loy, Megan; Bortfeld, Heather; Beauchamp, Michael S.; Oghalai, John S.

    2015-01-01

    Objectives Cochlear implants are a standard therapy for deafness, yet the ability of implanted patients to understand speech varies widely. To better understand this variability in outcomes, we used functional near-infrared spectroscopy (fNIRS) to image activity within regions of the auditory cortex and compare the results to behavioral measures of speech perception. Design We studied 32 deaf adults hearing through cochlear implants and 35 normal-hearing controls. We used fNIRS to measure responses within the lateral temporal lobe and the superior temporal gyrus to speech stimuli of varying intelligibility. The speech stimuli included normal speech, channelized speech (vocoded into 20 frequency bands), and scrambled speech (the 20 frequency bands were shuffled in random order). We also used environmental sounds as a control stimulus. Behavioral measures consisted of the Speech Reception Threshold, CNC words, and AzBio Sentence tests measured in quiet. Results Both control and implanted participants with good speech perception exhibited greater cortical activations to natural speech than to unintelligible speech. In contrast, implanted participants with poor speech perception had large, indistinguishable cortical activations to all stimuli. The ratio of cortical activation to normal speech to that of scrambled speech directly correlated with the CNC Words and AzBio Sentences scores. This pattern of cortical activation was not correlated with auditory threshold, age, side of implantation, or time after implantation. Turning off the implant reduced cortical activations in all implanted participants. Conclusions Together, these data indicate that the responses we measured within the lateral temporal lobe and the superior temporal gyrus correlate with behavioral measures of speech perception, demonstrating a neural basis for the variability in speech understanding outcomes after cochlear implantation. PMID:26709749

  1. Measures to Evaluate the Effects of DBS on Speech Production

    PubMed Central

    Weismer, Gary; Yunusova, Yana; Bunton, Kate

    2011-01-01

    The purpose of this paper is to review and evaluate measures of speech production that could be used to document effects of Deep Brain Stimulation (DBS) on speech performance, especially in persons with Parkinson disease (PD). A small set of evaluative criteria for these measures is presented first, followed by consideration of several speech physiology and speech acoustic measures that have been studied frequently and reported on in the literature on normal speech production, and speech production affected by neuromotor disorders (dysarthria). Each measure is reviewed and evaluated against the evaluative criteria. Embedded within this review and evaluation is a presentation of new data relating speech motions to speech intelligibility measures in speakers with PD, amyotrophic lateral sclerosis (ALS), and control speakers (CS). These data are used to support the conclusion that at the present time the slope of second formant transitions (F2 slope), an acoustic measure, is well suited to make inferences to speech motion and to predict speech intelligibility. The use of other measures should not be ruled out, however, and we encourage further development of evaluative criteria for speech measures designed to probe the effects of DBS or any treatment with potential effects on speech production and communication skills. PMID:24932066

  2. Spectral and temporal changes to speech produced in the presence of energetic and informational maskers.

    PubMed

    Cooke, Martin; Lu, Youyi

    2010-10-01

    Talkers change the way they speak in noisy conditions. For energetic maskers, speech production changes are relatively well-understood, but less is known about how informational maskers such as competing speech affect speech production. The current study examines the effect of energetic and informational maskers on speech production by talkers speaking alone or in pairs. Talkers produced speech in quiet and in backgrounds of speech-shaped noise, speech-modulated noise, and competing speech. Relative to quiet, speech output level and fundamental frequency increased and spectral tilt flattened in proportion to the energetic masking capacity of the background. In response to modulated backgrounds, talkers were able to reduce substantially the degree of temporal overlap with the noise, with greater reduction for the competing speech background. Reduction in foreground-background overlap can be expected to lead to a release from both energetic and informational masking for listeners. Passive changes in speech rate, mean pause length or pause distribution cannot explain the overlap reduction, which appears instead to result from a purposeful process of listening while speaking. Talkers appear to monitor the background and exploit upcoming pauses, a strategy which is particularly effective for backgrounds containing intelligible speech.

  3. Speech Comprehension Difficulties in Chronic Tinnitus and Its Relation to Hyperacusis

    PubMed Central

    Vielsmeier, Veronika; Kreuzer, Peter M.; Haubner, Frank; Steffens, Thomas; Semmler, Philipp R. O.; Kleinjung, Tobias; Schlee, Winfried; Langguth, Berthold; Schecklmann, Martin

    2016-01-01

    Objective: Many tinnitus patients complain about difficulties regarding speech comprehension. In spite of the high clinical relevance little is known about underlying mechanisms and predisposing factors. Here, we performed an exploratory investigation in a large sample of tinnitus patients to (1) estimate the prevalence of speech comprehension difficulties among tinnitus patients, to (2) compare subjective reports of speech comprehension difficulties with behavioral measurements in a standardized speech comprehension test and to (3) explore underlying mechanisms by analyzing the relationship between speech comprehension difficulties and peripheral hearing function (pure tone audiogram), as well as with co-morbid hyperacusis as a central auditory processing disorder. Subjects and Methods: Speech comprehension was assessed in 361 tinnitus patients presenting between 07/2012 and 08/2014 at the Interdisciplinary Tinnitus Clinic at the University of Regensburg. The assessment included standard audiological assessments (pure tone audiometry, tinnitus pitch, and loudness matching), the Goettingen sentence test (in quiet) for speech audiometric evaluation, two questions about hyperacusis, and two questions about speech comprehension in quiet and noisy environments (“How would you rate your ability to understand speech?”; “How would you rate your ability to follow a conversation when multiple people are speaking simultaneously?”). Results: Subjectively-reported speech comprehension deficits are frequent among tinnitus patients, especially in noisy environments (cocktail party situation). 74.2% of all investigated patients showed disturbed speech comprehension (indicated by values above 21.5 dB SPL in the Goettingen sentence test). Subjective speech comprehension complaints (both for general and in noisy environment) were correlated with hearing level and with audiologically-assessed speech comprehension ability. In contrast, co-morbid hyperacusis was only correlated with speech comprehension difficulties in noisy environments, but not with speech comprehension difficulties in general. Conclusion: Speech comprehension deficits are frequent among tinnitus patients. Whereas speech comprehension deficits in quiet environments are primarily due to peripheral hearing loss, speech comprehension deficits in noisy environments are related to both peripheral hearing loss and dysfunctional central auditory processing. Disturbed speech comprehension in noisy environments might be modulated by a central inhibitory deficit. In addition, attentional and cognitive aspects may play a role. PMID:28018209

  4. Speech Comprehension Difficulties in Chronic Tinnitus and Its Relation to Hyperacusis.

    PubMed

    Vielsmeier, Veronika; Kreuzer, Peter M; Haubner, Frank; Steffens, Thomas; Semmler, Philipp R O; Kleinjung, Tobias; Schlee, Winfried; Langguth, Berthold; Schecklmann, Martin

    2016-01-01

    Objective: Many tinnitus patients complain about difficulties regarding speech comprehension. In spite of the high clinical relevance little is known about underlying mechanisms and predisposing factors. Here, we performed an exploratory investigation in a large sample of tinnitus patients to (1) estimate the prevalence of speech comprehension difficulties among tinnitus patients, to (2) compare subjective reports of speech comprehension difficulties with behavioral measurements in a standardized speech comprehension test and to (3) explore underlying mechanisms by analyzing the relationship between speech comprehension difficulties and peripheral hearing function (pure tone audiogram), as well as with co-morbid hyperacusis as a central auditory processing disorder. Subjects and Methods: Speech comprehension was assessed in 361 tinnitus patients presenting between 07/2012 and 08/2014 at the Interdisciplinary Tinnitus Clinic at the University of Regensburg. The assessment included standard audiological assessments (pure tone audiometry, tinnitus pitch, and loudness matching), the Goettingen sentence test (in quiet) for speech audiometric evaluation, two questions about hyperacusis, and two questions about speech comprehension in quiet and noisy environments ("How would you rate your ability to understand speech?"; "How would you rate your ability to follow a conversation when multiple people are speaking simultaneously?"). Results: Subjectively-reported speech comprehension deficits are frequent among tinnitus patients, especially in noisy environments (cocktail party situation). 74.2% of all investigated patients showed disturbed speech comprehension (indicated by values above 21.5 dB SPL in the Goettingen sentence test). Subjective speech comprehension complaints (both for general and in noisy environment) were correlated with hearing level and with audiologically-assessed speech comprehension ability. In contrast, co-morbid hyperacusis was only correlated with speech comprehension difficulties in noisy environments, but not with speech comprehension difficulties in general. Conclusion: Speech comprehension deficits are frequent among tinnitus patients. Whereas speech comprehension deficits in quiet environments are primarily due to peripheral hearing loss, speech comprehension deficits in noisy environments are related to both peripheral hearing loss and dysfunctional central auditory processing. Disturbed speech comprehension in noisy environments might be modulated by a central inhibitory deficit. In addition, attentional and cognitive aspects may play a role.

  5. The effect of filtered speech feedback on the frequency of stuttering

    NASA Astrophysics Data System (ADS)

    Rami, Manish Krishnakant

    2000-10-01

    This study investigated the effects of filtered components of speech and whispered speech on the frequency of stuttering. It is known that choral speech, shadowing, and altered auditory feedback are the only conditions which induce fluency without any additional effort than normally required to speak on the part of people who stutter. All these conditions use speech as a second signal. This experiment examined the role of components of speech signal as delineated by the source- filter theory of speech production. Three filtered speech signals, a whispered speech signal, and a choral speech signal formed the stimuli. It was postulated that if the speech signal in whole was necessary for producing fluency in people who stutter, then all other conditions except choral speech should fail to produce fluency enhancement. If the glottal source alone was adequate in restoring fluency, then only the conditions of NAF and whispered speech should fail in promoting fluency. In the event that full filter characteristics are necessary for the fluency creating effects, then all conditions except the choral speech and whispered speech should fail to produce fluency. If any part of the filter characteristics is sufficient in yielding fluency, then only the NAF and the approximate glottal source should fail to demonstrate an increase in the amount of fluency. Twelve adults who stuttered read passages under the six conditions while receiving auditory feedback consisting of one of the six experimental conditions: (a)NAF; (b)approximate glottal source; (c)glottal source and first formant; (d)glottal source and first two formants; and (e)whispered speech. Frequencies of stuttering were obtained for each condition and submitted to descriptive and inferential statistical analysis. Statistically significant differences in means were found within the choral feedback conditions. Specifically, the choral speech, the source and first formant, source and the first two formants, and the whispered speech conditions all decreased the frequency of stuttering while the approximate glottal source did not. It is suggested that articulatory events, chiefly the encoded speech output of the vocal tract origin, afford effective cues and induces fluent speech in people who stutter.

  6. Effects of Within-Talker Variability on Speech Intelligibility in Mandarin-Speaking Adult and Pediatric Cochlear Implant Patients

    PubMed Central

    Su, Qiaotong; Galvin, John J.; Zhang, Guoping; Li, Yongxin

    2016-01-01

    Cochlear implant (CI) speech performance is typically evaluated using well-enunciated speech produced at a normal rate by a single talker. CI users often have greater difficulty with variations in speech production encountered in everyday listening. Within a single talker, speaking rate, amplitude, duration, and voice pitch information may be quite variable, depending on the production context. The coarse spectral resolution afforded by the CI limits perception of voice pitch, which is an important cue for speech prosody and for tonal languages such as Mandarin Chinese. In this study, sentence recognition from the Mandarin speech perception database was measured in adult and pediatric Mandarin-speaking CI listeners for a variety of speaking styles: voiced speech produced at slow, normal, and fast speaking rates; whispered speech; voiced emotional speech; and voiced shouted speech. Recognition of Mandarin Hearing in Noise Test sentences was also measured. Results showed that performance was significantly poorer with whispered speech relative to the other speaking styles and that performance was significantly better with slow speech than with fast or emotional speech. Results also showed that adult and pediatric performance was significantly poorer with Mandarin Hearing in Noise Test than with Mandarin speech perception sentences at the normal rate. The results suggest that adult and pediatric Mandarin-speaking CI patients are highly susceptible to whispered speech, due to the lack of lexically important voice pitch cues and perhaps other qualities associated with whispered speech. The results also suggest that test materials may contribute to differences in performance observed between adult and pediatric CI users. PMID:27363714

  7. EEG oscillations entrain their phase to high-level features of speech sound.

    PubMed

    Zoefel, Benedikt; VanRullen, Rufin

    2016-01-01

    Phase entrainment of neural oscillations, the brain's adjustment to rhythmic stimulation, is a central component in recent theories of speech comprehension: the alignment between brain oscillations and speech sound improves speech intelligibility. However, phase entrainment to everyday speech sound could also be explained by oscillations passively following the low-level periodicities (e.g., in sound amplitude and spectral content) of auditory stimulation-and not by an adjustment to the speech rhythm per se. Recently, using novel speech/noise mixture stimuli, we have shown that behavioral performance can entrain to speech sound even when high-level features (including phonetic information) are not accompanied by fluctuations in sound amplitude and spectral content. In the present study, we report that neural phase entrainment might underlie our behavioral findings. We observed phase-locking between electroencephalogram (EEG) and speech sound in response not only to original (unprocessed) speech but also to our constructed "high-level" speech/noise mixture stimuli. Phase entrainment to original speech and speech/noise sound did not differ in the degree of entrainment, but rather in the actual phase difference between EEG signal and sound. Phase entrainment was not abolished when speech/noise stimuli were presented in reverse (which disrupts semantic processing), indicating that acoustic (rather than linguistic) high-level features play a major role in the observed neural entrainment. Our results provide further evidence for phase entrainment as a potential mechanism underlying speech processing and segmentation, and for the involvement of high-level processes in the adjustment to the rhythm of speech. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. Perceived Liveliness and Speech Comprehensibility in Aphasia: The Effects of Direct Speech in Auditory Narratives

    ERIC Educational Resources Information Center

    Groenewold, Rimke; Bastiaanse, Roelien; Nickels, Lyndsey; Huiskes, Mike

    2014-01-01

    Background: Previous studies have shown that in semi-spontaneous speech, individuals with Broca's and anomic aphasia produce relatively many direct speech constructions. It has been claimed that in "healthy" communication direct speech constructions contribute to the liveliness, and indirectly to the comprehensibility, of speech.…

  9. Motor Speech Phenotypes of Frontotemporal Dementia, Primary Progressive Aphasia, and Progressive Apraxia of Speech

    ERIC Educational Resources Information Center

    Poole, Matthew L.; Brodtmann, Amy; Darby, David; Vogel, Adam P.

    2017-01-01

    Purpose: Our purpose was to create a comprehensive review of speech impairment in frontotemporal dementia (FTD), primary progressive aphasia (PPA), and progressive apraxia of speech in order to identify the most effective measures for diagnosis and monitoring, and to elucidate associations between speech and neuroimaging. Method: Speech and…

  10. Listeners Experience Linguistic Masking Release in Noise-Vocoded Speech-in-Speech Recognition

    ERIC Educational Resources Information Center

    Viswanathan, Navin; Kokkinakis, Kostas; Williams, Brittany T.

    2018-01-01

    Purpose: The purpose of this study was to evaluate whether listeners with normal hearing perceiving noise-vocoded speech-in-speech demonstrate better intelligibility of target speech when the background speech was mismatched in language (linguistic release from masking [LRM]) and/or location (spatial release from masking [SRM]) relative to the…

  11. The Role of Visual Speech Information in Supporting Perceptual Learning of Degraded Speech

    ERIC Educational Resources Information Center

    Wayne, Rachel V.; Johnsrude, Ingrid S.

    2012-01-01

    Following cochlear implantation, hearing-impaired listeners must adapt to speech as heard through their prosthesis. Visual speech information (VSI; the lip and facial movements of speech) is typically available in everyday conversation. Here, we investigate whether learning to understand a popular auditory simulation of speech as transduced by a…

  12. Inner Speech's Relationship with Overt Speech in Poststroke Aphasia

    ERIC Educational Resources Information Center

    Stark, Brielle C.; Geva, Sharon; Warburton, Elizabeth A.

    2017-01-01

    Purpose: Relatively preserved inner speech alongside poor overt speech has been documented in some persons with aphasia (PWA), but the relationship of overt speech with inner speech is still largely unclear, as few studies have directly investigated these factors. The present study investigates the relationship of relatively preserved inner speech…

  13. TEACHER'S GUIDE TO HIGH SCHOOL SPEECH.

    ERIC Educational Resources Information Center

    JENKINSON, EDWARD B., ED.

    THIS GUIDE TO HIGH SCHOOL SPEECH FOCUSES ON SPEECH AS ORAL COMPOSITION, STRESSING THE IMPORTANCE OF CLEAR THINKING AND COMMUNICATION. THE PROPOSED 1-SEMESTER BASIC COURSE IN SPEECH ATTEMPTS TO IMPROVE THE STUDENT'S ABILITY TO COMPOSE AND DELIVER SPEECHES, TO THINK AND LISTEN CRITICALLY, AND TO UNDERSTAND THE SOCIAL FUNCTION OF SPEECH. IN ADDITION…

  14. Comparison of a novel bedside portable endoscopy device with nasogastric aspiration for identifying upper gastrointestinal bleeding.

    PubMed

    Choi, Jong Hwan; Choi, Jae Hyuk; Lee, Yoo Jin; Lee, Hyung Ki; Choi, Wang Yong; Kim, Eun Soo; Park, Kyung Sik; Cho, Kwang Bum; Jang, Byoung Kuk; Chung, Woo Jin; Hwang, Jae Seok

    2014-07-07

    To compare outcomes using the novel portable endoscopy with that of nasogastric (NG) aspiration in patients with gastrointestinal bleeding. Patients who underwent NG aspiration for the evaluation of upper gastrointestinal (UGI) bleeding were eligible for the study. After NG aspiration, we performed the portable endoscopy to identify bleeding evidence in the UGI tract. Then, all patients underwent conventional esophagogastroduodenoscopy as the gold-standard test. The sensitivity, specificity, and accuracy of the portable endoscopy for confirming UGI bleeding were compared with those of NG aspiration. In total, 129 patients who had GI bleeding signs or symptoms were included in the study (age 64.46 ± 13.79, 91 males). The UGI tract (esophagus, stomach, and duodenum) was the most common site of bleeding (81, 62.8%) and the cause of bleeding was not identified in 12 patients (9.3%). Specificity for identifying UGI bleeding was higher with the portable endoscopy than NG aspiration (85.4% vs 68.8%, P = 0.008) while accuracy was comparable. The accuracy of the portable endoscopy was significantly higher than that of NG in the subgroup analysis of patients with esophageal bleeding (88.2% vs 75%, P = 0.004). Food material could be detected more readily by the portable endoscopy than NG tube aspiration (20.9% vs 9.3%, P = 0.014). No serious adverse effect was observed during the portable endoscopy. The portable endoscopy was not superior to NG aspiration for confirming UGI bleeding site. However, this novel portable endoscopy device might provide a benefit over NG aspiration in patients with esophageal bleeding.

  15. Chinese speech intelligibility and its relationship with the speech transmission index for children in elementary school classrooms.

    PubMed

    Peng, Jianxin; Yan, Nanjie; Wang, Dan

    2015-01-01

    The present study investigated Chinese speech intelligibility in 28 classrooms from nine different elementary schools in Guangzhou, China. The subjective Chinese speech intelligibility in the classrooms was evaluated with children in grades 2, 4, and 6 (7 to 12 years old). Acoustical measurements were also performed in these classrooms. Subjective Chinese speech intelligibility scores and objective speech intelligibility parameters, such as speech transmission index (STI), were obtained at each listening position for all tests. The relationship between subjective Chinese speech intelligibility scores and STI was revealed and analyzed. The effects of age on Chinese speech intelligibility scores were compared. Results indicate high correlations between subjective Chinese speech intelligibility scores and STI for grades 2, 4, and 6 children. Chinese speech intelligibility scores increase with increase of age under the same STI condition. The differences in scores among different age groups decrease as STI increases. To achieve 95% Chinese speech intelligibility scores, the STIs required for grades 2, 4, and 6 children are 0.75, 0.69, and 0.63, respectively.

  16. Portable monitoring for the diagnosis of obstructive sleep apnea.

    PubMed

    Collop, Nancy A

    2008-11-01

    The demand for expedient diagnosis of suspected obstructive sleep apnea (OSA) has increased due to improved awareness of sleep disorders. Polysomnography (PSG) is the current preferred diagnostic modality but is relatively inconvenient, expensive and inefficient. Portable monitoring has been developed and is widely used in countries outside the United States as an alternative approach. A portable monitor records fewer physiologic variables but is typically unattended and can be performed in the home. Numerous portable monitor studies have been performed over the past two to three decades. The US government and medical societies have extensively reviewed this literature several times in an attempt to determine if portable monitoring should be more broadly used for diagnosing OSA. In March 2008, the US Centers for Medicare and Medicaid Services released a statement allowing the use of portable monitoring to diagnose OSA and prescribe continuous positive airway pressure. This has potentially opened the door for more widespread use of these devices. This review will focus on the literature that has examined portable monitoring as a diagnostic tool for OSA. It is anticipated that portable monitoring as a diagnostic modality for OSA will be used more frequently in the United States following the Centers for Medicare and Medicaid Services ruling. Physicians and others considering the use of portable monitors should thoroughly understand the advantages and limitations of this technology.

  17. A causal test of the motor theory of speech perception: A case of impaired speech production and spared speech perception

    PubMed Central

    Stasenko, Alena; Bonn, Cory; Teghipco, Alex; Garcea, Frank E.; Sweet, Catherine; Dombovy, Mary; McDonough, Joyce; Mahon, Bradford Z.

    2015-01-01

    In the last decade, the debate about the causal role of the motor system in speech perception has been reignited by demonstrations that motor processes are engaged during the processing of speech sounds. However, the exact role of the motor system in auditory speech processing remains elusive. Here we evaluate which aspects of auditory speech processing are affected, and which are not, in a stroke patient with dysfunction of the speech motor system. The patient’s spontaneous speech was marked by frequent phonological/articulatory errors, and those errors were caused, at least in part, by motor-level impairments with speech production. We found that the patient showed a normal phonemic categorical boundary when discriminating two nonwords that differ by a minimal pair (e.g., ADA-AGA). However, using the same stimuli, the patient was unable to identify or label the nonword stimuli (using a button-press response). A control task showed that he could identify speech sounds by speaker gender, ruling out a general labeling impairment. These data suggest that the identification (i.e. labeling) of nonword speech sounds may involve the speech motor system, but that the perception of speech sounds (i.e., discrimination) does not require the motor system. This means that motor processes are not causally involved in perception of the speech signal, and suggest that the motor system may be used when other cues (e.g., meaning, context) are not available. PMID:25951749

  18. Affective Properties of Mothers' Speech to Infants With Hearing Impairment and Cochlear Implants

    PubMed Central

    Bergeson, Tonya R.; Xu, Huiping; Kitamura, Christine

    2015-01-01

    Purpose The affective properties of infant-directed speech influence the attention of infants with normal hearing to speech sounds. This study explored the affective quality of maternal speech to infants with hearing impairment (HI) during the 1st year after cochlear implantation as compared to speech to infants with normal hearing. Method Mothers of infants with HI and mothers of infants with normal hearing matched by age (NH-AM) or hearing experience (NH-EM) were recorded playing with their infants during 3 sessions over a 12-month period. Speech samples of 25 s were low-pass filtered, leaving intonation but not speech information intact. Sixty adults rated the stimuli along 5 scales: positive/negative affect and intention to express affection, to encourage attention, to comfort/soothe, and to direct behavior. Results Low-pass filtered speech to HI and NH-EM groups was rated as more positive, affective, and comforting compared with the such speech to the NH-AM group. Speech to infants with HI and with NH-AM was rated as more directive than speech to the NH-EM group. Mothers decreased affective qualities in speech to all infants but increased directive qualities in speech to infants with NH-EM over time. Conclusions Mothers fine-tune communicative intent in speech to their infant's developmental stage. They adjust affective qualities to infants' hearing experience rather than to chronological age but adjust directive qualities of speech to the chronological age of their infants. PMID:25679195

  19. Freedom of racist speech: Ego and expressive threats.

    PubMed

    White, Mark H; Crandall, Christian S

    2017-09-01

    Do claims of "free speech" provide cover for prejudice? We investigate whether this defense of racist or hate speech serves as a justification for prejudice. In a series of 8 studies (N = 1,624), we found that explicit racial prejudice is a reliable predictor of the "free speech defense" of racist expression. Participants endorsed free speech values for singing racists songs or posting racist comments on social media; people high in prejudice endorsed free speech more than people low in prejudice (meta-analytic r = .43). This endorsement was not principled-high levels of prejudice did not predict endorsement of free speech values when identical speech was directed at coworkers or the police. Participants low in explicit racial prejudice actively avoided endorsing free speech values in racialized conditions compared to nonracial conditions, but participants high in racial prejudice increased their endorsement of free speech values in racialized conditions. Three experiments failed to find evidence that defense of racist speech by the highly prejudiced was based in self-relevant or self-protective motives. Two experiments found evidence that the free speech argument protected participants' own freedom to express their attitudes; the defense of other's racist speech seems motivated more by threats to autonomy than threats to self-regard. These studies serve as an elaboration of the Justification-Suppression Model (Crandall & Eshleman, 2003) of prejudice expression. The justification of racist speech by endorsing fundamental political values can serve to buffer racial and hate speech from normative disapproval. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  20. Speech Entrainment Compensates for Broca's Area Damage

    PubMed Central

    Fridriksson, Julius; Basilakos, Alexandra; Hickok, Gregory; Bonilha, Leonardo; Rorden, Chris

    2015-01-01

    Speech entrainment (SE), the online mimicking of an audiovisual speech model, has been shown to increase speech fluency in patients with Broca's aphasia. However, not all individuals with aphasia benefit from SE. The purpose of this study was to identify patterns of cortical damage that predict a positive response SE's fluency-inducing effects. Forty-four chronic patients with left hemisphere stroke (15 female) were included in this study. Participants completed two tasks: 1) spontaneous speech production, and 2) audiovisual SE. Number of different words per minute was calculated as a speech output measure for each task, with the difference between SE and spontaneous speech conditions yielding a measure of fluency improvement. Voxel-wise lesion-symptom mapping (VLSM) was used to relate the number of different words per minute for spontaneous speech, SE, and SE-related improvement to patterns of brain damage in order to predict lesion locations associated with the fluency-inducing response to speech entrainment. Individuals with Broca's aphasia demonstrated a significant increase in different words per minute during speech entrainment versus spontaneous speech. A similar pattern of improvement was not seen in patients with other types of aphasia. VLSM analysis revealed damage to the inferior frontal gyrus predicted this response. Results suggest that SE exerts its fluency-inducing effects by providing a surrogate target for speech production via internal monitoring processes. Clinically, these results add further support for the use of speech entrainment to improve speech production and may help select patients for speech entrainment treatment. PMID:25989443

  1. 30 CFR Appendix I to Subpart D of... - Appendix I to Subpart D of Part 18

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... LIST OF TABLES Table No. Title 1 Portable power cable ampacities—600 volts. 2 Portable cord ampacities—600 volts. 3 Portable power cable ampacities—601 to 5,000 volts. 4 Normal diameter of round cables... diameter of three-conductor portable power cables with tolerances in inches—601 to 5,000 volts. 8 Fuse...

  2. 30 CFR Appendix I to Subpart D of... - Appendix I to Subpart D of Part 18

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... LIST OF TABLES Table No. Title 1 Portable power cable ampacities—600 volts. 2 Portable cord ampacities—600 volts. 3 Portable power cable ampacities—601 to 5,000 volts. 4 Normal diameter of round cables... diameter of three-conductor portable power cables with tolerances in inches—601 to 5,000 volts. 8 Fuse...

  3. The role of hearing ability and speech distortion in the facilitation of articulatory motor cortex.

    PubMed

    Nuttall, Helen E; Kennedy-Higgins, Daniel; Devlin, Joseph T; Adank, Patti

    2017-01-08

    Excitability of articulatory motor cortex is facilitated when listening to speech in challenging conditions. Beyond this, however, we have little knowledge of what listener-specific and speech-specific factors engage articulatory facilitation during speech perception. For example, it is unknown whether speech motor activity is independent or dependent on the form of distortion in the speech signal. It is also unknown if speech motor facilitation is moderated by hearing ability. We investigated these questions in two experiments. We applied transcranial magnetic stimulation (TMS) to the lip area of primary motor cortex (M1) in young, normally hearing participants to test if lip M1 is sensitive to the quality (Experiment 1) or quantity (Experiment 2) of distortion in the speech signal, and if lip M1 facilitation relates to the hearing ability of the listener. Experiment 1 found that lip motor evoked potentials (MEPs) were larger during perception of motor-distorted speech that had been produced using a tongue depressor, and during perception of speech presented in background noise, relative to natural speech in quiet. Experiment 2 did not find evidence of motor system facilitation when speech was presented in noise at signal-to-noise ratios where speech intelligibility was at 50% or 75%, which were significantly less severe noise levels than used in Experiment 1. However, there was a significant interaction between noise condition and hearing ability, which indicated that when speech stimuli were correctly classified at 50%, speech motor facilitation was observed in individuals with better hearing, whereas individuals with relatively worse but still normal hearing showed more activation during perception of clear speech. These findings indicate that the motor system may be sensitive to the quantity, but not quality, of degradation in the speech signal. Data support the notion that motor cortex complements auditory cortex during speech perception, and point to a role for the motor cortex in compensating for differences in hearing ability. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Portable TXRF Spectrometer with 10{sup -11}g Detection Limit and Portable XRF Spectromicroscope with Sub-mm Spatial Resolution

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kunimura, Shinsuke; Hatakeyama, So; Sasaki, Nobuharu

    A portable total reflection X-ray fluorescence (TXRF) spectrometer that we have developed is applied to trace elemental analysis of water solutions. Although a 5 W X-ray tube is used in the portable TXRF spectrometer, detection limits of several ppb are achieved for 3d transition metal elements and trace elements in a leaching solution of soils, a leaching solution of solder, and alcoholic beverages are detected. Portable X-ray fluorescence (XRF) spectromicroscopes with a 1 W X-ray tube and an 8 W X-ray tube are also presented. Using the portable XRF spectromicroscope with the 1 W X-ray tube, 93 ppm of Crmore » is detected with an about 700 {mu}m spatial resolution. Spatially resolved elemental analysis of a mug painted with blue, red, green, and white is performed using the two portable spectromicroscopes, and the difference in elemental composition at each paint is detected.« less

  5. Development and Applications of Portable Gas Chromatography-Mass Spectrometry for Emergency Responders, the Military, and Law-Enforcement Organizations.

    PubMed

    Leary, Pauline E; Dobson, Gareth S; Reffner, John A

    2016-05-01

    Portable gas chromatography-mass spectrometry (GC-MS) systems are being deployed for field use, and are designed with this goal in mind. Performance characteristics of instruments that are successful in the field are different from those of equivalent technologies that are successful in a laboratory setting. These field-portable systems are extending the capabilities of the field user, providing investigative leads and confirmatory identifications in real time. Many different types of users benefit from the availability of this technology including emergency responders, the military, and law-enforcement organizations. This manuscript describes performance characteristics that are important for field-portable instruments, especially field-portable GC-MS systems, and demonstrates the value of this equipment to the disciplines of explosives investigations, fire investigations, and counterfeit-drug detection. This paper describes the current state of portable GC-MS technology, including a review of the development of portable GC-MS, as well as a demonstration of the value of this capability using different examples. © The Author(s) 2016.

  6. How visual timing and form information affect speech and non-speech processing.

    PubMed

    Kim, Jeesun; Davis, Chris

    2014-10-01

    Auditory speech processing is facilitated when the talker's face/head movements are seen. This effect is typically explained in terms of visual speech providing form and/or timing information. We determined the effect of both types of information on a speech/non-speech task (non-speech stimuli were spectrally rotated speech). All stimuli were presented paired with the talker's static or moving face. Two types of moving face stimuli were used: full-face versions (both spoken form and timing information available) and modified face versions (only timing information provided by peri-oral motion available). The results showed that the peri-oral timing information facilitated response time for speech and non-speech stimuli compared to a static face. An additional facilitatory effect was found for full-face versions compared to the timing condition; this effect only occurred for speech stimuli. We propose the timing effect was due to cross-modal phase resetting; the form effect to cross-modal priming. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. System and method for characterizing voiced excitations of speech and acoustic signals, removing acoustic noise from speech, and synthesizing speech

    DOEpatents

    Burnett, Greg C [Livermore, CA; Holzrichter, John F [Berkeley, CA; Ng, Lawrence C [Danville, CA

    2006-08-08

    The present invention is a system and method for characterizing human (or animate) speech voiced excitation functions and acoustic signals, for removing unwanted acoustic noise which often occurs when a speaker uses a microphone in common environments, and for synthesizing personalized or modified human (or other animate) speech upon command from a controller. A low power EM sensor is used to detect the motions of windpipe tissues in the glottal region of the human speech system before, during, and after voiced speech is produced by a user. From these tissue motion measurements, a voiced excitation function can be derived. Further, the excitation function provides speech production information to enhance noise removal from human speech and it enables accurate transfer functions of speech to be obtained. Previously stored excitation and transfer functions can be used for synthesizing personalized or modified human speech. Configurations of EM sensor and acoustic microphone systems are described to enhance noise cancellation and to enable multiple articulator measurements.

  8. System and method for characterizing voiced excitations of speech and acoustic signals, removing acoustic noise from speech, and synthesizing speech

    DOEpatents

    Burnett, Greg C.; Holzrichter, John F.; Ng, Lawrence C.

    2004-03-23

    The present invention is a system and method for characterizing human (or animate) speech voiced excitation functions and acoustic signals, for removing unwanted acoustic noise which often occurs when a speaker uses a microphone in common environments, and for synthesizing personalized or modified human (or other animate) speech upon command from a controller. A low power EM sensor is used to detect the motions of windpipe tissues in the glottal region of the human speech system before, during, and after voiced speech is produced by a user. From these tissue motion measurements, a voiced excitation function can be derived. Further, the excitation function provides speech production information to enhance noise removal from human speech and it enables accurate transfer functions of speech to be obtained. Previously stored excitation and transfer functions can be used for synthesizing personalized or modified human speech. Configurations of EM sensor and acoustic microphone systems are described to enhance noise cancellation and to enable multiple articulator measurements.

  9. System and method for characterizing voiced excitations of speech and acoustic signals, removing acoustic noise from speech, and synthesizing speech

    DOEpatents

    Burnett, Greg C.; Holzrichter, John F.; Ng, Lawrence C.

    2006-02-14

    The present invention is a system and method for characterizing human (or animate) speech voiced excitation functions and acoustic signals, for removing unwanted acoustic noise which often occurs when a speaker uses a microphone in common environments, and for synthesizing personalized or modified human (or other animate) speech upon command from a controller. A low power EM sensor is used to detect the motions of windpipe tissues in the glottal region of the human speech system before, during, and after voiced speech is produced by a user. From these tissue motion measurements, a voiced excitation function can be derived. Further, the excitation function provides speech production information to enhance noise removal from human speech and it enables accurate transfer functions of speech to be obtained. Previously stored excitation and transfer functions can be used for synthesizing personalized or modified human speech. Configurations of EM sensor and acoustic microphone systems are described to enhance noise cancellation and to enable multiple articulator measurements.

  10. Children perceive speech onsets by ear and eye*

    PubMed Central

    JERGER, SUSAN; DAMIAN, MARKUS F.; TYE-MURRAY, NANCY; ABDI, HERVÉ

    2016-01-01

    Adults use vision to perceive low-fidelity speech; yet how children acquire this ability is not well understood. The literature indicates that children show reduced sensitivity to visual speech from kindergarten to adolescence. We hypothesized that this pattern reflects the effects of complex tasks and a growth period with harder-to-utilize cognitive resources, not lack of sensitivity. We investigated sensitivity to visual speech in children via the phonological priming produced by low-fidelity (non-intact onset) auditory speech presented audiovisually (see dynamic face articulate consonant/rhyme b/ag; hear non-intact onset/rhyme: −b/ag) vs. auditorily (see still face; hear exactly same auditory input). Audiovisual speech produced greater priming from four to fourteen years, indicating that visual speech filled in the non-intact auditory onsets. The influence of visual speech depended uniquely on phonology and speechreading. Children – like adults – perceive speech onsets multimodally. Findings are critical for incorporating visual speech into developmental theories of speech perception. PMID:26752548

  11. Impairments of speech fluency in Lewy body spectrum disorder.

    PubMed

    Ash, Sharon; McMillan, Corey; Gross, Rachel G; Cook, Philip; Gunawardena, Delani; Morgan, Brianna; Boller, Ashley; Siderowf, Andrew; Grossman, Murray

    2012-03-01

    Few studies have examined connected speech in demented and non-demented patients with Parkinson's disease (PD). We assessed the speech production of 35 patients with Lewy body spectrum disorder (LBSD), including non-demented PD patients, patients with PD dementia (PDD), and patients with dementia with Lewy bodies (DLB), in a semi-structured narrative speech sample in order to characterize impairments of speech fluency and to determine the factors contributing to reduced speech fluency in these patients. Both demented and non-demented PD patients exhibited reduced speech fluency, characterized by reduced overall speech rate and long pauses between sentences. Reduced speech rate in LBSD correlated with measures of between-utterance pauses, executive functioning, and grammatical comprehension. Regression analyses related non-fluent speech, grammatical difficulty, and executive difficulty to atrophy in frontal brain regions. These findings indicate that multiple factors contribute to slowed speech in LBSD, and this is mediated in part by disease in frontal brain regions. Copyright © 2011 Elsevier Inc. All rights reserved.

  12. Speech processing using conditional observable maximum likelihood continuity mapping

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hogden, John; Nix, David

    A computer implemented method enables the recognition of speech and speech characteristics. Parameters are initialized of first probability density functions that map between the symbols in the vocabulary of one or more sequences of speech codes that represent speech sounds and a continuity map. Parameters are also initialized of second probability density functions that map between the elements in the vocabulary of one or more desired sequences of speech transcription symbols and the continuity map. The parameters of the probability density functions are then trained to maximize the probabilities of the desired sequences of speech-transcription symbols. A new sequence ofmore » speech codes is then input to the continuity map having the trained first and second probability function parameters. A smooth path is identified on the continuity map that has the maximum probability for the new sequence of speech codes. The probability of each speech transcription symbol for each input speech code can then be output.« less

  13. Walking the talk--speech activates the leg motor cortex.

    PubMed

    Liuzzi, Gianpiero; Ellger, Tanja; Flöel, Agnes; Breitenstein, Caterina; Jansen, Andreas; Knecht, Stefan

    2008-09-01

    Speech may have evolved from earlier modes of communication based on gestures. Consistent with such a motor theory of speech, cortical orofacial and hand motor areas are activated by both speech production and speech perception. However, the extent of speech-related activation of the motor cortex remains unclear. Therefore, we examined if reading and listening to continuous prose also activates non-brachiofacial motor representations like the leg motor cortex. We found corticospinal excitability of bilateral leg muscle representations to be enhanced by speech production and silent reading. Control experiments showed that speech production yielded stronger facilitation of the leg motor system than non-verbal tongue-mouth mobilization and silent reading more than a visuo-attentional task thus indicating speech-specificity of the effect. In the frame of the motor theory of speech this finding suggests that the system of gestural communication, from which speech may have evolved, is not confined to the hand but includes gestural movements of other body parts as well.

  14. Religious Speech in the Military: Freedoms and Limitations

    DTIC Science & Technology

    2011-01-01

    abridging the freedom of speech .” Speech is construed broadly and includes both oral and written speech, as well as expressive conduct and displays when...intended to convey a message that is likely to be understood.7 Religious speech is certainly included. As a bedrock constitutional right, freedom of speech has...to good order and discipline or of a nature to bring discredit upon the armed forces)—the First Amendment’s freedom of speech will not provide them

  15. Dog-directed speech: why do we use it and do dogs pay attention to it?

    PubMed Central

    Ben-Aderet, Tobey; Gallego-Abenza, Mario

    2017-01-01

    Pet-directed speech is strikingly similar to infant-directed speech, a peculiar speaking pattern with higher pitch and slower tempo known to engage infants' attention and promote language learning. Here, we report the first investigation of potential factors modulating the use of dog-directed speech, as well as its immediate impact on dogs' behaviour. We recorded adult participants speaking in front of pictures of puppies, adult and old dogs, and analysed the quality of their speech. We then performed playback experiments to assess dogs' reaction to dog-directed speech compared with normal speech. We found that human speakers used dog-directed speech with dogs of all ages and that the acoustic structure of dog-directed speech was mostly independent of dog age, except for sound pitch which was relatively higher when communicating with puppies. Playback demonstrated that, in the absence of other non-auditory cues, puppies were highly reactive to dog-directed speech, and that the pitch was a key factor modulating their behaviour, suggesting that this specific speech register has a functional value in young dogs. Conversely, older dogs did not react differentially to dog-directed speech compared with normal speech. The fact that speakers continue to use dog-directed with older dogs therefore suggests that this speech pattern may mainly be a spontaneous attempt to facilitate interactions with non-verbal listeners. PMID:28077769

  16. The prevalence of stuttering, voice, and speech-sound disorders in primary school students in Australia.

    PubMed

    McKinnon, David H; McLeod, Sharynne; Reilly, Sheena

    2007-01-01

    The aims of this study were threefold: to report teachers' estimates of the prevalence of speech disorders (specifically, stuttering, voice, and speech-sound disorders); to consider correspondence between the prevalence of speech disorders and gender, grade level, and socioeconomic status; and to describe the level of support provided to schoolchildren with speech disorders. Students with speech disorders were identified from 10,425 students in Australia using a 4-stage process: training in the data collection process, teacher identification, confirmation by a speech-language pathologist, and consultation with district special needs advisors. The prevalence of students with speech disorders was estimated; specifically, 0.33% of students were identified as stuttering, 0.12% as having a voice disorder, and 1.06% as having a speech-sound disorder. There was a higher prevalence of speech disorders in males than in females. As grade level increased, the prevalence of speech disorders decreased. There was no significant difference in the pattern of prevalence across the three speech disorders and four socioeconomic groups; however, students who were identified with a speech disorder were more likely to be in the higher socioeconomic groups. Finally, there was a difference between the perceived and actual level of support that was provided to these students. These prevalence figures are lower than those using initial identification by speech-language pathologists and similar to those using parent report.

  17. Role of contextual cues on the perception of spectrally reduced interrupted speech.

    PubMed

    Patro, Chhayakanta; Mendel, Lisa Lucks

    2016-08-01

    Understanding speech within an auditory scene is constantly challenged by interfering noise in suboptimal listening environments when noise hinders the continuity of the speech stream. In such instances, a typical auditory-cognitive system perceptually integrates available speech information and "fills in" missing information in the light of semantic context. However, individuals with cochlear implants (CIs) find it difficult and effortful to understand interrupted speech compared to their normal hearing counterparts. This inefficiency in perceptual integration of speech could be attributed to further degradations in the spectral-temporal domain imposed by CIs making it difficult to utilize the contextual evidence effectively. To address these issues, 20 normal hearing adults listened to speech that was spectrally reduced and spectrally reduced interrupted in a manner similar to CI processing. The Revised Speech Perception in Noise test, which includes contextually rich and contextually poor sentences, was used to evaluate the influence of semantic context on speech perception. Results indicated that listeners benefited more from semantic context when they listened to spectrally reduced speech alone. For the spectrally reduced interrupted speech, contextual information was not as helpful under significant spectral reductions, but became beneficial as the spectral resolution improved. These results suggest top-down processing facilitates speech perception up to a point, and it fails to facilitate speech understanding when the speech signals are significantly degraded.

  18. Dog-directed speech: why do we use it and do dogs pay attention to it?

    PubMed

    Ben-Aderet, Tobey; Gallego-Abenza, Mario; Reby, David; Mathevon, Nicolas

    2017-01-11

    Pet-directed speech is strikingly similar to infant-directed speech, a peculiar speaking pattern with higher pitch and slower tempo known to engage infants' attention and promote language learning. Here, we report the first investigation of potential factors modulating the use of dog-directed speech, as well as its immediate impact on dogs' behaviour. We recorded adult participants speaking in front of pictures of puppies, adult and old dogs, and analysed the quality of their speech. We then performed playback experiments to assess dogs' reaction to dog-directed speech compared with normal speech. We found that human speakers used dog-directed speech with dogs of all ages and that the acoustic structure of dog-directed speech was mostly independent of dog age, except for sound pitch which was relatively higher when communicating with puppies. Playback demonstrated that, in the absence of other non-auditory cues, puppies were highly reactive to dog-directed speech, and that the pitch was a key factor modulating their behaviour, suggesting that this specific speech register has a functional value in young dogs. Conversely, older dogs did not react differentially to dog-directed speech compared with normal speech. The fact that speakers continue to use dog-directed with older dogs therefore suggests that this speech pattern may mainly be a spontaneous attempt to facilitate interactions with non-verbal listeners. © 2017 The Author(s).

  19. The cortical representation of the speech envelope is earlier for audiovisual speech than audio speech.

    PubMed

    Crosse, Michael J; Lalor, Edmund C

    2014-04-01

    Visual speech can greatly enhance a listener's comprehension of auditory speech when they are presented simultaneously. Efforts to determine the neural underpinnings of this phenomenon have been hampered by the limited temporal resolution of hemodynamic imaging and the fact that EEG and magnetoencephalographic data are usually analyzed in response to simple, discrete stimuli. Recent research has shown that neuronal activity in human auditory cortex tracks the envelope of natural speech. Here, we exploit this finding by estimating a linear forward-mapping between the speech envelope and EEG data and show that the latency at which the envelope of natural speech is represented in cortex is shortened by >10 ms when continuous audiovisual speech is presented compared with audio-only speech. In addition, we use a reverse-mapping approach to reconstruct an estimate of the speech stimulus from the EEG data and, by comparing the bimodal estimate with the sum of the unimodal estimates, find no evidence of any nonlinear additive effects in the audiovisual speech condition. These findings point to an underlying mechanism that could account for enhanced comprehension during audiovisual speech. Specifically, we hypothesize that low-level acoustic features that are temporally coherent with the preceding visual stream may be synthesized into a speech object at an earlier latency, which may provide an extended period of low-level processing before extraction of semantic information.

  20. Satellite sound broadcasting system, portable reception

    NASA Technical Reports Server (NTRS)

    Golshan, Nasser; Vaisnys, Arvydas

    1990-01-01

    Studies are underway at JPL in the emerging area of Satellite Sound Broadcast Service (SSBS) for direct reception by low cost portable, semi portable, mobile and fixed radio receivers. This paper addresses the portable reception of digital broadcasting of monophonic audio with source material band limited to 5 KHz (source audio comparable to commercial AM broadcasting). The proposed system provides transmission robustness, uniformity of performance over the coverage area and excellent frequency reuse. Propagation problems associated with indoor portable reception are considered in detail and innovative antenna concepts are suggested to mitigate these problems. It is shown that, with the marriage of proper technologies a single medium power satellite can provide substantial direct satellite audio broadcast capability to CONUS in UHF or L Bands, for high quality portable indoor reception by low cost radio receivers.

  1. 76 FR 69737 - Information Collections Being Reviewed by the Federal Communications Commission for Extension...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-09

    ...: Telecommunications Relay Services and Speech-to-Speech Services for Individuals with Hearing and Speech Disabilities... Services and Speech-to-Speech Services for Individuals with Hearing and Speech Disabilities; Americans with Disabilities Act of 1990, CC Docket No. 98-67, CG Docket No. 10-123, Second Report and Order, Order on...

  2. Visual Context Enhanced: The Joint Contribution of Iconic Gestures and Visible Speech to Degraded Speech Comprehension

    ERIC Educational Resources Information Center

    Drijvers, Linda; Ozyurek, Asli

    2017-01-01

    Purpose: This study investigated whether and to what extent iconic co-speech gestures contribute to information from visible speech to enhance degraded speech comprehension at different levels of noise-vocoding. Previous studies of the contributions of these 2 visual articulators to speech comprehension have only been performed separately. Method:…

  3. Compressed Speech: Potential Application for Air Force Technical Training. Final Report, August 73-November 73.

    ERIC Educational Resources Information Center

    Dailey, K. Anne

    Time-compressed speech (also called compressed speech, speeded speech, or accelerated speech) is an extension of the normal recording procedure for reproducing the spoken word. Compressed speech can be used to achieve dramatic reductions in listening time without significant loss in comprehension. The implications of such temporal reductions in…

  4. Speech Perception and Short-Term Memory Deficits in Persistent Developmental Speech Disorder

    ERIC Educational Resources Information Center

    Kenney, Mary Kay; Barac-Cikoja, Dragana; Finnegan, Kimberly; Jeffries, Neal; Ludlow, Christy L.

    2006-01-01

    Children with developmental speech disorders may have additional deficits in speech perception and/or short-term memory. To determine whether these are only transient developmental delays that can accompany the disorder in childhood or persist as part of the speech disorder, adults with a persistent familial speech disorder were tested on speech…

  5. Poor Speech Perception Is Not a Core Deficit of Childhood Apraxia of Speech: Preliminary Findings

    ERIC Educational Resources Information Center

    Zuk, Jennifer; Iuzzini-Seigel, Jenya; Cabbage, Kathryn; Green, Jordan R.; Hogan, Tiffany P.

    2018-01-01

    Purpose: Childhood apraxia of speech (CAS) is hypothesized to arise from deficits in speech motor planning and programming, but the influence of abnormal speech perception in CAS on these processes is debated. This study examined speech perception abilities among children with CAS with and without language impairment compared to those with…

  6. Towards large-scale data analysis: challenges in the design of portable systems and use of Cloud computing.

    PubMed

    Diaz, Javier; Arrizabalaga, Saioa; Bustamante, Paul; Mesa, Iker; Añorga, Javier; Goya, Jon

    2013-01-01

    Portable systems and global communications open a broad spectrum for new health applications. In the framework of electrophysiological applications, several challenges are faced when developing portable systems embedded in Cloud computing services. In order to facilitate new developers in this area based on our experience, five areas of interest are presented in this paper where strategies can be applied for improving the performance of portable systems: transducer and conditioning, processing, wireless communications, battery and power management. Likewise, for Cloud services, scalability, portability, privacy and security guidelines have been highlighted.

  7. Embedded Data Processor and Portable Computer Technology testbeds

    NASA Technical Reports Server (NTRS)

    Alena, Richard; Liu, Yuan-Kwei; Goforth, Andre; Fernquist, Alan R.

    1993-01-01

    Attention is given to current activities in the Embedded Data Processor and Portable Computer Technology testbed configurations that are part of the Advanced Data Systems Architectures Testbed at the Information Sciences Division at NASA Ames Research Center. The Embedded Data Processor Testbed evaluates advanced microprocessors for potential use in mission and payload applications within the Space Station Freedom Program. The Portable Computer Technology (PCT) Testbed integrates and demonstrates advanced portable computing devices and data system architectures. The PCT Testbed uses both commercial and custom-developed devices to demonstrate the feasibility of functional expansion and networking for portable computers in flight missions.

  8. 46 CFR 162.028-5 - Independent laboratories: Listing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Extinguishers, Fire, Portable, Marine Type... or tests of portable fire extinguishers: (a) For dry chemical, CO2, water and foam type portable fire...

  9. 46 CFR 162.028-5 - Independent laboratories: Listing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Extinguishers, Fire, Portable, Marine Type... or tests of portable fire extinguishers: (a) For dry chemical, CO2, water and foam type portable fire...

  10. 46 CFR 162.028-5 - Independent laboratories: Listing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Extinguishers, Fire, Portable, Marine Type... or tests of portable fire extinguishers: (a) For dry chemical, CO2, water and foam type portable fire...

  11. 46 CFR 162.028-5 - Independent laboratories: Listing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Extinguishers, Fire, Portable, Marine Type... or tests of portable fire extinguishers: (a) For dry chemical, CO2, water and foam type portable fire...

  12. 46 CFR 162.028-5 - Independent laboratories: Listing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Extinguishers, Fire, Portable, Marine Type... or tests of portable fire extinguishers: (a) For dry chemical, CO2, water and foam type portable fire...

  13. Neural tracking of attended versus ignored speech is differentially affected by hearing loss.

    PubMed

    Petersen, Eline Borch; Wöstmann, Malte; Obleser, Jonas; Lunner, Thomas

    2017-01-01

    Hearing loss manifests as a reduced ability to understand speech, particularly in multitalker situations. In these situations, younger normal-hearing listeners' brains are known to track attended speech through phase-locking of neural activity to the slow-varying envelope of the speech. This study investigates how hearing loss, compensated by hearing aids, affects the neural tracking of the speech-onset envelope in elderly participants with varying degree of hearing loss (n = 27, 62-86 yr; hearing thresholds 11-73 dB hearing level). In an active listening task, a to-be-attended audiobook (signal) was presented either in quiet or against a competing to-be-ignored audiobook (noise) presented at three individualized signal-to-noise ratios (SNRs). The neural tracking of the to-be-attended and to-be-ignored speech was quantified through the cross-correlation of the electroencephalogram (EEG) and the temporal envelope of speech. We primarily investigated the effects of hearing loss and SNR on the neural envelope tracking. First, we found that elderly hearing-impaired listeners' neural responses reliably track the envelope of to-be-attended speech more than to-be-ignored speech. Second, hearing loss relates to the neural tracking of to-be-ignored speech, resulting in a weaker differential neural tracking of to-be-attended vs. to-be-ignored speech in listeners with worse hearing. Third, neural tracking of to-be-attended speech increased with decreasing background noise. Critically, the beneficial effect of reduced noise on neural speech tracking decreased with stronger hearing loss. In sum, our results show that a common sensorineural processing deficit, i.e., hearing loss, interacts with central attention mechanisms and reduces the differential tracking of attended and ignored speech. The present study investigates the effect of hearing loss in older listeners on the neural tracking of competing speech. Interestingly, we observed that whereas internal degradation (hearing loss) relates to the neural tracking of ignored speech, external sound degradation (ratio between attended and ignored speech; signal-to-noise ratio) relates to tracking of attended speech. This provides the first evidence for hearing loss affecting the ability to neurally track speech. Copyright © 2017 the American Physiological Society.

  14. Asymmetric Dynamic Attunement of Speech and Gestures in the Construction of Children's Understanding.

    PubMed

    De Jonge-Hoekstra, Lisette; Van der Steen, Steffie; Van Geert, Paul; Cox, Ralf F A

    2016-01-01

    As children learn they use their speech to express words and their hands to gesture. This study investigates the interplay between real-time gestures and speech as children construct cognitive understanding during a hands-on science task. 12 children (M = 6, F = 6) from Kindergarten (n = 5) and first grade (n = 7) participated in this study. Each verbal utterance and gesture during the task were coded, on a complexity scale derived from dynamic skill theory. To explore the interplay between speech and gestures, we applied a cross recurrence quantification analysis (CRQA) to the two coupled time series of the skill levels of verbalizations and gestures. The analysis focused on (1) the temporal relation between gestures and speech, (2) the relative strength and direction of the interaction between gestures and speech, (3) the relative strength and direction between gestures and speech for different levels of understanding, and (4) relations between CRQA measures and other child characteristics. The results show that older and younger children differ in the (temporal) asymmetry in the gestures-speech interaction. For younger children, the balance leans more toward gestures leading speech in time, while the balance leans more toward speech leading gestures for older children. Secondly, at the group level, speech attracts gestures in a more dynamically stable fashion than vice versa, and this asymmetry in gestures and speech extends to lower and higher understanding levels. Yet, for older children, the mutual coupling between gestures and speech is more dynamically stable regarding the higher understanding levels. Gestures and speech are more synchronized in time as children are older. A higher score on schools' language tests is related to speech attracting gestures more rigidly and more asymmetry between gestures and speech, only for the less difficult understanding levels. A higher score on math or past science tasks is related to less asymmetry between gestures and speech. The picture that emerges from our analyses suggests that the relation between gestures, speech and cognition is more complex than previously thought. We suggest that temporal differences and asymmetry in influence between gestures and speech arise from simultaneous coordination of synergies.

  15. Short-term effect of short, intensive speech therapy on articulation and resonance in Ugandan patients with cleft (lip and) palate.

    PubMed

    Luyten, A; Bettens, K; D'haeseleer, E; Hodges, A; Galiwango, G; Vermeersch, H; Van Lierde, K

    2016-01-01

    The purpose of the current study was to assess the short-term effectiveness of short and intensive speech therapy provided to patients with cleft (lip and) palate (C(L)P) in terms of articulation and resonance. Five Ugandan patients (age: 7.3-19.6 years) with non-syndromic C(L)P received six hours of individualized speech therapy in three to four days. Speech therapy focused on correct phonetic placement and contrasts between oral and nasal airflow and resonance. Speech evaluations performed before and immediately after speech therapy, including perceptual and instrumental assessment techniques, were compared. Post-therapy, improvement of speech was noted for most of the patients, although to varying degrees. Clinically relevant progress of objective nasalance values and/or articulation was obtained in four patients. Overall, two patients showed normal speech intelligibility, while three patients required additional speech therapy. These preliminary short-term results demonstrate that short and intensive speech therapy can be effective for patients with C(L)P in countries with limited access to speech-language therapy. However, further research is needed on the long-term effectiveness and the advantages of applying this treatment protocol in countries with good access to speech therapy. The reader will be able to (1) list the challenges in resource poor-countries to achieve access to speech-language therapy services, (2) describe when the application of speech therapy is appropriate in patients with C(L)P, (3) describe the speech therapy that can be applied to reduce compensatory articulation and resonance disorders in patients with C(L)P, and (4) list the (possible) advantages of short, intensive speech therapy for both resource-poor and developed countries. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Systematic studies of modified vocalization: the effect of speech rate on speech production measures during metronome-paced speech in persons who stutter.

    PubMed

    Davidow, Jason H

    2014-01-01

    Metronome-paced speech results in the elimination, or substantial reduction, of stuttering moments. The cause of fluency during this fluency-inducing condition is unknown. Several investigations have reported changes in speech pattern characteristics from a control condition to a metronome-paced speech condition, but failure to control speech rate between conditions limits our ability to determine if the changes were necessary for fluency. This study examined the effect of speech rate on several speech production variables during one-syllable-per-beat metronomic speech in order to determine changes that may be important for fluency during this fluency-inducing condition. Thirteen persons who stutter (PWS), aged 18-62 years, completed a series of speaking tasks. Several speech production variables were compared between conditions produced at different metronome beat rates, and between a control condition and a metronome-paced speech condition produced at a rate equal to the control condition. Vowel duration, voice onset time, pressure rise time and phonated intervals were significantly impacted by metronome beat rate. Voice onset time and the percentage of short (30-100 ms) phonated intervals significantly decreased from the control condition to the equivalent rate metronome-paced speech condition. A reduction in the percentage of short phonated intervals may be important for fluency during syllable-based metronome-paced speech for PWS. Future studies should continue examining the necessity of this reduction. In addition, speech rate must be controlled in future fluency-inducing condition studies, including neuroimaging investigations, in order for this research to make a substantial contribution to finding the fluency-inducing mechanism of fluency-inducing conditions. © 2013 Royal College of Speech and Language Therapists.

  17. Intensive treatment of speech disorders in robin sequence: a case report.

    PubMed

    Pinto, Maria Daniela Borro; Pegoraro-Krook, Maria Inês; Andrade, Laura Katarine Félix de; Correa, Ana Paula Carvalho; Rosa-Lugo, Linda Iris; Dutka, Jeniffer de Cássia Rillo

    2017-10-23

    To describe the speech of a patient with Pierre Robin Sequence (PRS) and severe speech disorders before and after participating in an Intensive Speech Therapy Program (ISTP). The ISTP consisted of two daily sessions of therapy over a 36-week period, resulting in a total of 360 therapy sessions. The sessions included the phases of establishment, generalization, and maintenance. A combination of strategies, such as modified contrast therapy and speech sound perception training, were used to elicit adequate place of articulation. The ISTP addressed correction of place of production of oral consonants and maximization of movement of the pharyngeal walls with a speech bulb reduction program. Therapy targets were addressed at the phonetic level with a gradual increase in the complexity of the productions hierarchically (e.g., syllables, words, phrases, conversation) while simultaneously addressing the velopharyngeal hypodynamism with speech bulb reductions. Re-evaluation after the ISTP revealed normal speech resonance and articulation with the speech bulb. Nasoendoscopic assessment indicated consistent velopharyngeal closure for all oral sounds with the speech bulb in place. Intensive speech therapy, combined with the use of the speech bulb, yielded positive outcomes in the rehabilitation of a clinical case with severe speech disorders associated with velopharyngeal dysfunction in Pierre Robin Sequence.

  18. Speech Inconsistency in Children With Childhood Apraxia of Speech, Language Impairment, and Speech Delay: Depends on the Stimuli.

    PubMed

    Iuzzini-Seigel, Jenya; Hogan, Tiffany P; Green, Jordan R

    2017-05-24

    The current research sought to determine (a) if speech inconsistency is a core feature of childhood apraxia of speech (CAS) or if it is driven by comorbid language impairment that affects a large subset of children with CAS and (b) if speech inconsistency is a sensitive and specific diagnostic marker that can differentiate between CAS and speech delay. Participants included 48 children ranging between 4;7 to 17;8 (years;months) with CAS (n = 10), CAS + language impairment (n = 10), speech delay (n = 10), language impairment (n = 9), or typical development (n = 9). Speech inconsistency was assessed at phonemic and token-to-token levels using a variety of stimuli. Children with CAS and CAS + language impairment performed equivalently on all inconsistency assessments. Children with language impairment evidenced high levels of speech inconsistency on the phrase "buy Bobby a puppy." Token-to-token inconsistency of monosyllabic words and the phrase "buy Bobby a puppy" was sensitive and specific in differentiating children with CAS and speech delay, whereas inconsistency calculated on other stimuli (e.g., multisyllabic words) was less efficacious in differentiating between these disorders. Speech inconsistency is a core feature of CAS and is efficacious in differentiating between children with CAS and speech delay; however, sensitivity and specificity are stimuli dependent.

  19. A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: III. Theoretical Coherence of the Pause Marker with Speech Processing Deficits in Childhood Apraxia of Speech.

    PubMed

    Shriberg, Lawrence D; Strand, Edythe A; Fourakis, Marios; Jakielski, Kathy J; Hall, Sheryl D; Karlsson, Heather B; Mabie, Heather L; McSweeny, Jane L; Tilkens, Christie M; Wilson, David L

    2017-04-14

    Previous articles in this supplement described rationale for and development of the pause marker (PM), a diagnostic marker of childhood apraxia of speech (CAS), and studies supporting its validity and reliability. The present article assesses the theoretical coherence of the PM with speech processing deficits in CAS. PM and other scores were obtained for 264 participants in 6 groups: CAS in idiopathic, neurogenetic, and complex neurodevelopmental disorders; adult-onset apraxia of speech (AAS) consequent to stroke and primary progressive apraxia of speech; and idiopathic speech delay. Participants with CAS and AAS had significantly lower scores than typically speaking reference participants and speech delay controls on measures posited to assess representational and transcoding processes. Representational deficits differed between CAS and AAS groups, with support for both underspecified linguistic representations and memory/access deficits in CAS, but for only the latter in AAS. CAS-AAS similarities in the age-sex standardized percentages of occurrence of the most frequent type of inappropriate pauses (abrupt) and significant differences in the standardized occurrence of appropriate pauses were consistent with speech processing findings. Results support the hypotheses of core representational and transcoding speech processing deficits in CAS and theoretical coherence of the PM's pause-speech elements with these deficits.

  20. Cortical Integration of Audio-Visual Information

    PubMed Central

    Vander Wyk, Brent C.; Ramsay, Gordon J.; Hudac, Caitlin M.; Jones, Warren; Lin, David; Klin, Ami; Lee, Su Mei; Pelphrey, Kevin A.

    2013-01-01

    We investigated the neural basis of audio-visual processing in speech and non-speech stimuli. Physically identical auditory stimuli (speech and sinusoidal tones) and visual stimuli (animated circles and ellipses) were used in this fMRI experiment. Relative to unimodal stimuli, each of the multimodal conjunctions showed increased activation in largely non-overlapping areas. The conjunction of Ellipse and Speech, which most resembles naturalistic audiovisual speech, showed higher activation in the right inferior frontal gyrus, fusiform gyri, left posterior superior temporal sulcus, and lateral occipital cortex. The conjunction of Circle and Tone, an arbitrary audio-visual pairing with no speech association, activated middle temporal gyri and lateral occipital cortex. The conjunction of Circle and Speech showed activation in lateral occipital cortex, and the conjunction of Ellipse and Tone did not show increased activation relative to unimodal stimuli. Further analysis revealed that middle temporal regions, although identified as multimodal only in the Circle-Tone condition, were more strongly active to Ellipse-Speech or Circle-Speech, but regions that were identified as multimodal for Ellipse-Speech were always strongest for Ellipse-Speech. Our results suggest that combinations of auditory and visual stimuli may together be processed by different cortical networks, depending on the extent to which speech or non-speech percepts are evoked. PMID:20709442

Top