Sample records for visa entry form

  1. 75 FR 4901 - 60-Day Notice of Proposed Information Collection: DS-5501, Electronic Diversity Visa Entry Form...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ...-5501, Electronic Diversity Visa Entry Form, OMB Control Number 1405-0153 ACTION: Notice of request for... Visa Entry Form. OMB Control Number: 1405-0153. Type of Request: Extension of currently approved collection. Originating Office: Bureau of Consular Affairs, Office of Visa Services (CA/VO). Form Number: DS...

  2. 75 FR 25024 - 30-Day Notice of Proposed Information Collection: DS-5501, Electronic Diversity Visa Entry Form...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-06

    ...-5501, Electronic Diversity Visa Entry Form, OMB Control Number 1405-0153 ACTION: Notice of request for... Collection: Electronic Diversity Visa Entry Form. OMB Control Number: 1405-0153. Type of Request: Extension of Currently Approved Collection. Originating Office: Bureau of Consular Affairs, Office of Visa...

  3. 78 FR 41971 - 30-Day Notice of Proposed Information Collection: Electronic Diversity Visa Entry Form

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ...: Electronic Diversity Visa Entry Form ACTION: Notice of request for public comment and submission to OMB of... collection instrument and supporting documents, to Sydney Taylor, Visa Services, U.S. [[Page [email protected] SUPPLEMENTARY INFORMATION: Title of Information Collection: Electronic Diversity Visa...

  4. 78 FR 12132 - 60-Day Notice of Proposed Information Collection: Electronic Diversity Visa Entry Form

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ...: Electronic Diversity Visa Entry Form ACTION: Notice of request for public comment. SUMMARY: The Department of... page. Email: [email protected] . Mail: Chief, Legislation and Regulations Division, Visa... Taylor, Visa Services, U.S. Department of State, 2401 E Street NW., L-603, Washington, DC 20522, who may...

  5. 75 FR 7151 - 60-Day Notice of Proposed Information Collection: DS-5501, Electronic Diversity Visa Entry Form...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-17

    ... DEPARTMENT OF STATE [Public Notice: 6888] 60[dash]Day Notice of Proposed Information Collection: DS-5501, Electronic Diversity Visa Entry Form, OMB Control Number 1405-0153 Correction In notice document 2010-1863 appearing on page 4901 in the issue of January 29, 2010, make the following correction...

  6. Ministerial Ordinance No. 530/166 of 10 July 1989, establishing measures to execute Decree-Law No. 1/007 of 20 March 1989 setting forth regulations on the entry, stay, and establishment of foreigners in Burundi and their departure.

    PubMed

    1989-01-01

    This Ordinance sets forth rules on visas, identity cards, and monetary guarantees as established in Decree-Law No. 1/007 of 20 March 1989. Visas can be granted for the purposes of transit, entry, stay, departure and return, and establishment of both determined and indeterminate length. A transit visa permits a foreigner to enter Burundi for not more than seventy-two hours; an entry visa allows a foreigner to make one or more entries into Burundi and stay there for a period of not more than three months; a visa of stay is given to a foreigner who already has a transit or entry visa and allows that person to lengthen his visit for up to six months; a visa of departure and return is granted to foreigners residing in Burundi who wish to return to Burundi after travelling abroad and is good for up to seven months; a visa of establishment of determinate length is granted to a person who wishes to become established in Burundi and whose proposed activity has already been approved; a visa of establishment of indeterminate length is granted to a foreigner who has resided in Burundi for the uninterrupted period of the preceding twenty years, although exceptions are possible, as in the case of persons who marry Burundi citizens. In order to receive an identity card, a foreigner must be registered in the community of his residence within fifteen days of obtaining a visa of establishment or permission to change his residence. Identity cards are given to six groups of foreigners: permanent residents, persons who hold visas of establishment of either determinate or indeterminate nature, diplomats, refugees, and the stateless. All persons authorized to establish themselves in Burundi are required to deposit a monetary guarantee in the amount of $1,250 US.

  7. 8 CFR 215.9 - Temporary Worker Visa Exit Program.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Temporary Worker Visa Exit Program. 215.9... ALIENS DEPARTING FROM THE UNITED STATES § 215.9 Temporary Worker Visa Exit Program. An alien admitted on certain temporary worker visas at a port of entry participating in the Temporary Worker Visa Exit Program...

  8. 8 CFR 215.9 - Temporary Worker Visa Exit Program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Temporary Worker Visa Exit Program. 215.9... ALIENS DEPARTING FROM THE UNITED STATES § 215.9 Temporary Worker Visa Exit Program. An alien admitted on certain temporary worker visas at a port of entry participating in the Temporary Worker Visa Exit Program...

  9. 8 CFR 215.9 - Temporary Worker Visa Exit Program.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Temporary Worker Visa Exit Program. 215.9... ALIENS DEPARTING FROM THE UNITED STATES § 215.9 Temporary Worker Visa Exit Program. An alien admitted on certain temporary worker visas at a port of entry participating in the Temporary Worker Visa Exit Program...

  10. 8 CFR 215.9 - Temporary Worker Visa Exit Program.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Temporary Worker Visa Exit Program. 215.9... ALIENS DEPARTING FROM THE UNITED STATES § 215.9 Temporary Worker Visa Exit Program. An alien admitted on certain temporary worker visas at a port of entry participating in the Temporary Worker Visa Exit Program...

  11. 8 CFR 215.9 - Temporary Worker Visa Exit Program.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Temporary Worker Visa Exit Program. 215.9... ALIENS DEPARTING FROM THE UNITED STATES § 215.9 Temporary Worker Visa Exit Program. An alien admitted on certain temporary worker visas at a port of entry participating in the Temporary Worker Visa Exit Program...

  12. 8 CFR 286.9 - Fee for processing applications and issuing documentation at land border Ports-of-Entry.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .../Departure Record, for admission at a land border Port-of-Entry must remit the required fee for issuance of... Card, issued by the DOS, or a passport and combined B-1/B-2 visa and non-biometric BCC (or similar stamp in a passport) issued by the DOS, who is required to be issued Form I-94, Arrival/Departure Record...

  13. 8 CFR 286.9 - Fee for processing applications and issuing documentation at land border Ports-of-Entry.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .../Departure Record, for admission at a land border Port-of-Entry must remit the required fee for issuance of... Card, issued by the DOS, or a passport and combined B-1/B-2 visa and non-biometric BCC (or similar stamp in a passport) issued by the DOS, who is required to be issued Form I-94, Arrival/Departure Record...

  14. 8 CFR 286.9 - Fee for processing applications and issuing documentation at land border Ports-of-Entry.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...), Arrival/Departure Record, for admission at a land border Port-of-Entry must remit the required fee for... Card, issued by the DOS, or a passport and combined B-1/B-2 visa and non-biometric BCC (or similar stamp in a passport) issued by the DOS, who is required to be issued Form I-94, Arrival/Departure Record...

  15. 8 CFR 286.9 - Fee for processing applications and issuing documentation at land border Ports-of-Entry.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .../Departure Record, for admission at a land border Port-of-Entry must remit the required fee for issuance of... Card, issued by the DOS, or a passport and combined B-1/B-2 visa and non-biometric BCC (or similar stamp in a passport) issued by the DOS, who is required to be issued Form I-94, Arrival/Departure Record...

  16. 8 CFR 286.9 - Fee for processing applications and issuing documentation at land border Ports-of-Entry.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .../Departure Record, for admission at a land border Port-of-Entry must remit the required fee for issuance of... Card, issued by the DOS, or a passport and combined B-1/B-2 visa and non-biometric BCC (or similar stamp in a passport) issued by the DOS, who is required to be issued Form I-94, Arrival/Departure Record...

  17. 8 CFR 101.2 - Presumption of lawful admission; entry under erroneous name or other errors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... concealing his identity when obtaining a passport or visa, or for the purpose of using the passport or visa... making application for a passport or visa to have permitted the issuing authority or authorities to have...

  18. 8 CFR 101.2 - Presumption of lawful admission; entry under erroneous name or other errors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... concealing his identity when obtaining a passport or visa, or for the purpose of using the passport or visa... making application for a passport or visa to have permitted the issuing authority or authorities to have...

  19. 8 CFR 101.2 - Presumption of lawful admission; entry under erroneous name or other errors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... concealing his identity when obtaining a passport or visa, or for the purpose of using the passport or visa... making application for a passport or visa to have permitted the issuing authority or authorities to have...

  20. 8 CFR 101.2 - Presumption of lawful admission; entry under erroneous name or other errors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... concealing his identity when obtaining a passport or visa, or for the purpose of using the passport or visa... making application for a passport or visa to have permitted the issuing authority or authorities to have...

  1. 8 CFR 101.2 - Presumption of lawful admission; entry under erroneous name or other errors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... concealing his identity when obtaining a passport or visa, or for the purpose of using the passport or visa... making application for a passport or visa to have permitted the issuing authority or authorities to have...

  2. 8 CFR 1101.2 - Presumption of lawful admission; entry under erroneous name or other errors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the purpose of concealing his identity when obtaining a passport or visa, or for the purpose of using the passport or visa of another person or otherwise evading any provision of the immigration laws, and... time prior to making application for a passport or visa to have permitted the issuing authority or...

  3. 8 CFR 1101.2 - Presumption of lawful admission; entry under erroneous name or other errors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the purpose of concealing his identity when obtaining a passport or visa, or for the purpose of using the passport or visa of another person or otherwise evading any provision of the immigration laws, and... time prior to making application for a passport or visa to have permitted the issuing authority or...

  4. 8 CFR 1101.2 - Presumption of lawful admission; entry under erroneous name or other errors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the purpose of concealing his identity when obtaining a passport or visa, or for the purpose of using the passport or visa of another person or otherwise evading any provision of the immigration laws, and... time prior to making application for a passport or visa to have permitted the issuing authority or...

  5. 8 CFR 1101.2 - Presumption of lawful admission; entry under erroneous name or other errors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the purpose of concealing his identity when obtaining a passport or visa, or for the purpose of using the passport or visa of another person or otherwise evading any provision of the immigration laws, and... time prior to making application for a passport or visa to have permitted the issuing authority or...

  6. 8 CFR 1101.2 - Presumption of lawful admission; entry under erroneous name or other errors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the purpose of concealing his identity when obtaining a passport or visa, or for the purpose of using the passport or visa of another person or otherwise evading any provision of the immigration laws, and... time prior to making application for a passport or visa to have permitted the issuing authority or...

  7. Ordinance No. 054/PRG/SGG/87 on conditions of entry and stay in the Republic of Guinea, 22 July 1987.

    PubMed

    1989-01-01

    An ordinance passed on July 22, 1987, governs the entry and residence of foreigners in Guinea. Passports are required for everyone but citizens of Guinea, and entry visas are necessary unless a person is in transit on a ship or airplane or is a citizen of a country which has a reciprocity agreement with Guinea. The entry visa, which is valid for 3 months, is gained by submitting a written request, proof of financial means, a return ticket or security deposit, and 2 photographs. The request may be granted or denies without explanation. Further entry requirements are a valid medical certificate and, if employed in Guinea, an approved employment contract. A transit visa is required of foreigners staying for no more than 5 days, unless they stay n areas designated by competent authorities. A temporary stay visa (renewable once) is required for foreigners who are staying from 5-90 days; they, like all foreigners in Guinea, must have a return ticket or means to leave. Foreigners who wish to stay in Guinea after expiration of their 90-day visa (except accompanied minors, citizens of certain countries, and diplomats) must obtain an extended stay visa, a residence permit, and an allied card. Experts working for the government of Guinea on a longterm basis need an expert resident identity card. Foreigners who wish to reside in Guinea must obtain a foreign resident card or alien card. Refugees and stateless persons must acquire a political refugee or stateless person identification card. To obtain a residence permit, foreigners must have entered Guinea, legally, paid visa and permit taxes, and have an extended stay visa, a certificate of recent physical examination, a work permit, and an employment contract. This permit may be renewed or replaced if lost. An alien card must be obtained by foreigners over the age of fifteen who work in Guinea and want to establish residence; this is issued after the foreigner has paid a tax and gotten an extended stay visa. Foreigners are permitted to move freely in the country, except in places designated by policy or security forces. Holders of alien cards or work permits must notify authorities if they change their address. Landlords, in turn, must notify authorities if they have foreigners as tenants. A foreign resident care and work permit are required in order to secure employment. In general, travelers and temporary residents are not allowed to hold a job. Employers who hire a foreigner must notify the National Employment Office and Immigration authorities. A foreigner's stay may be terminated by public authorities at any time. Those who help a foreigner enter, move through, or stay in the country illegally can be punished.

  8. 77 FR 30045 - 60-Day Notice of Proposed Information Collection: Supplemental Registration for the Diversity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ...-Day Notice of Proposed Information Collection: Supplemental Registration for the Diversity Immigrant... of Information Collection: Supplemental Registration for the Diversity Immigrant Visa Program. OMB... register the randomly selected entries and send the applicants an Instruction Package for Immigrant Visa...

  9. 48 CFR 752.7023 - Required visa form for USAID participants.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Required visa form for... Clauses 752.7023 Required visa form for USAID participants. For use in any USAID direct contract which involves training of USAID participants. Required Visa Form for USAID Participants (APR 1984) The...

  10. 48 CFR 752.7023 - Required visa form for USAID participants.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Required visa form for... Clauses 752.7023 Required visa form for USAID participants. For use in any USAID direct contract which involves training of USAID participants. Required Visa Form for USAID Participants (APR 1984) The...

  11. 48 CFR 752.7023 - Required visa form for USAID participants.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Required visa form for... Clauses 752.7023 Required visa form for USAID participants. For use in any USAID direct contract which involves training of USAID participants. Required Visa Form for USAID Participants (APR 1984) The...

  12. 48 CFR 752.7023 - Required visa form for USAID participants.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Required visa form for... Clauses 752.7023 Required visa form for USAID participants. For use in any USAID direct contract which involves training of USAID participants. Required Visa Form for USAID Participants (APR 1984) The...

  13. 48 CFR 752.7023 - Required visa form for USAID participants.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Required visa form for... Clauses 752.7023 Required visa form for USAID participants. For use in any USAID direct contract which involves training of USAID participants. Required Visa Form for USAID Participants (APR 1984) The...

  14. Interministerial Circular, 2 June 1988.

    PubMed

    1988-01-01

    The text of this Circular on resolving the question of Vietnamese citizens wanting to leave the country to join their families or for other humanitarian reasons is as follows: "1) Those Vietnamese citizens applying for exit visas to resettle abroad must complete all procedures established by the Ministry of Interior. The Ministry of the Interior is responsible for considering and solving applications for exit visas and for notifying the applicants of the results. It must issue exit visas and do other paperwork for those Vietnamese citizens applying for exit visas. 2) The Foreign Affairs Ministry is responsible for cooperating with immigrant-accepting countries and other relevant international organizations in solving entry procedures for those already approved by the interior ministry for leaving the country." full text

  15. Multimodal biometric digital watermarking on immigrant visas for homeland security

    NASA Astrophysics Data System (ADS)

    Sasi, Sreela; Tamhane, Kirti C.; Rajappa, Mahesh B.

    2004-08-01

    Passengers with immigrant Visa's are a major concern to the International Airports due to the various fraud operations identified. To curb tampering of genuine Visa, the Visa's should contain human identification information. Biometric characteristic is a common and reliable way to authenticate the identity of an individual [1]. A Multimodal Biometric Human Identification System (MBHIS) that integrates iris code, DNA fingerprint, and the passport number on the Visa photograph using digital watermarking scheme is presented. Digital Watermarking technique is well suited for any system requiring high security [2]. Ophthalmologists [3], [4], [5] suggested that iris scan is an accurate and nonintrusive optical fingerprint. DNA sequence can be used as a genetic barcode [6], [7]. While issuing Visa at the US consulates, the DNA sequence isolated from saliva, the iris code and passport number shall be digitally watermarked in the Visa photograph. This information is also recorded in the 'immigrant database'. A 'forward watermarking phase' combines a 2-D DWT transformed digital photograph with the personal identification information. A 'detection phase' extracts the watermarked information from this VISA photograph at the port of entry, from which iris code can be used for identification and DNA biometric for authentication, if an anomaly arises.

  16. 77 FR 6137 - Agency Information Collection Activities: Guam-CNMI Visa Waiver Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... Activities: Guam-CNMI Visa Waiver Agreement AGENCY: U.S. Customs and Border Protection, Department of... comment on an information collection requirement concerning the Guam-CNMI Visa Waiver Agreement (CBP Form... information collection: Title: Guam-CNMI Visa Waiver Agreement. OMB Number: 1651-0126. Form Number: CBP Form I...

  17. 77 FR 32711 - 30-Day Notice of Proposed Information Collection: DS-234, Special Immigrant Visa Biodata Form...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ..., Special Immigrant Visa Biodata Form, OMB Number 1405-0203 ACTION: Notice of request for public comment and... of Information Collection: Special Immigrant Visa Biodata Form. OMB Control Number: 1405-0203. Type... Special Immigrant Visa Applicants. Estimated Number of Respondents: 12,000 per year. Estimated Number of...

  18. 77 FR 19304 - Agency Information Collection Activities: Guam-CNMI Visa Waiver Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ... Activities: Guam-CNMI Visa Waiver Information AGENCY: U.S. Customs and Border Protection (CBP), Department of... requirement concerning the Guam-CNMI Visa Waiver Information (CBP Form I-736). This request for comment is...: Title: Guam-CNMI Visa Waiver Information. OMB Number: 1651-0109. Form Number: CBP Form I-736. Abstract...

  19. 78 FR 19726 - Agency Information Collection Activities: Visa Waiver Program Carrier Agreement (CBP Form I-775)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-02

    ... Activities: Visa Waiver Program Carrier Agreement (CBP Form I-775) AGENCY: U.S. Customs and Border Protection... information collection requirement concerning the Visa Waiver Program Carrier Agreement (CBP Form I-775). This... concerning the following information collection: Title: Visa Waiver Program Carrier Agreement. OMB Number...

  20. 76 FR 62494 - 30-Day Notice of Proposed Information Collection: DS-157, Supplemental Nonimmigrant Visa Form...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-07

    ..., Supplemental Nonimmigrant Visa Form, OMB Control Number 1405-0134 ACTION: Notice of request for public comment...: Supplemental Nonimmigrant Visa Application. OMB Control Number: 1405-0134. Type of Request: Extension of a...). Form Number: DS-157. Respondents: Nonimmigrant visa applicants legally required to provide additional...

  1. 75 FR 5099 - Agency Information Collection Activities: Visa Waiver Program Carrier Agreement (Form I-775)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-01

    ... Activities: Visa Waiver Program Carrier Agreement (Form I-775) AGENCY: U.S. Customs and Border Protection... and Budget (OMB) for review and approval in accordance with the Paperwork Reduction Act: Visa Waiver... other technological techniques or other forms of information. Title: Visa Waiver Program Carrier...

  2. 8 CFR 211.3 - Expiration of immigrant visas, reentry permits, refugee travel documents, and Form I-551.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Expiration of immigrant visas, reentry... Expiration of immigrant visas, reentry permits, refugee travel documents, and Form I-551. An immigrant visa... holder embarked or enplaned before the expiration of his or her immigrant visa, reentry permit, or...

  3. 22 CFR 42.63 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.63 Definitions. (a) Application forms—(1) Application on Form DS-230 or Form DS-260 required. Every alien applying for an immigrant visa must make...

  4. 22 CFR 42.63 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.63 Definitions. (a) Application forms—(1) Application on Form DS-230 or Form DS-260 required. Every alien applying for an immigrant visa must make...

  5. 22 CFR 42.63 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.63 Definitions. (a) Application forms—(1) Application on Form DS-230 or Form DS-260 required. Every alien applying for an immigrant visa must make...

  6. 22 CFR 42.63 - Application forms and other documentation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....63 Section 42.63 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.63 Application... alien applying for an immigrant visa must make application on Form DS-230, Application for Immigrant...

  7. 22 CFR 42.63 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.63 Definitions. (a) Application forms—(1) Application on Form DS-230 or Form DS-260 Required.—Every alien applying for an immigrant visa must make...

  8. 8 CFR 211.3 - Expiration of immigrant visas, reentry permits, refugee travel documents, and Form I-551.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Expiration of immigrant visas, reentry... OF HOMELAND SECURITY IMMIGRATION REGULATIONS DOCUMENTARY REQUIREMENTS: IMMIGRANTS; WAIVERS § 211.3 Expiration of immigrant visas, reentry permits, refugee travel documents, and Form I-551. An immigrant visa...

  9. Migration Amendment Act 1987 (No. 133 of 1987), 16 December 1987.

    PubMed

    1988-01-01

    This Act does the following, among other things: 1) requires that certain requests relating to entry permits, visas, and return endorsements are not considered to have been made unless in writing in accordance with the relevant approved forms and unless any fee payable has been made; 2) makes "operators," as well as charterers, liable for the carriage of persons to Australia without documentation; and 3) provides that international air operators shall pay immigration clearance fees payable by passengers whether or not the operator has collected the fees from the passengers. full text

  10. 75 FR 25909 - 60-Day Notice of Proposed Information Collection: Form DS-156K, Nonimmigrant Fiancé(e) Visa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-10

    ...-156K, Nonimmigrant Fianc[eacute](e) Visa Application, OMB Control Number 1405-0096 ACTION: Notice of...: Nonimmigrant Fianc[eacute](e) Visa Application. OMB Control Number: 1405-0096. Type of Request: Extension of a... State (CA/VO). Form Number: DS-156K. Respondents: Aliens applying for a nonimmigrant visa to enter the U...

  11. 75 FR 54690 - 60-Day Notice of Proposed Information Collection: DS-160, Online Application for Nonimmigrant Visa

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... Collection: DS-160, Online Application for Nonimmigrant Visa ACTION: Notice of request for public comments... Nonimmigrant Visa. OMB Control Number: 1405-0182. Type of Request: Revision. Originating Office: Bureau of Consular Affairs, Visa Services (CA/VO). Form Number: DS-160. Respondents: All nonimmigrant visa applicants...

  12. Using fingerprint image quality to improve the identification performance of the U.S. Visitor and Immigrant Status Indicator Technology Program

    PubMed Central

    Wein, Lawrence M.; Baveja, Manas

    2005-01-01

    Motivated by the difficulty of biometric systems to correctly match fingerprints with poor image quality, we formulate and solve a game-theoretic formulation of the identification problem in two settings: U.S. visa applicants are checked against a list of visa holders to detect visa fraud, and visitors entering the U.S. are checked against a watchlist of criminals and suspected terrorists. For three types of biometric strategies, we solve the game in which the U.S. Government chooses the strategy's optimal parameter values to maximize the detection probability subject to a constraint on the mean biometric processing time per legal visitor, and then the terrorist chooses the image quality to minimize the detection probability. At current inspector staffing levels at ports of entry, our model predicts that a quality-dependent two-finger strategy achieves a detection probability of 0.733, compared to 0.526 under the quality-independent two-finger strategy that is currently implemented at the U.S. border. Increasing the staffing level of inspectors offers only minor increases in the detection probability for these two strategies. Using more than two fingers to match visitors with poor image quality allows a detection probability of 0.949 under current staffing levels, but may require major changes to the current U.S. biometric program. The detection probabilities during visa application are ≈11–22% smaller than at ports of entry for all three strategies, but the same qualitative conclusions hold. PMID:15894628

  13. Using fingerprint image quality to improve the identification performance of the U.S. Visitor and Immigrant Status Indicator Technology Program.

    PubMed

    Wein, Lawrence M; Baveja, Manas

    2005-05-24

    Motivated by the difficulty of biometric systems to correctly match fingerprints with poor image quality, we formulate and solve a game-theoretic formulation of the identification problem in two settings: U.S. visa applicants are checked against a list of visa holders to detect visa fraud, and visitors entering the U.S. are checked against a watchlist of criminals and suspected terrorists. For three types of biometric strategies, we solve the game in which the U.S. Government chooses the strategy's optimal parameter values to maximize the detection probability subject to a constraint on the mean biometric processing time per legal visitor, and then the terrorist chooses the image quality to minimize the detection probability. At current inspector staffing levels at ports of entry, our model predicts that a quality-dependent two-finger strategy achieves a detection probability of 0.733, compared to 0.526 under the quality-independent two-finger strategy that is currently implemented at the U.S. border. Increasing the staffing level of inspectors offers only minor increases in the detection probability for these two strategies. Using more than two fingers to match visitors with poor image quality allows a detection probability of 0.949 under current staffing levels, but may require major changes to the current U.S. biometric program. The detection probabilities during visa application are approximately 11-22% smaller than at ports of entry for all three strategies, but the same qualitative conclusions hold.

  14. 75 FR 35119 - 60-Day Notice of Proposed Information Collection: Form DS-4085 Application for Additional Visa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ... DS-4085 Application for Additional Visa Pages or Miscellaneous Passport Services, OMB Control Number... of Information Collection: Application for Additional Visa Pages or Miscellaneous Passport Services.... Originating Office: Bureau of Consular Affairs, Passport Services CA/PPT. Form Number: DS-4085. Respondents...

  15. 75 FR 66412 - 60-Day Notice of Proposed Information Collection: DS-156, Nonimmigrant Visa Application, OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-28

    ..., Nonimmigrant Visa Application, OMB Control Number 1405-0018 ACTION: Notice of request for public comments... the Paperwork Reduction Act of 1995. Title of Information Collection: Nonimmigrant Visa Application.... Originating Office: Bureau of Consular Affairs (CA/VO). Form Number: DS-156. Respondents: Nonimmigrant visa...

  16. 76 FR 10082 - 60-Day Notice of Proposed Information Collection: DS-157, Supplemental Nonimmigrant Visa Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ... Information Collection: DS-157, Supplemental Nonimmigrant Visa Application ACTION: Notice of request for...: Supplemental Nonimmigrant Visa Application. OMB Control Number: 1405-0134. Type of Request: Extension of a...). Form Number: DS-157. Respondents: Nonimmigrant visa applicants legally required to provide additional...

  17. 77 FR 34056 - Agency Information Collection Activities: Guam-CNMI Visa Waiver Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... Activities: Guam-CNMI Visa Waiver Information AGENCY: U.S. Customs and Border Protection, Department of... review and approval in accordance with the Paperwork Reduction Act: Guam-CNMI Visa Waiver Information... techniques or other forms of information. Title: Guam-CNMI Visa Waiver Information. OMB Number: 1651-0109...

  18. 77 FR 6167 - 30-Day Notice of Proposed Information Collection: DS-230, Application for Immigrant Visa and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ..., Application for Immigrant Visa and Alien Registration, OMB Number 1405- 0015 ACTION: Notice of request for... Collection: Application for Immigrant Visa and Alien Registration. OMB Control Number: 1405-0015. Type of... Form DS-230 (Application for Immigrant Visa and Alien Registration), in conjunction with a personal...

  19. 8 CFR 211.1 - Visas.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Visas. 211.1 Section 211.1 Aliens and...; WAIVERS § 211.1 Visas. (a) General. Except as provided in paragraph (b)(1) of this section, each arriving..., unexpired immigrant visa; (2) A valid, unexpired Form I-551, Permanent Resident Card, if seeking readmission...

  20. 8 CFR 211.1 - Visas.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Visas. 211.1 Section 211.1 Aliens and...; WAIVERS § 211.1 Visas. (a) General. Except as provided in paragraph (b)(1) of this section, each arriving..., unexpired immigrant visa; (2) A valid, unexpired Form I-551, Permanent Resident Card, if seeking readmission...

  1. 76 FR 20070 - 30-Day Notice of Proposed Information Collection: DS-156, Nonimmigrant Visa Application, OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    ..., Nonimmigrant Visa Application, OMB Control Number 1405-0018 ACTION: Notice of request for public comment and... accordance with the Paperwork Reduction Act of 1995. Title of Information Collection: Nonimmigrant Visa.... Originating Office: Bureau of Consular Affairs (CA/VO). Form Number: DS-156. Respondents: Nonimmigrant visa...

  2. 78 FR 77771 - 60-Day Notice of Proposed Information Collection: Nonimmigrant Visa Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ...: Nonimmigrant Visa Application ACTION: Notice of request for public comment. SUMMARY: The Department of State is...: Nonimmigrant Visa Application OMB Control Number: 1405-0018 Type of Request: Extension of Currently Approved Collection Originating Office: CA/VO/L/R Form Number: DS-156 Respondents: All Nonimmigrant Visa Applicants...

  3. 8 CFR 211.1 - Visas.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Visas. 211.1 Section 211.1 Aliens and...; WAIVERS § 211.1 Visas. (a) General. Except as provided in paragraph (b)(1) of this section, each arriving..., unexpired immigrant visa; (2) A valid, unexpired Form I-551, Permanent Resident Card, if seeking readmission...

  4. 8 CFR 211.1 - Visas.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Visas. 211.1 Section 211.1 Aliens and...; WAIVERS § 211.1 Visas. (a) General. Except as provided in paragraph (b)(1) of this section, each arriving..., unexpired immigrant visa; (2) A valid, unexpired Form I-551, Permanent Resident Card, if seeking readmission...

  5. 75 FR 77935 - 30-Day Notice of Proposed Information Collection: DS-160, Online Application for Nonimmigrant...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-14

    ..., Online Application for Nonimmigrant Visa, OMB 1405-0182 ACTION: Notice of request for public comment and... Nonimmigrant Visa. OMB Control Number: 1405-0182. Type of Request: Revision. Originating Office: Bureau of Consular Affairs, Visa Services (CA/VO). Form Number: DS-160. Respondents: All nonimmigrant visa applicants...

  6. 76 FR 35506 - 30-Day Notice of Proposed Information Collection: DS-3035, J-1 Visa Waiver Recommendation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ..., J-1 Visa Waiver Recommendation Application ACTION: Notice of request for public comment and... accordance with the Paperwork Reduction Act of 1995. Title of Information Collection: J-1 Visa Waiver...). Form Number: DS-3035. Respondents: J-1 visa holders applying for a waiver of the two-year foreign...

  7. 75 FR 25910 - 60-Day Notice of Proposed Information Collection: DS-1648, Application for A, G, or NATO Visa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-10

    ...-1648, Application for A, G, or NATO Visa, OMB No. 1405-0100 ACTION: Notice of request for public... NATO Visa. OMB Control Number: 1405-0100. Type of Request: Revision of a Currently Approved Collection. Originating Office: Bureau of Consular Affairs, Office of Visa Services. Form Number: DS-1648. Respondents...

  8. 75 FR 57543 - 30-Day Notice of Proposed Information Collection: DS-1648, Application for A, G, or NATO Visa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ...-1648, Application for A, G, or NATO Visa, OMB No. 1405-0100 ACTION: Notice of request for public...: Application for A, G, or NATO Visa. OMB Control Number: 1405-0100. Type of Request: Revision of a Currently Approved Collection. Originating Office: Bureau of Consular Affairs, Office of Visa Services. Form Number...

  9. 75 FR 57543 - 30-Day Notice of Proposed Information Collection: Form DS-156K, Nonimmigrant Fiance(e) Visa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... DS-156K, Nonimmigrant Fiance(e) Visa Application, OMB Control Number 1405-0096 ACTION: Notice of... Reduction Act of 1995. Title of Information Collection: Nonimmigrant Fiance(e) Visa Application. OMB Control... applying for a nonimmigrant visa to enter the U.S. as the fianc[eacute](e) of a U.S. citizen Estimated...

  10. 8 CFR 211.1 - Visas.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS DOCUMENTARY REQUIREMENTS: IMMIGRANTS..., unexpired immigrant visa; (2) A valid, unexpired Form I-551, Permanent Resident Card, if seeking readmission... issuance of an immigrant visa to his or her accompanying parent who applies for admission during the...

  11. 77 FR 3486 - Agency Information Collection Activities: No Agency Form Number, File Number OMB 25, Extension of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-24

    ..., Special Immigrant Visas for Fourth Preference Employment-Based Broadcasters; OMB Control No. 1615-0064... the Form/Collection: Special Immigrant Visas for Fourth Preference Employment-Based Broadcasters. (3...

  12. 75 FR 45475 - Visas: Documentation of Immigrants Under the Immigration and Nationality Act, as Amended

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    ... alien registration, to offer a completely electronic application procedure as an alternative to submission of Form DS-230, the Application for Immigrant Visa and Alien Registration. DATES: This rule is..., Application for Immigrant Visa and Alien Registration. While the Department will continue to accept the DS-230...

  13. 77 FR 71668 - 30-Day Notice of Proposed Information Collection: Choice of Address and Agent for Immigrant Visa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-03

    ... of Address and Agent for Immigrant Visa Applicants AGENCY: Department of State. ACTION: Notice of... Agent for Immigrant Visa Applicants. OMB Control Number: 1405-0126. Type of Request: Extension of Currently Approved Collection. Originating Office: CA/VO/L/R. Form Number: DS-3032. Respondents: Immigrant...

  14. 22 CFR 42.67 - Execution of application, registration, and fingerprinting.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.67...) Application fee. A fee is prescribed for each application for an immigrant visa. It shall be collected prior... applicant shall be required to read the Form DS-230, Application for Immigrant Visa and Alien Registration...

  15. 77 FR 65439 - 30-Day Notice of Proposed Information Collection: Supplemental Registration for the Diversity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ...: Supplemental Registration for the Diversity Immigrant Visa Program ACTION: Notice of request for public comment... for the Diversity Immigrant Visa Program. OMB Control Number: 1405-0098. Type of Request: Extension... applicants an Instruction Package for Immigrant Visa Applicants, which consists of Form DS-122 (Supplemental...

  16. 76 FR 26750 - Agency Information Collection Activities: New Information Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-09

    ... collection under review: Visa Processing Fee Payment; OMB control No. 1615-New. The Department of Homeland... . When submitting comments by e-mail please make sure to add Visa Processing Fee Payment in the subject...: Visa Processing Fee Payment. (3) Agency form number, if any, and the applicable component of the...

  17. Heat shock cognate 71 (HSC71) regulates cellular antiviral response by impairing formation of VISA aggregates.

    PubMed

    Liu, Zhigang; Wu, Shu-Wen; Lei, Cao-Qi; Zhou, Qian; Li, Shu; Shu, Hong-Bing; Wang, Yan-Yi

    2013-05-01

    In response to viral infection, RIG-I-like RNA helicases detect viral RNA and signal through the mitochondrial adapter protein VISA. VISA activation leads to rapid activation of transcription factors IRF3 and NF-κB, which collaborate to induce transcription of type I interferon (IFN) genes and cellular antiviral response. It has been demonstrated that VISA is activated by forming prion-like aggregates. However, how this process is regulated remains unknown. Here we show that overexpression of HSC71 resulted in potent inhibition of virus-triggered transcription of IFNB1 gene and cellular antiviral response. Consistently, knockdown of HSC71 had opposite effects. HSC71 interacted with VISA, and negatively regulated virus-triggered VISA aggregation. These findings suggest that HSC71 functions as a check against VISA-mediated antiviral response.

  18. 77 FR 23317 - 60-Day Notice of Proposed Information Collection: DS-3032 Choice of Address and Agent for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ... Choice of Address and Agent for Immigrant Visa Applicants, 1405-0126 ACTION: Notice of request for public... for Immigrant Visa Applicants. OMB Control Number: 1405-0126. Type of Request: Extension. Originating Office: CA/VO/L/R. Form Number: DS-3032. Respondents: Immigrant Visa Applicants. Estimated Number of...

  19. 77 FR 59692 - 2014 Diversity Immigrant Visa Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... the E-DV system. The entry will not be accepted and must be resubmitted. Group or family photographs... must be in the Joint Photographic Experts Group (JPEG) format. Image File Size: The maximum file size...). Image File Format: The image must be in the Joint Photographic Experts Group (JPEG) format. Image File...

  20. 75 FR 62915 - 30-Day Notice of Proposed Information Collection: Form DS-4085, Application for Additional Visa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-13

    ...-4085, Application for Additional Visa Pages or Miscellaneous Passport Services, OMB Control Number 1405... Passport Services. OMB Control Number: 1405-0159. Type of Request: Revision of a Currently Approved Collection. Originating Office: Bureau of Consular Affairs, Passport Services CA/PPT. Form Number: DS-4085...

  1. "Slow VISA," a novel phenotype of vancomycin resistance, found in vitro in heterogeneous vancomycin-intermediate Staphylococcus aureus strain Mu3.

    PubMed

    Saito, Michie; Katayama, Yuki; Hishinuma, Tomomi; Iwamoto, Akira; Aiba, Yoshifumi; Kuwahara-Arai, Kyoko; Cui, Longzhu; Matsuo, Miki; Aritaka, Nanae; Hiramatsu, Keiichi

    2014-09-01

    Heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) clinical strain Mu3 spontaneously generates VISA strains at an extremely high frequency (≥1×10(-6)). The generated VISA strains usually grow more slowly than does the parent hVISA strain, but they form colonies on vancomycin-containing agar plates before 48 h of incubation. However, we noticed a curious group of VISA strains, designated "slow VISA" (sVISA), whose colonies appear only after 72 h of incubation. They have extremely prolonged doubling times but have vancomycin MICs of 8 to ∼24 mg/liter when determined after 72 to ∼144 h of incubation. We established strain Mu3-6R-P (6R-P), which has a vancomycin MIC of 16 mg/liter (at 72 h), as a representative sVISA strain. Its cell wall was thickened and autolytic activity was decreased compared to the respective qualities of the parent hVISA strain Mu3. Whole-genome sequencing of 6R-P revealed only one mutation, encoded by rpoB (R512P), which replaced the 512th arginine of the RNA polymerase β-subunit with proline. Its VISA phenotype was unstable, and the strain frequently reverted to hVISA with concomitant losses of pinpoint colony morphology and cell wall thickness and reduced autolytic activity. Sequencing of the rpoB genes of the phenotypic revertant strains revealed mutations affecting the 512th codon, where the proline of 6R-P was replaced with leucine, serine, or histidine. Slow VISA generated in the tissues of an infected patient serves as a temporary shelter for hVISA to survive vancomycin therapy. The sVISA strain spontaneously returns to hVISA when the threat of vancomycin is lifted. The rpoB(R512P) mutation may be regarded as a regulatory mutation that switches the reversible phenotype of sVISA on and off. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  2. Nonimmigrant Overstays: Brief Synthesis of the Issue

    DTIC Science & Technology

    2010-01-15

    finger biometric system for immigration identification17 to the major identity management and screening... finger scans and digital photographs) to check identity. Enhanced Border Security and Visa Entry Reform Act of 2002 The Enhanced Border Security ...further provides: “A determination by the Secretary of Homeland Security that an alien who applied for authorization to travel to the United States

  3. “Slow VISA,” a Novel Phenotype of Vancomycin Resistance, Found In Vitro in Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Strain Mu3

    PubMed Central

    Saito, Michie; Katayama, Yuki; Hishinuma, Tomomi; Iwamoto, Akira; Aiba, Yoshifumi; Kuwahara-Arai, Kyoko; Cui, Longzhu; Matsuo, Miki; Aritaka, Nanae

    2014-01-01

    Heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) clinical strain Mu3 spontaneously generates VISA strains at an extremely high frequency (≥1 × 10−6). The generated VISA strains usually grow more slowly than does the parent hVISA strain, but they form colonies on vancomycin-containing agar plates before 48 h of incubation. However, we noticed a curious group of VISA strains, designated “slow VISA” (sVISA), whose colonies appear only after 72 h of incubation. They have extremely prolonged doubling times but have vancomycin MICs of 8 to ∼24 mg/liter when determined after 72 to ∼144 h of incubation. We established strain Mu3-6R-P (6R-P), which has a vancomycin MIC of 16 mg/liter (at 72 h), as a representative sVISA strain. Its cell wall was thickened and autolytic activity was decreased compared to the respective qualities of the parent hVISA strain Mu3. Whole-genome sequencing of 6R-P revealed only one mutation, encoded by rpoB (R512P), which replaced the 512th arginine of the RNA polymerase β-subunit with proline. Its VISA phenotype was unstable, and the strain frequently reverted to hVISA with concomitant losses of pinpoint colony morphology and cell wall thickness and reduced autolytic activity. Sequencing of the rpoB genes of the phenotypic revertant strains revealed mutations affecting the 512th codon, where the proline of 6R-P was replaced with leucine, serine, or histidine. Slow VISA generated in the tissues of an infected patient serves as a temporary shelter for hVISA to survive vancomycin therapy. The sVISA strain spontaneously returns to hVISA when the threat of vancomycin is lifted. The rpoB(R512P) mutation may be regarded as a regulatory mutation that switches the reversible phenotype of sVISA on and off. PMID:24841271

  4. 76 FR 39385 - Payment Policy Change for Access to NOAA Environmental Data, Information, and Related Products...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-06

    ... accepted forms of payment are Visa, MasterCard, American Express, Discover, wire transfers and Automated.... currency, by VISA, MasterCard, American Express, and Discover. Cardholder's name, charge card number...

  5. HAUS8 regulates RLR‑VISA antiviral signaling positively by targeting VISA.

    PubMed

    He, Tian-Sheng; Chen, Tian; Wang, Dan-Dan; Xu, Liang-Guo

    2018-06-15

    Mitochondrial anti‑viral signaling protein (VISA), additionally termed MAVS, IPS‑1 and Cardif, is located at the outer membrane of mitochondria and is an essential adaptor in the Rig‑like receptor (RLRs) signaling pathway. Upon viral infection, activated RLRs interact with VISA on mitochondria, forming a RLR‑VISA platform, leading to the recruitment of different TRAF family members, including TRAF3, TRAF2 and TRAF6. This results in the phosphorylation and nuclear translocation of interferon regulatory factors 3 and 7 (IRF3/IRF7) by TANK binding kinase 1 (TBK1) and/or IKKε, as well as activation of NF‑κB, to induce type I interferons (IFNs) and pro‑inflammatory cytokines. It remains to be elucidated how VISA functions as a scaffold for protein complex assembly in mitochondria to regulate RLR‑VISA antiviral signaling. In the present study, it was demonstrated that HAUS augmin like complex subunit 8 (HAUS8) augments the RLR‑VISA‑dependent antiviral signaling pathway by targeting the VISA complex. Co‑immunoprecipitation verified that HAUS8 was associated with VISA and the VISA signaling complex components retinoic acid‑inducible gene I (RIG‑I) and TBK1 when the RLR‑VISA signaling pathway was activated. The data demonstrated that overexpression of HAUS8 significantly promoted the activity of the transcription factors NF‑κB, IRF3 and the IFN‑β promoter induced by Sendai virus‑mediated RLR‑VISA signaling. HAUS8 increased the polyubiquitination of VISA, RIG‑I and TBK1. Knockdown of HAUS8 inhibited the activation of the transcription factors IRF‑3, NF‑κB and the IFN‑β promoter triggered by Sendai virus. Collectively, these results demonstrated that HAUS8 may function as a positive regulator of RLR‑VISA dependent antiviral signaling by targeting the VISA complex, providing a novel regulatory mechanism of antiviral responses.

  6. 8 CFR 1212.10 - Section 212(k) waiver.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Section 212(k) waiver. 1212.10 Section 1212... § 1212.10 Section 212(k) waiver. Any applicant for admission who is in possession of an immigrant visa... director at the port of entry for a waiver under section 212(k) of the Act. If the application for waiver...

  7. 8 CFR 1212.10 - Section 212(k) waiver.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Section 212(k) waiver. 1212.10 Section 1212... § 1212.10 Section 212(k) waiver. Any applicant for admission who is in possession of an immigrant visa... director at the port of entry for a waiver under section 212(k) of the Act. If the application for waiver...

  8. 8 CFR 1212.10 - Section 212(k) waiver.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Section 212(k) waiver. 1212.10 Section 1212... § 1212.10 Section 212(k) waiver. Any applicant for admission who is in possession of an immigrant visa... director at the port of entry for a waiver under section 212(k) of the Act. If the application for waiver...

  9. 8 CFR 1212.10 - Section 212(k) waiver.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Section 212(k) waiver. 1212.10 Section 1212... § 1212.10 Section 212(k) waiver. Any applicant for admission who is in possession of an immigrant visa... director at the port of entry for a waiver under section 212(k) of the Act. If the application for waiver...

  10. 8 CFR 1212.10 - Section 212(k) waiver.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Section 212(k) waiver. 1212.10 Section 1212... § 1212.10 Section 212(k) waiver. Any applicant for admission who is in possession of an immigrant visa... director at the port of entry for a waiver under section 212(k) of the Act. If the application for waiver...

  11. 77 FR 1777 - 60-Day Notice of Proposed Information Collection: DS-261, Electronic Choice of Address and Agent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ... Consular Affairs, Visa Services (CA/VO/L/R). Form Number: DS-261. Respondents: Immigrant beneficiaries... immigrant visa petition to provide the Department with his current address, which will be used for...

  12. 76 FR 17426 - Agency Information Collection Activities: Application for Waiver of Passport and/or Visa (Form I...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-29

    ... submitted will be summarized and included in the CBP request for Office of Management and Budget (OMB... wish to waive the documentary requirements for passports and/or visas due to an unforeseen emergency...

  13. 75 FR 13293 - Agency Information Collection Activities: Arrival and Departure Record

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    ...), the Form I-94W (Nonimmigrant Visa Waiver Arrival/Departure), and the Electronic System for Travel... Act (Pub. L.104-13). Your comments should address one of the following four points: (1) Evaluate..., Nonimmigrant Visa Waiver Arrival/Departure, Electronic System for Travel Authorization (ESTA) OMB Number: 1651...

  14. 75 FR 70017 - Agency Information Collection Activities: File Number OMB 25, Extension of a Currently Approved...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ... Request ACTION: 30-Day Notice of Information Collection Under Review: OMB 25, Special Immigrant Visas for...) Title of the Form/Collection: Special Immigrant Visas for Fourth Preference Employment-Based... for the requested classification as fourth preference Employment-based immigrant broadcasters. (5) An...

  15. 75 FR 52540 - Agency Information Collection Activities: File Number OMB 25; Extension of an Existing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-26

    .... ACTION: 60-Day Notice of Information Collection Under Review: OMB 25, Special Immigrant Visas for Fourth.../Collection: Special Immigrant Visas for Fourth Preference Employment-Based Broadcasters. (3) Agency form... preference Employment-based immigrant broadcasters. (5) An estimate of the total number of respondents and...

  16. 8 CFR 217.6 - Carrier agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Carrier agreements. 217.6 Section 217.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS VISA WAIVER PROGRAM § 217... shall be made by the Commissioner on behalf of the Attorney General and shall be on Form I-775, Visa...

  17. 77 FR 28921 - 30-Day Notice of Proposed Information Collection: DS-260, Electronic Application for Immigration...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ..., Electronic Application for Immigration Visa and Alien Registration, 1405-0185 ACTION: Notice of request for... Collection: Electronic Application for Immigration Visa and Alien Registration. OMB Control Number: 1405-0185... collection: Form DS-260 will be used to elicit information to determine the eligibility of aliens applying...

  18. 8 CFR 212.6 - Border crossing identification cards.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... or pleasure without a visa and passport, must apply to the DOS on Form DS-156, Visitor Visa... border crossing card (or similar stamp in a passport). (i) A Canadian citizen or other person sharing... crossing card (or similar stamp in a passport) issued by the DOS prior to April 1, 1998, that does not...

  19. 8 CFR 212.6 - Border crossing identification cards.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... or pleasure without a visa and passport, must apply to the DOS on Form DS-156, Visitor Visa... border crossing card (or similar stamp in a passport). (i) A Canadian citizen or other person sharing... crossing card (or similar stamp in a passport) issued by the DOS prior to April 1, 1998, that does not...

  20. 8 CFR 212.6 - Border crossing identification cards.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... or pleasure without a visa and passport, must apply to the DOS on Form DS-156, Visitor Visa... border crossing card (or similar stamp in a passport). (i) A Canadian citizen or other person sharing... crossing card (or similar stamp in a passport) issued by the DOS prior to April 1, 1998, that does not...

  1. 8 CFR 212.6 - Border crossing identification cards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... or pleasure without a visa and passport, must apply to the DOS on Form DS-156, Visitor Visa... border crossing card (or similar stamp in a passport). (i) A Canadian citizen or other person sharing... crossing card (or similar stamp in a passport) issued by the DOS prior to April 1, 1998, that does not...

  2. 8 CFR 212.6 - Border crossing identification cards.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... or pleasure without a visa and passport, must apply to the DOS on Form DS-156, Visitor Visa... border crossing card (or similar stamp in a passport). (i) A Canadian citizen or other person sharing... crossing card (or similar stamp in a passport) issued by the DOS prior to April 1, 1998, that does not...

  3. Development and validation of a new visa questionnaire (VISA-H) for patients with proximal hamstring tendinopathy.

    PubMed

    Cacchio, Angelo; De Paulis, Fosco; Maffulli, Nicola

    2014-03-01

    There is a need for a patient-reported outcome (PRO) questionnaire to evaluate patients with proximal hamstring tendinopathy (PHT). To develop a PRO questionnaire based on VISA questionnaire forms for patients with PHT. Item generation, item reduction, item scaling and evaluation of the psychometric properties were used to develop a questionnaire to assess the severity of symptoms, function and ability to play sports in patients with PHT and healthy subjects. The final version, named Victorian Institute of Sport Assessment-Proximal Hamstring Tendons (VISA-H), consisted of eight questions that measured the domains of pain, function and sporting activity. The psychometric properties of a questionnaire were estimated in a population of non-surgical (n=20) and surgical (n=10) patients, as well as in healthy subjects (n=30). The VISA-H questionnaire displayed a high degree of internal consistency, with a Cronbach α of 0.84. (The test-retest reliability was high for all groups of participants with an intraclass correlation coefficient ranging from 0.90 to 0.95.) The VISA-H exhibited a high correlation with the Nirschl phase rating scale (r ranging from -0.75 to -0.89) and a generic tendon grading system proposed by Curwin and Stanish (r ranging from -0.70 to -0.88). Also, the responsiveness was higher for the VISA-H questionnaire with an area under the curve of 0.90 and a minimum clinically important difference of 22 points. The VISA-H is a PRO questionnaire with high psychometric properties for measuring pain, function and sporting activity in patients with PHT.

  4. Al Qaeda and Affiliates: Historical Perspective, Global Presence, and Implications for U.S. Policy

    DTIC Science & Technology

    2010-02-05

    mountainous tribal belt of northwest Pakistan, where it continues to train operatives, recruit, and disseminate propaganda. But Al Qaeda franchises or...April 2005 to U.S. charges of involvement in the September 11 plot, apparently visited Malaysia and met with cell members in 2000. Additionally, the...Qaeda leader, Malaysia was viewed as an ideal location for transiting and meeting because it allowed visa-free entry to citizens of most Gulf states

  5. THE MINIMUM CLINICALLY IMPORTANT DIFFERENCE ON THE VISA-A AND LEFS FOR PATIENTS WITH INSERTIONAL ACHILLES TENDINOPATHY.

    PubMed

    McCormack, Joshua; Underwood, Frank; Slaven, Emily; Cappaert, Thomas

    2015-10-01

    Cohort study of subjects with insertional Achilles tendinopathy (IAT). The purpose of this study was to establish the minimum clinically important difference (MCID) on the Victorian Institute of Sport Assessment - Achilles Questionnaire (VISA-A) and the Lower Extremity Functional Scale (LEFS) for patients with IAT. The VISA-A and LEFS are two measures commonly utilized for patients with IAT. Previous authors have estimated the MCID for the VISA-A, but a MCID has not been formally established. The MCID for the LEFS has been established for patients with lower extremity conditions in general, but it is not clear if this MCID is applicable to patients with IAT. Fifteen subjects participating in a randomized controlled trial studying the effectiveness of intervention for IAT over a 12-week period were included in this study. Subjects completed the VISA-A and LEFS forms at baseline and 12 weeks after the initiation of treatment. All subjects also completed a 15-point global rating of change (GROC) questionnaire at 12 weeks after the initiation of treatment. Subjects were classified as improved or stable based on their GROC scores. The area under the curve (AUC) for the VISA-A was 0.97 and a MCID of 6.5 points was identified. The AUC for the LEFS was 0.97 and a MCID of 12 points was identified. The VISA-A and LEFS are both useful outcome measures to assess response in patients with IAT. 3.

  6. Cross-cultural Adaptation and Validation of the Victorian Institute of Sport Assessment-Patella Questionnaire for French-Speaking Patients With Patellar Tendinopathy.

    PubMed

    Kaux, Jean-François; Delvaux, François; Oppong-Kyei, Julian; Beaudart, Charlotte; Buckinx, Fanny; Croisier, Jean-Louis; Forthomme, Bénédicte; Crielaard, Jean-Michel; Bruyère, Olivier

    2016-05-01

    Study Design Clinical measurement study. Background The Victorian Institute of Sport Assessment-Patella (VISA-P), originally developed in English, assesses the severity of patellar tendinopathy symptoms. To date, no French version of the questionnaire exists. Objectives The aim of our study was to translate the VISA-P into French and verify its psychometric properties. Methods The translation and cultural adaptation were performed according to international recommendations in 6 steps: initial translation, translation merging, back translation to the original language, use of an expert committee to reach a prefinal version, test of the prefinal version, and expert committee appraisal of a final version. Afterward, the psychometric properties of the final French version (VISA-PF) were assessed in 92 subjects, divided into 3 groups: pathological subjects (n = 28), asymptomatic subjects (n = 22), and sports-risk subjects (n = 42). Results All members of the expert committee agreed with the final version. On a scale ranging from 0 to 100, with 100 representing an asymptomatic subject, the average ± SD scores on the VISA-PF were 53 ± 17 for the pathological group, 99 ± 2 for the healthy group, and 86 ± 14 for the sports-risk group. The test-retest reliability of the VISA-PF was excellent, with good internal consistency. Correlations between the VISA-PF and divergent validity of the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) were low, and the correlation coefficient values measured between the VISA-PF scores and converged items of the SF-36 were higher. Conclusion The VISA-PF is understandable, valid, and suitable for French-speaking patients with patellar tendinopathy. J Orthop Sports Phys Ther 2016;46(5):384-390. Epub 21 Mar 2016. doi:10.2519/jospt.2016.5937.

  7. Immigration policy and internationally educated nurses in the United States: A brief history

    PubMed Central

    Masselink, Leah E.; Jones, Cheryl B.

    2015-01-01

    Since the 1980s, U.S. policy makers have used immigration policy to influence the supply of nurses by allowing or restricting the entry of internationally educated nurses (IENs) into the U.S. workforce. The methods pursued have shifted over time from temporary visa categories in the 1980s and 1990s to permanent immigrant visas in the 2000s. The impact of policy measures adopted during nursing shortages has often been blunted by political and economic events, but the number and representation of IENs in the U.S. nursing workforce has increased substantially since the 1980s. Even as the United States seeks to increase domestic production of nurses, it remains a desirable destination for IENs and a target market for nurse-producing source countries. Hiring organizations and nurse leaders play a critical role in ensuring that the hiring and integration of IENs into U.S. health care organizations is constructive for nurses, source countries, and the U.S. health care system. PMID:24345614

  8. Uneven Hedging of Economic Risks for a Skilled Workforce: Are Immigrants Disadvantaged?

    PubMed Central

    Hao, Lingxin; Warkentien, Siri

    2015-01-01

    Skilled immigration to the United States has been multi-channeled via legislations on permanent and temporary visa programs. This paper argues that skilled immigrants were not disadvantaged during the Great Recession because of a new hedging mechanism, which starts with the federal legislations that admit skilled nonimmigrants, proceeds to vest authority in employers, who perform rigorous screening and selection of temporary workers for future permanency, and ends with greater protection of those selected. To test this mechanism, the paper examines skilled immigrants’ spatial mobility out of the country and their domestic labor market outcomes. The paper presents evidence from analyzing repeated, nationally representative survey data of college graduates in the US using demographic techniques of intra-cohort and inter-cohort analyses. The major findings about the substantial cross-border mobility and high levels of labor force participation among at-entry temporary visa holders who later gained permanent residency provide strong evidence to support our proposed new hedging mechanism. PMID:27605891

  9. Decree No. 1991, Regulations to the Law on Foreigners, 30 June 1986.

    PubMed

    1988-01-01

    Among other things, these Regulations set forth rules on requirements for visas established in the Ecuador Law on Foreigners. They list the amounts of income from abroad or investments in Ecuador required of foreigners entering Ecuador with immigrant visas, documents needed by persons working permanently in enterprises and institutions under immigrant visas, and methods of proof of dependency for persons entering on immigrant visas as dependents. In this context, they provide that persons with foreign income must receive at least $1,000 per month, with an increase of 80% Ecuadorian personnel; that persons entering as workers must inform authorities of changes in work status; and that persons entering as dependents may themselves work only if their sponsor dies or the means of subsistence of the sponsor decrease. The Regulations also set forth requirements for persons entering Ecuador on nonimmigrant visas, such as refugees, students, temporary workers, religious personnel, and those in transit. With respect to refugees, the rules provide that false statements made in an application will trigger an expulsion order; that foreign nationals coming from a country other than that where they suffered persecution will not be admitted unless they were in that country in direct transit; that refugees may not leave the country without express permission; and that, if the conditions justifying asylum change, a refugee will be required to leave the country. With respect to workers, the rules provide that an applicant must show a need for a foreign worker that cannot be fulfilled by an Ecuadorian worker and must show a work contract or appointment. With respect to those in transit, the rules provide that no visa is required and that entry will be denied to those lacking permission to enter the country of destination and transit through countries bordering Ecuador that are on their route. Persons in this category may stay in Ecuador for only a limited time--usually 10 days for persons en route and three months for visitors. The Regulations also contain provisions on the modification of immigration status, including the rule that the status of those in transit may not be modified. In addition, they set forth the functions of the Consultative Council on Migration Policy. Among these is the task of promoting internal migration to sparsely populated areas of the country. full text

  10. Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase activation recruitment domain.

    PubMed

    Potter, Jane A; Randall, Richard E; Taylor, Garry L

    2008-02-28

    IPS-1/MAVS/VISA/Cardif is an adaptor protein that plays a crucial role in the induction of interferons in response to viral infection. In the initial stage of the intracellular antiviral response two RNA helicases, retinoic acid inducible gene-I (RIG-I) and melanoma differentiation-association gene 5 (MDA5), are independently able to bind viral RNA in the cytoplasm. The 62 kDa protein IPS-1/MAVS/VISA/Cardif contains an N-terminal caspase activation and recruitment (CARD) domain that associates with the CARD regions of RIG-I and MDA5, ultimately leading to the induction of type I interferons. As a first step towards understanding the molecular basis of this important adaptor protein we have undertaken structural studies of the IPS-1 MAVS/VISA/Cardif CARD region. The crystal structure of human IPS-1/MAVS/VISA/Cardif CARD has been determined to 2.1A resolution. The protein was expressed and crystallized as a maltose-binding protein (MBP) fusion protein. The MBP and IPS-1 components each form a distinct domain within the structure. IPS-1/MAVS/VISA/Cardif CARD adopts a characteristic six-helix bundle with a Greek-key topology and, in common with a number of other known CARD structures, contains two major polar surfaces on opposite sides of the molecule. One face has a surface-exposed, disordered tryptophan residue that may explain the poor solubility of untagged expression constructs. The IPS-1/MAVS/VISA/Cardif CARD domain adopts the classic CARD fold with an asymmetric surface charge distribution that is typical of CARD domains involved in homotypic protein-protein interactions. The location of the two polar areas on IPS-1/MAVS/VISA/Cardif CARD suggest possible types of associations that this domain makes with the two CARD domains of MDA5 or RIG-I. The N-terminal CARD domains of RIG-I and MDA5 share greatest sequence similarity with IPS-1/MAVS/VISA/Cardif CARD and this has allowed modelling of their structures. These models show a very different charge profile for the equivalent surfaces compared to IPS-1/MAVS/VISA/Cardif CARD.

  11. 22 CFR 42.71 - Authority to issue visas; visa fees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 42.71 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.71 Authority to issue visas; visa fees. (a) Authority to issue visas. Consular officers may issue immigrant visas at designated consular...

  12. 22 CFR 42.71 - Authority to issue visas; visa fees.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Authority to issue visas; visa fees. 42.71 Section 42.71 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.71 Authority to issue visas; visa...

  13. 22 CFR 42.71 - Authority to issue visas; visa fees.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Authority to issue visas; visa fees. 42.71 Section 42.71 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.71 Authority to issue visas; visa...

  14. 22 CFR 42.71 - Authority to issue visas; visa fees.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Authority to issue visas; visa fees. 42.71 Section 42.71 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.71 Authority to issue visas; visa...

  15. 22 CFR 42.71 - Authority to issue visas; visa fees.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Authority to issue visas; visa fees. 42.71 Section 42.71 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.71 Authority to issue visas; visa...

  16. Cross-cultural adaptation of VISA-P score for patellar tendinopathy in Spanish population.

    PubMed

    Hernandez-Sanchez, Sergio; Hidalgo, Maria Dolores; Gomez, Antonia

    2011-08-01

    Clinical measurement. To adapt the VISA-P questionnaire into Spanish and to assess its psychometric properties. Health status questionnaires and scales to report outcomes are increasingly used in medical research and clinical practice. Validated versions of these tools are necessary to avoid bias during use in different languages and cultures. We followed international recommendations to perform cross-cultural adaptation. The Spanish VISA-P (VISA-P-Sp) questionnaire and the Short Form (36) Health Survey (SF-36) were administered to 150 individuals: 40 healthy students, 40 professional players in sports requiring jumping, 40 athletes with patellar tendinopathy, and 30 athletes with knee injuries other than patellar tendinopathy. Participants were assessed at baseline and after 1 week. Athletes with tendinopathy also completed questionnaires and other knee measures (the Kujala Scoring Questionnaire and the Cincinnati Knee Rating Scale) after physiotherapy treatment, which consisted of rest, ice, eccentric exercise, electrotherapy, and manual therapy. The VISA-P-Sp showed high reliability for both temporal stability (intraclass correlation coefficient [ICC] = 0.994; 95% CI: 0.992, 0.996) and internal consistency (Cronbach α = 0.885). Based on a factor analysis, a 2-factor solution explained 76.1% of the variance. The VISA-P-Sp score in the tendinopathy group was significantly correlated with scores on other knee scales (Kujala score [Spearman rho = 0.897; P<.001] and Cincinnati scale [Spearman rho = 0.782, P<.001]) and with SF-36 physical components score (Spearman rho>0.6, P<.001). The standardized size effect was 1.14, and the standardized response mean was 1.17. The VISA-P-Sp questionnaire proved to be a valid and reliable instrument, sensitive to clinical changes and comparable to the original English-language version.

  17. Cross-cultural Adaptation of the Victorian Institute of Sport Assessment-Achilles (VISA-A) Questionnaire for Spanish Athletes With Achilles Tendinopathy.

    PubMed

    Hernández-Sánchez, Sergio; Poveda-Pagán, Emilio José; Alakhdar-Mohmara, Yasser; Hidalgo, Maria Dolores; Fernández-de-Las-Peñas, César; Arias-Buría, José L

    2018-02-01

    Study Design Clinical measurement study. Background Achilles tendinopathy is a prevalent sport-related injury. The Victorian Institute of Sport Assessment-Achilles (VISA-A) questionnaire is a widely used patient-reported outcome to assess the severity of symptoms for this injury. Objective To adapt the VISA-A questionnaire into Spanish and to assess its psychometric properties. Methods Cross-cultural adaptation was conducted according to recommended guidelines. The Spanish VISA-A (VISA-A-Sp) questionnaire was administered to 210 subjects: 70 healthy students, 70 active at-risk subjects (participating in running and jumping), and 70 patients diagnosed with Achilles tendinopathy. Participants were assessed at baseline and after 3 to 5 days. The injured subjects were also evaluated with a quality-of-life questionnaire (Medical Outcomes Study 36-Item Short-Form Health Survey [SF-36]) and at discharge. The final VISA-A-Sp was evaluated for reliability, validity, and responsiveness. Results Cronbach alpha for the VISA-A-Sp was greater than .8. The intraclass correlation coefficient (model 2,1) was 0.993 (95% confidence interval: 0.991, 0.995; P<.05). In the confirmatory factor analysis, a 1-factor solution obtained a relatively good fit. Subjects with Achilles tendinopathy scored significantly lower than the other 2 groups (P<.001). The VISA-A-Sp score within the Achilles tendinopathy group showed significant correlations with SF-36 physical components (Spearman rho>0.5, P<.001). The standard error of the measurement was 2.53, and the minimal detectable change at the 95% confidence level was 7 points. The responsiveness indicators included an effect size of 2.16 and a standardized response mean of 1.92. Conclusion The VISA-A-Sp showed satisfactory psychometric properties that were comparable to the original English-language version. Therefore, it can be recommended for use in clinical practice and research for assessing the severity of symptoms in Spanish-speaking athletes who suffer from Achilles tendinopathy. J Orthop Sports Phys Ther 2018;48(2):111-120. Epub 13 Dec 2017. doi:10.2519/jospt.2018.7402.

  18. U.S. Citizenship and Immigration Services

    MedlinePlus

    ... Mail Order Forms by Phone "DS" Visa and Passport Forms (Department of State) I-94 Arrival/Departure ... Parents Exceptions and Accommodations Path to U.S. Citizenship Passports (Department of State) Citizenship for Military Personnel and ...

  19. 8 CFR 204.308 - Where to file Form I-800A or Form I-800.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204.308 Where to file Form I-800A or... adjudicate the child's application for an immigrant or nonimmigrant visa has jurisdiction to grant final...

  20. US refuses to issue entry visas to people with HIV / AIDS.

    PubMed

    1991-07-01

    The US government, ignoring the almost unanimous recommendation of medical and public health experts throughout the world, continues to ban both immigration and travel by people with HIV. Following recommendations from the US Centers for Disease Control and Prevention, the US Department of Health and Human Services indicated its intention to reduce the list of dangerous and contagious diseases for excluding entry to the US to include only active tuberculosis. That decision would have removed HIV/AIDS from the list. However, due to the subsequent 35,000 letters and postcards, mostly generated by conservative religious broadcasters and mailing houses opposed to lifting the ban, AIDS remained on the list. Opposition to lifting the ban came from the US Justice Department, as well as in the form of a signed statement to that end from 67 Republican members of the US Congress. US AIDS activists have organized their own letter campaign to support the removal of HIV/AIDS from the list. The June 1990 Sixth International Conference on AIDS was disrupted because of the travel ban. More than 70 AIDS, medical, and governmental organizations, including the International Red Cross, the British Medical Association, and the European Parliament boycotted the conferences. Planning for the 8th International Conference on AIDS, scheduled to be held in Boston in May 1992, is already being disputed and may not be held.

  1. Daptomycin non-susceptibility in vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous-VISA (hVISA): implications for therapy after vancomycin treatment failure.

    PubMed

    Kelley, Peter G; Gao, Wei; Ward, Peter B; Howden, Benjamin P

    2011-05-01

    The aim of this study was to establish the relationship between reduced vancomycin and daptomycin susceptibility among Australasian vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous-VISA (hVISA) isolates from patients never exposed to daptomycin. Forty-seven stored clinical isolates of hVISA/VISA collected before November 2008 from around Australia and New Zealand were selected. Daptomycin and vancomycin MIC testing was performed using broth microdilution (BMD) and Etest methods. Daptomycin population analysis was performed on a subset of isolates. The percentage of daptomycin non-susceptible isolates was 0% for vancomycin-susceptible S. aureus (VSSA) (Etest and BMD), for hVISA it was 26% by Etest and 15% by BMD, and for VISA 62% by Etest and 38% by BMD. Population analysis profile testing demonstrated daptomycin heteroresistance among the hVISA and VISA strains tested. This is the highest rate of daptomycin non-susceptibility reported among hVISA isolates to date. Clinicians should exhibit caution when using daptomycin in situations where serious hVISA or VISA infection is a possibility.

  2. Immigration policy and internationally educated nurses in the United States: A brief history.

    PubMed

    Masselink, Leah E; Jones, Cheryl B

    2014-01-01

    Since the 1980s, U.S. policy makers have used immigration policy to influence the supply of nurses by allowing or restricting the entry of internationally educated nurses (IENs) into the U.S. workforce. The methods pursued have shifted over time from temporary visa categories in the 1980s and 1990s to permanent immigrant visas in the 2000s. The impact of policy measures adopted during nursing shortages has often been blunted by political and economic events, but the number and representation of IENs in the U.S. nursing workforce has increased substantially since the 1980s. Even as the United States seeks to increase domestic production of nurses, it remains a desirable destination for IENs and a target market for nurse-producing source countries. Hiring organizations and nurse leaders play a critical role in ensuring that the hiring and integration of IENs into U.S. health care organizations is constructive for nurses, source countries, and the U.S. health care system. Copyright © 2014 Elsevier Inc. All rights reserved.

  3. 22 CFR 41.113 - Procedures in issuing visas.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... (a) Visa evidenced by stamp placed in passport. Except as provided in paragraphs (b) of this section, a nonimmigrant visa shall be evidenced by a visa stamp placed in the alien's passport. The... visa. (b) Cases in which visa not placed in passport. In the following cases the visa shall be placed...

  4. 22 CFR 41.113 - Procedures in issuing visas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... (a) Visa evidenced by stamp placed in passport. Except as provided in paragraphs (b) of this section, a nonimmigrant visa shall be evidenced by a visa stamp placed in the alien's passport. The... visa. (b) Cases in which visa not placed in passport. In the following cases the visa shall be placed...

  5. 22 CFR 41.113 - Procedures in issuing visas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... (a) Visa evidenced by stamp placed in passport. Except as provided in paragraphs (b) of this section, a nonimmigrant visa shall be evidenced by a visa stamp placed in the alien's passport. The... visa. (b) Cases in which visa not placed in passport. In the following cases the visa shall be placed...

  6. 22 CFR 41.113 - Procedures in issuing visas.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    .... (a) Visa evidenced by stamp placed in passport. Except as provided in paragraphs (b) of this section, a nonimmigrant visa shall be evidenced by a visa stamp placed in the alien's passport. The... visa. (b) Cases in which visa not placed in passport. In the following cases the visa shall be placed...

  7. 22 CFR 41.113 - Procedures in issuing visas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... (a) Visa evidenced by stamp placed in passport. Except as provided in paragraphs (b) of this section, a nonimmigrant visa shall be evidenced by a visa stamp placed in the alien's passport. The... visa. (b) Cases in which visa not placed in passport. In the following cases the visa shall be placed...

  8. Comprehensive identification of mutations responsible for heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA)-to-VISA conversion in laboratory-generated VISA strains derived from hVISA clinical strain Mu3.

    PubMed

    Matsuo, Miki; Cui, Longzhu; Kim, Jeeyoung; Hiramatsu, Keiichi

    2013-12-01

    Heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) spontaneously produces VISA cells within its cell population at a frequency of 10(-6) or greater. We established a total of 45 VISA mutant strains independently obtained from hVISA Mu3 and its related strains by one-step vancomycin selection. We then performed high-throughput whole-genome sequencing of the 45 strains and their parent strains to identify the genes involved in the hVISA-to-VISA phenotypic conversion. A comparative genome study showed that all the VISA strains tested carried a unique set of mutations. All of the 45 VISA strains carried 1 to 4 mutations possibly affecting the expression of a total of 48 genes. Among them, 32 VISA strains carried only one gene affected by a single mutation. As many as 20 genes in more than eight functional categories were affected in the 32 VISA strains, which explained the extremely high rates of the hVISA-to-VISA phenotypic conversion. Five genes, rpoB, rpoC, walK, pbp4, and pp2c, were previously reported as being involved in vancomycin resistance. Fifteen remaining genes were newly identified as associated with vancomycin resistance in this study. The gene most frequently affected (6 out of 32 strains) was cmk, which encodes cytidylate kinase, followed closely by rpoB (5 out of 32), encoding the β subunit of RNA polymerase. A mutation prevalence study also revealed a sizable number of cmk mutants among clinical VISA strains (7 out of 38 [18%]). Reduced cytidylate kinase activity in cmk mutant strains is proposed to contribute to the hVISA-to-VISA phenotype conversion by thickening the cell wall and reducing the cell growth rate.

  9. 22 CFR 42.72 - Validity of visas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.72 Validity of visas. (a) Period of validity. With the exception indicated herein, the period of validity of an immigrant visa shall not exceed six...

  10. 22 CFR 41.27 - Official visas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Official visas. 41.27 Section 41.27 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Foreign Government Officials § 41.27 Official visas. (a) Definition. Official visa...

  11. 22 CFR 41.27 - Official visas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Official visas. 41.27 Section 41.27 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Foreign Government Officials § 41.27 Official visas. (a) Definition. Official visa...

  12. 22 CFR 41.27 - Official visas.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Official visas. 41.27 Section 41.27 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Foreign Government Officials § 41.27 Official visas. (a) Definition. Official visa...

  13. 22 CFR 41.27 - Official visas.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Official visas. 41.27 Section 41.27 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Foreign Government Officials § 41.27 Official visas. (a) Definition. Official visa...

  14. 22 CFR 41.107 - Visa fees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Visa fees. 41.107 Section 41.107 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.107 Visa fees. (a) Fees based on...

  15. 22 CFR 41.107 - Visa fees.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Visa fees. 41.107 Section 41.107 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.107 Visa fees. (a) Fees based on...

  16. 22 CFR 41.107 - Visa fees.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Visa fees. 41.107 Section 41.107 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.107 Visa fees. (a) Fees based on...

  17. 22 CFR 41.107 - Visa fees.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Visa fees. 41.107 Section 41.107 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.107 Visa fees. (a) Fees based on...

  18. 22 CFR 41.107 - Visa fees.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Visa fees. 41.107 Section 41.107 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.107 Visa fees. (a) Fees based on...

  19. 22 CFR 41.27 - Official visas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Official visas. 41.27 Section 41.27 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Foreign Government Officials § 41.27 Official visas. (a) Definition. Official visa...

  20. Comprehensive Identification of Mutations Responsible for Heterogeneous Vancomycin-Intermediate Staphylococcus aureus (hVISA)-to-VISA Conversion in Laboratory-Generated VISA Strains Derived from hVISA Clinical Strain Mu3

    PubMed Central

    Matsuo, Miki; Cui, Longzhu; Kim, Jeeyoung

    2013-01-01

    Heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) spontaneously produces VISA cells within its cell population at a frequency of 10−6 or greater. We established a total of 45 VISA mutant strains independently obtained from hVISA Mu3 and its related strains by one-step vancomycin selection. We then performed high-throughput whole-genome sequencing of the 45 strains and their parent strains to identify the genes involved in the hVISA-to-VISA phenotypic conversion. A comparative genome study showed that all the VISA strains tested carried a unique set of mutations. All of the 45 VISA strains carried 1 to 4 mutations possibly affecting the expression of a total of 48 genes. Among them, 32 VISA strains carried only one gene affected by a single mutation. As many as 20 genes in more than eight functional categories were affected in the 32 VISA strains, which explained the extremely high rates of the hVISA-to-VISA phenotypic conversion. Five genes, rpoB, rpoC, walK, pbp4, and pp2c, were previously reported as being involved in vancomycin resistance. Fifteen remaining genes were newly identified as associated with vancomycin resistance in this study. The gene most frequently affected (6 out of 32 strains) was cmk, which encodes cytidylate kinase, followed closely by rpoB (5 out of 32), encoding the β subunit of RNA polymerase. A mutation prevalence study also revealed a sizable number of cmk mutants among clinical VISA strains (7 out of 38 [18%]). Reduced cytidylate kinase activity in cmk mutant strains is proposed to contribute to the hVISA-to-VISA phenotype conversion by thickening the cell wall and reducing the cell growth rate. PMID:24018261

  1. 22 CFR 42.73 - Procedure in issuing visas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.73 Procedure in issuing visas. (a) Insertion of data. In issuing an immigrant visa, the issuing office shall insert the pertinent information in the...

  2. 22 CFR 42.81 - Procedure in refusing individual visas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Procedure in refusing individual visas. 42.81 Section 42.81 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Procedure in refusing individual visas. (a) Issuance or refusal mandatory. When a visa application has been...

  3. 22 CFR 41.53 - Temporary workers and trainees.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 41.53 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.53 Temporary workers and trainees... alien is eligible to receive a nonimmigrant visa. (c) Validity of visa. The period of validity of a visa...

  4. 22 CFR 41.111 - Authority to issue visa.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Authority to issue visa. 41.111 Section 41.111 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Nonimmigrant Visa § 41.111 Authority to issue visa. (a...

  5. 22 CFR 41.112 - Validity of visa.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Validity of visa. 41.112 Section 41.112 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Nonimmigrant Visa § 41.112 Validity of visa. (a) Significance of...

  6. 22 CFR 41.112 - Validity of visa.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Validity of visa. 41.112 Section 41.112 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Nonimmigrant Visa § 41.112 Validity of visa. (a) Significance of...

  7. 22 CFR 42.81 - Procedure in refusing individual visas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Procedure in refusing individual visas. 42.81 Section 42.81 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Procedure in refusing individual visas. (a) Issuance or refusal mandatory. When a visa application has been...

  8. 22 CFR 41.112 - Validity of visa.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Validity of visa. 41.112 Section 41.112 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Nonimmigrant Visa § 41.112 Validity of visa. (a) Significance of...

  9. 22 CFR 42.72 - Validity of visas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Validity of visas. 42.72 Section 42.72 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.72 Validity of visas. (a) Period of validity. With...

  10. 22 CFR 41.53 - Temporary workers and trainees.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 41.53 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.53 Temporary workers and trainees... alien is eligible to receive a nonimmigrant visa. (c) Validity of visa. The period of validity of a visa...

  11. 22 CFR 41.111 - Authority to issue visa.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Authority to issue visa. 41.111 Section 41.111 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Nonimmigrant Visa § 41.111 Authority to issue visa. (a...

  12. 22 CFR 42.81 - Procedure in refusing individual visas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Procedure in refusing individual visas. 42.81 Section 42.81 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Procedure in refusing individual visas. (a) Issuance or refusal mandatory. When a visa application has been...

  13. 22 CFR 42.81 - Procedure in refusing individual visas.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Procedure in refusing individual visas. 42.81 Section 42.81 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Procedure in refusing individual visas. (a) Issuance or refusal mandatory. When a visa application has been...

  14. 22 CFR 42.72 - Validity of visas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Validity of visas. 42.72 Section 42.72 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.72 Validity of visas. (a) Period of validity. With...

  15. 22 CFR 41.111 - Authority to issue visa.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Authority to issue visa. 41.111 Section 41.111 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Nonimmigrant Visa § 41.111 Authority to issue visa. (a...

  16. 22 CFR 41.53 - Temporary workers and trainees.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 41.53 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.53 Temporary workers and trainees... alien is eligible to receive a nonimmigrant visa. (c) Validity of visa. The period of validity of a visa...

  17. 22 CFR 42.81 - Procedure in refusing individual visas.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Procedure in refusing individual visas. 42.81 Section 42.81 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Procedure in refusing individual visas. (a) Issuance or refusal mandatory. When a visa application has been...

  18. 22 CFR 41.53 - Temporary workers and trainees.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 41.53 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.53 Temporary workers and trainees... alien is eligible to receive a nonimmigrant visa. (c) Validity of visa. The period of validity of a visa...

  19. 22 CFR 41.112 - Validity of visa.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Validity of visa. 41.112 Section 41.112 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Nonimmigrant Visa § 41.112 Validity of visa. (a) Significance of...

  20. 22 CFR 42.72 - Validity of visas.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Validity of visas. 42.72 Section 42.72 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.72 Validity of visas. (a) Period of validity. With...

  1. 22 CFR 41.111 - Authority to issue visa.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Authority to issue visa. 41.111 Section 41.111 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Nonimmigrant Visa § 41.111 Authority to issue visa. (a...

  2. 22 CFR 41.111 - Authority to issue visa.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Authority to issue visa. 41.111 Section 41.111 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Nonimmigrant Visa § 41.111 Authority to issue visa. (a...

  3. 22 CFR 42.72 - Validity of visas.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Validity of visas. 42.72 Section 42.72 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.72 Validity of visas. (a) Period of validity. With...

  4. 22 CFR 41.112 - Validity of visa.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Validity of visa. 41.112 Section 41.112 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Nonimmigrant Visa § 41.112 Validity of visa. (a) Significance of...

  5. Modulating activity of vancomycin and daptomycin on the expression of autolysis cell-wall turnover and membrane charge genes in hVISA and VISA strains.

    PubMed

    Cafiso, Viviana; Bertuccio, Taschia; Spina, Daniela; Purrello, Simona; Campanile, Floriana; Di Pietro, Cinzia; Purrello, Michele; Stefani, Stefania

    2012-01-01

    Glycopeptides are still the gold standard to treat MRSA (Methicillin Resistant Staphylococcus aureus) infections, but their widespread use has led to vancomycin-reduced susceptibility [heterogeneous Vancomycin-Intermediate-Staphylococcus aureus (hVISA) and Vancomycin-Intermediate-Staphylococcus aureus (VISA)], in which different genetic loci (regulatory, autolytic, cell-wall turnover and cell-envelope positive charge genes) are involved. In addition, reduced susceptibility to vancomycin can influence the development of resistance to daptomycin. Although the phenotypic and molecular changes of hVISA/VISA have been the focus of different papers, the molecular mechanisms responsible for these different phenotypes and for the vancomycin and daptomycin cross-resistance are not clearly understood. The aim of our study was to investigate, by real time RT-PCR, the relative quantitative expression of genes involved in autolysis (atl-lytM), cell-wall turnover (sceD), membrane charges (mprF-dltA) and regulatory mechanisms (agr-locus-graRS-walKR), in hVISA and VISA cultured with or without vancomycin and daptomycin, in order to better understand the molecular basis of vancomycin-reduced susceptibility and the modulating activity of vancomycin and daptomycin on the expression of genes implicated in their reduced susceptibility mechanisms. Our results show that hVISA and VISA present common features that distinguish them from Vancomycin-Susceptible Staphylococcus aureus (VSSA), responsible for the intermediate glycopeptide resistance i.e. an increased cell-wall turnover, an increased positive cell-wall charge responsible for a repulsion mechanism towards vancomycin and daptomycin, and reduced agr-functionality. Indeed, VISA emerges from hVISA when VISA acquires a reduced autolysis caused by a down-regulation of autolysin genes, atl/lytM, and a reduction of the net negative cell-envelope charge via dltA over-expression. Vancomycin and daptomycin, acting in a similar manner in hVISA and VISA, can influence their cross-resistance mechanisms promoting VISA behavior in hVISA and enhancing the cell-wall pathways responsible for the intermediate vancomycin resistance in VISA. Daptomycin can also induce a charge repulsion mechanism both in hVISA and VISA increasing the activity of the mprF.

  6. 77 FR 21578 - Agency Information Collection Activities: Guam-CNMI Visa Waiver Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ... fine, pursuant to section 273 of the Immigration and Nationality Act (INA) (8 U.S.C. 1323), for...: http://forms.cbp.gov/pdf/CBP_Form_i760.pdf . Current Actions: CBP proposes to extend the expiration...

  7. 22 CFR 42.74 - Issuance of new or replacement visas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 42.74 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.74 Issuance of new or replacement visas. (a) New immigrant visa for a special immigrant under INA 101(a)(27)(A) and (B). (1) The consular...

  8. 22 CFR 42.73 - Procedure in issuing visas.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Procedure in issuing visas. 42.73 Section 42.73 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.73 Procedure in issuing visas. (a) Insertion of...

  9. 22 CFR 42.73 - Procedure in issuing visas.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Procedure in issuing visas. 42.73 Section 42.73 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.73 Procedure in issuing visas. (a) Insertion of...

  10. 22 CFR 42.73 - Procedure in issuing visas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Procedure in issuing visas. 42.73 Section 42.73 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.73 Procedure in issuing visas. (a) Insertion of...

  11. 22 CFR 42.73 - Procedure in issuing visas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Procedure in issuing visas. 42.73 Section 42.73 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.73 Procedure in issuing visas. (a) Insertion of...

  12. Novel combinations of vancomycin plus ceftaroline or oxacillin against methicillin-resistant vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous VISA.

    PubMed

    Werth, B J; Vidaillac, C; Murray, K P; Newton, K L; Sakoulas, G; Nonejuie, P; Pogliano, J; Rybak, M J

    2013-05-01

    We demonstrated a significant inverse correlation between vancomycin and beta-lactam susceptibilities in vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous VISA (hVISA) isolates. Using time-kill assays, vancomycin plus oxacillin or ceftaroline was synergistic against 3 of 5 VISA and 1 of 5 hVISA isolates or 5 of 5 VISA and 4 of 5 hVISA isolates, respectively. Beta-lactam exposure reduced overall vancomycin-Bodipy (dipyrromethene boron difluoride [4,4-difluoro-4-bora-3a,4a-diaza-s-indacene] fluorescent dye) binding but may have improved vancomycin-cell wall interactions to improve vancomycin activity. Further research is warranted to elucidate the mechanism behind vancomycin and beta-lactam synergy.

  13. Rapid Detection of Vancomycin-Intermediate Staphylococcus aureus by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry

    PubMed Central

    Mather, Cheryl A.; Werth, Brian J.; Sivagnanam, Shobini; SenGupta, Dhruba J.

    2016-01-01

    Vancomycin is the standard of care for the treatment of invasive methicillin-resistant Staphylococcus aureus (MRSA) infections. Infections with vancomycin-nonsusceptible MRSA, including vancomycin-intermediate S. aureus (VISA) and heterogeneous VISA (hVISA), are clinically challenging and are associated with poor patient outcomes. The identification of VISA in the clinical laboratory depends on standard susceptibility testing, which takes at least 24 h to complete after isolate subculture, whereas hVISA is not routinely detected in clinical labs. We therefore sought to determine whether VISA and hVISA can be differentiated from vancomycin-susceptible S. aureus (VSSA) using the spectra produced by matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS). Strains of MRSA were characterized for vancomycin susceptibility phenotype by broth microdilution and modified population analysis. We tested 21 VISA, 21 hVISA, and 38 VSSA isolates by MALDI-TOF MS. Susceptibility phenotypes were separated by using a support vector machine (SVM) machine learning algorithm. The resulting model was validated by leave-one-out cross validation. Models were developed and validated by using spectral profiles generated under various subculture conditions, as well as with and without hVISA strains. Using SVM, we correctly identified 100% of the VISA and 97% of the VSSA isolates with an overall classification accuracy of 98%. Addition of hVISA to the model resulted in 76% hVISA identification, 100% VISA identification, and 89% VSSA identification, for an overall classification accuracy of 89%. We conclude that VISA/hVISA and VSSA isolates are separable by MALDI-TOF MS with SVM analysis. PMID:26763961

  14. Rapid Detection of Vancomycin-Intermediate Staphylococcus aureus by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry.

    PubMed

    Mather, Cheryl A; Werth, Brian J; Sivagnanam, Shobini; SenGupta, Dhruba J; Butler-Wu, Susan M

    2016-04-01

    Vancomycin is the standard of care for the treatment of invasive methicillin-resistantStaphylococcus aureus(MRSA) infections. Infections with vancomycin-nonsusceptible MRSA, including vancomycin-intermediateS. aureus(VISA) and heterogeneous VISA (hVISA), are clinically challenging and are associated with poor patient outcomes. The identification of VISA in the clinical laboratory depends on standard susceptibility testing, which takes at least 24 h to complete after isolate subculture, whereas hVISA is not routinely detected in clinical labs. We therefore sought to determine whether VISA and hVISA can be differentiated from vancomycin-susceptibleS. aureus(VSSA) using the spectra produced by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). Strains of MRSA were characterized for vancomycin susceptibility phenotype by broth microdilution and modified population analysis. We tested 21 VISA, 21 hVISA, and 38 VSSA isolates by MALDI-TOF MS. Susceptibility phenotypes were separated by using a support vector machine (SVM) machine learning algorithm. The resulting model was validated by leave-one-out cross validation. Models were developed and validated by using spectral profiles generated under various subculture conditions, as well as with and without hVISA strains. Using SVM, we correctly identified 100% of the VISA and 97% of the VSSA isolates with an overall classification accuracy of 98%. Addition of hVISA to the model resulted in 76% hVISA identification, 100% VISA identification, and 89% VSSA identification, for an overall classification accuracy of 89%. We conclude that VISA/hVISA and VSSA isolates are separable by MALDI-TOF MS with SVM analysis. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  15. Visa refusal following compulsory hospital admission under the Mental Health Act 1983 (England and Wales): fact or fiction?

    PubMed

    Ashmore, R

    2015-08-01

    Historically, compulsory hospital admission led to discrimination for service users. For example, until recently detention under the Mental Health Act 1983 (England and Wales) would disqualify a person from being a Member of Parliament. There is a belief among mental health professionals that compulsory hospital admission will result in service users being refused a tourist visa. However, there is a paucity of literature on this topic, particularly from an international perspective. Based on the information reviewed in this study, there is no evidence to support this belief. Of 262 travel destinations, 96 (36.6%) require British citizens to obtain a tourist visa. Six (2.3%) destinations require applicants to declare a mental health condition in order to obtain a tourist visa. None of these destinations ask applicants to declare a history of compulsory hospital admission. However, the possibility exists that anyone declaring a mental health problem may be asked to provide further information about their condition before a visa is granted. Mental health nurses require education to ensure that their knowledge of mental health legislation is up to date. This education should include information on the potential consequences of compulsory hospital admission for the service user's social life following discharge. Service users and their families should be provided with written information on the potential social impact of detention along with a list of organizations that can provide advice on specific issues. This study sought to establish whether a history of compulsory hospital admission prevented a person from obtaining a tourist visa. A visa application form and/or other relevant information were obtained for 262 travel destinations visited by British citizens. Ninety-six (36.6%) destinations require British citizens to obtain a tourist visa. All visas are issued subject to travellers meeting a number of conditions, for example being in possession of travel insurance. Six (2.3%) destinations (Australia, China, Guam, Puerto Rico, Russia and the USA) ask applicants to declare a mental health condition. None of these destinations require applicants to disclose whether they have been admitted to hospital, either informal or under a section of the Mental Health Act 1983. However, the possibility exists that anyone declaring a mental health problem may be asked to provide further information about their condition before a visa is granted. Mental health professionals need to acquire accurate knowledge of the potential consequences of compulsory hospital admission. This will enable them to support service users more effectively. Similarly, service users need to be aware of the implications of detention for their social life following discharge from hospital. Further research is required in this area, particularly from an international perspective. © 2015 John Wiley & Sons Ltd.

  16. Prevalence of Slow-Growth Vancomycin Nonsusceptibility in Methicillin-Resistant Staphylococcus aureus

    PubMed Central

    Azechi, Takuya; Miyazaki, Motoyasu; Takata, Tohru; Sekine, Miwa; Matsui, Hidehito; Hanaki, Hideaki; Yahara, Koji; Sasano, Hiroshi; Asakura, Kota; Takaku, Tomoiku; Ochiai, Tomonori; Komatsu, Norio; Chambers, Henry F.

    2017-01-01

    ABSTRACT We previously reported a novel phenotype of vancomycin-intermediate Staphylococcus aureus (VISA), i.e., “slow VISA,” whose colonies appear only after 72 h of incubation. Slow-VISA strains can be difficult to detect because prolonged incubation is required and the phenotype is unstable. To develop a method for detection of slow-VISA isolates, we studied 23 slow-VISA isolates derived from the heterogeneous VISA (hVISA) clinical strain Mu3. We identified single nucleotide polymorphisms (SNPs) in genes involved in various pathways which have been implicated in the stringent response, such as purine/pyrimidine synthesis, cell metabolism, and cell wall peptidoglycan synthesis. We found that mupirocin, which also induces the stringent response, caused stable expression of vancomycin resistance. On the basis of these results, we developed a method for detection of slow-VISA strains by use of 0.032 μg/ml mupirocin (Yuki Katayama, 7 March 2017, patent application PCT/JP2017/008975). Using this method, we detected 53 (15.6%) slow-VISA isolates among clinical methicillin-resistant S. aureus (MRSA) isolates. In contrast, the VISA phenotype was detected in fewer than 1% of isolates. Deep-sequencing analysis showed that slow-VISA clones are present in small numbers among hVISA isolates and proliferate in the presence of vancomycin. This slow-VISA subpopulation may account in part for the recurrence and persistence of MRSA infection. PMID:28827421

  17. Regulations of 28 April 1989 on the issuance of visas.

    PubMed

    1989-01-01

    These Venezuelan Regulations set forth the rules on the issuance of tourist visas, temporary visas, temporary business visas, temporary student visas, temporary labor visas, and transit visas. In order to obtain a tourist visa a person must have a passport and in certain cases be able to prove that he or she has sufficient financial resources to cover the costs of staying in Venezuela. In order to obtain a temporary visa a person must have a passport, an officially certified police record, proof of civil status, and proof of a satisfactory medical examination. In order to obtain a temporary business visa a person must have a passport, documents proving his or her business objectives, and, when applicable, documents showing that he or she owns a business. In order to obtain a temporary student visa a person must have a passport, proof of sufficient economic resources, proof of a satisfactory medical examination, and documents attesting admittance to an educational program; he or she must also state that he will not engage in paid activities. In order to obtain a temporary labor visa a person must have documents proving employment, a document from the business or person employing him or her stating that it will cover the costs of the person's residence and departure, proof of satisfactory medical examination, and an officially certified police record; in addition, the employer must ask the authorities for permission to hire him or her. In order to obtain a transit visa a person must have a passport, confirmed passage to a 3rd country, and transportation documents. This visa is valid for 72 hours; all other visas are valid for 1 year.

  18. 75 FR 76997 - Agency Information Collection Activities: Arrival and Departure Record (Forms I-94 and I-94W) and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-10

    ... Activities: Arrival and Departure Record (Forms I-94 and I-94W) and Electronic System for Travel... I-94W (Nonimmigrant Visa Waiver Arrival/Departure), and the Electronic System for Travel... points: [[Page 76998

  19. Screening for tuberculosis in migrants and visitors from high incidence settings: present and future perspectives.

    PubMed

    Dobler, Claudia C; Fox, Greg J; Douglas, Paul; Viney, Kerri A; Ahmad Khan, Faiz; Temesgen, Zelalem; Marais, Ben J

    2018-05-24

    In most settings with a low incidence of tuberculosis (TB), foreign-born people make up the majority of TB cases, but the distribution of the TB risk among different migrant populations is often poorly quantified. In addition, screening practices for TB disease and latent TB infection vary widely. Addressing the risk of TB in international migrants is an essential component of TB prevention and care efforts in low incidence countries, and strategies to systematically screen for, diagnose, treat and prevent TB among this group contribute to national and global TB elimination goals.This review provides an overview and critical assessment of TB screening practices that are focused on migrants and visitors from high to low TB incidence countries, including pre-migration screening and post-migration follow-up of those deemed to be at an increased risk of developing TB. We focus mainly on migrants who enter the destination country via application for a long-stay visa, as well as asylum seekers and refugees, but briefly consider issues related to short-term visitors and those with long duration multiple-entry visas. Issues related to the screening of children and screening for latent TB infection are also explored. Copyright ©ERS 2018.

  20. Contribution of Selected Gene Mutations to Resistance in Clinical Isolates of Vancomycin-Intermediate Staphylococcus aureus

    PubMed Central

    Hafer, Cory; Lin, Ying; Kornblum, John; Lowy, Franklin D.

    2012-01-01

    Infections with vancomycin-intermediate Staphylococcus aureus (VISA) have been associated with vancomycin treatment failures and poor clinical outcomes. Routine identification of clinical isolates with increased vancomycin MICs remains challenging, and no molecular marker exists to aid in diagnosis of VISA strains. We tested vancomycin susceptibilities by using microscan, Etest, and population analyses in a collection of putative VISA, methicillin-resistant S. aureus, and methicillin-sensitive S. aureus (VSSA) infectious isolates from community- or hospital-associated S. aureus infections (n = 77) and identified 22 VISA and 9 heterogeneous VISA (hVISA) isolates. Sequencing of VISA candidate loci vraS, vraR, yvqF, graR, graS, walR, walK, and rpoB revealed a high diversity of nonsynonymous single-nucleotide polymorphisms (SNPs). For vraS, vraR, yvqF, walK, and rpoB, SNPs were more frequently present in VISA and hVISA than in VSSA isolates, whereas mutations in graR, graS, and walR were exclusively detected in VISA isolates. For each of the individual loci, SNPs were only detected in about half of the VISA isolates. All but one VISA isolate had at least one SNP in any of the genes sequenced, and isolates with an MIC of 6 or 8 μg/ml harbored at least 2 SNPs. Overall, increasing vancomycin MICs were paralleled by a higher proportion of isolates with SNPs. Depending on the clonal background, SNPs appeared to preferentially accumulate in vraS and vraR for sequence type 8 (ST8) and in walK and walR for ST5 isolates. Taken together, by comparing VISA, hVISA, and VSSA controls, we observed preferential clustering of SNPs in VISA candidate genes, with an unexpectedly high diversity across these loci. Our results support a polygenetic etiology of VISA. PMID:22948864

  1. 75 FR 39323 - Amendment to the Biometric Visa Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... DEPARTMENT OF STATE [Public Notice: 7047] Amendment to the Biometric Visa Program AGENCY: Department of State. ACTION: Notice of Amendment to the Biometric Visa Program. This public notice announces an amendment to the Biometric Visa Program. Section 303 of the Enhanced Border Security and Visa...

  2. 22 CFR 42.51 - Department control of numerical limitations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ....51 Section 42.51 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER... shall limit the number of immigrant visas that may be issued and the number of adjustments of status... Department shall allocate immigrant visa numbers for use in connection with the issuance of immigrant visas...

  3. 22 CFR 42.82 - Revocation of visas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Revocation of visas. 42.82 Section 42.82 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusal, Revocation, and Termination of Registration § 42.82 Revocation of visas...

  4. 22 CFR 42.82 - Revocation of visas.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Revocation of visas. 42.82 Section 42.82 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusal, Revocation, and Termination of Registration § 42.82 Revocation of visas...

  5. 22 CFR 42.82 - Revocation of visas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Revocation of visas. 42.82 Section 42.82 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusal, Revocation, and Termination of Registration § 42.82 Revocation of visas...

  6. 22 CFR 41.122 - Revocation of visas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Revocation of visas. 41.122 Section 41.122 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusals and Revocations § 41.122 Revocation of visas. (a) Grounds for...

  7. 22 CFR 42.51 - Department control of numerical limitations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ....51 Section 42.51 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER... shall limit the number of immigrant visas that may be issued and the number of adjustments of status... Department shall allocate immigrant visa numbers for use in connection with the issuance of immigrant visas...

  8. 22 CFR 41.122 - Revocation of visas.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Revocation of visas. 41.122 Section 41.122 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusals and Revocations § 41.122 Revocation of visas. (a) Grounds for...

  9. 22 CFR 41.122 - Revocation of visas.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Revocation of visas. 41.122 Section 41.122 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusals and Revocations § 41.122 Revocation of visas. (a) Grounds for...

  10. 22 CFR 42.82 - Revocation of visas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Revocation of visas. 42.82 Section 42.82 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusal, Revocation, and Termination of Registration § 42.82 Revocation of visas...

  11. 22 CFR 41.121 - Refusal of individual visas.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Refusal of individual visas. 41.121 Section 41.121 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusals and Revocations § 41.121 Refusal of individual visas. (a...

  12. 22 CFR 41.121 - Refusal of individual visas.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Refusal of individual visas. 41.121 Section 41.121 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusals and Revocations § 41.121 Refusal of individual visas. (a...

  13. 22 CFR 41.122 - Revocation of visas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Revocation of visas. 41.122 Section 41.122 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusals and Revocations § 41.122 Revocation of visas. (a) Grounds for...

  14. 22 CFR 42.51 - Department control of numerical limitations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ....51 Section 42.51 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER... shall limit the number of immigrant visas that may be issued and the number of adjustments of status... Department shall allocate immigrant visa numbers for use in connection with the issuance of immigrant visas...

  15. 22 CFR 41.122 - Revocation of visas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Revocation of visas. 41.122 Section 41.122 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusals and Revocations § 41.122 Revocation of visas. (a) Grounds for...

  16. 22 CFR 41.121 - Refusal of individual visas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Refusal of individual visas. 41.121 Section 41.121 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusals and Revocations § 41.121 Refusal of individual visas. (a...

  17. 22 CFR 42.82 - Revocation of visas.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Revocation of visas. 42.82 Section 42.82 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusal, Revocation, and Termination of Registration § 42.82 Revocation of visas...

  18. 22 CFR 41.121 - Refusal of individual visas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Refusal of individual visas. 41.121 Section 41.121 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusals and Revocations § 41.121 Refusal of individual visas. (a...

  19. 22 CFR 41.121 - Refusal of individual visas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Refusal of individual visas. 41.121 Section 41.121 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Refusals and Revocations § 41.121 Refusal of individual visas. (a...

  20. Combination of cephalosporins with vancomycin or teicoplanin enhances antibacterial effect of glycopeptides against heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) and VISA.

    PubMed

    Lai, Chih-Cheng; Chen, Chi-Chung; Chuang, Yin-Ching; Tang, Hung-Jen

    2017-01-31

    Eight heterogeneous vancomycin-intermediate S. aureus (h-VISA) and seven VISA clinical isolates confirmed by the population analysis profile/area under the curve ratio (PAP/AUC) were collected. We further performed the PAP/AUC, time-killing methods and MIC tests using vancomycin/teicoplanin alone or combination with susceptible breakpoint concentrations of cefazolin, cefmetazole, cefotaxime, and cefepime for these isolates. The PAP/AUC MIC curve shifted left after addition of cephalosporins with vancomycin or teicoplanin for both h-VISA and VISA isolates. With the combination of different cephalosporins with vancomycin or teicoplanin, the AUC/Mu3 AUC ratio decreased to <0.9 for the standard Mu3 isolate which are compatible with the definition of vancomycin susceptible S. aureus. These decreases ranged between 1.81-2.02 and 2.37-2.85-fold for h-VISA treated with cephalosporins and vancomycin or teicoplanin, and 2.05-4.59, and 2.93-4,89-fold for VISA treated with cephalosporins with vancomycin or teicoplanin. As measured by time-killing assays, the combinations of different cephalosporins with vancomycin concentrations at 1/2 and 1/4 MIC, exhibited a bactericidal and bacteriostatic effect in VISA. The mean fold of MIC decline for vancomycin base combinations ranged from 1.81-3.83 and 2.71-9.33 for h-VISA and VISA, respectively. Overall, this study demonstrated the enhanced antibacterial activity of vancomycin/teicoplanin after adding cephalosporins against clinical h-VISA/VISA isolates.

  1. A mutation of RNA polymerase β' subunit (RpoC) converts heterogeneously vancomycin-intermediate Staphylococcus aureus (hVISA) into "slow VISA".

    PubMed

    Matsuo, Miki; Hishinuma, Tomomi; Katayama, Yuki; Hiramatsu, Keiichi

    2015-07-01

    Various mutations in the rpoB gene, which encodes the RNA polymerase β subunit, are associated with increased vancomycin (VAN) resistance in vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneously VISA (hVISA) strains. We reported that rpoB mutations are also linked to the expression of the recently found "slow VISA" (sVISA) phenotype (M. Saito, Y. Katayama, T. Hishinuma, A. Iwamoto, Y. Aiba, K Kuwahara-Arai, L. Cui, M. Matsuo, N. Aritaka, and K. Hiramatsu, Antimicrob Agents Chemother 58:5024-5035, 2014, http://dx.doi.org/10.1128/AAC.02470-13). Because RpoC and RpoB are components of RNA polymerase, we examined the effect of the rpoC(P440L) mutation on the expression of the sVISA phenotype in the Mu3fdh2*V6-5 strain (V6-5), which was derived from a previously reported hVISA strain with the VISA phenotype. V6-5 had an extremely prolonged doubling time (DT) (72 min) and high vancomycin MIC (16 mg/liter). However, the phenotype of V6-5 was unstable, and the strain frequently reverted to hVISA with concomitant loss of low growth rate, cell wall thickness, and reduced autolysis. Whole-genome sequencing of phenotypic revertant strain V6-5-L1 and comparison with V6-5 revealed a second mutation, F562L, in rpoC. Introduction of the wild-type (WT) rpoC gene using a multicopy plasmid resolved the sVISA phenotype of V6-5, indicating that the rpoC(P440L) mutant expressed the sVISA phenotype in hVISA. To investigate the mechanisms of resistance in the sVISA strain, we independently isolated an additional 10 revertants to hVISA and VISA. In subsequent whole-genome analysis, we identified compensatory mutations in the genes of three distinct functional categories: the rpoC gene itself as regulatory mutations, peptidoglycan biosynthesis genes, and relQ, which is involved in the stringent response. It appears that the rpoC(P440L) mutation causes the sVISA phenotype by augmenting cell wall peptidoglycan synthesis and through the control of the stringent response. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  2. 22 CFR 42.52 - Post records of visa applications.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Post records of visa applications. 42.52 Section 42.52 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Numerical Controls and Priority Dates § 42.52 Post records of visa...

  3. 22 CFR 42.52 - Post records of visa applications.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Post records of visa applications. 42.52 Section 42.52 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Numerical Controls and Priority Dates § 42.52 Post records of visa...

  4. 22 CFR 42.52 - Post records of visa applications.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Post records of visa applications. 42.52 Section 42.52 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Numerical Controls and Priority Dates § 42.52 Post records of visa...

  5. 22 CFR 41.11 - Entitlement to nonimmigrant status.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Section 41.11 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... visa, other than an alien applying for a visa under INA 101(a)(15) (H)(i) or (L), shall be presumed to... the applicant to establish entitlement for nonimmigrant status and the type of nonimmigrant visa for...

  6. 22 CFR 41.11 - Entitlement to nonimmigrant status.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Section 41.11 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... visa, other than an alien applying for a visa under INA 101(a)(15) (H)(i) or (L), shall be presumed to... the applicant to establish entitlement for nonimmigrant status and the type of nonimmigrant visa for...

  7. 22 CFR 41.11 - Entitlement to nonimmigrant status.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 41.11 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... visa, other than an alien applying for a visa under INA 101(a)(15) (H)(i) or (L), shall be presumed to... the applicant to establish entitlement for nonimmigrant status and the type of nonimmigrant visa for...

  8. 22 CFR 41.59 - Professionals under the North American Free Trade Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Trade Agreement. 41.59 Section 41.59 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.59...) Visa validity. The period of validity of a visa issued pursuant to paragraph (a) of this section may...

  9. 22 CFR 41.11 - Entitlement to nonimmigrant status.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Section 41.11 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... visa, other than an alien applying for a visa under INA 101(a)(15) (H)(i) or (L), shall be presumed to... the applicant to establish entitlement for nonimmigrant status and the type of nonimmigrant visa for...

  10. 22 CFR 42.52 - Post records of visa applications.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Post records of visa applications. 42.52 Section 42.52 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Numerical Controls and Priority Dates § 42.52 Post records of visa...

  11. 22 CFR 42.74 - Issuance of new or replacement visas.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Issuance of new or replacement visas. 42.74 Section 42.74 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.74 Issuance of new or replacement...

  12. 22 CFR 42.52 - Post records of visa applications.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Post records of visa applications. 42.52 Section 42.52 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Numerical Controls and Priority Dates § 42.52 Post records of visa...

  13. 22 CFR 42.74 - Issuance of new or replacement visas.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Issuance of new or replacement visas. 42.74 Section 42.74 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.74 Issuance of new or replacement...

  14. 22 CFR 42.74 - Issuance of new or replacement visas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Issuance of new or replacement visas. 42.74 Section 42.74 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.74 Issuance of new or replacement...

  15. 22 CFR 42.74 - Issuance of new or replacement visas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Issuance of new or replacement visas. 42.74 Section 42.74 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Issuance of Immigrant Visas § 42.74 Issuance of new or replacement...

  16. 22 CFR 41.11 - Entitlement to nonimmigrant status.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 41.11 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... visa, other than an alien applying for a visa under INA 101(a)(15) (H)(i) or (L), shall be presumed to... the applicant to establish entitlement for nonimmigrant status and the type of nonimmigrant visa for...

  17. 78 FR 18457 - Definition of Form I-94 To Include Electronic Format

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-27

    ... parole stamp in a foreign passport to the list of documents designated as evidence of alien registration... will create a Form I-94 in an electronic format based on passenger, passport and visa information DHS... inspection. The officer stamps the Form I-94 and the alien's passport, detaches the bottom portion of the...

  18. 76 FR 27373 - 30-Day Notice of Proposed Information Collection: Medical Examination Forms for Immigrant or...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ...: Medical Examination Forms for Immigrant or Refugee Applicants ACTION: Notice of request for public comment... Examination for Immigrant or Refugee Applicant. OMB Control Number: 1405-0113. Type of Request: Revision of a.../VO). Form Number: DS-2053, DS-2054, DS-3030, DS-3024, DS-3025, DS-3026. Respondents: Immigrant visa...

  19. 8 CFR 204.313 - Filing and adjudication of a Form I-800.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204.313 Filing and adjudication of a... I-800 either that: (i) The child will seek an immigrant visa, if the Form I-800 is approved, because... completed waiver application for each such ground; and (6) Either a Form I-864W, Intending Immigrant's I-864...

  20. The Prevalence of Vancomycin-Intermediate Staphylococcus aureus and Heterogeneous VISA Among Methicillin-Resistant Strains Isolated from Pediatric Population in a Turkish University Hospital.

    PubMed

    Mirza, Hasan Cenk; Sancak, Banu; Gür, Deniz

    2015-10-01

    There are limited data regarding the prevalence of vancomycin-intermediate Staphylococcus aureus (VISA)/heterogeneous VISA (hVISA) among pediatric population. Our objective was to determine the distribution of vancomycin and daptomycin minimum inhibitory concentrations (MICs) and explore the phenomenon of vancomycin MIC creep and the VISA/hVISA prevalence among the methicillin-resistant Staphylococcus aureus (MRSA) strains belonging to pediatric population by population analysis profile-area under the curve (PAP-AUC) and Etest macromethod. Vancomycin and daptomycin susceptibilities of 94 pediatric isolates of MRSA were tested by broth microdilution (BMD) and Etest methods. To determine the prevalence of VISA/hVISA, Etest macromethod and PAP-AUC was performed on all isolates. All isolates were susceptible to vancomycin and daptomycin by both BMD and Etest methods. Twenty-eight (29.8%) isolates had vancomycin MICs of 2 μg/ml by BMD. No increase in vancomycin MICs was observed over time. There were no VISA among 94 MRSA tested but 20 (21.3%) hVISA isolates were identified by PAP-AUC. Results of Etest macromethod were compared to PAP-AUC. Etest macromethod was 60.0% sensitive and 90.5% specific. The hVISA isolates represented 53.6% of isolates with vancomycin MICs of 2 μg/ml. Also, 75% of hVISA isolates had vancomycin MICs of 2 μg/ml. To our knowledge, this is the first study investigating the prevalence of VISA/hVISA among MRSA isolated from pediatric patients by PAP-AUC method. Based on our findings, MRSA isolates, which have vancomycin MIC of 2 μg/ml can be investigated for the presence of hVISA. In this study, daptomycin showed potent activity against all isolates and may represent a therapeutic option for MRSA infections.

  1. The evolution of vancomycin intermediate Staphylococcus aureus (VISA) and heterogenous-VISA.

    PubMed

    Howden, Benjamin P; Peleg, Anton Y; Stinear, Timothy P

    2014-01-01

    Resistance to new antimicrobials is generally recognized in Staphylococcus aureus soon after they are released for clinical use. In the case of vancomycin, which was first released in the 1950s, resistance was not reported until the mid 1990s, with the description of vancomycin-intermediate S. aureus (VISA), and heterogenous-VISA (hVISA). Unraveling the complex genetic and cell wall structural changes conferring low-level vancomycin resistance in S. aureus has proved challenging. However the recent advances in high throughput whole-genome sequencing has played a key role in determining the breadth of bacterial chromosomal changes linked with resistance. Diverse mutations in a small number of staphylococcal regulatory genes, in particular walKR, graRS, vraSR and rpoB, have been associated with hVISA and VISA. Only a small number of these mutations have been experimentally proven to confer the resistance phenotype and some of these only partially contribute to resistance. It also appears that the evolution of VISA from VSSA is a step-wise process. Transcriptomics studies, and analysis of host pathogen interactions, indicate that the evolution of vancomycin-susceptible S. aureus to VISA is associated not only with antibiotic resistance, but with other changes likely to promote persistent infection. These include predicted alterations in central metabolism, altered expression of virulence associated factors, attenuated virulence in vivo, and alterations in susceptibility to host innate immune responses, together with reduced susceptibility to other antibiotics. In fact, current data suggests that hVISA and VISA represent a bacterial evolutionary state favoring persistence in the face of not only antibiotics, but also the host environment. The additional knowledge of staphylococcal biology that has been uncovered during the study of hVISA and VISA is significant. The present review will detail the current understanding of the evolutionary process in the generation of hVISA and VISA, and explore the diverse additional changes that occur in these strains. Copyright © 2013 Elsevier B.V. All rights reserved.

  2. Novel function of Trim44 promotes an antiviral response by stabilizing VISA.

    PubMed

    Yang, Bo; Wang, Jie; Wang, Yanming; Zhou, Haiyan; Wu, Xiaodong; Tian, Zhigang; Sun, Bing

    2013-04-01

    Virus-induced signaling adaptor (VISA) functions as a critical adaptor in the regulation of both the production of type I IFNs and the subsequent control of the innate antiviral response. In this study, we demonstrate that tripartite motif (Trim)44 interacts with VISA and promotes VISA-mediated antiviral responses. The overexpression of Trim44 enhances the cellular response to viral infection, whereas Trim44 knockdown yields the opposite effect. Trim44 stabilizes VISA by preventing VISA ubiquitination and degradation. These findings suggest that Trim44 functions as a positive regulator of the virus-triggered immune response by enhancing the stability of VISA.

  3. Successful infection control for a vancomycin-intermediate Staphylococcus aureus outbreak in an advanced emergency medical service centre.

    PubMed

    Sakai, Y; Qin, L; Miura, M; Masunaga, K; Tanamachi, C; Iwahashi, J; Kida, Y; Takasu, O; Sakamoto, T; Watanabe, H

    2016-04-01

    A vancomycin-intermediate Staphylococcus aureus (VISA) (vancomycin minimum inhibitory concentration: 4mg/L) outbreak occurred in an advanced emergency medical service centre [hereafter referred to as the intensive care unit (ICU)] between 2013 and 2014. Our objective was to evaluate the infection control measures that were successful. Seventeen VISA strains were isolated from the sputum of 15 inpatients and the skin of two inpatients. Fourteen VISA strains were recognized as colonization. However, three VISA strains were isolated from the sputum of three inpatients with pneumonia. Environmental cultures were performed and VISA strains were detected in five of 65 sites. Pulsed-field gel electrophoresis (PFGE) and multi-locus sequence typing (MLST) was performed on 21 VISA strains. Molecular typing including PFGE and MLST showed that the patterns of 19 VISA strains were identical and those of the other two VISA strains were possibly related. This meant that a horizontal transmission of VISA strains had occurred in the ICU. In August 2013, the infection control team began interventions. However, new inpatients with VISA strains continued to appear. Therefore, in October 2013, the ICU was partially closed in order to try to prevent further horizontal transmission, and existing inpatients with the VISA strain were isolated. Although new cases quickly dissipated after the partial closure, it took approximately five months to eradicate the VISA outbreak. Our data suggest that despite the employment of various other infection control measures, partial closure of the ICU was essential in terminating this VISA outbreak. Copyright © 2016 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  4. Combination of cephalosporins with vancomycin or teicoplanin enhances antibacterial effect of glycopeptides against heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) and VISA

    PubMed Central

    Lai, Chih-Cheng; Chen, Chi-Chung; Chuang, Yin-Ching; Tang, Hung-Jen

    2017-01-01

    Eight heterogeneous vancomycin-intermediate S. aureus (h-VISA) and seven VISA clinical isolates confirmed by the population analysis profile/area under the curve ratio (PAP/AUC) were collected. We further performed the PAP/AUC, time-killing methods and MIC tests using vancomycin/teicoplanin alone or combination with susceptible breakpoint concentrations of cefazolin, cefmetazole, cefotaxime, and cefepime for these isolates. The PAP/AUC MIC curve shifted left after addition of cephalosporins with vancomycin or teicoplanin for both h-VISA and VISA isolates. With the combination of different cephalosporins with vancomycin or teicoplanin, the AUC/Mu3 AUC ratio decreased to <0.9 for the standard Mu3 isolate which are compatible with the definition of vancomycin susceptible S. aureus. These decreases ranged between 1.81–2.02 and 2.37–2.85-fold for h-VISA treated with cephalosporins and vancomycin or teicoplanin, and 2.05–4.59, and 2.93–4,89-fold for VISA treated with cephalosporins with vancomycin or teicoplanin. As measured by time-killing assays, the combinations of different cephalosporins with vancomycin concentrations at 1/2 and 1/4 MIC, exhibited a bactericidal and bacteriostatic effect in VISA. The mean fold of MIC decline for vancomycin base combinations ranged from 1.81–3.83 and 2.71–9.33 for h-VISA and VISA, respectively. Overall, this study demonstrated the enhanced antibacterial activity of vancomycin/teicoplanin after adding cephalosporins against clinical h-VISA/VISA isolates. PMID:28139739

  5. 22 CFR 40.205 - Applicant for immigrant visa under INA 203(c).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Applicant for immigrant visa under INA 203(c). 40.205 Section 40.205 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH... § 40.205 Applicant for immigrant visa under INA 203(c). An alien shall be ineligible to receive a visa...

  6. 22 CFR 40.205 - Applicant for immigrant visa under INA 203(c).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Applicant for immigrant visa under INA 203(c). 40.205 Section 40.205 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH... § 40.205 Applicant for immigrant visa under INA 203(c). An alien shall be ineligible to receive a visa...

  7. 22 CFR 40.205 - Applicant for immigrant visa under INA 203(c).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Applicant for immigrant visa under INA 203(c). 40.205 Section 40.205 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH... § 40.205 Applicant for immigrant visa under INA 203(c). An alien shall be ineligible to receive a visa...

  8. 22 CFR 40.205 - Applicant for immigrant visa under INA 203(c).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Applicant for immigrant visa under INA 203(c). 40.205 Section 40.205 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH... § 40.205 Applicant for immigrant visa under INA 203(c). An alien shall be ineligible to receive a visa...

  9. Heterogeneous Vancomycin-Intermediate Susceptibility Phenotype in Bloodstream Methicillin-Resistant Staphylococcus aureus Isolates from an International Cohort of Patients with Infective Endocarditis: Prevalence, Genotype, and Clinical Significance

    PubMed Central

    Bae, In-Gyu; Federspiel, Jerome J.; Miro, Jose M.; Woods, Christopher W.; Park, Lawrence; Rybak, Michael J.; Rude, Thomas H.; Bradley, Suzanne; Bukovski, Suzana; de la Maria, Cristina Garcia; Kanj, Souha S.; Korman, Tony; Marco, Francesc; Murdoch, David R.; Plesiat, Patrick; Rodriguez-Creixems, Marta; Ryan, Suzanne; Steed, Lisa; Tattevin, Pierre; Tripodi, Marie-Françoise; Newton, Karly L.; Corey, G. Ralph; Fowler, Vance G.

    2013-01-01

    Background The significance of heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) is unknown. Using a multinational collection of isolates from methicillin-resistant S. aureus (MRSA) infective endocarditis (IE), we characterized IE patients with and without hVISA, and genotyped the infecting strains. Methods MRSA bloodstream isolates from 65 patients with definite IE from 8 countries underwent PCR for 31 virulence genes, pulsed-field gel electrophoresis, and multilocus sequence typing. hVISA was defined using population analysis profiling (PAP). Results Nineteen (29.2%) of 65 MRSA IE isolates exhibited hVISA by PAP. Isolates from Oceania and Europe were more likely to exhibit hVISA than isolates from the United States (77.8% vs. 35.0% vs. 13.9%; P < .001). The prevalence of hVISA was higher among isolates with a vancomycin minimum inhibitory concentration of 2 mg/L (P = .026). hVISA-infected patients were more likely to have persistent bacteremia (68.4% vs. 37.0%; P = .029) and heart failure (47.4% vs. 19.6%; P = .033). Mortality of hVISA- and non-hVISA-infected patients did not differ (42.1% vs. 34.8%, P = .586). hVISA and non-hVISA isolates were genotypically similar. Conclusions In these analyses, hVISA occurred in over one-quarter of MRSA IE isolates, was associated with certain IE complications, and varied in frequency by geographic region. PMID:19811099

  10. Heterogeneous vancomycin-intermediate susceptibility phenotype in bloodstream methicillin-resistant Staphylococcus aureus isolates from an international cohort of patients with infective endocarditis: prevalence, genotype, and clinical significance.

    PubMed

    Bae, In-Gyu; Federspiel, Jerome J; Miró, José M; Woods, Christopher W; Park, Lawrence; Rybak, Michael J; Rude, Thomas H; Bradley, Suzanne; Bukovski, Suzana; de la Maria, Cristina Garcia; Kanj, Souha S; Korman, Tony M; Marco, Francesc; Murdoch, David R; Plesiat, Patrick; Rodriguez-Creixems, Marta; Reinbott, Porl; Steed, Lisa; Tattevin, Pierre; Tripodi, Marie-Françoise; Newton, Karly L; Corey, G Ralph; Fowler, Vance G

    2009-11-01

    The significance of heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) is unknown. Using a multinational collection of isolates from methicillin-resistant S. aureus (MRSA) infective endocarditis (IE), we characterized patients with IE with and without hVISA, and we genotyped the infecting strains. MRSA bloodstream isolates from 65 patients with definite IE from 8 countries underwent polymerase chain reaction (PCR) for 31 virulence genes, pulsed-field gel electrophoresis, and multilocus sequence typing. hVISA was defined using population analysis profiling. Nineteen (29.2%) of 65 MRSA IE isolates exhibited the hVISA phenotype by population analysis profiling. Isolates from Oceania and Europe were more likely to exhibit the hVISA phenotype than isolates from the United States (77.8% and 35.0% vs 13.9%; P < .001). The prevalence of hVISA was higher among isolates with a vancomycin minimum inhibitory concentration of 2 mg/L (P = .026). hVISA-infected patients were more likely to have persistent bacteremia (68.4% vs 37.0%; P = .029) and heart failure (47.4% vs 19.6%; P = .033). Mortality did not differ between hVISA- and non-hVISA-infected patients (42.1% vs 34.8%, P = .586). hVISA and non-hVISA isolates were genotypically similar. In these analyses, the hVISA phenotype occurred in more than one-quarter of MRSA IE isolates, was associated with certain IE complications, and varied in frequency by geographic region.

  11. Clinical features and treatment outcomes of vancomycin-intermediate Staphylococcus aureus (VISA) and heteroresistant vancomycin-intermediate Staphylococcus aureus (hVISA) in a tertiary care institution in Singapore.

    PubMed

    Fong, R K C; Low, J; Koh, T H; Kurup, A

    2009-08-01

    This retrospective case-control study was undertaken to review the clinical features associated with heteroresistant vancomycin-intermediate Staphylococcus aureus (hVISA) and vancomycin-intermediate S. aureus (VISA) infections and the local impact they have on clinical outcome. Compared with vancomycin-susceptible S. aureus (n = 30), hVISA and VISA infections (n = 10) are found to be associated with a longer period of prior glycopeptide use (P = 0.01), bone/joint (P < 0.01) and prosthetic infections (P = 0.04), as well as treatment failure, as evidenced by longer bacteremic (P < 0.01) and culture positivity (P < 0.01) periods. This was observed to have resulted in longer hospital length of stay (P < 0.01) and total antibiotic therapy duration (P = 0.01). There was, however, no significant difference in the overall patient mortality or the hospitalization cost (P = 0.12) in both groups. Clinicians should be cognizant of the association between hVISA/VISA with high bacterial load deep-seated infections. We recommend targeted and even universal screening for hVISA/VISA in methicillin-resistant S. aureus (MRSA) infections.

  12. [Validation of the VISA-A-G questionnaire for German-speaking patients suffering from Haglund's disease].

    PubMed

    Lohrer, H; Nauck, T

    2010-06-01

    The VISA-A questionnaire is currently the only valid, reliable, and disease specific patient administered questionnaire for research in Achilles tendinopathy. To perform multinational and multilingual investigations this instrument was already adapted to several languages. According to the "guidelines for the process of cross-cultural adaptation of self-report measures" we already translated and validated the VISA-A questionnaire for patients with Achilles tendinopathy. To cross-culturally adapt and validate the VISA-A Questionnaire for German-speaking patients suffering from Haglund's disease. The VISA-A-G questionnaire was tested for reliability, validity, and internal consistency in 39 Haglund's disease patients and 79 asymptomatic persons. For concurrent validity the VISA-A-G was compared with the Curwin and Stanish tendon grading system and with the Percy and Conochie classification system for the effect of pain on athletic performance. VISA-A-G results in Haglund's disease were additionally compared with VISA-A-G results obtained from Achilles tendinopathy patients and with VISA-A results presented in the international literature. ICC for the VISA-A-G questionnaire in conservatively treated Haglund's disease patients was 0.96. In asymptomatic students and joggers ICC was 0.97 and 0.60. When correlated with the grading system of Curwin and Stanish and with the Percy and Conochie classification rho was -0.95 and 0.94, respectively. Internal consistency (Cronbach's alpha) for the total VISA-A-G scores of the patients was calculated to be 0.87. Compared with VISA-A-G results obtained from Achilles tendinopathy patients there was no relevant difference discernible. Compared with VISA-A results presented in the original publication no difference was found statistically for students, healthy people, conservative, and preoperative patients, respectively. This study confirms that the VISA-A-G is a valid and reliable measure for German-speaking patients suffering from Haglund's disease. Georg Thieme Verlag KG Stuttgart, New York.

  13. Validity and reliability of the French translation of the VISA-A questionnaire for Achilles tendinopathy.

    PubMed

    Kaux, Jean-François; Delvaux, François; Oppong-Kyei, Julian; Dardenne, Nadia; Beaudart, Charlotte; Buckinx, Fanny; Croisier, Jean-Louis; Forthomme, Bénédicte; Crielaard, Jean-Michel; Bruyère, Oliver

    2016-12-01

    The Victorian Institute of Sport Assessment - Achilles tendinopathy questionnaire (VISA-A) evaluates the clinical severity of Achilles tendinopathy. The aim of this study was to translate the VISA-A into French and to study the reliability and validity of this French version, the VISA-AF. The VISA-A was translated into French to produce the VISA-AF using a validated methodology in six steps. Thereafter, several psychometric properties of this French version such as test-retest reliability, internal consistency, construct validity and floor and ceiling effects were evaluated. Therefore, we recruited 116 subjects, distributed into 3 groups: pathological patients (n = 31), at-risk athletes (n = 63) and healthy people (n = 22). The final version of the VISA-AF was approved by an expert committee. On a scale ranging from 0 to 100, the average scores of the VISA-AF obtained were 59 (± 18) for the pathological group, 99 (± 1) for the healthy group and 94 (± 7) for the at-risk group. The VISA-AF shows excellent reliability, low correlations with the discriminant subscales of the SF-36 and moderate correlations with the convergent subscales of the SF-36. The French version of the VISA-A is equivalent to its original version and is a reliable and valid questionnaire for French-speaking patients with Achilles tendinopathy. Implication for Rehabilitation The VISA-AF questionnaire is a reliable translation of the original VISA-A, from English into French, which is one of the most widespread languages in the world. The VISA-AF questionnaire is now a valid instrument that can be used by clinicians and researchers to assess the severity of pain and disability of French-speaking subjects with Achilles tendinopathy. The VISA-AF is a questionnaire to assess the severity of Achilles tendinopathy symptoms but is not a diagnostic tool.

  14. Prevalence of vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous VISA among methicillin-resistant S. aureus with high vancomycin minimal inhibitory concentrations in Taiwan: A multicenter surveillance study, 2012-2013.

    PubMed

    Huang, Sung-Hsi; Chen, Yee-Chun; Chuang, Yin-Ching; Chiu, Sheng-Kang; Fung, Chang-Phone; Lu, Po-Liang; Wang, Lih-Shinn; Wu, Tsu-Lan; Wang, Jann-Tay

    2016-10-01

    Intermediate-resistance and heteroresistance to vancomycin in methicillin-resistant Staphylococcus aureus (MRSA) is reported worldwide. A surveillance study in 2003 showed that the prevalence rates of vancomycin-intermediate S. aureus (VISA) and heterogeneous VISA (hVISA) in Taiwan were 0.2% and 0.7%, respectively. This study aimed to investigate the updated prevalence of VISA and hVISA in Taiwan. MRSA isolates from sterile sites with minimal inhibitory concentrations (MICs) of 1 μg/mL or more to vancomycin were collected from 15 participating hospitals in Taiwan. Enrolled MRSA isolates were submitted to antimicrobial susceptibility testing, staphylococcal cassette chromosome mec (SCCmec) element typing, and multilocus sequence typing. Isolates with vancomycin MIC of 1 μg/mL or 2 μg/mL were screened for vancomycin heterogeneous resistance by Etest glycopeptide-resistance detection (GRD). Those with positive GRD screening results were then analyzed by modified population analysis profiling-area under the curve method for confirmation of vancomycin heteroresistance. Between 2012 and 2013, a total of 622 MRSA isolates from sterile sites with vancomycin MIC of 1 μg/mL or more were studied. The prevalence rates of hVISA and VISA among these isolates were 10.0% and 2.7%, respectively. The hVISA prevalence increased significantly compared to that in 2003. Compared with vancomycin-susceptible S. aureus, hVISA and VISA isolates were less susceptible to ciprofloxacin, clindamycin, daptomycin, gentamicin, rifampin, and trimethoprim/sulfamethoxazole, and are thus, more likely to have SCCmec II or III element. A twofold increase in either vancomycin or teicoplanin MIC doubled the probability of being hVISA. Growing hVISA prevalence was highly suspected. Longitudinal surveillance of this phenomenon and monitoring of its clinical impact are necessary. Copyright © 2015. Published by Elsevier B.V.

  15. Validation of the VISA-A questionnaire for Turkish language: the VISA-A-Tr study.

    PubMed

    Dogramaci, Yunus; Kalaci, Aydiner; Kücükkübas, Nigar; Inandi, Taceddin; Esen, Erdinc; Yanat, A Nedim

    2011-04-01

    To evaluate the validity and reliability of the Turkish version of the Victorian Institute of Sports Assessment-Achilles (VISA-A) questionnaire for patients with Achilles tendinopathy. Fifty-five patients with a diagnosis of Achilles tendinopathy and 55 healthy subjects were included in the study. VISA-A questionnaires were translated and culturally adapted into Turkish. The final Turkish version (VISA-A-Tr) was tested for reliability on healthy individuals and patients. Tests for internal consistency, validity and structure were performed on 55 patients. The VISA-A-Tr showed good test-retest reliability (Pearson's r=0.99, p<0.001). The patients with Achilles tendinopathy had a significantly lower score (p<0.001) than the healthy individuals. The VISA-A-Tr score correlated significantly with the Stanish tendon grading system (Spearman's r=-0.86; p<0.001). The VISA-A-Tr is a valid and reliable tool for evaluating the severity of Achilles tendinopathy.

  16. 8 CFR 245.18 - How can physicians (with approved Forms I-140) that are serving in medically underserved areas or...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... period following Service approval of a second preference employment-based immigrant visa petition. (b) Do... with Form I-485. The medical examination report shall be submitted with the documentary evidence noting... Form I-140 with a national interest waiver based upon full-time clinical practice in an underserved...

  17. 8 CFR 245.18 - How can physicians (with approved Forms I-140) that are serving in medically underserved areas or...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... period following Service approval of a second preference employment-based immigrant visa petition. (b) Do... with Form I-485. The medical examination report shall be submitted with the documentary evidence noting... Form I-140 with a national interest waiver based upon full-time clinical practice in an underserved...

  18. Rapid and easy detection of low-level resistance to vancomycin in methicillin-resistant Staphylococcus aureus by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

    PubMed

    Asakura, Kota; Azechi, Takuya; Sasano, Hiroshi; Matsui, Hidehito; Hanaki, Hideaki; Miyazaki, Motoyasu; Takata, Tohru; Sekine, Miwa; Takaku, Tomoiku; Ochiai, Tomonori; Komatsu, Norio; Shibayama, Keigo; Katayama, Yuki; Yahara, Koji

    2018-01-01

    Vancomycin-intermediately resistant Staphylococcus aureus (VISA) and heterogeneous VISA (hVISA) are associated with treatment failure. hVISA contains only a subpopulation of cells with increased minimal inhibitory concentrations, and its detection is problematic because it is classified as vancomycin-susceptible by standard susceptibility testing and the gold-standard method for its detection is impractical in clinical microbiology laboratories. Recently, a research group developed a machine-learning classifier to distinguish VISA and hVISA from vancomycin-susceptible S. aureus (VSSA) according to matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) data. Nonetheless, the sensitivity of hVISA classification was found to be 76%, and the program was not completely automated with a graphical user interface. Here, we developed a more accurate machine-learning classifier for discrimination of hVISA from VSSA and VISA among MRSA isolates in Japanese hospitals by means of MALDI-TOF MS data. The classifier showed 99% sensitivity of hVISA classification. Furthermore, we clarified the procedures for preparing samples and obtaining MALDI-TOF MS data and developed all-in-one software, hVISA Classifier, with a graphical user interface that automates the classification and is easy for medical workers to use; it is publicly available at https://github.com/bioprojects/hVISAclassifier. This system is useful and practical for screening MRSA isolates for the hVISA phenotype in clinical microbiology laboratories and thus should improve treatment of MRSA infections.

  19. Rapid and easy detection of low-level resistance to vancomycin in methicillin-resistant Staphylococcus aureus by matrix-assisted laser desorption ionization time-of-flight mass spectrometry

    PubMed Central

    Asakura, Kota; Azechi, Takuya; Sasano, Hiroshi; Matsui, Hidehito; Hanaki, Hideaki; Miyazaki, Motoyasu; Takata, Tohru; Sekine, Miwa; Takaku, Tomoiku; Ochiai, Tomonori; Komatsu, Norio; Shibayama, Keigo

    2018-01-01

    Vancomycin-intermediately resistant Staphylococcus aureus (VISA) and heterogeneous VISA (hVISA) are associated with treatment failure. hVISA contains only a subpopulation of cells with increased minimal inhibitory concentrations, and its detection is problematic because it is classified as vancomycin-susceptible by standard susceptibility testing and the gold-standard method for its detection is impractical in clinical microbiology laboratories. Recently, a research group developed a machine-learning classifier to distinguish VISA and hVISA from vancomycin-susceptible S. aureus (VSSA) according to matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) data. Nonetheless, the sensitivity of hVISA classification was found to be 76%, and the program was not completely automated with a graphical user interface. Here, we developed a more accurate machine-learning classifier for discrimination of hVISA from VSSA and VISA among MRSA isolates in Japanese hospitals by means of MALDI-TOF MS data. The classifier showed 99% sensitivity of hVISA classification. Furthermore, we clarified the procedures for preparing samples and obtaining MALDI-TOF MS data and developed all-in-one software, hVISA Classifier, with a graphical user interface that automates the classification and is easy for medical workers to use; it is publicly available at https://github.com/bioprojects/hVISAclassifier. This system is useful and practical for screening MRSA isolates for the hVISA phenotype in clinical microbiology laboratories and thus should improve treatment of MRSA infections. PMID:29522576

  20. 8 CFR 204.4 - Amerasian child of a United States citizen.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... IMMIGRANT PETITIONS Immigrant Visa Petitions § 204.4 Amerasian child of a United States citizen. (a..., Form I-360, Petition for Amerasian, Widow, or Special Immigrant. Any person filing the petition must...

  1. Information about the Current Strain of Clostridium difficile

    MedlinePlus

    ... rubs may not be as effective against spore-forming bacteria. Contact precautions Environmental cleaning and disinfection strategies. ... Detection of VISA/VRSA S.E.A.R.C.H. Labs Role in the Search and Containment of ...

  2. 47 CFR 1.1158 - Form of payment for regulatory fees.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Commission or by Visa, Mastercard, American Express or Discover credit cards only. The Commission discourages... submitted with an application in the wireless radio service) made by credit card or money order must be submitted with a completed FCC Form 159. Failure to accurately enter the credit card number and date of...

  3. 8 CFR 204.312 - Adjudication of the Form I-800A.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjudication of the Form I-800A. 204.312 Section 204.312 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRANT... Convention adoptee's application for admission with an immigrant visa or for adjustment of status: (A) The...

  4. iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA.

    PubMed

    Luo, Wei-Wei; Li, Shu; Li, Chen; Zheng, Zhou-Qin; Cao, Pan; Tong, Zhen; Lian, Huan; Wang, Su-Yun; Shu, Hong-Bing; Wang, Yan-Yi

    2017-11-01

    VISA (also known as MAVS, IPS-1 and Cardif) is an essential adaptor protein in innate immune response to RNA virus. The protein level of VISA is delicately regulated before and after viral infection to ensure the optimal activation and timely termination of innate antiviral response. It has been reported that several E3 ubiquitin ligases can mediate the degradation of VISA, but how the stability of VISA is maintained before and after viral infection remains enigmatic. In this study, we found that the ER-associated inactive rhomboid protein 2 (iRhom2) plays an essential role in mounting an efficient innate immune response to RNA virus by maintaining the stability of VISA through distinct mechanisms. In un-infected and early infected cells, iRhom2 mediates auto-ubiquitination and degradation of the E3 ubiquitin ligase RNF5 and impairs the assembly of VISA-RNF5-GP78 complexes, thereby antagonizes ER-associated degradation (ERAD) of VISA. In the late phase of viral infection, iRhom2 mediates proteasome-dependent degradation of the E3 ubiquitin ligase MARCH5 and impairs mitochondria-associated degradation (MAD) of VISA. Maintenance of VISA stability by iRhom2 ensures efficient innate antiviral response at the early phase of viral infection and ready for next round of response. Our findings suggest that iRhom2 acts as a checkpoint for the ERAD/MAD of VISA, which ensures proper innate immune response to RNA virus.

  5. iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA

    PubMed Central

    Luo, Wei-Wei; Li, Shu; Cao, Pan; Tong, Zhen; Lian, Huan; Wang, Su-Yun; Shu, Hong-Bing

    2017-01-01

    VISA (also known as MAVS, IPS-1 and Cardif) is an essential adaptor protein in innate immune response to RNA virus. The protein level of VISA is delicately regulated before and after viral infection to ensure the optimal activation and timely termination of innate antiviral response. It has been reported that several E3 ubiquitin ligases can mediate the degradation of VISA, but how the stability of VISA is maintained before and after viral infection remains enigmatic. In this study, we found that the ER-associated inactive rhomboid protein 2 (iRhom2) plays an essential role in mounting an efficient innate immune response to RNA virus by maintaining the stability of VISA through distinct mechanisms. In un-infected and early infected cells, iRhom2 mediates auto-ubiquitination and degradation of the E3 ubiquitin ligase RNF5 and impairs the assembly of VISA-RNF5-GP78 complexes, thereby antagonizes ER-associated degradation (ERAD) of VISA. In the late phase of viral infection, iRhom2 mediates proteasome-dependent degradation of the E3 ubiquitin ligase MARCH5 and impairs mitochondria-associated degradation (MAD) of VISA. Maintenance of VISA stability by iRhom2 ensures efficient innate antiviral response at the early phase of viral infection and ready for next round of response. Our findings suggest that iRhom2 acts as a checkpoint for the ERAD/MAD of VISA, which ensures proper innate immune response to RNA virus. PMID:29155878

  6. 22 CFR 42.66 - Medical examination.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.66 Medical examination. (a) Medical examination required of all applicants. Before the issuance of an immigrant visa, the consular officer shall...

  7. 22 CFR 42.65 - Supporting documents.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.65 Supporting documents. (a) Authority to... establish the alien's eligibility to receive an immigrant visa. All such documents submitted and other...

  8. 22 CFR 41.101 - Place of application.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.101 Place of application. (a) Application for regular visa made at jurisdictional consular office of alien's residence or physical presence...

  9. 22 CFR 41.101 - Place of application.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.101 Place of application. (a) Application for regular visa made at jurisdictional consular office of alien's residence or physical presence...

  10. 22 CFR 42.66 - Medical examination.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.66 Medical examination. (a) Medical examination required of all applicants. Before the issuance of an immigrant visa, the consular officer shall...

  11. 22 CFR 42.66 - Medical examination.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.66 Medical examination. (a) Medical examination required of all applicants. Before the issuance of an immigrant visa, the consular officer shall...

  12. 22 CFR 42.65 - Supporting documents.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.65 Supporting documents. (a) Authority to... establish the alien's eligibility to receive an immigrant visa. All such documents submitted and other...

  13. 76 FR 41861 - Voluntary Intermodal Sealift Agreement (VISA)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... DEPARTMENT OF TRANSPORTATION Maritime Administration Voluntary Intermodal Sealift Agreement (VISA) AGENCY: Maritime Administration, DOT. ACTION: Notice of open season for enrollment in the VISA program. Introduction The VISA program was established pursuant to section 708 of the Defense Production Act of 1950, as...

  14. 22 CFR 41.108 - Medical examination.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.108 Medical examination. (a) Requirements for medical examination. An applicant for a nonimmigrant visa shall be required to take a medical...

  15. 22 CFR 41.108 - Medical examination.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.108 Medical examination. (a) Requirements for medical examination. An applicant for a nonimmigrant visa shall be required to take a medical...

  16. 22 CFR 41.101 - Place of application.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.101 Place of application. (a) Application for regular visa made at jurisdictional consular office of alien's residence or physical presence...

  17. 22 CFR 41.108 - Medical examination.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.108 Medical examination. (a) Requirements for medical examination. An applicant for a nonimmigrant visa shall be required to take a medical...

  18. 22 CFR 41.103 - Filing an application.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.103 Filing an application. (a) Filing an application—(1) Filing of application required. Every alien seeking a nonimmigrant visa must...

  19. 22 CFR 42.65 - Supporting documents.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.65 Supporting documents. (a) Authority to... establish the alien's eligibility to receive an immigrant visa. All such documents submitted and other...

  20. 22 CFR 41.108 - Medical examination.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.108 Medical examination. (a) Requirements for medical examination. An applicant for a nonimmigrant visa shall be required to take a medical...

  1. 22 CFR 42.65 - Supporting documents.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.65 Supporting documents. (a) Authority to... establish the alien's eligibility to receive an immigrant visa. All such documents submitted and other...

  2. 22 CFR 41.101 - Place of application.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.101 Place of application. (a) Application for regular visa made at jurisdictional consular office of alien's residence or physical presence...

  3. 22 CFR 41.101 - Place of application.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.101 Place of application. (a) Application for regular visa made at jurisdictional consular office of alien's residence or physical presence...

  4. 22 CFR 42.66 - Medical examination.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.66 Medical examination. (a) Medical examination required of all applicants. Before the issuance of an immigrant visa, the consular officer shall...

  5. 75 FR 52594 - Voluntary Intermodal Sealift Agreement (VISA)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-26

    ... DEPARTMENT OF TRANSPORTATION Maritime Administration Voluntary Intermodal Sealift Agreement (VISA) AGENCY: Maritime Administration, DOT. ACTION: Notice of open season for enrollment in the VISA program. Introduction The VISA program was established pursuant to section 708 of the Defense Production Act of 1950, as...

  6. 77 FR 53963 - Voluntary Intermodal Sealift Agreement (VISA)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... DEPARTMENT OF TRANSPORTATION Maritime Administration Voluntary Intermodal Sealift Agreement (VISA) AGENCY: Maritime Administration, DOT. ACTION: Notice of open season for enrollment in the VISA program. Introduction The VISA program was established pursuant to section 708 of the Defense Production Act of 1950, as...

  7. 22 CFR 41.103 - Filing an application.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.103 Filing an application. (a) Filing an application—(1) Filing of application required. Every alien seeking a nonimmigrant visa must...

  8. 22 CFR 42.65 - Supporting documents.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.65 Supporting documents. (a) Authority to... establish the alien's eligibility to receive an immigrant visa. All such documents submitted and other...

  9. 22 CFR 41.103 - Filing an application.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.103 Filing an application. (a) Filing an application—(1) Filing of application required. Every alien seeking a nonimmigrant visa must...

  10. 22 CFR 42.66 - Medical examination.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.66 Medical examination. (a) Medical examination required of all applicants. Before the issuance of an immigrant visa, the consular officer shall...

  11. 22 CFR 41.108 - Medical examination.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.108 Medical examination. (a) Requirements for medical examination. An applicant for a nonimmigrant visa shall be required to take a medical...

  12. Identification of Low-Level Vancomycin Resistance in Staphylococcus aureus in the Era of Informatics.

    PubMed

    Ford, Bradley A

    2016-04-01

    Vancomycin-intermediateStaphylococcus aureus(VISA) and heteroresistant VISA (hVISA) are pathogens for which accurate antimicrobial susceptibility testing (AST) would rule out standard treatment with vancomycin. Unfortunately, AST for vancomycin is relatively slow and standard methods are unable to reliably detect VISA and hVISA. An article in this issue (C. A. Mather, B. J. Werth, S. Sivagnanam, D. J. SenGupta, and S. M. Butler-Wu, J Clin Microbiol 54:883-890, 2016, doi:http://dx.doi.org/10.1128/JCM.02428-15) describes a rapid whole-cell matrix-assisted laser desorption ionization-time of flight proxy susceptibility method that highlights current innovations and challenges with rapid AST, VISA/hVISA identification, and clinical bioinformatics. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  13. National Academy of Sciences: Helping Scientists Navigate & Troubleshoot Visa Issues

    NASA Astrophysics Data System (ADS)

    Bailey, Kathie

    2014-03-01

    The International Visitors Office (IVO) is a program operated by the Board on International Scientific Organizations of the National Academy of Sciences. The IVO serves as a resource on visa-related issues for scientists and students traveling to the United States for professional activities. The speaker will address visa issues for international scientists wishing to visit the United States, tips for trouble-shooting visa issues, and statistics on the current visa system.

  14. 22 CFR 41.105 - Supporting documents and fingerprinting.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Section 41.105 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.105 Supporting documents... receive a nonimmigrant visa. All documents and other evidence presented by the alien, including briefs...

  15. 22 CFR 42.31 - Family-sponsored immigrants.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ....31 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Classify Status of Alien Relative for Issuance of Immigrant Visa approved in accordance with INA 204 to... of a visa, is entitled to a derivative status corresponding to the classification and priority date...

  16. 22 CFR 41.12 - Classification symbols.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Classification of Nonimmigrants § 41.12 Classification symbols. A visa... appropriate visa symbol to show the classification of the alien. The symbol shall be inserted in the space...

  17. 22 CFR 42.31 - Family-sponsored immigrants.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ....31 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Classify Status of Alien Relative for Issuance of Immigrant Visa approved in accordance with INA 204 to... of a visa, is entitled to a derivative status corresponding to the classification and priority date...

  18. 22 CFR 42.67 - Execution of application, registration, and fingerprinting.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... fingerprinting. 42.67 Section 42.67 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.67 Execution of application, registration, and fingerprinting. (a) Execution of visa application—(1...

  19. 22 CFR 42.83 - Termination of registration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ....83 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Termination of registration. (a) Termination following failure of applicant to apply for visa. In accordance with INA 203(g), an alien's registration for an immigrant visa shall be terminated if, within one year...

  20. 22 CFR 41.105 - Supporting documents and fingerprinting.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 41.105 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.105 Supporting documents... receive a nonimmigrant visa. All documents and other evidence presented by the alien, including briefs...

  1. 22 CFR 41.12 - Classification symbols.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Classification of Nonimmigrants § 41.12 Classification symbols. A visa... appropriate visa symbol to show the classification of the alien. The symbol shall be inserted in the space...

  2. 22 CFR 42.83 - Termination of registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....83 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Termination of registration. (a) Termination following failure of applicant to apply for visa. In accordance with INA 203(g), an alien's registration for an immigrant visa shall be terminated if, within one year...

  3. 22 CFR 42.83 - Termination of registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....83 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Termination of registration. (a) Termination following failure of applicant to apply for visa. In accordance with INA 203(g), an alien's registration for an immigrant visa shall be terminated if, within one year...

  4. 22 CFR 42.31 - Family-sponsored immigrants.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....31 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Classify Status of Alien Relative for Issuance of Immigrant Visa approved in accordance with INA 204 to... of a visa, is entitled to a derivative status corresponding to the classification and priority date...

  5. 22 CFR 41.105 - Supporting documents and fingerprinting.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Section 41.105 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.105 Supporting documents... receive a nonimmigrant visa. All documents and other evidence presented by the alien, including briefs...

  6. 22 CFR 41.105 - Supporting documents and fingerprinting.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Section 41.105 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.105 Supporting documents... receive a nonimmigrant visa. All documents and other evidence presented by the alien, including briefs...

  7. 22 CFR 41.105 - Supporting documents and fingerprinting.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 41.105 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.105 Supporting documents... receive a nonimmigrant visa. All documents and other evidence presented by the alien, including briefs...

  8. 22 CFR 42.83 - Termination of registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ....83 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Termination of registration. (a) Termination following failure of applicant to apply for visa. In accordance with INA 203(g), an alien's registration for an immigrant visa shall be terminated if, within one year...

  9. 22 CFR 41.12 - Classification symbols.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Classification of Nonimmigrants § 41.12 Classification symbols. A visa... appropriate visa symbol to show the classification of the alien. The symbol shall be inserted in the space...

  10. 22 CFR 42.31 - Family-sponsored immigrants.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ....31 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Classify Status of Alien Relative for Issuance of Immigrant Visa approved in accordance with INA 204 to... of a visa, is entitled to a derivative status corresponding to the classification and priority date...

  11. 22 CFR 42.67 - Execution of application, registration, and fingerprinting.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... fingerprinting. 42.67 Section 42.67 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.67 Execution of application, registration, and fingerprinting. (a) Execution of visa application—(1...

  12. 22 CFR 42.67 - Execution of application, registration, and fingerprinting.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... fingerprinting. 42.67 Section 42.67 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.67 Execution of application, registration, and fingerprinting. (a) Execution of visa application—(1...

  13. 22 CFR 42.67 - Execution of application, registration, and fingerprinting.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... fingerprinting. 42.67 Section 42.67 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.67 Execution of application, registration, and fingerprinting. (a) Execution of visa application—(1...

  14. 22 CFR 42.83 - Termination of registration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ....83 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... Termination of registration. (a) Termination following failure of applicant to apply for visa. In accordance with INA 203(g), an alien's registration for an immigrant visa shall be terminated if, within one year...

  15. 75 FR 81204 - Notice of Public Information Collection Requirements Submitted to OMB for Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-27

    ...: OMB Number: OMB 0412-New. Form Number: N/A. Title: USAID Visa Compliance System (VCS). Type of... objectives by supporting: Economic growth, agriculture and trade; global health; and democracy conflict...

  16. 22 CFR 42.61 - Place of application.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.61 Place of application. (a) Alien to apply... an immigrant visa shall make application at the consular office having jurisdiction over the alien's...

  17. 22 CFR 41.83 - Certain witnesses and informants.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 41.83 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... consular officer has received verification from the Department of State, Visa Office, that: (A) in the case... at the time of verification. (b) Certification of S visa status. The certification of status under...

  18. 22 CFR 42.61 - Place of application.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.61 Place of application. (a) Alien to apply... an immigrant visa shall make application at the consular office having jurisdiction over the alien's...

  19. 22 CFR 42.61 - Place of application.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.61 Place of application. (a) Alien to apply... an immigrant visa shall make application at the consular office having jurisdiction over the alien's...

  20. 22 CFR 41.83 - Certain witnesses and informants.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 41.83 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... consular officer has received verification from the Department of State, Visa Office, that: (A) in the case... at the time of verification. (b) Certification of S visa status. The certification of status under...

  1. 22 CFR 41.83 - Certain witnesses and informants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 41.83 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... consular officer has received verification from the Department of State, Visa Office, that: (A) in the case... at the time of verification. (b) Certification of S visa status. The certification of status under...

  2. 22 CFR 41.83 - Certain witnesses and informants.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 41.83 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... consular officer has received verification from the Department of State, Visa Office, that: (A) in the case... at the time of verification. (b) Certification of S visa status. The certification of status under...

  3. 22 CFR 42.61 - Place of application.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.61 Place of application. (a) Alien to apply... an immigrant visa shall make application at the consular office having jurisdiction over the alien's...

  4. 22 CFR 41.83 - Certain witnesses and informants.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 41.83 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... consular officer has received verification from the Department of State, Visa Office, that: (A) in the case... at the time of verification. (b) Certification of S visa status. The certification of status under...

  5. 22 CFR 42.61 - Place of application.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.61 Place of application. (a) Alien to apply... an immigrant visa shall make application at the consular office having jurisdiction over the alien's...

  6. Change in visa status amongst Mandaean refugees: relationship to psychological symptoms and living difficulties.

    PubMed

    Nickerson, Angela; Steel, Zachary; Bryant, Richard; Brooks, Robert; Silove, Derrick

    2011-05-15

    Policies of deterrence, including the use of detention and temporary visas, have been widely implemented to dissuade asylum seekers from seeking protection in Western countries. The present study examined the impact of visa status change on the mental health of 97 Mandaean refugees resettled in Australia. At the time of the first survey (2004), 68 (70%) participants held temporary protection visas (TPVs) and 29 (30%) held permanent residency (PR) status, whereas by the second survey (2007), 97 (100%) participants held PR status. We tested a meditational model to determine whether the relationship between change in visa status and change in psychological symptoms was mediated by change in living difficulties associated with the visa categories. The conversion of visa status from TPV to PR status was associated with significant improvements in PTSD and depression symptoms, and increases in mental health-related quality of life (MHR-QOL). The relationship between change in visa status and reduced PTSD and depression symptoms was mediated by reductions in living difficulties. In contrast, the relationship between change in visa status and increased MHR-QOL was not mediated by changes in living difficulties. These results suggest that restriction of rights and access to services related to visa status negatively affect the mental health of refugees. Implications for government policies regarding refugees are discussed. Copyright © 2010. Published by Elsevier Ireland Ltd.

  7. 45 CFR 50.7 - Personal hardship, persecution and visa extension considerations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Personal hardship, persecution and visa extension... Personal hardship, persecution and visa extension considerations. (a) It is not within the Department's... not responsible for considering requests to extend visas. (c) Inquiries concerning the above should be...

  8. 22 CFR 41.102 - Personal appearance of applicant.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Section 41.102 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.102 Personal appearance of... (b) or (c) of this section, each applicant for a nonimmigrant visa must personally appear before and...

  9. 22 CFR 42.62 - Personal appearance and interview of applicant.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... 42.62 Section 42.62 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.62 Personal... alien applying for an immigrant visa, including an alien whose application is executed by another person...

  10. 22 CFR 42.53 - Priority date of individual applicants.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Section 42.53 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... individual applicants. (a) Preference applicant. The priority date of a preference visa applicant under INA... principal alien, whether or not named in the immigrant visa application of the principal alien. A child born...

  11. 45 CFR 50.7 - Personal hardship, persecution and visa extension considerations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Personal hardship, persecution and visa extension... Personal hardship, persecution and visa extension considerations. (a) It is not within the Department's... not responsible for considering requests to extend visas. (c) Inquiries concerning the above should be...

  12. 22 CFR 41.54 - Intracompany transferees (executives, managers, and specialists).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., and specialists). 41.54 Section 41.54 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41... petition by DHS does not establish that the alien is eligible to receive a nonimmigrant visa. (c) Validity...

  13. 22 CFR 40.67 - Student visa abusers.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Student visa abusers. 40.67 Section 40.67 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH NONIMMIGRANTS AND IMMIGRANTS... Student visa abusers. An alien ineligible under the provisions of INA 212(a)(6)(G) shall not be issued a...

  14. 14 CFR 1260.63 - Customs clearance and visas.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Customs clearance and visas. 1260.63 Section 1260.63 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GRANTS AND COOPERATIVE AGREEMENTS General Special Conditions § 1260.63 Customs clearance and visas. Customs Clearance and Visas (For...

  15. 22 CFR 42.53 - Priority date of individual applicants.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 42.53 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... individual applicants. (a) Preference applicant. The priority date of a preference visa applicant under INA... principal alien, whether or not named in the immigrant visa application of the principal alien. A child born...

  16. 22 CFR 42.53 - Priority date of individual applicants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 42.53 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... individual applicants. (a) Preference applicant. The priority date of a preference visa applicant under INA... principal alien, whether or not named in the immigrant visa application of the principal alien. A child born...

  17. 22 CFR 41.56 - Athletes, artists and entertainers.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Section 41.56 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.56 Athletes, artists and... join the principal alien. (b) Approval of visa. The approval of a petition by DHS does not establish...

  18. 14 CFR 1260.63 - Customs clearance and visas.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Customs clearance and visas. 1260.63 Section 1260.63 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GRANTS AND COOPERATIVE AGREEMENTS General Special Conditions § 1260.63 Customs clearance and visas. Customs Clearance and Visas (For...

  19. 22 CFR 41.102 - Personal appearance of applicant.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Section 41.102 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.102 Personal appearance of... (b) or (c) of this section, each applicant for a nonimmigrant visa must personally appear before and...

  20. 78 FR 73233 - 60-Day Notice of Proposed Information Collection: Online Application for Nonimmigrant Visa

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-05

    ... Application for Nonimmigrant Visa AGENCY: Department of State. ACTION: Notice of request for public comment...: Title of Information Collection: Online Application for Nonimmigrant Visa OMB Control Number: 1405-0182...: DS-160 Respondents: All Nonimmigrant Visa Applicants Estimated Number of Respondents: 11,100,276...

  1. 22 CFR 41.56 - Athletes, artists and entertainers.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Section 41.56 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.56 Athletes, artists and... join the principal alien. (b) Approval of visa. The approval of a petition by DHS does not establish...

  2. 22 CFR 41.56 - Athletes, artists and entertainers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 41.56 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.56 Athletes, artists and... join the principal alien. (b) Approval of visa. The approval of a petition by DHS does not establish...

  3. 22 CFR 41.56 - Athletes, artists and entertainers.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 41.56 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.56 Athletes, artists and... join the principal alien. (b) Approval of visa. The approval of a petition by DHS does not establish...

  4. 22 CFR 42.32 - Employment-based preference immigrants.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 42.32 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... employment-based immigrants in a fiscal year shall be allotted visas as indicated below. (a) First preference... immigrant, if not otherwise entitled to an immigrant status and the immediate issuance of a visa, is...

  5. 45 CFR 50.7 - Personal hardship, persecution and visa extension considerations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Personal hardship, persecution and visa extension... Personal hardship, persecution and visa extension considerations. (a) It is not within the Department's... not responsible for considering requests to extend visas. (c) Inquiries concerning the above should be...

  6. 22 CFR 42.32 - Employment-based preference immigrants.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Section 42.32 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... employment-based immigrants in a fiscal year shall be allotted visas as indicated below. (a) First preference... immigrant, if not otherwise entitled to an immigrant status and the immediate issuance of a visa, is...

  7. 14 CFR 1260.63 - Customs clearance and visas.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Customs clearance and visas. 1260.63 Section 1260.63 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GRANTS AND COOPERATIVE AGREEMENTS General Special Conditions § 1260.63 Customs clearance and visas. Customs Clearance and Visas (For...

  8. 22 CFR 40.67 - Student visa abusers.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Student visa abusers. 40.67 Section 40.67 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH NONIMMIGRANTS AND IMMIGRANTS... Student visa abusers. An alien ineligible under the provisions of INA 212(a)(6)(G) shall not be issued a...

  9. 22 CFR 42.32 - Employment-based preference immigrants.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Section 42.32 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... employment-based immigrants in a fiscal year shall be allotted visas as indicated below. (a) First preference... immigrant, if not otherwise entitled to an immigrant status and the immediate issuance of a visa, is...

  10. 45 CFR 50.7 - Personal hardship, persecution and visa extension considerations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Personal hardship, persecution and visa extension... Personal hardship, persecution and visa extension considerations. (a) It is not within the Department's... not responsible for considering requests to extend visas. (c) Inquiries concerning the above should be...

  11. 22 CFR 40.67 - Student visa abusers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Student visa abusers. 40.67 Section 40.67 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH NONIMMIGRANTS AND IMMIGRANTS... Student visa abusers. An alien ineligible under the provisions of INA 212(a)(6)(G) shall not be issued a...

  12. 14 CFR 1260.63 - Customs clearance and visas.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Customs clearance and visas. 1260.63 Section 1260.63 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GRANTS AND COOPERATIVE AGREEMENTS General Special Conditions § 1260.63 Customs clearance and visas. Customs Clearance and Visas (For...

  13. 22 CFR 41.56 - Athletes, artists and entertainers.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Section 41.56 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.56 Athletes, artists and... join the principal alien. (b) Approval of visa. The approval of a petition by DHS does not establish...

  14. 22 CFR 42.62 - Personal appearance and interview of applicant.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    .... 42.62 Section 42.62 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.62 Personal... alien applying for an immigrant visa, including an alien whose application is executed by another person...

  15. 22 CFR 40.67 - Student visa abusers.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Student visa abusers. 40.67 Section 40.67 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH NONIMMIGRANTS AND IMMIGRANTS... Student visa abusers. An alien ineligible under the provisions of INA 212(a)(6)(G) shall not be issued a...

  16. 22 CFR 42.53 - Priority date of individual applicants.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Section 42.53 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... individual applicants. (a) Preference applicant. The priority date of a preference visa applicant under INA... principal alien, whether or not named in the immigrant visa application of the principal alien. A child born...

  17. 22 CFR 42.62 - Personal appearance and interview of applicant.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... 42.62 Section 42.62 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.62 Personal... alien applying for an immigrant visa, including an alien whose application is executed by another person...

  18. 22 CFR 42.53 - Priority date of individual applicants.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Section 42.53 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... individual applicants. (a) Preference applicant. The priority date of a preference visa applicant under INA... principal alien, whether or not named in the immigrant visa application of the principal alien. A child born...

  19. 22 CFR 41.102 - Personal appearance of applicant.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Section 41.102 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.102 Personal appearance of... (b) or (c) of this section, each applicant for a nonimmigrant visa must personally appear before and...

  20. 22 CFR 41.102 - Personal appearance of applicant.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 41.102 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.102 Personal appearance of... (b) or (c) of this section, each applicant for a nonimmigrant visa must personally appear before and...

  1. 45 CFR 50.7 - Personal hardship, persecution and visa extension considerations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Personal hardship, persecution and visa extension... Personal hardship, persecution and visa extension considerations. (a) It is not within the Department's... not responsible for considering requests to extend visas. (c) Inquiries concerning the above should be...

  2. 22 CFR 42.32 - Employment-based preference immigrants.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Section 42.32 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... employment-based immigrants in a fiscal year shall be allotted visas as indicated below. (a) First preference... immigrant, if not otherwise entitled to an immigrant status and the immediate issuance of a visa, is...

  3. 22 CFR 40.67 - Student visa abusers.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Student visa abusers. 40.67 Section 40.67 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH NONIMMIGRANTS AND IMMIGRANTS... Student visa abusers. An alien ineligible under the provisions of INA 212(a)(6)(G) shall not be issued a...

  4. 19 CFR 142.11 - Entry summary form.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Entry summary form. 142.11 Section 142.11 Customs... (CONTINUED) ENTRY PROCESS Entry Summary Documentation § 142.11 Entry summary form. (a) Customs Form 7501. The entry summary shall be on Customs Form 7501 unless a different form is prescribed elsewhere in this...

  5. Delayed Workforce Entry and High Emigration Rates for Recent Canadian Radiation Oncology Graduates.

    PubMed

    Loewen, Shaun K; Halperin, Ross; Lefresne, Shilo; Trotter, Theresa; Stuckless, Teri; Brundage, Michael

    2015-10-01

    To determine the employment status and location of recent Canadian radiation oncology (RO) graduates and to identify current workforce entry trends. A fill-in-the-blank spreadsheet was distributed to all RO program directors in December 2013 and June 2014, requesting the employment status and location of their graduates over the last 3 years. Visa trainee graduates were excluded. Response rate from program directors was 100% for both survey administrations. Of 101 graduates identified, 99 (98%) had known employment status and location. In the December survey, 5 2013 graduates (16%), 17 2012 graduates (59%), and 18 2011 graduates (75%) had permanent staff employment. Six months later, 5 2014 graduates (29%), 15 2013 graduates (48%), 24 2012 graduates (83%), and 21 2011 graduates (88%) had secured staff positions. Fellowships and temporary locums were common for those without staff employment. The proportion of graduates with staff positions abroad increased from 22% to 26% 6 months later. Workforce entry for most RO graduates was delayed but showed steady improvement with longer time after graduation. High emigration rates for jobs abroad signify domestic employment challenges for newly certified, Canadian-trained radiation oncologists. Coordination on a national level is required to address and regulate radiation oncologist supply and demand disequilibrium in Canada. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. 8 CFR 1245.18 - How can physicians (with approved Forms I-140) that are serving in medically underserved areas or...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... employment-based immigrant visa petition. (b) Do alien physicians have special time-related requirements for... shall be submitted with the documentary evidence noting the physician's completion of the required years...) Once the Service has approved an alien physician's Form I-140 with a national interest waiver based...

  7. 8 CFR 1245.18 - How can physicians (with approved Forms I-140) that are serving in medically underserved areas or...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... employment-based immigrant visa petition. (b) Do alien physicians have special time-related requirements for... shall be submitted with the documentary evidence noting the physician's completion of the required years...) Once the Service has approved an alien physician's Form I-140 with a national interest waiver based...

  8. 8 CFR 1245.18 - How can physicians (with approved Forms I-140) that are serving in medically underserved areas or...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... employment-based immigrant visa petition. (b) Do alien physicians have special time-related requirements for... shall be submitted with the documentary evidence noting the physician's completion of the required years...) Once the Service has approved an alien physician's Form I-140 with a national interest waiver based...

  9. 8 CFR 1245.18 - How can physicians (with approved Forms I-140) that are serving in medically underserved areas or...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... employment-based immigrant visa petition. (b) Do alien physicians have special time-related requirements for... shall be submitted with the documentary evidence noting the physician's completion of the required years...) Once the Service has approved an alien physician's Form I-140 with a national interest waiver based...

  10. 8 CFR 1245.18 - How can physicians (with approved Forms I-140) that are serving in medically underserved areas or...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... employment-based immigrant visa petition. (b) Do alien physicians have special time-related requirements for... shall be submitted with the documentary evidence noting the physician's completion of the required years...) Once the Service has approved an alien physician's Form I-140 with a national interest waiver based...

  11. 76 FR 44349 - Agency Information Collection Activities: Arrival and Departure Record (Forms I-94 and I-94W) and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-25

    ... Activities: Arrival and Departure Record (Forms I-94 and I-94W) and Electronic System for Travel... I-94W (Nonimmigrant Visa Waiver Arrival/Departure), and the Electronic System for Travel... points: (1) Evaluate whether the proposed collection of information is necessary for the proper...

  12. 22 CFR 42.1 - Aliens not required to obtain immigrant visas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Aliens not required to obtain immigrant visas... Immigrants § 42.1 Aliens not required to obtain immigrant visas. An immigrant within any of the following categories is not required to obtain an immigrant visa: (a) Aliens lawfully admitted for permanent residence...

  13. 22 CFR 42.1 - Aliens not required to obtain immigrant visas.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Aliens not required to obtain immigrant visas... Immigrants § 42.1 Aliens not required to obtain immigrant visas. An immigrant within any of the following categories is not required to obtain an immigrant visa: (a) Aliens lawfully admitted for permanent residence...

  14. 22 CFR 42.1 - Aliens not required to obtain immigrant visas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Aliens not required to obtain immigrant visas... Immigrants § 42.1 Aliens not required to obtain immigrant visas. An immigrant within any of the following categories is not required to obtain an immigrant visa: (a) Aliens lawfully admitted for permanent residence...

  15. 22 CFR 42.1 - Aliens not required to obtain immigrant visas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Aliens not required to obtain immigrant visas... Immigrants § 42.1 Aliens not required to obtain immigrant visas. An immigrant within any of the following categories is not required to obtain an immigrant visa: (a) Aliens lawfully admitted for permanent residence...

  16. 22 CFR 42.1 - Aliens not required to obtain immigrant visas.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Aliens not required to obtain immigrant visas... Immigrants § 42.1 Aliens not required to obtain immigrant visas. An immigrant within any of the following categories is not required to obtain an immigrant visa: (a) Aliens lawfully admitted for permanent residence...

  17. 77 FR 74490 - Implementation of Immigrant Visa DHS Domestic Processing Fee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-14

    ... Docket No. USCIS-2009-0033] RIN 1615-ZB13 Implementation of Immigrant Visa DHS Domestic Processing Fee... will begin to collect a $165 Immigrant Visa DHS Domestic Processing Fee (USCIS Immigrant Fee) from individuals who have been issued immigrant visas by the U.S. Department of State (DOS) and are applying for...

  18. 22 CFR 41.62 - Exchange visitors.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND... to SEVIS or ISEAS prior to the issuance of a J-1 or J-2 visa. Evidence of the payment of any... Consular Database or direct access to SEVIS. Upon issuance of a J-1 or J-2 visa, notification of such...

  19. 22 CFR 41.21 - Foreign Officials-General.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION...)(15)(A)(iii), 101(a)(15)(G)(v), and 212(d)(8), and in the definition of the NATO-7 visa symbol, means... the NATO-1 through NATO-5 visa symbols, means the spouse and unmarried sons and daughters, whether by...

  20. 78 FR 23623 - 60-Day Notice of Proposed Information Collection: Nonimmigrant Fiancé(e) Visa Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ...: Nonimmigrant Fianc[eacute](e) Visa Application ACTION: Notice of request for public comment. SUMMARY: The... Results page. Email: [email protected] . Mail: Chief, Legislation and Regulation Division, Visa... documents, to Sydney Taylor, Visa Services, U.S. Department of State, 2401 E Street NW., L-603, Washington...

  1. 22 CFR 41.84 - Victims of trafficking in persons.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Section 41.84 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... status under INA 101(a)(15)(T)(i). (b) Visa validity. A qualifying family member may apply for a nonimmigrant visa under INA(a)(15)(T)(ii) only during the period in which the principal applicant is in status...

  2. 48 CFR 52.222-29 - Notification of visa denial.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Notification of visa....222-29 Notification of visa denial. As prescribed in 22.810(g), insert the following clause: Notification of Visa Denial (JUN 2003) It is a violation of Executive Order 11246 for a Contractor to refuse to...

  3. 8 CFR 211.3 - Expiration of immigrant visa or other travel document.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Expiration of immigrant visa or other... REGULATIONS DOCUMENTARY REQUIREMENTS: IMMIGRANTS; WAIVERS § 211.3 Expiration of immigrant visa or other travel document. An immigrant visa, reentry permit, refugee travel document, or a permanent resident card shall be...

  4. 22 CFR 41.57 - International cultural exchange visitors and visitors under the Irish Peace Process Cultural and...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.57 International cultural exchange... a petition does not establish that the alien is eligible to receive a nonimmigrant visa. (3...

  5. 48 CFR 52.222-29 - Notification of visa denial.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Notification of visa....222-29 Notification of visa denial. As prescribed in 22.810(g), insert the following clause: Notification of Visa Denial (JUN 2003) It is a violation of Executive Order 11246 for a Contractor to refuse to...

  6. 22 CFR 41.32 - Nonresident alien Mexican border crossing identification cards; combined border crossing...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... identification cards; combined border crossing identification cards and B-1/B-2 visitor visas. 41.32 Section 41.32 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... crossing identification cards; combined border crossing identification cards and B-1/B-2 visitor visas. (a...

  7. 22 CFR 41.84 - Victims of trafficking in persons.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 41.84 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... status under INA 101(a)(15)(T)(i). (b) Visa validity. A qualifying family member may apply for a nonimmigrant visa under INA(a)(15)(T)(ii) only during the period in which the principal applicant is in status...

  8. 22 CFR 42.68 - Informal evaluation of family members if principal applicant precedes them.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... principal applicant precedes them. 42.68 Section 42.68 Foreign Relations DEPARTMENT OF STATE VISAS VISAS... Visas § 42.68 Informal evaluation of family members if principal applicant precedes them. (a) Preliminary determination of visa eligibility. If a principal applicant proposes to precede the family to the...

  9. 22 CFR 41.32 - Nonresident alien Mexican border crossing identification cards; combined border crossing...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... identification cards; combined border crossing identification cards and B-1/B-2 visitor visas. 41.32 Section 41.32 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... crossing identification cards; combined border crossing identification cards and B-1/B-2 visitor visas. (a...

  10. 19 CFR 10.23 - Standards, quotas, and visas.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Standards, quotas, and visas. 10.23 Section 10.23... Abroad with United States Components § 10.23 Standards, quotas, and visas. All requirements and... properties, quotas, and visas, apply to assembled articles eligible for the exemption in the same manner as...

  11. 19 CFR 10.23 - Standards, quotas, and visas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Standards, quotas, and visas. 10.23 Section 10.23... Abroad with United States Components § 10.23 Standards, quotas, and visas. All requirements and... properties, quotas, and visas, apply to assembled articles eligible for the exemption in the same manner as...

  12. 22 CFR 41.32 - Nonresident alien Mexican border crossing identification cards; combined border crossing...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... identification cards; combined border crossing identification cards and B-1/B-2 visitor visas. 41.32 Section 41.32 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... crossing identification cards; combined border crossing identification cards and B-1/B-2 visitor visas. (a...

  13. 22 CFR 41.59 - Professionals under the North American Free Trade Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Trade Agreement. 41.59 Section 41.59 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.59... classified and is accompanying or following to join the principal alien. (b) Visa validity. The period of...

  14. 22 CFR 42.68 - Informal evaluation of family members if principal applicant precedes them.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... principal applicant precedes them. 42.68 Section 42.68 Foreign Relations DEPARTMENT OF STATE VISAS VISAS... Visas § 42.68 Informal evaluation of family members if principal applicant precedes them. (a) Preliminary determination of visa eligibility. If a principal applicant proposes to precede the family to the...

  15. 48 CFR 52.222-29 - Notification of visa denial.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Notification of visa....222-29 Notification of visa denial. As prescribed in 22.810(g), insert the following clause: Notification of Visa Denial (JUN 2003) It is a violation of Executive Order 11246 for a Contractor to refuse to...

  16. 22 CFR 41.84 - Victims of trafficking in persons.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 41.84 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... status under INA 101(a)(15)(T)(i). (b) Visa validity. A qualifying family member may apply for a nonimmigrant visa under INA(a)(15)(T)(ii) only during the period in which the principal applicant is in status...

  17. 22 CFR 41.84 - Victims of trafficking in persons.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Section 41.84 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... status under INA 101(a)(15)(T)(i). (b) Visa validity. A qualifying family member may apply for a nonimmigrant visa under INA(a)(15)(T)(ii) only during the period in which the principal applicant is in status...

  18. 19 CFR 10.23 - Standards, quotas, and visas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Standards, quotas, and visas. 10.23 Section 10.23... Abroad with United States Components § 10.23 Standards, quotas, and visas. All requirements and... properties, quotas, and visas, apply to assembled articles eligible for the exemption in the same manner as...

  19. 22 CFR 41.21 - Foreign Officials-General.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION...)(15)(A)(iii), 101(a)(15)(G)(v), and 212(d)(8), and in the definition of the NATO-7 visa symbol, means... the NATO-1 through NATO-5 visa symbols, means the spouse and unmarried sons and daughters, whether by...

  20. 19 CFR 10.23 - Standards, quotas, and visas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Standards, quotas, and visas. 10.23 Section 10.23... Abroad with United States Components § 10.23 Standards, quotas, and visas. All requirements and... properties, quotas, and visas, apply to assembled articles eligible for the exemption in the same manner as...

  1. 22 CFR 41.57 - International cultural exchange visitors and visitors under the Irish Peace Process Cultural and...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.57 International cultural exchange... a petition does not establish that the alien is eligible to receive a nonimmigrant visa. (3...

  2. 14 CFR § 1260.63 - Customs clearance and visas.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Customs clearance and visas. § 1260.63... COOPERATIVE AGREEMENTS General Special Conditions § 1260.63 Customs clearance and visas. Customs Clearance and Visas (For grants or cooperative agreements with foreign organizations, this clause will be developed on...

  3. 8 CFR 211.3 - Expiration of immigrant visa or other travel document.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Expiration of immigrant visa or other... REGULATIONS DOCUMENTARY REQUIREMENTS: IMMIGRANTS; WAIVERS § 211.3 Expiration of immigrant visa or other travel document. An immigrant visa, reentry permit, refugee travel document, or a permanent resident card shall be...

  4. 22 CFR 41.57 - International cultural exchange visitors and visitors under the Irish Peace Process Cultural and...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.57 International cultural exchange... a petition does not establish that the alien is eligible to receive a nonimmigrant visa. (3...

  5. 22 CFR 41.59 - Professionals under the North American Free Trade Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Trade Agreement. 41.59 Section 41.59 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.59... classified and is accompanying or following to join the principal alien. (b) Visa validity. The period of...

  6. 31 CFR 560.505 - Importation of certain Iranian-origin services authorized; activities related to certain visa...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... services authorized; activities related to certain visa categories authorized. 560.505 Section 560.505...; activities related to certain visa categories authorized. (a) The importation of Iranian-origin services into... with that purpose. (b) Persons otherwise qualified for a non-immigrant visa under categories A-3 and G...

  7. 48 CFR 52.222-29 - Notification of visa denial.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Notification of visa....222-29 Notification of visa denial. As prescribed in 22.810(g), insert the following clause: Notification of Visa Denial (JUN 2003) It is a violation of Executive Order 11246 for a Contractor to refuse to...

  8. 22 CFR 41.21 - Foreign Officials-General.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION...)(15)(A)(iii), 101(a)(15)(G)(v), and 212(d)(8), and in the definition of the NATO-7 visa symbol, means... the NATO-1 through NATO-5 visa symbols, means the spouse and unmarried sons and daughters, whether by...

  9. 22 CFR 41.57 - International cultural exchange visitors and visitors under the Irish Peace Process Cultural and...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.57 International cultural exchange... a petition does not establish that the alien is eligible to receive a nonimmigrant visa. (3...

  10. 22 CFR 41.84 - Victims of trafficking in persons.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Section 41.84 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... status under INA 101(a)(15)(T)(i). (b) Visa validity. A qualifying family member may apply for a nonimmigrant visa under INA(a)(15)(T)(ii) only during the period in which the principal applicant is in status...

  11. 22 CFR 41.21 - Foreign Officials-General.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION...)(15)(A)(iii), 101(a)(15)(G)(v), and 212(d)(8), and in the definition of the NATO-7 visa symbol, means... the NATO-1 through NATO-5 visa symbols, means the spouse and unmarried sons and daughters, whether by...

  12. 22 CFR 41.62 - Exchange visitors.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND... to SEVIS or ISEAS prior to the issuance of a J-1 or J-2 visa. Evidence of the payment of any... Consular Database or direct access to SEVIS. Upon issuance of a J-1 or J-2 visa, notification of such...

  13. 31 CFR 560.505 - Importation of certain Iranian-origin services authorized; activities related to certain visa...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... services authorized; activities related to certain visa categories authorized. 560.505 Section 560.505...; activities related to certain visa categories authorized. (a) The importation of Iranian-origin services into... with that purpose. (b) Persons otherwise qualified for a non-immigrant visa under categories A-3 and G...

  14. 8 CFR 211.3 - Expiration of immigrant visa or other travel document.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Expiration of immigrant visa or other... REGULATIONS DOCUMENTARY REQUIREMENTS: IMMIGRANTS; WAIVERS § 211.3 Expiration of immigrant visa or other travel document. An immigrant visa, reentry permit, refugee travel document, or a permanent resident card shall be...

  15. 22 CFR 41.32 - Nonresident alien Mexican border crossing identification cards; combined border crossing...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... identification cards; combined border crossing identification cards and B-1/B-2 visitor visas. 41.32 Section 41.32 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... crossing identification cards; combined border crossing identification cards and B-1/B-2 visitor visas. (a...

  16. 22 CFR 42.68 - Informal evaluation of family members if principal applicant precedes them.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... principal applicant precedes them. 42.68 Section 42.68 Foreign Relations DEPARTMENT OF STATE VISAS VISAS... Visas § 42.68 Informal evaluation of family members if principal applicant precedes them. (a) Preliminary determination of visa eligibility. If a principal applicant proposes to precede the family to the...

  17. 31 CFR 560.505 - Importation of certain Iranian-origin services authorized; activities related to certain visa...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... services authorized; activities related to certain visa categories authorized. 560.505 Section 560.505...; activities related to certain visa categories authorized. (a) The importation of Iranian-origin services into... with that purpose. (b) Persons otherwise qualified for a non-immigrant visa under categories A-3 and G...

  18. 22 CFR 41.32 - Nonresident alien Mexican border crossing identification cards; combined border crossing...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... identification cards; combined border crossing identification cards and B-1/B-2 visitor visas. 41.32 Section 41.32 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE... crossing identification cards; combined border crossing identification cards and B-1/B-2 visitor visas. (a...

  19. 19 CFR 10.23 - Standards, quotas, and visas.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Standards, quotas, and visas. 10.23 Section 10.23... Abroad with United States Components § 10.23 Standards, quotas, and visas. All requirements and... properties, quotas, and visas, apply to assembled articles eligible for the exemption in the same manner as...

  20. 22 CFR 41.62 - Exchange visitors.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND... to SEVIS or ISEAS prior to the issuance of a J-1 or J-2 visa. Evidence of the payment of any... Consular Database or direct access to SEVIS. Upon issuance of a J-1 or J-2 visa, notification of such...

  1. 22 CFR 41.62 - Exchange visitors.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND... to SEVIS or ISEAS prior to the issuance of a J-1 or J-2 visa. Evidence of the payment of any... Consular Database or direct access to SEVIS. Upon issuance of a J-1 or J-2 visa, notification of such...

  2. 22 CFR 42.68 - Informal evaluation of family members if principal applicant precedes them.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... principal applicant precedes them. 42.68 Section 42.68 Foreign Relations DEPARTMENT OF STATE VISAS VISAS... Visas § 42.68 Informal evaluation of family members if principal applicant precedes them. (a) Preliminary determination of visa eligibility. If a principal applicant proposes to precede the family to the...

  3. 48 CFR 52.222-29 - Notification of visa denial.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Notification of visa....222-29 Notification of visa denial. As prescribed in 22.810(g), insert the following clause: Notification of Visa Denial (JUN 2003) It is a violation of Executive Order 11246 for a Contractor to refuse to...

  4. 22 CFR 41.59 - Professionals under the North American Free Trade Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Trade Agreement. 41.59 Section 41.59 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.59... classified and is accompanying or following to join the principal alien. (b) Visa validity. The period of...

  5. 22 CFR 41.62 - Exchange visitors.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND... to SEVIS or ISEAS prior to the issuance of a J-1 or J-2 visa. Evidence of the payment of any... Consular Database or direct access to SEVIS. Upon issuance of a J-1 or J-2 visa, notification of such...

  6. 22 CFR 41.21 - Foreign Officials-General.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION...)(15)(A)(iii), 101(a)(15)(G)(v), and 212(d)(8), and in the definition of the NATO-7 visa symbol, means... the NATO visa symbols, means the spouse and unmarried sons and daughters, whether by blood or adoption...

  7. 22 CFR 41.57 - International cultural exchange visitors and visitors under the Irish Peace Process Cultural and...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.57 International cultural exchange... a petition does not establish that the alien is eligible to receive a nonimmigrant visa. (3...

  8. The victorian institute of sports assessment - achilles questionnaire (visa-a) - a reliable tool for measuring achilles tendinopathy.

    PubMed

    Iversen, Jonas Vestergård; Bartels, Else Marie; Langberg, Henning

    2012-02-01

    Achilles tendinopathy (AT) is a common pathology and the aetiology is unknown. For valid and reliable assessment The Victorian Institute of Sports Assessment has designed a self-administered Achilles questionnaire, the VISA-A. The aim of the present study was to evaluate VISA-A as an outcome measure in patients with AT. A systematic search of the literature was conducted using MEDLINE, EMBASE, CINAHL, PEDro, Web of Science, and Cochrane Controlled trials to identify trials using VISA-A for patients with AT. This was followed by data mining and analysis of the obtained data. Twenty-six clinical trials containing 1336 individuals were included. Overall mean VISA-A scores ranged from 24 (severe AT) to 100 (healthy). Mean VISA-A scores in patients with AT ranged from 24 to 96.6. Healthy subjects scored a minimum of 96. Only two groups of participants from two different studies had a post-VISA-A score as high as healthy individuals, indicating full recovery of the AT. A VISA-A score lower than 24 is rarely attained in AT. Only few patients with AT reach an equivalent VISA-A score compared to uninjured healthy subjects following treatment. The VISA-A is a reliable tool when assessing AT patients, providing a good assessment of the actual condition from very poor, (score around 24) to excellent (a score of 90), which based on this systematic review and previous studies could be considered full recovery from AT.

  9. Cross-cultural adaptation of VISA-P score for patellar tendinopathy in Turkish population.

    PubMed

    Çelebi, Mehmet Mesut; Köse, Serdal Kenan; Akkaya, Zehra; Zergeroglu, Ali Murat

    2016-01-01

    VISA-P questionnaire assesses to severity of symptoms and treatment effects in athletes with patellar tendinopathy. The purpose of this study was to translated VISA-P questionnaire into Turkish language and to determine its validity and reliability. The English version of VISA-P questionnaire was translated into Turkish according to the internationally recommended guidelines. Test-retest reliability was determined on 89 participants with time interval 24 h. To determine validity of Turkish VISA-P, 31 (17 male, 14 female) healthy students, 34 (20 male, 14 female) patients with patellar tendinopathy (diagnosed by physical examination and ultrasonography) and 24 (16 male, 8 female) volleyball players (at risk populations) were completed VISA-P-Tr. Internal consistency was determined with Cronbach's alpha. Intraclass correlation coefficients (ICCs) were calculated to analyse test-retest reliability. To assessment of discrimination, VISA-P-Tr scores compared all groups using the Mann-Whitney-U test. The VISA-P-Tr questionnaire showed good test-retest reliability (The Cronbach's alpha was 0.79 and 0.78 respectively and ICC was 0.96). The VISA-P-Tr score (mean ± SD) were 93.7 ± 8.9 and 94.0 ± 8.1 for healthy students, 81.1 ± 13.7 and 80.7 ± 13.4 for volleyball players, 58.8 ± 12.1 and 58.5 ± 11.0 for athletes with patellar tendinopathy. The translated Turkish version of VISA-P has good internal consistency and good reliability and validity. Therefore VISA-P-Tr is useful to evaluate symptoms and follow the treatment effect in athletes with patellar tendinopathy.

  10. β-Lactam Combinations with Vancomycin Show Synergistic Activity against Vancomycin-Susceptible Staphylococcus aureus, Vancomycin-Intermediate S. aureus (VISA), and Heterogeneous VISA.

    PubMed

    Tran, Kieu-Nhi; Rybak, Michael J

    2018-06-01

    Increasing utilization of vancomycin due to the high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) infections has led to the emergence of vancomycin-intermediate S. aureus (VISA) and heterogeneous VISA (hVISA) strains. In vitro data suggest the potential for potent synergy between several beta-lactams and vancomycin. The objective of this study is to evaluate the synergy between beta-lactams and vancomycin against MRSA that is vancomycin susceptible, vancomycin-susceptible Staphylococcus aureus (VSSA), hVISA, and VISA. Fifty randomly selected clinical MRSA strains with various susceptibility levels to vancomycin were evaluated for vancomycin alone and vancomycin in combination with various concentrations of cefazolin (CFZ), cefepime (FEP), ceftaroline (CPT), and nafcillin (NAF). The potential for synergy was assessed by 24-h time-kill studies. Beta-lactams reduced vancomycin MIC values against all strains (4- to 16-fold reduction). In time-kill studies against MRSA, CFZ, FEP, CPT, and NAF all demonstrated similar degrees of killing at 24 h, and all showed synergistic activity with vancomycin against VSSA, hVISA, and VISA. Each of these combinations was also superior to any single agent against isolates of all three phenotypes, and each was bactericidal ( P < 0.001 for all comparisons). All single-agent exposures demonstrated no activity at 24 h. The combination of vancomycin and beta-lactams significantly improved antibacterial activity against VSSA, hVISA, and VISA strains compared to the activity of any agent alone, supporting the potential use of vancomycin-beta-lactam combination therapy in infections caused by MRSA. Further clinical research is warranted to investigate the synergy of vancomycin against these Staphylococcus strains. Copyright © 2018 American Society for Microbiology.

  11. Impact of Time to Appropriate Therapy on Mortality in Patients with Vancomycin-Intermediate Staphylococcus aureus Infection

    PubMed Central

    Warren, David K.; Kollef, Marin H.

    2016-01-01

    Despite the increasing incidence of vancomycin-intermediate Staphylococcus aureus (VISA) infections, few studies have examined the impact of delay in receipt of appropriate antimicrobial therapy on outcomes in VISA patients. We examined the effects of timing of appropriate antimicrobial therapy in a cohort of patients with sterile-site methicillin-resistant S. aureus (MRSA) and VISA infections. In this single-center, retrospective cohort study, we identified all patients with MRSA or VISA sterile-site infections from June 2009 to February 2015. Clinical outcomes were compared according to MRSA/VISA classification, demographics, comorbidities, and antimicrobial treatment. Thirty-day all-cause mortality was modeled with Kaplan-Meier curves. Multivariate logistic regression analysis (MVLRA) was used to determine odds ratios for mortality. We identified 354 patients with MRSA (n = 267) or VISA (n = 87) sterile-site infection. Fifty-five patients (15.5%) were nonsurvivors. Factors associated with mortality in MVLRA included pneumonia, unknown source of infection, acute physiology and chronic health evaluation (APACHE) II score, solid-organ malignancy, and admission from skilled care facilities. Time to appropriate antimicrobial therapy was not significantly associated with outcome. Presence of a VISA infection compared to that of a non-VISA S. aureus infection did not result in excess mortality. Linezolid use was a risk for mortality in patients with APACHE II scores of ≥14. Our results suggest that empirical vancomycin use in patients with VISA infections does not result in excess mortality. Future studies should (i) include larger numbers of patients with VISA infections to confirm the findings presented here and (ii) determine the optimal antibiotic therapy for critically ill patients with MRSA and VISA infections. PMID:27401565

  12. 76 FR 61776 - 60-Day Notice of Proposed Information Collection: DS-230, Application for Immigrant Visa and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ..., Application for Immigrant Visa and Alien Registration, OMB Number 1405- 0015 ACTION: Notice of request for... Immigrant Visa and Alien Registration. OMB Control Number: 1405-0015. Type of Request: Revision of a... collection: The DS-230 is used to determine the eligibility of aliens applying for immigrant visas that have...

  13. 22 CFR 40.205 - Applicant for immigrant visa under INA 203(c).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Applicant for immigrant visa under INA 203(c... NONIMMIGRANTS AND IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Failure to Comply with INA § 40.205 Applicant for immigrant visa under INA 203(c). An alien shall be ineligible to receive a visa...

  14. 22 CFR 41.81 - Fiancé(e) or spouse of a U.S. citizen and derivative children.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... derivative children. 41.81 Section 41.81 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF... other qualifications in order to receive a nonimmigrant visa, including the requirements of paragraph (d... that country, then at a consular post designated by the Deputy Assistant Secretary of State for Visa...

  15. 22 CFR 41.86 - Certain spouses and children of lawful permanent resident aliens.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... permanent resident aliens. 41.86 Section 41.86 Foreign Relations DEPARTMENT OF STATE VISAS VISAS... “remains pending”. For the purposes of this section, a visa application “remains pending” if the applicant has applied for an immigrant visa in accordance with the definition in part 40, § 40.1(l)(2) and the...

  16. 22 CFR 40.4 - Furnishing records and information from visa files for court proceedings.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Furnishing records and information from visa files for court proceedings. 40.4 Section 40.4 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS... Provisions § 40.4 Furnishing records and information from visa files for court proceedings. Upon receipt of a...

  17. 22 CFR 40.4 - Furnishing records and information from visa files for court proceedings.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Furnishing records and information from visa files for court proceedings. 40.4 Section 40.4 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS... Provisions § 40.4 Furnishing records and information from visa files for court proceedings. Upon receipt of a...

  18. 78 FR 51801 - 30-Day Notice of Proposed Information Collection: Application for A, G, or NATO Visa

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ...: Application for A, G, or NATO Visa ACTION: Notice of request for public comment and submission to OMB of... proposed collection instrument and supporting documents, to Sydney Taylor, Visa Services, U.S. Department... Visas OMB Control Number: 1405-0100 Type of Request: Extension of a Currently Approved Collection...

  19. 22 CFR 40.4 - Furnishing records and information from visa files for court proceedings.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Furnishing records and information from visa files for court proceedings. 40.4 Section 40.4 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS... Provisions § 40.4 Furnishing records and information from visa files for court proceedings. Upon receipt of a...

  20. 22 CFR 41.81 - Fiancé(e) or spouse of a U.S. citizen and derivative children.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... derivative children. 41.81 Section 41.81 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF... other qualifications in order to receive a nonimmigrant visa, including the requirements of paragraph (d... that country, then at a consular post designated by the Deputy Assistant Secretary of State for Visa...

  1. 22 CFR 41.81 - Fiancé(e) or spouse of a U.S. citizen and derivative children.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... derivative children. 41.81 Section 41.81 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF... other qualifications in order to receive a nonimmigrant visa, including the requirements of paragraph (d... that country, then at a consular post designated by the Deputy Assistant Secretary of State for Visa...

  2. 76 FR 10084 - 60-Day Notice of Proposed Information Collection: DS-3035, J-1 Visa Waiver Recommendation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ... Information Collection: DS-3035, J-1 Visa Waiver Recommendation Application ACTION: Notice of request for... accordance with the Paperwork Reduction Act of 1995. Title of Information Collection: J-1 Visa Waiver.... Respondents: J-1 visa holders applying for a waiver of the two-year foreign residence requirement. Estimated...

  3. 22 CFR 41.86 - Certain spouses and children of lawful permanent resident aliens.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... permanent resident aliens. 41.86 Section 41.86 Foreign Relations DEPARTMENT OF STATE VISAS VISAS... “remains pending”. For the purposes of this section, a visa application “remains pending” if the applicant has applied for an immigrant visa in accordance with the definition in part 40, § 40.1(l)(2) and the...

  4. 22 CFR 40.4 - Furnishing records and information from visa files for court proceedings.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Furnishing records and information from visa files for court proceedings. 40.4 Section 40.4 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS... Provisions § 40.4 Furnishing records and information from visa files for court proceedings. Upon receipt of a...

  5. 22 CFR 41.81 - Fiancé(e) or spouse of a U.S. citizen and derivative children.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... derivative children. 41.81 Section 41.81 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF... other qualifications in order to receive a nonimmigrant visa, including the requirements of paragraph (d... that country, then at a consular post designated by the Deputy Assistant Secretary of State for Visa...

  6. 22 CFR 41.81 - Fiancé(e) or spouse of a U.S. citizen and derivative children.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... derivative children. 41.81 Section 41.81 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF... other qualifications in order to receive a nonimmigrant visa, including the requirements of paragraph (d... that country, then at a consular post designated by the Deputy Assistant Secretary of State for Visa...

  7. THE VICTORIAN INSTITUTE OF SPORTS ASSESSMENT – ACHILLES QUESTIONNAIRE (VISA-A) – A RELIABLE TOOL FOR MEASURING ACHILLES TENDINOPATHY

    PubMed Central

    Bartels, Else Marie; Langberg, Henning

    2012-01-01

    Background: Achilles tendinopathy (AT) is a common pathology and the aetiology is unknown. For valid and reliable assessment The Victorian Institute of Sports Assessment has designed a self-administered Achilles questionnaire, the VISA-A. The aim of the present study was to evaluate VISA-A as an outcome measure in patients with AT. Methods: A systematic search of the literature was conducted using MEDLINE, EMBASE, CINAHL, PEDro, Web of Science, and Cochrane Controlled trials to identify trials using VISA-A for patients with AT. This was followed by data mining and analysis of the obtained data. Results: Twenty-six clinical trials containing 1336 individuals were included. Overall mean VISA-A scores ranged from 24 (severe AT) to 100 (healthy). Mean VISA-A scores in patients with AT ranged from 24 to 96.6. Healthy subjects scored a minimum of 96. Only two groups of participants from two different studies had a post-VISA-A score as high as healthy individuals, indicating full recovery of the AT. Conclusions: A VISA-A score lower than 24 is rarely attained in AT. Only few patients with AT reach an equivalent VISA-A score compared to uninjured healthy subjects following treatment. The VISA-A is a reliable tool when assessing AT patients, providing a good assessment of the actual condition from very poor, (score around 24) to excellent (a score of 90), which based on this systematic review and previous studies could be considered full recovery from AT. PMID:22319681

  8. Smurf2 negatively modulates RIG-I-dependent antiviral response by targeting VISA/MAVS for ubiquitination and degradation.

    PubMed

    Pan, Yu; Li, Rui; Meng, Jun-Ling; Mao, He-Ting; Zhang, Yu; Zhang, Jun

    2014-05-15

    VISA (also known as MAVS, Cardif, IPS-1) is the essential adaptor protein for virus-induced activation of IFN regulatory factors 3 and 7 and production of type I IFNs. Understanding the regulatory mechanisms for VISA will provide detailed insights into the positive or negative regulation of innate immune responses. In this study, we identified Smad ubiquitin regulatory factor (Smurf) 2, one of the Smad ubiquitin regulator factor proteins, as an important negative regulator of virus-triggered type I IFN signaling, which targets at the VISA level. Overexpression of Smurf2 inhibits virus-induced IFN-β and IFN-stimulated response element activation. The E3 ligase defective mutant Smurf2/C716A loses the ability to suppress virus-induced type I IFN signaling, suggesting that the negative regulation is dependent on the ubiquitin E3 ligase activity of Smurf2. Further studies demonstrated that Smurf2 interacted with VISA and targeted VISA for K48-linked ubiquitination, which promoted the degradation of VISA. Consistently, knockout or knockdown of Smurf2 expression therefore promoted antiviral signaling, which was correlated with the increase in protein stability of VISA. Our findings suggest that Smurf2 is an important nonredundant negative regulator of virus-triggered type I IFN signaling by targeting VISA for K48-linked ubiquitination and degradation.

  9. 22 CFR 41.3 - Waiver by joint action of consular and immigration officers of passport and/or visa requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... immigration officers of passport and/or visa requirements. 41.3 Section 41.3 Foreign Relations DEPARTMENT OF... Passport and Visas Not Required for Certain Nonimmigrants § 41.3 Waiver by joint action of consular and immigration officers of passport and/or visa requirements. Under the authority of INA 212(d)(4), the...

  10. 22 CFR 41.3 - Waiver by joint action of consular and immigration officers of passport and/or visa requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... immigration officers of passport and/or visa requirements. 41.3 Section 41.3 Foreign Relations DEPARTMENT OF... Passport and Visas Not Required for Certain Nonimmigrants § 41.3 Waiver by joint action of consular and immigration officers of passport and/or visa requirements. Under the authority of INA 212(d)(4), the...

  11. 22 CFR 41.3 - Waiver by joint action of consular and immigration officers of passport and/or visa requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... immigration officers of passport and/or visa requirements. 41.3 Section 41.3 Foreign Relations DEPARTMENT OF... Passport and Visas Not Required for Certain Nonimmigrants § 41.3 Waiver by joint action of consular and immigration officers of passport and/or visa requirements. Under the authority of INA 212(d)(4), the...

  12. 22 CFR 41.3 - Waiver by joint action of consular and immigration officers of passport and/or visa requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... immigration officers of passport and/or visa requirements. 41.3 Section 41.3 Foreign Relations DEPARTMENT OF... Passport and Visas Not Required for Certain Nonimmigrants § 41.3 Waiver by joint action of consular and immigration officers of passport and/or visa requirements. Under the authority of INA 212(d)(4), the...

  13. 22 CFR 41.3 - Waiver by joint action of consular and immigration officers of passport and/or visa requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... immigration officers of passport and/or visa requirements. 41.3 Section 41.3 Foreign Relations DEPARTMENT OF... Passport and Visas Not Required for Certain Nonimmigrants § 41.3 Waiver by joint action of consular and immigration officers of passport and/or visa requirements. Under the authority of INA 212(d)(4), the...

  14. 78 FR 32696 - 60-Day Notice of Proposed Information Collection: Application for A, G, or NATO Visa

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ...: Application for A, G, or NATO Visa ACTION: Notice of request for public comment. SUMMARY: The Department of... Regulations Division, Visa Services Office--DS-1648, 2401 E Street NW., Washington, DC 20520- 30106. You must... instrument and supporting documents, to Sydney Taylor, Visa Services, U.S. Department of State, 2401 E Street...

  15. Permanent Visas and Temporary Jobs: Evidence from Postdoctoral Participation of Foreign PhDs in the United States

    ERIC Educational Resources Information Center

    Lan, Xiaohuan

    2012-01-01

    About 75 percent of U.S.-trained, noncitizen PhDs in science and engineering work in the United States after graduation, and 54 percent of those who stay take postdoctoral positions. The probability of postdoctoral participation is substantially higher for temporary visa holders than for permanent visa holders because of visa-related restrictions…

  16. VISA is an adapter protein required for virus-triggered IFN-beta signaling.

    PubMed

    Xu, Liang-Guo; Wang, Yan-Yi; Han, Ke-Jun; Li, Lian-Yun; Zhai, Zhonghe; Shu, Hong-Bing

    2005-09-16

    Viral infection or stimulation of TLR3 triggers signaling cascades, leading to activation of the transcription factors IRF-3 and NF-kappaB, which collaborate to induce transcription of type I interferon (IFN) genes. In this study, we identified a protein termed VISA (for virus-induced signaling adaptor) as a critical component in the IFN-beta signaling pathways. VISA recruits IRF-3 to the cytoplasmic viral dsRNA sensor RIG-I. Depletion of VISA inhibits virus-triggered and RIG-I-mediated activation of IRF-3, NF-kappaB, and the IFN-beta promoter, suggesting that VISA plays a central role in virus-triggered TLR3-independent IFN-beta signaling. Our data also indicate that VISA interacts with TRIF and TRAF6 and mediates bifurcation of the TLR3-triggered NF-kappaB and IRF-3 activation pathways. These findings suggest that VISA is critically involved in both virus-triggered TLR3-independent and TLR3-mediated antiviral IFN signaling.

  17. Molecular Events for Promotion of Vancomycin Resistance in Vancomycin Intermediate Staphylococcus aureus

    PubMed Central

    Hu, Qiwen; Peng, Huagang; Rao, Xiancai

    2016-01-01

    Vancomycin has been used as the last resort in the clinical treatment of serious Staphylococcus aureus infections. Vancomycin-intermediate S. aureus (VISA) was discovered almost two decades ago. Aside from the vancomycin-intermediate phenotype, VISA strains from the clinic or laboratory exhibited common characteristics, such as thickened cell walls, reduced autolysis, and attenuated virulence. However, the genetic mechanisms responsible for the reduced vancomycin susceptibility in VISA are varied. The comparative genomics of vancomycin-susceptible S. aureus (VSSA)/VISA pairs showed diverse genetic mutations in VISA; only a small number of these mutations have been experimentally verified. To connect the diversified genotypes and common phenotypes in VISA, we reviewed the genetic alterations in the relative determinants, including mutations in the vraTSR, graSR, walKR, stk1/stp1, rpoB, clpP, and cmk genes. Especially, we analyzed the mechanism through which diverse mutations mediate vancomycin resistance. We propose a unified model that integrates diverse gene functions and complex biochemical processes in VISA upon the action of vancomycin. PMID:27790199

  18. Unintended Consequences of US Immigration Policy: Explaining the Post-1965 Surge from Latin America

    PubMed Central

    Massey, Douglas S; Pren, Karen A.

    2012-01-01

    The year 1965 is often cited as a turning point in the history of US immigration, but what happened in the ensuing years is not well understood. Amendments to the Immigration and Nationality Act passed in that year repealed the national origins quotas, which had been enacted during the 1920s in a deliberate attempt to limit the entry of Southern and Eastern European immigrants—or more specifically Jews from the Russian Pale and Catholics from Poland and Italy, groups at the time deemed “unassimilable.” The quotas supplemented prohibitions already in place that effectively banned the entry of Asians and Africans. The 1965 amendments were intended to purge immigration law of its racist legacy by replacing the old quotas with a new system that allocated residence visas according to a neutral preference system based on family reunification and labor force needs. The new system is widely credited with having sparked a shift in the composition of immigration away from Europe toward Asia and Latin America, along with a substantial increase in the number of immigrants. PMID:22833862

  19. 22 CFR 51.20 - General.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS Application § 51.20 General. (a) An application for a passport, a replacement passport, extra visa pages, or other passport related service must be completed using the forms the Department prescribes. (b) The passport applicant must truthfully answer all...

  20. 22 CFR 51.20 - General.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS Application § 51.20 General. (a) An application for a passport, a replacement passport, extra visa pages, or other passport related service must be completed using the forms the Department prescribes. (b) The passport applicant must truthfully answer all...

  1. 22 CFR 51.20 - General.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS Application § 51.20 General. (a) An application for a passport, a replacement passport, extra visa pages, or other passport related service must be completed using the forms the Department prescribes. (b) The passport applicant must truthfully answer all...

  2. 22 CFR 51.20 - General.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS Application § 51.20 General. (a) An application for a passport, a replacement passport, extra visa pages, or other passport related service must be completed using the forms the Department prescribes. (b) The passport applicant must truthfully answer all...

  3. 22 CFR 51.20 - General.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS Application § 51.20 General. (a) An application for a passport, a replacement passport, extra visa pages, or other passport related service must be completed using the forms the Department prescribes. (b) The passport applicant must truthfully answer all...

  4. 77 FR 28922 - 30-Day Notice of Proposed Information Collection: DS-261, Electronic Choice of Address and Agent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    .... Originating Office: CA/VO/L/R. Form Number: DS-261. Respondents: Immigrant beneficiaries requesting change of... allows the beneficiary of an approved immigrant visa petition to provide the Department with his current...

  5. 22 CFR 41.33 - Nonresident alien Canadian border crossing identification card (BCC).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... identification card (BCC). 41.33 Section 41.33 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION... BCC or the BCC portion of a Canadian B-1/B-2 Visa/BCC issued to a permanent resident of Canada... officer may revoke a BCC or a B-1/B-2 Visa/BCC issued in Canada at any time under the provisions of § 41...

  6. Clinical and Microbiological Characteristics of Heteroresistant and Vancomycin-Intermediate Staphylococcus aureus from Bloodstream Infections in a Brazilian Teaching Hospital

    PubMed Central

    da Costa, Thaina Miranda; Morgado, Priscylla Guimarães Migueres; Cavalcante, Fernanda Sampaio; Damasco, Andreia Paredes; Nouér, Simone Aranha; dos Santos, Kátia Regina Netto

    2016-01-01

    This study analyzed clinical and microbiological characteristics of heteroresistant (hVISA) and vancomycin-intermediate Staphylococcus aureus (VISA) from bloodstream infections (BSI) in a Brazilian teaching hospital, between 2011 and 2013. Minimum inhibitory concentrations (MIC) of antimicrobials were determined by broth microdilution method and SCCmec was detected by PCR. Isolates with a vancomycin MIC ≥ 2mg/L were cultured on BHI agar with 3, 4 or 6 mg/L (BHIa3, BHIa4 or BHIa6) of vancomycin and BHIa4 with casein (BHIa4ca). Macromethod Etest® and Etest® Glicopeptides Resistance Detection were also used. VISA and hVISA isolates were confirmed by the population analysis profile then typed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing. Medical data from the patients were obtained from their medical records. Among 110 consecutive isolates, 31 (28%) were MRSA and carried the SCCmec type II (15 isolates) or IV (16 isolates). Vancomycin MIC50 and MIC90 were 1 and 2 mg/L, respectively. MRSA isolates had increased non-susceptibility to daptomycin (p = 0.0003). Six (5%) isolates were VISA, four of which were MRSA, three SCCmec type II/USA100/ST5 and one type IV/USA800/ST3192. One MRSA SCCmec II isolate grew on agar BHIa3, BHIa4 and BHIa4ca, and it was confirmed as hVISA. Among the six VISA isolates, five (83%) grew on BHIa3 and three (50%) on BHI4ca. Four of the six VISA isolates and the one hVISA isolate were from patients who had undergone dialysis. Thus, a possible dissemination of the SCCmec II/USA100/ST5 lineage may have occurred in the hospital comprising the VISA, hVISA and daptomycin non-susceptible S. aureus Brazilian isolates from health care associated bloodstream infections. PMID:27575698

  7. Clinical and Microbiological Characteristics of Heteroresistant and Vancomycin-Intermediate Staphylococcus aureus from Bloodstream Infections in a Brazilian Teaching Hospital.

    PubMed

    da Costa, Thaina Miranda; Morgado, Priscylla Guimarães Migueres; Cavalcante, Fernanda Sampaio; Damasco, Andreia Paredes; Nouér, Simone Aranha; Dos Santos, Kátia Regina Netto

    2016-01-01

    This study analyzed clinical and microbiological characteristics of heteroresistant (hVISA) and vancomycin-intermediate Staphylococcus aureus (VISA) from bloodstream infections (BSI) in a Brazilian teaching hospital, between 2011 and 2013. Minimum inhibitory concentrations (MIC) of antimicrobials were determined by broth microdilution method and SCCmec was detected by PCR. Isolates with a vancomycin MIC ≥ 2mg/L were cultured on BHI agar with 3, 4 or 6 mg/L (BHIa3, BHIa4 or BHIa6) of vancomycin and BHIa4 with casein (BHIa4ca). Macromethod Etest® and Etest® Glicopeptides Resistance Detection were also used. VISA and hVISA isolates were confirmed by the population analysis profile then typed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing. Medical data from the patients were obtained from their medical records. Among 110 consecutive isolates, 31 (28%) were MRSA and carried the SCCmec type II (15 isolates) or IV (16 isolates). Vancomycin MIC50 and MIC90 were 1 and 2 mg/L, respectively. MRSA isolates had increased non-susceptibility to daptomycin (p = 0.0003). Six (5%) isolates were VISA, four of which were MRSA, three SCCmec type II/USA100/ST5 and one type IV/USA800/ST3192. One MRSA SCCmec II isolate grew on agar BHIa3, BHIa4 and BHIa4ca, and it was confirmed as hVISA. Among the six VISA isolates, five (83%) grew on BHIa3 and three (50%) on BHI4ca. Four of the six VISA isolates and the one hVISA isolate were from patients who had undergone dialysis. Thus, a possible dissemination of the SCCmec II/USA100/ST5 lineage may have occurred in the hospital comprising the VISA, hVISA and daptomycin non-susceptible S. aureus Brazilian isolates from health care associated bloodstream infections.

  8. Relationship between day 1 and day 2 Vancomycin area under the curve values and emergence of heterogeneous Vancomycin-intermediate Staphylococcus aureus (hVISA) by Etest® macromethod among patients with MRSA bloodstream infections: a pilot study.

    PubMed

    Martirosov, Dmitriy M; Bidell, Monique R; Pai, Manjunath P; Scheetz, Marc H; Rosenkranz, Susan L; Faragon, Corey; Malik, M; Mendes, R E; Jones, R N; McNutt, Louise-Anne; Lodise, Thomas P

    2017-08-02

    In vitro data suggests that suboptimal initial vancomycin exposure may select for heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) infections. However, no clinical studies have evaluated the relationship between initial vancomycin exposure and emergence of hVISA. This pilot study seeks to assess the relationship between day 1 and day 2 vancomycin area under the curve (AUC) and emergence of hVISA bloodstream infections (BSIs) by Etest® macromethod among patients with a non-hVISA BSI at baseline. This was a retrospective cohort study of patients with methicillin-resistant Staphylococcus aureus (MRSA) BSIs at Albany Medical Center Hospital (AMCH) between January 2005 and June 2009. The vancomycin AUC exposure variables on day 1 (AUC 0-24h ) and day 2 (AUC 24-48h ) were estimated using the maximal a posteriori probability (MAP) procedure in ADAPT 5. There were 238 unique episodes of MRSA BSIs during the study period, 119 of which met inclusion criteria. Overall, hVISA emerged in 7/119 (5.9%) of patients. All 7 cases of hVISA involved patients who did not achieve area under the curve over broth microdilution minimum inhibitory concentration (AUC 0-24h /MIC BMD ) ratio of 521 or an AUC 24-48h /MIC BMD ratio of 650. No associations between other day 1 and day 2 AUC variables and emergence of hVISA were noted. Although more data are needed to draw definitive conclusions, these findings suggest that hVISA emergence among patients with non-hVISA MRSA BSIs at baseline may be partially explained by suboptimal exposure to vancomycin in the first 1 to 2 days of therapy. At a minimum, these findings support further study of the relationship between initial vancomycin exposure and hVISA emergence among patients with MRSA BSIs in a well-powered, multi-center, prospective trial.

  9. Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Nsp4 Cleaves VISA to Impair Antiviral Responses Mediated by RIG-I-like Receptors.

    PubMed

    Huang, Chen; Du, Yinping; Yu, Zhibin; Zhang, Qiong; Liu, Yihao; Tang, Jun; Shi, Jishu; Feng, Wen-Hai

    2016-06-22

    Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most significant etiological agents in the swine industry worldwide. It has been reported that PRRSV infection can modulate host immune responses, and innate immune evasion is thought to play a vital role in PRRSV pathogenesis. In this study, we demonstrated that highly pathogenic PRRSV (HP-PRRSV) infection specifically down-regulated virus-induced signaling adaptor (VISA), a unique adaptor molecule that is essential for retinoic acid induced gene-I (RIG-I) and melanoma differentiation associated gene 5 (MDA5) signal transduction. Moreover, we verified that nsp4 inhibited IRF3 activation induced by signaling molecules, including RIG-I, MDA5, VISA, and TBK1, but not IRF3. Subsequently, we demonstrated that HP-PRRSV nsp4 down-regulated VISA and suppressed type I IFN induction. Importantly, VISA was cleaved by nsp4 and released from mitochondrial membrane, which interrupted the downstream signaling of VISA. However, catalytically inactive mutant of nsp4 abolished its ability to cleave VISA. Interestingly, nsp4 of typical PRRSV strain CH-1a had no effect on VISA. Taken together, these findings reveal a strategy evolved by HP-PRRSV to counteract anti-viral innate immune signaling, which complements the known PRRSV-mediated immune-evasion mechanisms.

  10. [Visa at a tertiary hospital].

    PubMed

    Martínez-Jiménez, S; Lluch-Colomer, A; Desongles-Corrales, T; Bernal-González, D; Santos-Rubio, M D; Alfaro-Lara, E R; Galván-Banqueri, M

    2013-01-01

    To analyze the visa application process and his activity at a tertiary hosipital. Descriptive study of the drug s visa activity during the period April 2011-April 2012. We designed a database and defined categories on the study variables: patients and recipes. For patients admitted to the Visa Unit, issues detected were recorded based on a previously established classification. 6738 patients were included. They involved the visa of 8,465 recipes. The visa was applied to 170 drugs and nutrition products different, being the majority Tacrolimus. During this period, we detected a total of 420 incidents being the most frequent «No clinical document» (46.67%) and the «Formal completion errors» (28.57%). This work has allowed a more detailed analysis of the activity, the types of incidents and the identification of areas for improvement. Copyright © 2013 SEFH. Published by AULA MEDICA. All rights reserved.

  11. Genomic, Transcriptomic and Metabolomic Studies of Two Well-Characterized, Laboratory-Derived Vancomycin-Intermediate Staphylococcus aureus Strains Derived from the Same Parent Strain

    PubMed Central

    Hattangady, Dipti S.; Singh, Atul K.; Muthaiyan, Arun; Jayaswal, Radheshyam K.; Gustafson, John E.; Ulanov, Alexander V.; Li, Zhong; Wilkinson, Brian J.; Pfeltz, Richard F.

    2015-01-01

    Complete genome comparisons, transcriptomic and metabolomic studies were performed on two laboratory-selected, well-characterized vancomycin-intermediate Staphylococcus aureus (VISA) derived from the same parent MRSA that have changes in cell wall composition and decreased autolysis. A variety of mutations were found in the VISA, with more in strain 13136p−m+V20 (vancomycin MIC = 16 µg/mL) than strain 13136p−m+V5 (MIC = 8 µg/mL). Most of the mutations have not previously been associated with the VISA phenotype; some were associated with cell wall metabolism and many with stress responses, notably relating to DNA damage. The genomes and transcriptomes of the two VISA support the importance of gene expression regulation to the VISA phenotype. Similarities in overall transcriptomic and metabolomic data indicated that the VISA physiologic state includes elements of the stringent response, such as downregulation of protein and nucleotide synthesis, the pentose phosphate pathway and nutrient transport systems. Gene expression for secreted virulence determinants was generally downregulated, but was more variable for surface-associated virulence determinants, although capsule formation was clearly inhibited. The importance of activated stress response elements could be seen across all three analyses, as in the accumulation of osmoprotectant metabolites such as proline and glutamate. Concentrations of potential cell wall precursor amino acids and glucosamine were increased in the VISA strains. Polyamines were decreased in the VISA, which may facilitate the accrual of mutations. Overall, the studies confirm the wide variability in mutations and gene expression patterns that can lead to the VISA phenotype. PMID:27025616

  12. VISA is required for B cell expression of TLR7.

    PubMed

    Xu, Liang-Guo; Jin, Lei; Zhang, Bi-Cheng; Akerlund, Linda J; Shu, Hong-Bing; Cambier, John C

    2012-01-01

    B cells play a critical role in the initialization and development of the systemic lupus erythematosus that is dependent on the expression of the endosomal ssRNA receptor TLR7. Previous studies have established that B cell expression of TLR7 is controlled by the type I IFN secreted by plasmacytoid dendritic cells. In this article, we report that VISA, also known as MAVS, IPS-1, and CardIf, essential for RIG-I/MDA5-mediated signaling following sensing of cytosolic RNA, regulate B cell expression of TLR7 and CD23. We found that B cells from a VISA(-/-) mouse express reduced TLR7 but normal basal levels of type I IFN. We also show that although IFN-β and TLR7 agonists synergize to promote TLR7 expression in VISA(-/-) B cells, they do not fully complement the defect seen in VISA(-/-) cells. Cell transfer experiments revealed that the observed effects of VISA(-/-) are B cell intrinsic. The reduced TLR7 expression in B cells is correlated with impaired TLR7 agonist-induced upregulation of activation markers CD69 and CD86, cell proliferation, production of IFN-α, TNF, and IL-12, and NF-κB activation. Finally, studies indicate that genetic background may influence the observed phenotype of our VISA(-/-) mice, because VISA(-/-) B cells differ in CD23 and TLR7 expression when on C57BL/6 versus 129Sv-C57BL/6 background. Thus, our findings suggest an unexpected link between VISA-mediated cytosolic RLR signaling and autoimmunity.

  13. Delayed Workforce Entry and High Emigration Rates for Recent Canadian Radiation Oncology Graduates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Loewen, Shaun K., E-mail: shaun.loewen@cancercare.mb.ca; Halperin, Ross; Lefresne, Shilo

    Purpose: To determine the employment status and location of recent Canadian radiation oncology (RO) graduates and to identify current workforce entry trends. Methods and Materials: A fill-in-the-blank spreadsheet was distributed to all RO program directors in December 2013 and June 2014, requesting the employment status and location of their graduates over the last 3 years. Visa trainee graduates were excluded. Results: Response rate from program directors was 100% for both survey administrations. Of 101 graduates identified, 99 (98%) had known employment status and location. In the December survey, 5 2013 graduates (16%), 17 2012 graduates (59%), and 18 2011 graduates (75%) hadmore » permanent staff employment. Six months later, 5 2014 graduates (29%), 15 2013 graduates (48%), 24 2012 graduates (83%), and 21 2011 graduates (88%) had secured staff positions. Fellowships and temporary locums were common for those without staff employment. The proportion of graduates with staff positions abroad increased from 22% to 26% 6 months later. Conclusions: Workforce entry for most RO graduates was delayed but showed steady improvement with longer time after graduation. High emigration rates for jobs abroad signify domestic employment challenges for newly certified, Canadian-trained radiation oncologists. Coordination on a national level is required to address and regulate radiation oncologist supply and demand disequilibrium in Canada.« less

  14. 78 FR 35044 - U.S. Customs and Border Protection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Visa Waiver Program Carrier Agreement (CBP Form I-775) AGENCY: U.S. Customs and Border Protection... information collection: 1651-0110. SUMMARY: U.S. Customs and Border Protection (CBP) of the Department of...

  15. Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Nsp4 Cleaves VISA to Impair Antiviral Responses Mediated by RIG-I-like Receptors

    PubMed Central

    Huang, Chen; Du, Yinping; Yu, Zhibin; Zhang, Qiong; Liu, Yihao; Tang, Jun; Shi, Jishu; Feng, Wen-hai

    2016-01-01

    Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most significant etiological agents in the swine industry worldwide. It has been reported that PRRSV infection can modulate host immune responses, and innate immune evasion is thought to play a vital role in PRRSV pathogenesis. In this study, we demonstrated that highly pathogenic PRRSV (HP-PRRSV) infection specifically down-regulated virus-induced signaling adaptor (VISA), a unique adaptor molecule that is essential for retinoic acid induced gene-I (RIG-I) and melanoma differentiation associated gene 5 (MDA5) signal transduction. Moreover, we verified that nsp4 inhibited IRF3 activation induced by signaling molecules, including RIG-I, MDA5, VISA, and TBK1, but not IRF3. Subsequently, we demonstrated that HP-PRRSV nsp4 down-regulated VISA and suppressed type I IFN induction. Importantly, VISA was cleaved by nsp4 and released from mitochondrial membrane, which interrupted the downstream signaling of VISA. However, catalytically inactive mutant of nsp4 abolished its ability to cleave VISA. Interestingly, nsp4 of typical PRRSV strain CH-1a had no effect on VISA. Taken together, these findings reveal a strategy evolved by HP-PRRSV to counteract anti-viral innate immune signaling, which complements the known PRRSV-mediated immune-evasion mechanisms. PMID:27329948

  16. Mutation of RNA polymerase beta subunit (rpoB) promotes hVISA-to-VISA phenotypic conversion of strain Mu3.

    PubMed

    Matsuo, Miki; Hishinuma, Tomomi; Katayama, Yuki; Cui, Longzhu; Kapi, Maria; Hiramatsu, Keiichi

    2011-09-01

    The clinical vancomycin-intermediate Staphylococcus aureus (VISA) strain Mu50 carries two mutations in the vraSR and graRS two-component regulatory systems (TCRSs), namely, vraS(I5N) and graR(N197S) (hereinafter designated graR). The clinical heterogeneously vancomycin-intermediate S. aureus (hVISA) strain Mu3 shares with Mu50 the mutation in vraS that encodes the VraS two-component histidine kinase. Previously, we showed that introduction of the plasmid pgraR, carrying the mutated two-component response regulator graR, converted the hVISA strain Mu3 into VISA (vancomycin MIC = 4 mg/liter). Subsequently, however, we found that the introduction of a single copy of graR into the Mu3 chromosome by a gene replacement method did not confer on Mu3 the VISA phenotype. The gene-replaced strain Mu3graR thus obtained remained hVISA (MIC ≤ 2 mg/liter), although a small increase in vancomycin MIC was observed compared to that of the parent strain Mu3. Reevaluation of the Mu3 and Mu50 genomes revealed the presence of another mutation responsible for the expression of the VISA phenotype in Mu50. Here, we demonstrate that in addition to the two regulator mutations, a third mutation found in the Mu50 rpoB gene, encoding the RNA polymerase β subunit, was required for Mu3 to achieve the level of vancomycin resistance of Mu50. The selection of strain Mu3graR with rifampin gave rise to rpoB mutants with various levels of increased vancomycin resistance. Furthermore, 3 (33%) of 10 independently isolated VISA strains established from the heterogeneous subpopulations of Mu3graR were found to possess rpoB mutations with or without an accompanying rifampin-resistance phenotype. The data indicate that a sizable proportion of the resistant hVISA cell subpopulations is composed of spontaneous rpoB mutants with various degrees of increased vancomycin resistance.

  17. 22 CFR 41.42 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false [Reserved] 41.42 Section 41.42 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Crewman and Crew-List Visas § 41.42 [Reserved] ...

  18. 22 CFR 41.42 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false [Reserved] 41.42 Section 41.42 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Crewman and Crew-List Visas § 41.42 [Reserved] ...

  19. 22 CFR 41.42 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false [Reserved] 41.42 Section 41.42 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Crewman and Crew-List Visas § 41.42 [Reserved] ...

  20. 22 CFR 41.42 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false [Reserved] 41.42 Section 41.42 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Crewman and Crew-List Visas § 41.42 [Reserved] ...

  1. 22 CFR 41.42 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false [Reserved] 41.42 Section 41.42 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Crewman and Crew-List Visas § 41.42 [Reserved] ...

  2. Targeted expression of BikDD combined with metronomic doxorubicin induces synergistic antitumor effect through Bax activation in hepatocellular carcinoma

    PubMed Central

    Dai, Huei-Yue; Chen, Hui-Yu; Lai, Wei-Chen; Hung, Mien-Chie; Li, Long-Yuan

    2015-01-01

    Conventional chemotherapy is commonly used to treat advanced non-resectable hepatocellular carcinoma (HCC) but this treatment modality has not demonstrated convincing survival benefit in HCC patients. Our previous studies indicated that targeted expression of therapeutic BikDD driven by a liver cancer-specific α-fetoprotein promoter/enhancer (eAFP) in the VISA backbone (eAFP-VISA-BikDD) significantly and specifically kills HCC cells in multiple orthotopic animal models. To enhance its therapeutic efficacy, we combined eAFP-VISA-BikDD with chemotherapeutic agents and found that eAFP-VISA-BikDD plus doxorubicin (Dox) or 5-fluorouracil (5-FU) demonstrated synergistic cytotoxicity in HCC cells. Specifically, the combination of eAFP-VISA-BikDD plus Dox markedly induced apoptosis via increased Bax mitochondrial translocation and cytoplasmic cytochrome c release. Compared with either agent alone, a low dose of Dox combined with eAFP-VISA-BikDD induced better antitumor effect and prolonged longer survival of mice in two orthotopic liver cancer xenograft models. Our findings provide strong preclinical support for evaluating the combined therapy of eAFP-VISA-BikDD and Dox in a clinical setting as a treatment option for HCC. PMID:26247632

  3. 22 CFR 41.106 - Processing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Processing. 41.106 Section 41.106 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.106 Processing. Consular officers must...

  4. 22 CFR 41.106 - Processing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Processing. 41.106 Section 41.106 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.106 Processing. Consular officers must...

  5. 22 CFR 41.106 - Processing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Processing. 41.106 Section 41.106 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.106 Processing. Consular officers must...

  6. 22 CFR 41.106 - Processing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Processing. 41.106 Section 41.106 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.106 Processing. Consular officers must...

  7. 22 CFR 41.106 - Processing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Processing. 41.106 Section 41.106 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.106 Processing. Consular officers must...

  8. Visual Impairment Screening Assessment (VISA) tool: pilot validation.

    PubMed

    Rowe, Fiona J; Hepworth, Lauren R; Hanna, Kerry L; Howard, Claire

    2018-03-06

    To report and evaluate a new Vision Impairment Screening Assessment (VISA) tool intended for use by the stroke team to improve identification of visual impairment in stroke survivors. Prospective case cohort comparative study. Stroke units at two secondary care hospitals and one tertiary centre. 116 stroke survivors were screened, 62 by naïve and 54 by non-naïve screeners. Both the VISA screening tool and the comprehensive specialist vision assessment measured case history, visual acuity, eye alignment, eye movements, visual field and visual inattention. Full completion of VISA tool and specialist vision assessment was achieved for 89 stroke survivors. Missing data for one or more sections typically related to patient's inability to complete the assessment. Sensitivity and specificity of the VISA screening tool were 90.24% and 85.29%, respectively; the positive and negative predictive values were 93.67% and 78.36%, respectively. Overall agreement was significant; k=0.736. Lowest agreement was found for screening of eye movement and visual inattention deficits. This early validation of the VISA screening tool shows promise in improving detection accuracy for clinicians involved in stroke care who are not specialists in vision problems and lack formal eye training, with potential to lead to more prompt referral with fewer false positives and negatives. Pilot validation indicates acceptability of the VISA tool for screening of visual impairment in stroke survivors. Sensitivity and specificity were high indicating the potential accuracy of the VISA tool for screening purposes. Results of this study have guided the revision of the VISA screening tool ahead of full clinical validation. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  9. Faculty Member's Guide to U.S. Immigration Law. Revised.

    ERIC Educational Resources Information Center

    Smith, Eugene H.; Baron, Marvin J.

    Immigration laws and regulations pertaining to foreign students and scholars are summarized as an aid to faculty members. Basic immigration documents and terminology are explained, including the passport, visa, immigration status or classification, Form 1-20 ID, the "green card", and Departure Record. Classes of nonimmigrants are described,…

  10. U.S. Visa Waiver Program Changes

    NASA Astrophysics Data System (ADS)

    The U.S. State Department has just announced that a change to a new rule affecting citizens from visa waiver program countries. The rule, scheduled to go into effect on 1 October 2003, requires visitors from these countries to obtain non-immigrant visas to enter the United States if they do not have machine-readable passports. The change announced is that a visa waiver country can petition the U.S. government to delay the rule by one year. The State Department recommends that citizens of visa waiver program countries who are contemplating visiting the United States, and do not have machine-readable passports, contact the nearest U.S. embassy or consulate to find out if implementation of the rule has been temporarily waived for their countries.

  11. 22 CFR 41.0 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Definitions. 41.0 Section 41.0 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Passport and Visas Not Required for Certain Nonimmigrants § 41.0 Definitions. For...

  12. 22 CFR 41.0 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Definitions. 41.0 Section 41.0 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Passport and Visas Not Required for Certain Nonimmigrants § 41.0 Definitions. For...

  13. 22 CFR 41.0 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Definitions. 41.0 Section 41.0 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Passport and Visas Not Required for Certain Nonimmigrants § 41.0 Definitions. For...

  14. 22 CFR 41.0 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Definitions. 41.0 Section 41.0 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Passport and Visas Not Required for Certain Nonimmigrants § 41.0 Definitions. For...

  15. 22 CFR 41.0 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Definitions. 41.0 Section 41.0 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Passport and Visas Not Required for Certain Nonimmigrants § 41.0 Definitions. For...

  16. 8 CFR 217.2 - Eligibility.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS VISA WAIVER PROGRAM § 217.2 Eligibility... must present a machine-readable passport in order to be granted admission under the Visa Waiver Program. Round trip ticket means any return trip transportation ticket in the name of an arriving Visa Waiver...

  17. Go8 Note: Student Visas

    ERIC Educational Resources Information Center

    Group of Eight (NJ1), 2012

    2012-01-01

    An independent review of the Australian student visa program was completed in 2011. Several of the recommendations from the review have been implemented by the Australian government, including the introduction of streamlined visa processing for applicants enrolled at an Australian university and increased flexibility in working conditions for…

  18. ECSIT bridges RIG-I-like receptors to VISA in signaling events of innate antiviral responses.

    PubMed

    Lei, Cao-Qi; Zhang, Yu; Li, Mi; Jiang, Li-Qun; Zhong, Bo; Kim, Yong Ho; Shu, Hong-Bing

    2015-01-01

    Upon binding to RNA structures from invading viruses, RIG-I and MDA5 are recruited to mitochondria to interact with VISA and initiate antiviral type I interferon (IFN) responses. How this process is mediated is less understood. In this report, we demonstrate that ECSIT is an essential scaffolding protein that mediates the association of VISA and RIG-I or MDA5. Overexpression of ECSIT potentiated virus-triggered activation of IFN-regulatory factor 3 (IRF3) and expression of IFNB1, whereas knockdown of ECSIT impaired viral infection-induced activation of IRF3 and expression of IFNB1 as well as cellular antiviral responses. Mechanistically, ECSIT was associated with VISA on mitochondria and important for bridging RIG-I and MDA5 to VISA. Our findings suggest that ECSIT mediates virus-triggered type I IFN induction by bridging RIG-I and MDA5 to the VISA complex, and provide new insights into the molecular events of innate antiviral immune responses. © 2014 S. Karger AG, Basel.

  19. Reliability and Validity of the Korean Version VISA-P Questionnaire for Patellar Tendinopathy in Adolescent Elite Volleyball Athletes.

    PubMed

    Park, Byung-Hyun; Seo, Jeong-Hwan; Ko, Myoung-Hwan; Park, Sung-Hee

    2013-10-01

    To translate the English Victorian Institute of Sport Assessment for patellar tendinopathy (VISA-P) questionnaire into a Korean version and to determine the reliability and validity of the Korean version. The English VISA-P questionnaire was translated into Korean according to the internationally recommended guidelines. Then, 28 adolescent elite volleyball athletes (average age, 16 years; range, 14 to 19 years) were asked to complete the questionnaire three times (before examination, after examination, and 1 week later) for reliability. They were evaluated through a physical examination and ultrasonography to diagnosis patellar tendinopathy. The internal consistency of the VISA-P questionnaire by Cronbach's alpha was 0.80 for the first, 0.78 for the second, and 0.79 for the third assessment. The intraclass correlation coefficient (ICC) between the first and second assessments was 0.97. The ICC between the second and third assessments was 0.96. The mean VISA-P scores were 67.6±15.7 for the patellar tendinopathy group (n=23) and 92.6±8.6 for the normal group (n=5). There were significantly lower VISA-P scores in the patellar tendinopathy group compared to the normal group. The translated Korean version VISA-P questionnaire has good internal consistency, test-retest reliability and validity. In addition, this study indicated that most adolescent elite volleyball athletes had patellar tendon problems. Therefore, the Korean version VISA-P is a useful self-administered outcome score of athletes with patellar tendinopathy.

  20. Danish VISA-A questionnaire with validation and reliability testing for Danish-speaking Achilles tendinopathy patients.

    PubMed

    Iversen, J V; Bartels, E M; Jørgensen, J E; Nielsen, T G; Ginnerup, C; Lind, M C; Langberg, H

    2016-12-01

    The VISA-A questionnaire has proven to be a valid and reliable tool for assessing severity of Achilles tendinopathy (AT). The aim was to translate and cross-culturally adapt the VISA-A questionnaire for a Danish-speaking AT population, and subsequently perform validity and reliability tests. Translation and following cross-cultural adaptation was performed as translation, synthesis, reverse translation, expert review, and pretesting. The final Danish version (VISA-A-DK) was tested for reliability on healthy controls (n = 75) and patients (n = 36). Tests for internal consistency, validity, and structure were performed on 71 patients. VISA-A-DK showed good reliability for patients (r = 0.80 ICC = 0.79) and healthy individuals (r = 0.98 ICC = 0.97). Internal consistency was 0.73 (Cronbach's alpha). The mean VISA-A-DK score in AT patients was 51 [47-55]. This was significantly lower than healthy controls with a score of 93 (90-95). Criterion validity was considered good when comparing the scores of the Danish version with the original version in both healthy individuals and patients. VISA-A-DK is a valid and reliable instrument and has shown compatible to the original version in assessment of AT patients. VISA-A-DK is a useful tool in the assessment of AT, both in research and in a clinical setting. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. 22 CFR 41.54 - Intracompany transferees (executives, managers, and specialized knowledge employees).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., and specialized knowledge employees). 41.54 Section 41.54 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.54 Intracompany transferees (executives, managers, and specialized knowledge employees...

  2. 22 CFR 41.54 - Intracompany transferees (executives, managers, and specialized knowledge employees).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., and specialized knowledge employees). 41.54 Section 41.54 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.54 Intracompany transferees (executives, managers, and specialized knowledge employees...

  3. 22 CFR 41.54 - Intracompany transferees (executives, managers, and specialized knowledge employees).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., and specialized knowledge employees). 41.54 Section 41.54 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.54 Intracompany transferees (executives, managers, and specialized knowledge employees...

  4. 19 CFR 143.23 - Form of entry.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (CONTINUED) SPECIAL ENTRY PROCEDURES Informal Entry § 143.23 Form of entry. Except for the types of... upper right hand corner. (g) Merchandise, regardless of value, which is imported for noncommercial... credit, Customs Form 7501, annotated “informal entry” in the upper right hand corner, and Customs Form...

  5. 78 FR 66813 - Visas: Regulatory Exception to Permit Compliance With the United Nations Headquarters Agreement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ... Visa Classifications; Final Rule #0;#0;Federal Register / Vol. 78, No. 215 / Wednesday, November 6... Family'' for Certain Nonimmigrant Visa Classifications AGENCY: Department of State. ACTION: Final rule... classifications and also applies to foreign government officials who may be admitted in immediate and continuous...

  6. 78 FR 22937 - 60-Day Notice of Proposed Information Collection: Application for Additional Visa Pages or...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-17

    ...: Application for Additional Visa Pages or Miscellaneous Passport Services ACTION: Notice of request for public... Information Collection: Application for Additional Visa Pages or Miscellaneous Passport Services. OMB Control...: Bureau of Consular Affairs, Passport Services, Office of Program Management and Operational Support...

  7. 22 CFR 40.1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH NONIMMIGRANTS AND IMMIGRANTS UNDER THE... immigrant visa within 6 months of: (i) The date of issuance of a visa to the principal alien; (ii) The date... foreign state chargeability or immigrant status upon a spouse or child. (2) An “accompanying” relative may...

  8. 78 FR 31398 - Visas: Documentation of Immigrants Under the Immigration and Nationality Act, as Amended

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... Immigrants Under the Immigration and Nationality Act, as Amended AGENCY: Department of State. ACTION: Final... method of recording an alien's entitlement to an immigrant visa classification. Due to the availability of automated systems at all immigrant visa-issuing posts, this entitlement is now recorded...

  9. 22 CFR 42.21 - Immediate relatives.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Immigrants Not Subject to Numerical Limitations of INA 201 and 202 § 42.21... of Alien Relative for Issuance of an Immigrant Visa, filed on the alien's behalf by the U.S. citizen...

  10. 22 CFR 42.41 - Effect of approved petition.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Effect of approved petition. 42.41 Section 42.41 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... officer that the alien is eligible in all respects to receive a visa. [56 FR 49682, Oct. 1, 1991] ...

  11. 22 CFR 42.41 - Effect of approved petition.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Effect of approved petition. 42.41 Section 42.41 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... officer that the alien is eligible in all respects to receive a visa. [56 FR 49682, Oct. 1, 1991] ...

  12. 22 CFR 41.41 - Crewmen.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Crewmen. 41.41 Section 41.41 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Crewman and Crew-List Visas § 41.41 Crewmen. (a) Alien classifiable as crewman. An alien is...

  13. 22 CFR 41.41 - Crewmen.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Crewmen. 41.41 Section 41.41 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Crewman and Crew-List Visas § 41.41 Crewmen. (a) Alien classifiable as crewman. An alien is...

  14. 22 CFR 42.41 - Effect of approved petition.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Effect of approved petition. 42.41 Section 42.41 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... officer that the alien is eligible in all respects to receive a visa. [56 FR 49682, Oct. 1, 1991] ...

  15. 22 CFR 42.54 - Order of consideration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Order of consideration. 42.54 Section 42.54 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND...(b) in order to apply formally for a visa as follows: (1) In the chronological order of the priority...

  16. 22 CFR 41.41 - Crewmen.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Crewmen. 41.41 Section 41.41 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Crewman and Crew-List Visas § 41.41 Crewmen. (a) Alien classifiable as crewman. An alien is...

  17. 8 CFR 217.4 - Inadmissibility and deportability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Section 217.4 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS VISA WAIVER... lack of a visa), or who is in possession of and presents fraudulent or counterfeit travel documents... immigration judge for a determination of deportability, except that an alien who was admitted as a Visa Waiver...

  18. 22 CFR 42.41 - Effect of approved petition.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Effect of approved petition. 42.41 Section 42.41 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE... officer that the alien is eligible in all respects to receive a visa. [56 FR 49682, Oct. 1, 1991] ...

  19. 22 CFR 42.54 - Order of consideration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Order of consideration. 42.54 Section 42.54 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF IMMIGRANTS UNDER THE IMMIGRATION AND...(b) in order to apply formally for a visa as follows: (1) In the chronological order of the priority...

  20. 22 CFR 41.41 - Crewmen.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Crewmen. 41.41 Section 41.41 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF NONIMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Crewman and Crew-List Visas § 41.41 Crewmen. (a) Alien classifiable as crewman. An alien is...

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