Sample records for w-320 241-c-106 sluicing

  1. Project W-320, 241-C-106 sluicing HVAC calculations, Volume 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bailey, J.W.

    1998-08-07

    This supporting document has been prepared to make the FDNW calculations for Project W-320, readily retrievable. The report contains the following calculations: Exhaust airflow sizing for Tank 241-C-106; Equipment sizing and selection recirculation fan; Sizing high efficiency mist eliminator; Sizing electric heating coil; Equipment sizing and selection of recirculation condenser; Chiller skid system sizing and selection; High efficiency metal filter shielding input and flushing frequency; and Exhaust skid stack sizing and fan sizing.

  2. Project W-320, 241-C-106 sluicing electrical calculations, Volume 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bailey, J.W.

    1998-08-07

    This supporting document has been prepared to make the FDNW calculations for Project W-320, readily retrievable. These calculations are required: To determine the power requirements needed to power electrical heat tracing segments contained within three manufactured insulated tubing assemblies; To verify thermal adequacy of tubing assembly selection by others; To size the heat tracing feeder and branch circuit conductors and conduits; To size protective circuit breaker and fuses; and To accomplish thermal design for two electrical heat tracing segments: One at C-106 tank riser 7 (CCTV) and one at the exhaust hatchway (condensate drain). Contents include: C-Farm electrical heat tracing;more » Cable ampacity, lighting, conduit fill and voltage drop; and Control circuit sizing and voltage drop analysis for the seismic shutdown system.« less

  3. W-320 Department of Health documentation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bailey, J.W.

    1998-08-07

    The purpose of this document is to gather information required to show that Project W-320 is in compliance with Washington State Department of Health requirements as specified in Radioactive Air Emissions Notice of Construction Project W-320, Tank 241-C-106 Sluicing, DOE/RL-95-45. Specifically, that W-320 is in compliance with ASME N509-1989 (Nuclear Power Plant Air-Cleaning Units and Components) and ASME N5 10-1989 (Testing of Nuclear Air Treatment Systems) for the 296-C-006 exhaust system.

  4. Project W-320, tank 241-C-106 sluicing acceptance for beneficial use

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    BAILEY, J.W.

    The purpose of this document is to identify the Project W-320 Chiller Documentation required to be turned over from the Projects Organization to Tank Farm Operations as part of the acceptance of the new equipment for beneficial use.

  5. Safety evaluation for packaging transportation of equipment for tank 241-C-106 waste sluicing system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Calmus, D.B.

    1994-08-25

    A Waste Sluicing System (WSS) is scheduled for installation in nd waste storage tank 241-C-106 (106-C). The WSS will transfer high rating sludge from single shell tank 106-C to double shell waste tank 241-AY-102 (102-AY). Prior to installation of the WSS, a heel pump and a transfer pump will be removed from tank 106-C and an agitator pump will be removed from tank 102-AY. Special flexible receivers will be used to contain the pumps during removal from the tanks. After equipment removal, the flexible receivers will be placed in separate containers (packagings). The packaging and contents (packages) will be transferredmore » from the Tank Farms to the Central Waste Complex (CWC) for interim storage and then to T Plant for evaluation and processing for final disposition. Two sizes of packagings will be provided for transferring the equipment from the Tank Farms to the interim storage facility. The packagings will be designated as the WSSP-1 and WSSP-2 packagings throughout the remainder of this Safety Evaluation for Packaging (SEP). The WSSP-1 packagings will transport the heel and transfer pumps from 106-C and the WSSP-2 packaging will transport the agitator pump from 102-AY. The WSSP-1 and WSSP-2 packagings are similar except for the length.« less

  6. Chemical and chemically-related considerations associated with sluicing tank C-106 waste to tank AY-102

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reynolds, D.A.

    1997-04-04

    New data on tank 241-C-106 were obtained from grab sampling and from compatibility testing of tank C-106 and tank AY-102 wastes. All chemistry-associated and other compatibility Information compiled in this report strongly suggests that the sluicing of the contents of tank C-106, in accord with appropriate controls, will pose no unacceptable risk to workers, public safety, or the environment. In addition, it is expected that the sluicing operation will successfully resolve the High-Heat Safety Issue for tank C-106.

  7. Waste retrieval sluicing system data acquisition system acceptance test report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bevins, R.R.

    1998-07-31

    This document describes the test procedure for the Project W-320 Tank C-106 Sluicing Data Acquisition System (W-320 DAS). The Software Test portion will test items identified in the WRSS DAS System Description (SD), HNF-2115. Traceability to HNF-2115 will be via a reference that follows in parenthesis, after the test section title. The Field Test portion will test sensor operability, analog to digital conversion, and alarm setpoints for field instrumentation. The W-320 DAS supplies data to assist thermal modeling of tanks 241-C-106 and 241-AY-102. It is designed to be a central repository for information from sources that would otherwise have tomore » be read, recorded, and integrated manually. Thus, completion of the DAS requires communication with several different data collection devices and output to a usable PC data formats. This test procedure will demonstrate that the DAS functions as required by the project requirements stated in Section 3 of the W-320 DAS System Description, HNF-2115.« less

  8. Operational test report -- Project W-320 cathodic protection systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bowman, T.J.

    1998-06-16

    Washington Administrative Code (WAC) 173-303-640 specifies that corrosion protection must be designed into tank systems that treat or store dangerous wastes. Project W-320, Waste Retrieval Sluicing System (WRSS), utilizes underground encased waste transfer piping between tanks 241-C-106 and 241-AY-102. Corrosion protection is afforded to the encasements of the WRSS waste transfer piping through the application of earthen ionic currents onto the surface of the piping encasements. Cathodic protection is used in conjunction with the protective coatings that are applied upon the WRSS encasement piping. WRSS installed two new two rectifier systems (46 and 47) and modified one rectifier system (31).more » WAC 173-303-640 specifies that the proper operation of cathodic protection systems must be confirmed within six months after initial installation. The WRSS cathodic protection systems were energized to begin continuous operation on 5/5/98. Sixteen days after the initial steady-state start-up of the WRSS rectifier systems, the operational testing was accomplished with procedure OTP-320-006 Rev/Mod A-0. This operational test report documents the OTP-320-006 results and documents the results of configuration testing of integrated piping and rectifier systems associated with the W-320 cathodic protection systems.« less

  9. Simulation of Hanford Tank 241-C-106 Waste Release into Tank 241-Y-102

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    KP Recknagle; Y Onishi

    Waste stored in Hdord single-shell Tank 241-C-106 will be sluiced with a supernatant liquid from doubIe-shell Tank 241 -AY- 102 (AY-1 02) at the U.S. Department of Energy's Har@ord Site in Eastern Washington. The resulting slurry, containing up to 30 wtYo solids, will then be transferred to Tank AY-102. During the sluicing process, it is important to know the mass of the solids being transferred into AY- 102. One of the primary instruments used to measure solids transfer is an E+ densitometer located near the periphery of the tank at riser 15S. This study was undert.dcen to assess how wellmore » a densitometer measurement could represent the total mass of soiids transferred if a uniform lateral distribution was assumed. The study evaluated the C-1 06 slurry mixing and accumulation in Tank AY- 102 for the following five cases: Case 1: 3 wt'%0 slurry in 6.4-m AY-102 waste Case 2: 3 w-t% slurry in 4.3-m AY-102 waste Case 3: 30 wtYo slurry in 6.4-m AY-102 waste Case 4: 30 wt% slurry in 4.3-m AY-102 waste Case 5: 30 wt% slurry in 5. O-m AY-102 waste. The tirne-dependent, three-dimensional, TEMPEST computer code was used to simulate solid deposition and accumulation during the injection of the C-106 slurry into AY-102 through four injection nozzles. The TEMPEST computer code was applied previously to other Hanford tanks, AP-102, SY-102, AZ-101, SY-101, AY-102, and C-106, to model tank waste mixing with rotating pump jets, gas rollover events, waste transfer from one tank to another, and pump-out retrieval of the sluiced waste. The model results indicate that the solid depth accumulated at the densitometer is within 5% of the average depth accumulation. Thus the reading of the densitometer is expected to represent the total mass of the transferred solids reasonably well.« less

  10. Repository of not readily available documents for project W-320

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Conner, J.C.

    1997-04-18

    The purpose of this document is to provide a readily available source of the technical reports needed for the development of the safety documentation provided for the waste retrieval sluicing system (WRSS), designed to remove the radioactive and chemical sludge from tank 241-C-106, and transport that material to double-shell tank 241-AY-102 via a new, temporary, shielded, encased transfer line.

  11. System design description for portable 1,000 CFM exhauster Skids POR-007/Skid E and POR-008/Skid F

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nelson, O.D.

    1998-07-25

    The primary purpose of the two 1,000 CFM Exhauster Skids, POR-007-SKID E and POR-008-SKID F, is to provide backup to the waste tank primary ventilation systems for tanks 241-C-106 and 241-AY-102, and the AY-102 annulus in the event of a failure during the sluicing of tank 241-C-106 and subsequent transfer of sluiced waste to 241-AY-102. This redundancy is required since both of the tank ventilation systems have been declared as Safety Class systems.

  12. Cone Penetrometer Shear Strength Measurements of Sludge Waste in Tanks 241-AN-101 and 241-AN-106

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Follett, Jordan R.

    2014-03-06

    This document presents the resulting shear strength profiles for sludge waste in Tanks 241-AN-101 and 241-AN-106, as determined with a full-flow cone penetrometer. Full-flow penetrometer measurements indicate shear strength profiles that increase roughly uniformly with depth. For Tank 241-AN-101, the undrained shear strength was calculated to range from 500 Pa near the sludge surface to roughly 3,300 Pa at 15 inches above the tank bottom. For 241-AN-106, the undrained shear strength was calculated to range from 500 Pa near the sludge surface to roughly 5,000 Pa at 15 inches above the tank bottom.

  13. Development of a Self-Sluicing Pressure Leaf Filter

    NASA Astrophysics Data System (ADS)

    Cousineau, Bernard L.; Lumsden, J. R.

    The cylindrical Kelly filter presses installed in the Ewarton Works "C" phase did not perform satisfactorily because of difficulties with head seals, locking rings, and shell retraction mechanisms. As rectification required major modifications, a concept of a press which did not require to be opened for sluicing was proposed. Test work of various sluicing and res lurrying spray arrangements was carried out, and this led to the design of a self-sluicing press which used the shell of an existing Kelly press with its main axis vertical. One press was converted by July 1972, and a development period started. Although initial operation was encouraging, effective sluicing could not be guaranteed after 30 shifts. Modifications to leaf spacing, spray rotational speed, spray slot width, feed pressure and pre-coat control by November 1973, however, allowed effective performance for all of the 800 hour canvas life. Advantages are: reduced operating and maintenance manpower, clean environment, and reduced maintenance cost. The use of 1st wash overflow for sluicing has reduced caustic soda and canvas consumption. Ewarton Works now has four converted self-sluicing presses, and arc converting five more, and Arvida Works plan the installation of one for tests on red pressing (blow-off filtration). A side benefit of the development was the study of the benefits of constant pressure overflow filtration.

  14. Residues W320 and Y328 within the binding site of the μ-opioid receptor influence opiate ligand bias.

    PubMed

    Hothersall, J Daniel; Torella, Rubben; Humphreys, Sian; Hooley, Monique; Brown, Alastair; McMurray, Gordon; Nickolls, Sarah A

    2017-05-15

    The development of G protein-biased agonists for the μ-opioid receptor (MOR) offers a clear drug discovery rationale for improved analgesia and reduced side-effects of opiate pharmacotherapy. However, our understanding of the molecular mechanisms governing ligand bias is limited, which hinders our ability to rationally design biased compounds. We have investigated the role of MOR binding site residues W320 and Y328 in controlling bias, by receptor mutagenesis. The pharmacology of a panel of ligands in a cAMP and a β-arrestin2 assay were compared between the wildtype and mutated receptors, with bias factors calculated by operational analysis using ΔΔlog(τ/K A ) values. [ 3 H]diprenorphine competition binding was used to estimate affinity changes. Introducing the mutations W320A and Y328F caused changes in pathway bias, with different patterns of change between ligands. For example, DAMGO increased relative β-arrestin2 activity at the W320A mutant, whilst its β-arrestin2 response was completely lost at Y328F. In contrast, endomorphin-1 gained activity with Y328F but lost activity at W320A, in both pathways. For endomorphin-2 there was a directional shift from cAMP bias at the wildtype towards more β-arrestin2 bias at W320A. We also observe clear uncoupling between mutation-driven changes in function and binding affinity. These findings suggest that the mutations influenced the balance of pathway activation in a ligand-specific manner, thus identifying residues in the MOR binding pocket that govern ligand bias. This increases our understanding of how ligand/receptor binding interactions can be translated into agonist-specific pathway activation. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  15. View southeast, stone sluice, top of lower standing section, showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southeast, stone sluice, top of lower standing section, showing row of cement piers in center, retaining wall to left, barge canal sluice to right - Glens Falls Feeder, Sluice, Along south side of Glens Falls Feeder between locks 10 & 20, Hudson Falls, Washington County, NY

  16. View southeast, stone sluice, top of upper standing section, showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southeast, stone sluice, top of upper standing section, showing cement piers over arch in foreground, foot of break at third drop in center, retaining wall to left, barge canal sluice to right - Glens Falls Feeder, Sluice, Along south side of Glens Falls Feeder between locks 10 & 20, Hudson Falls, Washington County, NY

  17. Thermal modeling of tanks 241-AW-101 and 241-AN-104 with the TEMPEST code

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Antoniak, Z.I.; Recknagle, K.P.

    The TEMPEST code was exercised in a preliminary study of double-shell Tanks 241 -AW-101 and 241-AN-104 thermal behavior. The two-dimensional model used is derived from our earlier studies on heat transfer from Tank 241-SY-101. Several changes were made to the model to simulate the waste and conditions in 241-AW-101 and 241-AN-104. The nonconvective waste layer was assumed to be 254 cm (100 in.) thick for Tank 241-AW-101, and 381 cm (150 in.) in Tank 241-AN-104. The remaining waste was assumed, for each tank, to consist of a convective layer with a 7.6-cm (3-inch) crust on top. The waste heat loadsmore » for 241-AW-101 and 241-AN-104 were taken to be 10 kW (3.4E4 Btu/hr) and 12 kW (4.0E4 Btu/hr), respectively. Present model predictions of maximum and convecting waste temperatures are within 1.7{degrees}C (3{degrees}F) of those measured in Tanks 241-AW-101 and 241-AN-104. The difference between the predicted and measured temperature is comparable to the uncertainty of the measurement equipment. These models, therefore, are suitable for estimating the temperatures within the tanks in the event of changing air flows, waste levels, and/or waste configurations.« less

  18. Residual waste from Hanford tanks 241-C-203 and 241-C-204. 2. Contaminant release model.

    PubMed

    Cantrell, Kirk J; Krupka, Kenneth M; Deutsch, William J; Lindberg, Michael J

    2006-06-15

    Release of U and 99Tc from residual sludge in Hanford waste tanks 241-C-203 and 241-C-204 atthe U.S. Department of Energy's (DOE) Hanford Site in southeastern Washington state was quantified by water-leaching, selective extractions, empirical solubility measurements, and thermodynamic modeling. A contaminant release model was developed based on these experimental results and solid-phase characterization results presented elsewhere. Uranium release was determined to be controlled by two phases and occurred in three stages. In the first stage, U release is controlled by the solubility of tejkaite, which is suppressed by high concentrations of sodium released from the dissolution of NaNO3 in the residual sludges. Equilibrium solubility calculations indicate the U released during this stage will have a maximum concentration of 0.021 M. When all the NaNO3 has dissolved from the sludge, the solubility of the remaining cejkaite will increase to 0.28 M. After cejkaite has completely dissolved, the majority of the remaining U is in the form of poorly crystalline Na2U2O7 [or clarkeite Na[(UO2)O(OH)](H20)0-1]. In contact with Hanford groundwater this phase is not stable, and becquerelite becomes the U solubility controlling phase, with a calculated equilibrium concentration of 1.2 x 10(-4) M. For Tc, a significant fraction of its concentration in the residual sludge was determined to be relatively insoluble (20 wt % for C-203 and 80 wt % for C-204). Because of the low concentrations of Tc in these sludge materials, the characterization studies did not identify any discrete Tc solids phases. Release of the soluble fraction of Tc was found to occur concomitantly with NO3-. It was postulated that a NaNO3-NaTcO4 solid solution could be responsible for this behavior. The Tc release concentrations for the soluble fraction were estimated to be 2.4 x 10-6 M for C-203 and 2.7 x 10(-5) M for C-204. Selective extraction results indicated that the recalcitrant fraction of Tc was

  19. Hanford Single-Shell Tank Leak Causes and Locations - 241-BY and 241-TY Farm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Girardot, Crystal L.; Harlow, Donald G.

    This document identifies 241-BY Tank Farm (BY Farm) and 241-TY Tank Farm (TY Farm) lead causes and locations for the 100 series leaking tanks (241-BY-103, 241-TY-103, 241-TY-104, 241-TY-105 and 241-TY-106) identified in RPP-RPT-43704, Hanford BY Farm Leak Assessments Report, and in RPP-RPT-42296, Hanford TY Farm Leak Assessments Report. This document satisfies the BY and TY Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  20. View east, stone sluice, beginning of lower standing section, showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View east, stone sluice, beginning of lower standing section, showing third drop, stone pier in center, cement piers to right - Glens Falls Feeder, Sluice, Along south side of Glens Falls Feeder between locks 10 & 20, Hudson Falls, Washington County, NY

  1. Process test plan, phase II: waste retrieval sluicing system emissions collection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    POWERS, R.L.

    1999-06-01

    This Process Test Plan is prepared to continue from HNF-3733 which was Phase I of the test. Supplemental operational controls and sampling requirements are defined to safely obtain gas samples from the 296-C-006 ventilation system stack during active operation of the sluicing equipment.

  2. Tank 241-AP-106, Grab samples, 6AP-98-1, 6AP-98-2 and 6AP-98-3 Analytical results for the final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    FULLER, R.K.

    1999-02-23

    This document is the final report for tank 241-AP-106 grab samples. Three grab samples 6AP-98-1, 6AP-98-2 and 6AP-98-3 were taken from riser 1 of tank 241-AP-106 on May 28, 1998 and received by the 222-S Laboratory on May 28, 1998. Analyses were performed in accordance with the ''Compatability Grab Sampling and Analysis Plan'' (TSAP) (Sasaki, 1998) and the ''Data Quality Objectives for Tank Farms Waste Compatability Program (DQO). The analytical results are presented in the data summary report. No notification limits were exceeded. The request for sample analysis received for AP-106 indicated that the samples were polychlorinated biphenyl (PCB) suspects.more » The results of this analysis indicated that no PCBs were present at the Toxic Substance Control Act (TSCA) regulated limit of 50 ppm. The results and raw data for the PCB analysis are included in this document.« less

  3. Hanford Tanks 241-C-203 and 241-C-204: Residual Waste Contaminant Release Model and Supporting Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deutsch, William J.; Krupka, Kenneth M.; Lindberg, Michael J.

    This report describes the development of release models for key contaminants that are present in residual sludge remaining after closure of Hanford Tanks 241-C-203 (C-203) and 241-C-204 (C-204). The release models were developed from data generated by laboratory characterization and testing of samples from these two tanks. Key results from this work are (1) future releases from the tanks of the primary contaminants of concern (99Tc and 238U) can be represented by relatively simple solubility relationships between infiltrating water and solid phases containing the contaminants; and (2) high percentages of technetium-99 in the sludges (20 wt% in C-203 and 75more » wt% in C-204) are not readily water leachable, and, in fact, are very recalcitrant. This is similar to results found in related studies of sludges from Tank AY-102. These release models are being developed to support the tank closure risk assessments performed by CH2M HILL Hanford Group, Inc., for the U.S. Department of Energy.« less

  4. View north, stone sluice, head of 40foot break, showing failed ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View north, stone sluice, head of 40-foot break, showing failed arch in center, stone pier in center right, cement piers to upper left, retaining wall in background - Glens Falls Feeder, Sluice, Along south side of Glens Falls Feeder between locks 10 & 20, Hudson Falls, Washington County, NY

  5. Project W-320 acceptance test report for AY-farm electrical distribution

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bevins, R.R.

    1998-04-02

    This Acceptance Test Procedure (ATP) has been prepared to demonstrate that the AY-Farm Electrical Distribution System functions as required by the design criteria. This test is divided into three parts to support the planned construction schedule; Section 8 tests Mini-Power Pane AY102-PPI and the EES; Section 9 tests the SSS support systems; Section 10 tests the SSS and the Multi-Pak Group Control Panel. This test does not include the operation of end-use components (loads) supplied from the distribution system. Tests of the end-use components (loads) will be performed by other W-320 ATPs.

  6. MicroRNA-320c inhibits tumorous behaviors of bladder cancer by targeting Cyclin-dependent kinase 6

    PubMed Central

    2014-01-01

    Background Increasing evidence has suggested that dysregulation of microRNAs (miRNAs) could contribute to human disease including cancer. Previous miRNA microarray analysis illustrated that miR-320c is down-regulated in various cancers. However, the roles of miR-320c in human bladder cancer have not been well elucidated. Therefore, this study was performed to investigate the biological functions and molecular mechanisms of miR-320c in human bladder cancer cell lines, discussing whether it could be a therapeutic biomarker of bladder cancer in the future. Methods Two human bladder cancer cell lines and samples from thirteen patients with bladder cancer were analyzed for the expression of miR-320c by quantitative RT-PCR. Over-expression of miR-320c was established by transfecting mimics into T24 and UM-UC-3. Cell proliferation and cell cycle were assessed by cell viability assay, flow cytometry and colony formation assay. Cell motility ability was evaluated by transwell assay. The target gene of miR-320c was determined by luciferase assay, quantitative RT-PCR and western blot. The regulation of cell cycle and mobility by miR-320c was analyzed by western blot. Results We observed that miR-320c was down-regulated in human bladder cancer tissues and bladder cancer cell lines T24 and UM-UC-3. Over-expression of miR-320c could induce G1 phase arrest in UM-UC-3 and T24 cells, and subsequently inhibited cell growth. We also indentified miR-320c could impair UM-UC-3 and T24 cell motility. In addition, we identified CDK6, a cell cycle regulator, as a novel target of miR-320c. Moreover, we demonstrated miR-320c could induce bladder cancer cell cycle arrest and mobility via regulating CDK6. We also observed that inhibition of miR-320c or restoration of CDK6 in miR-320c-over-expressed bladder cancer cells partly reversed the suppressive effects of miR-320c. Conclusions miR-320c could inhibit the proliferation, migration and invasion of bladder cancer cells via regulating CDK6

  7. Generation of 320 mW at 10.20 μm based on CdSe long-wave infrared crystal

    NASA Astrophysics Data System (ADS)

    Wang, Jian; Yuan, Ligang; Zhang, Yingwu; Chen, Guo; Cheng, Hongjuan; Gao, Yanzhao

    2018-06-01

    CdSe single crystal, with the sizes of ∼54 mm in diameter and ∼25 mm in length, was grown by a high pressure vertical gradient freeze (HPVGF) technique using (0 0 1)-oriented seed. The CdSe crystal was characterized with transmission spectrophotometer. The transmission spectra showed that the infrared transmission was above 68% and the mean absorption coefficient was 0.041 cm-1 in the range of 2.5-20 μm. Using fabricated CdSe crystal with the dimensions of 6 mm × 10 mm × 44 mm, we demonstrated an optical parametric oscillator (OPO) pumped by a 2.05 μm Ho:YLF laser at a pulse repetition frequency of 5 kHz. Up to 320 mW output was obtained at the idler wavelength of 10.20 μm with a pump power of 18.06 W. 320 mW at 10.20 μm, to our knowledge, was the highest power obtained with a 2.05 μm laser-pumped CdSe OPO.

  8. Hanford Tanks 241-C-203 and 241 C 204: Residual Waste Contaminant Release Model and Supporting Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deutsch, William J.; Krupka, Kenneth M.; Lindberg, Michael J.

    This report was revised in May 2007 to correct 90Sr values in Chapter 3. The changes were made on page 3.9, paragraph two and Table 3.10; page 3.16, last paragraph on the page; and Tables 3.21 and 3.31. The rest of the text remains unchanged from the original report issued in October 2004. This report describes the development of release models for key contaminants that are present in residual sludge remaining after closure of Hanford Tanks 241-C-203 (C-203) and 241-C-204 (C-204). The release models were developed from data generated by laboratory characterization and testing of samples from these two tanks.more » Key results from this work are (1) future releases from the tanks of the primary contaminants of concern (99Tc and 238U) can be represented by relatively simple solubility relationships between infiltrating water and solid phases containing the contaminants; and (2) high percentages of technetium-99 in the sludges (20 wt% in C-203 and 75 wt% in C-204) are not readily water leachable, and, in fact, are very recalcitrant. This is similar to results found in related studies of sludges from Tank AY-102. These release models are being developed to support the tank closure risk assessments performed by CH2M HILL Hanford Group, Inc., for the U.S. Department of Energy.« less

  9. Integrated Geophysical Survey on Deák Ferenc Sluice in Hungary

    NASA Astrophysics Data System (ADS)

    Kanli, A. I.

    2015-12-01

    ALI ISMET KANLI1*, G. TALLER2, Z. PRONAY2, P. TILDY2, P. NAGY3, E. TOROS2 *1Istanbul University, Turkey, kanli@istanbul.edu.tr, 2Geological and Geophysical Institute of Hungary,3MinGeo, Hungary The Ferenc Channel is one of the main irrigation and ship channel in south of Hungary, existing from 1801. The water level is controlled by the Deák Ferenc Sluice in the channel which was constructed in 1875. At that time, the sluice was unique in Europe with its two channels and brick-walls. The west channel was used for controlling the amount of water and the east channel was used for shipping. In the study, before starting to the restoration and reinforcement plannings at the sluice, non-destructive geophysical investigations were executed. In the first stage, ultra-high frequency seismic (80 kHz) and acoustic (5 kHz) investigations of the floor slab were carried out from a boat on the water level. Due to the water level was approximately 2 m, we could use the advantage of the water ensuring very good coupling with seismic sensors for high frequency seismic and acoustic measurements. In the second stage, resistivity measurements were carried out in the eastern part of the sluice which was used as the shipping channel. Three profiles were measured to map the resistivity distribution of the slab. In the third stage, for better understanding the stability conditions of the walls and easy to compare with the data of GPR measurements, the wall of the sluice were investigated by a simple seismic direct wave method using seismic P-waves for mapping seismic velocities. The last stage of the survey was the GPR measurements that were carried out both on the walls and on the slab of the sluice. During the investigation, the channels were empty and without water. The integrated survey and the interpretation of the results showed us that there were some faults, cracks and voids in the slab existed in the whole grossness of the slab and the brick walls were builded from inhomogenous

  10. Study on ecological regulation of coastal plain sluice

    NASA Astrophysics Data System (ADS)

    Yu, Wengong; Geng, Bing; Yu, Huanfei; Yu, Hongbo

    2018-02-01

    Coastal plains are densely populated and economically developed, therefore their importance is self-evident. However, there are some problems related with water in coastal plains, such as low flood control capacity and severe water pollution. Due to complicated river network hydrodynamic force, changeable flow direction and uncertain flood concentration and propagation mechanism, it is rather difficult to use sluice scheduling to realize flood control and tackle water pollution. On the base of the measured hydrological data during once-in-a-century Fitow typhoon in 2013 in Yuyao city, by typical analysis, theoretical analysis and process simulation, some key technologies were researched systematically including plain river network sluice ecological scheduling, “one tide” flood control and drainage scheduling and ecological running water scheduling. In the end, single factor health diagnostic evaluation, unit hydrograph of plain water level and evening tide scheduling were put forward.

  11. The Real-Time Processing of Sluiced Sentences

    ERIC Educational Resources Information Center

    Poirier, Josee; Wolfinger, Katie; Spellman, Lisa; Shapiro, Lewis P.

    2010-01-01

    Ellipsis refers to an element that is absent from the input but whose meaning can nonetheless be recovered from context. In this cross-modal priming study, we examined the online processing of Sluicing, an ellipsis whose antecedent is an entire clause: "The handyman threw a book to the programmer but I don't know which book" the handyman threw to…

  12. DETAIL OF VALVE TOWER SHOWING SLUICE GATE ON EAST SIDE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL OF VALVE TOWER SHOWING SLUICE GATE ON EAST SIDE OF TOWER. VIEW FACING WEST - Schofield Barracks Military Reservation, Ku Tree Reservoir, Valve Tower, Kalakoa Stream, East Range, Wahiawa, Honolulu County, HI

  13. Experimental analysis of the impact of sluice regulation on water quality in the highly polluted Huai River Basin, China.

    PubMed

    Zuo, Qiting; Chen, Hao; Dou, Ming; Zhang, Yongyong; Li, Dongfeng

    2015-07-01

    Impact assessment of sluice regulation on water quality is one of the crucial tasks in the present river management. However, research difficulties remain because of insufficient in situ data and numerous influencing factors in aquatic environments. The Huaidian Sluice, the main control sluice of the Shaying River, China, was selected for this study. Three field experimental programs were designed and carried out to analyze spatial and temporal variations in water quality parameters under various sluice regulation conditions and to explore the impacts of regulation mechanisms on water quality. Monitoring data were used to simulate water quality under different scenarios by the water quality analysis simulation program (WASP). Results demonstrate that the influences of sluice regulation on permanganate index (CODMn) and ammonia nitrogen (NH4-N) concentrations (indicators of water quality) were complex and nonlinear and presented different trends of increase or decrease from different regulation modes. Gate openings of different widths and different flow rates affected CODMn and NH4-N concentrations differently. Monitoring results and numerical simulation results indicate that the sluice opening should be small. Flow discharge through the sluice should be greater than 10 m(3) s and less than 60 m(3) s to maintain low CODMn concentrations, and discharge should be low (e.g., 14 m(3) s) to maintain low NH4-N concentrations. This research provides an experimental basis for further research on the construction of water quality models and for the development of reasonable regulations on water quality and quantity.

  14. sts106-s-005

    NASA Image and Video Library

    2000-09-08

    STS106-S-005 (8 September 2000) --- This distant view of the STS-106 liftoff was photographed across marsh waters around Mosquito Lagoon and Banana Creek, looking toward the Atlantic Ocean. The perfect on-time liftoff of the Space Shuttle Atlantis occurred at 8:45:47 a.m. (EDT), September 8, 2000. Onboard the shuttle were astronauts Terrence W. Wilcutt, Scott D. Altman, Edward T. Lu, Richard A. Mastracchio and Daniel C. Burbank, along with cosmonauts Yuri I. Malenchenko and Boris V. Morukov who represent the Russian Aviation and Space Agency.

  15. 12. CANAL SLUICE GATE LOCATED 150' WEST OF POWER PLANT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. CANAL SLUICE GATE LOCATED 150' WEST OF POWER PLANT. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  16. Solid Phase Characterization of Tank 241-C-105 Grab Samples

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ely, T. M.; LaMothe, M. E.; Lachut, J. S.

    The solid phase characterization (SPC) of three grab samples from single-shell Tank 241-C-105 (C-105) that were received at the laboratory the week of October 26, 2015, has been completed. The three samples were received and broken down in the 11A hot cells.

  17. Identification of key factors affecting the water pollutant concentration in the sluice-controlled river reaches of the Shaying River in China via statistical analysis methods.

    PubMed

    Dou, Ming; Zhang, Yan; Zuo, Qiting; Mi, Qingbin

    2015-08-01

    The construction of sluices creates a strong disturbance in water environmental factors within a river. The change in water pollutant concentrations of sluice-controlled river reaches (SCRRs) is more complex than that of natural river segments. To determine the key factors affecting water pollutant concentration changes in SCRRs, river reaches near the Huaidian Sluice in the Shaying River of China were selected as a case study, and water quality monitoring experiments based on different regulating modes were implemented in 2009 and 2010. To identify the key factors affecting the change rates for the chemical oxygen demand of permanganate (CODMn) and ammonia nitrogen (NH3-N) concentrations in the SCRRs of the Huaidian Sluice, partial correlation analysis, principal component analysis and principal factor analysis were used. The results indicate four factors, i.e., the inflow quantity from upper reaches, opening size of sluice gates, water pollutant concentration from upper reaches, and turbidity before the sluice, which are the common key factors for the CODMn and NH3-N concentration change rates. Moreover, the dissolved oxygen before a sluice is a key factor for the permanganate concentration from CODMn change rate, and the water depth before a sluice is a key factor for the NH3-N concentration change rate. Multiple linear regressions between the water pollutant concentration change rate and key factors were established via multiple linear regression analyses, and the quantitative relationship between the CODMn and NH3-N concentration change rates and key affecting factors was analyzed. Finally, the mechanism of action for the key factors affecting the water pollutant concentration changes was analyzed. The results reveal that the inflow quantity from upper reaches, opening size of sluice gates, permanganate concentration from CODMn from upper reaches and dissolved oxygen before the sluice have a negative influence and the turbidity before the sluice has a positive

  18. 1. Photocopy of a drawing (original in the Collection of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopy of a drawing (original in the Collection of the PL&C, Shelf 118, Drawing 241)--February 1888--PLAN OF SLUICE WAYS AS RECONSTRUCTED IN 1887 - Pawtucket Canal, Lower Locks, Lowell, Middlesex County, MA

  19. Microstructure and Mechanical Properties of W-ZrC Composites Synthesized by Reactive Melt Infiltration of Zr2Cu into Porous Preforms from Partially Carburized W Powders

    NASA Astrophysics Data System (ADS)

    Wang, Dong; Wang, Yu-Jin; Huo, Si-Jia; Zhao, Yan-Wei; Ouyang, Jia-Hu; Song, Gui-Ming; Zhou, Yu

    2018-03-01

    W-ZrC composites with different W contents from 48 to 73 vol.% have been synthesized by reactive melt infiltration of Zr2Cu melt into porous preforms from partially carburized W powders at 1300 °C for 1 h in vacuum. The influences of carbon content and porosity in the preforms on microstructure and mechanical properties of W-ZrC composites are investigated. Cold isostatic pressing followed by pre-sintering process is used to produce porous preforms with suitable porosities of 53.6-47% under a pressure of 100 MPa to allow sufficient penetration of Zr2Cu melt into the preforms. Small amounts of Cu-rich phases form in the synthesized W-ZrC composites after a complete reaction of y/2xZr2Cu(l) + WC y (s) = y/xZrC x (s) + W(s) + y/2xCu(l). These Cu-rich phases are distributed not only at the phase boundaries of W matrix and ZrC grains, but also in the interior of ZrC x grains. With decreasing W content from 73 to 48 vol.% in the W-ZrC composites, the flexural strength and fracture toughness increase from 519 to 657 MPa and from 9.1 to 10.6 MPa m1/2, respectively.

  20. A MPEG-4 encoder based on TMS320C6416

    NASA Astrophysics Data System (ADS)

    Li, Gui-ju; Liu, Wei-ning

    2013-08-01

    Engineering and products need to achieve real-time video encoding by DSP, but the high computational complexity and huge amount of data requires that system has high data throughput. In this paper, a real-time MPEG-4 video encoder is designed based on TMS320C6416 platform. The kernel is the DSP of TMS320C6416T and FPGA chip f as the organization and management of video data. In order to control the flow of input and output data. Encoded stream is output using the synchronous serial port. The system has the clock frequency of 1GHz and has up to 8000 MIPS speed processing capacity when running at full speed. Due to the low coding efficiency of MPEG-4 video encoder transferred directly to DSP platform, it is needed to improve the program structure, data structures and algorithms combined with TMS320C6416T characteristics. First: Design the image storage architecture by balancing the calculation spending, storage space cost and EDMA read time factors. Open up a more buffer in memory, each buffer cache 16 lines of video data to be encoded, reconstruction image and reference image including search range. By using the variable alignment mode of the DSP, modifying the definition of structure variables and change the look-up table which occupy larger space with a direct calculation array to save memory space. After the program structure optimization, the program code, all variables, buffering buffers and the interpolation image including the search range can be placed in memory. Then, as to the time-consuming process modules and some functions which are called many times, the corresponding modules are written in parallel assembly language of TMS320C6416T which can increase the running speed. Besides, the motion estimation algorithm is improved by using a cross-hexagon search algorithm, The search speed can be increased obviously. Finally, the execution time, signal-to-noise ratio and compression ratio of a real-time image acquisition sequence is given. The experimental

  1. Field calibration of submerged sluice gates in irrigation canals

    USDA-ARS?s Scientific Manuscript database

    Four rectangular sluice gates were calibrated for submerged-flow conditions using nearly 16,000 field-measured data points on Canal B of the B-XII irrigation scheme in Lebrija, Spain. Water depth and gate opening values were measured using acoustic sensors at each of the gate structures, and the dat...

  2. Tank 241-C-112 vapor sampling and analysis tank characterization report. Revision 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huckaby, J.L.

    1995-05-31

    Tank 241-C-112 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in {open_quotes}Program Plan for the Resolution of Tank Vapor Issues.{close_quotes} Tank 241-C-112 was vapor sampled in accordance with {open_quotes}Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution.{close_quotes}

  3. 75 FR 10026 - Proposed Collection; Comment Request for Forms W-2, W-2c, W-2AS, W-2GU, W-2VI, W-3, W-3c, W-3cPR...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ... Wage and Tax Statements), W-3PR (Informe de Comprobantes de Retencion), W-3cPR (Transmission de Comprobantes de Retencion Corregidos), and W-3SS (transmittal of Wage and Tax Staements). OMB Number: 1545-0008... Actions: There are no changes being made to the form at this time. Type of Review: Extension of a...

  4. Project W-211 Initial Tank Retrieval Systems (ITRS) Description of Operations for 241-AZ-102

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    BRIGGS, S.R.

    2000-02-25

    The primary purpose of the Initial Tank Retrieval Systems (ITRS) is to provide systems for retrieval of radioactive wastes stored in underground double-shell tanks (DSTs) for transfer to alternate storage, evaporation, pretreatment or treatment, while concurrently reducing risks associated with safety watch list and other DSTs. This Description of Operation (DOO) defines the control philosophy for the waste retrieval system for Tank 241-AZ-102 (AZ-102). This DOO provides a basis for the detailed design of the Project W-211 Retrieval Control System (RCS) for AZ-102 and also establishes test criteria for the RCS.

  5. The Paleohydrology of Sluice Pond, NE Massachusetts, and its Regional Significance

    EPA Science Inventory

    Seismic, pollen, stable isotope and lithologic stratigraphies of Sluice Pond, northeastern Massachusetts, were investigated to reconstruct local climate conditions fromthe latest Pleistocene to present. We present a new lake-level curve, constrained largely by acoustic reflectors...

  6. 49 CFR Appendix C to Part 241 - Geographical Boundaries of FRA's Regions and Addresses of FRA's Regional Headquarters

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Geographical Boundaries of FRA's Regions and Addresses of FRA's Regional Headquarters C Appendix C to Part 241 Transportation Other Regulations Relating... STATES LOCATIONAL REQUIREMENT FOR DISPATCHING OF UNITED STATES RAIL OPERATIONS Pt. 241, App. C Appendix C...

  7. 49 CFR Appendix C to Part 241 - Geographical Boundaries of FRA's Regions and Addresses of FRA's Regional Headquarters

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Geographical Boundaries of FRA's Regions and Addresses of FRA's Regional Headquarters C Appendix C to Part 241 Transportation Other Regulations Relating... STATES LOCATIONAL REQUIREMENT FOR DISPATCHING OF UNITED STATES RAIL OPERATIONS Pt. 241, App. C Appendix C...

  8. 49 CFR Appendix C to Part 241 - Geographical Boundaries of FRA's Regions and Addresses of FRA's Regional Headquarters

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Geographical Boundaries of FRA's Regions and Addresses of FRA's Regional Headquarters C Appendix C to Part 241 Transportation Other Regulations Relating... STATES LOCATIONAL REQUIREMENT FOR DISPATCHING OF UNITED STATES RAIL OPERATIONS Pt. 241, App. C Appendix C...

  9. Tank characterization report for single-shell tank 241-C-109

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Simpson, B.C.

    1997-05-23

    One of the major functions of the Tank Waste Remediation System (TWRS) is to characterize wastes in support of waste management and disposal activities at the Hanford Site. Analytical data from sampling and analysis, along with other available information about a tank, are compiled and maintained in a tank characterization report (TCR). This report and its appendices serve as the TCR for single-shell tank 241-C-109. The objectives of this report are: (1) to use characterization data in response to technical issues associated with tank 241 C-109 waste; and (2) to provide a standard characterization of this waste in terms ofmore » a best-basis inventory estimate. The response to technical issues is summarized in Section 2.0, and the best-basis inventory estimate is presented in Section 3.0. Recommendations regarding safety status and additional sampling needs are provided in Section 4.0. Supporting data and information are contained in the appendices.« less

  10. 13. Photographic copy of original Design For New Sluice Gate ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Photographic copy of original Design For New Sluice Gate drawing, date and engineer unknown (original in possession of United States Department of Agriculture-Forest Service-Allegheny National Forest). - Loleta Recreation Area, Lower Dam, 6 miles Southeast of interesection of State Route 24041 & State Route 66, Loleta, Elk County, PA

  11. STS-106 TCDT Photo Opportunity

    NASA Technical Reports Server (NTRS)

    2000-01-01

    STS-106 crewmembers Commander Terrence W. Wilcutt, Pilot Scott D. Altman, and Mission Specialists Daniel C. Burbank, Edward T. Lu, Richard A. Mastracchio, Yuri Ivanovich Malenchenko, and Boris V. Morukov are seen during the Terminal Countdown and Demonstration Test (TCDT) activity of meeting the press. Each crewmember introduces himself and then they answer questions from the press about the upcoming mission.

  12. 32 CFR 320.11 - Penalties.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Penalties. 320.11 Section 320.11 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.11 Penalties. The Privacy Act of 1974 (5 U.S.C...

  13. 32 CFR 320.11 - Penalties.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Penalties. 320.11 Section 320.11 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.11 Penalties. The Privacy Act of 1974 (5 U.S.C...

  14. 32 CFR 320.11 - Penalties.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Penalties. 320.11 Section 320.11 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.11 Penalties. The Privacy Act of 1974 (5 U.S.C...

  15. Environmental management through sluice gated bed-dam: a revived strategy for the control of Anopheles fluviatilis breeding in streams

    PubMed Central

    Sahu, S.S.; Gunasekaran, K.; Jambulingam, P.

    2014-01-01

    Background & objectives: Integrated vector management (IVM) emphasizes sustainable eco-friendly methods and minimal use of chemicals. In this context, the present study highlights the environmental control of breeding of Anopheles fluviatilis, the primary malaria vector, through water management in a natural stream in Koraput district, Odisha, India. Methods: The District Rural Development Agency (DRDA), Koraput, constructed two bed-dams across streams, one in Barigaon and the other in Pipalapodar village. The bed-dam in the former village was fitted with two sluice gates whereas the bed dam constructed in the latter village was without the sluice gate. The sluice gates were opened once in a week on a fixed day to flush out the water from the dam. Anopheles immatures were sampled systematically in the streams using a dipper for density measurement and species composition. Results: There was a reduction of 84.9 per cent in the proportion of positive dips for Anopheles larvae/pupae and a reduction of 98.4 per cent in immature density (number/dip) of An. fluviatilis in the experimental downstream compared to the control following opening of the sluice gates. Interpretation & conclusions: Our findins showed that opening of sluice gates of the bed-dam regularly once in a week resulted in the control of vector breeding in the downstream due to the flushing effect of the water released with a high flow from the bed-dam that stagnated water in the upstream. The outcome of the study encourages upscaling this measure to other areas, wherever feasible. PMID:25297364

  16. Vapor characterization of Tank 241-C-103

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huckaby, J.L.; Story, M.S.

    The Westinghouse Hanford Company Tank Vapor Issue Resolution Program has developed, in cooperation with Northwest Instrument Systems, Inc., Oak Ridge National Laboratory, Oregon Graduate Institute of Science and Technology, Pacific Northwest Laboratory, and Sandia National Laboratory, the equipment and expertise to characterize gases and vapors in the high-level radioactive waste storage tanks at the Hanford Site in south central Washington State. This capability has been demonstrated by the characterization of the tank 241-C-103 headspace. This tank headspace is the first, and for many reasons is expected to be the most problematic, that will be characterized (Osborne 1992). Results from themore » most recent and comprehensive sampling event, sample job 7B, are presented for the purpose of providing scientific bases for resolution of vapor issues associated with tank 241-C-103. This report is based on the work of Clauss et al. 1994, Jenkins et al. 1994, Ligotke et al. 1994, Mahon et al. 1994, and Rasmussen and Einfeld 1994. No attempt has been made in this report to evaluate the implications of the data presented, such as the potential impact of headspace gases and vapors to tank farm workers health. That and other issues will be addressed elsewhere. Key to the resolution of worker health issues is the quantitation of compounds of toxicological concern. The Toxicology Review Panel, a panel of Pacific Northwest Laboratory experts in various areas, of toxicology, has chosen 19 previously identified compounds as being of potential toxicological concern. During sample job 7B, the sampling and analytical methodology was validated for this preliminary list of compounds of toxicological concern. Validation was performed according to guidance provided by the Tank Vapor Conference Committee, a group of analytical chemists from academic institutions and national laboratories assembled and commissioned by the Tank Vapor Issue Resolution Program.« less

  17. STS106-s-015

    NASA Image and Video Library

    2000-09-08

    STS106-S-015 (8 September 2000) --- The Space Shuttle Atlantis streaks into the sky on mission STS-106 after a perfect on-time launch at 8:45:47 a.m. (EDT), September 8, 2000. Blue mach diamonds are barely visible beneath the main engine nozzles. On the 11-day mission to the International Space Station, the seven-member crew will perform support tasks on orbit; transfer supplies and prepare the living quarters in the newly arrived Zvezda Service Module. The first long-duration crew is due to arrive at the Station in late fall. Onboard the spacecraft were astronauts Terrance W. Wilcutt, Scott D. Altman, Edward T. Lu, Richard A. Mastracchio and Daniel C. Burbank, along with cosmonauts Yuri I. Malenchenko and Boris Morukov, both of whom represent Rosaviakosmos.

  18. 33 CFR 241.3 - References.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Information Services, 5285 Port Royal Road, Springfield, VA 22161. References (a), (b) and (c) may be reviewed... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false References. 241.3 Section 241.3... CONTROL COST-SHARING REQUIREMENTS UNDER THE ABILITY TO PAY PROVISION § 241.3 References. References cited...

  19. Project W-314 acceptance test report HNF-4643 for HNF-4642 241-AN-A valve pit manifold valves and position indication for project W-314

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    HAMMERS, J.S.

    1999-09-22

    The purpose of the test was to verify that the AN Tank Farm Manifold Valves can be manually manipulated to the required operating position and that the electrical and visual indications accurately reflect that position. Physical locking devices were also verified to function. The Acceptance Test Procedure HNF-4642, 241-AN-A Valve Pit Manifold Valves and Position Indication was conducted between 23 June and 10 August 1999 at the 200E AN Tank Farm. The test has no open test exceptions. The test was conducted prior to final engineering ''as built'' activities being completed, this had an impact on the procedure and testmore » results, ECN 653752 was written to correct the mismatch between the procedure and actual field conditions. P&ID H-14-100941 was changed via ECN-W-314-4C-120. All components, identified in the procedure, were not found to be labeled and identified as written in the procedure, temporary tags were used for operational identification. A retest of valve ANA-WT-V 318 was required because it was removed from its installed position and modified after testing was completed.« less

  20. Investigation of Tank 241-AN-101 Floating Solids

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kraft, Douglas P.; Meznarich, H. K.

    Tank 241-AN-101 is the receiver tank for retrieval of several C-Farms waste tanks, including Tanks 241-C-102 and 241-C-111. Tank 241 C 111 received first-cycle decontamination waste from the bismuth phosphate process and Plutonium and Uranium Extraction cladding waste, as well as hydraulic fluid. Three grab samples, 1AN-16-01, 1AN-16-01A, and 1AN-16-01B, were collected at the surface of Tank 241-AN-101 on April 25, 2016, after Tank 241-C-111 retrieval was completed. Floating solids were observed in the three grab samples in the 11A hot cell after the samples were received at the 222-S Laboratory. Routine chemical analyses, solid phase characterization on the floatingmore » and settled solids, semivolatile organic analysis mainly on the aqueous phase for identification of degradation products of hydraulic fluids were performed. Investigation of the floating solids is reported.« less

  1. Actor coalitions and implementation in strategic delta planning: Opening the Haringvliet sluices in the Netherlands

    NASA Astrophysics Data System (ADS)

    Vermoolen, Myrthe; Hermans, Leon

    2016-04-01

    The sustained development of urbanizing deltas is influenced by natural and societal processes. These processes are characterized by their long time span, in which conflicting interests of different stakeholders have to be reconciled. Reaching consent between actors is a challenge itself, but maintaining this consent throughout different stages of strategic planning - from advocacy and agenda setting to implementation - over these long periods of time is even more difficult. The implementation stage still includes many different actors involved, some of which are different than the ones who agreed before, due to both the long run of the strategic delta planning, and to a shift of tasks and responsibilities. Thus, implementation of strategic plans often features delays, deviations of agreed plans and unintended outcomes. A key question therefore is how coalition dynamics in (pre-)planning stages influence and are influenced by the coalition dynamics during implementation. The different stages in strategic planning are often studied from either a plan formulation or an implementation perspective, but the connection between the two proves an important bottleneck for strategic planning in deltas. For instance, many building with nature solutions are still in their pilot-phase, and their upscaling can profit from lessons concerning past implementation efforts. The proposed contribution will use the case of the management of the Dutch Haringvliet sluices and the decision ('Kierbesluit') in 2000 to put these sluices ajar, to study the link between the different strategic delta planning stages and the role of the formation and change of actor coalitions herein. With the completion of the Haringvliet dam with outlet sluices in 1970, the Haringvliet estuary of the rivers Rhine and Meuse was closed off from the sea, creating a fresh water lake. This was done to make the Dutch Southwest delta safe from flooding, and had positive effects for agricultural water supply and

  2. 33 CFR 320.3 - Related laws.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Related laws. 320.3 Section 320.3... REGULATORY POLICIES § 320.3 Related laws. (a) Section 401 of the Clean Water Act (33 U.S.C. 1341) requires... fullest extent possible: (1) The policies, regulations, and public laws of the United States shall be...

  3. Project W-211, initial tank retrieval systems, description of operations for 241-AP-102 and 241-AP-104

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    RIECK, C.A.

    1999-02-25

    The primary purpose of the Initial Tank Retrieval Systems (ITRS) is to provide systems for retrieval of radioactive wastes stored in underground double-shell tanks (DSTS) for transfer to alternate storage, evaporation, pretreatment or treatment, while concurrently reducing risks associated with safety watch list and other DSTs. This Description of Operations (DOO) defines the control philosophy for the waste retrieval system for tanks 241-AP-102 (AP-102) and 241-AP-104 (AP-104). This DOO will provide a basis for the detailed design of the Retrieval Control System (RCS) for AP-102 and AP-104 and establishes test criteria for the RCS. The test criteria will be usedmore » during qualification testing and acceptance testing to verify operability.« less

  4. 49 CFR 241.17 - Preemptive effect.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Preemptive effect. 241.17 Section 241.17 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... OPERATIONS § 241.17 Preemptive effect. Under 49 U.S.C. 20106, the regulations in this part preempt any State...

  5. 49 CFR 241.19 - Information collection.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Information collection. 241.19 Section 241.19... OPERATIONS § 241.19 Information collection. (a) The information collection requirements of this part are... (44 U.S.C. 3501 et seq.). (b) The information collection requirements are found in the following...

  6. Tribological Behavior of Plasma-Sprayed Al2O3-20 wt.%TiO2 Coating

    NASA Astrophysics Data System (ADS)

    Cui, Shiyu; Miao, Qiang; Liang, Wenping; Zhang, Zhigang; Xu, Yi; Ren, Beilei

    2017-05-01

    Al2O3-20 wt.% TiO2 ceramic coatings were deposited on the surface of Grade D steel by plasma spraying of commercially available powders. The phases and the microstructures of the coatings were investigated by x-ray diffraction and scanning electron microscopy, respectively. The Al2O3-20 wt.% TiO2 composite coating exhibited a typical inter-lamellar structure consisting of the γ-Al2O3 and the Al2TiO5 phases. The dry sliding wear behavior of the coating was examined at 20 °C using a ball-on-disk wear tester. The plasma-sprayed coating showed a low wear rate ( 4.5 × 10-6 mm3 N-1 m-1), which was <2% of that of the matrix ( 283.3 × 10-6 mm3 N-1 m-1), under a load of 15 N. In addition, the tribological behavior of the plasma-sprayed coating was analyzed by examining the microstructure after the wear tests. It was found that delamination of the Al2TiO5 phase was the main cause of the wear during the sliding wear tests. A suitable model was used to simulate the wear mechanism of the coating.

  7. 34 CFR 106.71 - Procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Expenditures, 106.41(c) Facilities, 106.41(c) Travel, 106.41(c) Scholarships, [64, 65]; 106.37(d) General, [69....56, 106.39 Part-time employees, [89] G Grievance Procedure, see “Designation of responsible employee...]; 106.15(d) Purpose of Regulation, [13]; 106.1 R Real Property, 106.2(g) Recruitment Employment...

  8. STS-106 crew poses for photos after landing

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The STS-106 crew poses for a photograph after a successful mission and landing. Standing, left to right, are Mission Specialists Yuri I. Malenchenko, Boris V. Morukov, Daniel C. Burbank and Richard A. Mastracchio; Pilot Scott D. Altman; Mission Specialist Edward T. Lu; and Commander Terrence W. Wilcutt. Main gear touchdown occurred on-time at 3:56:48 a.m. EDT. Atlantis and crew traveled 4.9 million miles on the 11-day, 19-hour, 11-minute STS-106 mission. During the mission to the International Space Station, the crew transferred nearly 5,000 pounds of equipment and supplies for use by the first resident crew expected to arrive in November. STS-106 was the 99th flight in the Shuttle program and the 22nd for Atlantis. STS-106 also marked the 15th nighttime landing in Shuttle history and the 23rd consecutive landing at KSC.

  9. C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.

    PubMed

    Mohanan, Vishnu; Nakata, Toru; Desch, A Nicole; Lévesque, Chloé; Boroughs, Angela; Guzman, Gaelen; Cao, Zhifang; Creasey, Elizabeth; Yao, Junmei; Boucher, Gabrielle; Charron, Guy; Bhan, Atul K; Schenone, Monica; Carr, Steven A; Reinecker, Hans-Christian; Daly, Mark J; Rioux, John D; Lassen, Kara G; Xavier, Ramnik J

    2018-03-09

    Polymorphisms in C1orf106 are associated with increased risk of inflammatory bowel disease (IBD). However, the function of C1orf106 and the consequences of disease-associated polymorphisms are unknown. Here we demonstrate that C1orf106 regulates adherens junction stability by regulating the degradation of cytohesin-1, a guanine nucleotide exchange factor that controls activation of ARF6. By limiting cytohesin-1-dependent ARF6 activation, C1orf106 stabilizes adherens junctions. Consistent with this model, C1orf106 -/- mice exhibit defects in the intestinal epithelial cell barrier, a phenotype observed in IBD patients that confers increased susceptibility to intestinal pathogens. Furthermore, the IBD risk variant increases C1orf106 ubiquitination and turnover with consequent functional impairments. These findings delineate a mechanism by which a genetic polymorphism fine-tunes intestinal epithelial barrier integrity and elucidate a fundamental mechanism of cellular junctional control. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

  10. Toxicologic evaluation of analytes from Tank 241-C-103

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mahlum, D.D.; Young, J.Y.; Weller, R.E.

    1994-11-01

    Westinghouse Hanford Company requested PNL to assemble a toxicology review panel (TRP) to evaluate analytical data compiled by WHC, and provide advice concerning potential health effects associated with exposure to tank-vapor constituents. The team`s objectives would be to (1) review procedures used for sampling vapors from tanks, (2) identify constituents in tank-vapor samples that could be related to symptoms reported by workers, (3) evaluate the toxicological implications of those constituents by comparison to establish toxicological databases, (4) provide advice for additional analytical efforts, and (5) support other activities as requested by WHC. The TRP represents a wide range of expertise,more » including toxicology, industrial hygiene, and occupational medicine. The TRP prepared a list of target analytes that chemists at the Oregon Graduate Institute/Sandia (OGI), Oak Ridge National Laboratory (ORNL), and PNL used to establish validated methods for quantitative analysis of head-space vapors from Tank 241-C-103. this list was used by the analytical laboratories to develop appropriate analytical methods for samples from Tank 241-C-103. Target compounds on the list included acetone, acetonitrile, ammonia, benzene, 1, 3-butadiene, butanal, n-butanol, hexane, 2-hexanone, methylene chloride, nitric oxide, nitrogen dioxide, nitrous oxide, dodecane, tridecane, propane nitrile, sulfur oxide, tributyl phosphate, and vinylidene chloride. The TRP considered constituent concentrations, current exposure limits, reliability of data relative to toxicity, consistency of the analytical data, and whether the material was carcinogenic or teratogenic. A final consideration in the analyte selection process was to include representative chemicals for each class of compounds found.« less

  11. 46 CFR 120.320 - Generators and motors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Generators and motors. 120.320 Section 120.320 Shipping... and Distribution Systems § 120.320 Generators and motors. (a) Each generator and motor must be: (1) In... generator and motor must be designed for an ambient temperature of 50 °C (122 °F) except that: (1) If the...

  12. 46 CFR 120.320 - Generators and motors.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Generators and motors. 120.320 Section 120.320 Shipping... and Distribution Systems § 120.320 Generators and motors. (a) Each generator and motor must be: (1) In... generator and motor must be designed for an ambient temperature of 50 °C (122 °F) except that: (1) If the...

  13. MS Mastracchio uses the hand-held laser rangefinder during STS-106

    NASA Image and Video Library

    2000-09-18

    STS106-320-014 (10 September 2000) --- Astronaut Richard A. Mastracchio, mission specialist, uses a handheld laser device on the aft flight deck of the Space Shuttle Atlantis to track the range of the International Space Station during rendezvous operations.

  14. STS-106 crew poses for photos after landing

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Standing in front of the orbiter Atlantis after a successful landing at the Shuttle Landing Facility, the STS-106 crew greets the media and onlookers. Standing, left to right, are Mission Specialists Yuri I. Malenchenko, Boris V. Morukov, Daniel C. Burbank and Richard A. Mastracchio; Pilot Scott D. Altman; Mission Specialist Edward T. Lu; and Commander Terrence W. Wilcutt at the microphone. Main gear touchdown occurred on-time at 3:56:48 a.m. EDT. Atlantis and crew traveled 4.9 million miles on the 11-day, 19-hour, 11-minute STS-106 mission. During the mission to the International Space Station, the crew transferred nearly 5,000 pounds of equipment and supplies for use by the first resident crew expected to arrive in November. STs-106 was the 99th flight in the Shuttle program and the 22nd for Atlantis. STS-106 also marked the 15th nighttime landing in Shuttle history and the 23rd consecutive landing at KSC.

  15. Design of Alpha Voltaic Power Source Using Americium 241 (241Am) and Diamond with a Power Density of 10 mW/cm3

    DTIC Science & Technology

    2017-10-19

    GaN) was calculated and compared . Alpha-voltaic energy converters were designed in diamond and GaN based on the energy deposition calculations...Example Power Source Two example device designs are calculated and compared . A diamond device containing 2 charge collection regions (Schottky and p...ARL-TR-8189 ● OCT 2017 US Army Research Laboratory Design of Alpha-Voltaic Power Source Using Americium-241 (241Am) and Diamond

  16. 32 CFR 241.10 - Small business consideration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Small business consideration. 241.10 Section 241...) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.10 Small business... each year, at least 20 percent are from small business concerns (as defined by 5 U.S.C. 3703(e)(2)(A...

  17. 32 CFR 241.10 - Small business consideration.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Small business consideration. 241.10 Section 241...) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.10 Small business... each year, at least 20 percent are from small business concerns (as defined by 5 U.S.C. 3703(e)(2)(A...

  18. 32 CFR 241.10 - Small business consideration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Small business consideration. 241.10 Section 241...) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.10 Small business... assignments made each year, at least 20 percent are small business concerns (as defined by 5 U.S.C. 3703(e)(2...

  19. C-106 High-Level Waste Solids: Washing/Leaching and Solubility Versus Temperature Studies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    GJ Lumetta; DJ Bates; PK Berry

    This report describes the results of a test conducted by Battelle to assess the effects of inhibited water washing and caustic leaching on the composition of the Hanford tank C-106 high-level waste (HLW) solids. The objective of this work was to determine the composition of the C-106 solids remaining after washing with 0.01M NaOH or leaching with 3M NaOH. Another objective of this test was to determine the solubility of various C-106 components as a function of temperature. The work was conducted according to test plan BNFL-TP-29953-8,Rev. 0, Determination of the Solubility of HLW Sludge Solids. The test went accordingmore » to plan, with only minor deviations from the test plan. The deviations from the test plan are discussed in the experimental section.« less

  20. Theoretical studies on the electronic and optoelectronic properties of [A.2AP(w)/A*.2AP(WC)/C.2AP(w)/C*.2AP(WC)/C.A(w)/C*.A(WC)]-Au8 mismatch nucleobase complexes

    NASA Astrophysics Data System (ADS)

    Srivastava, Ruby

    2018-01-01

    The electronic and optoelectronic properties of [A.2AP(w)/A*.2AP(WC)/C.2AP(w)/C*.2AP(WC)/C.A(w)/ C*.A(WC)]-Au8 metal-mismatch nucleobase complexes are investigated by means of density functional theory and time-dependent methods. We selected these mispairs as 2-aminopurine (2AP) produces incorporation errors when binding with cytosine (C) into the wobble (w) C.2AP(w) mispair, and is tautomerised into Watson-Crick (WC)-like base mispair C*.2AP(WC) and less effectively produces A.2AP(w)/A*.2AP(WC) mispairs. The vertical ionisation potential, vertical electron affinity, hardness and electrophilicity index of these complexes have also been discussed. The modifications of energy levels and charge density distributions of the frontier orbitals are also analysed. The absorption spectra of these complexes lie in the visible region, which suggests their application in fluorescent-bio imaging. The mechanism of cooperativity effect is studied by molecular orbital potential (MEP), atoms-in-molecules (AIM) and natural bond orbital analyses. Most metalated pairs have smaller HOMO-LUMO band gaps than the isolated mismatch nucleobases which suggest interesting consequences for electron transfer through DNA duplexes.

  1. Disruption of c-Kit Signaling in Kit(W-sh/W-sh) Growing Mice Increases Bone Turnover.

    PubMed

    Lotinun, Sutada; Krishnamra, Nateetip

    2016-08-16

    c-Kit tyrosine kinase receptor has been identified as a regulator of bone homeostasis. The c-Kit loss-of-function mutations in WBB6F1/J-Kit(W/W-v) mice result in low bone mass. However, these mice are sterile and it is unclear whether the observed skeletal phenotype is secondary to a sex hormone deficiency. In contrast, C57BL/6J-Kit(W-sh)/(W-sh) (W(sh)/W(sh)) mice, which carry an inversion mutation affecting the transcriptional regulatory elements of the c-Kit gene, are fertile. Here, we showed that W(sh)/W(sh) mice exhibited osteopenia with elevated bone resorption and bone formation at 6- and 9-week-old. The c-Kit W(sh) mutation increased osteoclast differentiation, the number of committed osteoprogenitors, alkaline phosphatase activity and mineralization. c-Kit was expressed in both osteoclasts and osteoblasts, and c-Kit expression was decreased in W(sh)/W(sh)osteoclasts, but not osteoblasts, suggesting an indirect effect of c-Kit on bone formation. Furthermore, the osteoclast-derived coupling factor Wnt10b mRNA was increased in W(sh)/W(sh) osteoclasts. Conditioned medium from W(sh)/W(sh) osteoclasts had elevated Wnt10b protein levels and induced increased alkaline phosphatase activity and mineralization in osteoblast cultures. Antagonizing Wnt10b signaling with DKK1 or Wnt10b antibody inhibited these effects. Our data suggest that c-Kit negatively regulates bone turnover, and disrupted c-Kit signaling couples increased bone resorption with bone formation through osteoclast-derived Wnt 10 b.

  2. Double electron capture of {sup 106}Cd in the TGV-2 experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rukhadze, N. I.; Egorov, V. G.; Kovalik, A.

    2015-10-28

    A new experimental run of searching for EC/EC decay of {sup 106}Cd was performed at the Modane underground laboratory (4800 m w.e.) using the TGV-2 spectrometer and ∼23.2 g {sup 106}Cd with enrichment of 99.57%. The limit on 2νEC/EC decay of {sup 106}Cd - T{sub 1/2}(2νEC/EC) > 3.1×10{sup 20} y, at 90% C.L was obtained from the preliminary calculation of experimental data accumulated for 7018 h of measurement. The limits on the resonance neutrino-less double electron capture decay of {sup 106}Cd were obtained from the measurement of ∼23.2 g of {sup 106}Cd with the low-background HPGe spectrometer OBELIX lasted 395more » h - T{sub 1/2}(KL, 2741 keV) > 0.9×10{sup 20} y and T{sub 1/2}(KK, 2718 keV) > 1.4×10{sup 20} y at 90% C.L.« less

  3. Computer software configuration description, 241-AY and 241 AZ tank farm MICON automation system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Winkelman, W.D.

    This document describes the configuration process, choices and conventions used during the Micon DCS configuration activities, and issues involved in making changes to the configuration. Includes the master listings of the Tag definitions, which should be revised to authorize any changes. Revision 3 provides additional information on the software used to provide communications with the W-320 project and incorporates minor changes to ensure the document alarm setpoint priorities correctly match operational expectations.

  4. MD simulations of low energy deuterium irradiation on W, WC and W2C surfaces

    NASA Astrophysics Data System (ADS)

    Lasa, A.; Björkas, C.; Vörtler, K.; Nordlund, K.

    2012-10-01

    According to the present design beryllium (Be), tungsten (W) and carbon (C) will be the plasma facing materials in the ITER fusion reactor. Due to sputtering and subsequent re-deposition, mixing of these materials will occur. In this context, molecular dynamics simulations of cumulative, low energy and high flux D bombardment of pure W and tungsten carbides (WC, W2C) were carried out. The retention and sputtering properties as well as the structural deformation were analysed and comparisons to SDTrimSP simulations were made. Almost no tungsten is sputtered in the energy range considered and the D backscattering is lower in pure tungsten than in any of the tungsten carbides. In WC and W2C, the deuterium is mainly trapped forming small molecules, whereas mostly atomic D is present in pure W. The C sputtering increases with C content in the material, and shows a peak at the bombardment energy ˜50 eV, most likely due to the swift chemical sputtering mechanism. Pure W is seen to lose its crystallinity in the areas where D is present. After the D irradiation, the composition of both WC and W2C is mostly W in the topmost layers, due to preferential sputtering of C, an amorphous D-C mixture underneath and an undisturbed lattice in the rest of the cell.

  5. Hydrogen trapping under the effect of W-C mixed layers

    NASA Astrophysics Data System (ADS)

    Liu, N.; Huang, J.; Sato, K.; Xu, Q.; Shi, L. Q.; Wang, Y. X.

    2014-03-01

    The retention of hydrogen (H) isotope in plasma-facing materials (PFMs) is an important issue for next step fusion device. We used density functional theory (DFT) to study the chemical bonds of H in tungsten-carbon (W-C) mixed layers of tungsten surface, aiming to explore the retention behaviour of H in PFMs. The solubility of C in W was first calculated for revealing the phase components in W-C mixed layers. It was found that C has low solubility in W, which prefers to be segregated on the W surface. Vacancies can enhance the solution of C in W. This makes C appear somewhat carbide feature. Thus, W-C mixed layers should contain multiple phase components. H retention strongly depends on the phase components in the W-C mixed layers. The solution of C will suppress the retention of H in W no matter whether neighbouring vacancies are present, or not. Hydrocarbon precursors, which were observed in desorption experiments, prefer to form by means of H binding to C atoms in C amorphous, or in precipitators in the W-C mixed layers, while not in tungsten carbide phase or in W bulk. Our investigation reasonably explains the experimental results.

  6. Identification of four novel XPC mutations in two xeroderma pigmentosum complementation group C patients and functional study of XPC Q320X mutant.

    PubMed

    Gu, Yajuan; Chang, Xiaodan; Dai, Shan; Song, Qinghua; Zhao, Hongshan; Lei, Pengcheng

    2017-09-10

    Xeroderma pigmentosum (XP) is a rare, recessive hereditary disease characterized by sunlight hypersensitivity and high incidence of skin cancer with clinical and genetic heterogeneity. We collected two unrelated Chinese patients showing typical symptoms of XPC without neurologic symptoms. Direct sequencing of XPC gene revealed that patient 1 carried IVS1+1G>A and c.958 C>T mutations, and patient 2 carried c.545_546delTA and c.2257_2258insC mutations. All these four mutations introduced premature terminal codons (PTCs) in XPC gene. The nonsense mutation c.958 C>T yielded truncated mutant Q320X, and we studied its function for global genome repair kinetics. Overexpressed Q320X mutant can localize to site of DNA damage, but it is defective in CPD and 6-4PP repair. Readthrough of PTCs is a new approach to treatment of genetic diseases. We found that aminoglycosides could significantly increase the full length protein expression of Q320X mutant, but NER defects were not rescued in vitro. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. 34 CFR 106.71 - Procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....51 Job Classification and Structure, 106.55 Marital and Parental Status, 106.57 Pregnancy, [85, 93]; 106.57(b) Pregnancy as Temporary Disability, [85, 93]; 106.57(c) Pregnancy Leave, [85, 93, 94]; 106.57... Marital and Parental Status Employment General, [85, 93, 94]; 106.57 Pregnancy, [85, 93, 94]; 106.57(b...

  8. 34 CFR 106.71 - Procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....51 Job Classification and Structure, 106.55 Marital and Parental Status, 106.57 Pregnancy, [85, 93]; 106.57(b) Pregnancy as Temporary Disability, [85, 93]; 106.57(c) Pregnancy Leave, [85, 93, 94]; 106.57... Marital and Parental Status Employment General, [85, 93, 94]; 106.57 Pregnancy, [85, 93, 94]; 106.57(b...

  9. 34 CFR 106.71 - Procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....51 Job Classification and Structure, 106.55 Marital and Parental Status, 106.57 Pregnancy, [85, 93]; 106.57(b) Pregnancy as Temporary Disability, [85, 93]; 106.57(c) Pregnancy Leave, [85, 93, 94]; 106.57... Marital and Parental Status Employment General, [85, 93, 94]; 106.57 Pregnancy, [85, 93, 94]; 106.57(b...

  10. 32 CFR 320.11 - Penalties.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.11 Penalties. The Privacy Act of 1974 (5 U.S.C... similar penalties for violations by NGA employees of the Act or regulations established thereunder. ...

  11. 32 CFR 320.11 - Penalties.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.11 Penalties. The Privacy Act of 1974 (5 U.S.C... similar penalties for violations by NGA employees of the Act or regulations established thereunder. ...

  12. 46 CFR 308.550 - Certificate, Form MA-320.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Certificate, Form MA-320. 308.550 Section 308.550 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War... MA-320-C for a corporation, which forms may be obtained from the American War Risk Agency or MARAD. ...

  13. 46 CFR 308.550 - Certificate, Form MA-320.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Certificate, Form MA-320. 308.550 Section 308.550 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War... MA-320-C for a corporation, which forms may be obtained from the American War Risk Agency or MARAD. ...

  14. 46 CFR 308.550 - Certificate, Form MA-320.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false Certificate, Form MA-320. 308.550 Section 308.550 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War... MA-320-C for a corporation, which forms may be obtained from the American War Risk Agency or MARAD. ...

  15. 46 CFR 308.550 - Certificate, Form MA-320.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false Certificate, Form MA-320. 308.550 Section 308.550 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War... MA-320-C for a corporation, which forms may be obtained from the American War Risk Agency or MARAD. ...

  16. 32 CFR 320.12 - Exemptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.12 Exemptions. Link to an amendment published... NGA and its components shall be exempt from the requirements of 5 U.S.C. 552a(d) pursuant to 5 U.S.C... or prosecutable interest by the NGA or other agencies. This could seriously compromise case...

  17. Highly efficient production of L-lactic acid from xylose by newly isolated Bacillus coagulans C106.

    PubMed

    Ye, Lidan; Zhou, Xingding; Hudari, Mohammad Sufian Bin; Li, Zhi; Wu, Jin Chuan

    2013-03-01

    Cost-effective production of optically pure lactic acid from lignocellulose sugars is commercially attractive but challenging. Bacillus coagulans C106 was isolated from environment and used to produce l-lactic acid from xylose at 50°C and pH 6.0 in mineral salts medium containing 1-2% (w/v) of yeast extract without sterilizing the medium before fermentation. In batch fermentation with 85g/L of xylose, lactic acid titer and productivity reached 83.6g/L and 7.5g/Lh, respectively. When fed-batch (120+80+60g/L) fermentation was applied, they reached 215.7g/L and 4.0g/Lh, respectively. In both cases, the lactic acid yield and optical purity reached 95% and 99.6%, respectively. The lactic acid titer and productivity on xylose are the highest among those ever reported. Ca(OH)2 was found to be a better neutralizing agent than NaOH in terms of its giving higher lactic acid titer (1.2-fold) and productivity (1.8-fold) under the same conditions. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. 26 CFR 1.381(c)(24)-1 - Work incentive program credit carryovers in certain corporate acquisitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Work incentive program credit carryovers in... SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Insolvency Reorganizations § 1.381(c)(24)-1 Work incentive program credit carryovers in certain corporate acquisitions. The...

  19. Biosorption of americium-241 by immobilized Rhizopus arrihizus.

    PubMed

    Liao, Jiali; Yang, Yuanyou; Luo, Shunzhong; Liu, Ning; Jin, Jiannan; Zhang, Taiming; Zhao, Pengji

    2004-01-01

    Rhizopus arrihizus (R. arrihizus), a fungus, which in previous experiments had shown encouraging ability to remove 241Am from solutions, was immobilized by calcium alginate and other reagents. The various factors affecting 241Am biosorption by the immobilized R. arrihizus were investigated. The results showed that not only can immobilized R. arrihizus adsorb 241Am as efficiently as free R. arrihizus, but that also can be used repeatedly or continuously. The biosorption equilibrium was achieved within 2 h, and more than 94% of 241Am was removed from 241Am solutions of 1.08 MBq/l by immobilized R. arrihizu in the pH range 1-7. Temperature did not affect the adsorption on immobilized R. arrihizus in the range 15-45 degrees C. After repeated adsorption for 8 times, the immobilized R. arrihizus still adsorbed more than 97% of 241Am. At this time, the total adsorption of 241Am was more than 88.6 KBq/g, and had not yet reached saturation. Ninety-five percent of the adsorbed 241Am was desorbed by saturated EDTA solution and 98% by 2 mol/l HNO(3).

  20. Irradiation Microstructure of Austenitic Steels and Cast Steels Irradiated in the BOR-60 Reactor at 320°C

    NASA Astrophysics Data System (ADS)

    Yang, Yong; Chen, Yiren; Huang, Yina; Allen, Todd; Rao, Appajosula

    Reactor internal components are subjected to neutron irradiation in light water reactors, and with the aging of nuclear power plants around the world, irradiation-induced material degradations are of concern for reactor internals. Irradiation-induced defects resulting from displacement damage are critical for understanding degradation in structural materials. In the present work, microstructural changes due to irradiation in austenitic stainless steels and cast steels were characterized using transmission electron microscopy. The specimens were irradiated in the BOR-60 reactor, a fast breeder reactor, up to 40 dpa at 320°C. The dose rate was approximately 9.4x10-7 dpa/s. Void swelling and irradiation defects were analyzed for these specimens. A high density of faulted loops dominated the irradiated-altered microstructures. Along with previous TEM results, a dose dependence of the defect structure was established at 320°C.

  1. Chelation therapy of incorporated plutonium-238 and americium-241: comparison of LICAM(C), DTPA and DFOA in rats, hamsters and mice.

    PubMed

    Volf, V

    1986-03-01

    The carboxylated catechoylamide 3,4,3-LICAM(C) was tested for removal of 238Pu and 241Am from small laboratory rodents. The effectiveness of treatment was compared with that of two ligand preparations approved for clinical use: calcium-trisodium diethylenetriaminepentaacetate (DTPA) and desferrioxamine (DFOA). With early treatment and at the dosage used clinically for the decorporation of actinides with DTPA (30 mumol/kg body weight) LICAM(C) was superior to DFOA but when compared with DTPA, the effect of LICAM(C) on 238Pu was greater only in bone; as little as 1 mumol LICAM(C)/kg was as effective as 30 mumol DTPA/kg. However, in all animals treated with LICAM(C) there was a large increase in the 238Pu content of the kidney. With 241Am the effect of DTPA was always superior to that of LICAM(C). The best overall results early (1 day) after injection of 238Pu and 241Am were achieved by a combination of a single injection of LICAM(C) and DTPA with subsequent continuous administration of DTPA in drinking water. LICAM(C) affected the retention of 238Pu even if given orally; the data suggested that about 3 per cent of ingested LICAM(C) was absorbed. When the beginning of treatment was delayed, LICAM(C) became equally effective or less effective than DTPA even as far as 238Pu retention in bone was concerned, but it still increased the accumulation of 238Pu in the kidneys.

  2. Infrastructure and adaptive management in an eco-hydrological Delta: Lessons learned from design and construction of the Haringvliet Sluices

    NASA Astrophysics Data System (ADS)

    Linsen, Max; Mostert, Erik; van der Zaag, Pieter

    2015-04-01

    Consequences of climate change include an increase in extreme weather events in North-West Europe. The Netherlands is directly affected by these extreme events, in particular in water management practices. Large investments in infrastructure were made ever since the floods of 1953, leading to a higher level of protection against flooding from the sea and to a managed eco-hydrological Delta. Adaptive water management is presented as an approach to deal with challenges in water allocation and flood protection. One challenge to adaptive water management relates to infrastructure. Large works are often inevitable and essential in flood protection. Hydraulic infrastructure however tends to be inflexible by nature and requires a level of robustness to deliver the desired performance over time. In this study, we focus on the relation between desired performance of infrastructure and adaptation to environmental change and evolving social demands. The objective of this study is to gain an understanding of the evolution of the desired performance of water management infrastructure. This serves two purposes: an increased understanding of design and construction of existing infrastructure, and potential lessons learned for future hydraulic infrastructure in the context of adaptive management. A qualitative approach was used to evaluate over 130 reports on all stages of the design, planning and construction of the Haringvliet sluices as part of the realization of the Delta Works. The time frame is set between 1950 and 1970. The main source of information is a set of quarterly reports to the Dutch parliament, published between 1956 and 1988, and which provided detailed information on design, construction, maintenance, system behavior, policy needs, social demands and stakeholders. The original objectives of the infrastructure were reflected in its design: protection against flooding, protection against salt intrusion and discharge of water and ice - all with a desired ease of

  3. 320-nm Flexible Solution-Processed 2,7-dioctyl[1] benzothieno[3,2-b]benzothiophene Transistors

    PubMed Central

    Ren, Hang; Tang, Qingxin; Tong, Yanhong; Liu, Yichun

    2017-01-01

    Flexible organic thin-film transistors (OTFTs) have received extensive attention due to their outstanding advantages such as light weight, low cost, flexibility, large-area fabrication, and compatibility with solution-processed techniques. However, compared with a rigid substrate, it still remains a challenge to obtain good device performance by directly depositing solution-processed organic semiconductors onto an ultrathin plastic substrate. In this work, ultrathin flexible OTFTs are successfully fabricated based on spin-coated 2,7-dioctyl[1]benzothieno[3,2-b]benzothiophene (C8-BTBT) films. The resulting device thickness is only ~320 nm, so the device has the ability to adhere well to a three-dimension curved surface. The ultrathin C8-BTBT OTFTs exhibit a mobility as high as 4.36 cm2 V−1 s−1 and an on/off current ratio of over 106. These results indicate the substantial promise of our ultrathin flexible C8-BTBT OTFTs for next-generation flexible and conformal electronic devices. PMID:28792438

  4. 7 CFR 58.241 - Packaging, repackaging and storage.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Packaging, repackaging and storage. 58.241 Section 58... Service 1 Operations and Operating Procedures § 58.241 Packaging, repackaging and storage. (a) Containers... palleting or dry storage areas. (c) Repackaging. The entire repackaging operation shall be conducted in a...

  5. 7 CFR 58.241 - Packaging, repackaging and storage.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Packaging, repackaging and storage. 58.241 Section 58... Service 1 Operations and Operating Procedures § 58.241 Packaging, repackaging and storage. (a) Containers... palleting or dry storage areas. (c) Repackaging. The entire repackaging operation shall be conducted in a...

  6. Dimethylformamide as a cryoprotectant for canine semen diluted and frozen in ACP-106C.

    PubMed

    Mota Filho, A C; Teles, C H A; Jucá, R P; Cardoso, J F S; Uchoa, D C; Campello, C C; Silva, A R; Silva, L D M

    2011-10-15

    The objective was to assess the effect of adding various concentrations of dimethylformamide on characteristics of canine semen diluted in powdered coconut water (ACP-106C; ACP Biotecnologia, Fortaleza, CE, Brazil) and frozen at -196°C. Fifteen ejaculates were collected by manual stimulation from five adult Boxer dogs. The sperm-rich fraction was diluted in ACP-106C (ACP Biotecnologia) containing 10% egg yolk and divided into four aliquots. The cryoprotectants used for each aliquot were 6% glycerol (control group; CG) or 2%, 4%, or 6% dimethylformamide (DF2, DF4, and DF6, respectively). After thawing, total motility (mean ± SEM) for CG (58.4 ± 24.6) was higher (P < 0.05) than that of the other groups (2% dimethylformamide, 24.4 ± 12.3; 4% dimethylformamide, 26.5 ± 16.1; and 6% dimethylformamide, 21.7 ± 17.9). Furthermore, there was a greater percentage of fast, average, and slow moving sperm (assessed with computer-aided semen analysis; CASA) in CG in comparison with the other three groups. Therefore, based on concentrations tested in this study, dimethylformamide, together with ACP-106C (ACP Biotecnologia) and 10% egg yolk as a diluent, yielded unsatisfactory in vitro results for freezing canine semen. Copyright © 2011 Elsevier Inc. All rights reserved.

  7. Final Report of Tank 241-C-105 Dissolution, the Phase 2 Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meznarich, Huei K.; bolling, Stacey D.; Cooke, Gary A.

    2016-10-01

    Three clamshell grab samples were taken from Tank 241-C-105 in October 2015 in accordance with RPP-PLAN-60011. Analytical results of those samples were issued in the report RPP-RPT-59115 by Wastren Advantage, Inc., Hanford Laboratory. Solid phase characterization results were reported separately in LAB-RPT-15-00011 and in RPP-RPT-59147. The major solid phases reported to be present were dawsonite [NaAlCO 3(OH) 2], trona [Na 3(HCO 3)(CO 3)·2H 2O], cejkaite [Na 4(UO 2)(CO 3) 3], and an unidentified organic solid, with minor amounts of gibbsite [Al(OH) 3], natrophosphate [Na 7F(PO 4) 2·19H 2O], and traces of unidentified iron-rich and manganese-rich phases. Note that the presencemore » of dawsonite, trona, and cejkaite requires a relatively low pH, likely around pH 9 to 10. One aliquot of each grab sample was provided to 222-S Laboratory Process Chemistry for dissolution studies. Phase 1 of the dissolution testing followed the approved test plan, WRPS-1404813, Rev. 3, and examined the behavior of the Tank 241-C-105 solids treated with water, 19M sodium hydroxide, 2M nitric acid, and 0.5M oxalic acid/2M nitric acid. Phase 2 of the testing was conducted in accordance with instructions from the client and emphasized treatment with 19M sodium hydroxide followed by water washing. This is the report of the Phase 2 testing.« less

  8. Cystatin C Properties Crucial for Uptake and Inhibition of Intracellular Target Enzymes*

    PubMed Central

    Wallin, Hanna; Abrahamson, Magnus; Ekström, Ulf

    2013-01-01

    To elucidate the molecular requirements for cancer cell internalization of the extracellular cysteine protease inhibitor cystatin C, 12 variants of the protein were produced and used for uptake experiments in MCF-7 cells. Variants with alterations in the cysteine cathepsin binding region ((Δ1–10)-, K5A-, R8G-, (R8G,L9G,V10G)-, (R8G,L9G,V10G,W106G)-, and W106G-cystatin C) were internalized to a very low extent compared with the wild-type inhibitor. Substitutions of N39 in the legumain binding region (N39K- and N39A-cystatin C) decreased the internalization and (R24A,R25A)-cystatin C, with substitutions of charged residues not involved in enzyme inhibition, was not taken up at all. Two variants, W106F- and K75A-cystatin C, showed that the internalization can be positively affected by engineering of the cystatin molecule. Microscopy revealed vesicular co-localization of internalized cystatin C with the lysosomal marker proteins cathepsin D and legumain. Activities of both cysteine cathepsins and legumain, possible target enzymes associated with cancer cell invasion and metastasis, were down-regulated in cell homogenates following cystatin C uptake. A positive effect on regulation of intracellular enzyme activity by a cystatin variant selected from uptake properties was illustrated by incubating cells with W106F-cystatin C. This resulted in more efficient down-regulation of intracellular legumain activity than when cells were incubated with wild-type cystatin C. Uptake experiments in prostate cancer cells corroborated that the cystatin C internalization is generally relevant and confirmed an increased uptake of W106F-cystatin C, in PC3 cells. Thus, intracellular cysteine proteases involved in cancer-promoting processes might be controled by cystatin uptake. PMID:23629651

  9. Straightforward entry to pyrido[2,3-d]pyrimidine-2,4(1H,3H)-diones and their ADME properties.

    PubMed

    Jatczak, Martyna; Muylaert, Koen; De Coen, Laurens M; Keemink, Janneke; Wuyts, Benjamin; Augustijns, Patrick; Stevens, Christian V

    2014-08-01

    A straightforward synthesis of pyrido[2,3-d]pyrimidine-2,4(1H,3H)-diones was developed starting from 2-chloropyridine-3-carboxylic acid by esterification, nucleophilic aromatic substitution and amide formation in one step, and ring closure allowing their synthesis with two identical or two different group attached to nitrogen. The structural diversity of these [2,3-d]pyrimidine-2,4(1H,3H)-diones resulted in significant variation in the biopharmaceutical properties. This was reflected by the broad range in fasted state simulated intestinal fluid solubility values (12.6 μM to 13.8 mM), Caco-2 permeability coefficients (1.2 × 10(-6)cm/s to 90.7 × 10(-6)cm/s) and in vitro-predicted human in vivo intrinsic clearance values (0 to 159 ml/min/kg). Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. 10 CFR 32.102 - Schedule C-prototype tests for calibration or reference sources containing americium-241 or...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Schedule C-prototype tests for calibration or reference sources containing americium-241 or radium-226. 32.102 Section 32.102 Energy NUCLEAR REGULATORY COMMISSION SPECIFIC DOMESTIC LICENSES TO MANUFACTURE OR TRANSFER CERTAIN ITEMS CONTAINING BYPRODUCT MATERIAL Generally...

  11. CESIUM REMOVAL FROM TANKS 241-AN-103 & 241-SX-105 & 241-AZ-101 & 241AZ-102 COMPOSITE FOR TESTING IN BENCH SCALE STEAM REFORMER

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DUNCAN JB; HUBER HJ

    2011-04-21

    This report documents the preparation of three actual Hanford tank waste samples for shipment to the Savannah River National Laboratory (SRNL). Two of the samples were dissolved saltcakes from tank 241-AN-103 (hereafter AN-103) and tank 241-SX-105 (hereafter SX-105); one sample was a supernate composite from tanks 241-AZ-101 and 241-AZ-102 (hereafter AZ-101/102). The preparation of the samples was executed following the test plans LAB-PLAN-10-00006, Test Plan for the Preparation of Samples from Hanford Tanks 241-SX-105, 241-AN-103, 241-AN-107, and LAB-PLN-l0-00014, Test Plan for the Preparation of a Composite Sample from Hanford Tanks 241-AZ-101 and 241-AZ-102 for Steam Reformer Testing at the Savannahmore » River National Laboratory. All procedural steps were recorded in laboratory notebook HNF-N-274 3. Sample breakdown diagrams for AN-103 and SX-105 are presented in Appendix A. The tank samples were prepared in support of a series of treatability studies of the Fluidized Bed Steam Reforming (FBSR) process using a Bench-Scale Reformer (BSR) at SRNL. Tests with simulants have shown that the FBSR mineralized waste form is comparable to low-activity waste glass with respect to environmental durability (WSRC-STI-2008-00268, Mineralization of Radioactive Wastes by Fluidized Bed Steam Reforming (FBSR): Comparisons to Vitreous Waste Forms and Pertinent Durability Testing). However, a rigorous assessment requires long-term performance data from FBSR product formed from actual Hanford tank waste. Washington River Protection Solutions, LLC (WRPS) has initiated a Waste Form Qualification Program (WP-5.2.1-2010-001, Fluidized Bed Steam Reformer Low-level Waste Form Qualification) to gather the data required to demonstrate that an adequate FBSR mineralized waste form can be produced. The documentation of the selection process of the three tank samples has been separately reported in RPP-48824, Sample Selection Process for Bench-Scale Steam Reforming Treatability Studies

  12. 10. Historic American Buildings Survey W. N. Manning, Photographer, May ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Historic American Buildings Survey W. N. Manning, Photographer, May 18, 1935 TREATMENT OF DOUBLE DOOR FROM PARLOR TO SITTING ROOM, S. W. ROOM - Elmoreland, U.S. Highway 241, Glenville, Russell County, AL

  13. Commander Wilcutt works at the commander's workstation during STS-106

    NASA Image and Video Library

    2000-09-11

    STS106-352-009 (8-20 September 2000) --- Astronaut Terrence W. Wilcutt, STS-106 mission commander, performs a firing of the reaction control system on the flight deck of the Space Shuttle Atlantis. Earth’s horizon is visible through the commander’s window.

  14. Favoring the birth of female puppies after artificial insemination using chilled semen diluted with powdered coconut water (ACP-106c).

    PubMed

    Uchoa, Daniel Couto; da Silva, Ticiana Franco Pereira; Cardoso, Janaína de Fátima Saraiva; Mota Filho, Antônio Cavalcante; Jucá, Ricardo Parente; Silva, Alexandre Rodrigues; da Silva, Lúcia Daniel Machado

    2012-06-01

    The objective was to determine the effect of powdered coconut water extender (ACP-106c) on the proportion of female puppies born. Twenty French Bulldog bitches were subjected to natural mating (NM) and, during the subsequent two estrus periods, were bred by intravaginal artificial insemination (AI), using chilled semen (from the same males) diluted in Tris-egg yolk (AI-Tris) or ACP-106c (AI-ACP-106c). Fresh semen was cooled to 5 °C and maintained at that temperature for 6 h, rewarmed (37 °C for 30 s), and used for AI. Pregnancy and whelping rates following NM were both 100% and were both 90.0% following AI with either extender. Litter size (mean ± SD) was 5.4 ±1.1, 4.7 ± 2.0, and 5.1 ± 2.0 (P > 0.05) for NM, AI-Tris, and AI-ACP-106c, respectively. Furthermore, for these groups, the number of female vs. male puppies born were 2.6 ± 0.6 vs. 2.8 ± 1.0, 2.2 ± 1.0 vs. 2.5 ± 1.1, and 3.4 ± 1.6 vs. 1.8 ± 1.2 (P < 0.05 for AI-ACP-106c only). In conclusion, our hypothesis was supported; AI of semen in ACP-106c extender resulted in a significantly higher proportion of female puppies. Furthermore, this extender yielded acceptable litter size and rates of pregnancy and whelping. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. Distribution of C16:0, C18:0, C24:1, and C24:0 sulfatides in central nervous system lipid rafts by quantitative ultra-high-pressure liquid chromatography tandem mass spectrometry.

    PubMed

    Moyano, Ana Lis; Li, Guannan; Lopez-Rosas, Aurora; Månsson, Jan-Eric; van Breemen, Richard B; Givogri, Maria Irene

    2014-12-15

    Sulfated galactosylceramides (sulfatides) are glycosphingolipids associated with cholesterol- and sphingolipid-enriched membrane microdomains (lipid rafts) and are highly expressed in brain tissue. Although it is known that sulfatide species show heterogeneity in their fatty acid acyl group composition throughout brain development, their lipid raft distribution and biological relevance is poorly understood. We validated a fast and sensitive ultra-high-pressure liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method to measure developmentally regulated sulfatide species (C16:0, C18:0, C24:1, and C24:0) in central nervous system (CNS) lipid rafts isolated without using detergent. Our UHPLC-MS/MS assay showed good accuracy and precision with a linear range of 5 to 1,000 nM for C18:0 and C24:1 sulfatides and 10 to 1,000 nM for C16:0 and C24:0 sulfatides. We applied this quantitative analysis to detergent-free lipid rafts isolated from wild-type mice and arylsulfatase A-deficient (ASA knockout) mice that accumulate sulfatides. All four sulfatide species were more abundant in raft membranes than in non-raft membranes, with a significant increase in lipid rafts isolated from ASA knockout mice. This is the first description of an analytical method to study these sulfatide species in raft and non-raft membranes and has the potential to be applied to preparations from other tissues. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. Results of Characterization and Retrieval Testing on Tank 241-C-109 Heel Solids

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Callaway, William S.

    at temperatures ranging from 26-30 °C. The metathesized sodium aluminate was then dissolved by addition of volumes of water approximately equal to 1.3 times the volumes of caustic added to the test slurries. Aluminate dissolution was allowed to proceed for 2 days at ambient temperatures of ≈29 °C. Overall, the sequential water and caustic dissolution tests dissolved and removed 80.0 wt% of the tank 241-C-109 crushed heel solids composite test sample. The 20 wt% of solids remaining after the dissolution tests were 85-88 wt% gibbsite. If the density of the residual solids was approximately equal to that of gibbsite, they represented ≈17 vol% of the initial crushed solids composite test sample. In the water dissolution tests, addition of a volume of water ≈6.9 times the initial volume of the crushed solids composite was sufficient to dissolve and recover essentially all of the natrophosphate present. The ratio of the weight of water required to dissolve the natrophosphate solids to the estimated weight of natrophosphate present was 8.51. The Environmental Simulation Program (OLI Systems, Inc., Morris Plains, New Jersey) predicts that an 8.36 w/w ratio would be required to dissolve the estimated weight of natrophosphate present in the absence of other components of the heel solids. Only minor amounts of Al-bearing solids were removed from the composite solids in the water dissolution tests. The caustic metathesis/aluminate dissolution test sequence, executed at temperatures ranging from 27-30 °C, dissolved and recovered ≈69 wt% of the gibbsite estimated to have been present in the initial crushed heel solids composite. This level of gibbsite recovery is consistent with that measured in previous scoping tests on the dissolution of gibbsite in strong caustic solutions. Overall, the sequential water and caustic dissolution tests dissolved and removed 80.3 wt% of the tank 241-C-109 aggregate solids test sample. The residual solids were 92-95 wt% gibbsite. Only a

  17. STS-106 Crew Activities Report/Flight Day 04 Highlights

    NASA Technical Reports Server (NTRS)

    2000-01-01

    On this fourth day of the STS-106 Atlantis mission, the flight crew, Commander Commander Terrence W. Wilcutt, Pilot Scott D. Altman, and Mission Specialists Daniel C. Burbank, Edward T. Lu, Richard A. Mastracchio, Yuri Ivanovich Malenchenko, and Boris V. Morukov are seen preparing for the scheduled space walk. Lu and Malenchenko are seen coming through the hatch of the International Space Station (ISS). Also shown are Lu and Malenchenko attaching a magnetometer and boom to Zvezda. Mastracchio operates the robot arm moving the extravehicular activity (EVA) crew outside of the ISS.

  18. 46 CFR 178.320 - Intact stability requirements-non-sailing vessels.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Intact stability requirements-non-sailing vessels. 178.320 Section 178.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER... Intact stability requirements—non-sailing vessels. (a) As permitted by § 178.310(c) of this part, the...

  19. 39 CFR 320.4 - Suspension for certain letters of college and university organizations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... university organizations. 320.4 Section 320.4 Postal Service UNITED STATES POSTAL SERVICE RESTRICTIONS ON PRIVATE CARRIAGE OF LETTERS SUSPENSION OF THE PRIVATE EXPRESS STATUTES § 320.4 Suspension for certain letters of college and university organizations. The operation of 39 U.S.C. 601(a) (1) through (6) and...

  20. 39 CFR 320.4 - Suspension for certain letters of college and university organizations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... university organizations. 320.4 Section 320.4 Postal Service UNITED STATES POSTAL SERVICE RESTRICTIONS ON PRIVATE CARRIAGE OF LETTERS SUSPENSION OF THE PRIVATE EXPRESS STATUTES § 320.4 Suspension for certain letters of college and university organizations. The operation of 39 U.S.C. 601(a) (1) through (6) and...

  1. 39 CFR 320.4 - Suspension for certain letters of college and university organizations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... university organizations. 320.4 Section 320.4 Postal Service UNITED STATES POSTAL SERVICE RESTRICTIONS ON PRIVATE CARRIAGE OF LETTERS SUSPENSION OF THE PRIVATE EXPRESS STATUTES § 320.4 Suspension for certain letters of college and university organizations. The operation of 39 U.S.C. 601(a) (1) through (6) and...

  2. 39 CFR 320.4 - Suspension for certain letters of college and university organizations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... university organizations. 320.4 Section 320.4 Postal Service UNITED STATES POSTAL SERVICE RESTRICTIONS ON PRIVATE CARRIAGE OF LETTERS SUSPENSION OF THE PRIVATE EXPRESS STATUTES § 320.4 Suspension for certain letters of college and university organizations. The operation of 39 U.S.C. 601(a) (1) through (6) and...

  3. STS106-s-013

    NASA Image and Video Library

    2000-09-08

    STS106-S-013 (8 September 2000)--- This view of shock-wave condensation collars backlit by the Sun occurred during the launch of the Space Shuttle Atlantis on September 8, 2000. The scene was captured on 35mm motion picture film. One frame was digitized to make this still image. Although the primary effect is created by the forward fuselage of the Atlantis, secondary effects can be seen on the solid rocket booster (SRB) forward skirt, shuttle vertical stabilizer and wing trailing edge, behind the Space Shuttle Main Engines (SSME). The perfect on-time launch took place at 8:45:47 a.m. (EDT), September 8, 2000. Onboard the shuttle were astronauts Terrence W. Wilcutt, Scott D. Altman, Edward T. Lu, Richard A. Mastracchio and Daniel C. Burbank, along with cosmonauts Yuri I. Malenchenko and Boris V. Morukov who represent the Russian Aviation and Space Agency.

  4. HOW OLD IS IT? - 241PU/241AM NUCLEAR FORENSIC CHRONOLOGY REFERENCE MATERIALS

    PubMed Central

    Fitzgerald, Ryan; Inn, Kenneth G.W.; Horgan, Christopher

    2018-01-01

    One material attribute for nuclear forensics is material age. 241Pu is almost always present in uranium- and plutonium-based nuclear weapons, which pose the greatest threat to our security. The in-growth of 241Am due to the decay of 241Pu provides an excellent chronometer of the material. A well-characterized 241Pu/241Am standard is needed to validate measurement capability, as a basis for between-laboratory comparability, and as material for verifying laboratory performance. This effort verifies the certification of a 38 year old 241Pu Standard Reference Material (SRM4340) through alpha-gamma anticoincidence counting, and also establishes the separation date to two weeks of the documented date. PMID:29720779

  5. STS-106 crew water survival training

    NASA Image and Video Library

    2000-03-21

    JSC2000-02564 (21 March 2000) --- Astronaut Terrence W. (Terry) Wilcutt, STS-106 mission commander, talks with crew training staff members during a simulation of an emergency bailout exercise in the water of the Neutral Buoyancy Laboratory (NBL) near the Johnson Space Center (JSC).

  6. The pressure dependence of physical properties of (W2/3Ti1/3)3AlC2 and its counterpart W3AlC2 by first-principles calculations

    NASA Astrophysics Data System (ADS)

    Li, Yefei; Sun, Liang; Xing, Jiandong; Ma, Shengqiang; Zheng, Qiaoling; Liu, Yangzhen

    2017-12-01

    First-principles calculations based on density functional theory (DFT) were used to investigate the mechanical properties, elastic anisotropy, electronic structure, optical properties and thermodynamic properties of a new quaternary MAX phase (W2/3Ti1/3)3AlC2 and its counterpart W3AlC2 under hydrostatic pressure. The results indicate that the volumetric shrinkage of (W2/3Ti1/3)3AlC2 is faster than that of axial shrinkage under hydrostatic pressure. The stress-strain method and Voigt-Reuss-Hill approximation were used to calculate elastic constants and moduli, respectively. These compounds are mechanically stable under hydrostatic pressure. Moreover, the moduli of (W2/3Ti1/3)3AlC2 and W3AlC2 increase with an increase in pressure. The anisotropic indexes and surface constructions of bulk and Young’s moduli were used to illustrate the mechanical anisotropy under hydrostatic pressure. Electronic structure and optical property of (W2/3Ti1/3)3AlC2 and W3AlC2 have also been discussed. The results of Debye temperature reveal that the covalent bonds among atoms in (W2/3Ti1/3)3AlC2 may be stronger than that of W3AlC2. The heat capacity, Cp-Cv, and thermal expansion coefficient of (W2/3Ti1/3)3AlC2 and W3AlC2 were discussed in the ranges of 0-30 GPa and 0-2000 K using quasi-harmonic Debye model considering the phonon effects.

  7. Direct-access retrieval during sentence comprehension: Evidence from Sluicing

    PubMed Central

    Martin, Andrea E.; McElree, Brian

    2011-01-01

    Language comprehension requires recovering meaning from linguistic form, even when the mapping between the two is indirect. A canonical example is ellipsis, the omission of information that is subsequently understood without being overtly pronounced. Comprehension of ellipsis requires retrieval of an antecedent from memory, without prior prediction, a property which enables the study of retrieval in situ (Martin & McElree, 2008, 2009). Sluicing, or inflectional phrase ellipsis, in the presence of a conjunction, presents a test case where a competing antecedent position is syntactically licensed, in contrast with most cases of nonadjacent dependency, including verb phrase ellipsis. We present speed-accuracy tradeoff and eye-movement data inconsistent with the hypothesis that retrieval is accomplished via a syntactically guided search, a particular variant of search not examined in past research. The observed timecourse profiles are consistent with the hypothesis that antecedents are retrieved via a cue-dependent direct-access mechanism susceptible to general memory variables. PMID:21580797

  8. Stabilization of Giant Fullerenes C2(41)-C90, D3(85)-C92, C1(132)-C94, C2(157)-C96, and C1(175)-C98 by Encapsulation of a Large La2C2 Cluster: The Importance of Cluster-Cage Matching.

    PubMed

    Zhao, Shasha; Zhao, Pei; Cai, Wenting; Bao, Lipiao; Chen, Muqing; Xie, Yunpeng; Zhao, Xiang; Lu, Xing

    2017-04-05

    Successful isolation and unambiguous crystallographic assignment of a series of higher carbide cluster metallofullerenes present new insights into the molecular structures and cluster-cage interactions of endohedral metallofullerenes. These new species are identified as La 2 C 2 @C 2 (41)-C 90 , La 2 C 2 @D 3 (85)-C 92 , La 2 C 2 @C 1 (132)-C 94 , La 2 C 2 @C 2 (157)-C 96 , and La 2 C 2 @C 1 (175)-C 98 . This is the first report for these new cage structures except for D 3 (85)-C 92 . Our experimental and theoretical results demonstrate that La 2 C 92-106 are more inclined to exist stably in the carbide form La 2 C 2 @C 90-104 rather than as the dimetallofullerenes La 2 @C 92-106 , which are rationalized by considering a synergistic effect of inserting a C 2 unit into the cage, which ensures strong metal-cage interactions by partially neutralizing the charges from the metal ions and by fulfilling the coordination requirement of the La 3+ ions as much as possible.

  9. Effect of americium-241 on luminous bacteria. Role of peroxides.

    PubMed

    Alexandrova, M; Rozhko, T; Vydryakova, G; Kudryasheva, N

    2011-04-01

    The effect of americium-241 ((241)Am), an alpha-emitting radionuclide of high specific activity, on luminous bacteria Photobacterium phosphoreum was studied. Traces of (241)Am in nutrient media (0.16-6.67 kBq/L) suppressed the growth of bacteria, but enhanced luminescence intensity and quantum yield at room temperature. Lower temperature (4 °C) increased the time of bacterial luminescence and revealed a stage of bioluminescence inhibition after 150 h of bioluminescence registration start. The role of conditions of exposure the bacterial cells to the (241)Am is discussed. The effect of (241)Am on luminous bacteria was attributed to peroxide compounds generated in water solutions as secondary products of radioactive decay. Increase of peroxide concentration in (241)Am solutions was demonstrated; and the similarity of (241)Am and hydrogen peroxide effects on bacterial luminescence was revealed. The study provides a scientific basis for elaboration of bioluminescence-based assay to monitor radiotoxicity of alpha-emitting radionuclides in aquatic solutions. Copyright © 2011 Elsevier Ltd. All rights reserved.

  10. 32 CFR 241.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.2 Definitions. In this... organizational goals. Information technology (IT) as defined in section 11101 of title 40, U.S.C. includes computers, ancillary equipment (including imaging peripherals, input, output, and storage devices necessary...

  11. 32 CFR 241.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL (EFF. UNTIL 7-20-2012) § 241.2... achieving the organizational goals. Information technology (IT) as defined in section 11101 of title 40, U.S.C. includes computers, ancillary equipment (including imaging peripherals, input, output, and...

  12. Theoretical predictions of properties and gas-phase chromatography behaviour of carbonyl complexes of group-6 elements Cr, Mo, W, and element 106, Sg.

    PubMed

    Pershina, V; Anton, J

    2013-05-07

    Fully relativistic, four-component density functional theory electronic structure calculations were performed for M(CO)6 of group-6 elements Cr, Mo, W, and element 106, Sg, with an aim to predict their adsorption behaviour in the gas-phase chromatography experiments. It was shown that seaborgium hexacarbonyl has a longer M-CO bond, smaller ionization potential, and larger polarizability than the other group-6 molecules. This is explained by the increasing relativistic expansion and destabilization of the (n - 1)d AOs with increasing Z in the group. Using results of the calculations, adsorption enthalpies of the group-6 hexacarbonyls on a quartz surface were predicted via a model of physisorption. According to the results, -ΔHads should decrease from Mo to W, while it should be almost equal--within the experimental error bars--for W and Sg. Thus, we expect that in the future gas-phase chromatography experiments it will be almost impossible--what concerns ΔHads--to distinguish between the W and Sg hexacarbonyls by their deposition on quartz.

  13. RMP effects on the W and C erosion/deposition balance on W test samples in DIII-D

    NASA Astrophysics Data System (ADS)

    Hinson, E. T.; Frerichs, H.; Schmitz, O.; Evans, T. E.; Guo, H. Y.; Thomas, D. M.; Rudakov, D. L.; Abrams, T.; Unterberg, E. A.; Briesemeister, A.; Lasnier, C. J.; McLean, A. G.; Makowski, M.; Wampler, W. R.; Watkins, J. G.; Wang, H. Q.

    2016-10-01

    Clear evidence for alteration of the W and C erosion by resonant magnetic perturbation (RMP) fields has been obtained in an experiment exposing W-coated DiMES samples in the DIII-D divertor to outer strike point (OSP) sweeps in comparable series of discharges with and without the application of RMP. Gross erosion measurements of W and C during these sweeps using the S/XB method show that the 3-D boundary induced by the RMP significantly alters the erosion rate from DiMES. In particular, application of RMP smooths radial W erosion anisotropy seen for the axisymmetric case, where the W erosion rate for the OSP sweep in the outward direction significantly exceeds the erosion rate observed for the subsequent inward radial sweep over the sample. This finding is likely related to a change in the W/C erosion and redeposition balance in the C-dominated wall environment at DIII-D. Moreover, non-axisymmetric plasma structure on the W sample has to be considered. This challenge will be further examined by comparison of experimental results to EMC3-EIRENE modeling. Work supported by US DOE DE-SC0013911, DE-FC02-04ER54698, DE-FH02-07ER54917, DE-AC05-06OR23100, DE-AC05-00OR22725, DE-AC52-07NA27344, and DE-AC04-94AL85000.

  14. STS-106 Crew Activities Report/Flight Day 9 Highlights

    NASA Technical Reports Server (NTRS)

    2000-01-01

    On this ninth day of the STS-106 Atlantis mission, the flight crew, Commander Commander Terrence W. Wilcutt, Pilot Scott D. Altman, and Mission Specialists Daniel C. Burbank, Edward T. Lu, Richard A. Mastracchio, Yuri Ivanovich Malenchenko, and Boris V. Morukov are shown transferring supplies and equipment. Equipment includes an exercise treadmill, for use by the first resident crew. Altman, Lu, Burbank and Morukov are seen installing the treadmill in the Zvezda module. Footage also shows Lu and Altman participating in a telecommunication interview. A beautiful night shot of the International Space Station (ISS) and Atlantis complex above the Earth is also shown.

  15. 24 CFR 241.1005 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...; § 241.1(k)—Energy conserving improvements; § 241.1(1)—Solar energy system. (b) As used in subpart E of...-Eligibility Requirements § 241.1005 Definitions. (a) All of the definitions of § 241.1 apply to equity and...

  16. Probing anomalous W W γ triple gauge bosons coupling at the LHeC

    NASA Astrophysics Data System (ADS)

    Li, Ruibo; Shen, Xiao-Min; Wang, Kai; Xu, Tao; Zhang, Liangliang; Zhu, Guohuai

    2018-04-01

    The precision measurement of the W W γ vertex at the future Large Hadron electron Collider (LHeC) at CERN is discussed in this paper. We propose to measure this vertex in the e-p →e-W±j channel as a complement to the conventional charged current νeγ j channel. In addition to the cross section measurement, χ2 method studies of angular variables provide powerful tools to probe the anomalous structure of triple gauge boson couplings. We study the distribution of the well-known azimuthal angle between the final state forward electron and jet in this vector-boson fusion process. On the other hand, full reconstruction of leptonic W decay opens a new opportunity to measure W polarization that is also sensitive to the anomalous triple gauge boson couplings. Taking into consideration the superior determination of parton distribution functions based on future LHeC data, the constraints of λγ and Δ κγ might reach up to O (10-3) level in the most ideal case with the 2 - 3 ab-1 data set, which shows a potential advantage compared to those from LHC and Large Electron-Positron Collider (LEP) data.

  17. An inversion of the estuarine circulation by sluice water discharge and its impact on suspended sediment transport

    NASA Astrophysics Data System (ADS)

    Schulz, Kirstin; Gerkema, Theo

    2018-01-01

    The Wadden Sea is characterized by a complex topography of branching channels and intertidal flats, in which the interplay between fresh water discharges, wind forcing and the tidal current causes sediment transport rates and direction to be highly variable in space and time. During three field campaigns, indications of a negative estuarine circulation have been found in a channel adjacent to the coast in the Western Dutch Wadden Sea. Contrary to the classical picture of estuarine circulation, a periodic density stratification was observed that builds up during flood and breaks down during ebb. This can be related to a large freshwater source at the mouth of the channel, the sluice in Kornwerderzand. In this study, observations of this phenomenon are presented, and with the help of a numerical model the different drivers for residual suspended matter transport in this area, namely tidal asymmetries in the current velocity and the above mentioned periodic stratification, are investigated. It is found that the residual current in the area of interest points in ebb direction, caused by both the elongated ebb flow phase and the periodic stratification. On the contrary, the stronger flood currents cause a transport of suspended matter in flood direction. This transport is counteracted and therefore diminished by the effects of the sluice discharge.

  18. STS-106 crew water survival training

    NASA Image and Video Library

    2000-03-21

    JSC2000-02567 (21 March 2000) --- Astronaut Terrence W. (Terry) Wilcutt, STS-106 mission commander, empties water from his newly-deployed life raft during a simulation of an emergency bailout exercise. The water survival training routinely takes place in the Neutral Buoyancy Laboratory (NBL) near the Johnson Space Center (JSC).

  19. β1-C121W Is Down But Not Out: Epilepsy-Associated Scn1b-C121W Results in a Deleterious Gain-of-Function

    PubMed Central

    Kruger, Larisa C.; O'Malley, Heather A.; Hull, Jacob M.; Kleeman, Amanda; Patino, Gustavo A.

    2016-01-01

    Voltage-gated sodium channel (VGSC) β subunits signal through multiple pathways on multiple time scales. In addition to modulating sodium and potassium currents, β subunits play nonconducting roles as cell adhesion molecules, which allow them to function in cell–cell communication, neuronal migration, neurite outgrowth, neuronal pathfinding, and axonal fasciculation. Mutations in SCN1B, encoding VGSC β1 and β1B, are associated with epilepsy. Autosomal-dominant SCN1B-C121W, the first epilepsy-associated VGSC mutation identified, results in genetic epilepsy with febrile seizures plus (GEFS+). This mutation has been shown to disrupt both the sodium-current-modulatory and cell-adhesive functions of β1 subunits expressed in heterologous systems. The goal of this study was to compare mice heterozygous for Scn1b-C121W (Scn1b+/W) with mice heterozygous for the Scn1b-null allele (Scn1b+/−) to determine whether the C121W mutation results in loss-of-function in vivo. We found that Scn1b+/W mice were more susceptible than Scn1b+/− and Scn1b+/+ mice to hyperthermia-induced convulsions, a model of pediatric febrile seizures. β1-C121W subunits are expressed at the neuronal cell surface in vivo. However, despite this, β1-C121W polypeptides are incompletely glycosylated and do not associate with VGSC α subunits in the brain. β1-C121W subcellular localization is restricted to neuronal cell bodies and is not detected at axon initial segments in the cortex or cerebellum or at optic nerve nodes of Ranvier of Scn1bW/W mice. These data, together with our previous results showing that β1-C121W cannot participate in trans-homophilic cell adhesion, lead to the hypothesis that SCN1B-C121W confers a deleterious gain-of-function in human GEFS+ patients. SIGNIFICANCE STATEMENT The mechanisms underlying genetic epilepsy syndromes are poorly understood. Closing this gap in knowledge is essential to the development of new medicines to treat epilepsy. We have used mouse models to

  20. 24 CFR 320.17 - Fees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Fees. 320.17 Section 320.17 Housing... SECURITIES Pass-Through Type Securities § 320.17 Fees. The Association may impose application fees, guaranty fees, securities transfer fees and other fees. ...

  1. 29 CFR 99.320 - Report submission.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... audit shall be completed and the data collection form and reporting package shall be submitted within....320 Report submission. (a) General. The audit shall be completed and the data collection form described in paragraph (b) of this section and reporting package described in paragraph (c) of this section...

  2. 29 CFR 99.320 - Report submission.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... audit shall be completed and the data collection form and reporting package shall be submitted within....320 Report submission. (a) General. The audit shall be completed and the data collection form described in paragraph (b) of this section and reporting package described in paragraph (c) of this section...

  3. 29 CFR 99.320 - Report submission.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... audit shall be completed and the data collection form and reporting package shall be submitted within....320 Report submission. (a) General. The audit shall be completed and the data collection form described in paragraph (b) of this section and reporting package described in paragraph (c) of this section...

  4. 36 CFR 241.21 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Conservation of Fish, Wildlife, and Their Habitat, Chugach National Forest, Alaska § 241.21 Definitions. For... refers to the Alaska National Interest Lands Conservation Act (16 U.S.C. 3101 et seq.) Federal lands mean... to a Native corporation or person. Fish and Wildlife means any member of the animal kingdom...

  5. 36 CFR 241.21 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Conservation of Fish, Wildlife, and Their Habitat, Chugach National Forest, Alaska § 241.21 Definitions. For... refers to the Alaska National Interest Lands Conservation Act (16 U.S.C. 3101 et seq.) Federal lands mean... to a Native corporation or person. Fish and Wildlife means any member of the animal kingdom...

  6. 36 CFR 241.21 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Conservation of Fish, Wildlife, and Their Habitat, Chugach National Forest, Alaska § 241.21 Definitions. For... refers to the Alaska National Interest Lands Conservation Act (16 U.S.C. 3101 et seq.) Federal lands mean... to a Native corporation or person. Fish and Wildlife means any member of the animal kingdom...

  7. 36 CFR 241.21 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Conservation of Fish, Wildlife, and Their Habitat, Chugach National Forest, Alaska § 241.21 Definitions. For... refers to the Alaska National Interest Lands Conservation Act (16 U.S.C. 3101 et seq.) Federal lands mean... to a Native corporation or person. Fish and Wildlife means any member of the animal kingdom...

  8. 36 CFR 241.21 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Conservation of Fish, Wildlife, and Their Habitat, Chugach National Forest, Alaska § 241.21 Definitions. For... refers to the Alaska National Interest Lands Conservation Act (16 U.S.C. 3101 et seq.) Federal lands mean... to a Native corporation or person. Fish and Wildlife means any member of the animal kingdom...

  9. STS-106 crew gathers to greet family members

    NASA Technical Reports Server (NTRS)

    2000-01-01

    While meeting with family on the day before launch, the STS-106 crew poses for a photo. Waving, left to right, are Mission Specialist Richard A. Mastracchio, Commander Terrence W. Wilcutt, Pilot Scott D. Altman, and Mission Specialists Edward T. Lu, Yuri I. Malenchenko, Boris V. Morukov and Daniel C. Burbank. Malenchenko and Morukov are with the Russian Aviation and Space Agency. In the background (left) is Launch Pad 39B and Space Shuttle Atlantis, with the Rotating Service Structure still in place. STS-106 is scheduled to launch Sept. 8, 2000, at 8:45 a.m. EDT from Launch Pad 39B. On the 11-day mission, the seven-member crew will perform support tasks on orbit, transfer supplies and prepare the living quarters in the newly arrived Zvezda Service Module. The first long-duration crew, dubbed '''Expedition One,''' is due to arrive at the Station in late fall. Landing is targeted for Sept. 19 at 4:59 a.m. EDT at the KSC Shuttle Landing Facility.

  10. Radioactive air emissions notice of construction for installation and operation of a waste retrieval system and tanks 241-AP-102 and 241-AP-104 project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DEXTER, M.L.

    1999-11-15

    This document serves as a notice of construction (NOC) pursuant to the requirements of Washington Administrative Code (WAC) 246 247-060, and as a request for approval to modify pursuant to 40 Code of Federal Regulations (CFR) 61 07 for the installation and operation of one waste retrieval system in the 24 1 AP-102 Tank and one waste retrieval system in the 241 AP 104 Tank Pursuant to 40 CFR 61 09 (a)( 1) this application is also intended to provide anticipated initial start up notification Its is requested that EPA approval of this application will also constitute EPA acceptance ofmore » the initial start up notification Project W 211 Initial Tank Retrieval Systems (ITRS) is scoped to install a waste retrieval system in the following double-shell tanks 241-AP 102-AP 104 AN 102, AN 103, AN-104, AN 105, AY 102 AZ 102 and SY-102 between now and the year 2011. Because of the extended installation schedules and unknowns about specific activities/designs at each tank, it was decided to submit NOCs as that information became available This NOC covers the installation and operation of a waste retrieval system in tanks 241 AP-102 and 241 AP 104 Generally this includes removal of existing equipment installation of new equipment and construction of new ancillary equipment and buildings Tanks 241 AP 102 and 241 AP 104 will provide waste feed for immobilization into a low activity waste (LAW) product (i.e. glass logs) The total effective dose equivalent (TEDE) to the offsite maximally exposed individual (MEI) from the construction activities is 0 045 millirem per year The unabated TEDE to the offsite ME1 from operation of the mixer pumps is 0 042 millirem per year.« less

  11. 27 CFR 21.106 - Diethyl phthalate.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Diethyl phthalate. 21.106....106 Diethyl phthalate. (a) Refractive index at 25 °C. 1.497 to 1.502. (b) Color. Colorless. (c) Odor... °/25 °C. 1.115 to 1.118. (f) Ester content (as diethyl phthalate). Not less than 99 percent by weight...

  12. 27 CFR 21.106 - Diethyl phthalate.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Diethyl phthalate. 21.106....106 Diethyl phthalate. (a) Refractive index at 25 °C. 1.497 to 1.502. (b) Color. Colorless. (c) Odor... °/25 °C. 1.115 to 1.118. (f) Ester content (as diethyl phthalate). Not less than 99 percent by weight...

  13. 27 CFR 21.106 - Diethyl phthalate.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Diethyl phthalate. 21.106....106 Diethyl phthalate. (a) Refractive index at 25 °C. 1.497 to 1.502. (b) Color. Colorless. (c) Odor... °/25 °C. 1.115 to 1.118. (f) Ester content (as diethyl phthalate). Not less than 99 percent by weight...

  14. 27 CFR 21.106 - Diethyl phthalate.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Diethyl phthalate. 21.106....106 Diethyl phthalate. (a) Refractive index at 25 °C. 1.497 to 1.502. (b) Color. Colorless. (c) Odor... °/25 °C. 1.115 to 1.118. (f) Ester content (as diethyl phthalate). Not less than 99 percent by weight...

  15. Lithium doping on covalent organic framework-320 for enhancing hydrogen storage at ambient temperature

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xia, Liangzhi, E-mail: 15004110853@163.com; Liu, Qing

    2016-12-15

    Density Functional Theory (DFT) combines with grand canonical Monte Carlo (GCMC) simulations are performed to explore the effect of Li doping on the hydrogen storage capability of COF-320. The results show that the interaction energy between the H{sub 2} and the Li-doped COF-320 is about three times higher than that of pristine COF-320. GCMC simulations are employed to study the hydrogen uptake of Li-doped COF-320 at ambient temperature, further confirm that the lithium doping can improve the hydrogen uptake at ambient temperature. Our results demonstrate that Li-doped COFs have good potential in the field of hydrogen storage. - Graphical abstract:more » Fig. 1. The optimized cluster model used here to represent the COF-320 and possible adsorption sites (A, B, C) for adsorption of metals in the COF-320. The dangling bonds are terminated by H atoms. C, H, and N atoms are shown as gray, white, and blue colors, respectively. Fig. 2. The adsorption isotherm of H{sub 2} in the pristine and Li-doped COF-320 at 298 K. - Highlights: • The binding sites of single and two lithium atoms in COF-320 were studied. • The interaction energy between the H{sub 2} and the Li-doped COF-320 is about three times higher than that of pristine COF-320. • H{sub 2} uptakes on the Li-doped COFs obtain significant improvement at ambient temperature. • Lithium-doping is a successful strategy for improving hydrogen uptake.« less

  16. Association of aldose reductase gene polymorphism (C-106T) in susceptibility of diabetic peripheral neuropathy among north Indian population.

    PubMed

    Gupta, Balram; Singh, S K

    2017-07-01

    Polymorphism in aldose reductase (ALR) gene at nucleotide C(-106)T (rs759853) in the promoter region is associated with susceptibility to development of diabetic peripheral neuropathy. The aim of this study was to detect the association of the C (-106)T polymorphism of ALR gene and its frequency among patients with type 2 diabetes mellitus with and without peripheral neuropathy. The study subjects were divided into three groups. Group I included 356 patients with diabetes having peripheral neuropathy. Group II included 294 patients with diabetes without peripheral neuropathy and group III included 181 healthy subjects. Genotyping of ALR C(-106)T SNPs was performed using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and direct sequencing methods. The genetic risk among the groups was compared and tested by calculating odds ratio with 95% class interval. ALR 106TT genotype was significantly higher in group I compared to group II with an odds ratio of 2.12 (95% CI: 1.22-3.67; p<0.01). Recessive model (CC+CT vs. TT), as well as T allele distribution also showed significant association to develop neuropathy with relative risk of 1.97 (95% CI: 1.16-3.35; p<0.01) and 1.36 (95% CI: 1.07-1.72; p=0.01) respectively. In conclusion, the ALR C-106T polymorphism was associated with higher risk of peripheral neuropathy in patients with type 2 diabetes mellitus. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Intravaginal artificial insemination in bitches using frozen/thawed semen after dilution in powdered coconut water (ACP-106c).

    PubMed

    Uchoa, D C; Silva, T F P; Mota Filho, A C; Silva, L D M

    2012-12-01

    The aim of this study was to evaluate powdered coconut water extender (ACP-106c; ACP Serviços Tecnológicos Ltda, ACP Biotecnologia, Fortaleza, Ceará, Brazil) as a diluent for freezing dog semen and the fertility after vaginal insemination of semen frozen therein. Ten ejaculates were collected from five dogs, evaluated fresh, diluted in ACP-106c, 10% egg yolk and 6% glycerol, cooled and frozen. In the first phase of the study, straws with frozen semen were thawed and immediately subjected to the same analysis as the fresh semen and, in addition, to Computer-Assisted Semen Analysis (CASA). In phase 2, 10 bitches that had been subjected to natural breeding during a preceding oestrous cycle were vaginally inseminated with thawed semen that had been re-diluted in ACP-106c. After thawing, a mean of 77% sperm motility was obtained through subjective analysis and 77.3% through CASA. Following artificial insemination, a 60% pregnancy rate was observed, resulting in a 50% parturition rate and a mean litter size of 3.4 (SEM 0.6), with 47.1% males and 52.9% females. ACP-106c can be successfully used for freezing canine semen, and vaginal deposition of such semen yields similar pregnancy rates to those reported in other studies. © 2012 Blackwell Verlag GmbH.

  18. 32 CFR 320.3 - Responsibilities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Responsibilities. 320.3 Section 320.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.3 Responsibilities. (a) Director of NGA: (1...

  19. 32 CFR 320.3 - Responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Responsibilities. 320.3 Section 320.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.3 Responsibilities. (a) Director of NGA: (1...

  20. 32 CFR 320.12 - Exemptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Exemptions. 320.12 Section 320.12 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.12 Exemptions. (a) Exempt systems of record...

  1. 32 CFR 320.3 - Responsibilities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Responsibilities. 320.3 Section 320.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.3 Responsibilities. (a) Director of NGA: (1...

  2. 32 CFR 320.12 - Exemptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Exemptions. 320.12 Section 320.12 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.12 Exemptions. (a) Exempt systems of record...

  3. 30 CFR 241.76 - Can MMS reduce my penalty once it is assessed?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Can MMS reduce my penalty once it is assessed? 241.76 Section 241.76 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Provisions § 241.76 Can MMS reduce my penalty once it is assessed? Under 30 U.S.C. 1719(g), the Director or...

  4. 24 CFR 990.320 - Audits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Audits. 990.320 Section 990.320... HOUSING OPERATING FUND PROGRAM Financial Management Systems, Monitoring, and Reporting § 990.320 Audits. All PHAs that receive financial assistance under this part shall submit an acceptable audit and comply...

  5. 32 CFR 320.10 - Fees.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Fees. 320.10 Section 320.10 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.10 Fees. Individuals may request copies for retention of...

  6. 32 CFR 320.10 - Fees.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Fees. 320.10 Section 320.10 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.10 Fees. Individuals may request copies for retention of...

  7. 32 CFR 320.10 - Fees.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Fees. 320.10 Section 320.10 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.10 Fees. Individuals may request copies for retention of...

  8. 32 CFR 320.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Definitions. 320.2 Section 320.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.2 Definitions. As used in this part: (a...

  9. 32 CFR 320.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Definitions. 320.2 Section 320.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.2 Definitions. As used in this part: (a...

  10. 24 CFR 320.5 - Securities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Securities. 320.5 Section 320.5... SECURITIES Pass-Through Type Securities § 320.5 Securities. (a) Instruments. Securities issued pursuant to the provisions of this subpart must be modified pass-through securities, that provide for payment...

  11. 24 CFR 320.5 - Securities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Securities. 320.5 Section 320.5... SECURITIES Pass-Through Type Securities § 320.5 Securities. (a) Instruments. Securities issued pursuant to the provisions of this subpart must be modified pass-through securities, that provide for payment...

  12. 24 CFR 320.5 - Securities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Securities. 320.5 Section 320.5... SECURITIES Pass-Through Type Securities § 320.5 Securities. (a) Instruments. Securities issued pursuant to the provisions of this subpart must be modified pass-through securities, that provide for payment...

  13. 24 CFR 320.5 - Securities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Securities. 320.5 Section 320.5... SECURITIES Pass-Through Type Securities § 320.5 Securities. (a) Instruments. Securities issued pursuant to the provisions of this subpart must be modified pass-through securities, that provide for payment...

  14. 24 CFR 320.33 - Fees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Fees. 320.33 Section 320.33 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT... SECURITIES Bond-Type Securities § 320.33 Fees. The Association may impose application and guaranty fees...

  15. 21 CFR 556.320 - Hydrocortisone.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Hydrocortisone. 556.320 Section 556.320 Food and... Residues of New Animal Drugs § 556.320 Hydrocortisone. A tolerance is established for negligible residues of hydrocortisone (as hydrocortisone sodium succinate or hydrocortisone acetate) in milk at 10 parts...

  16. 20 CFR 320.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Definitions. 320.2 Section 320.2 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT INITIAL... § 320.2 Definitions. As used in this part— Base-year employer means the railroad employer(s) for whom a...

  17. The efficacies of pure LICAM(C) and DTPA on the retention of plutonium-238 and americium-241 in rats after their inhalation as nitrate and intravenous injection as citrate.

    PubMed

    Stradling, G N; Stather, J W; Gray, S A; Moody, J C; Ellender, M; Hodgson, A; Volf, V; Taylor, D M; Wirth, P; Gaskin, P W

    1989-10-01

    The pure carboxylated catechoyl amide LICAM(C) and the calcium and zinc salts of diethylenetriaminepenta-acetic acid (DTPA), were tested for efficacy for removing 238Pu and 241Am from rats after inhalation of the nitrate or intravenous injection of the citrate. The results were compared with the efficacy of methylated LICAM(C) used in previous experiments. It was shown that: (1) after inhalation of 238Pu nitrate, DTPA was far superior to pure LICAM(C); (2) after intravenous injection of 238Pu citrate, the infusion of DTPA plus LICAM(C) was only marginally more effective than DTPA alone; and (3) after inhalation or intravenous injection of 238Pu plus 241Am, the efficacy of pure LICAM(C) was only marginally more effective than the methylated form and neither form was effective for the decorporation of 241Am. It was concluded that DTPA, at present, remains the chelating agent of choice for treating persons accidentally contaminated with transportable forms of Pu and Am.

  18. 24 CFR 14.320 - Settlement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Settlement. 14.320 Section 14.320... Applications § 14.320 Settlement. The applicant and agency counsel may agree on a proposed settlement of the award before final action on the application, either in connection with a settlement of the underlying...

  19. Looking north through the C.W.E. Storage Shed (Bldg. 126) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Looking north through the C.W.E. Storage Shed (Bldg. 126) - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, C.W.E. Storage Shed, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  20. C-2W Magnetic Measurement Suite

    NASA Astrophysics Data System (ADS)

    Roche, T.; Thompson, M. C.; Griswold, M.; Knapp, K.; Koop, B.; Ottaviano, A.; Tobin, M.; TAE, Tri Alpha Energy, Inc. Team

    2017-10-01

    Commissioning and early operations are underway on C-2W, Tri Alpha Energy's new FRC experiment. The increased complexity level of this machine requires an equally enhanced diagnostic capability. A fundamental component of any magnetically confined fusion experiment is a firm understanding of the magnetic field itself. C-2W is outfitted with over 700 magnetic field probes, 550 internal and 150 external. Innovative in-vacuum annular flux loop / B-dot combination probes will provide information about plasma shape, size, pressure, energy, total temperature, and trapped flux when coupled with establish theoretical interpretations. The massive Mirnov array, consisting of eight rings of eight 3D probes, will provide detailed information about plasma motion, stability, and MHD modal content with the aid of singular value decomposition (SVD) analysis. Internal Rogowski probes will detect the presence of axial currents flowing in the plasma jet in multiple axial locations. Initial data from this array of diagnostics will be presented along with some interpretation and discussion of the analysis techniques used.

  1. Spitzer c2d Legacy, Circumstellar Disks around wTT Stars

    NASA Astrophysics Data System (ADS)

    Wahhaj, Zahed; c2d Legacy Team

    2007-05-01

    The Spitzer Legacy Project From "Molecular Cores to Planet-forming Disks" conducted a 3.6 to 70um photometric survey of roughly 160 weak- line TTauri Stars (wTTs) and 20 classical TTauri stars (cTTs) in the nearby star-forming regions Chamaeleon, Lupus, Ophiuchus and Taurus. WTTs are so named because they possess weaker H-alpha emission lines signifying weaker disk accretion on to the star than cTTs. The evolution of dust disks around these young stars (Age 10 Myrs) is key to understanding planet formation. From the observed infrared excesses, we infer the presence of circumstellar disks around 12% of wTTs and 75% of cTTs. However, when considering on-cloud sources only, the wTTs disk fraction is 22%, while it is only 6% for off- cloud sources, suggesting an older age for the latter. WTTs, while not discernibly younger than cTTs in age diagnostics, in general have disks which exhibit lower fractional luminosities and larger inner clearings. However, quite a few wTTs systems have fractional disk luminosities as high as cTTs systems. In light of these findings, wTTs seem to be transitional objects between cTTs and debris disks.

  2. 2 CFR 25.320 - Entity.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Entity. 25.320 Section 25.320 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET... CONTRACTOR REGISTRATION Definitions § 25.320 Entity. Entity, as it is used in this part, has the meaning...

  3. 24 CFR 320.25 - Securities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Securities. 320.25 Section 320.25... SECURITIES Bond-Type Securities § 320.25 Securities. (a) Instruments. Securities to be issued pursuant to the provisions of this subpart B may be in registered or bearer form. Each security shall have terms acceptable...

  4. 24 CFR 320.25 - Securities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Securities. 320.25 Section 320.25... SECURITIES Bond-Type Securities § 320.25 Securities. (a) Instruments. Securities to be issued pursuant to the provisions of this subpart B may be in registered or bearer form. Each security shall have terms acceptable...

  5. 24 CFR 320.25 - Securities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Securities. 320.25 Section 320.25... SECURITIES Bond-Type Securities § 320.25 Securities. (a) Instruments. Securities to be issued pursuant to the provisions of this subpart B may be in registered or bearer form. Each security shall have terms acceptable...

  6. 24 CFR 320.25 - Securities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Securities. 320.25 Section 320.25... SECURITIES Bond-Type Securities § 320.25 Securities. (a) Instruments. Securities to be issued pursuant to the provisions of this subpart B may be in registered or bearer form. Each security shall have terms acceptable...

  7. 24 CFR 320.25 - Securities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Securities. 320.25 Section 320.25... SECURITIES Bond-Type Securities § 320.25 Securities. (a) Instruments. Securities to be issued pursuant to the provisions of this subpart B may be in registered or bearer form. Each security shall have terms acceptable...

  8. Timing noise measurement of 320 GHz optical pulses using an improved optoelectronic harmonic mixer.

    PubMed

    Tsuchida, Hidemi

    2006-03-01

    An improved optoelectronic harmonic mixer (OEHM) has been employed for measuring the timing noise of 320 GHz optical pulses that are generated from a 160 GHz mode-locked laser diode by the temporal Talbot effect. The OEHM makes use of a low-drive voltage LiNbO3 modulator and a W-band unitraveling carrier photodiode for converting the 320 GHz pulse intensity into a low-frequency electrical signal. The time domain demodulation technique has been used for the precise evaluation of phase noise power spectral density. The rms timing jitter has been estimated to be 311 fs for the 10 Hz-18.6 MHz bandwidth.

  9. 49 CFR 40.241 - What are the first steps in any alcohol screening test?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... facility who is required to have a post-accident test), do not delay this treatment to conduct a test. (c... test? 40.241 Section 40.241 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Alcohol Screening Tests § 40.241 What are the first...

  10. 49 CFR 40.241 - What are the first steps in any alcohol screening test?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... facility who is required to have a post-accident test), do not delay this treatment to conduct a test. (c... test? 40.241 Section 40.241 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Alcohol Screening Tests § 40.241 What are the first...

  11. 49 CFR 40.241 - What are the first steps in any alcohol screening test?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... facility who is required to have a post-accident test), do not delay this treatment to conduct a test. (c... test? 40.241 Section 40.241 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Alcohol Screening Tests § 40.241 What are the first...

  12. 49 CFR 40.241 - What are the first steps in any alcohol screening test?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... facility who is required to have a post-accident test), do not delay this treatment to conduct a test. (c... test? 40.241 Section 40.241 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Alcohol Screening Tests § 40.241 What are the first...

  13. 49 CFR 40.241 - What are the first steps in any alcohol screening test?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... facility who is required to have a post-accident test), do not delay this treatment to conduct a test. (c... test? 40.241 Section 40.241 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Alcohol Screening Tests § 40.241 What are the first...

  14. Nuclear Data Sheets for A=241

    DOE PAGES

    Nesaraja, Caroline D.

    2015-11-27

    This paper presents available information pertaining to the nuclear structure of ground and excited states for all known nuclei with mass numbers A=24, which have been compiled and evaluated. The adopted level and decay schemes, as well as the detailed nuclear properties and configuration assignments based on experimental data are presented for these nuclides. When there are insufficient data, expected values from systematics of nuclear properties or/and theoretical calculations are quoted. Unexpected or discrepant experimental results are also noted. A summary and compilation of the discovery of various isotopes in this mass region is given in 2013Fr02 ( 241Np, 241Pu,more » 241Am, 241Cm, 241Bk, and 241Cf), 2011Me01 (241Es), and 2013Th02 ( 241Fm).« less

  15. Inspection report of unauthorized possession and use of unsealed americium-241 and subsequent confiscation, J. C. Haynes Company, Newark, Ohio

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1985-11-01

    This US Nuclear Regulatory Commission report documents the circumstances surrounding the March 26, 1985, confiscation and subsequent decontamination activities related to the use of unauthorized quantities of americium-241 at the John C. Haynes Company (licensee) of Newark, Ohio. It focuses on the period from early February to July 26, 1985. The incident started when NRC Region III recieved information that John C. Haynes possessed unauthorized quantities of americium-241 and was conducting unauthorized activities (diamond irradiation). By July 26, 1985, the decontamination activities at the licensee's laboratory were concluded. The licensee's actions with diamond irradiation resulted in contamination in restricted andmore » unrestricted areas of the facility. The confiscation and decontamination activities required the combined efforts of NRC, Federal Bureau of Investigation, US Department of Energy, Oak Ridge Associated Universities, the State of Ohio, and the US Environmental Protection Agency. The report describes the factual information and significant findings associated with the confiscation and decontamination activities.« less

  16. DEEP, SHALLOW AND EYE LENS DOSES FROM 106Ru/106Rh-A COMPARSION.

    PubMed

    Kumar, Munish; Bakshi, A K; Rakesh, R B; Ratna, P; Kulkarni, M S; Datta, D

    2017-11-01

    106Ru/106Rh is unique amongst other commonly used beta sources such as 147Pm, 85Kr, 204Tl, 32P, natU and 90Sr/90Y in the sense that it is capable of simultaneously delivering shallow/skin, eye lens and deep/whole body doses (WBDs) and they differ from each other substantially. In view of this, the investigation of various quantities defined for individual monitoring is possible and this makes 106Ru/106Rh beta source, a classical example in radiation protection and dosimetry. This led us to estimate skin, eye lens and WBDs for 106Ru/106Rh beta source. Optically stimulated luminescence based ultra-thin α-Al2O3:C disc dosimeters were used in the present study. Typical values (relative) of the eye lens and whole body/deep doses with respective to the skin dose (100%) were experimentally measured as ~66 ± 4.6% and 17 ± 3.9%, respectively. The study shows that 106Ru/106Rh beta source is capable of delivering even WBD which is not the case with other beta sources. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  17. PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex.

    PubMed

    Surapureddi, Sailesh; Viswakarma, Navin; Yu, Songtao; Guo, Dongsheng; Rao, M Sambasiva; Reddy, Janardan K

    2006-05-05

    Ciprofibrate, a potent peroxisome proliferator, induces pleiotropic responses in liver by activating peroxisome proliferator-activated receptor alpha (PPARalpha), a nuclear receptor. Transcriptional regulation by liganded nuclear receptors involves the participation of coregulators that form multiprotein complexes possibly to achieve cell and gene specific transcription. SDS-PAGE and matrix-assisted laser desorption/ionization reflection time-of-flight mass spectrometric analyses of ciprofibrate-binding proteins from liver nuclear extracts obtained using ciprofibrate-Sepharose affinity matrix resulted in the identification of a new high molecular weight nuclear receptor coactivator, which we designated PRIC320. The full-length human cDNA encoding this protein has an open-reading frame that codes for a 320kDa protein containing 2882 amino acids. PRIC320 contains five LXXLL signature motifs that mediate interaction with nuclear receptors. PRIC320 binds avidly to nuclear receptors PPARalpha, CAR, ERalpha, and RXR, but only minimally with PPARgamma. PRIC320 also interacts with transcription cofactors CBP, PRIP, and PBP. Immunoprecipitation-immunoblotting as well as cellular localization studies confirmed the interaction between PPARalpha and PRIC320. PRIC320 acts as a transcription coactivator by stimulating PPARalpha-mediated transcription. We conclude that ciprofibrate, a PPARalpha ligand, binds a multiprotein complex and PRIC320 cloned from this complex functions as a nuclear receptor coactivator.

  18. 49 CFR Appendix B to Part 234 - Alternate Methods of Protection Under 49 CFR 234.105(c), 234.106, and 234.107(c)

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Protection Under 49 CFR 234.105(c), 234.106, and 234.107(c) [This is a summary—see body of text for complete... pair of lights designed to flash alternatively, one light does not work (and back-lights from other...

  19. Results of Characterization and Retrieval Testing on Tank 241-C-110 Heel Solids

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Callaway, William S.

    2013-09-30

    Nine samples of heel solids from tank 241-C-110 were delivered to the 222-S Laboratory for characterization and dissolution testing. After being drained thoroughly, the sample solids were primarily white to light-brown with minor dark-colored inclusions. The maximum dimension of the majority of the solids was <2 mm; however, numerous pieces of aggregate, microcrystalline, and crystalline solids with maximum dimensions ranging from 5-70 mm were observed. In general, the larger pieces of aggregate solids were strongly cemented. Natrophosphate [Na{sub 7}F(PO{sub 4}){sub 2}°19H{sub 2}O] was the dominant solid phase identified in the heel solids. Results of chemical analyses suggested that 85-87 wt%more » of the heel solids were the fluoridephosphate double salt. The average bulk density measured for the heel solids was 1.689 g/mL; the reference density of natrophosphate is 1.71 g/mL. Dissolution tests on composite samples indicate that 94 to 97 wt% of the tank 241-C-110 heel solids can be retrieved by dissolution in water. Dissolution and recovery of the soluble components in 1 kg (0.59 L) of the heel solids required the addition of ≈9.5 kg (9.5 L) of water at 15 °C and ≈4.4 kg (4.45 L) of water at 45 °C. Calculations performed using the Environmental Simulation Program indicate that dissolution of the ≈0.86 kg of natrophosphate in each kilogram of the tank 241-C-110 heel solids would require ≈9.45 kg of water at 15 °C and ≈4.25 kg of water at 45 °C. The slightly larger quantities of water determined to be required to retrieve the soluble components in 1 kg of the heel solids are consistent with that required for the dissolution of solids composed mainly of natrophosphate with a major portion of the balance consisting of highly soluble sodium salts. At least 98% of the structural water, soluble phosphate, sodium, fluoride, nitrate, carbonate, nitrite, sulfate, oxalate, and chloride in the test composites was dissolved and recovered in the dissolution

  20. Complex Effects of 24:1 Sphingolipids in Membranes Containing Dioleoylphosphatidylcholine and Cholesterol.

    PubMed

    García-Arribas, Aritz B; González-Ramírez, Emilio J; Sot, Jesús; Areso, Itziar; Alonso, Alicia; Goñi, Félix M

    2017-06-06

    The effects of C24:1 sphingolipids have been tested in phospholipid bilayers containing cholesterol. Confocal microscopy, differential scanning calorimetry, and atomic force microscopy imaging and force curves have been used. More precisely, the effects of C24:1 ceramide (nervonoyl ceramide, nCer) were evaluated and compared to those of C16:0 ceramide (palmitoyl ceramide, pCer) in bilayers composed basically of dioleoylphosphatidylcholine, sphingomyelin (either C24:1, nSM or C16:0, pSM) and cholesterol. Combination of equimolecular amounts of C24:1 and C16:0 sphingolipids were also studied under the same conditions. Results show that both pCer and nCer are capable of forming segregated gel domains. Force spectroscopy data point to nCer having a lower stiffening effect than pCer, while the presence of nSM reduces the stiffness. DSC reveals T m reduction by nSM in every case. Furthermore, pSM seems to better accommodate both ceramides in a single phase of intermediate properties, while nSM partial accommodation of ceramides generates different gel phases with higher stiffnesses caused by interceramide cooperation. If both pSM and nSM are present, a clear preference of both ceramides toward pSM is observed. These findings show the sharp increase in complexity when membranes exhibit different sphingolipids of varying N-acyl chains, which should be a common issue in an actual cell membrane environment.

  1. Measurement of exclusive γ γ →W+W- production and search for exclusive Higgs boson production in p p collisions at √{s }=8 TeV using the ATLAS detector

    NASA Astrophysics Data System (ADS)

    Aaboud, M.; Aad, G.; Abbott, B.; Abdallah, J.; Abdinov, O.; Abeloos, B.; Aben, R.; Abouzeid, O. S.; Abraham, N. L.; Abramowicz, H.; Abreu, H.; Abreu, R.; Abulaiti, Y.; Acharya, B. S.; Adamczyk, L.; Adams, D. L.; Adelman, J.; Adomeit, S.; Adye, T.; Affolder, A. A.; Agatonovic-Jovin, T.; Agricola, J.; Aguilar-Saavedra, J. A.; Ahlen, S. P.; Ahmadov, F.; Aielli, G.; Akerstedt, H.; Åkesson, T. P. A.; Akimov, A. V.; Alberghi, G. L.; Albert, J.; Albrand, S.; Alconada Verzini, M. J.; Aleksa, M.; Aleksandrov, I. N.; Alexa, C.; Alexander, G.; Alexopoulos, T.; Alhroob, M.; Ali, B.; Aliev, M.; Alimonti, G.; Alison, J.; Alkire, S. P.; Allbrooke, B. M. M.; Allen, B. W.; Allport, P. P.; Aloisio, A.; Alonso, A.; Alonso, F.; Alpigiani, C.; Alstaty, M.; Alvarez Gonzalez, B.; Álvarez Piqueras, D.; Alviggi, M. G.; Amadio, B. T.; Amako, K.; Amaral Coutinho, Y.; Amelung, C.; Amidei, D.; Amor Dos Santos, S. P.; Amorim, A.; Amoroso, S.; Amundsen, G.; Anastopoulos, C.; Ancu, L. S.; Andari, N.; Andeen, T.; Anders, C. F.; Anders, G.; Anders, J. K.; Anderson, K. J.; Andreazza, A.; Andrei, V.; Angelidakis, S.; Angelozzi, I.; Anger, P.; Angerami, A.; Anghinolfi, F.; Anisenkov, A. V.; Anjos, N.; Annovi, A.; Antel, C.; Antonelli, M.; Antonov, A.; Anulli, F.; Aoki, M.; Aperio Bella, L.; Arabidze, G.; Arai, Y.; Araque, J. P.; Arce, A. T. H.; Arduh, F. A.; Arguin, J.-F.; Argyropoulos, S.; Arik, M.; Armbruster, A. J.; Armitage, L. J.; Arnaez, O.; Arnold, H.; Arratia, M.; Arslan, O.; Artamonov, A.; Artoni, G.; Artz, S.; Asai, S.; Asbah, N.; Ashkenazi, A.; Åsman, B.; Asquith, L.; Assamagan, K.; Astalos, R.; Atkinson, M.; Atlay, N. B.; Augsten, K.; Avolio, G.; Axen, B.; Ayoub, M. K.; Azuelos, G.; Baak, M. A.; Baas, A. E.; Baca, M. J.; Bachacou, H.; Bachas, K.; Backes, M.; Backhaus, M.; Bagiacchi, P.; Bagnaia, P.; Bai, Y.; Baines, J. T.; Baker, O. K.; Baldin, E. M.; Balek, P.; Balestri, T.; Balli, F.; Balunas, W. K.; Banas, E.; Banerjee, Sw.; Bannoura, A. A. E.; Barak, L.; Barberio, E. L.; Barberis, D.; Barbero, M.; Barillari, T.; Barisits, M.-S.; Barklow, T.; Barlow, N.; Barnes, S. L.; Barnett, B. M.; Barnett, R. M.; Barnovska, Z.; Baroncelli, A.; Barone, G.; Barr, A. J.; Barranco Navarro, L.; Barreiro, F.; Barreiro Guimarães da Costa, J.; Bartoldus, R.; Barton, A. E.; Bartos, P.; Basalaev, A.; Bassalat, A.; Bates, R. L.; Batista, S. J.; Batley, J. R.; Battaglia, M.; Bauce, M.; Bauer, F.; Bawa, H. S.; Beacham, J. B.; Beattie, M. D.; Beau, T.; Beauchemin, P. H.; Bechtle, P.; Beck, H. P.; Becker, K.; Becker, M.; Beckingham, M.; Becot, C.; Beddall, A. J.; Beddall, A.; Bednyakov, V. A.; Bedognetti, M.; Bee, C. P.; Beemster, L. J.; Beermann, T. A.; Begel, M.; Behr, J. K.; Belanger-Champagne, C.; Bell, A. S.; Bella, G.; Bellagamba, L.; Bellerive, A.; Bellomo, M.; Belotskiy, K.; Beltramello, O.; Belyaev, N. L.; Benary, O.; Benchekroun, D.; Bender, M.; Bendtz, K.; Benekos, N.; Benhammou, Y.; Benhar Noccioli, E.; Benitez, J.; Benjamin, D. P.; Bensinger, J. R.; Bentvelsen, S.; Beresford, L.; Beretta, M.; Berge, D.; Bergeaas Kuutmann, E.; Berger, N.; Beringer, J.; Berlendis, S.; Bernard, N. R.; Bernius, C.; Bernlochner, F. U.; Berry, T.; Berta, P.; Bertella, C.; Bertoli, G.; Bertolucci, F.; Bertram, I. A.; Bertsche, C.; Bertsche, D.; Besjes, G. J.; Bessidskaia Bylund, O.; Bessner, M.; Besson, N.; Betancourt, C.; Bethani, A.; Bethke, S.; Bevan, A. J.; Bianchi, R. M.; Bianchini, L.; Bianco, M.; Biebel, O.; Biedermann, D.; Bielski, R.; Biesuz, N. V.; Biglietti, M.; Bilbao de Mendizabal, J.; Billoud, T. R. V.; Bilokon, H.; Bindi, M.; Binet, S.; Bingul, A.; Bini, C.; Biondi, S.; Bisanz, T.; Bjergaard, D. M.; Black, C. W.; Black, J. E.; Black, K. M.; Blackburn, D.; Blair, R. E.; Blanchard, J.-B.; Blazek, T.; Bloch, I.; Blocker, C.; Blum, W.; Blumenschein, U.; Blunier, S.; Bobbink, G. J.; Bobrovnikov, V. S.; Bocchetta, S. S.; Bocci, A.; Bock, C.; Boehler, M.; Boerner, D.; Bogaerts, J. A.; Bogavac, D.; Bogdanchikov, A. G.; Bohm, C.; Boisvert, V.; Bokan, P.; Bold, T.; Boldyrev, A. S.; Bomben, M.; Bona, M.; Boonekamp, M.; Borisov, A.; Borissov, G.; Bortfeldt, J.; Bortoletto, D.; Bortolotto, V.; Bos, K.; Boscherini, D.; Bosman, M.; Bossio Sola, J. D.; Boudreau, J.; Bouffard, J.; Bouhova-Thacker, E. V.; Boumediene, D.; Bourdarios, C.; Boutle, S. K.; Boveia, A.; Boyd, J.; Boyko, I. R.; Bracinik, J.; Brandt, A.; Brandt, G.; Brandt, O.; Bratzler, U.; Brau, B.; Brau, J. E.; Braun, H. M.; Breaden Madden, W. D.; Brendlinger, K.; Brennan, A. J.; Brenner, L.; Brenner, R.; Bressler, S.; Bristow, T. M.; Britton, D.; Britzger, D.; Brochu, F. M.; Brock, I.; Brock, R.; Brooijmans, G.; Brooks, T.; Brooks, W. K.; Brosamer, J.; Brost, E.; Broughton, J. H.; Bruckman de Renstrom, P. A.; Bruncko, D.; Bruneliere, R.; Bruni, A.; Bruni, G.; Bruni, L. S.; Brunt, Bh; Bruschi, M.; Bruscino, N.; Bryant, P.; Bryngemark, L.; Buanes, T.; Buat, Q.; Buchholz, P.; Buckley, A. G.; Budagov, I. A.; Buehrer, F.; Bugge, M. K.; Bulekov, O.; Bullock, D.; Burckhart, H.; Burdin, S.; Burgard, C. D.; Burghgrave, B.; Burka, K.; Burke, S.; Burmeister, I.; Burr, J. T. P.; Busato, E.; Büscher, D.; Büscher, V.; Bussey, P.; Butler, J. M.; Buttar, C. M.; Butterworth, J. M.; Butti, P.; Buttinger, W.; Buzatu, A.; Buzykaev, A. R.; Cabrera Urbán, S.; Caforio, D.; Cairo, V. M.; Cakir, O.; Calace, N.; Calafiura, P.; Calandri, A.; Calderini, G.; Calfayan, P.; Callea, G.; Caloba, L. P.; Calvente Lopez, S.; Calvet, D.; Calvet, S.; Calvet, T. P.; Camacho Toro, R.; Camarda, S.; Camarri, P.; Cameron, D.; Caminal Armadans, R.; Camincher, C.; Campana, S.; Campanelli, M.; Camplani, A.; Campoverde, A.; Canale, V.; Canepa, A.; Cano Bret, M.; Cantero, J.; Cantrill, R.; Cao, T.; Capeans Garrido, M. D. M.; Caprini, I.; Caprini, M.; Capua, M.; Caputo, R.; Carbone, R. M.; Cardarelli, R.; Cardillo, F.; Carli, I.; Carli, T.; Carlino, G.; Carminati, L.; Caron, S.; Carquin, E.; Carrillo-Montoya, G. D.; Carter, J. R.; Carvalho, J.; Casadei, D.; Casado, M. P.; Casolino, M.; Casper, D. W.; Castaneda-Miranda, E.; Castelijn, R.; Castelli, A.; Castillo Gimenez, V.; Castro, N. F.; Catinaccio, A.; Catmore, J. R.; Cattai, A.; Caudron, J.; Cavaliere, V.; Cavallaro, E.; Cavalli, D.; Cavalli-Sforza, M.; Cavasinni, V.; Ceradini, F.; Cerda Alberich, L.; Cerio, B. C.; Cerqueira, A. S.; Cerri, A.; Cerrito, L.; Cerutti, F.; Cerv, M.; Cervelli, A.; Cetin, S. A.; Chafaq, A.; Chakraborty, D.; Chan, S. K.; Chan, Y. L.; Chang, P.; Chapman, J. D.; Charlton, D. G.; Chatterjee, A.; Chau, C. C.; Chavez Barajas, C. A.; Che, S.; Cheatham, S.; Chegwidden, A.; Chekanov, S.; Chekulaev, S. V.; Chelkov, G. A.; Chelstowska, M. A.; Chen, C.; Chen, H.; Chen, K.; Chen, S.; Chen, S.; Chen, X.; Chen, Y.; Cheng, H. C.; Cheng, H. J.; Cheng, Y.; Cheplakov, A.; Cheremushkina, E.; Cherkaoui El Moursli, R.; Chernyatin, V.; Cheu, E.; Chevalier, L.; Chiarella, V.; Chiarelli, G.; Chiodini, G.; Chisholm, A. S.; Chitan, A.; Chizhov, M. V.; Choi, K.; Chomont, A. R.; Chouridou, S.; Chow, B. K. B.; Christodoulou, V.; Chromek-Burckhart, D.; Chudoba, J.; Chuinard, A. J.; Chwastowski, J. J.; Chytka, L.; Ciapetti, G.; Ciftci, A. K.; Cinca, D.; Cindro, V.; Cioara, I. A.; Ciocca, C.; Ciocio, A.; Cirotto, F.; Citron, Z. H.; Citterio, M.; Ciubancan, M.; Clark, A.; Clark, B. L.; Clark, M. R.; Clark, P. J.; Clarke, R. N.; Clement, C.; Coadou, Y.; Cobal, M.; Coccaro, A.; Cochran, J.; Colasurdo, L.; Cole, B.; Colijn, A. P.; Collot, J.; Colombo, T.; Compostella, G.; Conde Muiño, P.; Coniavitis, E.; Connell, S. H.; Connelly, I. A.; Consorti, V.; Constantinescu, S.; Conti, G.; Conventi, F.; Cooke, M.; Cooper, B. D.; Cooper-Sarkar, A. M.; Cormier, K. J. R.; Cornelissen, T.; Corradi, M.; Corriveau, F.; Corso-Radu, A.; Cortes-Gonzalez, A.; Cortiana, G.; Costa, G.; Costa, M. J.; Costanzo, D.; Cottin, G.; Cowan, G.; Cox, B. E.; Cranmer, K.; Crawley, S. J.; Cree, G.; Crépé-Renaudin, S.; Crescioli, F.; Cribbs, W. A.; Crispin Ortuzar, M.; Cristinziani, M.; Croft, V.; Crosetti, G.; Cueto, A.; Cuhadar Donszelmann, T.; Cummings, J.; Curatolo, M.; Cúth, J.; Czirr, H.; Czodrowski, P.; D'Amen, G.; D'Auria, S.; D'Onofrio, M.; da Cunha Sargedas de Sousa, M. J.; da Via, C.; Dabrowski, W.; Dado, T.; Dai, T.; Dale, O.; Dallaire, F.; Dallapiccola, C.; Dam, M.; Dandoy, J. R.; Dang, N. P.; Daniells, A. C.; Dann, N. S.; Danninger, M.; Dano Hoffmann, M.; Dao, V.; Darbo, G.; Darmora, S.; Dassoulas, J.; Dattagupta, A.; Davey, W.; David, C.; Davidek, T.; Davies, M.; Davison, P.; Dawe, E.; Dawson, I.; Daya-Ishmukhametova, R. K.; de, K.; de Asmundis, R.; de Benedetti, A.; de Castro, S.; de Cecco, S.; de Groot, N.; de Jong, P.; de la Torre, H.; de Lorenzi, F.; de Maria, A.; de Pedis, D.; de Salvo, A.; de Sanctis, U.; de Santo, A.; de Vivie de Regie, J. B.; Dearnaley, W. J.; Debbe, R.; Debenedetti, C.; Dedovich, D. 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A.; Viel, S.; Vigani, L.; Villa, M.; Villaplana Perez, M.; Vilucchi, E.; Vincter, M. G.; Vinogradov, V. B.; Vittori, C.; Vivarelli, I.; Vlachos, S.; Vlasak, M.; Vogel, M.; Vokac, P.; Volpi, G.; Volpi, M.; von der Schmitt, H.; von Toerne, E.; Vorobel, V.; Vorobev, K.; Vos, M.; Voss, R.; Vossebeld, J. H.; Vranjes, N.; Vranjes Milosavljevic, M.; Vrba, V.; Vreeswijk, M.; Vuillermet, R.; Vukotic, I.; Vykydal, Z.; Wagner, P.; Wagner, W.; Wahlberg, H.; Wahrmund, S.; Wakabayashi, J.; Walder, J.; Walker, R.; Walkowiak, W.; Wallangen, V.; Wang, C.; Wang, C.; Wang, F.; Wang, H.; Wang, H.; Wang, J.; Wang, J.; Wang, K.; Wang, R.; Wang, S. M.; Wang, T.; Wang, T.; Wang, W.; Wang, X.; Wanotayaroj, C.; Warburton, A.; Ward, C. P.; Wardrope, D. R.; Washbrook, A.; Watkins, P. M.; Watson, A. T.; Watson, M. F.; Watts, G.; Watts, S.; Waugh, B. M.; Webb, S.; Weber, M. S.; Weber, S. W.; Webster, J. S.; Weidberg, A. R.; Weinert, B.; Weingarten, J.; Weiser, C.; Weits, H.; Wells, P. 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H.; Ye, J.; Ye, S.; Yeletskikh, I.; Yen, A. L.; Yildirim, E.; Yorita, K.; Yoshida, R.; Yoshihara, K.; Young, C.; Young, C. J. S.; Youssef, S.; Yu, D. R.; Yu, J.; Yu, J. M.; Yu, J.; Yuan, L.; Yuen, S. P. Y.; Yusuff, I.; Zabinski, B.; Zaidan, R.; Zaitsev, A. M.; Zakharchuk, N.; Zalieckas, J.; Zaman, A.; Zambito, S.; Zanello, L.; Zanzi, D.; Zeitnitz, C.; Zeman, M.; Zemla, A.; Zeng, J. C.; Zeng, Q.; Zengel, K.; Zenin, O.; Ženiš, T.; Zerwas, D.; Zhang, D.; Zhang, F.; Zhang, G.; Zhang, H.; Zhang, J.; Zhang, L.; Zhang, R.; Zhang, R.; Zhang, X.; Zhang, Z.; Zhao, X.; Zhao, Y.; Zhao, Z.; Zhemchugov, A.; Zhong, J.; Zhou, B.; Zhou, C.; Zhou, L.; Zhou, L.; Zhou, M.; Zhou, N.; Zhu, C. G.; Zhu, H.; Zhu, J.; Zhu, Y.; Zhuang, X.; Zhukov, K.; Zibell, A.; Zieminska, D.; Zimine, N. I.; Zimmermann, C.; Zimmermann, S.; Zinonos, Z.; Zinser, M.; Ziolkowski, M.; Živković, L.; Zobernig, G.; Zoccoli, A.; Zur Nedden, M.; Zwalinski, L.; Atlas Collaboration

    2016-08-01

    Searches for exclusively produced W boson pairs in the process p p (γ γ )→p W+W-p and an exclusively produced Higgs boson in the process p p (g g )→p H p have been performed using e±μ∓ final states. These measurements use 20.2 fb-1 of p p collisions collected by the ATLAS experiment at a center-of-mass energy √{s }=8 TeV at the LHC. Exclusive production of W+W- consistent with the Standard Model prediction is found with 3.0 σ significance. The exclusive W+W- production cross section is determined to be σ (γ γ →W+W-→e±μ∓X )=6.9 ±2.2 (stat )±1.4 (sys ) fb , in agreement with the Standard Model prediction. Limits on anomalous quartic gauge couplings are set at 95% confidence level as -1.7 ×10-6W/Λ2<1.7 ×10-6 GeV-2 and -6.4 ×10-610-6 GeV-2 . A 95% confidence-level upper limit on the total production cross section for an exclusive Higgs boson is set to 1.2 pb.

  2. CESIUM REMOVAL FROM TANKS 241-AN-103 & 241-SX-105 & 241-AZ-101/102 COMPOSITE FOR TESTING IN BENCH SCALE STEAM REFORMER

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DUNCAN JB; HUBER HJ

    2011-06-08

    This report documents the preparation of three actual Hanford tank waste samples for shipment to the Savannah River National Laboratory (SRNL). Two of the samples were dissolved saltcakes from tank 241-AN-103 (hereafter AN-103) and tank 241-SX-105 (hereafter SX-105); one sample was a supernate composite from tanks 241-AZ-101 and 241-AZ-102 (hereafter AZ-101/102). The preparation of the samples was executed following the test plans LAB-PLAN-10-00006, Test Plan for the Preparation of Samples from Hanford Tanks 241-SX-105, 241-AN-103, 241-AN-107, and LAB-PLN-10-00014, Test Plan for the Preparation of a Composite Sample from Hanford Tanks 241-AZ-101 and 241-AZ-102 for Steam Reformer Testing at the Savannahmore » River National Laboratory. All procedural steps were recorded in laboratory notebook HNF-N-274 3. Sample breakdown diagrams for AN-103 and SX-105 are presented in Appendix A. The tank samples were prepared in support of a series of treatability studies of the Fluidized Bed Steam Reforming (FBSR) process using a Bench-Scale Reformer (BSR) at SRNL. Tests with simulants have shown that the FBSR mineralized waste form is comparable to low-activity waste glass with respect to environmental durability (WSRC-STI-2008-00268, Mineralization of Radioactive Wastes by Fluidized Bed Steam Reforming (FBSR): Comparisons to Vitreous Waste Forms and Pertinent Durability Testing). However, a rigorous assessment requires long-term performance data from FB SR product formed from actual Hanford tank waste. Washington River Protection Solutions, LLC (WRPS) has initiated a Waste Form Qualification Program (WP-S.2.1-20 1 0-00 1, Fluidized Bed Steam Reformer Low-level Waste Form Qualification) to gather the data required to demonstrate that an adequate FBSR mineralized waste form can be produced. The documentation of the selection process of the three tank samples has been separately reported in RPP-48824, 'Sample Selection Process for Bench-Scale Steam Reforming Treatability Studies

  3. 48 CFR 241.201 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Policy. 241.201 Section 241.201 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF UTILITY SERVICES Acquiring Utility Services 241...

  4. STS-106 crew spends time at SPACEHAB for CEIT

    NASA Technical Reports Server (NTRS)

    2000-01-01

    As part of Crew Equipment Interface Test (CEIT) activities at SPACEHAB, members of the STS-106 crew check out a Maximum Envelope Support Structure (MESS) rack they will be using during their mission to the International Space Station. Seen here (with backs to camera, in uniform) are Mission Specialist Richard A. Mastracchio, Pilot Scott D. Altman, Boris V. Morukov, and Edward T. Lu (at right). Also taking part in the CEIT are Commander Terrence W. Wilcutt and Mission Specialists Yuri I. Malenchenko and Daniel C. Burbank. Malenchenko and Morukov represent the Russian Aviation and Space Agency. STS-106 is scheduled to launch Sept. 8, 2000, at 8:31 a.m. EDT from Launch Pad 39B on an 11-day mission. The seven-member crew will prepare the Space Station for its first resident crew and begin outfitting the newly arrived Zvezda Service Module. They will perform support tasks on orbit, transfer supplies and prepare the Zvezda living quarters for the first long-duration crew, dubbed '''Expedition One,''' which is due to arrive at the Station in late fall.

  5. Transmit/receive 3-20 GHz 1.2 mW packaged double-pole-16-throw switching matrix for radar-based target detection

    NASA Astrophysics Data System (ADS)

    Azhari, Afreen; Kuwano, Yuki; Xiao, Xia; Kikkawa, Takamaro

    2018-01-01

    A 3-20 GHz transmit/receive (T/R) double-pole-16-throw (DP16T) switching matrix has been developed on a printed circuit board (PCB) to control sixteen antennas in a radar-based portable breast-cancer detection system. The DP16T switch consists of four 65 nm CMOS 0.01-20 GHz double-pole-four-throw (DP4T) switches. The proposed switch increase the number of T/R combinations to 224 from the 196 of a conventional switching matrix in order to construct high-resolution images. Using this switch and a 4 × 4 slot antenna array, a 10 × 10 mm2 aluminum target was detected with an 8-GHz-center-frequency Gaussian monocycle pulse. The power consumption of the switch is only 1.2 mW. To the best of the authors’ knowledge, this is the first T/R radio frequency (RF) DP16T switching matrix, which was realized with four CMOS DP4T switches on a PCB and was measured with RF PCB connectors.

  6. In silico analysis of AHJD-like viruses, Staphylococcus aureus phages S24-1 and S13′, and study of phage S24-1 adsorption

    PubMed Central

    Uchiyama, Jumpei; Takemura-Uchiyama, Iyo; Kato, Shin-ichiro; Sato, Miho; Ujihara, Takako; Matsui, Hidehito; Hanaki, Hideaki; Daibata, Masanori; Matsuzaki, Shigenobu

    2014-01-01

    Staphylococcus aureus is a clinically important bacterium that is commensal in both humans and animals. Bacteriophage (phage) attachment to the host bacterial surface is an important process during phage infection, which involves interactions between phage receptor-binding proteins and host receptor molecules. However, little information is available on the receptor-binding protein of S. aureus phages. S. aureus virulent phages S24-1 and S13′ (family Podoviridae, genus AHJD-like viruses) were isolated from sewage. In the present study, we investigated the receptor-binding protein of AHJD-like viruses using phage S24-1. First, based on a comparative genomic analysis of phages S24-1 and S13′, open reading frame 16 (ORF16) of phage S24-1 was speculated to be the receptor-binding protein, which possibly determines the host range. Second, we demonstrated that this was the receptor-binding protein of phage S24-1. Third, our study suggested that wall teichoic acids in the cell walls of S. aureus are the main receptor molecules for ORF16 and phage S24-1. Finally, the C-terminal region of ORF16 may be essential for binding to S. aureus. These results strongly suggest that ORF16 of phage S24-1 and its homologs may be the receptor-binding proteins of AHJD-like viruses. PMID:24591378

  7. 47 CFR 87.241 - Frequencies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Frequencies. 87.241 Section 87.241 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AVIATION SERVICES Aeronautical Multicom Stations § 87.241 Frequencies. (a) 121.500 MHz: emergency and distress only; (b) 122.850...

  8. 46 CFR 169.241 - Machinery.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Machinery. 169.241 Section 169.241 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Inspection and Certification Inspections § 169.241 Machinery. (a) At each inspection for certification and periodic inspection...

  9. 46 CFR 169.241 - Machinery.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Machinery. 169.241 Section 169.241 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Inspection and Certification Inspections § 169.241 Machinery. (a) At each inspection for certification and periodic inspection...

  10. 7 CFR 1220.241 - Reports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Reports. 1220.241 Section 1220.241 Agriculture... CONSUMER INFORMATION Soybean Promotion and Research Order Reports, Books, and Records § 1220.241 Reports... to report to the Board periodically such information as may be required by the regulations...

  11. 7 CFR 1220.241 - Reports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Reports. 1220.241 Section 1220.241 Agriculture... CONSUMER INFORMATION Soybean Promotion and Research Order Reports, Books, and Records § 1220.241 Reports... to report to the Board periodically such information as may be required by the regulations...

  12. 10 CFR 1021.320 - Environmental assessments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Environmental assessments. 1021.320 Section 1021.320 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NATIONAL ENVIRONMENTAL POLICY ACT IMPLEMENTING PROCEDURES Implementing Procedures § 1021.320 Environmental assessments. DOE shall prepare and circulate EAs...

  13. 10 CFR 1021.320 - Environmental assessments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Environmental assessments. 1021.320 Section 1021.320 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NATIONAL ENVIRONMENTAL POLICY ACT IMPLEMENTING PROCEDURES Implementing Procedures § 1021.320 Environmental assessments. DOE shall prepare and circulate EAs...

  14. 42 CFR 24.1 - Establishment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Establishment. 24.1 Section 24.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.1 Establishment. There is established in the Public Health Service (PHS) a Senior Biomedical...

  15. 42 CFR 24.1 - Establishment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Establishment. 24.1 Section 24.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.1 Establishment. There is established in the Public Health Service (PHS) a Senior Biomedical...

  16. 42 CFR 24.1 - Establishment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Establishment. 24.1 Section 24.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.1 Establishment. There is established in the Public Health Service (PHS) a Senior Biomedical...

  17. 42 CFR 24.1 - Establishment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Establishment. 24.1 Section 24.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.1 Establishment. There is established in the Public Health Service (PHS) a Senior Biomedical...

  18. Eclipse project QF-106 and C-141A takeoff on first tethered flight December 20, 1997

    NASA Technical Reports Server (NTRS)

    1997-01-01

    TOW ROPE TAKEOFF - The Kelly Space & Technology (KST)/USAF Eclipse project's modified QF-106 and a USAF C-141A takeoff for the project's first tethered flight on December 20, 1997. The successful 18-minute-long flight reached an altitude of 10,000 feet. NASA's Dryden Flight Research Center, Edwards, California, hosted the project, providing engineering and facility support as well as the project pilot. In 1997 and 1998, the Dryden Flight Research Center at Edwards, California, supported and hosted a Kelly Space & Technology, Inc. project called Eclipse, which sought to demonstrate the feasibility of a reusable tow-launch vehicle concept. The project goal was to successfully tow, inflight, a modified QF-106 delta-wing aircraft with an Air Force C-141A transport aircraft. This would demonstrate the possibility of towing and launching an actual launch vehicle from behind a tow plane. Dryden was the responsible test organization and had flight safety responsibility for the Eclipse project. Dryden provided engineering, instrumentation, simulation, modification, maintenance, range support, and research pilots for the test program. The Air Force Flight Test Center (AFFTC), Edwards, California, supplied the C-141A transport aircraft and crew and configured the aircraft as needed for the tests. The AFFTC also provided the concept and detail design and analysis as well as hardware for the tow system and QF-106 modifications. Dryden performed the modifications to convert the QF-106 drone into the piloted EXD-01 (Eclipse eXperimental Demonstrator-01) experimental aircraft. Kelly Space & Technology hoped to use the results gleaned from the tow test in developing a series of low-cost, reusable launch vehicles. These tests demonstrated the validity of towing a delta-wing aircraft having high wing loading, validated the tow simulation model, and demonstrated various operational procedures, such as ground processing of in-flight maneuvers and emergency abort scenarios.

  19. IRIG 106 Chapter 10 Programmers Handbook

    DTIC Science & Technology

    2016-08-16

    card number that controls the desired SCSI device. When 10 Internet Engineering Task Force...idmptmat - Read and dump a TMATS record from an IRIG 106 Ch 10 data file Copyright (c) 2006 Irig106.org All rights reserved

  20. 7 CFR 58.320 - Brine tanks.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Brine tanks. 58.320 Section 58.320 Agriculture....320 Brine tanks. Brine tanks used for the treating of parchment liners shall be constructed of... liners. The tank should also be provided with a satisfactory drainage outlet. ...

  1. 7 CFR 58.320 - Brine tanks.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Brine tanks. 58.320 Section 58.320 Agriculture....320 Brine tanks. Brine tanks used for the treating of parchment liners shall be constructed of... liners. The tank should also be provided with a satisfactory drainage outlet. ...

  2. 7 CFR 58.320 - Brine tanks.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Brine tanks. 58.320 Section 58.320 Agriculture....320 Brine tanks. Brine tanks used for the treating of parchment liners shall be constructed of... liners. The tank should also be provided with a satisfactory drainage outlet. ...

  3. 7 CFR 58.320 - Brine tanks.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Brine tanks. 58.320 Section 58.320 Agriculture....320 Brine tanks. Brine tanks used for the treating of parchment liners shall be constructed of... liners. The tank should also be provided with a satisfactory drainage outlet. ...

  4. 7 CFR 58.320 - Brine tanks.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Brine tanks. 58.320 Section 58.320 Agriculture....320 Brine tanks. Brine tanks used for the treating of parchment liners shall be constructed of... liners. The tank should also be provided with a satisfactory drainage outlet. ...

  5. 46 CFR 128.320 - Exhaust systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Exhaust systems. 128.320 Section 128.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS MARINE ENGINEERING: EQUIPMENT AND SYSTEMS Main and Auxiliary Machinery § 128.320 Exhaust systems. No diesel-engine exhaust system...

  6. 46 CFR 128.320 - Exhaust systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Exhaust systems. 128.320 Section 128.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS MARINE ENGINEERING: EQUIPMENT AND SYSTEMS Main and Auxiliary Machinery § 128.320 Exhaust systems. No diesel-engine exhaust system...

  7. 46 CFR 128.320 - Exhaust systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Exhaust systems. 128.320 Section 128.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS MARINE ENGINEERING: EQUIPMENT AND SYSTEMS Main and Auxiliary Machinery § 128.320 Exhaust systems. No diesel-engine exhaust system...

  8. 46 CFR 128.320 - Exhaust systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Exhaust systems. 128.320 Section 128.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS MARINE ENGINEERING: EQUIPMENT AND SYSTEMS Main and Auxiliary Machinery § 128.320 Exhaust systems. No diesel-engine exhaust system...

  9. 46 CFR 128.320 - Exhaust systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Exhaust systems. 128.320 Section 128.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS MARINE ENGINEERING: EQUIPMENT AND SYSTEMS Main and Auxiliary Machinery § 128.320 Exhaust systems. No diesel-engine exhaust system...

  10. 47 CFR 3.20 - Application form.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Application Procedures § 3.20 Application form. Written application must be made to the Federal Communications Commission on FCC Form 44... 47 Telecommunication 1 2010-10-01 2010-10-01 false Application form. 3.20 Section 3.20...

  11. 7 CFR 1205.320 - Marketing year.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Marketing year. 1205.320 Section 1205.320 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Research and Promotion Order Definitions § 1205.320 Marketing year. Marketing year means a consecutive 12...

  12. 7 CFR 1205.320 - Marketing year.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Marketing year. 1205.320 Section 1205.320 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Research and Promotion Order Definitions § 1205.320 Marketing year. Marketing year means a consecutive 12...

  13. 7 CFR 1205.320 - Marketing year.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Marketing year. 1205.320 Section 1205.320 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Research and Promotion Order Definitions § 1205.320 Marketing year. Marketing year means a consecutive 12...

  14. 7 CFR 1205.320 - Marketing year.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Marketing year. 1205.320 Section 1205.320 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Research and Promotion Order Definitions § 1205.320 Marketing year. Marketing year means a consecutive 12...

  15. 7 CFR 1205.320 - Marketing year.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Marketing year. 1205.320 Section 1205.320 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Research and Promotion Order Definitions § 1205.320 Marketing year. Marketing year means a consecutive 12...

  16. 20 CFR 320.5 - Initial determinations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Initial determinations. 320.5 Section 320.5 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT... for unemployment or sickness benefits by the appropriate adjudicating office as provided by § 320.6 of...

  17. 15 CFR 904.241 - Depositions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Depositions. 904.241 Section 904.241... and Appeal Procedures Discovery § 904.241 Depositions. (a) Notice. If a motion for deposition is granted, and unless otherwise ordered by the Judge, the party taking the deposition of any person must...

  18. 15 CFR 904.241 - Depositions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Depositions. 904.241 Section 904.241... and Appeal Procedures Discovery § 904.241 Depositions. (a) Notice. If a motion for deposition is granted, and unless otherwise ordered by the Judge, the party taking the deposition of any person must...

  19. Defining the association of TMEM106B variants among frontotemporal lobar degeneration patients with GRN mutations and C9orf72 repeat expansions.

    PubMed

    Lattante, Serena; Le Ber, Isabelle; Galimberti, Daniela; Serpente, Maria; Rivaud-Péchoux, Sophie; Camuzat, Agnès; Clot, Fabienne; Fenoglio, Chiara; Scarpini, Elio; Brice, Alexis; Kabashi, Edor

    2014-11-01

    TMEM106B was identified as a risk factor for frontotemporal lobar degeneration (FTD) with TAR DNA-binding protein 43 kDa inclusions. It has been reported that variants in this gene are genetic modifiers of the disease and that this association is stronger in patients carrying a GRN mutation or a pathogenic expansion in chromosome 9 open reading frame 72 (C9orf72) gene. Here, we investigated the contribution of TMEM106B polymorphisms in cohorts of FTD and FTD with amyotrophic lateral sclerosis patients from France and Italy. Patients carrying the C9orf72 expansion (n = 145) and patients with GRN mutations (n = 76) were compared with a group of FTD patients (n = 384) negative for mutations and to a group of healthy controls (n = 552). In our cohorts, the presence of the C9orf72 expansion did not correlate with TMEM106B genotypes but the association was very strong in individuals with pathogenic GRN mutations (p = 9.54 × 10(-6)). Our data suggest that TMEM106B genotypes differ in FTD patient cohorts and strengthen the protective role of TMEM106B in GRN carriers. Further studies are needed to determine whether TMEM106B polymorphisms are associated with other genetic causes for FTD, including C9orf72 repeat expansions. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. 7 CFR 1980.320 - Interest rate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 14 2011-01-01 2011-01-01 false Interest rate. 1980.320 Section 1980.320 Agriculture... REGULATIONS (CONTINUED) GENERAL Rural Housing Loans § 1980.320 Interest rate. The interest rate must not exceed the established applicable usury rate. Loans guaranteed under this subpart must bear a fixed...

  1. 7 CFR 1980.320 - Interest rate.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 14 2012-01-01 2012-01-01 false Interest rate. 1980.320 Section 1980.320 Agriculture... REGULATIONS (CONTINUED) GENERAL Rural Housing Loans § 1980.320 Interest rate. The interest rate must not exceed the established, applicable usury rate. Loans guaranteed under this subpart must bear a fixed...

  2. 7 CFR 1980.320 - Interest rate.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 14 2014-01-01 2014-01-01 false Interest rate. 1980.320 Section 1980.320 Agriculture... REGULATIONS (CONTINUED) GENERAL Rural Housing Loans § 1980.320 Interest rate. The interest rate must not exceed the established, applicable usury rate. Loans guaranteed under this subpart must bear a fixed...

  3. 7 CFR 1980.320 - Interest rate.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 14 2013-01-01 2013-01-01 false Interest rate. 1980.320 Section 1980.320 Agriculture... REGULATIONS (CONTINUED) GENERAL Rural Housing Loans § 1980.320 Interest rate. The interest rate must not exceed the established, applicable usury rate. Loans guaranteed under this subpart must bear a fixed...

  4. 46 CFR 174.320 - Damage survival.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Damage survival. 174.320 Section 174.320 Shipping COAST... SPECIFIC VESSEL TYPES Hopper Dredges With Working Freeboard Assignments Calculations § 174.320 Damage survival. A hopper dredge survives assumed damage if it meets the following conditions: (a) The maximum...

  5. 46 CFR 174.320 - Damage survival.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Damage survival. 174.320 Section 174.320 Shipping COAST... SPECIFIC VESSEL TYPES Hopper Dredges With Working Freeboard Assignments Calculations § 174.320 Damage survival. A hopper dredge survives assumed damage if it meets the following conditions: (a) The maximum...

  6. 46 CFR 174.320 - Damage survival.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Damage survival. 174.320 Section 174.320 Shipping COAST... SPECIFIC VESSEL TYPES Hopper Dredges With Working Freeboard Assignments Calculations § 174.320 Damage survival. A hopper dredge survives assumed damage if it meets the following conditions: (a) The maximum...

  7. 32 CFR 644.320 - Floodplain management.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Floodplain management. 644.320 Section 644.320... ESTATE HANDBOOK Disposal § 644.320 Floodplain management. The requirements of Executive Order 11988, Floodplain Management, 42 FR 26951, (24 May 1977) and its implementation will be outlined in subpart H (to be...

  8. 32 CFR 644.320 - Floodplain management.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Floodplain management. 644.320 Section 644.320... ESTATE HANDBOOK Disposal § 644.320 Floodplain management. The requirements of Executive Order 11988, Floodplain Management, 42 FR 26951, (24 May 1977) and its implementation will be outlined in subpart H (to be...

  9. 32 CFR 644.320 - Floodplain management.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Floodplain management. 644.320 Section 644.320... ESTATE HANDBOOK Disposal § 644.320 Floodplain management. The requirements of Executive Order 11988, Floodplain Management, 42 FR 26951, (24 May 1977) and its implementation will be outlined in subpart H (to be...

  10. 32 CFR 644.320 - Floodplain management.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Floodplain management. 644.320 Section 644.320... ESTATE HANDBOOK Disposal § 644.320 Floodplain management. The requirements of Executive Order 11988, Floodplain Management, 42 FR 26951, (24 May 1977) and its implementation will be outlined in subpart H (to be...

  11. 46 CFR 127.320 - Storm rails.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Storm rails. 127.320 Section 127.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS CONSTRUCTION AND ARRANGEMENTS Rails and Guards § 127.320 Storm rails. Suitable storm rails must be installed in each passageway and at...

  12. 46 CFR 127.320 - Storm rails.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Storm rails. 127.320 Section 127.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS CONSTRUCTION AND ARRANGEMENTS Rails and Guards § 127.320 Storm rails. Suitable storm rails must be installed in each passageway and at...

  13. 46 CFR 127.320 - Storm rails.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Storm rails. 127.320 Section 127.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS CONSTRUCTION AND ARRANGEMENTS Rails and Guards § 127.320 Storm rails. Suitable storm rails must be installed in each passageway and at...

  14. 46 CFR 127.320 - Storm rails.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Storm rails. 127.320 Section 127.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS CONSTRUCTION AND ARRANGEMENTS Rails and Guards § 127.320 Storm rails. Suitable storm rails must be installed in each passageway and at...

  15. 46 CFR 127.320 - Storm rails.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Storm rails. 127.320 Section 127.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS CONSTRUCTION AND ARRANGEMENTS Rails and Guards § 127.320 Storm rails. Suitable storm rails must be installed in each passageway and at...

  16. Modeling of erosion and deposition patterns on C-W and W-Ta twin limiters exposed to the TEXTOR edge plasmas

    NASA Astrophysics Data System (ADS)

    Ohya, K.; Tanabe, T.; Rubel, M.; Wada, M.; Ohgo, T.; Hirai, T.; Philipps, V.; Kirschner, A.; Pospieszczyk, A.; Huber, A.; Sergienko, G.; Brezinsek, S.; Noda, N.

    2004-08-01

    The erosion and deposition patterns on tungsten and tantalum test limiters exposed to the TEXTOR deuterium plasma containing a small amount of C impurity are simulated with the modified EDDY code. At the very top of the W and Ta limiters, there occurs neither erosion nor deposition, but the erosion proceeds slowly along the surface. When approaching the edge, the surface is covered by a thick C layer, which shows a very sharp boundary similar to the observation in surface measurements. In the erosion zone, the re-deposited carbon forms a W (Ta)-C mixed layer with small C concentration. Assumptions for chemical erosion yields of ˜0.01 for W and <0.005 for Ta fit the calculated widths of the deposition zone to the experimentally determined values. Possible reasons for the difference between W and Ta are discussed.

  17. Looking south through west portion of C.W.E. Storage Shed (Bldg. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Looking south through west portion of C.W.E. Storage Shed (Bldg. 126) - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, C.W.E. Storage Shed, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  18. Oblique view looking southeast of Centralized Work Equipment (C.W.E.) Office ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Oblique view looking southeast of Centralized Work Equipment (C.W.E.) Office (Bldg. 130) - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, C.W.E. Office Building, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  19. 20 CFR 320.45 - Judicial review.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Judicial review. 320.45 Section 320.45... INITIAL DETERMINATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT AND REVIEWS OF AND APPEALS FROM SUCH DETERMINATIONS § 320.45 Judicial review. Upon being notified of a decision of the Board made (a) upon review, on...

  20. High Purity Americium-241 for Fuel Cycle R&D Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dr. Paul A. Lessing

    2011-07-01

    Previously the U.S. Department of Energy released Am-241 for various applications such as smoke detectors and Am-Be neutron sources for oil wells. At this date there is a shortage of usable, higher purity Am-241 in metal and oxide form available in the United States. Recently, the limited source of Am-241 has been from Russia with production being contracted to existing customers. The shortage has resulted in the price per gram rising dramatically over the last few years. DOE-NE currently has need for high purity Am-241 metal and oxide to fabricate fuel pellets for reactor testing in the Fuel Cycle R&Dmore » program. All the available high purity americium has been gathered from within the DOE system of laboratories. However, this is only a fraction of the projected needs of FCRD over the next 10 years. Therefore, FCR&D has proposed extraction and purification concepts to extract Am-241 from a mixed AmO2-PuO2 feedstock stored at the Savannah River Site. The most simple extraction system is based upon high temperature reduction using lanthanum metal with concurrent evaporation and condensation to produce high purity Am metal. Metallic americium has over a four order of magnitude higher vapor pressure than plutonium. Results from small-scale reduction experiments are presented. These results confirm thermodynamic predictions that at 1000 deg C metallic lanthanum reduces both PuO2 and AmO2. Faster kinetics are expected for temperatures up to about 1500 deg C.« less

  1. 7 CFR 1980.320 - Interest rate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Interest rate. 1980.320 Section 1980.320 Agriculture... REGULATIONS (CONTINUED) GENERAL Rural Housing Loans § 1980.320 Interest rate. The interest rate must not... interest rate over the life of the loan. The rate shall be agreed upon by the borrower and the Lender and...

  2. 46 CFR 182.320 - Water heaters.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Water heaters. 182.320 Section 182.320 Shipping COAST...) MACHINERY INSTALLATION Auxiliary Machinery § 182.320 Water heaters. (a) A water heater must meet the...), except that an electric water heater is also acceptable if it: (1) Has a capacity of not more than 454...

  3. 46 CFR 182.320 - Water heaters.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Water heaters. 182.320 Section 182.320 Shipping COAST...) MACHINERY INSTALLATION Auxiliary Machinery § 182.320 Water heaters. (a) A water heater must meet the...), except that an electric water heater is also acceptable if it: (1) Has a capacity of not more than 454...

  4. 29 CFR 780.320 - Nonlocal minors.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Nonlocal minors. 780.320 Section 780.320 Labor Regulations... Provisions § 780.320 Nonlocal minors. The exemption applies only to migrant or other than local hand harvest... specified minors who work for short periods of several days or weeks without returning daily to their homes...

  5. 46 CFR 182.320 - Water heaters.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Water heaters. 182.320 Section 182.320 Shipping COAST...) MACHINERY INSTALLATION Auxiliary Machinery § 182.320 Water heaters. (a) A water heater must meet the...), except that an electric water heater is also acceptable if it: (1) Has a capacity of not more than 454...

  6. 46 CFR 182.320 - Water heaters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Water heaters. 182.320 Section 182.320 Shipping COAST...) MACHINERY INSTALLATION Auxiliary Machinery § 182.320 Water heaters. (a) A water heater must meet the...), except that an electric water heater is also acceptable if it: (1) Has a capacity of not more than 454...

  7. 46 CFR 182.320 - Water heaters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Water heaters. 182.320 Section 182.320 Shipping COAST...) MACHINERY INSTALLATION Auxiliary Machinery § 182.320 Water heaters. (a) A water heater must meet the...), except that an electric water heater is also acceptable if it: (1) Has a capacity of not more than 454...

  8. 31 CFR 535.320 - Domestic bank.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Domestic bank. 535.320 Section 535.320....320 Domestic bank. (a) The term domestic bank shall mean any branch or office within the United States of any of the following which is not Iran or an Iranian entity: any bank or trust company...

  9. 46 CFR 119.320 - Water heaters.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Water heaters. 119.320 Section 119.320 Shipping COAST... Machinery § 119.320 Water heaters. (a) A water heater must meet the requirements of Parts 53 and 63 in... electric water heater is also acceptable if it: (1) Has a capacity of not more than 454 liters (120 gallons...

  10. 46 CFR 119.320 - Water heaters.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Water heaters. 119.320 Section 119.320 Shipping COAST... Machinery § 119.320 Water heaters. (a) A water heater must meet the requirements of Parts 53 and 63 in... electric water heater is also acceptable if it: (1) Has a capacity of not more than 454 liters (120 gallons...

  11. 24 CFR 91.320 - Action plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Action plan. 91.320 Section 91.320... Consolidated Plan § 91.320 Action plan. The action plan must include the following: (a) Standard Form 424; (b... outcome measures for activities included in its action plan in accordance with guidance issued by HUD. For...

  12. 24 CFR 91.320 - Action plan.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Action plan. 91.320 Section 91.320... Consolidated Plan § 91.320 Action plan. The action plan must include the following: (a) Standard Form 424; (b... outcome measures for activities included in its action plan in accordance with guidance issued by HUD. For...

  13. 46 CFR 119.320 - Water heaters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Water heaters. 119.320 Section 119.320 Shipping COAST... Machinery § 119.320 Water heaters. (a) A water heater must meet the requirements of Parts 53 and 63 in... electric water heater is also acceptable if it: (1) Has a capacity of not more than 454 liters (120 gallons...

  14. 46 CFR 119.320 - Water heaters.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Water heaters. 119.320 Section 119.320 Shipping COAST... Machinery § 119.320 Water heaters. (a) A water heater must meet the requirements of Parts 53 and 63 in... electric water heater is also acceptable if it: (1) Has a capacity of not more than 454 liters (120 gallons...

  15. 46 CFR 119.320 - Water heaters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Water heaters. 119.320 Section 119.320 Shipping COAST... Machinery § 119.320 Water heaters. (a) A water heater must meet the requirements of Parts 53 and 63 in... electric water heater is also acceptable if it: (1) Has a capacity of not more than 454 liters (120 gallons...

  16. 48 CFR 52.241-5 - Contractor's Facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Contractor's Facilities....241-5 Contractor's Facilities. As prescribed in 41.501(c)(4), insert a clause substantially the same as the following: Contractor's Facilities (FEB 1995) (a) The Contractor, at its expense, unless...

  17. 32 CFR 842.106 - Who may file a claim.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... file a claim for personal injury. (c) Executors or administrators of a decedent's estate or any other... 32 National Defense 6 2011-07-01 2011-07-01 false Who may file a claim. 842.106 Section 842.106... ADMINISTRATIVE CLAIMS Claims Under the National Guard Claims Act (32 U.S.C. 715) § 842.106 Who may file a claim...

  18. 32 CFR 842.106 - Who may file a claim.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... file a claim for personal injury. (c) Executors or administrators of a decedent's estate or any other... 32 National Defense 6 2010-07-01 2010-07-01 false Who may file a claim. 842.106 Section 842.106... ADMINISTRATIVE CLAIMS Claims Under the National Guard Claims Act (32 U.S.C. 715) § 842.106 Who may file a claim...

  19. New apparatus with high radiation energy between 320-460 nm: physical description and dermatological applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mutzhas, M.F.; Holzle, E.; Hofmann, C.

    1981-01-01

    A new apparatus (UVASUN 5000) is presented with high-radiation energy between 320 to 460 nm. The measureable energy below 320 nm was shown to be many orders of magnitude too low to produce erythema. The radiator is a specially developed source for high uv-A intensity, housing a quartz bulb with a mixture of argon, mercury and metal-halides. At a skin-target distance of 0.2 m the size of the irradiated area is 0.35 x 0.35 m, and the measured mean uv-A intensity is about 1400 W. m-2 (140 mW . cm-2). The uv-A energy in the range of 320 to 400more » nm is about 84% of the total radiation energy. Effects of very high doses of uv-A on human skin were studied. Following single uv-a applications the minimal tanning dose uv-A (MTD) and the immediate pigment darkening (IPD) dose of uv-A were established. The calculated IPD threshold time was 1.8 min at 0.2 m. Repeated exposure to this uv-A delivering system yields long lasting dark brown skin pigmentation without any clinical or histological signs of sunburn (uv-B) damage, epidermal hyperplasia or thickening of the stratum corneum. The instrument was also successfully used for photo-patch testing and reproduction of skin lesions of polymorphous light eruption. Minimal therapeutic results were seen in the phototherapy of vitiligo and inflammatory acne.« less

  20. Educational Reforms beyond Kannangara for the 21st Century: Dr. C. W. W. Kannangara Memorial Lecture

    ERIC Educational Resources Information Center

    Sedere, Mohottige Upali

    2016-01-01

    Hon C. W. W Kannanagara is truly the father of Free Education in Sri Lanka who had a vision of providing free education to all at all levels from primary to tertiary in 1944, whereas it was only in 1990, after Jometien EFA conference, the world development organization advocated at least primary education must be free for all. After 70 years of…

  1. 40 CFR 761.320 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Applicability. 761.320 Section 761.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT POLYCHLORINATED BIPHENYLS (PCBs) MANUFACTURING, PROCESSING, DISTRIBUTION IN COMMERCE, AND USE PROHIBITIONS Self...

  2. MicroRNA-320 suppresses colorectal cancer by targeting SOX4, FOXM1, and FOXQ1

    PubMed Central

    Vishnubalaji, Radhakrishnan; Hamam, Rimi; Shijun, Yue; Al-Obeed, Omar; Kassem, Moustapha; Liu, Fei-Fei; Aldahmash, Abdullah; Alajez, Nehad M.

    2016-01-01

    Colorectal cancer (CRC) is the third most common cancer causing high mortality rates world-wide. Delineating the molecular mechanisms leading to CRC development and progression, including the role of microRNAs (miRNAs), are currently being unravelled at a rapid rate. Here, we report frequent downregulation of the microRNA miR-320 family in primary CRC tissues and cell lines. Lentiviral-mediated re-expression of miR-320c (representative member of the miR-320 family) inhibited HCT116 CRC growth and migration in vitro, sensitized CRC cells to 5-Fluorouracil (5-FU), and inhibited tumor formation in SCID mice. Global gene expression analysis in CRC cells over-expressing miR-320c, combined with in silico prediction identified 84 clinically-relevant potential gene targets for miR-320 in CRC. Using a series of biochemical assays and functional validation, SOX4, FOXM1, and FOXQ1 were validated as novel gene targets for the miR-320 family. Inverse correlation between the expression of miR-320 members with SOX4, FOXM1, and FOXQ1 was observed in primary CRC patients' specimens, suggesting that these genes are likely bona fide targets for the miR-320 family. Interestingly, interrogation of the expression levels of this gene panel (SOX4, FOXM1, and FOXQ1) in The Cancer Genome Atlas (TCGA) colorectal cancer data set (319 patients) revealed significantly poor disease-free survival in patients with elevated expression of this gene panel (P-Value: 0.0058). Collectively, our data revealed a novel role for the miR-320/SOX4/FOXM1/FOXQ1 axes in promoting CRC development and progression and suggest targeting those networks as potential therapeutic strategy for CRC. PMID:27119506

  3. 40 CFR 436.241 - Specialized definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 30 2011-07-01 2011-07-01 false Specialized definitions. 436.241 Section 436.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Diatomite Subcategory § 436.241...

  4. 40 CFR 436.241 - Specialized definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Specialized definitions. 436.241 Section 436.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Diatomite Subcategory § 436.241...

  5. 40 CFR 98.241 - Reporting threshold.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Reporting threshold. 98.241 Section 98.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.241 Reporting threshold. You must report...

  6. 40 CFR 98.241 - Reporting threshold.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Reporting threshold. 98.241 Section 98.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.241 Reporting threshold. You must report...

  7. [Determination of americium-241 in urine].

    PubMed

    Shvydko, N S; Mikhaĭlova, O A; Popov, D K

    1988-01-01

    A technique has been developed for the determination of americium 241 in urine by a radiochemical purification of the nuclide from uranium (upon co-precipitation of americium 241 with calcium and lanthanum), plutonium, thorium, and polonium 210 (upon co-precipitation of these radionuclides with zirconium iodate). alpha-Radioactivity was measured either in a thick layer of the americium 241 precipitate with a nonisotope carrier or in thin-layer preparations after electrolytic precipitation of americium 241 on a cathode.

  8. 40 CFR 761.320 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Applicability. 761.320 Section 761.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT...-Implementing Alternative Extraction and Chemical Analysis Procedures for Non-liquid PCB Remediation Waste...

  9. 40 CFR 761.320 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Applicability. 761.320 Section 761.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT...-Implementing Alternative Extraction and Chemical Analysis Procedures for Non-liquid PCB Remediation Waste...

  10. 40 CFR 761.320 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Applicability. 761.320 Section 761.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT...-Implementing Alternative Extraction and Chemical Analysis Procedures for Non-liquid PCB Remediation Waste...

  11. 40 CFR 761.320 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Applicability. 761.320 Section 761.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT...-Implementing Alternative Extraction and Chemical Analysis Procedures for Non-liquid PCB Remediation Waste...

  12. STS-106 crew is welcomed home at the SLF

    NASA Technical Reports Server (NTRS)

    2000-01-01

    At the Shuttle Landing Facility, KSC Launch Director Michael Leinbach (shaking hands) greets STS-106 Pilot Scott D. Altman and Commander Terrence W. Wilcutt after their successful mission and landing. Just behind Leinbach is Jim Halsell, manager of Space Shuttle Launch Integration and former Shuttle Commander, plus other dignitaries on hand to welcome the crew home. Landing occurred on-time at 3:56:48 a.m. EDT. Atlantis and crew traveled 4.9 million miles on the 11-day, 19-hour, 11-minute STS-106 mission. During the mission to the International Space Station, the crew transferred nearly 5,000 pounds of equipment and supplies for use by the first resident crew expected to arrive in November. STs-106 was the 99th flight in the Shuttle program and the 22nd for Atlantis. STS-106 also marked the 15th nighttime landing in Shuttle history and the 23rd consecutive landing at KSC.

  13. Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets

    PubMed Central

    Satterfield, Benjamin A.; Cross, Robert W.; Fenton, Karla A.; Borisevich, Viktoriya; Agans, Krystle N.; Deer, Daniel J.; Graber, Jessica; Basler, Christopher F.; Mire, Chad E.

    2016-01-01

    ABSTRACT Nipah virus (NiV) is a highly lethal paramyxovirus that recently emerged as a causative agent of febrile encephalitis and severe respiratory disease in humans. The ferret model has emerged as the preferred small-animal model with which to study NiV disease, but much is still unknown about the viral determinants of NiV pathogenesis, including the contribution of the C protein in ferrets. Additionally, studies have yet to examine the synergistic effects of the various P gene products on pathogenesis in animal models. Using recombinant NiVs (rNiVs), we examine the sole contribution of the NiV C protein and the combined contributions of the C and W proteins in the ferret model of NiV pathogenesis. We show that an rNiV void of C expression resulted in 100% mortality, though with limited respiratory disease, like our previously reported rNiV void of W expression; this finding is in stark contrast to the attenuated phenotype observed in previous hamster studies utilizing rNiVs void of C expression. We also observed that an rNiV void of both C and W expression resulted in limited respiratory disease; however, there was severe neurological disease leading to 60% mortality, and the surviving ferrets demonstrated sequelae similar to those for human survivors of NiV encephalitis. IMPORTANCE Nipah virus (NiV) is a human pathogen capable of causing lethal respiratory and neurological disease. Many human survivors have long-lasting neurological impairment. Using a ferret model, this study demonstrated the roles of the NiV C and W proteins in pathogenesis, where lack of either the C or the W protein independently decreased the severity of clinical respiratory disease but did not decrease lethality. Abolishing both C and W expression, however, dramatically decreased the severity of respiratory disease and the level of destruction of splenic germinal centers. These ferrets still suffered severe neurological disease: 60% succumbed to disease, and the survivors experienced

  14. 32 CFR 241.11 - Numerical limitation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Numerical limitation. 241.11 Section 241.11 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.11 Numerical...

  15. 32 CFR 241.11 - Numerical limitation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Numerical limitation. 241.11 Section 241.11 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.11 Numerical...

  16. 32 CFR 241.11 - Numerical limitation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Numerical limitation. 241.11 Section 241.11 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.11 Numerical...

  17. The Climate Change Consortium of Wales (C3W)

    NASA Astrophysics Data System (ADS)

    Hendry, K. R.; Reis, J.; Hall, I. R.

    2011-12-01

    In response to the complexity and multidisciplinary nature of climate change research, the Climate Change Consortium of Wales (C3W) was formed in 2009 by the Welsh universities of Aberystwyth, Bangor, Cardiff and Swansea. Initially funded by Welsh Government, through the Higher Education Funding Council for Wales, the Countryside Council for Wales and the universities, C3W aims to bring together climate change researchers from a wide range of disciplines to explore scientific and sociological drivers, impacts and implications at local, national and international scale. The specific aims are to i) improve our fundamental understanding of the causes, nature, timing and consequences of climate change on Planet Earth's environment and on humanity, and ii) to reconfigure climate research in Wales as a recognisable centre of excellence on the world stage. In addition to improving the infrastructure for climate change research, we aim to improve communication, networking, collaborative research, and multidisciplinary data assimilation within and between the Welsh universities, and other UK and international institutions. Furthermore, C3W aims to apply its research by actively contributing towards national policy development, business development and formal and informal education activities within and beyond Wales.

  18. Detail of C.W.E. Storage Shed (Bldg. 126) monorails and safety ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of C.W.E. Storage Shed (Bldg. 126) monorails and safety sign for track workers. Machine Shop (Bldg. 134) is in the background - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, C.W.E. Storage Shed, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  19. 10 CFR 600.241 - Financial reporting.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Financial reporting. 600.241 Section 600.241 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Uniform Administrative....241 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5) of this...

  20. 32 CFR 241.11 - Numerical limitation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Numerical limitation. 241.11 Section 241.11 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED...) § 241.11 Numerical limitation. The ITEP Pilot is an opportunity for the exchange of knowledge...

  1. 10 CFR 600.241 - Financial reporting.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Financial reporting. 600.241 Section 600.241 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Uniform Administrative....241 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5) of this...

  2. Case study: three acute 241Am inhalation exposures with DTPA therapy.

    PubMed

    Carbaugh, Eugene H; Lynch, Timothy P; Cannon, Curt N; Lewis, Loren L

    2010-10-01

    Three workers incurred inhalation exposures to Am oxide as a result of waste sorting and compaction activities. The exposure magnitudes were not fully recognized until the following day when an in-vivo lung count identified a significant lung deposition of Am in a male worker, and DTPA chelation therapy was initiated. Two additional workers (one female and one male) were then identified as sufficiently exposed to also warrant therapy. In-vivo bioassay measurements were performed over the ensuing 6 mo to quantify the 241Am activity in the lungs, liver, and skeleton. Urine and fecal samples were collected and showed readily detectable 241Am. Clinical lab tests and medical evaluations all showed normal results. There were no significant adverse clinical health effects from the therapy. The estimated 241Am inhalation intakes for the three workers were 1,800 Bq, 630 Bq, and 150 Bq. Lung retention showed somewhat longer pulmonary clearance half-times than standard inhalation class W or absorption Type M assumptions. The three subjects underwent slightly different therapy regimens, with therapy effectiveness factors (defined as the ratio of the reference doses without therapy relative to the final assessed doses) of 4.5, 1.9, and 1.7, respectively.

  3. 12 CFR 335.241 - Unlisted trading.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Unlisted trading. 335.241 Section 335.241 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY SECURITIES OF NONMEMBER INSURED BANKS § 335.241 Unlisted trading. The provisions of the applicable and...

  4. 42 CFR 413.241 - Pharmacy arrangements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 2 2012-10-01 2012-10-01 false Pharmacy arrangements. 413.241 Section 413.241... Disease (ESRD) Services and Organ Procurement Costs § 413.241 Pharmacy arrangements. Effective January 1, 2011, an ESRD facility that enters into an arrangement with a pharmacy to furnish renal dialysis...

  5. 42 CFR 413.241 - Pharmacy arrangements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 2 2014-10-01 2014-10-01 false Pharmacy arrangements. 413.241 Section 413.241... Disease (ESRD) Services and Organ Procurement Costs § 413.241 Pharmacy arrangements. Effective January 1, 2011, an ESRD facility that enters into an arrangement with a pharmacy to furnish renal dialysis...

  6. 42 CFR 413.241 - Pharmacy arrangements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 2 2013-10-01 2013-10-01 false Pharmacy arrangements. 413.241 Section 413.241... Disease (ESRD) Services and Organ Procurement Costs § 413.241 Pharmacy arrangements. Effective January 1, 2011, an ESRD facility that enters into an arrangement with a pharmacy to furnish renal dialysis...

  7. 16 CFR 24.1 - Deception (general).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Deception (general). 24.1 Section 24.1 Commercial Practices FEDERAL TRADE COMMISSION GUIDES AND TRADE PRACTICE RULES GUIDES FOR SELECT LEATHER AND IMITATION LEATHER PRODUCTS § 24.1 Deception (general). It is unfair or deceptive to misrepresent, directly...

  8. 28 CFR 2.41 - Travel approval.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Travel approval. 2.41 Section 2.41..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.41 Travel approval. (a) The probation officer may approve travel outside the district without approval of the...

  9. 12 CFR 335.241 - Unlisted trading.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Unlisted trading. 335.241 Section 335.241 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY SECURITIES OF NONMEMBER INSURED BANKS § 335.241 Unlisted trading. The provisions of the applicable and...

  10. 12 CFR 335.241 - Unlisted trading.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Unlisted trading. 335.241 Section 335.241 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY SECURITIES OF NONMEMBER INSURED BANKS § 335.241 Unlisted trading. The provisions of the applicable and...

  11. 12 CFR 335.241 - Unlisted trading.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 5 2012-01-01 2012-01-01 false Unlisted trading. 335.241 Section 335.241 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY SECURITIES OF NONMEMBER INSURED BANKS § 335.241 Unlisted trading. The provisions of the applicable and...

  12. 12 CFR 335.241 - Unlisted trading.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Unlisted trading. 335.241 Section 335.241 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY SECURITIES OF NONMEMBER INSURED BANKS § 335.241 Unlisted trading. The provisions of the applicable and...

  13. Behavior of W-SiC/SiC dual layer tiles under LHD plasma exposure

    NASA Astrophysics Data System (ADS)

    Mohrez, Waleed A.; Kishimoto, Hirotatsu; Kohno, Yutaka; Hirotaki, S.; Kohyama, Akira

    2013-11-01

    Towards the early realization of fusion power reactors, high performance first wall and plasma facing components (PFCs) are essentially required. As one of the biggest challenges for this, high heat flux component (HHFC) design and R & D has been emphasized. This report provides the high performance HHFC materials R & D status and the first plasma exposure test result from large helical device (LHD). W-SiC/SiC dual layer tiles (hereafter, W-SiC/SiC) were developed by applied NITE process. This is the realistic concept of tungsten armor with ceramic composite substrates for fusion power reactors. The dual layer tiles were fabricated and tested their survival under the LHD divertor plasma exposure (Nominally 10 MW/m2 maximum heat load for 6 s operation cycle). The microstructure evolution, including crack and pore formation, was analyzed, besides the behavior of bonding layer between tungsten and SiC/SiC was evaluated by C-scanning images of ultrasonic method and Electron probe Micro-analyzer (EPMA). Thermal analysis was conducted by finite element method, where ANSYS code release 13.0 was used.

  14. 14 CFR 27.241 - Ground resonance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ground resonance. 27.241 Section 27.241... STANDARDS: NORMAL CATEGORY ROTORCRAFT Flight Ground and Water Handling Characteristics § 27.241 Ground resonance. The rotorcraft may have no dangerous tendency to oscillate on the ground with the rotor turning...

  15. 14 CFR 29.241 - Ground resonance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ground resonance. 29.241 Section 29.241... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight Ground and Water Handling Characteristics § 29.241 Ground resonance. The rotorcraft may have no dangerous tendency to oscillate on the ground with the rotor turning...

  16. 14 CFR 27.241 - Ground resonance.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ground resonance. 27.241 Section 27.241... STANDARDS: NORMAL CATEGORY ROTORCRAFT Flight Ground and Water Handling Characteristics § 27.241 Ground resonance. The rotorcraft may have no dangerous tendency to oscillate on the ground with the rotor turning...

  17. 14 CFR 29.241 - Ground resonance.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ground resonance. 29.241 Section 29.241... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight Ground and Water Handling Characteristics § 29.241 Ground resonance. The rotorcraft may have no dangerous tendency to oscillate on the ground with the rotor turning...

  18. 40 CFR 98.241 - Reporting threshold.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Reporting threshold. 98.241 Section 98.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.241 Reporting threshold. You must report GHG emissions under this subpart if your...

  19. 40 CFR 98.241 - Reporting threshold.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Reporting threshold. 98.241 Section 98.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.241 Reporting threshold. You must report GHG emissions under this subpart if your...

  20. 40 CFR 98.241 - Reporting threshold.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Reporting threshold. 98.241 Section 98.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.241 Reporting threshold. You must report GHG emissions under this subpart if your...

  1. 47 CFR 27.310-27.320 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false [Reserved] 27.310-27.320 Section 27.310-27.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Application, Licensing, and Processing Rules for WCS §§ 27.310-27.320 [Reserved] ...

  2. 47 CFR 27.310-27.320 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false [Reserved] 27.310-27.320 Section 27.310-27.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Application, Licensing, and Processing Rules for WCS §§ 27.310-27.320 [Reserved] ...

  3. 46 CFR 132.320 - Helicopter-landing decks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Helicopter-landing decks. 132.320 Section 132.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS FIRE-PROTECTION EQUIPMENT Miscellaneous § 132.320 Helicopter-landing decks. Each vessel with a helicopter-landing deck must...

  4. 46 CFR 132.320 - Helicopter-landing decks.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Helicopter-landing decks. 132.320 Section 132.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS FIRE-PROTECTION EQUIPMENT Miscellaneous § 132.320 Helicopter-landing decks. Each vessel with a helicopter-landing deck must...

  5. 46 CFR 132.320 - Helicopter-landing decks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Helicopter-landing decks. 132.320 Section 132.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS FIRE-PROTECTION EQUIPMENT Miscellaneous § 132.320 Helicopter-landing decks. Each vessel with a helicopter-landing deck must...

  6. 46 CFR 132.320 - Helicopter-landing decks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Helicopter-landing decks. 132.320 Section 132.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS FIRE-PROTECTION EQUIPMENT Miscellaneous § 132.320 Helicopter-landing decks. Each vessel with a helicopter-landing deck must...

  7. 46 CFR 132.320 - Helicopter-landing decks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Helicopter-landing decks. 132.320 Section 132.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS FIRE-PROTECTION EQUIPMENT Miscellaneous § 132.320 Helicopter-landing decks. Each vessel with a helicopter-landing deck must...

  8. 46 CFR 129.320 - Generators and motors.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Generators and motors. 129.320 Section 129.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS Power Sources and Distribution Systems § 129.320 Generators and motors. (a) Each generator and...

  9. 46 CFR 129.320 - Generators and motors.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Generators and motors. 129.320 Section 129.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS Power Sources and Distribution Systems § 129.320 Generators and motors. (a) Each generator and...

  10. 46 CFR 129.320 - Generators and motors.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Generators and motors. 129.320 Section 129.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS Power Sources and Distribution Systems § 129.320 Generators and motors. (a) Each generator and...

  11. Looking south through east portion of Centralized Work Equipment (C.W.E.) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Looking south through east portion of Centralized Work Equipment (C.W.E.) Storage Shed (Bldg. 126). Note overhead monorails for material-handling hoists. This shed stored track maintenance materials - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, C.W.E. Storage Shed, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  12. 2 CFR 25.320 - Entity.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Entity. 25.320 Section 25.320 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS Reserved UNIVERSAL IDENTIFIER AND CENTRAL CONTRACTOR...

  13. 2 CFR 25.320 - Entity.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Entity. 25.320 Section 25.320 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS PRE-AWARD RESPONSIBILITIES UNIVERSAL IDENTIFIER AND CENTRAL...

  14. 2 CFR 25.320 - Entity.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Entity. 25.320 Section 25.320 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS PRE-AWARD RESPONSIBILITIES UNIVERSAL IDENTIFIER AND CENTRAL...

  15. 32 CFR 241.5 - Written agreements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Written agreements. 241.5 Section 241.5 National... PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.5 Written agreements. (a... to be assigned to ITEP must sign a three-party agreement. Prior to the agreement being signed the...

  16. 32 CFR 241.5 - Written agreements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Written agreements. 241.5 Section 241.5 National... PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.5 Written agreements. (a... agreement. Prior to the agreement being signed the relevant legal office for the DoD Component shall review...

  17. 46 CFR 183.320 - Generators and motors.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Generators and motors. 183.320 Section 183.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.320 Generators and motors. (a) Each...

  18. 46 CFR 183.320 - Generators and motors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Generators and motors. 183.320 Section 183.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.320 Generators and motors. (a) Each...

  19. 46 CFR 183.320 - Generators and motors.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Generators and motors. 183.320 Section 183.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.320 Generators and motors. (a) Each...

  20. 46 CFR 183.320 - Generators and motors.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Generators and motors. 183.320 Section 183.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.320 Generators and motors. (a) Each...

  1. 46 CFR 183.320 - Generators and motors.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Generators and motors. 183.320 Section 183.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.320 Generators and motors. (a) Each...

  2. The HCM-linked W792R mutation in cardiac myosin-binding protein C reduces C6 FnIII domain stability.

    PubMed

    Smelter, Dan F; de Lange, Willem J; Cai, Wenxuan; Ge, Ying; Ralphe, J Carter

    2018-06-01

    Cardiac myosin-binding protein C (cMyBP-C) is a functional sarcomeric protein that regulates contractility in response to contractile demand, and many mutations in cMyBP-C lead to hypertrophic cardiomyopathy (HCM). To gain insight into the effects of disease-causing cMyBP-C missense mutations on contractile function, we expressed the pathogenic W792R mutation (substitution of a highly conserved tryptophan residue by an arginine residue at position 792) in mouse cardiomyocytes lacking endogenous cMyBP-C and studied the functional effects using three-dimensional engineered cardiac tissue constructs (mECTs). Based on complete conservation of tryptophan at this location in fibronectin type II (FnIII) domains, we hypothesized that the W792R mutation affects folding of the C6 FnIII domain, destabilizing the mutant protein. Adenoviral transduction of wild-type (WT) and W792R cDNA achieved equivalent mRNA transcript abundance, but not equivalent protein levels, with W792R compared with WT controls. mECTs expressing W792R demonstrated abnormal contractile kinetics compared with WT mECTs that were nearly identical to cMyBP-C-deficient mECTs. We studied whether common pathways of protein degradation were responsible for the rapid degradation of W792R cMyBP-C. Inhibition of both ubiquitin-proteasome and lysosomal degradation pathways failed to increase full-length mutant protein abundance to WT equivalence, suggesting rapid cytosolic degradation. Bacterial expression of WT and W792R protein fragments demonstrated decreased mutant stability with altered thermal denaturation and increased susceptibility to trypsin digestion. These data suggest that the W792R mutation destabilizes the C6 FnIII domain of cMyBP-C, resulting in decreased full-length protein expression. This study highlights the vulnerability of FnIII-like domains to mutations that alter domain stability and further indicates that missense mutations in cMyBP-C can cause disease through a mechanism of

  3. Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets.

    PubMed

    Satterfield, Benjamin A; Cross, Robert W; Fenton, Karla A; Borisevich, Viktoriya; Agans, Krystle N; Deer, Daniel J; Graber, Jessica; Basler, Christopher F; Geisbert, Thomas W; Mire, Chad E

    2016-07-15

    Nipah virus (NiV) is a highly lethal paramyxovirus that recently emerged as a causative agent of febrile encephalitis and severe respiratory disease in humans. The ferret model has emerged as the preferred small-animal model with which to study NiV disease, but much is still unknown about the viral determinants of NiV pathogenesis, including the contribution of the C protein in ferrets. Additionally, studies have yet to examine the synergistic effects of the various P gene products on pathogenesis in animal models. Using recombinant NiVs (rNiVs), we examine the sole contribution of the NiV C protein and the combined contributions of the C and W proteins in the ferret model of NiV pathogenesis. We show that an rNiV void of C expression resulted in 100% mortality, though with limited respiratory disease, like our previously reported rNiV void of W expression; this finding is in stark contrast to the attenuated phenotype observed in previous hamster studies utilizing rNiVs void of C expression. We also observed that an rNiV void of both C and W expression resulted in limited respiratory disease; however, there was severe neurological disease leading to 60% mortality, and the surviving ferrets demonstrated sequelae similar to those for human survivors of NiV encephalitis. Nipah virus (NiV) is a human pathogen capable of causing lethal respiratory and neurological disease. Many human survivors have long-lasting neurological impairment. Using a ferret model, this study demonstrated the roles of the NiV C and W proteins in pathogenesis, where lack of either the C or the W protein independently decreased the severity of clinical respiratory disease but did not decrease lethality. Abolishing both C and W expression, however, dramatically decreased the severity of respiratory disease and the level of destruction of splenic germinal centers. These ferrets still suffered severe neurological disease: 60% succumbed to disease, and the survivors experienced long-term neurological

  4. Fabrication of low thermal expansion SiC/ZrW2O8 porous ceramics

    NASA Astrophysics Data System (ADS)

    Poowancum, A.; Matsumaru, K.; Juárez-Ramírez, I.; Torres-Martínez, L. M.; Fu, Z. Y.; Lee, S. W.; Ishizaki, K.

    2011-03-01

    Low or zero thermal expansion porous ceramics are required for several applications. In this work near zero thermal expansion porous ceramics were fabricated by using SiC and ZrW2O8 as positive and negative thermal expansion materials, respectively, bonded by soda lime glass. The mixture of SiC, ZrW2O8 and soda lime glass was sintered by Pulsed Electric Current Sintering (PECS, or sometimes called Spark Plasma Sintering, SPS) at 700 °C. Sintered samples with ZrW2O8 particle size smaller than 25 μm have high thermal expansion coefficient, because ZrW2O8 has the reaction with soda lime glass to form Na2ZrW3O12 during sintering process. The reaction between soda lime glass and ZrW2O8 is reduced by increasing particle size of ZrW2O8. Sintered sample with ZrW2O8 particle size 45-90 μm shows near zero thermal expansion.

  5. Detail of C.W.E. Storage Shed (Bldg. 126) monorail switches. Workers ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of C.W.E. Storage Shed (Bldg. 126) monorail switches. Workers pulled the chains at right to align the switches. Workers also pulled the hoists, loaded or unloaded, along the monorail tracks - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, C.W.E. Storage Shed, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  6. 39 CFR 241.1 - Post offices.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Post offices. 241.1 Section 241.1 Postal Service... DISCONTINUANCE § 241.1 Post offices. (a) Establishment. See § 113.1 of this chapter. (b) Classification. As of July 1 each year, post offices are classified by the Postmaster General based on the allowable postal...

  7. 46 CFR 129.320 - Generators and motors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Generators and motors. 129.320 Section 129.320 Shipping... INSTALLATIONS Power Sources and Distribution Systems § 129.320 Generators and motors. (a) Each generator and... contact with low-lying vapors. (b) Each generator and motor must be designed for an ambient temperature of...

  8. 25 CFR 20.320 - What is TWEP?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What is TWEP? 20.320 Section 20.320 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Direct Assistance Tribal Work Experience Program (twep) § 20.320 What is TWEP? TWEP is a program...

  9. Existence of c-Kit negative cells with ultrastructural features of interstitial cells of Cajal in the subserosal layer of the W/W(v) mutant mouse colon.

    PubMed

    Tamada, Hiromi; Kiyama, Hiroshi

    2015-01-01

    Interstitial cells of Cajal (ICC) are mesenchymal cells that are distributed along the gastrointestinal tract and function as pacemaker cells or intermediary cells between nerves and smooth muscle cells. ICC express a receptor tyrosine kinase c-Kit, which is an established marker for ICC. The c-kit gene is allelic with the murine white-spotting locus (W), and some ICC subsets were reported to be missing in heterozygous mutant W/W(v) mice carrying W and W(v) mutated alleles. In this study, the characterization of interstitial cells in the subserosal layer of W/W(v) mice was analyzed by immunohistochemistry and electron microscopy. In the proximal and distal colon of W/W(v) mutant mice, no c-Kit-positive cells were detected in the subserosal layer by immunohistochemistry. By electron microscopy, the interstitial cells, which were characterized by the existence of caveolae, abundant mitochondria and gap junctions, were observed in the W/W(v) mutant colon. The morphological characteristics were comparable to those of the multipolar c-Kit positive ICC seen in the subserosa of proximal and distal colon of wild-type mice. Fibroblasts were also located in the same layers, but the morphology of the fibroblasts was distinguishable from that of ICC in wild type mice or of ICC-like cells in W/W(v) mutant mice. Collectively, it is concluded that c-Kit-negative interstitial cells showing a typical ICC ultrastructure exist in the proximal and distal colon of W/W(v) mutant mice.

  10. Commander Wilcutt poses for a photo on Zvezda during STS-106

    NASA Image and Video Library

    2000-09-13

    S106-E-5192 (13 September 2000) --- Astronaut Terrence W. Wilcutt, mission commander, displays a pleasant countenance onboard the International Space Station as the crew nears the halfway point of docked operations with the International Space Station. In all the crew will have 189 hours, 40 minutes of planned Atlantis-ISS docked time. For most of the remainder of the time until the Atlantis undocks from the ISS, the STS-106 astronauts and cosmonauts continue electrical work and transfer activities.

  11. STS-106 Crew Activity Report/Flight Day 8 Highlights

    NASA Technical Reports Server (NTRS)

    2000-01-01

    On this eighth day of the STS-106 Atlantis mission, the flight crew, Commander Terrence W. Wilcutt, Pilot Scott T. Altman, and Mission Specialists Daniel C. Burbank, Edward T. Lu, Richard A. Mastracchio, Yuri Ivanovich Malenchenko, and Boris V. Morukov move into the second half of preparing the International Space Station (ISS) for its first resident crew. Lu and Malenchenko are seen installing the power converters in the Zvezda module and components of the primary oxygen generation system. Mastracchio and Wilcutt moves supplies and logistics from the payload of Atlantis to the ISS. Wilcutt and Altman participate in several interviews and the crew wishes the Olympiads in Sydney good luck in their endeavors. Scenes also include external views of the ISS and images of Earth, including Sydney, Australia.

  12. 40 CFR 60.241 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false Definitions. 60.241 Section 60.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for the Phosphate Fertilizer Industry...

  13. 40 CFR 60.241 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Definitions. 60.241 Section 60.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for the Phosphate Fertilizer Industry...

  14. 40 CFR 60.241 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false Definitions. 60.241 Section 60.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for the Phosphate Fertilizer Industry...

  15. 48 CFR 241.202 - Procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Procedures. 241.202 Section 241.202 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... connection charge. (ii) Termination liability. Use when an obligation is necessary to secure the required...

  16. 48 CFR 241.202 - Procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Procedures. 241.202 Section 241.202 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... connection charge. (ii) Termination liability. Use when an obligation is necessary to secure the required...

  17. 48 CFR 241.202 - Procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Procedures. 241.202 Section 241.202 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... connection charge. (ii) Termination liability. Use when an obligation is necessary to secure the required...

  18. 48 CFR 241.202 - Procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Procedures. 241.202 Section 241.202 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... connection charge. (ii) Termination liability. Use when an obligation is necessary to secure the required...

  19. 48 CFR 241.202 - Procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Procedures. 241.202 Section 241.202 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... connection charge. (ii) Termination liability. Use when an obligation is necessary to secure the required...

  20. Overview of C-2U FRC Experimental Program and Plans for C-2W

    NASA Astrophysics Data System (ADS)

    Gota, H.; Binderbauer, M. W.; Tajima, T.; Putvinski, S.; Tuszewski, M.; Dettrick, S.; Korepanov, S.; Smirnov, A.; Thompson, M. C.; Yang, X.; Cappello, M.; Ivanov, A. A.; TAE Team

    2016-10-01

    Tri Alpha Energy's experimental program has been focused on a demonstration of reliable field-reversed configuration (FRC) formation and sustainment, driven by fast ions via high-power neutral-beam (NB) injection. The world's largest compact-toroid experimental devices, C-2 and C-2U, have successfully produced a well-stabilized, sustainable FRC plasma state with NB injection (input power, PNB 10 + MW; 15 keV hydrogen) and end-on coaxial plasma guns. Remarkable improvements in confinement and stability of FRC plasmas have led to further improved fast-ion build up; thereby, an advanced beam-driven FRC state has been produced and sustained for up to 5 + ms (longer than all characteristic system time scales), only limited by hardware and electric supply constraints such as NB and plasma-gun power supplies. To further improve the FRC performance the C-2U device is being replaced by C-2W featuring higher injected NB power, longer pulse duration as well as enhanced edge-biasing systems and substantially upgraded divertors. Main C-2U experimental results and key features of C-2W will be presented. Tri Alpha Energy, Inc.

  1. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.320 Provider alert gateway requirements. This section specifies the functions...

  2. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.320 Provider alert gateway requirements. This section specifies the functions...

  3. Mechanistic Basis Of Calmodulin Mediated Estrogen Receptor Alpha Activation and Antiestrogen Resistance

    DTIC Science & Technology

    2010-06-01

    for solubility (Figure 5). We call this protein Trx -ERA241-320. We also produced a similar protein construct, but with only residues 241-273 of...ERa, as a “control” (Figure 5). We call this protein Trx -ERA241-273. Because CaM binds tightly to the N-terminal extended ligand binding domain of...ERa (residues 286- 552, see above), we hypothesized that Trx - ERA241-320 would bind tightly to CaM, but that Trx -ERA241-273 would not. The genetic

  4. 50 CFR 660.320 - Open access fishery-crossover provisions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Open access fishery-crossover provisions... West Coast Groundfish-Open Access Fisheries § 660.320 Open access fishery—crossover provisions. (a) Operating in both limited entry and open access fisheries. See provisions at § 660.60, subpart C. (b...

  5. 50 CFR 660.320 - Open access fishery-crossover provisions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Open access fishery-crossover provisions... West Coast Groundfish-Open Access Fisheries § 660.320 Open access fishery—crossover provisions. (a) Operating in both limited entry and open access fisheries. See provisions at § 660.60, subpart C. (b...

  6. Analytical interatomic potential for modeling nonequilibrium processes in the W-C-H system

    NASA Astrophysics Data System (ADS)

    Juslin, N.; Erhart, P.; Träskelin, P.; Nord, J.; Henriksson, K. O. E.; Nordlund, K.; Salonen, E.; Albe, K.

    2005-12-01

    A reactive interatomic potential based on an analytical bond-order scheme is developed for the ternary system W-C-H. The model combines Brenner's hydrocarbon potential with parameter sets for W-W, W-C, and W-H interactions and is adjusted to materials properties of reference structures with different local atomic coordinations including tungsten carbide, W-H molecules, as well as H dissolved in bulk W. The potential has been tested in various scenarios, such as surface, defect, and melting properties, none of which were considered in the fitting. The intended area of application is simulations of hydrogen and hydrocarbon interactions with tungsten, which have a crucial role in fusion reactor plasma-wall interactions. Furthermore, this study shows that the angular-dependent bond-order scheme can be extended to second nearest-neighbor interactions, which are relevant in body-centered-cubic metals. Moreover, it provides a possibly general route for modeling metal carbides.

  7. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.320 Provider alert gateway requirements. This section specifies the functions...

  8. 40 CFR 158.320 - Product identity and composition.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Product identity and composition. 158.320 Section 158.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.320 Product identity and composition...

  9. 40 CFR 158.320 - Product identity and composition.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Product identity and composition. 158.320 Section 158.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.320 Product identity and composition...

  10. 40 CFR 158.320 - Product identity and composition.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Product identity and composition. 158.320 Section 158.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.320 Product identity and composition...

  11. 40 CFR 158.320 - Product identity and composition.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Product identity and composition. 158.320 Section 158.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.320 Product identity and composition...

  12. 40 CFR 158.320 - Product identity and composition.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Product identity and composition. 158.320 Section 158.320 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.320 Product identity and composition...

  13. 10 CFR 431.241 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Purpose and scope. 431.241 Section 431.241 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Unit Heaters § 431.241 Purpose and scope. This subpart contains energy conservation requirements...

  14. 14 CFR 121.241 - Oil system drains.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Oil system drains. 121.241 Section 121.241..., FLAG, AND SUPPLEMENTAL OPERATIONS Special Airworthiness Requirements § 121.241 Oil system drains... position, must be provided to allow safe drainage of the entire oil system. ...

  15. 14 CFR 121.241 - Oil system drains.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Oil system drains. 121.241 Section 121.241..., FLAG, AND SUPPLEMENTAL OPERATIONS Special Airworthiness Requirements § 121.241 Oil system drains... position, must be provided to allow safe drainage of the entire oil system. ...

  16. 14 CFR 121.241 - Oil system drains.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Oil system drains. 121.241 Section 121.241..., FLAG, AND SUPPLEMENTAL OPERATIONS Special Airworthiness Requirements § 121.241 Oil system drains... position, must be provided to allow safe drainage of the entire oil system. ...

  17. Tank Waste Retrieval Lessons Learned at the Hanford Site

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dodd, R.A.

    EPA approval of an exception to the waste retrieval criteria for a specific tank. Tank waste retrieval has been conducted at the Hanford Site over the last few decades using a method referred to as Past Practice Hydraulic Sluicing. Past Practice Hydraulic Sluicing employs large volumes of DST supernatant and water to dislodge, dissolve, mobilize, and retrieve tank waste. Concern over the leak integrity of SSTs resulted in the need for tank waste retrieval methods capable of using smaller volumes of liquid in a more controlled manner. Retrieval of SST waste in accordance with HFFACO requirements was initiated at the Hanford Site in April 2003. New and innovative tank waste retrieval methods that minimize and control the use of liquids are being implemented for the first time. These tank waste retrieval methods replace Past Practice Hydraulic Sluicing and employ modified sluicing, vacuum retrieval, and in-tank vehicle techniques. Waste retrieval has been completed in seven Hanford Site SSTs (C-106, C-103, C-201, C-202, C-203, C-204, and S-112) in accordance with HFFACO requirements. Three additional tanks are currently in the process of being retrieved (C-108, C-109 and S-102) Preparation for retrieval of two additional SSTs (C-104 and C-110) is ongoing with retrieval operations forecasted to start in calendar year 2008. Tank C-106 was retrieved to a residual waste volume of 470 ft{sup 3} using oxalic acid dissolution and modified sluicing. An Appendix H exception request for Tank C-106 is undergoing review. Tank C-103 was retrieved to a residual volume of 351 ft{sup 3} using a modified sluicing technology. This approach was successful at reaching the TPA limits for this tank of less than 360 ft{sup 3}and the limits of the technology. Tanks C-201, C-202, C-203, and C-204 are smaller (55,000 gallon) tanks and waste removal was completed in accordance with HFFACO requirements using a vacuum retrieval system. Residual waste volumes in each of these four tanks were less

  18. 42 CFR 24.1 - Establishment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Establishment. 24.1 Section 24.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH... Research Service (SBRS) consisting of members the maximum number of which is prescribed by law. ...

  19. High Temperature Characteristics of Pt/TaSi2/Pt/W and Pt/Ti/W Diffusion Barrier Systems for Ohmic Contacts to 4H-SiC

    NASA Technical Reports Server (NTRS)

    Okojie, Robert S.; Lukco, Dorothy

    2017-01-01

    The degradation of ohmic contacts to 4H-SiC pressure sensors over time at high temperature is primarily due to two failure mechanisms: migrating bond pad Au and atmospheric O toward the ohmic contact SiC interface and the inter-metallic mixing between diffusion barrier systems (DBS) and the underlying ohmic contact metallization. We investigated the effectiveness of Pt/TaSi2/Pt/W (DBS-A) and Pt/Ti/W (DBS-B) in preventing Au and O diffusion through the underlying binary Ti/W or alloyed W50:Ni50 ohmic contacts to 4H-SiC and the DBS ohmic contact intermixing at temperature up to 700 C.

  20. 48 CFR 252.241-7001 - Government access.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Government access. 252.241... Clauses 252.241-7001 Government access. As prescribed in 241.501-70(b), use the following clause: Government Access (DEC 1991) Authorized representatives of the Government may have access to the Contractor's...

  1. 48 CFR 252.241-7001 - Government access.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Government access. 252.241... Clauses 252.241-7001 Government access. As prescribed in 241.501-70(b), use the following clause: Government Access (DEC 1991) Authorized representatives of the Government may have access to the Contractor's...

  2. 48 CFR 252.241-7001 - Government access.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Government access. 252.241... Clauses 252.241-7001 Government access. As prescribed in 241.501-70(b), use the following clause: Government Access (DEC 1991) Authorized representatives of the Government may have access to the Contractor's...

  3. 48 CFR 252.241-7001 - Government access.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Government access. 252.241... Clauses 252.241-7001 Government access. As prescribed in 241.501-70(b), use the following clause: Government Access (DEC 1991) Authorized representatives of the Government may have access to the Contractor's...

  4. 48 CFR 252.241-7001 - Government access.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Government access. 252.241... Clauses 252.241-7001 Government access. As prescribed in 241.501-70(b), use the following clause: Government Access (DEC 1991) Authorized representatives of the Government may have access to the Contractor's...

  5. 32 CFR 320.4 - Procedures for requesting information.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Procedures for requesting information. 320.4 Section 320.4 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.4 Procedures for...

  6. 32 CFR 320.5 - Disclosure of requested information.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Disclosure of requested information. 320.5 Section 320.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.5 Disclosure of...

  7. 32 CFR 320.5 - Disclosure of requested information.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Disclosure of requested information. 320.5 Section 320.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.5 Disclosure of...

  8. 32 CFR 320.4 - Procedures for requesting information.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Procedures for requesting information. 320.4 Section 320.4 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.4 Procedures for...

  9. 32 CFR 320.4 - Procedures for requesting information.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Procedures for requesting information. 320.4 Section 320.4 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.4 Procedures for...

  10. 32 CFR 320.5 - Disclosure of requested information.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Disclosure of requested information. 320.5 Section 320.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL GEOSPATIAL-INTELLIGENCE AGENCY (NGA) PRIVACY § 320.5 Disclosure of...

  11. 14 CFR 21.320 - Changes in quality system.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Changes in quality system. 21.320 Section 21.320 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS Approval of Materials, Parts, Processes, and Appliances § 21.320...

  12. C. albicans growth, transition, biofilm formation, and gene expression modulation by antimicrobial decapeptide KSL-W

    PubMed Central

    2013-01-01

    Background Antimicrobial peptides have been the focus of much research over the last decade because of their effectiveness and broad-spectrum activity against microbial pathogens. These peptides also participate in inflammation and the innate host defense system by modulating the immune function that promotes immune cell adhesion and migration as well as the respiratory burst, which makes them even more attractive as therapeutic agents. This has led to the synthesis of various antimicrobial peptides, including KSL-W (KKVVFWVKFK-NH2), for potential clinical use. Because this peptide displays antimicrobial activity against bacteria, we sought to determine its antifungal effect on C. albicans. Growth, hyphal form, biofilm formation, and degradation were thus examined along with EFG1, NRG1, EAP1, HWP1, and SAP 2-4-5-6 gene expression by quantitative RT-PCR. Results This study demonstrates that KSL-W markedly reduced C. albicans growth at both early and late incubation times. The significant effect of KSL-W on C. albicans growth was observed beginning at 10 μg/ml after 5 h of contact by reducing C. albicans transition and at 25 μg/ml by completely inhibiting C. albicans transition. Cultured C. albicans under biofilm-inducing conditions revealed that both KSL-W and amphotericin B significantly decreased biofilm formation at 2, 4, and 6 days of culture. KSL-W also disrupted mature C. albicans biofilms. The effect of KSL-W on C. albicans growth, transition, and biofilm formation/disruption may thus occur through gene modulation, as the expression of various genes involved in C. albicans growth, transition and biofilm formation were all downregulated when C. albicans was treated with KSL-W. The effect was greater when C. albicans was cultured under hyphae-inducing conditions. Conclusions These data provide new insight into the efficacy of KSL-W against C. albicans and its potential use as an antifungal therapy. PMID:24195531

  13. 24 CFR 241.875 - Maximum claim period.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Maximum claim period. 241.875 Section 241.875 Housing and Urban Development Regulations Relating to Housing and Urban Development... § 241.875 Maximum claim period. Notice of intention to file claim on a form prescribed by the...

  14. 24 CFR 35.320 - Hazard reduction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Hazard reduction. 35.320 Section 35.320 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Project-Based Assistance...

  15. 24 CFR 35.320 - Hazard reduction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Hazard reduction. 35.320 Section 35.320 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Project-Based Assistance...

  16. 24 CFR 35.320 - Hazard reduction.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Hazard reduction. 35.320 Section 35.320 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Project-Based Assistance...

  17. 24 CFR 35.320 - Hazard reduction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Hazard reduction. 35.320 Section 35.320 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Project-Based Assistance...

  18. 24 CFR 35.320 - Hazard reduction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Hazard reduction. 35.320 Section 35.320 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Project-Based Assistance...

  19. 20 CFR 410.320 - Determination of relationship; widow.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Determination of relationship; widow. 410.320 Section 410.320 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Relationship and Dependency § 410.320 Determination of...

  20. 20 CFR 410.320 - Determination of relationship; widow.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Determination of relationship; widow. 410.320 Section 410.320 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Relationship and Dependency § 410.320 Determination of...

  1. 21 CFR 320.63 - Retention of bioequivalence samples.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Retention of bioequivalence samples. 320.63 Section 320.63 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... the Bioavailability or Bioequivalence of Drug Products § 320.63 Retention of bioequivalence samples...

  2. 21 CFR 320.63 - Retention of bioequivalence samples.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Retention of bioequivalence samples. 320.63 Section 320.63 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... the Bioavailability or Bioequivalence of Drug Products § 320.63 Retention of bioequivalence samples...

  3. 40 CFR 241.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OR INGREDIENTS IN COMBUSTION UNITS General § 241.2 Definitions. For the purposes of this subpart... products of incomplete combustion. Contained means the non-hazardous secondary material is stored in a... with section 241.3(b)(2)(i) from the point of removal from the vehicle through arrival at the...

  4. 18 CFR 24.1 - Filing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Filing. 24.1 Section 24.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF... initial and ultimate installed capacity of the project, the rated horsepower and head on the turbines, and...

  5. 18 CFR 24.1 - Filing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Filing. 24.1 Section 24.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF... initial and ultimate installed capacity of the project, the rated horsepower and head on the turbines, and...

  6. 18 CFR 24.1 - Filing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Filing. 24.1 Section 24.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF... initial and ultimate installed capacity of the project, the rated horsepower and head on the turbines, and...

  7. 39 CFR 241.2 - Stations and branches.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... number, letter or name. As a general rule, branches are named. (2) Stations and branches transact... 39 Postal Service 1 2012-07-01 2012-07-01 false Stations and branches. 241.2 Section 241.2 Postal... DISCONTINUANCE § 241.2 Stations and branches. (a) Description. (1) Stations are established within the corporate...

  8. 39 CFR 241.2 - Stations and branches.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... number, letter or name. As a general rule, branches are named. (2) Stations and branches transact... 39 Postal Service 1 2013-07-01 2013-07-01 false Stations and branches. 241.2 Section 241.2 Postal... DISCONTINUANCE § 241.2 Stations and branches. (a) Description. (1) Stations are established within the corporate...

  9. 39 CFR 241.2 - Stations and branches.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... number, letter or name. As a general rule, branches are named. (2) Stations and branches transact... 39 Postal Service 1 2014-07-01 2014-07-01 false Stations and branches. 241.2 Section 241.2 Postal... DISCONTINUANCE § 241.2 Stations and branches. (a) Description. (1) Stations are established within the corporate...

  10. 39 CFR 241.2 - Stations and branches.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... number, letter or name. As a general rule, branches are named. (2) Stations and branches transact... 39 Postal Service 1 2011-07-01 2011-07-01 false Stations and branches. 241.2 Section 241.2 Postal... DISCONTINUANCE § 241.2 Stations and branches. (a) Description. (1) Stations are established within the corporate...

  11. 39 CFR 241.2 - Stations and branches.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... number, letter or name. As a general rule, branches are named. (2) Stations and branches transact... 39 Postal Service 1 2010-07-01 2010-07-01 false Stations and branches. 241.2 Section 241.2 Postal... DISCONTINUANCE § 241.2 Stations and branches. (a) Description. (1) Stations are established within the corporate...

  12. STS-106 Crew Activity Report/Flight Day 1 Highlights

    NASA Technical Reports Server (NTRS)

    2000-01-01

    On this first day of the STS-106 Atlantis mission, the flight crew, Commander Terrence W. Wilcutt, Pilot Scott D. Altman, and Mission Specialists Daniel C. Burbank, Edward T. Lu, Richard A. Mastracchio, Yuri Ivanovich Malenchenko, and Boris V. Morukov are seen performing pre-launch activities. They are shown sitting around the breakfast table with the traditional cake, suiting-up, and riding out to the launch pad. The final inspection team is seen as they conduct their final check of the space shuttle on the launch complex. Also, included are various panoramic views of the shuttle on the pad. The crew is readied in the 'white room' for their mission. After the closing of the hatch and arm retraction, launch activities are shown including countdown, engine ignition, launch, and the separation of the Solid Rocket Boosters.

  13. STS-106 Crew Activities Report/Flight Day 07 Highlights

    NASA Technical Reports Server (NTRS)

    2000-01-01

    On this seventh day of the STS-106 Atlantis mission, the flight crew, Commander Commander Terrence W. Wilcutt, Pilot Scott D. Altman, and Mission Specialists Daniel C. Burbank, Edward T. Lu, Richard A. Mastracchio, Yuri Ivanovich Malenchenko, and Boris V. Morukov are seen participating in several outfitting activities. Burbank and Morukov remove and replace a fourth battery in Zarya. Lu and Malenchenko finish installing the third and final battery and other electrical equipment inside the Zvezda Service Module. While Altman and Wilcutt perform a series of jet firings, Altman is shown as he narrates a tour of the Zvezda Service Module. Scenes also include Lu and Malenchenko unpacking the Russian-made Orlan space suits, Burbank and Wilcutt participating in an interview, and a beautiful night shot of the International Space Station (ISS) and Atlantis complex above the Earth.

  14. MicroRNA-320 involves in the cardioprotective effect of insulin against myocardial ischemia by targeting survivin.

    PubMed

    Yang, Ni; Wu, Liuzhong; Zhao, Ying; Zou, Ning; Liu, Chunfeng

    2018-04-01

    It is generally accepted that insulin exerts an antiapoptotic effect against ischemia/reperfusion through the activation of PI3K/Akt/mTOR pathway. MicroRNAs involve in multiple cardiac pathophysiological processes, including ischemia/reperfusion-induced cardiac injury. However, the regulation of microRNAs in the cardioprotective effect of insulin is rarely discussed. In this study, using a cell model of ischemia through culturing H9C2 cardiac myocytes in serum-free medium with hypoxia, we demonstrated that pretreatment with insulin significantly inhibited cell apoptosis and downregulated microRNA-320 (miR-320) expression. Interestingly, miR-320 mimic impaired the cardioprotective effect of insulin against myocardial ischemia injury by targeting survivin, which is a member of the family of inhibitor of apoptosis proteins. Suppression miR-320 expression by miR-320 inhibitor in H9C2 cells with myocardial ischemia mimics the cardioprotective effect of insulin by maintaining survivin expression. Taken together, miR-320-mediated survivin expression involves in cardioprotective effect of insulin against myocardial ischemia injury. Myocardial ischemia/reperfusion (I/R) injury remains an important clinical problem with extremely deficient clinical therapies. Insulin exerts an antiapoptotic effect against I/R through the activation of PI3K/Akt/mTOR pathway. Here, we provided evidences to show that microRNA-320 involves in the cardioprotective effect of insulin by targeting survivin, which is an inhibitor of apoptosis protein and functions as a key regulator in cell apoptosis and involves in the tumour genesis and progression. Our findings may provide a new potential therapeutic strategy for I/R injury and ischemic heart disease. Copyright © 2018 John Wiley & Sons, Ltd.

  15. Ada Compiler Validation Summary Report: Certificate Number: 900726W1. 11019, Verdix Corporation, VADS Prime EXL/320, UNIX System V/386 3.2, Vada-110- 3232, Version 6.0, Prime EXL/320 Greater Than or Equal to Prime EXL/320

    DTIC Science & Technology

    1991-01-22

    EXL/320, UNIX System V/386 3.2 Customer Agreement Number: 90-05-29- VRX See Section 3.1 for any additional information about the testing environment. As...Distribution/ Washington DC 20301 Availability Codes 05i jAvail and/or Dist SpeaL&L. AVF Control Number: AVF-VSR-376.0191 22 January 1991 90-05-29- VRX Ada

  16. Eclipse project QF-106 and C-141A climbs out under tow on first tethered flight December 20, 1997

    NASA Technical Reports Server (NTRS)

    1997-01-01

    TOW LAUNCH DEMONSTRATION - The Kelly Space & Technology (KST)/USAF/NASA Eclipse project's modified QF-106 climbs out under tow by a USAF C-141A on the project's first tethered flight on December 20, 1997. The successful 18-minute-long flight reached an altitude of 10,000 feet. NASA's Dryden Flight Research Center, Edwards, California, hosted the project, providing engineering and facility support as well as the project pilot. In 1997 and 1998, the Dryden Flight Research Center at Edwards, California, supported and hosted a Kelly Space & Technology, Inc. project called Eclipse, which sought to demonstrate the feasibility of a reusable tow-launch vehicle concept. The project goal was to successfully tow, inflight, a modified QF-106 delta-wing aircraft with an Air Force C-141A transport aircraft. This would demonstrate the possibility of towing and launching an actual launch vehicle from behind a tow plane. Dryden was the responsible test organization and had flight safety responsibility for the Eclipse project. Dryden provided engineering, instrumentation, simulation, modification, maintenance, range support, and research pilots for the test program. The Air Force Flight Test Center (AFFTC), Edwards, California, supplied the C-141A transport aircraft and crew and configured the aircraft as needed for the tests. The AFFTC also provided the concept and detail design and analysis as well as hardware for the tow system and QF-106 modifications. Dryden performed the modifications to convert the QF-106 drone into the piloted EXD-01 (Eclipse eXperimental Demonstrator-01) experimental aircraft. Kelly Space & Technology hoped to use the results gleaned from the tow test in developing a series of low-cost, reusable launch vehicles. These tests demonstrated the validity of towing a delta-wing aircraft having high wing loading, validated the tow simulation model, and demonstrated various operational procedures, such as ground processing of in-flight maneuvers and emergency abort

  17. 24 CFR 235.320 - Limitation of sales price.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Limitation of sales price. 235.320 Section 235.320 Housing and Urban Development Regulations Relating to Housing and Urban Development... Payments-Homes for Lower Income Families § 235.320 Limitation of sales price. To qualify for assistance...

  18. 24 CFR 235.320 - Limitation of sales price.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Limitation of sales price. 235.320 Section 235.320 Housing and Urban Development Regulations Relating to Housing and Urban Development... Payments-Homes for Lower Income Families § 235.320 Limitation of sales price. To qualify for assistance...

  19. 15 CFR 904.320 - Nature of permit sanctions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Nature of permit sanctions. 904.320 Section 904.320 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued... PROCEDURES Permit Sanctions and Denials Permit Sanction for Violations § 904.320 Nature of permit sanctions...

  20. 15 CFR 904.320 - Nature of permit sanctions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 3 2013-01-01 2013-01-01 false Nature of permit sanctions. 904.320 Section 904.320 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued... PROCEDURES Permit Sanctions and Denials Permit Sanction for Violations § 904.320 Nature of permit sanctions...

  1. 15 CFR 904.320 - Nature of permit sanctions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Nature of permit sanctions. 904.320 Section 904.320 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued... PROCEDURES Permit Sanctions and Denials Permit Sanction for Violations § 904.320 Nature of permit sanctions...

  2. 15 CFR 904.320 - Nature of permit sanctions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 3 2014-01-01 2014-01-01 false Nature of permit sanctions. 904.320 Section 904.320 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued... PROCEDURES Permit Sanctions and Denials Permit Sanction for Violations § 904.320 Nature of permit sanctions...

  3. 15 CFR 904.320 - Nature of permit sanctions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 3 2012-01-01 2012-01-01 false Nature of permit sanctions. 904.320 Section 904.320 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued... PROCEDURES Permit Sanctions and Denials Permit Sanction for Violations § 904.320 Nature of permit sanctions...

  4. 24 CFR 320.10 - Financial reporting.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Financial reporting. 320.10 Section...-BACKED SECURITIES Pass-Through Type Securities § 320.10 Financial reporting. Issuers shall submit to the Association audited annual financial statements within 90 days of their fiscal year end. All financial...

  5. 24 CFR 320.11 - Insurance coverage.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Insurance coverage. 320.11 Section...-BACKED SECURITIES Pass-Through Type Securities § 320.11 Insurance coverage. The issuer shall maintain, for the benefit of the Association, insurance, errors and omissions, fidelity bond and other coverage...

  6. 24 CFR 583.320 - Site control.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Site control. 583.320 Section 583... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Program Requirements § 583.320 Site control. (a) Site control. (1) Where grant funds will be used for acquisition, rehabilitation, or new construction...

  7. 24 CFR 583.320 - Site control.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 3 2013-04-01 2013-04-01 false Site control. 583.320 Section 583... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Program Requirements § 583.320 Site control. (a) Site control. (1) Where grant funds will be used for acquisition, rehabilitation, or new construction...

  8. 24 CFR 583.320 - Site control.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 3 2014-04-01 2013-04-01 true Site control. 583.320 Section 583... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Program Requirements § 583.320 Site control. (a) Site control. (1) Where grant funds will be used for acquisition, rehabilitation, or new construction...

  9. 24 CFR 583.320 - Site control.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Site control. 583.320 Section 583... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Program Requirements § 583.320 Site control. (a) Site control. (1) Where grant funds will be used for acquisition, rehabilitation, or new construction...

  10. 24 CFR 583.320 - Site control.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 3 2012-04-01 2012-04-01 false Site control. 583.320 Section 583... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Program Requirements § 583.320 Site control. (a) Site control. (1) Where grant funds will be used for acquisition, rehabilitation, or new construction...

  11. 24 CFR 320.10 - Financial reporting.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Financial reporting. 320.10 Section...-BACKED SECURITIES Pass-Through Type Securities § 320.10 Financial reporting. Issuers shall submit to the Association audited annual financial statements within 90 days of their fiscal year end. All financial...

  12. 32 CFR 241.10 - Small business consideration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Small business consideration. 241.10 Section 241...) § 241.10 Small business consideration. The ASD(NII)/DoD CIO on behalf of the Secretary of Defense shall: (a) Ensure that, of the assignments made each year, at least 20 percent are small business concerns...

  13. Preparation of W/CuCrZr mono-block test mock-up using vacuum brazing technique

    NASA Astrophysics Data System (ADS)

    Premjit Singh, K.; Khirwadkar, S.; Bhope, Kedar; Patel, Nikunj; Mokaria, Prakash

    2017-04-01

    Development of the joining for W/CuCrZr mono-block PFC test mock-up is an interesting area in Fusion R&D. W/Cu bimetallic material has been prepared using OFHC Copper casting approach on the radial surface of W mono-block tile surface. The W/Cu bimetallic material has been joined with CuCrZr tube (heat sink) material with the vacuum brazing route. Vacuum brazing of W/Cu-CuCrZr has been performed @ 970°C for 10 min using NiCuMn-37 filler material under deep vacuum environment (10-6 mbar). Graphite fixture was used for OFHC Copper casting and vacuum brazing experiments. The joint integrity of W/Cu-CuCrZr mono-block mock-up of W/Cu and Cu-CuCrZr interface has been checked using ultrasonic immersion technique. The result of the experimental work is presented in the paper.

  14. 27 CFR 25.241 - Production.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Production. 25.241 Section... THE TREASURY LIQUORS BEER Cereal Beverage § 25.241 Production. Brewers may produce cereal beverage and remove it without payment of tax from the brewery. The method of production shall insure that the alcohol...

  15. 27 CFR 24.320 - Chemical record.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Chemical record. 24.320... OF THE TREASURY LIQUORS WINE Records and Reports § 24.320 Chemical record. A proprietor who uses chemicals, preservatives, or other such materials shall maintain a record of the purchase, receipt and...

  16. 27 CFR 24.320 - Chemical record.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Chemical record. 24.320... OF THE TREASURY LIQUORS WINE Records and Reports § 24.320 Chemical record. A proprietor who uses chemicals, preservatives, or other such materials shall maintain a record of the purchase, receipt and...

  17. 27 CFR 24.320 - Chemical record.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Chemical record. 24.320... OF THE TREASURY LIQUORS WINE Records and Reports § 24.320 Chemical record. A proprietor who uses chemicals, preservatives, or other such materials shall maintain a record of the purchase, receipt and...

  18. 27 CFR 24.320 - Chemical record.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Chemical record. 24.320... OF THE TREASURY ALCOHOL WINE Records and Reports § 24.320 Chemical record. A proprietor who uses chemicals, preservatives, or other such materials shall maintain a record of the purchase, receipt and...

  19. 27 CFR 24.320 - Chemical record.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Chemical record. 24.320... OF THE TREASURY ALCOHOL WINE Records and Reports § 24.320 Chemical record. A proprietor who uses chemicals, preservatives, or other such materials shall maintain a record of the purchase, receipt and...

  20. 21 CFR 172.320 - Amino acids.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Amino acids. 172.320 Section 172.320 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Special Dietary and Nutritional Additives § 172...

  1. Recrystallization behavior and thermal shock resistance of the W-1.0 wt% TaC alloy

    NASA Astrophysics Data System (ADS)

    Xie, Z. M.; Miao, S.; Zhang, T.; Liu, R.; Wang, X. P.; Fang, Q. F.; Hao, T.; Zhuang, Z.; Liu, C. S.; Lian, Y. Y.; Liu, X.; Cai, L. H.

    2018-04-01

    The high-temperature stability and good mechanical strength of tungsten (W) alloys are highly desirable for a wide range of fusion applications, which can be achieved by dispersion strengthening. In this paper, TaC dispersion effects on the thermal stabilities, tensile properties and thermal shock resistances have been investigated. A hot-rolled W-1.0 wt% TaC plate has been fabricated which contains the high tensile strength and elongation. Nanosized particles in the W matrix improve the recrystallization temperature to about 1400 °C and the ultimate tensile strength to 571 MPa at 500 °C through hindering grain boundary migration, pinning dislocations and refining grains. The effects of edge-localized mode like transient heat events on the rolled and recrystallized W-1.0 wt% TaC alloys were investigated systematically. The cracking threshold (100 shots) at room temperature is in the range of 0.33-0.44 GW/m2 for the rolled W-1.0 wt% TaC. Recrystallization degrades mechanical strength and makes the material more prone to thermal shock damages. Coarse Ta2O5 and Ta-Cx-Oy particles are easy to fracture and introduce a preferential crack initiation in W matrix during cyclic heat loads.

  2. 46 CFR 181.320 - Fire hoses and nozzles.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Fire hoses and nozzles. 181.320 Section 181.320 Shipping...) FIRE PROTECTION EQUIPMENT Fire Main System § 181.320 Fire hoses and nozzles. (a) A fire hose with a... cargo decks, where no protection is provided, hoses may be temporarily removed during heavy weather or...

  3. 46 CFR 181.320 - Fire hoses and nozzles.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Fire hoses and nozzles. 181.320 Section 181.320 Shipping...) FIRE PROTECTION EQUIPMENT Fire Main System § 181.320 Fire hoses and nozzles. (a) A fire hose with a... cargo decks, where no protection is provided, hoses may be temporarily removed during heavy weather or...

  4. 46 CFR 181.320 - Fire hoses and nozzles.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Fire hoses and nozzles. 181.320 Section 181.320 Shipping...) FIRE PROTECTION EQUIPMENT Fire Main System § 181.320 Fire hoses and nozzles. (a) A fire hose with a... cargo decks, where no protection is provided, hoses may be temporarily removed during heavy weather or...

  5. 46 CFR 181.320 - Fire hoses and nozzles.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Fire hoses and nozzles. 181.320 Section 181.320 Shipping...) FIRE PROTECTION EQUIPMENT Fire Main System § 181.320 Fire hoses and nozzles. (a) A fire hose with a... cargo decks, where no protection is provided, hoses may be temporarily removed during heavy weather or...

  6. 29 CFR 780.320 - Nonlocal minors.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... That Is Exempted From the Minimum Wage and Overtime Pay Requirements Under Section 13(a)(6) Statutory... 29 Labor 3 2010-07-01 2010-07-01 false Nonlocal minors. 780.320 Section 780.320 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR...

  7. 46 CFR 181.320 - Fire hoses and nozzles.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Fire hoses and nozzles. 181.320 Section 181.320 Shipping...) FIRE PROTECTION EQUIPMENT Fire Main System § 181.320 Fire hoses and nozzles. (a) A fire hose with a nozzle must be attached to each fire hydrant at all times. For fire hydrants located on open decks or...

  8. PCC properties to support w/c determination for durability.

    DOT National Transportation Integrated Search

    2012-10-01

    The fresh concrete watercement ratio (w/c) determination tool is urgently needed for use in the QC/QA process at the job site. Various : techniques have been used in the past to determine this parameter. However, many of these techniques can be co...

  9. Concordant 241Pu-241Am Dating of Environmental Samples: Results from Forest Fire Ash

    NASA Astrophysics Data System (ADS)

    Goldstein, S. J.; Oldham, W. J.; Murrell, M. T.; Katzman, D.

    2010-12-01

    We have measured the Pu, 237Np, 241Am, and 151Sm isotopic systematics for a set of forest fire ash samples from various locations in the western U.S. including Montana, Wyoming, Idaho, and New Mexico. The goal of this study is to develop a concordant 241Pu (t1/2 = 14.4 y)-241Am dating method for environmental collections. Environmental samples often contain mixtures of components including global fallout. There are a number of approaches for subtracting the global fallout component for such samples. One approach is to use 242Pu/239Pu as a normalizing isotope ratio in a three-isotope plot, where this ratio for the non-global fallout component can be estimated or assumed to be small. This study investigates a new, complementary method of normalization using the long-lived fission product, 151Sm (t1/2 = 90 y). We find that forest fire ash concentrates actinides and fission products with ~1E10 atoms 239Pu/g and ~1E8 atoms 151Sm/g, allowing us to measure these nuclides by mass spectrometric (MIC-TIMS) and radiometric (liquid scintillation counting) methods. The forest fire ash samples are characterized by a western U.S. regional isotopic signature representing varying mixtures of global fallout with a local component from atmospheric testing of nuclear weapons at the Nevada Test Site (NTS). Our results also show that 151Sm is well correlated with the Pu nuclides in the forest fire ash, suggesting that these nuclides have similar geochemical behavior in the environment. Results of this correlation indicate that the 151Sm/239Pu atom ratio for global fallout is ~0.164, in agreement with an independent estimate of 0.165 based on 137Cs fission yields for atmospheric weapons tests at the NTS. 241Pu-241Am dating of the non-global fallout component in the forest fire ash samples yield ages in the late 1950’s-early 1960’s, consistent with a peak in NTS weapons testing at that time. The age results for this component are in agreement using both 242Pu and 151Sm normalizations

  10. 152 W average power Tm-doped fiber CPA system.

    PubMed

    Stutzki, Fabian; Gaida, Christian; Gebhardt, Martin; Jansen, Florian; Wienke, Andreas; Zeitner, Uwe; Fuchs, Frank; Jauregui, Cesar; Wandt, Dieter; Kracht, Dietmar; Limpert, Jens; Tünnermann, Andreas

    2014-08-15

    A high-power thulium (Tm)-doped fiber chirped-pulse amplification system emitting a record compressed average output power of 152 W and 4 MW peak power is demonstrated. This result is enabled by utilizing Tm-doped photonic crystal fibers with mode-field diameters of 35 μm, which mitigate detrimental nonlinearities, exhibit slope efficiencies of more than 50%, and allow for reaching a pump-power-limited average output power of 241 W. The high-compression efficiency has been achieved by using multilayer dielectric gratings with diffraction efficiencies higher than 98%.

  11. Lack of tyrosine 320 impairs spontaneous endocytosis and enhances release of HLA-B27 molecules.

    PubMed

    Santos, Susana G; Antoniou, Antony N; Sampaio, Paula; Powis, Simon J; Arosa, Fernando A

    2006-03-01

    Several lines of evidence suggest that endocytosis of MHC class I molecules requires conserved motifs within the cytoplasmic domain. In this study, we show, in the C58 rat thymoma cell line transfected with HLA-B27 molecules, that replacement of the highly conserved tyrosine (Tyr320) in the cytoplasmic domain of HLA-B27 does not hamper cell surface expression of beta2-microglobulin H chain heterodimers or formation of misfolded molecules. However, Tyr320 replacement markedly impairs spontaneous endocytosis of HLA-B27. Although wild-type molecules are mostly internalized via endosomal compartments, Tyr320-mutated molecules remain at the plasma membrane in which partial colocalization with endogenous transferrin receptors can be observed, also impairing their endocytosis. Finally, we show that Tyr320 substitution enhances release of cleaved forms of HLA-B27 from the cell surface. These studies show for the first time that Tyr320 is most likely part of a cytoplasmic sorting motif involved in spontaneous endocytosis and shedding of MHC class I molecules.

  12. Extending Matchings in Graphs: A Survey

    DTIC Science & Technology

    1990-01-01

    private communication from, 1989. [11] D.A. Holton, D. Lou and M.D. Plummer, On the 2-extendability of planar graphs, Discrete Math ., (to appear). [12...222. [231 L. Lovasz and M.D. Plummer, Matching Theory, Ann. Discrete Math . 29, North- Holland, Amsterdam, 1986. [241 W.S. Massey, Algebraic Topology...Plummer, On n-extendable graphs, Discrete Math . 31, 1980, 201-210. [341 , Toughness and matching extension in graphs, Discrete Math . 72, 1988, 311-320

  13. 40 CFR 436.241 - Specialized definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 31 2013-07-01 2013-07-01 false Specialized definitions. 436.241 Section 436.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Diatomite Subcategory...

  14. 40 CFR 436.241 - Specialized definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 31 2012-07-01 2012-07-01 false Specialized definitions. 436.241 Section 436.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Diatomite Subcategory...

  15. 40 CFR 436.241 - Specialized definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 30 2014-07-01 2014-07-01 false Specialized definitions. 436.241 Section 436.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Diatomite Subcategory...

  16. 31 CFR 515.320 - Domestic bank.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Domestic bank. 515.320 Section 515.320... Domestic bank. The term domestic bank shall mean any branch or office within the United States of any of the following which is not a national of a designated foreign country; any bank or trust company...

  17. 31 CFR 515.320 - Domestic bank.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Domestic bank. 515.320 Section 515... § 515.320 Domestic bank. The term domestic bank shall mean any branch or office within the United States of any of the following which is not a national of a designated foreign country; any bank or trust...

  18. 31 CFR 500.320 - Domestic bank.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Domestic bank. 500.320 Section 500... § 500.320 Domestic bank. The term domestic bank shall mean any branch or office within the United States of any of the following which is not a national of any designated foreign country: Any bank or trust...

  19. 31 CFR 535.320 - Domestic bank.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Domestic bank. 535.320 Section 535... § 535.320 Domestic bank. (a) The term domestic bank shall mean any branch or office within the United States of any of the following which is not Iran or an Iranian entity: any bank or trust company...

  20. Whole Device Modeling of Compact Tori: Stability and Transport Modeling of C-2W

    NASA Astrophysics Data System (ADS)

    Dettrick, Sean; Fulton, Daniel; Lau, Calvin; Lin, Zhihong; Ceccherini, Francesco; Galeotti, Laura; Gupta, Sangeeta; Onofri, Marco; Tajima, Toshiki; TAE Team

    2017-10-01

    Recent experimental evidence from the C-2U FRC experiment shows that the confinement of energy improves with inverse collisionality, similar to other high beta toroidal devices, NSTX and MAST. This motivated the construction of a new FRC experiment, C-2W, to study the energy confinement scaling at higher electron temperature. Tri Alpha Energy is working towards catalysing a community-wide collaboration to develop a Whole Device Model (WDM) of Compact Tori. One application of the WDM is the study of stability and transport properties of C-2W using two particle-in-cell codes, ANC and FPIC. These codes can be used to find new stable operating points, and to make predictions of the turbulent transport at those points. They will be used in collaboration with the C-2W experimental program to validate the codes against C-2W, mitigate experimental risk inherent in the exploration of new parameter regimes, accelerate the optimization of experimental operating scenarios, and to find operating points for future FRC reactor designs.

  1. The influence of aggregates type on W/C ratio on the strength and other properties of concrete

    NASA Astrophysics Data System (ADS)

    Malaiskiene, J.; Skripkiunas, G.; Vaiciene, M.; Karpova, E.

    2017-10-01

    The influence of different types of aggregates and W/C ratio on concrete properties is analysed. In order to achieve this aim, lightweight (with expanded clay aggregate) and normal concrete (with gravel aggregate) mixtures are prepared with different W/C ratios. Different W/C ratios are selected by reducing the amount of cement when the amount of water is constant. The following properties of concrete have been determined: density, compressive strength and water absorption. Additionally, the statistical data analysis is performed and influence of aggregate type and W/C ratio on concrete properties is determined. The empirical equations indicating dependence between concrete strength and W/C and strength of aggregate are obtained for normal concrete and light-weight concrete.

  2. How Does Mg2+ Modulate the RNA Folding Mechanism: A Case Study of the G:C W:W Trans Basepair.

    PubMed

    Halder, Antarip; Roy, Rohit; Bhattacharyya, Dhananjay; Mitra, Abhijit

    2017-07-25

    Reverse Watson-Crick G:C basepairs (G:C W:W Trans) occur frequently in different functional RNAs. This is one of the few basepairs whose gas-phase-optimized isolated geometry is inconsistent with the corresponding experimental geometry. Several earlier studies indicate that through post-transcriptional modification, direct protonation, or coordination with Mg 2+ , accumulation of positive charge near N7 of guanine can stabilize the experimental geometry. Interestingly, recent studies reveal significant variation in the position of putatively bound Mg 2+ . This, in conjunction with recently raised doubts regarding some of the Mg 2+ assignments near the imino nitrogen of guanine, is suggestive of the existence of multiple Mg 2+ binding modes for this basepair. Our detailed investigation of Mg 2+ -bound G:C W:W Trans pairs occurring in high-resolution RNA crystal structures shows that they are found in 14 different contexts, eight of which display Mg 2+ binding at the Hoogsteen edge of guanine. Further examination of occurrences in these eight contexts led to the characterization of three different Mg 2+ binding modes: 1) direct binding via N7 coordination, 2) direct binding via O6 coordination, and 3) binding via hydrogen-bonding interaction with the first-shell water molecules. In the crystal structures, the latter two modes are associated with a buckled and propeller-twisted geometry of the basepair. Interestingly, respective optimized geometries of these different Mg 2+ binding modes (optimized using six different DFT functionals) are consistent with their corresponding experimental geometries. Subsequent interaction energy calculations at the MP2 level, and decomposition of its components, suggest that for G:C W:W Trans , Mg 2+ binding can fine tune the basepair geometries without compromising with their stability. Our results, therefore, underline the importance of the mode of binding of Mg 2+ ions in shaping RNA structure, folding and function. Copyright

  3. 33 CFR 136.241 - Compensation allowable.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Compensation allowable. 136.241 Section 136.241 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

  4. 33 CFR 136.241 - Compensation allowable.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Compensation allowable. 136.241 Section 136.241 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

  5. 33 CFR 136.241 - Compensation allowable.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Compensation allowable. 136.241 Section 136.241 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

  6. 33 CFR 136.241 - Compensation allowable.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Compensation allowable. 136.241 Section 136.241 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

  7. 33 CFR 136.241 - Compensation allowable.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Compensation allowable. 136.241 Section 136.241 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

  8. MicroRNA-320a inhibits breast cancer metastasis by targeting metadherin

    PubMed Central

    Zhang, Lei; Yang, Hai-Ping; Wang, Lei; Ding, Di; Chen, Qi; Yang, Wen-Lin; Ren, Ke-Han; Zhou, Dan-Mei; Zou, Qiang; Jin, Yi-Ting; Liu, Xiu-Ping

    2016-01-01

    Dysregulated microRNAs play important pathological roles in carcinogenesis that are yet to be fully elucidated. This study was performed to investigate the biological functions of microRNA-320a (miR-320a) in breast cancer and the underlying mechanisms. Function analyses for cell proliferation, cell cycle, and cell invasion/migration, were conducted after miR-320a silencing and overexpression. The specific target genes of miR-320a were predicted by TargetScan algorithm and then determined by dual luciferase reporter assay and rescue experiment. The relationship between miR-320a and its target genes was explored in human breast cancer tissues. We found that miR-320a overexpression could inhibit breast cancer invasion and migration abilities in vitro, while miR-320a silencing could enhance that. In addition, miR-320a could suppress activity of 3′-untranslated region luciferase of metadherin (MTDH), a potent oncogene. The rescue experiment revealed that MTDH was a functional target of miR-320a. Moreover, we found that MTDH was negatively correlated with miR-320a expression, and it was related to clinical outcomes of breast cancer. Further xenograft experiment also showed that miR-320a could inhibit breast cancer metastasis in vivo. Our findings clearly demonstrate that miR-320a suppresses breast cancer metastasis by directly inhibiting MTDH expression. The present study provides a new insight into anti-oncogenic roles of miR-320a and suggests that miR-320a/MTDH pathway is a putative therapeutic target in breast cancer. PMID:27229534

  9. 28 CFR 32.0 - Scope of part.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Scope of part. 32.0 Section 32.0 Judicial Administration DEPARTMENT OF JUSTICE PUBLIC SAFETY OFFICERS' DEATH, DISABILITY, AND EDUCATIONAL ASSISTANCE...) Educational assistance benefits. [73 FR 76528, Dec. 17, 2008] ...

  10. 28 CFR 32.0 - Scope of part.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Scope of part. 32.0 Section 32.0 Judicial Administration DEPARTMENT OF JUSTICE PUBLIC SAFETY OFFICERS' DEATH, DISABILITY, AND EDUCATIONAL ASSISTANCE...) Educational assistance benefits. [73 FR 76528, Dec. 17, 2008] ...

  11. STS-106 Crew Activity Report / Flight Day Highlights Day 2

    NASA Technical Reports Server (NTRS)

    2000-01-01

    STS-106 was launched on Sept 8, 2000 at 8:45 a.m. The crew was commanded by Terrence W. Wilcutt, the pilot was Scott D. Altman. The mission specialists were Daniel C. Burbank, Edward T. Lu, Richard A. Mastracchio, Yuri Ivanovich Malenchenko, and Boris V. Morukov. During the 11-day mission, the crew spent a week inside the International Space Station (ISS) unloading supplies from both a double SPACEHAB cargo module in the rear of the Atlantis cargo bay and from a Russian Progress M-1 resupply craft docked to the aft end of the Zvezda Service Module. The videotape shows the activities of the second day of the flight and the preparations for docking with the ISS. Shown on the video are shots of the flight deck on the shuttle, the shuttle payload arm, and shots of the crew eating lunch.

  12. W + Jet Production at Cdf

    NASA Astrophysics Data System (ADS)

    Messina, Andrea

    2007-01-01

    The cross section for the inclusive production of W bosons in association with jets in pbar {p} collisions at √ {s} = 1.96\\ TeV using the Collider Detector at Fermilab (CDF II) is presented. The measurement is based on an integrated luminosity of 320 pb-1, and includes events with up to 4 or more jets. In each jet multiplicity sample the differential and cumulative cross sections with respect to the transverse energy of the ith-jet are measured. For W + ≥ 2 jets the differential cross section with respect to the 2-leading jets invariant mass mj1j2 and angular separation ΔRj1j2 is also reported. The data are compared to predictions from Monte Carlo simulations.

  13. Structure Modulates Similarity-Based Interference in Sluicing: An Eye Tracking study

    PubMed Central

    Harris, Jesse A.

    2015-01-01

    In cue-based content-addressable approaches to memory, a target and its competitors are retrieved in parallel from memory via a fast, associative cue-matching procedure under a severely limited focus of attention. Such a parallel matching procedure could in principle ignore the serial order or hierarchical structure characteristic of linguistic relations. I present an eye tracking while reading experiment that investigates whether the sentential position of a potential antecedent modulates the strength of similarity-based interference, a well-studied effect in which increased similarity in features between a target and its competitors results in slower and less accurate retrieval overall. The manipulation trades on an independently established Locality bias in sluiced structures to associate a wh-remnant (which ones) in clausal ellipsis with the most local correlate (some wines), as in The tourists enjoyed some wines, but I don't know which ones. The findings generally support cue-based parsing models of sentence processing that are subject to similarity-based interference in retrieval, and provide additional support to the growing body of evidence that retrieval is sensitive to both the structural position of a target antecedent and its competitors, and the specificity or diagnosticity of retrieval cues. PMID:26733893

  14. Detailed modelling of the circumstellar molecular line emission of the S-type AGB star W Aquilae

    NASA Astrophysics Data System (ADS)

    Danilovich, T.; Bergman, P.; Justtanont, K.; Lombaert, R.; Maercker, M.; Olofsson, H.; Ramstedt, S.; Royer, P.

    2014-09-01

    Context. S-type AGB stars have a C/O ratio which suggests that they are transition objects between oxygen-rich M-type stars and carbon-rich C-type stars. As such, their circumstellar compositions of gas and dust are thought to be sensitive to their precise C/O ratio, and it is therefore of particular interest to examine their circumstellar properties. Aims: We present new Herschel HIFI and PACS sub-millimetre and far-infrared line observations of several molecular species towards the S-type AGB star W Aql. We use these observations, which probe a wide range of gas temperatures, to constrain the circumstellar properties of W Aql, including mass-loss rate and molecular abundances. Methods: We used radiative transfer codes to model the circumstellar dust and molecular line emission to determine circumstellar properties and molecular abundances. We assumed a spherically symmetric envelope formed by a constant mass-loss rate driven by an accelerating wind. Our model includes fully integrated H2O line cooling as part of the solution of the energy balance. Results: We detect circumstellar molecular lines from CO, H2O, SiO, HCN, and, for the first time in an S-type AGB star, NH3. The radiative transfer calculations result in an estimated mass-loss rate for W Aql of 4.0 × 10-6 M⊙ yr-1 based on the 12CO lines. The estimated 12CO/13CO ratio is 29, which is in line with ratios previously derived for S-type AGB stars. We find an H2O abundance of 1.5 × 10-5, which is intermediate to the abundances expected for M and C stars, and an ortho/para ratio for H2O that is consistent with formation at warm temperatures. We find an HCN abundance of 3 × 10-6, and, although no CN lines are detected using HIFI, we are able to put some constraints on the abundance, 6 × 10-6, and distribution of CN in W Aql's circumstellar envelopeusing ground-based data. We find an SiO abundance of 3 × 10-6, and an NH3 abundance of 1.7 × 10-5, confined to a small envelope. If we include uncertainties

  15. 24 CFR 241.1050 - Method of loan payment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Method of loan payment. 241.1050 Section 241.1050 Housing and Urban Development Regulations Relating to Housing and Urban Development...-Eligibility Requirements § 241.1050 Method of loan payment. The loan shall provide for monthly payments on the...

  16. 24 CFR 241.1050 - Method of loan payment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Method of loan payment. 241.1050 Section 241.1050 Housing and Urban Development Regulations Relating to Housing and Urban Development...-Eligibility Requirements § 241.1050 Method of loan payment. The loan shall provide for monthly payments on the...

  17. Concordant plutonium-241-americium-241 dating of environmental samples: results from forest fire ash

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goldstein, Steven J; Oldham, Warren J; Murrell, Michael T

    2010-12-07

    We have measured the Pu, {sup 237}Np, {sup 241}Am, and {sup 151}Sm isotopic systematics for a set of forest fire ash samples from various locations in the western U.S. including Montana, Wyoming, Idaho, and New Mexico. The goal of this study is to develop a concordant {sup 241}Pu (t{sub 1/2} = 14.4 y)-{sup 241}Am dating method for environmental collections. Environmental samples often contain mixtures of components including global fallout. There are a number of approaches for subtracting the global fallout component for such samples. One approach is to use {sup 242}/{sup 239}Pu as a normalizing isotope ratio in a three-isotopemore » plot, where this ratio for the nonglobal fallout component can be estimated or assumed to be small. This study investigates a new, complementary method of normalization using the long-lived fission product, {sup 151}Sm (t{sub 1/2} = 90 y). We find that forest fire ash concentrates actinides and fission products with {approx}1E10 atoms {sup 239}Pu/g and {approx}1E8 atoms {sup 151}Sm/g, allowing us to measure these nuclides by mass spectrometric (MIC-TIMS) and radiometric (liquid scintillation counting) methods. The forest fire ash samples are characterized by a western U.S. regional isotopic signature representing varying mixtures of global fallout with a local component from atmospheric testing of nuclear weapons at the Nevada Test Site (NTS). Our results also show that {sup 151}Sm is well correlated with the Pu nuclides in the forest fire ash, suggesting that these nuclides have similar geochemical behavior in the environment. Results of this correlation indicate that the {sup 151}Sm/{sup 239}Pu atom ratio for global fallout is {approx}0.164, in agreement with an independent estimate of 0.165 based on {sup 137}Cs fission yields for atmospheric weapons tests at the NTS. {sup 241}Pu-{sup 241}Am dating of the non-global fallout component in the forest fire ash samples yield ages in the late 1950's-early 1960's, consistent with a peak

  18. 24 CFR 241.1245 - Insurance endorsement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Insurance endorsement. 241.1245... Rights and Obligations § 241.1245 Insurance endorsement. (a) Endorsement. The Commissioner shall indicate his insurance of the equity loan or acquisition loan by endorsing the original credit instrument and...

  19. 12 CFR 563b.320 - Who has priority to purchase my conversion shares?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... TREASURY CONVERSIONS FROM MUTUAL TO STOCK FORM Standard Conversions Offers and Sales of Stock § 563b.320... order: (a) Eligible account holders. (b) Tax-qualified employee stock ownership plans. (c) Supplemental...

  20. 21 CFR 333.320 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Permitted combinations of active ingredients. 333.320 Section 333.320 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Topical Acne Drug Products § 333.320 Permitted combinations of active ingredients. (a) Resorcinol...

  1. 21 CFR 333.320 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Permitted combinations of active ingredients. 333.320 Section 333.320 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Topical Acne Drug Products § 333.320 Permitted combinations of active ingredients. (a) Resorcinol...

  2. 21 CFR 333.320 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Permitted combinations of active ingredients. 333.320 Section 333.320 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Topical Acne Drug Products § 333.320 Permitted combinations of active ingredients. (a) Resorcinol...

  3. 21 CFR 333.320 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Permitted combinations of active ingredients. 333.320 Section 333.320 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Topical Acne Drug Products § 333.320 Permitted combinations of active ingredients. (a) Resorcinol...

  4. 46 CFR 44.320 - Submission of plans and calculations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Submission of plans and calculations. 44.320 Section 44.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES SPECIAL SERVICE LIMITED DOMESTIC VOYAGES Rules for Assigning Working Freeboards to Hopper Dredges § 44.320 Submission of...

  5. 46 CFR 44.320 - Submission of plans and calculations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Submission of plans and calculations. 44.320 Section 44.320 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES SPECIAL SERVICE LIMITED DOMESTIC VOYAGES Rules for Assigning Working Freeboards to Hopper Dredges § 44.320 Submission of...

  6. 241Am (n,gamma) isomer ratio measurement

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bond, Evelyn M; Vieira, David J; Moody, Walter A

    The objective of this project is to improve the accuracy of the {sup 242}Cm/{sup 241}Am radiochemistry ratio. We have performed an activation experiment to measure the {sup 241}Am(n,{gamma}) cross section leading to either the ground state of {sup 242g}Am (t{sub 1/2} = 16 hr) which decays to {sup 242}Cm (t{sub 1/2} = 163 d) or the long-lived isomer {sup 242m}Am (t{sub 1/2} = 141 yr). This experiment will develop a new set of americium cross section evaluations that can be used with a measured {sup 242}Cm/{sup 241}Am radiochemical measurement for nuclear forensic purposes. This measurement is necessary to interpret themore » {sup 242}Cm/{sup 241}Am ratio because a good measurement of this neutron capture isomer ratio for {sup 241}Am does not exist. The targets were prepared in 2007 from {sup 241}Am purified from LANL stocks. Gold was added to the purified {sup 241}Am as an internal neutron fluence monitor. These targets were placed into a holder, packaged, and shipped to Forschungszentrum Karlsruhe, where they were irradiated at their Van de Graff facility in February 2008. One target was irradiated with {approx}25 keV quasimonoenergetic neutrons produced by the {sup 7}Li(p,n) reaction for 3 days and a second target was also irradiated for 3 days with {approx}500 keV neutrons. Because it will be necessary to separate the {sup 242}Cm from the {sup 241}Am in order to measure the amount of {sup 242}Cm by alpha spectrometry, research into methods for americium/curium separations were conducted concurrently. We found that anion exchange chromatography in methanol/nitric acid solutions produced good separations that could be completed in one day resulting in a sample with no residue. The samples were returned from Germany in July 2009 and were counted by gamma spectrometry. Chemical separations have commenced on the blank sample. Each sample will be spiked with {sup 244}Cm, dissolved and digested in nitric acid solutions. One third of each sample will be processed at a

  7. 34 CFR 303.320 - Public awareness program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Public awareness program. 303.320 Section 303.320 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EARLY INTERVENTION PROGRAM FOR INFANTS AND...

  8. Stagnation, circulation, and erosion of granular materials through belt conveyor sluice gate

    NASA Astrophysics Data System (ADS)

    Pohlman, Nicholas; Moralda, Michael; Dunne, Ryan

    2013-11-01

    Control of flow rates in conversion reactors for discrete materials like biomass can be achieved in belt conveyors through a combination of belt speed, hopper size, and aperture opening. As material is extracted from the bottom of the storage hopper, other material cannot achieve plug flow and therefore is restricted from exiting through a sluice-gate type opening. The excess material moves vertically from the opening causing a pile up and recirculation back along the free surface of the hopper. Experimental results obtained through high speed imaging show the position of the stagnation point as well as the rate of circulation is dependent on the mass flow rate achieved and instantaneous fill level. The movement of material into the plug flow along the belt allows verification of deposition models on erodible beds rather than rigid surfaces with artificial roughness of glued particles. Similarly, the pile-up at the exit influences the efficiency of the transport affecting the narrow energy return on investment of biomass resources. The laboratory-scale behavior can therefore be translated into industrial performance metrics for increased operational efficiency. This work is supported by the NSF REU Site Operation E-Tank under award number 1156789.

  9. 21 CFR 172.320 - Amino acids.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... of total protein (expressed as free amino acid) L-Alanine 6.1 L-Arginine 6.6 L-Aspartic acid... DL-Methionine 3.1 L-Phenylalanine 5.8 L-Proline 4.2 L-Serine 8.4 L-Threonine 5.0 L-Tryptophan 1.6 L... 21 Food and Drugs 3 2012-04-01 2012-04-01 false Amino acids. 172.320 Section 172.320 Food and...

  10. 21 CFR 172.320 - Amino acids.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of total protein (expressed as free amino acid) L-Alanine 6.1 L-Arginine 6.6 L-Aspartic acid... DL-Methionine 3.1 L-Phenylalanine 5.8 L-Proline 4.2 L-Serine 8.4 L-Threonine 5.0 L-Tryptophan 1.6 L... 21 Food and Drugs 3 2011-04-01 2011-04-01 false Amino acids. 172.320 Section 172.320 Food and...

  11. 21 CFR 172.320 - Amino acids.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... of total protein (expressed as free amino acid) L-Alanine 6.1 L-Arginine 6.6 L-Aspartic acid... DL-Methionine 3.1 L-Phenylalanine 5.8 L-Proline 4.2 L-Serine 8.4 L-Threonine 5.0 L-Tryptophan 1.6 L... 21 Food and Drugs 3 2013-04-01 2013-04-01 false Amino acids. 172.320 Section 172.320 Food and...

  12. 21 CFR 172.320 - Amino acids.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of total protein (expressed as free amino acid) L-Alanine 6.1 L-Arginine 6.6 L-Aspartic acid... DL-Methionine 3.1 L-Phenylalanine 5.8 L-Proline 4.2 L-Serine 8.4 L-Threonine 5.0 L-Tryptophan 1.6 L... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Amino acids. 172.320 Section 172.320 Food and Drugs...

  13. 24 CFR 241.635 - Regulatory agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Regulatory agreement. 241.635 Section 241.635 Housing and Urban Development Regulations Relating to Housing and Urban Development... Regulatory agreement. Any borrower obligated on the note for any loan insured under this subpart shall be...

  14. 24 CFR 241.635 - Regulatory agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Regulatory agreement. 241.635 Section 241.635 Housing and Urban Development Regulations Relating to Housing and Urban Development... Regulatory agreement. Any borrower obligated on the note for any loan insured under this subpart shall be...

  15. 24 CFR 241.635 - Regulatory agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Regulatory agreement. 241.635 Section 241.635 Housing and Urban Development Regulations Relating to Housing and Urban Development... Regulatory agreement. Any borrower obligated on the note for any loan insured under this subpart shall be...

  16. 24 CFR 241.635 - Regulatory agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Regulatory agreement. 241.635 Section 241.635 Housing and Urban Development Regulations Relating to Housing and Urban Development... Regulatory agreement. Any borrower obligated on the note for any loan insured under this subpart shall be...

  17. Shark IgW C region diversification through RNA processing and isotype switching.

    PubMed

    Zhang, Cecilia; Du Pasquier, Louis; Hsu, Ellen

    2013-09-15

    Sharks and skates represent the earliest vertebrates with an adaptive immune system based on lymphocyte Ag receptors generated by V(D)J recombination. Shark B cells express two classical Igs, IgM and IgW, encoded by an early, alternative gene organization consisting of numerous autonomous miniloci, where the individual gene cluster carries a few rearranging gene segments and one C region, μ or ω. We have characterized eight distinct Ig miniloci encoding the nurse shark ω H chain. Each cluster consists of VH, D, and JH segments and six to eight C domain exons. Two interspersed secretory exons, in addition to the 3'-most C exon with tailpiece, provide the gene cluster with the ability to generate at least six secreted isoforms that differ as to polypeptide length and C domain combination. All clusters appear to be functional, as judged by the capability for rearrangement and absence of defects in the deduced amino acid sequence. We previously showed that IgW VDJ can perform isotype switching to μ C regions; in this study, we found that switching also occurs between ω clusters. Thus, C region diversification for any IgW VDJ can take place at the DNA level by switching to other ω or μ C regions, as well as by RNA processing to generate different C isoforms. The wide array of pathogens recognized by Abs requires different disposal pathways, and our findings demonstrate complex and unique pathways for C effector function diversity that evolved independently in cartilaginous fishes.

  18. C. albicans Growth, Transition, Biofilm Formation, and Gene Expression Modulation by Antimicrobial Decapeptide KSL-W

    DTIC Science & Technology

    2013-11-07

    Simon Theberge1, Abdelhabib Semlali1,2, Abdullah Alamri1, Kai P Leung3 and Mahmoud Rouabhia1* Abstract Background: Antimicrobial peptides have been the... peptides , including KSL-W (KKVVFWVKFK-NH2), for potential clinical use. Because this peptide displays antimicrobial activity against bacteria, we sought...the efficacy of KSL-W against C. albicans and its potential use as an antifungal therapy. Keywords: Antimicrobial peptide , KSL-W, C. albicans, Growth

  19. w4CSeq: software and web application to analyze 4C-seq data.

    PubMed

    Cai, Mingyang; Gao, Fan; Lu, Wange; Wang, Kai

    2016-11-01

    Circularized Chromosome Conformation Capture followed by deep sequencing (4C-Seq) is a powerful technique to identify genome-wide partners interacting with a pre-specified genomic locus. Here, we present a computational and statistical approach to analyze 4C-Seq data generated from both enzyme digestion and sonication fragmentation-based methods. We implemented a command line software tool and a web interface called w4CSeq, which takes in the raw 4C sequencing data (FASTQ files) as input, performs automated statistical analysis and presents results in a user-friendly manner. Besides providing users with the list of candidate interacting sites/regions, w4CSeq generates figures showing genome-wide distribution of interacting regions, and sketches the enrichment of key features such as TSSs, TTSs, CpG sites and DNA replication timing around 4C sites. Users can establish their own web server by downloading source codes at https://github.com/WGLab/w4CSeq Additionally, a demo web server is available at http://w4cseq.wglab.org CONTACT: kaiwang@usc.edu or wangelu@usc.eduSupplementary information: Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  20. MicroRNA-320 family is downregulated in colorectal adenoma and affects tumor proliferation by targeting CDK6.

    PubMed

    Tadano, Toshihiro; Kakuta, Yoichi; Hamada, Shin; Shimodaira, Yosuke; Kuroha, Masatake; Kawakami, Yoko; Kimura, Tomoya; Shiga, Hisashi; Endo, Katsuya; Masamune, Atsushi; Takahashi, Seiichi; Kinouchi, Yoshitaka; Shimosegawa, Tooru

    2016-07-15

    To investigate the microRNA (miRNA) expression during histological progression from colorectal normal mucosa through adenoma to carcinoma within a lesion. Using microarray, the sequential changes in miRNA expression profiles were compared in colonic lesions from matched samples; histologically, non-neoplastic mucosa, adenoma, and submucosal invasive carcinoma were microdissected from a tissue sample. Cell proliferation assay was performed to observe the effect of miRNA, and its target genes were predicted using bioinformatics approaches and the expression profile of SW480 transfected with the miRNA mimics. mRNA and protein levels of the target gene in colon cancer cell lines with a mimic control or miRNA mimics were measured using qRT-PCR and Western blotting. The expression levels of miRNA and target gene in colorectal tissue samples were also measured. Microarray analysis identified that the miR-320 family, including miR-320a, miR-320b, miR-320c, miR-320d and miR-320e, were differentially expressed in adenoma and submucosal invasive carcinoma. The miR-320 family, which inhibits cell proliferation, is frequently downregulated in colorectal adenoma and submucosal invasive carcinoma tissues. Seven genes including CDK6 were identified to be common in the results of gene expression array and bioinformatics analyses performed to find the target gene of the miR-320 family. We confirmed that mRNA and protein levels of CDK6 were significantly suppressed in colon cancer cell lines with miR-320 family mimics. CDK6 expression was found to increase from non-neoplastic mucosa through adenoma to submucosal invasive carcinoma tissues and showed an inverse correlation with miR-320 family expression. MiR-320 family affects colorectal tumor proliferation by targeting CDK6, plays important role in its growth, and is considered to be a biomarker for its early detection.