Sample records for wa-like genotype constellation

  1. Upsurge and spread of G3 rotaviruses in Eastern India (2014-2016): Full genome analyses reveals heterogeneity within Wa-like genomic constellation.

    PubMed

    Banerjee, Anindita; Lo, Mahadeb; Indwar, Pallavi; Deb, Alok K; Das, Santasabuj; Manna, Byomkesh; Dutta, Shanta; Bhadra, Uchhal K; Bhattacharya, Mala; Okamoto, Keinosuke; Chawla-Sarkar, Mamta

    2018-05-26

    Advent of new strains and shift in predominantly circulating genotypes are characteristics of group- A rotavirus (RVA), one of the major causes of childhood gastroenteritis. During diarrheal disease surveillance at Kolkata, India (2014-2016), a shift in circulating RVA strains from G1P[8] to G3P[8] was seen. Stool samples from children (n = 3048) with acute gastroenteritis were tested of which 38.7% were RVA positive. G1 was the predominant strain (65.3%) in 2014-2015 whereas in late 2015 and 2016, G3 became the preponderant strain (44.6%). In the past decade G3 strains were not observed in this region, we conducted whole genome sequencing of representative strains to gain insight into the phenomenon of emergence and genetic constellation of these circulating human G3 strains. The analyses revealed intergenogroup reassortment in G3P[4] strains (among Wa and DS-1-like genogroup) whereas G3P[8] strains were authentic Wa-like. Phylogenetic analysis revealed Kolkata G3 strains as polymorphic and thus they formed two sub-clusters due to antigenic differences in their VP7 protein. One of the sub-clusters had the wild-type threonine at 87 amino acid position while another sub-cluster had an isoleucine mutation. Presence of additional N-linked glycosylation site at amino acid 283 of VP7 glycoprotein suggests that the major neutralizing epitope on the VP7 (G3) of RotaTeq vaccine differs from the currently circulating G3 strains. The study is important as efficiency of rotavirus vaccine depends on the circulating heterogeneous genotype constellations. Continuous monitoring of circulating RVA strains in endemic settings like India is therefore important in pre- and post-vaccination period to monitor the emergence of new reassortant genotypes in addition to assessing vaccine efficacy. Copyright © 2018. Published by Elsevier B.V.

  2. Distinguishing the genotype 1 genes and proteins of human Wa-like rotaviruses vs. porcine rotaviruses

    PubMed Central

    Silva, Fernanda D.F.; Gregori, F.; McDonald, Sarah M.

    2016-01-01

    Group A rotaviruses (RVAs) are 11-segmented, double-stranded RNA viruses and important causes of gastroenteritis in the young of many animal species. Previous studies have suggested that human Wa-like RVAs share a close evolutionary relationship with porcine RVAs. Specifically, the VP1-VP3 and NSP2-5/6 genes of these viruses are usually classified as genotype 1 with >81% nucleotide sequence identity. Yet, it remains unknown whether the genotype 1 genes and proteins of human Wa-like strains are distinguishable from those of porcine strains. To investigate this, we performed comprehensive bioinformatic analyses using all known genotype 1 gene sequences. The RVAs analyzed represent wildtype strains isolated from humans or pigs at various geographical locations during the years of 2004–2013, including 11 newly-sequenced porcine RVAs from Brazil. We also analyzed archival strains that were isolated during the years of 1977–1992 as well as atypical strains involved in inter-species transmission between humans and pigs. We found that, in general, the genotype 1 genes of typical modern human Wa-like RVAs clustered together in phylogenetic trees and were separate from those of typical modern porcine RVAs. The only exception was for the NSP5/6 gene, which showed no host-specific phylogenetic clustering. Using amino acid sequence alignments, we identified 34 positions that differentiated the VP1-VP3, NSP2, and NSP3 genotype 1 proteins of typical modern human Wa-like RVAs versus typical modern porcine RVAs and documented how these positions vary in the archival/unusual isolates. No host-specific amino acid positions were identified for NSP4, NSP5, or NSP6. Altogether, the results of this study support the notion that human Wa-like RVAs and porcine RVAs are evolutionarily related, but indicate that some of their genotype 1 genes and proteins have diverged over time possibly as a reflection of sequestered replication and protein co-adaptation in their respective hosts. PMID

  3. Group A Human Rotavirus Genomics: Evidence that Gene Constellations Are Influenced by Viral Protein Interactions▿ †

    PubMed Central

    Heiman, Erica M.; McDonald, Sarah M.; Barro, Mario; Taraporewala, Zenobia F.; Bar-Magen, Tamara; Patton, John T.

    2008-01-01

    Group A human rotaviruses (HRVs) are the major cause of severe viral gastroenteritis in infants and young children. To gain insight into the level of genetic variation among HRVs, we determined the genome sequences for 10 strains belonging to different VP7 serotypes (G types). The HRVs chosen for this study, D, DS-1, P, ST3, IAL28, Se584, 69M, WI61, A64, and L26, were isolated from infected persons and adapted to cell culture to use as serotype references. Our sequencing results revealed that most of the individual proteins from each HRV belong to one of three genotypes (1, 2, or 3) based on their similarities to proteins of genogroup strains (Wa, DS-1, or AU-1, respectively). Strains D, P, ST3, IAL28, and WI61 encode genotype 1 (Wa-like) proteins, whereas strains DS-1 and 69M encode genotype 2 (DS-1-like) proteins. Of the 10 HRVs sequenced, 3 of them (Se584, A64, and L26) encode proteins belonging to more than one genotype, indicating that they are intergenogroup reassortants. We used amino acid sequence alignments to identify residues that distinguish proteins belonging to HRV genotype 1, 2, or 3. These genotype-specific changes cluster in definitive regions within each viral protein, many of which are sites of known protein-protein interactions. For the intermediate viral capsid protein (VP6), the changes map onto the atomic structure at the VP2-VP6, VP4-VP6, and VP7-VP6 interfaces. The results of this study provide evidence that group A HRV gene constellations exist and may be influenced by interactions among viral proteins during replication. PMID:18786998

  4. G1P[8] species A rotavirus over 27 years--pre- and post-vaccination eras--in Brazil: full genomic constellation analysis and no evidence for selection pressure by Rotarix® vaccine.

    PubMed

    da Silva, Marcelle Figueira Marques; Rose, Tatiana Lundgren; Gómez, Mariela Martínez; Carvalho-Costa, Filipe Anibal; Fialho, Alexandre Madi; de Assis, Rosane Maria Santos; de Andrade, Juliana da Silva Ribeiro; Volotão, Eduardo de Mello; Leite, José Paulo Gagliardi

    2015-03-01

    Epidemiological data on species A rotavirus (RVA) infections have demonstrated the genetic diversity of strains circulating worldwide. Many G and P genotype combinations have been described over the years, varying regionally and temporally, especially in developing countries. However, the most common G and P genotype combinations identified in RVA human strains worldwide are G1P[8], G2P[4], G3P[8], G4P[8] and G9P[8]. RVA genotype G1P[8] strains are responsible for more than 50% of child infections worldwide and component of the two vaccines (Rotarix® [RV1] and RotaTeq® [RV5]) licensed globally. For a better understanding of the evolutionary mechanisms of this genotype in Brazil, phylogenetic analyses based on the 11 RVA genome segments (genomic constellation) from 90 G1P[8] RVA strains collected in two eras - (i) pre-vaccination with RV1 (1996-February 2006); (ii) post-vaccination (March 2006-2013) - in different Brazilian states were performed. The results showed the Wa-like genomic constellation of the Brazilian G1P[8] strains with a I1-R1-C1-M1-A1-N1-T1-E1-H1 specificity, except for two strains (rj14055-07 and ba19030-10) that belong to a I1-R1-C1-M1-A1-N1-T3-E1-H1 genomic constellation, evidencing the occurrence of reassortment (Wa-like×AU-1-like) of the NSP3 gene. Reassortment events were also demonstrated between Brazilian G1P[8] strains and the RV1 vaccine strain in some genes in vaccinated and unvaccinated children. VP7 and VP8* antigenic site analysis showed that the amino acid substitutions observed in samples collected after the introduction of RV1 in Brazil were already detected in samples collected in the 1980s and 1990s, suggesting that mass Brazilian RV1 vaccination had no impact on the diversity observed inside antigenic sites for these two proteins. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Complete molecular genome analyses of equine rotavirus A strains from different continents reveal several novel genotypes and a largely conserved genotype constellation.

    PubMed

    Matthijnssens, Jelle; Miño, Samuel; Papp, Hajnalka; Potgieter, Christiaan; Novo, Luis; Heylen, Elisabeth; Zeller, Mark; Garaicoechea, Lorena; Badaracco, Alejandra; Lengyel, György; Kisfali, Péter; Cullinane, Ann; Collins, P J; Ciarlet, Max; O'Shea, Helen; Parreño, Viviana; Bányai, Krisztián; Barrandeguy, María; Van Ranst, Marc

    2012-04-01

    In this study, the complete genome sequences of seven equine group A rotavirus (RVA) strains (RVA/Horse-tc/GBR/L338/1991/G13P[18], RVA/Horse-wt/IRL/03V04954/2003/G3P[12] and RVA/Horse-wt/IRL/04V2024/2004/G14P[12] from Europe; RVA/Horse-wt/ARG/E30/1993/G3P[12], RVA/Horse-wt/ARG/E403/2006/G14P[12] and RVA/Horse-wt/ARG/E4040/2008/G14P[12] from Argentina; and RVA/Horse-wt/ZAF/EqRV-SA1/2006/G14P[12] from South Africa) were determined. Multiple novel genotypes were identified and genotype numbers were assigned by the Rotavirus Classification Working Group: R9 (VP1), C9 (VP2), N9 (NSP2), T12 (NSP3), E14 (NSP4), and H7 and H11 (NSP5). The genotype constellation of L338 was unique: G13-P[18]-I6-R9-C9-M6-A6-N9-T12-E14-H11. The six remaining equine RVA strains showed a largely conserved genotype constellation: G3/G14-P[12]-I2/I6-R2-C2-M3-A10-N2-T3-E2/E12-H7, which is highly divergent from other known non-equine RVA genotype constellations. Phylogenetic analyses revealed that the sequences of these equine RVA strains are related distantly to non-equine RVA strains, and that at least three lineages exist within equine RVA strains. A small number of reassortment events were observed. Interestingly, the three RVA strains from Argentina possessed the E12 genotype, whereas the three RVA strains from Ireland and South Africa possessed the E2 genotype. The unusual E12 genotype has until now only been described in Argentina among RVA strains collected from guanaco, cattle and horses, suggesting geographical isolation of this NSP4 genotype. This conserved genetic configuration of equine RVA strains could be useful for future vaccine development or improvement of currently used equine RVA vaccines.

  6. Detection of uncommon G3P[3] rotavirus A (RVA) strain in rat possessing a human RVA-like VP6 and a novel NSP2 genotype.

    PubMed

    Ianiro, Giovanni; Di Bartolo, Ilaria; De Sabato, Luca; Pampiglione, Guglielmo; Ruggeri, Franco M; Ostanello, Fabio

    2017-09-01

    Rotavirus is one of the leading causes of acute gastroenteritis in infants and young children. RVAs infect not only humans but also a wide range of mammals including rats, which represent a reservoir of several other zoonotic pathogens. Due to the segmented nature of the RVA genome, animal RVA strains can easily adapt to the human host by reassortment with co-infecting human viruses. This study aims to detect and characterize RVA in the intestinal content of Italian sinantropic rats (Rattus rattus). Out of 40 samples examined following molecular approach, one resulted positive for RVA. The molecular characterization of VP1-4, 6 and 7, and NSP1-5 genes by sequencing revealed the genomic constellation G3-P[3]-I1-R11-C11-M10-A22-N18-T14-E18-H13. This uncommon genomic combination includes: the VP1-4,VP7, the NSP1, 3, 4 and 5 gene segments, closely related to those of RVA from rodents, the N18 novel genotype established for the NSP2 gene segment and the human Wa-like VP6 gene, suggesting interspecies reassortment. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Kilohoku Ho`okele Wa`a--- Na `Ohana Hoku `Eha (The Astronomy of the Hawaiian Navigators--- The Four Star Families)

    NASA Astrophysics Data System (ADS)

    Slater, Stephanie; Slater, Timothy F.; Baybayan, Kalepa C.

    2016-01-01

    This paper documents the complete modern Hawaiian navigational full-sky. Over eight years of field notes, observations, and interviews with cultural leaders, historians, and ho`okele wa`a (navigators) were used to construct and validate Kilohoku Ho`okele Wa`a, the Astronomy of the Hawaiian Navigators. In contrast to the various historical sky maps designed by different practitioners and local groups in pre-colonial times, this sky-map depicts the four whole-sky constellations used by present day wayfinders. Designed by a loosely bound group of cultural leaders and navigators as a tool to use in modern non-instrumental navigation, Kilohoku Ho`okele Wa`a is a pragmatic fusion of ancient Hawaiian tradition, traditions of greater Polynesia, and modern-day Indigenous cultural forces. Like a very small number of cultures who use the sky for non-instrumental navigation, the ho`okele wa`a conceive of each season's visible sky as a whole image, using a single constellation that stretches from the northern to the southern horizon as a tool that facilitates direction finding in skies that are often very cloudy, and that chunks the sky into sections that decrease the cognitive load placed on the navigator. Moving through the seasons, beginning in Winter, Na `Ohana Hoku `Eha (The Four Star Families) are Kekaomakali`I (The Bailer), Kaiwikuamo`o (The Backbone), Manaiakalani (The Fishhook), and Kalupekawelo (The Kite). The whole-sky character of each of the four "star families," combines with that star family's mo`olelo (purposeful story) to further facilitate navigation, employing the emotional component of moral and familial associations to enhance memorization and to provide wayfinders with encouragement on their long journeys.

  8. Distinct genotype distribution and haplotype profiles in MDR1 gene among Chinese Han, Bai, Wa and Tibetan ethnic groups.

    PubMed

    Lai, Yong; Huang, Min; Li, Hui; Wang, Xue-Ding; Li, Jia-Li

    2012-11-01

    P-Glycoprotein (P-gp, encoded by MDR1 gene) plays an important role in determining bioavailability and pharmacologic effects of many drugs. There is increasing evidence that P-gp activity may be genetically determined. In this study, we investigated the genotype distribution and the haplotype profiles of MDR1 gene in Chinese Han, Bai, Wa and Tibetan subjects. Much lower frequencies of the 1236T allele and the 2677T allele were found in Wa subjects than those in other three ethnic groups, while the 2677A allele was found about 6-fold more frequently in Han subjects than in subjects of other three ethnic groups. The Han, Bai and Tibetan subjects share the same three predominant haplotypes (T-T-T, T-G-C and C-G-C), and T-T-T is the highest and accounts for more than one third of the number of haplotypes in the subjects from each ethnic group. However, T-T-T was less common than T-G-C, T-G-T and C-G-C and occurring at only 13.8% in Wa subjects, furthermore, higher frequencies of T-G-T, C-T-C, C-G-T and C-T-T were observed in Wa subjects compared to those in other three ethnic groups. Frequencies of C-A-C and T-A-C in Han subjects were higher than those in other three ethnic groups. The findings of this study will be of some relevance in predicting MDR1 phenotype and pharmacokinetics as well as pharmacodynamic effects of many commonly used drugs that are P-gp substrates in these four Chinese ethnic groups.

  9. CONSTELL: NASA's Satellite Constellation Model

    NASA Technical Reports Server (NTRS)

    Theall, Jeffrey R.; Krisko, Paula H.; Opiela, John N.; McKay, Gordon A. (Technical Monitor)

    1999-01-01

    The CONSTELL program represents an initial effort by the orbital debris modeling group at NASA/JSC to address the particular issues and problems raised by the presence of LEO satellite constellations. It was designed to help NASA better understand the potential orbital debris consequences of having satellite constellations operating in the future in LEO. However, it could also be used by constellation planners to evaluate architecture or design alternatives that might lessen debris consequences for their constellation or lessen the debris effects on other users of space. CONSTELL is designed to perform debris environment projections rapidly so it can support parametric assessments involving either the constellations themselves or the background environment which represents non-constellation users of the space. The projections need to be calculated quickly because a number of projections are often required to adequately span the parameter space of interest. To this end CONSTELL uses the outputs of other NASA debris environment models as inputs, thus doing away with the need for time consuming upfront calculations. Specifically, CONSTELL uses EVOLVE or ORDEM96 debris spatial density results as its background environment, debris cloud snapshot templates to simulate debris cloud propagation, and time dependent orbit profiles of the intact non- functional constellation spacecraft and upper stages. In this paper the environmental consequences of the deployment of particular LEO satellite constellations using the CONSTELL model will be evaluated. Constellations that will undergo a parametric assessment will reflect realistic parameter values. Among other results the increase in loss rate of non-constellation spacecraft, the number of collisions involving constellation elements, and the replacement rate of constellation satellites as a result of debris impact will be presented.

  10. Simian Rotaviruses Possess Divergent Gene Constellations That Originated from Interspecies Transmission and Reassortment▿

    PubMed Central

    Matthijnssens, Jelle; Taraporewala, Zenobia F.; Yang, Hongyan; Rao, Shujing; Yuan, Lijuan; Cao, Dianjun; Hoshino, Yasutaka; Mertens, Peter P. C.; Carner, Gerry R.; McNeal, Monica; Sestak, Karol; Van Ranst, Marc; Patton, John T.

    2010-01-01

    Although few simian rotaviruses (RVs) have been isolated, such strains have been important for basic research and vaccine development. To explore the origins of simian RVs, the complete genome sequences of strains PTRV (G8P[1]), RRV (G3P[3]), and TUCH (G3P[24]) were determined. These data allowed the genotype constellations of each virus to be determined and the phylogenetic relationships of the simian strains with each other and with nonsimian RVs to be elucidated. The results indicate that PTRV was likely transmitted from a bovine or other ruminant into pig-tailed macaques (its host of origin), since its genes have genotypes and encode outer-capsid proteins similar to those of bovine RVs. In contrast, most of the genes of rhesus-macaque strains, RRV and TUCH, have genotypes more typical of canine-feline RVs. However, the sequences of the canine and/or feline (canine/feline)-like genes of RRV and TUCH are only distantly related to those of modern canine/feline RVs, indicating that any potential transmission of a progenitor of these viruses from a canine/feline host to a simian host was not recent. The remaining genes of RRV and TUCH appear to have originated through reassortment with bovine, human, or other RV strains. Finally, comparison of PTRV, RRV, and TUCH genes with those of the vervet-monkey RV SA11-H96 (G3P[2]) indicates that SA11-H96 shares little genetic similarity to other simian strains and likely has evolved independently. Collectively, our data indicate that simian RVs are of diverse ancestry with genome constellations that originated largely by interspecies transmission and reassortment with nonhuman animal RVs. PMID:19939934

  11. Methods and Apparatuses for Signaling with Geometric Constellations

    NASA Technical Reports Server (NTRS)

    Barsoum, Maged F. (Inventor); Jones, Christopher R. (Inventor)

    2018-01-01

    Communication systems are described that use signal constellations, which have unequally spaced (i.e. `geometrically` shaped) points. In many embodiments, the communication systems use specific geometric constellations that are capacity optimized at a specific SNR. In addition, ranges within which the constellation points of a capacity optimized constellation can be perturbed and are still likely to achieve a given percentage of the optimal capacity increase compared to a constellation that maximizes d.sub.min, are also described. Capacity measures that are used in the selection of the location of constellation points include, but are not limited to, parallel decode (PD) capacity and joint capacity.

  12. Methods and apparatuses for signaling with geometric constellations

    NASA Technical Reports Server (NTRS)

    Jones, Christopher R. (Inventor); Barsoum, Maged F. (Inventor)

    2012-01-01

    Communication systems are described that use signal constellations, which have unequally spaced (i.e. geometrically shaped) points. In many embodiments, the communication systems use specific geometric constellations that are capacity optimized at a specific SNR. In addition, ranges within which the constellation points of a capacity optimized constellation can be perturbed and are still likely to achieve a given percentage of the optimal capacity increase compared to a constellation that maximizes d.sub.min, are also described. Capacity measures that are used in the selection of the location of constellation points include, but are not limited to, parallel decode (PD) capacity and joint capacity.

  13. Association of vWA and TPOX Polymorphisms with Venous Thrombosis in Mexican Mestizos

    PubMed Central

    Meraz-Ríos, Marco Antonio; Majluf-Cruz, Abraham; Santana, Carla; Noris, Gino; Camacho-Mejorado, Rafael; Acosta-Saavedra, Leonor C.; Calderón-Aranda, Emma S.; Hernández-Juárez, Jesús; Magaña, Jonathan J.; Gómez, Rocío

    2014-01-01

    Objective. Venous thromboembolism (VTE) is a multifactorial disorder and, worldwide, the most important cause of morbidity and mortality. Genetic factors play a critical role in its aetiology. Microsatellites are the most important source of human genetic variation having more phenotypic effect than many single nucleotide polymorphisms. Hence, we evaluate a possible relationship between VTE and the genetic variants in von Willebrand factor, human alpha fibrinogen, and human thyroid peroxidase microsatellites to identify possible diagnostic markers. Methods. Genotypes were obtained from 177 patients with VTE and 531 nonrelated individuals using validated genotyping methods. The allelic frequencies were compared; Bayesian methods were used to correct population stratification to avoid spurious associations. Results. The vWA-18, TPOX-9, and TPOX-12 alleles were significantly associated with VTE. Moreover, subjects bearing the combination vWA-18/TPOX-12 loci exhibited doubled risk for VTE (95% CI = 1.02–3.64), whereas the combination vWA-18/TPOX-9 showed an OR = 10 (95% CI = 4.93–21.49). Conclusions. The vWA and TPOX microsatellites are good candidate biomarkers in venous thromboembolism diseases and could help to elucidate their origins. Additionally, these polymorphisms could become useful markers for genetic studies of VTE in the Mexican population; however, further studies should be done owing that this data only show preliminary evidence. PMID:25250329

  14. The Solar system.Stars and constellations

    NASA Astrophysics Data System (ADS)

    Horia Minda, Octavian

    2017-04-01

    It is important for students to understand what is in our Solar System. The Students need to know that there are other things besides the Earth, Sun and Moon in the solar sky. The students will learn about the other eight planets and a few other celestial objects like stars and constellations. Constellations are useful because they can help people to recognize stars in the sky. By looking for patterns, the stars and locations can be much easier to spot. The constellations had uses in ancient times. They were used to help keep track of the calendar. This was very important so that people knew when to plant and harvest crops. Another important use for constellations was navigation. By finding Ursa Minor it is fairly easy to spot the North Star (Polaris). Using the height of the North Star in the sky, navigators could figure out their latitude helping ships to travel across the oceans. Objective: 1. The students will be introduced to the origin of the stars they see at night. 2. They will learn that there are groups of stars called constellations. The students will individually create their own constellations. They will be given the chance to tell the class a small story explaining their constellation. Evaluation of Children: The children will be evaluated through the creation of their constellations and ability to work in groups on the computers.

  15. Constellation Coverage Analysis

    NASA Technical Reports Server (NTRS)

    Lo, Martin W. (Compiler)

    1997-01-01

    The design of satellite constellations requires an understanding of the dynamic global coverage provided by the constellations. Even for a small constellation with a simple circular orbit propagator, the combinatorial nature of the analysis frequently renders the problem intractable. Particularly for the initial design phase where the orbital parameters are still fluid and undetermined, the coverage information is crucial to evaluate the performance of the constellation design. We have developed a fast and simple algorithm for determining the global constellation coverage dynamically using image processing techniques. This approach provides a fast, powerful and simple method for the analysis of global constellation coverage.

  16. Tethered constellations

    NASA Technical Reports Server (NTRS)

    Lorenzini, E.

    1986-01-01

    The studies that have been carried out on Tethered Constellations are briefly addressed. A definition of a tethered constellation is any number of masses/platforms greater that two connected by tethers in a stable configuration. Configurations and stability constraints are reviewed. Conclusions reached are: (1) The 1-D, horizontal, passively stabilized constellations have been ruled out; (2) Fishbone constellations have been also ruled out; (3) Alternative stable 2-D configurations have been devised such as the quadrangular configuration stabilized by electrodynamic forces (ESC), the quadrangular configuration stabilized by differential air drag (DSC), and the pseudo elliptical configuration stabilized by electrodynamic forces (PEC). Typical dimensions for these constellations are 10 km (horizontal) by 20 km (vertical) with balloon diameters around 100 m in the case of a DSC and a power consumption around 7 KW for an ESC or PEC.

  17. Capacity Maximizing Constellations

    NASA Technical Reports Server (NTRS)

    Barsoum, Maged; Jones, Christopher

    2010-01-01

    Some non-traditional signal constellations have been proposed for transmission of data over the Additive White Gaussian Noise (AWGN) channel using such channel-capacity-approaching codes as low-density parity-check (LDPC) or turbo codes. Computational simulations have shown performance gains of more than 1 dB over traditional constellations. These gains could be translated to bandwidth- efficient communications, variously, over longer distances, using less power, or using smaller antennas. The proposed constellations have been used in a bit-interleaved coded modulation system employing state-ofthe-art LDPC codes. In computational simulations, these constellations were shown to afford performance gains over traditional constellations as predicted by the gap between the parallel decoding capacity of the constellations and the Gaussian capacity

  18. Commanding Constellations (Pipeline Architecture)

    NASA Technical Reports Server (NTRS)

    Ray, Tim; Condron, Jeff

    2003-01-01

    Providing ground command software for constellations of spacecraft is a challenging problem. Reliable command delivery requires a feedback loop; for a constellation there will likely be an independent feedback loop for each constellation member. Each command must be sent via the proper Ground Station, which may change from one contact to the next (and may be different for different members). Dynamic configuration of the ground command software is usually required (e.g. directives to configure each member's feedback loop and assign the appropriate Ground Station). For testing purposes, there must be a way to insert command data at any level in the protocol stack. The Pipeline architecture described in this paper can support all these capabilities with a sequence of software modules (the pipeline), and a single self-identifying message format (for all types of command data and configuration directives). The Pipeline architecture is quite simple, yet it can solve some complex problems. The resulting solutions are conceptually simple, and therefore, reliable. They are also modular, and therefore, easy to distribute and extend. We first used the Pipeline architecture to design a CCSDS (Consultative Committee for Space Data Systems) Ground Telecommand system (to command one spacecraft at a time with a fixed Ground Station interface). This pipeline was later extended to include gateways to any of several Ground Stations. The resulting pipeline was then extended to handle a small constellation of spacecraft. The use of the Pipeline architecture allowed us to easily handle the increasing complexity. This paper will describe the Pipeline architecture, show how it was used to solve each of the above commanding situations, and how it can easily be extended to handle larger constellations.

  19. Whole genome analysis of selected human and animal rotaviruses identified in Uganda from 2012 to 2014 reveals complex genome reassortment events between human, bovine, caprine and porcine strains.

    PubMed

    Bwogi, Josephine; Jere, Khuzwayo C; Karamagi, Charles; Byarugaba, Denis K; Namuwulya, Prossy; Baliraine, Frederick N; Desselberger, Ulrich; Iturriza-Gomara, Miren

    2017-01-01

    Rotaviruses of species A (RVA) are a common cause of diarrhoea in children and the young of various other mammals and birds worldwide. To investigate possible interspecies transmission of RVAs, whole genomes of 18 human and 6 domestic animal RVA strains identified in Uganda between 2012 and 2014 were sequenced using the Illumina HiSeq platform. The backbone of the human RVA strains had either a Wa- or a DS-1-like genetic constellation. One human strain was a Wa-like mono-reassortant containing a DS-1-like VP2 gene of possible animal origin. All eleven genes of one bovine RVA strain were closely related to those of human RVAs. One caprine strain had a mixed genotype backbone, suggesting that it emerged from multiple reassortment events involving different host species. The porcine RVA strains had mixed genotype backbones with possible multiple reassortant events with strains of human and bovine origin.Overall, whole genome characterisation of rotaviruses found in domestic animals in Uganda strongly suggested the presence of human-to animal RVA transmission, with concomitant circulation of multi-reassortant strains potentially derived from complex interspecies transmission events. However, whole genome data from the human RVA strains causing moderate and severe diarrhoea in under-fives in Uganda indicated that they were primarily transmitted from person-to-person.

  20. Methods and Apparatuses for Signaling with Geometric Constellations in a Raleigh Fading Channel

    NASA Technical Reports Server (NTRS)

    Jones, Christopher R. (Inventor); Barsoum, Maged F. (Inventor)

    2015-01-01

    Communication systems are described that use signal constellations, which have unequally spaced (i.e., `geometrically` shaped) points. In many embodiments, the communication systems use specific geometric constellations that are capacity optimized at a specific SNR (signal to noise ratio). In addition, ranges within which the constellation points of a capacity optimized constellation can be perturbed and are still likely to achieve a given percentage of the optimal capacity increase compared to a constellation that maximizes d (sub min) (i.e. minimum distance between constellations) are also described. Capacity measures that are used in the selection of the location of constellation points include, but are not limited to, parallel decode (PD) capacity and joint capacity.

  1. Methods and Apparatuses for Signaling with Geometric Constellations in a Raleigh Fading Channel

    NASA Technical Reports Server (NTRS)

    Barsoum, Maged F. (Inventor); Jones, Christopher R. (Inventor)

    2017-01-01

    Communication systems are described that use signal constellations, which have unequally spaced (i.e. `geometrically` shaped) points. In many embodiments, the communication systems use specific geometric constellations that are capacity optimized at a specific SNR, over the Raleigh fading channel. In addition, ranges within which the constellation points of a capacity optimized constellation can be perturbed and are still likely to achieve a given percentage of the optimal capacity increase compared to a constellation that maximizes d.sub.min, are also described. Capacity measures that are used in the selection of the location of constellation points include, but are not limited to, parallel decode (PD) capacity and joint capacity.

  2. Aquarius-Pisces Constellation Boundary Update

    NASA Astrophysics Data System (ADS)

    Durst, Steve

    2017-06-01

    Observation, mapping and study of Galaxy Stars has provided humanity direction, foundation, clarity and understanding through the ages.Human civilization advances itself using increasing intelligence and knowledge to develop tools and know how, the science of constellation star maps included: All that has been created by humanity, is to serve humanity.When people continue to use constellation star maps that no longer serve people effectively, the maps are updated, as is now the Aquarius-Pisces Constellation Boundary Update (APCBU), which marks 2000 as the year the Sun is in Aquarius at the vernal equinox.The 21st Century APCBU accounts for and incorporates science factors of precession, relativity and galacticity for professional astronomers, and social imperatives of increasing freedom, liberation and egalitarian culture for the 7.5 billion people of Earth.Twenty years into this first century of a new millennium and a new age is an effective time for an APCBU of such elegant simplicity that it changes less than 0.1% of the area of the IAU 1930 official constellation map, which marks 2597 about the year the Sun is in Aquarius at the time of the vernal equinox.The 21st Century APCBU results provide clarity and direction for humanity's next 2,000 years, if not 10,000 or 12,000 years, and advance the official astronomy / science start of the Aquarius Age -- long anticipated, desired, and imperative, especially in America -- by some 600 years.How much attention is increasingly focused on this region of the sky -- such as the recent discovery of 7 Earth-like worlds orbiting the Trappist-1 star in the Aquarius constellation -- will be an epochal 21st Century phenomenon of human science, society, and starlife.

  3. Constellation Lessons Learned Executive Summary

    NASA Technical Reports Server (NTRS)

    Thomas, L. Dale; Neubek, Deb

    2011-01-01

    This slide presentation reviews the lessons learned from the Constellation Program (CxP) and identified several factors that contributed to the inability of the CxP to meet the cost and schedule commitments. The review includes a significant section on the context in which the CxP operated since new programs are likely to experience the same constraints.

  4. Comparative In Vitro and In Vivo Studies of Porcine Rotavirus G9P[13] and Human Rotavirus Wa G1P[8

    PubMed Central

    Shao, Lulu; Fischer, David D.; Kandasamy, Sukumar; Rauf, Abdul; Langel, Stephanie N.; Wentworth, David E.; Stucker, Karla M.; Halpin, Rebecca A.; Lam, Ham Ching; Marthaler, Douglas

    2015-01-01

    ABSTRACT The changing epidemiology of group A rotavirus (RV) strains in humans and swine, including emerging G9 strains, poses new challenges to current vaccines. In this study, we comparatively assessed the pathogenesis of porcine RV (PRV) G9P[13] and evaluated the short-term cross-protection between this strain and human RV (HRV) Wa G1P[8] in gnotobiotic pigs. Complete genome sequencing demonstrated that PRV G9P[13] possessed a human-like G9 VP7 genotype but shared higher overall nucleotide identity with historic PRV strains. PRV G9P[13] induced longer rectal virus shedding and RV RNAemia in pigs than HRV Wa G1P[8] and generated complete short-term cross-protection in pigs challenged with HRV or PRV, whereas HRV Wa G1P[8] induced only partial protection against PRV challenge. Moreover, PRV G9P[13] replicated more extensively in porcine monocyte-derived dendritic cells (MoDCs) than did HRV Wa G1P[8]. Cross-protection was likely not dependent on serum virus-neutralizing (VN) antibodies, as the heterologous VN antibody titers in the sera of G9P[13]-inoculated pigs were low. Thus, our results suggest that heterologous protection by the current monovalent G1P[8] HRV vaccine against emerging G9 strains should be evaluated in clinical and experimental studies to prevent further dissemination of G9 strains. Differences in the pathogenesis of these two strains may be partially attributable to their variable abilities to replicate and persist in porcine immune cells, including dendritic cells (DCs). Additional studies are needed to evaluate the emerging G9 strains as potential vaccine candidates and to test the susceptibility of various immune cells to infection by G9 and other common HRV/PRV genotypes. IMPORTANCE The changing epidemiology of porcine and human group A rotaviruses (RVs), including emerging G9 strains, may compromise the efficacy of current vaccines. An understanding of the pathogenesis and genetic, immunological, and biological features of the new emerging

  5. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    Jeff Hanley, Constellation Program Manager, announces to NASA employees and members of the media the responsibilities of the NASA centers associated with the Constellation Program for robotic and human Moon and Mars exploration on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit: (NASA/Bill Ingalls)

  6. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    Jeff Hanley, Constellation Program Manager, right, listens to a question during a NASA Update outlining responsibilities of the NASA centers associated with the Constellation Program for robotic and human Moon and Mars exploration on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit: (NASA/Bill Ingalls)

  7. CarbonSat Constellation

    NASA Astrophysics Data System (ADS)

    Sun, Wei; Tobehn, Carsten; Ernst, Robert; Bovensmann, Heinrich; Buchwitz, Michael; Burrows, John P.; Notholt, John

    1 Carbon dioxide (CO2) and methane (CH4) are the most important manmade greenhouse gases (GHGs) which are driving global climate change. Currently, the CO2 measurements from the ground observing network are still the main sources of information but due to the limited number of measurement stations the coverage is limited. In addition, CO2 monitoring and trading is often based mainly on bottom-up calculations and an independent top down verification is limited due to the lack of global measurement data with local resolution. The first CO2 and CH4 mapping from SCIAMACHY on ENVISAT shows that satellites add important missing global information. Current GHG measurement satellites (GOSAT)are limited either in spatial or temporal resolution and coverage. These systems have to collect data over a year or even longer to produce global regional fluxes products. Conse-quently global, timely, higher spatial resolution and high accuracy measurement are required for: 1. A good understanding of the CO2 and CH4 sources and sinks for reliable climate predic-tion; and 2. Independent and transparent verification of accountable sources and sinks in supporting Kyoto and upcoming protocols The CarbonSat constellation idea comes out the trade off of resolution and swath width during CarbonSat mission definition studies. In response to the urgent need to support the Kyoto and upcoming protocols, a feasibility study has been carried out. The proposed solution is a constellation of five CarbonSat satellites in 614km LTAN 13:00, which is able to provide global, daily CO2 and CH4 measurement everywhere on the Earth with high spatial resolution 2 × 2 km and low uncertainty lt;2ppm (CO2) and lt;8ppb (CH4). The unique global daily measurement capability significantly increases the number of cloud free measurements, which enables more reliable services associated with reduced uncertainty, e.g. to 0.15ppm (CO2) per month in 10km and even more timely products. The CarbonSat Constellation in

  8. Armenian Names of Sky Constellations

    NASA Astrophysics Data System (ADS)

    Mickaelian, A. M.; Farmanyan, S. V.; Mikayelyan, A. A.

    2016-12-01

    The work is devoted to the correction and recovery of the Armenian names of the sky constellations, as they were forgotten or distorted during the Soviet years, mainly due to the translation from Russian. A total of 34 constellation names have been corrected. A brief overview of the history of the division of the sky into constellations and their naming is also given. At the end, the list of all 88 constellations is given with the names in Latin, English, Russian and Armenian.

  9. Interactions of the space debris environment with mega constellations-Using the example of the OneWeb constellation

    NASA Astrophysics Data System (ADS)

    Radtke, Jonas; Kebschull, Christopher; Stoll, Enrico

    2017-02-01

    Recently, several announcements have been published to deploy satellite constellations into Low Earth Orbit (LEO) containing several hundred to thousands of rather small sized objects. The purpose of these constellations is to provide a worldwide internet coverage, even to the remotest areas. Examples of these mega-constellations are one from SpaceX, which is announced to comprise of about 4000 satellites, the Norwegian STEAM network, which is told to contain 4257 satellites, and the OneWeb constellation, which forms one of the smaller constellations with 720 satellites. As example constellation, OneWeb has been chosen. From all announced constellation, OneWeb by far delivered most information, both in regards to constellation design and their plans to encounter space debris issues, which is the reason why it has been chosen for these analyses. In this paper, at first an overview of the planned OneWeb constellation setup is given. From this description, a mission life-cycle is deduced, splitting the complete orbital lifetime of the satellites into four phases. Following, using ESA-MASTER, for each of the mission phases the flux on both single constellations satellites and the complete constellation are performed and the collision probabilities are derived. The focus in this analysis is set on catastrophic collisions. This analysis is then varied parametrically for different operational altitudes of the constellation as well as different lifetimes with different assumptions for the success of post mission disposal (PMD). Following the to-be-expected mean number of collision avoidance manoeuvres during all active mission phases is performed using ARES from ESA's DRAMA tool suite. The same variations as during the flux analysis are considered. Lastly the characteristics of hypothetical OneWeb satellite fragmentation clouds, calculated using the NASA Breakup model, are described and the impact of collision clouds from OneWeb satellites on the constellation itself is

  10. Origins of the "Western" Constellations

    NASA Astrophysics Data System (ADS)

    Frank, Roslyn M.

    The development of the 48 Greek constellations is analyzed as a complex mixture of cognitive layers deriving from different cultural traditions and dating back to different epochs. The analysis begins with a discussion of the zodiacal constellations, goes on to discuss the stellar lore in Homer and Hesiod, and then examines several theories concerning the origins of the southern non-zodiacal constellations. It concludes with a commentary concerning the age and possible cultural significance of stars of the Great Bear constellation in light of ethnohistorical documentation, folklore, and beliefs related to European bear ceremonialism.

  11. Constellation Program Update

    NASA Image and Video Library

    2006-06-05

    Jeff Hanley, Constellation Program Manager, right, and Scott J. Horowitz, NASA Associate Administrator for Exploration Systems announce to NASA employees and members of the media the responsibilities of the NASA centers associated with the Constellation Program for robotic and human Moon and Mars exploration on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit: (NASA/Bill Ingalls)

  12. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    Scott J. Horowitz, NASA Associate Administrator for Exploration Systems, left, and Jeff Hanley, Constellation Program Manager, announce to NASA employees and members of the media the responsibilities of the NASA centers associated with the Constellation Program for robotic and human Moon and Mars exploration on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit: (NASA/Bill Ingalls)

  13. The CEOS/GEO Constellation Concept

    NASA Technical Reports Server (NTRS)

    Cramer, Bryant; Ungar, Stephen

    2007-01-01

    The Constellation concept was first proposed during a discussion at the 19th CEOS Plenary, in London, in November 2005. The first Paper of the Constellation Concept was presented at the CEOS Strategic Implementation Team meeting (SIT-18), in Frascati, in March 2006, and strongly endorsed by the CEOS Principals. The concept attempts to provide agencies with tools for implementation of the elements that have been previously discussed in international forums (GEO Work Plan, GCOS Implementation Plan). This provides a solid foundation from the community providing requirements. Though agency spending is governed by national requirements, CEOS seeks synergies among member agency programs to fulfil GEOSS requirements, defining guidelines and standards to help agencies to determine from the outset what can be achieved. The constellations concept will allow the development of a commonalties approach among different agencies. At the heart of the application of the Constellations concept is the definition of a series of standards (specific to each Constellation) - required to be satisfied for any mission to be included in the constellation - and a process of recognition/acceptance, whereby an agency applies to SIT to have one or more of its missions (ideally from the outset of planning) recognised as meeting the constellation standards and thereby satisfying the relevant user community needs.

  14. The elusive constellations of poverty.

    PubMed

    Breugelmans, Seger M; Plantinga, Arnoud; Zeelenberg, Marcel; Poluektova, Olga; Efremova, Maria

    2017-01-01

    Pepper & Nettle describe possible processes underlying what they call a behavioral constellation of deprivation (BCD). Although we are certain about the application of evolutionary models to our understanding of poverty, we are less certain about the utility of behavioral constellations. The empirical record on poverty-related behaviors is much more divergent and broad than such constellations suggest.

  15. 75 FR 41762 - Safety Zone; Annual Kennewick, WA, Columbia Unlimited Hydroplane Races, Kennewick, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ...-AA00 Safety Zone; Annual Kennewick, WA, Columbia Unlimited Hydroplane Races, Kennewick, WA AGENCY..., Columbia Unlimited Hydroplane Races'' also known as the Tri-City Water Follies Hydroplane Races. The safety... Association hosts annual hydroplane races on the Columbia River in Kennewick, Washington. The Association is...

  16. Constellation Program Press Conference

    NASA Image and Video Library

    2006-06-04

    Jeff Hanley, Constellation Program Manager, speaks during a press conference outlining specific center responsibilities associated with the Constellation Program for robotic and human Moon and Mars exploration, Monday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit (NASA/Bill Ingalls)

  17. Constellation of phase singularities in a speckle-like pattern for optical vortex metrology applied to biological kinematic analysis.

    PubMed

    Wang, Wei; Qiao, Yu; Ishijima, Reika; Yokozeki, Tomoaki; Honda, Daigo; Matsuda, Akihiro; Hanson, Steen G; Takeda, Mitsuo

    2008-09-01

    A novel technique for biological kinematic analysis is proposed that makes use of the pseudophase singularities in a complex signal generated from a speckle-like pattern. In addition to the information about the locations and the anisotropic core structures of the pseudophase singularities, we also detect the spatial structures of a cluster of phase singularities, which serves as a unique constellation characterizing the mutual position relation between the individual pseudophase singularities. Experimental results of in vivo measurements for a swimming fish along with its kinematic analysis are presented, which demonstrate the validity of the proposed technique.

  18. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    NASA Administrator Michael Griffin, left, Scott J. Horowitz, NASA Associate Administrator for Exploration Systems and Jeff Hanley, Constellation Program Manager, right, announce to NASA employees and members of the media the responsibilities of the NASA centers associated with the Constellation Program for robotic and human Moon and Mars exploration on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit: (NASA/Bill Ingalls)

  19. Emergence of Double- and Triple-Gene Reassortant G1P[8] Rotaviruses Possessing a DS-1-Like Backbone after Rotavirus Vaccine Introduction in Malawi.

    PubMed

    Jere, Khuzwayo C; Chaguza, Chrispin; Bar-Zeev, Naor; Lowe, Jenna; Peno, Chikondi; Kumwenda, Benjamin; Nakagomi, Osamu; Tate, Jacqueline E; Parashar, Umesh D; Heyderman, Robert S; French, Neil; Cunliffe, Nigel A; Iturriza-Gomara, Miren

    2018-02-01

    To combat the high burden of rotavirus gastroenteritis, multiple African countries have introduced rotavirus vaccines into their childhood immunization programs. Malawi incorporated a G1P[8] rotavirus vaccine (Rotarix) into its immunization schedule in 2012. Utilizing a surveillance platform of hospitalized rotavirus gastroenteritis cases, we examined the phylodynamics of G1P[8] rotavirus strains that circulated in Malawi before (1998 to 2012) and after (2013 to 2014) vaccine introduction. Analysis of whole genomes obtained through next-generation sequencing revealed that all randomly selected prevaccine G1P[8] strains sequenced ( n = 32) possessed a Wa-like genetic constellation, whereas postvaccine G1P[8] strains ( n = 18) had a DS-1-like constellation. Phylodynamic analyses indicated that postvaccine G1P[8] strains emerged through reassortment events between human Wa- and DS-1-like rotaviruses that circulated in Malawi from the 1990s and hence were classified as atypical DS-1-like reassortants. The time to the most recent common ancestor for G1P[8] strains was from 1981 to 1994; their evolutionary rates ranged from 9.7 × 10 -4 to 4.1 × 10 -3 nucleotide substitutions/site/year. Three distinct G1P[8] lineages chronologically replaced each other between 1998 and 2014. Genetic drift was the likely driver for lineage turnover in 2005, whereas replacement in 2013 was due to reassortment. Amino acid substitution within the outer glycoprotein VP7 of G1P[8] strains had no impact on the structural conformation of the antigenic regions, suggesting that it is unlikely that they would affect recognition by vaccine-induced neutralizing antibodies. While the emergence of DS-1-like G1P[8] rotavirus reassortants in Malawi was therefore likely due to natural genotype variation, vaccine effectiveness against such strains needs careful evaluation. IMPORTANCE The error-prone RNA-dependent RNA polymerase and the segmented RNA genome predispose rotaviruses to genetic mutation and

  20. Emergence of Double- and Triple-Gene Reassortant G1P[8] Rotaviruses Possessing a DS-1-Like Backbone after Rotavirus Vaccine Introduction in Malawi

    PubMed Central

    2017-01-01

    ABSTRACT To combat the high burden of rotavirus gastroenteritis, multiple African countries have introduced rotavirus vaccines into their childhood immunization programs. Malawi incorporated a G1P[8] rotavirus vaccine (Rotarix) into its immunization schedule in 2012. Utilizing a surveillance platform of hospitalized rotavirus gastroenteritis cases, we examined the phylodynamics of G1P[8] rotavirus strains that circulated in Malawi before (1998 to 2012) and after (2013 to 2014) vaccine introduction. Analysis of whole genomes obtained through next-generation sequencing revealed that all randomly selected prevaccine G1P[8] strains sequenced (n = 32) possessed a Wa-like genetic constellation, whereas postvaccine G1P[8] strains (n = 18) had a DS-1-like constellation. Phylodynamic analyses indicated that postvaccine G1P[8] strains emerged through reassortment events between human Wa- and DS-1-like rotaviruses that circulated in Malawi from the 1990s and hence were classified as atypical DS-1-like reassortants. The time to the most recent common ancestor for G1P[8] strains was from 1981 to 1994; their evolutionary rates ranged from 9.7 × 10−4 to 4.1 × 10−3 nucleotide substitutions/site/year. Three distinct G1P[8] lineages chronologically replaced each other between 1998 and 2014. Genetic drift was the likely driver for lineage turnover in 2005, whereas replacement in 2013 was due to reassortment. Amino acid substitution within the outer glycoprotein VP7 of G1P[8] strains had no impact on the structural conformation of the antigenic regions, suggesting that it is unlikely that they would affect recognition by vaccine-induced neutralizing antibodies. While the emergence of DS-1-like G1P[8] rotavirus reassortants in Malawi was therefore likely due to natural genotype variation, vaccine effectiveness against such strains needs careful evaluation. IMPORTANCE The error-prone RNA-dependent RNA polymerase and the segmented RNA genome predispose rotaviruses to genetic

  1. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    Jeff Hanley, Constellation Program Manager, right, announces to NASA employees and members of the media the responsibilities of the NASA centers associated with the Constellation Program for robotic and human Moon and Mars exploration on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Hanley is joined by Scott J. Horowitz, NASA Associate Administrator for Exploration Systems and NASA Administrator Michael Griffin, left. Photo Credit: (NASA/Bill Ingalls)

  2. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    NASA Administrator Michael Griffin, left, announces to NASA employees and members of the media the responsibilities of the NASA centers associated with the Constellation Program for robotic and human Moon and Mars exploration on Wednesday, June 5, 2006, at NASA Headquarters in Washington. He is joined by Scott J. Horowitz, NASA Associate Administrator for Exploration Systems and Jeff Hanley, Constellation Program Manager, right. Photo Credit: (NASA/Bill Ingalls)

  3. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    Scott J. Horowitz, NASA Associate Administrator for Exploration Systems, center, announces to NASA employees and members of the media the responsibilities of the NASA centers associated with the Constellation Program for robotic and human Moon and Mars exploration on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Horowitz was joined by NASA Administrator Michael Griffin, left, and Jeff Hanley, Constellation Program Manager. Photo Credit: (NASA/Bill Ingalls)

  4. Constellations: A New Paradigm for Earth Observations

    NASA Technical Reports Server (NTRS)

    Kelly, Angelita C.; Volz, Stephen M.; Yuhas, Cheryl L.; Case, Warren F.

    2009-01-01

    The last decade has seen a significant increase in the number and the capabilities of remote sensing satellites launched by the international community. A relatively new approach has been the launching of satellites into heterogeneous constellations. Constellations provide the scientists a capability to acquire science data, not only from specific instruments on a single satellite, but also from instruments on other satellites that fly in the same orbit. Initial results from the A-Train (especially following the CALIPSO/CloudSat launch) attest to the tremendous scientific value of constellation flying. This paper provides a history of the constellations (particularly the A-Train) and how the A-Train mission design was driven by science requirements. The A-Train has presented operational challenges which had not previously been encountered. Operations planning had to address not only how the satellites of each constellation operate safely together, but also how the two constellations fly in the same orbits without interfering with each other when commands are uplinked or data are downlinked to their respective ground stations. This paper discusses the benefits of joining an on-orbit constellation. When compared to a single, large satellite, a constellation infrastructure offers more than just the opportunities for coincidental science observations. For example, constellations reduce risks by distributing observing instruments among numerous satellites; in contrast, a failed launch or a system failure in a single satellite would lead to loss of all observations. Constellations allow for more focused, less complex satellites. Constellations distribute the development, testing, and operations costs among various agencies and organizations for example, the Morning and Afternoon Constellations involve several agencies within the U.S. and in other countries. Lastly, this paper addresses the need to plan for the long-term evolution of a constellation. Agencies need to have

  5. Constellation Program Press Conference

    NASA Image and Video Library

    2006-06-04

    Scott Horowitz, NASA Associate Administrator for Exploration Systems, left, looks on as Jeff Hanley, Constellation Program Manager, speaks during a press conference outlining specific center responsibilities associated with the Constellation Program for robotic and human Moon and Mars exploration, Monday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit (NASA/Bill Ingalls)

  6. Constellation Program Press Conference

    NASA Image and Video Library

    2006-06-04

    Scott Horowitz, NASA Associate Administrator for Exploration Systems, left, and Jeff Hanley, Constellation Program Manager, are seen during a press conference outlining specific center responsibilities associated with the Constellation Program for robotic and human Moon and Mars exploration, Monday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit (NASA/Bill Ingalls)

  7. Constellation Program Press Conference

    NASA Image and Video Library

    2006-06-04

    Scott Horowitz, NASA Associate Administrator for Exploration Systems, center, speaks as Jeff Hanley, Constellation Program Manager, right, looks on during a press conference outlining specific center responsibilities associated with the Constellation Program for robotic and human Moon and Mars exploration, Monday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit (NASA/Bill Ingalls)

  8. Constellation Program Press Conference

    NASA Image and Video Library

    2006-06-04

    NASA Administrator Michael Griffin, left, Scott Horowitz, NASA Associate Administrator for Exploration Systems and Jeff Hanley, Constellation Program Manager, right, are seen during a press conference outlining specific center responsibilities associated with the Constellation Program for robotic and human Moon and Mars exploration, Monday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit (NASA/Bill Ingalls)

  9. Constellation Program Press Conference

    NASA Image and Video Library

    2006-06-04

    Members of the media listen during a press conference with NASA Administrator Michael Griffin, Scott Horowitz, NASA Associate Administrator for Exploration Systems and Jeff Hanley, Constellation Program Manager, outlining specific center responsibilities associated with the Constellation Program for robotic and human Moon and Mars exploration, Monday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit (NASA/Bill Ingalls)

  10. Dynamics of tethered constellations in Earth orbit

    NASA Technical Reports Server (NTRS)

    Lorenzini, E.

    1986-01-01

    Topics covered include station keeping of single-axis and two-axis constellations; single-axis vertical constellations with low-g platform; single-axis vertical constellations with three masses; deployment strategy; and damping of vibrational modes.

  11. Constellation Program Press Conference

    NASA Image and Video Library

    2006-06-04

    Dean Acosta, NASA Deputy Assistant Administrator and Press Secretary, moderates a press conference with NASA Administrator Michael Griffin Scott Horowitz, NASA Associate Administrator for Exploration Systems and Jeff Hanley, Constellation Program Manager, outlining specific center responsibilities associated with the Constellation Program for robotic and human Moon and Mars exploration, Monday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit (NASA/Bill Ingalls)

  12. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    NASA Administrator Michael Griffin is seen through a television camera at a NASA Update announcing to NASA employees and members of the media the responsibilities of the NASA centers associated with the Constellation Program for robotic and human Moon and Mars exploration on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Griffin was joined by Scott J. Horowitz, NASA Associate Administrator for Exploration Systems and Jeff Hanley, Constellation Program Manager, right. Dean Acosta, NASA Deputy Assistant Administrator and Press Secretary, far left, moderates the program. Photo Credit: (NASA/Bill Ingalls)

  13. The CEOS constellation for land surface imaging

    USGS Publications Warehouse

    Bailey, G.B.; Berger, Marsha; Jeanjean, H.; Gallo, K.P.

    2007-01-01

    A constellation of satellites that routinely and frequently images the Earth's land surface in consistently calibrated wavelengths from the visible through the microwave and in spatial detail that ranges from sub-meter to hundreds of meters would offer enormous potential benefits to society. A well-designed and effectively operated land surface imaging satellite constellation could have great positive impact not only on the quality of life for citizens of all nations, but also on mankind's very ability to sustain life as we know it on this planet long into the future. The primary objective of the Committee on Earth Observation Satellites (CEOS) Land Surface Imaging (LSI) Constellation is to define standards (or guidelines) that describe optimal future LSI Constellation capabilities, characteristics, and practices. Standards defined for a LSI Constellation will be based on a thorough understanding of user requirements, and they will address at least three fundamental areas of the systems comprising a Land Surface Imaging Constellation: the space segments, the ground segments, and relevant policies and plans. Studies conducted by the LSI Constellation Study Team also will address current and shorter-term problems and issues facing the land remote sensing community today, such as seeking ways to work more cooperatively in the operation of existing land surface imaging systems and helping to accomplish tangible benefits to society through application of land surface image data acquired by existing systems. 2007 LSI Constellation studies are designed to establish initial international agreements, develop preliminary standards for a mid-resolution land surface imaging constellation, and contribute data to a global forest assessment.

  14. Enzootic genotype S of H9N2 avian influenza viruses donates internal genes to emerging zoonotic influenza viruses in China.

    PubMed

    Gu, Min; Chen, Hongzhi; Li, Qunhui; Huang, Junqing; Zhao, Mingjun; Gu, Xiaobing; Jiang, Kaijun; Wang, Xiaoquan; Peng, Daxin; Liu, Xiufan

    2014-12-05

    Avian influenza viruses of subtype H9N2 are widely prevalent in poultry in many Asian countries, and the segmented nature of the viral genome results in multiple distinct genotypes via reassortment. In this study, genetic evolution of H9N2 viruses circulating in eastern China during 2007-2013 was analyzed. The results showed that the diversity of the gene constellations generated six distinct genotypes, in which a novel genotype (S) bearing the backbone of A/chicken/Shanghai/F/98-like viruses by acquiring A/quail/Hong Kong/G1/97-like polymerase basic subunit 2 and matrix genes has gradually established its ecological niche and been consistently prevalent in chicken flocks in eastern China since its first detection in 2007. Furthermore, genotype S possessed the peculiarity to donate most of its gene segments to other emerging influenza A viruses in China, including the novel reassortant highly pathogenic avian influenza H5N2, the 2013 novel H7N7, H7N9 and the latest reassortant H10N8 viruses, with potential threat to poultry industry and human health. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Constellation Space Suit System Development Status

    NASA Technical Reports Server (NTRS)

    Ross, Amy; Aitchison, Lindsay; Daniel, Brian

    2007-01-01

    The Constellation Program has initiated the first new flight suit development project since the Extravehicular Mobility Unit (EMU) was developed for the Space Shuttle Program in the 1970s. The Constellation suit system represents a significant challenge to designers in that the system is required to address all space suit functions needed through all missions and mission phases. This is in marked contrast to the EMU, which was designed specifically for micro-gravity space walks. The Constellation suit system must serve in all of the following scenarios: launch, entry and abort crew survival; micro-gravity extravehicular activity (EVA); and lunar (1/6th-gravity) surface EVA. This paper discusses technical efforts performed from May 2006 through February 2007 for the Constellation space suit system pressure garment.

  16. Far East Scarlet-Like Fever Caused by a Few Related Genotypes of Yersinia pseudotuberculosis, Russia.

    PubMed

    Timchenko, Nelly F; Adgamov, Ruslan R; Popov, Alexander F; Psareva, Ekaterina K; Sobyanin, Konstantin A; Gintsburg, Alexander L; Ermolaeva, Svetlana A

    2016-03-01

    We used multivirulence locus sequence typing to analyze 68 Yersinia pseudotuberculosis isolates from patients in Russia during 1973-2014, including 41 isolates from patients with Far East scarlet-like fever. Four genotypes were found responsible, with 1 being especially prevalent. Evolutionary analysis suggests that epidemiologic advantages could cause this genotype's dominance.

  17. Constellation Program Press Conference

    NASA Image and Video Library

    2006-06-04

    NASA Administrator Michael Griffin, seated left, Scott Horowitz, NASA Associate Administrator for Exploration Systems and Jeff Hanley, Constellation Program Manager, right, are seen during a press conference outlining specific center responsibilities associated with the Constellation Program for robotic and human moon and Mars exploration, Monday, June 5, 2006, at NASA Headquarters in Washington. Dean Acosta, NASA Deputy Assistant Administrator and Press Secretary, far left, moderates the program. Photo Credit (NASA/Bill Ingalls)

  18. The Origin of Our Constellations.

    ERIC Educational Resources Information Center

    Ridpath, Ian

    1990-01-01

    Reviewed is the history of the naming of the constellations which appear in the sky. The roles of many ancient peoples through the astronomers of the eighteenth century up to the adoption of the official list of 88 constellations produced in 1922 by the International Astronomical Union are discussed. (CW)

  19. The 2-D lattice theory of Flower Constellations

    NASA Astrophysics Data System (ADS)

    Avendaño, Martín E.; Davis, Jeremy J.; Mortari, Daniele

    2013-08-01

    The 2-D lattice theory of Flower Constellations, generalizing Harmonic Flower Constellations (the symmetric subset of Flower Constellations) as well as the Walker/ Mozhaev constellations, is presented here. This theory is a new general framework to design symmetric constellations using a 2× 2 lattice matrix of integers or by its minimal representation, the Hermite normal form. From a geometrical point of view, the phasing of satellites is represented by a regular pattern (lattice) on a two-Dimensional torus. The 2-D lattice theory of Flower Constellations does not require any compatibility condition and uses a minimum set of integer parameters whose meaning are explored throughout the paper. This general minimum-parametrization framework allows us to obtain all symmetric distribution of satellites. Due to the J_2 effect this design framework is meant for circular orbits and for elliptical orbits at critical inclination, or to design elliptical constellations for the unperturbed Keplerian case.

  20. Virus-Like Particle Secretion and Genotype-Dependent Immunogenicity of Dengue Virus Serotype 2 DNA Vaccine

    PubMed Central

    Galula, Jedhan U.; Shen, Wen-Fan; Chuang, Shih-Te

    2014-01-01

    ABSTRACT Dengue virus (DENV), composed of four distinct serotypes, is the most important and rapidly emerging arthropod-borne pathogen and imposes substantial economic and public health burdens. We constructed candidate vaccines containing the DNA of five of the genotypes of dengue virus serotype 2 (DENV-2) and evaluated the immunogenicity, the neutralizing (Nt) activity of the elicited antibodies, and the protective efficacy elicited in mice immunized with the vaccine candidates. We observed a significant correlation between the level of in vitro virus-like particle secretion, the elicited antibody response, and the protective efficacy of the vaccines containing the DNA of the different DENV genotypes in immunized mice. However, higher total IgG antibody levels did not always translate into higher Nt antibodies against homologous and heterologous viruses. We also found that, in contrast to previous reports, more than 50% of total IgG targeted ectodomain III (EDIII) of the E protein, and a substantial fraction of this population was interdomain highly neutralizing flavivirus subgroup-cross-reactive antibodies, such as monoclonal antibody 1B7-5. In addition, the lack of a critical epitope(s) in the Sylvatic genotype virus recognized by interdomain antibodies could be the major cause of the poor protection of mice vaccinated with the Asian 1 genotype vaccine (pVD2-Asian 1) from lethal challenge with virus of the Sylvatic genotype. In conclusion, although the pVD2-Asian 1 vaccine was immunogenic, elicited sufficient titers of Nt antibodies against all DENV-2 genotypes, and provided 100% protection against challenge with virus of the homologous Asian 1 genotype and virus of the heterologous Cosmopolitan genotype, it is critical to monitor the potential emergence of Sylvatic genotype viruses, since vaccine candidates under development may not protect vaccinated humans from these viruses. IMPORTANCE Five genotype-specific dengue virus serotype 2 (DENV-2) DNA vaccine

  1. LIBRA-WA: a web application for ligand binding site detection and protein function recognition.

    PubMed

    Toti, Daniele; Viet Hung, Le; Tortosa, Valentina; Brandi, Valentina; Polticelli, Fabio

    2018-03-01

    Recently, LIBRA, a tool for active/ligand binding site prediction, was described. LIBRA's effectiveness was comparable to similar state-of-the-art tools; however, its scoring scheme, output presentation, dependence on local resources and overall convenience were amenable to improvements. To solve these issues, LIBRA-WA, a web application based on an improved LIBRA engine, has been developed, featuring a novel scoring scheme consistently improving LIBRA's performance, and a refined algorithm that can identify binding sites hosted at the interface between different subunits. LIBRA-WA also sports additional functionalities like ligand clustering and a completely redesigned interface for an easier analysis of the output. Extensive tests on 373 apoprotein structures indicate that LIBRA-WA is able to identify the biologically relevant ligand/ligand binding site in 357 cases (∼96%), with the correct prediction ranking first in 349 cases (∼98% of the latter, ∼94% of the total). The earlier stand-alone tool has also been updated and dubbed LIBRA+, by integrating LIBRA-WA's improved engine for cross-compatibility purposes. LIBRA-WA and LIBRA+ are available at: http://www.computationalbiology.it/software.html. polticel@uniroma3.it. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  2. VISTA - A Constellation for Real Time Regional Imaging

    NASA Astrophysics Data System (ADS)

    Meerman, Max; Boland, Lee; da Silva Curiel, Alex; Sweeting, Martin, , Sir

    2002-01-01

    The role of satellites in medium and high-resolution reconnaissance of the Earth's surface has been well demonstrated in recent years through missions such as Landsat, SPOT, IKONOS, ImageSat and Quickbird. The market for such data products is well served and likely to become more competitive with further very-high-resolution missions. Whereas commercial markets have concentrated on enhancing resolution, the small satellite sector has concentrated on reducing the cost of data products, and the development of systems providing niche services. One such EO requirement that can be well met by smaller satellites is the need for higher temporal resolution, as this typically requires a large number of satellites to operate as a constellation - thus far financially impractical using conventional EO satellites. Surrey is currently engaged in building its first constellation that will provide daily global coverage at moderate resolution (32-metre GSD and 600km swath) in three spectral bands. Targeted at providing timely quick-look data products for disaster mitigation and monitoring, the constellation comprises 7 satellites in a single orbital plane. Each satellite has a wide swath so that successive satellites progressively cover the entire globe in a single day. The Vista constellation takes this concept a step further, and is proposed for applications requiring near-continuous surveillance of regional activity. By introducing a multiple plane constellation of small Earth observation satellites, it is possible to monitor continuously selected regions anywhere on the globe. The paper describes the system trades and outlines the scope of the performance that could be obtained from such a system. A cost model illustrates that the balance between launch and space segment costs must be reached by considering suitable replacement strategies, and that the system is highly sensitive to requirement creep. Finally, it is shown that the use of cost effective, small satellites leads to

  3. Rotavirus Surveillance in Kisangani, the Democratic Republic of the Congo, Reveals a High Number of Unusual Genotypes and Gene Segments of Animal Origin in Non-Vaccinated Symptomatic Children

    PubMed Central

    Heylen, Elisabeth; Batoko Likele, Bibi; Zeller, Mark; Stevens, Stijn; De Coster, Sarah; Conceição-Neto, Nádia; Van Geet, Christel; Jacobs, Jan; Ngbonda, Dauly; Van Ranst, Marc; Matthijnssens, Jelle

    2014-01-01

    Group A rotavirus (RVA) infections form a major public health problem, especially in low-income countries like the Democratic Republic of the Congo (COD). However, limited data on RVA diversity is available from sub-Saharan Africa in general and the COD in particular. Therefore, the first aim of this study was to determine the genetic diversity of 99 RVAs detected during 2007–2010 in Kisangani, COD. The predominant G-type was G1 (39%) and the most predominant P-type was P[6] (53%). A total of eight different G/P-combinations were found: G1P[8] (28%), G8P[6] (26%), G2P[4] (14%), G12P[6] (13%), G1P[6] (11%), G9P[8] (4%), G4P[6] (2%) and G8P[4] (1%). The second aim of this study was to gain insight into the diversity of P[6] RVA strains in the COD. Therefore, we selected five P[6] RVA strains in combination with the G1, G4, G8 (2x) or G12 genotype for complete genome analysis. Complete genome analysis showed that the genetic background of the G1P[6] and G12P[6] strains was entirely composed of genotype 1 (Wa-like), while the segments of the two G8P[6] strains were identified as genotype 2 (DS-1-like). Interestingly, all four strains possessed a NSP4 gene of animal origin. The analyzed G4P[6] RVA strain was found to possess the unusual G4-P[6]-I1-R1-C1-M1-A1-N1-T7-E1-H1 constellation. Although the majority of its genes (if not all), were presumably of porcine origin, this strain was able to cause gastro-enteritis in humans. The high prevalence of unusual RVA strains in the COD highlights the need for continued surveillance of RVA diversity in the COD. These results also underline the importance of complete genetic characterization of RVA strains and indicate that reassortments and interspecies transmission among human and animal RVAs strains occur regularly. Based on these data, RVA vaccines will be challenged with a wide variety of different RVA strain types in the COD. PMID:24968018

  4. Best Practices for Operations of Satellite Constellations

    NASA Technical Reports Server (NTRS)

    Howard, Joseph; Oza, Dipak; Smith, Danford S.

    2006-01-01

    This paper presents the best practices used by several commercial and government operators of satellite constellations. These best practices were identified through a series of seminars and discussions held at NASA Goddard Space Flight Center (GSFC). The best practices are arrived through many years of experience and improvements made in the operations procedures and the operational systems with the primary drivers as mission safety and cost effectiveness. This paper discusses the operational aspects associated with how different organizations manage complexities of constellation operations. For the purposes of this paper, satellite constellations are groups of similar spacecraft with more than one spacecraft needed to fully accomplish the constellation's mission

  5. Launching Science: Science Opportunities Provided by NASA's Constellation System

    NASA Technical Reports Server (NTRS)

    2008-01-01

    mission concepts that could take advantage of Constellation s unique capabilities are likely to be prohibitively expensive. Several times in the past NASA has begun ambitious space science missions that ultimately proved too expensive for the agency to pursue. Examples include the Voyager-Mars mission and the Prometheus program and its Jupiter Icy Moons Orbiter spacecraft (both examples are discussed in Chapter 1). Finding: The scientific missions reviewed by the committee as appropriate for launch on an Ares V vehicle fall, with few exceptions, into the "flagship" class of missions. The preliminary cost estimates, based on mission concepts that at this time are not very detailed, indicate that the costs of many of the missions analyzed will be above $5 billion (in current dollars). The Ares V costs are not included in these estimates. All of the costs discussed in this report are presented in current-year (2008) dollars, not accounting for potential inflation that could occur between now and the decade in which these missions might be pursued. In general, preliminary cost estimates for proposed missions are, for many reasons, significantly lower than the final costs. Given the large cost estimates for many of the missions assessed in this report, the potentially large impacts on NASA's budget by many of these missions are readily apparent.

  6. Genotyping of Avian infectious bronchitis viruses in Iran (2015-2017) reveals domination of IS-1494 like virus.

    PubMed

    Modiri Hamadan, Amir; Ghalyanchilangeroudi, Arash; Hashemzadeh, Masoud; Hosseini, Hossein; Karimi, Vahid; Yahyaraeyat, Ramak; Najafi, Hamideh

    2017-08-15

    Avian infectious bronchitis virus (IBV) is causing major economic losses to the poultry industry. The analysis of the S1 gene has been used to determine IBV genotype. The aim of this study was genotyping of IBVs circulating among the Iranian broiler flocks in the period between 2015 to 2017. Trachea samples from 278 broiler flocks were collected from broiler farms in eight provinces of Iran. After Real-time RT-PCR, IBV-positive samples were further characterized based on S1 gene. The results of the Real-time RT-PCR showed that 52.16% of flocks were IBV positive. Four genotypes were detected and the frequency of occurrence rates of IS-1494-like, 793/B, QX and Massachusetts IBV genotypes were 70.34%, 19.31%, 7.58% and 2.75%, respectively. Sequence analysis revealed that nucleotide identities within IS-1494-like group ranged between 98.86-100%, while each of the QX, Massachusetts and 793/B groups were 98.05-100%, 98.20-100% and 93.29-100% respectively. These results show that the IS-1494-like IBV is the dominant IBV genotype in Iran. Proper control strategies are essential to overcoming the high frequency of occurrence of IS-1494-like IBV. The phylogenetic relationship of the strains with respect to different sequences and geographical regions displayed complexity and diversity. Further studies are needed and should include the isolation and full-length molecular characterization of IBV in Iran. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Automating Trend Analysis for Spacecraft Constellations

    NASA Technical Reports Server (NTRS)

    Davis, George; Cooter, Miranda; Updike, Clark; Carey, Everett; Mackey, Jennifer; Rykowski, Timothy; Powers, Edward I. (Technical Monitor)

    2001-01-01

    missions such as DRACO with the intent that mission operations costs be significantly reduced. The goal of the Constellation Spacecraft Trend Analysis Toolkit (CSTAT) project is to serve as the pathfinder for a fully automated trending system to support spacecraft constellations. The development approach to be taken is evolutionary. In the first year of the project, the intent is to significantly advance the state of the art in current trending systems through improved functionality and increased automation. In the second year, the intent is to add an expert system shell, likely through the adaptation of an existing commercial-off-the-shelf (COTS) or government-off-the-shelf (GOTS) tool to implement some level of the trending intelligence that humans currently provide in manual operations. In the third year, the intent is to infuse the resulting technology into a near-term constellation or formation-flying mission to test it and gain experience in automated trending. The lessons learned from the real missions operations experience will then be used to improve the system, and to ultimately incorporate it into a fully autonomous, closed-loop mission operations system that is truly capable of supporting large constellations. In this paper, the process of automating trend analysis for spacecraft constellations will be addressed. First, the results of a survey on automation in spacecraft mission operations in general, and in trending systems in particular will be presented to provide an overview of the current state of the art. Next, a rule-based model for implementing intelligent spacecraft subsystem trending will be then presented, followed by a survey of existing COTS/GOTS tools that could be adapted for implementing such a model. The baseline design and architecture of the CSTAT system will be presented. Finally, some results obtained from initial software tests and demonstrations will be presented.

  8. Sensor Webs to Constellations

    NASA Astrophysics Data System (ADS)

    Cole, M.

    2017-12-01

    Advanced technology plays a key role in enabling future Earth-observing missions needed for global monitoring and climate research. Rapid progress over the past decade and anticipated for the coming decades have diminished the size of some satellites while increasing the amount of data and required pace of integration and analysis. Sensor web developments provide correlations to constellations of smallsats. Reviewing current advances in sensor webs and requirements for constellations will improve planning, operations, and data management for future architectures of multiple satellites with a common mission goal.

  9. Global Coverage from Ad-Hoc Constellations in Rideshare Orbits

    NASA Technical Reports Server (NTRS)

    Ellis, Armin; Mercury, Michael; Brown, Shannon

    2012-01-01

    A promising area of small satellite development is in providing higher temporal resolution than larger satellites. Traditional constellations have required specific orbits and dedicated launch vehicles. In this paper we discuss an alternative architecture in which the individual elements of the constellation are launched as rideshare opportunities. We compare the coverage of such an ad-hoc constellation with more traditional constellations. Coverage analysis is based on actual historical data from rideshare opportunities. Our analysis includes ground coverage and temporal revisits for Polar, Tropics, Temperate, and Global regions, comparing ad-hoc and Walker constellation.

  10. Constellation Operations: Lessons Learned For Future Exploration

    NASA Technical Reports Server (NTRS)

    Kelly, Angelita C.; Case, Warren F.

    2006-01-01

    The Earth science community has long advocated placing numerous instruments in space to study the Earth and its environment. Space agencies from many countries have responded to this call with a wide range of orbiting satellites. Scientists also envisioned placing some satellites in constellations, to enable diverse remote sensing instruments to observe the same part of the Earth (or its atmosphere) at about the same time, thereby increasing the opportunities for coincident science observations. The Earth Science Afternoon Constellation is answering this call, but there have been unique challenges on the way to its deployment. Currently, the Afternoon Constellation is to comprise six satellites. Three are currently on orbit: NASA's Earth Observing System (EOS)-Aqua (2002) and EOS-Aura (2004), and CNES's Polarization & Anisotropy of Reflectances for Atmospheric Sciences coupled with Observations from a Lidar (PARASOL) (2004). Two more satellites, the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO) and Cloudsat, are to be jointly launched in late 2005, followed by the Orbiting Carbon Observatory (OCO) in 2008. The Afternoon Constellation is unlike most satellite constellations in that: 1) It is not a homogenous mix of identical satellites; rather it comprises several satellites with complementary observational capabilities; 2) The satellites are not spaced around the Earth to provide instantaneous, global coverage (as for a communications satellite constellation); rather they orbit in close proximity so observations occur at about the same time over approximately the same region; and 3) Lastly, the satellites are not managed and controlled by one organization; rather the list of organizations is diverse: CNES in France, NASA Centers at Goddard, Langley, and the Jet Propulsion Laboratory, and the US Air Force facility in New Mexico. The PARASOL launch and early orbit (L&EO) phase proved to be a learning experience for constellation members

  11. Autonomous interplanetary constellation design

    NASA Astrophysics Data System (ADS)

    Chow, Cornelius Channing, II

    According to NASA's integrated space technology roadmaps, space-based infrastructures are envisioned as necessary ingredients to a sustained effort in continuing space exploration. Whether it be for extra-terrestrial habitats, roving/cargo vehicles, or space tourism, autonomous space networks will provide a vital communications lifeline for both future robotic and human missions alike. Projecting that the Moon will be a bustling hub of activity within a few decades, a near-term opportunity for in-situ infrastructure development is within reach. This dissertation addresses the anticipated need for in-space infrastructure by investigating a general design methodology for autonomous interplanetary constellations; to illustrate the theory, this manuscript presents results from an application to the Earth-Moon neighborhood. The constellation design methodology is formulated as an optimization problem, involving a trajectory design step followed by a spacecraft placement sequence. Modeling the dynamics as a restricted 3-body problem, the investigated design space consists of families of periodic orbits which play host to the constellations, punctuated by arrangements of spacecraft autonomously guided by a navigation strategy called LiAISON (Linked Autonomous Interplanetary Satellite Orbit Navigation). Instead of more traditional exhaustive search methods, a numerical continuation approach is implemented to map the admissible configuration space. In particular, Keller's pseudo-arclength technique is used to follow folding/bifurcating solution manifolds, which are otherwise inaccessible with other parameter continuation schemes. A succinct characterization of the underlying structure of the local, as well as global, extrema is thus achievable with little a priori intuition of the solution space. Furthermore, the proposed design methodology offers benefits in computation speed plus the ability to handle mildly stochastic systems. An application of the constellation design

  12. A Case Study: Using Delmia at Kennedy Space Center to Support NASA's Constellation Program

    NASA Technical Reports Server (NTRS)

    Kickbusch, Tracey; Humeniuk, Bob

    2010-01-01

    The presentation examines the use of Delmia (Digital Enterprise Lean Manufacturing Interactive Application) for digital simulation in NASA's Constellation Program. Topics include an overview of the Kennedy Space Center (KSC) Design Visualization Group tasks, NASA's Constellation Program, Ares 1 ground processing preliminary design review, and challenges and how Delmia is used at KSC, Challenges include dealing with large data sets, creating and maintaining KSC's infrastructure, gathering customer requirements and meeting objectives, creating life-like simulations, and providing quick turn-around on varied products,

  13. Potential role of exoglucanase genes (WaEXG1 and WaEXG2) in the biocontrol activity of Wickerhamomyces anomalous

    USDA-ARS?s Scientific Manuscript database

    The use of yeasts, including Wickerhamomyces anomalus, as biocontrol agents against fungi responsible for postharvest diseases of fruits and vegetables has been investigated for the past two decades. Among a variety of killer mechanisms, the production of glucanases coded by the genes WaEXG1 and Wa...

  14. Full genome analysis of rotavirus G9P[8] strains identified in acute gastroenteritis cases reveals genetic diversity: Pune, western India.

    PubMed

    Tatte, Vaishali S; Chaphekar, Deepa; Gopalkrishna, Varanasi

    2017-08-01

    Group A rotaviruses (RVA) are the major enteric etiological agents of severe acute gastroenteritis among children globally. As G9 RVA now represents as one of the major human RVA genotypes, studies on full genome of this particular genotype are being carried out worldwide. So far, no such studies on G9P[8] RVAs have been reported from Pune, western part of India. Keeping in view of this, the study was undertaken to understand the degree of genetic diversity of the commonly circulating G9P[8] RVA strains. Rotavirus surveillance studies carried out earlier during the years 2009-2011 showed increase in the prevalence of G9P[8] RVAs. Representative G9P[8] RVA strains from the years 2009, 2010, and 2011 were selected for the study. In general, all the G9 RVA strains showed clustering in the globally circulating sublineage of the VP7 gene and showed nucleotide/amino acid identities of 96.8-99.7%/96.9-99.8% with global G9 RV strains. Full genome analysis, of all three RVAs in this study indicated Wa-like genotype constellation G9-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1. Within the strains nucleotide/amino acid divergence of 0.1-3.4%/0.0-4.1% was noted in all the RVA structural and non-structural genes. In conclusion, the present study highlights intra-genotypic variations throughout the RVA genome. The study further emphasizes the need for surveillance and analysis of the whole genomic constellation of the commonly circulating RVA strains of other regions in the country for understanding to a greater degree of the impact of rotavirus vaccination recently introduced in India. © 2017 Wiley Periodicals, Inc.

  15. 75 FR 51177 - Revocation of Class E Airspace; Eastsound, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ... airspace at Orcas Island Airport, Eastsound, WA. Controlled airspace already exists in the Eastsound, WA area that accommodates the safety and management of aircraft operations at Orcas Island Airport. DATES... Regulations (14 CFR) part 71 by removing Class E surface airspace at Orcas Island Airport, Eastsound, WA...

  16. Hidden topological constellations and polyvalent charges in chiral nematic droplets

    PubMed Central

    Posnjak, Gregor; Čopar, Simon; Muševič, Igor

    2017-01-01

    Topology has an increasingly important role in the physics of condensed matter, quantum systems, material science, photonics and biology, with spectacular realizations of topological concepts in liquid crystals. Here we report on long-lived hidden topological states in thermally quenched, chiral nematic droplets, formed from string-like, triangular and polyhedral constellations of monovalent and polyvalent singular point defects. These topological defects are regularly packed into a spherical liquid volume and stabilized by the elastic energy barrier due to the helical structure and confinement of the liquid crystal in the micro-sphere. We observe, for the first time, topological three-dimensional point defects of the quantized hedgehog charge q=−2, −3. These higher-charge defects act as ideal polyvalent artificial atoms, binding the defects into polyhedral constellations representing topological molecules. PMID:28220770

  17. Hidden topological constellations and polyvalent charges in chiral nematic droplets

    NASA Astrophysics Data System (ADS)

    Posnjak, Gregor; Čopar, Simon; Muševič, Igor

    2017-02-01

    Topology has an increasingly important role in the physics of condensed matter, quantum systems, material science, photonics and biology, with spectacular realizations of topological concepts in liquid crystals. Here we report on long-lived hidden topological states in thermally quenched, chiral nematic droplets, formed from string-like, triangular and polyhedral constellations of monovalent and polyvalent singular point defects. These topological defects are regularly packed into a spherical liquid volume and stabilized by the elastic energy barrier due to the helical structure and confinement of the liquid crystal in the micro-sphere. We observe, for the first time, topological three-dimensional point defects of the quantized hedgehog charge q=-2, -3. These higher-charge defects act as ideal polyvalent artificial atoms, binding the defects into polyhedral constellations representing topological molecules.

  18. 75 FR 24400 - National Maritime Week Tugboat Races, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... Maritime Week Tugboat Races, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of... Maritime Week Tugboat Races in Elliott Bay, WA on May 8, 2010. This action is necessary to ensure the... the Special Local Regulation for the annual National Maritime Week Tugboat Races, Seattle, WA in 33...

  19. Crater Constellation

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    (the Cup; abbrev. Crt, gen. Crateris; area 282 sq. deg.) A southern constellation which lies to the south-west of Virgo, and culminates at midnight in mid-March. It represents the cup of the god Apollo in Greek mythology (see Corvus). Its brightest stars were cataloged by Ptolemy (c. AD 100-175) in the Almagest....

  20. Space Technology 5 - A Successful Micro-Satellite Constellation Mission

    NASA Technical Reports Server (NTRS)

    Carlisle, Candace; Webb, Evan H.

    2007-01-01

    The Space Technology 5 (ST5) constellation of three micro-satellites was launched March 22, 2006. During the three-month flight demonstration phase, the ST5 team validated key technologies that will make future low-cost micro-sat constellations possible, demonstrated operability concepts for future micro-sat science constellation missions, and demonstrated the utility of a micro-satellite constellation to perform research-quality science. The ST5 mission was successfully completed in June 2006, demonstrating high-quality science and technology validation results.

  1. Methodology and Method and Apparatus for Signaling with Capacity Optimized Constellations

    NASA Technical Reports Server (NTRS)

    Barsoum, Maged F. (Inventor); Jones, Christopher R. (Inventor)

    2016-01-01

    Design Methodology and Method and Apparatus for Signaling with Capacity Optimized Constellation Abstract Communication systems are described that use geometrically PSK shaped constellations that have increased capacity compared to conventional PSK constellations operating within a similar SNR band. The geometrically shaped PSK constellation is optimized based upon parallel decoding capacity. In many embodiments, a capacity optimized geometrically shaped constellation can be used to replace a conventional constellation as part of a firmware upgrade to transmitters and receivers within a communication system. In a number of embodiments, the geometrically shaped constellation is optimized for an Additive White Gaussian Noise channel or a fading channel. In numerous embodiments, the communication uses adaptive rate encoding and the location of points within the geometrically shaped constellation changes as the code rate changes.

  2. Constellation Pharmacology: A new paradigm for drug discovery

    PubMed Central

    Schmidt, Eric W.; Olivera, Baldomero M.

    2015-01-01

    Constellation Pharmacology is a cell-based high-content phenotypic-screening platform that utilizes subtype-selective pharmacological agents to elucidate the cell-specific combinations (“constellations”) of key signaling proteins that define specific cell types. Heterogeneous populations of native cells, in which the different individual cell types have been identified and characterized, are the foundation for this screening platform. Constellation Pharmacology is useful for screening small molecules or for deconvoluting complex mixtures of biologically-active natural products. This platform has been used to purify natural products and discover their molecular mechanisms. In the on-going development of Constellation Pharmacology, there is a positive-feedback loop between the pharmacological characterization of cell types and screening for new drug candidates. As Constellation Pharmacology is used to discover compounds with novel targeting-selectivity profiles, those new compounds then further help to elucidate the constellations of specific cell types, thereby increasing the content of this high-content platform. PMID:25562646

  3. The NASA Constellation Program Procedure System

    NASA Technical Reports Server (NTRS)

    Phillips, Robert G.; Wang, Lui

    2010-01-01

    NASA has used procedures to describe activities to be performed onboard vehicles by astronaut crew and on the ground by flight controllers since Apollo. Starting with later Space Shuttle missions and the International Space Station, NASA moved forward to electronic presentation of procedures. For the Constellation Program, another large step forward is being taken - to make procedures more interactive with the vehicle and to assist the crew in controlling the vehicle more efficiently and with less error. The overall name for the project is the Constellation Procedure Applications Software System (CxPASS). This paper describes some of the history behind this effort, the key concepts and operational paradigms that the work is based upon, and the actual products being developed to implement procedures for Constellation

  4. 78 FR 27032 - National Maritime Week Tugboat Races, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ... Maritime Week Tugboat Races, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of... Maritime Week Tugboat Races in Elliott Bay, WA from 12 p.m. until 4:30 p.m. on May 11, 2013. This action is... for the annual National Maritime Week Tugboat Races, Seattle, WA listed in 33 CFR 100.1306 on May 11...

  5. 77 FR 65582 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-29

    .... Div., Back Office Customer Support, Primary Services & Inceed. 81,972 Pharmetrics, An IMS Health... Constellation Homebuilder Redmond, WA September 14, 2011. Systems, Fast Division, Constellation Software, Inc...

  6. Constellation Program: Lessons Learned. Volume 1; Executive Summary

    NASA Technical Reports Server (NTRS)

    Rhatigan, Jennifer L. (Editor)

    2011-01-01

    This document (Volume I) provides an executive summary of the lessons learned from the Constellation Program. A companion Volume II provides more detailed analyses for those seeking further insight and information. In this volume, Section 1.0 introduces the approach in preparing and organizing the content to enable rapid assimilation of the lessons. Section 2.0 describes the contextual framework in which the Constellation Program was formulated and functioned that is necessary to understand most of the lessons. Context of a former program may seem irrelevant in the heady days of new program formulation. However, readers should take some time to understand the context. Many of the lessons would be different in a different context, so the reader should reflect on the similarities and differences in his or her current circumstances. Section 3.0 summarizes key findings developed from the significant lessons learned at the program level that appear in Section 4.0. Readers can use the key findings in Section 3.0 to peruse for particular topics, and will find more supporting detail and analyses in Section 4.0 in a topical format. Appendix A contains a white paper describing the Constellation Program formulation that may be of use to readers wanting more context or background information. The reader will no doubt recognize some very similar themes from previous lessons learned, blue-ribbon committee reviews, National Academy reviews, and advisory panel reviews for this and other large-scale human spaceflight programs; including Apollo, Space Shuttle, Shuttle/Mir, and the ISS. This could represent an inability to learn lessons from previous generations; however, it is more likely that similar challenges persist in the Agency structure and approach to program formulation, budget advocacy, and management. Perhaps the greatest value of these Constellation lessons learned can be found in viewing them in context with these previous efforts to guide and advise the Agency and its

  7. Multiple Autonomous Discrete Event Controllers for Constellations

    NASA Technical Reports Server (NTRS)

    Esposito, Timothy C.

    2003-01-01

    The Multiple Autonomous Discrete Event Controllers for Constellations (MADECC) project is an effort within the National Aeronautics and Space Administration Goddard Space Flight Center's (NASA/GSFC) Information Systems Division to develop autonomous positioning and attitude control for constellation satellites. It will be accomplished using traditional control theory and advanced coordination algorithms developed by the Johns Hopkins University Applied Physics Laboratory (JHU/APL). This capability will be demonstrated in the discrete event control test-bed located at JHU/APL. This project will be modeled for the Leonardo constellation mission, but is intended to be adaptable to any constellation mission. To develop a common software architecture. the controllers will only model very high-level responses. For instance, after determining that a maneuver must be made. the MADECC system will output B (Delta)V (velocity change) value. Lower level systems must then decide which thrusters to fire and for how long to achieve that (Delta)V.

  8. Analysis For Monitoring the Earth Science Afternoon Constellation

    NASA Technical Reports Server (NTRS)

    Demarest, Peter; Richon, Karen V.; Wright, Frank

    2005-01-01

    The Earth Science Afternoon Constellation consists of Aqua, Aura, PARASOL, CALIPSO, Cloudsat, and the Orbiting Carbon Observatory (OCO). The coordination of flight dynamics activities between these missions is critical to the safety and success of the Afternoon Constellation. This coordination is based on two main concepts, the control box and the zone-of-exclusion. This paper describes how these two concepts are implemented in the Constellation Coordination System (CCS). The CCS is a collection of tools that enables the collection and distribution of flight dynamics products among the missions, allows cross-mission analyses to be performed through a web-based interface, performs automated analyses to monitor the overall constellation, and notifies the missions of changes in the status of the other missions.

  9. Autonomy for Constellation

    NASA Technical Reports Server (NTRS)

    Truszkowski, Walt; Szczur, Martha R. (Technical Monitor)

    2000-01-01

    The newer types of space systems, which are planned for the future, are placing challenging demands for newer autonomy concepts and techniques. Motivating these challenges are resource constraints. Even though onboard computing power will surely increase in the coming years, the resource constraints associated with space-based processes will continue to be a major factor that needs to be considered when dealing with, for example, agent-based spacecraft autonomy. To realize "economical intelligence", i.e., constrained computational intelligence that can reside within a process under severe resource constraints (time, power, space, etc.), is a major goal for such space systems as the Nanosat constellations. To begin to address the new challenges, we are developing approaches to constellation autonomy with constraints in mind. Within the Agent Concepts Testbed (ACT) at the Goddard Space Flight Center we are currently developing a Nanosat-related prototype for the first of the two-step program.

  10. NanoSat Constellation Mission Design

    NASA Technical Reports Server (NTRS)

    Concha, Marco; DeFazio, Robert

    1998-01-01

    The NanoSat constellation concept mission proposes simultaneous operation of multiple swarms of as many as 22 identical 10 kg spacecraft per swarm. The various orbits in a NanoSat swarm vary from 3x12 to 3x42 R(sub e) in geometry. In this report the unique flight dynamics issues of this constellation satellite mission design are addressed. Studies include orbit design, orbit determination, and error analysis. A preliminary survey determined the orbital parameters that would limit the maximum shadow condition while providing adequate ground station access for three ground stations.

  11. High prevalence of Cryptosporidium bovis and the deer-like genotype in calves compared to mature cows in beef cow-calf operations.

    PubMed

    Feltus, Dawn C; Giddings, Catherine W; Khaitsa, Margaret L; McEvoy, John M

    2008-02-14

    Recent studies have identified the novel, host adapted Cryptosporidium bovis and the deer-like genotype in dairy cattle from farms in the United States, China, India and Europe. This novel species and genotype appear to be more prevalent in older, post-weaned dairy cattle than previously thought. However, little information is available on their prevalence in beef cow-calf operations. In the present study, we determined the prevalence of Cryptosporidium species in 98 calves (6-8 months old) and 114 cows (>2 years old) in seven beef cow-calf herds in western North Dakota. DNA was extracted from fecal samples and Cryptosporidium spp. were identified by amplification of the 18S rRNA gene followed by sequencing or RFLP analysis. All seven herds tested positive for Cryptosporidium. Overall, 43/212 (20.3%) animals were positive. Only five of these positives were from cows. C. bovis, the deer-like genotype and C. andersoni were identified in 9.4, 6.6 and 1.4% of animals sampled, respectively. C. parvum was not identified in any of the positive samples. C. bovis, the deer-like genotype and C. andersoni were detected in 6/7, 5/7 and 2/7 herds, respectively. C. bovis and the deer-like genotype were primarily detected in calves, while C. andersoni was only detected in cows. Six isolates could not be typed. These results show a relatively high prevalence of C. bovis and the deer-like genotype in 6-8-month-old beef calves compared to cows older than 2 years in the seven herds studied.

  12. Using Problem-Based Learning: New Constellations for the 21st Century

    ERIC Educational Resources Information Center

    Savin-Baden, Maggi

    2014-01-01

    The author argues that there is still too much teaching to the test, and the consequence is growing "constellations" of problem-based learning (PBL), some of which are useful, and some of which are not. Today, what passes for PBL practice often seems more like guidelines than any kind of reasoned pedagogy. While at one level the range of…

  13. Life Support Technology Challenges for NASA's Constellation Program

    NASA Technical Reports Server (NTRS)

    Carrasquillo, Robyn; Bagdigian, Robert; Ewert, Michael

    2007-01-01

    The presentation is for the ECLSS session of the Constellation Technology Exchange Conference and is to describe what new technology challenges the Constellation mission presents for the ECLSS, in order to communicate these needs with industry.

  14. Beta Pic observations requested for BRITE-Constellation

    NASA Astrophysics Data System (ADS)

    Waagen, Elizabeth O.

    2017-01-01

    The AAVSO is part of the BRITE-Constellation Ground Based Observations Team (GBOT), supporting cutting-edge science from the BRITE-Constellation satellites and coordinating with BRITE-Constellation scientist Dr. Konstanze Zwintz (Universitaet Innsbruck) and her team. The delta Scuti star beta Pic (NSV 16683) (3.80-3.86V) is one of the BRITE stars being focused on during this season. Bet Pic is particularly interesting now because a transit of the star's planet's Hill sphere (the region around a planet in which it dominates the attraction of satellites) is predicted to occur during 2017-2018. Ongoing observations beginning now are valuable to establish a baseline prior to the transit. The AAVSO's webpage on the BRITE target stars was updated in November with information on bet Pic from Dr. Zwintz. AAVSO observers with appropriate equipment and located at a southern enough latitude are encouraged to observe bet Pic. Its brightness makes bet Pic well suited to PEP and DSLR photometry; CCD photometry is also possible. However, great care must be taken by all observers, especially those using CCD, to avoid saturation. As the amplitude of this star is very small, visual observations are very difficult, but they are welcome. Multicolor (BVR) photometry better than 0.01 magnitude and time-series observations with a cadence of a few minutes (less than 10 minutes) are requested beginning now and continuing at least through 2017 and likely through 2018. The precision and cadence required are essential in order for the data to be most useful for studying the transit. Spectroscopists wishing to participate should submit their spectra directly to Dr. Konstanze Zwintz (konstanze.zwintz@uibk.ac.at). Finder charts with sequence may be created using the AAVSO Variable Star Plotter (https://www.aavso.org/vsp). Observations should be submitted to the AAVSO International Database. See full Alert Notice for more details.

  15. Test and Verification Approach for the NASA Constellation Program

    NASA Technical Reports Server (NTRS)

    Strong, Edward

    2008-01-01

    This viewgraph presentation is a test and verification approach for the NASA Constellation Program. The contents include: 1) The Vision for Space Exploration: Foundations for Exploration; 2) Constellation Program Fleet of Vehicles; 3) Exploration Roadmap; 4) Constellation Vehicle Approximate Size Comparison; 5) Ares I Elements; 6) Orion Elements; 7) Ares V Elements; 8) Lunar Lander; 9) Map of Constellation content across NASA; 10) CxP T&V Implementation; 11) Challenges in CxP T&V Program; 12) T&V Strategic Emphasis and Key Tenets; 13) CxP T&V Mission & Vision; 14) Constellation Program Organization; 15) Test and Evaluation Organization; 16) CxP Requirements Flowdown; 17) CxP Model Based Systems Engineering Approach; 18) CxP Verification Planning Documents; 19) Environmental Testing; 20) Scope of CxP Verification; 21) CxP Verification - General Process Flow; 22) Avionics and Software Integrated Testing Approach; 23) A-3 Test Stand; 24) Space Power Facility; 25) MEIT and FEIT; 26) Flight Element Integrated Test (FEIT); 27) Multi-Element Integrated Testing (MEIT); 28) Flight Test Driving Principles; and 29) Constellation s Integrated Flight Test Strategy Low Earth Orbit Servicing Capability.

  16. Streamlining the Design Tradespace for Earth Imaging Constellations

    NASA Technical Reports Server (NTRS)

    Nag, Sreeja; Hughes, Steven P.; Le Moigne, Jacqueline J.

    2016-01-01

    Satellite constellations and Distributed Spacecraft Mission (DSM) architectures offer unique benefits to Earth observation scientists and unique challenges to cost estimators. The Cost and Risk (CR) module of the Tradespace Analysis Tool for Constellations (TAT-C) being developed by NASA Goddard seeks to address some of these challenges by providing a new approach to cost modeling, which aggregates existing Cost Estimating Relationships (CER) from respected sources, cost estimating best practices, and data from existing and proposed satellite designs. Cost estimation through this tool is approached from two perspectives: parametric cost estimating relationships and analogous cost estimation techniques. The dual approach utilized within the TAT-C CR module is intended to address prevailing concerns regarding early design stage cost estimates, and offer increased transparency and fidelity by offering two preliminary perspectives on mission cost. This work outlines the existing cost model, details assumptions built into the model, and explains what measures have been taken to address the particular challenges of constellation cost estimating. The risk estimation portion of the TAT-C CR module is still in development and will be presented in future work. The cost estimate produced by the CR module is not intended to be an exact mission valuation, but rather a comparative tool to assist in the exploration of the constellation design tradespace. Previous work has noted that estimating the cost of satellite constellations is difficult given that no comprehensive model for constellation cost estimation has yet been developed, and as such, quantitative assessment of multiple spacecraft missions has many remaining areas of uncertainty. By incorporating well-established CERs with preliminary approaches to approaching these uncertainties, the CR module offers more complete approach to constellation costing than has previously been available to mission architects or Earth

  17. Molecular characterization of rotavirus strains detected during a clinical trial of a human rotavirus vaccine in Blantyre, Malawi

    PubMed Central

    Nakagomi, Toyoko; Nakagomi, Osamu; Dove, Winifred; Doan, Yen Hai; Witte, Desiree; Ngwira, Bagrey; Todd, Stacy; Steele, A Duncan; Neuzil, Kathleen M; Cunliffe, Nigel A

    2014-01-01

    The human, G1P[8] rotavirus vaccine (Rotarix) significantly reduced severe rotavirus gastroenteritis episodes in a clinical trial in South Africa and Malawi, but vaccine efficacy was lower in Malawi (49.5%) than reported in South Africa (76.9%) and elsewhere. The aim of this study was to examine the molecular relationships of circulating wild-type rotaviruses detected during the clinical trial in Malawi to RIX4414 (the strain contained in Rotarix) and to common human rotavirus strains. Of 88 rotavirus-positive, diarrhoeal stool specimens, 43 rotaviruses exhibited identifiable RNA migration patterns when examined by polyacrylamide gel electrophoresis. The genes encoding VP7, VP4, VP6 and NSP4 of 5 representative strains possessing genotypes G12P[6], G1P[8], G9P[8], and G8P[4] were sequenced. While their VP7 (G) and VP4 (P) genotype designations were confirmed, the VP6 (I) and NSP4 (E) genotypes were either I1E1 or I2E2, indicating that they were of human rotavirus origin. RNA-RNA hybridization using 21 culture-adapted strains showed that Malawian rotaviruses had a genomic RNA constellation common to either the Wa-like or DS-1 like human rotaviruses. Overall, the Malawi strains appear similar in their genetic make-up to rotaviruses described in countries where vaccine efficacy is greater, suggesting that the lower efficacy in Malawi is unlikely to be explained by the diversity of circulating strains. PMID:22520123

  18. Science with Constellation-X

    NASA Technical Reports Server (NTRS)

    Hornschemeier, Ann (Editor); Garcia, Michael (Editor)

    2005-01-01

    NASA's upcoming Constellation-X mission, one of two flagship missions in the Beyond Einstein program, will have more than 100 times the collecting area of any previous spectroscopic mission operating in the 0.25-40 keV bandpass and will enable high-throughput, high spectral resolution studies of sources ranging from the most luminous accreting supermassive black holes in the Universe to the disks around young stars where planets form. This booklet, which was assembled during early 2005 using the contributions of a large team of Astrophysicists, outlines the important scientific questions for the decade following this one and describes the areas where Constellation-X is going to have a major impact. These areas include the exploration of the space-time geometry of black holes spanning nine orders of magnitude in mass and the nature of the dark energy and dark matter which govern the expansion and ultimate fate of the Universe. Constellation-X will also explore processes referred to as "cosmic feedback" whereby mechanical energy, radiation, and chemical elements from star formation and black holes are returned to interstellar and intergalactic medium, profoundly affecting the development of structure in the Universe, and will also probe all the important life cycles of matter, from stellar and planetary birth to stellar death via supernova to stellar endpoints in the form of accreting binaries and supernova remnants.

  19. Methodology and Method and Apparatus for Signaling With Capacity Optimized Constellations

    NASA Technical Reports Server (NTRS)

    Barsoum, Maged F. (Inventor); Jones, Christopher R. (Inventor)

    2014-01-01

    Communication systems are described that use geometrically shaped constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. In several embodiments, the geometrically shaped is optimized based upon a capacity measure such as parallel decoding capacity or joint capacity. In many embodiments, a capacity optimized geometrically shaped constellation can be used to replace a conventional constellation as part of a firmware upgrade to transmitters and receivers within a communication system. In a number of embodiments, the geometrically shaped constellation is optimized for an Additive White Gaussian Noise channel or a fading channel. In numerous embodiments, the communication uses adaptive rate encoding and the location of points within the geometrically shaped constellation changes as the code rate changes.

  20. Small Satellite Constellations for Geospace Sciences

    NASA Astrophysics Data System (ADS)

    Spence, H. E.

    2016-12-01

    The recent National Academy of Sciences Solar and Space Physics Decadal Survey (DS) identified community-consensus science priorities for the decade spanning 2013 - 2022. In this talk, we discuss the ways by which small satellite constellations are already and may soon accelerate progress toward achieving many of these science targets. The DS outlined four overarching science goals: (1) determine the origins of the Sun's activity and predict the variations in the space environment; (2) determine the dynamics and coupling of Earth's magnetosphere, ionosphere, and atmosphere and their response to solar and terrestrial inputs; (3) determine the interaction of the Sun with the solar system and the interstellar medium; and, (4) discover and characterize fundamental processes that occur both within the heliosphere and throughout the universe. These DS science goals provide the context for key science challenges in the three connected parts of the system that encompass all of solar and space physics, herein referred to as geospace: the Sun and heliosphere; the coupled solar wind-magnetosphere system; and, the coupled atmosphere-ionosphere-magnetosphere system. The DS further presented the role that small satellites play in resolving many of these science challenges, with a particular emphasis on the role that constellations of small satellites will play. While once considered by many as being "futuristic" or even "unrealizable", constellations of small satellites are already making important contributions to geospace science and with the promise for more to come. Using the DS as a guidepost, in this presentation, we outline representative small satellite constellation missions alread underway, some in development, and others notionally proposed over the next several years that employ small satellite constellations to tackle large science imperatives. Finally, we give examples of key small satellite technologies in development that will potentially enable great scientific

  1. Comparative analysis of the Rotarix™ vaccine strain and G1P[8] rotaviruses detected before and after vaccine introduction in Belgium.

    PubMed

    Zeller, Mark; Heylen, Elisabeth; Tamim, Sana; McAllen, John K; Kirkness, Ewen F; Akopov, Asmik; De Coster, Sarah; Van Ranst, Marc; Matthijnssens, Jelle

    2017-01-01

    G1P[8] rotaviruses are responsible for the majority of human rotavirus infections worldwide. The effect of universal mass vaccination with rotavirus vaccines on circulating G1P[8] rotaviruses is still poorly understood. Therefore we analyzed the complete genomes of the Rotarix™ vaccine strain, and 70 G1P[8] rotaviruses, detected between 1999 and 2010 in Belgium (36 before and 34 after vaccine introduction) to investigate the impact of rotavirus vaccine introduction on circulating G1P[8] strains. All rotaviruses possessed a complete Wa-like genotype constellation, but frequent intra-genogroup reassortments were observed as well as multiple different cluster constellations circulating in a single season. In addition, identical cluster constellations were found to circulate persistently over multiple seasons. The Rotarix™ vaccine strain possessed a unique cluster constellation that was not present in currently circulating G1P[8] strains. At the nucleotide level, the VP6, VP2 and NSP2 gene segments of Rotarix™ were relatively distantly related to any Belgian G1P[8] strain, but other gene segments of Rotarix™ were found in clusters also containing circulating Belgian strains. At the amino acid level, the genetic distance between Rotarix™ and circulating Belgian strains was considerably lower, except for NSP1. When we compared the Belgian G1P[8] strains collected before and after vaccine introduction a reduction in the proportion of strains that were found in the same cluster as the Rotarix™ vaccine strain was observed for most gene segments. The reduction in the proportion of strains belonging to the same cluster may be the result of the vaccine introduction, although natural fluctuations cannot be ruled out.

  2. Constellation Training Facility Support

    NASA Technical Reports Server (NTRS)

    Flores, Jose M.

    2008-01-01

    The National Aeronautics and Space Administration is developing the next set of vehicles that will take men back to the moon under the Constellation Program. The Constellation Training Facility (CxTF) is a project in development that will be used to train astronauts, instructors, and flight controllers on the operation of Constellation Program vehicles. It will also be used for procedure verification and validation of flight software and console tools. The CxTF will have simulations for the Crew Exploration Vehicle (CEV), Crew Module (CM), CEV Service Module (SM), Launch Abort System (LAS), Spacecraft Adapter (SA), Crew Launch Vehicle (CLV), Pressurized Cargo Variant CM, Pressurized Cargo Variant SM, Cargo Launch Vehicle, Earth Departure Stage (EDS), and the Lunar Surface Access Module (LSAM). The Facility will consist of part-task and full-task trainers, each with a specific set of mission training capabilities. Part task trainers will be used for focused training on a single vehicle system or set of related systems. Full task trainers will be used for training on complete vehicles and all of its subsystems. Support was provided in both software development and project planning areas of the CxTF project. Simulation software was developed for the hydraulic system of the Thrust Vector Control (TVC) of the ARES I launch vehicle. The TVC system is in charge of the actuation of the nozzle gimbals for navigation control of the upper stage of the ARES I rocket. Also, software was developed using C standards to send and receive data to and from hand controllers to be used in CxTF cockpit simulations. The hand controllers provided movement in all six rotational and translational axes. Under Project Planning & Control, support was provided to the development and maintenance of integrated schedules for both the Constellation Training Facility and Missions Operations Facilities Division. These schedules maintain communication between projects in different levels. The Cx

  3. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    NASA Administrator Michael Griffin addresses NASA employees and members of the media about the responsibilities of the NASA centers associated with the Constellation Program for robotic and human Moon and Mars exploration during a NASA Update on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit: (NASA/Bill Ingalls)

  4. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    Dean Acosta, NASA Deputy Assistant Administrator and Press Secretary, left, moderates a NASA Update with NASA Administrator Michael Griffin, Scott J. Horowitz, NASA Associate Administrator for Exploration Systems and Jeff Hanley, Constellation Program Manager, right, on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit: (NASA/Bill Ingalls)

  5. Infusing Stretch Goal Requirements into the Constellation Program

    NASA Technical Reports Server (NTRS)

    Lee, Young H.; Galpin, Roger A.; Ingoldsby, Kevin

    2008-01-01

    In 2004, the Vision for Space Exploration (VSE) was announced by the United States President's Administration in an effort to explore space and to extend a human presence across our solar system. Subsequently, the National Aeronautics and Space Administration (NASA) established the Exploration Systems Mission Directorate (ESMD) to develop a constellation of new capabilities, supporting technologies, and foundational research that allows for the sustained and affordable exploration of space. Then, ESMD specified the primary mission for the Constellation Program to carry out a series of human expeditions, ranging from Low Earth Orbit (LEO) to the surface of Moon, Mars, and beyond for the purposes of conducting human exploration of space. Thus, the Constellation Program was established at the Lyndon B. Johnson Space Center (JSC) to manage the development of the flight and ground infrastructure and systems that can enable continued and extended human access to space. Constellation Program's "Design Objectives" call for an early attention to the program's life cycle costs management through the Program's Need, Goals, and Objectives (NGO) document, which provides the vision, scope, and key areas of focus for the Program. One general policy of the Constellation Program, found in the Constellation Architecture Requirements Document (CARD), states: "A sustainable program hinges on how effectively total life cycle costs are managed. Developmental costs are a key consideration, but total life cycle costs related to the production, processing, and operation of the entire architecture must be accounted for in design decisions sufficiently to ensure future resources are available for ever more ambitious missions into the solar system....It is the intent of the Constellation Program to aggressively manage this aspect of the program using the design policies and simplicity." To respond to the Program's strong desire to manage the program life cycle costs, special efforts were

  6. Explaining and predicting individually experienced liking of berry fractions by the hTAS2R38 taste receptor genotype.

    PubMed

    Laaksonen, Oskar; Ahola, Johanna; Sandell, Mari

    2013-02-01

    The roles of taste and astringent properties, food choice motives and health concerns in liking of bilberry and crowberry samples were studied using a sensory panel prescreened for the hTAS2R38 taste receptor genotype. The subjects rated the intensity of sourness, bitterness and two astringent properties (soft, velvety and rough, puckering) of all berry samples. They also scored the liking of juice fractions and completed a food choice motive and health concern questionnaire. Regression models were used to combine different data sets and to predict liking of the extracts. Sourness contributed positively to the liking of berry fractions, and bitterness and rough astringency were negative factors. The hTAS2R38 genotype affected the liking of polyphenol-rich extracts, which were significantly bitter and astringent. Based on the genotype grouping of subjects, PAV homozygotes gave lower ratings to the attributes than AVI homozygotes. In contrast, PAV homozygotes were predicted to dislike the extracts notably more than AVI homozygotes. Health concern and food choice motives related to health and weight control had significant roles in individual liking of juice fractions. Our results indicate that mood was more important to the PAV homozygotes than to the AVI homozygotes. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. Methodology and method and appartus for signaling with capacity optimized constellations

    NASA Technical Reports Server (NTRS)

    Barsoum, Maged F. (Inventor); Jones, Christopher R. (Inventor)

    2012-01-01

    Communication systems are described that use geometrically shaped constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. In several embodiments, the geometrically shaped is optimized based upon a capacity measure such as parallel decoding capacity or joint capacity. In many embodiments, a capacity optimized geometrically shaped constellation can be used to replace a conventional constellation as part of a firmware upgrade to transmitters and receivers within a communication system. In a number of embodiments, the geometrically shaped constellation is optimized for an Additive White Gaussian Noise channel or a fading channel.

  8. Methodology and Method and Apparatus for Signaling with Capacity Optimized Constellations

    NASA Technical Reports Server (NTRS)

    Barsoum, Maged F. (Inventor); Jones, Christopher R. (Inventor)

    2017-01-01

    Communication systems are described that use geometrically shaped constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. In several embodiments, the geometrically shaped is optimized based upon a capacity measure such as parallel decoding capacity or joint capacity. In many embodiments, a capacity optimized geometrically shaped constellation can be used to replace a conventional constellation as part of a firmware upgrade to transmitters and receivers within a communication system. In a number of embodiments, the geometrically shaped constellation is optimized for an Additive White Gaussian Noise channel or a fading channel.

  9. Whole-genome characterization of a Peruvian alpaca rotavirus isolate expressing a novel VP4 genotype.

    PubMed

    Rojas, Miguel; Gonçalves, Jorge Luiz S; Dias, Helver G; Manchego, Alberto; Pezo, Danilo; Santos, Norma

    2016-11-30

    The SA44 isolate of Rotavirus A (RVA) was identified from a neonatal Peruvian alpaca presenting with diarrhea, and the full-length genome sequence of the isolate (designated RVA/Alpaca-tc/PER/SA44/2014/G3P[40]) was determined. Phylogenetic analyses showed that the isolate possessed the genotype constellation G3-P[40]-I8-R3-C3-M3-A9-N3-T3-E3-H6, which differs considerably from those of RVA strains isolated from other species of the order Artiodactyla. Overall, the genetic constellation of the SA44 strain was quite similar to those of RVA strains isolated from a bat in Asia (MSLH14 and MYAS33). Nonetheless, phylogenetic analyses of each genome segment identified a distinct combination of genes. Several sequences were closely related to corresponding gene sequences in RVA strains from other species, including human (VP1, VP2, NSP1, and NSP2), simian (VP3 and NSP5), bat (VP6 and NSP4), and equine (NSP3). The VP7 gene sequence was closely related to RVA strains from a Peruvian alpaca (K'ayra/3368-10; 99.0% nucleotide and 99.7% amino acid identity) and from humans (RCH272; 95% nucleotide and 99.0% amino acid identity). The nucleotide sequence of the VP4 gene was distantly related to other VP4 sequences and was designated as the reference strain for the new P[40] genotype. This unique genetic makeup suggests that the SA44 strain emerged from multiple reassortment events between bat-, equine-, and human-like RVA strains. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. Dependency of geodynamic parameters on the GNSS constellation

    NASA Astrophysics Data System (ADS)

    Scaramuzza, Stefano; Dach, Rolf; Beutler, Gerhard; Arnold, Daniel; Sušnik, Andreja; Jäggi, Adrian

    2018-01-01

    Significant differences in time series of geodynamic parameters determined with different Global Navigation Satellite Systems (GNSS) exist and are only partially explained. We study whether the different number of orbital planes within a particular GNSS contributes to the observed differences by analyzing time series of geocenter coordinates (GCCs) and pole coordinates estimated from several real and virtual GNSS constellations: GPS, GLONASS, a combined GPS/GLONASS constellation, and two virtual GPS sub-systems, which are obtained by splitting up the original GPS constellation into two groups of three orbital planes each. The computed constellation-specific GCCs and pole coordinates are analyzed for systematic differences, and their spectral behavior and formal errors are inspected. We show that the number of orbital planes barely influences the geocenter estimates. GLONASS' larger inclination and formal errors of the orbits seem to be the main reason for the initially observed differences. A smaller number of orbital planes may lead, however, to degradations in the estimates of the pole coordinates. A clear signal at three cycles per year is visible in the spectra of the differences between our estimates of the pole coordinates and the corresponding IERS 08 C04 values. Combinations of two 3-plane systems, even with similar ascending nodes, reduce this signal. The understanding of the relation between the satellite constellations and the resulting geodynamic parameters is important, because the GNSS currently under development, such as the European Galileo and the medium Earth orbit constellation of the Chinese BeiDou system, also consist of only three orbital planes.

  11. Design and implementation of satellite formations and constellations

    NASA Technical Reports Server (NTRS)

    Folta, David; Newman, Lauri Kraft; Quinn, David

    1998-01-01

    The direction to develop small low cost spacecraft has led many scientists to recognize the advantage of flying spacecraft in constellations and formations to achieve the correlated instrument measurements formerly possible only by flying many instruments on a single large platform. Yet, constellations and formation flying impose additional complications on orbit selection and orbit maintenance, especially when each spacecraft has its own orbit or science requirements. The purpose of this paper is to develop an operational control method for maintenance of these missions. Examples will be taken from the Earth Observing-1 (EO-1) spacecraft that is part of the New Millennium Program (NMP) and from proposed Earth System Science Program Office (ESSPO) constellations. Results can be used to determine the appropriateness of constellations and formation flying for a particular case as well as the operational impacts. Applications to the ESSPO and NMP are highly considered in analysis and applications. After constellation and formation analysis is completed, implementation of a maneuver maintenance strategy becomes the driver. Advances in technology and automation by GSFC's Guidance, Navigation, and Control Center allow more of the burden of the orbit selection and maneuver maintenance to be automated and ultimately placed onboard the spacecraft, mitigating most of the associated operational concerns. This paper presents the GSFC closed-loop control method to fly in either constellations or formations through the use of an autonomous closed loop three-axis navigation control and innovative orbit maintenance support. Simulation results using AutoCon(TM) and FreeFlyer(TM) with various fidelity levels of modeling and algorithms are presented.

  12. Design and Implementation of Satellite Formations and Constellations

    NASA Technical Reports Server (NTRS)

    Folta, David; Newman, Lauri Kraft; Quinn, David

    1998-01-01

    The direction to develop small low cost spacecraft has led many scientists to recognize the advantage of flying spacecraft in constellations and formations to achieve the correlated instrument measurements formerly possible only by flying many instruments on a single large platform. Yet, constellations and formation flying impose additional complications on orbit selection and orbit maintenance, especially when each spacecraft has its own orbit or science requirements. The purpose of this paper is to develop an operational control method for maintenance of these missions. Examples will be taken from the Earth Observing-1 (EO-1) spacecraft that is part of the New Millennium Program (NMP) and from proposed Earth System Science Program Office (ESSPO) constellations. Results can be used to determine the appropriateness of constellations and formation flying for a particular case as well as the operational impacts. Applications to the ESSPO and NMP are highly considered in analysis and applications. After constellation and formation analysis is completed, implementation of a maneuver maintenance strategy becomes the driver. Advances in technology and automation by GSFC's Guidance, Navigation, and Control Center allow more of the burden of the orbit selection and maneuver maintenance to be automated and ultimately placed onboard the spacecraft, mitigating most of the associated operational concerns. This paper presents the GSFC closed-loop control method to fly in either constellations or formations through the use of an autonomous closed loop three-axis navigation control and innovative orbit maintenance support. Simulation results using AutoCon(Trademark) and FreeFlyer(Trademark) with various fidelity levels of modeling and algorithms are presented.

  13. A SmallSat constellation mission architecture for a GRACE-type mission design

    NASA Astrophysics Data System (ADS)

    Deccia, C. M. A.; Nerem, R. S.; Yunck, T.

    2017-12-01

    The Gravity Recovery and Climate Experiment (GRACE) launched in 2002 and has been providing invaluable information of Earth's time-varying gravity field and GRACE-FO will continue this time series. For this work, we focus on architectures of future post-GRACE-FO like missions. Single pairs of satellites like GRACE and GRACE-FO are inherently limited in their spatio-temporal coverage. Full global coverage for a single pair can take up to 30 days for spatial resolutions of a few hundred kilometers, thus a single satellite pair is unable to observe sub-monthly signals in the Earth's time varying gravity field (e.g. hydrologic signals, etc.). Small satellite systems are becoming increasingly affordable and will soon allow a constellation of GRACE-type satellites to be deployed, with the capability to range between multiple satellites. Here, using simulation studies, we investigate the performance of such a constellation for different numbers of satellites (N) and different orbital configurations, in order to understand the improved performance that might be gained from such future mission architectures.

  14. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    Scott J. Horowitz, NASA Associate Administrator for Exploration Systems, announces to NASA employees and members of the media the responsibilities of the NASA centers associated with the Constellation Program for robotic and human Moon and Mars exploration on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit: (NASA/Bill Ingalls)

  15. Constellation Program Update

    NASA Image and Video Library

    2006-06-04

    Dean Acosta, NASA Deputy Assistant Administrator and Press Secretary, left, moderates a NASA Update with NASA Administrator Michael Griffin, second from left, Scott J. Horowitz, NASA Associate Administrator for Exploration Systems and Jeff Hanley, Constellation Program Manager, right, on Wednesday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit: (NASA/Bill Ingalls)

  16. Constellations of Next Generation Gravity Missions: Simulations regarding optimal orbits and mitigation of aliasing errors

    NASA Astrophysics Data System (ADS)

    Hauk, M.; Pail, R.; Gruber, T.; Purkhauser, A.

    2017-12-01

    The CHAMP and GRACE missions have demonstrated the tremendous potential for observing mass changes in the Earth system from space. In order to fulfil future user needs a monitoring of mass distribution and mass transport with higher spatial and temporal resolution is required. This can be achieved by a Bender-type Next Generation Gravity Mission (NGGM) consisting of a constellation of satellite pairs flying in (near-)polar and inclined orbits, respectively. For these satellite pairs the observation concept of the GRACE Follow-on mission with a laser-based low-low satellite-to-satellite tracking (ll-SST) system and more precise accelerometers and state-of-the-art star trackers is adopted. By choosing optimal orbit constellations for these satellite pairs high frequency mass variations will be observable and temporal aliasing errors from under-sampling will not be the limiting factor anymore. As part of the European Space Agency (ESA) study "ADDCON" (ADDitional CONstellation and Scientific Analysis Studies of the Next Generation Gravity Mission) a variety of mission design parameters for such constellations are investigated by full numerical simulations. These simulations aim at investigating the impact of several orbit design choices and at the mitigation of aliasing errors in the gravity field retrieval by co-parametrization for various constellations of Bender-type NGGMs. Choices for orbit design parameters such as altitude profiles during mission lifetime, length of retrieval period, value of sub-cycles and choice of prograde versus retrograde orbits are investigated as well. Results of these simulations are presented and optimal constellations for NGGM's are identified. Finally, a short outlook towards new geophysical applications like a near real time service for hydrology is given.

  17. A New Synthesis for the Origin of the Greek Constellations

    NASA Astrophysics Data System (ADS)

    Schaefer, B. E.

    2005-08-01

    The Greek constellations constitute one of the longest enduring intellectual properties of humanity. While various papers attribute the origin of the constellations to many diverse possibilities, main stream historians view the origin as largely being in Mesopotamia after around 1350 BC with transmission to the Greeks around 500 BC or so. The evidence for this synthesis is cuneiform and iconographic records that first mention constellations from roughly 1350-500 BC. My recent research on precessional dating has added much detail to this old synthesis. The earliest surviving written description of the Greek constellations is Aratus' Phaenomenon, which is a copy of Eudoxus' lost book of the same name. Hipparchus' Commentary also extensively quotes from Eudoxus. With 172 observations from Eudoxus, I derive a precessional date of 1130 ± 80 BC and a latitude of 36.0 ± 0.9 degrees north. Further, the positioning of the southern void amongst the Greek constellations yields a date of 690 BC (with an uncertainty of 2-4 centuries) and a latitude of 33 degrees (with an uncertainty of 1-3 degrees) for the six southernmost constellations. The earliest surviving description of the Mesopotamian constellations is the MUL.APIN tablet series, with the oldest dated example from the 8th century BC. My precessional calculation gives a date of 1100 BC and a latitude of 33 north. I also see that Eudoxus and MUL.APIN share a substantial number of observations. In all, some Assyrian observer(s) between 33-36 degrees north latitude around the time of 1300-1000 BC apparently invented many of the constellations adopted by the Greeks and made a database of observations later repeated by MUL.APIN, Eudoxus, Aratus, and Hipparchus. But this is not the whole story, as this only accounts for 19 Greek constellations which are identical in stars and representation with the Mesopotamian sky. An additional 12 Greek constellations have the same star groups as the Babylonians yet have completely

  18. Constellation labeling optimization for bit-interleaved coded APSK

    NASA Astrophysics Data System (ADS)

    Xiang, Xingyu; Mo, Zijian; Wang, Zhonghai; Pham, Khanh; Blasch, Erik; Chen, Genshe

    2016-05-01

    This paper investigates the constellation and mapping optimization for amplitude phase shift keying (APSK) modulation, which is deployed in Digital Video Broadcasting Satellite - Second Generation (DVB-S2) and Digital Video Broadcasting - Satellite services to Handhelds (DVB-SH) broadcasting standards due to its merits of power and spectral efficiency together with the robustness against nonlinear distortion. The mapping optimization is performed for 32-APSK according to combined cost functions related to Euclidean distance and mutual information. A Binary switching algorithm and its modified version are used to minimize the cost function and the estimated error between the original and received data. The optimized constellation mapping is tested by combining DVB-S2 standard Low-Density Parity-Check (LDPC) codes in both Bit-Interleaved Coded Modulation (BICM) and BICM with iterative decoding (BICM-ID) systems. The simulated results validate the proposed constellation labeling optimization scheme which yields better performance against conventional 32-APSK constellation defined in DVB-S2 standard.

  19. Molecular evidence of a badger-associated Ehrlichia sp., a Candidatus Neoehrlichia lotoris-like genotype and Anaplasma marginale in dogs.

    PubMed

    Hornok, Sándor; Horváth, Gábor; Takács, Nóra; Farkas, Róbert; Szőke, Krisztina; Kontschán, Jenő

    2018-05-22

    The family Anaplasmataceae contains pathogenic and endosymbiotic bacteria of veterinary-medical importance. In this study, 90 blood samples from rural dogs, five blood samples from road-killed European badgers and 34 ticks, i.e. 27 Ixodes (Pholeoixodes) canisuga, six I. (Ph.) hexagonus and one Haemaphysalis concinna collected from the badgers were molecularly analysed for members of Anaplasmataceae. Apart from the molecular evidence of Anaplasma phagocytophilum in one dog and Wolbachia sp. associated with Dirofilaria repens in five dogs, four species/genotypes not yet known to occur in canine hosts have also been found. These included A. marginale in two dogs, a badger-associated Ehrlichia sp. in one dog, a Candidatus Neoehrlichia lotoris-like genotype in six dogs and the DNA of arthropod-associated wolbachiae in three dogs. In two badgers the DNA from the Candidatus N. lotoris-like genotype was identified. Among ticks, four I. canisuga carried the DNA of the above badger-associated Ehrlichia sp., one I. canisuga contained the Candidatus N. lotoris-like genotype, and in H. concinna Wolbachia DNA was present. In conclusion, results shown here should be interpreted as the first molecular evidence for exposure of dogs to three members of Anaplasmataceae, i.e. A. marginale, a badger-associated Ehrlichia sp. and a Candidatus N. lotoris-like agent. The presence of DNA in the blood of relevant animals may also indicate susceptibility to these bacteria, but in support of this, further studies are needed. Copyright © 2018 Elsevier GmbH. All rights reserved.

  20. The Earth Science Afternoon Constellation Contingency Procedures

    NASA Technical Reports Server (NTRS)

    Case, Warren F.; Richon, Karen

    2005-01-01

    The Earth Science Afternoon Constellation comprises NASA missions Aqua, Aura, CloudSat and the Orbiting Carbon Observatory (OCO), the joint NASA/CNES mission CALIPSO and the CNES mission PARASOL. Both NASA and CNES offices are responsible for ensuring that contingency plans or other arrangements exist to cope with contingencies within their respective jurisdictions until the conclusion of all Afternoon Constellation operations. The Mission Operations Working Group, comprised of members from each of the missions, has developed the high-level procedures for maintaining the safety of this constellation. Each contingency situation requires detailed analyses before any decisions are made. This paper describes these procedures, and includes defining what constitutes a contingency situation, the pertinent parameters involved in the contingency analysis and guidelines for the actions required, based on the results of the contingency analyses.

  1. What the Heliophysics System Observatory is teaching us about future constellations

    NASA Astrophysics Data System (ADS)

    Angelopoulos, V.

    2017-12-01

    Owing to the benign space weather during the recent solar cycle numerous Heliophysics missions have outlived their original purpose and have exceeded expectations in terms of science return. The simultaneous availability of several multi-spacecraft fleets also offers conjunction opportunities that compounds their science yield. It allows the Heliophysics System, a vast region of Sun-Earth interactions, to be peered through the colletive eyes of a fortuitous grand Observatory. The success of this Heliophysics/Geospace System Observatory (H/GSO) has been partly due to fuel resources available on THEMIS, allowing it to reconfigure its orbit lines of apsides, apogees and mean anomalies to optimize conjunctions with the rest of the H/GSO. The other part of the success has been a mandatory open data policy, the accessibility of the data though common data formats, unified analysis tools (e.g. SPEDAS) and distributed data repositories. Future constellations are motivated by the recent science lessons learned: Tight connections between dayside and nightside processes, evidenced by fortuitous conjunctions of ground and space-based assets, suggest that regional activations drive classical global modes of circulation. Like regional tornadoes and hurricanes synthesize global atmospheric weather that cannot be studied with 5 weather stations alone, one per continent, so do dayside reconnection, and nightside injections require more than a handful of point measurements. Like atmospheric weather, space weather too requires networks of stations built to meet a minimum set of requirements to "play together" and build on each other over time. Like Argo's >3000 buoys have revolutionized research, modeling and prediction by global circulation models, "space buoys" can study space weather fronts and double-up as monitors and inputs to space weather models, increasing fidelity and advance warning. Reconfigurability can allow versatility as the scientific targets adjust to the knowledge

  2. Constellation Program Press Conference

    NASA Image and Video Library

    2006-06-04

    NASA Administrator Michael Griffin, speaks during a press conference outlining specific center responsibilities associated with the Constellation Program for robotic and human Moon and Mars exploration, Monday, June 5, 2006, at NASA Headquarters in Washington. Photo Credit (NASA/Bill Ingalls)

  3. Nanosatellite constellation deployment using on-board magnetic torquer interaction with space plasma

    NASA Astrophysics Data System (ADS)

    Park, Ji Hyun; Matsuzawa, Shinji; Inamori, Takaya; Jeung, In-Seuck

    2018-04-01

    One of the advantages that drive nanosatellite development is the potential of multi-point observation through constellation operation. However, constellation deployment of nanosatellites has been a challenge, as thruster operations for orbit maneuver were limited due to mass, volume, and power. Recently, a de-orbiting mechanism using magnetic torquer interaction with space plasma has been introduced, so-called plasma drag. As no additional hardware nor propellant is required, plasma drag has the potential in being used as constellation deployment method. In this research, a novel constellation deployment method using plasma drag is proposed. Orbit decay rate of the satellites in a constellation is controlled using plasma drag in order to achieve a desired phase angle and phase angle rate. A simplified 1D problem is formulated for an elementary analysis of the constellation deployment time. Numerical simulations are further performed for analytical analysis assessment and sensitivity analysis. Analytical analysis and numerical simulation results both agree that the constellation deployment time is proportional to the inverse square root of magnetic moment, the square root of desired phase angle and the square root of satellite mass. CubeSats ranging from 1 to 3 U (1-3 kg nanosatellites) are examined in order to investigate the feasibility of plasma drag constellation on nanosatellite systems. The feasibility analysis results show that plasma drag constellation is feasible on CubeSats, which open up the possibility of CubeSat constellation missions.

  4. A cross-sectional observational study of helmet use among motorcyclists in Wa, Ghana.

    PubMed

    Akaateba, Millicent Awialie; Amoh-Gyimah, Richard; Yakubu, Ibrahim

    2014-03-01

    Motorcyclists' injuries and fatalities are a major public health concern in many developing countries including Ghana. This study therefore aimed to investigate the prevalence of helmet use among motorcyclists in Wa, Ghana. The method used involved a cross-sectional roadside observation at 12 randomly selected sites within and outside the CBD of Wa. A total of 14,467 motorcyclists made up of 11,360 riders and 3107 pillion riders were observed during the study period. Most observed riders (86.5%) and pillion riders (61.7%) were males. The overall prevalence of helmet use among the observed motorcyclists was 36.9% (95% CI: 36.1-37.7). Helmet use for riders was 45.8% (95% CI: 44.8-46.7) whilst that for pillion riders was 3.7% (95 CI: 3.0-4.4). Based on logistic regression analysis, higher helmet wearing rates were found to be significantly associated with female gender, weekdays, morning periods and at locations within the CBD. Riders at locations outside the CBD were about 7 times less likely to wear a helmet than riders within the CBD (48.9% compared to 42.3%; χ(2)(1)=49.526; p<0.001). The study concluded that despite the existence of a national helmet legislation that mandates the use of helmets by both riders and pillion riders on all roads in Ghana, helmet use is generally low in Wa. This suggests that all stakeholders in road safety should jointly intensify education on helmet use and pursue rigorous enforcement on all road types especially at locations outside the CBD to improve helmet use in Wa. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. PNWSGD Data Collection: Ellensburg, WA

    DOE Data Explorer

    Kuchar, Olga Anna [Battelle Memorial Institute

    2015-06-26

    5-minute energy data from January 1, 2008 - December 31, 2014 for the City of Ellensburg, WA, U.S.A. This data was collected under the Pacific Northwest Smart Grid Demonstration Project under the American Recovery and Reinvestment Act (ARRA).

  6. Genotype I of Japanese Encephalitis Virus Virus-like Particles Elicit Sterilizing Immunity against Genotype I and III Viral Challenge in Swine.

    PubMed

    Fan, Yi-Chin; Chen, Jo-Mei; Lin, Jen-Wei; Chen, Yi-Ying; Wu, Guan-Hong; Su, Kuan-Hsuan; Chiou, Ming-Tang; Wu, Shang-Rung; Yin, Ji-Hang; Liao, Jiunn-Wang; Chang, Gwong-Jen J; Chiou, Shyan-Song

    2018-05-10

    Swine are a critical amplifying host involved in human Japanese encephalitis (JE) outbreaks. Cross-genotypic immunogenicity and sterile protection are important for the current genotype III (GIII) virus-derived vaccines in swine, especially now that emerging genotype I (GI) JE virus (JEV) has replaced GIII virus as the dominant strain. Herein, we aimed to develop a system to generate GI JEV virus-like particles (VLPs) and evaluate the immunogenicity and protection of the GI vaccine candidate in mice and specific pathogen-free swine. A CHO-heparan sulfate-deficient (CHO-HS(-)) cell clone, named 51-10 clone, stably expressing GI-JEV VLP was selected and continually secreted GI VLPs without signs of cell fusion. 51-10 VLPs formed a homogeneously empty-particle morphology and exhibited similar antigenic activity as GI virus. GI VLP-immunized mice showed balanced cross-neutralizing antibody titers against GI to GIV viruses (50% focus-reduction micro-neutralization assay titers 71 to 240) as well as potent protection against GI or GIII virus infection. GI VLP-immunized swine challenged with GI or GIII viruses showed no fever, viremia, or viral RNA in tonsils, lymph nodes, and brains as compared with phosphate buffered saline-immunized swine. We thus conclude GI VLPs can provide sterile protection against GI and GIII viruses in swine.

  7. Geomorphologic Modeling of a Macro-Tidal Embayment With Extensive Tidal Flats: Skagit Bay, WA

    DTIC Science & Technology

    2009-01-01

    Tidal Flats: Skagit Bay , WA Lyle Hibler Pacific Northwest National Laboratory 1529 West Sequim Bay Road Sequim , WA 98382 phone: (360) 681...3616 fax: (360) 681-3681 email: lyle.hibler@pnl.gov Adam Maxwell Pacific Northwest National Laboratory 1529 West Sequim Bay Road Sequim , WA... Sequim Bay Road, Sequim ,WA,98382 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR

  8. Geomorphologic Modeling of a Macro-tidal Embayment with Extensive Tidal Flats: Skagit Bay, WA

    DTIC Science & Technology

    2008-01-01

    Bay , WA Lyle Hibler Pacific Northwest National Laboratory 1529 West Sequim Bay Road Sequim , WA 98382 phone: (360) 681-3616 fax: (360)681-3681...email: lyle.hibler@pnl.gov Adam Maxwell Pacific Northwest National Laboratory 1529 West Sequim Bay Road Sequim , WA 98382 phone: (360) 681... Sequim Bay Road, Sequim ,WA,98382 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10.

  9. Origins of the ancient constellations: I. The Mesopotamian traditions

    NASA Astrophysics Data System (ADS)

    Rogers, J. H.

    1998-02-01

    In the sky-map of ancient Babylon, constellations had two different roles, and thus developed into two overlapping traditions. One set of constellations represented the gods and their symbols; the other set represented rustic activities and provided a farming calendar. Many constellations were shared by the two traditions, but in some regions of sky there were alternative divine and rustic figures. These figures developed in stages from ~3200 BC to ~500 BC. Of the divine set, the most important (although the last to be finalised) were the twelve zodiacal signs, plus several associated animals (the serpent, crow, eagle, and fish), which were all transmitted to the classical Greek sky-map that we still use today. Conversely, the rustic constellations of workers and tools and animals were not transmitted to the West. However, a few of them may have survived in Bedouin Arab sky-maps of the first millennium AD.

  10. The design and networking of dynamic satellite constellations for global mobile communication systems

    NASA Technical Reports Server (NTRS)

    Cullen, Cionaith J.; Benedicto, Xavier; Tafazolli, Rahim; Evans, Barry

    1993-01-01

    Various design factors for mobile satellite systems, whose aim is to provide worldwide voice and data communications to users with hand-held terminals, are examined. Two network segments are identified - the ground segment (GS) and the space segment (SS) - and are seen to be highly dependent on each other. The overall architecture must therefore be adapted to both of these segments, rather than each being optimized according to its own criteria. Terrestrial networks are grouped and called the terrestrial segment (TS). In the SS, of fundamental importance is the constellation altitude. The effect of the altitude on decisions such as constellation design choice and on network aspects like call handover statistics are fundamental. Orbit resonance is introduced and referred to throughout. It is specifically examined for its useful properties relating to GS/SS connectivities.

  11. The BRITE Constellation Nanosatellite Mission: Testing, Commissioning, and Operations

    NASA Astrophysics Data System (ADS)

    Pablo, H.; Whittaker, G. N.; Popowicz, A.; Mochnacki, S. M.; Kuschnig, R.; Grant, C. C.; Moffat, A. F. J.; Rucinski, S. M.; Matthews, J. M.; Schwarzenberg-Czerny, A.; Handler, G.; Weiss, W. W.; Baade, D.; Wade, G. A.; Zocłońska, E.; Ramiaramanantsoa, T.; Unterberger, M.; Zwintz, K.; Pigulski, A.; Rowe, J.; Koudelka, O.; Orleański, P.; Pamyatnykh, A.; Neiner, C.; Wawrzaszek, R.; Marciniszyn, G.; Romano, P.; Woźniak, G.; Zawistowski, T.; Zee, R. E.

    2016-12-01

    BRIght Target Explorer (BRITE) Constellation, the first nanosatellite mission applied to astrophysical research, is a collaboration among Austria, Canada and Poland. The fleet of satellites (6 launched; 5 functioning) performs precise optical photometry of the brightest stars in the night sky. A pioneering mission like BRITE—with optics and instruments restricted to small volume, mass and power in several nanosatellites, whose measurements must be coordinated in orbit—poses many unique challenges. We discuss the technical issues, including problems encountered during on-orbit commissioning (especially higher-than-expected sensitivity of the CCDs to particle radiation). We describe in detail how the BRITE team has mitigated these problems, and provide a complete overview of mission operations. This paper serves as a template for how to effectively plan, build and operate future low-cost niche-driven space astronomy missions. Based on data collected by the BRITE Constellation satellite mission, designed, built, launched, operated and supported by the Austrian Research Promotion Agency (FFG), the University of Vienna, the Technical University of Graz, the Canadian Space Agency (CSA), the University of Toronto Institute for Aerospace Studies (UTIAS), the Foundation for Polish Science & Technology (FNiTP MNiSW), and National Science Centre (NCN).

  12. Optimizing space constellations for mobile satellite systems

    NASA Astrophysics Data System (ADS)

    Roussel, T.; Taisant, J.-P.

    Designing a mobile satellite system entails many complex trade-offs between a great number of parameters including: capacity, complexity of the payload, constellation geometry, number of satellites, quality of coverage, etc. This paper aims at defining a methodology which tries to split the variables to give rapidly some first results. The major input considered is the traffic assumption which would be offered by the system. A first key step is the choice of the best Rider or Walker constellation geometries - with different numbers of satellites - to insure a good quality of coverage over a selected service area. Another aspect to be addressed is the possible altitude location of the constellation, since it is limited by many constraints. The altitude ranges that seem appropriate considering the spatial environment, the launch and orbit keeping policy and the feasibility of the antenna allowing sufficient frequency reuse are briefly analyzed. To support these first considerations, some 'reference constellations' with similar coverage quality are chosen. The in-orbit capacity needed to support the assumed traffic is computed versus altitude. Finally, the exact number of satellite is determined. It comes as an optimum between a small number of satellites offering a high (and costly) power margin in bad propagation situation and a great number of less powerful satellites granting the same quality of service.

  13. Optimizing space constellations for mobile satellite systems

    NASA Technical Reports Server (NTRS)

    Roussel, T.; Taisant, J.-P.

    1993-01-01

    Designing a mobile satellite system entails many complex trade-offs between a great number of parameters including: capacity, complexity of the payload, constellation geometry, number of satellites, quality of coverage, etc. This paper aims at defining a methodology which tries to split the variables to give rapidly some first results. The major input considered is the traffic assumption which would be offered by the system. A first key step is the choice of the best Rider or Walker constellation geometries - with different numbers of satellites - to insure a good quality of coverage over a selected service area. Another aspect to be addressed is the possible altitude location of the constellation, since it is limited by many constraints. The altitude ranges that seem appropriate considering the spatial environment, the launch and orbit keeping policy and the feasibility of the antenna allowing sufficient frequency reuse are briefly analyzed. To support these first considerations, some 'reference constellations' with similar coverage quality are chosen. The in-orbit capacity needed to support the assumed traffic is computed versus altitude. Finally, the exact number of satellite is determined. It comes as an optimum between a small number of satellites offering a high (and costly) power margin in bad propagation situation and a great number of less powerful satellites granting the same quality of service.

  14. Dark Energy, Dark Matter and Science with Constellation-X

    NASA Technical Reports Server (NTRS)

    Cardiff, Ann Hornschemeier

    2005-01-01

    Constellation-X, with more than 100 times the collecting area of any previous spectroscopic mission operating in the 0.25-40 keV bandpass, will enable highthroughput, high spectral resolution studies of sources ranging from the most luminous accreting supermassive black holes in the Universe to the disks around young stars where planets form. This talk will review the updated Constellation-X science case, released in booklet form during summer 2005. The science areas where Constellation-X will have major impact include the exploration of the space-time geometry of black holes spanning nine orders of magnitude in mass and the nature of the dark energy and dark matter which govern the expansion and ultimate fate of the Universe. Constellation-X will also explore processes referred to as "cosmic feedback" whereby mechanical energy, radiation, and chemical elements from star formation and black holes are returned to interstellar and intergalactic medium, profoundly affecting the development of structure in the Universe, and will also probe all the important life cycles of matter, from stellar and planetary birth to stellar death via supernova to stellar endpoints in the form of accreting binaries and supernova remnants. This talk will touch upon all these areas, with particular emphasis on Constellation-X's role in the study of Dark Energy.

  15. WaVPeak: picking NMR peaks through wavelet-based smoothing and volume-based filtering.

    PubMed

    Liu, Zhi; Abbas, Ahmed; Jing, Bing-Yi; Gao, Xin

    2012-04-01

    Nuclear magnetic resonance (NMR) has been widely used as a powerful tool to determine the 3D structures of proteins in vivo. However, the post-spectra processing stage of NMR structure determination usually involves a tremendous amount of time and expert knowledge, which includes peak picking, chemical shift assignment and structure calculation steps. Detecting accurate peaks from the NMR spectra is a prerequisite for all following steps, and thus remains a key problem in automatic NMR structure determination. We introduce WaVPeak, a fully automatic peak detection method. WaVPeak first smoothes the given NMR spectrum by wavelets. The peaks are then identified as the local maxima. The false positive peaks are filtered out efficiently by considering the volume of the peaks. WaVPeak has two major advantages over the state-of-the-art peak-picking methods. First, through wavelet-based smoothing, WaVPeak does not eliminate any data point in the spectra. Therefore, WaVPeak is able to detect weak peaks that are embedded in the noise level. NMR spectroscopists need the most help isolating these weak peaks. Second, WaVPeak estimates the volume of the peaks to filter the false positives. This is more reliable than intensity-based filters that are widely used in existing methods. We evaluate the performance of WaVPeak on the benchmark set proposed by PICKY (Alipanahi et al., 2009), one of the most accurate methods in the literature. The dataset comprises 32 2D and 3D spectra from eight different proteins. Experimental results demonstrate that WaVPeak achieves an average of 96%, 91%, 88%, 76% and 85% recall on (15)N-HSQC, HNCO, HNCA, HNCACB and CBCA(CO)NH, respectively. When the same number of peaks are considered, WaVPeak significantly outperforms PICKY. WaVPeak is an open source program. The source code and two test spectra of WaVPeak are available at http://faculty.kaust.edu.sa/sites/xingao/Pages/Publications.aspx. The online server is under construction. statliuzhi

  16. WaVPeak: picking NMR peaks through wavelet-based smoothing and volume-based filtering

    PubMed Central

    Liu, Zhi; Abbas, Ahmed; Jing, Bing-Yi; Gao, Xin

    2012-01-01

    Motivation: Nuclear magnetic resonance (NMR) has been widely used as a powerful tool to determine the 3D structures of proteins in vivo. However, the post-spectra processing stage of NMR structure determination usually involves a tremendous amount of time and expert knowledge, which includes peak picking, chemical shift assignment and structure calculation steps. Detecting accurate peaks from the NMR spectra is a prerequisite for all following steps, and thus remains a key problem in automatic NMR structure determination. Results: We introduce WaVPeak, a fully automatic peak detection method. WaVPeak first smoothes the given NMR spectrum by wavelets. The peaks are then identified as the local maxima. The false positive peaks are filtered out efficiently by considering the volume of the peaks. WaVPeak has two major advantages over the state-of-the-art peak-picking methods. First, through wavelet-based smoothing, WaVPeak does not eliminate any data point in the spectra. Therefore, WaVPeak is able to detect weak peaks that are embedded in the noise level. NMR spectroscopists need the most help isolating these weak peaks. Second, WaVPeak estimates the volume of the peaks to filter the false positives. This is more reliable than intensity-based filters that are widely used in existing methods. We evaluate the performance of WaVPeak on the benchmark set proposed by PICKY (Alipanahi et al., 2009), one of the most accurate methods in the literature. The dataset comprises 32 2D and 3D spectra from eight different proteins. Experimental results demonstrate that WaVPeak achieves an average of 96%, 91%, 88%, 76% and 85% recall on 15N-HSQC, HNCO, HNCA, HNCACB and CBCA(CO)NH, respectively. When the same number of peaks are considered, WaVPeak significantly outperforms PICKY. Availability: WaVPeak is an open source program. The source code and two test spectra of WaVPeak are available at http://faculty.kaust.edu.sa/sites/xingao/Pages/Publications.aspx. The online server is under

  17. 78 FR 57788 - Amendment of Class E Airspace; Everett, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ...-0434; Airspace Docket No. 13-ANM-1] Amendment of Class E Airspace; Everett, WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at Everett, WA, to... the FAA. No comments were received. Class E airspace designations are published in paragraph 6004, of...

  18. Trade-space Analysis for Constellations

    NASA Astrophysics Data System (ADS)

    Le Moigne, J.; Dabney, P.; de Weck, O. L.; Foreman, V.; Grogan, P.; Holland, M. P.; Hughes, S. P.; Nag, S.

    2016-12-01

    Traditionally, space missions have relied on relatively large and monolithic satellites, but in the past few years, under a changing technological and economic environment, including instrument and spacecraft miniaturization, scalable launchers, secondary launches as well as hosted payloads, there is growing interest in implementing future NASA missions as Distributed Spacecraft Missions (DSM). The objective of our project is to provide a framework that facilitates DSM Pre-Phase A investigations and optimizes DSM designs with respect to a-priori Science goals. In this first version of our Trade-space Analysis Tool for Constellations (TAT-C), we are investigating questions such as: "How many spacecraft should be included in the constellation? Which design has the best cost/risk value?" The main goals of TAT-C are to: Handle multiple spacecraft sharing a mission objective, from SmallSats up through flagships, Explore the variables trade space for pre-defined science, cost and risk goals, and pre-defined metrics Optimize cost and performance across multiple instruments and platforms vs. one at a time. This paper describes the overall architecture of TAT-C including: a User Interface (UI) interacting with multiple users - scientists, missions designers or program managers; an Executive Driver gathering requirements from UI, then formulating Trade-space Search Requests for the Trade-space Search Iterator first with inputs from the Knowledge Base, then, in collaboration with the Orbit & Coverage, Reduction & Metrics, and Cost& Risk modules, generating multiple potential architectures and their associated characteristics. TAT-C leverages the use of the Goddard Mission Analysis Tool (GMAT) to compute coverage and ancillary data, streamlining the computations by modeling orbits in a way that balances accuracy and performance. TAT-C current version includes uniform Walker constellations as well as Ad-Hoc constellations, and its cost model represents an aggregate model

  19. Far East Scarlet-Like Fever Caused by a Few Related Genotypes of Yersinia pseudotuberculosis, Russia

    PubMed Central

    Timchenko, Nelly F.; Adgamov, Ruslan R.; Popov, Alexander F.; Psareva, Ekaterina K.; Sobyanin, Konstantin A.; Gintsburg, Alexander L.

    2016-01-01

    We used multivirulence locus sequence typing to analyze 68 Yersinia pseudotuberculosis isolated in Russia during 1973–2014, including 41 isolates from patients with Far East scarlet-like fever. Four genotypes were found responsible, with 1 being especially prevalent. Evolutionary analysis suggests that epidemiologic advantages could cause this genotype’s dominance. PMID:26889961

  20. Molecular characterization of rotavirus strains detected during a clinical trial of a human rotavirus vaccine in Blantyre, Malawi.

    PubMed

    Nakagomi, Toyoko; Nakagomi, Osamu; Dove, Winifred; Doan, Yen Hai; Witte, Desiree; Ngwira, Bagrey; Todd, Stacy; Duncan Steele, A; Neuzil, Kathleen M; Cunliffe, Nigel A

    2012-04-27

    The human, G1P[8] rotavirus vaccine (Rotarix™) significantly reduced severe rotavirus gastroenteritis episodes in a clinical trial in South Africa and Malawi, but vaccine efficacy was lower in Malawi (49.5%) than reported in South Africa (76.9%) and elsewhere. The aim of this study was to examine the molecular relationships of circulating wild-type rotaviruses detected during the clinical trial in Malawi to RIX4414 (the strain contained in Rotarix™) and to common human rotavirus strains. Of 88 rotavirus-positive, diarrhoeal stool specimens, 43 rotaviruses exhibited identifiable RNA migration patterns when examined by polyacrylamide gel electrophoresis. The genes encoding VP7, VP4, VP6 and NSP4 of 5 representative strains possessing genotypes G12P[6], G1P[8], G9P[8], and G8P[4] were sequenced. While their VP7 (G) and VP4 (P) genotype designations were confirmed, the VP6 (I) and NSP4 (E) genotypes were either I1E1 or I2E2, indicating that they were of human rotavirus origin. RNA-RNA hybridization using 21 culture-adapted strains showed that Malawian rotaviruses had a genomic RNA constellation common to either the Wa-like or the DS-1 like human rotaviruses. Overall, the Malawi strains appear similar in their genetic make-up to rotaviruses described in countries where vaccine efficacy is greater, suggesting that the lower efficacy in Malawi is unlikely to be explained by the diversity of circulating strains. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. 76 FR 22033 - National Maritime Week Tugboat Races, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-20

    ... Maritime Week Tugboat Races, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of... Maritime Week Tugboat Races in Elliott Bay, WA from 12 p.m. through 4:30 p.m. on May 14, 2011. This action... will enforce the Special Local Regulation for the annual National Maritime Week Tugboat Races, Seattle...

  2. GLADIS: GLobal AIS & Data-X International Satellite Constellation

    DTIC Science & Technology

    2008-01-01

    1Approved for public release; distribution is unlimited GLADIS : GLobal AIS & Data-X International Satellite Constellation Space-Based System for...TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE GLADIS : GLobal AIS & Data-X International Satellite Constellation 5a. CONTRACT NUMBER 5b...Maritime & Technology Challenges • GLADIS Mission Objective • AIS & Data-X capabilities • GLADIS Architecture • International Strategy – MSSIS as Model

  3. Optimizing Spacecraft Placement for Liaison Constellations

    NASA Technical Reports Server (NTRS)

    Chow, C. Channing; Villac, Benjamin F.; Lo, Martin W.

    2011-01-01

    A navigation and communications network is proposed to support an anticipated need for infrastructure in the Earth-Moon system. Periodic orbits will host the constellations while a novel, autonomous navigation strategy will guide the spacecraft along their path strictly based on satellite-to-satellite telemetry. In particular, this paper investigates the second stage of a larger constellation optimization scheme for multi-spacecraft systems. That is, following an initial orbit down-selection process, this analysis provides insights into the ancillary problem of spacecraft placement. Two case studies are presented that consider configurations of up to four spacecraft for a halo orbit and a cycler trajectory.

  4. The Family Constellation Scale.

    ERIC Educational Resources Information Center

    Lemire, David

    The Family Constellation Scale (FC Scale) is an instrument that assesses perceived birth order in families. It can be used in counseling to help initiate conversations about various traits and assumptions that tend to characterize first-born, middle-born children, youngest-born, and only children. It provides both counselors and clients insights…

  5. Similar view to WA1832; Historic view just west of powerhouse ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Similar view to WA-18-32; Historic view just west of powerhouse during reconstruction of penstocks and replacement of original Francis Turbine with pelton wheels, in 1912; looking northwest. (photographer unknown, ca 1912.) - Nooksack Falls Hydroelectric Plant, Route 542, Glacier, Whatcom County, WA

  6. Science Discoveries Enabled by Hosting Optical Imagers on Commercial Satellite Constellations

    NASA Astrophysics Data System (ADS)

    Erlandson, R. E.; Kelly, M. A.; Hibbitts, C.; Kumar, C.; Dyrud, L. P.

    2012-12-01

    The advent of commercial space activities that utilize large space-based constellations provide a new and cost effective opportunity to acquire multi-point observations. Previously, a custom designed space-based constellation, while technically feasible, would require a substantial monetary investment. However, commercial industry has now been entertaining the concept of hosting payloads on their space-based constellations resulting in low-cost access to space. Examples, include the low Earth orbit Iridium Next constellation as well as communication satellites in geostationary. In some of these constellations data distribution can be provided in real time, a feature relevant to applications in the areas of space weather and disaster monitoring. From the perspective of new scientific discoveries enabled by low cost access to space, the cost and thus value proposition is dramatically changed. For example, a constellation of sixty-six satellites (Iridium Next), hosting a single band or multi-spectral imager can now provide observations of the aurora with a spatial resolution of a few hundred meters at all local times and in both hemispheres simultaneously. Remote sensing of clouds is another example where it is now possible to acquire global imagery at resolutions between 100-1000m. Finally, land use imagery is another example where one can use either imaging or spectrographic imagers to solve a multitude of problems. In this work, we will discuss measurement architectures and the multi-disciplinary scientific discoveries that are enable by large space based constellations.

  7. Does the Constellation Program Offer Opportunities to Achieve Space Science Goals in Space?

    NASA Technical Reports Server (NTRS)

    Thronson, Harley A.; Lester, Daniel F.; Dissel, Adam F.; Folta, David C.; Stevens, John; Budinoff, Jason G.

    2008-01-01

    Future space science missions developed to achieve the most ambitious goals are likely to be complex, large, publicly and professionally very important, and at the limit of affordability. Consequently, it may be valuable if such missions can be upgraded, repaired, and/or deployed in space, either with robots or with astronauts. In response to a Request for Information from the US National Research Council panel on Science Opportunities Enabled by NASA's Constellation System, we developed a concept for astronaut-based in-space servicing at the Earth-Moon L1,2 locations that may be implemented by using elements of NASA's Constellation architecture. This libration point jobsite could be of great value for major heliospheric and astronomy missions operating at Earth-Sun Lagrange points. We explored five alternative servicing options that plausibly would be available within about a decade. We highlight one that we believe is both the least costly and most efficiently uses Constellation hardware that appears to be available by mid-next decade: the Ares I launch vehicle, Orion/Crew Exploration Vehicle, Centaur vehicle, and an airlock/servicing node developed for lunar surface operations. Our concept may be considered similar to the Apollo 8 mission: a valuable exercise before descent by astronauts to the lunar surface.

  8. Learning the Constellations: From Junior High to Undergraduate Descriptive Astronomy Class

    NASA Astrophysics Data System (ADS)

    Stephens, Denise C.; Hintz, Eric G.; Hintz, Maureen; Lawler, Jeannette; Jones, Michael; Bench, Nathan

    2015-01-01

    As part of two separate studies we have examined the ability of students to learn and remember a group of constellations, bright stars, and deep sky objects. For a group of junior high students we tested their knowledge of only the constellations by giving them a 'constellation quiz' without any instruction. We then provided the students with a lab session, and retested. We also tested a large number of undergraduate students in our descriptive astronomy classes, but in this case there were the same 30 constellations, 17 bright stars, and 3 deep sky objects. The undergraduate students were tested in a number of ways: 1) pre-testing without instruction, 2) self-reporting of knowledge, 3) normal constellation quizzes as part of the class, and 4) retesting students from previous semesters. This provided us with a set of baseline measurements, allowed us to track the learning curve, and test retention of the material. We will present our early analysis of the data.

  9. Improved candidate generation and coverage analysis methods for design optimization of symmetric multi-satellite constellations

    NASA Astrophysics Data System (ADS)

    Matossian, Mark G.

    1997-01-01

    Much attention in recent years has focused on commercial telecommunications ventures involving constellations of spacecraft in low and medium Earth orbit. These projects often require investments on the order of billions of dollars (US$) for development and operations, but surprisingly little work has been published on constellation design optimization for coverage analysis, traffic simulation and launch sequencing for constellation build-up strategies. This paper addresses the two most critical aspects of constellation orbital design — efficient constellation candidate generation and coverage analysis. Inefficiencies and flaws in the current standard algorithm for constellation modeling are identified, and a corrected and improved algorithm is presented. In the 1970's, John Walker and G. V. Mozhaev developed innovative strategies for continuous global coverage using symmetric non-geosynchronous constellations. (These are sometimes referred to as rosette, or Walker constellations. An example is pictured above.) In 1980, the late Arthur Ballard extended and generalized the work of Walker into a detailed algorithm for the NAVSTAR/GPS program, which deployed a 24 satellite symmetric constellation. Ballard's important contribution was published in his "Rosette Constellations of Earth Satellites."

  10. The New Millenium Program ST-5 Mission: Nanosatellite Constellation Trailblazer

    NASA Technical Reports Server (NTRS)

    Slavin, James A.

    1999-01-01

    NASA's New Millenium Program has recently selected the Nanosatellite Constellation Trailblazer (NCT) as its fifth mission (ST-5). NCT will consist of 3 small, very capable and highly autonomous satellites which will be operated as a single "constellation" with minimal ground operations support. Each spacecraft will be approximately 40 cm in diameter by 20 cm in height and weigh only 20 kg. These small satellites will incorporate 8 new technologies essential to the further miniaturization of space science spacecraft which need space flight validation. In this talk we will describe in greater detail the NCT mission concept and goals, the exciting new technologies it will validate, and the role of miniaturized particles and fields sensors in this project. Finally, NCT's pathfinder function for such future NASA missions as Magnetotail Constellation and Inner Magnetosphere Constellation will be discussed.

  11. 77 FR 75597 - Proposed Establishment of Class E Airspace; Wilbur, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-21

    ...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This action proposes to establish Class E airspace at Wilbur Airport, Wilbur, WA. Controlled airspace is...) standard instrument approach procedures at Wilbur Airport, Wilbur, WA. The FAA is proposing this action to...

  12. 75 FR 29963 - Proposed Revocation of Class E Airspace; Eastsound, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-28

    ... action proposes to remove Class E surface airspace at Orcas Island Airport, Eastsound, WA. Controlled... operations at Orcas Island Airport. DATES: Comments must be received on or before July 12, 2010. ADDRESSES... at Orcas Island Airport, Eastsound, WA. The controlled airspace is unnecessary because existing...

  13. CubeSat constellation design for air traffic monitoring

    NASA Astrophysics Data System (ADS)

    Nag, Sreeja; Rios, Joseph L.; Gerhardt, David; Pham, Camvu

    2016-11-01

    Suitably equipped global and local air traffic can be tracked. The tracking information may then be used for control from ground-based stations by receiving the Automatic Dependent Surveillance-Broadcast (ADS-B) signal. In this paper, we describe a tool for designing a constellation of small satellites which demonstrates, through high-fidelity modeling based on simulated air traffic data, the value of space-based ADS-B monitoring. It thereby provides recommendations for cost-efficient deployment of a constellation of small satellites to increase safety and situational awareness in the currently poorly-served surveillance area of Alaska. Air traffic data were obtained from NASA's Future ATM Concepts Evaluation Tool, for the Alaskan airspace over one day. The results presented were driven by MATLAB and the satellites propagated and coverage calculated using AGI's Satellite Tool. While Ad-hoc and precession spread constellations have been quantitatively evaluated, Walker constellations show the best performance in simulation. Sixteen satellites in two perpendicular orbital planes are shown to provide more than 99% coverage over representative Alaskan airspace and the maximum time gap where any airplane in Alaska is not covered is six minutes, therefore meeting the standard set by the International Civil Aviation Organization to monitor every airplane at least once every fifteen minutes. In spite of the risk of signal collision when multiple packets arrive at the satellite receiver, the proposed constellation shows 99% cumulative probability of reception within four minutes when the airplanes are transmitting every minute, and at 100% reception probability if transmitting every second. Data downlink can be performed using any of the three ground stations of NASA Earth Network in Alaska.

  14. Optimal design of the satellite constellation arrangement reconfiguration process

    NASA Astrophysics Data System (ADS)

    Fakoor, Mahdi; Bakhtiari, Majid; Soleymani, Mahshid

    2016-08-01

    In this article, a novel approach is introduced for the satellite constellation reconfiguration based on Lambert's theorem. Some critical problems are raised in reconfiguration phase, such as overall fuel cost minimization, collision avoidance between the satellites on the final orbital pattern, and necessary maneuvers for the satellites in order to be deployed in the desired position on the target constellation. To implement the reconfiguration phase of the satellite constellation arrangement at minimal cost, the hybrid Invasive Weed Optimization/Particle Swarm Optimization (IWO/PSO) algorithm is used to design sub-optimal transfer orbits for the satellites existing in the constellation. Also, the dynamic model of the problem will be modeled in such a way that, optimal assignment of the satellites to the initial and target orbits and optimal orbital transfer are combined in one step. Finally, we claim that our presented idea i.e. coupled non-simultaneous flight of satellites from the initial orbital pattern will lead to minimal cost. The obtained results show that by employing the presented method, the cost of reconfiguration process is reduced obviously.

  15. CRISPR-like sequences in Helicobacter pylori and application in genotyping.

    PubMed

    Bangpanwimon, Khotchawan; Sottisuporn, Jaksin; Mittraparp-Arthorn, Pimonsri; Ueaphatthanaphanich, Warattaya; Rattanasupar, Attapon; Pourcel, Christine; Vuddhakul, Varaporn

    2017-01-01

    Many bacteria and archaea possess a defense system called clustered regularly interspaced short palindromic repeats (CRISPR) associated proteins (CRISPR-Cas system) against invaders such as phages or plasmids. This system has not been demonstrated in Helicobacter pylori . The numbers of spacer in CRISPR array differ among bacterial strains and can be used as a genetic marker for bacterial typing. A total of 36 H. pylori isolates were collected from patients in three hospitals located in the central (PBH) and southern (SKH) regions of Thailand. It is of interest that CRISPR-like sequences of this bacterium were detected in vlpC encoded for VacA-like protein C. Virulence genes were investigated and the most pathogenic genotype ( cagA vacA s1m1) was detected in 17 out of 29 (58.6%) isolates from PBH and 5 out of 7 (71.4%) from SKH. vapD gene was identified in each one isolate from PBH and SKH. CRISPR-like sequences and virulence genes of 20 isolates of H. pylori obtained in this study were analyzed and CRISPR-virulence typing was constructed and compared to profiles obtained by the random amplification of polymorphic DNA (RAPD) technique. The discriminatory power (DI) of CRISPR-virulence typing was not different from RAPD typing. CRISPR-virulence typing in H. pylori is easy and reliable for epidemiology and can be used for inter-laboratory interpretation.

  16. FAST TRACK COMMUNICATION: Affine constellations without mutually unbiased counterparts

    NASA Astrophysics Data System (ADS)

    Weigert, Stefan; Durt, Thomas

    2010-10-01

    It has been conjectured that a complete set of mutually unbiased bases in a space of dimension d exists if and only if there is an affine plane of order d. We introduce affine constellations and compare their existence properties with those of mutually unbiased constellations. The observed discrepancies make a deeper relation between the two existence problems unlikely.

  17. Deterministic Wave Predictions from the WaMoS II

    DTIC Science & Technology

    2014-10-23

    Monitoring System WaMoS II as input to a wave pre- diction system . The utility of wave prediction is primarily ves- sel motion prediction. Specific...successful prediction. The envisioned prediction system may provide graphical output in the form of a decision support system (Fig. 1). Predictions are...quality and accuracy of WaMoS as input to a deterministic wave prediction system . In the context of this paper, the Time Now Forecast H e a v e Hindcast

  18. Mega-constellations Issues

    NASA Astrophysics Data System (ADS)

    Bastida Virgili, Benjamin; Krag, Holger

    2016-07-01

    Space traffic has always been subject to considerable fluctuations. In the past, these fluctuations have been mainly driven by geopolitical and economic factors. During the last years there has been a considerable increase due to the use of cubesats by non-traditional space operators, and due to a significant change of mission scopes and mission orbits in Low Earth Orbit (LEO). In the near future, however, many indications point to a further increase in the space traffic in LEO. This increase is mainly driven by a cheaper access to space, also triggered by the miniaturisation of spacecraft systems. An acceleration of this trend is expressed by the announcement of large constellations in LEO with the purpose to provide broadband internet communication, allowing to minimise the required infrastructure on Earth. The number of artificial objects in orbit continues to increase and, with it, a key threat to space sustainability. In response, space agencies have identified a set of mitigation guidelines aimed at enabling space users to reduce the generation of space debris by, for example, limiting the orbital lifetime of their spacecraft and of launcher stages after the end of their mission to 25 years in LEO. However, several recent studies have shown that, today, current guidelines for the LEO protected zone are insufficiently applied by space systems of all sizes. Under these conditions, a step increase in the launch rate is a potential concern for the environment, in particular if the current End of Life (EOL) behaviour prevails in the future. Even in a perfect behaviour w.r.t. the 25 year lifetime rule, the new traffic might lead to unrecoverable environment trends. Furthermore, the requirement for reliability of the disposal function is of 90%, however, weighted with the reliability of the entire system. A failure rate of 10%, in general, was found to be acceptable under current space traffic conditions. This might not be sustainable when the LEO launch rates

  19. 33 CFR 100.1306 - National Maritime Week Tugboat Races, Seattle, WA.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false National Maritime Week Tugboat Races, Seattle, WA. 100.1306 Section 100.1306 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Maritime Week Tugboat Races, Seattle, WA. (a) Regulated Area. A regulated area is established on that...

  20. 77 FR 26699 - Safety Zone; Coast Guard Exercise, Hood Canal, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... would be impracticable to delay this important exercise to allow for a delayed effective date...-AA00 Safety Zone; Coast Guard Exercise, Hood Canal, WA AGENCY: Coast Guard, DHS. ACTION: Temporary... a Coast Guard Ready for Operations exercise in Hood Canal, WA that will take place between May 08...

  1. 33 CFR 100.1306 - National Maritime Week Tugboat Races, Seattle, WA.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Races, Seattle, WA. 100.1306 Section 100.1306 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Maritime Week Tugboat Races, Seattle, WA. (a) Regulated Area. A regulated area is established on that... approximately 650 yards into Elliott Bay. Temporary floating markers will be placed by the race sponsors to...

  2. 33 CFR 100.1306 - National Maritime Week Tugboat Races, Seattle, WA.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Races, Seattle, WA. 100.1306 Section 100.1306 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Maritime Week Tugboat Races, Seattle, WA. (a) Regulated Area. A regulated area is established on that... approximately 650 yards into Elliott Bay. Temporary floating markers will be placed by the race sponsors to...

  3. 33 CFR 100.1306 - National Maritime Week Tugboat Races, Seattle, WA.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Races, Seattle, WA. 100.1306 Section 100.1306 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Maritime Week Tugboat Races, Seattle, WA. (a) Regulated Area. A regulated area is established on that... approximately 650 yards into Elliott Bay. Temporary floating markers will be placed by the race sponsors to...

  4. 33 CFR 100.1306 - National Maritime Week Tugboat Races, Seattle, WA.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Races, Seattle, WA. 100.1306 Section 100.1306 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Maritime Week Tugboat Races, Seattle, WA. (a) Regulated Area. A regulated area is established on that... approximately 650 yards into Elliott Bay. Temporary floating markers will be placed by the race sponsors to...

  5. Correlates and Barriers Associated with Motorcycle Helmet Use in Wa, Ghana.

    PubMed

    Akaateba, Millicent Awialie; Yakubu, Ibrahim; Akanbang, Bernard Afiik Akanpabadai

    2015-01-01

    This study was conducted to investigate the correlates and barriers to helmet use among motorcycle riders in Wa, a motorcycle-predominant town in Ghana. An additional objective was to determine the association between helmet use and riders' knowledge, attitudes, and beliefs toward helmets. Cross-sectional surveys including both observation of helmet use and interviews were conducted among motorcycle riders at 6 randomly selected fuel stations and 4 motorcycle service centers within and outside the Central Business District of Wa. Questions covered riders' sociodemographic and riding characteristics, helmet use, reasons for use or nonuse of helmets, and knowledge, attitudes, and beliefs about helmets. Analyses were based on frequencies and testing of strength of association using adjusted odds ratios (with 95% confidence intervals) in binary logistic regression. The prevalence of helmet use among the 271 sampled riders was 46% (95% confidence interval [CI], 40.2-52.0). Gender, age, marital status, and occupation were significant sociodemographic correlates of helmet use in Wa. Compared to currently married riders, unmarried riders were 5 times less likely to use a helmet. No significant association existed between riders' educational attainment and helmet use. Helmet use was also positively correlated with helmet ownership and license holding. The leading reasons stated for helmet nonuse among nonusers were not traveling a long distance and helmets block vision and hearing. Protection from injury, legal requirement, and coping with the police for fear of being accosted for helmet nonuse were identified as common reasons for helmet use. Positive attitudes and beliefs were also significantly correlated with helmet use. Despite the existence of a legislation mandating the use of helmets on all roads as well as the high level of awareness among riders on this legislation and the benefits of helmets, the incidence of helmet use among motorists continue to be low in Wa

  6. 75 FR 53572 - Safety Zone; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ...-AA00 Safety Zone; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA AGENCY: Coast Guard, DHS. ACTION... channel in Budd Inlet, WA during Olympia Harbor Days tug boat races. This safety zone is necessary to... waters of the Budd Inlet, WA during Olympia Harbor Days tug boat races. DATES: This rule is effective...

  7. Human Systems Integration in Practice: Constellation Lessons Learned

    NASA Technical Reports Server (NTRS)

    Zumbado, Jennifer Rochlis

    2012-01-01

    NASA's Constellation program provided a unique testbed for Human Systems Integration (HSI) as a fundamental element of the Systems Engineering process. Constellation was the first major program to have HSI mandated by NASA's Human Rating document. Proper HSI is critical to the success of any project that relies on humans to function as operators, maintainers, or controllers of a system. HSI improves mission, system and human performance, significantly reduces lifecycle costs, lowers risk and minimizes re-design. Successful HSI begins with sufficient project schedule dedicated to the generation of human systems requirements, but is by no means solely a requirements management process. A top-down systems engineering process that recognizes throughout the organization, human factors as a technical discipline equal to traditional engineering disciplines with authority for the overall system. This partners with a bottoms-up mechanism for human-centered design and technical issue resolution. The Constellation Human Systems Integration Group (HSIG) was a part of the Systems Engineering and Integration (SE&I) organization within the program office, and existed alongside similar groups such as Flight Performance, Environments & Constraints, and Integrated Loads, Structures and Mechanisms. While the HSIG successfully managed, via influence leadership, a down-and-in Community of Practice to facilitate technical integration and issue resolution, it lacked parallel top-down authority to drive integrated design. This presentation will discuss how HSI was applied to Constellation, the lessons learned and best practices it revealed, and recommendations to future NASA program and project managers. This presentation will discuss how Human Systems Integration (HSI) was applied to NASA's Constellation program, the lessons learned and best practices it revealed, and recommendations to future NASA program and project managers on how to accomplish this critical function.

  8. Constellation Program Life-cycle Cost Analysis Model (LCAM)

    NASA Technical Reports Server (NTRS)

    Prince, Andy; Rose, Heidi; Wood, James

    2008-01-01

    The Constellation Program (CxP) is NASA's effort to replace the Space Shuttle, return humans to the moon, and prepare for a human mission to Mars. The major elements of the Constellation Lunar sortie design reference mission architecture are shown. Unlike the Apollo Program of the 1960's, affordability is a major concern of United States policy makers and NASA management. To measure Constellation affordability, a total ownership cost life-cycle parametric cost estimating capability is required. This capability is being developed by the Constellation Systems Engineering and Integration (SE&I) Directorate, and is called the Lifecycle Cost Analysis Model (LCAM). The requirements for LCAM are based on the need to have a parametric estimating capability in order to do top-level program analysis, evaluate design alternatives, and explore options for future systems. By estimating the total cost of ownership within the context of the planned Constellation budget, LCAM can provide Program and NASA management with the cost data necessary to identify the most affordable alternatives. LCAM is also a key component of the Integrated Program Model (IPM), an SE&I developed capability that combines parametric sizing tools with cost, schedule, and risk models to perform program analysis. LCAM is used in the generation of cost estimates for system level trades and analyses. It draws upon the legacy of previous architecture level cost models, such as the Exploration Systems Mission Directorate (ESMD) Architecture Cost Model (ARCOM) developed for Simulation Based Acquisition (SBA), and ATLAS. LCAM is used to support requirements and design trade studies by calculating changes in cost relative to a baseline option cost. Estimated costs are generally low fidelity to accommodate available input data and available cost estimating relationships (CERs). LCAM is capable of interfacing with the Integrated Program Model to provide the cost estimating capability for that suite of tools.

  9. Simulating 3D Spacecraft Constellations for Low Frequency Radio Imaging

    NASA Astrophysics Data System (ADS)

    Hegedus, A. M.; Amiri, N.; Lazio, J.; Belov, K.; Kasper, J. C.

    2016-12-01

    Constellations of small spacecraft could be used to realize a low-frequency phased array for either heliophysics or astrophysics observations. However, there are issues that arise with an orbiting array that do not occur on the ground, thus rendering much of the existing radio astronomy software inadequate for data analysis and simulation. In this work we address these issues and consider the performance of two constellation concepts. The first is a 32-spacecraft constellation for astrophysical observations, and the second is a 5-element concept for pointing to the location of radio emission from coronal mass ejections (CMEs). For the first, we fill the software gap by extending the APSYNSIM software to simulate the aperture synthesis for a radio interferometer in orbit. This involves using the dynamic baselines from the relative motion of the individual spacecraft as well as the capability to add galactic noise. The ability to simulate phase errors corresponding to positional uncertainty of the antennas was also added. The upgraded software was then used to model the imaging of a 32 spacecraft constellation that would orbit the moon to image radio galaxies like Cygnus A at .3-30 MHz. Animated images showing the improvement of the dirty image as the orbits progressed were made. RMSE plots that show how well the dirty image matches the input image as a function of integration time were made. For the second concept we performed radio interferometric simulations of the Sun Radio Interferometer Space Experiment (SunRISE) using the Common Astronomy Software Applications (CASA) package. SunRISE is a five spacecraft phased array that would orbit Earth to localize the low frequency radio emission from CMEs. This involved simulating the array in CASA, creating truth images for the CMEs over the entire frequency band of SunRISE, and observing them with the simulated array to see how well it could localize the true position of the CME. The results of our analysis show that we

  10. An Investigation into Establishing a Formation of Small Satellites in a Lunar Flower Constellation

    NASA Astrophysics Data System (ADS)

    McManus, Lauren

    Lunar science missions such as LADEE and GRAIL achieved unprecedented measurements of the Lunar exosphere and gravity field. These missions were performed with one (LADEE) or two (GRAIL) traditional satellites. The global coverage achieved by these missions could have been greatly enhanced with the use of a constellation of satellites. A constellation of communication satellites at the Moon would also be necessary if a Lunar human base were to be established. Constellations with many satellites are expensive with traditional technology, but have become feasible through the technological advancements and affordability of cubesats. Cubesat constellations allow for full surface coverage in science or communication missions at a reasonable mission cost. Repeat ground track orbits offer interesting options for science or communication constellations, since they provide repeat coverage of the surface at a fixed time between sequential visits. Flower constellations are a family of constellations being studied primarily by Daniele Mortari at Texas A&M; University that make use of repeat ground tracks. Orbital parameters are selected such that the nodal period of the orbit matches the nodal period of the primary body by a factor dependent on the number of days and the number of revolutions to repeat the ground track. All orbits in a flower constellation have identical orbital elements, with the exception of the right ascension of the ascending node (RAAN) and the initial mean anomaly, which are determined based on the desired phasing scheme desired. Flower constellations have thus far primarily been studied at Earth. A flower constellation at the Moon could be quite useful for science or communication purposes. In this scenario, the flower constellation satellites would be small satellites, which introduces many unique challenges. The cubesats would have limited propulsion capability and would need to be deployed from a mothercraft. Orbital maintenance would then be

  11. Dynamics of an unusual cone-building trachyte eruption at Pu`u Wa`awa`a, Hualālai volcano, Hawai`i

    NASA Astrophysics Data System (ADS)

    Shea, Thomas; Leonhardi, Tanis; Giachetti, Thomas; Lindoo, Amanda; Larsen, Jessica; Sinton, John; Parsons, Elliott

    2017-04-01

    The Pu`u Wa`awa`a pyroclastic cone and Pu`u Anahulu lava flow are two prominent monogenetic eruptive features assumed to result from a single eruption during the trachyte-dominated early post-shield stage of Hualālai volcano (Hawaíi). Púu Wa`awa`a is composed of complex repetitions of crudely cross-stratified units rich in dark dense clasts, which reversely grade into coarser pumice-rich units. Pyroclasts from the cone are extremely diverse texturally, ranging from glassy obsidian to vesicular scoria or pumice, in addition to fully crystalline end-members. The >100-m thick Pu`u Anahulu flow is, in contrast, entirely holocrystalline. Using field observations coupled with whole rock analyses, this study aimed to test whether the Pu`u Wa`awa`a tephra and Pu`u Anahulu lava flows originated from the same eruption, as had been previously assumed. Crystal and vesicle textures are characterized along with the volatile contents of interstitial glasses to determine the origin of textural variability within Pu`u Wáawáa trachytes (e.g., magma mixing vs. degassing origin). We find that (1) the two eruptions likely originated from distinct vents and magma reservoirs, despite their proximity and similar age, (2) the textural diversity of pyroclasts forming Pu`u Wa`awa`a can be fully explained by variable magma degassing and outgassing within the conduit, (3) the Pu`u Wa`awa`a cone was constructed during explosions transitional in style between violent Strombolian and Vulcanian, involving the formation of a large cone and with repeated disruption of conduit plugs, but without production of large pyroclastic density currents (PDCs), and (4) the contrasting eruption styles of Hawaiian trachytes (flow-, cone-, and PDC-forming) are probably related to differences in the outgassing capacity of the magmas prior to reaching the surface and not in intrinsic compositional or temperature properties. These results further highlight that trachytes are "kinetically faster" magmas compared

  12. Methodology and method and apparatus for signaling with capacity optimized constellations

    NASA Technical Reports Server (NTRS)

    Barsoum, Maged F. (Inventor); Jones, Christopher R. (Inventor)

    2011-01-01

    Communication systems having transmitter, includes a coder configured to receive user bits and output encoded bits at an expanded output encoded bit rate, a mapper configured to map encoded bits to symbols in a symbol constellation, a modulator configured to generate a signal for transmission via the communication channel using symbols generated by the mapper. In addition, the receiver includes a demodulator configured to demodulate the received signal via the communication channel, a demapper configured to estimate likelihoods from the demodulated signal, a decoder that is configured to estimate decoded bits from the likelihoods generated by the demapper. Furthermore, the symbol constellation is a capacity optimized geometrically spaced symbol constellation that provides a given capacity at a reduced signal-to-noise ratio compared to a signal constellation that maximizes d.sub.min.

  13. Constellation Program Human-System Integration Requirements. Revision E, Nov. 19, 2010

    NASA Technical Reports Server (NTRS)

    Dory, Jonathan

    2010-01-01

    The Human-Systems Integration Requirements (HSIR) in this document drive the design of space vehicles, their systems, and equipment with which humans interface in the Constellation Program (CxP). These requirements ensure that the design of Constellation (Cx) systems is centered on the needs, capabilities, and limitations of the human. The HSIR provides requirements to ensure proper integration of human-to-system interfaces. These requirements apply to all mission phases, including pre-launch, ascent, Earth orbit, trans-lunar flight, lunar orbit, lunar landing, lunar ascent, Earth return, Earth entry, Earth landing, post-landing, and recovery. The Constellation Program must meet NASA's Agency-level human rating requirements, which are intended to ensure crew survival without permanent disability. The HSIR provides a key mechanism for achieving human rating of Constellation systems.

  14. Rare ADH Variant Constellations are Specific for Alcohol Dependence

    PubMed Central

    Zuo, Lingjun; Zhang, Heping; Malison, Robert T.; Li, Chiang-Shan R.; Zhang, Xiang-Yang; Wang, Fei; Lu, Lingeng; Lu, Lin; Wang, Xiaoping; Krystal, John H.; Zhang, Fengyu; Deng, Hong-Wen; Luo, Xingguang

    2013-01-01

    Aims: Some of the well-known functional alcohol dehydrogenase (ADH) gene variants (e.g. ADH1B*2, ADH1B*3 and ADH1C*2) that significantly affect the risk of alcohol dependence are rare variants in most populations. In the present study, we comprehensively examined the associations between rare ADH variants [minor allele frequency (MAF) <0.05] and alcohol dependence, with several other neuropsychiatric and neurological disorders as reference. Methods: A total of 49,358 subjects in 22 independent cohorts with 11 different neuropsychiatric and neurological disorders were analyzed, including 3 cohorts with alcohol dependence. The entire ADH gene cluster (ADH7–ADH1C–ADH1B–ADH1A–ADH6–ADH4–ADH5 at Chr4) was imputed in all samples using the same reference panels that included whole-genome sequencing data. We stringently cleaned the phenotype and genotype data to obtain a total of 870 single nucleotide polymorphisms with 0< MAF <0.05 for association analysis. Results: We found that a rare variant constellation across the entire ADH gene cluster was significantly associated with alcohol dependence in European-Americans (Fp1: simulated global P = 0.045), European-Australians (Fp5: global P = 0.027; collapsing: P = 0.038) and African-Americans (Fp5: global P = 0.050; collapsing: P = 0.038), but not with any other neuropsychiatric disease. Association signals in this region came principally from ADH6, ADH7, ADH1B and ADH1C. In particular, a rare ADH6 variant constellation showed a replicable association with alcohol dependence across these three independent cohorts. No individual rare variants were statistically significantly associated with any disease examined after group- and region-wide correction for multiple comparisons. Conclusion: We conclude that rare ADH variants are specific for alcohol dependence. The ADH gene cluster may harbor a causal variant(s) for alcohol dependence. PMID:23019235

  15. 76 FR 59898 - Special Local Regulation, Hydroplane Races, Lake Sammamish, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... Local Regulation, Hydroplane Races, Lake Sammamish, WA AGENCY: Coast Guard, DHS. ACTION: Notice of... hydroplane event in Lake Sammamish, WA from 11 a.m. until 4:30 p.m. from September 30, 2011 through October 2... within the Captain of the Port Puget Sound Area of Responsibility 33 CFR 100.1308. The Lake Sammamish...

  16. Changing prevalent T serotypes and emm genotypes of Streptococcus pyogenes isolates from streptococcal toxic shock-like syndrome (TSLS) patients in Japan.

    PubMed

    Ikebe, T; Murai, N; Endo, M; Okuno, R; Murayama, S; Saitoh, K; Yamai, S; Suzuki, R; Isobe, J; Tanaka, D; Katsukawa, C; Tamaru, A; Katayama, A; Fujinaga, Y; Hoashi, K; Ishikawa, J; Watanabe, H

    2003-06-01

    We surveyed T serotypes and emm genotypes of Streptococcus pyogenes isolates from streptococcal toxic shock-like syndrome (TSLS) patients. T1 (emm1) remained dominant through 1992 to 2000, but the dominant T3 (emm3.1) strains from 1992 to 1995 disappeared during 1996-2000. Strains of several emm genotypes emerged during 1996-2000, indicating alterations in the prevalent strains causing TSLS.

  17. Constellation X-Ray Mission and Support

    NASA Technical Reports Server (NTRS)

    Tananbaum, H.; Grady, Jean (Technical Monitor)

    2002-01-01

    This report is a supplement to the Third Annual Report summarizing work performed by the Smithsonian Astrophysical Observatory (SAO) for NASA Goddard Space Flight Center (GSFC) under Cooperative Agreement NCC5-3681. The Agreement is entitled 'Constellation X-ray Mission Study and Support.' This supplementary report covers the period from October 1, 2001 through January 10, 2002. The report has been prepared and submitted to ensure that the Constellation-X Project Office at GSFC has current performance information needed to evaluate a proposed modified budget for FY02. That proposed budget is being submitted separately. SAO continues to perform work under the overall direction of Dr. Harvey Tananbaum, the SAO Principal Investigator for the program. Mr. Robert Rasche is the SAO Program Manager and is responsible for day-to-day program management at SAO and coordination with GSFC. The report summarizes the main areas of SAO activity. Most of the work has been done jointly with personnel from GSFC and Marshall Space Flight Center (MSFC). We describe SAO participation in these efforts. Under the Agreement, SAO performed work in seven major areas of activity. These areas related to: (1) Constellation X-ray Mission Facility Definition Team and Study Management; (2) Science Support; (3) Spectroscopy X-ray Telescope (SXT); (4) Systems Engineering; (5) Travel in Support of the Work Effort; and (6) In-house Management and Coordination.

  18. Realistic Covariance Prediction for the Earth Science Constellation

    NASA Technical Reports Server (NTRS)

    Duncan, Matthew; Long, Anne

    2006-01-01

    Routine satellite operations for the Earth Science Constellation (ESC) include collision risk assessment between members of the constellation and other orbiting space objects. One component of the risk assessment process is computing the collision probability between two space objects. The collision probability is computed using Monte Carlo techniques as well as by numerically integrating relative state probability density functions. Each algorithm takes as inputs state vector and state vector uncertainty information for both objects. The state vector uncertainty information is expressed in terms of a covariance matrix. The collision probability computation is only as good as the inputs. Therefore, to obtain a collision calculation that is a useful decision-making metric, realistic covariance matrices must be used as inputs to the calculation. This paper describes the process used by the NASA/Goddard Space Flight Center's Earth Science Mission Operations Project to generate realistic covariance predictions for three of the Earth Science Constellation satellites: Aqua, Aura and Terra.

  19. Analysis of a Constellation Lab Cooperative Learning Activity

    NASA Astrophysics Data System (ADS)

    Gauthier, A. J.

    2001-12-01

    A cooperative learning activity was designed for use in the undergraduate laboratory course Introduction to Astronomical Observation. This group exercise enhances the student's learning of constellations and will hopefully increase retention of the material throughout the semester. It also serves as an "ice-breaker" during the first week of lab, promoting student involvement and vested interest in the course. To gain some insight into the student mind, a survey was conducted to evaluate the usefulness and overall opinion of this method. The students who completed the survey had previously been enrolled in a pre-requisite astronomy course that also required a constellation lab. In this previous course they "learned" the constellations from an instructor and a flashlight beam, studied them on their own, and then promptly took a quiz. Both methods are analyzed from an instructional designer's point of view and suggestions for future activities are presented. The preliminary results and accompanying activity will be discussed in poster and hand-out medium.

  20. The CEOS Atmospheric Composition Constellation (ACC), an Integrated Observing System

    NASA Astrophysics Data System (ADS)

    Hilsenrath, E.; Langen, J.; Zehner, C.

    2008-05-01

    The Atmospheric Composition (AC) Constellation is one of four pilot projects initiated by the Committee for Earth Observations Systems (CEOS) to bring about technical/scientific cooperation among space agencies that meet the goals of GEO and comply with the CEOS member agencies national programs. The Constellation concept has been endorsed in the GEO Work Plan, 2007-2009. The AC Constellation goal is to collect and deliver data to develop and improve monitoring, assessment and predictive capabilities for changes in the ozone layer, air quality and climate forcing associated with changes in the environment. These data will support five of the nine GEO SBAs: Health, Energy, Climate, Hazards, and Ecosystems. At the present time ESA, EC, CSA, CNES, JAXA, DLR, NIVR, NASA, NOAA and Eumetsat are participating in the Constellation study, and have major assets in orbit including 17 instruments on seven platforms. One goal of the Constellation study is to identify missing capabilities that will result when the present orbiting research satellites missions end and those not included in the next generation operational missions. Missing observations include very accurate and high spatial resolution measurements needed to be to track trends in atmospheric composition and understand their relationship to climate change. The following are the top level objectives for the AC Constellation Concept Study: • Develop a virtual constellation of existing and upcoming missions using synergies among the instruments and identify missing capabilities. • Study advanced architecture with new space assets and varying orbits with expectations that new technology could also be brought forward to best meet user requirements • Data system interoperability to insure that data are useful, properly targeted, and easily accessible. To demonstrate that the Constellation concept can provide value added data products, the ACC has initiated the three projects that are being supported by the

  1. EOS Terra: Mission Status Constellation MOWG

    NASA Technical Reports Server (NTRS)

    Mantziaras, Dimitrios

    2016-01-01

    This EOS Terra Mission Status Constellation MOWG will discuss mission summary; spacecraft subsystems summary, recent and planned activities; inclination adjust maneuvers, conjunction history, propellant usage and lifetime estimate; and end of mission plan.

  2. Quest Trial Q348: Evaluation of WaMoS II Data

    DTIC Science & Technology

    2013-04-01

    and slam warning.” Quest Sea Trial Q348 page 7 “In July of 2011, as part of the 11gi project, DRDC acquired and installed a new WaMoS...Fourier series expansion was originally implemented to compare WaMoS II data to reference data of an airborne LIDAR scanner, which yielded very good

  3. Human Systems Integration (HSI) Case Studies from the NASA Constellation Program

    NASA Technical Reports Server (NTRS)

    Baggerman, Susan; Berdich, Debbie; Whitmore, Mihriban

    2009-01-01

    The National Aeronautics and Space Administration (NASA) Constellation Program is responsible for planning and implementing those programs necessary to send human explorers back to the moon, onward to Mars and other destinations in the solar system, and to support missions to the International Space Station. The Constellation Program has the technical management responsibility for all Constellation Projects, including both human rated and non-human rated vehicles such as the Crew Exploration Vehicle, EVA Systems, the Lunar Lander, Lunar Surface Systems, and the Ares I and Ares V rockets. With NASA s new Vision for Space Exploration to send humans beyond Earth orbit, it is critical to consider the human as a system that demands early and continuous user involvement, inclusion in trade offs and analyses, and an iterative "prototype/test/ redesign" process. Personnel at the NASA Johnson Space Center are involved in the Constellation Program at both the Program and Project levels as human system integrators. They ensure that the human is considered as a system, equal to hardware and software vehicle systems. Systems to deliver and support extended human habitation on the moon are extremely complex and unique, presenting new opportunities to employ Human Systems Integration, or HSI practices in the Constellation Program. The purpose of the paper is to show examples of where human systems integration work is successfully employed in the Constellation Program and related Projects, such as in the areas of habitation and early requirements and design concepts.

  4. The NASA EV-2 CYGNSS Small Satellite Constellation Mission

    NASA Astrophysics Data System (ADS)

    Ruf, C. S.; Gleason, S.; Jelenak, Z.; Katzberg, S. J.; Ridley, A. J.; Rose, R.; Scherrer, J.; Zavorotny, V.

    2012-12-01

    The NASA EV-2 Cyclone Global Navigation Satellite System (CYGNSS) is a spaceborne mission focused on tropical cyclone (TC) inner core process studies. CYGNSS attempts to resolve the principle deficiencies with current TC intensity forecasts, which lies in inadequate observations and modeling of the inner core. The inadequacy in observations results from two causes: 1) Much of the inner core ocean surface is obscured from conventional remote sensing instruments by intense precipitation in the eye wall and inner rain bands. 2) The rapidly evolving (genesis and intensification) stages of the TC life cycle are poorly sampled in time by conventional polar-orbiting, wide-swath surface wind imagers. CYGNSS is specifically designed to address these two limitations by combining the all-weather performance of GNSS bistatic ocean surface scatterometry with the sampling properties of a constellation of satellites. The use of a dense constellation of nanosatellite results in spatial and temporal sampling properties that are markedly different from conventional imagers. Simulation studies will be presented which examine the sampling as functions of various orbit parameters of the constellation. Historical records of actual TC storm tracks are overlaid onto a simulated time series of the surface wind sampling enabled by the constellation. For comparison purposes, a similar analysis is conducted using the sampling properties of several past and present conventional spaceborne ocean wind scatterometers. Differences in the ability of the sensors to resolve the evolution of the TC inner core are examined. The spacecraft and constellation mission are described. The signal-to-noise ratio of the measured scattered signal and the resulting uncertainty in retrieved surface wind speed are also examined.

  5. Constellation Commodities Studies Summary

    NASA Technical Reports Server (NTRS)

    Dirschka, Eric

    2011-01-01

    Constellation program was NASA's long-term program for space exploration. The goal of the commodities studies was to solicit industry expertise in production, storage, and transportation required for future use and to improve efficiency and life cycle cost over legacy methods. Objectives were to consolidate KSC, CCAFS and other requirements; extract available industry expertise; identify commercial opportunities; and establish synergy with State of Florida partnerships. Study results are reviewed.

  6. RadNet Air Data From Olympia, WA

    EPA Pesticide Factsheets

    This page presents radiation air monitoring and air filter analysis data for Olympia, WA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  7. RadNet Air Data From Seattle, WA

    EPA Pesticide Factsheets

    This page presents radiation air monitoring and air filter analysis data for Seattle, WA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  8. RadNet Air Data From Ellensburg, WA

    EPA Pesticide Factsheets

    This page presents radiation air monitoring and air filter analysis data for Ellensburg, WA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  9. RadNet Air Data From Spokane, WA

    EPA Pesticide Factsheets

    This page presents radiation air monitoring and air filter analysis data for Spokane, WA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  10. On the optimum signal constellation design for high-speed optical transport networks.

    PubMed

    Liu, Tao; Djordjevic, Ivan B

    2012-08-27

    In this paper, we first describe an optimum signal constellation design algorithm, which is optimum in MMSE-sense, called MMSE-OSCD, for channel capacity achieving source distribution. Secondly, we introduce a feedback channel capacity inspired optimum signal constellation design (FCC-OSCD) to further improve the performance of MMSE-OSCD, inspired by the fact that feedback channel capacity is higher than that of systems without feedback. The constellations obtained by FCC-OSCD are, however, OSNR dependent. The optimization is jointly performed together with regular quasi-cyclic low-density parity-check (LDPC) code design. Such obtained coded-modulation scheme, in combination with polarization-multiplexing, is suitable as both 400 Gb/s and multi-Tb/s optical transport enabling technology. Using large girth LDPC code, we demonstrate by Monte Carlo simulations that a 32-ary signal constellation, obtained by FCC-OSCD, outperforms previously proposed optimized 32-ary CIPQ signal constellation by 0.8 dB at BER of 10(-7). On the other hand, the LDPC-coded 16-ary FCC-OSCD outperforms 16-QAM by 1.15 dB at the same BER.

  11. 78 FR 50094 - Notice of Inventory Completion: Maxey Museum, Walla Walla, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... of the Maxey Museum, Walla Walla, WA. The human remains were removed from the Whitman College Biology... the Biology Department at Whitman College, in Walla Walla County, WA, the Biology Department asked the Maxey Museum at Whitman College to determine whether any of the human remains in the Biology Department...

  12. Learning Curve for Teaching Constellations in a Planetarium

    NASA Astrophysics Data System (ADS)

    Hintz, Eric G.; Smith, N.; Moody, J. W.; Stephens, D. C.; Joner, M. D.; Hintz, M.; Lawler, J.; Jones, M.; Bench, N.

    2014-01-01

    As part of a larger project we have examined how students learn constellations in a planetarium environment. Students in our introductory descriptive astronomy class were given a 50 object quiz before any instruction. This quiz includes 30 constellations, 17 bright stars, two star clusters, and the Orion Nebula. In addition we gathered a small set of demographic information. After the initial quiz we tracked student scores through the semester to see how long it took for them to learn all 50 objects. We also plan to give a follow-up constellation quiz to students who have previously taken the quiz to test for retention. This will cover a time line for 6 months up to 4 years. We will present our early results from this study. This data will also be used as a baseline for a study of Head Mounted Displays to teach a deaf audience in a planetarium. This work is partially supported by funding from the National Science Foundation grant IIS-1124548 and the Sorenson Foundation.

  13. Imaging sensor constellation for tomographic chemical cloud mapping.

    PubMed

    Cosofret, Bogdan R; Konno, Daisei; Faghfouri, Aram; Kindle, Harry S; Gittins, Christopher M; Finson, Michael L; Janov, Tracy E; Levreault, Mark J; Miyashiro, Rex K; Marinelli, William J

    2009-04-01

    A sensor constellation capable of determining the location and detailed concentration distribution of chemical warfare agent simulant clouds has been developed and demonstrated on government test ranges. The constellation is based on the use of standoff passive multispectral infrared imaging sensors to make column density measurements through the chemical cloud from two or more locations around its periphery. A computed tomography inversion method is employed to produce a 3D concentration profile of the cloud from the 2D line density measurements. We discuss the theoretical basis of the approach and present results of recent field experiments where controlled releases of chemical warfare agent simulants were simultaneously viewed by three chemical imaging sensors. Systematic investigations of the algorithm using synthetic data indicate that for complex functions, 3D reconstruction errors are less than 20% even in the case of a limited three-sensor measurement network. Field data results demonstrate the capability of the constellation to determine 3D concentration profiles that account for ~?86%? of the total known mass of material released.

  14. System Constellations as a Tool Supporting Organisational Learning and Change Processes

    ERIC Educational Resources Information Center

    Birkenkrahe, Marcus

    2008-01-01

    Originally developed in the context of family therapy, system constellations are introduced using an organisational learning and system theoretical framework. Constellations are systemic group interventions using a spatial representation of the system elements. They correspond to deutero-learning processes and use higher-order systemic thinking.…

  15. 76 FR 70649 - Safety Zone; Department of Defense Exercise, Hood Canal, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-15

    ...-AA00 Safety Zone; Department of Defense Exercise, Hood Canal, WA AGENCY: Coast Guard, DHS. ACTION... involved in a Department of Defense exercise in Hood Canal, WA that will take place on November 21, 2011. A... would end. These Department of Defense (DOD) vessels have an important and urgent need to perform this...

  16. 76 FR 69131 - Drawbridge Operation Regulation; Lake Washington Ship Canal, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... Operation Regulation; Lake Washington Ship Canal, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of... Bridge across the Lake Washington Ship Canal, mile 0.1, at Seattle, WA. The deviation is necessary to... Bascule Bridge across the Lake Washington Ship Canal, mile 0.1, for vessel traffic for a 14 day period to...

  17. 77 FR 43513 - Olympia Harbor Days Tug Boat Races, Budd Inlet, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... Harbor Days Tug Boat Races, Budd Inlet, WA AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of regulation. SUMMARY: The Coast Guard will enforce the Special Local Regulation, Olympia Harbor Days Tug Boat... Special Local Regulation for Olympia Harbor Days Tug Boat Races, Budd Inlet, WA in 33 CFR 100.1309 on...

  18. 76 FR 38011 - Safety Zone; Hylebos Bridge Restoration, Hylebos Waterway, Tacoma, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ...-AA00 Safety Zone; Hylebos Bridge Restoration, Hylebos Waterway, Tacoma, WA AGENCY: Coast Guard, DHS... extending 50 yards to the north and south of the Hylebos Bridge, Tacoma, WA in both directions along the entire length of the Hylebos Bridge to ensure the safety of the boating public during the Hylebos Bridge...

  19. End-of-Mission Planning Challenges for a Satellite in a Constellation

    NASA Technical Reports Server (NTRS)

    Boain, Ronald J.

    2013-01-01

    At the end of a mission, satellites embedded in a constellation must first perform propulsive maneuvers to safely exit the constellation before they can begin with the usual end-of-mission activities: deorbit, passivation, and decommissioning. The target orbit for these exit maneuvers must be sufficiently below the remaining constellation satellites such that, once achieved, there is no longer risk of close conjunctions. Yet, the exit maneuvers must be done based on the spacecraft's state of health and operational capability when the decision to end the mission is made. This paper focuses on the recently developed exit strategy for the CloudSat mission to highlight problems and issues, which forced the discarding of CloudSat's original EoM Plan and its replacement with a new plan consistent with changes to the spacecraft's original operational mode. The analyses behind and decisions made in formulating this new exit strategy will be of interest to other missions in a constellation currently preparing to update their End-of-Mission Plan.

  20. Monitoring of Arctic Conditions from a Virtual Constellation of Synthetic Aperture Radar Satellites

    DTIC Science & Technology

    2014-09-30

    Constellation of Synthetic Aperture Radar Satellites RSMAS – Department of Ocean Sciences Center for Southeastern Tropical Advanced Remote Sensing...fax: (305) 421-4696 email: pminnett@rsmas.miami.edu Award Number: N00014-12-1-0448 LONG-TERM GOALS Utilize a constellation of satellite...OBJECTIVES a) Provide daily Arctic situational awareness from the CSTARS SAR satellite constellation . b) Develop a Neural Network algorithm for ice-type

  1. Anthropometric Requirements for Constellation

    NASA Technical Reports Server (NTRS)

    Raulu, Sudhakar; Margerum, Sarah; Dory, Jonathan; Rochlis, Jennifer

    2009-01-01

    This slide presentation reviews the requirement from an Anthropometric standpoint for the development of the Constellation's programs hardware, specifically the Orion crew exploration vehicle. The NASA JSC Anthropometry and Biomechanics Facility (ABF) provides anthropometry, strength, mobility, and mass properties requirements; gathers, interprets, manages and maintains the flight crew anthropometry database; and participates and provides input during crew selection. This is used to assist in requirements for vehicle and space suit design and for crew selection.

  2. SAC-C Mission and the Morning Constellation

    NASA Astrophysics Data System (ADS)

    Colomb, F. R.; Alonso, C.; Hofmann, C.; Frulla, L.; Nollmann, I.; Milovich, J.; Kuba, J.; Ares, F.; Kalemkarian, M.

    2002-01-01

    components (ICARE), provided by CNES will permit improvement of risk estimation models for radiation effect on last generation integrated circuit technology. . On June 14th, 2000 CONAE and NASA signed an amendment to the Memorandum of Understanding for the SAC-C mission in order that the SAC-C satellite, were included in a constellation - named "Morning Constellation". It is integrated by USA satellites Landsat 7, EO 1, Terra, and Argentine SAC-C that feature on-board instruments from the United States, Argentina, Denmark, Italy, France, and Japan. The four satellite tracks on the Earth's surface are the same, their orbital height being 705 km and their inclination, 98.21 degrees. They cross the Equator at 10:00, 10:01, 10:15, and 10:30 hours, respectively (local time). Satellites comply with the World Wide Reference System. The Constellation has been working since March 2001 as a single mission and several cooperative activities have been undertaken and will be presented in this paper. Several jointly sponsored technical workshops have been held, and also collaborative spacecraft navigation experiments have been made. One of the objectives of the AM Constellation is the collaboration in the case of emergencies, NASA and CONAE agreed to give preference in those situation in the planification of their satellite acquisitions. From all the possible hazardous events, the most important for the country are fire and floods. In relation to fires, CONAE is presently adapting and developing the algorithms for using MODIS data to generate a fire map product. Additionally research on fire detection is carried out using the data from the HSTC camera. In relation to flooding, CONAE works in cooperation to national institutions providing the data and, in some cases, producing flood extent maps. In particular MMRS data is demonstrating to be very effective due to its spectral and radiometric resolutions, and its large swath which is well suited for extended countries like Argentina.

  3. Genotype 3 is the predominant hepatitis C genotype in a multi-ethnic Asian population in Malaysia.

    PubMed

    Ho, Shiaw-Hooi; Ng, Kee-Peng; Kaur, Harvinder; Goh, Khean-Lee

    2015-06-01

    Genotypes of hepatitis C virus (HCV) are distributed differently across the world. There is a paucity of such data in a multi-ethnic Asian population like Malaysia. The objectives of this study were to determine the distribution of HCV genotypes between major ethnic groups and to ascertain their association with basic demographic variables like age and gender. This was a cross-sectional prospective study conducted from September 2007 to September 2013. Consecutive patients who were detected to have anti-HCV antibodies in the University of Malaya Medical Centre were included and tested for the presence of HCV RNA using Roche Cobas Amplicor Analyzer and HCV genotype using Roche single Linear Array HCV Genotyping strip. Five hundred and ninety-six subjects were found to have positive anti-HCV antibodies during this period of time. However, only 396 (66.4%) were HCV RNA positive and included in the final analysis. Our results showed that HCV genotype 3 was the predominant genotype with overall frequency of 61.9% followed by genotypes 1 (35.9%), 2 (1.8%) and 6 (0.5%). There was a slightly higher prevalence of HCV genotype 3 among the Malays when compared to the Chinese (P=0.043). No other statistical significant differences were observed in the distribution of HCV genotypes among the major ethnic groups. There was also no association between the predominant genotypes and basic demographic variables. In a multi-ethnic Asian society in Malaysia, genotype 3 is the predominant genotype among all the major ethnic groups with genotype 1 as the second commonest genotype. Both genotypes 2 and 6 are uncommon. Neither genotype 4 nor 5 was detected. There is no identification of HCV genotype according to ethnic origin, age and gender.

  4. Prehistory of Zodiac Dating: Three Strata of Upper Paleolithic Constellations

    NASA Astrophysics Data System (ADS)

    Gurshtein, Alex A.

    A pattern of archaic proto-constellations is extracted from Aratus' "The Phaenomena" didactic poem list according to a size criterion elaborated earlier, and their symbolism is analyzed. As a result of this approach three celestial symbolical strata are discovered to be probably a reflection of the symbols for the Lower, the Middle and the Upper Worlds; the Under-World creatures have a water character, the Middle World ones are mostly anthropomorphic and flying beings are for the Upper World. The strata excerpted from Aratus' sky seems to be in agreement with the well-known Babylonian division into three god pathways for Ea (Enki), Anu and Enlil. There is a possibility of dating the pattern discovered because of precession's strong influence as far back as 16 thousand years, the result being supported by the comparison of different star group mean sizes. The archaic constellation pattern under consideration is a reasonable background of symbolical meanings for the first Zodiacal generation quartet (7.5 thousand years old) examined by the author previously. The enormous size of the Argo constellation (Ship of Argo and his Argonauts) as well as the large sizes of other southern constellations are explained as due to the existence of an accumulation zone near the South celestial pole. Some extra correlations between the reconstruction proposed and cultural data available are discussed. The paper is the second part of the investigation "On the Origin of the Zodiacal constellations" published in Vistas in Astronomy, vol.36, pp.171-190, 1993.

  5. Exploring the Architectural Tradespace of Severe Weather Monitoring Nanosatellite Constellations

    NASA Astrophysics Data System (ADS)

    Hitomi, N.; Selva, D.; Blackwell, W. J.

    2014-12-01

    MicroMAS-1, a 3U nanosatellite developed by MIT/LL, MIT/SSL, and University of Massachusetts, was launched on July 13, 2014 and is scheduled for deployment from the International Space Station in September. The development of MicroMAS motivates an architectural analysis of a constellation of nanosatellites with the goal of drastically reducing the cost of observing severe storms compared with current monolithic missions such as the Precision and All-Weather Temperature and Humidity (PATH) mission from the NASA Decadal Survey. Our goal is to evolve the instrument capability on weather monitoring nanosatellites to achieve higher performance and better satisfy stakeholder needs. Clear definitions of performance requirements are critical in the conceptual design phase when much of the project's lifecycle cost and performance will be fixed. Ability to perform trade studies and optimization of performance needs with instrument capability will enable design teams to focus on key technologies that will introduce high value and high return on investment. In this work, we approach the significant trades and trends of constellations for monitoring severe storms by applying our rule-based decision support tool. We examine a subset of stakeholder groups listed in the OSCAR online database (e.g., weather, climate) that would benefit from severe storm weather data and their respective observation requirements (e.g. spatial resolution, accuracy). We use ten parameters in our analysis, including atmospheric temperature, humidity, and precipitation. We compare the performance and cost of thousands of different possible constellations. The constellations support hyperspectral sounders that cover different portions of the millimeter-wave spectrum (50-60 GHz, 118GHz, 183GHz) in different orbits, and the performance results are compared against those of the monolithic PATH mission. Our preliminary results indicate that constellations using the hyperspectral millimeter wave sounders can

  6. Risk to space sustainability from large constellations of satellites

    NASA Astrophysics Data System (ADS)

    Bastida Virgili, B.; Dolado, J. C.; Lewis, H. G.; Radtke, J.; Krag, H.; Revelin, B.; Cazaux, C.; Colombo, C.; Crowther, R.; Metz, M.

    2016-09-01

    The number of artificial objects in orbit continues to increase and, with it, a key threat to space sustainability. In response, space agencies have identified a set of mitigation guidelines aimed at enabling space users to reduce the generation of space debris by, for example, limiting the orbital lifetime of their spacecraft and launcher stages after the end of their mission. Planned, large constellations of satellites in low Earth orbit (LEO), though addressing the lack of basic internet coverage in some world regions, may disrupt the sustainability of the space environment enabled by these mitigation practices. We analyse the response of the space object population to the introduction of a large constellation conforming to the post-mission disposal guideline with differing levels of success and with different disposal orbit options. The results show that a high success rate of post-mission disposal by constellation satellites is a key driver for space sustainability.

  7. 33 CFR 100.1307 - Special Local Regulations, Strait Thunder Performance, Port Angeles, WA.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Special Local Regulations, Strait Thunder Performance, Port Angeles, WA. 100.1307 Section 100.1307 Navigation and Navigable Waters COAST... § 100.1307 Special Local Regulations, Strait Thunder Performance, Port Angeles, WA. (a) Regulated Areas...

  8. 33 CFR 100.1307 - Special Local Regulations, Strait Thunder Performance, Port Angeles, WA.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Special Local Regulations, Strait Thunder Performance, Port Angeles, WA. 100.1307 Section 100.1307 Navigation and Navigable Waters COAST... § 100.1307 Special Local Regulations, Strait Thunder Performance, Port Angeles, WA. (a) Regulated Areas...

  9. 33 CFR 100.1307 - Special Local Regulations, Strait Thunder Performance, Port Angeles, WA.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Special Local Regulations, Strait Thunder Performance, Port Angeles, WA. 100.1307 Section 100.1307 Navigation and Navigable Waters COAST... § 100.1307 Special Local Regulations, Strait Thunder Performance, Port Angeles, WA. (a) Regulated Areas...

  10. 33 CFR 100.1307 - Special Local Regulations, Strait Thunder Performance, Port Angeles, WA.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Special Local Regulations, Strait Thunder Performance, Port Angeles, WA. 100.1307 Section 100.1307 Navigation and Navigable Waters COAST... § 100.1307 Special Local Regulations, Strait Thunder Performance, Port Angeles, WA. (a) Regulated Areas...

  11. 33 CFR 100.1307 - Special Local Regulations, Strait Thunder Performance, Port Angeles, WA.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Special Local Regulations, Strait Thunder Performance, Port Angeles, WA. 100.1307 Section 100.1307 Navigation and Navigable Waters COAST... § 100.1307 Special Local Regulations, Strait Thunder Performance, Port Angeles, WA. (a) Regulated Areas...

  12. The Science Goals of the Constellation-X Mission

    NASA Technical Reports Server (NTRS)

    White, Nicholas E.; Tananbaum, Harvey; Weaver, Kimberly; Petre, Robert; Bookbinder, Jay

    2004-01-01

    The Constellation-X mission will address the questions: "What happens to matter close to a black hole?" and "What is Dark Energy?" These questions are central to the NASA Beyond Einstein Program, where Constellation-X plays a central role. The mission will address these questions by using high throughput X-ray spectroscopy to observe the effects of strong gravity close to the event horizon of black holes, and to observe the formation and evolution of clusters of galaxies in order to precisely determine Cosmological parameters. To achieve these primary science goals requires a factor of 25-100 increase in sensitivity for high resolution spectroscopy. The mission will also perform routine high- resolution X-ray spectroscopy of faint and extended X-ray source populations. This will provide diagnostic information such as density, elemental abundances, velocity, and ionization state for a wide range of astrophysical problems. This has enormous potential for the discovery of new unexpected phenomena. The Constellation-X mission is a high priority in the National Academy of Sciences McKee-Taylor Astronomy and Astrophysics Survey of new Astrophysics Facilities for the first decade of the 21st century.

  13. Regional positioning using a low Earth orbit satellite constellation

    NASA Astrophysics Data System (ADS)

    Shtark, Tomer; Gurfil, Pini

    2018-02-01

    Global and regional satellite navigation systems are constellations orbiting the Earth and transmitting radio signals for determining position and velocity of users around the globe. The state-of-the-art navigation satellite systems are located in medium Earth orbits and geosynchronous Earth orbits and are characterized by high launching, building and maintenance costs. For applications that require only regional coverage, the continuous and global coverage that existing systems provide may be unnecessary. Thus, a nano-satellites-based regional navigation satellite system in Low Earth Orbit (LEO), with significantly reduced launching, building and maintenance costs, can be considered. Thus, this paper is aimed at developing a LEO constellation optimization and design method, using genetic algorithms and gradient-based optimization. The preliminary results of this study include 268 LEO constellations, aimed at regional navigation in an approximately 1000 km × 1000 km area centered at the geographic coordinates [30, 30] degrees. The constellations performance is examined using simulations, and the figures of merit include total coverage time, revisit time, and geometric dilution of precision (GDOP) percentiles. The GDOP is a quantity that determines the positioning solution accuracy and solely depends on the spatial geometry of the satellites. Whereas the optimization method takes into account only the Earth's second zonal harmonic coefficient, the simulations include the Earth's gravitational field with zonal and tesseral harmonics up to degree 10 and order 10, Solar radiation pressure, drag, and the lunisolar gravitational perturbation.

  14. An integrated hyperspectral and SAR satellite constellation for environment monitoring

    NASA Astrophysics Data System (ADS)

    Wang, Jinnian; Ren, Fuhu; Xie, Chou; An, Jun; Tong, Zhanbo

    2017-09-01

    A fully-integrated, Hyperspectral optical and SAR (Synthetic Aperture Radar) constellation of small earth observation satellites will be deployed over multiple launches from last December to next five years. The Constellation is expected to comprise a minimum of 16 satellites (8 SAR and 8 optical ) flying in two orbital planes, with each plane consisting of four satellite pairs, equally-spaced around the orbit plane. Each pair of satellites will consist of a hyperspectral/mutispectral optical satellite and a high-resolution SAR satellite (X-band) flying in tandem. The constellation is expected to offer a number of innovative capabilities for environment monitoring. As a pre-launch experiment, two hyperspectral earth observation minisatellites, Spark 01 and 02 were launched as secondary payloads together with Tansat in December 2016 on a CZ-2D rocket. The satellites feature a wide-range hyperspectral imager. The ground resolution is 50 m, covering spectral range from visible to near infrared (420 nm - 1000 nm) and a swath width of 100km. The imager has an average spectral resolution of 5 nm with 148 channels, and a single satellite could obtain hyperspectral imagery with 2.5 million km2 per day, for global coverage every 16 days. This paper describes the potential applications of constellation image in environment monitoring.

  15. 78 FR 38829 - Special Local Regulations; Seattle Seafair Hydroplane Race, Lake Washington, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-28

    ... Local Regulations; Seattle Seafair Hydroplane Race, Lake Washington, WA AGENCY: Coast Guard, DHS. ACTION... Hydroplane Race Special Local Regulation on Lake Washington, WA from 8 a.m. on August 2, 2013, through 11:59... restrict general navigation in the following area; The waters of Lake Washington bounded by the Interstate...

  16. Kilohoku Ho`okele Wa`a : Astronomy of the Hawaiian Navigators

    NASA Astrophysics Data System (ADS)

    Slater, Stephanie; Slater, Timothy F.; Baybayan, Kalepa C.

    2016-01-01

    This poster provides an introduction to the astronomy of the Hawaiian wayfinders, Kilohoku Ho`okele Wa`a. Rooted in a legacy of navigation across the Polynesian triangle, wayfinding astronomy has been part of a suite of skills that allows navigators to deliberately hop between the small islands of the Pacific, for thousands of years. Forty years ago, in one manifestation of the Hawaiian Renaissance, our teachers demonstrated that ancient Hawaiians were capable of traversing the wide Pacific to settle and trade on islands separated by thousands of miles. Today those same mentors train a new generation of navigators, making Hawaiian voyaging a living, evolving, sustainable endeavor. This poster presents two components of astronomical knowledge that all crewmen, but particularly those in training to become navigators, learn early in their training. Na Ohana Hoku, the Hawaiian Star Families constitute the basic units of the Hawaiian sky. In contrast to the Western system of 88 constellations, Na Ohana Hoku divides the sky into four sections that each run from the northern to the southern poles. This configuration reduces cognitive load, allowing the navigator to preserve working memory for other complex tasks. In addition, these configurations of stars support the navigator in finding and generatively using hundreds of individual, and navigationally important pairs of stars. The Hawaiian Star Compass divides the celestial sphere into a directional system that uses 32 rather than 8 cardinal points. Within the tropics, the rising and setting of celestial objects are consistent within the Hawaiian Star Compass, providing for extremely reliable direction finding. Together, Na Ohana Hoku and the Hawaiian Star Compass provide the tropical navigator with astronomical assistance that is not available to, and would have been unknown to Western navigators trained at higher latitudes.

  17. Simulating the Liaison Navigation Concept in a Geo + Earth-Moon Halo Constellation

    NASA Technical Reports Server (NTRS)

    Fujimoto, K.; Leonard, J. M.; McGranaghan, R. M.; Parker, J. S.; Anderson, R. L.; Born, G. H.

    2012-01-01

    Linked Autonomous Interplanetary Satellite Orbit Navigation, or LiAISON, is a novel satellite navigation technique where relative radiometric measurements between two or more spacecraft in a constellation are processed to obtain the absolute state of all spacecraft. The method leverages the asymmetry of the gravity field that the constellation exists in. This paper takes a step forward in developing a high fidelity navigation simulation for the LiAISON concept in an Earth-Moon constellation. In particular, we aim to process two-way Doppler measurements between a satellite in GEO orbit and another in a halo orbit about the Earth-Moon L1 point.

  18. Improved satellite constellations for CONUS ATC coverage

    DOT National Transportation Integrated Search

    1974-05-01

    The report examines the problem of designing a constellation of orbiting satellites capable of supporting an aircraft navigation/surveillance service over CONUS. It is assumed that the aircraft positions are determined by hyperbolic multilateration u...

  19. Multisatellite constellation configuration selection for multiregional highly elliptical orbit constellations

    NASA Technical Reports Server (NTRS)

    Matossian, Mark G.

    1994-01-01

    The Archimedes Project is a joint effort of the European Space Agency (ESA) and the National Space Development Agency of Japan (NASDA). The primary goal of the Archimedes project is to perform a technical feasibility analysis and preliminary design of a highly inclined multisatellite constellation for direct broadcast and mobile communications services for Europe, Japan and much of North America. This report addresses one aspect of this project, specifically an analysis of continuous satellite coverage using multiregional highly elliptical orbits (M-HEO's). The analysis methodology and ensuing software tool, named SPIFF, were developed specifically for this project by the author during the summer of 1992 under the STA/NSF Summer Institute in Japan Program at Tsukuba Space Center.

  20. Connect the Dots and Pinhole Constellations.

    ERIC Educational Resources Information Center

    Kominski, John

    1991-01-01

    Identifies a variety of methods to introduce constellations and asterisms to students in the classroom and planetarium prior to their study of the night sky. Materials used include transparencies, oatmeal boxes, photographic slides, and tracing paper. Exercises incorporate storytelling and prediction of location, movement, and seasonal patterns of…

  1. 76 FR 14829 - Safety Zone; 2011 Hylebos Bridge Restoration, Hylebos Waterway, Tacoma, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-18

    ...-AA00 Safety Zone; 2011 Hylebos Bridge Restoration, Hylebos Waterway, Tacoma, WA AGENCY: Coast Guard... temporary safety zone extending 50 yards to the north and south of the Hylebos Bridge, Tacoma, WA in both directions along the entire length of the Hylebos Bridge to ensure the safety of the boating public during...

  2. The power of inexpensive satellite constellations

    NASA Astrophysics Data System (ADS)

    Dyrud, Lars P.; La Tour, Rose; Swartz, William H.; Nag, Sreeja; Lorentz, Steven R.; Hilker, Thomas; Wiscombe, Warren J.; Papadakis, Stergios J.

    2014-06-01

    Two thematic drivers are motivating the science community towards constellations of small satellites, the revelation that many next generation system science questions are uniquely addressed with sufficient numbers of simultaneous space based measurements, and the realization that space is historically expensive, and in an environment of constrained costs, we must innovate to ―do more with less‖. We present analysis that answers many of the key questions surrounding constellations of scientific satellites, including research that resulted from the GEOScan community based effort originally intended as hosted payloads on Iridium NEXT. We present analysis that answers the question how many satellites does global system science require? Perhaps serendipitously, the analyses show that many of the key science questions independently converge towards similar results, i.e. that approximately 60+ satellites are needed for transformative, as opposed to incremental capability in system science. The current challenge is how to effectively transition products from design to mass production for space based instruments and vehicles. Ideally, the lesson learned from past designs and builds of various space products should pave the way toward a better manufacturing plan that utilizes just a fraction of the prototype`s cost. Using the commercial products industry implementations of mass customization as an example, we will discuss about the benefits of standardization in design requirements for space instruments and vehicles. For example, the instruments (payloads) are designed to have standardized elements, components, or modules that interchangeably work together within a linkage system. We conclude with a discussion on implementation plans and the new paradigms for community and international cooperation enabled by small satellite constellations.

  3. Optimizing the Attitude Control of Small Satellite Constellations for Rapid Response Imaging

    NASA Astrophysics Data System (ADS)

    Nag, S.; Li, A.

    2016-12-01

    Distributed Space Missions (DSMs) such as formation flight and constellations, are being recognized as important solutions to increase measurement samples over space and time. Given the increasingly accurate attitude control systems emerging in the commercial market, small spacecraft now have the ability to slew and point within few minutes of notice. In spite of hardware development in CubeSats at the payload (e.g. NASA InVEST) and subsystems (e.g. Blue Canyon Technologies), software development for tradespace analysis in constellation design (e.g. Goddard's TAT-C), planning and scheduling development in single spacecraft (e.g. GEO-CAPE) and aerial flight path optimizations for UAVs (e.g. NASA Sensor Web), there is a gap in open-source, open-access software tools for planning and scheduling distributed satellite operations in terms of pointing and observing targets. This paper will demonstrate results from a tool being developed for scheduling pointing operations of narrow field-of-view (FOV) sensors over mission lifetime to maximize metrics such as global coverage and revisit statistics. Past research has shown the need for at least fourteen satellites to cover the Earth globally everyday using a LandSat-like sensor. Increasing the FOV three times reduces the need to four satellites, however adds image distortion and BRDF complexities to the observed reflectance. If narrow FOV sensors on a small satellite constellation were commanded using robust algorithms to slew their sensor dynamically, they would be able to coordinately cover the global landmass much faster without compensating for spatial resolution or BRDF effects. Our algorithm to optimize constellation satellite pointing is based on a dynamic programming approach under the constraints of orbital mechanics and existing attitude control systems for small satellites. As a case study for our algorithm, we minimize the time required to cover the 17000 Landsat images with maximum signal to noise ratio fall

  4. 76 FR 66054 - Exelon Corporation Constellation Energy Group, Inc.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-25

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EC11-83-001] Exelon Corporation Constellation Energy Group, Inc.; Notice of Filing Take notice that, on October 11, 2011, Exelon Corporation and Constellation Energy Group, Inc. (Merger Applicants) submitted a filing styled as an answer in...

  5. BENTHIC MACROFAUNA-HABITAT RELATIONSHIPS IN WILLAPA BAY, WA

    EPA Science Inventory

    Benthic macrofauna-habitat relationships were determined estuary-wide in Willapa Bay, WA for four intertidal habitats ((1) eelgrass, Zostera marina, (2) Atlantic cordgrass, Spartina alterniflora, (3) ghost shrimp, Neotrypaea californiensis, (4) mud shrimp, Upogebia pugettensis) i...

  6. The GeoEye Satellite Constellation

    NASA Technical Reports Server (NTRS)

    Dial, Gene; Cole, Aaron; Lutes, James; McKune, John; Martinez, Mike; Rao, R. S.; Taylor, Martin

    2007-01-01

    The GeoEye Constellation consists of: a) IKONOS and OrbView-3 for high resolution; b) GeoEye with higher resolution 1Q2007; c) RESOUCESAT-1 for global crop assessment; d) OrbView-2 for ocean research and fish. IKONOS performance in 2005 included stable image quality, radiometry and geometric accuracy. reliability is 80% to 2008. Demonstrated capacity for high-volume, quick-response collection and production.

  7. Constellation Program Lessons Learned in the Quantification and Use of Aerodynamic Uncertainty

    NASA Technical Reports Server (NTRS)

    Walker, Eric L.; Hemsch, Michael J.; Pinier, Jeremy T.; Bibb, Karen L.; Chan, David T.; Hanke, Jeremy L.

    2011-01-01

    The NASA Constellation Program has worked for the past five years to develop a re- placement for the current Space Transportation System. Of the elements that form the Constellation Program, only two require databases that define aerodynamic environments and their respective uncertainty: the Ares launch vehicles and the Orion crew and launch abort vehicles. Teams were established within the Ares and Orion projects to provide repre- sentative aerodynamic models including both baseline values and quantified uncertainties. A technical team was also formed within the Constellation Program to facilitate integra- tion among the project elements. This paper is a summary of the collective experience of the three teams working with the quantification and use of uncertainty in aerodynamic environments: the Ares and Orion project teams as well as the Constellation integration team. Not all of the lessons learned discussed in this paper could be applied during the course of the program, but they are included in the hope of benefiting future projects.

  8. Science Opportunities Enabled by NASA's Constellation System: Interim Report

    NASA Astrophysics Data System (ADS)

    Committee On Science Opportunities Enabled By Nasa'S Constellation System, National Research Council

    To begin implementation of the Vision for Space Exploration (recently renamed "United States Space Exploration Policy"), NASA has begun development of new launch vehicles and a human-carrying spacecraft that are collectively called the Constellation System. In November 2007, NASA asked the NRC to evaluate the potential for the Constellation System to enable new space science opportunities. For this interim report, 11 existing "Vision Mission" studies of advanced space science mission concepts inspired by earlier NASA forward-looking studies were evaluated. The focus was to assess the concepts and group them into two categories: more-deserving or less deserving of future study. This report presents a description of the Constellation System and its opportunities for enabling new space science opportunities, and a systematic analysis of the 11 Vision Mission studies. For the final report, the NRC issued a request for information to the relevant communities to obtain ideas for other mission concepts that will be assessed by the study committee, and several issues addressed only briefly in the interim report will be explored more fully.

  9. 75 FR 23804 - Notice of Inventory Completion: Paul H. Karshner Memorial Museum, Puyallup, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ... made by the Paul H. Karshner Memorial Museum professional staff in consultation with representatives of... Memorial Museum, Puyallup, WA AGENCY: National Park Service, Interior. ACTION: Notice. Notice is here given... Memorial Museum, Puyallup, WA. The human remains were removed from the Aleutian Islands, AK. This notice is...

  10. Small Satellite Constellations: The Future for Operational Earth Observation

    NASA Technical Reports Server (NTRS)

    Stephens, J. Paul

    2007-01-01

    Nanosat, microsat and minisat are low-cost, rapid-response small-satellites built from advanced terrestrial technology. SSTL delivers the benefits of affordable access to space through low-cost, rapid response, small satellites designed and built with state-of-the-art COTS technologies by: a) reducing the cost of entry into space; b) Achieving more missions within fixed budgets; c) making constellations and formation flying financially viable; d) responding rapidly from initial concept to orbital operation; and e) bringing the latest industrial COTS component advances to space. Growth has been stimulated in constellations for high temporal revisit&persistent monitoring and military responsive space assets.

  11. Proton conductivity and methanol permeability of Nafion-SiO2/SiWA composite membranes

    NASA Astrophysics Data System (ADS)

    Thiam, Hui San; Chia, Min Yan; Cheah, Qiao Rou; Koo, Charlene Chai Hoon; Lai, Soon Onn; Chong, Kok Chung

    2017-04-01

    Proton exchange membranes for a direct methanol fuel cell (DMFC) were prepared by incorporating silica/silicotungstic acid (SiO2/SiWA) inorganic composite into a Nafion polymer. The effects of SiO2/SiWA content on proton conductivity of membranes were investigated by using a four-probe conductivity cell. Methanol permeability of composite membrane was also determined by using a homemade diffusion cell and gas chromatography technique. It was found that proton conductivity of the composite membranes decreased with SiO2/SiWA content, however the highest proton conductivity achieved was 11% greater than the pure recast Nafion membrane. The methanol permeability of composite membrane was much lower than that of pure recast Nafion, in a reduction of 58% which indicated a better resistance to fuel crossover. Nafion-SiO2/SiWA composite membrane showed promising advantages over pure Nafion on electrochemical properties such as proton conductivity and fuel crossover and it is potentially attractive for use in DMFC.

  12. Drug policy constellations: A Habermasian approach for understanding English drug policy.

    PubMed

    Stevens, Alex; Zampini, Giulia Federica

    2018-07-01

    It is increasingly accepted that a view of policy as a rational process of fitting evidence-based means to rationally justified ends is inadequate for understanding the actual processes of drug policy making. We aim to provide a better description and explanation of recent English drug policy decisions. We develop the policy constellation concept from the work of Habermas, in dialogue with data from two contemporary debates in English policy; on decriminalisation of drug possession and on recovery in drug treatment. We collect data on these debates through long-term participant observation, stakeholder interviews (n = 15) and documentary analysis. We show the importance of social asymmetries in power in enabling structurally advantaged groups to achieve the institutionalisation of their moral preferences as well as the reproduction of their social and economic power through the deployment of policies that reflect their material interests and normative beliefs. The most influential actors in English drug policy come together in a 'medico-penal constellation', in which the aims and practices of public health and social control overlap. Formal decriminalisation of possession has not occurred, despite the efforts of members of a challenging constellation which supports it. Recovery was put forward as the aim of drug treatment by members of a more powerfully connected constellation. It has been absorbed into the practice of 'recovery-oriented' drug treatment in a way that maintains the power of public health professionals to determine the form of treatment. Actors who share interests and norms come together in policy constellations. Strategic action within and between constellations creates policies that may not take the form that was intended by any individual actor. These policies do not result from purely rational deliberation, but are produced through 'systematically distorted communication'. They enable the most structurally favoured actors to institutionalise

  13. A Gene Constellation in Avian Influenza A (H7N9) Viruses May Have Facilitated the Fifth Wave Outbreak in China.

    PubMed

    Zhu, Wenfei; Dong, Jie; Zhang, Ye; Yang, Lei; Li, Xiyan; Chen, Tao; Zhao, Xiang; Wei, Hejiang; Bo, Hong; Zeng, Xiaoxu; Huang, Weijuan; Li, Zi; Tang, Jing; Zhou, Jianfang; Gao, Rongbao; Xin, Li; Yang, Jing; Zou, Shumei; Chen, Wenbing; Liu, Jia; Shu, Yuelong; Wang, Dayan

    2018-04-17

    The 2016-2017 epidemic of influenza A (H7N9) virus in China prompted concern that a genetic change may underlie increased virulence. Based on an evolutionary analysis of H7N9 viruses from all five outbreak waves, we find that additional subclades of the H7 and N9 genes have emerged. Our analysis indicates that H7N9 viruses inherited NP genes from co-circulating H7N9 instead of H9N2 viruses. Genotypic diversity among H7N9 viruses increased following wave I, peaked during wave III, and rapidly deceased thereafter with minimal diversity in wave V, suggesting that the viruses entered a relatively stable evolutionary stage. The ZJ11 genotype caused the majority of human infections in wave V. We suggest that the largest outbreak of wave V may be due to a constellation of genes rather than a single mutation. Therefore, continuous surveillance is necessary to minimize the threat of H7N9 viruses. Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.

  14. How to Enter, Fly In, and Exit the A-Train Constellation

    NASA Technical Reports Server (NTRS)

    Vincent, Mark A.

    2015-01-01

    The collaborative science obtained from the satellites in the A-Train is an unparalleled success. The constellation framework that has evolved is well-formulated and documented by its international members. Communication between teams is enhanced by a web-based Constellation Coordination System. Safety and correlated observations are ensured by defining independent control boxes with buffers in between. Each mission stays within its control box by regular drag makeup maneuvers. Annual inclination adjustments are coordinated by all missions to maintain their absolute and relative Mean Local Time of Ascending Node (MLTAN). Since the satellites are in different orbit planes their separation involves a three-dimensional triad made up of the along track separations, reference groundtracks and MLTAN's. For further safety, a Constellation Envelope has been defined to determine safe entry and exit orbits.

  15. Evidence for presumable feline origin of sporadic G6P[9] rotaviruses in humans.

    PubMed

    Pietsch, Corinna; Liebert, Uwe G

    2018-05-31

    Species A rotaviruses are highly diverse and impose a substantial burden to human and animal health. Interspecies transmission between livestock, domestic animals and humans is commonly observed, but spread of animal-like rotaviruses within the human population is limited. During the continued monitoring of rotavirus strains in Germany, an unusual G6P[9] rotavirus strain was detected in feces of a child. The complete rotavirus coding sequences revealed a unique G6-P[9]-I2-R2-C2-M2-A3-N2-T3-E2-H3 genotype constellation. The virus was phylogenetically related to feline G3P[9] strains and other human G6P[9] rotaviruses of presumable zoonotic origin. Analysis of primer binding sites of G6 specific genotyping revealed further evidence of a G6P[9] feline reservoir. Moreover, substantial deficits of conventional semi-nested PCR genotyping approaches in detecting contemporary G6P[9] were revealed. Rotavirus strain GER29-14 most likely resulted from a direct or recent interspecies transmission from a cat to human. Further studies could assess nucleic acid sequences and genotype constellations of feline rotavirus to confirm the likely feline origin of sporadic human G6P[9] strains. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. 78 FR 26249 - Drawbridge Operation Regulation; Lake Washington Ship Canal, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-06

    ...The Coast Guard has issued a temporary deviation from the operating schedule that governs the Montlake Bridge across the Lake Washington Ship Canal, mile 5.2, at Seattle, WA, and the University Bridge across the Lake Washington Ship Canal, mile 4.3, at Seattle, WA. This deviation is necessary to accommodate the ``Beat the Bridge'' foot race. This deviation allows the bridges to remain in the closed position to allow safe movement of event participants.

  17. NASA Project Constellation Systems Engineering Approach

    NASA Technical Reports Server (NTRS)

    Dumbacher, Daniel L.

    2005-01-01

    NASA's Office of Exploration Systems (OExS) is organized to empower the Vision for Space Exploration with transportation systems that result in achievable, affordable, and sustainable human and robotic journeys to the Moon, Mars, and beyond. In the process of delivering these capabilities, the systems engineering function is key to implementing policies, managing mission requirements, and ensuring technical integration and verification of hardware and support systems in a timely, cost-effective manner. The OExS Development Programs Division includes three main areas: (1) human and robotic technology, (2) Project Prometheus for nuclear propulsion development, and (3) Constellation Systems for space transportation systems development, including a Crew Exploration Vehicle (CEV). Constellation Systems include Earth-to-orbit, in-space, and surface transportation systems; maintenance and science instrumentation; and robotic investigators and assistants. In parallel with development of the CEV, robotic explorers will serve as trailblazers to reduce the risk and costs of future human operations on the Moon, as well as missions to other destinations, including Mars. Additional information is included in the original extended abstract.

  18. Earth Radiation Imbalance from a Constellation of 66 Iridium Satellites: Technological Aspects

    NASA Technical Reports Server (NTRS)

    Wiscombe, W.; Chiu, C. J-Y.

    2012-01-01

    Iridium Communications Inc. is launching a new generation of polar orbiting communication satellites in 2015-2017. Iridium will provide a hosted payload bay on each of the 66 satellites (plus 6 in-space spares). This offers the potential for a paradigm shift in the way we measure Earth radiation imbalance from space, as well as massive cost savings. Because the constellation provides 24/7 global coverage, there is no need to account for diurnal cycle via extrapolations from uncalibrated narrowband geostationary imagers. And the spares can be rolled over to view the Sun and deep space, then transfer their calibration to the other members of the constellation during the frequent cross-overs. In part using simulations of the constellation viewing realistic Earth scenes, this presentation will address the technological aspects of such a constellation: (1) the calibration strategy; (2) the highly-accurate and stable radiometers for measuring outgoing flux; and (3) the GRACE-inspired algorithms for representing the outgoing flux field in spherical harmonics and thus achieving rv500-km spatial resolution and two-hour temporal resolution.

  19. 76 FR 73664 - Notice of Inventory Completion: Washington State University, Museum of Anthropology, Pullman, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ...: Washington State University, Museum of Anthropology, Pullman, WA AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Washington State University, Museum of Anthropology (WSU) has completed an... University, Museum of Anthropology, Pullman, WA 99164-4910, telephone (509) 335-4314. SUPPLEMENTARY...

  20. 75 FR 14463 - Notice of Inventory Completion: University of Washington, Department of Anthropology, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-25

    ... Washington, Department of Anthropology, Seattle, WA AGENCY: National Park Service, Interior. ACTION: Notice... University of Washington, Department of Anthropology, Seattle, WA. The human remains were removed from... University of Washington, Department of Anthropology and Burke Museum staff in consultation with...

  1. Science with Constellation-X, Choice of Instrumentation

    NASA Technical Reports Server (NTRS)

    Hornscheimeier, Ann; White, Nicholas; Tananbaum, Harvey; Garcia, Michael; Bookbinder, Jay; Petre, Robert; Cottam, Jean

    2007-01-01

    The Constellation X-ray Observatory is one of the two Beyond Einstein Great Observatories and will provide a 100-fold increase in collecting area in high spectral resolving power X-ray instruments over the Chandra and XMM-Newton gratings instruments. The mission has four main science objectives which drive the requirements for the mission. This contribution to the Garmire celebration conference describes these four science areas: Black Holes, Dark Energy, Missing Baryons, and the Neutron Star Equation of State as well as the requirements flow-down that give rise to the choice of instrumentation and implementation for Constellation-X. As we show, each of these science areas place complementary constraints on mission performance parameters such as collecting area, spectral resolving power, timing resolution, and field of view. The mission's capabilities will enable a great breadth of science, and its resources will be open to the community through its General Observer program.

  2. International Earth Science Constellation (ESC) Introduction

    NASA Technical Reports Server (NTRS)

    Guit, William J.; Machado, Michael J.

    2016-01-01

    This is the Welcome and Introduction presentation for the International Earth Science Constellation (ESC) Mission Operations Working Group (MOWG) meeting held in Albuquerque NM from September 27-29. It contains an org chart, charter, history, significant topics to be discussed, AquaAura 2017 inclination adjust maneuver calendar, a-train long range plans, upcoming events, and action items.

  3. End-to-End Trade-Space Analysis for Designing Constellation

    NASA Technical Reports Server (NTRS)

    Le Moigne, Jacqueline; Dabney, Philip; Foreman, Veronica; Grogan, Paul T.; Hache, Sigfried; Holland, Matthew; Hughes, Steven; Nag, Sreeja; Siddiqi, Afreen

    2017-01-01

    Multipoint measurement missions can provide a significant advancement in science return and this science interest coupled with as many recent technological advances are driving a growing trend in exploring distributed architectures for future NASA missions. Distributed Spacecraft Missions (DSMs) leverage multiple spacecraft to achieve one or more common goals. In particular, a constellation is the most general form of DSM with two or more spacecraft placed into specific orbit(s) for the purpose of serving a common objective (e.g., CYGNSS). Because a DSM architectural trade-space includes both monolithic and distributed design variables, DSM optimization is a large and complex problem with multiple conflicting objectives. Over the last two years, our team has been developing a Trade-space Analysis Tool for Constellations (TAT-C), implemented in common programming languages for pre-Phase A constellation mission analysis. By evaluating alternative mission architectures, TAT-C seeks to minimize cost and maximize performance for pre-defined science goals. This presentation will describe the overall architecture of TAT-C including: a User Interface (UI) at several levels of details and user expertise; Trade-space Search Requests that are created from the Science requirements gathered by the UI and validated by a Knowledge Base; a Knowledge Base to compare the current requests to prior mission concepts to potentially prune the trade-space; a Trade-space Search Iterator which, with inputs from the Knowledge Base, and, in collaboration with the Orbit & Coverage, Reduction & Metrics, and Cost& Risk modules, generates multiple potential architectures and their associated characteristics. TAT-C leverages the use of the Goddard Mission Analysis Tool (GMAT) to compute coverage and ancillary data, modeling orbits to balance accuracy and performance. The current version includes uniform and non-uniform Walker constellations as well as Ad-Hoc and precessing constellations, and its

  4. Defining the Natural Atmospheric Environment Requirements for the NASA Constellation Program

    NASA Technical Reports Server (NTRS)

    Roberts, Barry C.; Leahy, Frank

    2008-01-01

    The National Aeronautics and Space Administration began developing a new vehicle under the Constellation Program to replace the Space Shuttle. The Ares-1 launch vehicle and the Orion capsule will be used to ferry crew and some payloads to the International Space Station and will also be used for new missions to the moon, As development of this new vehicle begins, the Natural Environments Branch at Marshall Space Flight Center has been tasked with defining the natural environments the vehicle will encounter and working with the program to develop natural environmental requirements for the vehicles' elements. An overview of the structure of the program is given, along with a description of the Constellation Design Specification for Natural Environments and the Constellation Natural Environments Definition for Design documents and how they apply to the Ares-I and Orion vehicles.

  5. A walk through the heavens : a guide to stars and constellations and their legends

    NASA Astrophysics Data System (ADS)

    Heifetz, Milton D.; Tirion, Wil

    What star is that? Where's the Great Bear? Who was Andromeda? A Walk through the Heavens is your guide to the pathways of the night sky, answering the commonest questions about what you can see up there. There are simplified maps of the constellations, together with instructions on how to gauge their sizes and the distances between them. With this information you can find the constellations easily, and make a journey by eye from one constellation to the next. Ancient myths surrounding the constellations are retold, enriching our understanding of how historical peoples saw the awe-inspiring spectacle of a sky sprinkled with stars. This book, magically illustrated by Wil Tirion, does not require any instrument or telescope. It is an ideal introduction to launch a young astronomer on a journey across starlit skies.

  6. Kilohoku Ho`okele Wa`a : Astronomy of the Modern Hawaiian Wayfinders

    NASA Astrophysics Data System (ADS)

    Ha`o, Celeste; Dye, Ahia G.; Slater, Stephanie J.; Slater, Timothy F.; Baybayan, Kalepa

    2015-08-01

    This paper provides an introduction to Kilohoku Ho`okele Wa`a, the astronomy of the Hawaiian wayfinders. Rooted in a legacy of navigation across the Polynesian triangle, wayfinding astronomy has been part of a suite of skills that allows navigators to deliberately hop between the small islands of the Pacific, for thousands of years. Forty years ago, in one manifestation of the Hawaiian Renaissance, our teachers demonstrated that ancient Hawaiians were capable of traversing the wide Pacific to settle and trade on islands separated by thousands of miles. Today those same mentors train a new generation of navigators, making Hawaiian voyaging a living, evolving, sustainable endeavor. This paper presents two components of astronomical knowledge that all crewmen, but particularly those in training to become navigators, learn early in their training. Na Ohana Hoku, the Hawaiian Star Families constitute the basic units of the Hawaiian sky. In contrast to the Western system of 88 constellations, Na Ohana Hoku divides the sky into four sections that each run from the northern to the southern poles. This configuration reduces cognitive load, allowing the navigator to preserve working memory for other complex tasks. In addition, these configurations of stars support the navigator in finding and generatively using hundreds of individual, and navigationally important pairs of stars. The Hawaiian Star Compass divides the celestial sphere into a directional system that uses 32 rather than 8 cardinal points. Within the tropics, the rising and setting of celestial objects are consistent within the Hawaiian Star Compass, providing for extremely reliable direction finding. Together, Na Ohana Hoku and the Hawaiian Star Compass provide the tropical navigator with astronomical assistance that is not available to, and would have been unknown to Western navigators trained at higher latitudes.

  7. Science Opportunities Enabled by NASA's Constellation System: Interim Report

    NASA Technical Reports Server (NTRS)

    2008-01-01

    In 2004 NASA initiated studies of advanced science mission concepts known as the Vision Missions and inspired by a series of NASA roadmap activities conducted in 2003. Also in 2004 NASA began implementation of the first phases of a new space exploration policy, the Vision for Space Exploration. This implementation effort included development of a new human-carrying spacecraft, known as Orion, and two new launch vehicles, the Ares I and Ares V rockets.collectively called the Constellation System. NASA asked the National Research Council (NRC) to evaluate the science opportunities enabled by the Constellation System (see Preface) and to produce an interim report on a short time schedule and a final report by November 2008. The committee notes, however, that the Constellation System and its Orion and Ares vehicles have been justified by NASA and selected in order to enable human exploration beyond low Earth orbit, and not to enable science missions. This interim report of the Committee on Science Opportunities Enabled by NASA s Constellation System evaluates the 11 Vision Mission studies presented to it and groups them into two categories: those more deserving of future study, and those less deserving of future study. Although its statement of task also refers to Earth science missions, the committee points out that the Vision Missions effort was focused on future astronomy, heliophysics, and planetary exploration and did not include any Earth science studies because, at the time, the NRC was conducting the first Earth science decadal survey, and funding Earth science studies as part of the Vision Missions effort would have interfered with that process. Consequently, no Earth science missions are evaluated in this interim report. However, the committee will evaluate any Earth science mission proposal submitted in response to its request for information issued in March 2008 (see Appendix A). The committee based its evaluation of the preexisting Vision Missions studies

  8. 75 FR 23589 - Safety Zone Regulations, Seafair Blue Angels Air Show Performance, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ... Zone Regulations, Seafair Blue Angels Air Show Performance, Seattle, WA AGENCY: Coast Guard, DHS... Washington, WA for the annual Seafair Blue Angels Air Show from 10 a.m. on August 5, 2010 to 6 p.m. on August... Washington for the annual Seafair Blue Angels Air Show Performance. The Coast Guard will enforce the safety...

  9. Precise orbit determination of Multi-GNSS constellation including GPS GLONASS BDS and GALIEO

    NASA Astrophysics Data System (ADS)

    Dai, Xiaolei

    2014-05-01

    In addition to the existing American global positioning system (GPS) and the Russian global navigation satellite system (GLONASS), the new generation of GNSS is emerging and developing, such as the Chinese BeiDou satellite navigation system (BDS) and the European GALILEO system. Multi-constellation is expected to contribute to more accurate and reliable positioning and navigation service. However, the application of multi-constellation challenges the traditional precise orbit determination (POD) strategy that was designed usually for single constellation. In this contribution, we exploit a more rigorous multi-constellation POD strategy for the ongoing IGS multi-GNSS experiment (MGEX) where the common parameters are identical for each system, and the frequency- and system-specified parameters are employed to account for the inter-frequency and inter-system biases. Since the authorized BDS attitude model is not yet released, different BDS attitude model are implemented and their impact on orbit accuracy are studied. The proposed POD strategy was implemented in the PANDA (Position and Navigation Data Analyst) software and can process observations from GPS, GLONASS, BDS and GALILEO together. The strategy is evaluated with the multi-constellation observations from about 90 MGEX stations and BDS observations from the BeiDou experimental tracking network (BETN) of Wuhan University (WHU). Of all the MGEX stations, 28 stations record BDS observation, and about 80 stations record GALILEO observations. All these data were processed together in our software, resulting in the multi-constellation POD solutions. We assessed the orbit accuracy for GPS and GLONASS by comparing our solutions with the IGS final orbit, and for BDS and GALILEO by overlapping our daily orbit solution. The stability of inter-frequency bias of GLONASS and inter-system biases w.r.t. GPS for GLONASS, BDS and GALILEO were investigated. At last, we carried out precise point positioning (PPP) using the multi-constellation

  10. Trade-Space Analysis Tool for Constellations (TAT-C)

    NASA Technical Reports Server (NTRS)

    Le Moigne, Jacqueline; Dabney, Philip; de Weck, Olivier; Foreman, Veronica; Grogan, Paul; Holland, Matthew; Hughes, Steven; Nag, Sreeja

    2016-01-01

    Traditionally, space missions have relied on relatively large and monolithic satellites, but in the past few years, under a changing technological and economic environment, including instrument and spacecraft miniaturization, scalable launchers, secondary launches as well as hosted payloads, there is growing interest in implementing future NASA missions as Distributed Spacecraft Missions (DSM). The objective of our project is to provide a framework that facilitates DSM Pre-Phase A investigations and optimizes DSM designs with respect to a-priori Science goals. In this first version of our Trade-space Analysis Tool for Constellations (TAT-C), we are investigating questions such as: How many spacecraft should be included in the constellation? Which design has the best costrisk value? The main goals of TAT-C are to: Handle multiple spacecraft sharing a mission objective, from SmallSats up through flagships, Explore the variables trade space for pre-defined science, cost and risk goals, and pre-defined metrics Optimize cost and performance across multiple instruments and platforms vs. one at a time.This paper describes the overall architecture of TAT-C including: a User Interface (UI) interacting with multiple users - scientists, missions designers or program managers; an Executive Driver gathering requirements from UI, then formulating Trade-space Search Requests for the Trade-space Search Iterator first with inputs from the Knowledge Base, then, in collaboration with the Orbit Coverage, Reduction Metrics, and Cost Risk modules, generating multiple potential architectures and their associated characteristics. TAT-C leverages the use of the Goddard Mission Analysis Tool (GMAT) to compute coverage and ancillary data, streamlining the computations by modeling orbits in a way that balances accuracy and performance.TAT-C current version includes uniform Walker constellations as well as Ad-Hoc constellations, and its cost model represents an aggregate model consisting of

  11. Operationalizing the Joint Information Environment: Achieving Information Dominance with the Undersea Constellation

    DTIC Science & Technology

    2014-11-01

    Approved for public release. OPERATIONALIZING THE JOINT INFORMATION ENVIRONMENT: ACHIEVING INFORMATION DOMINANCE WITH THE UNDERSEA CONSTELLATION* Captain...SUBTITLE Operationalizing the Joint Information Environment: Achieving Information Dominance with the Undersea Constellation (U) 5a. CONTRACT NUMBER...predict what is over the horizon, faster than the adversary. As noted in the U.S. Navy’s Vision for Information Dominance , “The Navy will create a

  12. Enterovirus genotypes among patients with severe acute respiratory illness, influenza-like illness, and asymptomatic individuals in South Africa, 2012-2014.

    PubMed

    Hellferscee, Orienka; Tempia, Stefano; Walaza, Sibongile; Variava, Ebrahim; Dawood, Halima; Wolter, Nicole; Madhi, Shabir A; du Plessis, Mignon; Cohen, Cheryl; Treurnicht, Florette K

    2017-10-01

    Enteroviruses can cause outbreaks of severe acute respiratory illness (SARI) and EV-A, -B, -C, and -D species have different pathogenic profiles and circulation patterns. We aimed to characterize and determine the prevalence of enterovirus genotypes among South African patients with respiratory illness and controls during June 2012 to July 2014. Syndromic SARI and influenza-like illness (ILI) surveillance was performed at two sentinel sites. At each site nasopharyngeal/oropharyngeal specimens were collected from SARI and ILI patients as well as controls. Specimens were tested for enterovirus by real-time PCR. Positive specimens were further genotyped by sequencing a region of the VP1 gene. The prevalence of enterovirus was 5.8% (87/1494), 3.4% (103/3079), and 3.4% (46/1367) among SARI, ILI, and controls, respectively (SARI/controls, P = 0.002 and ILI/control, P = 0.973). Among the 101/236 (42.8%) enterovirus-positive specimens that could be genotyped, we observed a high diversity of circulating enterovirus genotypes (a total of 33 genotypes) from all four human enterovirus species with high prevalence of Enterovirus-B (60.4%; 61/101) and Enterovirus-A (21.8%; 22/101) compared to Enterovirus-C (10.9%; 11/101) and Enterovirus-D (6.9%; 7/101) (P = 0.477). Of the enterovirus genotypes identified, Echovirus 30 (9.9%, 10/101), Coxsackie virus B5 (7.9%, 8/101) and Enterovirus-D68 (6.9%, 7/101) were most prevalent. There was no difference in disease severity (SARI or ILI compared to controls) between the different enterovirus species (P = 0.167). We observed a high number of enterovirus genotypes in patients with respiratory illness and in controls from South Africa with no disease association of EV species with disease severity. © 2017 Wiley Periodicals, Inc.

  13. Optimal signal constellation design for ultra-high-speed optical transport in the presence of nonlinear phase noise.

    PubMed

    Liu, Tao; Djordjevic, Ivan B

    2014-12-29

    In this paper, we first describe an optimal signal constellation design algorithm suitable for the coherent optical channels dominated by the linear phase noise. Then, we modify this algorithm to be suitable for the nonlinear phase noise dominated channels. In optimization procedure, the proposed algorithm uses the cumulative log-likelihood function instead of the Euclidian distance. Further, an LDPC coded modulation scheme is proposed to be used in combination with signal constellations obtained by proposed algorithm. Monte Carlo simulations indicate that the LDPC-coded modulation schemes employing the new constellation sets, obtained by our new signal constellation design algorithm, outperform corresponding QAM constellations significantly in terms of transmission distance and have better nonlinearity tolerance.

  14. Relationships between Social Cognition and Sibling Constellations.

    ERIC Educational Resources Information Center

    Goebel, Barbara L.

    1985-01-01

    First and second born college students (N=178) responded to measures of four social cognition factors. Multivariate analysis of variance identified relationships of social cognition factors with five sibling constellation components: subject's sex, subject's birth order (first or second), adjacent first or second born sibling's sex, spacing…

  15. 76 FR 34867 - Safety Zone Regulations, Seafair Blue Angels Air Show Performance, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-15

    ... Zone Regulations, Seafair Blue Angels Air Show Performance, Seattle, WA AGENCY: Coast Guard, DHS... Blue Angels Air Show safety zone on Lake Washington, Seattle, WA from 9 a.m. on August 4, 2011 to 4 p.m... Seafair Blue Angels Air Show Performance safety zone in 33 CFR 165.1319 daily from 9 a.m. until 4 p.m...

  16. Molecular detection and genotyping of enteroviruses from CSF samples of patients with suspected sepsis-like illness and/or aseptic meningitis from 2012 to 2015 in West Bank, Palestine.

    PubMed

    Dumaidi, Kamal; Al-Jawabreh, Amer

    2017-01-01

    Human enteroviruses (HEVs) are the most frequently reported cause of aseptic meningitis with or without CSF pleocytosis in childhood. Rapid detection and genotype of HEVs is essential to determine the causative agent and variant causing sepsis-like illness and/or aseptic meningitis. To investigate the molecular epidemiology of enteroviruses (EVs) among patients with sepsis-like illness and/or aseptic meningitis admitted to three major hospitals in West Bank, Palestine from 2012 to 2015. During the study period, 356 CSF samples were collected from patients with sepsis-like illness and/or aseptic meningitis. Two RT-nested PCR assays targeting a partial part of 5'UTR for direct diagnosis and the VP1 region for genotyping by sequence analysis of the viral genome were used. HEV RNA was detected in 66 of 356 (18.5%) of CSF samples. Age distribution showed that 64% (42/66) were infants (<1 year), 18% were children between 1 and 5 years old, 12% were children between 5 and 10 years old, and 6% were more than 10 years old. Of the 66 EV cases, 12 were successfully genotyped. Five different EV genotypes were identified. All of them belonged to HEV-B species. The study showed that echovirus 6 genotype accounted for 42% of the sequenced cases. The HEV infections in the present study tended to show slight seasonal pattern with more cases occurring during spring and summer, yet still significant numbers were also reported in fall and winter seasons. HEV was isolated from a significant number of children with sepsis-like illness and/or aseptic meningitis. In addition, the molecular method utilized for direct diagnosis and genotyping of HEV from CSF revealed that more than one HEV type circulated in the West Bank, Palestine during the study period.

  17. Molecular detection and genotyping of enteroviruses from CSF samples of patients with suspected sepsis-like illness and/or aseptic meningitis from 2012 to 2015 in West Bank, Palestine

    PubMed Central

    Dumaidi, Kamal; Al-Jawabreh, Amer

    2017-01-01

    Background Human enteroviruses (HEVs) are the most frequently reported cause of aseptic meningitis with or without CSF pleocytosis in childhood. Rapid detection and genotype of HEVs is essential to determine the causative agent and variant causing sepsis-like illness and/or aseptic meningitis. Aim To investigate the molecular epidemiology of enteroviruses (EVs) among patients with sepsis-like illness and/or aseptic meningitis admitted to three major hospitals in West Bank, Palestine from 2012 to 2015. Methods During the study period, 356 CSF samples were collected from patients with sepsis-like illness and/or aseptic meningitis. Two RT-nested PCR assays targeting a partial part of 5'UTR for direct diagnosis and the VP1 region for genotyping by sequence analysis of the viral genome were used. Results HEV RNA was detected in 66 of 356 (18.5%) of CSF samples. Age distribution showed that 64% (42/66) were infants (<1 year), 18% were children between 1 and 5 years old, 12% were children between 5 and 10 years old, and 6% were more than 10 years old. Of the 66 EV cases, 12 were successfully genotyped. Five different EV genotypes were identified. All of them belonged to HEV-B species. The study showed that echovirus 6 genotype accounted for 42% of the sequenced cases. The HEV infections in the present study tended to show slight seasonal pattern with more cases occurring during spring and summer, yet still significant numbers were also reported in fall and winter seasons. Conclusion HEV was isolated from a significant number of children with sepsis-like illness and/or aseptic meningitis. In addition, the molecular method utilized for direct diagnosis and genotyping of HEV from CSF revealed that more than one HEV type circulated in the West Bank, Palestine during the study period. PMID:28225788

  18. 75 FR 71638 - Safety Zone; Fleet Week Maritime Festival, Pier 66, Elliot Bay, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ...-AA00 Safety Zone; Fleet Week Maritime Festival, Pier 66, Elliot Bay, Seattle, WA AGENCY: Coast Guard...) entitled ``Safety Zone; Fleet Week Maritime Festival, Pier 66, Elliot Bay, Seattle, WA'' (Docket number...; Fleet Week Maritime Festival, Pier 66, Elliott Bay, Seattle, Washington. (a) Location. The following...

  19. Similar view to WA1832; Historic view just west of powerhouse ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Similar view to WA-18-32; Historic view just west of powerhouse during reconstruction of penstocks and replacement of original Francis Turbine with pelton wheels, in 1912; Derrick used to lift construction materials in center, the stairway to the right leads to the transformer house, the gable-roof building to the right is a workshop (built CA 1904), whitewashed building to the left is the company hotel (built CA. 1904, and the gable-roof building in the distance is a barn (built CA. 1904). (photographer unknown, ca 1912.) - Nooksack Falls Hydroelectric Plant, Route 542, Glacier, Whatcom County, WA

  20. Management of the Reflection Grating Spectrometer on the Constellation-X Mission

    NASA Technical Reports Server (NTRS)

    2004-01-01

    As RGS Integrated Product Team Lead, normal coordination and management efforts in the past year have involved setting and overseeing budgets and schedules, regular status reporting to the Program Manager at Goddard Space Flight Center (GSFC), interacting with Constellation-X groups at GSFC, Smithsonian Astrophysical Observatory (SAO), and RGS team institutions, and supporting the program needs of Constellation-X. In addition to the management aspects described above, there are four significant areas of direct contribution that were accomplished.

  1. Micro-satellite constellations for monitoring cryospheric processes and related natural hazards

    NASA Astrophysics Data System (ADS)

    Kaeaeb, A.; Altena, B.; Mascaro, J.

    2016-12-01

    Currently, several micro-satellite constellations for earth-observation are planned or under build-up. Here, we assess the potential of the well-advanced Planet satellite constellation for investigating cryospheric processes. In its final stage, the Planet constellation will consist of 150 free-flying micro-satellites in near-polar and ISS orbits. The instruments carry RGB+NIR frame cameras that image the Earth surface in nadir direction with resolutions of 3-5 m, covering 20 x 13 km per image. In its final set-up, the constellation will be able to image the (almost) entire land surface at least once per day, under the limitation of cloud cover. Here, we explore new possibilities for insight into cryospheric processes that this very high repeat cycle combined with high image resolution offer. Based on repeat Planet imagery we derive repeat glacier velocity fields for example glaciers in the northern and southern hemispheres. We find it especially useful to monitor the ice velocities near calving fronts and simultaneously detect changes of the front, pointing to calving events. We also explore deformation fields over creeping mountain permafrost, so-called rockglaciers. As a second, very promising cryospheric application we suggest monitoring of glacier and permafrost related natural hazards. In cases such as temporary lakes, lake outbursts, landslides, rock avalanches, visual information over remote areas and at high frequencies are crucial for hazard assessment, early warning or disaster management. Based on several examples, we demonstrate that massive micro-satellite constellations such Planet's are exactly able to provide this type of information. As a third promising example, we show how such high-repeat optical satellite data are useful to monitor river ice and related jams and flooding. At certain latitudes, the repeat frequency of the data is even high enough to track river ice floes and thus water velocities.

  2. Fluxgate Magnetometry on the Experimental Albertan Satellite #1 (Ex-Alta-1) CubeSat Mission: Steps Toward a Magnetospheric Constellation Mission

    NASA Astrophysics Data System (ADS)

    Mann, I. R.; Miles, D.; Nokes, C.; Cupido, C.; Elliott, D.; Ciurzynski, M.; Barona, D.; Narod, B. B.; Bennest, J.; Pakhotin, I.; Kale, A.; Bruner, B.; Haluza-DeLay, T.; Forsyth, C.; Rae, J.; Lange, C.; Sameoto, D.; Milling, D. K.

    2017-12-01

    Making low noise magnetic measurements is a significant challenge to the use of cube-satellite (CubeSat) platforms for scientific constellation class missions for studies of geospace. We describe the design, validation, and test, and initial on-orbit results from a miniature, low-mass, low-power, and low-magnetic noise boom-mounted fluxgate magnetometer flown on the University of Alberta Experimental Albertan Satellite #1 (Ex-Alta-1) Cube Satellite, launched in 2017 from the International Space Station as part of the QB50 constellation mission. The miniature instrument achieves a magnetic noise floor of 150-200 pT/√Hz at 1 Hz, consumes 400 mW of power, has a mass of 121 g (sensor and boom), stows on the hull, and deploys on a 60 cm boom from a three-unit CubeSat reducing the noise from the onboard reaction wheel to less than 1.5 nT at the sensor. The instrument's capabilities are being demonstrated and validated in space with flight on Ex-Alta-1. We present on-orbit data from the boom-deployment and initial operations of the fluxgate sensor and illustrate the potential scientific returns and utility of using CubeSats carrying such fluxgate magnetometers to constitute a magnetospheric constellation mission. We further illustrate the value of scientific constellations using example data from the low-Earth orbit European Space Agency Swarm mission. Swarm data reveal significant changes in the spatiotemporal characteristics of the magnetic fields in the coupled magnetosphere-ionosphere system, even when the spacecraft are separated by only approximately 10 s along track and approximately 1.4° in longitude. This indicates the likely energetic significance of Alfven wave dynamics, and we use Swarm measurements to illustrate the value of satellite constellations for diagnosing magnetosphere-ionosphere coupling even in low-Earth orbit.

  3. The NASA CYGNSS Small Satellite Constellation

    NASA Astrophysics Data System (ADS)

    Ruf, C. S.; Gleason, S.; McKague, D. S.; Rose, R.; Scherrer, J.

    2017-12-01

    The NASA Cyclone Global Navigation Satellite System (CYGNSS) is a constellation of eight microsatellite observatories that was launched into a low (35°) inclination, low Earth orbit on 15 December 2016. Each observatory carries a 4-channel GNSS-R bistatic radar receiver. The radars are tuned to receive the L1 signals transmitted by GPS satellites, from which near-surface ocean wind speed is estimated. The mission architecture is designed to improve the temporal sampling of winds in tropical cyclones (TCs). The 32 receive channels of the complete CYGNSS constellation, combined with the 30 GPS satellite transmitters, results in a revisit time for sampling of the wind of 2.8 hours (median) and 7.2 hours (mean) at all locations between 38 deg North and 38 deg South latitude. Operation at the GPS L1 frequency of 1575 MHz allows for wind measurements in the TC inner core that are often obscured from other spaceborne remote sensing instruments by intense precipitation in the eye wall and inner rain bands. An overview of the CYGNSS mission wil be presented, followed by early on-orbit status and results.

  4. Constellation crew exploration vehicle, or CEV, is being prepare

    NASA Image and Video Library

    2007-11-27

    In Hangar N at NASA's Kennedy Space Center, a heat shield for the Constellation crew exploration vehicle, or CEV, is being prepared for a demonstration. A developmental heat shield for the Orion spacecraft is being tested and evaluated at Kennedy. The shield was designed and assembled by the Boeing Company in Huntington Beach, Calif., for NASA's Constellation Program. The thermal protection system manufacturing demonstration unit is designed to protect astronauts from extreme heat during re-entry to Earth's atmosphere from low Earth orbit and lunar missions. The CEV will be used to dock and gain access to the International Space Station, travel to the moon in the 2018 timeframe and play a crucial role in exploring Mars.

  5. Toward quantum-like modeling of financial processes

    NASA Astrophysics Data System (ADS)

    Choustova, Olga

    2007-05-01

    We apply methods of quantum mechanics for mathematical modeling of price dynamics at the financial market. We propose to describe behavioral financial factors (e.g., expectations of traders) by using the pilot wave (Bohmian) model of quantum mechanics. Trajectories of prices are determined by two financial potentials: classical-like V(q) ("hard" market conditions, e.g., natural resources) and quantum-like U(q) (behavioral market conditions). On the one hand, our Bohmian model is a quantum-like model for the financial market, cf. with works of W. Segal, I. E. Segal, E. Haven, E. W. Piotrowski, J. Sladkowski. On the other hand, (since Bohmian mechanics provides the possibility to describe individual price trajectories) it belongs to the domain of extended research on deterministic dynamics for financial assets (C.W.J. Granger, W.A. Barnett, A. J. Benhabib, W.A. Brock, C. Sayers, J. Y. Campbell, A. W. Lo, A. C. MacKinlay, A. Serletis, S. Kuchta, M. Frank, R. Gencay, T. Stengos, M. J. Hinich, D. Patterson, D. A. Hsieh, D. T. Caplan, J.A. Scheinkman, B. LeBaron and many others).

  6. A unique constellation of spacecraft constellations to study Kelvin-Helmholtz Instability in 2017-2020: MMS, Cluster and Themis

    NASA Astrophysics Data System (ADS)

    Masson, A.; Nykyri, K.

    2017-12-01

    The Cluster and the Themis missions have shed a total new light on the Kelvin-Helmholtz Instability (KHI) mechanism at the magnetopause. To name a few, these missions have enabled the observation of KHI rolled-up vortices, for the first time with four spacecraft (Hasegawa et al., 2004). They revealed its presence under any Interplanetary Magnetic Field (IMF) conditions (Hwang et al., 2011, 2012). They also revealed that their occurence may have been largely underestimated (Kavosi and Raeder, 2015). Very recently, the presence of ion magnetosonic waves with sufficient energy to account for the observed level of ion heating within a KHI vortex may be the first evidence of cross-scale energy transport (Moore et al., 2016). After presenting some the main highlights of Cluster and Themis on this phenomenon, we will present upcoming new observations with MMS, Cluster and Themis in 2017-2020 timeframe. Together, they will form a unique constellation of spacecraft constellations to study this phenomenon for the first time. We will present some of the key scientific questions these new data will enable to tackle.

  7. Error Reduction Analysis and Optimization of Varying GRACE-Type Micro-Satellite Constellations

    NASA Astrophysics Data System (ADS)

    Widner, M. V., IV; Bettadpur, S. V.; Wang, F.; Yunck, T. P.

    2017-12-01

    The Gravity Recovery and Climate Experiment (GRACE) mission has been a principal contributor in the study and quantification of Earth's time-varying gravity field. Both GRACE and its successor, GRACE Follow-On, are limited by their paired satellite design which only provide a full map of Earth's gravity field approximately every thirty days and at large spatial resolutions of over 300 km. Micro-satellite technology has presented the feasibility of improving the architecture of future missions to address these issues with the implementation of a constellations of satellites having similar characteristics as GRACE. To optimize the constellation's architecture, several scenarios are evaluated to determine how implementing this configuration affects the resultant gravity field maps and characterize which instrument system errors improve, which do not, and how changes in constellation architecture affect these errors.

  8. 76 FR 9051 - Notice of Inventory Completion: Washington State Department of Natural Resources, Olympia, WA and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-16

    ... Anthropology, Seattle, WA; Correction AGENCY: National Park Service, Interior. ACTION: Notice; correction... of Washington, Department of Anthropology, Seattle, WA. The human remains were removed from... Notice, the University of Washington, Department of Anthropology, had believed it was in control of the...

  9. 76 FR 30014 - Safety Zone; Fleet Week Maritime Festival, Pier 66, Elliott Bay, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ...-AA00 Safety Zone; Fleet Week Maritime Festival, Pier 66, Elliott Bay, Seattle, WA AGENCY: Coast Guard...) entitled ``Safety Zone; Fleet Week Maritime Festival, Pier 66, Elliott Bay, Seattle, WA'' in the Federal... is added to read as follows: Sec. 165.1330 Safety Zone; Fleet Week Maritime Festival, Pier 66...

  10. Scheduling algorithms for rapid imaging using agile Cubesat constellations

    NASA Astrophysics Data System (ADS)

    Nag, Sreeja; Li, Alan S.; Merrick, James H.

    2018-02-01

    Distributed Space Missions such as formation flight and constellations, are being recognized as important Earth Observation solutions to increase measurement samples over space and time. Cubesats are increasing in size (27U, ∼40 kg in development) with increasing capabilities to host imager payloads. Given the precise attitude control systems emerging in the commercial market, Cubesats now have the ability to slew and capture images within short notice. We propose a modular framework that combines orbital mechanics, attitude control and scheduling optimization to plan the time-varying, full-body orientation of agile Cubesats in a constellation such that they maximize the number of observed images and observation time, within the constraints of Cubesat hardware specifications. The attitude control strategy combines bang-bang and PD control, with constraints such as power consumption, response time, and stability factored into the optimality computations and a possible extension to PID control to account for disturbances. Schedule optimization is performed using dynamic programming with two levels of heuristics, verified and improved upon using mixed integer linear programming. The automated scheduler is expected to run on ground station resources and the resultant schedules uplinked to the satellites for execution, however it can be adapted for onboard scheduling, contingent on Cubesat hardware and software upgrades. The framework is generalizable over small steerable spacecraft, sensor specifications, imaging objectives and regions of interest, and is demonstrated using multiple 20 kg satellites in Low Earth Orbit for two case studies - rapid imaging of Landsat's land and coastal images and extended imaging of global, warm water coral reefs. The proposed algorithm captures up to 161% more Landsat images than nadir-pointing sensors with the same field of view, on a 2-satellite constellation over a 12-h simulation. Integer programming was able to verify that

  11. Autonomy Architectures for a Constellation of Spacecraft

    NASA Technical Reports Server (NTRS)

    Barrett, Anthony

    2000-01-01

    Until the past few years, missions typically involved fairly large expensive spacecraft. Such missions have primarily favored using older proven technologies over more recently developed ones, and humans controlled spacecraft by manually generating detailed command sequences with low-level tools and then transmitting the sequences for subsequent execution on a spacecraft controller. This approach toward controlling a spacecraft has worked spectacularly on previous missions, but it has limitations deriving from communications restrictions - scheduling time to communicate with a particular spacecraft involves competing with other projects due to the limited number of deep space network antennae. This implies that a spacecraft can spend a long time just waiting whenever a command sequence fails. This is one reason why the New Millennium program has an objective to migrate parts of mission control tasks onboard a spacecraft to reduce wait time by making spacecraft more robust. The migrated software is called a "remote agent" and has 4 components: a mission manager to generate the high level goals, a planner/scheduler to turn goals into activities while reasoning about future expected situations, an executive/diagnostics engine to initiate and maintain activities while interpreting sensed events by reasoning about past and present situations, and a conventional real-time subsystem to interface with the spacecraft to implement an activity's primitive actions. In addition to needing remote planning and execution for isolated spacecraft, a trend toward multiple-spacecraft missions points to the need for remote distributed planning and execution. The past few years have seen missions with growing numbers of probes. Pathfinder has its rover (Sojourner), Cassini has its lander (Huygens), and the New Millenium Deep Space 3 (DS3) proposal involves a constellation of 3 spacecraft for interferometric mapping. This trend is expected to continue to progressively larger fleets. For

  12. Analytical investigation of the dynamics of tethered constellations in Earth orbit (phase 2)

    NASA Technical Reports Server (NTRS)

    Lorenzini, E.; Arnold, D. A.; Grossi, M. D.; Gullahorn, G. E.

    1985-01-01

    The deployment maneuver of three axis vertical constellations with elastic tethers is analyzed. The deployment strategy devised previously was improved. Dampers were added to the system. Effective algorithms for damping out the fundamental vibrational modes of the system were implemented. Simulations of a complete deployment and a subsequent station keeping phase of a three mass constellation is shown.

  13. Does insulin-like growth factor 1 genotype influence muscle power response to strength training in older men and women?

    PubMed

    Sood, Suchi; Hanson, Erik D; Delmonico, Matthew J; Kostek, Matthew C; Hand, Brian D; Roth, Stephen M; Hurley, Ben F

    2012-02-01

    The CA-repeat polymorphism in the insulin-like growth factor 1 (IGF1) gene promoter region has been associated with strength and circulating IGF-I protein levels. The purpose of the study was to determine if the IGF1 CA-repeat polymorphism influences muscle power at baseline and in response to ST in older adults. Knee extensor peak power (PP) was measured at 50, 60, and 70% of 1-RM strength before and after 10 weeks of unilateral knee extensor ST in older adults, aged 50-85 years, to determine the changes in absolute and relative PP with ST. Subjects (N = 114) were genotyped for the IGF1 CA-repeat polymorphism and grouped as homozygous for the 192 allele, heterozygous, or non-carriers of the 192 allele. The 192 homozygotes had significantly lower baseline PP at 50, 60, and 70% of 1-RM strength than the non-carriers when age, sex, and baseline fat-free mass were covaried (all P < 0.05). This same relationship was observed when the highest PP within these ranges was compared (e.g., 317.6 ± 13.5 for 192 homozygotes and 380.2 ± 16.3 for non-carriers of the 192 allele, P < 0.05). Both absolute and relative PP increased significantly with ST in all genotype groups as expected, but there were no significant relationships among IGF1 genotypes and any of the PP changes. Despite a significant relationship between IGF1 genotype and knee extensor peak power at baseline, IGF1 genotype does not appear to influence changes in knee extensor peak power with ST.

  14. A Constellation of CubeSat InSAR Sensors for Rapid-Revisit Surface Deformation Studies

    NASA Astrophysics Data System (ADS)

    Wye, L.; Lee, S.; Yun, S. H.; Zebker, H. A.; Stock, J. D.; Wicks, C. W., Jr.; Doe, R.

    2016-12-01

    The 2007 NRC Decadal Survey for Earth Sciences highlights three major Earth surface deformation themes: 1) solid-earth hazards and dynamics; 2) human health and security; and 3) land-use change, ecosystem dynamics and biodiversity. Space-based interferometric synthetic aperture radar (InSAR) is a key change detection tool for addressing these themes. Here, we describe the mission and radar payload design for a constellation of S-band InSAR sensors specifically designed to provide the global, high temporal resolution, sub-cm level deformation accuracy needed to address some of the major Earth system goals. InSAR observations with high temporal resolution are needed to properly monitor certain nonlinearly time-varying features (e.g., unstable volcanoes, active fault lines, and heavily-used groundwater or hydrocarbon reservoirs). Good temporal coverage is also needed to reduce atmospheric artifacts by allowing multiple acquisitions to be averaged together, since each individual SAR measurement is corrupted by up to several cm of atmospheric noise. A single InSAR platform is limited in how often it can observe a given scene without sacrificing global spatial coverage. Multiple InSAR platforms provide the spatial-temporal flexibility required to maximize the science return. However, building and launching multiple InSAR platforms is cost-prohibitive for traditional satellites. SRI International (SRI) and our collaborators are working to exploit developments in nanosatellite technology, in particular the emergence of the CubeSat standard, to provide high-cadence InSAR capabilities in an affordable package. The CubeSat Imaging Radar for Earth Science (CIRES) subsystem, a prototype SAR elec­tronics package developed by SRI with support from a 2014 NASA ESTO ACT award, is specifically scaled to be a drop-in radar solution for resource-limited delivery systems like CubeSats and small airborne vehicles. Here, we present our mission concept and flow-down requirements for a

  15. Enterovirus genotypes among patients with severe acute respiratory illness, influenza-like illness, and asymptomatic individuals in South Africa, 2012–2014

    PubMed Central

    Hellferscee, Orienka; Tempia, Stefano; Walaza, Sibongile; Variava, Ebrahim; Dawood, Halima; Wolter, Nicole; Madhi, Shabir A.; du Plessis, Mignon; Cohen, Cheryl; Treurnicht, Florette K.

    2017-01-01

    Enteroviruses can cause outbreaks of severe acute respiratory illness (SARI) and EV-A, -B, -C, and -D species have different pathogenic profiles and circulation patterns. We aimed to characterize and determine the prevalence of enterovirus genotypes among South African patients with respiratory illness and controls during June 2012 to July 2014. Syndromic SARI and influenza-like illness (ILI) surveillance was performed at two sentinel sites. At each site nasopharyngeal/oropharyngeal specimens were collected from SARI and ILI patients as well as controls. Specimens were tested for enterovirus by real-time PCR. Positive specimenswere further genotyped by sequencing a region of theVP1 gene. The prevalence of enterovirus was 5.8% (87/1494), 3.4% (103/3079), and 3.4% (46/1367) among SARI, ILI, and controls, respectively (SARI/controls, P=0.002 and ILI/control, P = 0.973). Among the 101/236 (42.8%) enterovirus-positive specimens that could be genotyped, we observed a high diversity of circulating enterovirus genotypes (a total of 33 genotypes) from all four human enterovirus species with high prevalence of Enterovirus-B (60.4%; 61/101) and Enterovirus-A (21.8%; 22/101) compared to Enterovirus-C (10.9%; 11/101) and Enterovirus-D (6.9%; 7/101) (P = 0.477). Of the enterovirus genotypes identified, Echovirus 30 (9.9%, 10/101), Coxsackie virus B5 (7.9%, 8/101) and Enterovirus-D68 (6.9%, 7/101) were most prevalent. There was no difference in disease severity (SARI or ILI compared to controls) between the different enterovirus species (P = 0.167).We observed a high number of enterovirus genotypes in patients with respiratory illness and in controls from South Africa with no disease association of EV species with disease severity. PMID:28574589

  16. End-to-End Trade-space Analysis for Designing Constellation Missions

    NASA Astrophysics Data System (ADS)

    LeMoigne, J.; Dabney, P.; Foreman, V.; Grogan, P.; Hache, S.; Holland, M. P.; Hughes, S. P.; Nag, S.; Siddiqi, A.

    2017-12-01

    Multipoint measurement missions can provide a significant advancement in science return and this science interest coupled with many recent technological advances are driving a growing trend in exploring distributed architectures for future NASA missions. Distributed Spacecraft Missions (DSMs) leverage multiple spacecraft to achieve one or more common goals. In particular, a constellation is the most general form of DSM with two or more spacecraft placed into specific orbit(s) for the purpose of serving a common objective (e.g., CYGNSS). Because a DSM architectural trade-space includes both monolithic and distributed design variables, DSM optimization is a large and complex problem with multiple conflicting objectives. Over the last two years, our team has been developing a Trade-space Analysis Tool for Constellations (TAT-C), implemented in common programming languages for pre-Phase A constellation mission analysis. By evaluating alternative mission architectures, TAT-C seeks to minimize cost and maximize performance for pre-defined science goals. This presentation will describe the overall architecture of TAT-C including: a User Interface (UI) at several levels of details and user expertise; Trade-space Search Requests that are created from the Science requirements gathered by the UI and validated by a Knowledge Base; a Knowledge Base to compare the current requests to prior mission concepts to potentially prune the trade-space; a Trade-space Search Iterator which, with inputs from the Knowledge Base, and, in collaboration with the Orbit & Coverage, Reduction & Metrics, and Cost& Risk modules, generates multiple potential architectures and their associated characteristics. TAT-C leverages the use of the Goddard Mission Analysis Tool (GMAT) to compute coverage and ancillary data, modeling orbits to balance accuracy and performance. The current version includes uniform and non-uniform Walker constellations as well as Ad-Hoc and precessing constellations, and its

  17. Autonomous Scheduling Requirements for Agile Cubesat Constellations in Earth Observation

    NASA Astrophysics Data System (ADS)

    Nag, S.; Li, A. S. X.; Kumar, S.

    2017-12-01

    Distributed Space Missions such as formation flight and constellations, are being recognized as important Earth Observation solutions to increase measurement samples over space and time. Cubesats are increasing in size (27U, 40 kg) with increasing capabilities to host imager payloads. Given the precise attitude control systems emerging commercially, Cubesats now have the ability to slew and capture images within short notice. Prior literature has demonstrated a modular framework that combines orbital mechanics, attitude control and scheduling optimization to plan the time-varying orientation of agile Cubesats in a constellation such that they maximize the number of observed images, within the constraints of hardware specs. Schedule optimization is performed on the ground autonomously, using dynamic programming with two levels of heuristics, verified and improved upon using mixed integer linear programming. Our algorithm-in-the-loop simulation applied to Landsat's use case, captured up to 161% more Landsat images than nadir-pointing sensors with the same field of view, on a 2-satellite constellation over a 12-hour simulation. In this paper, we will derive the requirements for the above algorithm to run onboard small satellites such that the constellation can make time-sensitive decisions to slew and capture images autonomously, without ground support. We will apply the above autonomous algorithm to a time critical use case - monitoring of precipitation and subsequent effects on floods, landslides and soil moisture, as quantified by the NASA Unified Weather Research and Forecasting Model. Since the latency between these event occurrences is quite low, they make a strong case for autonomous decisions among satellites in a constellation. The algorithm can be implemented in the Plan Execution Interchange Language - NASA's open source technology for automation, used to operate the International Space Station and LADEE's in flight software - enabling a controller

  18. The Earth Science Afternoon Constellation: Preparing for Autonomous but Coordinated Operations

    NASA Technical Reports Server (NTRS)

    Case, Warren; Kelly, Angelita C.; Work, Kevin; Guit, William

    2005-01-01

    This paper describes how the challenges of coordinating the autonomous operations of geographically dispersed mission control centers for several small and large satellites are being overcome. The Earth Science Afternoon Constellation, also referred to as the "A-Train", is an international grouping of five NASA satellites (two major NASA EOS missions and three NASA/Earth System Science Pathfinder missions) and one French satellite orbiting in close proximity. This grouping of satellites provides scientists with the opportunity to perform coincident observations using data from two or more instruments on various satellites with measurements taken at approximately the same time. Three of the six missions are currently on-orbit, with the two missions expected to join the constellation later this year and one mission in 2007. The operational challenges are daunting for several reasons. There are several Mission Control Centers (widely separated on two continents), operating autonomously under tight budget constraints. All of the Mission Control Centers have reasons to be concerned about safety while flying in close proximity to other satellites, but most Centers did not have the resources or the desire to address this concern alone - the interfaces are too numerous and anticipated operations too costly. Clearly, an efficient approach was needed. This paper describes the steps taken to make this Earth science constellation a reality. Agreements were forged to allow the Mission Control Centers to maintain their autonomy, while ensuring their satellite's safety. Each member mission in the constellation operates independently in accordance with its own mission requirements, but the member missions have agreed to coordinate their operations, i.e., orbital positions and control to ensure the safety of the entire constellation. A centralized system was developed at NASA Goddard Space Flight Center to collect, analyze, and distribute ephemeris data used by each of the mission

  19. Distribution of hepatitis C virus genotypes in a diverse US integrated health care population.

    PubMed

    Manos, M Michele; Shvachko, Valentina A; Murphy, Rosemary C; Arduino, Jean Marie; Shire, Norah J

    2012-11-01

    Hepatitis C virus (HCV) genotypes influence response to therapy, and recently approved direct-acting antivirals are genotype-specific. Genotype distribution information can help to guide antiviral development and elucidate infection patterns. HCV genotype distributions were studied in a diverse cross-section of patients in the Northern California Kaiser Permanente health plan. Associations between genotype and race/ethnicity, age, and sex were assessed with multivariate logistic regression models. The 10,256 patients studied were median age 56 years, 62% male, 55% White non-Hispanic. Overall, 70% were genotype 1, 16% genotype 2, 12% genotype 3, 1% genotype 4, <1% genotype 5, and 1% genotype 6. Blacks (OR 4.5 [3.8-5.5]) and Asians (OR 1.2 [1.0-1.4]) were more likely to have genotype 1 than 2/3 versus non-Hispanic Whites. Women less likely had genotype 1 versus 2/3 than did men (OR 0.86 [0.78-0.94]). Versus non-Hispanic Whites, Asians (OR 0.38 [0.31-0.46]) and Blacks (OR 0.73 [0.63-0.84]) were less likely genotype1a than 1b; Hispanics (OR 1.3 [1.1-1.5]) and Native Americans (OR 1.9 [1.2-2.8]) more likely had genotype 1a than 1b. Patients age ≥65 years less likely had genotype 1a than 1b versus those age 45-64 (OR 0.34 [0.29-0.41]). The predominance of genotype 1 among all groups studied reinforces the need for new therapies targeting this genotype. Racial/ethnic variations in HCV genotype and subtype distribution must be considered in formulating new agents and novel strategies to successfully treat the diversity of hepatitis C patients. Copyright © 2012 Wiley Periodicals, Inc.

  20. High-density arrays of x-ray microcalorimeters for Constellation-X

    NASA Astrophysics Data System (ADS)

    Kilbourne, C. A.; Bandler, S. R.; Chervenak, J. A.; Figueroa-Feliciano, E.; Finkbeiner, F. M.; Iyomoto, N.; Kelley, R. L.; Porter, F. S.; Saab, T.; Sadleir, J.

    2005-12-01

    We have been developing x-ray microcalorimeters for the Constellation-X mission. Devices based on superconducting transition edge sensors (TES) have demonstrated the potential to meet the Constellation-X requirements for spectral resolution, speed, and array scale (> 1000 pixels) in a close-packed geometry. In our part of the GSFC/NIST collaboration on this technology development, we have been concentrating on the fabrication of arrays of pixels suitable for the Constellation-X reference configuration. We have fabricated 8x8 arrays with 0.25-mm pixels arranged with 92% fill factor. The pixels are based on Mo/Au TES and Bi/Cu absorbers. We have achieved a resolution of 4.9 eV FWHM at 6 keV in such devices. Studies of the thermal transport in our Bi/Cu absorbers have shown that, while there is room for improvement, for 0.25 mm pixels our existing absorber design is adequate to avoid line-broadening from position dependence caused by thermal diffusion. In order to push closer to the 4-eV requirement and 2-eV goal at 6 keV, we are refining the design of the TES and the interface to the absorber. For the 32x32 arrays ultimately needed for Constellation-X, signal lead routing and heatsinking will drive the design. We have had early successes with experiments in electroplating electrical vias and thermal busses into micro-machined features in silicon substrates. The next steps will be fabricating arrays that have all of the essential features of the required flight design, testing, and then engineering a prototype array for optimum performance.

  1. Implementation of a Collision Probability Prediction Technique for Constellation Maneuver Planning

    NASA Technical Reports Server (NTRS)

    Concha, Marco a.

    2007-01-01

    On March 22, 2006, the Space Technology 5 (ST5) constellation spacecraft were successfully delivered to orbit by a Pegasus XI, launch vehicle. An unexpected relative motion experienced by the constellation after orbit insertion brought about a problem. Soon after launch the observed relative position of the inert rocket body was between the leading and the middle spacecraft within the constellation. The successful planning and execution of an orbit maneuver that would create a fly-by of the rocket body was required to establish the.formation. This maneuver would create a close approach that needed to conform to predefined collision probability requirements. On April 21, 2006, the ST5 "155" spacecraft performed a large orbit maneuver and successfully passed the inert Pegasus 3rd Stage Rocket Body on April 30, 2006 15:20 UTC at a distance of 2.55 km with a Probability of Collision of less than 1.0E-06. This paper will outline the technique that was implemented to establish the safe planning and execution of the fly-by maneuver. The method makes use of Gaussian distribution models of state covariance to determine underlying probabilities of collision that arise under low velocity encounters. Specific numerical examples used for this analysis are discussed in detail. The mechanics of this technique are explained to foster deeper understanding of the concepts presented and to improve existing processes for use in future constellation maneuver planning.

  2. The Global Positioning System constellation as a space weather monitor

    NASA Astrophysics Data System (ADS)

    Morley, S.; Henderson, M. G.; Woodroffe, J. R.; Brito, T. V.

    2016-12-01

    The Global Positioning System (GPS) satellites are distributed across six orbital planes and follow near-circular orbits, with a 12 hour period, at an altitude of approximately 20200 km. The six orbital planes are distributed around the Earth and are nominally inclined at 55 degrees. Energetic particle detectors have been flown on the GPS constellation for more than two decades; by February 2016 there were 23 GPS satellites equipped with energetic particle instrumentation. The Combined X-ray Dosimeter (CXD), which is flown on 21 GPS satellites, has recently been cross-calibrated against electron data from the Van Allen Probes mission, demonstrating its utility for scientific research and radiation environment specification. Recently electron and proton flux data from these instruments, for the month of January 2014, have been publicly released. We will describe the GPS constellation from the perspective of its use as a monitor for space weather, review some of the key scientific results enabled by these instruments and show some recent observations from the constellation, including the 2015 St. Patrick's Day storm. Using data from multiple satellite missions we describe the dynamics of this storm in detail.

  3. Hyperspectral Cubesat Constellation for Natural Hazard Response

    NASA Technical Reports Server (NTRS)

    Mandl, Daniel; Crum, Gary; Ly, Vuong; Handy, Matthew; Huemmrich, Karl F.; Ong, Lawrence; Holt, Ben; Maharaja, Rishabh

    2016-01-01

    The authors on this paper are team members of the Earth Observing 1 (E0-1) mission which has flown an imaging spectrometer (hyperspectral) instrument called Hyperion for the past 15+ years. The satellite is able to image any spot on Earth in the nadir looking direction every 16 days and with slewing, of the satellite for up to a 23 degree view angle, any spot on the Earth can be imaged approximately every 2 to 3 days. EO-1 has been used to track many natural hazards such as wildfires, volcanoes and floods. An enhanced capability that has been sought is the ability to image natural hazards in a daily time series for space-based imaging spectrometers. The Hyperion cannot provide this capability on EO-1 with the present polar orbit. However, a constellation of cubesats, each with the same imaging spectrometer, positioned strategically can be used to provide daily coverage or even diurnal coverage, cost-effectively. This paper sought to design a cubesat constellation mission that would accomplish this goal and then to articulate the key tradeoffs.

  4. 75 FR 14467 - Notice of Inventory Completion: Pierce College District, Lakewood, WA, and Thomas Burke Memorial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-25

    ..., Pierce College District, 9401 Farwest Dr. SW, Lakewood, WA 98498, telephone (253) 912-3655, before April... DEPARTMENT OF THE INTERIOR National Park Service Notice of Inventory Completion: Pierce College... completion of an inventory of human remains in the control of the Pierce College District, Lakewood, WA, and...

  5. Weapon system simulation in flight (WaSiF)

    NASA Astrophysics Data System (ADS)

    Bartoldus, Klaus H.

    2005-05-01

    The research and technology demonstration program was co-funded by the Ministries of Defence of five European countries under the framework of the "EUropean Cooperation for the Long term in Defence" (EUCLID) MoU to include Germany, Italy, The Netherlands, Portugal and Turkey with considerable financial contribution from the industrial entities. EADS Military Aircraft Munich has led a team of seven industries and research centers, including Aermacchi of Italy, DutchSpace and NLR of The Netherlands, OGMA and INETI of Portugal and Marmara Research Center of Turkey. The purpose of the project was the design, realization and demonstration of an embedded real time simulation system allowing the combat training of operational aircrew in a virtual air defence scenario and threat environment against computer generated forces in the air and on the ground while flying on a real aircraft. The simulated scenario is focused on air-to-air beyond visual range engagements of fighter aircraft. WaSiF represents one of the first demonstrations of an advanced embedded real time training system onboard a fighter/training aircraft. The system is integrated onboard the MB339CX aircraft. The overall flight test activity covered a wide variety of test conditions for a total of 21 test flights; the operational airborne time of the WaSiF amounted to nearly 18 hours. The demonstration and evaluation were quite positive; the five-nation aircrew was very fond of their first encounter with the virtual world in the military flight training. A common view and approach towards Network Centric Warfare is but emerging. WaSiF in a future networked configuration holds lots of promise to serve the needs of Integrated Air Defence: Common training in a virtual environment.

  6. Constellation Stick Figures Convey Information about Gravity and Neutrinos

    NASA Astrophysics Data System (ADS)

    Mc Leod, David Matthew; Mc Leod, Roger David

    2008-10-01

    12/21/98, at America's Stonehenge, DMM detected, and drew, the full stick-figure equivalent of Canis Major, CM, as depicted by our Wolf Clan leaders, and many others. Profound, foundational physics is implied, since this occurred in the Watch House there, hours before the ``model rose.'' Similar configurations like Orion, Osiris of ancient Egypt, show that such figures are projected through solid parts of the Earth, as two-dimensional equivalents of the three-dimensional star constellations. Such ``sticks'' indicate that ``line equivalents'' connect the stars, and the physical mechanism projects outlines detectable by traditional cultures. We had discussed this ``flashlight'' effect, and recognized some of its implications. RDM states that the flashlight is a strong, distant neutrino source; the lines represent neutrinos longitudinally aligned in gravitational excitation, opaque, to earthbound, transient, transversely excited neutrinos. ``Sticks'' represent ``graviton'' detection. Neutrinos' longitudinal alignment accounts for the weakness of gravitational force.

  7. Analytical investigation of the dynamics of tethered constellations in Earth orbit, phase 2

    NASA Technical Reports Server (NTRS)

    Lorenzini, E.

    1985-01-01

    This Quarterly Report deals with the deployment maneuver of a single-axis, vertical constellation with three masses. A new, easy to handle, computer code that simulates the two-dimensional dynamics of the constellation has been implemented. This computer code is used for designing control laws for the deployment maneuver that minimizes the acceleration level of the low-g platform during the maneuver.

  8. Enhancements to TetrUSS for NASA Constellation Program

    NASA Technical Reports Server (NTRS)

    Pandya, Mohagna J.; Frink, Neal T.; Abdol-Hamid, Khaled S.; Samareh, Jamshid A,; Parlete, Edward B.; Taft, James R.

    2011-01-01

    The NASA Constellation program is utilizing Computational Fluid Dynamics (CFD) predictions for generating aerodynamic databases and design loads for the Ares I, Ares I-X, and Ares V launch vehicles and for aerodynamic databases for the Orion crew exploration vehicle and its launch abort system configuration. This effort presents several challenges to applied aerodynamicists due to complex geometries and flow physics, as well as from the juxtaposition of short schedule program requirements with high fidelity CFD simulations. NASA TetrUSS codes (GridTool/VGRID/USM3D) have been making extensive contributions in this effort. This paper will provide an overview of several enhancements made to the various elements of TetrUSS suite of codes. Representative TetrUSS solutions for selected Constellation program elements will be shown. Best practices guidelines and scripting developed for generating TetrUSS solutions in a production environment will also be described.

  9. APM for a Constellation Intersatellite Link - EM Qualification and Lessons Learned

    NASA Technical Reports Server (NTRS)

    Hartel, Frank; Kozilek, Horst

    2016-01-01

    For an Intersatellite Link (ISL) of a future constellation program, a study phase was initiated by ESA to design a mechanism for Radio Frequency communication. Airbus DS Friedrichshafen (ADSF) proposed a design based on the Antenna Pointing Mechanism (APM) family with modifications that met the stated needs of the constellation. A qualification program was started beginning in September 2015 to verify the launch and thermal loads and the equipment performance (Radio Frequency, Pointing, Microvibration and Magnetic Moment). Technical challenges identified with the Engineering Model will be discussed within this paper.

  10. V-FOR-WaTer - a new virtual research environment for environmental research

    NASA Astrophysics Data System (ADS)

    Strobl, Marcus; Azmi, Elnaz; Hassler, Sibylle; Mälicke, Mirko; Meyer, Jörg; Zehe, Erwin

    2017-04-01

    The preparation of heterogeneous datasets for scientific analysis is still a demanding task. Data preprocessing for hydrological models typically involves gathering datasets from different sources, extensive work within geoinformation systems, data transformation, the generation of computational grids and the definition of initial and boundary conditions. V-FOR-WaTer, a standardized and scalable data hub with compatible analysis tools, will ease comprehensive studies and significantly reduce data preparation time. The idea behind V-FOR-WaTer is to bring together various datasets (e.g. point measurements, 2D/3D data, time series data) from different sources (e.g. gathered in research projects, or as part of regular monitoring of state offices) and to provide common as well as innovative scaling tools in space and time to generate a coherent data grid. Each dataset holds detailed standardized metadata to ensure usability of the data, offer a comprehensive search function and provide reference information for appropriate citation of the dataset creators. V-FOR-WaTer includes a basis of data and tools, but its purpose is to grow by users who extend the virtual research environment with their own tools and research data. Researchers who upload new data or tools can receive a digital object identifier, or protect their data and tools from others until publication. Access to data and tools provided from V-FOR-WaTer happens via an easy-to-use web portal. Due to its modular architecture the portal is ready to be extended with new tools and features and also offers interfaces to Matlab, Python and R.

  11. A capsule/lipopolysaccharide/MLST genotype D/L6/ST11 of Pasteurella multocida is likely to be strongly associated with swine respiratory disease in China.

    PubMed

    Peng, Zhong; Wang, Haonan; Liang, Wan; Chen, Yibao; Tang, Xibiao; Chen, Huanchun; Wu, Bin

    2018-01-01

    Pasteurella multocida is a leading cause of respiratory disease in pigs worldwide. In this study, we determined the genetic characteristics of 115 P. multocida isolates from the lungs of pigs with respiratory disease in China in 2015 using capsular typing, lipopolysaccharide (LPS) genotyping, and virulence genotyping based on the detection of virulence-associated genes. The results showed that the isolates belonged to three capsular types: A (49.6%), D (46.1%), and nontypable (4.3%); and two LPS genotypes: L3 (22.6%) and L6 (77.4%). When combining the capsular types with the LPS genotypes, a genotype group D: L6 (46.1%) was the most prevalent among the strains. Among the 23 virulence-associated genes detected in this study, a small number of them displayed a certain level of "genotype-preference". We found that pfhA, hgbA, and hgbB had a close association with P. multocida LPS genotypes, while tadD was more associated with P. multocida capsular types. In addition, multilocus sequence typing (MLST) on 40 P. multocida isolates identified four sequence types: ST3, ST10, ST11, and ST16, and the distribution of ST11 was significantly higher than the other MLST genotypes. Interestingly, all of the ST11 isolates detected in this study were genotype D: L6 strains and they were 100% positive for hgbB. Our data suggest that a capsule/LPS/MLST genotype D/L6/ST11 is likely to be strongly associated with respiratory clinical manifestation of the disease in pigs.

  12. Adaptation and Re-Use of Spacecraft Power System Models for the Constellation Program

    NASA Technical Reports Server (NTRS)

    Hojnicki, Jeffrey S.; Kerslake, Thomas W.; Ayres, Mark; Han, Augustina H.; Adamson, Adrian M.

    2008-01-01

    NASA's Constellation Program is embarking on a new era of space exploration, returning to the Moon and beyond. The Constellation architecture will consist of a number of new spacecraft elements, including the Orion crew exploration vehicle, the Altair lunar lander, and the Ares family of launch vehicles. Each of these new spacecraft elements will need an electric power system, and those power systems will need to be designed to fulfill unique mission objectives and to survive the unique environments encountered on a lunar exploration mission. As with any new spacecraft power system development, preliminary design work will rely heavily on analysis to select the proper power technologies, size the power system components, and predict the system performance throughout the required mission profile. Constellation projects have the advantage of leveraging power system modeling developments from other recent programs such as the International Space Station (ISS) and the Mars Exploration Program. These programs have developed mature power system modeling tools, which can be quickly modified to meet the unique needs of Constellation, and thus provide a rapid capability for detailed power system modeling that otherwise would not exist.

  13. Tracing the Energetics of the Universe with Constellation-X: Example Scientific Investigations

    NASA Technical Reports Server (NTRS)

    Hornschemeier, Ann

    2008-01-01

    Constellation-X will enable us to trace the energetics of a broad range of astrophysical phenomena owing to its capabilities for high spectral resolution X-ray spectroscopy. The dominant baryonic component of galaxy clusters and groups resides in the X-ray bandpass, and the hot phase of the ISM in galaxies harbors the heavy metal production from previous generation of stars. This talk will focus on a few example science questions that are expected to be important during the Constellation-X era. These include the nature of the missing baryons expected to reside in the hot portion of the Warm Hot Intergalactic Medium, which Constellation-X will address via absorption spectroscopy studies of background AGN. We will also discuss spatially resolved spectroscopy of metal enrichment and the effects of turbulence in clusters & groups and of starburst galaxy winds which deposit energy & metals into the Intergalactic Medium.

  14. Fouled Anchors: The CONSTELLATION Question Answered

    DTIC Science & Technology

    1991-09-01

    brought to Baltimore in 1955 and tuned over to the Constellation Commuttee of the Flag House Associat on for public display. In response to Howard...Josephus Daniels spoke before the House of Representatives Committee on Naval Affairs in 1914, supporting a bill to fund restoration, he presented a...where she was publicly exhibited as having been built in Baltimore in 1797. In 1928, the Star-Spangled Banner Flag House Association, incorporated in 1927

  15. 77 FR 35862 - Safety Zone; Fleet Week Maritime Festival, Pier 66 Elliott Bay, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-15

    ... Zone; Fleet Week Maritime Festival, Pier 66 Elliott Bay, Seattle, WA AGENCY: Coast Guard, DHS. ACTION... Festival's Pier 66 Safety Zone in Elliott Bay, WA from 8 a.m. until 8 p.m. on August 1, 2012, however, it... Fleet Week Maritime Festival in 33 CFR 165.1330 on August 1, 2012, from 8 a.m. until 8 p.m.; however, it...

  16. 33 CFR 100.1309 - Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA. 100.1309 Section 100.1309 Navigation and Navigable Waters... WATERS § 100.1309 Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA. (a...

  17. 33 CFR 100.1309 - Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA. 100.1309 Section 100.1309 Navigation and Navigable Waters... WATERS § 100.1309 Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA. (a...

  18. 33 CFR 100.1309 - Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA. 100.1309 Section 100.1309 Navigation and Navigable Waters... WATERS § 100.1309 Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA. (a...

  19. 33 CFR 100.1309 - Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA. 100.1309 Section 100.1309 Navigation and Navigable Waters... WATERS § 100.1309 Special Local Regulation; Olympia Harbor Days Tug Boat Races, Budd Inlet, WA. (a...

  20. Life Support Requirements and Challenges for NASA's Constellation Program

    NASA Technical Reports Server (NTRS)

    Carasquillo, Robyn

    2007-01-01

    NASA's Constellation Program, which includes the mission objectives of establishing a permanently-manned lunar Outpost, and the exploration of Mars, poses new and unique challenges for human life support systems that will require solutions beyond the Shuttle and International Space Station state of the art systems. In particular, the requirement to support crews for 210 days duration at the lunar outpost with limited resource resupply capability wilt require closed-loop regenerative life support systems with minimal expendables. Planetary environmental conditions such as lunar dust and extreme temperatures, as well as the capability to support frequent and extended-duration EVA's will be particularly challenging. This presentation will summarize the key program and mission life support requirements for the Constellation Program and the unique challenges they present for technology and architecture development.

  1. 2. A 1993 'rephotograph' of the 1917 context view (WA203A1) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. A 1993 're-photograph' of the 1917 context view (WA-203-A-1) looking east along Farragut Avenue. Building 78 is the brick building on right. Building 59 (Pattern Shop) is the brick building on left side of street, just beyond the tallest modern building. The 1917 view was taken from a hill which was later removed. The 1993 view was taken from a lift at the estimated height/position of the former hill. - Puget Sound Naval Shipyard, Administration Building, Farragut Avenue, Bremerton, Kitsap County, WA

  2. Constellation Launch Vehicles Overview

    NASA Technical Reports Server (NTRS)

    Cook, Steve; Fragola, Joseph R.; Priskos, Alex; Davis, Danny; Kaynard, Mike; Hutt, John; Davis, Stephan; Creech, Steve

    2009-01-01

    This slide presentation reviews the current status of the launch vehicles associated with the Constellation Program. These are the Ares I and the Ares V. An overview of the Ares launch vehicles is included. The presentation stresses that the major criteria for the Ares I launcher is the safety of the crew, and the presentation reviews the various features that are designed to assure that aim. The Ares I vehicle is being built on a foundation of proven technologies, and the Ares V will give NASA unprecedented performance and payload volume that can enable a range of future missions. The CDs contain videos of scenes from various activities surrounding the design, construction and testing of the vehicles.

  3. The autonomous sciencecraft constellations

    NASA Technical Reports Server (NTRS)

    Sherwood, R. L.; Chien, S.; Castano, R.; Rabideau, G.

    2003-01-01

    The Autonomous Sciencecraft Experiment (ASE) will fly onboard the Air Force TechSat 21 constellation of three spacecraft scheduled for launch in 2006. ASE uses onboard continuous planning, robust task and goal-based execution, model-based mode identification and reconfiguration, and onboard machine learning and pattern recognition to radically increase science return by enabling intelligent downlink selection and autonomous retargeting. In this paper we discuss how these AI technologies are synergistically integrated in a hybrid multi-layer control architecture to enable a virtual spacecraft science agent. Demonstration of these capabilities in a flight environment will open up tremendous new opportunities in planetary science, space physics, and earth science that would be unreachable without this technology.

  4. High-density arrays of x-ray microcalorimeters for Constellation-X

    NASA Astrophysics Data System (ADS)

    Kilbourne, Caroline A.; Bandler, Simon R.; Brown, Ari D.; Chervenak, James A.; Figueroa-Feliciano, Enectali; Finkbeiner, Fred M.; Iyomoto, Naoko; Kelley, Richard L.; Porter, F. Scott; Saab, Tarek; Sadleir, John; White, Jennifer

    2006-06-01

    We have been developing x-ray microcalorimeters for the Constellation-X mission. Devices based on superconducting transition-edge sensors (TES) have demonstrated the potential to meet the Constellation-X requirements for spectral resolution, speed, and array scale (> 1000 pixels) in a close-packed geometry. In our part of the GSFC/NIST collaboration on this technology development, we have been concentrating on the fabrication of arrays of pixels suitable for the Constellation-X reference configuration. We have fabricated 8x8 arrays with 0.25-mm pixels arranged with 92% fill factor. The pixels are based on Mo/Au TES and Bi/Cu or Au/Bi absorbers. We have achieved a resolution of 4.0 eV FWHM at 6 keV in such devices, which meets the Constellation-X resolution requirement at 6 keV. Studies of the thermal transport in our Bi/Cu absorbers have shown that, while there is room for improvement, for 0.25-mm pixels the standard absorber design is adequate to avoid unacceptable line-broadening from position dependence caused by thermal diffusion. In order to improve reproducibility and to push closer to the 2-eV goal at 6 keV, however, we are refining the design of the TES and the interface to the absorber. Recent efforts to introduce a barrier layer between the Bi and the Mo/Au to avoid variable interface chemistry and thus improve the reproducibility of device characteristics have thus far yielded unsatisfactory results. However, we have developed a new set of absorber designs with contacts to the TES engineered to allow contact only in regions that do not serve as the active thermometer. We have further constrained the design so that a low-resistance absorber will not electrically short the TES. It is with such a design that we have achieved 4.0 eV resolution at 6 keV.

  5. Going Beyond Einstein with the Constellation-X Mission

    NASA Technical Reports Server (NTRS)

    White, Nicholas

    2007-01-01

    The Constellation-X mission will address the questions: "What happens to matter close to a black hole?" and "What is Dark Energy?" These questions are central to the NASA Beyond Einstein Program, where Constellation-X plays a central role. The mission will address these questions by using high throughput X-ray spectroscopy to observe the effects of strong gravity close to the event horizon of black holes, and to observe the formation and evolution of clusters of galaxies in order to precisely determine Cosmological parameters. To achieve these primary science goals requires a factor of 25-100 increase in sensitivity for high resolution X-ray spectroscopy.'The mission will also perform routine high-resolution X-ray spectroscopy of faint 2nd extended X-ray source populations. This will provide diagnostic information such as density, elemental abundances, velocity; and ionization state for a wide range of astrophysical problems, including new constraints on the Neutron Star equation of state.

  6. 75 FR 53688 - Constellation Mystic Power, LLC; Supplemental Notice That Initial Market-Based Rate Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER10-2281-000] Constellation... proceeding of Constellation Mystic Power, LLC's application for market-based rate authority, with an... CFR part 34, of future issuances of securities and assumptions of liability. Any person desiring to...

  7. 78 FR 32385 - Exelon Generation Company, LLC; CER Generation II, LLC; Constellation Mystic Power, LLC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL13-64-000] Exelon Generation Company, LLC; CER Generation II, LLC; Constellation Mystic Power, LLC; Constellation NewEnergy...) Rules of Practice and Procedure, 18 CFR 385.207, Exelon Generation Company, LLC, CER Generation II, LLC...

  8. The Afternoon Constellation: A Formation of Earth Observing Systems for the Atmosphere and Hydrosphere

    NASA Technical Reports Server (NTRS)

    Schoeberl, Mark R.

    2002-01-01

    Two of the large EOS observatories, Aqua (formerly EOS-PM) and Aura (formerly EOS-CHEM) will fly is nearly the same inclination with 1:30 PM -15 min ascending node equatorial crossing times. Between Aura and Aqua a series of smaller satellites will be stationed: Cloudsat, CALYPSO (formerly PICASSO-CENA), and PARASOL. This constellation of low earth orbit satellites will provide an unprecedented opportunity to make near simultaneous atmospheric cloud and aerosol observations. This paper will provide details of the science opportunity and describe the sensor types for the afternoon constellation. This constellation by accretion provides a prototype for the Earth Science Vision sensor web and represent the building books for a future web structure.

  9. 78 FR 2428 - Notice of Intent To Repatriate Cultural Items: Northwest Museum of Arts & Culture, Spokane, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... & Culture, also the Eastern Washington State Historical Society, Spokane, WA, that meet the definition of... Intent To Repatriate Cultural Items: Northwest Museum of Arts & Culture, Spokane, WA AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Northwest Museum of Arts & Culture, also known as...

  10. 77 FR 33307 - Columbia Unlimited Hydroplane Races; Kennewick, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ...-AA08 Columbia Unlimited Hydroplane Races; Kennewick, WA AGENCY: Coast Guard, DHS. ACTION: Notice of... Unlimited Hydroplane Races from Tuesday, July 24th through Sunday July 29th, 2012. This action is necessary... Unlimited Hydroplane Races (Water Follies). During the enforcement period, no vessel may operate in this...

  11. Spatial Sense and Perspective: A 3-D Model of the Orion Constellation

    NASA Astrophysics Data System (ADS)

    Heyer, I.; Slater, T. F.; Slater, S. J.

    2012-08-01

    Building a scale model of the Orion constellation provides spatial perspective for students studying astronomy. For this activity, students read a passage from literature that refers to stars being strange when seen from a different point of view. From a data set of the seven major stars of Orion they construct a 3-D distance scale model. This involves the subject areas of astronomy, mathematics, literature and art, as well as the skill areas of perspective, relative distances, line-of-sight, and basic algebra. This model will appear from one side exactly the way we see it from Earth. But when looking at it from any other angle the familiar constellation will look very alien. Students are encouraged to come up with their own names and stories to go with these new constellations. This activity has been used for K-12 teacher professional development classes, and would be most suitable for grades 6-12.

  12. Space Technology 5: Enabling Future Micro-Sat Constellation Science Missions

    NASA Technical Reports Server (NTRS)

    Carlisle, Candace C.; Webb, Evan H.

    2004-01-01

    The Space Technology 5 (ST-5) Project is part of NASA s New Millennium Program. ST-5 will consist of a constellation of three micro-satellites, each approximately 25 kg in mass. The mission goals are to demonstrate the research-quality science capability of the ST-5 spacecraft; to operate the three spacecraft as a constellation; and to design, develop and flight-validate three capable micro-satellites with new technologies. ST-5 is designed to measurably raise the utility of small satellites by providing high functionality in a low mass, low power, and low volume package. The whole of ST-5 is greater than the sum of its parts: the collection of components into the ST-5 spacecraft allows it to perform the functionality of a larger scientific spacecraft on a micro-satellite platform. The ST-5 mission was originally designed to be launched as a secondary payload into a Geosynchronous Transfer Orbit (GTO). Recently, the mission has been replanned for a Pegasus XL dedicated launch into an elliptical polar orbit. A three-month flight demonstration phase, beginning in March 2006, will validate the ability to perform science measurements, as well as the technologies and constellation operations. ST- 5 s technologies and concepts will then be transferred to future micro-sat science missions.

  13. Space Technology 5: Enabling Future Micro-Sat Constellation Science Missions

    NASA Technical Reports Server (NTRS)

    Carlisle, Candace C.; Webb, Evan H.; Slavin, James A.

    2004-01-01

    The Space Technology 5 (ST-5) Project is part of NASA s New Millennium Program. ST-5 will consist of a constellation of three micro-satellites, each approximately 25 kg in mass. The mission goals are to demonstrate the research-quality science capability of the ST-5 spacecraft, to operate the three spacecraft as a constellation; and to design, develop and flight-validate three capable micro-satellites with new technologies. ST-5 is designed to measurably raise the utility of small satellites by providing high functionality in a low mass, low power, and low volume package. The whole of ST-5 is greater than the sum of its parts: the collection of components into the ST-5 spacecraft allows it to perform the functionality of a larger scientific spacecraft on a micro-satellite platform. The ST-5 mission was originally designed to be launched as a secondary payload into a Geosynchronous Transfer Orbit (GTO). Recently, the mission has been replanned for a Pegasus XL dedicated launch into an elliptical polar orbit. A three-month flight demonstration phase, beginning in March 2006, will validate the ability to perform science measurements, as well as the technologies and constellation operations. ST- 5 s technologies and concepts will then be transferred to future micro-sat science missions.

  14. Supporting nurse mentor development: An exploration of developmental constellations in nursing mentorship practice.

    PubMed

    MacLaren, Julie-Ann

    2018-01-01

    Supervised practice as a mentor is currently an integral component of nurse mentor education. However, workplace education literature tends to focus on dyadic mentor-student relationships rather than developmental relationships between colleagues. This paper explores the supportive relationships of nurses undertaking a mentorship qualification, using the novel technique of constellation development to determine the nature of workplace support for this group. Semi-structured interviews were conducted with three recently qualified nurse mentors. All participants developed a mentorship constellation identifying colleagues significant to their own learning in practice. These significant others were also interviewed alongside practice education, and nurse education leads. Constellations were analysed in relation to network size, breadth, strength of relationships, and attributes of individuals. Findings suggest that dyadic forms of supervisory mentorship may not offer the range of skills and attributes that developing mentors require. Redundancy of mentorship attributes within the constellation (overlapping attributes between members) may counteract problems caused when one mentor attempts to fulfil all mentorship roles. Wider nursing teams are well placed to provide the support and supervision required by mentors in training. Where wider and stronger networks were not available to mentorship students, mentorship learning was at risk. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  15. Global Earth Outgoing Radiation From A Constellation Of Satellites: Proof-Of-Concept Study

    NASA Astrophysics Data System (ADS)

    Gristey, J. J.; Chiu, J. Y. C.; Gurney, R. J.; Han, S. C.; Morcrette, C. J.

    2017-12-01

    The flux of radiation exiting at the top of the atmosphere, referred to as Earth Outgoing Radiation (EOR), constitutes a vital component of the Earth's energy budget. Since EOR is inherently connected to the rapidly evolving scene from which the radiation originates and exhibits large regional variations, it is of paramount importance that we can monitor EOR at a sufficient frequency and spatial scale for weather and climate studies. Achieving these criteria remains challenging using traditional measurement techniques. However, explosive development in small satellite technology and sensor miniaturisation has paved a viable route for measurements to be made from a constellation of satellites in different orbits. This offers an exciting new opportunity to make observations of EOR with both global coverage and high temporal resolution for the first time. To assess the potential of the constellation approach for observing EOR we perform a series of observing system simulation experiments. We will outline a baseline constellation configuration capable of sampling the Earth with unprecedented temporal resolution. Using this configuration and a sophisticated deconvolution technique, we demonstrate how to recover synoptic-scale global EOR to the accuracy required to understand Earth's global energy budget. Finally, we will reveal the impact of various modifications to the constellation configuration and provide recommendations for the community.

  16. WaLIDD score, a new tool to diagnose dysmenorrhea and predict medical leave in university students

    PubMed Central

    Teherán, Aníbal A; Piñeros, Luis Gabriel; Pulido, Fabián; Mejía Guatibonza, María Camila

    2018-01-01

    Background Dysmenorrhea is a frequent and misdiagnosed symptom affecting the quality of life in young women. A working ability, location, intensity, days of pain, dysmenorrhea (WaLIDD) score was designed to diagnose dysmenorrhea and to predict medical leave. Methods This cross-sectional design included young medical students, who completed a self-administered questionnaire that contained the verbal rating score (VRS; pain and drug subscales) and WaLIDD scales. The correlation between scales was established through Spearman test. The area under the receiver operating characteristic (ROC) curve, sensitivity, specificity, and likelihood ratio (LR +/−) were evaluated to diagnose students availing medical leave due to dysmenorrhea; moreover, to predict medical leave in students with dysmenorrhea, a binary logistic regression was performed. Results In all, 585 students, with a mean age of 21 years and menarche at 12 years, participated. Most of them had regular cycles, 5 days of menstrual blood flow and 1–2 days of lower abdominal pain. The WaLIDD scale presented an adequate internal consistency and strong correlation with VRS subscales. With a cutoff of >6 for WaLIDD and 2 for VRS subscales (drug subscale and pain subscale) to identify students with dysmenorrhea, these scales presented an area under the curve (AUC) ROC of 0.82, 0.62, and 0.67, respectively. To identify students taking medical leave due to dysmenorrhea, WaLIDD (cutoff >9) and VRS subscales (cutoff >2) presented an AUC ROC of 0.97, 0.68, and 0.81; moreover, the WaLIDD scale showed a good LR +14.2 (95% CI, 13.5–14.9), LR −0.00 (95% CI, undefined), and predictive risk (OR 5.38; 95% CI, 1.78–16.2). Conclusion This research allowed a comparison between two multidimensional scales regarding their capabilities, one previously validated and a new one, to discriminate among the general population of medical students, among those with dysmenorrhea or those availing medical leave secondary to dysmenorrhea

  17. Point pattern match-based change detection in a constellation of previously detected objects

    DOEpatents

    Paglieroni, David W.

    2016-06-07

    A method and system is provided that applies attribute- and topology-based change detection to objects that were detected on previous scans of a medium. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, detection strength, size, elongation, orientation, etc. The locations define a three-dimensional network topology forming a constellation of previously detected objects. The change detection system stores attributes of the previously detected objects in a constellation database. The change detection system detects changes by comparing the attributes and topological consistency of newly detected objects encountered during a new scan of the medium to previously detected objects in the constellation database. The change detection system may receive the attributes of the newly detected objects as the objects are detected by an object detection system in real time.

  18. New Satellite Constellation Uses Radio Occultation to Monitor Space Weather

    NASA Astrophysics Data System (ADS)

    Kumar, Mohi

    2006-05-01

    A constellation of six satellites, expected to enhance space weather research, improve terrestrial meteorology forecasts, and monitor climate change, were launched 15 April from Vandenberg Air Force Base, Calif.

  19. 76 FR 3014 - Security Zone; Protection of Military Cargo, Captain of the Port Zone Puget Sound, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-19

    ... Coast Guard will enforce the Blair Waterway security zone in Commencement Bay, WA for protection of... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket No. USCG-2011-0015] Security Zone; Protection of Military Cargo, Captain of the Port Zone Puget Sound, WA AGENCY: Coast Guard, DHS...

  20. Phenotypic and Genotypic Characterization of Enterobacteriaceae Producing Oxacillinase-48–Like Carbapenemases, United States

    PubMed Central

    Zhu, Wenming; de Man, Tom J.B.; Avillan, Johannetsy J.; Anderson, Karen F.; Lonsway, David R.; Rowe, Lori A.; Batra, Dhwani; Rasheed, J. Kamile; Limbago, Brandi M.

    2018-01-01

    Oxacillinase (OXA)–48–like carbapenemases remain relatively uncommon in the United States. We performed phenotypic and genotypic characterization of 30 Enterobacteriaceae producing OXA-48–like carbapenemases that were recovered from patients during 2010–2014. Isolates were collected from 12 states and not associated with outbreaks, although we could not exclude limited local transmission. The alleles β-lactamase OXA-181 (blaOXA-181) (43%), blaOXA-232 (33%), and blaOXA-48 (23%) were found. All isolates were resistant to ertapenem and showed positive results for the ertapenem and meropenem modified Hodge test and the modified carbapenem inactivation method; 73% showed a positive result for the Carba Nordmann–Poirel test. Whole-genome sequencing identified extended-spectrum β-lactamase genes in 93% of isolates. In all blaOXA-232 isolates, the gene was on a ColKP3 plasmid. A total of 12 of 13 isolates harboring blaOXA-181 contained the insertion sequence ΔISEcp1. In all isolates with blaOXA-48, the gene was located on a TN1999 transposon; these isolates also carried IncL/M plasmids. PMID:29553324

  1. (WA80 collaboration, Muenster, W. Germany, April 17--21, 1989): Foreign trip report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Young, G.R.

    1989-05-11

    The traveler attended a WA80 collaboration meeting held at the University of Muenster, FRG. The status of various experimental analyses was reviewed and discussed, as was the status of various papers in preparation. Plans for a joint NA35-WA80 proposal to use the lead beams to be available at the SPS in 1993 were advanced in a meeting which included several WA80 persons plus Reinhard Stock of NA35 and Rudolf Bock of GSI. Plans for a prototype of a high-resolution photon calorimeter were made. ORNL is asked to prepare much of this for a test run in December 1989. Further plansmore » for the 1990 and 1991 extended beam times at CERN with /sup 32/S were made. ORNL is asked to participate in a large upgrade of the present trigger and to collaborate with Muenster in a large upgrade and expansion of the present photon calorimeter. Other items include a rearrangement of the experimental area (GSI), new multiplicity counters (Lund-LBL), and a new data-acquisition system (GSI-Muenster).« less

  2. Comet Hale-Bopp in the constellation Andromeda

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Comet Hale-Bopp was photographed in the constellation Andromeda by George Shelton, photographer for The Bionetics Corp., at 8:14 p.m. on March 31, 1997, from Merritt Island, Florida, close to the Kennedy Space Center. During this 24-hour period, Comet Hale- Bopp is making its closest approach to the Sun.

  3. Best Practices Case Study: Devoted Builders, LLC, Mediterrtanean Villas, Pasco,WA

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2010-12-01

    Devoted Builders of Kennewick, WA worked with Building America's BIRA team to achieve the 50% Federal tax credit level energy savings on 81 homes at its Mediterranean Villas community in eastern Washington.

  4. Ground Plane and Near-Surface Thermal Analysis for NASA's Constellation Program

    NASA Technical Reports Server (NTRS)

    Gasbarre, Joseph F.; Amundsen, Ruth M.; Scola, Salvatore; Leahy, Frank F.; Sharp, John R.

    2008-01-01

    Most spacecraft thermal analysis tools assume that the spacecraft is in orbit around a planet and are designed to calculate solar and planetary fluxes, as well as radiation to space. On NASA Constellation projects, thermal analysts are also building models of vehicles in their pre-launch condition on the surface of a planet. This process entails making some modifications in the building and execution of a thermal model such that the radiation from the planet, both reflected albedo and infrared, is calculated correctly. Also important in the calculation of pre-launch vehicle temperatures are the natural environments at the vehicle site, including air and ground temperatures, sky radiative background temperature, solar flux, and optical properties of the ground around the vehicle. A group of Constellation projects have collaborated on developing a cohesive, integrated set of natural environments that accurately capture worst-case thermal scenarios for the pre-launch and launch phases of these vehicles. The paper will discuss the standardization of methods for local planet modeling across Constellation projects, as well as the collection and consolidation of natural environments for launch sites. Methods for Earth as well as lunar sites will be discussed.

  5. Data from SILAC-based quantitative analysis of lysates from mouse microglial cells treated with Withaferin A (WA).

    PubMed

    Narayan, Malathi; Seeley, Kent W; Jinwal, Umesh K

    2016-06-01

    Mass spectrometry data collected in a study analyzing the effect of withaferin A (WA) on a mouse microglial (N9) cell line is presented in this article. Data was collected from SILAC-based quantitative analysis of lysates from mouse microglial cells treated with either WA or DMSO vehicle control. This article reports all the proteins that were identified in this analysis. The data presented here is related to the published research article on the effect of WA on the differential regulation of proteins in mouse microglial cells [1]. Mass spectrometry data has also been deposited in the ProteomeXchange with the identifier PXD003032.

  6. Constructing lightning towers for the Constellation Program and

    NASA Image and Video Library

    2007-11-09

    On Launch Pad 39B at NASA's Kennedy Space Center, pilings are being pounded into the ground to help construct lightning towers for the Constellation Program and Ares/Orion launches. Pad B will be the site of the first Ares vehicle launch, including Ares I-X which is scheduled for April 2009.

  7. Challenges and Opportunities for Mainstreaming Climate Change Adaptation into WaSH Development Planning in Ghana.

    PubMed

    Alhassan, Salley; Hadwen, Wade L

    2017-07-10

    Climate change threatens water, sanitation and hygiene (WaSH) facilities and services, as these are intimately linked to the water cycle and are vulnerable to changes in the quantity and quality of available water resources. Floods and droughts, which pollute and reduce water delivery respectively, have now become a perennial issue to deal with in the northern regions of Ghana. This study aimed to assess the degree to which climate change adaptation measures are mainstreamed into the water, sanitation and hygiene (WaSH) development planning process in Ghana. Stakeholders from government and non-government agencies were interviewed to gain perspectives on the threat of climate change, the inclusion of climate change in WaSH planning and the barriers preventing mainstreaming. Despite awareness of climate change, adaptation measures have not been considered, and the immediate WaSH needs remain the priority. Overall, stakeholders felt the adaptive capacity of the Municipality was low and that mainstreaming has not yet occurred. Despite the lack of progress, there are great opportunities for mainstreaming climate change adaptation into planning through increasing awareness and capacity, legislative and institutional changes and the development of participatory systems to provide early warning systems and disaster risk analyses that will inform future planning.

  8. Challenges and Opportunities for Mainstreaming Climate Change Adaptation into WaSH Development Planning in Ghana

    PubMed Central

    2017-01-01

    Climate change threatens water, sanitation and hygiene (WaSH) facilities and services, as these are intimately linked to the water cycle and are vulnerable to changes in the quantity and quality of available water resources. Floods and droughts, which pollute and reduce water delivery respectively, have now become a perennial issue to deal with in the northern regions of Ghana. This study aimed to assess the degree to which climate change adaptation measures are mainstreamed into the water, sanitation and hygiene (WaSH) development planning process in Ghana. Stakeholders from government and non-government agencies were interviewed to gain perspectives on the threat of climate change, the inclusion of climate change in WaSH planning and the barriers preventing mainstreaming. Despite awareness of climate change, adaptation measures have not been considered, and the immediate WaSH needs remain the priority. Overall, stakeholders felt the adaptive capacity of the Municipality was low and that mainstreaming has not yet occurred. Despite the lack of progress, there are great opportunities for mainstreaming climate change adaptation into planning through increasing awareness and capacity, legislative and institutional changes and the development of participatory systems to provide early warning systems and disaster risk analyses that will inform future planning. PMID:28698518

  9. Optimal Constellation Design for Maximum Continuous Coverage of Targets Against a Space Background

    DTIC Science & Technology

    2012-05-31

    constellation is considered with the properties shown in Table 13. The parameter hres refers to the number of equally spaced offset planes in which cross...mean anomaly 180 ◦ M0i mean anomaly of lead satellite at epoch 0 ◦ R omni-directional sensor range 5000 km m initial polygon resolution 50 PPC hres ...a Walker Star. Idealized parameters for the Iridium constellation are shown in Table 14. The parameter hres refers to the number of equally spaced

  10. Reassortment between Swine H3N2 and 2009 Pandemic H1N1 in the United States Resulted in Influenza A Viruses with Diverse Genetic Constellations with Variable Virulence in Pigs

    PubMed Central

    Rajão, Daniela S.; Walia, Rasna R.; Campbell, Brian; Gauger, Phillip C.; Janas-Martindale, Alicia; Killian, Mary Lea

    2016-01-01

    ABSTRACT Repeated spillovers of the H1N1 pandemic virus (H1N1pdm09) from humans to pigs resulted in substantial evolution of influenza A viruses infecting swine, contributing to the genetic and antigenic diversity of influenza A viruses (IAV) currently circulating in swine. The reassortment with endemic swine viruses and maintenance of some of the H1N1pdm09 internal genes resulted in the circulation of different genomic constellations in pigs. Here, we performed a whole-genome phylogenetic analysis of 368 IAV circulating in swine from 2009 to 2016 in the United States. We identified 44 different genotypes, with the most common genotype (32.33%) containing a clade IV-A HA gene, a 2002-lineage NA gene, an M-pdm09 gene, and remaining gene segments of triple reassortant internal gene (TRIG) origin. To understand how different genetic constellations may relate to viral fitness, we compared the pathogenesis and transmission in pigs of six representative genotypes. Although all six genotypes efficiently infected pigs, they resulted in different degrees of pathology and viral shedding. These results highlight the vast H3N2 genetic diversity circulating in U.S. swine after 2009. This diversity has important implications in the control of this disease by the swine industry, as well as a potential risk for public health if swine-adapted viruses with H1N1pdm09 genes have an increased risk to humans, as occurred in the 2011-2012 and 2016 human variant H3N2v cases associated with exhibition swine. IMPORTANCE People continue to spread the 2009 H1N1 pandemic (H1N1pdm09) IAV to pigs, allowing H1N1pdm09 to reassort with endemic swine IAV. In this study, we determined the 8 gene combinations of swine H3N2 IAV detected from 2009 to 2016. We identified 44 different genotypes of H3N2, the majority of which contained at least one H1N1pdm09 gene segment. We compared six representative genotypes of H3N2 in pigs. All six genotypes efficiently infected pigs, but they resulted in different

  11. Reassortment between Swine H3N2 and 2009 Pandemic H1N1 in the United States Resulted in Influenza A Viruses with Diverse Genetic Constellations with Variable Virulence in Pigs.

    PubMed

    Rajão, Daniela S; Walia, Rasna R; Campbell, Brian; Gauger, Phillip C; Janas-Martindale, Alicia; Killian, Mary Lea; Vincent, Amy L

    2017-02-15

    Repeated spillovers of the H1N1 pandemic virus (H1N1pdm09) from humans to pigs resulted in substantial evolution of influenza A viruses infecting swine, contributing to the genetic and antigenic diversity of influenza A viruses (IAV) currently circulating in swine. The reassortment with endemic swine viruses and maintenance of some of the H1N1pdm09 internal genes resulted in the circulation of different genomic constellations in pigs. Here, we performed a whole-genome phylogenetic analysis of 368 IAV circulating in swine from 2009 to 2016 in the United States. We identified 44 different genotypes, with the most common genotype (32.33%) containing a clade IV-A HA gene, a 2002-lineage NA gene, an M-pdm09 gene, and remaining gene segments of triple reassortant internal gene (TRIG) origin. To understand how different genetic constellations may relate to viral fitness, we compared the pathogenesis and transmission in pigs of six representative genotypes. Although all six genotypes efficiently infected pigs, they resulted in different degrees of pathology and viral shedding. These results highlight the vast H3N2 genetic diversity circulating in U.S. swine after 2009. This diversity has important implications in the control of this disease by the swine industry, as well as a potential risk for public health if swine-adapted viruses with H1N1pdm09 genes have an increased risk to humans, as occurred in the 2011-2012 and 2016 human variant H3N2v cases associated with exhibition swine. People continue to spread the 2009 H1N1 pandemic (H1N1pdm09) IAV to pigs, allowing H1N1pdm09 to reassort with endemic swine IAV. In this study, we determined the 8 gene combinations of swine H3N2 IAV detected from 2009 to 2016. We identified 44 different genotypes of H3N2, the majority of which contained at least one H1N1pdm09 gene segment. We compared six representative genotypes of H3N2 in pigs. All six genotypes efficiently infected pigs, but they resulted in different degrees of lung damage

  12. Constructing lightning towers for the Constellation Program and

    NASA Image and Video Library

    2007-11-09

    On Launch Pad 39B at NASA's Kennedy Space Center, workers measure the piling being pounded into the ground to help construct lightning towers for the Constellation Program and Ares/Orion launches. Pad B will be the site of the first Ares vehicle launch, including Ares I-X which is scheduled for April 2009.

  13. Video Games, Identity, and the Constellation of Information

    ERIC Educational Resources Information Center

    Martin, Crystle

    2012-01-01

    This article explores the identity of youth in relation to the information sources they choose in the constellation of information of video games, using the massively multiplayer online game "World of Warcraft" as an example. From this study, several identities are recognized that are combinations of the participants skill and level in the game,…

  14. Determination of Earth outgoing radiation using a constellation of satellites

    NASA Astrophysics Data System (ADS)

    Gristey, Jake; Chiu, Christine; Gurney, Robert; Han, Shin-Chan; Morcrette, Cyril

    2017-04-01

    The outgoing radiation fluxes at the top of the atmosphere, referred to as Earth outgoing radiation (EOR), constitute a vital component of the Earth's energy budget. This EOR exhibits strong diurnal signatures and is inherently connected to the rapidly evolving scene from which the radiation originates, so our ability to accurately monitor EOR with sufficient temporal resolution and spatial coverage is crucial for weather and climate studies. Despite vast improvements in satellite observations in recent decades, achieving these criteria remains challenging from current measurements. A technology revolution in small satellites and sensor miniaturisation has created a new and exciting opportunity for a novel, viable and sustainable observation strategy from a constellation of satellites, capable of providing both global coverage and high temporal resolution simultaneously. To explore the potential of a constellation approach for observing EOR we perform a series of theoretical simulation experiments. Using the results from these simulation experiments, we will demonstrate a baseline constellation configuration capable of accurately monitoring global EOR at unprecedented temporal resolution. We will also show whether it is possible to reveal synoptic scale, fast evolving phenomena by applying a deconvolution technique to the simulated measurements. The ability to observe and understand the relationship between these phenomena and changes in EOR is of fundamental importance in constraining future warming of our climate system.

  15. RapidEye constellation relative radiometric accuracy measurement using lunar images

    NASA Astrophysics Data System (ADS)

    Steyn, Joe; Tyc, George; Beckett, Keith; Hashida, Yoshi

    2009-09-01

    The RapidEye constellation includes five identical satellites in Low Earth Orbit (LEO). Each satellite has a 5-band (blue, green, red, red-edge and near infrared (NIR)) multispectral imager at 6.5m GSD. A three-axes attitude control system allows pointing the imager of each satellite at the Moon during lunations. It is therefore possible to image the Moon from near identical viewing geometry within a span of 80 minutes with each one of the imagers. Comparing the radiometrically corrected images obtained from each band and each satellite allows a near instantaneous relative radiometric accuracy measurement and determination of relative gain changes between the five imagers. A more traditional terrestrial vicarious radiometric calibration program has also been completed by MDA on RapidEye. The two components of this program provide for spatial radiometric calibration ensuring that detector-to-detector response remains flat, while a temporal radiometric calibration approach has accumulated images of specific dry dessert calibration sites. These images are used to measure the constellation relative radiometric response and make on-ground gain and offset adjustments in order to maintain the relative accuracy of the constellation within +/-2.5%. A quantitative comparison between the gain changes measured by the lunar method and the terrestrial temporal radiometric calibration method is performed and will be presented.

  16. Second BRITE-Constellation Science Conference: Small satellites—big science, Proceedings of the Polish Astronomical Society volume 5

    NASA Astrophysics Data System (ADS)

    Zwintz, Konstanze; Poretti, Ennio

    2017-09-01

    In 2016 the BRITE-Constellation mission had been operational for more than two years. At that time, several hundreds of bright stars of various types had been observed successfully in the two BRITE lters and astonishing new discoveries had been made. Therefore, the time was ripe to host the Second BRITE-Constellation Science Conference: Small satellites | big science" from August 22 to 26, 2016, in the beautiful Madonnensaal of the University of Innsbruck, Austria. With this conference, we brought together the scientic community interested in BRITE-Constellation, pro- vided an update on the status of the mission, presented and discussed latest scientic results, shared our experiences with the data, illustrated successful cooperations between professional and amateur ground-based observers and BRITE scientists, and explored new ideas for future BRITE-Constellation observations.

  17. 75 FR 30295 - Amendment of Class E Airspace; Hoquiam, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-01

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-1063; Airspace Docket No. 09-ANM-22] Amendment of Class E Airspace; Hoquiam, WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action will amend existing Class E...

  18. 78 FR 46258 - Drawbridge Operation Regulation Lake Washington, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... Operation Regulation Lake Washington, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of deviation from... that governs the Evergreen Point Floating Bridge (State Route 520 across Lake Washington) at Seattle... Route 520 across Lake Washington) remain closed to vessel traffic to facilitate safe passage of...

  19. Analysis and design of Cubesat constellation for the Mediterranean south costal monitoring against illegal immigration

    NASA Astrophysics Data System (ADS)

    Lazreg, Nissen; Ben Bahri, Omar; Besbes, Kamel

    2018-02-01

    Costal monitoring is focused on fast response to illegal immigration and illegal ship traffic. Especially, the illegal ship traffic has been present in media since April 2015, as the number of reported deaths of immigrants crossing the Mediterranean significantly increased. Satellite images provide a possibility to at least partially control both types of events. This paper defines the principal criteria to select the best satellite constellation architecture for maritime and coastal monitoring, filling the gaps of imagery techniques in term of real-time control. The primary purpose of a constellation is to obtain global measurement improving the temporal resolution. The small size and low-cost are the main factors, which make CubeSats ideal for use in constellations. We propose a constellation of 9 Cubesats distributed evenly in 3 different planes. This reduces the revisit time enhancing the coverage duration. In addition, it also allows observing fire, damage on building and similar disasters. In this analysis, the performance criteria were reported such as the revisit time, the vision duration and the area coverage.

  20. EOS Terra Terra Constellation Exit/Future Maneuver Plans Update

    NASA Technical Reports Server (NTRS)

    Mantziaras, Dimitrios

    2016-01-01

    This EOS Terra Constellation Exit/Future Maneuver Plans Update presentation will discuss brief history of Terra EOM work; lifetime fuel estimates; baseline vs. proposed plan origin; resultant exit orbit; baseline vs. proposed exit plan; long term orbit altitude; revised lifetime proposal and fallback options.

  1. Constructing lightning towers for the Constellation Program and

    NASA Image and Video Library

    2007-11-09

    On Launch Pad 39B at NASA's Kennedy Space Center, the crane crawler puts a piling into place to be pounded into the ground to help construct lightning towers for the Constellation Program and Ares/Orion launches. Pad B will be the site of the first Ares vehicle launch, including Ares I-X which is scheduled for April 2009.

  2. Constructing lightning towers for the Constellation Program and

    NASA Image and Video Library

    2007-11-09

    On Launch Pad 39B at NASA's Kennedy Space Center, the crane crawler lifts a piling into place to be pounded into the ground to help construct lightning towers for the Constellation Program and Ares/Orion launches. Pad B will be the site of the first Ares vehicle launch, including Ares I-X which is scheduled for April 2009.

  3. 75 FR 35968 - Safety Zone; Fireworks Display in Stevenson, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-24

    ...-AA00 Safety Zone; Fireworks Display in Stevenson, WA AGENCY: Coast Guard, DHS. ACTION: Temporary final... safety of the maritime public during the fireworks display and will do so by prohibiting all persons and... with fireworks displays on navigable waters. Such hazards include premature detonations, dangerous...

  4. 75 FR 37294 - Modification of Class E Airspace; Kelso, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... airspace at Kelso, WA, to accommodate aircraft using a new Area Navigation (RNAV) Global Positioning System... improve the safety and management of Instrument Flight Rules (IFR) operations at the airport. DATES: Effective date, 0901 UTC, September 23, 2010. The Director of the Federal Register approves this...

  5. [Study on malnutrition status among Wa ethnicity children and adolescents in Lingcang prefecture, Yunnan province].

    PubMed

    Yang, Yunjuan; Chang, Litao; Chen, Lu; Wei, Xijing

    2015-12-01

    To analyze the malnutrition status among children and adolescents of Wa ethnicity in Lincang prefecture, Yunnan province from 2005 to 2014, and to provide evidence for the improvement of the situation. From 2005 to 2014, children and adolescents aged 7 to 18, from 19 primary and secondary schools in Cangyuan county of Lincang prefecture, Yunnan province, were chosen, using the multistage-stratified-random cluster sampling method, to receive physic examination. WHO-2006 standard was used. Situation related to the rate of growth retardation and malnutrition among students was analyzed, from 2005 to 2014. Data was from the National Student Physical Health Research Project. From 2000 to 2014, trends on nutrition development among these students were also studied. The rates related to growth retardation among 7-18 years-old Wa boys in 2005, 2010 and 2014 were 45.61%, 52.36% and 35.85%, with the rates of thinness as 1.44%, 0.76% and 1.36% , respectively. Rates on malnutrition were 52.35% , 56.01% and 41.13% , respectively. Rates related to growth retardation among 7-18 years-old Wa girls were 42.03%, 47.41% and 33.06%, respectively, with rates of thinness as 0.91%, 0.68% and 0.83%, respectively. The rates on malnutrition were 46.13%, 49.77% and 35.56%, respectively. From year 2005 to 2014, spurt on height growth of boys and girls were among the 13-14 years-old and 9-10 years-old, respectively. Girls were 4 years earlier, entering the sudden increase in the peak age than boys. Sex difference on height among the 18 years-old Wa youngsters were 11.99, 9.34 and 11.38 cm in 2005, 2010 and 2014, respectively. Malnutrition status of retardation on growth among Wa children and adolescents remained quite serious.

  6. Mapping disease-related missense mutations in the immunoglobulin-like fold domain of lamin A/C reveals novel genotype-phenotype associations for laminopathies.

    PubMed

    Scharner, Juergen; Lu, Hui-Chun; Fraternali, Franca; Ellis, Juliet A; Zammit, Peter S

    2014-06-01

    Mutations in A-type nuclear lamins cause laminopathies. However, genotype-phenotype correlations using the 340 missense mutations within the LMNA gene are unclear: partially due to the limited availability of three-dimensional structure. The immunoglobulin (Ig)-like fold domain has been solved, and using bioinformatics tools (including Polyphen-2, Fold X, Parameter OPtimized Surfaces, and PocketPicker) we characterized 56 missense mutations for position, surface exposure, change in charge and effect on Ig-like fold stability. We find that 21 of the 27 mutations associated with a skeletal muscle phenotype are distributed throughout the Ig-like fold, are nonsurface exposed and predicted to disrupt overall stability of the Ig-like fold domain. Intriguingly, the remaining 6 mutations clustered, had higher surface exposure, and did not affect stability. The majority of 9 lipodystrophy or 10 premature aging syndrome mutations also did not disrupt Ig-like fold domain stability and were surface exposed and clustered in distinct regions that overlap predicted binding pockets. Although buried, the 10 cardiac mutations had no other consistent properties. Finally, most lipodystrophy and premature aging mutations resulted in a -1 net charge change, whereas skeletal muscle mutations caused no consistent net charge changes. Since premature aging, lipodystrophy and the subset of 6 skeletal muscle mutations cluster tightly in distinct, charged regions, they likely affect lamin A/C -protein/DNA/RNA interactions: providing a consistent genotype-phenotype relationship for mutations in this domain. Thus, this subgroup of skeletal muscle laminopathies that we term the 'Skeletal muscle cluster', may have a distinct pathological mechanism. These novel associations refine the ability to predict clinical features caused by certain LMNA missense mutations. © 2013 Wiley Periodicals, Inc.

  7. Strategy for Mitigating Collision Between Landsat-5 and the Afternoon Constellation

    NASA Technical Reports Server (NTRS)

    Levi, Joshua A.; Palmer, Eric J.

    2011-01-01

    The NASA Goddard Space Flight Center Earth Science Mission Operations project, the French space agency Centre National d tudes Spatiales, the Argentinian space agency Comisi n Nacional de Actividades Espaciales, and the United States Geological Survey all operate spacecraft in sun-synchronous frozen orbits. The orbits are planned to not place any of the spacecraft at risk of colliding with another. However, evolution of these orbits over time has com-promised the safe interaction between Landsat-5 and the Afternoon Constella-tion. This paper analyzes the interactions between the Landsat-5 spacecraft and the Afternoon Constellation members over a period of 6 years, describing the current risk and plan to mitigate collisions in the future.

  8. Coverage and control of constellations of elliptical inclined frozen lunar orbits

    NASA Technical Reports Server (NTRS)

    Ely, Todd A.

    2005-01-01

    A great deal of scientific interest exists regarding the permanently shadowed craters near the poles of the Moon where there may be frozen volatiles. These regions, particularly the Moon's South Pole, have been proposed for extensive robotic and human exploration. Unfortunately, they are typically not in view of Earth, and would require some form of communication relay to facilitate exploration via robotic and/or human missions. One solution for such a relay is a long-lived constellation of lunar telecommunication orbiters providing focused coverage at the pole of interest. Robust support requires this coverage to be continuous, redundant, and, in order to minimize costs, this constellation should consist of 3 satellites or fewer.

  9. Real-time Retrieving Atmospheric Parameters from Multi-GNSS Constellations

    NASA Astrophysics Data System (ADS)

    Li, X.; Zus, F.; Lu, C.; Dick, G.; Ge, M.; Wickert, J.; Schuh, H.

    2016-12-01

    The multi-constellation GNSS (e.g. GPS, GLONASS, Galileo, and BeiDou) bring great opportunities and challenges for real-time retrieval of atmospheric parameters for supporting numerical weather prediction (NWP) nowcasting or severe weather event monitoring. In this study, the observations from different GNSS are combined together for atmospheric parameter retrieving based on the real-time precise point positioning technique. The atmospheric parameters retrieved from multi-GNSS observations, including zenith total delay (ZTD), integrated water vapor (IWV), horizontal gradient (especially high-resolution gradient estimates) and slant total delay (STD), are carefully analyzed and evaluated by using the VLBI, radiosonde, water vapor radiometer and numerical weather model to independently validate the performance of individual GNSS and also demonstrate the benefits of multi-constellation GNSS for real-time atmospheric monitoring. Numerous results show that the multi-GNSS processing can provide real-time atmospheric products with higher accuracy, stronger reliability and better distribution, which would be beneficial for atmospheric sounding systems, especially for nowcasting of extreme weather.

  10. Autonomy Architectures for a Constellation of Spacecraft

    NASA Technical Reports Server (NTRS)

    Barrett, Anthony

    2000-01-01

    This paper describes three autonomy architectures for a system that continuously plans to control a fleet of spacecraft using collective mission goals instead of goals of command sequences for each spacecraft. A fleet of self-commanding spacecraft would autonomously coordinate itself to satisfy high level science and engineering goals in a changing partially-understood environment-making feasible the operation of tens of even a hundred spacecraft (such as for interferometer or magnetospheric constellation missions).

  11. Constellation design with geometric and probabilistic shaping

    NASA Astrophysics Data System (ADS)

    Zhang, Shaoliang; Yaman, Fatih

    2018-02-01

    A systematic study, including theory, simulation and experiments, is carried out to review the generalized pairwise optimization algorithm for designing optimized constellation. In order to verify its effectiveness, the algorithm is applied in three testing cases: 2-dimensional 8 quadrature amplitude modulation (QAM), 4-dimensional set-partitioning QAM, and probabilistic-shaped (PS) 32QAM. The results suggest that geometric shaping can work together with PS to further bridge the gap toward the Shannon limit.

  12. Satellite Constellation Optimization for Turkish Armed Forces

    DTIC Science & Technology

    2013-03-01

    capability. 29 III. OPTIMIZATION WITH STK A. ANALYSIS The goal was to minimize the number of satellites and then minimize the number of planes...www.oosa.unvienna.org/pdf/reports/ac105/AC105_1005E.pdf. Wertz, James R. and Larson, Wiley J. “Space Mission Analysis and Design (Third Edition).” Space...Systems Tool Kit software for simulation and analysis of several possible communications and remote sensing satellite constellations covering Turkish

  13. 78 FR 67027 - Drawbridge Operation Regulation; Lake Washington, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... at Seattle, WA. The deviation is necessary to accommodate vehicular traffic attending football games... bridge to remain in the closed position two hours before and two hours after each game. DATES: This... closed to vessel traffic to facilitate rapid movement of pre-game and post game football traffic...

  14. 77 FR 54805 - Revocation of Jet Route J-528; WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2012-0749; Airspace Docket No. 11-ANM-29] RIN 2120-AA66 Revocation of Jet Route J-528; WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action removes Jet Route J-528...

  15. Tabitha's One Teacher Rural School: Insights into the Arts through the Use of a Story Constellation

    ERIC Educational Resources Information Center

    Garvis, Susanne

    2011-01-01

    This paper presents a story constellation about a beginning teacher (who is also the principal) located in a one-teacher school in an isolated community in Queensland, Australia. The constellation documents the teacher's self-efficacy for teaching the arts (music, dance, drama, visual arts and media). Tabitha, the participant, shares insights…

  16. Design and Analysis of on-Orbit Servicing Architectures for the Global Positioning System Constellation

    DTIC Science & Technology

    1999-03-01

    expressed in this thesis are those of the author and do not reflect the official policy or position of the Department of Defense or the U.S...a satellite constellation through a policy of launching a new satellite at the first on-orbit failure. Increasing satellite design life is a common...alternatives consisted of the current constellation with the addition of various servicing architectures. We assumed no radical shift in GPS management policy

  17. 33 CFR 165.1321 - Security Zone; Protection of Military Cargo, Captain of the Port Zone Puget Sound, WA.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Military Cargo, Captain of the Port Zone Puget Sound, WA. 165.1321 Section 165.1321 Navigation and... the Port Zone Puget Sound, WA. (a) Notice of enforcement or suspension of enforcement. The Captain of the Port Puget Sound will enforce the security zones established by this section only upon notice...

  18. 33 CFR 165.1321 - Security Zone; Protection of Military Cargo, Captain of the Port Zone Puget Sound, WA.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Military Cargo, Captain of the Port Zone Puget Sound, WA. 165.1321 Section 165.1321 Navigation and... the Port Zone Puget Sound, WA. (a) Notice of enforcement or suspension of enforcement. The Captain of the Port Puget Sound will enforce the security zones established by this section only upon notice...

  19. The Constellation-X Mission: Science Prospects and Technology Challenges

    NASA Technical Reports Server (NTRS)

    Petre, Robert

    2007-01-01

    This talk will describe the Constellation-X mission. It will present the key scientific goals, relating to strong gravity, dark energy, ultra-dense matter and cosmic structure. The mission configuration will be described. Emphasis will be placed on the design and anticipated implementation of the X-ray mirror system.

  20. Constructing lightning towers for the Constellation Program and

    NASA Image and Video Library

    2007-11-09

    On Launch Pad 39B at NASA's Kennedy Space Center, the crane crawler lifts a piling off a truck. The piling will be pounded into the ground to help construct lightning towers for the Constellation Program and Ares/Orion launches. Pad B will be the site of the first Ares vehicle launch, including Ares I-X which is scheduled for April 2009.

  1. Water Accounting Plus (WA+) - a water accounting procedure for complex river basins based on satellite measurements

    NASA Astrophysics Data System (ADS)

    Karimi, P.; Bastiaanssen, W. G. M.; Molden, D.

    2012-11-01

    Coping with the issue of water scarcity and growing competition for water among different sectors requires proper water management strategies and decision processes. A pre-requisite is a clear understanding of the basin hydrological processes, manageable and unmanageable water flows, the interaction with land use and opportunities to mitigate the negative effects and increase the benefits of water depletion on society. Currently, water professionals do not have a common framework that links hydrological flows to user groups of water and their benefits. The absence of a standard hydrological and water management summary is causing confusion and wrong decisions. The non-availability of water flow data is one of the underpinning reasons for not having operational water accounting systems for river basins in place. In this paper we introduce Water Accounting Plus (WA+), which is a new framework designed to provide explicit spatial information on water depletion and net withdrawal processes in complex river basins. The influence of land use on the water cycle is described explicitly by defining land use groups with common characteristics. Analogous to financial accounting, WA+ presents four sheets including (i) a resource base sheet, (ii) a consumption sheet, (iii) a productivity sheet, and (iv) a withdrawal sheet. Every sheet encompasses a set of indicators that summarize the overall water resources situation. The impact of external (e.g. climate change) and internal influences (e.g. infrastructure building) can be estimated by studying the changes in these WA+ indicators. Satellite measurements can be used for 3 out of the 4 sheets, but is not a precondition for implementing WA+ framework. Data from hydrological models and water allocation models can also be used as inputs to WA+.

  2. Modified empirical Solar Radiation Pressure model for IRNSS constellation

    NASA Astrophysics Data System (ADS)

    Rajaiah, K.; Manamohan, K.; Nirmala, S.; Ratnakara, S. C.

    2017-11-01

    Navigation with Indian Constellation (NAVIC) also known as Indian Regional Navigation Satellite System (IRNSS) is India's regional navigation system designed to provide position accuracy better than 20 m over India and the region extending to 1500 km around India. The reduced dynamic precise orbit estimation is utilized to determine the orbit broadcast parameters for IRNSS constellation. The estimation is mainly affected by the parameterization of dynamic models especially Solar Radiation Pressure (SRP) model which is a non-gravitational force depending on shape and attitude dynamics of the spacecraft. An empirical nine parameter solar radiation pressure model is developed for IRNSS constellation, using two-way range measurements from IRNSS C-band ranging system. The paper addresses the development of modified SRP empirical model for IRNSS (IRNSS SRP Empirical Model, ISEM). The performance of the ISEM was assessed based on overlap consistency, long term prediction, Satellite Laser Ranging (SLR) residuals and compared with ECOM9, ECOM5 and new-ECOM9 models developed by Center for Orbit Determination in Europe (CODE). For IRNSS Geostationary Earth Orbit (GEO) and Inclined Geosynchronous Orbit (IGSO) satellites, ISEM has shown promising results with overlap RMS error better than 5.3 m and 3.5 m respectively. Long term orbit prediction using numerical integration has improved with error better than 80%, 26% and 7.8% in comparison to ECOM9, ECOM5 and new-ECOM9 respectively. Further, SLR based orbit determination with ISEM shows 70%, 47% and 39% improvement over 10 days orbit prediction in comparison to ECOM9, ECOM5 and new-ECOM9 respectively and also highlights the importance of wide baseline tracking network.

  3. First detection of multiple knockdown resistance (kdr)-like mutations in voltage-gated sodium channel using three new genotyping methods in Anopheles sinensis from Guangxi Province, China.

    PubMed

    Tan, Wei L; Li, Chun X; Wang, Zhong M; Liu, Mei D; Dong, Yan D; Feng, Xiang Y; Wu, Zhi M; Guo, Xiao X; Xing, Dan; Zhang, Ying M; Wang, Zhong C; Zhao, Tong Y

    2012-09-01

    To investigate knockdown resistance (kdr)-like mutations associated with pyrethroid resistance in Anopheles sinensis (Wiedemann, 1828), from Guangxi province, southwest China, a segment of a sodium channel gene was sequenced and genotyped using three new genotyping assays. Direct sequencing revealed the presence of TTG-to-TCG and TG-to-TTT mutations at allele position L1014, which led to L1014S and L1014F substitutions in a few individual and two novel substitutions of N1013S and L1014W in two DNA templates. A low frequency of the kdr allele mostly in the heterozygous state of L1014S and L1014F was observed in this mosquito population. In this study, the genotyping of An. sinensis using three polymerase chain reaction-based methods generated consistent results, which agreed with the results of DNA sequencing. In total, 52 mosquitoes were genotyped using a direct sequencing assay. The number of mosquitoes and their genotypes were as follows: L/L = 24, L/S = 19, L/F = 8, and F/W = 1. The allelic frequency of L1014, 1014S, and 1014F were 72, 18, and 9%, respectively.

  4. 33 CFR 165.1302 - Bangor Naval Submarine Base, Bangor, WA.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Bangor Naval Submarine Base... Bangor Naval Submarine Base, Bangor, WA. (a) Location. The following is a security zone: The waters of... States Naval vessels. (ii) Vessels that are performing work at Naval Submarine Base Bangor pursuant to a...

  5. 33 CFR 165.1302 - Bangor Naval Submarine Base, Bangor, WA.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Bangor Naval Submarine Base... Bangor Naval Submarine Base, Bangor, WA. (a) Location. The following is a security zone: The waters of... States Naval vessels. (ii) Vessels that are performing work at Naval Submarine Base Bangor pursuant to a...

  6. 33 CFR 165.1302 - Bangor Naval Submarine Base, Bangor, WA.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Bangor Naval Submarine Base... Bangor Naval Submarine Base, Bangor, WA. (a) Location. The following is a security zone: The waters of... States Naval vessels. (ii) Vessels that are performing work at Naval Submarine Base Bangor pursuant to a...

  7. 76 FR 3922 - Willapa National Wildlife Refuge, Pacific County, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R1-R-2010-N083; 1265-0000-10137-S3] Willapa National Wildlife Refuge, Pacific County, WA AGENCY: Fish and Wildlife Service, Interior. ACTION...; request for comments. SUMMARY: We, the U.S. Fish and Wildlife Service (Service), announce the availability...

  8. 75 FR 34154 - Ridgefield National Wildlife Refuge, Clark County, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R1-R-2010-N001; 1265-0000-10137-S3] Ridgefield National Wildlife Refuge, Clark County, WA AGENCY: Fish and Wildlife Service, Interior. ACTION... comments. SUMMARY: We, the U.S. Fish and Wildlife Service (Service), announce the availability of our draft...

  9. 33 CFR 165.1302 - Bangor Naval Submarine Base, Bangor, WA.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Bangor Naval Submarine Base... Bangor Naval Submarine Base, Bangor, WA. (a) Location. The following is a security zone: The waters of... States Naval vessels. (ii) Vessels that are performing work at Naval Submarine Base Bangor pursuant to a...

  10. 2014_11_05_uss_constellation

    NASA Image and Video Library

    2014-11-10

    NASA’s Operation IceBridge collected some rare images on a flight out of Punta Arenas, Chile on Nov. 5, 2014, on a science flight over western Antarctica dubbed Ferrigno-Alison-Abbott 01. Following a routine calibration pass over Punta Arenas airport, the NASA DC-8 overflew the USS Constellation which is being towed for demolition after 53 yeas of service. The crew then snapped a few shots of a calving front of the Antarctic ice sheet. This particular flight plan was designed to collect data on changes in ice elevation along the coast near the Ferrigno and Alison ice streams, on the Abbot Ice Shelf, and grounded ice along the Eights Coast.

  11. CubeSat constellations for disaster management in remote areas

    NASA Astrophysics Data System (ADS)

    Santilli, Giancarlo; Vendittozzi, Cristian; Cappelletti, Chantal; Battistini, Simone; Gessini, Paolo

    2018-04-01

    In recent years, CubeSats have considerably extended their range of possible applications, from a low cost means to train students and young researchers in space related activities up to possible complementary solutions to larger missions. Increasingly popular, whereas CubeSats are still not a solution for all types of missions, they offer the possibility of performing ambitious scientific experiments. Especially worth considering is the possibility of performing Distributed Space Missions, in which CubeSat systems can be used to increase observation sampling rates and resolutions, as well as to perform tasks that a single satellite is unable to handle. The cost of access to space for traditional Earth Observation (EO) missions is still quite high. Efficient architecture design would allow reducing mission costs by employing CubeSat systems, while maintaining a level of performance that, for some applications, could be close to that provided by larger platforms, and decreasing the time needed to design and deploy a fully functional constellation. For these reasons many countries, including developing nations, agencies and organizations are looking to CubeSat platforms to access space cheaply with, potentially, tens of remote sensing satellites. During disaster management, real-time, fast and continuous information broadcast is a fundamental requirement. In this sense, a constellation of small satellites can considerably decrease the revisit time (defined as the time elapsed between two consecutive observations of the same point on Earth by a satellite) over remote areas, by increasing the number of spacecraft properly distributed in orbit. This allows collecting as much data as possible for the use by Disaster Management Centers. This paper describes the characteristics of a constellation of CubeSats built to enable access over the most remote regions of Brazil, supporting an integrated system for mitigating environmental disasters in an attempt to prevent the

  12. The Availability of Space Service for Inter-Satellite Links in Navigation Constellations

    PubMed Central

    Tang, Yinyin; Wang, Yueke; Chen, Jianyun

    2016-01-01

    Global navigation satellite systems (GNSS) are widely used in low Earth orbit (LEO) satellite navigation; however, their availability is poor for users in medium Earth orbits (MEO), and high Earth orbits (HEO). With the increasing demand for navigation from MEO and HEO users, the inadequate coverage of GNSS has emerged. Inter-satellite links (ISLs) are used for ranging and communication between navigation satellites and can also serve space users that are outside the navigation constellation. This paper aims to summarize their application method and analyze their service performance. The mathematical model of visibility is proposed and then the availability of time division ISLs is analyzed based on global grid points. The BeiDou navigation constellation is used as an example for numerical simulation. Simulation results show that the availability can be enhanced by scheduling more satellites and larger beams, while the presence of more users lowers the availability. The availability of navigation signals will be strengthened when combined with the signals from the ISLs. ISLs can improve the space service volume (SSV) of navigation constellations, and are therefore a promising method for navigation in MEO/HEO spacecraft. PMID:27548181

  13. Secure optical generalized filter bank multi-carrier system based on cubic constellation masked method.

    PubMed

    Zhang, Lijia; Liu, Bo; Xin, Xiangjun

    2015-06-15

    A secure optical generalized filter bank multi-carrier (GFBMC) system with carrier-less amplitude-phase (CAP) modulation is proposed in this Letter. The security is realized through cubic constellation-masked method. Large key space and more flexibility masking can be obtained by cubic constellation masking aligning with the filter bank. An experiment of 18 Gb/s encrypted GFBMC/CAP system with 25-km single-mode fiber transmission is performed to demonstrate the feasibility of the proposed method.

  14. Norovirus genotypes causing gastroenteritis outbreaks in Finland 1998-2002.

    PubMed

    Maunula, L; Von Bonsdorff, C-H

    2005-11-01

    Outbreak investigation methods for enteric viruses were improved in 1990s when gene amplification techniques were established in viral laboratories. The objective of the study was to determine the causative agents for Finnish viral gastroenteritis outbreaks. Our aim was also to further characterise the norovirus strains, reveal the temporal occurrence of norovirus (NV) genotypes and to study some epidemiological aspects concerning the outbreaks. A total of 416 Finnish viral gastroenteritis outbreaks that occurred during 5 years (1998-2002), excluding those among hospitalised children, were investigated for enteric viruses. Stool samples were screened by electron microscopy as well as analyzed by specific noro- and astrovirus RT-PCR tests. Amplicon sequence analysis was used to find out norovirus genotypes. Noroviruses caused 252 (60.6%) of the outbreaks; other viruses, astro- or rotavirus, caused four epidemics. Norovirus epidemics occurred in all kinds of settings, most often in hospitals (30.6%) and in restaurants and canteens (14.3%). Both NV genogroups were found every year, but NV GGII outbreaks always outnumbered those of GGI. All but one outbreak at hospitals and nursing homes were of genotype GII. Polymerase sequence analysis revealed a variety of NV genotypes; six GI and at least eight GII genotypes. The GI.3 Birmingham-like and GII.4 Bristol-like genotype appeared every year, whereas the other types were circulating for shorter periods or sporadically. During the study period the genotypes GII.4 (Bristol), GII.1 (Hawaii), an emerging genotype GIIb, and a new variant of GII.4 predominated in that order. Indication for rapid genetic changes in the genotype GII.4 was also noticed. Noroviruses were the most prevalent causative agents in the outbreaks. Many NV genotypes were circulating, and a shift in the predominant genotypes was evident between epidemic seasons.

  15. The genotype-phenotype map of an evolving digital organism.

    PubMed

    Fortuna, Miguel A; Zaman, Luis; Ofria, Charles; Wagner, Andreas

    2017-02-01

    To understand how evolving systems bring forth novel and useful phenotypes, it is essential to understand the relationship between genotypic and phenotypic change. Artificial evolving systems can help us understand whether the genotype-phenotype maps of natural evolving systems are highly unusual, and it may help create evolvable artificial systems. Here we characterize the genotype-phenotype map of digital organisms in Avida, a platform for digital evolution. We consider digital organisms from a vast space of 10141 genotypes (instruction sequences), which can form 512 different phenotypes. These phenotypes are distinguished by different Boolean logic functions they can compute, as well as by the complexity of these functions. We observe several properties with parallels in natural systems, such as connected genotype networks and asymmetric phenotypic transitions. The likely common cause is robustness to genotypic change. We describe an intriguing tension between phenotypic complexity and evolvability that may have implications for biological evolution. On the one hand, genotypic change is more likely to yield novel phenotypes in more complex organisms. On the other hand, the total number of novel phenotypes reachable through genotypic change is highest for organisms with simple phenotypes. Artificial evolving systems can help us study aspects of biological evolvability that are not accessible in vastly more complex natural systems. They can also help identify properties, such as robustness, that are required for both human-designed artificial systems and synthetic biological systems to be evolvable.

  16. The genotype-phenotype map of an evolving digital organism

    PubMed Central

    Zaman, Luis; Wagner, Andreas

    2017-01-01

    To understand how evolving systems bring forth novel and useful phenotypes, it is essential to understand the relationship between genotypic and phenotypic change. Artificial evolving systems can help us understand whether the genotype-phenotype maps of natural evolving systems are highly unusual, and it may help create evolvable artificial systems. Here we characterize the genotype-phenotype map of digital organisms in Avida, a platform for digital evolution. We consider digital organisms from a vast space of 10141 genotypes (instruction sequences), which can form 512 different phenotypes. These phenotypes are distinguished by different Boolean logic functions they can compute, as well as by the complexity of these functions. We observe several properties with parallels in natural systems, such as connected genotype networks and asymmetric phenotypic transitions. The likely common cause is robustness to genotypic change. We describe an intriguing tension between phenotypic complexity and evolvability that may have implications for biological evolution. On the one hand, genotypic change is more likely to yield novel phenotypes in more complex organisms. On the other hand, the total number of novel phenotypes reachable through genotypic change is highest for organisms with simple phenotypes. Artificial evolving systems can help us study aspects of biological evolvability that are not accessible in vastly more complex natural systems. They can also help identify properties, such as robustness, that are required for both human-designed artificial systems and synthetic biological systems to be evolvable. PMID:28241039

  17. First Crewed Flight: Rationale, Considerations and Challenges from the Constellation Experience

    NASA Technical Reports Server (NTRS)

    Noriega, Carlos; Arceneaux, William; Williams, Jeffrey A.; Rhatigan, Jennifer L.

    2011-01-01

    NASA's Constellation Program has made the most progress in a generation towards building an integrated human-rated spacecraft and launch vehicle. During that development, it became clear that NASA's human-rating requirements lacked the specificity necessary to defend a program plan, particularly human-rating test flight plans, from severe budget challenges. This paper addresses the progress Constellation achieved, problems encountered in clarifying and defending a human-rating certification plan, and discusses key considerations for those who find themselves in similar straits with future human-rated spacecraft and vehicles. We assert, and support with space flight data, that NASA's current human-rating requirements do not adequately address "unknown-unknowns", or the unexpected things the hardware can reveal to the designer during test.

  18. Leo Satellite Communication through a LEO Constellation using TCP/IP Over ATM

    NASA Technical Reports Server (NTRS)

    Foore, Lawrence R.; Konangi, Vijay K.; Wallett, Thomas M.

    1999-01-01

    The simulated performance characteristics for communication between a terrestrial client and a Low Earth Orbit (LEO) satellite server are presented. The client and server nodes consist of a Transmission Control Protocol /Internet Protocol (TCP/IP) over ATM configuration. The ATM cells from the client or the server are transmitted to a gateway, packaged with some header information and transferred to a commercial LEO satellite constellation. These cells are then routed through the constellation to a gateway on the globe that allows the client/server communication to take place. Unspecified Bit Rate (UBR) is specified as the quality of service (QoS). Various data rates are considered.

  19. WASTE MINIZATION OPPORTUNITY ASSESSMENT: NAVAL UNDERSEA WARFARE ENGINEERING STATION - KEYPORT, WA

    EPA Science Inventory

    This report describes the application of EPA's waste minimization assessment procedures to a torpedo maintenance facility at the Naval Undersea Warfare Engineering Station, Keyport, WA. he assessment focused on the Mark 48 shop and the Mark 46 shop. hese shops service the Mark 48...

  20. Global communication using a constellation of low earth meridian orbits

    NASA Astrophysics Data System (ADS)

    Oli, P. V. S.; Nagarajan, N.; Rayan, H. R.

    1993-07-01

    The concept of 'meridian orbits' is briefly reviewed. It is shown that, if a satellite in the meridian orbit makes an odd number of revolutions per day, then the satellite passes over the same set of meridians twice a day. Satellites in such orbits pass over the same portion of the sky twice a day and every day. This enables a user to adopt a programmed mode of tracking, thereby avoiding a computational facility for orbit prediction, look angle generation, and auto tracking. A constellation of 38 or more satellites placed in a 1200 km altitude circular orbit is favorable for global communications due to various factors. It is shown that appropriate phasing in right ascension of the ascending node and mean anomaly results in a constellation, wherein each satellite appears over the user's horizon one satellite after another. Visibility and coverage plots are provided to verify the continuous coverage.

  1. 78 FR 22413 - Amendment of Class E Airspace; Omak, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-16

    ... upward from 4,500 feet Mean Sea Level (MSL). This improves the safety and management of Instrument Flight... airspace extending upward from 4,500 feet MSL be rewritten for clarity. With the exception of editorial... 700 feet above the surface and 1,200 feet above the surface at Omak Airport, Omak, WA. The Omak NDB...

  2. Radiometric and geometric assessment of data from the RapidEye constellation of satellites

    USGS Publications Warehouse

    Chander, Gyanesh; Haque, Md. Obaidul; Sampath, Aparajithan; Brunn, A.; Trosset, G.; Hoffmann, D.; Roloff, S.; Thiele, M.; Anderson, C.

    2013-01-01

    To monitor land surface processes over a wide range of temporal and spatial scales, it is critical to have coordinated observations of the Earth's surface using imagery acquired from multiple spaceborne imaging sensors. The RapidEye (RE) satellite constellation acquires high-resolution satellite images covering the entire globe within a very short period of time by sensors identical in construction and cross-calibrated to each other. To evaluate the RE high-resolution Multi-spectral Imager (MSI) sensor capabilities, a cross-comparison between the RE constellation of sensors was performed first using image statistics based on large common areas observed over pseudo-invariant calibration sites (PICS) by the sensors and, second, by comparing the on-orbit radiometric calibration temporal trending over a large number of calibration sites. For any spectral band, the individual responses measured by the five satellites of the RE constellation were found to differ <2–3% from the average constellation response depending on the method used for evaluation. Geometric assessment was also performed to study the positional accuracy and relative band-to-band (B2B) alignment of the image data sets. The position accuracy was assessed by comparing the RE imagery against high-resolution aerial imagery, while the B2B characterization was performed by registering each band against every other band to ensure that the proper band alignment is provided for an image product. The B2B results indicate that the internal alignments of these five RE bands are in agreement, with bands typically registered to within 0.25 pixels of each other or better.

  3. Development of arrays of position-sensitive microcalorimeters for Constellation-X

    NASA Astrophysics Data System (ADS)

    Smith, Stephen J.; Bandler, Simon R.; Brekosky, Regis P.; Brown, Ari-D.; Chervenak, James A.; Eckart, Megan E.; Figueroa-Feliciano, Enectali; Finkbeiner, Fred M.; Kelley, Richard L.; Kilbourne, Caroline A.; Porter, F. Scott; Sadleir, John E.

    2008-07-01

    We are developing arrays of position-sensitive transition-edge sensor (PoST) X-ray detectors for future astronomy missions such as NASA's Constellation-X. The PoST consists of multiple absorbers thermally coupled to one or more transition-edge sensor (TES). Each absorber element has a different thermal coupling to the TES. This results in a distribution of different pulse shapes and enables position discrimination between the absorber elements. PoST's are motivated by the desire to achieve the largest possible focal plane area with the fewest number of readout channels and are ideally suited to increasing the Constellation-X focal plane area, without comprising on spatial sampling. Optimizing the performance of PoST's requires careful design of key parameters such as the thermal conductances between the absorbers, TES and the heat sink, as well as the absorber heat capacities. Our new generation of PoST's utilizes technology successfully developed on high resolution (~ 2.5 eV) single pixels arrays of Mo/Au TESs, also under development for Constellation-X. This includes noise mitigation features on the TES and low resistivity electroplated absorbers. We report on the first experimental results from new one-channel, four-pixel, PoST's or 'Hydras', consisting of composite Au/Bi absorbers. We have achieved full-width-at-half-maximum energy resolution of between 5-6 eV on all four Hydra pixels with an exponential decay time constant of 620 μs. Straightforward position discrimination by means of rise time is also demonstrated.

  4. Influenza A Viruses of Swine (IAV-S) in Vietnam from 2010 to 2015: Multiple Introductions of A(H1N1)pdm09 Viruses into the Pig Population and Diversifying Genetic Constellations of Enzootic IAV-S.

    PubMed

    Takemae, Nobuhiro; Harada, Michiyo; Nguyen, Phuong Thanh; Nguyen, Tung; Nguyen, Tien Ngoc; To, Thanh Long; Nguyen, Tho Dang; Pham, Vu Phong; Le, Vu Tri; Do, Hoa Thi; Vo, Hung Van; Le, Quang Vinh Tin; Tran, Tan Minh; Nguyen, Thanh Duy; Thai, Phuong Duy; Nguyen, Dang Hoang; Le, Anh Quynh Thi; Nguyen, Diep Thi; Uchida, Yuko; Saito, Takehiko

    2017-01-01

    Active surveillance of influenza A viruses of swine (IAV-S) involving 262 farms and 10 slaughterhouses in seven provinces in northern and southern Vietnam from 2010 to 2015 yielded 388 isolates from 32 farms; these viruses were classified into H1N1, H1N2, and H3N2 subtypes. Whole-genome sequencing followed by phylogenetic analysis revealed that the isolates represented 15 genotypes, according to the genetic constellation of the eight segments. All of the H1N1 viruses were entirely A(H1N1)pdm09 viruses, whereas all of the H1N2 and H3N2 viruses were reassortants among 5 distinct ancestral viruses: H1 and H3 triple-reassortant (TR) IAV-S that originated from North American pre-2009 human seasonal H1, human seasonal H3N2, and A(H1N1)pdm09 viruses. Notably, 93% of the reassortant IAV-S retained M genes that were derived from A(H1N1)pdm09, suggesting some advantage in terms of their host adaptation. Bayesian Markov chain Monte Carlo analysis revealed that multiple introductions of A(H1N1)pdm09 and TR IAV-S into the Vietnamese pig population have driven the genetic diversity of currently circulating Vietnamese IAV-S. In addition, our results indicate that a reassortant IAV-S with human-like H3 and N2 genes and an A(H1N1)pdm09 origin M gene likely caused a human case in Ho Chi Minh City in 2010. Our current findings indicate that human-to-pig transmission as well as cocirculation of different IAV-S have contributed to diversifying the gene constellations of IAV-S in Vietnam. This comprehensive genetic characterization of 388 influenza A viruses of swine (IAV-S) isolated through active surveillance of Vietnamese pig farms from 2010 through 2015 provides molecular epidemiological insight into the genetic diversification of IAV-S in Vietnam after the emergence of A(H1N1)pdm09 viruses. Multiple reassortments among A(H1N1)pdm09 viruses and enzootic IAV-S yielded 14 genotypes, 9 of which carried novel gene combinations. The reassortants that carried M genes derived from A(H1N1

  5. Influenza A Viruses of Swine (IAV-S) in Vietnam from 2010 to 2015: Multiple Introductions of A(H1N1)pdm09 Viruses into the Pig Population and Diversifying Genetic Constellations of Enzootic IAV-S

    PubMed Central

    Takemae, Nobuhiro; Harada, Michiyo; Nguyen, Phuong Thanh; Nguyen, Tung; Nguyen, Tien Ngoc; To, Thanh Long; Nguyen, Tho Dang; Pham, Vu Phong; Le, Vu Tri; Do, Hoa Thi; Vo, Hung Van; Le, Quang Vinh Tin; Tran, Tan Minh; Nguyen, Thanh Duy; Thai, Phuong Duy; Nguyen, Dang Hoang; Le, Anh Quynh Thi; Nguyen, Diep Thi; Uchida, Yuko

    2016-01-01

    ABSTRACT Active surveillance of influenza A viruses of swine (IAV-S) involving 262 farms and 10 slaughterhouses in seven provinces in northern and southern Vietnam from 2010 to 2015 yielded 388 isolates from 32 farms; these viruses were classified into H1N1, H1N2, and H3N2 subtypes. Whole-genome sequencing followed by phylogenetic analysis revealed that the isolates represented 15 genotypes, according to the genetic constellation of the eight segments. All of the H1N1 viruses were entirely A(H1N1)pdm09 viruses, whereas all of the H1N2 and H3N2 viruses were reassortants among 5 distinct ancestral viruses: H1 and H3 triple-reassortant (TR) IAV-S that originated from North American pre-2009 human seasonal H1, human seasonal H3N2, and A(H1N1)pdm09 viruses. Notably, 93% of the reassortant IAV-S retained M genes that were derived from A(H1N1)pdm09, suggesting some advantage in terms of their host adaptation. Bayesian Markov chain Monte Carlo analysis revealed that multiple introductions of A(H1N1)pdm09 and TR IAV-S into the Vietnamese pig population have driven the genetic diversity of currently circulating Vietnamese IAV-S. In addition, our results indicate that a reassortant IAV-S with human-like H3 and N2 genes and an A(H1N1)pdm09 origin M gene likely caused a human case in Ho Chi Minh City in 2010. Our current findings indicate that human-to-pig transmission as well as cocirculation of different IAV-S have contributed to diversifying the gene constellations of IAV-S in Vietnam. IMPORTANCE This comprehensive genetic characterization of 388 influenza A viruses of swine (IAV-S) isolated through active surveillance of Vietnamese pig farms from 2010 through 2015 provides molecular epidemiological insight into the genetic diversification of IAV-S in Vietnam after the emergence of A(H1N1)pdm09 viruses. Multiple reassortments among A(H1N1)pdm09 viruses and enzootic IAV-S yielded 14 genotypes, 9 of which carried novel gene combinations. The reassortants that carried M genes

  6. Influence of developmental stage and genotype on liver mRNA levels among wild, domesticated, and hybrid rainbow trout (Oncorhynchus mykiss).

    PubMed

    White, Samantha L; Sakhrani, Dionne; Danzmann, Roy G; Devlin, Robert H

    2013-10-02

    Release of domesticated strains of fish into nature may pose a threat to wild populations with respect to their evolved genetic structure and fitness. Understanding alterations that have occurred in both physiology and genetics as a consequence of domestication can assist in evaluating the risks posed by introgression of domesticated genomes into wild genetic backgrounds, however the molecular causes of these consequences are currently poorly defined. The present study has examined levels of mRNA in fast-growing pure domesticated (D), slow-growing age-matched pure wild (Wa), slow-growing size-matched pure wild (Ws), and first generation hybrid cross (W/D) rainbow trout (Oncorhynchus mykiss) to investigate the influence of genotype (domesticated vs. wild, and their interactions in hybrids) and developmental stage (age- or size-matched animals) on genetic responses (i.e. dominant vs. recessive) and specific physiological pathways. Highly significant differences in mRNA levels were found between domesticated and wild-type rainbow trout genotypes (321 mRNAs), with many mRNAs in the wild-domesticated hybrid progeny showing intermediate levels. Differences were also found between age-matched and size-matched wild-type trout groups (64 mRNAs), with unique mRNA differences for each of the wild-type groups when compared to domesticated trout (Wa: 114 mRNAs, Ws: 88 mRNAs), illustrating an influence of fish developmental stage affecting findings when used as comparator groups to other genotypes. Analysis of differentially expressed mRNAs (found for both wild-type trout to domesticated comparisons) among the genotypes indicates that 34.8% are regulated consistent with an additive genetic model, whereas 39.1% and 26.1% show a recessive or dominant mode of regulation, respectively. These molecular data are largely consistent with phenotypic data (growth and behavioural assessments) assessed in domesticated and wild trout strains. The present molecular data are concordant with

  7. Applications of Precipitation Feature Databases from GPM core and constellation Satellites

    NASA Astrophysics Data System (ADS)

    Liu, C.

    2017-12-01

    Using the observations from Global Precipitation Mission (GPM) core and constellation satellites, global precipitation was quantitatively described from the perspective of precipitation systems and their properties. This presentation will introduce the development of precipitation feature databases, and several scientific questions that have been tackled using this database, including the topics of global snow precipitation, extreme intensive convection, hail storms, extreme precipitation, and microphysical properties derived with dual frequency radars at the top of convective cores. As more and more observations of constellation satellites become available, it is anticipated that the precipitation feature approach will help to address a large variety of scientific questions in the future. For anyone who is interested, all the current precipitation feature databases are freely open to public at: http://atmos.tamucc.edu/trmm/.

  8. ISHM Implementation for Constellation Systems

    NASA Technical Reports Server (NTRS)

    Figueroa, Fernando; Holland, Randy; Schmalzel, John; Duncavage, Dan; Crocker, Alan; Alena, Rick

    2006-01-01

    Integrated System Health Management (ISHM) is a capability that focuses on determining the condition (health) of every element in a complex System (detect anomalies, diagnose causes, prognosis of future anomalies), and provide data, information, and knowledge (DIaK) "not just data" to control systems for safe and effective operation. This capability is currently done by large teams of people, primarily from ground, but needs to be embedded on-board systems to a higher degree to enable NASA's new Exploration Mission (long term travel and stay in space), while increasing safety and decreasing life cycle costs of systems (vehicles; platforms; bases or outposts; and ground test, launch, and processing operations). This viewgraph presentation reviews the use of ISHM for the Constellation system.

  9. 76 FR 35363 - Proposed Amendment to Class B Airspace; Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ...: This action proposes to modify Class B airspace in Seattle, WA to contain aircraft conducting... surrounding airports with high density air traffic operations by providing an area, in which all aircraft are... in higher airport arrival acceptance rates during IFR minimums, but requires aircraft to be...

  10. 75 FR 24789 - Modification of Jet Route J-3; Spokane, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-06

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2010-0008; Airspace Docket No. 09-ANM-21] Modification of Jet Route J-3; Spokane, WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Jet Route J-3 by...

  11. 77 FR 23120 - National Maritime Week Tugboat Races, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ... Maritime Week Tugboat Races in Elliott Bay, WA from 12 p.m. through 4:30 p.m. on May 12, 2012. This action... associated with these types of races which includes large wakes. During the enforcement period, no person or... Guard Patrol Commander. DATES: The regulations in 33 CFR 100.1306 will be enforced from 12 p.m. through...

  12. Flying the ST-5 Constellation with "Plug and Play" Autonomy Components and the GMSEC Bus

    NASA Technical Reports Server (NTRS)

    Shendock, Bob; Witt, Ken; Stanley, Jason; Mandl, Dan; Coyle, Steve

    2006-01-01

    The Space Technology 5 (ST5) Project, part of NASA's New Millennium Program, will consist of a constellation of three micro-satellites. This viewgraph document presents the components that will allow it to operate in an autonomous mode. The ST-5 constellation will use the GSFC Mission Services Evolution Center (GMSEC) architecture to enable cost effective model based operations. The ST-5 mission will demonstrate several principles of self managing software components.

  13. 78 FR 40960 - Drawbridge Operation Regulation; Lake Washington Ship Canal at Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-09

    ..., WA. The deviation is necessary to accommodate the ``See Jane Run Women's Half Marathon.'' This... necessary to accommodate the ``See Jane Run Women's Half Marathon''. This deviation allows the bridges to...

  14. Evolutionary analysis of rubella viruses in mainland China during 2010-2012: endemic circulation of genotype 1E and introductions of genotype 2B.

    PubMed

    Zhu, Zhen; Rivailler, Pierre; Abernathy, Emily; Cui, Aili; Zhang, Yan; Mao, Naiyin; Xu, Songtao; Zhou, Shujie; Lei, Yue; Wang, Yan; Zheng, Huanying; He, Jilan; Chen, Ying; Li, Chongshan; Bo, Fang; Zhao, Chunfang; Chen, Meng; Lu, Peishan; Li, Fangcai; Gu, Suyi; Gao, Hui; Guo, Yu; Chen, Hui; Feng, Daxing; Wang, Shuang; Tang, Xiaomin; Lei, Yake; Feng, Yan; Deng, Lili; Gong, Tian; Fan, Lixia; Xu, Wenbo; Icenogle, Joseph

    2015-01-23

    Rubella remains a significant burden in mainland China. In this report, 667 viruses collected in 24 of 31 provinces of mainland China during 2010-2012 were sequenced and analyzed, significantly extending previous reports on limited numbers of viruses collected before 2010. Only viruses of genotypes 1E and 2B were found. Genotype 1E viruses were found in all 24 provinces. Genotype 1E viruses were likely introduced into mainland China around 1997 and endemic transmission of primarily one lineage became established. Viruses reported here from 2010-2012 are largely in a single cluster within this lineage. Genotype 2B viruses were rarely detected in China prior to 2010. This report documents a previously undetected 2B lineage, which likely became endemic in eastern provinces of China between 2010 and 2012. Bayesian analyses were performed to estimate the evolutionary rates and dates of appearance of the genotype 1E and 2B viral linages in China. A skyline plot of viral population diversity did not provide evidence of reduction of diversity as a result of vaccination, but should be useful as a baseline for such reductions as vaccination programs for rubella become widespread in mainland China.

  15. Group A Rotaviruses in Chinese Bats: Genetic Composition, Serology, and Evidence for Bat-to-Human Transmission and Reassortment.

    PubMed

    He, Biao; Huang, Xiaohong; Zhang, Fuqiang; Tan, Weilong; Matthijnssens, Jelle; Qin, Shaomin; Xu, Lin; Zhao, Zihan; Yang, Ling'en; Wang, Quanxi; Hu, Tingsong; Bao, Xiaolei; Wu, Jianmin; Tu, Changchun

    2017-06-15

    Bats are natural reservoirs for many pathogenic viruses, and increasing evidence supports the notion that bats can also harbor group A rotaviruses (RVAs), important causative agents of diarrhea in children and young animals. Currently, 8 RVA strains possessing completely novel genotype constellations or genotypes possibly originating from other mammals have been identified from African and Chinese bats. However, all the data were mainly based on detection of RVA RNA, present only during acute infections, which does not permit assessment of the true exposure of a bat population to RVA. To systematically investigate the genetic diversity of RVAs, 547 bat anal swabs or gut samples along with 448 bat sera were collected from five South Chinese provinces. Specific reverse transcription-PCR (RT-PCR) screening found four RVA strains. Strain GLRL1 possessed a completely novel genotype constellation, whereas the other three possessed a constellation consistent with the MSLH14-like genotype, a newly characterized group of viruses widely prevalent in Chinese insectivorous bats. Among the latter, strain LZHP2 provided strong evidence of cross-species transmission of RVAs from bats to humans, whereas strains YSSK5 and BSTM70 were likely reassortants between typical MSLH14-like RVAs and human RVAs. RVA-specific antibodies were detected in 10.7% (48/448) of bat sera by an indirect immunofluorescence assay (IIFA). Bats in Guangxi and Yunnan had a higher RVA-specific antibody prevalence than those from Fujian and Zhejiang provinces. These observations provide evidence for cross-species transmission of MSLH14-like bat RVAs to humans, highlighting the impact of bats as reservoirs of RVAs on public health. IMPORTANCE Bat viruses, such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), Ebola, Hendra, and Nipah viruses, are important pathogens causing outbreaks of severe emerging infectious diseases. However, little is known about bat viruses capable

  16. Diversity and Relationships of Cocirculating Modern Human Rotaviruses Revealed Using Large-Scale Comparative Genomics

    PubMed Central

    McKell, Allison O.; Rippinger, Christine M.; McAllen, John K.; Akopov, Asmik; Kirkness, Ewen F.; Payne, Daniel C.; Edwards, Kathryn M.; Chappell, James D.; Patton, John T.

    2012-01-01

    Group A rotaviruses (RVs) are 11-segmented, double-stranded RNA viruses and are primary causes of gastroenteritis in young children. Despite their medical relevance, the genetic diversity of modern human RVs is poorly understood, and the impact of vaccine use on circulating strains remains unknown. In this study, we report the complete genome sequence analysis of 58 RVs isolated from children with severe diarrhea and/or vomiting at Vanderbilt University Medical Center (VUMC) in Nashville, TN, during the years spanning community vaccine implementation (2005 to 2009). The RVs analyzed include 36 G1P[8], 18 G3P[8], and 4 G12P[8] Wa-like genogroup 1 strains with VP6-VP1-VP2-VP3-NSP1-NSP2-NSP3-NSP4-NSP5/6 genotype constellations of I1-R1-C1-M1-A1-N1-T1-E1-H1. By constructing phylogenetic trees, we identified 2 to 5 subgenotype alleles for each gene. The results show evidence of intragenogroup gene reassortment among the cocirculating strains. However, several isolates from different seasons maintained identical allele constellations, consistent with the notion that certain RV clades persisted in the community. By comparing the genes of VUMC RVs to those of other archival and contemporary RV strains for which sequences are available, we defined phylogenetic lineages and verified that the diversity of the strains analyzed in this study reflects that seen in other regions of the world. Importantly, the VP4 and VP7 proteins encoded by VUMC RVs and other contemporary strains show amino acid changes in or near neutralization domains, which might reflect antigenic drift of the virus. Thus, this large-scale, comparative genomic study of modern human RVs provides significant insight into how this pathogen evolves during its spread in the community. PMID:22696651

  17. A satellite constellation optimization for a regional GNSS remote sensing mission

    NASA Astrophysics Data System (ADS)

    Gavili Kilaneh, Narin; Mashhadi Hossainali, Masoud

    2017-04-01

    Due to the recent advances in the Global Navigation Satellite System Remote sensing (GNSS¬R) applications, optimization of a satellite orbit to investigate the Earth's properties seems significant. The comparison of the GNSS direct and reflected signals received by a Low Earth Orbit (LEO) satellite introduces a new technique to remotely sense the Earth. Several GNSS¬R missions including Cyclone Global Navigation Satellite System (CYGNSS) have been proposed for different applications such as the ocean wind speed and height monitoring. The geometric optimization of the satellite orbit before starting the mission is a key step for every space mission. Since satellite constellation design varies depending on the application, we have focused on the required geometric criteria for oceanography applications in a specified region. Here, the total number of specular points, their spatial distribution and the accuracy of their position are assumed to be sufficient for oceanography applications. Gleason's method is used to determine the position of specular points. We considered the 2-D lattice and 3-D lattice theory of flower constellation to survey whether a circular orbit or an elliptical one is suitable to improve the solution. Genetic algorithm is implemented to solve the problem. To check the visibility condition between the LEO and GPS satellites, the satellite initial state is propagated by a variable step size numerical integration method. Constellation orbit parameters achieved by optimization provide a better resolution and precession for the specular points in the study area of this research.

  18. The Magnetospheric Multiscale Constellation

    NASA Technical Reports Server (NTRS)

    Tooley, C. R.; Black, R. K.; Robertson, B. P.; Stone, J. M.; Pope, S. E.; Davis, G. T.

    2015-01-01

    The Magnetospheric Multiscale (MMS) mission is the fourth mission of the Solar Terrestrial Probe (STP) program of the National Aeronautics and Space Administration (NASA). The MMS mission was launched on March 12, 2015. The MMS mission consists of four identically instrumented spin-stabilized observatories which are flown in formation to perform the first definitive study of magnetic reconnection in space. The MMS mission was presented with numerous technical challenges, including the simultaneous construction and launch of four identical large spacecraft with 100 instruments total, stringent electromagnetic cleanliness requirements, closed-loop precision maneuvering and pointing of spinning flexible spacecraft, on-board GPS based orbit determination far above the GPS constellation, and a flight dynamics design that enables formation flying with separation distances as small as 10 km. This paper describes the overall mission design and presents an overview of the design, testing, and early on-orbit operation of the spacecraft systems and instrument suite.

  19. Attribute and topology based change detection in a constellation of previously detected objects

    DOEpatents

    Paglieroni, David W.; Beer, Reginald N.

    2016-01-19

    A system that applies attribute and topology based change detection to networks of objects that were detected on previous scans of a structure, roadway, or area of interest. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, size, elongation, orientation, etc. The topology of the network of previously detected objects is maintained in a constellation database that stores attributes of previously detected objects and implicitly captures the geometrical structure of the network. A change detection system detects change by comparing the attributes and topology of new objects detected on the latest scan to the constellation database of previously detected objects.

  20. Development of arrays of position-sensitive microcalorimeters for Constellation-X

    NASA Technical Reports Server (NTRS)

    Smith, S. J.; Bandler, S. R.; Brekosky, R. P.; Brown, A.-D.; Chervenak, J. A.; Eckart, M. E.; Finkbeiner, F. M.; Iyomoto, N.; Kelley, R. L.; Kolbourne, C. A.; hide

    2008-01-01

    We are developing arrays of position-sensitive transition-edge sensor (POST) X-ray detectors for future astronomy missions such as NASA's Constellation-X. The POST consists of multiple absorbers thermally coupled to one or more transition-edge sensor (TES). Each absorber element has a different thermal coupling to the TES. This results in a distribution of different pulse shapes and enables position discrimination between the absorber elements. POST'S are motivated by the desire to achieve the largest possible focal plane area with the fewest number of readout channels and are ideally suited to increasing the Constellation-X focal plane area, without comprising on spatial sampling. Optimizing the performance of POST'S requires careful design of key parameters such as the thermal conductances between the absorbers, TES and the heat sink. as well as the absorber heat capacities. Using recently developed signal processing algorithms we have investigated the trade-off between position-sensitivity, energy resolution and pulse decay time. based on different device design parameters for PoST's. Our new generation of PoST's utilize technology successfully developed on high resolution (approximately 2.5eV) single pixels arrays of Mo/Au TESs. also under development for Constellation-X. This includes noise mitigation features on the TES and low resistivity electroplated absorbers. We report on the first experimental results from these new one and two-channel PoST"s, consisting of all Au and composite Au/Bi absorbers, which are designed to achieve an energy resolution of < 10 eV. coupled with count-rates of 100's per pixel per second and position sensitivity over the energy range 0.3-10 keV.

  1. Prevalence of GBS serotype III and identification of a ST 17-like genotype from neonates with invasive diseases in Guangzhou, China.

    PubMed

    Liu, Junyan; Xu, Ruiru; Zhong, Huamin; Zhong, Yukui; Xie, Yongqiang; Li, Lin; Li, Bing; Chen, Dingqiang; Xu, Zhenbo

    2018-05-03

    The aim of this study is to understand the surveillance of Streptococcus agalactiae (GBS) serotype and genotype which help developing specific vaccine for GBS infection. The GBS serotype was determined by strep-B-Latex rapid agglutination method and multiplex PCR assay based on the differences among serotypes. Alleles and multilocus sequence types (MLST) were determined using the GBS MLST Web site. Four GBS serotypes (Ia, Ib, III, and V) were identified, with serotype III which was intimately associated with purulent meningitis and sepsis, as the dominance. In EOD cases, sepsis and pneumonia showed dominance, but purulent meningitis was dominant in LOD cases. Also, a new ST-17 like type which might be a clone derive from ST-17 and emerge among neonatal disease cases was identified. The prevalence of GBS serotype and genotype and their relation with GBS diseases guide the development of capsular polysaccharide vaccine. Copyright © 2018. Published by Elsevier Ltd.

  2. Structural and functional analysis of the finished genome of the recently isolated toxic Anabaena sp. WA102.

    PubMed

    Brown, Nathan M; Mueller, Ryan S; Shepardson, Jonathan W; Landry, Zachary C; Morré, Jeffrey T; Maier, Claudia S; Hardy, F Joan; Dreher, Theo W

    2016-06-13

    Very few closed genomes of the cyanobacteria that commonly produce toxic blooms in lakes and reservoirs are available, limiting our understanding of the properties of these organisms. A new anatoxin-a-producing member of the Nostocaceae, Anabaena sp. WA102, was isolated from a freshwater lake in Washington State, USA, in 2013 and maintained in non-axenic culture. The Anabaena sp. WA102 5.7 Mbp genome assembly has been closed with long-read, single-molecule sequencing and separately a draft genome assembly has been produced with short-read sequencing technology. The closed and draft genome assemblies are compared, showing a correlation between long repeats in the genome and the many gaps in the short-read assembly. Anabaena sp. WA102 encodes anatoxin-a biosynthetic genes, as does its close relative Anabaena sp. AL93 (also introduced in this study). These strains are distinguished by differences in the genes for light-harvesting phycobilins, with Anabaena sp. AL93 possessing a phycoerythrocyanin operon. Biologically relevant structural variants in the Anabaena sp. WA102 genome were detected only by long-read sequencing: a tandem triplication of the anaBCD promoter region in the anatoxin-a synthase gene cluster (not triplicated in Anabaena sp. AL93) and a 5-kbp deletion variant present in two-thirds of the population. The genome has a large number of mobile elements (160). Strikingly, there was no synteny with the genome of its nearest fully assembled relative, Anabaena sp. 90. Structural and functional genome analyses indicate that Anabaena sp. WA102 has a flexible genome. Genome closure, which can be readily achieved with long-read sequencing, reveals large scale (e.g., gene order) and local structural features that should be considered in understanding genome evolution and function.

  3. Different Duck Species Infected Intramuscularly with Duck-Origin Genotype IX APMV-1 Show Discrepant Mortality and Indicate Another Fatal Genotype APMV-1 to Ducks.

    PubMed

    Fu, Guanghua; Cheng, Longfei; Fu, Qiuling; Qi, Baomin; Chen, Cuiteng; Shi, Shaohua; Chen, Hongmei; Wan, Chunhe; Liu, Rongchang; Huang, Yu

    2017-03-01

    Isolations of genotype IX (gIX) avian paramyxovirus type 1 (APMV-1) from various bird species have been more common recently, with isolates showing variable pathogenicity in different species of poultry. Here we sequenced the genome of a Muscovy duck origin gIX virus strain XBT14 and characterized the virulence and pathogenicity of this isolate in chickens and ducks. The genome sequence of strain XBT14 is 15,192 nt in length, containing multiple basic amino acids at the fusion protein cleavage site. The XBT14 strain shared 91.6%-91.9% nucleotide identities with early-genotype viruses (such as genotype III and IV) and shared 85.3%-85.9% nucleotide homologies with later genotype viruses (such as genotype VII). Pathogenicity tests showed that strain XBT14 could cause death in different duck breeds with a mortality rate of 44.4% in Muscovy duck, 25.9% in Sheldrake, and 11.1% in Cherry Valley duck, respectively. Similar mortality discrepancies were also observed in different ducks when infected with chicken-origin gIX virus strain F48E8. These results indicate that XBT14-like velogenic gIX APMV-1 (such as XBT14, F48E8, and GD09-2) could cause fatal infection in duck, and genotype IX is another genotype velogenic to duck as well as genotype VII. Accompanied by genetic differences in the vaccine strains or dominant strains prevailing in poultry, the virulent XBT14-like gIX viruses might become potentially endemic strains in poultry in the future.

  4. A new class of weight and WA systems of the Kravchenko-Kaiser functions

    NASA Astrophysics Data System (ADS)

    Kravchenko, V. F.; Pustovoit, V. I.; Churikov, D. V.

    2014-05-01

    A new class of weight and WA-systems of the Kravchenko-Kaiser functions which showed its efficiency in various physical applications is proposed and substantiated. This publication consists of three parts. In the first the Kravchenko-Kaiser weight functions are constructed on basis of the theory of atomic functions (AFs) and the Kaiser windows for the first time. In the second part new constructions of analytic WA-systems of the Kravchenko-Kaiser functions are costructed. In the third part their applications to problems of weight averaging of the difference frequency signals are considered. The numerical experiment and the physical analysis of the results for concrete physical models confirmed their efficiency. This class of functions can find wide physical applications in problems of digital signal processing, restoration of images, radar, radiometry, radio astronomy, remote sensing, etc.

  5. Massive pulsating stars observed by BRITE-Constellation. I. The triple system β Centauri (Agena)

    NASA Astrophysics Data System (ADS)

    Pigulski, A.; Cugier, H.; Popowicz, A.; Kuschnig, R.; Moffat, A. F. J.; Rucinski, S. M.; Schwarzenberg-Czerny, A.; Weiss, W. W.; Handler, G.; Wade, G. A.; Koudelka, O.; Matthews, J. M.; Mochnacki, St.; Orleański, P.; Pablo, H.; Ramiaramanantsoa, T.; Whittaker, G.; Zocłońska, E.; Zwintz, K.

    2016-04-01

    Context. Asteroseismology of massive pulsating stars of β Cep and SPB types can help us to uncover the internal structure of massive stars and understand certain physical phenomena that are taking place in their interiors. We study β Centauri (Agena), a triple system with two massive fast-rotating early B-type components which show p- and g-mode pulsations; the system's secondary is also known to have a measurable magnetic field. Aims: This paper aims to precisely determine the masses and detect pulsation modes in the two massive components of β Cen with BRITE-Constellation photometry. In addition, seismic models for the components are considered and the effects of fast rotation are discussed. This is done to test the limitations of seismic modeling for this very difficult case. Methods: A simultaneous fit of visual and spectroscopic orbits is used to self-consistently derive the orbital parameters, and subsequently the masses, of the components. Time-series analysis of BRITE-Constellation data is used to detect pulsation modes and derive their frequencies, amplitudes, phases, and rates of frequency change. Theoretically-predicted frequencies are calculated for the appropriate evolutionary models and their stability is checked. The effects of rotational splitting and coupling are also presented. Results: The derived masses of the two massive components are equal to 12.02 ± 0.13 and 10.58 ± 0.18 M⊙. The parameters of the wider, A-B system, presently approaching periastron passage, are constrained. Analysis of the combined blue- and red-filter BRITE-Constellation photometric data of the system revealed the presence of 19 periodic terms, of which eight are likely g modes, nine are p modes, and the remaining two are combination terms. It cannot be excluded that one or two low-frequency terms are rotational frequencies. It is possible that both components of β Cen are β Cep/SPB hybrids. An attempt to use the apparent changes of frequency to distinguish which

  6. Cell Line Controls for the Genotyping of a Spectrum of Human Single Nucleotide Polymorphisms in the Clinical Laboratory.

    PubMed

    Kimbacher, Christine; Paar, Christian; Freystetter, Andrea; Berg, Joerg

    2018-05-01

    Genotyping for clinically important single nucleotide polymorphisms (SNPs) is performed by many clinical routine laboratories. To support testing, quality controls and reference materials are needed. Those may be derived from residual patient samples, left over samples of external quality assurance schemes, plasmid DNA or DNA from cell lines. DNAs from cell lines are commutable and available in large amounts. DNA from 38 cell lines were examined for suitability as controls in 11 SNP assays that are frequently used in a clinical routine laboratory: FV (1691G>A), FII (20210G>A), PAI-1 4G/5G polymorphism, MTHFR (677C>T, 1298A>C), HFE (H63D, S65C, C282Y), APOE (E2, E3, E4), LPH (-13910C>T), UGT1A1 (*28, *36, *37), TPMT (*2, *3A, *3B, *3C), VKORC1 (-1639G>A, 1173C>T), CYP2C9 (*2, *3, *5). Genotyping was performed by real-time PCR with melting curve analysis and confirmed by bi-directional sequencing. We find an almost complete spectrum of genotypic constellations within these 38 cell lines. About 12 cell lines appear sufficient as genotypic controls for the 11 SNP assays by covering almost all of the genotypes. However, hetero- and homozygous genotypes for FII and the alleles TPMT*2, UGT1A1*37 and CYP2C9*5 were not detected in any of the cell lines. DNA from most of the examined cell lines appear suitable as quality controls for these SNP assays in the laboratory routine, as to the implementation of those assays or to prepare samples for quality assurance schemes. Our study may serve as a pilot to further characterize these cell lines to arrive at the status of reference materials.

  7. Surface Landing Site Weather Analysis for NASA's Constellation Program

    NASA Technical Reports Server (NTRS)

    Altino, Karen M.; Burns, K. L.

    2008-01-01

    Weather information is an important asset for NASA's Constellation Program in developing the next generation space transportation system to fly to the International Space Station, the Moon and, eventually, to Mars. Weather conditions can affect vehicle safety and performance during multiple mission phases ranging from pre-launch ground processing of the Ares vehicles to landing and recovery operations, including all potential abort scenarios. Meteorological analysis is art important contributor, not only to the development and verification of system design requirements but also to mission planning and active ground operations. Of particular interest are the surface weather conditions at both nominal and abort landing sites for the manned Orion capsule. Weather parameters such as wind, rain, and fog all play critical roles in the safe landing of the vehicle and subsequent crew and vehicle recovery. The Marshall Space Flight Center (MSFC) Natural Environments Branch has been tasked by the Constellation Program with defining the natural environments at potential landing zones. This paper wiI1 describe the methodology used for data collection and quality control, detail the types of analyses performed, and provide a sample of the results that cab be obtained.

  8. Symbolics of the constellations of sagittarius and centaurus in russian traditional culture

    NASA Astrophysics Data System (ADS)

    Bagdasarov, R.

    2001-12-01

    Centaurus falls into the category of 'imaginary animals'. The Russian tradition used not only the symbol Sgr (a result of its acquaintance with the circle of Zodiac), but also the symbol Cen, which fact, as we shall demonstrate, is an evidence of certain mythological-astronomical conceptions. Both the constellations Sagittarius (Sgr) and Centaurus (Cen) are usually represented as versions of the picture of a fantastic being, a Centaur, shaped as man from head to waist, and as an animal, mostly, a horse, from waist down. 'Centaurus' (from the Greek word kev (or kevw)) for 'kill' and o, for 'bull') means 'bull killer', and is probably related to the opposition of the zodiacal constellations Taurus and Sagittarius. When the latter begins to rise on to the night sky, the former disappears completely from view. Sagittarius is represented at ancient monuments related to astronomy as a centaur holding a bow and pointing at certain stars. The constellation of Centaurus is also symbolised by a centaur, but holding not a bow, but a staff or a spear in one hand and an 'animal of sacrifice' in the other (Higinus, Astronomica, III, 37, 1; Chernetsov, 1975, Figure 1). The attributes stand for the Peliases Spear (The Mithological Dictionary, 1991), depicted in astrological maps as The Spear of Centaurus1, The Wolf (Lupus), the Panther or the Beast (Flammarion, 1994).

  9. Electric Propulsion System for Constellation Deployment and Orbit Control of Minisats

    NASA Astrophysics Data System (ADS)

    Bianco, P.; de Rocco, L.; Lovera, M.

    1999-09-01

    The late technology developments and the demand for low-cost space missions have raised the interest in small satellites and in their potential use as parts of satellite formations as well as building units of satellite constellations. Formation flying of small satellites can be used to bring in-orbit spares for failed payloads on larger satellites as well as to replace large satellites at all by flying the mission on more small satellites, each carrying a single payload. Small satellites can be used in constellations for scientific missions (e.g. remote sensing) as well as for commercial purposes (e.g. data relay). Yet, "small satellite" doesn't necessarily mean "cheap satellite": cost reduction must be enforced into the space mission design since the very beginning of it, at system level. This usually implies seeking for trade-offs on most expensive system items for a small sat. Among these, we surely have the launch and the onboard propulsion system for orbital manoeuvres and station keeping: the stricter the requirements, the higher the costs. And, when dealing with satellite constellations or formations, orbital requirements can be quite challenging. The system designer is faced with the dilemma on whether to buy a relatively expensive dedicated launch or to have a highly cost-impactive autonomous onboard propulsion system that should perform orbit transfers as well. The present paper, which is an up-to-date version of the one presented at IAF-99, introduces a system based on FEEP (Field Emission Electric Propulsion) technology, featuring low thrust plug-on propulsion units. Thanks to the self-contained concept of FEEP thrusters and to the plug-on feature of the whole system, a very low cost-impactive onboard propulsion system can be implemented in order to serve for both orbital manoeuvres (constellation / formation deployment, orbit rising) and orbit maintenance (drag compensation, station keeping relative to other satellites). Most convenient strategies to

  10. 78 FR 25005 - Proposed Establishment of Class E Airspace; Port Townsend, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-29

    ... Jefferson County International Airport, Port Townsend, WA. Controlled airspace is necessary to accommodate... procedures at Jefferson County International Airport. The FAA is proposing this action to enhance the safety and management of aircraft operations at the airport. DATES: Comments must be received on or before...

  11. Walz configures the Amateur Radio (HAM) WA3 Antenna Assembly, Expedition Four

    NASA Image and Video Library

    2002-01-12

    ISS004-E-5930 (January 2002) --- Astronaut Carl E. Walz, Expedition Four flight engineer, works with the Amateur Radio (HAM) WA3 Antenna Assembly in the Zvezda Service Module on the International Space Station (ISS). The image was taken with a digital still camera.

  12. 75 FR 5703 - Proposed Modification of Jet Route J-3; Spokane, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2010-0008; Airspace Docket No. 09-ANM-21] Proposed Modification of Jet Route J-3; Spokane, WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This...

  13. Mt Pamola, the Electromagnetic Field, EMF, Thunderbird, Mothman and Environmental Monitoring Signals Via the Southern Constellation Phoenix As Detectable In Potato Cave, Acton, MA.

    NASA Astrophysics Data System (ADS)

    Pecora, Andrea S.; Pawa Matagamon, Sagamo

    2004-03-01

    Just below the peak of Mt Pamola in ME, at the juncture with the Knife Edge, downwardly arcing segments of Earths EMF, are manifested by a faint lotus-blossom-blue, neon-like glow at 3 pm some sunny afternoons. Similarly hued glows, and horizontal but variable-arced segmented trajectories, are somewhat periodically detectable under certain conditions in chambers at Acton, MA. These phenomena curiously have the filled-in profile that precisely matches the outline of the southern constellation Phoenix, which is never visible above the nighttime horizon locally. The stick-figure representation of the constellation Canis Major can also be detected in a chamber at Americas Stonehenge, two hours before it has arisen, at certain times. The sequence of phenomena visible at Acton correctly correlates with eclipses and other alignments of our solar system. Phoenix, a.k.a. Thunderbird and Mothman, is detectable elsewhere in MA.

  14. Representativeness of Tuberculosis Genotyping Surveillance in the United States, 2009-2010.

    PubMed

    Shak, Emma B; France, Anne Marie; Cowan, Lauren; Starks, Angela M; Grant, Juliana

    2015-01-01

    Genotyping of Mycobacterium tuberculosis isolates contributes to tuberculosis (TB) control through detection of possible outbreaks. However, 20% of U.S. cases do not have an isolate for testing, and 10% of cases with isolates do not have a genotype reported. TB outbreaks in populations with incomplete genotyping data might be missed by genotyping-based outbreak detection. Therefore, we assessed the representativeness of TB genotyping data by comparing characteristics of cases reported during January 1, 2009-December 31, 2010, that had a genotype result with those cases that did not. Of 22,476 cases, 14,922 (66%) had a genotype result. Cases without genotype results were more likely to be patients <19 years of age, with unknown HIV status, of female sex, U.S.-born, and with no recent history of homelessness or substance abuse. Although cases with a genotype result are largely representative of all reported U.S. TB cases, outbreak detection methods that rely solely on genotyping data may underestimate TB transmission among certain groups.

  15. The Base 32 Method: An Improved Method for Coding Sibling Constellations.

    ERIC Educational Resources Information Center

    Perfetti, Lawrence J. Carpenter

    1990-01-01

    Offers new sibling constellation coding method (Base 32) for genograms using binary and base 32 numbers that saves considerable microcomputer memory. Points out that new method will result in greater ability to store and analyze larger amounts of family data. (Author/CM)

  16. Sequencing and phylogenetic analysis of the coding region of six common rotavirus strains: evidence for intragenogroup reassortment among co-circulating G1P[8] and G2P[4] strains from the United States.

    PubMed

    Bányai, K; Mijatovic-Rustempasic, S; Hull, J J; Esona, M D; Freeman, M M; Frace, A M; Bowen, M D; Gentsch, J R

    2011-03-01

    The segmented genome of rotaviruses provides an opportunity for rotavirus strains to generate a large genetic diversity through reassortment; however, this mechanism is considered to play little role in the generation of mosaic gene constellations between Wa-like and DS-1-like strains in genes other than the neutralization antigens. A pilot study was undertaken to analyze these two epidemiologically important strains at the genomic level in order to (i) identify intergenogroup reassortment and (ii) to make available additional reference genome sequences of G1P[8] and G2P[4] for future genomics analyses. The full or nearly complete coding region of all 11 genes for 3 G1P[8] (LB2719, LB2758, and LB2771) and 3 G2P[4] (LB2744, LB2764, and LB2772) strains isolated from children hospitalized with severe diarrhea in Long Beach, California, where these strains were circulating at comparable rates during 2005-2006 are described in this study. Based on the full-genome classification system, all G1P[8] strains had a conserved genomic constellation: G1-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-E1-H1 and were mostly identical to the few Wa-like strains whose genome sequences have already been determined. Similarly, the genome sequences of the 3 G2P[4] strains were highly conserved: G2-P[4]-I2-R2-C2-M2-A2-N2-T2-E2-E2-H2 and displayed an overall lesser genetic divergence with reference DS-1-like strains. While intergenogroup reassortment was not seen between the G1P[8] and G2P[4] strains studied here, evidence for intragenogroup reassortment events was identified. Similar studies in the post-rotavirus genomic era will help uncover whether intergenogroup reassortment affecting the backbone genes could play a significant role in any potential vaccine breakthrough events by evading immunity of vaccinated children. Copyright © 2011 Wiley-Liss, Inc.

  17. Development of Constellation's Launch Control System

    NASA Technical Reports Server (NTRS)

    Lougheed, Kirk D.; Peaden, Cary J.

    2010-01-01

    The paper focuses on the National Aeronautics and Space Administration (NASA) Constellation Program's Launch Control System (LCS) development effort at Kennedy Space Center (KSC). It provides a brief history of some preceding efforts to provide launch control and ground processing systems for other NASA programs, and some lessons learned from those experiences. It then provides high level descriptions of the LCS mission, objectives, organization, architecture, and progress. It discusses some of our development tenets, including our use of standards based design and use of off-the-shelf products whenever possible, incremental development cycles, and highly reliable, available, and supportable enterprise class system servers. It concludes with some new lessons learned and our plans for the future.

  18. Cubesat Constellation Design for Air Traffic Monitoring

    NASA Technical Reports Server (NTRS)

    Nag, Sreeja; Rios, Joseph Lucio; Gerhardt, David; Pham, Camvu

    2015-01-01

    Suitably equipped global and local air traffic can be tracked. The tracking information may then be used for control from ground-based stations by receiving the Automatic Dependent Surveillance-Broadcast (ADS-B) signal. The ADS-B signal, emitted from the aircraft's Mode-S transponder, is currently tracked by terrestrial based receivers but not over remote oceans or sparsely populated regions such as Alaska or the Pacific Ocean. Lack of real-time aircraft time/location information in remote areas significantly hinders optimal planning and control because bigger "safety bubbles" (lateral and vertical separation) are required around the aircraft until they reach radar-controlled airspace. Moreover, it presents a search-and-rescue bottleneck. Aircraft in distress, e.g. Air France AF449 that crashed in 2009, take days to be located or cannot be located at all, e.g. Malaysia Airlines MH370 in 2014. In this paper, we describe a tool for designing a constellation of small satellites which demonstrates, through high-fidelity modeling based on simulated air traffic data, the value of space-based ADS-B monitoring and provides recommendations for cost-efficient deployment of a constellation of small satellites to increase safety and situational awareness in the currently poorly-served surveillance area of Alaska. Air traffic data has been obtained from the Future ATM Concepts Evaluation Tool (FACET), developed at NASA Ames Research Center, simulated over the Alaskan airspace over a period of one day. The simulation is driven by MATLAB with satellites propagated and coverage calculated using AGI's Satellite ToolKit(STK10).

  19. Onufrienko holds the Amateur Radio (HAM) WA3 Antenna Assembly, Expedition Four

    NASA Image and Video Library

    2002-01-12

    ISS004-E-5931 (January 2002) --- Cosmonaut Yury I. Onufrienko, Expedition Four mission commander representing Rosaviakosmos, works with the Amateur Radio (HAM) WA3 Antenna Assembly in the Zvezda Service Module on the International Space Station (ISS). The image was taken with a digital still camera.

  20. Individual Differences in L2 Acquisition of Japanese Particles "WA" and "GA"

    ERIC Educational Resources Information Center

    Mori, Sachiho

    2008-01-01

    Although the L2 acquisition studies of Japanese particles "WA" and "GA" were investigated by many researchers (Sakamoto, 2000), they completely ignored learners' individual differences. Indeed, learners' individualities are important factors for the L2 learning (Lightbrown & Spada, 1999). Thus, this research explored whether learners' individual…

  1. Equal-Curvature X-ray Telescope Designs for Constellation-X Mission

    NASA Technical Reports Server (NTRS)

    Saha, Timo T.; Content, David A.; Zhang, William W.

    2003-01-01

    We study grazing incidence Equal-Curvature telescope designs for the Constellation-X mission. These telescopes have nearly spherical axial surfaces. The telescopes are designed so that the axial curvature is the same on the primary and secondary. The optical performance of these telescopes is for all practical purposes identical to the equivalent Wolter telescopes.

  2. 75 FR 57167 - Safety Zone; CLS Fall Championship Hydroplane Race, Lake Sammamish, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-20

    ... waters of Lake Sammamish, WA for the Composite Laminate Specialties (CLS) Fall Championship Hydroplane... Delegation No. 0170.1 0 2. Add Sec. 165.T13-162 to read as follows: Sec. 165.T13-162 Safety Zone; Composite...

  3. CK-MM and ACE genotypes and physiological prediction of the creatine kinase response to exercise.

    PubMed

    Heled, Yuval; Bloom, Michael S; Wu, T John; Stephens, Quiona; Deuster, Patricia A

    2007-08-01

    Exertional rhabdomyolysis (ERB) is a syndrome of severe skeletal muscle breakdown. Blood levels of creatine kinase (CK) are widely used as a marker to reflect muscle breakdown. Some individuals exhibit extreme increases in blood CK after exercise and have been characterized as high responders (HR), but no clinical definition of HR exists and reasons for the HR phenomenon are not understood. This study investigated possible associations between the magnitude of the CK response to exercise and polymorphisms of two genes: muscle-specific creatine kinase (CK-MM) NcoI and angiotensin-converting enzyme (ACE) I/D. An exercise test for defining HR was also investigated. Participants (n = 88) underwent an exercise test that included stepping up and down two stairs for 5 min followed by 15 squats while wearing a backpack weighted at 30% of their body weight. CK levels were measured before, immediately after, and 48 and 72 h after the test. Nine participants (10.2%) were defined as HR. Participants with the CK-MM NcoI AA genotype had a sixfold higher risk of being HR compared with GG and AG genotypes (P = 0.031). No significant differences were found for the ACE I/D polymorphism. Percent body fat was an independent predictor of being a HR. We conclude that the CK-MM AA genotype and percent body fat may be part of the constellation of mechanisms that explain susceptibility to ERB. A physiological test that may assist in predicting ERB is also presented.

  4. 78 FR 5151 - Proposed Amendment of Class E Airspace; Omak, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ... extending upward from 700 feet above the surface and 1,200 feet above the surface at Omak Airport, Omak, WA.... The size and shape of the airspace will remain the same by using the Airport Reference Point in... amended as follows: Paragraph 6005 Class E airspace areas extending upward from 700 feet or more above the...

  5. NASA Constellation Distributed Simulation Middleware Trade Study

    NASA Technical Reports Server (NTRS)

    Hasan, David; Bowman, James D.; Fisher, Nancy; Cutts, Dannie; Cures, Edwin Z.

    2008-01-01

    This paper presents the results of a trade study designed to assess three distributed simulation middleware technologies for support of the NASA Constellation Distributed Space Exploration Simulation (DSES) project and Test and Verification Distributed System Integration Laboratory (DSIL). The technologies are the High Level Architecture (HLA), the Test and Training Enabling Architecture (TENA), and an XML-based variant of Distributed Interactive Simulation (DIS-XML) coupled with the Extensible Messaging and Presence Protocol (XMPP). According to the criteria and weights determined in this study, HLA scores better than the other two for DSES as well as the DSIL.

  6. Methods for MHC genotyping in non-model vertebrates.

    PubMed

    Babik, W

    2010-03-01

    Genes of the major histocompatibility complex (MHC) are considered a paradigm of adaptive evolution at the molecular level and as such are frequently investigated by evolutionary biologists and ecologists. Accurate genotyping is essential for understanding of the role that MHC variation plays in natural populations, but may be extremely challenging. Here, I discuss the DNA-based methods currently used for genotyping MHC in non-model vertebrates, as well as techniques likely to find widespread use in the future. I also highlight the aspects of MHC structure that are relevant for genotyping, and detail the challenges posed by the complex genomic organization and high sequence variation of MHC loci. Special emphasis is placed on designing appropriate PCR primers, accounting for artefacts and the problem of genotyping alleles from multiple, co-amplifying loci, a strategy which is frequently necessary due to the structure of the MHC. The suitability of typing techniques is compared in various research situations, strategies for efficient genotyping are discussed and areas of likely progress in future are identified. This review addresses the well established typing methods such as the Single Strand Conformation Polymorphism (SSCP), Denaturing Gradient Gel Electrophoresis (DGGE), Reference Strand Conformational Analysis (RSCA) and cloning of PCR products. In addition, it includes the intriguing possibility of direct amplicon sequencing followed by the computational inference of alleles and also next generation sequencing (NGS) technologies; the latter technique may, in the future, find widespread use in typing complex multilocus MHC systems. © 2009 Blackwell Publishing Ltd.

  7. Inactivation of Adenovirus Type 5, Rotavirus WA and Male Specific Coliphage (MS2) in Biosolids by Lime Stabilization

    PubMed Central

    Hansen, Jacqueline J.; Warden, Paul S.; Margolin, Aaron B.

    2007-01-01

    The use of lime to reduce or eliminate pathogen content is a cost-effective treatment currently employed in many Class B biosolids production plants in the United States. A bench scale model of lime stabilization was designed to evaluate the survival of adenovirus type 5, rotavirus Wa, and the male specific bacteriophage, MS2, in various matrices. Each virus was initially evaluated independently in a reverse osmosis treated water matrix limed with an aqueous solution of calcium hydroxide for 24-hr at 22 ± 5°C. In all R/O water trials, adenovirus type 5, rotavirus Wa and MS2 were below detectable levels (<100.5 TCID50/mL and <1 PFU/mL respectively) following 0.1-hr of liming. Adenovirus type 5, rotavirus Wa, and MS2, were inoculated into composted, raw and previously limed matrices, representative of sludge and biosolids, to achieve a final concentration of approximately 104 PFU or TCID50/mL. Each matrix was limed for 24-hr at 22 ± 5°C and 4 ± 2°C. In all trials virus was below detectable levels following a 24-hr incubation. The time required for viral inactivation varied depending on the temperature and sample matrix. This research demonstrates reduction of adenovirus type 5, rotavirus Wa, and male-specific bacteriophage, in water, sludge and biosolids matrices following addition of an 8% calcium hydroxide slurry to achieve a pH of 12 for 2-hr reduced to 11.5 for 22-hr by addition of 0.1 N HCl. In these trials, MS2 was a conservative indicator of the efficacy of lime stabilization of adenovirus Type 5 and rotavirus Wa and therefore is proposed as a useful indicator organism. PMID:17431317

  8. 75 FR 33556 - Proposed Amendment of Class E Airspace; Port Angeles, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-14

    ... action proposes to amend Class E airspace at William R. Fairchild International Airport, Port Angeles, WA... proposing this action for the safety and management of Instrument Flight Rules (IFR) operations at the... triplicate to the Docket Management System (see ``ADDRESSES'' section for address and phone number). You may...

  9. 78 FR 55214 - Drawbridge Operation Regulation; Lake Washington Ship Canal, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-10

    ... Operation Regulation; Lake Washington Ship Canal, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of... operating schedule that governs the Burlington Northern Santa Fe (BNSF) Railway Bridge across the Lake... Railway has requested that the draw of the BNSF Railway Bridge across the Lake Washington Ship Canal, mile...

  10. Assessing GPS Constellation Resiliency in an Urban Canyon Environment

    DTIC Science & Technology

    2015-03-26

    Taipei, Taiwan as his area of interest. His GPS constellation is modeled in the Satellite Toolkit ( STK ) where augmentation satellites can be added and...interaction. SEAS also provides a visual display of the simulation which is useful for verification and debugging portions of the analysis. Furthermore...entire system. Interpreting the model is aided by the visual display of the agents moving in the region of inter- est. Furthermore, SEAS collects

  11. Kinematic-PPP using Single/Dual Frequency Observations from (GPS, GLONASS and GPS/GLONASS) Constellations for Hydrography

    NASA Astrophysics Data System (ADS)

    Farah, Ashraf

    2018-03-01

    Global Positioning System (GPS) technology is ideally suited for inshore and offshore positioning because of its high accuracy and the short observation time required for a position fix. Precise point positioning (PPP) is a technique used for position computation with a high accuracy using a single GNSS receiver. It relies on highly accurate satellite position and clock data that can be acquired from different sources such as the International GNSS Service (IGS). PPP precision varies based on positioning technique (static or kinematic), observations type (single or dual frequency) and the duration of observations among other factors. PPP offers comparable accuracy to differential GPS with safe in cost and time. For many years, PPP users depended on GPS (American system) which considered the solely reliable system. GLONASS's contribution in PPP techniques was limited due to fail in maintaining full constellation. Yet, GLONASS limited observations could be integrated into GPS-based PPP to improve availability and precision. As GLONASS reached its full constellation early 2013, there is a wide interest in PPP systems based on GLONASS only and independent of GPS. This paper investigates the performance of kinematic PPP solution for the hydrographic applications in the Nile river (Aswan, Egypt) based on GPS, GLONASS and GPS/GLONASS constellations. The study investigates also the effect of using two different observation types; single-frequency and dual frequency observations from the tested constellations.

  12. 77 FR 41977 - City of Seattle, WA; Notice of Availability of Environmental Assessment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-17

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 553-221--Washington] City of Seattle, WA; Notice of Availability of Environmental Assessment In accordance with the National Environmental Policy Act of 1969 and the Federal Energy Regulatory Commission's (Commission's or FERC's...

  13. Evolutionary analysis of rubella viruses in mainland China during 2010–2012: endemic circulation of genotype 1E and introductions of genotype 2B

    PubMed Central

    Zhu, Zhen; Rivailler, Pierre; Abernathy, Emily; Cui, Aili; Zhang, Yan; Mao, Naiyin; Xu, Songtao; Zhou, Shujie; Lei, Yue; Wang, Yan; Zheng, Huanying; He, Jilan; Chen, Ying; Li, Chongshan; Bo, Fang; Zhao, Chunfang; Chen, Meng; Lu, Peishan; Li, Fangcai; Gu, Suyi; Gao, Hui; Guo, Yu; Chen, Hui; Feng, Daxing; Wang, Shuang; Tang, Xiaomin; Lei, Yake; Feng, Yan; Deng, Lili; Gong, Tian; Fan, Lixia; Xu, Wenbo; Icenogle, Joseph; Chen, Xia; Tian, Hong; Ma, Yan; Liu, Leng; Liu, Li; Liu, Jianfeng; Fu, Hong; Yang, Yuying; Ma, Yujie; Zhao, Hua; Huang, Fang; Hu, Ying; Zhang, Hong; Tian, Xiaoling; Du, Hui; Ma, Xuemin; Zhang, Zhenying; Xu, Jin; Zhou, Jianhui; Ye, Xufang; Li, Jing; Lu, Yiyu; Liu, Wei; Zhang, Yanni; Zhao, Shengcang; Ba, Zhuoma

    2015-01-01

    Rubella remains a significant burden in mainland China. In this report, 667 viruses collected in 24 of 31 provinces of mainland China during 2010–2012 were sequenced and analyzed, significantly extending previous reports on limited numbers of viruses collected before 2010. Only viruses of genotypes 1E and 2B were found. Genotype 1E viruses were found in all 24 provinces. Genotype 1E viruses were likely introduced into mainland China around 1997 and endemic transmission of primarily one lineage became established. Viruses reported here from 2010–2012 are largely in a single cluster within this lineage. Genotype 2B viruses were rarely detected in China prior to 2010. This report documents a previously undetected 2B lineage, which likely became endemic in eastern provinces of China between 2010 and 2012. Bayesian analyses were performed to estimate the evolutionary rates and dates of appearance of the genotype 1E and 2B viral linages in China. A skyline plot of viral population diversity did not provide evidence of reduction of diversity as a result of vaccination, but should be useful as a baseline for such reductions as vaccination programs for rubella become widespread in mainland China. PMID:25613734

  14. Earth Radiation Imbalance from a Constellation of 66 Iridium Satellites: Climate Science Aspects

    NASA Technical Reports Server (NTRS)

    Wiscombe, W.; Chiu, CJ. Y.

    2012-01-01

    The "global warming hiatus" since the 1998 El Nino, highlighted by Meehl et al., and the resulting "missing energy" problem highlighted by Trenberth et al., has opened the door to a more fundamental view of climate change than mere surface air temperature. That new view is based on two variables which are strongly correlated: the rate of change of ocean heat content d(OHC)/dt; and Earth Radiation Imbalance (ERI) at the top of the atmosphere, whose guesstimated range is 0.4 to 0.9 Watts per square meters (this imbalance being mainly due to increasing CO2). The Argo float array is making better and better measurements of OHC. But existing satellite systems cannot measure ERI to even one significant digit. So, climate model predictions of ERI are used in place of real measurements of it, and the satellite data are tuned to the climate model predictions. Some oceanographers say "just depend on Argo for understanding the global warming hiatus and the missing energy", but we don't think this is a good idea because d(OHC)/dt and ERI have different time scales and are never perfectly correlated. We think the ERB community needs to step up to measuring ERI correctly, just as oceanographers have deployed Argo to measure OHC correctly. This talk will overview a proposed constellation of 66 Earth radiation budget instruments, hosted on Iridium satellites, that will actually be able to measure ERI to at least one significant digit, thus enabling a crucial test of climate models. This constellation will also be able to provide ERI at two-hourly time scales and 500-km spatial scales without extrapolations from uncalibrated narrowband geostationary instruments, using the highly successful methods of GRACE to obtain spatial resolution. This high time resolution would make ERI a synoptic variable like temperature, and allow studies of ERI's response to fast-evolving phenomena like dust storms and hurricanes and even brief excursions of Total Solar Irradiance. Time permitting, we

  15. 77 FR 57019 - Drawbridge Operation Regulation; Lake Washington Ship Canal, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ... Ship Canal, mile 0.1, at Seattle, WA. This deviation is necessary to facilitate heavy maintenance on... heavy maintenance on the bridge. The bridge provides 43 feet of vertical clearance above mean high water... experiences heavy waterway usage and is utilized by vessels ranging from commercial tug and barge to pleasure...

  16. 77 FR 55138 - Special Local Regulation: Hydroplane Races in Lake Sammamish, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-07

    ... Local Regulation: Hydroplane Races in Lake Sammamish, WA AGENCY: Coast Guard, DHS. ACTION: Notice of... Races within the Captain of the Port Puget Sound Area of Responsibility for the 2012 Fall Championship... September 30, 2012. This action is necessary to restrict vessel movement in the vicinity of the race courses...

  17. Changing prevalence of hepatitis B virus genotypes in Iceland.

    PubMed

    Björnsdottir, Thora B; Stanzeit, Barbara; Sällberg, Matti; Löve, Arthur; Hultgren, Catharina

    2005-12-01

    At present eight hepatitis B virus (HBV) genotypes have been characterized: A to H. The most common genotype in Northern Europe is genotype A. So far there is no record of the specific HBV genotype distribution in Iceland. Iceland has a small population whose homogeneity has changed due to increasing migration during the past decades. The distribution of HBV genotypes in Iceland was analyzed using sera from 170 Icelandic patients. The samples were obtained before 1989, during an HBV epidemic among intravenous drug users in 1989 to 1992 and after 1994. A fragment of the HBV S-gene was amplified, sequenced and subjected to phylogenetic analysis. Among samples derived before 1989 genotypes A, C, and D were found. Most of the samples diagnosed during the epidemic belonged to genotype D and a smaller portion to genotype A. This suggests that the epidemic was most likely caused either by an endogenous HBV strain or by a strain imported from Europe or the USA. Among samples obtained after 1994, genotypes A to E and G were found, but the majority were of genotypes A, C, and D. This is consistent with an increase in migration and immigration from regions in Asia and Africa during the past 10 years. Thus, the changing prevalence of HBV genotypes in a small isolated community such as Iceland reflects the influence of migration and increasing contacts with regions outside the Western World. Copyright (c) 2005 Wiley-Liss, inc.

  18. β Lup, δ Lup, and τ^1 Lup observed by BRITE-Constellation

    NASA Astrophysics Data System (ADS)

    Cugier, H.; Pigulski, A.

    2017-09-01

    Time-series analysis of BRITE-Constellation photometry of β Lup, δ Lup and τ^1 Lup revealed 16, 22 and four pulsation modes, respectively. An attempt to constrain internal structure of these stars via seismic modelling was also made.

  19. 33 CFR 165.1303 - Puget Sound and adjacent waters, WA-regulated navigation area.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., WA-regulated navigation area. 165.1303 Section 165.1303 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and Limited Access Areas Thirteenth Coast Guard District...

  20. The CEOS-Land Surface Imaging Constellation Portal for GEOSS: A resource for land surface imaging system information and data access

    USGS Publications Warehouse

    Holm, Thomas; Gallo, Kevin P.; Bailey, Bryan

    2010-01-01

    The Committee on Earth Observation Satellites is an international group that coordinates civil space-borne observations of the Earth, and provides the space component of the Global Earth Observing System of Systems (GEOSS). The CEOS Virtual Constellations concept was implemented in an effort to engage and coordinate disparate Earth observing programs of CEOS member agencies and ultimately facilitate their contribution in supplying the space-based observations required to satisfy the requirements of the GEOSS. The CEOS initially established Study Teams for four prototype constellations that included precipitation, land surface imaging, ocean surface topography, and atmospheric composition. The basic mission of the Land Surface Imaging (LSI) Constellation [1] is to promote the efficient, effective, and comprehensive collection, distribution, and application of space-acquired image data of the global land surface, especially to meet societal needs of the global population, such as those addressed by the nine Group on Earth Observations (GEO) Societal Benefit Areas (SBAs) of agriculture, biodiversity, climate, disasters, ecosystems, energy, health, water, and weather. The LSI Constellation Portal is the result of an effort to address important goals within the LSI Constellation mission and provide resources to assist in planning for future space missions that might further contribute to meeting those goals.

  1. [Genotype/phenotype correlation in autism: genetic models and phenotypic characterization].

    PubMed

    Bonnet-Brilhault, F

    2011-02-01

    Autism spectrum disorders are a class of conditions categorized by communication problems, ritualistic behaviors, and deficits in social behaviors. This class of disorders merges a heterogeneous group of neurodevelopmental disorders regarding some phenotypic and probably physiopathological aspects. Genetic basis is well admitted, however, considering phenotypic and genotypic heterogeneity, correspondences between genotype and phenotype have yet to be established. To better identify such correspondences, genetic models have to be identified and phenotypic markers have to be characterized. Recent insights show that a variety of genetic mechanisms may be involved in autism spectrum disorders, i.e. single gene disorders, copy number variations and polygenic mechanisms. These current genetic models are described. Regarding clinical aspects, several approaches can be used in genetic studies. Nosographical approach, especially with the concept of autism spectrum disorders, merges a large group of disorders with clinical heterogeneity and may fail to identify clear genotype/phenotype correlations. Dimensional approach referred in genetic studies to the notion of "Broad Autism Phenotype" related to a constellation of language, personality, and social-behavioral features present in relatives that mirror the symptom domains of autism, but are much milder in expression. Studies of this broad autism phenotype may provide a potentially important complementary approach for detecting the genes involved in these domains. However, control population used in those studies need to be well characterized too. Identification of endophenotypes seems to offer more promising results. Endophenotypes, which are supposed to be more proximal markers of gene action in the same biological pathway, linking genes and complex clinical symptoms, are thought to be less genetically complex than the broader disease phenotype, indexing a limited aspect of genetic risk for the disorder as a whole. However

  2. 78 FR 45056 - Drawbridge Operation Regulation; Lake Washington Ship Canal, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ... Seattle, WA. The deviation is necessary to accommodate vehicular traffic attending football games at Husky... in the closed position two hours before and two hours after each game. Please note that the game times for five of the seven games scheduled for Husky Stadium have not yet been determined due to NCAA...

  3. 77 FR 33307 - Drawbridge Operation Regulation; Lake Washington Ship Canal, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ... Operation Regulation; Lake Washington Ship Canal, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of... operating schedule that governs the Montlake Bridge across the Lake Washington Ship Canal, mile 5.2, at... crosses the Lake Washington Ship Canal at mile 5.2 and while in the closed position provides 30 feet of...

  4. 78 FR 12234 - Anchorages; Captain of the Port Puget Sound Zone, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-22

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 110 [Docket No. USCG-2012-0159] RIN 1625-AA01 Anchorages; Captain of the Port Puget Sound Zone, WA Correction In rule document 2013-03121, appearing on pages 9811-9814 in the issue of Tuesday, February 12, 2013, make the following correction: Sec...

  5. Amidst the Beauty of the Night Sky, which of the Constellations am I?

    NASA Astrophysics Data System (ADS)

    Herrmann, K. A.

    2012-08-01

    A well known constellation am I- I never set in the northern sky. Native Americans and Greeks, you see, Wrote legends when they recognized me. Two close stars still test for keen eyesight. Two point to the North Star - what a light! Look for my galaxies, you know where. I am ____ _____, the _____ ____! © Kimberly A. Herrmann, 2003) I have loved rhyming poetry ever since I can remember - from Dr. Seuss's Green Eggs and Ham and Maurice Sendak's Chicken Soup with Rice, to the works of Shel Silverstein and Jack Prelutsky. It was not until high school, though, that I realized that I could combine two of my loves - those for poetry and astronomy. Since then, I have written almost 100 astronomical riddles and always attempted to include as much astronomy content as possible - even in the riddles about constellations. Consequently, I have found them effective in teaching or reviewing aspects of astronomy in several venues, including college astronomy courses for non-science majors and events with elementary school students. More recently I have used 23 constellation riddles to create informative and entertaining seating slides that have been playing at Lowell Observatory and the Youngstown Planetarium. I hope to have these slides played at other venues as well and also hope to publish my riddles as a series of books someday.

  6. Electrical Arc Ignition Testing for Constellation Program

    NASA Technical Reports Server (NTRS)

    Sparks, Kyle; Gallus, Timothy; Smith, Sarah

    2009-01-01

    NASA Johnson Space Center (JSC) Materials and Processes Branch requested that NASA JSC White Sands Test Facility (WSTF) perform testing for the Constellation Program to evaluate the hazard of electrical arc ignition of materials that could be in close proximity to batteries. Specifically, WSTF was requested to perform wire-break electrical arc tests to determine the current threshold for ignition of generic cotton woven fabric samples with a fixed voltage of 3.7 V, a common voltage for hand-held electrical devices. The wire-break test was developed during a previous test program to evaluate the hazard of electrical arc ignition inside the Extravehicular Mobility Unit [1].

  7. RaInCube: a proposed constellation of precipitation profiling Radars In Cubesat

    NASA Astrophysics Data System (ADS)

    Peral, E.; Tanelli, S.; Haddad, Z. S.; Stephens, G. L.; Im, E.

    2014-12-01

    Precipitation radars in Low-Earth-Orbit provide vertically resolved profiles of rain and snow on a global scale. With the recent advances in miniaturized radar and CubeSat/SmallSat technologies, it would now be feasible to launch multiple copies of the same radar instrument in desirable formations to allow measurements of short time scale evolution of atmospheric processes. One such concept is the novel radar architecture compatible with the 6U CubeSat class that is being developed at JPL by exploiting simplification and miniaturization of the radar subsystems. The RaInCube architecture would significantly reduce the number of components, power consumption and mass with respect to existing spaceborne radars. The baseline RaInCube instrument configuration would be a fixed nadir-pointing profiler at Ka-band with a minimum detectable reflectivity better than +10 dBZ at 250m range resolution and 5 km horizontal resolution. The low cost nature of the RaInCube platform would enable deployment of a constellation of identical copies of the same instrument in various relative positions in LEO to address specific observational gaps left open by the current missions that require high-resolution vertical profiling capability. A constellation of only four RaInCubes would populate the precipitation statistics in a distributed fashion across the globe and across the times of day, and therefore, would enable substantially better sampling of the diurnal cycle statistics. One could extend this scheme by adding more RaInCubes in each of the orbital planes, and phase them once in orbit so that they would be separated by an arbitrary amount of time among them. Wide separations (say 20-30 min) would further extend the sampling of the diurnal cycle to sub-hourly scales. Narrower time separations between RaInCubes would allow studying the evolution of convective systems at the convective time scale in each region of interest and would reveal the dominant modes of evolution of each

  8. An Integrated Watershed and Receiving Water Model for Fecal Coliform Fate and Transport in Sinclair and Dyes Inlets, Puget Sound, WA

    DTIC Science & Technology

    2009-12-01

    xix USLE Universal Soil Loss Equation UV Ultraviolet UZSN Upper Zone Nominal Storage WA-DOE Washington State Department of Ecology WA-DOH...Effective Impervious Area IMPLND Impervious Land Cover INFILT Interflow Inflow Parameter (related to infiltration capacity of the soil ) INSUR...within Watershed (#/Km) SCCWRP Southern California Coastal Water Research Project SCS Soil Conservation Service SGA Shellfish Growing Area SPAWAR

  9. Molecular genotyping of ABO blood groups in some population groups from India.

    PubMed

    Ray, Sabita; Gorakshakar, Ajit C; Vasantha, K; Nadkarni, Anita; Italia, Yazdi; Ghosh, Kanjaksha

    2014-01-01

    Indian population is characterized by the presence of various castes and tribal groups. Various genetic polymorphisms have been used to differentiate among these groups. Amongst these, the ABO blood group system has been extensively studied. There is no information on molecular genotyping of ABO blood groups from India. Therefore, the main objective of this study was to characterize the common A, B and O alleles by molecular analysis in some Indian population groups. One hundred samples from the mixed population from Mumbai, 101 samples from the Dhodia tribe and 100 samples from the Parsi community were included in this study. Initially, the samples were phenotyped by standard serologic techniques. PCR followed by single strand conformational polymorphsim (SSCP) was used for molecular ABO genotyping. Samples showing atypical SSCP patterns were further analysed by DNA sequencing to characterize rare alleles. Seven common ABO alleles with 19 different genotypes were found in the mixed population. The Dhodias showed 12 different ABO genotypes and the Parsis revealed 15 different ABO genotypes with six common ABO alleles identified in each of them. Two rare alleles were also identified. This study reports the distribution of molecular genotypes of ABO alleles among some population groups from India. Considering the extremely heterogeneous nature of the Indian population, in terms of various genotype markers like blood groups, red cell enzymes, etc., many more ABO alleles are likely to be encountered.

  10. 77 FR 44470 - Safety Zone; Seafair Blue Angels Air Show Performance, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ... 1625-AA00 Safety Zone; Seafair Blue Angels Air Show Performance, Seattle, WA AGENCY: Coast Guard, DHS... the safety hazards associated with the Seafair Blue Angels Air Show Performance which include low... Coast Guard is establishing this rule because the current regulation associated with the Seafair Blue...

  11. Asynchronous Processing of a Constellation of Geostationary and Polar-Orbiting Satellites for Fire Detection and Smoke Estimation

    NASA Astrophysics Data System (ADS)

    Hyer, E. J.; Peterson, D. A.; Curtis, C. A.; Schmidt, C. C.; Hoffman, J.; Prins, E. M.

    2014-12-01

    The Fire Locating and Monitoring of Burning Emissions (FLAMBE) system converts satellite observations of thermally anomalous pixels into spatially and temporally continuous estimates of smoke release from open biomass burning. This system currently processes data from a constellation of 5 geostationary and 2 polar-orbiting sensors. Additional sensors, including NPP VIIRS and the imager on the Korea COMS-1 geostationary satellite, will soon be added. This constellation experiences schedule changes and outages of various durations, making the set of available scenes for fire detection highly variable on an hourly and daily basis. Adding to the complexity, the latency of the satellite data is variable between and within sensors. FLAMBE shares with many fire detection systems the goal of detecting as many fires as possible as early as possible, but the FLAMBE system must also produce a consistent estimate of smoke production with minimal artifacts from the changing constellation. To achieve this, NRL has developed a system of asynchronous processing and cross-calibration that permits satellite data to be used as it arrives, while preserving the consistency of the smoke emission estimates. This talk describes the asynchronous data ingest methodology, including latency statistics for the constellation. We also provide an overview and show results from the system we have developed to normalize multi-sensor fire detection for consistency.

  12. Mission Status for Earth Science Constellation MOWG Meeting at KSC: EOS Aura

    NASA Technical Reports Server (NTRS)

    Fisher, Dominic

    2017-01-01

    This will be presented at the Earth Science Constellation Mission Operations Working Group (MOWG) meeting at KSC (Kennedy Space Center) in December 2017 to discus EOS (Earth Observing System) Aura status. Reviewed and approved by Eric Moyer, ESMO (Earth Sciences Mission Operations) Deputy Project Manager.

  13. The HUMSAT System: a CubeSat-based Constellation for In-situ and Inexpensive Environmental Measurements

    NASA Astrophysics Data System (ADS)

    Tubío-Pardavila, R.; Vigil, S. A.; Puig-Suari, J.; Aguado Agelet, F.

    2014-12-01

    There is a requirement for low cost in-situ measurements of environmental parameters such as air quality, meteorological data, and water quality in remote areas. Currently available solutions for such measurements include remote sensing from satellite and aircraft platforms, and in-situ measurements from mobile and aircraft platforms. Fixed systems such as eddy covariance networks, tall towers, and the Total Carbon Column Observing Network (TCCON) are providing precision greenhouse gas measurements. Within this context, the HUMSAT system designed by the University of Vigo (Spain) will complement existing high-precision measurement systems with low cost in-situ ground based sensors in remote locations using a constellation of CubeSats as a communications relay. The HUMSAT system standardizes radio communications in between deployed sensors and the CubeSats of the constellation, which act as store and forward satellites to ground stations for uploading to the internet. Current ground stations have been established at the University of Vigo (Spain) and California Polytechnic State University (Cal Poly). Users of the system may deploy their own environmental sensors to meet local requirements. The sensors will be linked to a low-cost satellite data transceiver using a standard HUMSAT protocol. The transceiver is capable of receiving data from the HUMSAT constellation to remotely reconfigure sensors without the need of physically going to the sensor location. This transceiver uses a UHF channel around 437 MHz to exchange short data messages with the sensors. These data messages can contain up to 32 bytes of useful information and are transmitted at a speed around 300 bps. The protocol designed for this system handles the access to the channel by all these elements and guarantees a correct transmission of the information in such an scenario. The University of Vigo has launched the first satellite of the constellation, the HUMSAT-D CubeSat in November 2013 and has

  14. Constellation X-Ray Mission and Support

    NASA Technical Reports Server (NTRS)

    Tananbaum, H.; Grady, Jean (Technical Monitor)

    2005-01-01

    This Final Report summarizes work performed by the Smithsonian Astrophysical Observatory (SAO) for NASA Goddard Space Flight Center (GSFC) under Cooperative Agreement NCC5-368. The Agreement is entitled "Constellation X-ray Mission Study and Support." The report covers the full duration of the Agreement which ran from October 1,1998 to October 14,2004. Included in the report is a description of previously unreported work that was performed between October 2003 and the end of the Agreement. For convenience, the previously unreported work is covered first in Section 2.0. Then, an overall summary of all work performed under the Agreement is presented in Section 3. Section 4.0 contains a list of all formal reports that SAO has submitted to GSFC along with publications and presentations at various conferences.

  15. 75 FR 43563 - Pendleton Woolen Mills, Inc., Washougal, WA; Notice of Negative Determination Regarding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-26

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-72,194] Pendleton Woolen Mills, Inc., Washougal, WA; Notice of Negative Determination Regarding Application for Reconsideration By application dated May 4, 2010, a petitioner requested administrative reconsideration of the Department's...

  16. Representativeness of Tuberculosis Genotyping Surveillance in the United States, 2009–2010

    PubMed Central

    Shak, Emma B.; Cowan, Lauren; Starks, Angela M.; Grant, Juliana

    2015-01-01

    Genotyping of Mycobacterium tuberculosis isolates contributes to tuberculosis (TB) control through detection of possible outbreaks. However, 20% of U.S. cases do not have an isolate for testing, and 10% of cases with isolates do not have a genotype reported. TB outbreaks in populations with incomplete genotyping data might be missed by genotyping-based outbreak detection. Therefore, we assessed the representativeness of TB genotyping data by comparing characteristics of cases reported during January 1, 2009–December 31, 2010, that had a genotype result with those cases that did not. Of 22,476 cases, 14,922 (66%) had a genotype result. Cases without genotype results were more likely to be patients <19 years of age, with unknown HIV status, of female sex, U.S.-born, and with no recent history of homelessness or substance abuse. Although cases with a genotype result are largely representative of all reported U.S. TB cases, outbreak detection methods that rely solely on genotyping data may underestimate TB transmission among certain groups. PMID:26556930

  17. BRITE-Constellation Science Operations

    NASA Astrophysics Data System (ADS)

    Kuschnig, R.

    2017-09-01

    BRITE-Constellation is a nanosatellite mission designed for stellar astrophysical research in collaboration between Austria, Canada and Poland. A fleet of six spacecrafts was funded, built and launched, two from each country, all designed to perform precise time-series photometry of the brightest stars in the sky. While the spacecrafts have the same basic design, three satellites host an instrument sensitive in a red bandpass, the others, for a blue wavelength range. From the six satellites launched, five are operational. The sixth one did not separate from the upper stage of the rocket and remains idle. The first pair, the Austrian satellites, started to collect science measurements with their wide field (˜24°) cameras in early December 2013. Since then, more than 340 stars were observed during 16 campaigns, the majority for more than 100 days (up to 168 days) continuously. In total, more than 2.1 million measurements have been collected so far. Originally, the limiting magnitude for target stars was set to \\mag(V)=4. However, even stars as faint as \\mag(V)=6.5 have been observed with sufficient precision. This is a review of science operations conducted during the past 3.5 years.

  18. A mars communication constellation for human exploration and network science

    NASA Astrophysics Data System (ADS)

    Castellini, Francesco; Simonetto, Andrea; Martini, Roberto; Lavagna, Michèle

    2010-01-01

    This paper analyses the possibility of exploiting a small spacecrafts constellation around Mars to ensure a complete and continuous coverage of the planet, for the purpose of supporting future human and robotic operations and taking advantage of optical transmission techniques. The study foresees such a communications mission to be implemented at least after 2020 and a high data-rate requirement is imposed for the return of huge scientific data from massive robotic exploration or to allow video transmissions from a possible human outpost. In addition, the set-up of a communication constellation around Mars would give the opportunity of exploiting this multi-platform infrastructure to perform network science, that would largely increase our knowledge of the planet. The paper covers all technical aspects of a feasibility study performed for the primary communications mission. Results are presented for the system trade-offs, including communication architecture, constellation configuration and transfer strategy, and the mission analysis optimization, performed through the application of a multi-objective genetic algorithm to two models of increasing difficulty for the low-thrust trajectory definition. The resulting communication architecture is quite complex and includes six 530 kg spacecrafts on two different orbital planes, plus one redundant unit per plane, that ensure complete coverage of the planet’s surface; communications between the satellites and Earth are achieved through optical links, that allow lower mass and power consumption with respect to traditional radio-frequency technology, while inter-satellite links and spacecrafts-to-Mars connections are ensured by radio transmissions. The resulting data-rates for Earth-Mars uplink and downlink, satellite-to-satellite and satellite-to-surface are respectively 13.7 Mbps, 10.2 Mbps, 4.8 Mbps and 4.3 Mbps, in worst-case. Two electric propulsion modules are foreseen, to be placed on a C3˜0 escape orbit with two

  19. 75 FR 58429 - Notice of Inventory Completion: Northwest Museum of Arts & Culture, Spokane, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... possession of the Northwest Museum of Arts & Culture, aka Eastern Washington State Historical Society... of Arts & Culture, Spokane, WA AGENCY: National Park Service, Interior. ACTION: Notice. Notice is... Arts & Culture professional staff in consultation with representatives of the Confederated Tribes of...

  20. 77 FR 37600 - Safety Zone; Arctic Drilling and Support Vessels, Puget Sound, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... made local inquiries and chartered a vessel to observe the mobile offshore drilling unit (MODU) KULLUK... 1625-AA00 Safety Zone; Arctic Drilling and Support Vessels, Puget Sound, WA AGENCY: Coast Guard, DHS... nineteen vessels associated with Arctic drilling as well as their lead towing vessels while those vessels...

  1. 33 CFR 110.230 - Anchorages, Captain of the Port Puget Sound Zone, WA.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Anchorages, Captain of the Port... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.230 Anchorages, Captain of the Port Puget Sound Zone, WA. (a) Anchorage grounds. All coordinates are expressed in North American Datum...

  2. 33 CFR 110.230 - Anchorages, Captain of the Port Puget Sound Zone, WA.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Anchorages, Captain of the Port... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.230 Anchorages, Captain of the Port Puget Sound Zone, WA. (a) Anchorage grounds. All coordinates are expressed in North American Datum...

  3. Constellation's First Flight Test: Ares I-X

    NASA Technical Reports Server (NTRS)

    Davis, Stephan R.; Askins, Bruce R.

    2010-01-01

    On October 28, 2009, NASA launched Ares I-X, the first flight test of the Constellation Program that will send human beings to the Moon and beyond. This successful test is the culmination of a three-and-a-half-year, multi-center effort to design, build, and fly the first demonstration vehicle of the Ares I crew launch vehicle, the successor vehicle to the Space Shuttle. The suborbital mission was designed to evaluate the atmospheric flight characteristics of a vehicle dynamically similar to Ares I; perform a first stage separation and evaluate its effects; characterize and control roll torque; stack, fly, and recover a solid-motor first stage testing the Ares I parachutes; characterize ground, flight, and reentry environments; and develop and execute new ground hardware and procedures. Built from existing flight and new simulator hardware, Ares I-X integrated a Shuttle-heritage four-segment solid rocket booster for first stage propulsion, a spacer segment to simulate a five-segment booster, Peacekeeper axial engines for roll control, and Atlas V avionics, as well as simulators for the upper stage, crew module, and launch abort system. The mission leveraged existing logistical and ground support equipment while also developing new ones to accommodate the first in-line rocket for flying astronauts since the Saturn IB last flew from Kennedy Space Center (KSC) in 1975. This paper will describe the development and integration of the various vehicle and ground elements, from conception to stacking in KSC s Vehicle Assembly Building; hardware performance prior to, during, and after the launch; and preliminary lessons and data gathered from the flight. While the Constellation Program is currently under review, Ares I-X has and will continue to provide vital lessons for NASA personnel in taking a vehicle concept from design to flight.

  4. The CEOS Atmospheric Composition Constellation: Enhancing the Value of Space-Based Observations

    NASA Technical Reports Server (NTRS)

    Eckman, Richard; Zehner, Claus; Al-Saadi, Jay

    2015-01-01

    The Committee on Earth Observation Satellites (CEOS) coordinates civil space-borne observations of the Earth. Participating agencies strive to enhance international coordination and data exchange and to optimize societal benefit. In recent years, CEOS has collaborated closely with the Group on Earth Observations (GEO) in implementing the Global Earth Observing System of Systems (GEOSS) space-based objectives. The goal of the CEOS Atmospheric Composition Constellation (ACC) is to collect and deliver data to improve monitoring, assessment and predictive capabilities for changes in the ozone layer, air quality and climate forcing associated with changes in the environment through coordination of existing and future international space assets. A project to coordinate and enhance the science value of a future constellation of geostationary sensors measuring parameters relevant to air quality supports the forthcoming European Sentinel-4, Korean GEMS, and US TEMPO missions. Recommendations have been developed for harmonization to mutually improve data quality and facilitate widespread use of the data products.

  5. Malaria treatment-seeking behaviour and related factors of Wa ethnic minority in Myanmar: a cross-sectional study

    PubMed Central

    2012-01-01

    Background In Southeast Asia, data on malaria treatment-seeking behaviours and related affecting factors are rare. The population of the Wa ethnic in Myanmar has difficulty in accessing formal health care. To understand malaria treatment-seeking behaviour and household-affecting factors of the Wa people, a cross-sectional study carried out in Shan Special Region II, Myanmar. Methods The two methods, questionnaire-based household surveys to household heads and in-depth interviews to key informants, were carried out independently. The proportion of treatment-seeking patterns was calculated. Logistic regression was used to determine affecting factors of treatment-seeking. Qualitative data were analysed by using Text Analysis Markup System. Results Overall, 87.5% of the febrile population sought treatment, but only 32.0% did so within 24 hours. The proportion accessing the retail sector (79.6%) was statistically significant higher (P<0.0001) than accessing the public sector (10.6%). Multivariable logistic regression analysis identified family income, distances from a health facility, family decision and patient characteristics being independently associated with delayed malaria treatment. Conclusion Malaria treatment-seeking behaviour is not appropriate, and affecting factors include health service systems, social and cultural factors in Wa State of Myanmar. PMID:23237576

  6. Requirements and Sizing Investigation for the Constellation Space Suit Portable Life Support System Trace Contaminant Control

    NASA Technical Reports Server (NTRS)

    Jennings, Mallory A.; Paul, Heather L.; Waguespack, Glenn M.

    2010-01-01

    This presentation summarized the results of a trade study that evaluated whether trace contaminant control within the Constellation Spacesuit PLSS could be achieved without a Trace Contaminant Control System (TCCS) by relying on suit leakage, ullage loss from the carbon dioxide and humidity control system, and other factors. Mallory Jennings and Dr. Glenn Waguespack studied trace contaminant generation rates to verify that values reflected the latest designs for Constellation spacesuit system pressure garment materials and PLSS hardware. They also calculated TCCS sizing and conducted a literature survey to review the latest developments in trace contaminant technologies.

  7. Space Technology 5: Pathfinder for Future Micro-Sat Constellations

    NASA Technical Reports Server (NTRS)

    Carlisle, Candace; Finnegan, Eric

    2004-01-01

    The Space Technology 5 (ST-5) Project, currently in the implementation phase, is part of the National Aeronautics and Space Administration (NASA) s New Millennium Program (NMP). ST-5 will consist of a constellation of three miniature satellites, each with mass less than 25 kg and size approximately 60 cm by 30 cm. ST-5 addresses technology challenges, as well as fabrication, assembly, test and operations strategies for future micro-satellite missions. ST-5 will be deployed into a highly eccentric, geo-transfer orbit (GTO). This will expose the spacecraft to a high radiation environment as well as provide a low level magnetic background. A three-month flight demonstration phase is planned to validate the technologies and demonstrate concepts for future missions. Each ST-5 spacecraft incorporates NMP competitively-selected breakthrough technologies. These include Cold Gas Micro-Thrusters for propulsion and attitude control, miniature X-band transponder for space-ground communications, Variable Emittance Coatings for dynamic thermal control, and CULPRiT ultra low power logic chip used for Reed-Solomon encoding. The ST-5 spacecraft itself is a technology that can be infused into future missions. It is a fully functional micro-spacecraft built within tight volume and mass constraints. It is built to withstand a high radiation environment, large thermal variations, and high launch loads. The spacecraft power system is low-power and low-voltage, and is designed to turn on after separation &om the launch vehicle. Some of the innovations that are included in the ST-5 design are a custom spacecraft deployment structure, magnetometer deployment boom, nutation damper, X-band antenna, miniature spinning sun sensor, solar array with triple junction solar cells, integral card cage assembly containing single card Command and Data Handling and Power System Electronics, miniature magnetometer, and lithium ion battery. ST-5 will demonstrate the ability of a micro satellite to perform

  8. Molecular genotyping of ABO blood groups in some population groups from India

    PubMed Central

    Ray, Sabita; Gorakshakar, Ajit C.; Vasantha, K.; Nadkarni, Anita; Italia, Yazdi; Ghosh, Kanjaksha

    2014-01-01

    Background & objectives: Indian population is characterized by the presence of various castes and tribal groups. Various genetic polymorphisms have been used to differentiate among these groups. Amongst these, the ABO blood group system has been extensively studied. There is no information on molecular genotyping of ABO blood groups from India. Therefore, the main objective of this study was to characterize the common A, B and O alleles by molecular analysis in some Indian population groups. Methods: One hundred samples from the mixed population from Mumbai, 101 samples from the Dhodia tribe and 100 samples from the Parsi community were included in this study. Initially, the samples were phenotyped by standard serologic techniques. PCR followed by single strand conformational polymorphsim (SSCP) was used for molecular ABO genotyping. Samples showing atypical SSCP patterns were further analysed by DNA sequencing to characterize rare alleles. Results: Seven common ABO alleles with 19 different genotypes were found in the mixed population. The Dhodias showed 12 different ABO genotypes and the Parsis revealed 15 different ABO genotypes with six common ABO alleles identified in each of them. Two rare alleles were also identified. Interpretation & conclusions: This study reports the distribution of molecular genotypes of ABO alleles among some population groups from India. Considering the extremely heterogeneous nature of the Indian population, in terms of various genotype markers like blood groups, red cell enzymes, etc., many more ABO alleles are likely to be encountered. PMID:24604045

  9. 77 FR 35850 - Safety Zone; F/V Deep Sea, Penn Cove, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-15

    ... 1625-AA00 Safety Zone; F/V Deep Sea, Penn Cove, WA AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a safety zone around the Fishing Vessel (F/V) Deep Sea... with the sunken F/V Deep Sea. B. Basis and Purpose On the evening of May 13, 2012, the F/V Deep Sea...

  10. EOS Aqua: Mission Status at the Earth Science Constellation (ESC) Mission Operations Working Group (MOWG) Meeting at the Kennedy Space Center (KSC)

    NASA Technical Reports Server (NTRS)

    Guit, Bill

    2017-01-01

    This presentation at the Earth Science Constellation Mission Operations Working Group meeting at KSC in December 2017 to discuss EOS (Earth Observing System) Aqua Earth Science Constellation status. Reviewed and approved by Eric Moyer, ESMO (Earth Science Mission Operations) Deputy Project Manager.

  11. Phylogeny of Theileria buffeli genotypes identified in the South African buffalo (Syncerus caffer) population.

    PubMed

    Chaisi, Mamohale E; Collins, Nicola E; Oosthuizen, Marinda C

    2014-08-29

    Theileria buffeli/orientalis is a group of benign and mildly pathogenic species of cattle and buffalo in various parts of the world. In a previous study, we identified T. buffeli in blood samples originating from the African buffalo (Syncerus caffer) in the Hluhluwe-iMfolozi Game Park (HIP) and the Addo Elephant Game Park (AEGP) in South Africa. The aim of this study was to characterise the 18S rRNA gene and complete internal transcribed spacer (ITS1-5.8S-ITS2) region of T. buffeli samples, and to establish the phylogenetic position of this species based on these loci. The 18S rRNA gene and the complete ITS region were amplified from DNA extracted from blood samples originating from buffalo in HIP and AEGP. The PCR products were cloned and the resulting recombinants sequenced. We identified novel T. buffeli-like 18S rRNA and ITS genotypes from buffalo in the AEGP, and novel Theileria sinensis-like 18S rRNA genotypes from buffalo in the HIP. Phylogenetic analyses indicated that the T. buffeli-like sequences were similar to T. buffeli sequences from cattle and buffalo in China and India, and the T. sinensis-like sequences were similar to T. sinensis 18S rRNA sequences of cattle and yak in China. There was extensive sequence variation between the novel T. buffeli genotypes of the African buffalo and previously described T. buffeli and T. sinensis genotypes. The presence of organisms with T. buffeli-like and T. sinensis-like genotypes in the African buffalo could be of significant importance, particularly to the cattle industry in South Africa as these animals might act as sources of infections to naïve cattle. This is the first report on the characterisation of the full-length 18S rRNA gene and ITS region of T. buffeli and T. sinensis genotypes in South Africa. Our study provides invaluable information towards the classification of this complex group of benign and mildly pathogenic species. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Linking Satellites Via Earth "Hot Spots" and the Internet to Form Ad Hoc Constellations

    NASA Technical Reports Server (NTRS)

    Mandl, Dan; Frye, Stu; Grosvenor, Sandra; Ingram, Mary Ann; Langley, John; Miranda, Felix; Lee, Richard Q.; Romanofsky, Robert; Zaman, Afoz; Popovic, Zoya

    2004-01-01

    As more assets are placed in orbit, opportunities emerge to combine various sets of satellites in temporary constellations to perform collaborative image collections. Often, new operations concepts for a satellite or set of satellites emerge after launch. To the degree with which new space assets can be inexpensively and rapidly integrated into temporary or "ad hoc" constellations, will determine whether these new ideas will be implemented or not. On the Earth Observing 1 (EO-1) satellite, a New Millennium Program mission, a number of experiments were conducted and are being conducted to demonstrate various aspects of an architecture that, when taken as a whole, will enable progressive mission autonomy. In particular, the target architecture will use adaptive ground antenna arrays to form, as close as possible, the equivalent of wireless access points for low earth orbiting satellites. Coupled with various ground and flight software and the Internet. the architecture enables progressive mission autonomy. Thus, new collaborative sensing techniques can be implemented post-launch. This paper will outline the overall operations concept and highlight details of both the research effort being conducted in constellations, mission autonomy and

  13. 78 FR 39594 - Safety Zone; Seafair Blue Angels Air Show Performance, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-02

    ... Zone; Seafair Blue Angels Air Show Performance, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of regulation. SUMMARY: The Coast Guard will enforce the annual Seafair Blue Angels Air Show.... This safety zone is being enforced for the Patriots Jet Team, which will be flying in place of the Blue...

  14. Requirements and Sizing Investigation for Constellation Space Suit Portable Life Support System Trace Contaminant Control

    NASA Technical Reports Server (NTRS)

    Paul, Heather L.; Jennings, Mallory A.; Waguespack, Glenn

    2010-01-01

    The Trace Contaminant Control System (TCCS), located within the ventilation loop of the Constellation Space Suit Portable Life Support System (PLSS), is responsible for removing hazardous trace contaminants from the space suit ventilation flow. This paper summarizes the results of a trade study that evaluated if trace contaminant control could be accomplished without a TCCS, relying on suit leakage, ullage loss from the carbon dioxide and humidity control system, and other factors. Trace contaminant generation rates were revisited to verify that values reflect the latest designs for Constellation Space Suit System (CSSS) pressure garment materials and PLSS hardware. Additionally, TCCS sizing calculations were performed and a literature survey was conducted to review the latest developments in trace contaminant technologies.

  15. Science and the Constellation Systems Program Office

    NASA Technical Reports Server (NTRS)

    Mendell, Wendell

    2007-01-01

    An underlying tension has existed throughout the history of NASA between the human spaceflight programs and the external scientific constituencies of the robotic exploration programs. The large human space projects have been perceived as squandering resources that might otherwise be utilized for scientific discoveries. In particular, the history of the relationship of science to the International Space Station Program has not been a happy one. The leadership of the Constellation Program Office, created in NASA in October, 2005, asked me to serve on the Program Manager s staff as a liaison to the science community. Through the creation of my position, the Program Manager wanted to communicate and elucidate decisions inside the program to the scientific community and, conversely, ensure that the community had a voice at the highest levels within the program. Almost all of my technical contributions at NASA, dating back to the Apollo Program, has been within the auspices of what is now known as the Science Mission Directorate. However, working at the Johnson Space Center, where human spaceflight is the principal activity, has given me a good deal of incidental contact and some more direct exposure through management positions to the structures and culture of human spaceflight programs. I entered the Constellation family somewhat naive but not uninformed. In addition to my background in NASA science, I have also written extensively over the past 25 years on the topic of human exploration of the Moon and Mars. (See, for example, Mendell, 1985). I have found that my scientific colleagues generally have little understanding of the structure and processes of a NASA program office; and many of them do not recognize the name, Constellation. In many respects, the international ILEWG community is better informed. Nevertheless, some NASA decision processes on the role of science, particularly with respect to the formulation of a lunar surface architecture, are not well known

  16. Temporal Dynamics and Decay of Putatively Allochthonous and Autochthonous Viral Genotypes in Contrasting Freshwater Lakes

    PubMed Central

    Barbosa, Jorge G.; Brown, Julia M.; Donelan, Ryan P.; Eaglesham, James B.; Eggleston, Erin M.; LaBarre, Brenna A.

    2012-01-01

    Aquatic viruses play important roles in the biogeochemistry and ecology of lacustrine ecosystems; however, their composition, dynamics, and interactions with viruses of terrestrial origin are less extensively studied. We used a viral shotgun metagenomic approach to elucidate candidate autochthonous (i.e., produced within the lake) and allochthonous (i.e., washed in from other habitats) viral genotypes for a comparative study of their dynamics in lake waters. Based on shotgun metagenomes prepared from catchment soil and freshwater samples from two contrasting lakes (Cayuga Lake and Fayetteville Green Lake), we selected two putatively autochthonous viral genotypes (phycodnaviruses likely infecting algae and cyanomyoviruses likely infecting picocyanobacteria) and two putatively allochthonous viral genotypes (geminiviruses likely infecting terrestrial plants and circoviruses infecting unknown hosts but common in soil libraries) for analysis by genotype-specific quantitative PCR (TaqMan) applied to DNAs from viruses in the viral size fraction of lake plankton, i.e., 0.2 μm > virus > 0.02 μm. The abundance of autochthonous genotypes largely reflected expected host abundance, while the abundance of allochthonous genotypes corresponded with rainfall and storm events in the respective catchments, suggesting that viruses with these genotypes may have been transported to the lake in runoff. The decay rates of allochthonous and autochthonous genotypes, assessed in incubations where all potential hosts were killed, were generally lower (0.13 to 1.50% h−1) than those reported for marine virioplankton but similar to those for freshwater virioplankton. Both allochthonous and autochthonous viral genotypes were detected at higher concentrations in subsurface sediments than at the water-sediment interface. Our data indicate that putatively allochthonous viruses are present in lake plankton and sediments, where their temporal dynamics reflect active transport to the lake during

  17. Audiomagnetotelluric exploration across the Waíanae Range, Óahu, Hawaíi

    NASA Astrophysics Data System (ADS)

    Sigurdardottir, T. D.; Thomas, D. M.; Wallin, E.; Winchester, C.; Sinton, J. M.

    2015-12-01

    The audiomagnetotelluric (AMT) method is capable of providing direct evidence of a geothermal resource within the extinct Waíanae volcano, Óahu, Hawaíi. Geothermal systems are becoming an increasingly important energy source worldwide. With electric energy costs in Hawaíi the most expensive in the US (30.54 cents/kWh), it is important to investigate the potential of local geothermal resources. Slightly elevated temperature and chloride concentrations, measured in the 1970's at wells in the upper Lualualei Valley indicate the possibility of a geothermal resource. Previous geophysical investigations: self-potential, rotating quadripole resistivity, and shallow soil temperature surveys in the caldera measured low resistivity values. Resistivity is related to rock characteristics (e.g., porosity, saturation, salinity, temperature, chemistry, and the presence of weathered minerals). We are investigating the area further using the AMT method. We have collected profiles of AMT measurements across the Lualualei Valley and the Waíanae caldera boundary. Anthropogenic noise and access in this area is problematic. Electrical noise, originating from power lines along roads and very low frequency radio towers in the vicinity, add noise to the data. Limited access to sites on military lands inhibit data collection. However, preliminary results show that we have successfully imaged the expected higher resistivity values as our profiles cross the mountains bounding the caldera. As data continue to be collected across the Waíanae Caldera and Range and we begin modeling our data in two dimensions, we expect to be able to identify water table elevations, detect lateral variability between salt and fresh water saturation, estimate thickness of the freshwater lens and depth to the transition zone, image fault structures at the caldera boundary, and with enough sensitivity to conductivity, we can identify regions of elevated temperature.

  18. 75 FR 81641 - Odessa Subarea Special Study; Adams, Franklin, Grant, and Lincoln Counties, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... DEPARTMENT OF THE INTERIOR Bureau of Reclamation [INT-DES 10-54] Odessa Subarea Special Study...). SUMMARY: The Bureau of Reclamation is extending the comment period for the Odessa Subarea Special Study... 83706-1234; telephone: (208) 378-5012. Libraries Ritzville Public Library, 302 West Main, Ritzville, WA...

  19. 77 FR 40521 - Security Zones, Seattle's Seafair Fleet Week Moving Vessels, Puget Sound, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-10

    ... 1625-AA87 Security Zones, Seattle's Seafair Fleet Week Moving Vessels, Puget Sound, WA AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: The U.S. Coast Guard is establishing security zones around designated participating vessels that are not protected by the Naval Vessel Protection Zone in Seattle's...

  20. 77 FR 38236 - Special Local Regulation, Underwater Music Festival, Carr Inlet, Cutts Island, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ...-AA08 Special Local Regulation, Underwater Music Festival, Carr Inlet, Cutts Island, WA AGENCY: Coast... ensure the safety of the maritime public during the Underwater Music Festival and would do so by... Music Festival is an event which includes musical performances from a barge. Spectators approach the...

  1. 78 FR 20852 - Safety Zones; Marine Week Air Ground Demonstration, Lake Washington; Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-08

    ...-AA00 Safety Zones; Marine Week Air Ground Demonstration, Lake Washington; Seattle, WA AGENCY: Coast... safety zones around vessels and persons involved in the Marine Week Seattle Special Marine Air Ground...: Docket Management Facility (M-30), U.S. Department of Transportation, West Building Ground Floor, Room...

  2. 77 FR 25590 - Drawbridge Operation Regulation; Lake Washington Ship Canal, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ...The Coast Guard has issued a temporary deviation from the operating schedule that governs University Bridge across the Lake Washington Ship Canal, mile 4.3, at Seattle, WA. This deviation is necessary to accommodate the Beat the Bridge charity foot race scheduled for Sunday, May 20, 2012. This deviation allows the bridge to remain in the closed position to allow safe movement of event participants.

  3. 77 FR 25079 - Drawbridge Operation Regulation; Lake Washington Ship Canal, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ...The Coast Guard has issued a temporary deviation from the operating schedule that governs the Montlake Bridge across the Lake Washington Ship Canal, mile 5.2, at Seattle, WA. This deviation is necessary to accommodate the Beat the Bridge charity foot race scheduled for Sunday, May 20, 2012. This deviation allows the bridge to remain in the closed position to allow safe movement of event participants.

  4. Intra-genotypic Diversity of Archival G4P[8] Human Rotaviruses from Washington, DC

    PubMed Central

    McDonald, Sarah M.; Davis, Kristin; McAllen, John K.; Spiro, David J.; Patton, John T.

    2011-01-01

    Group A human rotaviruses (RVs) remain the most frequently detected viral agents associated with acute gastroenteritis in infants and young children. Despite their medical importance, relatively few complete genome sequences have been determined for commonly circulating G/P-type strains (i.e., G1P[8], G2P[4], G3P[8], G4P[8], and G9P[8]). In the current study, we sequenced the genomes of 11 G4P[8] isolates from stool specimens that were collected in Washington, DC during the years of 1974-1991. We found that the VP7-VP4-VP6-VP1-VP2-VP3-NSP1-NSP2-NSP3-NSP4-NSP5/6-encoding genes of all 11 G4P[8] RVs have the genotypes of G4-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1. By constructing phylogenetic trees for each gene, extensive intra-genotypic diversity was revealed among the G4P[8] RVs, and new sub-genotype gene alleles were identified. Several of these alleles are nearly identical to those of G3P[8] isolates previously sequenced from this same Washington, DC collection, strongly suggesting that the RVs underwent gene reassortment. On the other hand, we observed that some G4P[8] RVs exhibit completely different allele-based genome constellations, despite being collected during the same epidemic season; there was no evidence of gene reassortment between these strains. This observation extends our previous findings and supports the notion that stable, genetically-distinct clades of human RVs with the same G/P-type can co-circulate in a community. Interestingly, the sub-genotype gene alleles found in some of the DC RVs share a close evolutionary relationship with genes of more contemporary human strains. Thus, archival human RVs sequenced in this study might represent evolutionary precursors to modern-day strains. PMID:21712102

  5. Study of mobile satellite network based on GEO/LEO satellite constellation

    NASA Astrophysics Data System (ADS)

    Hu, Xiulin; Zeng, Yujiang; Wang, Ying; Wang, Xianhui

    2005-11-01

    Mobile satellite network with Inter Satellite Links (ISLs), which consists of non-geostationary satellites, has the characteristic of network topology's variability. This is a great challenge to the design and management of mobile satellite network. This paper analyzes the characteristics of mobile satellite network, takes multimedia Quality of Service (QoS) as the chief object and presents a reference model based on Geostationary Earth Orbit (GEO)/ Low Earth Orbit (LEO) satellite constellation which adapts to the design and management of mobile satellite network. In the reference model, LEO satellites constitute service subnet with responsibility for the access, transmission and switch of the multimedia services for mobile users, while GEO satellites constitute management subnet taking on the centralized management to service subnet. Additionally ground control centre realizes the whole monitoring and control via management subnet. Comparing with terrestrial network, the above reference model physically separates management subnet from service subnet, which not only enhances the advantage of centralized management but also overcomes the shortcoming of low reliability in terrestrial network. Routing of mobile satellite network based on GEO/LEO satellite constellation is also discussed in this paper.

  6. Estimating Tropical Cyclone Surface Wind Field Parameters with the CYGNSS Constellation

    NASA Astrophysics Data System (ADS)

    Morris, M.; Ruf, C. S.

    2016-12-01

    A variety of parameters can be used to describe the wind field of a tropical cyclone (TC). Of particular interest to the TC forecasting and research community are the maximum sustained wind speed (VMAX), radius of maximum wind (RMW), 34-, 50-, and 64-kt wind radii, and integrated kinetic energy (IKE). The RMW is the distance separating the storm center and the VMAX position. IKE integrates the square of surface wind speed over the entire storm. These wind field parameters can be estimated from observations made by the Cyclone Global Navigation Satellite System (CYGNSS) constellation. The CYGNSS constellation consists of eight small satellites in a 35-degree inclination circular orbit. These satellites will be operating in standard science mode by the 2017 Atlantic TC season. CYGNSS will provide estimates of ocean surface wind speed under all precipitating conditions with high temporal and spatial sampling in the tropics. TC wind field data products can be derived from the level-2 CYGNSS wind speed product. CYGNSS-based TC wind field science data products are developed and tested in this paper. Performance of these products is validated using a mission simulator prelaunch.

  7. Clostridium perfringens Type A Strains Carrying a Plasmid-Borne Enterotoxin Gene (Genotype IS1151-cpe or IS1470-like-cpe) as a Common Cause of Food Poisoning▿

    PubMed Central

    Lahti, Päivi; Heikinheimo, Annamari; Johansson, Tuula; Korkeala, Hannu

    2008-01-01

    The prevalences of various genotypes of enterotoxin gene-carrying (cpe-positive) Clostridium perfringens type A in 24 different food poisoning outbreaks were 75% (chromosomal IS1470-cpe), 21% (plasmid-borne IS1470-like-cpe), and 4% (plasmid-borne IS1151-cpe). These results show that C. perfringens type A carrying the plasmid-borne cpe is a common cause of food poisoning. PMID:18003798

  8. Surface Landing Site Weather Analysis for Constellation Program

    NASA Technical Reports Server (NTRS)

    Altino, Karen M.; Burns, K. Lee

    2008-01-01

    Weather information is an important asset for NASA's Constellation Program in developing the next generation space transportation system to fly to the International Space Station, the Moon and, eventually, to Mars. Weather conditions can affect vehicle safety and performance during multiple mission phases ranging from pre-launch ground processing to landing and recovery operations, including all potential abort scenarios. Meteorological analysis is an important contributor, not only to the development and verification of system design requirements but also to mission planning and active ground operations. Of particular interest are the surface atmospheric conditions at both nominal and abort landing sites for the manned Orion capsule. Weather parameters such as wind, rain, and fog all play critical roles in the safe landing of the vehicle and subsequent crew and vehicle recovery. The Marshall Space Flight Center Natural Environments Branch has been tasked by the Constellation Program with defining the natural environments at potential landing zones. Climatological time series of operational surface weather observations are used to calculate probabilities of occurrence of various sets of hypothetical vehicle constraint thresholds, Data are available for numerous geographical locations such that statistical analysis can be performed for single sites as well as multiple-site network configurations. Results provide statistical descriptions of how often certain weather conditions are observed at the site(s) and the percentage that specified criteria thresholds are matched or exceeded. Outputs are tabulated by month and hour of day to show both seasonal and diurnal variation. This paper will describe the methodology used for data collection and quality control, detail the types of analyses performed, and provide a sample of the results that can be obtained,

  9. 78 FR 5198 - Notice of Inventory Completion: University of Washington, Department of Anthropology, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ... Inventory Completion: University of Washington, Department of Anthropology, Seattle, WA AGENCY: National... Anthropology, has completed an inventory of human remains and associated funerary objects, in consultation with... of Washington, Department of Anthropology. Disposition of the human remains to the Indian tribes...

  10. 75 FR 41883 - Notice of Inventory Completion: Museum of Anthropology, Washington State University Pullman, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... Anthropology, Washington State University Pullman, WA AGENCY: National Park Service, Interior. ACTION: Notice... associated funerary objects in the possession and control of the Museum of Anthropology, Washington State... made by Museum of Anthropology, Washington State University, professional staff in consultation with...

  11. Reach for the Stars: A Constellational Approach to Ethnographies of Elite Schools

    ERIC Educational Resources Information Center

    Prosser, Howard

    2014-01-01

    This paper offers a method for examining elite schools in a global setting by appropriating Theodor Adorno's constellational approach. I contend that arranging ideas and themes in a non-deterministic fashion can illuminate the social reality of elite schools. Drawing on my own fieldwork at an elite school in Argentina, I suggest that local and…

  12. The Magnetospheric Constellation Mission. Dynamic Response and Coupling Observatory (DRACO): Understanding the Global Dynamics of the Structured Magnetotail

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Magnetospheric Constellation Dynamic Response and Coupling Observatory (DRACO) is the Solar Terrestrial Probe (STP) designed to understand the nonlinear dynamics, responses, and connections within the Earth's structured magnetotail, using a constellation of approximately 50 to 100 distributed vector measurement spacecraft. DRACO will reveal magnetotail processes operating within a domain extending 20 Earth radii (R(sub E)) across the tail and 40 R(sub E)down the tail, on spatial and time scales accessible to global circulation models, i.e., approximately 2 R(sub E) and 10 seconds.

  13. New Science Enabled by the NASA TROPICS CubeSat Constellation Mission

    NASA Astrophysics Data System (ADS)

    Blackwell, W. J.; Braun, S. A.; Bennartz, R.; Velden, C.; Demaria, M.; Atlas, R. M.; Dunion, J. P.; Marks, F.; Rogers, R. F.; Annane, B.

    2017-12-01

    Recent technology advances in miniature microwave radiometers that can be hosted on very small satellites has made possible a new class of affordable constellation missions that provide very high revisit rates of tropical cyclones and other severe weather. The Time-Resolved Observations of Precipitation structure and storm Intensity with a Constellation of Smallsats (TROPICS) mission was selected by NASA as part of the Earth Venture-Instrument (EVI-3) program and is now in development with planned launch readiness in late 2019. The overarching goal for TROPICS is to provide nearly all-weather observations of 3-D temperature and humidity, as well as cloud ice and precipitation horizontal structure, at high temporal resolution to conduct high-value science investigations of tropical cyclones, including: (1) relationships of rapidly evolving precipitation and upper cloud structures to upper-level warm-core intensity and associated storm intensity changes; (2) the evolution of precipitation structure and storm intensification in relationship to environmental humidity fields; and (3) the impact of rapid-update observations on numerical and statistical intensity forecasts of tropical cyclones. TROPICS will provide rapid-refresh microwave measurements (median refresh rate better than 60 minutes for the baseline mission) over the tropics that can be used to observe the thermodynamics of the troposphere and precipitation structure for storm systems at the mesoscale and synoptic scale over the entire storm lifecycle. TROPICS comprises a constellation of six CubeSats in three low-Earth orbital planes. Each CubeSat will host a high performance radiometer to provide temperature profiles using seven channels near the 118.75 GHz oxygen absorption line, water vapor profiles using 3 channels near the 183 GHz water vapor absorption line, imagery in a single channel near 90 GHz for precipitation measurements (when combined with higher resolution water vapor channels), and a single

  14. LinkImpute: Fast and Accurate Genotype Imputation for Nonmodel Organisms

    PubMed Central

    Money, Daniel; Gardner, Kyle; Migicovsky, Zoë; Schwaninger, Heidi; Zhong, Gan-Yuan; Myles, Sean

    2015-01-01

    Obtaining genome-wide genotype data from a set of individuals is the first step in many genomic studies, including genome-wide association and genomic selection. All genotyping methods suffer from some level of missing data, and genotype imputation can be used to fill in the missing data and improve the power of downstream analyses. Model organisms like human and cattle benefit from high-quality reference genomes and panels of reference genotypes that aid in imputation accuracy. In nonmodel organisms, however, genetic and physical maps often are either of poor quality or are completely absent, and there are no panels of reference genotypes available. There is therefore a need for imputation methods designed specifically for nonmodel organisms in which genomic resources are poorly developed and marker order is unreliable or unknown. Here we introduce LinkImpute, a software package based on a k-nearest neighbor genotype imputation method, LD-kNNi, which is designed for unordered markers. No physical or genetic maps are required, and it is designed to work on unphased genotype data from heterozygous species. It exploits the fact that markers useful for imputation often are not physically close to the missing genotype but rather distributed throughout the genome. Using genotyping-by-sequencing data from diverse and heterozygous accessions of apples, grapes, and maize, we compare LD-kNNi with several genotype imputation methods and show that LD-kNNi is fast, comparable in accuracy to the best-existing methods, and exhibits the least bias in allele frequency estimates. PMID:26377960

  15. LinkImpute: Fast and Accurate Genotype Imputation for Nonmodel Organisms.

    PubMed

    Money, Daniel; Gardner, Kyle; Migicovsky, Zoë; Schwaninger, Heidi; Zhong, Gan-Yuan; Myles, Sean

    2015-09-15

    Obtaining genome-wide genotype data from a set of individuals is the first step in many genomic studies, including genome-wide association and genomic selection. All genotyping methods suffer from some level of missing data, and genotype imputation can be used to fill in the missing data and improve the power of downstream analyses. Model organisms like human and cattle benefit from high-quality reference genomes and panels of reference genotypes that aid in imputation accuracy. In nonmodel organisms, however, genetic and physical maps often are either of poor quality or are completely absent, and there are no panels of reference genotypes available. There is therefore a need for imputation methods designed specifically for nonmodel organisms in which genomic resources are poorly developed and marker order is unreliable or unknown. Here we introduce LinkImpute, a software package based on a k-nearest neighbor genotype imputation method, LD-kNNi, which is designed for unordered markers. No physical or genetic maps are required, and it is designed to work on unphased genotype data from heterozygous species. It exploits the fact that markers useful for imputation often are not physically close to the missing genotype but rather distributed throughout the genome. Using genotyping-by-sequencing data from diverse and heterozygous accessions of apples, grapes, and maize, we compare LD-kNNi with several genotype imputation methods and show that LD-kNNi is fast, comparable in accuracy to the best-existing methods, and exhibits the least bias in allele frequency estimates. Copyright © 2015 Money et al.

  16. The data access infrastructure of the Wadden Sea Long Term Ecosystem Research (WaLTER) project

    NASA Astrophysics Data System (ADS)

    De Bruin, T.

    2011-12-01

    The Wadden Sea, North of The Netherlands, Germany and Danmark, is one of the most important tidal areas in the world. In 2009, the Wadden Sea was listed on the UNESCO World Heritage list. The area is noted for its ecological diversity and value, being a stopover for large numbers of migrating birds. The Wadden Sea is also used intensively for economic activities by inhabitants of the surrounding coasts and islands, as well as by the many tourists visiting the area every year. A whole series of monitoring programmes is carried out by a range of governmental bodies and institutes to study the natural processes occuring in the Wadden Sea ecosystems as well as the influence of human activities on those ecosystems. Yet, the monitoring programmes are scattered and it is difficult to get an overview of those monitoring activities or to get access to the data resulting from those monitoring programmes. The Wadden Sea Long Term Ecosystem Research (WaLTER) project aims to: 1. To provide a base set of consistent, standardized, long-term data on changes in the Wadden Sea ecological and socio-economic system in order to model and understand interrelationships with human use, climate variation and possible other drivers. 2. To provide a research infrastructure, open access to commonly shared databases, educational facilities and one or more field sites in which experimental, innovative and process-driven research can be carried out. This presentation will introduce the WaLTER-project and explain the rationale for this project. The presentation will focus on the data access infrastructure which will be used for WaLTER. This infrastructure is part of the existing and operational infrastructure of the National Oceanographic Data Committee (NODC) in the Netherlands. The NODC forms the Dutch node in the European SeaDataNet consortium, which has built an European, distributed data access infrastructure. WaLTER, NODC and SeaDataNet all use the same technology, developed within the Sea

  17. The More You Can Get the Better: Mentoring Constellations and Intrinsic Career Success

    ERIC Educational Resources Information Center

    van Emmerik, I. J. Jetty

    2004-01-01

    This study focused on the relationship between mentoring constellations and intrinsic career success. Hierarchical regression analyses on the data of 416 female and 594 male university members showed that mentoring was positively associated with intrinsic career success i.e., career satisfaction and intrinsic job satisfaction. Several…

  18. 78 FR 19297 - Notice of Inventory Completion: University of Washington, Department of Anthropology, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ...-PPWOCRADN0] Notice of Inventory Completion: University of Washington, Department of Anthropology, Seattle, WA..., Department of Anthropology, has completed an inventory of human remains and associated funerary objects, in... Burke Museum acting on behalf of the University of Washington, Department of Anthropology. Disposition...

  19. 78 FR 11673 - Notice of Inventory Completion: University of Washington, Department of Anthropology, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... Inventory Completion: University of Washington, Department of Anthropology, Seattle, WA AGENCY: National... Anthropology, has completed an inventory of human remains and associated funerary objects, in consultation with... Anthropology. Disposition of the human remains and associated funerary objects to the Indian tribes stated...

  20. 78 FR 25471 - Notice of Inventory Completion: University of Washington, Department of Anthropology, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ....R50000] Notice of Inventory Completion: University of Washington, Department of Anthropology, Seattle, WA..., Department of Anthropology, has completed an inventory of human remains and associated funerary objects, in... Burke Museum acting on behalf of the University of Washington, Department of Anthropology. Disposition...