Oxidative Stress, Inflammatory Biomarkers and Toxicity in Mouse Lung and Liver after Inhalation Exposure to 100% Biodiesel or Petroleum Diesel Emissions

EPA Science Inventory

BACKGROUND: Over the past decade, biodiesel (BD) has become a first alternative energy source that is economically viable and meets requirements of the Clean Air Act. Due to lower mass emissions and reduced hazardous compounds compared to diesel combustion emissions (CE), BD expo...

Recovery of forest residues in the Southern United States

Treesearch

Bryce J. Stokes; Donald L. Sirois

1989-01-01

In the mid 1970's, the accelerated price increases for petroleum products forced rapid exploration into and adoption of alternative energy sources. A viable option for the forest industry was the recovery of woody biomass from unmerchantable trees and logging residues. Several studies estimated that an abundance of such forest materials existed in the southeastern...

Energy Demand and Resources of Japan. Volume I

DTIC Science & Technology

1973-08-01

political motives. Economically Japan would prefer to develop alternative sources of petroleum which are politically stable and geologically viable...situation in the next decade. History records, therefore, Jhat Japan did not suddenly burst upon the scene as an advanced technology, highly competitive...cov- ering cooperative offshore exploration and eventual pro- duction in southern Kalimantan and northern Sumatra. Japex-Indonesian Limited, for

NASA Glenn Research Center Experience Using DOE Midwest Region Super ESPC

NASA Technical Reports Server (NTRS)

Zala, Laszlo F.

2000-01-01

The energy crisis of 1973 prompted the Federal Government and private industry to look into alternative methods to save energy. At the same time the constant reduction of operations and maintenance funds during the last 5 years forced Glenn Research Center (GRC) to look for alternative funding sources to meet the mandate to reduce energy consumption. The Super Energy Savings Performance Contract (ESPC) was chosen as a viable source of facility improvement funding that can create larger project scope and help replace aging, inefficient equipment. This paper describes Glenn's participation in the Department of Energy (DOE) Super ESPC program. This program provided Glenn cost savings in the performance of energy audits, preparation of documents, evaluation of proposals, and selection of energy service company (ESCO).

Renewable resources in the chemical industry--breaking away from oil?

PubMed

Nordhoff, Stefan; Höcker, Hans; Gebhardt, Henrike

2007-12-01

Rising prices for fossil-based raw materials suggest that sooner or later renewable raw materials will, in principle, become economically viable. This paper examines this widespread paradigm. Price linkages like those seen for decades particularly in connection with petrochemical raw materials are now increasingly affecting renewable raw materials. The main driving force is the competing utilisation as an energy source because both fossil-based and renewable raw materials are used primarily for heat, electrical power and mobility. As a result, prices are determined by energy utilisation. Simple observations show how prices for renewable carbon sources are becoming linked to the crude oil price. Whether the application calls for sugar, starch, virgin oils or lignocellulose, the price for the raw material rises with the oil price. Consequently, expectations regarding price trends for fossil-based energy sources can also be utilised for the valuation of alternative processes. However, this seriously calls into question the assumption that a rising crude oil price will favour the economic viability of alternative products and processes based on renewable raw materials. Conversely, it follows that these products and processes must demonstrate economic viability today. Especially in connection with new approaches in white biotechnology, it is evident that, under realistic assumptions, particularly in terms of achievable yields and the optimisation potential of the underlying processes, the route to utilisation is economically viable. This makes the paradigm mentioned at the outset at least very questionable.

Consideration of insects as a source of dietary protein for human consumption.

PubMed

Churchward-Venne, Tyler A; Pinckaers, Philippe J M; van Loon, Joop J A; van Loon, Luc J C

2017-12-01

Consumption of sufficient dietary protein is fundamental to muscle mass maintenance and overall health. Conventional animal-based protein sources such as meat (ie, beef, pork, lamb), poultry, fish, eggs, and dairy are generally considered high-quality sources of dietary protein because they meet all of the indispensable amino-acid requirements for humans and are highly digestible. However, the production of sufficient amounts of conventional animal-based protein to meet future global food demands represents a challenge. Edible insects have recently been proposed as an alternative source of dietary protein that may be produced on a more viable and sustainable commercial scale and, as such, may contribute to ensuring global food security. This review evaluates the protein content, amino-acid composition, and digestibility of edible insects and considers their proposed quality and potential as an alternative protein source for human consumption. © The Author(s) 2017. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Woody and herbaceous competition effects on the growth of naturally regenerated loblolly and shortleaf pines through 11 years

Treesearch

Michael D. Cain

1997-01-01

About 67% of pine stands in the southeastern United States originated from natural seedfall (USDA Forest Service 1988), and this method of regeneration continues to be important for perpetuating the species. If midstory and overstory hardwoods are controlled and there is an adequate pine seed source, natural pine regeneration is a viable alternative to artificial...

Clean technology: industry and environment, a viable partnership?

PubMed

Bull, A T

2000-04-01

The industrial sector is becoming increasingly interested in eliminating potential pollution at source and reducing energy use. Biotechnology provides cheaper, cleaner alternatives to a wide range of traditional processes--but its adoption has been slower than expected. If industry is to become truly compatible with the environment, companies and the public will have to be convinced of the ecological and economic value of clean technology.

Bioethics and deliberative democracy: five warnings from Hobbes.

PubMed

Trotter, Griffin

2006-06-01

Thomas Hobbes is one of the most ardent and thoroughgoing opponents of participatory democracy among Western political philosophers. Though Hobbes's alternative to participatory democracy-assent by subjects to rule by an absolute sovereign-no longer constitutes a viable political alternative for Westerners, his critique of participatory democracy is a potentially valuable source of insight about its liabilities. This essay elaborates five theses from Hobbes that stand as cogent warnings to those who embrace participatory democracy, especially those (such as most bioethicists) advocating for deliberative democracy based on a rational consensus model. In light of these warnings, the author suggests an alternative, modus vivendi approach to deliberative democracy that would radically alter the current practice of bioethics.

Manufacturing with the Sun

NASA Astrophysics Data System (ADS)

Murphy, L. M.; Hauser, S. G.; Clyne, R. J.

1992-05-01

Concentrated solar radiation is now a viable alternative energy source for many advanced manufacturing processes. Researchers at the National Renewable Energy Laboratory (NREL) have demonstrated the feasibility of processes such as solar-induced surface transformation of materials (SISTM), solar-based manufacturing, and solar-pumped lasers. Researchers are also using sunlight to decontaminate water and soils polluted with organic compounds; these techniques could provide manufacturers with innovative alternatives to traditional methods of waste management. The solar technology that is now being integrated into today's manufacturing processes offers even greater potential for tomorrow, especially as applied to the radiation-abundant environment available in space and on the lunar surface.

Manufacturing with the Sun

NASA Astrophysics Data System (ADS)

Murphy, Lawrence M.; Hauser, Steven G.; Clyne, Richard J.

1991-12-01

Concentrated solar radiation is now a viable alternative source for many advanced manufacturing processes. Researchers at the National Renewable Energy Laboratory (NREL) have demonstrated the feasibility of processes such as solar induced surface transformation of materials (SISTM), solar based manufacturing, and solar pumped lasers. Researchers are also using sunlight to decontaminate water and soils polluted with organic compounds; these techniques could provide manufacturers with innovative alternatives to traditional methods of waste management. The solar technology that is now being integrated into today's manufacturing processes offer greater potential for tomorrow, especially as applied to the radiation abundant environment available in space and on the lunar surface.

Manufacturing with the Sun

NASA Technical Reports Server (NTRS)

Murphy, Lawrence M.; Hauser, Steven G.; Clyne, Richard J.

1991-01-01

Concentrated solar radiation is now a viable alternative source for many advanced manufacturing processes. Researchers at the National Renewable Energy Laboratory (NREL) have demonstrated the feasibility of processes such as solar induced surface transformation of materials (SISTM), solar based manufacturing, and solar pumped lasers. Researchers are also using sunlight to decontaminate water and soils polluted with organic compounds; these techniques could provide manufacturers with innovative alternatives to traditional methods of waste management. The solar technology that is now being integrated into today's manufacturing processes offer greater potential for tomorrow, especially as applied to the radiation abundant environment available in space and on the lunar surface.

Comparing an optical parametric oscillator (OPO) as a viable alternative for mid-infrared tissue ablation with a free electron laser (FEL).

PubMed

Mackanos, Mark A; Simanovskii, Dmitrii M; Contag, Christopher H; Kozub, John A; Jansen, E Duco

2012-11-01

Beneficial medical laser ablation removes material efficiently with minimal collateral damage. A Mark-III free electron laser (FEL), at a wavelength of 6.45 μm has demonstrated minimal damage and high ablation yield in ocular and neural tissues. While this wavelength has shown promise for surgical applications, further advances are limited by the high overhead for FEL use. Alternative mid-infrared sources are needed for further development. We compared the FEL with a 5-μs pulse duration with a Q-switched ZGP-OPO with a 100-ns pulse duration at mid-infrared wavelengths. There were no differences in the ablation threshold of water and mouse dermis with these two sources in spite of the difference in their pulse structures. There was a significant difference in crater depth between the ZGP:OPO and the FEL. At 6.1 μm, the OPO craters are eight times the depth of the FEL craters. The OPO craters at 6.45 and 6.73 μm were six and five times the depth of the FEL craters, respectively. Bright-field (pump-probe) images showed the classic ablation mechanism from formation of a plume through collapse and recoil. The crater formation, ejection, and collapse phases occurred on a faster time-scale with the OPO than with the FEL. This research showed that a ZGP-OPO laser could be a viable alternative to FEL for clinical applications.

Jet Fuel from Shale Oil - 1981 Technology Review,

DTIC Science & Technology

1981-12-01

the programs just described by Mr Jackson in the previous papaer . F. N. Hodgson of the Mon- santo Research Center provided mass spectrometric... research and development efforts at alleviating the magnitude of the problem and its impact on national security by evaluating the potential of...with Exxon Research and Engineering, domestic oil shale was determined to be the most viable near term alternative source of syncrude available for

Marketing the gastrointestinal practice: strategic considerations.

PubMed

Berkowitz, Eric N

2006-10-01

The health care marketplace is changing rapidly with increasing competition, changing reimbursement, and greater shifting of cost to patients making them more price sensitive. To be financially viable, the successful gastrointestinal practice must be more market responsive in its approach to planning, develop a unique advantage that will be of value to referral sources, and understand how customers evaluate alternative competing practices. This article focuses on these elements of practice success.

The use of single room occupancy (SRO) housing as a residential alternative for persons with a chronic mental illness.

PubMed

Linhorst, D M

1991-04-01

The appropriateness of the use of single room occupancy (SRO) housing for persons with a mental illness is examined, along with the financing and management of SROs, and the provision of mental health services to SRO residents. SROs allow residents personal freedom and privacy, and they offer a sense of community that is capable of meeting a variety of needs. Proper management of SROs is essential to their success. Overall, SROs are found to be a viable source of housing and should be considered as one of several alternatives available to persons with a chronic mental illness.

NASA's GreenLab Research Facility: A Guide for a Self-Sustainable Renewable Energy Ecosystem

NASA Technical Reports Server (NTRS)

Bomani, B. M. McDowell; Hendricks, R. C.; Elbuluk, Malik; Okon, Monica; Lee, Eric; Gigante, Bethany

2011-01-01

There is a large gap between the production and demand for energy from alternative fuel and alternative renewable energy sources. The sustainability of humanity, as we know it, directly depends on the ability to secure affordable fuel, food, and freshwater. NASA Glenn Research Center (Glenn) has initiated a laboratory pilot study on using biofuels as viable alternative fuel resources for the field of aviation, as well as utilizing wind and solar technology as alternative renewable energy resources. The GreenLab Research Facility focuses on optimizing biomass feedstock using algae and halophytes as the next generation of renewable aviation fuels. The unique approach in this facility helps achieve optimal biomass feedstock through climatic adaptation of balanced ecosystems that do not use freshwater, compete with food crops, or use arable land. In addition, the GreenLab Research Facility is powered, in part, by alternative and renewable energy sources, reducing the major environmental impact of present electricity sources. The ultimate goal is to have a 100 percent clean energy laboratory that, when combined with biomass feedstock research, has the framework in place for a self-sustainable renewable energy ecosystem that can be duplicated anywhere in the world and can potentially be used to mitigate the shortage of food, fuel, and water. This paper describes the GreenLab Research Facility at Glenn and its power and energy sources, and provides recommendations for worldwide expansion and adoption of the facility s concept.

Lease/Purchase: A Viable Alternative for Financing Schools.

ERIC Educational Resources Information Center

Demers, Denise

1989-01-01

Lease-purchase finance is a viable alternative for school districts that cannot or do not want to employ traditional financing techniques. Outlines the advantages and disadvantages of lease-purchase financing compared to outright purchase; operating leasing, which is taxable; and traditional tax-exempt bond financing. (MLF)

Opportunities and challenges for seaweed in the biobased economy.

PubMed

van Hal, Jaap W; Huijgen, W J J; López-Contreras, A M

2014-05-01

The unique chemical composition of seaweeds and their fast growth rates offer many opportunities for biorefining. In this article we argue that cascading biorefinery valorization concepts are viable alternatives to only using seaweeds as carbohydrate sources for the fermentative production of biofuels. However, many challenges remain with respect to use of seaweeds for chemical production, such as the large seasonal variation in the chemical composition of seaweeds. Copyright © 2014 Elsevier Ltd. All rights reserved.

Applications of magnetic resonance spectroscopy to chitin from insect cuticles.

PubMed

Gonil, Pattarapond; Sajomsang, Warayuth

2012-11-01

Chitin is the second most abundant polysaccharide in nature after cellulose. At the present time, the main commercial sources of chitin are the crab and shrimp shells which are major waste products from the seafood industry. However, current chitin resources have some inherent problems including seasonal availability, limited supplies, and environmental pollution. As an alternative, insect cuticle is proposed as an unconventional but viable source of chitin. This review focuses on the recent sources of insect chitin and the application of various magnetic resonance spectroscopic techniques to native insect cuticles, particularly cicada sloughs and chitin extracted from insect sloughs. In addition, the physicochemical properties, isolation process, and degree of N-acetylation (DA) is reviewed and discussed. Copyright © 2012 Elsevier B.V. All rights reserved.

Renewable Hydrogen-Economically Viable: Integration into the U.S. Transportation Sector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kurtz, Jennifer; Peters, Mike; Muratori, Matteo

The U.S. transportation sector is expected to meet numerous goals in differing applications. These goals address security, safety, fuel source, emissions reductions, advanced mobility models, and improvements in quality and accessibility. Solutions to meeting these goals include a variety of alternative-fuel technologies, including batteries, fuel cells, synthetic fuels, and biofuels, as well as modifying how current transportation systems are used and integrating new systems, such as storing renewable energy. Overall, there are many combinations of problems, objectives, and solutions.

Color profiles and stability of acylated and nonacylated anthocyanins as novel pigment sources in a lipstick model: A viable alternative to synthetic colorants.

PubMed

Westfall, Alexandra; Giusti, Mónica

Cosmetics, such as lipstick, can affect an individual's perception of attractiveness and morale. Consumer concern with the safety of synthetic colorants has made the need for alternative natural color sources increasingly urgent. Our goal was to evaluate the feasibility of anthocyanin (ACN) extracts as colorants in lipstick formulations. Lipstick formulations were colored with ACN-rich materials. Accelerated environmental testing typical of the cosmetic industry were used: incubation at 20°, 37°, and 45°C for 12 weeks and temperature abuse cycles between 20°/37°C or -20°/20°C. Color (CIELab) and total monomeric ACN (pH-differential) changes were monitored to determine shelf stability of the product. All formulations exhibited acceptable color for lipsticks. Shelf stability was determined to exceed 2 year based on the accelerated testing conditions. Formulations containing cyanidin as their main ACN were the most stable (elderberry, purple corn, and purple sweet potato). ACNs could be used as suitable alternatives to synthetic colorants in lipid-based topical formulations.

Adaptive error detection for HDR/PDR brachytherapy: Guidance for decision making during real-time in vivo point dosimetry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kertzscher, Gustavo, E-mail: guke@dtu.dk; Andersen, Claus E., E-mail: clan@dtu.dk; Tanderup, Kari, E-mail: karitand@rm.dk

Purpose: This study presents an adaptive error detection algorithm (AEDA) for real-timein vivo point dosimetry during high dose rate (HDR) or pulsed dose rate (PDR) brachytherapy (BT) where the error identification, in contrast to existing approaches, does not depend on an a priori reconstruction of the dosimeter position. Instead, the treatment is judged based on dose rate comparisons between measurements and calculations of the most viable dosimeter position provided by the AEDA in a data driven approach. As a result, the AEDA compensates for false error cases related to systematic effects of the dosimeter position reconstruction. Given its nearly exclusivemore » dependence on stable dosimeter positioning, the AEDA allows for a substantially simplified and time efficient real-time in vivo BT dosimetry implementation. Methods: In the event of a measured potential treatment error, the AEDA proposes the most viable dosimeter position out of alternatives to the original reconstruction by means of a data driven matching procedure between dose rate distributions. If measured dose rates do not differ significantly from the most viable alternative, the initial error indication may be attributed to a mispositioned or misreconstructed dosimeter (false error). However, if the error declaration persists, no viable dosimeter position can be found to explain the error, hence the discrepancy is more likely to originate from a misplaced or misreconstructed source applicator or from erroneously connected source guide tubes (true error). Results: The AEDA applied on twoin vivo dosimetry implementations for pulsed dose rate BT demonstrated that the AEDA correctly described effects responsible for initial error indications. The AEDA was able to correctly identify the major part of all permutations of simulated guide tube swap errors and simulated shifts of individual needles from the original reconstruction. Unidentified errors corresponded to scenarios where the dosimeter position was sufficiently symmetric with respect to error and no-error source position constellations. The AEDA was able to correctly identify all false errors represented by mispositioned dosimeters contrary to an error detection algorithm relying on the original reconstruction. Conclusions: The study demonstrates that the AEDA error identification during HDR/PDR BT relies on a stable dosimeter position rather than on an accurate dosimeter reconstruction, and the AEDA’s capacity to distinguish between true and false error scenarios. The study further shows that the AEDA can offer guidance in decision making in the event of potential errors detected with real-timein vivo point dosimetry.« less

Within-Subject Interlaboratory Variability of QuantiFERON-TB Gold In-Tube Tests

DTIC Science & Technology

2012-09-06

QuantiFERONH-TB Gold In-Tube test (QFT-GIT) is a viable alternative to the tuberculin skin test (TST) for detecting Mycobacterium tuberculosis infection...viable alternative to the tuberculin skin test (TST) for detecting Mycobacterium tuberculosis infection. However, within-subject variability may limit test...release assays (IGRAs) are designed to detect both latent Mycobacterium tuberculosis infection (LTBI) and infections manifesting as active

Screening of chemical compound libraries identified new anti-Toxoplasma gondii agents.

PubMed

Adeyemi, Oluyomi Stephen; Sugi, Tatsuki; Han, Yongmei; Kato, Kentaro

2018-02-01

Toxoplasma gondii is the etiological agent of toxoplasmosis, a common parasitic disease that affects nearly one-third of the human population. The primary infection can be asymptomatic in healthy individuals but may prove fatal in immunocompromised individuals. Available treatment options for toxoplasmosis patients are limited, underscoring the urgent need to identify and develop new therapies. Non-biased screening of libraries of chemical compounds including the repurposing of well-characterized compounds is emerging as viable approach to achieving this goal. In the present investigation, we screened libraries of natural product and FDA-approved compounds to identify those that inhibited T. gondii growth. We identified 32 new compounds that potently inhibit T. gondii growth. Our findings are new and promising, and further strengthen the prospects of drug repurposing as well as the screening of a wide range of chemical compounds as a viable source of alternative anti-parasitic therapeutic agents.

Progress Toward Cleanup of Operable Unit 1 Groundwater at the US DOE Mound, Ohio, Site: Success of a Phase-Combined Remedy – 15310

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hooten, Gwendolyn; Cato, Rebecca; Looney, Brian

2015-03-01

Operable Unit 1 (OU-1) soil and groundwater have been affected by volatile organic compounds (VOC) Present groundwater remedy is collection, treatment, and disposal (pump and treat [P&T]) Several combinations of technologies were used to address soil and groundwater contamination Monitored natural attenuation (MNA) is a viable alternative Majority of source term has been excavated VOC concentrations in groundwater have decreased Attenuation mechanisms have been observed in the subsurface at OU-1

Sweetening Android Lemon Markets: Measuring and Curbing Malware in Application Marketplaces

DTIC Science & Technology

2012-06-08

the main software distribution mechanism for modern mobile devices but are also emerging as a viable alternative to brick -and- mortar stores for...mechanism for modern mobile devices but are also emerging as a viable alternative to brick -and- mortar stores for personal computers. While most...through the Apple App Store , thereby entirely forgoing the traditional distribution channel – packaged opti- cal media sold in brick -and- mortar

Farmers' Willingness to Adopt Conservation Agriculture: New Evidence from Lebanon.

PubMed

Chalak, Ali; Irani, Alexandra; Chaaban, Jad; Bashour, Issam; Seyfert, Karin; Smoot, Kaitlyn; Abebe, Gumataw Kifle

2017-10-01

With increasing food insecurity and climate change, conservation agriculture has emerged as a sustainable alternative to intensive conventional agriculture as a source of food supply. Yet the adoption rate of conservation agriculture is still low. Our paper analyses the factors affecting farmers' willingness to adopt conservation agriculture in Lebanon. The findings show that household characteristics-years of farming and farm size affect conservation agriculture adoption. However, household characteristics alone were insufficient to explain conservation agriculture adoption. We found that farming experience, information sources, frequency of irrigation, and severity of weed infestation in the past, participation in specific trainings, and farmers' perception about the long-term impact of conservation agriculture, were key determinants of conservation agriculture adoption. Our paper encourages policymakers to invest in conservation agriculture to overcome food insecurity and environmental changes affecting food systems in the Middle East. The paper also informs agribusiness firms to view conservation agriculture as a viable alternative to strengthen their business relationship with farmers in arid and semi-arid regions.

Farmers' Willingness to Adopt Conservation Agriculture: New Evidence from Lebanon

NASA Astrophysics Data System (ADS)

Chalak, Ali; Irani, Alexandra; Chaaban, Jad; Bashour, Issam; Seyfert, Karin; Smoot, Kaitlyn; Abebe, Gumataw Kifle

2017-10-01

With increasing food insecurity and climate change, conservation agriculture has emerged as a sustainable alternative to intensive conventional agriculture as a source of food supply. Yet the adoption rate of conservation agriculture is still low. Our paper analyses the factors affecting farmers' willingness to adopt conservation agriculture in Lebanon. The findings show that household characteristics—years of farming and farm size affect conservation agriculture adoption. However, household characteristics alone were insufficient to explain conservation agriculture adoption. We found that farming experience, information sources, frequency of irrigation, and severity of weed infestation in the past, participation in specific trainings, and farmers' perception about the long-term impact of conservation agriculture, were key determinants of conservation agriculture adoption. Our paper encourages policymakers to invest in conservation agriculture to overcome food insecurity and environmental changes affecting food systems in the Middle East. The paper also informs agribusiness firms to view conservation agriculture as a viable alternative to strengthen their business relationship with farmers in arid and semi-arid regions.

Economics of alternative energy sources.

PubMed

Ryle, M

1977-05-12

An important part of the oil and natural gas at present consumed in the UK is used for the heating of buildings, a demand which shows large diurnal, day-to-day and annual fluctuations. The replacement of this energy by nuclear-generated electricity, as at present envisaged, would require the construction of some 250 GW of additional capacity by the end of the century, a progamme which does not seem feasible. By incorporating relatively cheap, short term storage in the form of low-grade heat, the generating capacity required to fulfil peak demand could be reduced by more than 50%. As soon as such storage is provided, however, other sources of energy become viable and attractive alternatives, and the UK is well situated to make use of wind, wave, and tidal power. It seems likely that the value of North Sea oil/gas reserves as feedstock to the chemical industry will rise sufficiently to make an early reduction in their consumption as fuel of great economic importance.

Urea and urine are a viable and cost-effective nitrogen source for Yarrowia lipolytica biomass and lipid accumulation.

PubMed

Brabender, Matthew; Hussain, Murtaza Shabbir; Rodriguez, Gabriel; Blenner, Mark A

2018-03-01

Yarrowia lipolytica is an industrial yeast that has been used in the sustainable production of fatty acid-derived and lipid compounds due to its high growth capacity, genetic tractability, and oleaginous properties. This investigation examines the possibility of utilizing urea or urine as an alternative to ammonium sulfate as a nitrogen source to culture Y. lipolytica. The use of a stoichiometrically equivalent concentration of urea in lieu of ammonium sulfate significantly increased cell growth when glucose was used as the carbon source. Furthermore, Y. lipolytica growth was equally improved when grown with synthetic urine and real human urine. Equivalent or better lipid production was achieved when cells are grown on urea or urine. The successful use of urea and urine as nitrogen sources for Y. lipolytica growth highlights the potential of using cheaper media components as well as exploiting and recycling non-treated human waste streams for biotechnology processes.

Natural environmental water sources in endemic regions of northeastern Brazil are potential reservoirs of viable Mycobacterium leprae.

PubMed

Arraes, Maria Luisa Bezerra de Macedo; Holanda, Maísa Viana de; Lima, Luana Nepomuceno Gondim Costa; Sabadia, José Antônio Beltrão; Duarte, Cynthia Romariz; Almeida, Rosa Livia Freitas; Kendall, Carl; Kerr, Ligia Regina Sansigolo; Frota, Cristiane Cunha

2017-12-01

The detection of live Mycobacterium leprae in soil and animals other than humans suggests that the environment plays a role in the transmission of leprosy. The objective of this study was to investigate the presence of viable M. leprae in natural water sources used by the local population in five municipalities in the state of Ceará, northeastern Brazil. Samples were collected from 30 different sources. Viable bacilli were identified by reverse transcriptase polymerase chain reaction (PCR) of the M. leprae gyrA gene and sequencing of the PCR products. Physicochemical properties of each water source were also assessed. M. leprae gyrA mRNA was found in 23 (76.7%) of the water sources. No association was found between depth of the water and sample positivity, nor was there any association between the type of water used by the population and sample positivity. An association between viable M. leprae and temperature and pH was found. Georeferencing showed a relation between the residences of leprosy cases and water source containing the bacterium. The finding of viable M. leprae in natural water sources associated with human contact suggests that the environment plays an important role in maintaining endemic leprosy in the study region.

The Origin and Evolution of Interstellar Dust in the Local and High-redshift Universe

NASA Technical Reports Server (NTRS)

Dwek, Eliahu

2012-01-01

In this talk I will begin by reviewing our current state of knowledge regarding the origin and evolution of dust in the local solar neighborhood. using chemical evolution models, I will discuss their many different input parameters and their uncertainties. An important consequence of these models is the delayed injection of dust from AGB stars, compared to supernova-condensed dust, into the interstellar medium. I will show that these stellar evolutionary effects on dust composition are manifested in the infrared spectra of local galaxies. The delayed production of dust in AGB stars has also important consequences for the origin of the large amount of dust detected in high-redshift galaxies, when the universe was less that approx. 1 Gyr old. Supernovae may have been the only viable dust sources in those galaxies. Recent observations of sN1987a show a significant mass of dust in the ejecta of this SN. Is that production rate high enough to account for the observed dust mass in these galaxies? If not, what are the alternative viable sources of dust, and how do they depend on the nature of the galaxy (starburst or AGN) and its star formation history .

The Origin and Evolution of Interstellar Dust in the Local and High-Redshift Universe

NASA Technical Reports Server (NTRS)

Dwek, Eliahu

2011-01-01

In this talk I will begin by reviewing our current state of knowledge regarding the origin and evolution of dust in the local solar neighborhood. Using chemical evolution models, I will discuss their many different input parameters and their uncertainties. An important consequence of these models is the delayed injection of dust from AGB stars, compared to supernova-condensed dust, into the interstellar medium. I will show that these stellar evolutionary effects on dust composition are manifested in the infrared spectra of local galaxies. The delayed production of dust in AGB stars has also important consequences for the origin of the large amount of dust detected in high-redshift galaxies, when the universe was less that - 1 Gyr old. Supernovae may have been the only viable dust sources in those galaxies. Recent observations of SN1987a show a significant mass of dust in the ejecta of this SN. Is that production rate high enough to account for the observed dust mass in these galaxies? If not, what are the alternative viable sources of dust, and how do they depend on the nature of the galaxy (starburst or AGN) and its star formation history.

Solid-Phase Microextraction Coupled to Capillary Atmospheric Pressure Photoionization-Mass Spectrometry for Direct Analysis of Polar and Nonpolar Compounds.

PubMed

Mirabelli, Mario F; Zenobi, Renato

2018-04-17

A novel capillary ionization source based on atmospheric pressure photoionization (cAPPI) was developed and used for the direct interfacing between solid-phase microextraction (SPME) and mass spectrometry (MS). The efficiency of the source was evaluated for direct and dopant-assisted photoionization, analyzing both polar (e.g., triazines and organophosphorus pesticides) and nonpolar (polycyclic aromatic hydrocarbons, PAHs) compounds. The results show that the range of compound polarity, which can be addressed by direct SPME-MS can be substantially extended by using cAPPI, compared to other sensitive techniques like direct analysis in real time (DART) and dielectric barrier discharge ionization (DBDI). The new source delivers a very high sensitivity, down to sub parts-per-trillion (ppt), making it a viable alternative when compared to previously reported and less comprehensive direct approaches.

Near-field interferometry of a free-falling nanoparticle from a point-like source

NASA Astrophysics Data System (ADS)

Bateman, James; Nimmrichter, Stefan; Hornberger, Klaus; Ulbricht, Hendrik

2014-09-01

Matter-wave interferometry performed with massive objects elucidates their wave nature and thus tests the quantum superposition principle at large scales. Whereas standard quantum theory places no limit on particle size, alternative, yet untested theories—conceived to explain the apparent quantum to classical transition—forbid macroscopic superpositions. Here we propose an interferometer with a levitated, optically cooled and then free-falling silicon nanoparticle in the mass range of one million atomic mass units, delocalized over >150 nm. The scheme employs the near-field Talbot effect with a single standing-wave laser pulse as a phase grating. Our analysis, which accounts for all relevant sources of decoherence, indicates that this is a viable route towards macroscopic high-mass superpositions using available technology.

Cultivation Of Microalgae (Chlorella vulgaris) For Biodiesel Production

NASA Astrophysics Data System (ADS)

Blinová, Lenka; Bartošová, Alica; Gerulová, Kristína

2015-06-01

Production of biofuel from renewable sources is considered to be one of the most sustainable alternatives to petroleum sourced fuels. Biofuels are also viable means of environmental and economic sustainability. Biofuels are divided into four generations, depending on the type of biomass used for biofuels production. At present, microalgae are presented as an ideal third generation biofuel feedstock because of their rapid growth rate. They also do not compete with food or feed crops, and can be produced on non-arable land. Cultivation conditions (temperature, pH, light, nutrient quantity and quality, salinity, aerating) are the major factors that influence photosynthesis activity and behaviour of the microalgae growth rate. In this paper, we present an overview about the effect of cultivation conditions on microalgae growth.

Introductory assessment of orbiting reflections for terrestrial power generation

NASA Technical Reports Server (NTRS)

Billman, K. W.; Gilbreath, W. P.; Bowen, S. W.

1977-01-01

The use of orbiting mirrors for providing energy to ground conversion stations to produce electrical power is shown to be a viable, cost effective and environmentally sound alternative to satellite solar power stations and conventional power sources. This is accomplished with the use of very light weight metal coated polymeric films as mirrors which, after deployment at 800 km, are placed in operational orbit and controlled by solar radiation pressure. Relations are developed showing the influence of a number of parameters (mirror altitude, orbit inclination, period, mirror size and number, and atmospheric effects) on the reflected insolation that may be received by a ground spot as a function of location. Some attractive alternative uses of the reflection are briefly discussed as a beneficial adjuncts to the system.

Occurrence and availability of ground water in the Athens region, northeastern Georgia

USGS Publications Warehouse

Radtke, D.B.; Cressler, C.W.; Perlman, H.A.; Blanchard, H.E.; McFadden, K.W.; Brooks, Rebekah

1986-01-01

A study was conducted to assess the occurrence and availability of groundwater in the crystalline rocks of the Piedmont area in northeastern Georgia and to determine whether groundwater is a viable alternative or supplemental source for industrial, public and private supplies. The area is underlain by a variety of metamorphic and igneous rocks. The quantity of water that a rock unit can supply to wells is determined by the number, capacity, and interconnection of the secondary openings. Of an estimated 10,000 successful wells drilled in the Athens Region, 972 wells are reported by drilling contractors to supply from 20 to 300 gal/min. Studies of well sites revealed that high yielding wells can be developed only where the water bearing units have undergone significant increases in secondary permeability. This occurs mainly in association with (1) contact zones between rock units of contrasting character, (2) contact zones within multilayered rock units, (3) fault zones, (4) stress-relief fractures, and (5) shear zones. Groundwater may be a viable alternative or supplemental source for industrial, public, and private supplies in much of the Athens Region. In 1980, groundwater made up 38% (18 million gal/day) of the total water used in the area. Yields of 20 to more than 200 gal/min are obtained from wells throughout most of the region, and the water is generally of good chemical quality and is suitable for drinking and many other uses. Concentrations of dissolved constituents are fairly consistent throughout the area. Except for iron, manganese, and fluoride, dissolved constituents rarely exceed drinking water standards. (Lantz-PTT)

Evaluation of alternative snowplowable markers and snowplowing procedures.

DOT National Transportation Integrated Search

2013-06-01

The objectives of this study were to investigate viable alternatives to the currently approved snowplowable raised pavement marker and alternative methods and equipment used to snowplow roadways. The study included evaluating any potential durable an...

Towards quantitative PET/MRI: a review of MR-based attenuation correction techniques.

PubMed

Hofmann, Matthias; Pichler, Bernd; Schölkopf, Bernhard; Beyer, Thomas

2009-03-01

Positron emission tomography (PET) is a fully quantitative technology for imaging metabolic pathways and dynamic processes in vivo. Attenuation correction of raw PET data is a prerequisite for quantification and is typically based on separate transmission measurements. In PET/CT attenuation correction, however, is performed routinely based on the available CT transmission data. Recently, combined PET/magnetic resonance (MR) has been proposed as a viable alternative to PET/CT. Current concepts of PET/MRI do not include CT-like transmission sources and, therefore, alternative methods of PET attenuation correction must be found. This article reviews existing approaches to MR-based attenuation correction (MR-AC). Most groups have proposed MR-AC algorithms for brain PET studies and more recently also for torso PET/MR imaging. Most MR-AC strategies require the use of complementary MR and transmission images, or morphology templates generated from transmission images. We review and discuss these algorithms and point out challenges for using MR-AC in clinical routine. MR-AC is work-in-progress with potentially promising results from a template-based approach applicable to both brain and torso imaging. While efforts are ongoing in making clinically viable MR-AC fully automatic, further studies are required to realize the potential benefits of MR-based motion compensation and partial volume correction of the PET data.

Distributed renewable power from biomass and other waste fuels

NASA Astrophysics Data System (ADS)

Lyons, Chris

2012-03-01

The world population is continually growing and putting a burden on our fossil fuels. These fossil fuels such as coal, oil and natural gas are used for a variety of critical needs such as power production and transportation. While significant environmental improvements have been made, the uses of these fuels are still causing significant ecological impacts. Coal power production efficiency has not improved over the past thirty years and with relatively cheap petroleum cost, transportation mileage has not improved significantly either. With the demand for these fossil fuels increasing, ultimately price will also have to increase. This presentation will evaluate alternative power production methods using localized distributed generation from biomass, municipal solid waste and other waste sources of organic materials. The presentation will review various gasification processes that produce a synthetic gas that can be utilized as a fuel source in combustion turbines for clean and efficient combined heat and power. This fuel source can produce base load renewable power. In addition tail gases from the production of bio-diesel and methanol fuels can be used to produce renewable power. Being localized can reduce the need for long and costly transmission lines making the production of fuels and power from waste a viable alternative energy source for the future.

Determination of viable Salmonellae from potable and source water through PMA assisted qPCR.

PubMed

Singh, Gulshan; Vajpayee, Poornima; Bhatti, Saurabh; Ronnie, Nirmala; Shah, Nimish; McClure, Peter; Shanker, Rishi

2013-07-01

Resource constrained countries identified as endemic zones for pathogenicity of Salmonella bear an economic burden due to recurring expenditure on medical treatment. qPCR used for Salmonella detection could not discriminate between viable and nonviable cells. Propidium monoazide (PMA) that selectively penetrates nonviable cells to cross-link their DNA, was coupled with ttr gene specific qPCR for quantifying viable salmonellae in source/potable waters collected from a north Indian city. Source water (raw water for urban potable water supply) and urban potable water exhibited viable salmonellae in the range of 2.1×10(4)-2.6×10(6) and 2-7160CFU/100mL, respectively. Potable water at water works exhibited DNA from dead cells but no viable cells were detected. PMA assisted qPCR could specifically detect low numbers of live salmonellae in Source and potable waters. This strategy can be used in surveillance of urban potable water distribution networks to map contamination points for better microbial risk management. Copyright © 2013 Elsevier Inc. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

He, W.; Zhao, H.W.; Liu, Zh.W.

To study the injection of additional electrons from an external electron gun into the plasma of a Penning ionization gauge (PIG) ion source, a test bench for the external electron-beam enhancement of the PIG (E-PIG) ion source was set up. A source magnet assembly was built to satisfy the request for magnetic field configuration of the E-PIG ion source. Numerical calculations have been done to optimize the magnetic field configuration so as to fit the primary electrons to be fed into the PIG discharge chamber along the spreading magnetic field lines. Many possible methods for improving the performance and stabilitymore » of the PIG ion source have been used in the E-PIG ion source, including the use of multicrystal LaB{sub 6} cathode and optimized axial magnetic field. This article presents a detailed design of the E-PIG ion source. Substantial enhancement of ion charge state is expected to be observed which demonstrates that the E-PIG is a viable alternative to other much more costly and difficult to operate devices for the production of intense ion beams of higher charge state.« less

A Statistical Review of Alternative Zinc and Copper Extraction from Mineral Fertilizers and Industrial By-Products.

PubMed

Cenciani de Souza, Camila Prado; Aparecida de Abreu, Cleide; Coscione, Aline Renée; Alberto de Andrade, Cristiano; Teixeira, Luiz Antonio Junqueira; Consolini, Flavia

2018-01-01

Rapid, accurate, and low-cost alternative analytical methods for micronutrient quantification in fertilizers are fundamental in QC. The purpose of this study was to evaluate whether zinc (Zn) and copper (Cu) content in mineral fertilizers and industrial by-products determined by the alternative methods USEPA 3051a, 10% HCl, and 10% H2SO4 are statistically equivalent to the standard method, consisting of hot-plate digestion using concentrated HCl. The commercially marketed Zn and Cu sources in Brazil consisted of oxides, carbonate, and sulfate fertilizers and by-products consisting of galvanizing ash, galvanizing sludge, brass ash, and brass or scrap slag. The contents of sources ranged from 15 to 82% and 10 to 45%, respectively, for Zn and Cu. The Zn and Cu contents refer to the variation of the elements found in the different sources evaluated with the concentrated HCl method as shown in Table 1. A protocol based on the following criteria was used for the statistical analysis assessment of the methods: F-test modified by Graybill, t-test for the mean error, and linear correlation coefficient analysis. In terms of equivalents, 10% HCl extraction was equivalent to the standard method for Zn, and the results of the USEPA 3051a and 10% HCl methods indicated that these methods were equivalents for Cu. Therefore, these methods can be considered viable alternatives to the standard method of determination for Cu and Zn in mineral fertilizers and industrial by-products in future research for their complete validation.

Photovoltaic power - An important new energy option

NASA Technical Reports Server (NTRS)

Ferber, R. R.

1983-01-01

A review of photovoltaic (PV) power technology is presented with an emphasis of PV as an economical and technically feasible alternative source of energy. The successful completion of the development and transfer of emerging low-cost technologies into a fully commercialized status are identified as the means to the realization of this option's full potential. The DOE National Photovoltaics Program, a significant sponsor of PV R&D, expects both flat-plate and concentrator collectors to meet established cost targets. Citing the DOE large flat-plate grid-connected system project of the Sacramento Municipal Utility District, current technology modules priced at near $5/Wp (1983 dollars) are steadily reducing costs. A recent DOE study suggests that PV-generated electricity produced at a 30-year levelized cost of 15 cents per kWh would represent a viable energy supply alternative for the nation.

Photovoltaic power - An important new energy option

NASA Astrophysics Data System (ADS)

Ferber, R. R.

1983-12-01

A review of photovoltaic (PV) power technology is presented with an emphasis of PV as an economical and technically feasible alternative source of energy. The successful completion of the development and transfer of emerging low-cost technologies into a fully commercialized status are identified as the means to the realization of this option's full potential. The DOE National Photovoltaics Program, a significant sponsor of PV R&D, expects both flat-plate and concentrator collectors to meet established cost targets. Citing the DOE large flat-plate grid-connected system project of the Sacramento Municipal Utility District, current technology modules priced at near $5/Wp (1983 dollars) are steadily reducing costs. A recent DOE study suggests that PV-generated electricity produced at a 30-year levelized cost of 15 cents per kWh would represent a viable energy supply alternative for the nation.

Biomass power in transition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marshall, D.K.

1996-12-31

Electricity production from biomass fuel has been hailed in recent years as an environmentally acceptable energy source that delivers on its promise of economically viable renewable energy. A Wall Street Journal article from three years ago proclaimed wood to be {open_quotes}moving ahead of costly solar panels and wind turbines as the leading renewable energy alternative to air-fouling fossils fuels and scary nuclear plants.{close_quotes} Biomass fuel largely means wood; about 90% of biomass generated electricity comes from burning waste wood, the remainder from agricultural wastes. Biomass power now faces an uncertain future. The maturing of the cogeneration and independent power plantmore » market, restructuring of the electric industry, and technological advances with power equipment firing other fuels have placed biomass power in a competitive disadvantage with other power sources.« less

Microbial fuel cells as an alternative energy source: current status.

PubMed

Javed, Muhammad Mohsin; Nisar, Muhammad Azhar; Ahmad, Muhammad Usman; Yasmeen, Nighat; Zahoor, Sana

2018-06-22

Microbial fuel cell (MFC) technology is an emerging area for alternative renewable energy generation and it offers additional opportunities for environmental bioremediation. Recent scientific studies have focused on MFC reactor design as well as reactor operations to increase energy output. The advancement in alternative MFC models and their performance in recent years reflect the interests of scientific community to exploit this technology for wider practical applications and environmental benefit. This is reflected in the diversity of the substrates available for use in MFCs at an economically viable level. This review provides an overview of the commonly used MFC designs and materials along with the basic operating parameters that have been developed in recent years. Still, many limitations and challenges exist for MFC development that needs to be further addressed to make them economically feasible for general use. These include continued improvements in fuel cell design and efficiency as well scale-up with economically practical applications tailored to local needs.

Chemical Processing of Non-Crop Plants for Jet Fuel Blends Production

NASA Technical Reports Server (NTRS)

Kulis, M. J.; Hepp, A. F.; McDowell, M.; Ribita, D.

2009-01-01

The use of Biofuels has been gaining in popularity over the past few years due to their ability to reduce the dependence on fossil fuels. Biofuels as a renewable energy source can be a viable option for sustaining long-term energy needs if they are managed efficiently. We describe our initial efforts to exploit algae, halophytes and other non-crop plants to produce synthetics for fuel blends that can potentially be used as fuels for aviation and non-aerospace applications. Our efforts have been dedicated to crafting efficient extraction and refining processes in order to extract constituents from the plant materials with the ultimate goal of determining the feasibility of producing biomass-based jet fuel from the refined extract. Two extraction methods have been developed based on communition processes, and liquid-solid extraction techniques. Refining procedures such as chlorophyll removal and transesterification of triglycerides have been performed. Gas chromatography in tandem with mass spectroscopy is currently being utilized in order to qualitatively determine the individual components of the refined extract. We also briefly discuss and compare alternative methods to extract fuel-blending agents from alternative biofuels sources.

Should Live Patient Licensing Examinations in Dentistry Be Discontinued? Two Viewpoints: Viewpoint 1: Alternative Assessment Models Are Not Yet Viable Replacements for Live Patients in Clinical Licensure Exams and Viewpoint 2: Ethical and Patient Care Concerns About Live Patient Exams Require Full Acceptance of Justifiable Alternatives.

PubMed

Chu, Tien-Min Gabriel; Makhoul, Nicholas M; Silva, Daniela Rodrigues; Gonzales, Theresa S; Letra, Ariadne; Mays, Keith A

2018-03-01

This Point/Counterpoint article addresses a long-standing but still-unresolved debate on the advantages and disadvantages of using live patients in dental licensure exams. Two contrasting viewpoints are presented. Viewpoint 1 supports the traditional use of live patients, arguing that other assessment models have not yet been demonstrated to be viable alternatives to the actual treatment of patients in the clinical licensure process. This viewpoint also contends that the use of live patients and inherent variances in live patient treatment represent the realities of daily private practice. Viewpoint 2 argues that the use of live patients in licensure exams needs to be discontinued considering those exams' ethical dilemmas of exposing patients to potential harm, as well as their lack of reliability and validity and limited scope. According to this viewpoint, the current presence of viable alternatives means that the risk of harm inherent in live patient exams can finally be eliminated and those exams replaced with other means to confirm that candidates are qualified for licensure to practice.

Alternative approaches to providing passenger transportation in low density cities : the case of Council Bluffs, Iowa

DOT National Transportation Integrated Search

1997-09-01

This study explores transportation alternatives for Council Bluffs. The intention is to explore alternatives that may potentially prove viable for other small cities faced with scattered development patterns and limited population density. The study ...

Characterization of Complementary and Alternative Medicine-Related Consultations in an Academic Drug Information Service.

PubMed

Gregory, Philip J; Jalloh, Mohamed A; Abe, Andrew M; Hu, James; Hein, Darren J

2016-12-01

To characterize requests received through an academic drug information consultation service related to complementary and alternative medicines. A retrospective review and descriptive analysis of drug information consultations was conducted. A total of 195 consultations related to complementary and alternative medicine were evaluated. All consultation requests involved questions about dietary supplements. The most common request types were related to safety and tolerability (39%), effectiveness (38%), and therapeutic use (34%). Sixty-eight percent of the requests were from pharmacists. The most frequent consultation requests from pharmacists were questions related to drug interactions (37%), therapeutic use (37%), or stability/compatibility/storage (34%). Nearly 60% of complementary and alternative medicine-related consultation requests were able to be completely addressed using available resources. Among review sources, Natural Medicines Comprehensive Database, Clinical Pharmacology, Micromedex, and Pharmacist's Letter were the most common resources used to address consultations. Utilization of a drug information service may be a viable option for health care professionals to help answer a complementary and alternative medicine-related question. Additionally, pharmacists and other health care professionals may consider acquiring resources identified to consistently answering these questions. © The Author(s) 2015.

Economically viable biochemical processes for the advanced rural biorefinery and downstream recovery operations

USDA-ARS?s Scientific Manuscript database

Rural biorefineries offer an alternative to traditional ethanol production by providing the opportunity to produce fuel on site to reduce costs associated with biomass transportation thus making the fuel economically viable. Widespread installation of rural biorefineries could lead to increased upt...

A high brightness source for nano-probe secondary ion mass spectrometry

NASA Astrophysics Data System (ADS)

Smith, N. S.; Tesch, P. P.; Martin, N. P.; Kinion, D. E.

2008-12-01

The two most prevalent ion source technologies in the field of surface analysis and surface machining are the Duoplasmatron and the liquid metal ion source (LMIS). There have been many efforts in this area of research to develop an alternative source [ S.K. Guharay, J. Orloff, M. Wada, IEEE Trans. Plasma Sci. 33 (6) (2005) 1911; N.S. Smith, W.P. Skoczylas, S.M. Kellogg, D.E. Kinion, P.P. Tesch, O. Sutherland, A. Aanesland, R.W. Boswell, J. Vac. Sci. Technol. B 24 (6) (2006) 2902-2906] with the brightness of a LMIS and yet the ability to produce secondary ion yield enhancing species such as oxygen. However, to date a viable alternative has not been realized. The high brightness and small virtual source size of the LMIS are advantageous for forming high resolution probes but a significant disadvantage when beam currents in excess of 100 nA are required, due to the effects of spherical aberration from the optical column. At these higher currents a source with a high angular intensity is optimal and in fact the relatively moderate brightness of today's plasma ion sources prevail in this operating regime. Both the LMIS and Duoplasmatron suffer from a large axial energy spread resulting in further limitations when forming focused beams at the chromatic limit where the figure-of-merit is inversely proportional to the square of the energy spread. Also, both of these ion sources operate with a very limited range of ion species. This article reviews some of the latest developments and some future potential in this area of instrument development. Here we present an approach to source development that could lead to oxygen ion beam SIMS imaging with 10 nm resolution, using a 'broad area' RF gas phase ion source.

Improving protein production of indigenous microalga Chlorella vulgaris FSP-E by photobioreactor design and cultivation strategies.

PubMed

Chen, Chun-Yen; Lee, Po-Jen; Tan, Chung Hong; Lo, Yung-Chung; Huang, Chieh-Chen; Show, Pau Loke; Lin, Chih-Hung; Chang, Jo-Shu

2015-06-01

Fish meal is currently the major protein source for commercial aquaculture feed. Due to its unstable supply and increasing price, fish meal is becoming more expensive and its availability is expected to face significant challenges in the near future. Therefore, feasible alternatives to fish meal are urgently required. Microalgae have been recognized as the most promising candidates to replace fish meal because the protein composition of microalgae is similar to fish meal and the supply of microalgae-based proteins is sustainable. In this study, an indigenous microalga (Chlorella vulgaris FSP-E) with high protein content was selected, and its feasibility as an aquaculture protein source was explored. An innovative photobioreactor (PBR) utilizing cold cathode fluorescent lamps as an internal light source was designed to cultivate the FSP-E strain for protein production. This PBR could achieve a maximum biomass and protein productivity of 699 and 365 mg/L/day, respectively, under an optimum urea and iron concentration of 12.4 mM and 90 μM, respectively. In addition, amino acid analysis of the microalgal protein showed that up to 70% of the proteins in this microalgal strain consist of indispensable amino acids. Thus, C. vulgaris FSP-E appears to be a viable alternative protein source for the aquaculture industry. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Dual potential of microalgae as a sustainable biofuel feedstock and animal feed

PubMed Central

2013-01-01

The rise in global population has led to explorations of alternative sources of energy and food. Because corn and soybean are staple food crops for humans, their common use as the main source of dietary energy and protein for food-producing animals directly competes with their allocation for human consumption. Alternatively, de-fatted marine microalgal biomass generated from the potential biofuel production may be a viable replacement of corn and soybean meal due to their high levels of protein, relatively well-balanced amino acid profiles, and rich contents of minerals and vitamins, along with unique bioactive compounds. Although the full-fatted (intact) microalgae represent the main source of omega-3 (n-3) polyunsaturated fatty acids including docohexaenoic acid (DHA) and eicosapentaenoic acid (EPA), the de-fatted microalgal biomass may still contain good amounts of these components for enriching DHA/EPA in eggs, meats, and milk. This review is written to highlight the necessity and potential of using the de-fatted microalgal biomass as a new generation of animal feed in helping address the global energy, food, and environmental issues. Nutritional feasibility and limitation of the biomass as the new feed ingredient for simple-stomached species are elaborated. Potential applications of the biomass for generating value-added animal products are also explored. PMID:24359607

Comprehensive Review of Adipose Stem Cells and Their Implication in Distraction Osteogenesis and Bone Regeneration

PubMed Central

Morcos, Mina W.; Al-Jallad, Hadil; Hamdy, Reggie

2015-01-01

Bone is one of the most dynamic tissues in the human body that can heal following injury without leaving a scar. However, in instances of extensive bone loss, this intrinsic capacity of bone to heal may not be sufficient and external intervention becomes necessary. Several techniques are available to address this problem, including autogenous bone grafts and allografts. However, all these techniques have their own limitations. An alternative method is the technique of distraction osteogenesis, where gradual and controlled distraction of two bony segments after osteotomy leads to induction of new bone formation. Although distraction osteogenesis usually gives satisfactory results, its major limitation is the prolonged duration of time required before the external fixator is removed, which may lead to numerous complications. Numerous methods to accelerate bone formation in the context of distraction osteogenesis have been reported. A viable alternative to autogenous bone grafts for a source of osteogenic cells is mesenchymal stem cells from bone marrow. However, there are certain problems with bone marrow aspirate. Hence, scientists have investigated other sources for mesenchymal stem cells, specifically adipose tissue, which has been shown to be an excellent source of mesenchymal stem cells. In this paper, the potential use of adipose stem cells to stimulate bone formation is discussed. PMID:26448947

Space power system design and development from an economic point of view

NASA Technical Reports Server (NTRS)

Hazelrigg, G. A., Jr.

1977-01-01

The concept of a satellite solar power system offers a feasible, but unproven, long-range energy alternative. While the basic physics of these systems is understood, many developments are necessary in order to reduce the system cost to the point of being cost-competitive with alternative energy sources. Thus, a substantial technology advancement and verification program, plus test and demonstration satellite programs are necessary before a full-scale satellite can be designed and built. It is important to properly identify those elements of the technology that should be subject to development efforts, the goals of the corresponding development programs and the appropriate funding levels and schedules. Systems studies and designs play a major role in rationally formulating a development program. This paper uses an economic approach to place these studies into a framework for formulating a viable satellite solar power system development plan.

Design concepts for bioreactors in space

NASA Technical Reports Server (NTRS)

Seshan, P. K.; Peterson, G. R.; Beard, B.; Dunlop, E. H.

1986-01-01

Microbial food sources are becoming viable and more efficient alternatives to conventional food sources especially in the context of Closed Ecological Life Support Systems (CELSS) in space habitats. Since bioreactor designs for terrestrial operation will not readily apply to conditions of microgravity, there is an urgent need to learn about the differences. These differences cannot be easily estimated due to the complex nature of the mass transport and mixing mechanisms in fermenters. Therefore, a systematic and expeditious experimental program must be undertaken to obtain the engineering data necessary to lay down the foundations of designing bioreactors for microgravity. Two bioreactor design concepts presented represent two dissimilar approaches to grappling with the absence of gravity in space habitats and deserve to be tested for adoption as important components of the life support function aboard spacecrafts, space stations and other extra-terrestrial habitats.

Using a Network of Flux Towers to Investigate the Effects of Wetland Restoration on Greenhouse Gas Fluxes

NASA Astrophysics Data System (ADS)

Baldocchi, D. D.; Hatala, J.; Knox, S.; Verfaillie, J. G.; Anderson, F.

2012-12-01

The Sacramento-San Joaquin Delta, a peatland and former wetland, was drained a 100 years ago for intensive agriculture. In the interim, over 10 m of peat has been lost, mostly through oxidation. Current land use is not sustainable, if this region is to maintain its integrity and serve as a conduit for freshwater pumped from northern to southern California. There is great interest in restoring this disturbed landscape with tule wetlands or rice; one is an effective carbon sink, the other an economically viable alternative. Questions arise to how effective are these new landscapes in sequestering carbon and what are the unintended consequences, such as the production of methane and high rates of evaporation from flooded lands, in a semi-arid climate? We are currently operating 6 eddy covariance flux systems that measure short and long term fluxes of carbon dioxide, water vapor and methane. We are making flux measurements over landscapes that represent business as usual (irrigated pasture and corn) and new alternatives (rice, a newly restored wetland and a 14 year old wetland). The pasture and corn operate as carbon sources and are weak emitters of methane on annual time scales. The rice is a modest sink of carbon dioxide, but becomes a carbon source when harvesting is considered. It is a smaller source of methane compared to rice growing in the Sacramento Valley on clay. It seems that there are sufficient alternative electron acceptors (iron, nitrate) that moderate methane production for rice growing on peat soils. The newly restored wetland is a huge methane source, with fluxes exceeding 300 nmol m-2 s-1. In the first two years of functioning, following disturbance, it is switching from being a carbon source to a sink, as tules fill the landscape. The older wetland remains a strong methane source, and its carbon dioxide sink potential is diminishing at it becomes derelict with much undecomposed vegetation.

Alternative Fuels Data Center: Coca-Cola Bottling Co. Brings Hybrids to New

Science.gov Websites

as a great example of a viable clean transportation option for similar fleets. " Rebecca Otte commitment to a more sustainable community and serves as a great example of a viable clean transportation , individual bottling companies now operate these vehicles. For example, Coca-Cola Bottling Company United

Innovative Treatment Technologies for Natural Waters and Wastewaters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Childress, Amy E.

2011-07-01

The research described in this report focused on the development of novel membrane contactor processes (in particular, forward osmosis (FO), pressure retarded osmosis (PRO), and membrane distillation (MD)) in low energy desalination and wastewater treatment applications and in renewable energy generation. FO and MD are recently gaining national and international attention as viable, economic alternatives for removal of both established and emerging contaminants from natural and process waters; PRO is gaining worldwide attention as a viable source of renewable energy. The interrelationship of energy and water are at the core of this study. Energy and water are inextricably bound; energymore » usage and production must be considered when evaluating any water treatment process for practical application. Both FO and MD offer the potential for substantial energy and resource savings over conventional treatment processes and PRO offers the potential for renewable energy or energy offsets in desalination. Combination of these novel technologies with each other, with existing technologies (e.g., reverse osmosis (RO)), and with existing renewable energy sources (e.g., salinity gradient solar ponds) may enable much less expensive water production and also potable water production in remote or distributed locations. Two inter-related projects were carried out in this investigation. One focused on membrane bioreactors for wastewater treatment and PRO for renewable energy generation; the other focused on MD driven by a salinity gradient solar pond.« less

Variation at work: alternations between physically and mentally demanding tasks in blue-collar occupations.

PubMed

Jahncke, Helena; Hygge, Staffan; Mathiassen, Svend Erik; Hallman, David; Mixter, Susanna; Lyskov, Eugene

2017-09-01

The aims of this questionnaire study were to describe the occurrence and desired number of alternations between mental and physical tasks in industrial and non-industrial blue-collar work, and determine to which extent selected personal and occupational factors influence these conditions. On average, the 122 participating workers (55 females) reported to have close to four alternations per day between mental and physical tasks, and to desire more alternations than they actually had. They also expressed a general preference for performing a physical task after a mental task and vice versa. In univariate regression models, the desired change in task alternations was significantly associated with gender, age, occupation, years with current work tasks and perceived job control, while occupation was the only significant determinant in a multiple regression model including all factors. Our results suggest that alternations between productive physical and mental tasks could be a viable option in future job rotation. Practitioner Summary: We addressed attitudes among blue-collar workers to alternations between physically and mentally demanding tasks. More alternations were desired than those occurring in the job, and workers preferred performing a physical task after a mental and vice versa. Alternating physical and mental tasks could, thus, be a viable option in job rotation.

Development of a 500-Watt portable generator

NASA Astrophysics Data System (ADS)

Knochenhauer, Robert John

In many commercial and recreational environments where power is unavailable, there is a need for lightweight, efficient, reasonably priced and quiet power sources that can recharge batteries for various portable devices. The current benchmark device is the Honda EU1000i, a 1000-Watt (peak) generator that weighs only 29 pounds (dry) and has a respectable noise level of 59 dB (at 7 meters) under peak power loading. The intent of this thesis study is to focus on the thermal management of a novel generator design that develops peak power of 500-Watts, weighs in at less than 20 pounds (dry) and has a reasonably low noise level at peak power loading. Through the course of this assessment, two key lessons are learned: • Liquid cooling at this scale is possible, but not practical • Renewable power sources (wind turbines and/or solar panels) are viable alternatives when used in environments that offer suitable conditions.

Quality Alternative Certification Programs in Special Education Ensure High Retention

ERIC Educational Resources Information Center

Karge, Belinda D.; McCabe, Marjorie

2014-01-01

Market driven alternative routes to teaching have evolved into a quality program option and not just an answer to the teacher shortage. Alternative certification is a viable means of recruiting, training, and certifying those who have a bachelor's degree and a strong desire to enter the field of teaching. California has been a leader in the…

Edible insects are the future?

PubMed

van Huis, Arnold

2016-08-01

The global increase in demand for meat and the limited land area available prompt the search for alternative protein sources. Also the sustainability of meat production has been questioned. Edible insects as an alternative protein source for human food and animal feed are interesting in terms of low greenhouse gas emissions, high feed conversion efficiency, low land use, and their ability to transform low value organic side streams into high value protein products. More than 2000 insect species are eaten mainly in tropical regions. The role of edible insects in the livelihoods and nutrition of people in tropical countries is discussed, but this food source is threatened. In the Western world, there is an increasing interest in edible insects, and examples are given. Insects as feed, in particular as aquafeed, have a large potential. Edible insects have about the same protein content as conventional meat and more PUFA. They may also have some beneficial health effects. Edible insects need to be processed and turned into palatable dishes. Food safety may be affected by toxicity of insects, contamination with pathogens, spoilage during conservation and allergies. Consumer attitude is a major issue in the Western world and a number of strategies are proposed to encourage insect consumption. We discuss research pathways to make insects a viable sector in food and agriculture: an appropriate disciplinary focus, quantifying its importance, comparing its nutritional value to conventional protein sources, environmental benefits, safeguarding food safety, optimising farming, consumer acceptance and gastronomy.

Bioavailability of Zinc in Wistar Rats Fed with Rice Fortified with Zinc Oxide

PubMed Central

Della Lucia, Ceres Mattos; Santos, Laura Luiza Menezes; Rodrigues, Kellen Cristina da Cruz; Rodrigues, Vivian Cristina da Cruz; Martino, Hércia Stampini Duarte; Pinheiro Sant’Ana, Helena Maria

2014-01-01

The study of zinc bioavailability in foods is important because this mineral intake does not meet the recommended doses for some population groups. Also, the presence of dietary factors that reduce zinc absorption contributes to its deficiency. Rice fortified with micronutrients (Ultra Rice®) is a viable alternative for fortification since this cereal is already inserted into the population habit. The aim of this study was to evaluate the bioavailability of zinc (Zn) in rice fortified with zinc oxide. During 42 days, rats were divided into four groups and fed with diets containing two different sources of Zn (test diet: UR® fortified with zinc oxide, or control diet: zinc carbonate (ZnCO3)), supplying 50% or 100%, respectively, of the recommendations of this mineral for animals. Weight gain, food intake, feed efficiency ratio, weight, thickness and length of femur; retention of zinc, calcium (Ca) and magnesium (Mg) in the femur and the concentrations of Zn in femur, plasma and erythrocytes were evaluated. Control diet showed higher weight gain, feed efficiency ratio, retention of Zn and Zn concentration in the femur (p < 0.05). However, no differences were observed (p > 0.05) for dietary intake, length and thickness of the femur, erythrocyte and plasmatic Zn between groups. Although rice fortified with zinc oxide showed a lower bioavailability compared to ZnCO3, this food can be a viable alternative to be used as a vehicle for fortification. PMID:24932657

Profile of bioactive compounds from grape pomace (Vitis vinifera and Vitis labrusca) by spectrophotometric, chromatographic and spectral analyses.

PubMed

Ribeiro, L F; Ribani, R H; Francisco, T M G; Soares, A A; Pontarolo, R; Haminiuk, C W I

2015-12-15

The aim of this study was to characterize grape pomace (GP) from winemaking byproducts of different grape samples (Cabernet Sauvignon-CS; Merlot-ME; Mix composed of 65% Bordeaux, 25% Isabel and 10% BRS Violet-MI and Terci-TE) with a view to exploiting its potential as a source of bioactive compounds and an alternative to the reuse of waste. Bioactive compounds such as individual phenolic compounds and polyunsaturated fatty acids (PUFA) were identified and quantified by spectrophotometric, chromatographic and spectral analyses. The sample of MI had the highest concentrations for total phenolic compounds and total flavonoids, while TE had the highest content for total monomeric anthocyanins. For all samples it was possible to identify 13 different anthocyanins by high performance liquid chromatography (HPLC) and mass spectrometry (MS). Moreover, the GP samples showed phenolic acids; flavan-3-ols such as catechin; flavonols such as quercetin, rutin and kaempferol; and stilbenes such as trans-resveratrol. Therefore, grape pomace can be considered a source for the recovery of phenolic compounds having antioxidant activity as well as a rich source of PUFA. Thus it can be used as an ingredient in the development of new food products, since it is suitable for human consumption, and a viable alternative both to adding nutritional value to food and to reduce environmental contamination. Copyright © 2015. Published by Elsevier B.V.

Alternative Donor Graft Sources for Adults with Hematologic Malignancies: A Donor for All Patients in 2017!

PubMed

Kindwall-Keller, Tamila L; Ballen, Karen K

2017-09-01

Hematopoietic stem cell transplant (HSCT) is potentially curative for a wide variety of malignant diseases, including acute and leukemias, lymphoma, and myelodysplasia. Choice of a stem cell donor is dependent on donor availability, donor compatibility and health, recipient disease type, and recipient condition. Current sources of stem cell donation for HSCT are matched sibling donors (MSDs), matched unrelated donors (MUDs), 1-antigen mismatched unrelated donors (MMUDs), haploidentical donors (haplo), and umbilical cord blood (UCB) units. Historically, preferred donors for HSCT have been human leukocyte antigen (HLA)-matched sibling donors; however, only about 30% of U.S. patients will have a MSD available. The majority of patients referred for HSCT will require an alternative donor graft: MUD, MMUD, UCB, or haplo. The likelihood of finding a MUD varies depending on the ethnicity of the recipient. White Caucasians of European descent have the greatest chance of finding a MUD. Chances of finding a MUD are significantly less for African-American or Hispanic recipients due to HLA polymorphisms. Therefore, MMUD, UCB, and haplo donor graft sources expand the donor pool for recipients who do not have a MSD or MUD available. Given the variety of different donor stem cell sources available today, nearly every patient who needs an allogeneic HSCT has a potential donor in 2017. All transplant-eligible patients with hematologic malignancies should be evaluated by a transplant center to determine if HSCT is a viable treatment option for their underlying disease process. The goal of this review is to increase the awareness of oncology practitioners to the availability of alternative donor stem cell transplants for patients with hematologic malignancies. Despite new agents, stem cell transplant remains the only curative therapy for many patients with acute and chronic leukemia, myelodysplasia, and lymphoma. Given the variety of different donor stem cell sources available today, nearly every patient who needs an allogeneic stem cell transplant will have a donor. © AlphaMed Press 2017.

Alternatives Analysis for the Resumption of Transient Testing Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee Nelson

2013-11-01

An alternatives analysis was performed for resumption of transient testing. The analysis considered eleven alternatives – including both US international facilities. A screening process was used to identify two viable alternatives from the original eleven. In addition, the alternatives analysis includes a no action alternative as required by the National Environmental Policy Act (NEPA). The alternatives considered in this analysis included: 1. Restart the Transient Reactor Test Facility (TREAT) 2. Modify the Annular Core Research Reactor (ACRR) which includes construction of a new hot cell and installation of a new hodoscope. 3. No Action

Job Sharing Provides a Useful Alternative.

ERIC Educational Resources Information Center

Plant, Sheila

1985-01-01

Job sharing is discussed as alternative approach to traditional professional librarian work arrangements and viable solution for: working mothers wanting part-time, career-oriented jobs; end-of-career librarians near retirement; those who desire increased leisure. Employers' reluctance is outlined noting increased expense, salary problems,…

Efficient photochemical generation of peroxycarboxylic nitric anhydrides with ultraviolet light-emitting diodes

NASA Astrophysics Data System (ADS)

Rider, N. D.; Taha, Y. M.; Odame-Ankrah, C. A.; Huo, J. A.; Tokarek, T. W.; Cairns, E.; Moussa, S. G.; Liggio, J.; Osthoff, H. D.

2015-07-01

Photochemical sources of peroxycarboxylic nitric anhydrides (PANs) are utilized in many atmospheric measurement techniques for calibration or to deliver an internal standard. Conventionally, such sources rely on phosphor-coated low-pressure mercury (Hg) lamps to generate the UV light necessary to photo-dissociate a dialkyl ketone (usually acetone) in the presence of a calibrated amount of nitric oxide (NO) and oxygen (O2). In this manuscript, a photochemical PAN source in which the Hg lamp has been replaced by arrays of ultraviolet light-emitting diodes (UV-LEDs) is described. The output of the UV-LED source was analyzed by gas chromatography (PAN-GC) and thermal dissociation cavity ring-down spectroscopy (TD-CRDS). Using acetone, diethyl ketone (DIEK), diisopropyl ketone (DIPK), or di-n-propyl ketone (DNPK), respectively, the source produces peroxyacetic (PAN), peroxypropionic (PPN), peroxyisobutanoic (PiBN), or peroxy-n-butanoic nitric anhydride (PnBN) from NO in high yield (> 90 %). Box model simulations with a subset of the Master Chemical Mechanism (MCM) were carried out to rationalize product yields and to identify side products. The present work demonstrates that UV-LED arrays are a viable alternative to current Hg lamp setups.

Influence of carbon sources on the viability and resuscitation of Acetobacter senegalensis during high-temperature gluconic acid fermentation.

PubMed

Shafiei, Rasoul; Zarmehrkhorshid, Raziyeh; Mounir, Majid; Thonart, Philippe; Delvigne, Frank

2017-05-01

Much research has been conducted about different types of fermentation at high temperature, but only a few of them have studied cell viability changes during high-temperature fermentation. In this study, Acetobacter senegalensis, a thermo-tolerant strain, was used for gluconic acid production at 38 °C. The influences of different carbon sources and physicochemical conditions on cell viability and the resuscitation of viable but nonculturable (VBNC) cells formed during fermentation were studied. Based on the obtained results, A. senegalensis could oxidize 95 g l - 1 glucose to gluconate at 38 °C (pH 5.5, yield 83%). However, despite the availability of carbon and nitrogen sources, the specific rates of glucose consumption (q s ) and gluconate production (q p ) reduced progressively. Interestingly, gradual q s and q p reduction coincided with gradual decrease in cellular dehydrogenase activity, cell envelope integrity, and cell culturability as well as with the formation of VBNC cells. Entry of cells into VBNC state during stationary phase partly stemmed from high fermentation temperature and long-term oxidation of glucose, because just about 48% of VBNC cells formed during stationary phase were resuscitated by supplementing the culture medium with an alternative favorite carbon source (low concentration of ethanol) and/or reducing incubation temperature to 30 °C. This indicates that ethanol, as a favorable carbon source, supports the repair of stressed cells. Since formation of VBNC cells is often inevitable during high-temperature fermentation, using an alternative carbon source together with changing physicochemical conditions may enable the resuscitation of VBNC cells and their use for several production cycles.

Television and Our Children. A Report of the Activities of the Alternatives in Children's Broadcasting Project.

ERIC Educational Resources Information Center

Mainse, David

Two major objectives of the Alternatives in Children's Broadcasting Project were to determine the extent of the influence of violence in children's television and to determine if children's interest in prosocial programming makes it a viable alternative to violence programming. Both adults and 8-10 year old children were surveyed about their…

On the self-serving function of an academic wooden leg: test anxiety as a self-handicapping strategy.

PubMed

Smith, C W; Snyder, D R; Handelsman, M M

1982-02-01

The present study investigated the hypothesis that psychological symptoms may serve a self-protective function by providing an alternative explanation for potential failure in evaluating situations. It was hypothesized that highly test-anxious subjects would report anxiety symptoms in a pattern that reflected strategic presentation of symptoms; more specifically, it was predicted that greater reported anxiety should result when anxiety was a viable explanation for poor performance on an intelligence test and that lower reported anxiety should result when anxiety was not a viable explanation for poor performance. Analysis of state measures of self-reported anxiety supported these predictions. Further analysis indicated that when anxiety was not a viable explanation for poor test performance, high test-anxiety subjects reported reduced effort as an alternative self-protective strategy. These results are discussed in terms of traditional models of symptoms as self-protective strategies, current social psychological models of symptoms, and in reference to recent theory and research about the nature and treatment of test anxiety.

A study of low-cost, robust assistive listening system (ALS) based on digital wireless technology.

PubMed

Israsena, P; Dubsok, P; Pan-Ngum, S

2008-11-01

We have developed a simple, low-cost digital wireless broadcasting system prototype, intended for a classroom of hearing impaired students. The system is designed to be a low-cost alternative to an existing FM system. The system implemented is for short-range communication, with a one-transmitter, multiple-receiver configuration, which is typical for these classrooms. The data is source-coded for voice-band quality, FSK modulated, and broadcasted via a 915 MHz radio frequency. A DES encryption can optionally be added for better information security. Test results show that the system operating range is approximately ten metres, and the sound quality is close to telephone quality as intended. We also discuss performance issues such as sound, power and size, as well as transmission protocols. The test results are the proof of concept that the prototype is a viable alternative to an existing FM system. Improvements can be made to the system's sound quality via techniques such as channel coding, which is also discussed.

Biochemical characteristics of four marine fish skins in Korea.

PubMed

Cho, Jae-Kwon; Jin, Young-Guk; Rha, Sung-Ju; Kim, Seon-Jae; Hwang, Jae-Ho

2014-09-15

In this study, we investigated the biochemical characteristics of the fish skins of four industrial species: olive flounder (Paralichthys olivaceus), black rockfish (Sebastes schlegeli), sea bass (Lateolabrax maculatus) and red sea bream (Pagrus major). There is high domestic demand in Korea for farming of these fish for human consumption. Crude protein contents in the skin of these fish ranged from 73% to 94% by dry weight; this was in part due to a high content of the structural protein, collagen. Among the four species, olive flounder had the thickest dermal and epidermal layers in the dorsal skin. This species was also associated with the highest extraction ratio of acid-soluble collagen. We also examined whether fish skin could be a cost-effective alternative to current fish meal sources. Our analysis indicates that, when supplemented with additional fish oils and essential amino acids, fish skin is a viable alternative for fish meal formulations. Copyright © 2014 Elsevier Ltd. All rights reserved.

Water-use data for the Red River of the North Basin, North Dakota, Minnesota, and South Dakota, 1979-2001

USGS Publications Warehouse

Macek-Rowland, Kathleen M.; Arntson, Allan D.; Ryberg, Karen R.; Dahl, Ann L.; Lieb, Amy

2004-01-01

The Red River of the North, located in the north-central plains of the United States, plays an important role in population growth and economic development of the region. Because of recent and projected growth in population, industry, and agriculture in the Red River of the North Basin, alternatives to additional water resources will be needed to supplement future water needs. Past and current water-use data are needed to help select the most viable water-resource alternatives. Withdrawal and return flow data were collected from various sources throughout the Red River of the North Basin from 1979 through 2001. The withdrawal data were aggregated by subbasin, monthly totals, and water-use categories. The return flow data were aggregated by subbasin and monthly totals. The Red River of the North Basin was divided into subbasins based on locations of U.S. Geological Survey streamflow-gaging stations and by specifically-identified reaches. Results of the water-use compilation are provided in this report.

Rethinking chiller plant design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meckler, M.

1998-07-01

While most refrigeration chillers operate today on electricity, the use of natural gas is becoming an increasingly attractive alternative. This is largely because electricity does not use energy very efficiency (because of transmission and combustion fuel losses), high demand charges, and the high incremental cost of electricity to operate chillers. The use of gas engine-driven chillers eliminates the high incremental cost of electricity. Additionally, gas engine-driven systems can operate with COPs up to 1.8 and, therefore, are economically viable alternatives. Recent advances in gas engine-driven and DFA absorption chillers, and in commercially viable solid and liquid desiccant-cooling systems, suggest amore » bright future for the gas industry. The use of such equipment in conjunction with or in place of commercially available electrical-powered alternatives can significantly impact demand-side management savings for utility ratepayers in the short run and provide significant hybrid opportunities for deregulated markets in the intermediate to long term.« less

Rethinking chiller plant design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meckler, M.

1998-01-01

While most refrigeration chillers operate today on electricity, the use of natural gas is becoming an increasingly attractive alternative. This is largely because electricity does not use energy very efficiently (due to transmission and combustion fuel losses), high demand charges, and the high incremental cost of electricity to operate chillers. The use of gas engine-driven chillers eliminates the high incremental cost of electricity. Additionally, gas engine-driven systems can operate with COPs up to 1.8 and therefore are economically viable alternatives. Recent advances in gas engine-driven and direct-fired absorption chillers and in commercially viable solid- and liquid-desiccant cooling systems suggest amore » bright future for the gas industry. The use of such equipment in conjunction with or in place of commercially available electrical-powered alternatives can significantly impact demand-side management savings for utility ratepayers in the short run and provide significant hybrid opportunities for deregulated markets in the intermediate to long term.« less

Satellite Power Systems (SPS) Concept Definition Study. Volume 1: Executive Summary

NASA Technical Reports Server (NTRS)

Hanley, G.

1978-01-01

The evolution of a total satellite power is described as well as major subsystem alternatives. Trade study results are given for satellite concepts, ground receiving antennas, satellite construction sites, and transportation. Point design definition, end-to-end analysis, and programmatics are covered. The GaAlAs photovoltaic concept is recommended as the current preliminary baseline satellite concept with silicon photovoltaic and Rankine cycle solar-thermal concepts as viable alternatives. Geosynchronous orbit is preferred for the construction of the satellite. A horizontal takeoff and landing air breathing rocket HLLV concept is preferred for earth-to-LEO transportation, with vertical takeoff options as viable alternatives. An argon electric orbit transfer vehicle is preferred for cargo transport from LEO and GEO orbit, and a chemical LH2/L02, two-stage orbit transfer vehicle is recommended for crew transport. A stripline rectenna array is the current preferred concept.

Alternative Pathways into University: Are Tertiary Preparation Programs a Viable Option?

ERIC Educational Resources Information Center

Chesters, Jenny; Rutter, Kerry; Nelson, Karen; Watson, Louis

2018-01-01

During the past three decades, the student populations of Australian universities have become more heterogeneous as the higher education sector expanded and new alternative entry pathways were established. Broadening access to university study and, therefore, to professional and semi-professional occupations, provides avenues for social mobility.…

Flue gas desulfurization gypsum: Its effectiveness as an alternative bedding material for broiler production

USDA-ARS?s Scientific Manuscript database

Flue gas desulfurization gypsum (FGDG) may be a viable low-cost alternative bedding material for broiler production. In order to evaluate FGD gypsum’s viability, three consecutive trials were conducted to determine its influence on live performance (body weight, feed consumption, feed efficiency, an...

Plants as sources of airborne bacteria, including ice nucleation-active bacteria.

PubMed

Lindemann, J; Constantinidou, H A; Barchet, W R; Upper, C D

1982-11-01

Vertical wind shear and concentration gradients of viable, airborne bacteria were used to calculate the upward flux of viable cells above bare soil and canopies of several crops. Concentrations at soil or canopy height varied from 46 colony-forming units per m over young corn and wet soil to 663 colony-forming units per m over dry soil and 6,500 colony-forming units per m over a closed wheat canopy. In simultaneous samples, concentrations of viable bacteria in the air 10 m inside an alfalfa field were fourfold higher than those over a field with dry, bare soil immediately upwind. The upward flux of viable bacteria over alfalfa was three- to fourfold greater than over dry soil. Concentrations of ice nucleation-active bacteria were higher over plants than over soil. Thus, plant canopies may constitute a major source of bacteria, including ice nucleation-active bacteria, in the air.

Photodynamic therapy as a new approach in vulvovaginal candidiasis in murine model

NASA Astrophysics Data System (ADS)

Santi, Maria E.; Lopes, Rubia G.; Prates, Renato A.; Sousa, Aline; Ferreira, Luis R.; Fernandes, Adjaci U.; Bussadori, Sandra K.; Deana, Alessandro M.

2015-02-01

Vulvovaginal candidiasis is a common cause of vaginal infections. This study investigates the efficiency of antimicrobial photodynamic therapy (aPDT) against yeast cells in mice. Methylene blue (MB), malachite green (MG), and a special designed protoporphirin (PpNetNI) were used as photosensitizers. Female BALB-c mice were infected with Candida albicans ATCC 90028. PDT was applied with two different light sources, intravaginal and transabdominal. Vaginal washes were performed and cultivated for microbial quantification. Antimicrobial PDT was able to decrease microbial content with MB and PpNetNI (p<0.05), it was not effective, however, with MG photosensitizer. The results of this study demonstrate that aPDT may be a viable alternative treatment for vaginal candidiasis.

An SCR inverter for electric vehicles

NASA Technical Reports Server (NTRS)

Latos, T.; Bosack, D.; Ehrlich, R.; Jahns, T.; Mezera, J.; Thimmesch, D.

1980-01-01

An inverter for an electric vehicle propulsion application has been designed and constructed to excite a polyphase induction motor from a fixed propulsion battery source. The inverter, rated at 35kW peak power, is fully regenerative and permits vehicle operation in both the forward and reverse directions. Thyristors are employed as the power switching devices arranged in a dc bus commutated topology. This paper describes the major role the controller plays in generating the motor excitation voltage and frequency to deliver performance similar to dc systems. Motoring efficiency test data for the controller are presented. It is concluded that an SCR inverter in conjunction with an ac induction motor is a viable alternative to present dc vehicle propulsion systems on the basis of performance and size criteria.

Open source tools for fluorescent imaging.

PubMed

Hamilton, Nicholas A

2012-01-01

As microscopy becomes increasingly automated and imaging expands in the spatial and time dimensions, quantitative analysis tools for fluorescent imaging are becoming critical to remove both bottlenecks in throughput as well as fully extract and exploit the information contained in the imaging. In recent years there has been a flurry of activity in the development of bio-image analysis tools and methods with the result that there are now many high-quality, well-documented, and well-supported open source bio-image analysis projects with large user bases that cover essentially every aspect from image capture to publication. These open source solutions are now providing a viable alternative to commercial solutions. More importantly, they are forming an interoperable and interconnected network of tools that allow data and analysis methods to be shared between many of the major projects. Just as researchers build on, transmit, and verify knowledge through publication, open source analysis methods and software are creating a foundation that can be built upon, transmitted, and verified. Here we describe many of the major projects, their capabilities, and features. We also give an overview of the current state of open source software for fluorescent microscopy analysis and the many reasons to use and develop open source methods. Copyright © 2012 Elsevier Inc. All rights reserved.

Proteins for breaking barriers in lignocellulosic bioethanol production.

PubMed

Ulaganathan, Kandasamy; Goud, Burragoni S; Reddy, Mettu M; Kumar, Vanaparthi P; Balsingh, Jatoth; Radhakrishna, Surabhi

2015-01-01

Reduction in fossil fuel consumption by using alternate sources of energy is a major challenge facing mankind in the coming decades. Bioethanol production using lignocellulosic biomass is the most viable option for addressing this challenge. Industrial bioconversion of lignocellulosic biomass, though possible now, is not economically viable due to presence of barriers that escalate the cost of production. As cellulose and hemicellulose are the major constituents of terrestrial biomass, which is available in massive quantities, hydrolysis of cellulose and hemicellulose by the microorganisms are the most prominent biochemical processes happening in the earth. Microorganisms possess different categories of proteins associated with different stages of bioethanol production and a number of them are already found and characterized. Many more of these proteins need to be identified which suit the specificities needed for the bioethanol production process. Discovery of proteins with novel specificities and application of genetic engineering technologies to harvest the synergies existing between them with the aim to develop consolidated bioprocess is the major direction of research in the future. In this review, we discuss the different categories of proteins used for bioethanol production in the context of breaking the barriers existing for the economically feasible lignocellulosic bioethanol production.

Physiology limits commercially viable photoautotrophic production of microalgal biofuels.

PubMed

Kenny, Philip; Flynn, Kevin J

2017-01-01

Algal biofuels have been offered as an alternative to fossil fuels, based on claims that microalgae can provide a highly productive source of compounds as feedstocks for sustainable transport fuels. Life cycle analyses identify algal productivity as a critical factor affecting commercial and environmental viability. Here, we use mechanistic modelling of the biological processes driving microalgal growth to explore optimal production scenarios in an industrial setting, enabling us to quantify limits to algal biofuels potential. We demonstrate how physiological and operational trade-offs combine to restrict the potential for solar-powered algal-biodiesel production in open ponds to a ceiling of ca. 8000 L ha -1 year -1 . For industrial-scale operations, practical considerations limit production to ca. 6000 L ha -1 year -1 . According to published economic models and life cycle analyses, such production rates cannot support long-term viable commercialisation of solar-powered cultivation of natural microalgae strains exclusively as feedstock for biofuels. The commercial viability of microalgal biofuels depends critically upon limitations in microalgal physiology (primarily in rates of C-fixation); we discuss the scope for addressing this bottleneck concluding that even deployment of genetically modified microalgae with radically enhanced characteristics would leave a very significant logistical if not financial burden.

Energy scavenging sources for biomedical sensors.

PubMed

Romero, E; Warrington, R O; Neuman, M R

2009-09-01

Energy scavenging has increasingly become an interesting option for powering electronic devices because of the almost infinite lifetime and the non-dependence on fuels for energy generation. Moreover, the rise of wireless technologies promises new applications in medical monitoring systems, but these still face limitations due to battery lifetime and size. A trade-off of these two factors has typically governed the size, useful life and capabilities of an autonomous system. Energy generation from sources such as motion, light and temperature gradients has been established as commercially viable alternatives to batteries for human-powered flashlights, solar calculators, radio receivers and thermal-powered wristwatches, among others. Research on energy harvesting from human activities has also addressed the feasibility of powering wearable or implantable systems. Biomedical sensors can take advantage of human-based activities as the energy source for energy scavengers. This review describes the state of the art of energy scavenging technologies for powering sensors and instrumentation of physiological variables. After a short description of the human power and the energy generation limits, the different transduction mechanisms, recent developments and challenges faced are reviewed and discussed.

Philanthropy as a source of funding for nursing initiatives.

PubMed

Kleinpell, Ruth M; Start, Rachel; McIntosh, Erik; Worobec, Sophia; Llewellyn, Jane

2014-01-01

Nurse leaders are challenged with ensuring that research and evidence-based practices are being integrated into clinical care. Initiatives such as the Magnet Recognition Program have helped reinforce the importance of advancing nursing practices to integrate best practices, conduct quality improvement initiatives, improve performance metrics, and involve bedside nurses in conducting research and evidence-based practice projects. While seeking research funding is an option for some initiatives, other strategies such as seeking funding from grateful patients or from philanthropic resources are becoming important options for nurse leaders to pursue, as the availability of funding from traditional sources such as professional organizations or federal funding becomes more limited. In addition, more institutions are seeking and applying for funding, increasing the pool of candidates who are vying for existing funding. Seeking alternative sources of funding, such as through philanthropy, becomes a viable option. This article reviews important considerations in seeking funding from philanthropic sources for nursing initiatives. Examples from a multiyear project that focused on promoting a healthy work environment and improving nursing morale are used to highlight strategies that were used to solicit, obtain, and secure extension funding from private foundation funding to support the initiative.

Joint Source-Channel Decoding of Variable-Length Codes with Soft Information: A Survey

NASA Astrophysics Data System (ADS)

Guillemot, Christine; Siohan, Pierre

2005-12-01

Multimedia transmission over time-varying wireless channels presents a number of challenges beyond existing capabilities conceived so far for third-generation networks. Efficient quality-of-service (QoS) provisioning for multimedia on these channels may in particular require a loosening and a rethinking of the layer separation principle. In that context, joint source-channel decoding (JSCD) strategies have gained attention as viable alternatives to separate decoding of source and channel codes. A statistical framework based on hidden Markov models (HMM) capturing dependencies between the source and channel coding components sets the foundation for optimal design of techniques of joint decoding of source and channel codes. The problem has been largely addressed in the research community, by considering both fixed-length codes (FLC) and variable-length source codes (VLC) widely used in compression standards. Joint source-channel decoding of VLC raises specific difficulties due to the fact that the segmentation of the received bitstream into source symbols is random. This paper makes a survey of recent theoretical and practical advances in the area of JSCD with soft information of VLC-encoded sources. It first describes the main paths followed for designing efficient estimators for VLC-encoded sources, the key component of the JSCD iterative structure. It then presents the main issues involved in the application of the turbo principle to JSCD of VLC-encoded sources as well as the main approaches to source-controlled channel decoding. This survey terminates by performance illustrations with real image and video decoding systems.

Hermeneutic-Narrative Approach to Career Counselling: An Alternative to Postmodernism

ERIC Educational Resources Information Center

Thrif, Erin; Amundson, Norman

2005-01-01

Postmodern approaches to career counselling have been suggested as a viable alternative to traditional career theories that rely on modernist assumptions. However, some of the assumptions that underlie postmodernism may prove to be unhelpful to career development practice in the long run. In this article we examine critiques of postmodern…

Application of the Cross Battery Approach in the Assessment of American Indian Children: A Viable Alternative.

ERIC Educational Resources Information Center

Plank, Gary A.

2001-01-01

Current psychometric and testing practices are inadequate for assessing the intelligence of American Indian students, due to complicating factors of culture and language. These deficient methods are then used to make educational decisions, resulting in improper special education placements. The benefits of alternative methods of testing, including…

DEMONSTRATION OF N-METHYL PYRROLIDONE (NMP) AS A POLLUTION PREVENTION ALTERNATIVE TO PAINT STRIPPING WITH METHYLENE CHLORIDE

EPA Science Inventory

This objective of this paper is to demonstrate that NMP is a viable pollution prevention alternative to methylene chloride. Maine Corps Logistics Base (MCLB), Albany, GA, USA was the host site for the demonstration. MCLB's primary function is maintenance of military ground supp...

What Does Galileo's Discovery of Jupiter's Moons Tell Us about the Process of Scientific Discovery?

ERIC Educational Resources Information Center

Lawson, Anton E.

2002-01-01

Given that hypothetico-deductive reasoning has played a role in other important scientific discoveries, asks the question whether it plays a role in all important scientific discoveries. Explores and rejects as viable alternatives possible alternative scientific methods such as Baconian induction and combinatorial analysis. Discusses the…

A review on technological options of waste to energy for effective management of municipal solid waste.

PubMed

Kumar, Atul; Samadder, S R

2017-11-01

Approximately one-fourth population across the world rely on traditional fuels (kerosene, natural gas, biomass residue, firewood, coal, animal dung, etc.) for domestic use despite significant socioeconomic and technological development. Fossil fuel reserves are being exploited at a very fast rate to meet the increasing energy demands, so there is a need to find alternative sources of energy before all the fossil fuel reserves are depleted. Waste to energy (WTE) can be considered as a potential alternative source of energy, which is economically viable and environmentally sustainable. The present study reviewed the current global scenario of WTE technological options (incineration, pyrolysis, gasification, anaerobic digestion, and landfilling with gas recovery) for effective energy recovery and the challenges faced by developed and developing countries. This review will provide a framework for evaluating WTE technological options based on case studies of developed and developing countries. Unsanitary landfilling is the most commonly practiced waste disposal option in the developing countries. However, developed countries have realised the potential of WTE technologies for effective municipal solid waste management (MSWM). This review will help the policy makers and the implementing authorities involved in MSWM to understand the current status, challenges and barriers for effective management of municipal solid waste. This review concluded WTE as a potential renewable source of energy, which will partly meet the energy demand and ensure effective MSWM. Copyright © 2017 Elsevier Ltd. All rights reserved.

Alternatives to Testosterone Therapy: A Review.

PubMed

Lo, Eric M; Rodriguez, Katherine M; Pastuszak, Alexander W; Khera, Mohit

2018-01-01

Although testosterone therapy (TTh) is an effective treatment for hypogonadism, recent concerns regarding its safety have been raised. In 2015, the US Food and Drug Administration issued a warning about potential cardiovascular risks resulting from TTh. Fertility preservation is another reason to search for viable alternative therapies to conventional TTh, and in this review we evaluate the literature examining these alternatives. To review the role and limitations of non-testosterone treatments for hypogonadism. A literature search was conducted using PubMed to identify relevant studies examining medical and non-medical alternatives to TTh. Search terms included hypogonadism, testosterone replacement therapy, testosterone therapy, testosterone replacement alternatives, diet and exercise and testosterone, varicocele repair and testosterone, stress reduction and testosterone, and sleep apnea and testosterone. Review of peer-reviewed literature. Medical therapies examined include human chorionic gonadotropins, aromatase inhibitors, and selective estrogen receptor modulators. Non-drug therapies that are reviewed include lifestyle modifications including diet and exercise, improvements in sleep, decreasing stress, and varicocele repair. The high prevalence of obesity and metabolic syndrome in the United States suggests that disease modification could represent a viable treatment approach for affected men with hypogonadism. These alternatives to TTh can increase testosterone levels and should be considered before TTh. Lo EM, Rodriguez KM, Pastuszak AW, Khera M. Alternatives to Testosterone Therapy: A Review. Sex Med Rev 2018;6:106-113. Copyright © 2017. Published by Elsevier Inc.

Development of nanomaterial-enabled advanced oxidation techniques for treatment of organic micropollutants

NASA Astrophysics Data System (ADS)

Oulton, Rebekah Lynn

Increasing demand for limited fresh water resources necessitates that alternative water sources be developed. Nonpotable reuse of treated wastewater represents one such alternative. However, the ubiquitous presence of organic micropollutants such as pharmaceuticals and personal care products (PPCPs) in wastewater effluents limits use of this resource. Numerous investigations have examined PPCP fate during wastewater treatment, focusing on their removal during conventional and advanced treatment processes. Analysis of influent and effluent data from published studies reveals that at best 1-log10 concentration unit of PPCP removal can generally be achieved with conventional treatment. In contrast, plants employing advanced treatment methods, particularly ozonation and/or membranes, remove most PPCPs often to levels below analytical detection limits. However, membrane treatment is cost prohibitive for many facilities, and ozone treatment can be very selective. Ozone-recalcitrant compounds require the use of Advanced Oxidation Processes (AOPs), which utilize highly reactive hydroxyl radicals (*OH) to target resistant pollutants. Due to cost and energy use concerns associated with current AOPs, alternatives such as catalytic ozonation are under investigation. Catalytic ozonation uses substrates such as activated carbon to promote *OH formation during ozonation. Here, we show that multi-walled carbon nanotubes (MWCNTs) represent another viable substrate, promoting *OH formation during ozonation to levels exceeding activated carbon and equivalent to conventional ozone-based AOPs. Via a series of batch reactions, we observ a strong correlation between *OH formation and MWCNT surface oxygen concentrations. Results suggest that deprotonated carboxyl groups on the CNT surface are integral to their reactivity toward ozone and corresponding *OH formation. From a practical standpoint, we show that industrial grade MWCNTs exhibit similar *OH production as their research-grade counterparts. Accelerated aging studies indicate that MWCNTs maintain surface reactivity for an extended period during ozonation treatment. Further, *OH generation is essentially unaffected in complex water matrices containing known radical scavengers, and is effective for degradation of the ozone-recalcitrant herbicide atrazine. A proof-of-concept study verified that results from batch systems can be replicated in a flow-through reactor utilizing MWCNTs immobilized on a ceramic membrane support. Collective, results suggest that CNT-enhanced ozonation may provide a viable treatment alternative for emerging organic micropollutants.

Microbial response to triepthylphosphate

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hazen, T.C.; Santo Domingo, J.W.; Berry, C.J.

1997-05-01

The effect of triethylphosphate (TEP) on the activity of a landfill aquifer microbial community was evaluated using standard techniques and in situ hybridizations with phylogenetic probes. Benzene was used as an external carbon source to monitor degradation of an aromatic compound in TEP amended microcosms. Microscopical and viable counts were higher in TEP containing microcosms when compared to unamended controls. A significant increase in metabolic activity was also observed for TEP amended samples as determined by the number of cells hybridizing to an eubacterial probe. In addition, the number of beta and gamma Proteobacteria increased from undetectable levels prior tomore » the study to 15-29% of the total bacteria in microcosms containing TEP and benzene. In these microcosms, nearly 40% of the benzene was degraded during the incubation period compared to less than 5% in unamended microcosms. While TEP has previously been used as an alternate phosphate source in the bioremediation of chlorinated aliphatics, this study shows that it can also stimulate the microbial degradation of aromatics in phosphate limited aquifers.« less

Optimized x-ray source scanning trajectories for iterative reconstruction in high cone-angle tomography

NASA Astrophysics Data System (ADS)

Kingston, Andrew M.; Myers, Glenn R.; Latham, Shane J.; Li, Heyang; Veldkamp, Jan P.; Sheppard, Adrian P.

2016-10-01

With the GPU computing becoming main-stream, iterative tomographic reconstruction (IR) is becoming a com- putationally viable alternative to traditional single-shot analytical methods such as filtered back-projection. IR liberates one from the continuous X-ray source trajectories required for analytical reconstruction. We present a family of novel X-ray source trajectories for large-angle CBCT. These discrete (sparsely sampled) trajectories optimally fill the space of possible source locations by maximising the degree of mutually independent information. They satisfy a discrete equivalent of Tuy's sufficiency condition and allow high cone-angle (high-flux) tomog- raphy. The highly isotropic nature of the trajectory has several advantages: (1) The average source distance is approximately constant throughout the reconstruction volume, thus avoiding the differential-magnification artefacts that plague high cone-angle helical computed tomography; (2) Reduced streaking artifacts due to e.g. X-ray beam-hardening; (3) Misalignment and component motion manifests as blur in the tomogram rather than double-edges, which is easier to automatically correct; (4) An approximately shift-invariant point-spread-function which enables filtering as a pre-conditioner to speed IR convergence. We describe these space-filling trajectories and demonstrate their above-mentioned properties compared with a traditional helical trajectories.

Alternatives to clearcutting of old growth in southeast Alaska.

Treesearch

Sally. Duncan

1999-01-01

This issue of Science Findings examines the results of a study designed to provide a broad array of silvicultural options for land managers. Pacific Northwest Research Station scientist Mike McClellan is leading the study and has found that timber harvesting by using alternatives to clearcutting is viable in the current marketplace and technically feasible across a...

Does Teaching Experience Matter? Examining Biology Teachers' Prior Knowledge for Teaching in an Alternative Certification Program

ERIC Educational Resources Information Center

Friedrichsen, Patricia J.; Abell, Sandra K.; Pareja, Enrique M.; Brown, Patrick L.; Lankford, Deanna M.; Volkmann, Mark J.

2009-01-01

Alternative certification programs (ACPs) have been proposed as a viable way to address teacher shortages, yet we know little about how teacher knowledge develops within such programs. The purpose of this study was to investigate prior knowledge for teaching among students entering an ACP, comparing individuals with teaching experience to those…

Evolution of β-Cell Replacement Therapy in Diabetes Mellitus: Islet Cell Transplantation

PubMed Central

Jahansouz, Cyrus; Jahansouz, Cameron; Kumer, Sean C.; Brayman, Kenneth L.

2011-01-01

Diabetes mellitus remains one of the leading causes of morbidity and mortality worldwide. According to the Centers for Disease Control and Prevention, approximately 23.6 million people in the United States are affected. Of these individuals, 5 to 10% have been diagnosed with Type 1 diabetes mellitus (T1DM), an autoimmune disease. Although it often appears in childhood, T1DM may manifest at any age, leading to significant morbidity and decreased quality of life. Since the 1960s, the surgical treatment for diabetes mellitus has evolved to become a viable alternative to insulin administration, beginning with pancreatic transplantation. While islet cell transplantation has emerged as another potential alternative, its role in the treatment of T1DM remains to be solidified as research continues to establish it as a truly viable alternative for achieving insulin independence. In this paper, the historical evolution, procurement, current status, benefits, risks, and ongoing research of islet cell transplantation are explored. PMID:22013505

Evaluating the sustainability of an energy supply system using renewable energy sources: An energy demand assessment of South Carolina

NASA Astrophysics Data System (ADS)

Green, Cedric Fitzgerald

Sustainable energy is defined as a dynamic harmony between the equitable availability of energy-intensive goods and services to all people and the preservation of the earth for future generations. Sustainable energy development continues to be a major focus within the government and regulatory governing bodies in the electric utility industry. This is as a result of continued demand for electricity and the impact of greenhouse gas emissions from electricity generating plants on the environment by way of the greenhouse effect. A culmination of increasing concerns about climate change, the nuclear incident in Fukushima four years ago, and discussions on energy security in a world with growing energy demand have led to a movement for increasing the share of power generation from renewable energy sources. This work studies demand for electricity from primarily residential, commercial, agricultural, and industrial customers in South Carolina (SC) and its effect on the environment from coal-fired electricity generating plants. Moreover, this work studies sustainable renewable energy source-options based on the renewable resources available in the state of SC, as viable options to supplement generation from coal-fired electricity generating plants. In addition, greenhouse gas emissions and other pollutants from primarily coal-fired plants will be defined and quantified. Fundamental renewable energy source options will be defined and quantified based on availability and sustainability of SC's natural resources. This work studies the environmental, economic, and technical aspects of each renewable energy source as a sustainable energy option to replace power generation from coal-fired plants. Additionally, social aspect implications will be incorporated into each of the three aspects listed above, as these aspects are explored during the research and analysis. Electricity demand data and alternative energy source-supply data in SC are carried out and are used to develop and run the Sustainable Systems Analysis Algorithm (SSAA) and the multi-criteria decision analysis (MCDA) decision models. The following alternative energy sources for electricity (kilo- and megawatt output) will be assessed in this paper: solar, biomass and biofuels, hydro, geothermal, onshore wind, offshore wind, tidal, and natural gas. The SSAA methodology, in conjunction with the MCDA model techniques, will be used to obtain sustainable, alternative energy source system options; the system will attempt to balance its three linked aspects (environmental, economic, and technical). The results, based on the Sustainability Directive three-dimensional vector calculations from each alternative energy source option, are presented in this paper. Moving towards sustainability is a dynamically changing process, and the SSAA methodology is a synergist for system modifications that strives for continuous improvement toward the Ideal Sustainability Directive.

Efficacy of Diverse Antiparasitic Treatments for Cysticercosis in the Pig Model

PubMed Central

Gonzalez, Armando E.; Bustos, Javier A.; Jimenez, Juan A.; Rodriguez, Mary L.; Ramirez, Mercy G.; Gilman, Robert H.; Garcia, Hector H.

2012-01-01

Taenia solium cysticercosis infects pigs and humans. Because antiparasitic treatment for human cysticercosis has sub-optimal efficacy, alternative regimes are needed. Seven antiparasitic regimens were tested in 42 naturally infected pigs with cysticercosis, and compared with prednisone alone (n = 6) or no treatment (n = 6). The numbers of viable cysts in muscles and in the brain were examined after necropsy and were significantly decreased in pigs receiving combined albendazole plus praziquantel, albendazole alone, or oxfendazole. Pigs receiving praziquantel alone and nitazoxanide had numerous surviving cysts. Control (untreated) pigs and prednisone-treated pigs had many more viable cysts, suggesting no effect. Combined albendazole plus praziquantel, and oxfendazole, showed a strong cysticidal effect and provide suitable alternative treatments to be further explored for their use for treatment of human neurocysticercosis. PMID:22855760

Protein engineering in designing tailored enzymes and microorganisms for biofuels production

PubMed Central

Wen, Fei; Nair, Nikhil U; Zhao, Huimin

2009-01-01

Summary Lignocellulosic biofuels represent a sustainable, renewable, and the only foreseeable alternative energy source to transportation fossil fuels. However, the recalcitrant nature of lignocellulose poses technical hurdles to an economically viable biorefinery. Low enzymatic hydrolysis efficiency and low productivity, yield, and titer of biofuels are among the top cost contributors. Protein engineering has been used to improve the performances of lignocellulose-degrading enzymes, as well as proteins involved in biofuel synthesis pathways. Unlike its great success seen in other industrial applications, protein engineering has achieved only modest results in improving the lignocellulose-to-biofuels efficiency. This review will discuss the unique challenges that protein engineering faces in the process of converting lignocellulose to biofuels and how they are addressed by recent advances in this field. PMID:19660930

Biodiesel production and Environmental CO2 cleanup using Oleaginous Microorganisms from Al-Hassa area in Saudi Arabia

NASA Astrophysics Data System (ADS)

El-Sinawi, Abdulaziz; Shathele, Mohammad

2014-12-01

Biodiesel production is rapidly moving towards the mainstream as an alternative source of energy. Algae oil is one of the viable feed stocks among others to produce Biodiesel. However the difficulties in efficient biodiesel production from algae lie not in the extraction of the oil, but in finding an algal strain with a high lipid content and fast growth rate. This paper presents an experimental work performed to study the production of biodiesel from local algae strains in Al-Hassa territory of the eastern province in Saudi Arabia which was found to contain high lipid contents and show rapid growth. The collected results predict that those types of desert algae are promising and are considered to be a potential feedstock for biofuels.

An economic analysis of alternative paving materials

NASA Astrophysics Data System (ADS)

Mustain, J. L.

1982-12-01

The purpose of this paper is to present a means for economic analysis of alternative equivalent pavement designs, considering such factors as initial construction cost, annual maintenance cost, salvage value and the various intangibles which occur during the analysis period. Having established a means of economic comparison, it is then the intent of this paper to show that Portland Cement Concrete has been and is a viable pavement alternative and ought to receive due consideration in the military construction program.

The Role of Inverse Compton Scattering in Solar Coronal Hard X-Ray and γ-Ray Sources

NASA Astrophysics Data System (ADS)

Chen, Bin; Bastian, T. S.

2012-05-01

Coronal hard X-ray (HXR) and continuum γ-ray sources associated with the impulsive phase of solar flares have been the subject of renewed interest in recent years. They have been interpreted in terms of thin-target, non-thermal bremsstrahlung emission. This interpretation has led to rather extreme physical requirements in some cases. For example, in one case, essentially all of the electrons in the source must be accelerated to non-thermal energies to account for the coronal HXR source. In other cases, the extremely hard photon spectra of the coronal continuum γ-ray emission suggest that the low-energy cutoff of the electron energy distribution lies in the MeV energy range. Here, we consider the role of inverse Compton scattering (ICS) as an alternate emission mechanism in both the ultra- and mildly relativistic regimes. It is known that relativistic electrons are produced during powerful flares; these are capable of upscattering soft photospheric photons to HXR and γ-ray energies. Previously overlooked is the fact that mildly relativistic electrons, generally produced in much greater numbers in flares of all sizes, can upscatter extreme-ultraviolet/soft X-ray photons to HXR energies. We also explore ICS on anisotropic electron distributions and show that the resulting emission can be significantly enhanced over an isotropic electron distribution for favorable viewing geometries. We briefly review results from bremsstrahlung emission and reconsider circumstances under which non-thermal bremsstrahlung or ICS would be favored. Finally, we consider a selection of coronal HXR and γ-ray events and find that in some cases the ICS is a viable alternative emission mechanism.

Photoactivated methods for enabling cartilage-to-cartilage tissue fixation

NASA Astrophysics Data System (ADS)

Sitterle, Valerie B.; Roberts, David W.

2003-06-01

The present study investigates whether photoactivated attachment of cartilage can provide a viable method for more effective repair of damaged articular surfaces by providing an alternative to sutures, barbs, or fibrin glues for initial fixation. Unlike artificial materials, biological constructs do not possess the initial strength for press-fitting and are instead sutured or pinned in place, typically inducing even more tissue trauma. A possible alternative involves the application of a photosensitive material, which is then photoactivated with a laser source to attach the implant and host tissues together in either a photothermal or photochemical process. The photothermal version of this method shows potential, but has been almost entirely applied to vascularized tissues. Cartilage, however, exhibits several characteristics that produce appreciable differences between applying and refining these techniques when compared to previous efforts involving vascularized tissues. Preliminary investigations involving photochemical photosensitizers based on singlet oxygen and electron transfer mechanisms are discussed, and characterization of the photodynamic effects on bulk collagen gels as a simplified model system using FTIR is performed. Previous efforts using photothermal welding applied to cartilaginous tissues are reviewed.

Integrated system of phytodepuration and water reclamation: A comparative evaluation of four municipal wastewater treatment plants.

PubMed

Petroselli, Andrea; Giannotti, Maurizio; Marras, Tatiana; Allegrini, Elena

2017-06-03

In dry regions, water resources have become increasingly limited, and the use of alternative sources is considered one of the main strategies in sustainable water management. A highly viable alternative to commonly used water resources is treated municipal wastewater, which could strongly benefit from advanced and low-cost techniques for depuration, such as the integrated system of phytodepuration (ISP). The current manuscript investigates four Italian case studies with different sizes and characteristics. The raw wastewaters and final effluents were sampled on a monthly basis over a period of up to five years, allowing the quantification of the ISP performances. The results obtained show that the investigated plants are characterized by an average efficiency value of approximately 83% for chemical oxygen demand removal, 84% for biochemical oxygen demand, 89% for total nitrogen, 91% for total phosphorus, and 85% for total suspended solids. Moreover, for three of the case studies, the ISP final effluent is suitable for irrigation, and in the fourth case study, the final effluent can be released in surface water.

Can I Choose to Have Grit? Non-Cognitive Skills, Behavior, and School Choice

ERIC Educational Resources Information Center

Nichols, Malachi

2017-01-01

With the introduction of school choice as a viable option of school reform, researchers have begun to look beyond academic achievement to the effects of choice on alternative outcomes. Recently, non-cognitive skills and behavior stand at the front of those alternative outcomes. From the most up to date relevant literature it appears that school…

Does natural honey act as an alternative to antibiotics in the semen extender for cryopreservation of crossbred ram semen?

PubMed Central

Banday, M. N.; Lone, F. A.; Rasool, F.; Rather, H. A.; Rather, M. A.

2017-01-01

Antibiotics are added to semen extenders to take care of heavy microbial load, however, their continuous use poses a constant threat of developing antibiotic resistance by the common microbes present in the semen. Our hypothesis was that natural honey, having antibacterial activity and rich in fructose could replace the use of antibiotics and fructose in the semen extender. Twenty-four ejaculates from six crossbred rams were obtained and extended with tris-based extender without (control) and with honey at 2.5% (T1), 5% (T2) and 7% (T3). Sperm quality was measured in terms of percentage sperm motility, live sperm count, intact acrosome and hypo-osmotic swelling test (HOST) reacted spermatozoa. The semen samples at post-thaw were also evaluated for total viable count (colony forming units/ml). At post-thaw, control exhibited significantly (P<0.05) higher sperm motility in comparison to T2 and T3. The percent of live sperm count, intact acrosome and HOST reacted spermatozoa were significantly higher (P<0.05) for control than all other treatment groups at post-thaw. Among treatment groups, T1 maintained significantly higher (P<0.05) percentage of live sperm count, intact acrosome and HOST reacted spermatozoa than T2 and T3. The total viable count at post-thaw was significantly lower (P<0.05) for control than all the treatment groups. In conclusion, honey cannot be used as an alternative to antibiotics to take care of heavy microbial load in semen, however, levels up to 2.5% may be supplemented to semen as an energy source. PMID:29387098

Stability, antimicrobial activity, and effect of nisin on the physico-chemical properties of fruit juices.

PubMed

de Oliveira Junior, Adelson Alves; de Araújo Couto, Hyrla Grazielle Silva; Barbosa, Ana Andréa Teixeira; Carnelossi, Marcelo Augusto Guitierrez; de Moura, Tatiana Rodrigues

2015-10-15

Heat processing is the most commonly used hurdle for inactivating microorganisms in fruit juices. However, this preservation method could interfere with the organoleptic characteristics of the product. Alternative methods have been proposed and bacteriocins such as nisin are potential candidates. However, the approval of bacteriocins as food additives is limited, especially in foods from vegetal origin. We aimed to verify the stability, the effect on physico-chemical properties, and the antimicrobial activity of nisin in different fruit juices. Nisin remained stable in fruit juices (cashew, soursop, peach, mango, passion fruit, orange, guava, and cupuassu) for at least 30 days at room or refrigerated temperature and did not cause any significant alterations in the physico-chemical characteristics of the juices. Besides, nisin favored the preservation of vitamin C content in juices. The antimicrobial activity of nisin was tested against Alicyclobacillus acidoterrestris, Bacillus cereus, Staphylococcus aureus and Listeria monocytogenes in cashew, soursop, peach, and mango juices. Nisin caused a 4-log reduction in viable cells of A. acidoterrestris in soursop, peach, and mango juices after 8h of incubation, and no viable cells were detected in cashew juices. After 24h of incubation in the presence of nisin, no viable cells were detected, independently of the juices. To S. aureus, at 24h of incubation in the presence of nisin, viable cells were only detected in mango juices, representing a 4-log decrease as compared with the control treatment. The number of viable cells of B. cereus at 24h of incubation in the presence of nisin represented at least a 4-log decrease compared to the control treatment. When the antimicrobial activity of nisin was tested against L. monocytogenes in cashew and soursop juices, no reduction in the viable cell number was observed compared to the control treatment after 24h of incubation. Viable cells were four and six times less than in the control treatment, in peach and mango juices respectively. The most sensitive microorganism to nisin was A. acidoterrestris and the least sensitive was L. monocytogenes. Still, a reduction of up to 90% of viable cells was observed in peach and mango juices inoculated with L. monocytogenes. These results indicate that the use of nisin could be an alternative in fruit juice processing. Copyright © 2015 Elsevier B.V. All rights reserved.

Towards viable drinking water services.

PubMed

Hukka, J J; Katko, T S

1997-01-01

This article offers a framework for developing viable drinking water services and institutional development in developing countries. The framework evolved from the authors' research and field experience in transition and developing economies. Viability is related to operative technology, appropriate organizations, and adequate cost recovery within the context of water resources, human and economic resources, sociocultural conditions, and other constraints. The ability of institutions to solve the problems of coordination and production depends upon player motivation, the complexity of the environment, and the ability of the players to control the environment. Third party enforcement of agreements are essential to reduce gains from opportunism, cheating, and shirking. Empirical research finds that per capita water production costs are 4 times higher in centralized systems and lowest in decentralized systems with coordination from a central party. Three-tiered systems of governments, regulators, and service providers are recommended. Management options must be consumer driven. The worst case scenario is consumer's reliance on vending and reselling with no alternative source of supply. Policies should have a strong focus on institutional reforms in the water sector, the development of a consumer driven water sector, facilitation of appropriate private-public partnerships, sound management of existing capital assets, a system for building viability into national strategies for the water sector, and financially self-sufficient and consumer responsible water supply organizations.

Alternative general-aircraft engines

NASA Technical Reports Server (NTRS)

Tomazic, W. A.

1976-01-01

The most promising alternative engine (or engines) for application to general aircraft in the post-1985 time period was defined, and the level of technology was cited to the point where confident development of a new engine can begin early in the 1980's. Low emissions, multifuel capability, and fuel economy were emphasized. Six alternative propulsion concepts were considered to be viable candidates for future general-aircraft application: the advanced spark-ignition piston, rotary combustion, two- and four-stroke diesel, Stirling, and gas turbine engines.

Alternative-fueled truck demonstration natural gas program: Caterpillar G3406LE development and demonstration

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

In 1990, the California Energy Commission, the South Coast Air Quality Management District, and the Southern California Gas Company joined together to sponsor the development and demonstration of compressed natural gas engines for Class 8 heavy-duty line-haul trucking applications. This program became part of an overall Alternative-Fueled Truck Demonstration Program, with the goal of advancing the technological development of alternative-fueled engines. The demonstration showed natural gas to be a technically viable fuel for Class 8 truck engines.

Guest Comment: Universal Language Requirement.

ERIC Educational Resources Information Center

Sherwood, Bruce Arne

1979-01-01

Explains that reading English among Scientists is almost universal, however, there are enormous problems with spoken English. Advocates the use of Esperanto as a viable alternative, and as a language requirement for graduate work. (GA)

Cognitive Theory within the Framework of an Information Processing Model and Learning Hierarchy: Viable Alternative to the Bloom-Mager System.

ERIC Educational Resources Information Center

Stahl, Robert J.

This review of the current status of the human information processing model presents the Stahl Perceptual Information Processing and Operations Model (SPInPrOM) as a model of how thinking, memory, and the processing of information take place within the individual learner. A related system, the Domain of Cognition, is presented as an alternative to…

Self-interested agents create, maintain, and modify group-functional culture.

PubMed

Singh, Manvir; Glowacki, Luke; Wrangham, Richard W

2016-01-01

We agree that institutions and rules are crucial for explaining human sociality, but we question the claim of there not being "alternatives to CGS [that] can easily account for the institutionalized cooperation that characterizes human societies" (target article, sect. 7). Hypothesizing that self-interested individuals coercively and collaboratively create rules, we propose that agent-based hypotheses offer viable alternatives to cultural group selection (CGS).

Alternatives to flat panel displays in vehicle turrets

NASA Astrophysics Data System (ADS)

Nicholson, Gail

2011-06-01

Space is a premium in vehicle turrets. Reducing the footprint of displays inside turrets frees up space for the warfighter. Traditional military ruggedized flat panel displays cannot reside flush with the curved turret wall and consumes more space than their advertized size. The lack of turret space also makes balancing human factors difficult. To better meet the Warfighter needs, alternatives and incremental upgrades to the flat panel displays in turrets were compiled. Each alternative technology was assessed against the constraints of a turret. Benefits, issues, and predictions to implementation are summarized. Viable alternatives are being developed into suitable options.

Balancing practicality and hydrologic realism: a parsimonious approach for simulating rapid groundwater recharge via unsaturated-zone preferential flow

USGS Publications Warehouse

Mirus, Benjamin B.; Nimmo, J.R.

2013-01-01

The impact of preferential flow on recharge and contaminant transport poses a considerable challenge to water-resources management. Typical hydrologic models require extensive site characterization, but can underestimate fluxes when preferential flow is significant. A recently developed source-responsive model incorporates film-flow theory with conservation of mass to estimate unsaturated-zone preferential fluxes with readily available data. The term source-responsive describes the sensitivity of preferential flow in response to water availability at the source of input. We present the first rigorous tests of a parsimonious formulation for simulating water table fluctuations using two case studies, both in arid regions with thick unsaturated zones of fractured volcanic rock. Diffuse flow theory cannot adequately capture the observed water table responses at both sites; the source-responsive model is a viable alternative. We treat the active area fraction of preferential flow paths as a scaled function of water inputs at the land surface then calibrate the macropore density to fit observed water table rises. Unlike previous applications, we allow the characteristic film-flow velocity to vary, reflecting the lag time between source and deep water table responses. Analysis of model performance and parameter sensitivity for the two case studies underscores the importance of identifying thresholds for initiation of film flow in unsaturated rocks, and suggests that this parsimonious approach is potentially of great practical value.

CONTECH(R) A-2000 polyvinyl chloride (PVC) plastic pipe.

DOT National Transportation Integrated Search

2015-03-01

Determine the effectiveness and long-term durability of the Contech A-2000 PVC pipe : in an irrigation application. This type of pipe may prove to be a viable alternative to : reinforced concrete pipe (RCP).

Microseed matrix screening for optimization in protein crystallization: what have we learned?

PubMed

D'Arcy, Allan; Bergfors, Terese; Cowan-Jacob, Sandra W; Marsh, May

2014-09-01

Protein crystals obtained in initial screens typically require optimization before they are of X-ray diffraction quality. Seeding is one such optimization method. In classical seeding experiments, the seed crystals are put into new, albeit similar, conditions. The past decade has seen the emergence of an alternative seeding strategy: microseed matrix screening (MMS). In this strategy, the seed crystals are transferred into conditions unrelated to the seed source. Examples of MMS applications from in-house projects and the literature include the generation of multiple crystal forms and different space groups, better diffracting crystals and crystallization of previously uncrystallizable targets. MMS can be implemented robotically, making it a viable option for drug-discovery programs. In conclusion, MMS is a simple, time- and cost-efficient optimization method that is applicable to many recalcitrant crystallization problems.

Microseed matrix screening for optimization in protein crystallization: what have we learned?

PubMed Central

D’Arcy, Allan; Bergfors, Terese; Cowan-Jacob, Sandra W.; Marsh, May

2014-01-01

Protein crystals obtained in initial screens typically require optimization before they are of X-ray diffraction quality. Seeding is one such optimization method. In classical seeding experiments, the seed crystals are put into new, albeit similar, conditions. The past decade has seen the emergence of an alternative seeding strategy: microseed matrix screening (MMS). In this strategy, the seed crystals are transferred into conditions unrelated to the seed source. Examples of MMS applications from in-house projects and the literature include the generation of multiple crystal forms and different space groups, better diffracting crystals and crystallization of previously uncrystallizable targets. MMS can be implemented robotically, making it a viable option for drug-discovery programs. In conclusion, MMS is a simple, time- and cost-efficient optimization method that is applicable to many recalcitrant crystallization problems. PMID:25195878

Using a low melting solvent mixture to extract value from wood biomass

NASA Astrophysics Data System (ADS)

Hiltunen, Jaakko; Kuutti, Lauri; Rovio, Stella; Puhakka, Eini; Virtanen, Tommi; Ohra-Aho, Taina; Vuoti, Sauli

2016-09-01

Green chemistry, sustainability and eco-efficiency are guiding the development of the next generation of industrial chemical processes. The use of non-edible lignocellulosic biomass as a source of chemicals and fuels has recently raised interest due to the need for an alternative to fossil resources. Valorisation mainly focuses on cellulose, which has been used for various industrial scale applications for decades. However, creating an economically more viable value chain would require the exploitation of the other main components, hemicellulose and lignin. Here, we present a new low melting mixture composition based in boric acid and choline chloride, and demonstrate its efficiency in the fractionation of wood-based biomass for the production of non-condensed lignin, suitable for further use in the search for sustainable industrial applications, and for the selective conversion of hemicelluloses into valuable platform chemicals.

Workers' Self-management, Recovered Companies and the Sociology of Work.

PubMed

Ozarow, Daniel; Croucher, Richard

2014-10-01

We analyse how far Argentina's worker-recovered companies (WRCs) have sustained themselves and their principles of equity and workers' self-management since becoming widespread following the country's 2001-2 economic crisis. Specialist Spanish-language sources, survey data and documents are analysed through four key sociological themes. We find that the number of WRCs has increased in Argentina, and that they represent a viable production model. Further, they have generally maintained their central principles and even flourished. This occurred despite the global economic crisis, legal and financial pressures to adopt capitalist practices and management structures, the risk of market absorption and state attempts to coopt, demobilise and depoliticise the movement. We argue that today they function as a much-needed international beacon of an alternative vision for labour and that integration of their experience has potential to revitalise the field.

Wind tunnel tests of the dynamic characteristics of the fluidic rudder

NASA Technical Reports Server (NTRS)

Belsterling, C. A.

1976-01-01

The fourth phase is given of a continuing program to develop the means to stabilize and control aircraft without moving parts or a separate source of power. Previous phases have demonstrated the feasibility of (1) generating adequate control forces on a standard airfoil, (2) controlling those forces with a fluidic amplifier and (3) cascading non-vented fluidic amplifiers operating on ram air supply pressure. The foremost objectives of the fourth phase covered under Part I of this report were to demonstrate a complete force-control system in a wind tunnel environment and to measure its static and dynamic control characteristics. Secondary objectives, covered under Part II, were to evaluate alternate configurations for lift control. The results demonstrate an overall response time of 150 msec, confirming this technology as a viable means for implementing low-cost reliable flight control systems.

Environmental analysis of Lower Pueblo/Lower Los Alamos Canyon, Los Alamos, New Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferenbaugh, R.W.; Buhl, T.E.; Stoker, A.K.

1994-12-01

The radiological survey of the former radioactive waste treatment plant site (TA-45), Acid Canyon, Pueblo Canyon, and Los Alamos Canyon found residual contamination at the site itself and in the channel and banks of Acid, Pueblo, and lower Los Alamos Canyons all the way to the Rio Grande. The largest reservoir of residual radioactivity is in lower Pueblo Canyon, which is on DOE property. However, residual radioactivity does not exceed proposed cleanup criteria in either lower Pueblo or lower Los Alamos Canyons. The three alternatives proposed are (1) to take no action, (2) to construct a sediment trap in lowermore » Pueblo Canyon to prevent further transport of residual radioactivity onto San Ildefonso Indian Pueblo land, and (3) to clean the residual radioactivity from the canyon system. Alternative 2, to cleanup the canyon system, is rejected as a viable alternative. Thousands of truckloads of sediment would have to be removed and disposed of, and this effort is unwarranted by the low levels of contamination present. Residual radioactivity levels, under either present conditions or projected future conditions, will not result in significant radiation doses to persons exposed. Modeling efforts show that future transport activity will not result in any residual radioactivity concentrations higher than those already existing. Thus, although construction of a sediment trap in lower Pueblo Canyon is a viable alternative, this effort also is unwarranted, and the no-action alternative is the preferred alternative.« less

Determination of viable legionellae in engineered water systems: Do we find what we are looking for?

PubMed Central

Kirschner, Alexander K.T.

2016-01-01

In developed countries, legionellae are one of the most important water-based bacterial pathogens caused by management failure of engineered water systems. For routine surveillance of legionellae in engineered water systems and outbreak investigations, cultivation-based standard techniques are currently applied. However, in many cases culture-negative results are obtained despite the presence of viable legionellae, and clinical cases of legionellosis cannot be traced back to their respective contaminated water source. Among the various explanations for these discrepancies, the presence of viable but non-culturable (VBNC) Legionella cells has received increased attention in recent discussions and scientific literature. Alternative culture-independent methods to detect and quantify legionellae have been proposed in order to complement or even substitute the culture method in the future. Such methods should detect VBNC Legionella cells and provide a more comprehensive picture of the presence of legionellae in engineered water systems. However, it is still unclear whether and to what extent these VBNC legionellae are hazardous to human health. Current risk assessment models to predict the risk of legionellosis from Legionella concentrations in the investigated water systems contain many uncertainties and are mainly based on culture-based enumeration. If VBNC legionellae should be considered in future standard analysis, quantitative risk assessment models including VBNC legionellae must be proven to result in better estimates of human health risk than models based on cultivation alone. This review critically evaluates current methods to determine legionellae in the VBNC state, their potential to complement the standard culture-based method in the near future, and summarizes current knowledge on the threat that VBNC legionellae may pose to human health. PMID:26928563

The potential for disinfection of separated faecal matter by urea and by peracetic acid for hygienic nutrient recycling.

PubMed

Vinnerås, B; Holmqvist, A; Bagge, E; Albihn, A; Jönsson, H

2003-09-01

No efficient, reliable, and scale independent disinfection methods for toilet waste are available today for safe recycling of plant nutrients. Therefore, two chemical treatment methods, addition of urea or of PAA (a quaternary mixture of 15% peracetic acid, 15% hydrogen peroxide and 30% acetic acid), were evaluated for disinfection of faecal matter.Degradation of the added urea resulted in 30 g of ammonia nitrogen per kilogram of treated matter and a pH increase to approximately 9.3. This produced an efficient disinfection of E. coli, Enterococcus spp., and Salmonella spp. within 3 weeks (>6log(10) reduction) and a reduction of the chemical resistant Salmonella typhimurium 28b phage, corresponding to a decimal reduction within 7.5 days. No viable Ascaris suum eggs were found after 50 days of treatment. No reduction of spore forming Clostridia spp. was observed. Urea treatment proved to be efficient for disinfection of source separated faecal matter in a scale independent method used for safe recycling of nutrients found in the faecal matter.PAA reduced all of the above indicator organisms within 12 h after application. For this faecal material, with a dry matter content of approximately 10%, an addition of 0.5-1% of PAA (active substance, corresponding to 3.3-6.7% of the Proxitane 15 used) was required before no viable organisms were found in the material. However, this was not tested for the A. suum. No viable spore-forming bacteria or phages were detected. A high rate of bacteria regrowth occurred at 0.15% dosage and 5 days of treatment. PAA is an efficient alternative for disinfection of separated faeces if a rapid treatment is needed.

Determination of viable legionellae in engineered water systems: Do we find what we are looking for?

PubMed

Kirschner, Alexander K T

2016-04-15

In developed countries, legionellae are one of the most important water-based bacterial pathogens caused by management failure of engineered water systems. For routine surveillance of legionellae in engineered water systems and outbreak investigations, cultivation-based standard techniques are currently applied. However, in many cases culture-negative results are obtained despite the presence of viable legionellae, and clinical cases of legionellosis cannot be traced back to their respective contaminated water source. Among the various explanations for these discrepancies, the presence of viable but non-culturable (VBNC) Legionella cells has received increased attention in recent discussions and scientific literature. Alternative culture-independent methods to detect and quantify legionellae have been proposed in order to complement or even substitute the culture method in the future. Such methods should detect VBNC Legionella cells and provide a more comprehensive picture of the presence of legionellae in engineered water systems. However, it is still unclear whether and to what extent these VBNC legionellae are hazardous to human health. Current risk assessment models to predict the risk of legionellosis from Legionella concentrations in the investigated water systems contain many uncertainties and are mainly based on culture-based enumeration. If VBNC legionellae should be considered in future standard analysis, quantitative risk assessment models including VBNC legionellae must be proven to result in better estimates of human health risk than models based on cultivation alone. This review critically evaluates current methods to determine legionellae in the VBNC state, their potential to complement the standard culture-based method in the near future, and summarizes current knowledge on the threat that VBNC legionellae may pose to human health. Copyright © 2016 The Author. Published by Elsevier Ltd.. All rights reserved.

The Role of stocking in the reestablishment and augmentation of native fish in the Lower Colorado River mainstream (1998-2002)

USGS Publications Warehouse

Mueller, Gordon

2003-01-01

Recovery in the main stem will only be accomplished with a dramatic decrease and possibly a total removal of nonnative species. After ten years and over $6 million in expenditures to remove nonnative fish it appears this philosophy is neither technically nor politically viable. In the meantime, stocking is the only alternative available to insure these species don’t disappear. The only viable option appears the creation and maintenance of small, isolated refuge communities where these species have shown they can produce young.

[Dilemmas of health financing].

PubMed

Herrera Zárate, M; González Torres, R

1989-01-01

The economic crisis had had a profound effect on the finances of health services in Mexico. The expenditure on health has decreased, both in absolute terms and in relation to the national gross product. Funding problems have been aggravated by inequities in budget distribution: social security institutions have been favored; geographical distribution of resources is concentrated in the central areas of the country and in the more developed states, and curative health care has prevailed over preventive medicine. Administrative inefficiency hinders even more the appropriate utilization of resources. Diversification of funding sources has been proposed, through external debt, local funding, and specific health taxing. But these proposals are questionable. The high cost of the debt service has reduced international credits as a source of financing. Resource concentration at the federal level, and the different compromises related to the economic solidarity pact have also diminished the potentiality of local state financing. On the other hand, a special health tax is not viable within the current fiscal framework. The alternatives are a better budget planning, a change in the institutional and regional distribution of resources, and improvement in the administrative mechanisms of funding.

Organic materials for printed electronics

NASA Astrophysics Data System (ADS)

Berggren, M.; Nilsson, D.; Robinson, N. D.

2007-01-01

Organic materials can offer a low-cost alternative for printed electronics and flexible displays. However, research in these systems must exploit the differences - via molecular-level control of functionality - compared with inorganic electronics if they are to become commercially viable.

Morristown Alternative Transportation Study Phase II.

DOT National Transportation Integrated Search

2005-10-14

This report summarizes the Phase II planning effort conducted by the park and the US Department of Transportation's Volpe Center (the Volpe Center) to articulate a viable park-community pilot transit service for Morristown National Historical Park. M...

Research notes : faster load rating for steel truss bridges.

DOT National Transportation Integrated Search

2009-03-01

The Oregon Department of Transportation (ODOT) Bridge Engineering Section recently completed a project with Oregon State University to develop a viable, more cost-effective alternative to the manually collected field measurement procedure. The new me...

NOVEL POLYMERIC MEMBRANE FOR DEHYDRATION OF ORGANIC SOLVENTS

EPA Science Inventory

Pervaporation has emerged as an economically viable alternative technology for dehydration of organic solvents, removal of organic compounds and organic/organic separations. Development of a membrane system with suitable flux and selectivity characteristics plays a critical role...

DEHYDRATION OF LOW WATER CONTENT ETHANOL

EPA Science Inventory

Pervaporation has emerged as an economically viable alternative technology for the dehydration of organic solvents, removal of organic compounds from water and organic/organic separations. Development of a membrane system with suitable flux and selectivity characteristics plays a...

Irradiated foods: current trends and technologies

USDA-ARS?s Scientific Manuscript database

Additional demands on keeping food safe and palatable through longer distribution chains have led industry executives to reconsider irradiation and other technologies as viable processing alternatives for many foods. Other intervention technologies (precision thermal, UV, and novel sanitizer formula...

Incorporation of capsaicin in silicone coatings for enhanced antifouling performance

NASA Astrophysics Data System (ADS)

Reddy Jaggari, Karunakar; Zhang Newby, Bi-Min

2002-03-01

Successful use of capsaicin as insect and animal repellant propelled us to use it as a possible antifouling agent. Its non-toxic, non-biocidal, non-leaching properties make it a viable alternative to organotin compounds. In order to optimize the anti-fouling performance of the coating, silicone, the most effective foul-release marine coating, was chosen as the carrier. We have incorporated capsaicin into silicone coating, by both bulk entrapment and surface immobilization. Contact angle measurements on capsaicin-incorporated silicone exhibited an increase in wettability, owing to the presence of capsaicin. FTIR study further confirmed the incorporation of capsaicin in silicone. Bacterial attachment studies were conducted using lake Erie water. While bacteria liberally inhabited the control coating, their presence on the capsaicin-incorporated coating was found to be minimal. These preliminary studies indicate that capsaicin incorporated silicone could be a viable environment friendly alternative to currently used antifouling coatings.

Laboratory Evaluation of Drop-in Solvent Alternatives to n-Propyl Bromide for Vapor Degreasing

NASA Technical Reports Server (NTRS)

Mitchell, Mark A.; Lowrey, Nikki M.

2012-01-01

Based on this limited laboratory study, solvent blends of trans-1,2 dichloroethylene with HFEs, HFCs, or PFCs appear to be viable alternatives to n-propyl bromide for vapor degreasing. The lower boiling points of these blends may lead to greater solvent loss during use. Additional factors must be considered when selecting a solvent substitute, including stability over time, VOC, GWP, toxicity, and business considerations.

Kinetically reduced local Navier-Stokes equations: an alternative approach to hydrodynamics.

PubMed

Karlin, Iliya V; Tomboulides, Ananias G; Frouzakis, Christos E; Ansumali, Santosh

2006-09-01

An alternative approach, the kinetically reduced local Navier-Stokes (KRLNS) equations for the grand potential and the momentum, is proposed for the simulation of low Mach number flows. The Taylor-Green vortex flow is considered in the KRLNS framework, and compared to the results of the direct numerical simulation of the incompressible Navier-Stokes equations. The excellent agreement between the KRLNS equations and the incompressible nonlocal Navier-Stokes equations for this nontrivial time-dependent flow indicates that the former is a viable alternative for computational fluid dynamics at low Mach numbers.

REDUCING CHILDREN'S RISK FROM LEAD IN SOIL

EPA Science Inventory

Traditional methods for reducing risk from elevated levels of soil Pb involves removal, covering, or dilution by mixing with uncontaminated soil. Believing that in situ remediation techniques are viable alternatives, the EPA=s National Risk Management Research Laboratory (NRMRL) ...

Transportation and our aging population : Volpe Center helps shape future policy

DOT National Transportation Integrated Search

1997-01-01

The issue of providing our aging population with viable transportation alternatives to the private automobile is gaining increased attention from policy makers, particularly as members of the baby boom generation approach their retirement years. Howe...

Flexural behavior of R/C beams strengthened with CFRP sheets or fabric

DOT National Transportation Integrated Search

2002-08-01

The resistance to electro-chemical corrosion, high-strength to weight ratio, larger creep strain, fatigue resistance, nonmagnetic and non-metallic properties of carbon fiber reinforced polymer (CFRP) composites offer a viable alternative to bonding o...

Dynamic light scattering: A fast and reliable method to analyze bacterial growth during the lag phase.

PubMed

Vargas, Susana; Millán-Chiu, Blanca E; Arvizu-Medrano, Sofía M; Loske, Achim M; Rodríguez, Rogelio

2017-06-01

A comparison between plate counting (PC) and dynamic light scattering (DLS) is reported. PC is the standard technique to determine bacterial population as a function of time; however, this method has drawbacks, such as the cumbersome preparation and handling of samples, as well as the long time required to obtain results. Alternative methods based on optical density are faster, but do not distinguish viable from non-viable cells. These inconveniences are overcome by using DLS. Two different bacteria strains were considered: Escherichia coli and Staphylococcus aureus. DLS was performed at two different illuminating conditions: continuous and intermittent. By the increment of particle size as a function of time, it was possible to observe cell division and the formation of aggregates containing very few bacteria. The scattered intensity profiles showed the lag phase and the transition to the exponential phase of growth, providing a quantity proportional to viable bacteria concentration. The results revealed a clear and linear correlation in both lag and exponential phase, between the Log 10 (colony-forming units/mL) from PC and the Log 10 of the scattered intensity I s from DLS. These correlations provide a good support to use DLS as an alternative technique to determine bacterial population. Copyright © 2017 Elsevier B.V. All rights reserved.

When will female jaguars cross the border? Socio-demographics of the northern jaguar

Treesearch

Peter Warshall

2013-01-01

Conservation biologists, NGOs, and the USFWS have established a goal of returning a viable population of jaguars into the United States. The source population for this recovery will come from Sonora, Mexico, the closest sub-population of the species. To maintain a viable population there must be females and an active corridor that allows passage of jaguars between...

Wind Energy Program Summary. Volume 2: Research summaries, fiscal year 1988

NASA Astrophysics Data System (ADS)

1989-04-01

Activities by the Federal Wind Energy program since the early 1980s have focused on developing a technology base necessary for industry to demonstrate the viability of wind energy as an alternative energy supply. The Federal Wind Energy Program's research has targeted the sciences of wind turbine dynamics and the development of advanced components and systems. These efforts have resulted in major advancements toward the development and commercialization of wind technology as an alternative energy source. The installation of more than 16,000 wind turbines in California by the end of 1987 provides evidence that commercial use of wind energy technology can be a viable source of electric power. Research in wind turbine sciences has focused on atmospheric fluid dynamics, aerodynamics, and structural dynamics. As outlines in the projects that are described in this document, advancements in atmospheric fluid dynamics have been made through the development and refinement of wind characterization models and wind/rotor interaction prediction codes. Recent gains in aerodynamics can be attributed to a better understanding of airfoil operations, using innovative research approaches such as flow-visualization techniques. Qualitative information and data from laboratory and field tests are being used to document fatigue damage processes. These data are being used to develop new theories and data bases for structural dynamics, and will help to achieve long-term unit life and lower capital and maintenance costs. Material characterization and modeling techniques have been improved to better analyze effects of stress and fatigue on system components.

DVB-S2 Experiment over NASA's Space Network

NASA Technical Reports Server (NTRS)

Downey, Joseph A.; Evans, Michael A.; Tollis, Nicholas S.

2017-01-01

The commercial DVB-S2 standard was successfully demonstrated over NASAs Space Network (SN) and the Tracking Data and Relay Satellite System (TDRSS) during testing conducted September 20-22nd, 2016. This test was a joint effort between NASA Glenn Research Center (GRC) and Goddard Space Flight Center (GSFC) to evaluate the performance of DVB-S2 as an alternative to traditional NASA SN waveforms. Two distinct sets of tests were conducted: one was sourced from the Space Communication and Navigation (SCaN) Testbed, an external payload on the International Space Station, and the other was sourced from GRCs S-band ground station to emulate a Space Network user through TDRSS. In both cases, a commercial off-the-shelf (COTS) receiver made by Newtec was used to receive the signal at White Sands Complex. Using SCaN Testbed, peak data rates of 5.7 Mbps were demonstrated. Peak data rates of 33 Mbps were demonstrated over the GRC S-band ground station through a 10MHz channel over TDRSS, using 32-amplitude phase shift keying (APSK) and a rate 89 low density parity check (LDPC) code. Advanced features of the DVB-S2 standard were evaluated, including variable and adaptive coding and modulation (VCMACM), as well as an adaptive digital pre-distortion (DPD) algorithm. These features provided additional data throughput and increased link performance reliability. This testing has shown that commercial standards are a viable, low-cost alternative for future Space Network users.

Low Intensity Low Temperature (LILT) measurements and coefficients on new photovoltaic structures

NASA Technical Reports Server (NTRS)

Schelman, David A.; Jenkins, Philip P.; Brinker, David J.; Appelbaum, Joseph

1995-01-01

Past NASA missions to Mars, Jupiter, and the outer planets were powered by radioisotope thermal generators (RTG's). Although these devices proved to be reliable, their high cost and highly toxic radioactive heat source has made them far less desirable for future planetary missions. This has resulted in a renewed search for alternate energy sources, some of them being photovoltaic (PV) and thermophotovoltaic (TPV). Both of these alternate energy sources convert light/thermal energy directly into electricity. In order to create a viable PV and TPV data base for planetary mission planners and cell designers, we have compiled low temperature low intensity (LILT) I-V data on single junction and multi-junction high efficiency solar cells. The cells tested here represent the latest photovoltaic technology. Using this LILT data to calculate dI(sub SC)/dT, dV(sub OC)/dT, dFF/dT, and also as a function of intensity, an accurate prediction of cell performance under the AMO spectrum can be determined. When combined with QUantum efficiency at Low Temperature (QULT) data, one can further enhance the data by adding spectral variations to the measurements. This paper presents an overview of LILT measurements and is only intended to be used as a guideline for material selection and performance predictions. As single junction and multi-junction cell technologies emerge, new test data must be collected. Cell materials included are Si, GaAs/Ge, GainP/GaAs/Ge, InP, InGaAs/InP, InP/InGaAs/InP, and GainP. Temperatures range as low as -175 C and intensities range from 1 sun to .02 suns.

Low Intensity Low Temperature (LILT) Measurements and Coefficients on New Photovoltaic Structures

NASA Technical Reports Server (NTRS)

Scheiman, David A.; Jenkins, Phillip P.; Brinker, David J.; Appelbaum, Joseph

1995-01-01

Past NASA missions to Mars, Jupiter and the outer planets were powered by radioisotope thermal generators (RTGs). Although these devices proved to be reliable, their high cost and highly toxic radioactive heat source has made them far less desirable for future planetary missions. This has resulted in a renewed search for alternate energy sources, some of them being photovoltaics (PV) and thermophotovoltaics (TPV). Both of these alternate energy sources convert light/thermal energy directly into electricity. In order to create a viable PV data base for planetary mission planners and cell designers, we have compiled low intensity low temperature (LILT) I-V data on single junction and multi-junction high efficiency solar cells. The cells tested here represent the latest photovoltaic technology. Using this LILT data to calculate Short Circuit Current (I(sub sc)), Open Circuit Voltage (V(sub os)), and Fill Factor (FF) as a function of temperature and intensity, an accurate prediction of cell performance under the AM0 spectrum can be determined. When combined with QUantum efficiency at Low Temperature (QULT) data, one can further enhance the data by adding spectral variations to the measurements. This paper presents an overview of LILT measurements and is only intended to be used as a guideline for material selection and performance predictions. As single junction and multi-junction cell technologies emerge, new test data must be collected. Cell materials included are Si, GaAs/Ge, GaInP/GaAs/GaAs, InP, InGaAs/InP, InP/InGaAs/InP, and GaInP. Temperatures range down to as low as -180 C and intensities range from 1 sun down to 0.02 suns. The coefficients presented in this paper represent experimental results and are intended to provide the user with approximate numbers.

Land use mapping from CBERS-2 images with open source tools by applying different classification algorithms

NASA Astrophysics Data System (ADS)

Sanhouse-García, Antonio J.; Rangel-Peraza, Jesús Gabriel; Bustos-Terrones, Yaneth; García-Ferrer, Alfonso; Mesas-Carrascosa, Francisco J.

2016-02-01

Land cover classification is often based on different characteristics between their classes, but with great homogeneity within each one of them. This cover is obtained through field work or by mean of processing satellite images. Field work involves high costs; therefore, digital image processing techniques have become an important alternative to perform this task. However, in some developing countries and particularly in Casacoima municipality in Venezuela, there is a lack of geographic information systems due to the lack of updated information and high costs in software license acquisition. This research proposes a low cost methodology to develop thematic mapping of local land use and types of coverage in areas with scarce resources. Thematic mapping was developed from CBERS-2 images and spatial information available on the network using open source tools. The supervised classification method per pixel and per region was applied using different classification algorithms and comparing them among themselves. Classification method per pixel was based on Maxver algorithms (maximum likelihood) and Euclidean distance (minimum distance), while per region classification was based on the Bhattacharya algorithm. Satisfactory results were obtained from per region classification, where overall reliability of 83.93% and kappa index of 0.81% were observed. Maxver algorithm showed a reliability value of 73.36% and kappa index 0.69%, while Euclidean distance obtained values of 67.17% and 0.61% for reliability and kappa index, respectively. It was demonstrated that the proposed methodology was very useful in cartographic processing and updating, which in turn serve as a support to develop management plans and land management. Hence, open source tools showed to be an economically viable alternative not only for forestry organizations, but for the general public, allowing them to develop projects in economically depressed and/or environmentally threatened areas.

Is biological treatment a viable alternative for micropollutant removal in drinking water treatment processes?

PubMed

Benner, Jessica; Helbling, Damian E; Kohler, Hans-Peter E; Wittebol, Janneke; Kaiser, Elena; Prasse, Carsten; Ternes, Thomas A; Albers, Christian N; Aamand, Jens; Horemans, Benjamin; Springael, Dirk; Walravens, Eddy; Boon, Nico

2013-10-15

In western societies, clean and safe drinking water is often taken for granted, but there are threats to drinking water resources that should not be underestimated. Contamination of drinking water sources by anthropogenic chemicals is one threat that is particularly widespread in industrialized nations. Recently, a significant amount of attention has been given to the occurrence of micropollutants in the urban water cycle. Micropollutants are bioactive and/or persistent chemicals originating from diverse sources that are frequently detected in water resources in the pg/L to μg/L range. The aim of this review is to critically evaluate the viability of biological treatment processes as a means to remove micropollutants from drinking water resources. We first place the micropollutant problem in context by providing a comprehensive summary of the reported occurrence of micropollutants in raw water used directly for drinking water production and in finished drinking water. We then present a critical discussion on conventional and advanced drinking water treatment processes and their contribution to micropollutant removal. Finally, we propose biological treatment and bioaugmentation as a potential targeted, cost-effective, and sustainable alternative to existing processes while critically examining the technical limitations and scientific challenges that need to be addressed prior to implementation. This review will serve as a valuable source of data and literature for water utilities, water researchers, policy makers, and environmental consultants. Meanwhile this review will open the door to meaningful discussion on the feasibility and application of biological treatment and bioaugmentation in drinking water treatment processes to protect the public from exposure to micropollutants. Copyright © 2013 Elsevier Ltd. All rights reserved.

Controlled soil warming powered by alternative energy for remote field sites.

PubMed

Johnstone, Jill F; Henkelman, Jonathan; Allen, Kirsten; Helgason, Warren; Bedard-Haughn, Angela

2013-01-01

Experiments using controlled manipulation of climate variables in the field are critical for developing and testing mechanistic models of ecosystem responses to climate change. Despite rapid changes in climate observed in many high latitude and high altitude environments, controlled manipulations in these remote regions have largely been limited to passive experimental methods with variable effects on environmental factors. In this study, we tested a method of controlled soil warming suitable for remote field locations that can be powered using alternative energy sources. The design was tested in high latitude, alpine tundra of southern Yukon Territory, Canada, in 2010 and 2011. Electrical warming probes were inserted vertically in the near-surface soil and powered with photovoltaics attached to a monitoring and control system. The warming manipulation achieved a stable target warming of 1.3 to 2 °C in 1 m(2) plots while minimizing disturbance to soil and vegetation. Active control of power output in the warming plots allowed the treatment to closely match spatial and temporal variations in soil temperature while optimizing system performance during periods of low power supply. Active soil heating with vertical electric probes powered by alternative energy is a viable option for remote sites and presents a low-disturbance option for soil warming experiments. This active heating design provides a valuable tool for examining the impacts of soil warming on ecosystem processes.

Economic feasibility of the sugar beet-to-ethylene value chain.

PubMed

Althoff, Jeroen; Biesheuvel, Kees; De Kok, Ad; Pelt, Henk; Ruitenbeek, Matthijs; Spork, Ger; Tange, Jan; Wevers, Ronald

2013-09-01

As part of a long-term strategy toward renewable feedstock, a feasibility study into options for the production of bioethylene by integrating the sugar beet-to-ethanol-to-ethylene value chain. Seven business cases were studied and tested for actual economic feasibility of alternative sugar-to-ethanol-to-ethylene routes in comparison to fossil-fuel alternatives. An elaborate model was developed to assess the relevant operational and financial aspects of each business case. The calculations indicate that bioethylene from sugar beet is not commercially viable under current market conditions. In light of expected global energy and feedstock prices it is also reasonable to expect that this will not change in the near future. To consider biorenewable sources as starting material, they need to be low in cost (compared to sugar beets) and also require less capital and energy-intensive methods for the conversion to chemicals. In general, European sugar prices will be too high for many chemical applications. Future efforts for in sugar-to-chemicals routes should, therefore, focus on integrated process routes and process intensification and/or on products that contain a significant part of the original carbohydrate backbone. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Strategies for Lipid Production Improvement in Microalgae as a Biodiesel Feedstock

PubMed Central

Li, Z. H.; Hiltunen, E.

2016-01-01

In response to the energy crisis, global warming, and climate changes, microalgae have received a great deal of attention as a biofuel feedstock. Due to a high lipid content in microalgal cells, microalgae present as a promising alternative source for the production of biodiesel. Environmental and culturing condition variations can alter lipid production as well as chemical compositions of microalgae. Therefore, application of the strategies to activate lipid accumulation opens the door for lipid overproduction in microalgae. Until now, many original studies regarding the approaches for enhanced microalgal lipid production have been reported in an effort to push forward the production of microalgal biodiesel. However, the current literature demonstrates fragmented information available regarding the strategies for lipid production improvement. From the systematic point of view, the review highlights the main approaches for microalgal lipid accumulation induction to expedite the application of microalgal biodiesel as an alternative to fossil diesel for sustainable environment. Of the several strategies discussed, the one that is most commonly applied is the design of nutrient (e.g., nitrogen, phosphorus, and sulfur) starvation or limitation. Other viable approaches such as light intensity, temperature, carbon dioxide, salinity stress, and metal influence can also achieve enhanced microalgal lipid production. PMID:27725942

Strategies for Lipid Production Improvement in Microalgae as a Biodiesel Feedstock.

PubMed

Zhu, L D; Li, Z H; Hiltunen, E

2016-01-01

In response to the energy crisis, global warming, and climate changes, microalgae have received a great deal of attention as a biofuel feedstock. Due to a high lipid content in microalgal cells, microalgae present as a promising alternative source for the production of biodiesel. Environmental and culturing condition variations can alter lipid production as well as chemical compositions of microalgae. Therefore, application of the strategies to activate lipid accumulation opens the door for lipid overproduction in microalgae. Until now, many original studies regarding the approaches for enhanced microalgal lipid production have been reported in an effort to push forward the production of microalgal biodiesel. However, the current literature demonstrates fragmented information available regarding the strategies for lipid production improvement. From the systematic point of view, the review highlights the main approaches for microalgal lipid accumulation induction to expedite the application of microalgal biodiesel as an alternative to fossil diesel for sustainable environment. Of the several strategies discussed, the one that is most commonly applied is the design of nutrient (e.g., nitrogen, phosphorus, and sulfur) starvation or limitation. Other viable approaches such as light intensity, temperature, carbon dioxide, salinity stress, and metal influence can also achieve enhanced microalgal lipid production.

Attitudes of Nigerian physicians toward a National Health Service.

PubMed

Umeh, J C; Freeman, R A; Garner, D D; Blevins, D E

1986-01-01

Despite efforts to improve health services in Nigeria, considerable problems in distribution and access persist. At present, the health care system in Nigeria is organized and financed at the states' level rather than at the national level. A severe maldistribution of resources exists, as does a lack of coordination among states. An alternative system, albeit expensive, is a National Health Service (NHS). The purpose of this research is to quantify physicians' attitudes towards the concept of NHS. Although physicians in Nigeria are mandated to provide government-funded support, a substantial private practice thrives. Accordingly, physicians' attitudes that may be transferred into behavior are a major determinate of a potential NHS' long term success. In summary, Hausa physicians from the north tended to be more favorable to NHS than did others. Also, younger physicians and those who believed Nigeria's present system to be inadequate favored NHS. There was no association between a physician's gender, locus of medical education, and source of support for medication education and attitude. Finally, physicians in private practice and those in urban areas held more negative attitudes. In spite of Nigeria's present difficulties, a NHS may become a viable alternative. At this point, the overall concept is not opposed by physicians.

Options for Kentucky's Energy Future

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larry Demick

2012-11-01

Three important imperatives are being pursued by the Commonwealth of Kentucky: ? Developing a viable economic future for the highly trained and experienced workforce and for the Paducah area that today supports, and is supported by, the operations of the US Department of Energy’s (DOE’s) Paducah Gaseous Diffusion Plant (PGDP). Currently, the PGDP is scheduled to be taken out of service in May, 2013. ? Restructuring the economic future for Kentucky’s most abundant indigenous resource and an important industry – the extraction and utilization of coal. The future of coal is being challenged by evolving and increasing requirements for itsmore » extraction and use, primarily from the perspective of environmental restrictions. Further, it is important that the economic value derived from this important resource for the Commonwealth, its people and its economy is commensurate with the risks involved. Over 70% of the extracted coal is exported from the Commonwealth and hence not used to directly expand the Commonwealth’s economy beyond the severance taxes on coal production. ? Ensuring a viable energy future for Kentucky to guarantee a continued reliable and affordable source of energy for its industries and people. Today, over 90% of Kentucky’s electricity is generated by burning coal with a delivered electric power price that is among the lowest in the United States. Anticipated increased environmental requirements necessitate looking at alternative forms of energy production, and in particular electricity generation.« less

7 CFR 622.2 - Scope.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS General § 622.2 Scope. (a) To assist sponsors in preparing and carrying out watershed plans, the Natural Resources Conservation Service (NRCS) shall conduct... extent of watershed problems and needs, and (2) Set forth viable alternative solutions consistent with...

7 CFR 622.2 - Scope.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS General § 622.2 Scope. (a) To assist sponsors in preparing and carrying out watershed plans, the Natural Resources Conservation Service (NRCS) shall conduct... extent of watershed problems and needs, and (2) Set forth viable alternative solutions consistent with...

7 CFR 622.2 - Scope.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS General § 622.2 Scope. (a) To assist sponsors in preparing and carrying out watershed plans, the Natural Resources Conservation Service (NRCS) shall conduct... extent of watershed problems and needs, and (2) Set forth viable alternative solutions consistent with...

7 CFR 622.2 - Scope.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS General § 622.2 Scope. (a) To assist sponsors in preparing and carrying out watershed plans, the Natural Resources Conservation Service (NRCS) shall conduct... extent of watershed problems and needs, and (2) Set forth viable alternative solutions consistent with...

Microwave Pretreatment For Hydrolysis Of Cellulose

NASA Technical Reports Server (NTRS)

Cullingford, Hatice S.; George, Clifford E.; Lightsey, George R.

1993-01-01

Microwave pretreatment enhances enzymatic hydrolysis of cellulosic wastes into soluble saccharides used as feedstocks for foods, fuels, and other products. Low consumption of energy, high yield, and low risk of proposed hydrolysis process incorporating microwave pretreatment makes process viable alternative to composting.

Evaluation of the economic viability of narrow-gauge local rail systems

DOT National Transportation Integrated Search

2001-11-01

The purpose of this project is to investigate and determine whether narrow-gauge local rail is a viable transportation alternative in Florida. A number of proposals for transit greenways have been developed for various communities throughout Florida....

Near-infrared counterparts to the Galactic Bulge Survey X-ray source population

NASA Astrophysics Data System (ADS)

Greiss, S.; Steeghs, D.; Jonker, P. G.; Torres, M. A. P.; Maccarone, T. J.; Hynes, R. I.; Britt, C. T.; Nelemans, G.; Gänsicke, B. T.

2014-03-01

We report on the near-infrared matches, drawn from three surveys, to the 1640 unique X-ray sources detected by Chandra in the Galactic Bulge Survey (GBS). This survey targets faint X-ray sources in the bulge, with a particular focus on accreting compact objects. We present all viable counterpart candidates and associate a false alarm probability (FAP) to each near-infrared match in order to identify the most likely counterparts. The FAP takes into account a statistical study involving a chance alignment test, as well as considering the positional accuracy of the individual X-ray sources. We find that although the star density in the bulge is very high, ˜90 per cent of our sources have an FAP <10 per cent, indicating that for most X-ray sources, viable near-infrared counterparts candidates can be identified. In addition to the FAP, we provide positional and photometric information for candidate counterparts to ˜95 per cent of the GBS X-ray sources. This information in combination with optical photometry, spectroscopy and variability constraints will be crucial to characterize and classify secure counterparts.

Remediating Contaminant Plumes in Groundwater with Shallow Excavations Containing Coarse Reactive Media.

PubMed

Hudak, Paul F

2018-02-01

A groundwater flow and mass transport model tested the capability of shallow excavations filled with coarse, reactive media to remediate a hypothetical unconfined aquifer with a maximum saturated thickness of 5 m. Modeled as contaminant sinks, the rectangular excavations were 10 m downgradient of an initial contaminant plume originating from a source at the top of the aquifer. The initial plume was approximately 259 m long, 23 m wide, and 5 m thick, with a downgradient tip located approximately 100 m upgradient of the site boundary. The smallest trench capable of preventing offsite migration was 11 m long (measured perpendicular to groundwater flow), 4 m wide (measured parallel to groundwater flow), and 3 m deep. Results of this study suggest that shallow trenches filled with coarse filter media that partially penetrate unconfined aquifers may be a viable alternative for remediating contaminated groundwater at some sites.

Towards the use of OCT angiography in clinical dermatology

NASA Astrophysics Data System (ADS)

Baran, Utku; Choi, Woo June; Wang, Ruikang K.

2016-02-01

Optical coherence tomography (OCT) is a popular imaging technique used in ophthalmology, and on the way to become clinically viable alternative in dermatology due to its capability of acquiring histopathology level images of in vivo tissue, noninvasively. In this study, we demonstrate the capabilities of OCT-based angiography (OMAG) in detecting high-resolution, volumetric structural and microvascular features of in vivo human skin with various conditions using a swept source OCT system that operates on a central wavelength of 1310 nm with an A-line rate of 100 kHz. OMAG images provide detailed in vivo visualization of microvasculature of abnormal human skin conditions from face, chest and belly. Moreover, the progress of wound healing on human skin from arm is monitored during longitudinal wound healing process. The presented results promise the clinical use of OCT angiography in treatment of prevalent cutaneous diseases within human skin, in vivo.

Current and New Insights in the Sustainable and Green Recovery of Nutritionally Valuable Compounds from Stevia rebaudiana Bertoni.

PubMed

Koubaa, Mohamed; Roselló-Soto, Elena; Šic Žlabur, Jana; Režek Jambrak, Anet; Brnčić, Mladen; Grimi, Nabil; Boussetta, Nadia; Barba, Francisco J

2015-08-12

The South American plant Stevia rebaudiana Bertoni is a great source of noncaloric sweeteners (steviol glycosides), mainly concentrated in its leaves, but also has important antioxidant compounds (vitamin C, polyphenols, chlorophylls, and carotenoids) and other important macro- and micronutrients such as folic acid and all of the essential amino acids except tryptophan. Traditionally, conventional methods have been used to recover nutritionally valuable compounds from plant food matrices. However, nowadays, the need for obtaining greener, sustainable, and viable processes has led both food industries and food scientists to develop new processes in full correspondence with the green extraction concept. This review focuses on some of the most promising nonconventional and emerging technologies, which may constitute a potential alternative to conventional methods or even could be combined to obtain a synergistic effect, thus reducing extraction time as well as solvent consumption and avoiding the use of toxic solvents.

Automatic vision-based grain optimization and analysis of multi-crystalline solar wafers using hierarchical region growing

NASA Astrophysics Data System (ADS)

Fan, Shu-Kai S.; Tsai, Du-Ming; Chuang, Wei-Che

2017-04-01

Solar power has become an attractive alternative source of energy. The multi-crystalline solar cell has been widely accepted in the market because it has a relatively low manufacturing cost. Multi-crystalline solar wafers with larger grain sizes and fewer grain boundaries are higher quality and convert energy more efficiently than mono-crystalline solar cells. In this article, a new image processing method is proposed for assessing the wafer quality. An adaptive segmentation algorithm based on region growing is developed to separate the closed regions of individual grains. Using the proposed method, the shape and size of each grain in the wafer image can be precisely evaluated. Two measures of average grain size are taken from the literature and modified to estimate the average grain size. The resulting average grain size estimate dictates the quality of the crystalline solar wafers and can be considered a viable quantitative indicator of conversion efficiency.

Biomaterials in myocardial tissue engineering

PubMed Central

Reis, Lewis A.; Chiu, Loraine L. Y.; Feric, Nicole; Fu, Lara; Radisic, Milica

2016-01-01

Cardiovascular disease is the leading cause of death in the developed world, and as such there is a pressing need for treatment options. Cardiac tissue engineering emerged from the need to develop alternate sources and methods of replacing tissue damaged by cardiovascular diseases, as the ultimate treatment option for many who suffer from end-stage heart failure is a heart transplant. In this review we focus on biomaterial approaches to augment injured or impaired myocardium with specific emphasis on: the design criteria for these biomaterials; the types of scaffolds—composed of natural or synthetic biomaterials, or decellularized extracellular matrix—that have been used to develop cardiac patches and tissue models; methods to vascularize scaffolds and engineered tissue, and finally injectable biomaterials (hydrogels)designed for endogenous repair, exogenous repair or as bulking agents to maintain ventricular geometry post-infarct. The challenges facing the field and obstacles that must be overcome to develop truly clinically viable cardiac therapies are also discussed. PMID:25066525

Clinical skill development for community pharmacists.

PubMed

Barnette, D J; Murphy, C M; Carter, B L

1996-09-01

The importance of establishing clinical pharmacy services in the community cannot be understated in light of current challenges to the traditional dispensing role as the primary service of the community pharmacist. Advancements in automated dispensing technology and declining prescription fee reimbursement are rapidly forcing pharmacists to seek alternative sources of revenue. Providing pharmaceutical care is a viable option to increase customer loyalty job satisfaction, and reimbursement. To support the development of clinical services, academic institutions are forming partnerships with individual community practitioners to overcome perceived educational and training barriers. The authors describe the design and development of two unique clinical skill development programs at the University of Illinois at Chicago. This paper also outlines the patient focused services that the participants have established upon completing the training. These programs successfully enhanced participants' therapeutic knowledge base and facilitated development of the clinical skills necessary for direct patient care.

Chemical and physical aspects of refining coal liquids

NASA Astrophysics Data System (ADS)

Shah, Y. T.; Stiegel, G. J.; Krishnamurthy, S.

1981-02-01

Increasing costs and declining reserves of petroleum are forcing oil importing countries to develop alternate energy sources. The direct liquefaction of coal is currently being investigated as a viable means of producing substitute liquid fuels. The coal liquids derived from such processes are typically high in nitrogen, oxygen and sulfur besides having a high aromatic and metals content. It is therefore envisaged that modifications to existing petroleum refining technology will be necessary in order to economically upgrade coal liquids. In this review, compositional data for various coal liquids are presented and compared with those for petroleum fuels. Studies reported on the stability of coal liquids are discussed. The feasibility of processing blends of coal liquids with petroleum feedstocks in existing refineries is evaluated. The chemistry of hydroprocessing is discussed through kinetic and mechanistic studies using compounds which are commonly detected in coal liquids. The pros and cons of using conventional petroleum refining catalysts for upgrading coal liquids are discussed.

Utilization of physician health care services in Mexico by U.S. Hispanic border residents.

PubMed

Landeck, Michael; Garza, Cecilia

2002-01-01

One of the most controversial topics in the U.S. is the issue of accessibility to health services by U.S. residents. This issue is most critical to U.S. Hispanic residents living along the U.S.-Mexico border who have been identified as having low health standards and low socio-economic conditions when compared to the rest of the state and the country. The availability of lower cost health services across the U.S. border in Mexico is, therefore, perceived as a viable economic alternative source of health care. This study is derived from a health needs assessment survey of 1,100 households residing in Laredo, Texas, the largest land port along the 2,000-miles long U.S.-Mexico border. The major result of this study indicates that about 41.2 percent of the Laredo U.S. Hispanic residents are utilizing cross border physician health care services in Mexico.

Workers’ Self-management, Recovered Companies and the Sociology of Work

PubMed Central

Croucher, Richard

2014-01-01

We analyse how far Argentina’s worker-recovered companies (WRCs) have sustained themselves and their principles of equity and workers’ self-management since becoming widespread following the country’s 2001–2 economic crisis. Specialist Spanish-language sources, survey data and documents are analysed through four key sociological themes. We find that the number of WRCs has increased in Argentina, and that they represent a viable production model. Further, they have generally maintained their central principles and even flourished. This occurred despite the global economic crisis, legal and financial pressures to adopt capitalist practices and management structures, the risk of market absorption and state attempts to coopt, demobilise and depoliticise the movement. We argue that today they function as a much-needed international beacon of an alternative vision for labour and that integration of their experience has potential to revitalise the field. PMID:25419009

Tin-Doped Inorganic Amorphous Films for Use as Transparent Monolithic Phosphors.

PubMed

Masai, Hirokazu; Miyata, Hiroki; Yamada, Yasuhiro; Okumura, Shun; Yanagida, Takayuki; Kanemitsu, Yoshihiko

2015-06-10

Although inorganic crystalline phosphors can exhibit high quantum efficiency, their use in phosphor films has been limited by a reliance on organic binders that have poor durability when exposed to high-power and/or high excitation energy light sources. To address this problem, Sn(2+)-doped transparent phosphate films measuring several micrometers in thickness have been successfully prepared through heat treatment and a subsequent single dip-coating process. The resulting monolithic inorganic amorphous film exhibited an internal quantum efficiency of over 60% and can potentially utilize transmitted light. Analysis of the film's emissivity revealed that its color can be tuned by changing the amount of Mn and Sn added to influence the energy transfer from Sn(2+) to Mn(2+). It is therefore concluded that amorphous films containing such emission centers can provide a novel and viable alternative to conventional amorphous films containing crystalline phosphors in light-emitting devices.

The effect of prior education on students' competency in digital logic: the case of ultraorthodox Jewish students

NASA Astrophysics Data System (ADS)

Ben-David Kolikant, Yifat; Genut, Sara

2017-10-01

In line with the growing interest in extending the diversity of CS students, we examined the performance of a unique group of students studying an introductory course in Digital logic: ultraorthodox Jewish men, whose previous education was based mostly on studying Talmud and who lacked a conventional high-school education. We used questions from the Digital Logic Concept Inventory . We compared the results to those of religious Jewish men with a conventional high-school education, and to the results reported in the literature. The ultraorthodox group performed better than the other groups in tasks that concerned number representation. No other statistically significant differences were found. Talk-aloud protocols revealed that the ultraorthodox students utilized a viable conceptual understanding in their performance. We can conclude that students' unique, alternative prior education should not be merely viewed as an obstacle to their academic studies, but also as a potential source for strengths.

Nano-Filament Field Emission Cathode Development Final Report CRADA No. TSB-0731-93

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bernhardt, Tony; Fahlen, Ted

At the time the CRADA was established, Silicon Video Corporation, of Cupertino, CA was a one-year-old rapidly growing start-up company. SVC was developing flat panel displays (FPDs) to replace Cathode Ray Terminals (CRTs) for personal computers, work stations and televisions. They planned to base their products on low cost and energy efficient field emission technology. It was universally recognized that the display was both the dominant cost item and differentiating feature of many products such as laptop computers and hand-held electronics and that control of the display technology through U.S. sources was essential to success in these markets. The purposemore » of this CRADA project was to determine if electrochemical planarization would be a viable, inexpensive alternative to current optical polishing techniques for planarizing the surface of a ceramic backplate of a thin film display.« less

Tin-Doped Inorganic Amorphous Films for Use as Transparent Monolithic Phosphors

PubMed Central

Masai, Hirokazu; Miyata, Hiroki; Yamada, Yasuhiro; Okumura, Shun; Yanagida, Takayuki; Kanemitsu, Yoshihiko

2015-01-01

Although inorganic crystalline phosphors can exhibit high quantum efficiency, their use in phosphor films has been limited by a reliance on organic binders that have poor durability when exposed to high-power and/or high excitation energy light sources. To address this problem, Sn2+ -doped transparent phosphate films measuring several micrometers in thickness have been successfully prepared through heat treatment and a subsequent single dip-coating process. The resulting monolithic inorganic amorphous film exhibited an internal quantum efficiency of over 60% and can potentially utilize transmitted light. Analysis of the film’s emissivity revealed that its color can be tuned by changing the amount of Mn and Sn added to influence the energy transfer from Sn2+ to Mn2+. It is therefore concluded that amorphous films containing such emission centers can provide a novel and viable alternative to conventional amorphous films containing crystalline phosphors in light-emitting devices. PMID:26061744

Mycoplasma testing of cell substrates and biologics: Review of alternative non-microbiological techniques.

PubMed

Volokhov, Dmitriy V; Graham, Laurie J; Brorson, Kurt A; Chizhikov, Vladimir E

2011-01-01

Mycoplasmas, particularly species of the genera Mycoplasma and Acholeplasma, are known to be occasional microbial contaminants of cell cultures that produce biologics. This presents a serious concern regarding the risk of mycoplasma contamination for research laboratories and commercial facilities developing and manufacturing cell-derived biological and biopharmaceutical products for therapeutic use. Potential undetected contamination of these products or process intermediates with mycoplasmas represents a potential safety risk for patients and a business risk for producers of biopharmaceuticals. To minimize these risks, monitoring for adventitious agents, such as viruses and mycoplasmas, is performed during the manufacture of biologics produced in cell culture substrates. The "gold standard" microbiological assay, currently recommended by the USP, EP, JP and the US FDA, for the mycoplasma testing of biologics, involves the culture of viable mycoplasmas in broth, agar plates and indicator cells. Although the procedure enables highly efficient mycoplasma detection in cell substrates and cell-derived products, the overall testing strategy is time consuming (a minimum of 28 days) and requires skilled interpretation of the results. The long time period required for these conventional assays does not permit their use for products with short shelf-lives or for timely 'go/no-go' decisions during routine in-process testing. PCR methodology has existed for decades, however PCR based and other alternative methods for mycoplasma detection have only recently been considered for application to biologics manufacture. The application of alternative nucleic acid-based, enzyme-based and/or recombinant cell-culture methods, particularly in combination with efficient sample preparation procedures, could provide advantages over conventional microbiological methods in terms of analytical throughput, simplicity, and turnaround time. However, a challenge to the application of alternative methods for detection of mycoplasmas remains whether these alternative methods can provide a limit of detection comparable or superior to those of the culture methods. An additional challenge is that nucleic acid amplification technique (NAT) methods do not allow for accurate discrimination between viable and non-viable mycoplasma contaminants, which might lead to false-positive results (e.g. from inactivated raw materials, etc.). Our review provides an overview of these alternative methods and discusses the pros and cons of their application for the testing of mycoplasmas in biologics and cell substrates. Published by Elsevier Ltd.

The point system for driver license administration : a viable alternative for Virginia?.

DOT National Transportation Integrated Search

1972-01-01

Traffic safety research was noted to have been unable to produce any empirical evidence that the introduction of a point system would affect, either negatively or positively, traffic accident statistics. In view of this absence of evidence, the simil...

Evaluation of Oregon's first hot mix asphalt recycling project : Woodburn, Oregon, 1977.

DOT National Transportation Integrated Search

1979-03-01

Pavement recycling has been suggested as a viable alternative to more conventional methods of pavement rehabilitation as a means of offsetting some of the problems resulting from spiraling energy costs and shortages of raw materials. This paper prese...

CEC Today, 2000-2001.

ERIC Educational Resources Information Center

Van Kuren, Lynda, Ed.

2001-01-01

Nine issues of the newsletter of the Council for Exceptional Children (CEC) include articles, news items, meeting announcements, news items of individual divisions, and professional advancement opportunities. Some major articles are: (1) "Home Schooling--A Viable Alternative for Students with Special Needs" (2) "High Stakes Testing…

DEHYDRATION OF ALCOHOLS VIA PREVAPORATION USING A NOVEL HYDROPHILIC MEMBRANE

EPA Science Inventory

Pervaporation has emerged as an economically viable alternative technology for the dehydration of organic solvents, removal of organic compounds from water and organic/organic separations. Development of a suitable membrane system with high flux and high selectivity plays a criti...

Microsilica modified concrete for bridge deck overlays : construction report.

DOT National Transportation Integrated Search

1990-10-01

The study objective was to see if microsilica concrete (MC) is a viable alternative to the latex modified concrete (LMC) usually used on bridge deck overlays in Oregon. The study addresses MC overlays placed in 1989 on Portland cement concrete (PCC) ...

Wireless GPS fleet tracking system at the University of Albany.

DOT National Transportation Integrated Search

2014-07-01

This report provides an overview of the project undertaken at the University at Albany to make alternative transportation a more : viable option by implementing a GPS Tracking System on the University bus fleet and broadcasting the bus locations to c...

9 CFR 381.150 - Requirements for the production of fully cooked poultry products and partially cooked poultry...

Code of Federal Regulations, 2011 CFR

2011-01-01

... standards: (1) Lethality. A 7-log10 reduction of Salmonella or an alternative lethality that achieves an equivalent probability that no viable Salmonella organisms remain in the finished product, as well as the...

DEHYDRATION OF ALCOHOLS VIA PERVAPORATION USING A NOVEL HYDROHILIC MEMBRANE

EPA Science Inventory

Pervaporation has emerged as an economically viable alternative technology for the dehydration of organic solvents, removal of organic compounds from water and organic/organic separations. Development of a suitable membrane system with high flux and high selectivity plays a criti...

High Performance Thin Layer Chromatography.

ERIC Educational Resources Information Center

Costanzo, Samuel J.

1984-01-01

Clarifies where in the scheme of modern chromatography high performance thin layer chromatography (TLC) fits and why in some situations it is a viable alternative to gas and high performance liquid chromatography. New TLC plates, sample applications, plate development, and instrumental techniques are considered. (JN)

Alternatives for NASTRAN maintenance, modification and dissemination

NASA Technical Reports Server (NTRS)

Schaeffer, H. G.

1977-01-01

Various alternatives to direct NASA support of the program are considered ranging from no support at one end of the spectrum to subsidizing a non profit user's group at the other. Of all the alternatives that are developed, the user group appears to be most viable. NASA's past and future roles in the development of computerized technology are also considered. The need for an institute for computational analysis is identified and NASA's possible involvement is described. The goals of the proposed institute and research funds to support an activity that has the potential of a much larger impact on the technical community are identified.

Kinetic Resolution of Secondary Alcohols Using Amidine-Based Catalysts

PubMed Central

Li, Ximin; Jiang, Hui; Uffman, Eric W.; Guo, Lei; Zhang, Yuhua; Yang, Xing; Birman, Vladimir B.

2012-01-01

Kinetic resolution of racemic alcohols has been traditionally achieved via enzymatic enantioselective esterification and ester hydrolysis. However, there has long been considerable interest in devising nonenzymatic alternative methods for this transformation. Amidine-Based Catalysts (ABCs), a new class of enantioselective acyl transfer catalysts developed in our group, have demonstrated, inter alia, high efficacy in the kinetic resolution of benzylic, allylic and propargylic secondary alcohols and 2-substituted cycloalkanols, and thus provide a viable alternative to enzymes. PMID:22283696

An Analysis of AAFES and Its Relevance to the Future of the Army and Air Force

DTIC Science & Technology

2009-06-12

benefits of this organization and are there any viable alternatives? Background and Significance AAFES provides retail goods and services to a select...relative to cost, benefit , and alternative options. Assumptions This study is based on the assumptions that AAFES and the MWR programs of the Army...AAFES is a joint Army and Air Force non-appropriated fund instrumentality (NAFI) charged with operating retail and service activities for the benefit

How Close We Are to Achieving Commercially Viable Large-Scale Photobiological Hydrogen Production by Cyanobacteria: A Review of the Biological Aspects

PubMed Central

Sakurai, Hidehiro; Masukawa, Hajime; Kitashima, Masaharu; Inoue, Kazuhito

2015-01-01

Photobiological production of H2 by cyanobacteria is considered to be an ideal source of renewable energy because the inputs, water and sunlight, are abundant. The products of photobiological systems are H2 and O2; the H2 can be used as the energy source of fuel cells, etc., which generate electricity at high efficiencies and minimal pollution, as the waste product is H2O. Overall, production of commercially viable algal fuels in any form, including biomass and biodiesel, is challenging, and the very few systems that are operational have yet to be evaluated. In this paper we will: briefly review some of the necessary conditions for economical production, summarize the reports of photobiological H2 production by cyanobacteria, present our schemes for future production, and discuss the necessity for further progress in the research needed to achieve commercially viable large-scale H2 production. PMID:25793279

CQI proiect Every other day nocturnal HHD - An alternative approach to reduce burden.

PubMed

2016-08-01

More frequent dialysis, typically performed five to six times per week at home, has been associated with a num- ber of clinical, cardiovascular, and health-related quality of life (HRQOL) benefits. Daily therapy often results in a burden for patients and care partners. A continuous qual- ity improvement (CQI) initiative was conducted to evaluate if an alternate day, longer duration therapy (3.5 treatments with six to 10 hour treatments per week) would provide a viable alternative for home hemodialysis (HHD). This initia- tive demonstrated that every other day (EOD) nocturnal HD is a feasible alternative option to daily HHD and should be considered to individualize home dialysis therapy.

Viability, diversity and composition of the bacterial community in a high Arctic permafrost soil from Spitsbergen, Northern Norway.

PubMed

Hansen, Aviaja A; Herbert, Rodney A; Mikkelsen, Karina; Jensen, Lars Liengård; Kristoffersen, Tommy; Tiedje, James M; Lomstein, Bente Aa; Finster, Kai W

2007-11-01

The viable and non-viable fractions of the bacterial community in a 2347-year-old permafrost soil from Spitsbergen were subjected to a comprehensive investigation using culture-independent and culture-dependent methods. LIVE/DEAD BacLight staining revealed that 26% of the total number of bacterial cells were viable. Quantitatively, aerobic microcolonies, aerobic colony-forming units and culturable anaerobic bacteria comprised a minor fraction of the total number of viable bacteria, which underlines the necessity for alternative cultivation approaches in bacterial cryobiology. Sulfate reduction was detected at temperatures between -2 degrees C and 29 degrees C while methanogenesis was not detected. Bacterial diversity was high with 162 operational taxonomic units observed from 800 16S rDNA clone sequences. The 158 pure cultures isolated from the permafrost soil affiliated with 29 different bacterial genera, the majority of which have not previously been isolated from permafrost habitats. Most of the strains isolated were affiliated to the genera Cellulomonas and Arthrobacter and several of the pure cultures were closely related to bacteria reported from other cryohabitats. Characterization of viable bacterial communities in permafrost soils is important as it will enable identification of functionally important groups together with the as yet undescribed adaptations that bacteria have evolved for surviving subzero temperatures for millennia.

Aspergillus fumigatus viability drives allergic responses to inhaled conidia.

PubMed

Nayak, Ajay P; Croston, Tara L; Lemons, Angela R; Goldsmith, W T; Marshall, Nikki B; Kashon, Michael L; Germolec, Dori R; Beezhold, Donald H; Green, Brett J

2018-04-13

Aspergillus fumigatus induced allergic airway disease has been shown to involve conidial germination in vivo but the immunological mechanisms remain uncharacterized. A subchronic murine exposure model was used to examine the immunological mediators that are regulated in response to either culturable or non-culturable A. fumigatus conidia. Female B6C3F1/N mice were repeatedly dosed via inhalation with 1 x 105 viable or heat inactivated conidia (HIC), twice a week for 13 weeks (26 exposures). Control mice inhaled HEPA-filtered air. The influence of A. fumigatus conidial germination on the pulmonary immunopathological outcomes was evaluated by flow cytometry analysis of cellular infiltration in the airways, assessment of lung mRNA expression, and quantitative proteomics and histopathology of whole lung tissue. Repeated inhalation of viable conidia, but not HIC, resulted in allergic inflammation marked by vascular remodeling, extensive eosinophilia, and accumulation of alternatively activated macrophages (AAMs) in the murine airways. More specifically, mice that inhaled viable conidia resulted in a mixed TH1 and TH2 (IL-13) cytokine response. Recruitment of eosinophils corresponded with increased Ccl11 transcripts. Furthermore, genes associated with M2 or alternatively activated macrophage polarization (e.g. Arg1, Chil3 and Retnla) were significantly upregulated in viable A. fumigatus exposed mice. In mice inhaling HIC, CD4+ T cells expressing IFN-γ (TH1) dominated the lymphocytic infiltration. Quantitative proteomics of the lung revealed metabolic reprogramming accompanied by mitochondrial dysfunction and endoplasmic reticulum stress stimulated by oxidative stress from repetitive microbial insult. Our studies demonstrate that A. fumigatus conidial viability in vivo is critical to the immunopathological presentation of chronic fungal allergic disease. Copyright © 2018. Published by Elsevier Inc.

Annual Industrial Capabilities Report to Congress

DTIC Science & Technology

2009-03-01

thermal batteries . Military unique, high performance batteries are the only viable power source for many defense systems. The Missile Defense Agency...armor. Thermal Battery Production The objective of this Title III initiative is to strengthen and expand a domestic source for advanced

Free-electron laser emission architecture impact on extreme ultraviolet lithography

NASA Astrophysics Data System (ADS)

Hosler, Erik R.; Wood, Obert R.; Barletta, William A.

2017-10-01

Laser-produced plasma (LPP) EUV sources have demonstrated ˜125 W at customer sites, establishing confidence in EUV lithography (EUVL) as a viable manufacturing technology. However, for extension to the 3-nm technology node and beyond, existing scanner/source technology must enable higher-NA imaging systems (requiring increased resist dose and providing half-field exposures) and/or EUV multipatterning (requiring increased wafer throughput proportional to the number of exposure passes). Both development paths will require a substantial increase in EUV source power to maintain the economic viability of the technology, creating an opportunity for free-electron laser (FEL) EUV sources. FEL-based EUV sources offer an economic, high-power/single-source alternative to LPP EUV sources. Should FELs become the preferred next-generation EUV source, the choice of FEL emission architecture will greatly affect its operational stability and overall capability. A near-term industrialized FEL is expected to utilize one of the following three existing emission architectures: (1) self-amplified spontaneous emission, (2) regenerative amplifier, or (3) self-seeding. Model accelerator parameters are put forward to evaluate the impact of emission architecture on FEL output. Then, variations in the parameter space are applied to assess the potential impact to lithography operations, thereby establishing component sensitivity. The operating range of various accelerator components is discussed based on current accelerator performance demonstrated at various scientific user facilities. Finally, comparison of the performance between the model accelerator parameters and the variation in parameter space provides a means to evaluate the potential emission architectures. A scorecard is presented to facilitate this evaluation and provides a framework for future FEL design and enablement for EUVL applications.

The science, development, and commercialization of postharvest biocontrol products

USDA-ARS?s Scientific Manuscript database

Postharvest biological control agents as a viable alternative to the use of synthetic chemicals have been the focus of considerable research for the last 30 years by many scientists and several commercial companies worldwide. Several antagonists of postharvest pathogens have been identified and tes...

21st Century Water Asset Accounting - Case Studies Report (WERF Report INFR6R12a)

EPA Science Inventory

America’s decaying water infrastructure presents significant financial and logistical challenges for water utilities. Green infrastructure has been gaining traction as a viable alternative and complement to traditional “grey” infrastructure for water management. Current accounti...

Plug-In Electric Vehicle Handbook for Fleet Managers (Brochure)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2012-04-01

Plug-in electric vehicles (PEVs) are entering the automobile market and are viable alternatives to conventional vehicles. This guide for fleet managers describes the basics of PEV technology, PEV benefits for fleets, how to select the right PEV, charging a PEV, and PEV maintenance.

PROJECTING WILDLIFE RESPONSES TO ALTERNATIVE FUTURE LANDSCAPES IN OREGON'S WILLAMETTE VALLEY

EPA Science Inventory

Increasingly, environmental quality is becoming recognized as a critical factor that should constrain land use planning. One important measure of a landscape's quality is its capacity to support viable populations of wildlife species. But the ability of land managers to balance c...

DEMONSTRATION OF WATERBASED PLATEN ADHESIVES FOR GARMENT SCREEN PRINTERS

EPA Science Inventory

The paper discusses a demonstration of waterbased platen adhesives as a viable alternative to the organic-based aerosol adhesives that are predominantly used by garment screen printers to affix garments or fabric pieces to print platens. o demonstrate this, the effectiveness of s...

Development of a 1-m Class Telescope at TMF to Support Optical Communications Demonstrations

NASA Technical Reports Server (NTRS)

Wilson, K. E.; Sandusky, J.

1998-01-01

With the impetus towards high data rate communications in inter-satellite and space-to-ground links, the small size, low-mass, and low-power consumption of optical communications is seen as a viable alternative to radio frequency links.

76 FR 66758 - Remedies for Small Copyright Claims

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-27

... legal system hinders or prevents copyright owners from pursuing copyright infringement claims that have... helpful and viable. A. Challenges of the Current Legal System Currently, copyright owners interested in... Office is interested in learning about alternatives to the current legal system that might help alleviate...

Social Studies in the Nuclear Age: The Doomsday Issue.

ERIC Educational Resources Information Center

Kahn, Andrew Lerner

1984-01-01

A major nuclear exchange between America and the Soviet Union would probably result in the total annihilation of humankind. Social studies educators have a special responsibility to their students to search out all viable alternatives to nuclear deterrence and to make them known. (RM)

Online 1990.

ERIC Educational Resources Information Center

Goldstein, Morris

This paper examines the co-existence of online and CD-ROM technologies in terms of their existing pricing structures, marketing strategies, functionality, and future roles. "Fixed Price Unlimited Usage" (FPUU) pricing and flat-rate pricing are discussed as viable alternatives to current pricing practices. In addition, it is argued that the…

Wireless global positioning system fleet tracking system at the University at Albany.

DOT National Transportation Integrated Search

2014-07-01

This report provides an overview of the project undertaken at the University at Albany to make alternative transportation a more : viable option by implementing a GPS Tracking System on the University bus fleet and broadcasting the bus locations to c...

Microsilica modified concrete for bridge deck overlays : first-year interim report.

DOT National Transportation Integrated Search

1991-11-01

The study objective was to see if microsilica concrete (MC) is a viable alternative to the latex modified concrete (LMC) usually used on bridge deck overlays in Oregon. The study addresses MC overlays placed in 1989 on 7 portland cement concrete (PCC...

Public Education in Rural America.

ERIC Educational Resources Information Center

Sher, Jonathan P.; And Others

Like agriculture, public education in rural America has increasingly moved away from a small community orientation to larger consolidations. The forces of modernization, consolidation, and urbanization challenge the rural community to create a pragmatically viable alternative to the metropolitan way of life, because by adopting urban practices and…

A technique for lyopreservation of Clostridium ljungdahlii in a biocomposite matrix for CO absorption

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schulte, Mark J.; Solocinski, Jason; Wang, Mian

A system capable of biocatalytic conversion of distributed sources of single carbon gases such as carbon monoxide into hydrocarbons can be highly beneficial for developing commercially viable biotechnology applications in alternative energy. Several anaerobic bacterial strains can be used for such conversion. The anaerobic carbon monoxide-fixing bacteria Clostridium ljungdahlii OTA1 is a model CO assimilating microorganism that currently requires cryogenic temperature for storage of the viable strains. If these organisms can be stabilized and concentrated in thin films in advanced porous materials, it will enable development of high gas fraction, biocomposite absorbers with elevated carbon monoxide (CO) mass transfer rate,more » that require minimal power input and liquid, and demonstrate elevated substrate consumption rate compared to conventional suspended cell bioreactors. We report development of a technique for dry-stabilization of C. ljungdahlii OTA1 on a paper biocomposite. Bacterial samples coated onto paper were desiccated in the presence of trehalose using convective drying and stored at 4°C. Optimal dryness was ~1g H 2O per gram of dry weight (g DW). CO uptake directly following biocomposite rehydration steadily increases over time indicating immediate cellular metabolic recovery. A high-resolution Raman microspectroscopic hyperspectral imaging technique was employed to spatially quantify the residual moisture content. We have demonstrated for the first time that convectively dried and stored C. ljungdahlii strains were stabilized in a desiccated state for over 38 days without a loss in CO absorbing reactivity. The Raman hyperspectral imaging technique described here is a non-invasive characterization tool to support development of dry-stabilization techniques for microorganisms on inexpensive porous support materials. In conclusion, the present study successfully extends and implements the principles of dry-stabilization for preservation of strictly anaerobic bacteria as an alternative to lyophilization or spray drying that could enable centralized biocomposite biocatalyst fabrication and decentralized bioprocessing of CO to liquid fuels or chemicals.« less

A technique for lyopreservation of Clostridium ljungdahlii in a biocomposite matrix for CO absorption

DOE PAGES

Schulte, Mark J.; Solocinski, Jason; Wang, Mian; ...

2017-07-05

A system capable of biocatalytic conversion of distributed sources of single carbon gases such as carbon monoxide into hydrocarbons can be highly beneficial for developing commercially viable biotechnology applications in alternative energy. Several anaerobic bacterial strains can be used for such conversion. The anaerobic carbon monoxide-fixing bacteria Clostridium ljungdahlii OTA1 is a model CO assimilating microorganism that currently requires cryogenic temperature for storage of the viable strains. If these organisms can be stabilized and concentrated in thin films in advanced porous materials, it will enable development of high gas fraction, biocomposite absorbers with elevated carbon monoxide (CO) mass transfer rate,more » that require minimal power input and liquid, and demonstrate elevated substrate consumption rate compared to conventional suspended cell bioreactors. We report development of a technique for dry-stabilization of C. ljungdahlii OTA1 on a paper biocomposite. Bacterial samples coated onto paper were desiccated in the presence of trehalose using convective drying and stored at 4°C. Optimal dryness was ~1g H 2O per gram of dry weight (g DW). CO uptake directly following biocomposite rehydration steadily increases over time indicating immediate cellular metabolic recovery. A high-resolution Raman microspectroscopic hyperspectral imaging technique was employed to spatially quantify the residual moisture content. We have demonstrated for the first time that convectively dried and stored C. ljungdahlii strains were stabilized in a desiccated state for over 38 days without a loss in CO absorbing reactivity. The Raman hyperspectral imaging technique described here is a non-invasive characterization tool to support development of dry-stabilization techniques for microorganisms on inexpensive porous support materials. In conclusion, the present study successfully extends and implements the principles of dry-stabilization for preservation of strictly anaerobic bacteria as an alternative to lyophilization or spray drying that could enable centralized biocomposite biocatalyst fabrication and decentralized bioprocessing of CO to liquid fuels or chemicals.« less

Effect of Induced Pluripotent Stem Cell Technology in Blood Banking

PubMed Central

Focosi, Daniele

2016-01-01

Summary Population aging has imposed cost-effective alternatives to blood donations. Artificial blood is still at the preliminary stages of development, and the need for viable cells seems unsurmountable. Because large numbers of viable cells must be promptly available for clinical use, stem cell technologies, expansion, and banking represent ideal tools to ensure a regular supply. Provided key donors can be identified, induced pluripotent stem cell (iPSC) technology could pave the way to a new era in transfusion medicine, just as it is already doing in many other fields of medicine. The present review summarizes the current state of research on iPSC technology in the field of blood banking, highlighting hurdles, and promises. Significance The aging population in Western countries is causing a progressive reduction of blood donors and a constant increase of blood recipients. Because blood is the main therapeutic option to treat acute hemorrhage, cost-effective alternatives to blood donations are being actively investigated. The enormous replication capability of induced pluripotent stem cells and their promising results in many other fields of medicine could be an apt solution to produce the large numbers of viable cells required in transfusion and usher in a new era in transfusion medicine. The present report describes the potentiality, technological hurdles, and promises of induced pluripotent stem cells to generate red blood cells by redifferentiation. PMID:26819256

Laser assisted deposition

NASA Technical Reports Server (NTRS)

Dutta, S.

1983-01-01

Applications of laser-based processing techniques to solar cell metallization are discussed. Laser-assisted thermal or photolytic maskless deposition from organometallic vapors or solutions may provide a viable alternative to photovoltaic metallization systems currently in use. High power, defocused excimer lasers may be used in conjunction with masks as an alternative to direct laser writing to provide higher throughput. Repeated pulsing with excimer lasers may eliminate the need for secondary plating techniques for metal film buildup. A comparison between the thermal and photochemical deposition processes is made.

Emergent Rules for Codon Choice Elucidated by Editing Rare Arginine Codons in Escherichia coli

DTIC Science & Technology

2016-09-20

alternative codons are more likely to be viable. To evaluate synonymous and nonsynonymous alternatives to essential AGRs further, we imple- mented a CRISPR ... Crispr -assisted MAGE). First, we designed oligos that changed not only the target AGR codon to NNN but also made several synonymous changes at least 50...nt downstream that would disrupt a 20-bp CRISPR target lo- cus. MAGE was used to replace each AGR with NNN in parallel, and CRISPR /cas9 was used to

Alternative Dispute Resolution : A Viable Method for Settling Government Contract Disputes

DTIC Science & Technology

1993-06-01

S. Rept. 543, 101st Congress, 2d Session. 14. Page, Reba and Lees, Frederick J., "Roles of Participants in Mini-Trial," Public Contract Law Journal...15. Brittin, Alexander J., "Alternative Dispute Resolution in Government Contract Appeals," Public Contract Law Journal. 16. Dauer, "Litigation v...International Law and Economics. Vol. 20, No. 3, 1987. 22. Page, Reba and Lees, Frederick J., "Roles of Participants in Mini-Trial," Public Contract Law Journal

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

PubMed Central

Napolitano, Michael G.; Landon, Matthieu; Gregg, Christopher J.; Lajoie, Marc J.; Govindarajan, Lakshmi; Mosberg, Joshua A.; Kuznetsov, Gleb; Goodman, Daniel B.; Vargas-Rodriguez, Oscar; Isaacs, Farren J.; Söll, Dieter; Church, George M.

2016-01-01

The degeneracy of the genetic code allows nucleic acids to encode amino acid identity as well as noncoding information for gene regulation and genome maintenance. The rare arginine codons AGA and AGG (AGR) present a case study in codon choice, with AGRs encoding important transcriptional and translational properties distinct from the other synonymous alternatives (CGN). We created a strain of Escherichia coli with all 123 instances of AGR codons removed from all essential genes. We readily replaced 110 AGR codons with the synonymous CGU codons, but the remaining 13 “recalcitrant” AGRs required diversification to identify viable alternatives. Successful replacement codons tended to conserve local ribosomal binding site-like motifs and local mRNA secondary structure, sometimes at the expense of amino acid identity. Based on these observations, we empirically defined metrics for a multidimensional “safe replacement zone” (SRZ) within which alternative codons are more likely to be viable. To evaluate synonymous and nonsynonymous alternatives to essential AGRs further, we implemented a CRISPR/Cas9-based method to deplete a diversified population of a wild-type allele, allowing us to evaluate exhaustively the fitness impact of all 64 codon alternatives. Using this method, we confirmed the relevance of the SRZ by tracking codon fitness over time in 14 different genes, finding that codons that fall outside the SRZ are rapidly depleted from a growing population. Our unbiased and systematic strategy for identifying unpredicted design flaws in synthetic genomes and for elucidating rules governing codon choice will be crucial for designing genomes exhibiting radically altered genetic codes. PMID:27601680

Low power energy harvesting and storage techniques from ambient human powered energy sources

NASA Astrophysics Data System (ADS)

Yildiz, Faruk

Conventional electrochemical batteries power most of the portable and wireless electronic devices that are operated by electric power. In the past few years, electrochemical batteries and energy storage devices have improved significantly. However, this progress has not been able to keep up with the development of microprocessors, memory storage, and sensors of electronic applications. Battery weight, lifespan and reliability often limit the abilities and the range of such applications of battery powered devices. These conventional devices were designed to be powered with batteries as required, but did not allow scavenging of ambient energy as a power source. In contrast, development in wireless technology and other electronic components are constantly reducing the power and energy needed by many applications. If energy requirements of electronic components decline reasonably, then ambient energy scavenging and conversion could become a viable source of power for many applications. Ambient energy sources can be then considered and used to replace batteries in some electronic applications, to minimize product maintenance and operating cost. The potential ability to satisfy overall power and energy requirements of an application using ambient energy can eliminate some constraints related to conventional power supplies. Also power scavenging may enable electronic devices to be completely self-sustaining so that battery maintenance can eventually be eliminated. Furthermore, ambient energy scavenging could extend the performance and the lifetime of the MEMS (Micro electromechanical systems) and portable electronic devices. These possibilities show that it is important to examine the effectiveness of ambient energy as a source of power. Until recently, only little use has been made of ambient energy resources, especially for wireless networks and portable power devices. Recently, researchers have performed several studies in alternative energy sources that could provide small amounts of electricity to low-power electronic devices. These studies were focused to investigate and obtain power from different energy sources, such as vibration, light, sound, airflow, heat, waste mechanical energy and temperature variations. This research studied forms of ambient energy sources such as waste mechanical (rotational) energy from hydraulic door closers, and fitness exercise bicycles, and its conversion and storage into usable electrical energy. In both of these examples of applications, hydraulic door closers and fitness exercise bicycles, human presence is required. A person has to open the door in order for the hydraulic door closer mechanism to function. Fitness exercise bicycles need somebody to cycle the pedals to generate electricity (while burning calories.) Also vibrations, body motions, and compressions from human interactions were studied using small piezoelectric fiber composites which are capable of recovering waste mechanical energy and converting it to useful electrical energy. Based on ambient energy sources, electrical energy conversion and storage circuits were designed and tested for low power electronic applications. These sources were characterized according to energy harvesting (scavenging) methods, and power and energy density. At the end of the study, the ambient energy sources were matched with possible electronic applications as a viable energy source.

MAMMALIAN APOPTOSIS IN WHOLE NEONATAL OVARIES, EMBRYOS AND FETAL LIMBS USING CONFOCAL MICROSCOPY

EPA Science Inventory

The emergence of confocal laser scanning microscopy (CLSM) as a technique capable of optically generating serial sections of whole-mount tissue and then reassembling the computer-stored images as a virtual 3-dimensional structure offers a viable alternative to traditional section...

Clean Cities Plug-In Electric Vehicle Handbook for Fleet Managers

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2012-04-01

Plug-in electric vehicles (PEVs) are entering the automobile market and are viable alternatives to conventional vehicles. This guide for fleet managers describes the basics of PEV technology, PEV benefits for fleets, how to select the right PEV, charging a PEV, and PEV maintenance.

Furfural Induces Reactive Oxygen Species Accumulation and Cellular Damage in Saccharomyces Cerevisiae

USDA-ARS?s Scientific Manuscript database

Background: Biofuels offer a viable alternative to petroleum-based fuel. However, current methods are not sufficient and technology to use lignocellulosic biomass as a fermentation substrate faces several challenges. One challenge is the need of a robust fermentative microorganism that can tolera...

Web-Based Training. ERIC Digest No. 218.

ERIC Educational Resources Information Center

Brown, Bettina Lankard

Reduced training costs, worldwide accessibility, and improved technological capabilities have made Web-based training (WBT) a viable alternative to classroom instruction. WBT enables businesses to cut their training costs. Efficiency of operation is another major advantage of WBT. The flexibility of time, place, and programs offered via WBT…

In Response to Rowland on "Realism and Debateability in Policy Advocacy."

ERIC Educational Resources Information Center

Herbeck, Dale A.; Katsulas, John P.

1986-01-01

Argues that Robert Rowland has overstated the case against the permutation process for assessing counterplan competitiveness. Claims that the permutation standard is a viable method for ascertaining counterplan competitiveness. Examines Rowland's alternative and argues that it is an unsatisfactory method for determining counterplan…

Understanding commuter patterns and behavior : an analysis to recommend policies aimed at reducing vehicle use.

DOT National Transportation Integrated Search

2010-08-01

The objective of the study was to make alternative transportation a more viable option by identifying commuting preferences and patterns in order to recommend policies aimed at reducing vehicle miles travelled. This study focused on the use of single...

Culture-Specific Testing: Part 1.

ERIC Educational Resources Information Center

Williams, Robert L., Ed.

1981-01-01

In five articles provides a rationale for the development of culturally specific tests, presents research on their use, and discusses clinical uses. Focuses on two Afro-centric projective tests: The Thematic Apperception Test and Themes Concerning Blacks. Criticizes use of traditional projective tests and points out viable alternatives. (JAC)

Alternative Test Methods for Developmental Neurotoxicity: A History and Path Forward (OECD EFSA workshop)

EPA Science Inventory

Exposure to environmental contaminants is well documented to adversely impact the development of the nervous system. However, the time, animal and resource intensive EPA and OECD testing guideline methods for developmental neurotoxicity (DNT) are not a viable solution to characte...

Physical and Economic Integration of Carbon Capture Methods with Sequestration Sinks

NASA Astrophysics Data System (ADS)

Murrell, G. R.; Thyne, G. D.

2007-12-01

Currently there are several different carbon capture technologies either available or in active development for coal- fired power plants. Each approach has different advantages, limitations and costs that must be integrated with the method of sequestration and the physiochemical properties of carbon dioxide to evaluate which approach is most cost effective. For large volume point sources such as coal-fired power stations, the only viable sequestration sinks are either oceanic or geological in nature. However, the carbon processes and systems under consideration produce carbon dioxide at a variety of pressure and temperature conditions that must be made compatible with the sinks. Integration of all these factors provides a basis for meaningful economic comparisons between the alternatives. The high degree of compatibility between carbon dioxide produced by integrated gasification combined cycle technology and geological sequestration conditions makes it apparent that this coupling currently holds the advantage. Using a basis that includes complete source-to-sink sequestration costs, the relative cost benefit of pre-combustion IGCC compared to other post-combustion methods is on the order of 30%. Additional economic benefits arising from enhanced oil recovery revenues and potential sequestration credits further improve this coupling.

Progress in the development of PDF turbulence models for combustion

NASA Technical Reports Server (NTRS)

Hsu, Andrew T.

1991-01-01

A combined Monte Carlo-computational fluid dynamic (CFD) algorithm was developed recently at Lewis Research Center (LeRC) for turbulent reacting flows. In this algorithm, conventional CFD schemes are employed to obtain the velocity field and other velocity related turbulent quantities, and a Monte Carlo scheme is used to solve the evolution equation for the probability density function (pdf) of species mass fraction and temperature. In combustion computations, the predictions of chemical reaction rates (the source terms in the species conservation equation) are poor if conventional turbulence modles are used. The main difficulty lies in the fact that the reaction rate is highly nonlinear, and the use of averaged temperature produces excessively large errors. Moment closure models for the source terms have attained only limited success. The probability density function (pdf) method seems to be the only alternative at the present time that uses local instantaneous values of the temperature, density, etc., in predicting chemical reaction rates, and thus may be the only viable approach for more accurate turbulent combustion calculations. Assumed pdf's are useful in simple problems; however, for more general combustion problems, the solution of an evolution equation for the pdf is necessary.

Microalgae as sustainable renewable energy feedstock for biofuel production.

PubMed

Medipally, Srikanth Reddy; Yusoff, Fatimah Md; Banerjee, Sanjoy; Shariff, M

2015-01-01

The world energy crisis and increased greenhouse gas emissions have driven the search for alternative and environmentally friendly renewable energy sources. According to life cycle analysis, microalgae biofuel is identified as one of the major renewable energy sources for sustainable development, with potential to replace the fossil-based fuels. Microalgae biofuel was devoid of the major drawbacks associated with oil crops and lignocelluloses-based biofuels. Algae-based biofuels are technically and economically viable and cost competitive, require no additional lands, require minimal water use, and mitigate atmospheric CO2. However, commercial production of microalgae biodiesel is still not feasible due to the low biomass concentration and costly downstream processes. The viability of microalgae biodiesel production can be achieved by designing advanced photobioreactors, developing low cost technologies for biomass harvesting, drying, and oil extraction. Commercial production can also be accomplished by improving the genetic engineering strategies to control environmental stress conditions and by engineering metabolic pathways for high lipid production. In addition, new emerging technologies such as algal-bacterial interactions for enhancement of microalgae growth and lipid production are also explored. This review focuses mainly on the problems encountered in the commercial production of microalgae biofuels and the possible techniques to overcome these difficulties.

Recent advances on enzymatic glucose/oxygen and hydrogen/oxygen biofuel cells: Achievements and limitations

NASA Astrophysics Data System (ADS)

Cosnier, Serge; J. Gross, Andrew; Le Goff, Alan; Holzinger, Michael

2016-09-01

The possibility of producing electrical power from chemical energy with biological catalysts has induced the development of biofuel cells as viable energy sources for powering portable and implanted electronic devices. These power sources employ biocatalysts, called enzymes, which are highly specific and catalytic towards the oxidation of a biofuel and the reduction of oxygen or hydrogen peroxide. Enzymes, on one hand, are promising candidates to replace expensive noble metal-based catalysts in fuel cell research. On the other hand, they offer the exciting prospect of a new generation of fuel cells which harvest energy from body fluids. Biofuel cells which use glucose as a fuel are particularly interesting for generating electricity to power electronic devices inside a living body. Hydrogen consuming biofuel cells represent an emerging alternative to platinum catalysts due to comparable efficiencies and the capability to operate at lower temperatures. Currently, these technologies are not competitive with existing commercialised fuel cell devices due to limitations including insufficient power outputs and lifetimes. The advantages and challenges facing glucose biofuel cells for implantation and hydrogen biofuel cells will be summarised along with recent promising advances and the future prospects of these exotic energy-harvesting devices.

Impacts of black carbon and co-pollutant emissions from transportation sector in Mexico City

NASA Astrophysics Data System (ADS)

Zavala, Miguel; Almanza, Victor; Garcia, Agustin; Jazcilevich, Aron; Lei, Wenfang; Molina, Luisa

2016-04-01

Black carbon is one of the most important short-lived climate-forcing agents, which is harmful to human health and also contributes significantly to climate change. Transportation is one of the largest sources of black carbon emissions in many megacities and urban complexes, with diesel vehicles leading the way. Both on-road and off-road vehicles can emit substantial amounts of harmful BC-containing particulate matter (PM) and are also responsible for large emissions of carbon dioxide (CO2), carbon monoxide (CO), nitrogen oxides (NOx), and many other co-emitted volatile organic compounds (VOCs). Regionally, black carbon emissions contributions from mobile sources may vary widely depending on the technical characteristics of the vehicle fleet, the quality and chemical properties of the fuels consumed, and the degree of local development and economic activities that foster wider and more frequent or intensive use of vehicles. This presentation will review and assess the emissions of black carbon from the on-road and off-road transportation sector in the Mexico City Metropolitan Area. Viable mitigation strategies, including innovative technological alternatives to reduce black carbon and co-pollutants in diesel vehicles and their impacts on climate, human health and ecosystems will be described.

Performance of a nonlaser light source for photodynamic therapy

NASA Astrophysics Data System (ADS)

Whitehurst, Colin; Byrne, Karen T.; Morton, Colin; Moore, James V.

1995-03-01

Advances in short arc technology and optical filter coatings led to the design and construction of a table-top light source in 1989; the first viable and cost-effective alternative to a laser. The device can deliver over 3 W within a 30 nm band centered at any wavelength from 200 nm to 1200 nm at fluence rates of over 1 W cm-2. Its relative biological effectiveness (RBE) in vitro has been proven alongside an argon pumped dye laser and a copper vapor pumped dye laser. These in vitro tests showed an efficiency of hematoporphyrin derivative (HPD) induced cellular photoinactivation close to that of the argon/dye laser (RBE 100%), with a mean RBE for the lamp of 87 +/- 3% (p < 0.05). The lamp proved to be superior to that of the copper/dye laser system with an RBE of up to 150% at fluence rates above 50 mWcm-2. In vivo tests show that the extent and depth of tumor necrosis are comparable to that of an argon/dye laser. An in situ bioassay using tumor regrowth delay is currently underway. Early clinical trials show clearance of Bowen's disease and actinic keratosis using the same light fluences as costly PDT lasers.

ED-XRF spectrometry-based comparative inorganic profile of leaf-derived in vitro calli and in vivo leaf samples of Phyllanthus amarus Schum. & Thonn.--a hepatoprotective herb.

PubMed

Nayak, P; Behera, P R; Thirunavoukkarasu, M; Chand, P K

2011-03-01

The Energy Dispersive X-ray Fluorescence (ED-XRF) set-up incorporating a molybdenum secondary exciter was used for quantitative determination of major and minor elements in leaves of in vivo grown medicinal herb Phyllanthus amarus vis-á-vis its leaf-derived in vitro callus culture. The elements such as K, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Se, Rb, Sr and Pb were identified, quantified and compared between both the sources. Experimental results revealed that, compared to the naturally grown herb, in vitro leaf-derived callus cultures were more efficient in accumulating inorganic elements, especially trace elements, which are essential for growth and development and more importantly for prevention and cure of diseases. This investigation on a medicinal plant species is the first of its kind to have used the ED-XRF technique to demonstrate a comparative account of the elemental profile of in vitro callus cultures with their in vivo donor in order to explore the possibility of exploiting the former as a viable alternative and a renewable source of phytochemicals. Copyright © 2010 Elsevier Ltd. All rights reserved.

Isolation, characterization, and differentiation of stem cells for cartilage regeneration.

PubMed

Beane, Olivia S; Darling, Eric M

2012-10-01

The goal of tissue engineering is to create a functional replacement for tissues damaged by injury or disease. In many cases, impaired tissues cannot provide viable cells, leading to the investigation of stem cells as a possible alternative. Cartilage, in particular, may benefit from the use of stem cells since the tissue has low cellularity and cannot effectively repair itself. To address this need, researchers are investigating the chondrogenic capabilities of several multipotent stem cell sources, including adult and extra-embryonic mesenchymal stem cells (MSCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). Comparative studies indicate that each cell type has advantages and disadvantages, and while direct comparisons are difficult to make, published data suggest some sources may be more promising for cartilage regeneration than others. In this review, we identify current approaches for isolating and chondrogenically differentiating MSCs from bone marrow, fat, synovium, muscle, and peripheral blood, as well as cells from extra-embryonic tissues, ESCs, and iPSCs. Additionally, we assess chondrogenic induction with growth factors, identifying standard cocktails used for each stem cell type. Cell-only (pellet) and scaffold-based studies are also included, as is a discussion of in vivo results.

Angiographic evaluation and management of acute gastrointestinal hemorrhage

PubMed Central

Walker, T Gregory; Salazar, Gloria M; Waltman, Arthur C

2012-01-01

Although most cases of acute nonvariceal gastrointestinal hemorrhage either spontaneously resolve or respond to medical management or endoscopic treatment, there are still a significant number of patients who require emergency angiography and transcatheter treatment. Evaluation with noninvasive imaging such as nuclear scintigraphy or computed tomography may localize the bleeding source and/or confirm active hemorrhage prior to angiography. Any angiographic evaluation should begin with selective catheterization of the artery supplying the most likely site of bleeding, as determined by the available clinical, endoscopic and imaging data. If a hemorrhage source is identified, superselective catheterization followed by transcatheter microcoil embolization is usually the most effective means of successfully controlling hemorrhage while minimizing potential complications. This is now well-recognized as a viable and safe alternative to emergency surgery. In selected situations transcatheter intra-arterial infusion of vasopressin may also be useful in controlling acute gastrointestinal bleeding. One must be aware of the various side effects and potential complications associated with this treatment, however, and recognize the high re-bleeding rate. In this article we review the current role of angiography, transcatheter arterial embolization and infusion therapy in the evaluation and management of nonvariceal gastrointestinal hemorrhage. PMID:22468082

Microalgae as Sustainable Renewable Energy Feedstock for Biofuel Production

PubMed Central

Yusoff, Fatimah Md.; Shariff, M.

2015-01-01

The world energy crisis and increased greenhouse gas emissions have driven the search for alternative and environmentally friendly renewable energy sources. According to life cycle analysis, microalgae biofuel is identified as one of the major renewable energy sources for sustainable development, with potential to replace the fossil-based fuels. Microalgae biofuel was devoid of the major drawbacks associated with oil crops and lignocelluloses-based biofuels. Algae-based biofuels are technically and economically viable and cost competitive, require no additional lands, require minimal water use, and mitigate atmospheric CO2. However, commercial production of microalgae biodiesel is still not feasible due to the low biomass concentration and costly downstream processes. The viability of microalgae biodiesel production can be achieved by designing advanced photobioreactors, developing low cost technologies for biomass harvesting, drying, and oil extraction. Commercial production can also be accomplished by improving the genetic engineering strategies to control environmental stress conditions and by engineering metabolic pathways for high lipid production. In addition, new emerging technologies such as algal-bacterial interactions for enhancement of microalgae growth and lipid production are also explored. This review focuses mainly on the problems encountered in the commercial production of microalgae biofuels and the possible techniques to overcome these difficulties. PMID:25874216

Survey of Contamination in Fuel Tanks of DD-963 Class Ships.

DTIC Science & Technology

1982-07-23

and Identifly by block num0b.’) Diesel fuel Fuel sludge Bacteria Fuel contamination Cladosporium resinae Sludge composition assess sources of... resinae ) predominated. Viable sulfate reducers were sometimes present but rarely sulfide. Below pH 4 bacteria were rare and fungi and yeasts were numerous...but the variety tended to be restricted to C. resinae and Candida. Differences in viable microbial varieties present in these sludge categories are

Bioaerosol assessment in naturally ventilated historical library building with restricted personnel access.

PubMed

Harkawy, Aleksander; Górny, Rafał L; Ogierman, Leonard; Wlazło, Agnieszka; Ławniczek-Wałczyk, Anna; Niesler, Anna

2011-01-01

The aim of this study was to check the degree and identify the sources of microbial contamination of the Jasna Gora (Bright Hill) monastery library 10 years after disinfection of the incunabula collection. The registered maximum viable indoor microbial concentrations were 1,875 and 7,100 cfu/m³ for stationary and personal measurements, whereas respective total concentrations were 71,000 and 100,000 counts/m3. There was no statistically significant difference between the concentrations of viable microorganisms measured in the stationary using Andersen, GSP, and Button samplers. Moreover, GSP and Button samplers can be interchangeably applied when viable or total microbial levels are stationary or personally measured. The culturable microorganisms constituted 0.5 - 3.9% of the total microflora only. Filamentous fungi were the most prevalent outdoors, whereas Gram-positive cocci and endospore forming Gram-positive rods dominated indoors in the air and settled dust, respectively. Hence, an unrestrained infiltration of ambient air through the draughtiness of the building envelope is probably the main process responsible for indoor fungal pollution, whereas bacterial contaminants have their major sources in the indoor environment. Moreover, even a chemically cleansed library collection, having a restricted personnel access, but under the influence of ambient air, can undergo microbial contamination and becomes an important microbial emission source.

Montana BioDiesel Initiative

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peyton, Brent

This initiative funding helped put Montana State University (MSU) in a position to help lead in the development of biodiesel production strategies. Recent shortages in electrical power and rising gasoline prices have focused much attention on the development of alternative energy sources that will end our dependence on fossil fuels. In addition, as the concern for environmental impact of utilizing fossil fuels increases, effective strategies must be implemented to reduce emissions or the increased regulations imposed on fossil fuel production will cause economic barriers for their use to continue to increase. Biodiesel has been repeatedly promoted as a more environmentallymore » sound and renewable source of fuel and may prove to be a highly viable solution to provide, at the least, a proportion of our energy needs. Currently there are both practical and economic barriers to the implementation of alternative energy however the advent of these technologies is inevitable. Since many of the same strategies for the storage, transport, and utilization of biodiesel are common with that of fossil fuels, the practical barriers for biodiesel are comparatively minimal. Strategies were developed to harness the CO 2 as feedstock to support the growth of biodiesel producing algae. The initiative funding led to the successful funding of highly rated projects in competitive national grant programs in the National Science Foundation and the Department of Energy. This funding put MSU in a key position to develop technologies to utilize the CO 2 rich emissions produced in fossil fuel utilization and assembled world experts concerning the growth characteristics of photosynthetic microorganisms capable of producing biodiesel.« less

The Effect of Growth Environment and Salinity on Lipid Production and Composition of Salicornia virginica

NASA Technical Reports Server (NTRS)

Bomani, Bilal Mark McDowell; Link, Dirk; Kail, Brian; Morreale, Bryan; Lee, Eric S.; Gigante, Bethany M.; Hendricks, Robert C.

2014-01-01

Finding a viable and sustainable source of renewable energy is a global task. Biofuels as a renewable energy source can potentially be a viable option for sustaining long-term energy needs. Biodiesel from halophytes shows great promise due to their ability to serve not only as a fuel source, but a food source as well. Halophytes are one of the few biomass plant species that can tolerate a wide range of saline conditions. We investigate the feasibility of using the halophyte, Salicornia virginica as a biofuel source by conducting a series of experiments utilizing various growth and salinity conditions. The goal is to determine if the saline content of Salicornia virginica in our indoor growth vs outdoor growth conditions has an influence on lipid recovery and total biomass composition. We focused on using standard lipid extraction protocols and characterization methods to evaluate twelve Salicornia virginica samples under six saline values ranging from freshwater to seawater and two growth conditions. The overall goal is to develop an optimal lipid extraction protocol for Salicornia virginica and potentially apply this protocol to halophytes in general.

Application of Traditional Chinese Herbal Medicine By-products as Dietary Feed Supplements and Antibiotic Replacements in Animal Production.

PubMed

Abdallah, Abedin; Zhang, Pei; Zhong, Qingzhen; Sun, Zewei

2018-05-22

Misuse of synthetic antibiotics in livestock leads to the transfer of antibiotic resistant pathogens into humans and deposits toxic residues in meat and milk. There is therefore an urgent need for safe and viable alternative approaches to improve the nutrition and wellbeing of farm animals. An alternative source that has been widely exploited is traditional Chinese herbal medicine (TCHM). These herbal medicines are an important part of the healthcare system in many Asian countries. Such herbs contain several but less toxic bioactive compounds which are generally regarded biodegradable. Recently, advances in knowledge on the importance of TCHM have led to a rapid increase in its production and hence, increasing the amount of by-products generated. Such by-products have become a serious environmental challenge because producers regard them as industrial waste and discard them directly. Incorporating TCHM by-products as feed additives to improve animal health and nutrition has been proposed because they contain high amounts of bioactive compounds which confer several health benefits to animals. TCHM by-products as feed additives apart from being a good alternative for synthetic antibiotics could also minimize the current environmental challenges associated with its disposal. This review summarizes scientific findings on the bioactive compounds in TCHM and TCHM by-products, discusses functional dietary patterns and outlines challenges that may hinder full utilization of TCHM by-products in animal production. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Single-Case Experimental Designs: A Systematic Review of Published Research and Current Standards

ERIC Educational Resources Information Center

Smith, Justin D.

2012-01-01

This article systematically reviews the research design and methodological characteristics of single-case experimental design (SCED) research published in peer-reviewed journals between 2000 and 2010. SCEDs provide researchers with a flexible and viable alternative to group designs with large sample sizes. However, methodological challenges have…

The Latent Variable Approach as Applied to Transitive Reasoning

ERIC Educational Resources Information Center

Bouwmeester, Samantha; Vermunt, Jeroen K.; Sijtsma, Klaas

2012-01-01

We discuss the limitations of hypothesis testing using (quasi-) experiments in the study of cognitive development and suggest latent variable modeling as a viable alternative to experimentation. Latent variable models allow testing a theory as a whole, incorporating individual differences with respect to developmental processes or abilities in the…

Community outreach: rural mobile health unit.

PubMed

Alexy, B B; Elnitsky, C A

1996-12-01

With the increased emphasis on cost containment, hospital administrators are investigating community outreach projects to remain economically viable. The authors describe the planning and implementation of a mobile health unit for rural elderly residents. This project represents an alternative model of healthcare delivery in a rural area with limited resources and healthcare providers.

Simulated and Virtual Science Laboratory Experiments: Improving Critical Thinking and Higher-Order Learning Skills

ERIC Educational Resources Information Center

Simon, Nicole A.

2013-01-01

Virtual laboratory experiments using interactive computer simulations are not being employed as viable alternatives to laboratory science curriculum at extensive enough rates within higher education. Rote traditional lab experiments are currently the norm and are not addressing inquiry, Critical Thinking, and cognition throughout the laboratory…

Hydrogenated cottonseed oil as raw material for biobased materials

USDA-ARS?s Scientific Manuscript database

There has been a lot of recent interest in using vegetable oils as biodegradable and renewable raw materials for the syntheses of various biobased materials. Although most of the attention has been paid to soybean oil thus far, cottonseed oil is a viable alternative. An advantage of cottonseed oil...

The Impact of Microcomputers on Composition Students.

ERIC Educational Resources Information Center

Hocking, Joan

To determine whether computer assisted instruction was just a fad or a viable alternative to traditional methods for teaching English composition, a microcomputer was used in a traditional college freshman English course. The class was divided into small groups: some went to the computer lab, while others worked in the classroom. Interactive…

New Challenges in Cross Domain Deterrence

DTIC Science & Technology

2018-06-01

Active and Passive Prior Refutation of Same and Alternative Counterarguments,” Journal of Abnormal Psychology , Vol. 63, No. 2, 1961. Miller, S. E., and...affordability, and maintaining the integrity of U.S. values may, in the end, cause punishment to be the only viable option. 92 For the concept of

Use of liquid/supercritical CO2 extraction process for butanol recovery from fermentation broth

USDA-ARS?s Scientific Manuscript database

In order for butanol fermentation to be a viable option, it is essential to recover it from fermentation broth using economical alternate in-situ product recovery techniques such as liquid/supercritical CO2 extraction as compared to distillation. This technique (liquid CO2 extraction & supercritical...

Hands-On Hydroponics

ERIC Educational Resources Information Center

Carver, Jeffrey; Wasserman, Bradley

2012-01-01

Hydroponics is a process in which plants are grown using nutrient-rich water instead of soil. Because this process maximizes the use of water and nutrients--providing only what the plant uses in controlled and easily maintained systems--it is a viable alternative to traditional farming methods. The amount of control in these systems also ensures…

RESEARCH PROJECT -- PERMEABLE REACTIVE BARRIERS FOR REMEDIATION OF CONTAMINATED GROUNDWATERS(SUBSURFACE PROTECTION AND REMEDIATION DIVISION, (NRMRL)

EPA Science Inventory

Permeable reactive barrier (PRB) technology is gradually being accepted as a viable alternative to conventional groundwater remediation systems such as pump and treat. PRB technology involves the placement or formation of a reactive treatment zone in the path of a dissolved conta...

Technology-Based Literacy Instruction for English Language Learners

ERIC Educational Resources Information Center

White, Erin L.; Gillard, Sharlett

2011-01-01

There is a growing need to implement an alternative and viable solution in U.S. K-12 schools that will address the ever-growing gap that the rapidly growing English language learner (ELL) population presents. This article examines various technology-based solutions, and their potential impact. The systematic implementation of these…

Can Higher Education Stimulate Entrepreneurial Intentions among Engineering and Business Students?

ERIC Educational Resources Information Center

Herman, Emilia; Stefanescu, Daniela

2017-01-01

This paper approaches the issue of higher entrepreneurship education in motivating young people to start their own business as a viable alternative to the successful integration of university graduates on the labour market. The fundamental question of this research is if, currently, entrepreneurship education influences students' entrepreneurial…

Physics First: Impact on SAT Math Scores

ERIC Educational Resources Information Center

Bouma, Craig E.

2013-01-01

Improving science, technology, engineering, and mathematics (STEM) education has become a national priority and the call to modernize secondary science has been heard. A Physics First (PF) program with the curriculum sequence of physics, chemistry, and biology (PCB) driven by inquiry- and project-based learning offers a viable alternative to the…

Walking the Talk: The Complexities of Teaching about Teaching

ERIC Educational Resources Information Center

Ball, Tamara; Wells, Gordon

2006-01-01

Teaching a course entitled "Introduction to Theories of Education" requires that one practice what one is preaching. We describe an attempt to organize and provide undergraduates enrolled in an introductory course of 300+ students, with a viable, yet more collaborative and "product-based" alternative to the familiar lecture and…

Advances in Brassica seed meal formulation for apple replant disease control

USDA-ARS?s Scientific Manuscript database

Brassicaceae seed meals when used independently do not provide uniform and sufficient control of the pathogen complex that incites apple replant disease for this soil amendment to be used as a viable alternative to pre-plant soil fumigation. Therefore, field trials were established at multiple site...

Agrobacterium-Mediated Transformation of Bread and Durum Wheat Using Freshly Isolated Immature Embryos

NASA Astrophysics Data System (ADS)

Huixia, Wu; Angela, Doherty; Jones, Huw D.

Agrobacterium-mediated transformation of wheat is becoming a viable alternative to the more established biolistic protocols. It offers advantages in terms of simple, low-copy-number integrations and can be applied with similar efficiencies to specific durum wheat and spring and winter bread wheat types varieties.

Effects of E-Textbook Instructor Annotations on Learner Performance

ERIC Educational Resources Information Center

Dennis, Alan R.; Abaci, Serdar; Morrone, Anastasia S.; Plaskoff, Joshua; McNamara, Kelly O.

2016-01-01

With additional features and increasing cost advantages, e-textbooks are becoming a viable alternative to paper textbooks. One important feature offered by enhanced e-textbooks (e-textbooks with interactive functionality) is the ability for instructors to annotate passages with additional insights. This paper describes a pilot study that examines…

Castration is no laughing matter, nitrous oxide can’t even help

USDA-ARS?s Scientific Manuscript database

Castration of pigs is necessary since no other viable alternative is yet available. However, castration is painful and analgesics are being considered to relieve pain. Inhalant gases with analgesic properties allow for a fast induction, short-term and reversible effects, and are a needle-free option...

The Infusion of Corporate Values into Progressive Education: Professional Vulnerability or Complicity?

ERIC Educational Resources Information Center

Gamson, David A.

2004-01-01

Examines the history of educational administration in the USA during the Progressive era (1890-1940). Using Callahan's Education and the Cult of Efficiency as a starting point, examines school district-based administrative practices that offered viable alternatives to the business-oriented, "scientific management" reforms that tended to…

Tapping the US historic sweet sorghum collection to identify biofuel germplasm

USDA-ARS?s Scientific Manuscript database

Sweet sorghum [Sorghum bicolor (L.) Moench] has gained an important role as a viable alternative to fossil fuels and a more profitable option than maize and sugarcane. Nevertheless, the actual narrow genetic base in sweet sorghum breeding programs is limiting the development of new biofuel varietie...

Running Rings Around the Web.

ERIC Educational Resources Information Center

McDermott, Irene E.

1999-01-01

Describes the development and current status of WebRing, a service that links related Web sites into a central hub. Discusses it as a viable alternative to other search engines and examines issues of free speech, use by the business sector, and implications for WebRing after its purchase by Yahoo! (LRW)

Ebook Approval Plans: Integration to Meet User Needs

ERIC Educational Resources Information Center

Buckley, Matthew; Tritt, Deborah

2011-01-01

Within academic library collections, electronic journals are a mainstay. Ebooks, on the other hand, have established themselves as a viable alternative to the print book more slowly. The growing acceptance and prevalence of ebooks cannot be ignored. As libraries continue to build their collections, ebooks play an increasingly larger role in…

Analyzing clonal fidelity of micropropagated Psidium guajava L. plants using simple sequence repeat markers

USDA-ARS?s Scientific Manuscript database

Micropropagation of Psidium guajava L. (guava) is a viable alternative to currently adopted techniques for large-scale plant propagation of commercial cultivars. Assessment of clonal fidelity in micropropagated plants is the first step towards ensuring genetic uniformity in mass production of planti...

Tax-exempt private placements: a new opportunity for not-for-profit providers.

PubMed

Ambrose, Jim; Harris, Andrew

2006-08-01

Tax-exempt private placements offer an attractive financing alternative for not-for-profit healthcare providers for which the public debt market is no longer a viable option. They offer the following advantages: Greater flexibility Lower fees. Less paperwork. Fewer players. Shorter time to complete.

Voluntary Childlessness: A Neglected Area of Family Study

ERIC Educational Resources Information Center

Veevers, J. E.

1973-01-01

Empirical research on childlessness would provide a necessary control group for analyses of motivations for parenthood, and of the effects of children on personal and marital adjustment. Knowledge of the conditions under which voluntary childlessness constitutes a viable and satisfactory alternate life style would have implications for more…

Cultural Assumptions against Sustainability: An International Survey

ERIC Educational Resources Information Center

Gambini, Barbara

2006-01-01

Despite the great progress in increasing public awareness of and attention to the issue of sustainability, the measures taken so far fall dramatically short of halting deleterious cycles. This apparent deficiency can be ascribed to two main factors: insufficient efforts to finding viable and visible alternatives and the failure to thoroughly…

Ultrasonic power transfer from a spherical acoustic wave source to a free-free piezoelectric receiver: Modeling and experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shahab, S.; Gray, M.; Erturk, A., E-mail: alper.erturk@me.gatech.edu

2015-03-14

Contactless powering of small electronic components has lately received growing attention for wireless applications in which battery replacement or tethered charging is undesired or simply impossible, and ambient energy harvesting is not a viable solution. As an alternative to well-studied methods of contactless energy transfer, such as the inductive coupling method, the use of ultrasonic waves transmitted and received by piezoelectric devices enables larger power transmission distances, which is critical especially for deep-implanted electronic devices. Moreover, energy transfer by means of acoustic waves is well suited in situations where no electromagnetic fields are allowed. The limited literature of ultrasonic acousticmore » energy transfer is mainly centered on proof-of-concept experiments demonstrating the feasibility of this method, lacking experimentally validated modeling efforts for the resulting multiphysics problem that couples the source and receiver dynamics with domain acoustics. In this work, we present fully coupled analytical, numerical, and experimental multiphysics investigations for ultrasonic acoustic energy transfer from a spherical wave source to a piezoelectric receiver bar that operates in the 33-mode of piezoelectricity. The fluid-loaded piezoelectric receiver under free-free mechanical boundary conditions is shunted to an electrical load for quantifying the electrical power output for a given acoustic source strength of the transmitter. The analytical acoustic-piezoelectric structure interaction modeling framework is validated experimentally, and the effects of system parameters are reported along with optimal electrical loading and frequency conditions of the receiver.« less

Atmospheric Modeling of Mars Methane Plumes

NASA Astrophysics Data System (ADS)

Mischna, Michael A.; Allen, M.; Lee, S.

2010-10-01

We present two complementary methods for isolating and modeling surface source releases of methane in the martian atmosphere. From recent observations, there is strong evidence that periodic releases of methane occur from discrete surface locations, although the exact location and mechanism of release is still unknown. Numerical model simulations with the Mars Weather Research and Forecasting (MarsWRF) general circulation model (GCM) have been applied to the ground-based observations of atmospheric methane by Mumma et al., (2009). MarsWRF simulations reproduce the natural behavior of trace gas plumes in the martian atmosphere, and reveal the development of the plume over time. These results provide constraints on the timing and location of release of the methane plume. Additional detections of methane have been accumulated by the Planetary Fourier Spectrometer (PFS) on board Mars Express. For orbital observations, which generally have higher frequency and resolution, an alternate approach to source isolation has been developed. Drawing from the concept of natural selection within biology, we apply an evolutionary computational model to this problem of isolating source locations. Using genetic algorithms that `reward’ best-fit matches between observations and GCM plume simulations (also from MarsWRF) over many generations, we find that we can potentially isolate source locations to within tens of km, which is within the roving capabilities of future Mars rovers. Together, these methods present viable numerical approaches to restricting the timing, duration and size of methane release events, and can be used for other trace gas plumes on Mars as well as elsewhere in the solar system.

Comparative analysis of solar pasteurization versus solar disinfection for the treatment of harvested rainwater.

PubMed

Strauss, André; Dobrowsky, Penelope Heather; Ndlovu, Thando; Reyneke, Brandon; Khan, Wesaal

2016-12-09

Numerous pathogens and opportunistic pathogens have been detected in harvested rainwater. Developing countries, in particular, require time- and cost-effective treatment strategies to improve the quality of this water source. The primary aim of the current study was thus to compare solar pasteurization (SOPAS; 70 to 79 °C; 80 to 89 °C; and ≥90 °C) to solar disinfection (SODIS; 6 and 8 hrs) for their efficiency in reducing the level of microbial contamination in harvested rainwater. The chemical quality (anions and cations) of the SOPAS and SODIS treated and untreated rainwater samples were also monitored. While the anion concentrations in all the samples were within drinking water guidelines, the concentrations of lead (Pb) and nickel (Ni) exceeded the guidelines in all the SOPAS samples. Additionally, the iron (Fe) concentrations in both the SODIS 6 and 8 hr samples were above the drinking water guidelines. A >99% reduction in Escherichia coli and heterotrophic bacteria counts was then obtained in the SOPAS and SODIS samples. Ethidium monoazide bromide quantitative polymerase chain reaction (EMA-qPCR) analysis revealed a 94.70% reduction in viable Legionella copy numbers in the SOPAS samples, while SODIS after 6 and 8 hrs yielded a 50.60% and 75.22% decrease, respectively. Similarly, a 99.61% reduction in viable Pseudomonas copy numbers was observed after SOPAS treatment, while SODIS after 6 and 8 hrs yielded a 47.27% and 58.31% decrease, respectively. While both the SOPAS and SODIS systems reduced the indicator counts to below the detection limit, EMA-qPCR analysis indicated that SOPAS treatment yielded a 2- and 3-log reduction in viable Legionella and Pseudomonas copy numbers, respectively. Additionally, SODIS after 8 hrs yielded a 2-log and 1-log reduction in Legionella and Pseudomonas copy numbers, respectively and could be considered as an alternative, cost-effective treatment method for harvested rainwater.

Life cycle analysis of switchgrass converted via pyrolysis, gasification, and fermentation

USDA-ARS?s Scientific Manuscript database

The US is promoting and developing low carbon fuel sources. Perennial bioenergy crops such as switchgrass (Panicum virgatum L.) are one viable source for low carbon transportation fuels. The objective is to determine the net greenhouse gas (GHG) emissions from different conversion methods (pyrolysi...

ENGINEERING STUDY FOR THE 200 AREA EFFLUENT TREATMENT FACILITY (ETF) SECONDARY WASTE TREATMENT OF PROJECTED FUTURE WASTE FEEDS

DOE Office of Scientific and Technical Information (OSTI.GOV)

LUECK, K.J.

2004-10-18

This report documents an engineering study conducted to evaluate alternatives for treating secondary waste in the secondary treatment train (STT) of the Hanford Site 200 Area Effluent Treatment Facility (ETF). The study evaluates ETF STT treatment alternatives and recommends preferred alternatives for meeting the projected future missions of the ETF. The preferred alternative(s) will process projected future ETF influents to produce a solid waste acceptable for final disposal on the Hanford Site. The main text of this report summarizes the ETF past and projected operations, lists the assumptions about projected operations that provide the basis for the engineering evaluation, andmore » summarizes the evaluation process. The evaluation process includes identification of available modifications to the current ETF process, screens those modifications for technical viability, evaluates the technically viable alternatives, and provides conclusions and recommendations based on that evaluation.« less

Viable Cancer Cells in the Remnant Stomach are a Potential Source of Peritoneal Metastasis after Curative Distal Gastrectomy for Gastric Cancer.

PubMed

Murata, Satoshi; Yamamoto, Hiroshi; Yamaguchi, Tsuyoshi; Kaida, Sachiko; Ishida, Mitsuaki; Kodama, Hirokazu; Takebayashi, Katsushi; Shimizu, Tomoharu; Miyake, Toru; Tani, Tohru; Kushima, Ryoji; Tani, Masaji

2016-09-01

The mechanisms underlying peritoneal metastasis (PM) after curative gastrectomy for gastric cancer (GC) are not well elucidated. This study assessed whether viable cancer cells, including cancer stemlike cells (CSCs), were present in the remnant stomach immediately before gastrointestinal (GI) tract reconstruction because these could be a source of PM after gastrectomy. Saline fluid used for remnant stomach lumen irrigation before GI reconstruction was prospectively collected from 142 consecutive patients undergoing distal gastrectomy for GC and cytologically examined. Proliferative activity (Ki67 staining) and stemness (expression of the CSC surface markers CD44s or CD44v6) were evaluated in detected cancer cells. Viable cancer cells were detected in 33 (23.2 %) of the 142 remnant stomachs. These cells formed clusters and stained positively for Ki67, indicating proliferation. Cancer cells in remnant stomachs and surface cancer cells in primary GCs from 10 (30.3 %) of these 33 cases also stained positively for CD44s or CD44v6. In a multiple logistic regression analysis, advanced cancer (odds ratio [OR], 4.65; 95 % confidence interval [CI], 1.32-16.4; P = 0.017), tumor size of 40 mm or larger (OR, 3.78; 95 % CI, 1.12-12.8; P = 0.033), and histologic differentiation (OR, 3.10; 95 % CI, 1.30-7.40; P = 0.011) were associated independently with the presence of cancer cells in the remnant stomach. Viable, proliferative, and clustered cancer cells, including CSCs, were found in remnant gastric lumens immediately before GI reconstruction, indicating a possible cellular source of PM after curative gastrectomy for GC. Dissemination of gastric contents into the peritoneal cavity should be avoided during GI reconstruction.

Using endometrial ablation as a treatment for abnormal bleeding: energy source comparisons and clinical results

NASA Astrophysics Data System (ADS)

Ryan, Thomas P.

2000-01-01

A great number of women suffer from abnormal uterine bleeding. Most do not want to undergo a hysterectomy and have searched for an alternative treatment. Ablation of the endometrium has become a viable alternative. Initially, surgical applications utilized thermal ablation by passing a rolling electrode, energized by monopolar radiofrequency (RF) energy, to ablate the inner uterine lining. This procedure was done under visual guidance and required practiced surgical skills to perform the ablation. It was not possible to assess subsurface damage. More recently, various energy systems have been applied to the endometrium such as lasers, microwaves, monopolar and bipolar RF, hot fluid balloons, and cryotherapy. They are being used in computer controlled treatments that obviate the user's skill, and utilize a self-positioning device paired with a temperature monitored, thermal treatment. Finite element models have also been created to predict heating profiles with devices that either rely on conductive heating or that deposit power in tissue. This is a very active field in terms of innovation with creative solutions using contemporary technology to reduce or halt the bleeding. Devices and minimally invasive treatments will offer choices to women and will be able to replace a surgical procedure with an office-based procedure. They are very promising and are discussed at length herein.

Plant parts substitution based approach as a viable conservation strategy for medicinal plants: A case study of Premna latifolia Roxb.

PubMed

Jena, Ashish Kumar; Karan, Maninder; Vasisht, Karan

Rapid population growth and catastrophic harvesting methods of wild medicinal plants especially trees, result in the exploitation of natural sources and its management is the need of the hour. Dashamoolarishta is an amalgam of roots of ten plants of a popular Ayurvedic FDC formulation consisting of the root of Premna latifolia Roxb. as one of its ingredients. Presently, their populations like many other trees are under threat due to extensive use of the roots by the herbal drug industry. With an aim to conserve the biodiversity, a systematic study based on a rational approach by substituting root/root bark with alternative and renewable parts was conducted. The fingerprint profile together with anti-inflammatory and analgesic effect of different parts of the plant was established for comparison. The results based on chemical and biological study indicated close similarity between the roots and the leaves and suggest the possible use of latter over root/root bark. The study proposes that the substitution of the root with alternate renewable parts of the same plant shall form the best strategy towards conservation of the trees like P. latifolia. Copyright © 2016 Transdisciplinary University, Bangalore and World Ayurveda Foundation. Published by Elsevier B.V. All rights reserved.

Metal–organic framework with optimally selective xenon adsorption and separation

DOE PAGES

Banerjee, Debasis; Simon, Cory M.; Plonka, Anna M.; ...

2016-06-13

Nuclear energy is considered among the most viable alternatives to our current fossil fuel based energy economy.1 The mass-deployment of nuclear energy as an emissions-free source requires the reprocessing of used nuclear fuel to mitigate the waste.2 One of the major concerns with reprocessing used nuclear fuel is the release of volatile radionuclides such as Xe and Kr. The most mature process for removing these radionuclides is energy- and capital-intensive cryogenic distillation. Alternatively, porous materials such as metal-organic frameworks (MOFs) have demonstrated the ability to selectively adsorb Xe and Kr at ambient conditions.3-8 High-throughput computational screening of large databases ofmore » porous materials has identified a calcium-based nanoporous MOF, SBMOF-1, as the most selective for Xe over Kr.9,10 Here, we affirm this prediction and report that SBMOF-1 exhibits by far the highest Xe adsorption capacity and a remarkable Xe/Kr selectivity under relevant nuclear reprocessing conditions. The exceptional selectivity of SBMOF-1 is attributed to its pore size tailored to Xe and its dense wall of atoms that constructs a binding site with a high affinity for Xe, as evident by single crystal X-ray diffraction and molecular simulation.« less

The intramolecular position of docosahexaenoic acid in the triacylglycerol sources used for pediatric nutrition has a minimal effect on its metabolic use.

PubMed

Sala-Vila, Aleix; Castellote, Ana I; López-Sabater, M Carmen

2008-03-01

Docosahexaenoic acid (DHA) plays an important role in normal development of the brain and retina in the human. In utero, DHA is incorporated in the fetus, and its accretion continues throughout early postnatal life. Although human breast milk contains this fatty acid, several organizations recommend supplementing infant formulas with DHA for infants and premature infants. Traditionally, certain types of fish oil have been used for fortifying some infant formulas, but with the decline in world fisheries, the search for alternative sources of DHA continues. Among the viable ingredient sources of DHA is oil derived from single-cell organisms (marine microorganisms); however, these oil sources display different positional specificity of DHA in the glycerol lipids compared with that found in human breast milk lipids. In the latter, the DHA is mainly esterified in the central position of the glycerol backbone. Because of these differences in human milk and oils derived from single-cell organisms, recent research in biotechnology has focused on developing new structured triacylglycerols with an intramolecular structure resembling that found in human milk lipids. This research is justified by the potential differences in metabolism of DHA based on the hypothetical bioavailability and benefits in DHA found in human milk lipids. Presented herein is a review of the published research on the metabolism of DHA from different triacylglycerol sources including in vitro studies and animal studies. Despite small differences observed in digestion, the current data reveal a minimal effect on the parameters of development studied for the intramolecular position in which DHA is esterified.

Multipole models of four-image gravitational lenses with anomalous flux ratios

NASA Astrophysics Data System (ADS)

Congdon, Arthur B.; Keeton, Charles R.

2005-12-01

It has been known for over a decade that many four-image gravitational lenses exhibit anomalous radio flux ratios. These anomalies can be explained by adding a clumpy cold dark matter (CDM) component to the background galactic potential of the lens. As an alternative, Evans & Witt (2003) recently suggested that smooth multipole perturbations provide a reasonable alternative to CDM substructure in some but not all cases. We generalize their method in two ways so as to determine whether multipole models can explain highly anomalous systems. We carry the multipole expansion to higher order, and also include external tidal shear as a free parameter. Fitting for the shear proves crucial to finding a physical (positive-definite density) model. For B1422+231, working to order kmax= 5 (and including shear) yields a model that is physical but implausible. Going to higher order (kmax>~ 9) reduces global departures from ellipticity, but at the cost of introducing small-scale wiggles in proximity to the bright images. These localized undulations are more pronounced in B2045+265, where kmax~ 17 multipoles are required to smooth out large-scale deviations from elliptical symmetry. Such modes surely cannot be taken at face value; they must indicate that the models are trying to reproduce some other sort of structure. Our formalism naturally finds models that fit the data exactly, but we use B0712+472 to show that measurement uncertainties have little effect on our results. Finally, we consider the system B1933+503, where two sources are lensed by the same foreground galaxy. The additional constraints provided by the images of the second source render the multipole model unphysical. We conclude that external shear must be taken into account to obtain plausible models, and that a purely smooth angular structure for the lens galaxy does not provide a viable alternative to the prevailing CDM clump hypothesis.

Bacteria in deep coastal plain sediments of Maryland: A possible source of CO2 to groundwater

NASA Astrophysics Data System (ADS)

Chapelle, Francis H.; Zelibor, Joseph L., Jr.; Grimes, D. Jay; Knobel, Leroy L.

1987-08-01

Nineteen cores of unconsolidated Coastal Plain sediments obtained from depths of 14 to 182 m below land surface near Waldorf, Maryland, were collected and examined for metabolically active bacteria. The age of the sediments cored range from Miocene to Early Cretaceous. Acridine orange direct counts of total (viable and nonviable) bacteria in core subsamples ranged from 108 to 104 bacteria/g of dry sediment. Direct counts of viable bacteria ranged from 106 to 103 bacteria/g of dry sediment. Three cores contained viable methanogenic bacteria, and seven cores contained viable sulfate-reducing bacteria. The observed presence of bacteria in these sediments suggest that heterotrophic bacterial metabolism, with lignitic organic material as the primary substrate, is a plausible source of CO2 to groundwater. However, the possibility that abiotic processes also produce CO2 cannot be ruled out. Estimated rates of CO2 production in the noncalcareous Magothy/Upper Patapsco and Lower Patapsco aquifers based on mass balance of dissolved inorganic carbon, groundwater flow rates, and flow path segment lengths are in the range 10-3 to 10-5 mmol L-1 yr-1. Isotope balance calculations suggest that aquifer-generated CO2 is much heavier isotopically (˜—10 to + 5 per mil) than lignite (˜-24 per mil) present in these sediments. This may reflect isotopic fractionation during methanogenesis and possibly other bacterially mediated processes.

MotorWeek

ScienceCinema

None

2017-12-27

In 2008, PBS's MotorWeek, television's original automotive magazine, visited Argonne's Transportation Technology R&D Center "To learn what it really takes to make clean power sources a viable reality."

New compact hohlraum configuration research at the 1.7 MA Z-pinch generator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kantsyrev, V. L., E-mail: victor@unr.edu; Shrestha, I. K.; Esaulov, A. A.

A new compact Z-pinch x-ray hohlraum design with parallel-driven x-ray sources was experimentally demonstrated in a full configuration with a central target and tailored shine shields (to provide a symmetric temperature distribution on the target) at the 1.7 MA Zebra generator. This presentation reports on the joint success of two independent lines of research. One of these was the development of new sources – planar wire arrays (PWAs). PWAs turned out to be a prolific radiator. Another success was the drastic improvement in energy efficiency of pulsed-power systems, such as the Load Current Multiplier (LCM). The Zebra/LCM generator almost doubledmore » the plasma load current to 1.7 MA. The two above-mentioned innovative approaches were used in combination to produce a new compact hohlraum design for ICF, as jointly proposed by SNL and UNR. Good agreement between simulated and measured radiation temperature of the central target is shown. Experimental comparison of PWAs with planar foil liners (PFL) - another viable alternative to wire array loads at multi-MA generators show promising data. Results of research at the University of Nevada Reno allowed for the study of hohlraum coupling physics at University-scale generators. The advantages of new hohlraum design applications for multi-MA facilities with W or Au double PWAs or PFL x-ray sources are discussed.« less

Marine Controlled Source EM Methods: Equipment, Methodology, and Results

NASA Astrophysics Data System (ADS)

Constable, S.; Behrens, J.; Key, K.

2005-12-01

The marine CSEM method has become an important tool for academia and the petroleum industry. Commercially viable seafloor receivers were developed for marine MT exploration over the last decade, but progress in CSEM transmitter design is still at an early stage. We have developed 200~A and 500~A transmitters (Scripps Undersea Electromagnetic Source Instrument, or SUESI-200/500) which operate within the 30~kVA power limitations of academic tow cables. This is done by careful control of antenna impedance (resistance and inductance) and power efficiency. Electrode impedance is largely a function of length, rather than surface area or diameter. The antenna can be made neutrally buoyant by balancing the weight of an aluminum conductor with a thick plastic jacket. Telemetry for control, navigation, and monitoring is overlaid on high voltage power transmission down coaxial tow cables, as an alternative to fiber optic telemetry, allowing use with winches and cables of opportunity. The CSEM noise floor determines the source--receiver ranges, and thus the investigation depths, that can be achieved, and depends on frequency, dipole moment, receiver noise, magnetotelluric interference, and stack time. For typical values, this is 10-15~VA-1m-2. We present examples of data from a sub-salt hydrocarbon prospect in the Gulf of Mexico, and an academic project over the magma chambers of the East Pacific Rise.

Characterization and pyrolysis of Chlorella vulgaris and Arthrospira platensis: potential of bio-oil and chemical production by Py-GC/MS analysis.

PubMed

Almeida, Hanna N; Calixto, Guilherme Q; Chagas, Bruna M E; Melo, Dulce M A; Resende, Fabio M; Melo, Marcus A F; Braga, Renata Martins

2017-06-01

Biofuels have been seen as potential sources to meet future energy demand as a renewable and sustainable energy source. Despite the fact that the production technology of first-generation biofuels is consolidated, these biofuels are produced from foods crops such as grains, sugar cane, and vegetable oils competing with food for crop use and agricultural land. In recent years, it was found that microalgae have the potential to provide a viable alternative to fossil fuels as source of biofuels without compromising food supplies or arable land. On this scenario, this paper aims to demonstrate the energetic potential to produce bio-oil and chemicals from microalgae Chlorella vulgaris and Arthrospira platensis. The potential of these biomasses was evaluated in terms of physical-chemical characterization, thermogravimetric analysis, and analytical pyrolysis interfaced with gas chromatograph (Py-GC/MS). The results show that C. vulgaris and A. platensis are biomasses with a high heating value (24.60 and 22.43 MJ/kg) and low ash content, showing a high percentage of volatile matter (72.49 and 79.42%). These characteristics confirm their energetic potential for conversion process through pyrolysis, whereby some important aromatic compounds such as toluene, styrene, and phenol were identified as pyrolysis products, which could turn these microalgae a potential for biofuels and bioproduct production through the pyrolysis.

Is self-sufficiency financially viable and ethically justifiable?--a commercial viewpoint.

PubMed

Christie, R B

1994-12-01

Manufacturers of blood products have to maintain the highest possible standards for plasma screening and good manufacturing practices to ensure maximum purity and viral safety. The private sector companies have much experience in implementing and complying with national and international regulations. These requirements involve considerable cost in the areas of (1) plasma collection facilities, (2) research and clinical research, (3) manufacture, and (4) quality control. Total self-sufficiency would mean the loss of many existing resources. An alternative would be a collaboration between the public and private sectors to meet the needs of all patients who require plasma derived products. The current definition of self-sufficiency suggests that it is not financially viable.

The Case for Open Source: Open Source Has Made Significant Leaps in Recent Years. What Does It Have to Offer Education?

ERIC Educational Resources Information Center

Guhlin, Miguel

2007-01-01

Open source has continued to evolve and in the past three years the development of a graphical user interface has made it increasingly accessible and viable for end users without special training. Open source relies to a great extent on the free software movement. In this context, the term free refers not to cost, but to the freedom users have to…

Analysis of the costs of fuel supply for wood-fired electric power plants in rural Liberia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perlack, R.D.; Barron, W.F.; Samuels, G.

1985-06-01

In recent years the quality of rural electric services in Liberia has been declining and the future economic viability of these power stations is a growing concern. Each of the ten operating and each of the planned rural public power stations is designed to operate exclusively on gas oil (diesel fuel). Fuel expenditures by the Liberian Electricity Corporation (LEC) for the rural public stations represent a major and growing burden on the financially hardpressed utility. Liberia has two potentially significant alternatives to oil-fired electric power for its up-country towns: small (1 to 5 MW) hydroelectric facilities, and wood-fired steam ormore » gasifier plants (0.2 to 2 MW). Although small hydroelectric facilities appear viable for several locations, they cannot serve all locations and will require thermal back-up. The economics of supplying wood to a rural electric power plant or rural grid were evaluated under several scenarios involving: (1) different sources of the feedstock, and (2) differences in wood supply requirements for plants based on the use of steam or gasifier technology, and variation in the utilization level for such plants. With a few minor exceptions, wood energy supplies are plentiful throughout Liberia. Liberia has four different potential sources of wood fuel supply: the commercial cutting of retired rubber trees; the harvesting of secondary growth forest just prior to the land returning to temporary cultivation as part of a system of shifting agriculture; adding to the system of shifting agriculture the planting of fast-growing wood species and harvesting these trees when the land again is brought back under cultivation (generally after about five to seven years); and the establishment of commercial short-rotation wood energy plantations. Results indicate that the use of wood to fuel rural power stations is a viable economic option.« less

Parametric evaluation of the cost effectiveness of Shuttle payload vibroacoustic test plans

NASA Technical Reports Server (NTRS)

Stahle, C. V.; Gongloff, H. R.; Keegan, W. B.; Young, J. P.

1978-01-01

Consideration is given to alternate vibroacoustic test plans for sortie and free flyer Shuttle payloads. Statistical decision models for nine test plans provide a viable method of evaluating the cost effectiveness of alternate vibroacoustic test plans and the associated test levels. The methodology is a major step toward the development of a useful tool for the quantitative tailoring of vibroacoustic test programs to sortie and free flyer payloads. A broader application of the methodology is now possible by the use of the OCTAVE computer code.

Laser power conversion system analysis, volume 2

NASA Technical Reports Server (NTRS)

Jones, W. S.; Morgan, L. L.; Forsyth, J. B.; Skratt, J. P.

1979-01-01

The orbit-to-ground laser power conversion system analysis investigated the feasibility and cost effectiveness of converting solar energy into laser energy in space, and transmitting the laser energy to earth for conversion to electrical energy. The analysis included space laser systems with electrical outputs on the ground ranging from 100 to 10,000 MW. The space laser power system was shown to be feasible and a viable alternate to the microwave solar power satellite. The narrow laser beam provides many options and alternatives not attainable with a microwave beam.

Fungal monitoring of the indoor air of the Museo de La Plata Herbarium, Argentina.

PubMed

Mallo, Andrea C; Elíades, Lorena A; Nitiu, Daniela S; Saparrat, Mario C N

Biological agents, such as fungal spores in the air in places where scientific collections are stored, can attack and deteriorate them. The aim of this study was to gather information on the indoor air quality of the Herbarium of Vascular Plants of the Museo de Ciencias Naturales de La Plata, Argentina, in relation to fungal propagules and inert particles. This study was made using a volumetric system and two complementary sampling methods: (1) a non-viable method for direct evaluation, and (2) a viable method by culture for viable fungal propagules. The non-viable method led to ten spore morphotypes being found from related fungal sources. A total of 4401.88spores/m 3 and 32135.18 inert suspended particles/m 3 were recorded. The viable method led to the finding of nine fungal taxa as viable spores that mostly belonged to anamorphic forms of Ascomycota, although the pigmented yeast Rhodotorula F.C. Harrison (Basidiomycota) was also found. A total count of 40,500fungal CFU/m 3 air was estimated for all the sites sampled. Both the non-viable and viable sampling methods were necessary to monitor the bio-aerosol load in the La Plata Herbarium. The indoor air of this institution seems to be reasonably adequate for the conservation of vascular plants due to the low indoor/outdoor index, low concentrations of air spores, and/or lack of indicators of moisture problems. Copyright © 2016 Asociación Española de Micología. Publicado por Elsevier España, S.L.U. All rights reserved.

The Most Economic, Socially Viable, and Environmentally Sustainable Alternative Energy

ERIC Educational Resources Information Center

Vanderburg, Willem H.

2008-01-01

The strengths and weaknesses of current energy planning can be attributed to the limited economic, social, and environmental contexts taken into account as a result of the current intellectual and professional division of labor. A preventive approach is developed by which the ratio of desired to undesired effects can be substantially improved. It…

A Short-Term, Intensive Workshop Approach for the Treatment of Human Sexual Inadequacy

ERIC Educational Resources Information Center

Blakeney, Patricia; And Others

1976-01-01

A rapid treatment approach to common sexual dysfunctions has been used in treating 59 couples, including 74 symptomatic individuals. The intensive workshop format resulted in a saving of patient and professional time and is seen as a viable alternative to more time-consuming approaches of treating various sexual dysfunctions. (Author)

MOLASSES AS THE PRIMARY ENERGY SUPPLEMENT ON AN ORGANIC GRAZING DAIRY FARM

USDA-ARS?s Scientific Manuscript database

Organic dairies in New York face challenges, including the high cost of purchasing organic feed grains. Many of these farms are looking for alternative ingredients to use that can be reasonably fed to lactating dairy cows, and that are less costly. Molasses seems to be a viable, less expensive, so...

Comparison as an Approach to the Experimental Method

ERIC Educational Resources Information Center

Turner, David A.

2017-01-01

In his proposal for comparative education, Marc Antoinne Jullien de Paris argues that the comparative method offers a viable alternative to the experimental method. In an experiment, the scientist can manipulate the variables in such a way that he or she can see any possible combination of variables at will. In comparative education, or in…

Podcasting 101 for K-12 Librarians

ERIC Educational Resources Information Center

Eash, Esther Kreider

2006-01-01

Podcast is a digital recording of a radio broadcast or similar program made available on the Internet for downloading to a personal audio player. In other words, it's a digital audio file that is created, shared, and heard. The podcast is a viable alternative for delivering research content or lessons to students who need remedial or extended…

A Review of Models for Computer-Based Testing. Research Report 2011-12

ERIC Educational Resources Information Center

Luecht, Richard M.; Sireci, Stephen G.

2011-01-01

Over the past four decades, there has been incremental growth in computer-based testing (CBT) as a viable alternative to paper-and-pencil testing. However, the transition to CBT is neither easy nor inexpensive. As Drasgow, Luecht, and Bennett (2006) noted, many design engineering, test development, operations/logistics, and psychometric changes…

Is Harm Reduction a Viable Choice for Kids Enchanted with Drugs?

ERIC Educational Resources Information Center

Laursen, Erik K.; Brasler, Paul

2002-01-01

This article describes a strengths-based alternative to substance abuse treatment. Many contemporary youth are experiencing problems with alcohol or other drugs but reject the message of total abstinence and disease models of treatment. The authors draw from their experience and research to combine a strengths perspective with a harm-reduction…

Analysis of parameter sensitivity and identifiability of root zone water quality model (RZWQM) for dryland sugerbeet modeling

USDA-ARS?s Scientific Manuscript database

Sugarbeet is being considered as one of the most viable feedstock alternatives to corn for biofuel production since herbicide resistant energy beets were deregulated by USDA in 2012. Growing sugarbeets for biofuel production may have significant impacts on soil health and water quality in the north-...

An Exploration of Egyptian Students' Attitudes toward Online Learning

ERIC Educational Resources Information Center

El-Zayaty, Nady

2018-01-01

Open and Distance Learning (ODL) has become an increasingly popular platform for delivering education the world over. The acceptance of ODL as a viable alternative to traditional brick and mortar educational institutes has been a topic of debate however. Furthermore, many questions have been raised about the different levels of interest…

NOVEL ASSAY TO ASSESS CYP-2E1-LIKE ACTIVITY IN THE JAPANESE MEDAKA (ORYZIAS LATIPES).

EPA Science Inventory

Liver microsomes and S-9 fraction of Japanese medaka (Oryzias latipes) metabolized the CYP2E1 specific substrate, p-nitrophenol (PNP), to a single hydroxylated product, 4-nitrocatechol. The use of liver S-9 fraction proved to be a viable alternative to liver microsomes and allowe...

Performance Ethnography: Creating a Mechanism for Engagement by the Academy.

ERIC Educational Resources Information Center

Jarmon, Leslie H.

Taking the position that performance ethnography should be a viable and valued alternative and/or supplement to print ethnography, this paper explores ways to integrate phenomena that are visual, aural, and dynamic into existing scholarly practices. The paper advances one solution: create mechanisms for reproduction and distribution that have the…

Effective Practices for Online Delivery of Quantitative Business Courses

ERIC Educational Resources Information Center

Lam, Helen; Khare, Anshuman

2010-01-01

Online delivery of university-level courses has grown exponentially in the last decade and is increasingly being recognised as a viable and effective alternative to face-to-face classroom teaching. Many scholars have already written about the benefits and best practices of online teaching in general. However, not many studies have paid specific…

A Text-Computer Assisted Instruction Program as a Viable Alternative for Continuing Education in Laboratory Medicine.

ERIC Educational Resources Information Center

Bruce, A. Wayne

1986-01-01

Describes reasons for developing combined text and computer assisted instruction (CAI) teaching programs for delivery of continuing education to laboratory professionals, and mechanisms used for developing a CAI program on method evaluation in the clinical laboratory. Results of an evaluation of the software's cost effectiveness and instructional…

A Primer on Logistic Regression.

ERIC Educational Resources Information Center

Woldbeck, Tanya

This paper introduces logistic regression as a viable alternative when the researcher is faced with variables that are not continuous. If one is to use simple regression, the dependent variable must be measured on a continuous scale. In the behavioral sciences, it may not always be appropriate or possible to have a measured dependent variable on a…

Introducing winter canola to the winter wheat-fallow region of the Pacific Northwest

USDA-ARS?s Scientific Manuscript database

Growers in the low-rainfall, winter wheat-fallow region of the Pacific Northwest are in need of an alternative crop to diversify their markets, manage pests, and increase wheat yields. Winter canola may be a viable crop option for growers in the region. However, agronomic research for winter canol...

Designing the Speech Communication Classroom: A Viable Alternative.

ERIC Educational Resources Information Center

Springhorn, Ron G.

This paper presents a structure for the speech communication classroom, based on a philosophically existential approach to education. The following suggestions are offered to those considering such an approach. There should be movable furniture, enabling students to move about and to turn toward one another so that they can be physically in…

Biofuel vs. Biodiversity? Integrated Emergy and Economic Cost-Benefit Evaluation of Rice-Ethanol Production in Japan

EPA Science Inventory

Energy analysis results confirmed that abandoned rice fields provide a good opportunity for Japan to fulfill its E-3 target by producing ethanol from high-yield rice feedstock. However, to be a viable alternative, a biofuel should not only provide a net energy gain and reduce the...

Microform Catalogs: A Viable Alternative for Texas Libraries.

ERIC Educational Resources Information Center

Cox, Carolyn, M.; Juergens, Bonnie

This project proposed to develop and test the use of microform catalogs produced from computer-generated magnetic tape records in both fiche and film formats. The Computer Output Microform (COM) catalog developed for this purpose is a union list of titles from the five participating libraries--Houston and Dallas Public Libraries, Texas State…

Reaching youth through franchise clinics: assessment of Kenyan private sector involvement in youth services.

PubMed

Decker, Martha; Montagu, Dominic

2007-03-01

This paper evaluates the ability of social franchise programs, which use private providers to offer reproductive health services, to provide services to youth in western Kenya. Although franchise clinics have rarely targeted youth, they appear to offer a viable alternative for providing reproductive health services to this age group.

Telepractice: The Australian Experience in an International Context

ERIC Educational Resources Information Center

McCarthy, Melissa; Duncan, Jill; Leigh, Greg

2012-01-01

Telepractice is emerging as a viable alternative to traditional "face-to-face" service as practitioners seek to meet the diverse needs of children who are deaf or hard of hearing and their families. Telepractice provides the opportunity for many countries to expand their reach and viability within their own borders as well as the…

Backtrack Programming: A Computer-Based Approach to Group Problem Solving.

ERIC Educational Resources Information Center

Scott, Michael D.; Bodaken, Edward M.

Backtrack problem-solving appears to be a viable alternative to current problem-solving methodologies. It appears to have considerable heuristic potential as a conceptual and operational framework for small group communication research, as well as functional utility for the student group in the small group class or the management team in the…

The Origin and Significance of the CCAM Line: Evidence from Chondrules and Dark Inclusions in Allende (CV3)

NASA Technical Reports Server (NTRS)

Greenwood, R. C.; Franchi, I. A.; Zolensky, M. E.; Buchanan, P. C.

2016-01-01

The process responsible for the mass independent oxygen isotope variation observed in Solar System materials remains poorly understood. While self-shielding of CO, either in the early solar nebula, or precursor molecular cloud, appears to be a viable mechanism, alternative models have also been proposed.

Careers and Couples: An Academic Question.

ERIC Educational Resources Information Center

Hoffmann, Leonore, Ed.; DeSole, Gloria, Ed.

The 20 articles in this collection concern issues faced by couples in academe. One group of articles considers part-time careers, independent scholarly work, or intermittent employment, which may be viable alternatives for women with families or those who feel less need for a full-time job. The need for institutional policies to support part-time…

Soil disturbance assessment of a cable logging operation performing five silvicultural prescriptions

Treesearch

John Klepac; Steve Reutebuch

2003-01-01

Evaluating alternative methods for regenerating second-growth Douglas-fir (Pseudotsuga menziesii) forests in the Pacific Northwest is an area of interest for resource managers. To meet future demands for timber supply as well as provide stands that are visually acceptable by the public and ecologically viable, a thorough understanding of these...

Managing conflict over biological control: the case of strawberry guava in Hawaii

Treesearch

Tracy Johnson

2016-01-01

Biological control researchers commonly avoid targets with potential for high conflict, but for certain highly damaging invaders with no viable management alternatives, it may be necessary to consider biological control even when it is likely to generate conflict. Discussed here is a case study, strawberry guava (Psidium cattleianum Sabine...

Derivation of sorting programs

NASA Technical Reports Server (NTRS)

Varghese, Joseph; Loganantharaj, Rasiah

1990-01-01

Program synthesis for critical applications has become a viable alternative to program verification. Nested resolution and its extension are used to synthesize a set of sorting programs from their first order logic specifications. A set of sorting programs, such as, naive sort, merge sort, and insertion sort, were successfully synthesized starting from the same set of specifications.

Strengths, Opportunities, Aspirations, and Results: An Emerging Approach to Organization Development

ERIC Educational Resources Information Center

Zarestky, Jill; Cole, Catherine S.

2017-01-01

Organization development (OD) interventions have typically relied on the strengths, weaknesses, opportunities, and threats (SWOT) framework for strategic planning. The strengths, opportunities, aspirations, and results (SOAR) framework is a relatively new innovation in OD that may serve as a viable alternative to SWOT for those who wish to apply…

The Economics of Concern and Compassion: Applications to Rural Justice.

ERIC Educational Resources Information Center

Brown, David W.

The urgent need to correct inequities and shortsighted rural justice practices, i.e., juvenile delinquency problems, makes it crucial that available resources be used wisely and that careful choices be made among the viable alternatives. Twelve basic economic concepts can be helpful in providing a framework or diagnostic perspective that can be…

Soybean Oil: Powering a High School Investigation of Biodiesel

ERIC Educational Resources Information Center

De La Rosa, Paul; Azurin, Katherine A.; Page, Michael F. Z.

2014-01-01

This laboratory investigation challenges students to synthesize, analyze, and compare viable alternative fuels to Diesel No. 2 using a renewable resource, as well as readily available reagents and supplies. During the experiment, students synthesized biodiesel from soybean oil in an average percent yield of 83.8 ± 6.3%. They then prepared fuel…

Cross-Validation of a Short Form of the Marlowe-Crowne Social Desirability Scale.

ERIC Educational Resources Information Center

Zook, Avery, II; Sipps, Gary J.

1985-01-01

Presents a cross-validation of Reynolds' short form of the Marlowe-Crowne Social Desirability Scale (N=233). Researchers administered 13 items as a separate entity, calculated Cronbach's Alpha for each sex, and computed test-retest correlation for one group. Concluded that the short form is a viable alternative. (Author/NRB)

A Recommendation for Managing the Predicted Growth in College Enrollment at a Time of Adverse Economic Conditions.

ERIC Educational Resources Information Center

Jones, Randolph

2003-01-01

Explores the option of using distance education courses as a viable alternative to building classrooms and facilities. Distance education could be one solution to the financial and physical facilities problems universities may have in dealing with the predicted economic and enrollment conditions. (AEF)

Poultry litter application to loblolly pine forests: growth and nutrient containment

Treesearch

Alexander L. Friend; Scott D. Roberts; Stephen H. Schoenholtz; Juanita A. Mobley; Patrick D. Gerard

2006-01-01

Forestland application of poultry manure offers an alternative to the conventional practice of pastureland application. Before such a practice is considered viable, however, it must be demonstrated that the forest ecosystem is capable of absorbing the nutrients contained in poultry manure, especially nitrogen (N) and phosphorus (P). From the forestry perspective, it...

Peer Mentoring--Is a Virtual Form of Support a Viable Alternative?

ERIC Educational Resources Information Center

Smailes, Joanne; Gannon-Leary, Pat

2011-01-01

Support systems are vital for university entrants and one established means of support is peer mentoring, which has the potential to improve student engagement and retention. Peer mentoring models are generally based on face-to-face contact. However, given the increasing number of higher education institutions using social media, might online…

Does Performance-Based Pay Improve Teaching? PISA in Focus. No. 16

ERIC Educational Resources Information Center

OECD Publishing (NJ1), 2012

2012-01-01

The Programme for International Student Assessment (PISA) has long established that high-performing education systems tend to pay their teachers more. They also often prioritise the quality of teaching over other choices, including class size. But in the current budgetary climate, paying everybody more may not be a viable alternative. So many…

Use of Social Welfare Programs and the Disintegration of the Black Nuclear Family.

ERIC Educational Resources Information Center

Jewell, K. Sue

1984-01-01

Social welfare programs contribute to Black women's decisions to terminate their marriages by modifying existing beliefs and values, giving rise to a perception of welfare as a more viable alternative to marital relationships. But welfare is insufficient to enable the maintenance of Black women's preseparation standard of living. (RDN)

Comparing Vignette Instruction and Assessment Tasks to Classroom Observations and Reflections

ERIC Educational Resources Information Center

Jeffries, Carolyn; Maeder, Dale W.

2011-01-01

The growing body of research on the use of vignettes in teacher education courses suggests that vignette-based instruction and assessment tasks may represent a viable alternative to traditional forms of scaffolded instruction and reflective essays following classroom observations, thereby creating a bridge between college and K-12 classrooms for…

Flow Injection Analysis and Liquid Chromatography for Multifunctional Chemical Analysis (MCA) Systems

ERIC Educational Resources Information Center

Mayo, Ana V.; Loegel, Thomas N.; Bretz, Stacey Lowery; Danielson, Neil D.

2013-01-01

The large class sizes of first-year chemistry labs makes it challenging to provide students with hands-on access to instrumentation because the number of students typically far exceeds the number of research-grade instruments available to collect data. Multifunctional chemical analysis (MCA) systems provide a viable alternative for large-scale…

Effects of alternative outcome scenarios and structured outcome evaluation on case-based ethics instruction.

PubMed

Peacock, Juandre; Harkrider, Lauren N; Bagdasarov, Zhanna; Connelly, Shane; Johnson, James F; Thiel, Chase E; Macdougall, Alexandra E; Mumford, Michael D; Devenport, Lynn D

2013-09-01

Case-based instruction has been regarded by many as a viable alternative to traditional lecture-based education and training. However, little is known about how case-based training techniques impact training effectiveness. This study examined the effects of two such techniques: (a) presentation of alternative outcome scenarios to a case, and (b) conducting a structured outcome evaluation. Consistent with the hypotheses, results indicate that presentation of alternative outcome scenarios reduced knowledge acquisition, reduced sensemaking and ethical decision-making strategy use, and reduced decision ethicality. Conducting a structured outcome evaluation had no impact on these outcomes. Results indicate that those who use case-based instruction should take care to use clear, less complex cases with only a singular outcome if they are seeking these types of outcomes.

Subcutaneous insulin therapy - end of the road after 80 years?

PubMed

Leifke, E; Strack, T R

2014-02-01

Subcutaneous (SC) insulin therapy has been a mainstay of pharmacological diabetes management from the moment insulin was successfully developed as treatment. Insulin formulations have become more refined and less allergenic over time, and ancillary technologies such as injection devices and glucose measurement tools have evolved to the extent of permitting closed-loop therapy. However, investigations have continued exploring alternative routes of administration with the ultimate goal of implantable islet replacements, whether cell- or "silicon"-based. Progress on these lines of research, however, has been slow to present patients with viable options: alternative delivery routes have failed to deliver insulin reliably and with commercially viable efficiency, while beta cell transplantation continues to struggle with tissue availability and in vivo viability. In the meantime, SC insulin formulations have advanced for rapid- and long-acting formulations, to better meet typical insulin requirements across the day. Thus, SC insulin will likely remain a key technology for the foreseeable future in order to address the needs of an ever larger number of insulin-dependent patients with diabetes. Copyright 2014 Prous Science, S.A.U. or its licensors. All rights reserved.

An overview of natural antimicrobials role in food.

PubMed

Pisoschi, Aurelia Magdalena; Pop, Aneta; Georgescu, Cecilia; Turcuş, Violeta; Olah, Neli Kinga; Mathe, Endre

2018-01-01

The present paper aims to review the natural food preservatives with antimicrobial properties emphasizing their importance for the future of food manufacturing and consumers' health. The extraction procedures applied to natural antimicrobials will be considered, followed by the description of some natural preservatives' antimicrobial mechanism of action, including (i) membrane rupture with ATP-ase activity inhibition, (ii) leakage of essential biomolecules from the cell, (iii) disruption of the proton motive force and (iiii) enzyme inactivation. Moreover, a provenance-based classification of natural antimicrobials is discussed by considering the sources of origin for the major natural preservative categories: plants, animals, microbes and fungi. As well, the structure influence on the antimicrobial potential is considered. Natural preservatives could also constitute a viable alternative to address the critical problem of microbial resistance, and to hamper the negative side effects of some synthetic compounds, while meeting the requirements for food safety, and exerting no negative impact on nutritional and sensory attributes of foodstuffs. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Modeling the Capacitive Deionization Process in Dual-Porosity Electrodes

DOE PAGES

Gabitto, Jorge; Tsouris, Costas

2016-04-28

In many areas of the world, there is a need to increase water availability. Capacitive deionization (CDI) is an electrochemical water treatment process that can be a viable alternative for treating water and for saving energy. A model is presented to simulate the CDI process in heterogeneous porous media comprising two different pore sizes. It is based on a theory for capacitive charging by ideally polarizable porous electrodes without Faradaic reactions or specific adsorption of ions. A two steps volume averaging technique is used to derive the averaged transport equations in the limit of thin electrical double layers. A one-equationmore » model based on the principle of local equilibrium is derived. The constraints determining the range of application of the one-equation model are presented. The effective transport parameters for isotropic porous media are calculated solving the corresponding closure problems. The source terms that appear in the average equations are calculated using theoretical derivations. The global diffusivity is calculated by solving the closure problem.« less

ePix100 camera: Use and applications at LCLS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carini, G. A., E-mail: carini@slac.stanford.edu; Alonso-Mori, R.; Blaj, G.

2016-07-27

The ePix100 x-ray camera is a new system designed and built at SLAC for experiments at the Linac Coherent Light Source (LCLS). The camera is the first member of a family of detectors built around a single hardware and software platform, supporting a variety of front-end chips. With a readout speed of 120 Hz, matching the LCLS repetition rate, a noise lower than 80 e-rms and pixels of 50 µm × 50 µm, this camera offers a viable alternative to fast readout, direct conversion, scientific CCDs in imaging mode. The detector, designed for applications such as X-ray Photon Correlation Spectroscopymore » (XPCS) and wavelength dispersive X-ray Emission Spectroscopy (XES) in the energy range from 2 to 10 keV and above, comprises up to 0.5 Mpixels in a very compact form factor. In this paper, we report the performance of the camera during its first use at LCLS.« less

Aiding Design of Wave Energy Converters via Computational Simulations

NASA Astrophysics Data System (ADS)

Jebeli Aqdam, Hejar; Ahmadi, Babak; Raessi, Mehdi; Tootkaboni, Mazdak

2015-11-01

With the increasing interest in renewable energy sources, wave energy converters will continue to gain attention as a viable alternative to current electricity production methods. It is therefore crucial to develop computational tools for the design and analysis of wave energy converters. A successful design requires balance between the design performance and cost. Here an analytical solution is used for the approximate analysis of interactions between a flap-type wave energy converter (WEC) and waves. The method is verified using other flow solvers and experimental test cases. Then the model is used in conjunction with a powerful heuristic optimization engine, Charged System Search (CSS) to explore the WEC design space. CSS is inspired by charged particles behavior. It searches the design space by considering candidate answers as charged particles and moving them based on the Coulomb's laws of electrostatics and Newton's laws of motion to find the global optimum. Finally the impacts of changes in different design parameters on the power takeout of the superior WEC designs are investigated. National Science Foundation, CBET-1236462.

Carbon recovery by fermentation of CO-rich off gases - Turning steel mills into biorefineries.

PubMed

Molitor, Bastian; Richter, Hanno; Martin, Michael E; Jensen, Rasmus O; Juminaga, Alex; Mihalcea, Christophe; Angenent, Largus T

2016-09-01

Technological solutions to reduce greenhouse gas (GHG) emissions from anthropogenic sources are required. Heavy industrial processes, such as steel making, contribute considerably to GHG emissions. Fermentation of carbon monoxide (CO)-rich off gases with wild-type acetogenic bacteria can be used to produce ethanol, acetate, and 2,3-butanediol, thereby, reducing the carbon footprint of heavy industries. Here, the processes for the production of ethanol from CO-rich off gases are discussed and a perspective on further routes towards an integrated biorefinery at a steel mill is given. Recent achievements in genetic engineering as well as integration of other biotechnology platforms to increase the product portfolio are summarized. Already, yields have been increased and the portfolio of products broadened. To develop a commercially viable process, however, the extraction from dilute product streams is a critical step and alternatives to distillation are discussed. Finally, another critical step is waste(water) treatment with the possibility to recover resources. Copyright © 2016 Elsevier Ltd. All rights reserved.

Extracts of the unripe fruit of Ilex paraguariensis as a potential chemical control against the golden apple snail Pomacea canaliculata (Gastropoda, Ampullariidae).

PubMed

Brito, Fabiano Carvalho de; Gosmann, Grace; Oliveira, Guendalina Turcato

2018-02-22

Plant extracts can provide a viable alternative to controlling many crop pests. This study sought to assess the efficacy of vegetable extracts of the unripe fruits of Ilex paraguariensis (yerba maté) for chemical control of the channeled apple snail (Pomacea canaliculata) and of non-target species as the South American catfish (Rhamdia quelen) under laboratory conditions. In P. canaliculata, the LC 50 of the decoction extract was 31.39 mg.L -1 and the LT 50 was over 26 h. The LC 50 of the butanol extract was 24.75 mg.L -1 and the LT 50 was in the range of 28 to 32 h. In juvenile R. quelen, the LC 50 of the decoction was 17.98 mg.L -1 and the LT 50 was in the range of 10-12 h. These extracts are particularly attractive considering the source of compounds and their effectiveness as molluscicides.

Fuel gain exceeding unity in an inertially confined fusion implosion.

PubMed

Hurricane, O A; Callahan, D A; Casey, D T; Celliers, P M; Cerjan, C; Dewald, E L; Dittrich, T R; Döppner, T; Hinkel, D E; Berzak Hopkins, L F; Kline, J L; Le Pape, S; Ma, T; MacPhee, A G; Milovich, J L; Pak, A; Park, H-S; Patel, P K; Remington, B A; Salmonson, J D; Springer, P T; Tommasini, R

2014-02-20

Ignition is needed to make fusion energy a viable alternative energy source, but has yet to be achieved. A key step on the way to ignition is to have the energy generated through fusion reactions in an inertially confined fusion plasma exceed the amount of energy deposited into the deuterium-tritium fusion fuel and hotspot during the implosion process, resulting in a fuel gain greater than unity. Here we report the achievement of fusion fuel gains exceeding unity on the US National Ignition Facility using a 'high-foot' implosion method, which is a manipulation of the laser pulse shape in a way that reduces instability in the implosion. These experiments show an order-of-magnitude improvement in yield performance over past deuterium-tritium implosion experiments. We also see a significant contribution to the yield from α-particle self-heating and evidence for the 'bootstrapping' required to accelerate the deuterium-tritium fusion burn to eventually 'run away' and ignite.

Re-reading nursing and re-writing practice: towards an empirically based reformulation of the nursing mandate.

PubMed

Allen, Davina

2004-12-01

This article examines field studies of nursing work published in the English language between 1993 and 2003 as the first step towards an empirically based reformulation of the nursing mandate. A decade of ethnographic research reveals that, contrary to contemporary theories which promote an image of nursing work centred on individualised unmediated caring relationships, in real-life practice the core nursing contribution is that of the healthcare mediator. Eight bundles of activity that comprise this intermediary role are described utilising evidence from the literature. The mismatch between nursing's culture and ideals and the structure and constraints of the work setting is a chronic source of practitioner dissatisfaction. It is argued that the profession has little to gain by pursuing an agenda of holistic patient care centred on emotional intimacy and that an alternative occupational mandate focused on the healthcare mediator function might make for more humane health services and a more viable professional future.

Feasibility of Ultraviolet Light Emitting Diodes as an Alternative Light Source for Photocatalysis

NASA Technical Reports Server (NTRS)

Levine, Langanf H.; Richards, Jeffrey T.; Soler, Robert; Maxik, Fred; Coutts, Janelle; Wheeler, Raymond M.

2011-01-01

The objective of this study was to determine whether ultraviolet light emitting diodes (UV-LEDs) could serve as an alternative photon source efficiently for heterogeneous photocatalytic oxidation (PCO). An LED module consisting of 12 high-power UV-A LEDs was designed to be interchangeable with a UV-A fluorescent black light blue (BLB) lamp in a Silica-Titania Composite (STC) packed bed annular reactor. Lighting and thermal properties were characterized to assess the uniformity and total irradiant output. A forward current of (I(sub F)) 100 mA delivered an average irradiance of 4.0 m W cm(exp -2), which is equivalent to the maximum output of the BLB, but the irradiance of the LED module was less uniform than that of the BLB. The LED- and BLB-reactors were tested for the oxidization of 50 ppmv ethanol in a continuous flow-through mode with 0.94 sec space time. At the same irradiance, the UV-A LED reactor resulted in a lower PCO rate constant than the UV-A BLB reactor (19.8 vs. 28.6 nM CO2 sec-I), and consequently lower ethanol removal (80% vs. 91%) and mineralization efficiency (28% vs. 44%). Ethanol mineralization increased in direct proportion to the irradiance at the catalyst surface. This result suggests that reduced ethanol mineralization in the LED- reactor could be traced to uneven irradiance over the photocatalyst, leaving a portion of the catalyst was under-irradiated. The potential of UV-A LEDs may be fully realized by optimizing the light distribution over the catalyst and utilizing their instantaneous "on" and "off' feature for periodic irradiation. Nevertheless, the current UV-A LED module had the same wall plug efficiency (WPE) of 13% as that of the UV-A BLB. These results demonstrated that UV-A LEDs are a viable photon source both in terms of WPE and PCO efficiency.

Specific detection of viable Listeria monocytogenes in Spanish wastewater treatment plants by Fluorescent In Situ Hybridization and PCR.

PubMed

Moreno, Yolanda; Ballesteros, Lorena; García-Hernández, Jorge; Santiago, Paula; González, Ana; Ferrús, M Antonia

2011-10-01

Listeria monocytogenes detection in wastewater can be difficult because of the large amount of background microbiota and the presence of viable but non-culturable forms in this environment. The aim of this study was to evaluate a Fluorescent In Situ Hybridization (FISH) assay combined with Direct Viable Count (DVC) method for detecting viable L. monocytogenes in wastewater samples, as an alternative to conventional culture methods. 16S rRNA sequence data were used to design a specific oligonucleotide probe. In order to assess the suitability of the method, the assays were performed on naturally (n=87) and artificially (n=14) contaminated samples and results were compared to those obtained with the isolation of cells on selective media and with a PCR method. The detection limit of FISH and PCR assays was 10(4) cells/mL without enrichment and 10 cells/mL after enrichment. A total of 47 samples, including 3 samples from effluent sites, yielded FISH positive results for L. monocytogenes. Using DVC-FISH technique, the presence of viable L. monocytogenes cells was detected in 23 out of these 47 FISH positive wastewater samples. PCR and culture methods yielded 27 and 23 positive results, respectively. According to these results, FISH technique has the potential to be used as a sensitive method for the detection and enumeration of L. monocytogenes in environmental wastewater samples. Copyright © 2011 Elsevier Ltd. All rights reserved.

Kinetics of killing Listeria monocytogenes by macrophages: correlation of /sup 3/H-DNA release from labeled bacteria and changes in numbers of viable organisms by mathematical model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davies, W.A.

1982-12-01

Conventional methods of assessing antibacterial activities of macrophages by viable counting are limited by the precision of the statistics and are difficult to interpret quantitatively because of unrestrained extracellular growth of bacteria. An alternative technique based on the release of radioactive DNA from labeled bacteria has been offered as overcoming these drawbacks. To assess it for use with macrophages I have made a correlation with the conventional viable counting method using a mathematical model. Opsonized Listeria monocytogenes labeled with /sup 3/H-thymidine were exposed to rat macrophages for periods up to 4 hr. Numbers of viable bacteria determined after sonication increasedmore » exponentially in the absence of live cells and this growth rate was progressively inhibited by increasing numbers of macrophages. After a lag period of 30-60 min soluble /sup 3/H appeared in the supernatant, the amount increasing with time and numbers of macrophages. To correlate these data I developed a mathematical model that considered that changes in numbers of viable organisms were due to the difference between rates of 1) growth of extracellular bacteria and 2) killing within the macrophage. On the basis of this model curves of best fit to the viable counts data were used to predict the release of radioactivity, assuming that death of a bacterium led to the total release of its label. These predictions and the experimental data agreed well, the lag period of 30-60 min between death of the bacterium and release of radioactivity being consistent with intracellular digestion. Release of soluble radioactivity appears to be an accurate reflection of the number of bacteria killed within the macrophage.« less

Immunization against chlamydial genital infection in guinea pigs with UV-inactivated and viable chlamydiae administered by different routes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rank, R.G.; Batteiger, B.E.; Soderberg, L.S.

1990-08-01

Female guinea pigs were immunized with viable or UV light-inactivated chlamydiae, belonging to the species Chlamydia psittaci, by intravenous, subcutaneous, oral, or ocular routes. All animals were then inoculated vaginally with viable chlamydiae to determine the extent of protection against challenge infection induced by the various regimens. The course of genital infection was significantly reduced in intensity in all groups of animals except the unimmunized controls and those animals immunized orally with inactivated antigen. Guinea pigs immunized with viable antigen were more likely to develop resistance to challenge infection and, in general, had a significantly greater degree of protection thanmore » animals immunized with inactivated antigen. No one route seemed superior in producing a protective response. Animals in all groups demonstrating protection developed serum and secretion immunoglobulin G antibody responses to chlamydiae. Lymphocyte proliferative reactions to chlamydial antigen were variable among groups. Immunoblot analysis of serum and secretions indicated a wide range of antibody specificities, but most protected animals produced antibodies to the major outer membrane protein, lipopolysaccharide, and the 61-kilodalton protein. No definitive associations could be made between the increased ability of immunization with viable organisms to produce resistance to challenge infection and a particular immune parameter. These data indicate that viable chlamydiae given by various routes are able to induce a strong immune response which can provide resistance against reinfection in some cases or at least reduce the degree of infection to a greater degree than inactivated antigen. However, complete resistance to genital tract infection may be difficult to obtain and alternate immunizations strategies may have to be developed.« less

Microalgae Feedstocks for Aviation Fuels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wigmosta, Mark S.; Coleman, Andre; Venteris, Erik

There is significant global interest in developing, testing, and using alternative jet fuels for both commercial and military use in an effort to create a sustainable and stable fuel supply while reducing greenhouse gas emissions. Currently, the aviation industry is entirely dependent on a finite-supply of petroleum based fuel sourced in part by politically and economically unstable regions of the world. Commercial jet fuel use within the contiguous United States (CONUS) was 17.8 billion gallons per year (BGY) in 2009, while jet fuel use in 2010 by the U.S. Air Force (USAF), Navy, and Army was 1.5 BGY, 0.6 BGY,more » and 0.8 BGY, respectively (Carter et al., 2011). U.S. commercial and military aviation sectors have set ambitious near-term alternative fuel and environmental performance targets. This includes a tentative Federal Aviation Administration (FAA) goal of 1 BGY alternative fuel use by commercial aircraft by 2018. The USAF has set a target of 50% for USAF domestic aviation via alternative fuels by 2016 (0.73 BGY), and 50% of the Navy’s total energy consumption afloat (0.3 BGY) will come from alternative fuels by 2020 (Carter et al., 2011). If these targets become policy, at least 2 BGY of domestically-produced alternative jet fuel will be required by 2020. The Energy Independence and Security Act (EISA) of 2007 established production requirements for domestic alternative fuels under the Renewable Fuel Standard (RFS). For example, 36 billion gallons of renewable fuel must be produced by 2022, of which 21 billion gallons shall be advanced biofuels. EISA defines advanced biofuels as non-corn starch derived biofuels having lifecycle greenhouse gas emissions 50% lower than gasoline. There a number of potential fuel pathways for meeting the RFS. One of these is biomass-based diesel, including jet fuel (Schnepf and Yacobucci, 2013). The U.S. Department of Energy (DOE) Bioenergy Technologies Office (BETO) has a stated goal in its 2013 Multi-Year Program Plan (USDOE, 2013) to support the RFS through development of “…commercially viable biomass utilization technologies to encourage the creation of a new domestic bioenergy industry…”. BETO has also recognized the potential for aviation biofuels to support the bioenergy industry, seeing drop-in bio-based jet fuels one of the viable alternatives for the aviation industry and the military to meet their ambitious near-term GHG reduction targets (USDOE, 2014). One of the important Multi-year Program Plan Targets (USDOE, 2013) is to establish feedstock resource assessment models to evaluate the geographic, economic, quality and environmental criteria for which 20 million metric tons of ash free dry weight (AFDW) algal biomass can be produced by 2022. Toward meeting the EISA requirements, algal biofuels may offer a number of advantages. They can produce a range of biofuel feedstocks suitable for diesel and aviation fuels. Microalgae, on a strain-specific basis, can be cultivated using impaired water including saline, and/or brackish pumped groundwater or seawater, treated industrial wastewater, municipal sewage effluent, and produced water generated from oil and gas drilling operations. Additionally, microalgae require nitrogen and phosphates as essential nutrients and could provide water treatment co-benefits to municipalities, industry, and the environment.« less

Goat oocyte quality and competence to undergo IVM and embryo development after parthenogenetic activation from goats fed with different levels of cashew nut bran as source of dietary lipids.

PubMed

Fernandes, C C L; Feltrin, C; Martins, L T; Gaudêncio Neto, S; Aguiar, L H; Silva, A M; Oliveira, C H A; Silva, L M; Silva, C M G; Bertolini, M; Rondina, D

2014-07-15

Lipid-rich and energy-dense diets can have significant effects on the reproductive physiology, including the ovarian function and fertility. The aim of this study was to assess the effect of cashew nut bran supplementation as a lipid source on follicle development, plasma and intrafollicular concentrations of cholesterol, and developmental competence of in vitro-matured goat oocytes. The inclusion of cashew nut bran as 24% of the goats' diet for 28 days increased the percentage and number of degenerated oocytes compared with the control (P < 0.05), and also the plasma cholesterol levels and the proportion of grade IV oocytes compared with all other treatments (P < 0.05). Moreover, a significant reduction was observed in the proportion of viable oocytes compared with the control and in the percentage of grade II oocytes compared with all other treatments (P < 0.05). Oocyte maturation, cleavage, and blastocyst rates after parthenogenetic activation of viable oocytes were not affected by the type of diet. In conclusion, the inclusion of cashew nut bran as 24% of the diet of adult goats for 28 days changed plasma cholesterol levels and reduced the proportion of viable immature oocytes; however, the 12% and 24% diet supplementations with cashew nut bran did not interfere with competence of resulting viable oocytes to reach the metaphase II stage after IVM, and to develop after parthenogenetic activation. Copyright © 2014 Elsevier Inc. All rights reserved.

An analysis of producing ethanol and electric power from woody residues and agricultural crops in East Texas

NASA Astrophysics Data System (ADS)

Ismayilova, Rubaba Mammad

The increasing U.S. dependence on imported oil; the contribution of fossil fuels to the greenhouse gas emissions and the climate change issue; the current level of energy prices and other environmental concerns have increased world interest in renewable energy sources. Biomass is a large, diverse, readily exploitable resource. This dissertation examines the biomass potential in Eastern Texas by examining a 44 county region. This examination considers the potential establishment of a 100-megawatt (MW) power plant and a 20 million gallon per year (MMGY) ethanol plant using lignocellulosic biomass. The biomass sources considered are switchgrass, sugarcane bagasse, and logging residues. In the case of electricity generation, co-firing scenarios are also investigated. The research analyzes the key indicators involved with economic costs and benefits, environmental and social impacts. The bioenergy production possibilities considered here were biofeedstock supported electric power and cellulosic ethanol production. The results were integrated into a comprehensive set of information that addresses the effects of biomass energy development in the region. The analysis indicates that none of the counties in East Texas have sufficient biomass to individually sustain either a 100% biomass fired power plant or the cellulosic ethanol plant. Such plants would only be feasible at the regional level. Co-firing biomass with coal, however, does provide a most attractive alternative for the study region. The results indicate further that basing the decision solely on economics of feedstock availability and costs would suggest that bioenergy, as a renewable energy, is not a viable energy alternative. Accounting for some environmental and social benefits accruing to the region from bioenergy production together with the feedstock economics, however, suggests that government subsidies, up to the amount of accruing benefits, could make the bioenergies an attractive business opportunity for local farmers and investors.

SnO2, IrO2, Ta2O5, Bi2O3, and TiO2 nanoparticle anodes: electrochemical oxidation coupled with the cathodic reduction of water to yield molecular H2

NASA Astrophysics Data System (ADS)

Choi, Jina; Qu, Yan; Hoffmann, Michael R.

2012-08-01

In recent years, the search for environmentally friendly alternative energy sources with reduced carbon footprints has increased. The coupling of photovoltaic power sources with advanced electrolysis systems for hydrogen production via water splitting using organic contaminants as sacrificial electron donors has been considered to a be viable alternative. In this report, we demonstrated the feasibility of a scaled-up rooftop prototype of the proposed hybrid photovoltaic-electrolysis system, which utilizes semiconductor nanoparticles coated on to metal substrates as electrodes for the generation of hydrogen coupled with the oxidation of wastewater. Application of an anodic bias of >2.0 V to bismuth-doped TiO2 (BiO x -TiO2) on Ti metal anodes with a sequential under-coatings of nanoparticulate SnO2, IrO2, Ta2O5, and Bi2O3 results in the electrochemical degradation of a variety of organic chemical contaminants in water (i.e., rhodamine B (Rh.B), methylene blue (MB), salicylic acid, triclosan, and phenol) and actual wastewater from a chemical manufacturing plant, while at the same time, molecular hydrogen is produced at stainless steel (SS) cathodes. The kinetics of the anodic substrates oxidation is investigated as a function of the cell current ( I cell), substrate concentration, and background electrolyte composition (e.g., NaCl, Na2SO4, or seawater). Average current efficiencies were found to be in the range of 4-22 %, while the cathodic current and energy efficiencies for hydrogen production were found to be in the range of 50-70 % and 20-40 %, respectively.

49 CFR 7.46 - Alternative sources of information.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Alternative sources of information. 7.46 Section 7... § 7.46 Alternative sources of information. In the interest of making documents of general interest publicly available at as low a cost as possible, alternative sources will be arranged whenever possible. In...

Preservation of Rhizobium viability and symbiotic infectivity by suspension in water

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crist, D.K.; Wyza, R.E.; Mills, K.K.

1984-05-01

Three Rhizobium japonicum strains and two slow-growing cowpea-type Rhizobium strains were found to remain viable and able to rapidly nodulate their respective hosts after being stored in purified water at ambient temperatures for periods of 1 year and longer. Three fast-growing Rhizobium species did not remain viable under the same water storage conditions. After dilution of slow-growing Rhizobium strains with water to 10/sup 3/ to 10/sup 5/ cells ml/sup -1/, the bacteria multiplied until the viable cell count reached levels of between 10/sub 6/ and 10/sup 7/ cells ml/sup -1/. The viable cell count subsequently remained fairly constant. When themore » rhizobia were diluted to 10/sup 7/ cells ml/sup -1/, they did not multiply, but full viability was maintained. If the rhizobia were washed and suspended at 10/sup 9/ cells ml/sup -1/, viability slowly declined to 10/sup 7/ cells ml/sup -1/ during 9 months of storage. Scanning electron microscopy showed that no major morphological changes took place during storage. Preservation of slow-growing rhizobia in water suspensions could provide a simple and inexpensive alternative to current methods for the preservation of rhizobia for legume inoculation. 25 references, 7 figures, 2 tables.« less

Ancient Glass: A Literature Search and its Role in Waste Management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Strachan, Denis M.; Pierce, Eric M.

2010-07-01

When developing a performance assessment model for the long-term disposal of immobilized low-activity waste (ILAW) glass, it is desirable to determine the durability of glass forms over very long periods of time. However, testing is limited to short time spans, so experiments are performed under conditions that accelerate the key geochemical processes that control weathering. Verification that models currently being used can reliably calculate the long term behavior ILAW glass is a key component of the overall PA strategy. Therefore, Pacific Northwest National Laboratory was contracted by Washington River Protection Solutions, LLC to evaluate alternative strategies that can be usedmore » for PA source term model validation. One viable alternative strategy is the use of independent experimental data from archaeological studies of ancient or natural glass contained in the literature. These results represent a potential independent experiment that date back to approximately 3600 years ago or 1600 before the current era (bce) in the case of ancient glass and 106 years or older in the case of natural glass. The results of this literature review suggest that additional experimental data may be needed before the result from archaeological studies can be used as a tool for model validation of glass weathering and more specifically disposal facility performance. This is largely because none of the existing data set contains all of the information required to conduct PA source term calculations. For example, in many cases the sediments surrounding the glass was not collected and analyzed; therefore having the data required to compare computer simulations of concentration flux is not possible. This type of information is important to understanding the element release profile from the glass to the surrounding environment and provides a metric that can be used to calibrate source term models. Although useful, the available literature sources do not contain the required information needed to simulate the long-term performance of nuclear waste glasses in a near-surface or deep geologic repositories. The information that will be required include 1) experimental measurements to quantify the model parameters, 2) detailed analyses of altered glass samples, and 3) detailed analyses of the sediment surrounding the ancient glass samples.« less

Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications.

PubMed

Moraghebi, Roksana; Kirkeby, Agnete; Chaves, Patricia; Rönn, Roger E; Sitnicka, Ewa; Parmar, Malin; Larsson, Marcus; Herbst, Andreas; Woods, Niels-Bjarne

2017-08-25

Mesenchymal stromal cells (MSCs) are currently being evaluated in numerous pre-clinical and clinical cell-based therapy studies. Furthermore, there is an increasing interest in exploring alternative uses of these cells in disease modelling, pharmaceutical screening, and regenerative medicine by applying reprogramming technologies. However, the limited availability of MSCs from various sources restricts their use. Term amniotic fluid has been proposed as an alternative source of MSCs. Previously, only low volumes of term fluid and its cellular constituents have been collected, and current knowledge of the MSCs derived from this fluid is limited. In this study, we collected amniotic fluid at term using a novel collection system and evaluated amniotic fluid MSC content and their characteristics, including their feasibility to undergo cellular reprogramming. Amniotic fluid was collected at term caesarean section deliveries using a closed catheter-based system. Following fluid processing, amniotic fluid was assessed for cellularity, MSC frequency, in-vitro proliferation, surface phenotype, differentiation, and gene expression characteristics. Cells were also reprogrammed to the pluripotent stem cell state and differentiated towards neural and haematopoietic lineages. The average volume of term amniotic fluid collected was approximately 0.4 litres per donor, containing an average of 7 million viable mononuclear cells per litre, and a CFU-F content of 15 per 100,000 MNCs. Expanded CFU-F cultures showed similar surface phenotype, differentiation potential, and gene expression characteristics to MSCs isolated from traditional sources, and showed extensive expansion potential and rapid doubling times. Given the high proliferation rates of these neonatal source cells, we assessed them in a reprogramming application, where the derived induced pluripotent stem cells showed multigerm layer lineage differentiation potential. The potentially large donor base from caesarean section deliveries, the high yield of term amniotic fluid MSCs obtainable, the properties of the MSCs identified, and the suitability of the cells to be reprogrammed into the pluripotent state demonstrated these cells to be a promising and plentiful resource for further evaluation in bio-banking, cell therapy, disease modelling, and regenerative medicine applications.

Elevating Learner Achievement Using Formative Electronic Lab Assessments in the Engineering Laboratory: A Viable Alternative to Weekly Lab Reports

ERIC Educational Resources Information Center

Chen, Baiyun; DeMara, Ronald F.; Salehi, Soheil; Hartshorne, Richard

2018-01-01

A laboratory pedagogy interweaving weekly student portfolios with onsite formative electronic laboratory assessments (ELAs) is developed and assessed within the laboratory component of a required core course of the electrical and computer engineering (ECE) undergraduate curriculum. The approach acts to promote student outcomes, and neutralize…

Distance Learning as a Viable Staff Development Alternative for Behavioral Healthcare Direct Support Professionals

ERIC Educational Resources Information Center

Gill, James G., Jr.

2011-01-01

This quasi-experiment utilized three groups of direct service staff to explore the effectiveness of three methods of training and an optional survey was offered after the study. The researcher used a counterbalance design. Three courses developed by an independent distance learning company were utilized to provide the learning experience. Each…

Articulating Scientific Practice: Understanding Dean Hamer's "Gay Gene" Study as Overlapping Material, Social and Rhetorical Registers

ERIC Educational Resources Information Center

Lynch, John A.

2009-01-01

Rhetoricians have tried to develop a better understanding of the connection between words and things, but these attempts often employ a logic of representation that undermines a full examination of materiality and the complexity of scientific practice. A logic of articulation offers a viable alternative by focusing attention on the linkages…

Techno-economic analysis of guayule (parthenium argentatum) pyrolysis biorefining: production of biofuels from guayule bagasse via tail-gas reactive pyrolysis

USDA-ARS?s Scientific Manuscript database

The tire industry is currently considering natural rubber from guayule (Parthenium argentatum Gray) as a viable alternative to imported Hevea natural rubber, or petroleum-based synthetics, to meet expanding materials needs of the industry, however, only 5-10% of the harvested guayule plant is conver...

Dual Mode Offering as Viable Approach for Promotion of Higher Education in Pakistan

ERIC Educational Resources Information Center

Hussain, Irshad

2014-01-01

Pakistan is a developing country with 148 universities and degree awarding institutions including public and private sector. The enrolment as given in the National Educational Policy 2009 was up to 5% only. It reflects greater demands of higher/tertiary education and calls for alternative strategic measures for addressing the issue. An innovative…

Practice-Based Evidence: Intelligent Action Inquiry for Complex Problems

ERIC Educational Resources Information Center

Eppley, Karen; Shannon, Patrick

2017-01-01

We have two goals for this article: to question the efficacy of evidence-based practice as the foundation of reading education policy and to propose practice-based evidence as a viable, more socially just alternative. In order to reach these goals, we describe the limits of reading policies of the last half century and argue for the possibilities…

Missing the target: DNAk is a dominant epitope in the humoral immune response of channel catfish (Ictalurus punctatus) to Flavobacterium columnare

USDA-ARS?s Scientific Manuscript database

Vaccination remains a viable alternative for bacterial disease protection in fish; however additional work is required to understand the mechanisms of adaptive immunity in the channel catfish. To assess the humoral immune response to Flavobacterium columnare; a group of channel catfish were first im...

Koranic Education Centres: A Viable Educational Alternative for the Disadvantaged Learner in Sahel Africa?

ERIC Educational Resources Information Center

Bah-Lalya, Ibrahima

2015-01-01

Within the international momentum for achieving Education for All (EFA) and the Millennium Development Goals (MDGs), many African countries have made considerable progress during the last decade in terms of access to basic education. However, a significant number of children enrolled in the early grades of primary schools either repeat classes or…

Diagnosis of AIDS-Related Intestinal Parasites

DTIC Science & Technology

1989-01-20

other intestinal parasites: Giardia lamblia (65), Endolimax nana (35), Entamoeba coli (33), Chilomastix mesnili (25), Ascaris lumbricoides (8...likely at risk for infection. ELISA Testing for Entamoeba histolytica, Giardia lamblia, Cryptosporidium 7. Taylor DN, Houston R, Shlim DR, Echeverria P...Assn 260:1245-1248, 1988. Significance: ELISA testing for Entamoeba histolytica antigen in fecal specimens is a viable alternative to traditional

Vegetarianism. New Horizons in Nutrition.

ERIC Educational Resources Information Center

Arnold, Justine; Grogan, Jane, Ed.

This instructional handbook is one of a series of ten packets designed to form a comprehensive course in nutrition for secondary students. This unit examines the vegetarian diet as a viable alternative, and at the same time, it introduces the topics of protein and vitamin B12. It contains a page of teaching suggestions, a pre-test for the…

Direct seeding of shortleaf pine

Treesearch

Corinne S. Mann; David Gwaze

2007-01-01

Direct seeding is a potentially viable method for regenerating shortleaf pine, but it has not been used extensively. In Missouri, an estimated 10,000 acres have been direct-seeded with shortleaf pine; half of which are at Mark Twain National Forest. Direct seeding offers a flexible and efficient alternative to planting as a way to restore shortleaf pine in the Ozarks....

Overall aspects of Bt in forest service cooperative gypsy moth suppression projects

Treesearch

Noel F. Schneeberger

1985-01-01

Improvements in Bt performance and cost, coupled with public concerns over human health risks have elevated Bt to a viable alternative to chemical insecticides. Operational use of Bt in recent years has demonstrated that while foliage protection can generally be achieved in most situations, gypsy moth population reduction cannot. Efforts are needed to improve Bt...

43 CFR 404.44 - What criteria will Reclamation apply to determine whether it is appropriate to recommend that a...

Code of Federal Regulations, 2012 CFR

2012-10-01

... waters, non-potable waters, and water-reuse-based water supplies; (2) Has a positive effect on public and... THE INTERIOR RECLAMATION RURAL WATER SUPPLY PROGRAM Appraisal Investigations § 404.44 What criteria... in the investigation, whether the alternative: (1) Identifies viable water supplies and water rights...

43 CFR 404.44 - What criteria will Reclamation apply to determine whether it is appropriate to recommend that a...

Code of Federal Regulations, 2013 CFR

2013-10-01

... waters, non-potable waters, and water-reuse-based water supplies; (2) Has a positive effect on public and... THE INTERIOR RECLAMATION RURAL WATER SUPPLY PROGRAM Appraisal Investigations § 404.44 What criteria... in the investigation, whether the alternative: (1) Identifies viable water supplies and water rights...

43 CFR 404.44 - What criteria will Reclamation apply to determine whether it is appropriate to recommend that a...

Code of Federal Regulations, 2014 CFR

2014-10-01

... waters, non-potable waters, and water-reuse-based water supplies; (2) Has a positive effect on public and... THE INTERIOR RECLAMATION RURAL WATER SUPPLY PROGRAM Appraisal Investigations § 404.44 What criteria... in the investigation, whether the alternative: (1) Identifies viable water supplies and water rights...

Microbial survey of a full-scale, biologically active filter for treatment of drinking water.

PubMed

White, Colin P; Debry, Ronald W; Lytle, Darren A

2012-09-01

The microbial community of a full-scale, biologically active drinking water filter was surveyed using molecular techniques. Nitrosomonas, Nitrospira, Sphingomonadales, and Rhizobiales dominated the clone libraries. The results elucidate the microbial ecology of biological filters and demonstrate that biological treatment of drinking water should be considered a viable alternative to physicochemical methods.

Peer Supervision for the Professional Development of School Counselors: Toward an Understanding of Terms and Findings

ERIC Educational Resources Information Center

Wilkerson, Kevin

2006-01-01

Current literature indicates a discrepancy between school counselors' reported desires for clinical supervision and their actual participation. To bridge this gap, peer supervision has been suggested as a viable alternative. However, a lack of definitional clarity makes it difficult to distinguish this activity from both clinical supervision and…

Development of polyion-complex hydrogels as an alternative approach for the production of bio-based polymers for food packaging applications: A review

USDA-ARS?s Scientific Manuscript database

Development of packaging materials from renewable resources has for a long time been desirable for sustainability reasons, but with the recent explosion in prices of petroleum products, this now becomes also more economically viable. This paper shows how fundamental chemistry underlying three forms ...

The Blended Learning Environment: A Viable Alternative for Special Needs Students

ERIC Educational Resources Information Center

Rivera, Jennifer Hall

2017-01-01

The traditional classroom provides a classical medium for educating students by allowing an open forum of communication between the pupil and teacher. The last twenty-five years have opened a new realm of possibilities in education through the use of technology and virtual supplemental resources, designed to engage learners in all academic levels.…

The Group Setting: A Viable Mental Health Alternative for the Elderly.

ERIC Educational Resources Information Center

Klinger-Vartabedian, Laurel C.

Group settings offer the elderly a unique outlet for interpersonal communication and can alleviate social isolation and aloneness. Group cohesiveness and instillation of hope are two curative factors in the group setting. Persons working with the elderly must be aware of their special problems and also be sensitive to their own age bias. Group…

A Case Study of the Efficacy of Middle College on Educational Advancement

ERIC Educational Resources Information Center

Wilson, Piper

2015-01-01

The purpose of the study was to examine the role of a middle college as a viable educational alternative to the traditional school environment and as one that supported student transition from high school into post-secondary education. Middle college is a unique transitional program in which students can participate in high school and college…

RNA-Based Methods Increase the Detection of Fecal Bacteria and Fecal Identifiers in Environmental Waters

EPA Science Inventory

We evaluated the use of qPCR RNA-based methods in the detection of fecal bacteria in environmental waters. We showed that RNA methods can increase the detection of fecal bacteria in multiple water matrices. The data suggest that this is a viable alternative for the detection of a...

Communities of Practice: A Research Paradigm for the Mixed Methods Approach

ERIC Educational Resources Information Center

Denscombe, Martyn

2008-01-01

The mixed methods approach has emerged as a "third paradigm" for social research. It has developed a platform of ideas and practices that are credible and distinctive and that mark the approach out as a viable alternative to quantitative and qualitative paradigms. However, there are also a number of variations and inconsistencies within the mixed…

The Prairie Valley Project: Reactions to a Transition to a Schoolwide, Multiage Elementary Classroom Design

ERIC Educational Resources Information Center

Bailey, Gregory J.; Werth, Eric P.; Allen, Donna M.; Sutherland, Leonie L.

2016-01-01

Originating from progressive educators who saw the need for student-centered educational designs rather than the traditional, single-age classroom design based on Henry Ford's assembly line, the multiage classroom design is returning as a viable alternative to the single-age classroom. The authors explored the perceptions of parents and teachers…

Structuring Assignments to Improve Understanding and Presentation Skills: Experiential Learning in the Capstone Strategic Management Team Presentation

ERIC Educational Resources Information Center

Helms, Marilyn M.; Whitesell, Melissa

2017-01-01

In the strategic management course, students select, analyze, and present viable future alternatives based on information provided in cases or computer simulations. Rather than understanding the entire process, the student's focus is on the final presentation. Chickering's (1977) research on active learning suggests students learn more effectively…

The effects of feeding monensin on rumen microbial communities and methanogenesis in bred heifers fed in a drylot

USDA-ARS?s Scientific Manuscript database

Drylot beef cow-calf systems are viable alternative management systems to traditional forage-based systems. In such confinement, adding ionophores such as monensin to the diets of beef cattle is common, and has been shown to improve feed efficiency and increase average daily gain. The addition of mo...

The Online University Classroom: One Perspective for Effective Student Engagement and Teaching in an Online Environment

ERIC Educational Resources Information Center

Carr, Marsha

2014-01-01

Universities struggle with alternate means of instructional delivery to meet the demands of distant student needs, the competition for enrollments, and restraints from limited physical building space. For many, fully online programs of study using internet-based instruction commonly named online instruction have become viable solutions. There has…

Comparing Food Label Experiments Using Samples from Web Panels versus Mall Intercepts

ERIC Educational Resources Information Center

Chang, LinChiat; Lin, Chung-Tung Jordan

2015-01-01

To regulate health messages on food labels, the U.S. Food and Drug Administration (FDA) traditionally relied on mall intercepts to collect consumer data. In recent years, web surveys have presented a viable alternative for presenting visual stimuli with more control and efficiency in data collection. However, there is a paucity of empirical data…

Jerusalem artichoke (Helianthus tuberosus, L.) maintains high inulin, tuber yield, and antioxidant capacity under moderately-saline irrigation waters

USDA-ARS?s Scientific Manuscript database

The scarcity of good quality water in semiarid regions of the world is the main limiting factor for increased irrigated agriculture in those regions. Saline water is generally widely available in arid regions at reduced costs, and can be a viable alternative for crop irrigation. However, the literat...

Introduction to the Special Section: Toward a Dimensionally Based Taxonomy of Psychopathology

PubMed Central

Krueger, Robert F.; Watson, David; Barlow, David H.

2008-01-01

Much current psychopathology research is framed by categorical constructs. Limitations of categorical constructs have been articulated, and dimensional constructs are often proposed as viable alternatives to categories of psychopathology. The purpose of this Special Section is to articulate and discuss diverse issues that arise in contemplating dimensional constructs as targets for psychopathology research. PMID:16351372

Environmentally Based Assessment Practices: Viable Alternatives to Standardized Assessment for Assessing Emergent Literacy Skills in Young Children

ERIC Educational Resources Information Center

Thurman, S. Kenneth; McGrath, Marie C.

2008-01-01

Ecological validity is an important construct in the assessment of young children. The argument is made that using environmentally based assessment practices as well as understanding the child's ecology will help assure that assessments are carried out in an ecologically valid manner. The discussion focuses on play-based assessment,…

Advantages of Gardening as a Form of Physical Activity in an After-School Program

ERIC Educational Resources Information Center

Phelps, Joshua; Hermann, Janice R.; Parker, Stephany P.; Denney, Barbara

2010-01-01

Children who normally abstain from physical activity may view gardening as a viable non-competitive alternative. The study reported here evaluated the effect of an Oklahoma Cooperative Extension Service after-school gardening program on self-reported physical activity level of children in 3rd through 5th grade using the ACTIVITY self-report…

Postoptimality analysis in the selection of technology portfolios

NASA Technical Reports Server (NTRS)

Adumitroaie, Virgil; Shelton, Kacie; Elfes, Alberto; Weisbin, Charles R.

2006-01-01

This paper describes an approach for qualifying optimal technology portfolios obtained with a multi-attribute decision support system. The goal is twofold: to gauge the degree of confidence in the optimal solution and to provide the decision-maker with an array of viable selection alternatives, which take into account input uncertainties and possibly satisfy non-technical constraints.

An assessment of the productivity for meat and the carcass yield of camels (Camelus dromedarius) and of the consumption of camel meat in the eastern region of Ethiopia.

PubMed

Kurtu, M Y

2004-01-01

A survey on camel meat productivity and consumption was conducted in Jijiga and Harar towns in 1999. Almost all the camels slaughtered were adults, predominantly males. Measurements of height, hump girth and thoracic girth were used to estimate the live weight. All the measurements were significantly greater in the male than in the female camels. Average live and carcass weights were 400 and 211 kg, respectively. Males were significantly heavier (p < 0.05) and had better dressing percentages than females. The carcasses contained averages of 76% meat, 12% fat and 20% bone for both males and females. The difference between the males and females was not significant for the ratio of meat and bones, except for fat, which was higher in the males. Camel meat is regarded as a high-quality food with medicinal value and as a least-cost source of meat. Camel meat is preferred to that of any other livestock by some people, particularly by the Somalis in Jijiga town. It is also more available, especially during the dry season when beef is in short supply. Hence, camel meat is a socially acceptable, economically viable and environmentally adaptable alternative source of meat, consumption of which should be encouraged.

Regeneration alternatives for upland white spruce after burning and logging in interior Alaska

USGS Publications Warehouse

Densmore, R.V.; Juday, G.P.; Zasada, J.C.

1999-01-01

Site-preparation and regeneration methods for white spruce (Picea glauca (Moench) Voss) were tested near Fairbanks, Alaska, on two upland sites which had been burned in a wildfire and salvage logged. After 5 and 10 years, white spruce regeneration did not differ among the four scarification methods but tended to be lower without scarification. Survival of container-grown planted seedlings stabilized after 3 years at 93% with scarification and at 76% without scarification. Broadcast seeding was also successful, with one or more seedlings on 80% of the scarified 6-m2 subplots and on 60% of the unscarified subplots after 12 years. Natural regeneration after 12 years exceeded expectations, with seedlings on 50% of the 6-m2 subplots 150 m from a seed source and on 28% of the subplots 230 m from a seed source. After 5 years, 37% of the scarified unsheltered seed spots and 52% of the scarified seed spots with cone shelters had one or more seedlings, but only 16% of the unscarified seed spots had seedlings, with and without funnel shelters. Growth rates for all seedlings were higher than on similar unburned sites. The results show positive effects of burning in interior Alaska, and suggest planting seedlings, broadcast seeding, and natural seedfall, alone or in combination, as viable options for similar sites.

ON ULTRA-HIGH-ENERGY COSMIC RAYS AND THEIR RESULTANT GAMMA-RAYS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gavish, Eyal; Eichler, David

2016-05-01

The Fermi Large Area Telescope collaboration has recently reported on 50 months of measurements of the isotropic extragalactic gamma-ray background (EGRB) spectrum between 100 MeV and 820 GeV. Ultra-high-energy cosmic ray (UHECR) protons interact with the cosmic microwave background photons and produce cascade photons of energies 10 MeV–1 TeV that contribute to the EGRB flux. We examine seven possible evolution models for UHECRs and find that UHECR sources that evolve as the star formation rate (SFR), medium low luminosity active galactic nuclei type-1 ( L = 10{sup 43.5} erg s{sup −1} in the [0.5–2] KeV band), and BL Lacertae objectsmore » (BL Lacs) are the most acceptable given the constraints imposed by the observed EGRB. Other possibilities produce too much secondary γ -radiation. In all cases, the decaying dark matter (DM) contribution improves the fit at high energy, but the contribution of still unresolved blazars, which would leave the smallest role for decaying DM, may yet provide an alternative improvement. The possibility that the entire EGRB can be fitted with resolvable but not-yet-resolved blazars, as recently claimed by Ajello et al., would leave little room in the EGRB to accommodate γ -rays from extragalactic UHECR production, even for many source evolution rates that would otherwise be acceptable. We find that under the assumption of UHECRs being mostly protons, there is not enough room for producing extragalactic UHECRs with active galactic nucleus, gamma-ray burst, or even SFR source evolution. Sources that evolve as BL Lacs, on the other hand, would produce much less secondary γ -radiation and would remain a viable source of UHECRs, provided that they dominate.« less

Estimating and validating surface energy fluxes at field scale over a heterogeneous land surfaces based on two-source energy balance model (TSEB)

USDA-ARS?s Scientific Manuscript database

Accurate estimation of surface energy fluxes at field scale over large areas has the potential to improve agricultural water management in arid and semiarid watersheds. Remote sensing may be the only viable approach for mapping fluxes over heterogeneous landscapes. The Two-Source Energy Balance mode...

48 CFR 206.202 - Establishing or maintaining alternative sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Open Competition After Exclusion of Sources 206.202 Establishing or maintaining alternative sources. (a) Agencies may use this authority to totally or partially exclude a particular source from a contract action... maintaining alternative sources. 206.202 Section 206.202 Federal Acquisition Regulations System DEFENSE...

Rapid detox: understanding new treatment approaches for the addicted patient.

PubMed

McCabe, S

2000-01-01

Despite substantive advances in understanding of genetic and biochemical basis of substance abuse and addiction in the last decade, little information has been translated into alternative treatment models for the addicted patient. Rapid detox, an alternative form of detox treatment, is gaining in both acceptance and popularity. To increase readers' understanding of the neurobiology of addiction and the mode of action of new detox approaches for patients addicted to opiate drugs. A review of the current literature pertaining to rapid detox. Rapid detox is a viable alternative for selected patients attempting to detox from opiate agents of abuse. Increasing knowledge of new treatment approaches allows nurses working to assist addicted patients in planning and receiving treatment based on new awareness of the neurobiology of addiction.

Shallow, non-pumped wells: a low-energy alternative for cleaning polluted groundwater.

PubMed

Hudak, Paul F

2013-07-01

This modeling study evaluated the capability of non-pumped wells with filter media for preventing contaminant plumes from migrating offsite. Linear configurations of non-pumped wells were compared to permeable reactive barriers in simulated shallow homogeneous and heterogeneous aquifers. While permeable reactive barriers enabled faster contaminant removal and shorter distances of contaminant travel, non-pumped wells also prevented offsite contaminant migration. Overall, results of this study suggest that discontinuous, linear configurations of non-pumped wells may be a viable alternative to much more costly permeable reactive barriers for preventing offsite contaminant travel in some shallow aquifers.

Aileron controls for wind turbine applications

NASA Technical Reports Server (NTRS)

Miller, D. R.; Putoff, R. L.

1984-01-01

Horizontal axis wind turbines which utilize partial or full variable blade pitch to regulate rotor speed were examined. The weight and costs of these systems indicated a need for alternate methods of rotor control. Aileron control is an alternative which has potential to meet this need. Aileron control rotors were tested on the Mod-O wind turbine to determine their power regulation and shutdown characteristics. Test results for a 20 and 38% chord aileron control rotor are presented. Test is shown that aileron control is a viable method for safety for safely controlling rotor speed, following a loss of general load.

Phytoestrogens: a viable option?

PubMed

Russell, Lori; Hicks, G Swink; Low, Annette K; Shepherd, Jinna M; Brown, C Andrew

2002-10-01

Estrogen replacement therapy is one of the most commonly prescribed medicines in the United States by traditional medical professionals. Over the past decade, the market for complementary/ alternative therapies for hormone replacement has dramatically increased. Women are seeking more "natural" alternatives to treat menopausal symptoms. Well-designed randomized clinical trials are often lacking, as is the information on efficacy and safety. This article will review several popular herbal therapies for menopausal symptoms including phytoestrogens, black cohosh (Cimicifuga racemosa), dong quai (Angelica sinensis), chast tree (Vitex agnus-castus), and wild Mexican yam. Their use, mechanism of action, and adverse effects are outlined.

Aileron controls for wind turbine applications

NASA Technical Reports Server (NTRS)

Miller, D. R.; Puthoff, R. L.

1984-01-01

Horizontal axis wind turbines which utilize partial or full variable blade pitch to regulate rotor speed were examined. The weight and costs of these systems indicated a need for alternate methods of rotor control. Aileron control is an alternative which has potential to meet this need. Aileron control rotors were tested on the Mod-O wind turbine to determine their power regulation and shutdown characteristics. Test results for a 20 and 38 percent chord aileron control rotor are presented. Test is shown that aileron control is a viable method for safety for safely controlling rotor speed, following a loss of general load.

Invasive and noninvasive dental analgesia techniques.

PubMed

Estafan, D J

1998-01-01

Although needle-administered local anesthesia has been an essential tool of modern dentistry, it has also been responsible for many patients' fears of dental visits. Several new techniques have recently evolved that may offer viable alternatives. Two of these operate via electronic mechanisms that interfere with pain signals, two others involve transmucosal modes of administration, and a fifth technique involves an intraosseous pathway for anesthesia administration. Each of these techniques has different indications for dental procedures, but none is intended to replace needle administration in dentistry. This overview highlights the salient features of these alternative dental anesthesia techniques.

49 CFR 193.2915 - Alternative power sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Alternative power sources. 193.2915 Section 193.2915 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS... GAS FACILITIES: FEDERAL SAFETY STANDARDS Security § 193.2915 Alternative power sources. An alternative...

Potential of metal-organic frameworks for separation of xenon and krypton.

PubMed

Banerjee, Debasis; Cairns, Amy J; Liu, Jian; Motkuri, Radha K; Nune, Satish K; Fernandez, Carlos A; Krishna, Rajamani; Strachan, Denis M; Thallapally, Praveen K

2015-02-17

CONSPECTUS: The total world energy demand is predicted to rise significantly over the next few decades, primarily driven by the continuous growth of the developing world. With rapid depletion of nonrenewable traditional fossil fuels, which currently account for almost 86% of the worldwide energy output, the search for viable alternative energy resources is becoming more important from a national security and economic development standpoint. Nuclear energy, an emission-free, high-energy-density source produced by means of controlled nuclear fission, is often considered as a clean, affordable alternative to fossil fuel. However, the successful installation of an efficient and economically viable industrial-scale process to properly sequester and mitigate the nuclear-fission-related, highly radioactive waste (e.g., used nuclear fuel (UNF)) is a prerequisite for any further development of nuclear energy in the near future. Reprocessing of UNF is often considered to be a logical way to minimize the volume of high-level radioactive waste, though the generation of volatile radionuclides during reprocessing raises a significant engineering challenge for its successful implementation. The volatile radionuclides include but are not limited to noble gases (predominately isotopes of Xe and Kr) and must be captured during the process to avoid being released into the environment. Currently, energy-intensive cryogenic distillation is the primary means to capture and separate radioactive noble gas isotopes during UNF reprocessing. A similar cryogenic process is implemented during commercial production of noble gases though removal from air. In light of their high commercial values, particularly in lighting and medical industries, and associated high production costs, alternate approaches for Xe/Kr capture and storage are of contemporary research interest. The proposed pathways for Xe/Kr removal and capture can essentially be divided in two categories: selective absorption by dissolution in solvents and physisorption on porous materials. Physisorption-based separation and adsorption on highly functional porous materials are promising alternatives to the energy-intensive cryogenic distillation process, where the adsorbents are characterized by high surface areas and thus high removal capacities and often can be chemically fine-tuned to enhance the adsorbate-adsorbent interactions for optimum selectivity. Several traditional porous adsorbents such as zeolites and activated carbon have been tested for noble gas capture but have shown low capacity, selectivity, and lack of modularity. Metal-organic frameworks (MOFs) or porous coordination polymers (PCPs) are an emerging class of solid-state adsorbents that can be tailor-made for applications ranging from gas adsorption and separation to catalysis and sensing. Herein we give a concise summary of the background and development of Xe/Kr separation technologies with a focus on UNF reprocessing and the prospects of MOF-based adsorbents for that particular application.

The potential contribution of bread buns fortified with beta-carotene-rich sweet potato in Central Mozambique.

PubMed

Low, Jan W; van Jaarsveld, Paul J

2008-06-01

Orange-fleshed sweet potato is an efficacious source of vitamin A. Substituting wheat flour with orange-fleshed sweet potato in processed products could reduce foreign exchange outlays, create new markets for producers, and result in increased vitamin A consumption among consumers provided there is adequate retention of beta-carotene during processing. To explore whether substituting 38% of wheat flour (by weight) in bread buns ("golden bread") with boiled and mashed orange-fleshed sweet potato from fresh roots or rehydrated chips would produce economically viable beta-carotene-rich products acceptable to Mozambican rural consumers. Modified local recipes maximized sweet potato content within the limits of consumer acceptability. Sensitivity analysis determined parameters underlying economic viability. Two samples each of buns from five varieties of orange-fleshed sweet potato were analyzed for beta-carotene content. Processed products with at least 15 microg/g product of trans-beta-carotene were considered good sources of vitamin A. Golden bread made from fresh roots of medium-intensity orange-fleshed sweet potato varieties met the good source criterion, but bread from lighter-intensity sweet potato varieties did not. Bread from rehydrated dried chips was not economically viable. Consumers strongly preferred golden bread over pure wheat flour bread because of its heavier texture and attractive appearance. The ratio of the price of wheat flour to that of raw sweet potato root varied from 3.1 to 3.5 among the bakers, whose increase in profit margins ranged from 54% to 92%. Golden bread is a good source of beta-carotene and is economically viable when the price ratio of wheat flour to raw orange-fleshed sweet potato root is at least 1.5. Widespread adoption during sweet potato harvesting periods is feasible; year-round availability requires storage.

Multiple shoot cultures of Ophiorrhiza rugosa var. decumbens Deb and Mondal--a viable renewable source for the continuous production of bioactive Camptotheca alkaloids apart from stems of the parent plant of Nothapodytes foetida (Wight) Sleumer.

PubMed

Gopalakrishnan, Roja; Shankar, Bhavani

2014-02-15

Camptotheca alkaloids were isolated from multiple shoot cultures of O. decumbens (0.056% dry weight) and stems of N. foetida. The cytotoxicity of the extracts and products were tested in a panel of five cell lines. Crude extract from O. decumbens (Cr-Od) and N. foetida (Cr-Nf) showed more potent cytotoxic activity as compared to the isolated camptothecin from O. decumbens (CPT-Od) and N. foetida (CPT-Nf). CPT isolated from shoot cultures contained biological activity suggesting the possibility of using this system of O. decumbens as a renewable source for the production of camptotheca alkaloids. 9-Methoxy camptothecin (9-mCPT), isolated from N. foetida, was a very effective cytotoxic agent as compared to Cr-Nf or CPT-Nf. The IC50 of 9-mCPT was 0.84, 0.32, and 0.35 μg/ml for A549, MCF7 and Jurkat cell lines and >3 μg/ml for U937. Viability assays using MTT dye were further confirmed by assessing extent of apoptosis in these cells. These findings suggest that shoot cultures of O. decumbens offer a rich alternative plant source for the anticancer compound, CPT and 9-mCPT is a more potent compound in N. foetida as compared to CPT. Copyright © 2013 Elsevier GmbH. All rights reserved.

Influence of nutritional and physicochemical variables on PHB production from raw glycerol obtained from a Colombian biodiesel plant by a wild-type Bacillus megaterium strain.

PubMed

Moreno, Paalo; Yañez, Camilo; Cardozo, Nilo Sérgio Medeiros; Escalante, Humberto; Combariza, Marianny Y; Guzman, Carolina

2015-12-25

Biodegradable polymers are currently viable alternatives to traditional synthetic polymers. For instance, polyhydroxybutyrate (PHB) is intracellularly produced and accumulated by Bacillus species, among others. This study reports several wild-type Bacillus strains with the ability to accumulate PHB using raw glycerol from biodiesel production as the sole carbon source. Out of 15 strains from different sources, B. megaterium B2 was selected as the most promising strain for further statistical optimization of the medium composition. Plackett-Burman and central composite designs were used to establish key variables and optimal culture conditions for PHB production using both 250-mL shake flasks and a 7.5-L bioreactor. Temperature and concentrations of glycerol and Na2HPO4 are the experimental variables with the most significant influence on PHB production by B2. After 14 hours of fermentation in shake flasks with optimized medium, B2 produced 0.43 g/L of PHB with a 34% accumulation in the cells. In contrast, under the same conditions, a maximum PHB concentration of 1.20 g/L in the bioreactor was reached at 11 hours. These values correspond to a 48% and 314% increase in PHB production compared to the initial culture conditions. These results suggest the potential of B2 as a PHB producer using raw glycerol, which is an inexpensive, abundant and readily available carbon source. Copyright © 2015 Elsevier B.V. All rights reserved.

Refinement of Perioperative Feeding in a Mouse Model of Vertical Sleeve Gastrectomy.

PubMed

Doerning, Carolyn M; Burlingame, Lisa A; Lewis, Alfor G; Myronovych, Andriy; Seeley, Randy J; Lester, Patrick A

2018-05-01

Provision of liquid enteral nutrition (LEN) during the perioperative period is standard practice for rodents undergoing bariatric surgery, yet these diets are associated with several challenges, including coagulation of the liquid diet within the delivery system and decreased postoperative consumption. We investigated the use of a commercially available high-calorie dietary gel supplement (DG) as an alternative food source for mice during the perioperative period. C57BL/6J male mice were fed high-fat diet for 8 to 10 wk prior to surgery. The study groups were: vertical sleeve gastrectomy (VSG) +DG, VSG+LEN, sham surgery+DG, and sham+LEN. Food and water intakes, body weight, and body fat composition was monitored throughout the study. Mice that received DG lost significantly more weight preoperatively than those fed LEN. However, during the postoperative period, body weight, body fat composition, and water and caloric intake were similar among all experimental diet groups. Three mice in the VSG+LEN group were euthanized due to clinical illness during the course of the study. In summary, feeding a high-calorie DG to mice undergoing VSG surgery is a viable alternative to LEN, given that DG does not significantly affect the surgical model of weight loss or result in adverse clinical outcomes. We recommend additional metabolic characterization of DG supplementation to ensure that this novel diet does not confound specific research goals in the murine VSG model.

[Advances in metabolic engineering for the microbial production of naturally occurring terpenes-limonene and bisabolene: a mini review].

PubMed

Pang, Yaru; Hu, Zhihui; Xiao, Dongguang; Yu, Aiqun

2018-01-25

Limonene (C₁₀H₁₆) and bisabolene (C₁₅H₂₄) are both naturally occurring terpenes in plants. Depending on the number of C₅ units, limonene and bisabolene are recognized as representative monoterpenes and sesquiterpenes, respectively. Limonene and bisabolene are important pharmaceutical and nutraceutical products used in the prevention and treatment of cancer and many other diseases. In addition, they can be used as starting materials to produce a range of commercially valuable products, such as pharmaceuticals, nutraceuticals, cosmetics, and biofuels. The low abundance or yield of limonene and bisabolene in plants renders their isolation from plant sources non-economically viable. Isolation of limonene and bisabolene from plants also suffers from low efficiency and often requires harsh reaction conditions, prolonged reaction times, and expensive equipment cost. Recently, the rapid developments in metabolic engineering of microbes provide a promising alternative route for producing these plant natural products. Therefore, producing limonene and bisabolene by engineering microbial cells into microbial factories is becoming an attractive alternative approach that can overcome the bottlenecks, making it more sustainable, environmentally friendly and economically competitive. Here, we reviewed the status of metabolic engineering of microbes that produce limonene and bisabolene including microbial hosts, key enzymes, metabolic pathways and engineering of limonene/bisabolene biosynthesis. Furthermore, key challenges and future perspectives were discussed.

Prospects for conversion of solar energy into chemical fuels: the concept of a solar fuels industry.

PubMed

Harriman, Anthony

2013-08-13

There is, at present, no solar fuels industry anywhere in the world despite the well-publicized needs to replace our depleting stock of fossil fuels with renewable energy sources. Many obstacles have to be overcome in order to store sunlight in the form of chemical potential, and there are severe barriers to surmount in order to produce energy on a massive scale, at a modest price and in a convenient form. It is also essential to allow for the intermittent nature of sunlight, its diffusiveness and variability and to cope with the obvious need to use large surface areas for light collection. Nonetheless, we have no alternative but to devise viable strategies for storage of sunlight as biomass or chemical feedstock. Simple alternatives, such as solar heating, are attractive in terms of quick demonstrations but are not the answer. Photo-electrochemical devices might serve as the necessary machinery by which to generate electronic charge but the main problem is to couple these charges to the multi-electron catalysis needed to drive energy-storing chemical reactions. Several potential fuels (CO, H₂, HCOOH, NH₃, O₂, speciality organics, etc.) are possible, but the photochemical reduction of CO₂ deserves particular mention because of ever-growing concerns about overproduction of greenhouse gases. The prospects for achieving these reactions under ambient conditions are considered herein.

Commuter exposure to black carbon, carbon monoxide, and noise in the mass transport khlong boats of Bangkok, Thailand

NASA Astrophysics Data System (ADS)

Ziegler, A. D.; Velasco, E.; Ho, K. J.

2013-12-01

Khlong (canal) boats are a unique mass transport alternative in the congested city of Bangkok. Canals and rivers provide exclusive transit-ways for reducing the commuting time of thousands of city residents daily. However, as a consequence of the service characteristics and boats design and state of repair, they can represent a potential public health risk and an important source of black carbon and greenhouse gases. This work quantifies commuter exposure to black carbon, CO and noise when waiting for and travelling in these diesel fueled boats. Exposure to toxic pollutants and acute noise is similar or worse than for other transportation modes. Mean black carbon concentrations observed at one busy pier and along the main canal were much higher than ambient concentrations at sites impacted by vehicular traffic. Concentrations of CO were similar to those reported for roadside areas of Bangkok. The equivalent continuous sound levels registered at the landing pier were similar to those reported for roadsides, but values recorded inside the boats were significantly higher. We believe that the boat service is a viable alternative mode of mass transport, but public safety could be improved to provide a high quality service, comparable to modern rail systems or emerging bus rapid transit systems. These investments would also contribute to reduce the emission of black carbon and other greenhouse and toxic pollutants.

Larvicidal Potential of the Halogenated Sesquiterpene (+)-Obtusol, Isolated from the Alga Laurencia dendroidea J. Agardh (Ceramiales: Rhodomelaceae), against the Dengue Vector Mosquito Aedes aegypti (Linnaeus) (Diptera: Culicidae)

PubMed Central

Salvador-Neto, Orlando; Gomes, Simone Azevedo; Soares, Angélica Ribeiro; Machado, Fernanda Lacerda da Silva; Samuels, Richard Ian; Nunes da Fonseca, Rodrigo; Souza-Menezes, Jackson; Moraes, Jorge Luiz da Cunha; Campos, Eldo; Mury, Flávia Borges; Silva, José Roberto

2016-01-01

Dengue is considered a serious public health problem in many tropical regions of the world including Brazil. At the moment, there is no viable alternative to reduce dengue infections other than controlling the insect vector, Aedes aegypti Linnaeus. In the continuing search for new sources of chemicals targeted at vector control, natural products are a promising alternative to synthetic pesticides. In our work, we investigated the toxicity of a bioactive compound extracted from the red alga Laurencia dendroidea J. Agardh. The initial results demonstrated that crude extracts, at a concentration of 5 ppm, caused pronounced mortality of second instar A. aegypti larvae. Two molecules, identified as (−)-elatol and (+)-obtusol were subsequently isolated from crude extract and further evaluated. Assays with (−)-elatol showed moderate larvicidal activity, whereas (+)-obtusol presented higher toxic activity than (−)-elatol, with a LC50 value of 3.5 ppm. Histological analysis of the larvae exposed to (+)-obtusol revealed damage to the intestinal epithelium. Moreover, (+)-obtusol-treated larvae incubated with 2 µM CM-H2DCFDA showed the presence of reactive oxygen species, leading us to suggest that epithelial damage might be related to redox imbalance. These results demonstrate the potential of (+)-obtusol as a larvicide for use against A. aegypti and the possible mode of action of this compound. PMID:26821032

48 CFR 906.202 - Establishing or maintaining alternative sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... maintaining alternative sources. 906.202 Section 906.202 Federal Acquisition Regulations System DEPARTMENT OF ENERGY COMPETITION ACQUISITION PLANNING COMPETITION REQUIREMENTS Full and Open Competition After Exclusion of Sources 906.202 Establishing or maintaining alternative sources. (b)(1) Every proposed contract...

48 CFR 406.202 - Establishing or maintaining alternative sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... maintaining alternative sources. 406.202 Section 406.202 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Full and Open Competition After Exclusion of Sources 406.202 Establishing or maintaining alternative sources. The Senior Procurement...

48 CFR 1406.202 - Establishing or maintaining alternative sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... maintaining alternative sources. 1406.202 Section 1406.202 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Full and Open Competition After Exclusion of Sources 1406.202 Establishing or maintaining alternative sources. HCAs are...

48 CFR 1306.202 - Establishing or maintaining alternative sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... maintaining alternative sources. 1306.202 Section 1306.202 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Full and Open Competition After Exclusion of Sources 1306.202 Establishing or maintaining alternative sources. The authority to...

Historical contingency and the gradual evolution of metabolic properties in central carbon and genome-scale metabolisms

PubMed Central

2014-01-01

Background A metabolism can evolve through changes in its biochemical reactions that are caused by processes such as horizontal gene transfer and gene deletion. While such changes need to preserve an organism’s viability in its environment, they can modify other important properties, such as a metabolism’s maximal biomass synthesis rate and its robustness to genetic and environmental change. Whether such properties can be modulated in evolution depends on whether all or most viable metabolisms – those that can synthesize all essential biomass precursors – are connected in a space of all possible metabolisms. Connectedness means that any two viable metabolisms can be converted into one another through a sequence of single reaction changes that leave viability intact. If the set of viable metabolisms is disconnected and highly fragmented, then historical contingency becomes important and restricts the alteration of metabolic properties, as well as the number of novel metabolic phenotypes accessible in evolution. Results We here computationally explore two vast spaces of possible metabolisms to ask whether viable metabolisms are connected. We find that for all but the simplest metabolisms, most viable metabolisms can be transformed into one another by single viability-preserving reaction changes. Where this is not the case, alternative essential metabolic pathways consisting of multiple reactions are responsible, but such pathways are not common. Conclusions Metabolism is thus highly evolvable, in the sense that its properties could be fine-tuned by successively altering individual reactions. Historical contingency does not strongly restrict the origin of novel metabolic phenotypes. PMID:24758311

Adaptive Cluster Sampling for Forest Inventories

Treesearch

Francis A. Roesch

1993-01-01

Adaptive cluster sampling is shown to be a viable alternative for sampling forests when there are rare characteristics of the forest trees which are of interest and occur on clustered trees. The ideas of recent work in Thompson (1990) have been extended to the case in which the initial sample is selected with unequal probabilities. An example is given in which the...

Alumni of Varying Eras: An Examination of the Differences in Factors That Influence Feelings of Connectivity and Reasons for Giving

ERIC Educational Resources Information Center

Galligan, Christopher J.

2013-01-01

This study addressed the economic challenges confronting public institutions of higher education by examining a viable, alternative revenue stream: alumni giving. The purpose of this study was to examine differences in factors that influence feelings of connectivity and reasons for giving of alumni of varying eras at a public, regional…

Consumer Interests Annual. Annual Conference of the American Council on Consumer Interests (42nd, Nashville, Tennessee, March 27-30, 1996).

ERIC Educational Resources Information Center

Folk, Karen Fox, Ed.

Among the 99 conference papers presented are the following: "Whither the Consumer Interest: The Role of Consumer Education and Research in an Era of Public Reinvention" (Colien Hefferan); "The Scientific Foundations of Consumer Advice: Some Comments" (E. Scott Maynes); "Self-Employment: A Viable Economic Alternative for the California Hispanic…

If It Ain't Survival...It's Catastrophe: A Social Studies Curriculum for a Modern World.

ERIC Educational Resources Information Center

Knox, Gary A.

The goal of the Marin Social Studies Project was to present a relevant and comprehensive design for American social studies education and to serve as a change agent by providing rational and viable alternatives to present practices. This paper documents the development of this curriculum design, defining the purpose of teaching and the nature of…

The Leapfrogging Opportunity: The Role of Education in Sustainable Development and Climate Change Mitigation

ERIC Educational Resources Information Center

Sarabhai, Kartikeya; Vyas, Purvi

2017-01-01

Recognising that the current paradigm of development which is fossil fuel based and high on consumption and waste is not a viable option for the future, developing countries need to take an alternative path towards sustainable development. All too often, they merely imitate solutions which are already being discarded in the West. The confidence…

Using Virtual Field Trips to Connect Students with University Scientists: Core Elements and Evaluation of zipTrips[TM

ERIC Educational Resources Information Center

Adedokun, Omolola A.; Hetzel, Kristin; Parker, Loran Carleton; Loizzo, Jamie; Burgess, Wilella D.; Robinson, J. Paul

2012-01-01

Physical field trips to scientists' work places have been shown to enhance student perceptions of science, scientists and science careers. Although virtual field trips (VFTs) have emerged as viable alternatives (or supplements) to traditional physical fieldtrips, little is known about the potential of virtual field trips to provide the same or…

Evaluation of E-Rat, a Computer-based Rat Dissection in Terms of Student Learning Outcomes.

ERIC Educational Resources Information Center

Predavec, Martin

2001-01-01

Presents a study that used computer-based rat anatomy to compare student learning outcomes from computer-based instruction with a conventional dissection. Indicates that there was a significant relationship between the time spent on both classes and the marks gained. Shows that computer-based instruction can be a viable alternative to the use of…

Potential Cost Savings of Contrast-Enhanced Digital Mammography.

PubMed

Patel, Bhavika K; Gray, Richard J; Pockaj, Barbara A

2017-06-01

The purpose of this article is to discuss whether the sensitivity and specificity of contrast-enhanced digital mammography (CEDM) render it a viable diagnostic alternative to breast MRI. That CEDM couples low-energy images (comparable to the diagnostic quality of standard mammography) and subtracted contrast-enhanced mammograms make it a cost-effective modality and a realistic substitute for the more costly breast MRI.

Environmental Exposure Effects on Composite Materials for Commercial Aircraft

NASA Technical Reports Server (NTRS)

Hoffman, D. J.

1980-01-01

The test program concentrates on three major areas: flight exposure; ground based exposure; and accelerated environmental effects and data correlation. Among the parameters investigated were: geographic location, flight profiles, solar heating effects, ultraviolet degradation, retrieval times, and test temperatures. Data from the tests can be used to effectively plan the cost of production and viable alternatives in materials selection.

Factors Affecting the Design of Short-Term Study-Abroad Programs: An Exploratory Study of Two Business Schools

ERIC Educational Resources Information Center

Ramakrishna, Hindupur; Sarkar, Avijit; Vijayaraman, Bindiganavale

2016-01-01

Study-abroad programs have played a significant role in globalization of business curricula over the years. Short-term study-abroad programs (STSAPs) are proliferating in business schools and provide a viable alternative of studying abroad to students who are unable to participate in programs of longer durations due to disruption in family, work,…

An alternative to real estate ownership.

PubMed

Scarborough, Sydney

2004-05-01

Partnering with healthcare real estate managers and investors is one way to generate capital, improve cash flow, and minimize the management costs of developing and operating outpatient properties without sacrificing control of strategic locations or facilities. Eight simple steps can help you identify and select viable strategic healthcare real estate partners and negotiate effective monetization (sale of property title) agreements with them.

Estimating botanical composition by the dry-weight-rank method in California's annual grasslands

Treesearch

Raymond D. Ratliff; William E. Frost

1990-01-01

The dry-weight-rank method of estimating botanical composition on California's annual grasslands is a viable alternative to harvesting and sorting or methods using points. Two data sets of sorted species weights were available. One spanned nine years with quadrats harvested at peak of production. The second spanned one growing season with 20 harvest dates. Two...

Alternative timing of carbaryl treatments for protecting lodgepole pine from mortality attributed to mountain pine beetle

Treesearch

Christopher J. Fettig; A.Steve Munson; Kenneth E. Gibson

2015-01-01

Carbaryl is regarded among the most effective, economically viable, and ecologically-compatible insecticides available for protecting conifers from bark beetle attack in the western United States. Treatments are typically applied in spring prior to initiation of bark beetle flight for that year. We evaluated the efficacy of spring and fall applications for protecting...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Witek, Barbara

Research has shown that biofeedback is a viable alternative treatment especially for disorders like headache and hypertension. The aim of this review paper is to illustrate ideas of a promising application of electroencephalograph (EEG) in biofeedback. This sort of biofeedback is called neurofeedback and its efficacy in treating epilepsy and Attention Deficit Hyperactivity Disorder (ADHD) is discussed. Lastly, a brief history of the study of neurofeedback is presented.

Microbial Survey of a Full-Scale, Biologically Active Filter for Treatment of Drinking Water

PubMed Central

DeBry, Ronald W.; Lytle, Darren A.

2012-01-01

The microbial community of a full-scale, biologically active drinking water filter was surveyed using molecular techniques. Nitrosomonas, Nitrospira, Sphingomonadales, and Rhizobiales dominated the clone libraries. The results elucidate the microbial ecology of biological filters and demonstrate that biological treatment of drinking water should be considered a viable alternative to physicochemical methods. PMID:22752177

Job Sharing. A New Pattern for Quality of Work and Life.

ERIC Educational Resources Information Center

Meier, Gretl S.

Job sharing, a new option in permanent part-time employment, is attracting national attention as a viable alternative to more traditional patterns of work. Job sharing is defined as an arrangement whereby two employees hold a position together, whether they are as a team jointly responsible for the whole or separately for each half, dividing time,…

A Qualitative Approach to Understanding the Role of Lecture Capture in Student Learning Experiences

ERIC Educational Resources Information Center

Hall, Gareth; Ivaldi, Antonia

2017-01-01

Lectures continue to be the dominant form of university teaching, and lecture capture technologies are tentatively taken up to support this form of delivery, rather than being used as a viable alternative. Much of the previous research, however, has been self-reports or survey-based, with far less attention given to qualitative explorations. This…

Formation and operation of a captive insurance company for malpractice coverage.

PubMed

Townsend, R W

1988-01-01

With the onset of the "malpractice crisis" of spiralling insurance costs in the 1970s, many medical groups began viewing self-insurance as a viable alternative to conventional carriers. Captive insurance companies are not without their risks, but continue to hold promise for controlling escalating insurance costs and providing a positive cash flow for the parent company.

Quantum probability and cognitive modeling: some cautions and a promising direction in modeling physics learning.

PubMed

Franceschetti, Donald R; Gire, Elizabeth

2013-06-01

Quantum probability theory offers a viable alternative to classical probability, although there are some ambiguities inherent in transferring the quantum formalism to a less determined realm. A number of physicists are now looking at the applicability of quantum ideas to the assessment of physics learning, an area particularly suited to quantum probability ideas.

Biodegradation of Mustard

DTIC Science & Technology

1994-07-01

hydrolyzed during incubation in the aqueous medium used for growth of the microorganism. Microorganisms possessing an enzyme system functional against mustard...indicated. Acidophilic Thiobacillus appear to have limited use for mustard breakdown except for the halotolerant T. DrosDerus, originally isolated from a...microorganisms for mustard breakdown is a viable alternative. Enzymes of halophilic and thermophilic microorganisms are able to function in the presence organic

Social Capital: A Neglected Resource to Create Viable and Sustainable Youth Economic Groups in Urban Tanzania

ERIC Educational Resources Information Center

Manyerere, David J.

2015-01-01

There has been an alarming increase in the rate of unemployment among active urban population in Tanzania whereby the youth are severely affected. In this regard Youth Economic Groups (YEGs) program was formed as one among the best alternative strategies to address this perennial problem. Membership in YEGs act as a means to complement youth…

Analysis of Diurnal Variations in Energy Footprint and Its Associated Carbon Emission for Water Supply and Reuse in Arid and Semi-Arid Areas

NASA Astrophysics Data System (ADS)

Sobhani, Reza

Arid and semi-arid regions throughout the world face water scarcity. Conventional water supply portfolio of these regions encompassed limited surface water, groundwater, and imported water. Current technological innovations technically and economically supplemented new water sources i.e., reclaimed water, desalted water and the groundwater sources that were not potable. The need for more efficient and alternative sources of drinking water supply necessitates studying the impediments e.g., intensive energy required, and emerging concern of the carbon emission. This dissertation discusses the challenges of energy footprint and its carbon emission among the processes involved in water supplies in the aforementioned regions. The conducted studies present time-dependent energy footprint analyses of different water reclamation and reuse processes. This study discusses the energy consumption in four main energy intensive processes inclusive of: activated sludge, microfiltration, reverse osmosis, and advanced oxidation with UV/ H2O2. The results indicate how the diurnal variations of different environmental parameters (e.g. flow and pollutant concentration) amplify the energy footprint variation among these processes. Meanwhile, the results show, due to the different power sources diurnally employed to provide electrical energy, the energy-associated carbon emission has more drastic variation in diurnal period compared to the energy footprint variation. In addition, this study presents the energy footprint of a modular process for treating local brackish groundwater by employing a combination of pellet reactor for radium and hardness minimization, reverse osmosis with intermediate precipitation, and concentrated brine crystallization to achieve high recovery with zero liquid discharge. Also it compares the energy footprint of the aforementioned process with the alternative option (i.e. desalted seawater conveyance with substantial lift). Finally, in coastal regions characterized by water scarcity, such as Southern California, groundwater containing chromophoric dissolved organic matter is a viable source of water supply. However, the seawater intrusion increased the concentration of bromide in extracted groundwater. Bromide, a precursor to bromate formation is regulated by USEPA as a potential carcinogen. This study compares the energy footprint among the two processes utilized for treatment of highly colored groundwater (i.e. nanofiltration and ozone injection coupled with biologically activated carbon) and discusses the impacts of bromate formation among these processes.

Psychiatry, mental health nurses, and invisible power: Exploring a perturbed relationship within contemporary mental health care.

PubMed

Cutcliffe, John; Happell, Brenda

2009-04-01

Interpersonal relationships, although considered to be the cornerstone of therapeutic engagement, are replete with issues of power; yet, the concept of 'invisible power' within such formal mental health care relationships is seldom explored and/or critiqued in the literature. This paper involves an examination of power in the interpersonal relationship between the mental health nurse and the consumer. Issues of power are emphasized by drawing on examples from clinical experiences, each of which is then deconstructed as an analytical means to uncover the different layers of power. This examination highlights the existence of both obscure and seldomly acknowledged invisible manifestations of power that are inherent in psychiatry and interpersonal mental health nursing. It also identifies that there is an orthodoxy of formal mental health care that perhaps is best described as 'biopsychiatry' (or 'traditional psychiatry'). Within this are numerous serious speech acts and these provide the power for mental health practitioners to act in particular ways, to exercise control. The authors challenge this convention as the only viable discourse: a potentially viable alternative to the current of formal mental health care does exist and, most importantly, this alternative is less tied to the use of invisible power.

48 CFR 2406.202 - Establishing or maintaining alternative sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... alternative sources. 2406.202 Section 2406.202 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Full and Open Competition After Exclusion of Sources 2406.202 Establishing or maintaining alternative sources. (b)(1) The...

48 CFR 606.202 - Establishing or maintaining alternate sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... maintaining alternate sources. 606.202 Section 606.202 Federal Acquisition Regulations System DEPARTMENT OF STATE COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Full and Open Competition After Exclusion of Sources 606.202 Establishing or maintaining alternate sources. The Procurement Executive is the...

Full circle to in-house facilities services.

PubMed

Payne, Trevor

2002-08-01

Careful consideration must be taken prior to in-sourcing in order to ensure that the decision is right for the organisation. There will be pressure to go for the quick fix, or the option that involves the least pain or takes the least time (this may be a knee jerk reaction to go straight back out to the market). Contractors will be alert to this due to market intelligence and as a result one problem may be solved but a number of others created as the organisation is put over yet another barrel. Before any decision is taken, an analysis of the circumstances relating to the outsourced services will need to be undertaken. There are several stages to go through when considering in-sourcing and on the whole the steps will mirror those that need to be considered when outsourcing services in the first instance. It is important to recognise that the change management process associated with in-sourcing services will need to be carefully managed. This point cannot be stressed enough. In-sourcing will require management of the outgoing contractor, the in-house team and the customers during the mobilisation phase. A facilities strategy that is aligned to the organisation's strategic direction--sharing core values and goals alongside a good specification are essential. To ensure services are delivered as specified, a robust and effective monitoring system will need to be developed and put into operation. Just as all organisations are different, the drivers influencing the in-sourcing decision will be different--with factors relevant to the host organisation. If in-sourcing has been thoroughly and carefully considered there is absolutely no reason why it should not be effective (as long as it is specified, resourced, managed and monitored in an appropriate manner). In-sourcing is now being considered as a viable alternative to outsourcing, as a vehicle to add value, a sense of corporatism and team spirit to the organisation.

Quantitative assessment of viable cells of Lactobacillus plantarum strains in single, dual and multi-strain biofilms.

PubMed

Fernández Ramírez, Mónica D; Kostopoulos, Ioannis; Smid, Eddy J; Nierop Groot, Masja N; Abee, Tjakko

2017-03-06

Biofilms of Lactobacillus plantarum are a potential source for contamination and recontamination of food products. Although biofilms have been mostly studied using single species or even single strains, it is conceivable that in a range of environmental settings including food processing areas, biofilms are composed of multiple species with each species represented by multiple strains. In this study six spoilage related L. plantarum strains FBR1-FBR6 and the model strain L. plantarum WCFS1 were characterised in single, dual and multiple strain competition models. A quantitative PCR approach was used with added propidium monoazide (PMA) enabling quantification of intact cells in the biofilm, representing the viable cell fraction that determines the food spoilage risk. Our results show that the performance of individual strains in multi-strain cultures generally correlates with their performance in pure culture, and relative strain abundance in multi-strain biofilms positively correlated with the relative strain abundance in suspended (planktonic) cultures. Performance of individual strains in dual-strain biofilms was highly influenced by the presence of the secondary strain, and in most cases no correlation between the relative contributions of viable planktonic cells and viable cells in the biofilm was noted. The total biofilm quantified by CV staining of the dual and multi-strain biofilms formed was mainly correlated to CV values of the dominant strain obtained in single strain studies. However, the combination of strain FBR5 and strain WCFS1 showed significantly higher CV values compared to the individual performances of both strains indicating that total biofilm formation was higher in this specific condition. Notably, L. plantarum FBR5 was able to outgrow all other strains and showed the highest relative abundance in dual and multi-strain biofilms. All the dual and multi-strain biofilms contained a considerable number of viable cells, representing a potential source of contamination. Copyright © 2016 Elsevier B.V. All rights reserved.

Spray combustion modeling

NASA Technical Reports Server (NTRS)

Bellan, J.

1997-01-01

Concern over the future availability of high quality liquid fuels or use in furnaces and boilers prompted the U. S. Department of Energy (DOE) to consider alternate fuels as replacements for the high grade liquid fuels used in the 1970's and 1980's. Alternate fuels were defined to be combinations of a large percentage of viscous, low volatility fuels resulting from the low end of distillation mixed with a small percentage of relatively low viscosity, high volatility fuels yielded by the high end of distillation. The addition of high volatility fuels was meant to promote desirable characteristics to a fuel that would otherwise be difficult to atomize and burn and whose combustion would yield a high amount of pollutants. Several questions thus needed to be answered before alternate fuels became commercially viable. These questions were related to fuel atomization, evaporation, ignition, combustion and pollutant formation. This final report describes the results of the most significant studies on ignition and combustion of alternative fuels.

Cost-benefit comparison of the Oxford Knee score and the American Knee Society score in measuring outcome of total knee arthroplasty.

PubMed

Medalla, Greg Anthony; Moonot, Pradeep; Peel, Tamlyn; Kalairajah, Yegappan; Field, Richard E

2009-06-01

The American Knee Society score (AKSS) and the Oxford Knee score (OKS) are validated outcome measures for evaluation of total knee arthroplasties (TKAs). We investigated whether patient self-assessment using the OKS offers a viable alternative to clinical review using the AKSS. Preoperative, 2-year, 5-year, and 10-year postoperative OKS and AKSS were reviewed from TKA patients. The scores were analyzed using the Pearson correlation. There was good correlation of OKS and AKSS at 2 years. This implies that patient self-assessment is a viable screening tool to identify which patients require clinical review, at 2 years, after TKA. However, the moderate correlation at 5 and 10 years indicates that clinical evaluation remains necessary at these time points.

Solar disinfection of infectious biomedical waste: a new approach for developing countries.

PubMed

Chitnis, V; Chitnis, S; Patil, S; Chitnis, D

2003-10-18

Poor developing countries cannot afford expensive technologies such as incineration for management of infectious biomedical waste. We assessed solar heating as an alternative technology. We immersed simulated infectious waste with added challenge bacteria in water in a box-type solar cooker, which was left in the sun for 6 h. In 24 sets of observations, the amount of viable bacteria was reduced by about 7 log. We also tested infectious medical waste with a heavy load of bacteria (10(8)-10(9)/g) from our hospital's burn unit for solar heat disinfection in 20 experiments. Our results showed a similar 7 log reduction in the amount of viable bacteria. Solar heating thus seems to be a cheap method to disinfect infectious medical waste in less economically developed countries.

Spatial optimization of cropping pattern for sustainable food and biofuel production with minimal downstream pollution.

PubMed

Femeena, P V; Sudheer, K P; Cibin, R; Chaubey, I

2018-04-15

Biofuel has emerged as a substantial source of energy in many countries. In order to avoid the 'food versus fuel competition', arising from grain-based ethanol production, the United States has passed regulations that require second generation or cellulosic biofeedstocks to be used for majority of the biofuel production by 2022. Agricultural residue, such as corn stover, is currently the largest source of cellulosic feedstock. However, increased harvesting of crops residue may lead to increased application of fertilizers in order to recover the soil nutrients lost from the residue removal. Alternatively, introduction of less-fertilizer intensive perennial grasses such as switchgrass (Panicum virgatum L.) and Miscanthus (Miscanthus x giganteus Greef et Deu.) can be a viable source for biofuel production. Even though these grasses are shown to reduce nutrient loads to a great extent, high production cost have constrained their wide adoptability to be used as a viable feedstock. Nonetheless, there is an opportunity to optimize feedstock production to meet bioenergy demand while improving water quality. This study presents a multi-objective simulation optimization framework using Soil and Water Assessment Tool (SWAT) and Multi Algorithm Genetically Adaptive Method (AMALGAM) to develop optimal cropping pattern with minimum nutrient delivery and minimum biomass production cost. Computational time required for optimization was significantly reduced by loose coupling SWAT with an external in-stream solute transport model. Optimization was constrained by food security and biofuel production targets that ensured not more than 10% reduction in grain yield and at least 100 million gallons of ethanol production. A case study was carried out in St. Joseph River Watershed that covers 280,000 ha area in the Midwest U.S. Results of the study indicated that introduction of corn stover removal and perennial grass production reduce nitrate and total phosphorus loads without compromising on food and biofuel production. Optimization runs yielded an optimal cropping pattern with 32% of watershed area in stover removal, 15% in switchgrass and 2% in Miscanthus. The optimal scenario resulted in 14% reduction in nitrate and 22% reduction in total phosphorus from the baseline. This framework can be used as an effective tool to take decisions regarding environmentally and economically sustainable strategies to minimize the nutrient delivery at minimal biomass production cost, while simultaneously meeting food and biofuel production targets. Copyright © 2018 Elsevier Ltd. All rights reserved.

48 CFR 3006.202 - Establishing or maintaining alternative sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... COMPETITION REQUIREMENTS Full and Open Competition After Exclusion of Sources 3006.202 Establishing or maintaining alternative sources. (b)(1) The HCA is delegated authority to approve a D&F in support of a... maintaining alternative sources. 3006.202 Section 3006.202 Federal Acquisition Regulations System DEPARTMENT...

Review of alternate automotive engine fuel economy. Final report January-October 78

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, D.; Bolt, J.A.; Huber, P.

This study assessed the potential of alternate automotive engines to meet the fuel economy goals and emission levels of the 1980-1990 period. As part of NHTSA's continuing research in support of the Department of Transportation fuel economy activities, this study reviewed those developments offering viable substitutes for the current spark ignition engine systems. Categories assessed included stratified charge, diesels, turbo charging, rotary/Wankel engines, and the developmental gas turbine and Stirling cycle engines. Results of past and on-going research through 1978 were reviewed along with the development and production status of various alternate engine technologies proposed for automobiles and light trucksmore » through the 1980s. Assessment was then made of the potential fuel economy improvement as a percentage of 1978 baseline data.« less

Expanding Science Knowledge: Enabled by Nuclear Power

NASA Technical Reports Server (NTRS)

Clark, Karla B.

2011-01-01

The availability of Radioisotope Power Sources (RPSs) power opens up new and exciting mission concepts (1) New trajectories available (2) Power for long term science and operations Astonishing science value associated with these previously non-viable missions

Non-intrusive speed sensor. [space shuttle main engine turbopumps

NASA Technical Reports Server (NTRS)

Maram, J.; Wyett, L.

1984-01-01

A computerized literature search was performed to identify candidate technologies for remote, non-intrusive speed sensing applications in Space Shuttle Main Engine (SSME) turbopumps. The three most promising technologies were subjected to experimental evaluation to quantify their performance characteristics under the harsh environmental requirements within the turbopumps. Although the infrared and microwave approaches demonstrated excellent cavitation immunity in laboratory tests, the variable-source magnetic speed sensor emerged as the most viable approach. Preliminary design of this speed sensor encountered no technical obstacles and resulted in viable and feasible speed nut, sensor housing, and sensor coil designs.

Alternative transportation funding sources available to Virginia localities.

DOT National Transportation Integrated Search

2006-01-01

In 2003, the Virginia Department of Transportation developed a list of alternative transportation funding sources available to localities in Virginia. Alternative funding sources are defined as those that are not included in the annual interstate, pr...

Interventions for Detrusor Overactivity: The Case for Multimodal Therapy

PubMed Central

Dmochowski, Roger

2002-01-01

Viable therapeutic alternatives for the management of overactive bladder (OAB) have recently evolved that provide satisfactory symptomatic control for the majority of patients. However, the presupposition that interventions exist as stand-alone entities is not representative of experience in unique populations with the therapeutic benefit of combination therapy, using components drawn from behavioral, physiotherapeutic, neuromodulatory, and, if necessary, surgical alternatives. Even in populations relatively refractory to therapy, the use of multimodal therapy yields additive benefits for patients with OAB symptoms. Herein is detailed the evidence supporting the concept that multimodal therapy provides optimal benefit to patients suffering from this symptom complex. PMID:16986017

Patient-as-observer approach: an alternative method for hand hygiene auditing in an ambulatory care setting.

PubMed

Le-Abuyen, Sheila; Ng, Jessica; Kim, Susie; De La Franier, Anne; Khan, Bibi; Mosley, Jane; Gardam, Michael

2014-04-01

A survey pilot asked patients to observe the hand hygiene compliance of their health care providers. Patients returned 75.1% of the survey cards distributed, and the overall hand hygiene compliance was 96.8%. Survey results and patient commentary were used to motivate hand hygiene compliance. The patient-as-observer approach appeared to be a viable alternative for hand hygiene auditing in an ambulatory care setting because it educated, engaged, and empowered patients to play a more active role in their own health care. Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

Initial flight test of a Loran-C receiver/data collection system

NASA Technical Reports Server (NTRS)

Fischer, J. P.; Nickum, J. D.

1978-01-01

Development of a low cost Loran C receiver for general aviation use is discussed. The preparation and procedure of a flight test conducted with a receiver design which utilizes a phase locked loop oscillator to track the Loran C signals is described. It is indicated that such a receiver is a viable alternative for future work in developing a low cost Loran-C navigator.

Making Higher Education More Affordable, One Course Reading at a Time: Academic Libraries as Key Advocates for Open Access Textbooks and Educational Resources

ERIC Educational Resources Information Center

Okamoto, Karen

2013-01-01

Open access textbooks (OATs) and educational resources (OERs) are being lauded as a viable alternative to costly print textbooks. Some academic libraries are joining the OER movement by creating guides to open repositories. Others are promoting OATs and OERs, reviewing them, and even helping to create them. This article analyzes how academic…

Neurofeedback—hype or hope?

NASA Astrophysics Data System (ADS)

Witek, Barbara

2007-11-01

Research has shown that biofeedback is a viable alternative treatment especially for disorders like headache and hypertension. The aim of this review paper is to illustrate ideas of a promising application of electroencephalograph (EEG) in biofeedback. This sort of biofeedback is called neurofeedback and its efficacy in treating epilepsy and Attention Deficit Hyperactivity Disorder (ADHD) is discussed. Lastly, a brief history of the study of neurofeedback is presented.

Is On-Line Distance Education a Viable Alternative for Undergraduates? An Experiment with the Students in Georgia, the Professor in Australia.

ERIC Educational Resources Information Center

Dick, Geoffrey N.; Hanna, Mark

This paper reports the results of a study conducted with non-IS undergraduate students undertaking an online distance education class. Although the sample size is small and there is some self-selection, it provides some preliminary answers to what such students see as the advantages and disadvantages of online education, whether these perceptions…

HANFORD MEDIUM-LOW CURIE WASTE PRETREATMENT ALTERNATIVES PROJECT FRACTIONAL CRYSTALLIZATION PILOT SCALE TESTING FINAL REPORT

DOE Office of Scientific and Technical Information (OSTI.GOV)

HERTING DL

2008-09-16

The Fractional Crystallization Pilot Plant was designed and constructed to demonstrate that fractional crystallization is a viable way to separate the high-level and low-activity radioactive waste streams from retrieved Hanford single-shell tank saltcake. The focus of this report is to review the design, construction, and testing details of the fractional crystallization pilot plant not previously disseminated.

Earth land landing alternatives: Lunar transportation system

NASA Technical Reports Server (NTRS)

Meyerson, Robert

1992-01-01

The objectives of this study are as follows: (1) develop a landing option such that it is a viable trade option for future NASA missions; (2) provide NASA programs with solid technical support in the landing systems area; (3) develop the technical staff; and (4) advance the state of landing systems technology to apply to future NASA missions. All results are presented in viewgraph format.

Response to comments on "A bacterium that can grow using arsenic instead of phosphorus"

USGS Publications Warehouse

Wolfe-Simon, Felisa; Blum, Jodi Switzer; Kulp, Thomas R.; Gordon, Gwyneth W.; Hoeft, Shelley E.; Pett-Ridge, Jennifer; Stolz, John F.; Webb, Samuel M.; Weber, Peter K.; Davies, Paul C.W.; Anbar, Ariel D.; Oremland, Ronald S.

2011-01-01

Concerns have been raised about our recent study suggesting that arsenic (As) substitutes for phosphorus in major biomolecules of a bacterium that tolerates extreme As concentrations. We welcome the opportunity to better explain our methods and results and to consider alternative interpretations. We maintain that our interpretation of As substitution, based on multiple congruent lines of evidence, is viable.

Synthesis of an Imidazolidinone Organocatalyst and Its Application in a Diels-Alder Cycloaddition: A Multistep Experiment for the Organic Teaching Laboratory

ERIC Educational Resources Information Center

Murphy, John J.; Driver, Ross B.; Walsh, Ria; Stephens, John C.

2016-01-01

The development of novel, high-yielding, and selective methodologies for the asymmetric synthesis of stereocenters is at the forefront of modern synthetic chemistry research. Organocatalysis can now be viewed as a viable alternative to the use of the sometimes toxic transition-metal catalysts. In this experiment, the simple synthesis of an achiral…

HF RFID versus UHF RFID--Technology for Library Service Transformation at City University of Hong Kong

ERIC Educational Resources Information Center

Ching, Steve H.; Tai, Alice

2009-01-01

Since libraries first used RFID systems in the late 1990s, more and more libraries have identified the advantages of the technology. With advances in HF and UHF RFID, both alternatives are now viable in library applications. While some librarians are still skeptical towards UHF RFID as unproven in the library arena, the City University of Hong…

Field performance of graded northern red oak seedlings planted under four overstory treatments in Tennessee: two-year results

Treesearch

Christopher M. Oswalt; Wayne K. Clatterbuck

2005-01-01

Oak replacement persists as an obstacle to high quality hardwood management, especially on highly productive sites. Difficulties in naturally regenerating oak can be viewed as the result of social and economic constraints imposed by the biological solution, not the lack of a solution. As a result, economically viable alternatives are being explored to maintain oak as...

Golden Rice and 'Golden' crops for human nutrition.

PubMed

Beyer, Peter

2010-11-30

Micronutrients are essential for a healthy life. Humans do not produce micronutrients, and hence they must obtain them through the foodchain. Staple crops are the predominant food source of mankind, but need to be complemented by other foodstuffs because they are generally deficient in one or the other micronutrient. Breeding for micronutrient-dense crops is not always a viable option because of the absence of genetic variability for the desired trait. Moreover, sterility issues and the complex genetic makeup of some crop plants make them unamenable to conventional breeding. In these cases, genetic modification remains the only viable option. The tools to produce a number of micronutrients in staple crops have recently become available thanks to the identification of the genes involved in the corresponding biochemical pathways at an unprecedented rate. Discarding genetic modification as a viable option is definitely not in the interest of human wellbeing. Copyright © 2010 Elsevier B.V. All rights reserved.

48 CFR 1806.202 - Establishing or maintaining alternative sources. (NASA supplements paragraphs (a) and (b))

Code of Federal Regulations, 2010 CFR

2010-10-01

... COMPETITION REQUIREMENTS Full and Open Competition After Exclusion of Sources 1806.202 Establishing or maintaining alternative sources. (NASA supplements paragraphs (a) and (b)) (a) The authority of FAR 6.202 is... alternative sources. (NASA supplements paragraphs (a) and (b)) 1806.202 Section 1806.202 Federal Acquisition...

48 CFR 2406.202 - Establishing or maintaining alternative sources.

Code of Federal Regulations, 2011 CFR

2011-10-01

... maintaining alternative sources. 2406.202 Section 2406.202 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Full and Open Competition After Exclusion of Sources 2406.202 Establishing or maintaining alternative...

The Linearized Bregman Method for Frugal Full-waveform Inversion with Compressive Sensing and Sparsity-promoting

NASA Astrophysics Data System (ADS)

Chai, Xintao; Tang, Genyang; Peng, Ronghua; Liu, Shaoyong

2018-03-01

Full-waveform inversion (FWI) reconstructs the subsurface properties from acquired seismic data via minimization of the misfit between observed and simulated data. However, FWI suffers from considerable computational costs resulting from the numerical solution of the wave equation for each source at each iteration. To reduce the computational burden, constructing supershots by combining several sources (aka source encoding) allows mitigation of the number of simulations at each iteration, but it gives rise to crosstalk artifacts because of interference between the individual sources of the supershot. A modified Gauss-Newton FWI (MGNFWI) approach showed that as long as the difference between the initial and true models permits a sparse representation, the ℓ _1-norm constrained model updates suppress subsampling-related artifacts. However, the spectral-projected gradient ℓ _1 (SPGℓ _1) algorithm employed by MGNFWI is rather complicated that makes its implementation difficult. To facilitate realistic applications, we adapt a linearized Bregman (LB) method to sparsity-promoting FWI (SPFWI) because of the efficiency and simplicity of LB in the framework of ℓ _1-norm constrained optimization problem and compressive sensing. Numerical experiments performed with the BP Salt model, the Marmousi model and the BG Compass model verify the following points. The FWI result with LB solving ℓ _1-norm sparsity-promoting problem for the model update outperforms that generated by solving ℓ _2-norm problem in terms of crosstalk elimination and high-fidelity results. The simpler LB method performs comparably and even superiorly to the complicated SPGℓ _1 method in terms of computational efficiency and model quality, making the LB method a viable alternative for realistic implementations of SPFWI.

Photodynamic therapy of HeLa cell cultures by using LED or laser sources.

PubMed

Etcheverry, María E; Pasquale, Miguel A; Garavaglia, Mario

2016-07-01

The photodynamic therapy (PDT) on HeLa cell cultures was performed utilizing a 637nm LED lamp with 1.06W power and m-tetrahydroxyphenyl chlorin (m-THPC) as photosensitizer and compared to a laser source emitting at 654nm with the same power. Intracellular placement of the photosensitizer and the effect of its concentration (CP), its absorption time (TA) and the illumination time (TI) were evaluated. It was observed that for CP>40μg/ml and TA>24h, m-THPC had toxicity on cells in culture, even in the absence of illumination. For the other tested concentrations, the cells remained viable if not subjected to illumination doses. No effect on cells was observed for CP<0.05μg/ml, TA=48h and TI=10min and they continued proliferating. For drug concentrations higher than 0.05μgml(-1), further deterioration is observed with increasing TA and TI. We evaluated the viability of the cells, before and after the treatment, and by supravital dyes, and phase contrast and fluorescence microscopies, evidence of different types of cell death was obtained. Tetrazolium dye assays after PDT during different times yielded similar results for the 637nm LED lamp with an illuminance three times greater than that of the 654nm laser source. Results demonstrate the feasibility of using a LED lamp as alternative to laser source. Here the main characteristic is not the light coherence but achieving a certain light fluence of the appropriate wavelength on cell cultures. We conclude that the efficacy was achieved satisfactorily and is essential for convenience, accessibility and safety. Copyright © 2016 Elsevier B.V. All rights reserved.

A KPC-Scale X-Ray Jet in the BL Lac Source S5 2007+777

NASA Technical Reports Server (NTRS)

Sambruna, Rita M.; Donato, Davide; Cheung, C.C.; Tavecchio, F.; Maraschi, L.

2008-01-01

X-ray jets in AGN are commonly observed in FRII and FRI radiogalaxies, but rarely in BL Lacs, most probably due to their orientation close to the line of sight and the ensuing foreshortening effects. Only three BL Lacs are known so far to contain a kpc-scale X-ray jet. In this paper, we present the evidence for the existence of a fourth extended X-ray jet in the classical radio-selected source S5 2007+777, which for its hybrid FRI/II radio morphology has been classified as a HYMOR (HYbrid MOrphology Radio source). Our Chandra ACISS observations of this source revealed an X-ray counterpart to the 19"-long radio jet. Interestingly, the X-ray properties of the kpc-scale jet in S5 2007+777 are very similar to those observed in FRII jets. First, the X-ray morphology closely mirrors the radio one, with the X-rays being concentrated in the discrete radio knots. Second, the X-ray continuum of the jet/brightest knot is described by a very hard power law, with photon index gamma(sub x) approximately 1. Third, the optical upper limit from archival HST data implies a concave radio-to-X-ray SED. If the X-ray emission is attributed to IC/CMB with equipartition, strong beaming (delta= 13) is required, implying a very large scale (Mpc) jet. The beaming requirement can be somewhat relaxed assuming a magnetic field lower than equipartition. Alternatively, synchrotron emission from a second population of very high-energy electrons is viable. Comparison to other HYMOR jets detected with Chandra is discussed, as well as general implications for the origin of the FRI/II division.

Growth and seed production of sawtooth oak (`quercus acutissima`) 22 years after direct seeding. Forest Service research note

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goelz, J.C.G.; Carlson, D.W.

Sawtooth oak (Quercus acutissima Carruth) was direct seeded at two locations, one with a poorly drained clay soil and the other with a well-drained silty clay loam. For comparison, Nuttall oak (Q. nuttallii Palmer) was direct seeded on the poorly drained clay soil. On the well-drained silty clay loam, sawtooth oak was 18 ft taller and 2.4 inches larger in d.b.h. at age 22 than on the poorly drained clay soil. On the clay, sawtooth oak grew faster than Nuttall oak, but survival was lower. Almost all sawtooth oaks were producing acorns on both sites; however, no developing acorns weremore » found on the Nuttall oaks. Sawtooth oak is a viable alternative for planting on a wide range of Mississippi Delta forest types. Because sawtooth oak has a poorer form than Nuttal oak, its primary use is as a source of wildlife food. Sawtooth oak could be included in plantings with the multiple objectives of timber production and wildlife use because it grows well and could potentially be used for pulpwood.« less

Colorimetric DNAzyme Biosensor for Convenience Detection of Enterotoxin B Harboring Staphylococcus aureus from Food Samples.

PubMed

Mondal, Bhairab; N, Bhavanashri; Ramlal, Shylaja; Kingston, Joseph

2018-02-14

In the present study, a colorimetric DNAzymes biosensor strategy was devised in combination with immunomagnetic separation for rapid and easy detection of enterotoxin B harboring Staphylococcus aureus from food and clinical samples. The method employs immunocapture of S. aureus and amplification of seb gene by DNAzyme complementary sequence integrated forward primer and with specific reverse primer. The DNAzyme sequence integrated dsDNA PCR products when treated with hemin and TMB (3,3',5,5'-tetramethylbenzidine) in the presence of H 2 O 2 produce colorimetric signal. A linear relationship of optical signal with the initial template of seb was obtained which could be monitored by visually or spectrophotrometrically for qualitative and quantitative detection. The limit of detection for the assay was approximately 10 2 CFU/mL of seb gene harboring target. This method is convenient compared to gel based and ELISA systems. Further, spiking studies and analysis on natural samples emphasized the robustness and applicability of developed method. Altogether, the established assay could be a reliable alternative, low-cost, viable detection tool for the routine investigation of seb from food and clinical sources.

Transitioning glass-ceramic scintillators for diagnostic x-ray imaging from the laboratory to commercial scale

NASA Astrophysics Data System (ADS)

Beckert, M. Brooke; Gallego, Sabrina; Elder, Eric; Nadler, Jason

2016-10-01

This study sought to mitigate risk in transitioning newly developed glass-ceramic scintillator technology from a laboratory concept to commercial product by identifying the most significant hurdles to increased scale. These included selection of cost effective raw material sources, investigation of process parameters with the most significant impact on performance, and synthesis steps that could see the greatest benefit from participation of an industry partner that specializes in glass or optical component manufacturing. Efforts focused on enhancing the performance of glass-ceramic nanocomposite scintillators developed specifically for medical imaging via composition and process modifications that ensured efficient capture of incident X-ray energy and emission of scintillation light. The use of cost effective raw materials and existing manufacturing methods demonstrated proof-of-concept for economical viable alternatives to existing benchmark materials, as well as possible disruptive applications afforded by novel geometries and comparatively lower cost per volume. The authors now seek the expertise of industry to effectively navigate the transition from laboratory demonstrations to pilot scale production and testing to evince the industry of the viability and usefulness of composite-based scintillators.

Streptococcus pneumoniae Is Desiccation Tolerant and Infectious upon Rehydration

PubMed Central

Walsh, Rebecca L.; Camilli, Andrew

2011-01-01

ABSTRACT Streptococcus pneumoniae (pneumococcus) is a frequent colonizer of the nasopharynx and one of the leading causative agents of otitis media, pneumonia, and meningitis. The current literature asserts that S. pneumoniae is transmitted person to person via respiratory droplets; however, environmental surfaces (fomites) have been linked to the spread of other respiratory pathogens. Desiccation tolerance has been to shown to be essential for long-term survival on dry surfaces. This study investigated the survival and infectivity of S. pneumoniae following desiccation under ambient conditions. We recovered viable bacteria after all desiccation periods tested, ranging from 1 h to 4 weeks. Experiments conducted under nutrient limitation indicate that desiccation is a condition separate from starvation. Desiccation of an acapsular mutant and 15 different clinical isolates shows that S. pneumoniae desiccation tolerance is independent of the polysaccharide capsule and is a species-wide phenomenon, respectively. Experiments demonstrating that nondesiccated and desiccated S. pneumoniae strains colonize the nasopharynx at comparable levels, combined with their ability to survive long-term desiccation, suggest that fomites may serve as alternate sources of pneumococcal infection. PMID:21610120

Comparison of electron beam and laser beam powder bed fusion additive manufacturing process for high temperature turbine component materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dryepondt, Sebastien N; Pint, Bruce A; Ryan, Daniel

2016-04-01

The evolving 3D printer technology is now at the point where some turbine components could be additive manufactured (AM) for both development and production purposes. However, this will require a significant evaluation program to qualify the process and components to meet current design and quality standards. The goal of the project was to begin characterization of the microstructure and mechanical properties of Nickel Alloy X (Ni-22Cr-18Fe-9Mo) test bars fabricated by powder bed fusion (PBF) AM processes that use either an electron beam (EB) or laser beam (LB) power source. The AM materials produced with the EB and LB processes displayedmore » significant differences in microstructure and resultant mechanical properties. Accordingly, during the design analysis of AM turbine components, the specific mechanical behavior of the material produced with the selected AM process should be considered. Comparison of the mechanical properties of both the EB and LB materials to those of conventionally processed Nickel Alloy X materials indicates the subject AM materials are viable alternatives for manufacture of some turbine components.« less

Light-induced defects in hybrid lead halide perovskite

NASA Astrophysics Data System (ADS)

Sharia, Onise; Schneider, William

One of the main challenges facing organohalide perovskites for solar application is stability. Solar cells must last decades to be economically viable alternatives to traditional energy sources. While some causes of instability can be avoided through engineering, light-induced defects can be fundamentally limiting factor for practical application of the material. Light creates large numbers of electron and hole pairs that can contribute to degradation processes. Using ab initio theoretical methods, we systematically explore first steps of light induced defect formation in methyl ammonium lead iodide, MAPbI3. In particular, we study charged and neutral Frenkel pair formation involving Pb and I atoms. We find that most of the defects, except negatively charged Pb Frenkel pairs, are reversible, and thus most do not lead to degradation. Negative Pb defects create a mid-gap state and localize the conduction band electron. A minimum energy path study shows that, once the first defect is created, Pb atoms migrate relatively fast. The defects have two detrimental effects on the material. First, they create charge traps below the conduction band. Second, they can lead to degradation of the material by forming Pb clusters.

The Science and Ethics of Induced Pluripotency: What Will Become of Embryonic Stem Cells?

PubMed Central

Zacharias, David G.; Nelson, Timothy J.; Mueller, Paul S.; Hook, C. Christopher

2011-01-01

For over a decade, the field of stem cell research has advanced tremendously and gained new attention in light of novel insights and emerging developments for regenerative medicine. Invariably, multiple considerations come into play, and clinicians and researchers must weigh the benefits of certain stem cell platforms against the costs they incur. Notably, human embryonic stem (hES) cell research has been a source of continued debate, leading to differing policies and regulations worldwide. This article briefly reviews current stem cell platforms, looking specifically at the two existing pluripotent lines available for potential therapeutic applications: hES cells and induced pluripotent stem (iPS) cells. We submit iPS technology as a viable and possibly superior alternative for future medical and research endeavors as it obviates many ethical and resource-related concerns posed by hES cells while prospectively matching their potential for scientific use. However, while the clinical realities of iPS cells appear promising, we must recognize the current limitations of this technology, avoid hype, and articulate ethically acceptable medical and scientific goals. PMID:21719620

Guidelines for use of Hydrogen Fuel in Commercial Vehicles

DOT National Transportation Integrated Search

2008-01-01

Over the next 50 years, hydrogen use is expected to grow dramatically as an automotive and electrical power source fuel. As hydrogen becomes commercially viable, the safety concerns associated with hydrogen systems, equipment, and operation are of co...

Detection of viable Salmonella in ice cream by TaqMan real-time polymerase chain reaction assay combining propidium monoazide.

PubMed

Wang, Yuexia; Yang, Ming; Liu, Shuchun; Chen, Wanyi; Suo, Biao

2015-09-01

Real-time polymerase chain reaction (PCR) allows rapid detection of Salmonella in frozen dairy products, but it might cause a false positive detection result because it might amplify DNA from dead target cells as well. In this study, Salmonella-free frozen ice cream was initially inoculated with heat-killed Salmonella Typhimurium cells and stored at -18°C. Bacterial DNA extracted from the sample was amplified using TaqMan probe-based real-time PCR targeting the invA gene. Our results indicated that DNA from the dead cells remained stable in frozen ice cream for at least 20 days, and could produce fluorescence signal for real-time PCR as well. To overcome this limitation, propidium monoazide (PMA) was combined with real-time PCR. PMA treatment can effectively prevent PCR amplification from heat-killed Salmonella cells in frozen ice cream. The PMA real-time PCR assay can selectively detect viable Salmonella at as low as 10 3  CFU/mL. Combining 18 hours of pre-enrichment with the assay allows for the detection of viable Salmonella at 10 0  CFU/mL and avoiding the false-positive result of dead cells. The PMA real-time PCR assay provides an alternative specifically for detection of viable Salmonella in ice cream. However, when the PMA real-time PCR assay was evaluated in ice cream subjected to frozen storage, it obviously underestimated the contamination situation of viable Salmonella, which might lead to a false negative result. According to this result, the use of enrichment prior to PMA real-time PCR analysis remains as the more appropriate approach. Copyright © 2015. Published by Elsevier B.V.

Culture-Independent Identification of Mycobacterium avium Subspecies paratuberculosis in Ovine Tissues: Comparison with Bacterial Culture and Histopathological Lesions

PubMed Central

Acharya, Kamal R.; Dhand, Navneet K.; Whittington, Richard J.; Plain, Karren M.

2017-01-01

Johne’s disease is a chronic debilitating enteropathy of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP). Current abattoir surveillance programs detect disease via examination of gross lesions and confirmation by histopathological and/or tissue culture, which is time-consuming and has relatively low sensitivity. This study aimed to investigate whether a high-throughput quantitative PCR (qPCR) test is a viable alternative for tissue testing. Intestine and mesenteric lymph nodes were sourced from sheep experimentally infected with MAP and the DNA extracted using a protocol developed for tissues, comprised enzymatic digestion of the tissue homogenate, chemical and mechanical lysis, and magnetic bead-based DNA purification. The extracted DNA was tested by adapting a previously validated qPCR for fecal samples, and the results were compared with culture and histopathology results of the corresponding tissues. The MAP tissue qPCR confirmed infection in the majority of sheep with gross lesions on postmortem (37/38). Likewise, almost all tissue culture (61/64) or histopathology (52/58) positives were detected with good to moderate agreement (Cohen’s kappa statistic) and no significant difference to the reference tests (McNemar’s Chi-square test). Higher MAP DNA quantities corresponded to animals with more severe histopathology (odds ratio: 1.82; 95% confidence interval: 1.60, 2.07). Culture-independent strain typing on tissue DNA was successfully performed. This MAP tissue qPCR method had a sensitivity equivalent to the reference tests and is thus a viable replacement for gross- and histopathological examination of tissue samples in abattoirs. In addition, the test could be validated for testing tissue samples intended for human consumption. PMID:29312970

Culture-Independent Identification of Mycobacterium avium Subspecies paratuberculosis in Ovine Tissues: Comparison with Bacterial Culture and Histopathological Lesions.

PubMed

Acharya, Kamal R; Dhand, Navneet K; Whittington, Richard J; Plain, Karren M

2017-01-01

Johne's disease is a chronic debilitating enteropathy of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP). Current abattoir surveillance programs detect disease via examination of gross lesions and confirmation by histopathological and/or tissue culture, which is time-consuming and has relatively low sensitivity. This study aimed to investigate whether a high-throughput quantitative PCR (qPCR) test is a viable alternative for tissue testing. Intestine and mesenteric lymph nodes were sourced from sheep experimentally infected with MAP and the DNA extracted using a protocol developed for tissues, comprised enzymatic digestion of the tissue homogenate, chemical and mechanical lysis, and magnetic bead-based DNA purification. The extracted DNA was tested by adapting a previously validated qPCR for fecal samples, and the results were compared with culture and histopathology results of the corresponding tissues. The MAP tissue qPCR confirmed infection in the majority of sheep with gross lesions on postmortem (37/38). Likewise, almost all tissue culture (61/64) or histopathology (52/58) positives were detected with good to moderate agreement (Cohen's kappa statistic) and no significant difference to the reference tests (McNemar's Chi-square test). Higher MAP DNA quantities corresponded to animals with more severe histopathology (odds ratio: 1.82; 95% confidence interval: 1.60, 2.07). Culture-independent strain typing on tissue DNA was successfully performed. This MAP tissue qPCR method had a sensitivity equivalent to the reference tests and is thus a viable replacement for gross- and histopathological examination of tissue samples in abattoirs. In addition, the test could be validated for testing tissue samples intended for human consumption.

Low-Cost energy contraption design using playground seesaw

NASA Astrophysics Data System (ADS)

Banlawe, I. A. P.; Acosta, N. J. E. L.

2017-05-01

The study was conducted at Western Philippines University, San Juan, Aborlan, Palawan. The study used the mechanical motion of playground seesaw as a means to produce electrical energy. The study aimed to design a low-cost prototype energy contraption using playground seesaw using locally available and recycled materials, to measure the voltage, current and power outputs produced at different situations and estimate the cost of the prototype. Using principle of pneumatics, two hand air pumps were employed on the two end sides of the playground seesaw and the mechanical motion of the seesaw up and down produces air that is used to rotate a DC motor to produce electrical energy. This electricity can be utilized for powering basic or low-power appliances. There were two trials of testing, each trial tests the different pressure level of the air tank and tests the opening of on-off valve (Full open and half open) when the compressed air was released. Results showed that all pressure level at full open produced significantly higher voltage, than the half open. However, the mean values of the current and power produced in all pressure level at full and half open have negligible variation. These results signify that the energy contraption using playground seesaw is an alternative viable source of electrical energy in the playgrounds, parks and other places and can be used as an auxiliary or back-up source for electricity.

Forensic DNA typing from teeth using demineralized root tips.

PubMed

Corrêa, Heitor Simões Dutra; Pedro, Fabio Luis Miranda; Volpato, Luiz Evaristo Ricci; Pereira, Thiago Machado; Siebert Filho, Gilberto; Borges, Álvaro Henrique

2017-11-01

Teeth are widely used samples in forensic human genetic identification due to their persistence and practical sampling and processing. Their processing, however, has changed very little in the last 20 years, usually including powdering or pulverization of the tooth. The objective of this study was to present demineralized root tips as DNA sources while, at the same time, not involving powdering the samples or expensive equipment for teeth processing. One to five teeth from each of 20 unidentified human bodies recovered from midwest Brazil were analyzed. Whole teeth were demineralized in EDTA solution with daily solution change. After a maximum of approximately seven days, the final millimeters of the root tip was excised. This portion of the sample was used for DNA extraction through a conventional organic protocol. DNA quantification and STR amplification were performed using commercial kits followed by capillary electrophoresis on 3130 or 3500 genetic analyzers. For 60% of the unidentified bodies (12 of 20), a full genetic profile was obtained from the extraction of the first root tip. By the end of the analyses, full genetic profiles were obtained for 85% of the individuals studied, of which 80% were positively identified. This alternative low-tech approach for postmortem teeth processing is capable of extracting DNA in sufficient quantity and quality for forensic casework, showing that root tips are viable nuclear DNA sources even after demineralization. Copyright © 2017 Elsevier B.V. All rights reserved.

Investigating Elevated Concentrations of Hydrogen in the LAX region

NASA Astrophysics Data System (ADS)

Rund, P.; Hughes, S.; Blake, D. R.

2017-12-01

The growing interest in hydrogen (H2) fuel cell vehicles has created a need to study the atmospheric H2 budget. While there is resounding agreement that hydrogen would escape into the atmosphere due to fuel transport/storage processes, there is disagreement over the amount that would be leaked in a hydrogen fuel economy. Leakage rate estimates range from 2% to 10% for total hydrogen production and transport. A hydrogen based energy infrastructure seems a viable clean alternative to oil because, theoretically, the only waste products are H2O and heat. However, hydrogen leads to the formation of water vapor, polar stratospheric clouds, and a decrease in stratospheric temperatures, which contribute to the depletion of stratospheric ozone. Whole air samples (WAS) collected aboard the NASA Sherpa C-23 during the Student Airborne Research Program (SARP) showed elevated concentrations of hydrogen near LAX (950 ± 110 ppbv) compared to global average concentrations of 560 ± 20 ppbv. Trace gas analysis along with wind trajectories obtained with the NOAA HySPLIT models indicate that the source of elevated mixing ratios was leakage from H2 fuel stations in the surrounding areas. Correlation and ratio analyses eliminate the potential for common photochemical sources of H2 in the LAX area. This project could elucidate new and potential factors that contribute to the global atmospheric hydrogen budget.

Thermal plasma technology for the treatment of wastes: a critical review.

PubMed

Gomez, E; Rani, D Amutha; Cheeseman, C R; Deegan, D; Wise, M; Boccaccini, A R

2009-01-30

This review describes the current status of waste treatment using thermal plasma technology. A comprehensive analysis of the available scientific and technical literature on waste plasma treatment is presented, including the treatment of a variety of hazardous wastes, such as residues from municipal solid waste incineration, slag and dust from steel production, asbestos-containing wastes, health care wastes and organic liquid wastes. The principles of thermal plasma generation and the technologies available are outlined, together with potential applications for plasma vitrified products. There have been continued advances in the application of plasma technology for waste treatment, and this is now a viable alternative to other potential treatment/disposal options. Regulatory, economic and socio-political drivers are promoting adoption of advanced thermal conversion techniques such as thermal plasma technology and these are expected to become increasingly commercially viable in the future.

Senior health clinics: are they financially viable?

PubMed

McAtee, Robin E; Crandall, Debra; Wright, Larry D; Beverly, Claudia J

2009-07-01

Are hospital-based outpatient interdisciplinary clinics a financially viable alternative for caring for our burgeoning population of older adults in America? Although highly popular, with high patient satisfaction rates among older adults and their families, senior health clinics (SHCs) can be expensive to operate, with limited quantifiable health outcomes. This study analyzed three geriatric hospital-based interdisciplinary clinics in rural Arkansas by examining their patient profiles, revenues, and expenses. It closely examined the effects of the downstream revenue using the multiplier effect and acknowledged other factors that weigh heavily on the success of SHCs and the care of older adults. The findings highlight the similarities and differences in the three clinics' operating and financial structures in addition to the clinics' and providers' productivity. The analysis presents an evidence-based illustration that SHCs can break even or lose large amounts of money.