ERIC Educational Resources Information Center
Edwards, Timothy I.; Roberson, Clarence E., Jr.
A survey of 470 graduates of the six engineering technology programs at Wake Technical Institute--Architectural, Chemical, Civil Engineering, Computer, Electronic Engineering, and Industrial Engineering Technologies--and 227 of their employers was conducted in October, 1979, to determine the science and mathematics topics most needed by…
The Effect of Flow Curvature on the Axisymmetric Wake
NASA Astrophysics Data System (ADS)
Holmes, Marlin; Naughton, Jonathan
2016-11-01
The swirling turbulent wake is a perturbation to the canonical axisymmetric turbulent wake. Past studies of the axisymmetric turbulent wake have increased understanding of wake Reynolds number influence on wake characteristics such as centerline wake velocity deficit and wake width. In comparison, the axisymmetric turbulent swirling wake has received little attention. Earlier work by our group has shown that the addition of swirl can change the characteristics of the wake. The goal of this current work is to examine how wake mean flow quantities are related to the wake Reynolds number and the swirl number, where the latter quantity is the ratio of the angular momentum flux to the axial momentum deficit flux. A custom designed swirling wake generator is used in a low turbulence intensity wind tunnel flow to study the turbulent swirling wake in isolation. Stereoscopic Particle Image Velocimetry is used to obtain three component velocity fields in the axial-radial plane. From this data, the wake Reynolds number, the swirl number, centerline velocity decay, wake width, and other relevant wake mean flow quantities are determined. Using these results, the impact of swirl on wake development is discussed. This work was supported by the U.S. Department of Energy, Office of Science, Basic Energy Sciences, under Award # DE-SC0012671.
The sleep-wake-cycle: basic mechanisms.
Jones, B E
1989-11-01
The physiologic characteristics of the sleep-wake states have been well defined and some of the chemical and neuron systems that participate in the cyclic generation and maintenance of these states have been identified. The actual dynamic process by which these systems interact to generate the basic sleep-wake cycle, however, remains a mystery.
Awakening is not a metaphor: the effects of Buddhist meditation practices on basic wakefulness
Britton, Willoughby B.; Lindahl, Jared R.; Cahn, B. Rael; Davis, Jake H.; Goldman, Roberta E.
2014-01-01
Buddhist meditation practices have become a topic of widespread interest in both science and medicine. Traditional Buddhist formulations describe meditation as a state of relaxed alertness that must guard against both excessive hyperarousal (restlessness) and excessive hypoarousal (drowsiness, sleep). Modern applications of meditation have emphasized the hypoarousing and relaxing effects without as much emphasis on the arousing or alertness-promoting effects. In an attempt to counterbalance the plethora of data demonstrating the relaxing and hypoarousing effects of Buddhist meditation, this interdisciplinary review aims to provide evidence of meditation’s arousing or wake-promoting effects by drawing both from Buddhist textual sources and from scientific studies, including subjective, behavioral, and neuroimaging studies during wakefulness, meditation, and sleep. Factors that may influence whether meditation increases or decreases arousal are discussed, with particular emphasis on dose, expertise, and contemplative trajectory. The course of meditative progress suggests a nonlinear multiphasic trajectory such that early phases that are more effortful may produce more fatigue and sleep propensity, while later stages produce greater wakefulness as a result of neuroplastic changes and more efficient processing. PMID:24372471
Cavitation noise studies on marine propellers
NASA Astrophysics Data System (ADS)
Sharma, S. D.; Mani, K.; Arakeri, V. H.
1990-04-01
Experimental observations are described of cavitation inception and noise from five model propellers, three basic and two modified, tested in the open jet section of the Indian Institute of Science high-speed water tunnel facility. Extensive experiments on the three basic propellers of different design, which included visualization of cavitation and measurements of noise, showed that the dominant type of cavitation was in the form of tip vortex cavitation, accompanied by leading edge suction side sheet cavitation in its close vicinity, and the resultant noise depended on parameters such as the advance coefficient, the cavitation number, and the propeller geometry. Of these, advance coefficient was found to have the maximum influence not only on cavitation noise but also on the inception of cavitation. Noise levels and frequencies of spectra obtained from all the three basic propellers at conditions near inception and different advance coefficient values, when plotted in the normalized form as suggested by Blake, resulted in a universal spectrum which would be useful for predicting cavitation noise at prototype scales when a limited extent of cavitation is expected in the same form as observed on the present models. In an attempt to delay the onset of tip vortex cavitation, the blades of two of the three basic propellers were modified by drilling small holes in the tip and leading edge areas. Studies on the modified propellers showed that the effectiveness of the blade modification was apparently stronger at low advance coefficient values and depended on the blade sectional profile. Measurements of cavitation noise indicated that the modification also improved the acoustic performance of the propellers as it resulted in a complete attenuation of the low-frequency spectral peaks, which were prominent with the basic propellers. In addition to the above studies, which were conducted under uniform flow conditions, one of the basic propellers was tested in the simulated wake of a typical single screw ship. The wake was simulated by using a wire screen technique. Observations of cavitation and measurement of noise clearly showed that the presence of the wake had a strong influence on the propeller cavitation and noise performance. Cavitation was found to be of the cloud type, which generated very intense noise compared to that generated by tip vortex cavitation along with leading edge suction side sheet cavitation in the uniform flow conditions. The noise spectra obtained with wake simulation also are presented in a normalized form to be of general utility.
Evaluation of Fast-Time Wake Vortex Prediction Models
NASA Technical Reports Server (NTRS)
Proctor, Fred H.; Hamilton, David W.
2009-01-01
Current fast-time wake models are reviewed and three basic types are defined. Predictions from several of the fast-time models are compared. Previous statistical evaluations of the APA-Sarpkaya and D2P fast-time models are discussed. Root Mean Square errors between fast-time model predictions and Lidar wake measurements are examined for a 24 hr period at Denver International Airport. Shortcomings in current methodology for evaluating wake errors are also discussed.
Simulation of wind turbine wakes using the actuator line technique
Sørensen, Jens N.; Mikkelsen, Robert F.; Henningson, Dan S.; Ivanell, Stefan; Sarmast, Sasan; Andersen, Søren J.
2015-01-01
The actuator line technique was introduced as a numerical tool to be employed in combination with large eddy simulations to enable the study of wakes and wake interaction in wind farms. The technique is today largely used for studying basic features of wakes as well as for making performance predictions of wind farms. In this paper, we give a short introduction to the wake problem and the actuator line methodology and present a study in which the technique is employed to determine the near-wake properties of wind turbines. The presented results include a comparison of experimental results of the wake characteristics of the flow around a three-bladed model wind turbine, the development of a simple analytical formula for determining the near-wake length behind a wind turbine and a detailed investigation of wake structures based on proper orthogonal decomposition analysis of numerically generated snapshots of the wake. PMID:25583862
Simulation of wind turbine wakes using the actuator line technique.
Sørensen, Jens N; Mikkelsen, Robert F; Henningson, Dan S; Ivanell, Stefan; Sarmast, Sasan; Andersen, Søren J
2015-02-28
The actuator line technique was introduced as a numerical tool to be employed in combination with large eddy simulations to enable the study of wakes and wake interaction in wind farms. The technique is today largely used for studying basic features of wakes as well as for making performance predictions of wind farms. In this paper, we give a short introduction to the wake problem and the actuator line methodology and present a study in which the technique is employed to determine the near-wake properties of wind turbines. The presented results include a comparison of experimental results of the wake characteristics of the flow around a three-bladed model wind turbine, the development of a simple analytical formula for determining the near-wake length behind a wind turbine and a detailed investigation of wake structures based on proper orthogonal decomposition analysis of numerically generated snapshots of the wake. © 2015 The Author(s) Published by the Royal Society. All rights reserved.
The Accidental Toxicologist: A Career in the Science of ...
This PowerPoint presentation is part of a Health Science Career fair for Wake County, NC high school students. The purpose is to familiarize students with careers in the health sciences and the education necessary to be eligible for those careers. This presentation is part of a Health Science Career fair for Wake County, NC high school students. The purpose is to familiarize students with careers in the health sciences and the education necessary to be eligible for those careers.
Tip Vortices of Isolated Wings and Helicopter Rotor Blades.
1987-12-01
root to tip, as expected due to the induced downwash of the tip vor- tex and wake vortex sheet. Although the three different tip-caps produce very...the inherent limitation of not being able to model the vortex wake with these equations, although the Euler formulation has in it the necessary...physics to model vorticity transport correctly. These equations basically lack the physical mecha- nism needed to generate the vortex wake . However, in
Review of Idealized Aircraft Wake Vortex Models
NASA Technical Reports Server (NTRS)
Ahmad, Nashat N.; Proctor, Fred H.; Duparcmeur, Fanny M. Limon; Jacob, Don
2014-01-01
Properties of three aircraft wake vortex models, Lamb-Oseen, Burnham-Hallock, and Proctor are reviewed. These idealized models are often used to initialize the aircraft wake vortex pair in large eddy simulations and in wake encounter hazard models, as well as to define matched filters for processing lidar observations of aircraft wake vortices. Basic parameters for each vortex model, such as peak tangential velocity and circulation strength as a function of vortex core radius size, are examined. The models are also compared using different vortex characterizations, such as the vorticity magnitude. Results of Euler and large eddy simulations are presented. The application of vortex models in the postprocessing of lidar observations is discussed.
NASA Technical Reports Server (NTRS)
Whitelaw, J. H.
2001-01-01
Partial Contents: The Effect of Aircraft Wake Vortex Separation on Air Transportation Capacity; The Pilots View of Wake Vortices - Capacity vs. Safety; Runway Capacity Constraints at Heathrow Airport; FAA's Research Strategy; Increasing Capacity by Wake Turbulence Avoidance Systems at Frankfurt/Main Airport; Improving Airport Capacity Using Vertical Flight; Recent Developments in Industrial Wake Vortex Research; Vortex Evolution and Characterization; PIV -Survey of the Vortex Wake Structure behind an Airbus A340 in a Towing Tank.
Wake County Public School System Design Guidelines.
ERIC Educational Resources Information Center
Wake County Public School System, Raleigh, NC.
The Wake County Public School System has published its guidelines for planning and design of functional, cost effective, and durable educational facilities that are attractive and enhance the students' educational experience. The guidelines present basic planning requirement and design criteria for the entire construction process, including: codes…
2015-10-01
amniotic Fluid Derived Stem Cells (AFS). PRINCIPAL INVESTIGATOR: Thomas L. Smith, PhD CONTRACTING ORGANIZATION: Wake Forest University Health Sciences...UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Wake Forest University Health Sciences Medical Center Boulevard Winston-Salem, NC 27157
NASA Astrophysics Data System (ADS)
Tobin, Nicolas; Chamorro, Leonardo P.
2018-03-01
The so-called wake-moment coefficient C˜h and lateral wake deflection of three-dimensional windbreaks are explored in the near and far wake. Wind-tunnel experiments were performed to study the functional dependence of C˜h with windbreak aspect ratio, incidence angle, and the ratio of the windbreak height and surface roughness (h /z0 ). Supported with the data, we also propose basic models for the wake deflection of the windbreak in the near and far fields. The near-wake model is based on momentum conservation considering the drag on the windbreak, whereas the far-wake counterpart is based on existing models for wakes behind surface-mounted obstacles. Results show that C˜h does not change with windbreak aspect ratios of 10 or greater; however, it may be lower for an aspect ratio of 5. C˜h is found to change roughly with the cosine of the incidence angle, and to depend strongly on h /z0 . The data broadly support the proposed wake-deflection models, though better predictions could be made with improved knowledge of the windbreak drag coefficient.
A new methodology for free wake analysis using curved vortex elements
NASA Technical Reports Server (NTRS)
Bliss, Donald B.; Teske, Milton E.; Quackenbush, Todd R.
1987-01-01
A method using curved vortex elements was developed for helicopter rotor free wake calculations. The Basic Curve Vortex Element (BCVE) is derived from the approximate Biot-Savart integration for a parabolic arc filament. When used in conjunction with a scheme to fit the elements along a vortex filament contour, this method has a significant advantage in overall accuracy and efficiency when compared to the traditional straight-line element approach. A theoretical and numerical analysis shows that free wake flows involving close interactions between filaments should utilize curved vortex elements in order to guarantee a consistent level of accuracy. The curved element method was implemented into a forward flight free wake analysis, featuring an adaptive far wake model that utilizes free wake information to extend the vortex filaments beyond the free wake regions. The curved vortex element free wake, coupled with this far wake model, exhibited rapid convergence, even in regions where the free wake and far wake turns are interlaced. Sample calculations are presented for tip vortex motion at various advance ratios for single and multiple blade rotors. Cross-flow plots reveal that the overall downstream wake flow resembles a trailing vortex pair. A preliminary assessment shows that the rotor downwash field is insensitive to element size, even for relatively large curved elements.
NASA Technical Reports Server (NTRS)
Hinton, David A.; Tatnall, Chris R.
1997-01-01
A significant effort is underway at NASA Langley to develop a system to provide dynamical aircraft wake vortex spacing criteria to Air Traffic Control (ATC). The system under development, the Aircraft Vortex Spacing System (AVOSS), combines the inputs of multiple subsystems to provide separation matrices with sufficient stability for use by ATC and sufficient monitoring to ensure safety. The subsystems include a meteorological subsystem, a wake behavior prediction subsystem, a wake sensor subsystem, and system integration and ATC interfaces. The proposed AVOSS is capable of using two factors, singly or in combination, for reducing in-trail spacing. These factors are wake vortex motion out of a predefined approach corridor and wake decay below a strength that is acceptable for encounter. Although basic research into the wake phenomena has historically used wake total circulation as a strength parameter, there is a requirement for a more specific strength definition that may be applied across multiple disciplines and teams to produce a real-time, automated system. This paper presents some of the limitations of previous applications of circulation to aircraft wake observations and describes the results of a preliminary effort to bound a spacing system strength definition.
Maglakelidze, N T; Chkhartishvili, E V; Mchedlidze, O M; Dzadzamiia, Sh Sh; Nachkebiia, N G
2012-03-01
Modification of brain muscarinic cholinergic system normal functioning can be considered as an appropriate strategy for the study of its role in sleep-wakefulness cycle basic mechanisms in general and in the course/maintenance of PS in particular. For this aim systemic application of muscarinic cholinoreceptors antagonists is significant because it gives possibility to modify functioning all of known five sub-types of muscarinic cholinoreceptors and to study the character of sleep disturbances in these conditions. Problem is very topical because the question about the intimate aspects of BMChS involvement in PS maintaining mechanisms still remains unsolved. In cats Atropine systemic administration was made once daily at 10:00 a.m. and continuous EEG registration of sleep-wakefulness cycle ultradian structure, lasting for 10 hour daily, was started immediately. In sum each animal received anti-muscarinic drugs for 12 times. Thereafter drug administrations were ceased and EEG registration of sleep-wakefulness cycle ultradian structure was continued during 10 consecutive days. On the basis of results obtained in these conditions we can conclude that brain muscarinic cholinergic system normal functioning is significant for basic mechanisms of sleep-wakefulness cycle. During wakefulness, at the level of neocortex and hippocampus, MChS supports only EEG activation, while it is one of the main factors in PS triggering and maintaining mechanisms.
2013-01-01
Background Clinical psychiatry has always been limited by the lack of objective tests to substantiate diagnoses and a lack of specific treatments that target underlying pathophysiology. One area in which these twin failures has been most frustrating is major depression. Due to very considerable progress in the basic and clinical neurosciences of sleep-wake cycles and underlying circadian systems this situation is now rapidly changing. Discussion The development of specific behavioral or pharmacological strategies that target these basic regulatory systems is driving renewed clinical interest. Here, we explore the extent to which objective tests of sleep-wake cycles and circadian function - namely, those that measure timing or synchrony of circadian-dependent physiology as well as daytime activity and nighttime sleep patterns - can be used to identify a sub-class of patients with major depression who have disturbed circadian profiles. Summary Once this unique pathophysiology is characterized, a highly personalized treatment plan can be proposed and monitored. New treatments will now be designed and old treatments re-evaluated on the basis of their effects on objective measures of sleep-wake cycles, circadian rhythms and related metabolic systems. PMID:23521808
Dynamics of sleep/wake determination--Normal and abnormal
NASA Astrophysics Data System (ADS)
Mahowald, Mark W.; Schenck, Carlos H.; O'Connor, Kevin A.
1991-10-01
Virtually all members of the animal kingdom experience a relentless and powerful cycling of states of being: wakefulness, rapid eye movement sleep, and nonrapid eye movement sleep. Each of these states is composed of a number of physiologic variables generated in a variety of neural structures. The predictable oscillations of these states are driven by presumed neural pacemakers which are entrained to the 24 h geophysical environment by the light/dark cycle. Experiments in nature have indicated that wake/sleep rhythm perturbations may occur either involving desynchronization of the basic 24 h wake/sleep cycle within the geophysical 24 h cycle (circadian rhythm disturbances) or involving the rapid oscillation or incomplete declaration of state (such as narcolepsy). The use of phase spaces to describe states of being may be of interest in the description of state determination in both illness and health. Some fascinating clinical and experimental phenomena may represent bifurcations in the sleep/wake control system.
Contrail Formation in Aircraft Wakes Using Large-Eddy Simulations
NASA Technical Reports Server (NTRS)
Paoli, R.; Helie, J.; Poinsot, T. J.; Ghosal, S.
2002-01-01
In this work we analyze the issue of the formation of condensation trails ("contrails") in the near-field of an aircraft wake. The basic configuration consists in an exhaust engine jet interacting with a wing-tip training vortex. The procedure adopted relies on a mixed Eulerian/Lagrangian two-phase flow approach; a simple micro-physics model for ice growth has been used to couple ice and vapor phases. Large eddy simulations have carried out at a realistic flight Reynolds number to evaluate the effects of turbulent mixing and wake vortex dynamics on ice-growth characteristics and vapor thermodynamic properties.
ERIC Educational Resources Information Center
Kirby, Matthew; Maggi, Stefania; D'Angiulli, Amedeo
2011-01-01
The authors have integrated the major findings on the sleep-wake cycle and its performance correlates in adolescents. Basic research shows that lack of synchronicity between early school start times and the circadian rhythm of adolescents (and the sleep debt accumulated as a result) involves several cognitive correlates that may harm the academic…
Space Flows and Disturbances Due to Bodies in Motion Through the Magnetoplasma
NASA Astrophysics Data System (ADS)
Ponomarjov, Maxim G.
2000-10-01
In this paper a method is concerned which makes it possible to describe numerically and analytically the most famous structures in the non-equilibrium ionosphere, such as stratified and yacht sail like structures, flute jets, wakes and clouds. These problems are of practical interest in space sciences, astrophysics and in turbulence theory, and also of fundamental interest since they enable one to concentrate on the effects of the ambient electric and magnetic fields. Disturbances of charged particle flows due to the ambient flow interactions with bodies are simulated with taking into account the ambient magnetic field effect. The effects of interactions between solid surfaces and the flows was simulated by making use of an original image method. The flow disturbances were described by the Boltzmann equation. In the case of the ambient homogeneous magnetic field the Boltzmann equation is solved analytically. The case of diffuse reflection of particles by surface is considered in detail. The disturbances of charged particle concentration are calculated in 3D space. The contours of constant particle concentration obtained from numerical simulations illustrate the dynamics of developing stratifications and flute structures in charged particle jets and wakes under the ambient magnetic field effect. The basic goal of this paper is to present the method and to demonstate its possibility for simulations of turbulence, plasma jets, wakes and clouds in the ionosphere and Space when effects of electric and magnetic fields are taken into account.
Method for Processing Liver Spheroids Using an Automatic Tissue Processor
2016-05-01
Harry; Kristovich, Robert L. (ECBC); and Valdes, Leah R. (ORISE) 5d. PROJECT NUMBER CRADA 1314C w/ Wake Forest University 5e. TASK NUMBER 5f. WORK...The work described in this report was authorized under project no. CRADA1314C with Wake Forest University Health Sciences. The work was started in... Wake Forest Institute for Regenerative Medicine Winston-Salem, NC iv Blank v CONTENTS 1. INTRODUCTION
The Roles of the Bone Marrow Microenvironment in Controlling Tumor Dormancy
2015-10-01
Shiozawa, M.D., Ph.D. CONTRACTING ORGANIZATION: Wake Forest School of Medicine Ann Arbor, MI 48109 REPORT DATE: October 2015 TYPE OF REPORT...PERFORMING ORGANIZATION REPORT NUMBER Wake Forest University Health Sciences Medical Center Blvd. Winston-Salem NC 27157 9. SPONSORING... Wake Forest School of Medicine as of 03/01/15. The PI obtained the necessary institutional approvals (IACUC, IRB, IBC) and submitted the grant
Pedunculopontine Gamma Band Activity and Development.
Garcia-Rill, Edgar; Luster, Brennon; Mahaffey, Susan; MacNicol, Melanie; Hyde, James R; D'Onofrio, Stasia M; Phillips, Cristy
2015-12-03
This review highlights the most important discovery in the reticular activating system in the last 10 years, the manifestation of gamma band activity in cells of the reticular activating system (RAS), especially in the pedunculopontine nucleus, which is in charge of waking and rapid eye movement (REM) sleep. The identification of different cell groups manifesting P/Q-type Ca(2+) channels that control waking vs. those that manifest N-type channels that control REM sleep provides novel avenues for the differential control of waking vs. REM sleep. Recent discoveries on the development of this system can help explain the developmental decrease in REM sleep and the basic rest-activity cycle.
Preliminary rotor wake measurements with a laser velocimeter
NASA Technical Reports Server (NTRS)
Hoad, D. R.; Rhodes, D. B.; Meyers, J. F.
1983-01-01
A laser velocimeter (LV) was used to determine rotor wake characteristics. The effect of various fuselage widths and rotor-fuselage spacings on time averaged and detailed time dependent rotor wake velocity characteristics was defined. Definition of time dependent velocity characteristics was attempted with the LV by associating a rotor azimuth position with each velocity measurement. Results were discouraging in that no apparent time dependent velocity characteristics could be discerned from the LV measurements. Since the LV is a relatively new instrument in the rotor wake measurement field, the cause of this lack of periodicity is as important as the basic research objectives. An attempt was made to identify the problem by simulated acquisition of LV-type data for a predicted rotor wake velocity time history. Power spectral density and autocorrelation function estimation techniques were used to substantiate the conclusion that the primary cause of the lack of time dependent velocity characteristics was the nonstationary flow condition generated by the periodic turbulence level that currently exists in the open throat configuration of the wind tunnel.
[Dream in the land of paradoxical sleep].
Pire, E; Herman, G; Cambron, L; Maquet, P; Poirrier, R
2008-01-01
Paradoxical sleep (PS or REM sleep) is traditionally a matter for neurophysiology, a science of the brain. Dream is associated with neuropsychology and sciences of the mind. The relationships between sleep and dream are better understood in the light of new methodologies in both domains, particularly those of basic neurosciences which elucidate the mechanisms underlying SP and functional imaging techniques. Data from these approaches are placed here in the perspective of rather old clinical observations in human cerebral lesions and in the phylogeny of vertebrates, in order to support a theory of dream. Dreams may be seen as a living marker of a cognitivo-emotional process, called here "eidictic process", involving posterior brain and limbic structures, keeping up during wakefulness, but subjected, at that time, to the leading role of a cognitivo-rational process, called here "thought process". The last one is of instrumental origin in human beings. It involves prefrontal cortices (executive tasks) and frontal/parietal cortices (attention) in the brain. Some clinical implications of the theory are illustrated.
Datta, Subimal; MacLean, Robert Ross
2007-01-01
At its most basic level, the function of mammalian sleep can be described as a restorative process of the brain and body; recently, however, progressive research has revealed a host of vital functions to which sleep is essential. Although many excellent reviews on sleep behavior have been published, none have incorporated contemporary studies examining the molecular mechanisms that govern the various stages of sleep. Utilizing a holistic approach, this review is focused on the basic mechanisms involved in the transition from wakefulness, initiation of sleep and the subsequent generation of slow-wave sleep and rapid eye movement (REM) sleep. Additionally, using recent molecular studies and experimental evidence that provides a direct link to sleep as a behavior, we have developed a new model, the Cellular-Molecular-Network model, explaining the mechanisms responsible for regulating REM sleep. By analyzing the fundamental neurobiological mechanisms responsible for the generation and maintenance of sleep-wake behavior in mammals, we intend to provide a broader understanding of our present knowledge in the field of sleep research. PMID:17445891
2015-09-01
Nerve Allografts plus amniotic Fluid Derived Stem Cells (AFS). PRINCIPAL INVESTIGATOR: Li, Zhongyu CONTRACTING ORGANIZATION: Wake Forest ...NUMBER: Wake Forest University Health Sciences Medical Center Boulevard Winston-Salem, NC 27157 9. SPONSORING / MONITORING AGENCY NAME(S) AND
Numerical investigations of wake interactions of two wind turbines in tandem
NASA Astrophysics Data System (ADS)
Qian, Yaoru; Wang, Tongguang
2018-05-01
Aerodynamic performance and wake interactions between two wind turbine models under different layouts are investigated numerically using large eddy simulation in conjunction with actuator line method based on the “Blind Test” series wind tunnel experiments from Norwegian University of Science and Technology. Numerical results of the power and thrust coefficients of the two rotors and wake characteristics are in good agreement with the experimental measurements. Extended investigations emphasizing the influence of different layout arrangements on the downstream rotor performance and wake development are conducted. Results show that layout arrangements have great influence on the power and thrust prediction of the downstream turbine.
Dopaminergic Modulation of Sleep-Wake States.
Herrera-Solis, Andrea; Herrera-Morales, Wendy; Nunez-Jaramillo, Luis; Arias-Carrion, Oscar
2017-01-01
The role of dopamine in sleep-wake regulation is considered as a wakefulness-promoting agent. For the clinical treatment of excessive daytime sleepiness, drugs have been commonly used to increase dopamine release. However, sleep disorders or lack of sleep are related to several dopaminerelated disorders. The effects of dopaminergic agents, nevertheless, are mediated by two families of dopamine receptors, D1 and D2-like receptors; the first family increases adenylyl cyclase activity and the second inhibits adenylyl cyclase. For this reason, the dopaminergic agonist effects on sleep-wake cycle are complex. Here, we review the state-of-the-art and discuss the different effects of dopaminergic agonists in sleep-wake states, and propose that these receptors account for the affinity, although not the specificity, of several effects on the sleep-wake cycle. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
NASA Technical Reports Server (NTRS)
Lewellen, D. C.; Lewellen, W. S.
2001-01-01
High-resolution numerical large-eddy simulations of the near wake of a B757 including simplified NOx and HOx chemistry were performed to explore the effects of dynamics on chemistry in wakes of ages from a few seconds to several minutes. Dilution plays an important basic role in the NOx-O3 chemistry in the wake, while a more interesting interaction between the chemistry and dynamics occurs for the HOx species. These simulation results are compared with published measurements of OH and HO2 within a B757 wake under cruise conditions in the upper troposphere taken during the Subsonic Aircraft Contrail and Cloud Effects Special Study (SUCCESS) mission in May 1996. The simulation provides a much finer grained representation of the chemistry and dynamics of the early wake than is possible from the 1 s data samples taken in situ. The comparison suggests that the previously reported discrepancy of up to a factor of 20 - 50 between the SUCCESS measurements of the [HO2]/[OH] ratio and that predicted by simplified theoretical computations is due to the combined effects of large mixing rates around the wake plume edges and averaging over volumes containing large species fluctuations. The results demonstrate the feasibility of using three-dimensional unsteady large-eddy simulations with coupled chemistry to study such phenomena.
Mikhail, Cyril; Vaucher, Angélique; Jimenez, Sonia; Tafti, Mehdi
2017-01-24
Wakefulness is accompanied by experience-dependent synaptic plasticity and an increase in activity-regulated gene transcription. Wake-induced genes are certainly markers of neuronal activity and may also directly regulate the duration of and need for sleep. We stimulated murine cortical cultures with the neuromodulatory signals that are known to control wakefulness in the brain and found that norepinephrine alone or a mixture of these neuromodulators induced activity-regulated gene transcription. Pharmacological inhibition of the various signaling pathways involved in the regulation of gene expression indicated that the extracellular signal-regulated kinase (ERK) pathway is the principal one mediating the effects of waking neuromodulators on gene expression. In mice, ERK phosphorylation in the cortex increased and decreased with wakefulness and sleep. Whole-body or cortical neuron-specific deletion of Erk1 or Erk2 significantly increased the duration of wakefulness in mice, and pharmacological inhibition of ERK phosphorylation decreased sleep duration and increased the duration of wakefulness bouts. Thus, this signaling pathway, which is highly conserved from Drosophila to mammals, is a key pathway that links waking experience-induced neuronal gene expression to sleep duration and quality. Copyright © 2017, American Association for the Advancement of Science.
The stability to two-dimensional wakes and shear layers at high Mach numbers
NASA Technical Reports Server (NTRS)
Papageorgiou, Demetrios T.
1991-01-01
This study is concerned with the stability properties of laminar free-shear-layer flows, and in particular symmetric two-dimensional wakes, for the supersonic through the hypersonic regimes. Emphasis is given to the use of proper wake profiles that satisfy the equations of motion at high Reynolds numbers. In particular the inviscid stability of a developing two-dimensional wake is studied as it accelerates at the trailing edge of a splitter plate. The nonparallelism of the flow is a leading-order effect in the calculation of the basic state, which is obtained numerically. Neutral stability characteristics are computed and the hypersonic stability is obtained by increasing the Mach number. It is found that the stability characteristics are altered significantly as the wake develops. Multiple modes (secondary modes) are found in the near wake that are closely related to the corresponding Blasius ones, but as the wake develops mode multiplicity is delayed to higher and higher Mach numbers. At a distance of about one plate length from the trailing edge, there is only one mode in a Mach number range of 0-20. The dominant mode emerging at all wake stations, and for high enough Mach numbers, is the so-called vorticity mode that is centered around the generalized inflection point layer. The structure of the dominant mode is also obtained analytically for all streamwise wake locations and it is shown how the far-wake limit is approached. Asymptotic results for the hypersonic mixing layer given by a tanh and a Lock distribution are also given.
NASA Technical Reports Server (NTRS)
Tatnall, Chistopher R.
1998-01-01
The counter-rotating pair of wake vortices shed by flying aircraft can pose a threat to ensuing aircraft, particularly on landing approach. To allow adequate time for the vortices to disperse/decay, landing aircraft are required to maintain certain fixed separation distances. The Aircraft Vortex Spacing System (AVOSS), under development at NASA, is designed to prescribe safe aircraft landing approach separation distances appropriate to the ambient weather conditions. A key component of the AVOSS is a ground sensor, to ensure, safety by making wake observations to verify predicted behavior. This task requires knowledge of a flowfield strength metric which gauges the severity of disturbance an encountering aircraft could potentially experience. Several proposed strength metric concepts are defined and evaluated for various combinations of metric parameters and sensor line-of-sight elevation angles. Representative populations of generating and following aircraft types are selected, and their associated wake flowfields are modeled using various wake geometry definitions. Strength metric candidates are then rated and compared based on the correspondence of their computed values to associated aircraft response values, using basic statistical analyses.
Brain Basics: Understanding Sleep
... slow, and muscles relax even further. Your body temperature drops and eye movements stop. Brain wave activity ... functions from daily fluctuations in wakefulness to body temperature, metabolism, and the release of hormones. They control ...
NASA Technical Reports Server (NTRS)
Wiehle, S.; Plaschke, F.; Motschmann, U.; Glassmeier, K. H.; Auster, H. U.; Angelopoulos, V.; Mueller, J.; Kriegel, H.; Georgescu, E.; Halekas, J.;
2011-01-01
The spacecraft P1 of the new ARTEMIS (Acceleration, Reconnection, Turbulence, and Electrodynamics of the Moon's Interaction with the Sun) mission passed the lunar wake for the first time on February 13, 2010. We present magnetic field and plasma data of this event and results of 3D hybrid simulations. As the solar wind magnetic field was highly dynamic during the passage, a simulation with stationary solar wind input cannot distinguish whether distortions were caused by these solar wind variations or by the lunar wake; therefore, a dynamic real-time simulation of the flyby has been performed. The input values of this simulation are taken from NASA OMNI data and adapted to the P1 data, resulting in a good agreement between simulation and measurements. Combined with the stationary simulation showing non-transient lunar wake structures, a separation of solar wind and wake effects is achieved. An anisotropy in the magnitude of the plasma bulk flow velocity caused by a non-vanishing magnetic field component parallel to the solar wind flow and perturbations created by counterstreaming ions in the lunar wake are observed in data and simulations. The simulations help to interpret the data granting us the opportunity to examine the entire lunar plasma environment and, thus, extending the possibilities of measurements alone: A comparison of a simulation cross section to theoretical predictions of MHD wave propagation shows that all three basic MHD modes are present in the lunar wake and that their expansion governs the lunar wake refilling process.
Euler equation computations for the flow over a hovering helicopter rotor
NASA Technical Reports Server (NTRS)
Roberts, Thomas Wesley
1988-01-01
A numerical solution technique is developed for computing the flow field around an isolated helicopter rotor in hover. The flow is governed by the compressible Euler equations which are integrated using a finite volume approach. The Euler equations are coupled to a free wake model of the rotary wing vortical wake. This wake model is incorporated into the finite volume solver using a prescribed flow, or perturbation, technique which eliminates the numerical diffusion of vorticity due to the artificial viscosity of the scheme. The work is divided into three major parts: (1) comparisons of Euler solutions to experimental data for the flow around isolated wings show good agreement with the surface pressures, but poor agreement with the vortical wake structure; (2) the perturbation method is developed and used to compute the interaction of a streamwise vortex with a semispan wing. The rapid diffusion of the vortex when only the basic Euler solver is used is illustrated, and excellent agreement with experimental section lift coefficients is demonstrated when using the perturbation approach; and (3) the free wake solution technique is described and the coupling of the wake to the Euler solver for an isolated rotor is presented. Comparisons with experimental blade load data for several cases show good agreement, with discrepancies largely attributable to the neglect of viscous effects. The computed wake geometries agree less well with experiment, the primary difference being that too rapid a wake contraction is predicted for all the cases.
Analysis of a high brightness photo electron beam with self field and wake field effects
DOE Office of Scientific and Technical Information (OSTI.GOV)
Parsa, Z.
High brightness sources are the basic ingredients in the new accelerator developments such as Free-Electron Laser experiments. The effects of the interactions between the highly charged particles and the fields in the accelerating structure, e.g. R.F., Space charge and Wake fields can be detrimental to the beam and the experiments. We present and discuss the formulation used, some simulation and results for the Brookhaven National Laboratory high brightness beam that illustrates effects of the accelerating field, space charge forces (e.g. due to self field of the bunch), and the wake field (e.g. arising from the interaction of the cavity surfacemore » and the self field of the bunch).« less
Clinical Pharmacology in Sleep Medicine
Proctor, Ashley; Bianchi, Matt T.
2012-01-01
The basic treatment goals of pharmacological therapies in sleep medicine are to improve waking function by either improving sleep or by increasing energy during wakefulness. Stimulants to improve waking function include amphetamine derivatives, modafinil, and caffeine. Sleep aids encompass several classes, from benzodiazepine hypnotics to over-the-counter antihistamines. Other medications used in sleep medicine include those initially used in other disorders, such as epilepsy, Parkinson's disease, and psychiatric disorders. As these medications are prescribed or encountered by providers in diverse fields of medicine, it is important to recognize the distribution of adverse effects, drug interaction profiles, metabolism, and cytochrome substrate activity. In this paper, we review the pharmacological armamentarium in the field of sleep medicine to provide a framework for risk-benefit considerations in clinical practice. PMID:23213564
Exploratory behavior, cortical BDNF expression, and sleep homeostasis.
Huber, Reto; Tononi, Giulio; Cirelli, Chiara
2007-02-01
Slow-wave activity (SWA; 0.5-4.0 Hz) during non-rapid eye movement (NREM) sleep is a reliable indicator of sleep need, as it increases with the duration of prior wakefulness and decreases during sleep. However, which biologic process occurring during wakefulness is responsible for the increase of sleep SWA remains unknown. The aim of the study was to determine whether neuronal plasticity underlies the link between waking activities and the SWA response. We manipulated, in rats, the amount of exploratory activity while maintaining the total duration of waking constant. We then measured the extent to which exploration increases cortical expression of plasticity-related genes (BDNF, Arc, Homer, NGFI-A), and the SWA response once the animals were allowed to sleep. Basic neurophysiology and molecular laboratory. Male Wistar Kyoto rats (250-300 g; 2-3 month old). None. We found that, within the same animal, the amount of exploratory behavior during wakefulness could predict the extent to which BDNF was induced, as well as the extent of the homeostatic SWA response during subsequent sleep. This study suggests a direct link between the synaptic plasticity triggered by waking activities and the homeostatic sleep response and identifies BDNF as a major mediator of this link at the molecular level.
Igniting and Sustaining Interest among Students Who Have Grown Cold toward Science
ERIC Educational Resources Information Center
Jack, Brady Michael; Lin, Huann-Shyang
2014-01-01
In the wake of interest-study research in science education over the past 10 years, investigators have published many articles on how to define, measure, and develop students' interest in learning science. This present study approaches empirical investigations on students' interest in learning science from a different perspective. We…
Iowa Test of Basic Skills, 2000-2001. Measuring Up. E&R Report.
ERIC Educational Resources Information Center
Tyler, Doris
In the Wake County Public School System (WCPSS), North Carolina, the Iowa Test of Basic Skills (ITBS) is administered to all third grade students each year. The ITBS, which is one of the assessments used as a screening tool for the Academically Gifted Program, was given to approximately 7,700 third graders in 2000. The ITBS can be given as a…
THE DEVELOPMENT OF SLEEP-WAKE RHYTHMS AND THE SEARCH FOR ELEMENTAL CIRCUITS IN THE INFANT BRAIN
Blumberg, Mark S.; Gall, Andrew J.; Todd, William D.
2014-01-01
Despite the predominance of sleep in early infancy, developmental science has yet to play a major role in shaping concepts and theories about sleep and its associated ultradian and circadian rhythms. Here we argue that developmental analyses help us to elucidate the relative contributions of the brainstem and forebrain to sleep-wake control and to dissect the neural components of sleep-wake rhythms. Developmental analysis also makes it clear that sleep-wake processes in infants are the foundation for those of adults. For example, the infant brainstem alone contains a fundamental sleep-wake circuit that is sufficient to produce transitions among wakefulness, quiet sleep, and active sleep. Also, consistent with the requirements of a “flip-flop” model of sleep-wake processes, this brainstem circuit supports rapid transitions between states. Later in development, strengthening bidirectional interactions between the brainstem and forebrain contribute to the consolidation of sleep and wake bouts, the elaboration of sleep homeostatic processes, and the emergence of diurnal or nocturnal circadian rhythms. The developmental perspective promoted here critically constrains theories of sleep-wake control and provides a needed framework for the creation of fully realized computational models. Finally, with a better understanding of how this system is constructed developmentally, we will gain insight into the processes that govern its disintegration due to aging and disease. PMID:24708298
The development of sleep-wake rhythms and the search for elemental circuits in the infant brain.
Blumberg, Mark S; Gall, Andrew J; Todd, William D
2014-06-01
Despite the predominance of sleep in early infancy, developmental science has yet to play a major role in shaping concepts and theories about sleep and its associated ultradian and circadian rhythms. Here we argue that developmental analyses help us to elucidate the relative contributions of the brainstem and forebrain to sleep-wake control and to dissect the neural components of sleep-wake rhythms. Developmental analysis also makes it clear that sleep-wake processes in infants are the foundation for those of adults. For example, the infant brainstem alone contains a fundamental sleep-wake circuit that is sufficient to produce transitions among wakefulness, quiet sleep, and active sleep. In addition, consistent with the requirements of a "flip-flop" model of sleep-wake processes, this brainstem circuit supports rapid transitions between states. Later in development, strengthening bidirectional interactions between the brainstem and forebrain contribute to the consolidation of sleep and wake bouts, the elaboration of sleep homeostatic processes, and the emergence of diurnal or nocturnal circadian rhythms. The developmental perspective promoted here critically constrains theories of sleep-wake control and provides a needed framework for the creation of fully realized computational models. Finally, with a better understanding of how this system is constructed developmentally, we will gain insight into the processes that govern its disintegration due to aging and disease.
ERIC Educational Resources Information Center
Lunde, Paul; And Others
1986-01-01
In the wake of the first space voyage and in-flight experiments by a Muslim astronaut, this document focuses upon the story of Islamic science through the ages. It is intended to demonstrate the resurgence of scientific research and technological development in the Muslim world. The booklet contains chapters on: (1) science: the Islamic legacy;…
Free wake analysis of hover performance using a new influence coefficient method
NASA Technical Reports Server (NTRS)
Quackenbush, Todd R.; Bliss, Donald B.; Ong, Ching Cho; Ching, Cho Ong
1990-01-01
A new approach to the prediction of helicopter rotor performance using a free wake analysis was developed. This new method uses a relaxation process that does not suffer from the convergence problems associated with previous time marching simulations. This wake relaxation procedure was coupled to a vortex-lattice, lifting surface loads analysis to produce a novel, self contained performance prediction code: EHPIC (Evaluation of Helicopter Performance using Influence Coefficients). The major technical features of the EHPIC code are described and a substantial amount of background information on the capabilities and proper operation of the code is supplied. Sample problems were undertaken to demonstrate the robustness and flexibility of the basic approach. Also, a performance correlation study was carried out to establish the breadth of applicability of the code, with very favorable results.
NASA Technical Reports Server (NTRS)
Hanson, D. B.
1991-01-01
A unified theory for the aerodynamics and noise of advanced turboprops are presented. Aerodynamic topics include calculation of performance, blade load distribution, and non-uniform wake flow fields. Blade loading can be steady or unsteady due to fixed distortion, counter-rotating wakes, or blade vibration. The aerodynamic theory is based on the pressure potential method and is therefore basically linear. However, nonlinear effects associated with finite axial induction and blade vortex flow are included via approximate methods. Acoustic topics include radiation of noise caused by blade thickness, steady loading (including vortex lift), and unsteady loading. Shielding of the fuselage by its boundary layer and the wing are treated in separate analyses that are compatible but not integrated with the aeroacoustic theory for rotating blades.
Vortex Wakes of Conventional Aircraft
1975-05-01
Research Laboratories, Wright-Patterson Air Force Base , Ohio 45433, USA This work was prepared at the request of the Fluid Dynamics Panel of AGARD. THE...aerospace sciences relevant to strengthening the common defence posture; - Improving the co-operation among member nations in aerospace research and...two models have been developed to describe the inviscid structure of the vortex wake. The first model was due to Prandtl [10] and is based on the
What physicians need to know about dreams and dreaming.
Pagel, James F
2012-11-01
An overview of the current status of dream science is given, designed to provide a basic background of this field for the sleep-interested physician. No cognitive state has been more extensively studied and is yet more misunderstood than dreaming. Much older work is methodologically limited by lack of definitions, small sample size, and constraints of theoretical perspective, with evidence equivocal as to whether any special relationship exists between rapid eye movement (REM) sleep and dreaming. As the relationship between dreams and REM sleep is so poorly defined, evidence-based studies of dreaming require a dream report. The different aspects of dreaming that can be studied include dream and nightmare recall frequency, dream content, dreaming effect on waking behaviors, dream/nightmare associated medications, and pathophysiology affecting dreaming. Whether studied from behavioral, neuroanatomical, neurochemical, pathophysiological or electrophysiological perspectives, dreaming reveals itself to be a complex cognitive state affected by a wide variety of medical, psychological, sleep and social variables.
Saper, Clifford B; Fuller, Patrick M; Pedersen, Nigel P; Lu, Jun; Scammell, Thomas E
2010-12-22
We take for granted the ability to fall asleep or to snap out of sleep into wakefulness, but these changes in behavioral state require specific switching mechanisms in the brain that allow well-defined state transitions. In this review, we examine the basic circuitry underlying the regulation of sleep and wakefulness and discuss a theoretical framework wherein the interactions between reciprocal neuronal circuits enable relatively rapid and complete state transitions. We also review how homeostatic, circadian, and allostatic drives help regulate sleep state switching and discuss how breakdown of the switching mechanism may contribute to sleep disorders such as narcolepsy. Copyright © 2010 Elsevier Inc. All rights reserved.
Saper, Clifford B.; Fuller, Patrick M.; Pedersen, Nigel P.; Lu, Jun; Scammell, Thomas E.
2010-01-01
We take for granted the ability to fall asleep or to snap out of sleep into wakefulness, but these changes in behavioral state require specific switching mechanisms in the brain that allow well-defined state transitions. In this review, we examine the basic circuitry underlying the regulation of sleep and wakefulness, and discuss a theoretical framework wherein the interactions between reciprocal neuronal circuits enable relatively rapid and complete state transitions. We also review how homeostatic, circadian, and allostatic drives help regulate sleep state switching, and discuss how breakdown of the switching mechanism may contribute to sleep disorders such as narcolepsy. PMID:21172606
A Wake-Up Call for U.S. Educators: The Third International Mathematics and Science Study.
ERIC Educational Resources Information Center
Cochrane, Douglas
1999-01-01
This issue of "Policy Forum" compares the mathematics and science achievement of students midway through elementary school, midway through lower secondary school, and at the end of upper secondary school. The Third International Mathematics and Science Study (TIMSS), conducted in 1995-96, is the largest international education study ever…
Miller, Nita Lewis; Tvaryanas, Anthony P.; Shattuck, Lawrence G.
2012-01-01
Study Objective: This study evaluated the effect of accommodating adolescent sleep-wake patterns by altering the timing of the major sleep period of US Army recruits. Design: The quasi-experimental study compared recruits assigned to one of two training companies: one with a customary sleep regimen (20:30 to 04:30) while the other employed a phase-delayed sleep regimen (23:00 to 07:00), the latter aligning better with biologically driven sleep-wake patterns of adolescents. Setting: The study was conducted during Basic Combat Training (BCT) at Fort Leonard Wood, Missouri. Trainees: The study included 392 trainees: 209 received the intervention, while 183 composed the Comparison group. Measurements and Results: Demographic and psychophysiological measures were collected on all trainees. Weekly assessments of subjective fatigue and mood, periodic physical fitness, marksmanship scores, and attrition rates from BCT were studied. Actigraphy was collected on approximately 24% of trainees. Based on actigraphy, trainees on the phase-delayed sleep schedule obtained 31 m more sleep/night than trainees on the customary sleep schedule. The Intervention group reported less total mood disturbance relative to baseline. Improvements in marksmanship correlated positively with average nightly sleep during the preceding week when basic marksmanship skills were taught. No differences were seen in physical fitness or attrition rates. In contrast to the Intervention group, the Comparison group was 2.3 times more likely to experience occupationally significant fatigue and 5.5 times more likely to report poor sleep quality. Conclusions: Accommodating adolescent sleep patterns significantly improves mental health and performance in the training environment. Citation: Miller NL; Tvaryanas AP; Shattuck LG. Accommodating adolescent sleep-wake patterns: the effects of shifting the timing of sleep on training effectiveness. SLEEP 2012;35(8):1123-1136. PMID:22851808
Hypersonic merged layer blunt body flows with wakes
NASA Technical Reports Server (NTRS)
Jain, Amolak C.; Dahm, Werner K.
1991-01-01
An attempt is made here to understand the basic physics of the flowfield with wake on a blunt body of revolution under hypersonic rarefied conditions. A merged layer model of flow is envisioned. Full steady-state Navier-Stokes equations in spherical polar coordinate system are computed from the surface with slip and temperature jump conditions to the free stream by the Accelerated Successive Replacement method of numerical integration. Analysis is developed for bodies of arbitrary shape, but actual computations have been carried out for a sphere and sphere-cone body. Particular attention is paid to set the limit of the onset of separation, wake closure, shear-layer impingement, formation and dissipation of the shocks in the flowfield. Validity of the results is established by comparing the present results for sphere with the corresponding results of the SOFIA code in the common region of their validity and with the experimental data.
Supersonic nonlinear potential analysis
NASA Technical Reports Server (NTRS)
Siclari, M. J.
1984-01-01
The NCOREL computer code was established to compute supersonic flow fields of wings and bodies. The method encompasses an implicit finite difference transonic relaxation method to solve the full potential equation in a spherical coordinate system. Two basic topic to broaden the applicability and usefulness of the present method which is encompassed within the computer code NCOREL for the treatment of supersonic flow problems were studied. The first topic is that of computing efficiency. Accelerated schemes are in use for transonic flow problems. One such scheme is the approximate factorization (AF) method and an AF scheme to the supersonic flow problem is developed. The second topic is the computation of wake flows. The proper modeling of wake flows is important for multicomponent configurations such as wing-body and multiple lifting surfaces where the wake of one lifting surface has a pronounced effect on a downstream body or other lifting surfaces.
NASA Technical Reports Server (NTRS)
Jenkins, Luther N.; Yao, Chung-Sheng; Bartram, Scott M.; Harris, Jerome; Allan, Brian; Wong, Oliver; Mace, W. Derry
2009-01-01
A Large Field-of-View Particle Image Velocimetry (LFPIV) system has been developed for rotor wake diagnostics in the 14-by 22-Foot Subsonic Tunnel. The system has been used to measure three components of velocity in a plane as large as 1.524 meters by 0.914 meters in both forward flight and hover tests. Overall, the system performance has exceeded design expectations in terms of accuracy and efficiency. Measurements synchronized with the rotor position during forward flight and hover tests have shown that the system is able to capture the complex interaction of the body and rotor wakes as well as basic details of the blade tip vortex at several wake ages. Measurements obtained with traditional techniques such as multi-hole pressure probes, Laser Doppler Velocimetry (LDV), and 2D Particle Image Velocimetry (PIV) show good agreement with LFPIV measurements.
Ultrastructural evidence for synaptic scaling across the wake/sleep cycle.
de Vivo, Luisa; Bellesi, Michele; Marshall, William; Bushong, Eric A; Ellisman, Mark H; Tononi, Giulio; Cirelli, Chiara
2017-02-03
It is assumed that synaptic strengthening and weakening balance throughout learning to avoid runaway potentiation and memory interference. However, energetic and informational considerations suggest that potentiation should occur primarily during wake, when animals learn, and depression should occur during sleep. We measured 6920 synapses in mouse motor and sensory cortices using three-dimensional electron microscopy. The axon-spine interface (ASI) decreased ~18% after sleep compared with wake. This decrease was proportional to ASI size, which is indicative of scaling. Scaling was selective, sparing synapses that were large and lacked recycling endosomes. Similar scaling occurred for spine head volume, suggesting a distinction between weaker, more plastic synapses (~80%) and stronger, more stable synapses. These results support the hypothesis that a core function of sleep is to renormalize overall synaptic strength increased by wake. Copyright © 2017, American Association for the Advancement of Science.
Basic Guidelines for University-Industry Research Relationships.
ERIC Educational Resources Information Center
Brannock, Jean C.; Denny, Amanda M.
1998-01-01
Universities should embrace university/industry relationships because they benefit both the institution and society. As such relationships evolve, the university should continually review its policies. The model used by Wake Forest University (North Carolina) for routinely reviewing research agreements is presented to assist other universities in…
Defense.gov Special Report: U.S. Military Responds in Wake of Earthquake
held the rank of airman basic, was lost on the streets of Tokyo. Story U.S. Forces Safe After New Japan transitioned through Seattle-Tacoma International Airport to safe-haven locations in the United States in March
NASA Astrophysics Data System (ADS)
Howland, Michael; Bossuyt, Juliaan; Kang, Justin; Meyers, Johan; Meneveau, Charles
2016-11-01
Reducing wake losses in wind farms by deflecting the wakes through turbine yawing has been shown to be a feasible wind farm control approach. In this work, the deflection and morphology of wakes behind a wind turbine operating in yawed conditions are studied using wind tunnel experiments of a wind turbine modeled as a porous disk in a uniform inflow. First, by measuring velocity distributions at various downstream positions and comparing with prior studies, we confirm that the nonrotating wind turbine model in yaw generates realistic wake deflections. Second, we characterize the wake shape and make observations of what is termed a "curled wake," displaying significant spanwise asymmetry. Through the use of a 100 porous disk micro-wind farm, total wind farm power output is studied for a variety of yaw configurations. Strain gages on the tower of the porous disk models are used to measure the thrust force as a substitute for turbine power. The frequency response of these measurements goes up to the natural frequency of the model and allows studying the spatiotemporal characteristics of the power output under the effects of yawing. This work has been funded by the National Science Foundation (Grants CBET-113380 and IIA-1243482, the WINDINSPIRE project). JB and JM are supported by ERC (ActiveWindFarms, Grant No. 306471).
Producing Turbulent Wind Tunnel Inflows Relevant to Wind Turbines using an Active Grid
NASA Astrophysics Data System (ADS)
Rumple, Christopher; Welch, Matthew; Naughton, Jonathan
2017-11-01
The rise of industries like wind energy have provided motivation for generating realistic turbulent inflows in wind tunnels. Facilities with the ability to produce such inflows can study the interaction between the inflow turbulence and the flow of interest such as a wind turbine wake. An active grid - a system of actively driven elements - has gained increasing acceptance in turbulence research over the last 20 years. The ability to tailor the inflow turbulence quantities (e.g. turbulence intensities, integral length scale, and turbulence spectrum) is a driving reason for the growing use of active grids. An active grid with 40 independent axes located within the forward contraction of a low speed wind tunnel is used to explore the range of turbulent inflows possible using hot-wire anemometry to characterize the turbulence. Motor control algorithms (i.e. user waveform inputs) used to produce various turbulent inflows will be presented. Wind data available from meteorological towers are used to develop relevant inflows for wind turbines to demonstrate the usefulness of the active grid. This work was supported by the U.S. Department of Energy, Office of Science, Basic Energy Sciences, under Award # DE-SC0012671.
An Introduction to Turbulent Flow
NASA Astrophysics Data System (ADS)
Mathieu, Jean; Scott, Julian
2000-06-01
In recent years, turbulence has become a very lively area of scientific research and application, attracting many newcomers who need a basic introduction to the subject. Turbulent Flows ably meets this need, developing both physical insight and the mathematical framework needed to express the theory. The authors present basic theory and illustrate it with examples of simple turbulent flows and classical models of jets, wakes, and boundary layers. A deeper understanding of turbulence dynamics is provided by their treatment of spectral analysis and its applications.
NASA Astrophysics Data System (ADS)
Olson, David; Naguib, Ahmed; Koochesfahani, Manoochehr
2017-11-01
Many of the natural flyers have deformable wing structures and exhibit complex kinematics in order to produce lift and thrust. Replicating all of these conditions in the laboratory (or in simulations) is extremely difficult, and drawing explicit connections to basic unsteady aerodynamics models and theories is even more complicated. Therefore, simplified wing structure and kinematics are typically used to facilitate drawing out these connections. In this work, measurements are conducted using a rigid and a chordwise-flexible NACA 0009 airfoils when harmonically pitched about the quarter chord point. Molecular tagging velocimetry is used to characterize the wake and estimate the thrust based on the momentum integral equation as function of the reduced frequency and the pitching amplitude. The results obtained using the two different airfoils are compared in order to examine the influence of structural flexibility. Consistent with the literature, chordwise flexibility is found to enhance thrust production and the circulation of the vortices shed into the wake, for a certain range of frequencies and amplitudes. Additional characterizations are undertaken of the wake vortex structure and its scaling. This work was supported by AFOSR Award Number FA9550-10-1-0342.
Dynamic Hybrid Simulation of the Lunar Wake During ARTEMIS Crossing
NASA Astrophysics Data System (ADS)
Wiehle, S.; Plaschke, F.; Angelopoulos, V.; Auster, H.; Glassmeier, K.; Kriegel, H.; Motschmann, U. M.; Mueller, J.
2010-12-01
The interaction of the highly dynamic solar wind with the Moon is simulated with the A.I.K.E.F. (Adaptive Ion Kinetic Electron Fluid) code for the ARTEMIS P1 flyby on February 13, 2010. The A.I.K.E.F. hybrid plasma simulation code is the improved version of the Braunschweig code. It is able to automatically increase simulation grid resolution in areas of interest during runtime, which greatly increases resolution as well as performance. As the Moon has no intrinsic magnetic field and no ionosphere, the solar wind particles are absorbed at its surface, resulting in the formation of the lunar wake at the nightside. The solar wind magnetic field is basically convected through the Moon and the wake is slowly filled up with solar wind particles. However, this interaction is strongly influenced by the highly dynamic solar wind during the flyby. This is considered by a dynamic variation of the upstream conditions in the simulation using OMNI solar wind measurement data. By this method, a very good agreement between simulation and observations is achieved. The simulations show that the stationary structure of the lunar wake constitutes a tableau vivant in space representing the well-known Friedrichs diagram for MHD waves.
Dash, Michael B; Tononi, Giulio; Cirelli, Chiara
2012-07-01
It is well established that brain metabolism is higher during wake and rapid eye movement (REM) sleep than in nonrapid eye movement (NREM) sleep. Most of the brain's energy is used to maintain neuronal firing and glutamatergic transmission. Recent evidence shows that cortical firing rates, extracellular glutamate levels, and markers of excitatory synaptic strength increase with time spent awake and decline throughout NREM sleep. These data imply that the metabolic cost of each behavioral state is not fixed but may reflect sleep-wake history, a possibility that is investigated in the current report. Chronic (4d) electroencephalographic (EEG) recordings in the rat cerebral cortex were coupled with fixed-potential amperometry to monitor the extracellular concentration of oxygen ([oxy]) and lactate ([lac]) on a second-by-second basis across the spontaneous sleep-wake cycle and in response to sleep deprivation. Basic sleep research laboratory. Wistar Kyoto (WKY) adult male rats. N/A. Within 30-60 sec [lac] and [oxy] progressively increased during wake and REM sleep and declined during NREM sleep (n = 10 rats/metabolite), but with several differences. [Oxy], but not [lac], increased more during wake with high motor activity and/or elevated EEG high-frequency power. Meanwhile, only the NREM decline of [lac] reflected sleep pressure as measured by slow-wave activity, mirroring previous results for cortical glutamate. The observed state-dependent changes in cortical [lac] and [oxy] are consistent with higher brain metabolism during waking and REM sleep in comparison with NREM sleep. Moreover, these data suggest that glycolytic activity, most likely through its link with glutamatergic transmission, reflects sleep homeostasis.
NASA Astrophysics Data System (ADS)
Ciszak, Marzena; Bellesi, Michele
2011-12-01
The transitions between waking and sleep states are characterized by considerable changes in neuronal firing. During waking, neurons fire tonically at irregular intervals and a desynchronized activity is observed at the electroencephalogram. This activity becomes synchronized with slow wave sleep onset when neurons start to oscillate between periods of firing (up-states) and periods of silence (down-states). Recently, it has been proposed that the connections between neurons undergo potentiation during waking, whereas they weaken during slow wave sleep. Here, we propose a dynamical model to describe basic features of the autonomous transitions between such states. We consider a network of coupled neurons in which the strength of the interactions is modulated by synaptic long term potentiation and depression, according to the spike time-dependent plasticity rule (STDP). The model shows that the enhancement of synaptic strength between neurons occurring in waking increases the propensity of the network to synchronize and, conversely, desynchronization appears when the strength of the connections become weaker. Both transitions appear spontaneously, but the transition from sleep to waking required a slight modification of the STDP rule with the introduction of a mechanism which becomes active during sleep and changes the proportion between potentiation and depression in accordance with biological data. At the neuron level, transitions from desynchronization to synchronization and vice versa can be described as a bifurcation between two different states, whose dynamical regime is modulated by synaptic strengths, thus suggesting that transition from a state to an another can be determined by quantitative differences between potentiation and depression.
Predicting Noise From Wind Turbines
NASA Technical Reports Server (NTRS)
Grosveld, Ferdinand W.
1990-01-01
Computer program WINDY predicts broadband noise spectra of horizontal-axis wind-turbine generators. Enables adequate assessment of impact of broadband wind-turbine noise. Effects of turbulence, trailing-edge wakes, and bluntness taken into account. Program has practical application in design and siting of wind-turbine machines acceptable to community. Written in GW-Basic.
ERIC Educational Resources Information Center
Collins, Mary Ellen
2011-01-01
Some institutions create a gift fee to pay for a campaign or to cover basic fundraising costs, and especially today, many are doing it in order to increase revenues in the wake of the recession's effect on endowments. In the best circumstances, gift fees are emblematic of a transparent, accountable development process, where donors understand that…
Comment: What Constitutes Evidence in Science Education Research?
ERIC Educational Resources Information Center
Roth, Wolff-Michael
2011-01-01
In the wake of an increasing political commitment to evidence-based decision making and evidence-based educational reform that emerged with the No Child Left Behind effort, the question of what counts as evidence has become increasingly important in the field of science education. In current public discussions, academics, politicians, and other…
Transcendental experiences during meditation practice.
Travis, Frederick
2014-01-01
This article explores transcendental experiences during meditation practice and the integration of transcendental experiences and the unfolding of higher states of consciousness with waking, dreaming, and sleeping. The subject/object relationship during transcendental experiences is characterized by the absence of time, space, and body sense--the framework that gives meaning to waking experiences. Physiologically, transcendental experiences during Transcendental Meditation practice are marked by slow inhalation, along with autonomic orientation at the onset of breath changes and heightened α1 (8-10 Hz) frontal coherence. The integration of transcendental experiences with waking, dreaming, and sleeping is also marked by distinct subjective and objective markers. This integrated state, called Cosmic Consciousness in the Vedic tradition, is subjectively marked by inner self-awareness coexisting with waking, sleeping, and dreaming. Physiologically, Cosmic Consciousness is marked by the coexistence of α1 electroencephalography (EEG) with delta EEG during deep sleep, and higher brain integration, greater emotional stability, and decreased anxiety during challenging tasks. Transcendental experiences may be the engine that fosters higher human development. © 2013 New York Academy of Sciences.
Flow Characteristics of Ground Vehicle Wake and Its Response to Flow Control
NASA Astrophysics Data System (ADS)
Sellappan, Prabu; McNally, Jonathan; Alvi, Farrukh
2017-11-01
Air pollution, fuel shortages, and cost savings are some of the many incentives for improving the aerodynamics of vehicles. Reducing wake-induced aerodynamic drag, which is dependent on flow topology, on modern passenger vehicles is important for improving fuel consumption rates which directly affect the environment. In this research, an active flow control technique is applied on a generic ground vehicle, a 25°Ahmed model, to investigate its effect on the flow topology in the near-wake. The flow field of this canonical bluff body is extremely rich, with complex and unsteady flow features such as trailing wake vortices and c-pillar vortices. The spatio-temporal response of these flow features to the application of steady microjet actuators is investigated. The responses are characterized independently through time-resolved and volumetric velocity field measurements. The accuracy and cost of volumetric measurements in this complex flow field through Stereoscopic- and Tomographic- Particle Image Velocimetry (PIV) will also be commented upon. National Science Foundation PIRE Program.
NASA Astrophysics Data System (ADS)
Wang, Shizhao; He, Guowei; Liu, Tianshu
2017-11-01
The Kutta-Joukowski (KJ) theorem usually leads to puzzling results when it is applied to estimating the lift from the unsteady wakes generated by flapping wings. We investigate this problem by using a prevalent flapping rectangular wing model, where the unsteady wakes are obtained by numerically solving the Navier-Stokes equations at a low Reynolds number. It is found that neither the unsteady nor the time-averaged lift coefficient is correctly predicted when the parameters for the KJ theorem are selected according to the widely accepted ways in the literature. We propose a vorticity-weighted wake width model based on the vortex impulse theory to improve the prediction of the time-averaged lift. Furthermore, we investigate the phase difference of unsteady lift caused by the quasi-steady assumption of the application of the KJ theorem to the flapping flight and quantitatively link the phase difference to the local fluid acceleration. We show the phase difference can be corrected by using an added mass lift model. This work is helpful to clarify the error in estimating the lift of animal flight. Supported by the National Natural Science Foundation of China (No. 11672305).
Wind Farm LES Simulations Using an Overset Methodology
NASA Astrophysics Data System (ADS)
Ananthan, Shreyas; Yellapantula, Shashank
2017-11-01
Accurate simulation of wind farm wakes under realistic atmospheric inflow conditions and complex terrain requires modeling a wide range of length and time scales. The computational domain can span several kilometers while requiring mesh resolutions in O(10-6) to adequately resolve the boundary layer on the blade surface. Overset mesh methodology offers an attractive option to address the disparate range of length scales; it allows embedding body-confirming meshes around turbine geomtries within nested wake capturing meshes of varying resolutions necessary to accurately model the inflow turbulence and the resulting wake structures. Dynamic overset hole-cutting algorithms permit relative mesh motion that allow this nested mesh structure to track unsteady inflow direction changes, turbine control changes (yaw and pitch), and wake propagation. An LES model with overset mesh for localized mesh refinement is used to analyze wind farm wakes and performance and compared with local mesh refinements using non-conformal (hanging node) unstructured meshes. Turbine structures will be modeled using both actuator line approaches and fully-resolved structures to test the efficacy of overset methods for wind farm applications. Exascale Computing Project (ECP), Project Number: 17-SC-20-SC, a collaborative effort of two DOE organizations - the Office of Science and the National Nuclear Security Administration.
On aerodynamic wake analysis and its relation to total aerodynamic drag in a wind tunnel environment
NASA Astrophysics Data System (ADS)
Guterres, Rui M.
The present work was developed with the goal of advancing the state of the art in the application of three-dimensional wake data analysis to the quantification of aerodynamic drag on a body in a low speed wind tunnel environment. Analysis of the existing tools, their strengths and limitations is presented. Improvements to the existing analysis approaches were made. Software tools were developed to integrate the analysis into a practical tool. A comprehensive derivation of the equations needed for drag computations based on three dimensional separated wake data is developed. A set of complete steps ranging from the basic mathematical concept to the applicable engineering equations is presented. An extensive experimental study was conducted. Three representative body types were studied in varying ground effect conditions. A detailed qualitative wake analysis using wake imaging and two and three dimensional flow visualization was performed. Several significant features of the flow were identified and their relation to the total aerodynamic drag established. A comprehensive wake study of this type is shown to be in itself a powerful tool for the analysis of the wake aerodynamics and its relation to body drag. Quantitative wake analysis techniques were developed. Significant post processing and data conditioning tools and precision analysis were developed. The quality of the data is shown to be in direct correlation with the accuracy of the computed aerodynamic drag. Steps are taken to identify the sources of uncertainty. These are quantified when possible and the accuracy of the computed results is seen to significantly improve. When post processing alone does not resolve issues related to precision and accuracy, solutions are proposed. The improved quantitative wake analysis is applied to the wake data obtained. Guidelines are established that will lead to more successful implementation of these tools in future research programs. Close attention is paid to implementation of issues that are of crucial importance for the accuracy of the results and that are not detailed in the literature. The impact of ground effect on the flows in hand is qualitatively and quantitatively studied. Its impact on the accuracy of the computations as well as the wall drag incompatibility with the theoretical model followed are discussed. The newly developed quantitative analysis provides significantly increased accuracy. The aerodynamic drag coefficient is computed within one percent of balance measured value for the best cases.
The New Millennium and an Education That Captures the Basic Spirit of Science.
ERIC Educational Resources Information Center
Bybee, Rodger W.
This document discusses reflections of the old and new millennium on education that capture the basic spirit of science. The explanation includes basic scientific ideas in physical sciences, earth systems, solar system and space; living systems; basic scientific thinking; the basic distinction between science and technology; basic connections…
77 FR 5246 - Basic Energy Sciences Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-02
... DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Office of Science... of the Basic Energy Sciences Advisory Committee (BESAC). The Federal Advisory Committee Act (Pub. L... FURTHER INFORMATION CONTACT: Katie Perine; Office of Basic Energy Sciences; U.S. Department of Energy...
76 FR 48147 - Basic Energy Sciences Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-08
... DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of renewal of the Basic Energy Sciences Advisory Committee. SUMMARY... that the Basic Energy Sciences Advisory Committee will be renewed for a two-year period beginning July...
Direct Numerical Simulations of Transitional/Turbulent Wakes
NASA Technical Reports Server (NTRS)
Rai, Man Mohan
2011-01-01
The interest in transitional/turbulent wakes spans the spectrum from an intellectual pursuit to understand the complex underlying physics to a critical need in aeronautical engineering and other disciplines to predict component/system performance and reliability. Cylinder wakes have been studied extensively over several decades to gain a better understanding of the basic flow phenomena that are encountered in such flows. Experimental, computational and theoretical means have been employed in this effort. While much has been accomplished there are many important issues that need to be resolved. The physics of the very near wake of the cylinder (less than three diameters downstream) is perhaps the most challenging of them all. This region comprises the two detached shear layers, the recirculation region and wake flow. The interaction amongst these three components is to some extent still a matter of conjecture. Experimental techniques have generated a large percentage of the data that have provided us with the current state of understanding of the subject. More recently computational techniques have been used to simulate cylinder wakes, and the data from such simulations are being used to both refine our understanding of such flows as well as provide new insights. A few large eddy and direct numerical simulations (LES and DNS) of cylinder wakes have appeared in the literature in the recent past. These investigations focus on the low Reynolds number range where the cylinder boundary layer is laminar (sub-critical range). However, from an engineering point of view, there is considerable interest in the situation where the upper and/or lower boundary layer of an airfoil is turbulent, and these turbulent boundary layers separate from the airfoil to contribute to the formation of the wake downstream. In the case of cylinders, this only occurs at relatively large unit Reynolds numbers. However, in the case of airfoils, the boundary layer has the opportunity to transition to turbulence on the airfoil surface at a relatively lower unit Reynolds number because the characteristic length of the airfoil is typically one to two orders of magnitude larger than the trailing edge diameter. This transition to turbulence would occur unless there is a strong favorable pressure gradient that results in the boundary layer remaining laminar or transitional over the surface of the airfoil. This presentation will focus on two direct numerical simulations that have been performed at NASA ARC. The first is of a cylinder wake with laminar separating boundary layers. The second is the wake of a flat plate with a circular trailing edge. The upper and lower plate surface boundary layers are both turbulent and statistically identical. Thus the computed wake is symmetric in a statistical sense. This flow is more representative of airfoil wakes than cylinder wakes. Results from the two simulations including flow visualization and turbulence statistics in the near wake will be presented at the seminar.
State-of-the-Art Study for High-speed Deceleration and Stabilization Devices
NASA Technical Reports Server (NTRS)
Alexander, W. C.; Lau, R. A.
1966-01-01
Documented aerodynamic deployable decelerator performance data above Mach 1. 0 is presented. The state of the art of drag and stability characteristics for reentry and recovery applications is defined for a wide range of decelerator configurations. Structural and material data and other design information also are presented. Emphasis is given to presentation of basic aero, thermal, and structural design data, which points out basic problem areas and voids in existing technology. The basic problems and voids include supersonic "buzzing" of towed porous decelerators in the wake of the forebody, the complete lack of dynamic stability data, and the general lack of aerothermal data at speeds above Mach 5.
The Transition from Thick to Thin Plate Wake Physics: Whither Vortex Shedding?
NASA Technical Reports Server (NTRS)
Rai, Man Mohan
2016-01-01
The near and very near wake of a flat plate with a circular trailing edge is investigated with data from direct numerical simulations. Computations were performed for six different combinations of the Reynolds numbers based on plate thickness (D) and boundary layer momentum thickness upstream of the trailing edge (theta). Unlike the case of the cylinder, these Reynolds numbers are independent parameters for the flat plate. The separating boundary layers are turbulent in all the cases investigated. One objective of the study is to understand the changes in the wake vortex shedding process as the plate thickness is reduced (increasing theta/D). The value of D varies by a factor of 16 and that of theta by approximately 5 in the computations. Vortex shedding is vigorous in the low theta/D cases with a substantial decrease in shedding intensity in the large theta/D cases. Other shedding characteristics are also significantly altered with increasing theta/D. A visualization of the shedding process in the different cases is provided and discussed. The basic shedding mechanism is explored in depth. The effect of changing theta/D on the time-averaged, near-wake velocity statistics is also discussed. A functional relationship between the shedding frequency and the Reynolds numbers mentioned above is obtained.
Yamazaki, Yuka; Uka, Takanori; Shimizu, Haruhiko; Miyahira, Akira; Sakai, Tatsuo; Marui, Eiji
2013-02-01
The number of physicians engaged in basic sciences and teaching is sharply decreasing in Japan. To alleviate this shortage, central government has increased the quota of medical students entering the field. This study investigated medical students' interest in basic sciences in efforts to recruit talent. A questionnaire distributed to 501 medical students in years 2 to 6 of Juntendo University School of Medicine inquired about sex, grade, interest in basic sciences, interest in research, career path as a basic science physician, faculties' efforts to encourage students to conduct research, increases in the number of lectures, and practical training sessions on research. Associations between interest in basic sciences and other variables were examined using χ(2) tests. From among the 269 medical students (171 female) who returned the questionnaire (response rate 53.7%), 24.5% of respondents were interested in basic sciences and half of them considered basic sciences as their future career. Obstacles to this career were their original aim to become a clinician and concerns about salary. Medical students who were likely to be interested in basic sciences were fifth- and sixth-year students, were interested in research, considered basic sciences as their future career, considered faculties were making efforts to encourage medical students to conduct research, and wanted more research-related lectures. Improving physicians' salaries in basic sciences is important for securing talent. Moreover, offering continuous opportunities for medical students to experience research and encouraging advanced-year students during and after bedside learning to engage in basic sciences are important for recruiting talent.
Identification of Causal Genes, Networks, and Transcriptional Regulators of REM Sleep and Wake
Millstein, Joshua; Winrow, Christopher J.; Kasarskis, Andrew; Owens, Joseph R.; Zhou, Lili; Summa, Keith C.; Fitzpatrick, Karrie; Zhang, Bin; Vitaterna, Martha H.; Schadt, Eric E.; Renger, John J.; Turek, Fred W.
2011-01-01
Study Objective: Sleep-wake traits are well-known to be under substantial genetic control, but the specific genes and gene networks underlying primary sleep-wake traits have largely eluded identification using conventional approaches, especially in mammals. Thus, the aim of this study was to use systems genetics and statistical approaches to uncover the genetic networks underlying 2 primary sleep traits in the mouse: 24-h duration of REM sleep and wake. Design: Genome-wide RNA expression data from 3 tissues (anterior cortex, hypothalamus, thalamus/midbrain) were used in conjunction with high-density genotyping to identify candidate causal genes and networks mediating the effects of 2 QTL regulating the 24-h duration of REM sleep and one regulating the 24-h duration of wake. Setting: Basic sleep research laboratory. Patients or Participants: Male [C57BL/6J × (BALB/cByJ × C57BL/6J*) F1] N2 mice (n = 283). Interventions: None. Measurements and Results: The genetic variation of a mouse N2 mapping cross was leveraged against sleep-state phenotypic variation as well as quantitative gene expression measurement in key brain regions using integrative genomics approaches to uncover multiple causal sleep-state regulatory genes, including several surprising novel candidates, which interact as components of networks that modulate REM sleep and wake. In particular, it was discovered that a core network module, consisting of 20 genes, involved in the regulation of REM sleep duration is conserved across the cortex, hypothalamus, and thalamus. A novel application of a formal causal inference test was also used to identify those genes directly regulating sleep via control of expression. Conclusion: Systems genetics approaches reveal novel candidate genes, complex networks and specific transcriptional regulators of REM sleep and wake duration in mammals. Citation: Millstein J; Winrow CJ; Kasarskis A; Owens JR; Zhou L; Summa KC; Fitzpatrick K; Zhang B; Vitaterna MH; Schadt EE; Renger JJ; Turek FW. Identification of causal genes, networks, and transcriptional regulators of REM sleep and wake. SLEEP 2011;34(11):1469-1477. PMID:22043117
NASA Astrophysics Data System (ADS)
Mukherjee, Nibedita; Dahdouh-Guebas, Farid; Kapoor, Vena; Arthur, Rohan; Koedam, Nico; Sridhar, Aarthi; Shanker, Kartik
2010-09-01
More than half a decade has passed since the December 26th 2004 tsunami hit the Indian coast leaving a trail of ecological, economic and human destruction in its wake. We reviewed the coastal ecological research carried out in India in the light of the tsunami. In addition, we also briefly reviewed the ecological research in other tsunami affected countries in Asia namely Sri Lanka, Indonesia, Thailand and Maldives in order to provide a broader perspective of ecological research after tsunami. A basic search in ISI Web of Knowledge using keywords “tsunami” and “India” resulted in 127 peer reviewed journal articles, of which 39 articles were pertaining to ecological sciences. In comparison, Sri Lanka, Indonesia, Thailand and Maldives had, respectively, eight, four, 21 and two articles pertaining to ecology. In India, bioshields received the major share of scientific interest (14 out of 39) while only one study (each) was dedicated to corals, seagrasses, seaweeds and meiofauna, pointing to the paucity of research attention dedicated to these critical ecosystems. We noted that very few interdisciplinary studies looked at linkages between pure/applied sciences and the social sciences in India. In addition, there appears to be little correlation between the limited research that was done and its influence on policy in India. This review points to gap areas in ecological research in India and highlights the lessons learnt from research in other tsunami-affected countries. It also provides guidance on the links between science and policy that are required for effective coastal zone management.
NOAA Atmospheric Sciences Modeling Division support to the US Environmental Protection Agency
NASA Astrophysics Data System (ADS)
Poole-Kober, Evelyn M.; Viebrock, Herbert J.
1991-07-01
During FY-1990, the Atmospheric Sciences Modeling Division provided meteorological research and operational support to the U.S. Environmental Protection Agency. Basic meteorological operational support consisted of applying dispersion models and conducting dispersion studies and model evaluations. The primary research effort was the development and evaluation of air quality simulation models using numerical and physical techniques supported by field studies. Modeling emphasis was on the dispersion of photochemical oxidants and particulate matter on urban and regional scales, dispersion in complex terrain, and the transport, transformation, and deposition of acidic materials. Highlights included expansion of the Regional Acid Deposition Model/Engineering Model family to consist of the Tagged Species Engineering Model, the Non-Depleting Model, and the Sulfate Tracking Model; completion of the Acid-MODES field study; completion of the RADM2.1 evaluation; completion of the atmospheric processes section of the National Acid Precipitation Assessment Program 1990 Integrated Assessment; conduct of the first field study to examine the transport and entrainment processes of convective clouds; development of a Regional Oxidant Model-Urban Airshed Model interface program; conduct of an international sodar intercomparison experiment; incorporation of building wake dispersion in numerical models; conduct of wind-tunnel simulations of stack-tip downwash; and initiation of the publication of SCRAM NEWS.
Appraisal of ALM predictions of turbulent wake features
NASA Astrophysics Data System (ADS)
Rocchio, Benedetto; Cilurzo, Lorenzo; Ciri, Umberto; Salvetti, Maria Vittoria; Leonardi, Stefano
2017-11-01
Wind turbine blades create a turbulent wake that may persist far downstream, with significant implications on wind farm design and on its power production. The numerical representation of the real blade geometry would lead to simulations beyond the present computational resources. We focus our attention on the Actuator Line Model (ALM), in which the blade is replaced by a rotating line divided into finite segments with representative aerodynamic coefficients. The total aerodynamic force is projected along the computational axis and, to avoid numerical instabilities, it is distributed among the nearest grid points by using a Gaussian regularization kernel. The standard deviation of this kernel is a fundamental parameter that strongly affects the characteristics of the wake. We compare here the wake features obtained in direct numerical simulations of the flow around 2D bodies (a flat plate and an airfoil) modeled using the Immersed Boundary Method with the results of simulations in which the body is modeled by ALM. In particular, we investigate whether the ALM is able to reproduce the mean velocity field and the turbulent kinetic energy in the wake for the considered bodies at low and high angles of attack and how this depends on the choice of the ALM kernel. S. Leonardi was supported by the National Science Foundation, Grant No. 1243482 (the WINDINSPIRE project).
Yamazaki, Yuka; Uka, Takanori; Shimizu, Haruhiko; Miyahira, Akira; Sakai, Tatsuo; Marui, Eiji
2012-09-01
The number of physicians engaged in basic science and teaching is sharply decreasing in Japan. To alleviate this shortage, central government has increased the quota of medical students entering the field. This study aimed to determine the characteristics of physicians who are engaged in basic science in efforts to recruit talent. A questionnaire was distributed to all 30 physicians in the basic science departments of Juntendo University School of Medicine. Question items inquired about sex, years since graduation, years between graduation and time entering basic science, clinical experience, recommending the career to medical students, expected obstacles to students entering basic science, efforts to inspire students in research, increased number of lectures and practical training sessions on research, and career choice satisfaction. Correlations between the variables were examined using χ(2) tests. Overall, 26 physicians, including 7 female physicians, returned the questionnaire (response rate 86.7%). Most physicians were satisfied with their career choice. Medical students were deemed not to choose basic science as their future career, because they aimed to become clinicians and because they were concerned about salary. Women physicians in basic science departments were younger than men. Women physicians also considered themselves to make more efforts in inspiring medical students to be interested in research. Moreover, physicians who became basic scientists earlier in their career wanted more research-related lectures in medical education. Improving physicians' salaries in basic science is important to securing talent. In addition, basic science may be a good career path for women physicians to follow.
Transformers: Movement Experiences for Early Childhood Classrooms
ERIC Educational Resources Information Center
Vagovic, Julia
2008-01-01
Transformers are simple movement experiences for the classroom that engage the mind and body, focus energy, and help children transition to the next activity. Teachers can use them throughout the day, every day. The author explains the basic movements and suggests ways to build on them. They range from deep breathing to gentle wake-up movements to…
Sleep Disrupts High-Level Speech Parsing Despite Significant Basic Auditory Processing.
Makov, Shiri; Sharon, Omer; Ding, Nai; Ben-Shachar, Michal; Nir, Yuval; Zion Golumbic, Elana
2017-08-09
The extent to which the sleeping brain processes sensory information remains unclear. This is particularly true for continuous and complex stimuli such as speech, in which information is organized into hierarchically embedded structures. Recently, novel metrics for assessing the neural representation of continuous speech have been developed using noninvasive brain recordings that have thus far only been tested during wakefulness. Here we investigated, for the first time, the sleeping brain's capacity to process continuous speech at different hierarchical levels using a newly developed Concurrent Hierarchical Tracking (CHT) approach that allows monitoring the neural representation and processing-depth of continuous speech online. Speech sequences were compiled with syllables, words, phrases, and sentences occurring at fixed time intervals such that different linguistic levels correspond to distinct frequencies. This enabled us to distinguish their neural signatures in brain activity. We compared the neural tracking of intelligible versus unintelligible (scrambled and foreign) speech across states of wakefulness and sleep using high-density EEG in humans. We found that neural tracking of stimulus acoustics was comparable across wakefulness and sleep and similar across all conditions regardless of speech intelligibility. In contrast, neural tracking of higher-order linguistic constructs (words, phrases, and sentences) was only observed for intelligible speech during wakefulness and could not be detected at all during nonrapid eye movement or rapid eye movement sleep. These results suggest that, whereas low-level auditory processing is relatively preserved during sleep, higher-level hierarchical linguistic parsing is severely disrupted, thereby revealing the capacity and limits of language processing during sleep. SIGNIFICANCE STATEMENT Despite the persistence of some sensory processing during sleep, it is unclear whether high-level cognitive processes such as speech parsing are also preserved. We used a novel approach for studying the depth of speech processing across wakefulness and sleep while tracking neuronal activity with EEG. We found that responses to the auditory sound stream remained intact; however, the sleeping brain did not show signs of hierarchical parsing of the continuous stream of syllables into words, phrases, and sentences. The results suggest that sleep imposes a functional barrier between basic sensory processing and high-level cognitive processing. This paradigm also holds promise for studying residual cognitive abilities in a wide array of unresponsive states. Copyright © 2017 the authors 0270-6474/17/377772-10$15.00/0.
Towards enhancing and delaying disturbances in free shear flows
NASA Technical Reports Server (NTRS)
Criminale, W. O.; Jackson, T. L.; Lasseigne, D. G.
1994-01-01
The family of shear flows comprising the jet, wake, and the mixing layer are subjected to perturbations in an inviscid incompressible fluid. By modeling the basic mean flows as parallel with piecewise linear variations for the velocities, complete and general solutions to the linearized equations of motion can be obtained in closed form as functions of all space variables and time when posed as an initial value problem. The results show that there is a continuous as well as the discrete spectrum that is more familiar in stability theory and therefore there can be both algebraic and exponential growth of disturbances in time. These bases make it feasible to consider control of such flows. To this end, the possibility of enhancing the disturbances in the mixing layer and delaying the onset in the jet and wake is investigated. It is found that growth of perturbations can be delayed to a considerable degree for the jet and the wake but, by comparison, cannot be enhanced in the mixing layer. By using moving coordinates, a method for demonstrating the predominant early and long time behavior of disturbances in these flows is given for continuous velocity profiles. It is shown that the early time transients are always algebraic whereas the asymptotic limit is that of an exponential normal mode. Numerical treatment of the new governing equations confirm the conclusions reached by use of the piecewise linear basic models. Although not pursued here, feedback mechanisms designed for control of the flow could be devised using the results of this work.
Miller, Nita Lewis; Tvaryanas, Anthony P; Shattuck, Lawrence G
2012-08-01
This study evaluated the effect of accommodating adolescent sleep-wake patterns by altering the timing of the major sleep period of US Army recruits. The quasi-experimental study compared recruits assigned to one of two training companies: one with a customary sleep regimen (20:30 to 04:30) while the other employed a phase-delayed sleep regimen (23:00 to 07:00), the latter aligning better with biologically driven sleep-wake patterns of adolescents. The study was conducted during Basic Combat Training (BCT) at Fort Leonard Wood, Missouri. TRAINEES: The study included 392 trainees: 209 received the intervention, while 183 composed the Comparison group. Demographic and psychophysiological measures were collected on all trainees. Weekly assessments of subjective fatigue and mood, periodic physical fitness, marksmanship scores, and attrition rates from BCT were studied. Actigraphy was collected on approximately 24% of trainees. Based on actigraphy, trainees on the phase-delayed sleep schedule obtained 31 m more sleep/night than trainees on the customary sleep schedule. The Intervention group reported less total mood disturbance relative to baseline. Improvements in marksmanship correlated positively with average nightly sleep during the preceding week when basic marksmanship skills were taught. No differences were seen in physical fitness or attrition rates. In contrast to the Intervention group, the Comparison group was 2.3 times more likely to experience occupationally significant fatigue and 5.5 times more likely to report poor sleep quality. Accommodating adolescent sleep patterns significantly improves mental health and performance in the training environment.
Basic science conferences in residency training: a national survey.
Cruz, P D; Charley, M R; Bergstresser, P R
1987-02-01
Basic science teaching is an important component of dermatology residency training, and the basic science conference is the major tool utilized by departments of dermatology for its implementation. To characterize the role of basic science conferences in dermatology training, a national survey of chief residents was conducted. Although the survey confirmed that a high value is placed on basic science conferences, a surprising finding was a significant level of dissatisfaction among chief residents, particularly those from university-based programs. Results of the survey have been used to redefine our own objectives in basic science teaching and to propose elements of methodology and curriculum.
High-Order Numerical Simulations of Wind Turbine Wakes
NASA Astrophysics Data System (ADS)
Kleusberg, E.; Mikkelsen, R. F.; Schlatter, P.; Ivanell, S.; Henningson, D. S.
2017-05-01
Previous attempts to describe the structure of wind turbine wakes and their mutual interaction were mostly limited to large-eddy and Reynolds-averaged Navier-Stokes simulations using finite-volume solvers. We employ the higher-order spectral-element code Nek5000 to study the influence of numerical aspects on the prediction of the wind turbine wake structure and the wake interaction between two turbines. The spectral-element method enables an accurate representation of the vortical structures, with lower numerical dissipation than the more commonly used finite-volume codes. The wind-turbine blades are modeled as body forces using the actuator-line method (ACL) in the incompressible Navier-Stokes equations. Both tower and nacelle are represented with appropriate body forces. An inflow boundary condition is used which emulates homogeneous isotropic turbulence of wind-tunnel flows. We validate the implementation with results from experimental campaigns undertaken at the Norwegian University of Science and Technology (NTNU Blind Tests), investigate parametric influences and compare computational aspects with existing numerical simulations. In general the results show good agreement between the experiments and the numerical simulations both for a single-turbine setup as well as a two-turbine setup where the turbines are offset in the spanwise direction. A shift in the wake center caused by the tower wake is detected similar to experiments. The additional velocity deficit caused by the tower agrees well with the experimental data. The wake is captured well by Nek5000 in comparison with experiments both for the single wind turbine and in the two-turbine setup. The blade loading however shows large discrepancies for the high-turbulence, two-turbine case. While the experiments predicted higher thrust for the downstream turbine than for the upstream turbine, the opposite case was observed in Nek5000.
3 CFR 8807 - Proclamation 8807 of May 1, 2012. National Building Safety Month, 2012
Code of Federal Regulations, 2013 CFR
2013-01-01
... and standards, they help save lives and prevent disruption in the wake of disaster. Resilient..., withstand, and recover from disasters. We are drawing upon cutting edge science and technology to establish...
ERIC Educational Resources Information Center
Nielsen, Dorte Guldbrand; Gotzsche, Ole; Sonne, Ole; Eika, Berit
2012-01-01
Two major views on the relationship between basic science knowledge and clinical knowledge stand out; the Two-world view seeing basic science and clinical science as two separate knowledge bases and the encapsulated knowledge view stating that basic science knowledge plays an overt role being encapsulated in the clinical knowledge. However, resent…
Café Científico and Wake up with science. Really fun and interesting outreach activities
NASA Astrophysics Data System (ADS)
Farrona, A. M. M.; Vilar, R.
2016-04-01
;Café Científico; is a series of informal discussions connecting research and society. This outreach activity allows people enjoy while engaging with cutting-edge researchers from University of Cantabria. In Santander, since July 2012, we have a meeting on the last Friday of the month, in the ;Café de las Artes;, a special theatre at the city. At the same time, we carry out the same activity only for children: ;Wake up with Science;. Once in a month, usually the third Thursday of every month, at the University, we invite children to participate in a special ;Café Científico; only for the youngest. With this contribution we want to present a successful outreach activity, with two versions, adapted for participants aged. In any case, these activities always attract many people from Cantabria.
Putilov, Arcady A
2017-01-01
Differences between the so-called larks and owls representing the opposite poles of morningness-eveningness dimension are widely known. However, scientific consensus has not yet been reached on the methodology for ranking and typing people along other dimensions of individual variation in their sleep-wake pattern. This review focused on the history and state-of-the-art of the methodology for self-assessment of individual differences in more than one trait or adaptability of the human sleep-wake cycle. The differences between this and other methodologies for the self-assessment of trait- and state-like variation in the perceived characteristics of daily rhythms were discussed and the critical issues that remained to be addressed in future studies were highlighted. These issues include a) a failure to develop a unidimensional scale for scoring chronotypological differences, b) the inconclusive results of the long-lasting search for objective markers of chronotype, c) a disagreement on both number and content of scales required for multidimensional self-assessment of chronobiological differences, d) a lack of evidence for the reliability and/or external validity of most of the proposed scales and e) an insufficient development of conceptualizations, models and model-based quantitative simulations linking the differences between people in their sleep-wake pattern with the differences in the basic parameters of underlying chronoregulatory processes. It seems that, in the nearest future, the wide implementation of portable actigraphic and somnographic devices might lead to the development of objective methodologies for multidimensional assessment and classification of sleep-wake traits and adaptabilities.
Asymptotic expansions for 2D symmetrical laminar wakes
NASA Astrophysics Data System (ADS)
Belan, Marco; Tordella, Daniela
1999-11-01
An extension of the well known asymptotic representation of the 2D laminar incompressible wake past a symmetrical body is presented. Using the thin free shear layer approximation we determined solutions in terms of infinite asymptotic expansions. These are power series of the streamwise space variable with fractional negative coefficients. The general n-th order term has been analytically established. Through analysis of the behaviour of the same expansions inserted into the Navier-Stokes equations, we verified the self-consistency of the approximation showing that at the third order the correction due to pressure variations identically vanishes while the contribution of the longitudinal diffusion is still two-three order of magnitude smaller than that of the transversal diffusion, depending on Re. When the procedure is applied to the Navier-Stokes equations, we showed that further mathematical difficulties do not arise. Where opportune one may thus easily shift to the complete model. Through a spatial multiscaling approach, a brief account on the stability properties of these expansions as representing the non parallel basic flow of 2D wakes will be given.
ERIC Educational Resources Information Center
McCoy, Leah P., Ed.
2002-01-01
This document presents the of an annual educational research forum held at Wake Forest University (Winston-Salem, North Carolina) on December 11, 2002. A table of contents and 27 research studies of high school teaching are included. Studies include: Effects of the Earth/Environmental Science Requirement on High School Science Enrollment in North…
Streamwise evolution of statistical events and the triple correlation in a model wind turbine array
NASA Astrophysics Data System (ADS)
Viestenz, Kyle; Cal, Raúl Bayoán
2013-11-01
Hot-wire anemometry data, obtained from a wind tunnel experiment containing a 3 × 3 wind turbine array, are used to conditionally average the Reynolds stresses. Nine profiles at the centerline behind the array are analyzed to characterize the turbulent velocity statistics of the wake flow. Quadrant analysis yields statistical events occurring in the wake of the wind farm, where quadrants 2 and 4 produce ejections and sweeps, respectively. A balance between these quadrants is expressed via the ΔSo parameter, which attains a maximum value at the bottom tip and changes sign near the top tip of the rotor. These are then associated to the triple correlation term present in the turbulent kinetic energy equation of the fluctuations. The development of these various quantities is assessed in light of wake remediation, energy transport and possess significance in closure models. National Science Foundation: ECCS-1032647.
75 FR 65363 - Basic Behavioral and Social Science Opportunity Network (OppNet)
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-22
... public meeting to promote and publicize the Basic Behavioral and Social Science Opportunity Network (Opp... . Background: The Basic Behavioral and Social Science Opportunity Network (OppNet) is a trans-NIH initiative to expand the agency's funding of basic behavioral and social sciences research (b-BSSR). OppNet prioritizes...
Integration of basic sciences and clinical sciences in oral radiology education for dental students.
Baghdady, Mariam T; Carnahan, Heather; Lam, Ernest W N; Woods, Nicole N
2013-06-01
Educational research suggests that cognitive processing in diagnostic radiology requires a solid foundation in the basic sciences and knowledge of the radiological changes associated with disease. Although it is generally assumed that dental students must acquire both sets of knowledge, little is known about the most effective way to teach them. Currently, the basic and clinical sciences are taught separately. This study was conducted to compare the diagnostic accuracy of students when taught basic sciences segregated or integrated with clinical features. Predoctoral dental students (n=51) were taught four confusable intrabony abnormalities using basic science descriptions integrated with the radiographic features or taught segregated from the radiographic features. The students were tested with diagnostic images, and memory tests were performed immediately after learning and one week later. On immediate and delayed testing, participants in the integrated basic science group outperformed those from the segregated group. A main effect of learning condition was found to be significant (p<0.05). The results of this study support the critical role of integrating biomedical knowledge in diagnostic radiology and shows that teaching basic sciences integrated with clinical features produces higher diagnostic accuracy in novices than teaching basic sciences segregated from clinical features.
Training of physicians for the twenty-first century: role of the basic sciences.
Grande, Joseph P
2009-09-01
Rapid changes in the healthcare environment and public dissatisfaction with the cost and quality of medical care have prompted a critical analysis of how physicians are trained in the United States. Accrediting agencies have catalyzed a transformation from a process based to a competency-based curriculum, both at the undergraduate and the graduate levels. The objective of this overview is to determine how these changes are likely to alter the role of basic science in medical education. Policy statements related to basic science education from the National Board of Medical Examiners (NBME), the Accreditation Council for Graduate Medical Education (ACGME), American Board of Medical Specialties (ABMS), and the Federation of State Medical Boards (FSMB) were reviewed and assessed for common themes. Three primary roles for the basic sciences in medical education are proposed: (1) basic science to support the development of clinical reasoning skills; (2) basic science to support a critical analysis of medical and surgical interventions ("evidence-based medicine"); and (3) basic and translational science to support analysis of processes to improve healthcare ("science of healthcare delivery"). With these roles in mind, several methods to incorporate basic sciences into the curriculum are suggested.
78 FR 6088 - Basic Energy Sciences Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-29
... DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Office of Science... Energy Sciences Advisory Committee (BESAC). The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat... INFORMATION CONTACT: Katie Perine, Office of Basic Energy Sciences, U.S. Department of Energy; SC-22...
Semiannual Report October 1, 1999 through March 31, 2000
2000-04-01
Mark Carpenter (NASA Langley). Textbook Multigrid Efficiency for the Navier-Stokes Equations Boris Diskin A typical modern Reynolds-Averaged...defined as textbook multigrid efficiency (TME), meaning the solutions to the governing system of equations are attained in a computational work...basic elements of the barriers to be overcome in extending textbook efficiencies to the compressible RANS equations, namely entering flows, far wake
The relevance of basic sciences in undergraduate medical education.
Lynch, C; Grant, T; McLoughlin, P; Last, J
2016-02-01
Evolving and changing undergraduate medical curricula raise concerns that there will no longer be a place for basic sciences. National and international trends show that 5-year programmes with a pre-requisite for school chemistry are growing more prevalent. National reports in Ireland show a decline in the availability of school chemistry and physics. This observational cohort study considers if the basic sciences of physics, chemistry and biology should be a prerequisite to entering medical school, be part of the core medical curriculum or if they have a place in the practice of medicine. Comparisons of means, correlation and linear regression analysis assessed the degree of association between predictors (school and university basic sciences) and outcomes (year and degree GPA) for entrants to a 6-year Irish medical programme between 2006 and 2009 (n = 352). We found no statistically significant difference in medical programme performance between students with/without prior basic science knowledge. The Irish school exit exam and its components were mainly weak predictors of performance (-0.043 ≥ r ≤ 0.396). Success in year one of medicine, which includes a basic science curriculum, was indicative of later success (0.194 ≥ r (2) ≤ 0.534). University basic sciences were found to be more predictive than school sciences in undergraduate medical performance in our institution. The increasing emphasis of basic sciences in medical practice and the declining availability of school sciences should mandate medical schools in Ireland to consider how removing basic sciences from the curriculum might impact on future applicants.
Exploring cognitive integration of basic science and its effect on diagnostic reasoning in novices.
Lisk, Kristina; Agur, Anne M R; Woods, Nicole N
2016-06-01
Integration of basic and clinical science knowledge is increasingly being recognized as important for practice in the health professions. The concept of 'cognitive integration' places emphasis on the value of basic science in providing critical connections to clinical signs and symptoms while accounting for the fact that clinicians may not spontaneously articulate their use of basic science knowledge in clinical reasoning. In this study we used a diagnostic justification test to explore the impact of integrated basic science instruction on novices' diagnostic reasoning process. Participants were allocated to an integrated basic science or clinical science training group. The integrated basic science group was taught the clinical features along with the underlying causal mechanisms of four musculoskeletal pathologies while the clinical science group was taught only the clinical features. Participants completed a diagnostic accuracy test immediately after initial learning, and one week later a diagnostic accuracy and justification test. The results showed that novices who learned the integrated causal mechanisms had superior diagnostic accuracy and better understanding of the relative importance of key clinical features. These findings further our understanding of cognitive integration by providing evidence of the specific changes in clinical reasoning when basic and clinical sciences are integrated during learning.
Basic science right, not basic science lite: medical education at a crossroad.
Fincher, Ruth-Marie E; Wallach, Paul M; Richardson, W Scott
2009-11-01
This perspective is a counterpoint to Dr. Brass' article, Basic biomedical sciences and the future of medical education: implications for internal medicine. The authors review development of the US medical education system as an introduction to a discussion of Dr. Brass' perspectives. The authors agree that sound scientific foundations and skill in critical thinking are important and that effective educational strategies to improve foundational science education should be implemented. Unfortunately, many students do not perceive the relevance of basic science education to clinical practice.The authors cite areas of disagreement. They believe it is unlikely that the importance of basic sciences will be diminished by contemporary directions in medical education and planned modifications of USMLE. Graduates' diminished interest in internal medicine is unlikely from changes in basic science education.Thoughtful changes in education provide the opportunity to improve understanding of fundamental sciences, the process of scientific inquiry, and translation of that knowledge to clinical practice.
NASA Astrophysics Data System (ADS)
Xue, Xiaochun; Yu, Yonggang
2017-04-01
Numerical analyses have been performed to study the influence of fast depressurization on the wake flow field of the base-bleed unit (BBU) with a secondary combustion when the base-bleed projectile is propelled out of the muzzle. Two-dimensional axisymmetric Navier-Stokes equations for a multi-component chemically reactive system is solved by Fortran program to calculate the couplings of the internal flow field and wake flow field with consideration of the combustion of the base-bleed propellant and secondary combustion effect. Based on the comparison with the experiments, the unsteady variation mechanism and secondary combustion characteristic of wake flow field under fast depressurization process is obtained numerically. The results show that in the fast depressurization process, the variation extent of the base pressure of the BBU is larger in first 0.9 ms and then decreases gradually and after 1.5 ms, it remains basically stable. The pressure and temperature of the base-bleed combustion chamber experience the decrease and pickup process. Moreover, after the pressure and temperature decrease to the lowest point, the phenomenon that the external gases are flowing back into the base-bleed combustion chamber appears. Also, with the decrease of the initial pressure, the unsteady process becomes shorter and the temperature gradient in the base-bleed combustion chamber declines under the fast depressurization process, which benefits the combustion of the base-bleed propellant.
An ultra-high-speed cinematographic method for the study of wakes in hypersonic ballistic ranges
NASA Astrophysics Data System (ADS)
Koeneke, Axel; Jaeggy, Bernard Charles; Koerber, Germain
1987-11-01
Optical methods are among the only possibilities to study hypersonic wakes in ballistic ranges. Because of the flow velocities involved the methods employed must permit exposure time well below one microsecond. The ISL has used ultrahigh speed visualization techniques for the study of the transition of hypersonic wakes for quite some time, but the means available up to now did not permit investigation of the time-history of the instabilities in the wake. The use of a laser equipped with an acousto-optical modulator is proposed as a source of ultrashort, highly energetic pulses with high repetition rate to be used to record a certain number of images of the same experiment in order to study the time history of these instabilities. Advantages of the laser as a light source are not only the high energies available together with pulse duration down to 20 nanoseconds, but mostly the free choice of repetition rate independently of exposure time, and the possibility to synchronize the pulses with external events. The laser is a point source and as such can be used in a variety of different optical setups. The coherent nature of the laser light even permits holographic techniques. The reception system capable of recording the images at a sufficient rate is the basic problem in the development and use of the proposed setup.
Amygdala Lesions Reduce Cataplexy in Orexin KO mice
Burgess, C.R.; Oishi, Y.; Mochizuki, T.; Peever, J.H.; Scammell, T.E.
2013-01-01
Narcolepsy is characterized by excessive sleepiness and cataplexy, sudden episodes of muscle weakness during waking that are thought to be an intrusion of REM sleep muscle atonia into wakefulness. One of the most striking aspects of cataplexy is that it is often triggered by strong, generally positive emotions, but little is known about the neural pathways through which positive emotions trigger muscle atonia. We hypothesized that the amygdala is functionally important for cataplexy because the amygdala has a role in processing emotional stimuli and it contains neurons that are active during cataplexy. Using anterograde and retrograde tracing in mice, we found that GABAergic neurons in the central nucleus of the amygdala heavily innervate neurons that maintain waking muscle tone such as those in the ventrolateral periaqueductal grey, lateral pontine tegmentum, locus coeruleus, and dorsal raphe. We then found that bilateral, excitotoxic lesions of the amygdala markedly reduced cataplexy in orexin knockout mice, a model of narcolepsy. These lesions did not alter basic sleep/wake behavior, but substantially reduced the triggering of cataplexy. Lesions also reduced the cataplexy events triggered by conditions associated with high arousal and positive emotions (i.e., wheel running and chocolate). These observations demonstrate that the amygdala is a functionally important part of the circuitry underlying cataplexy and suggest that increased amygdala activity in response to emotional stimuli could directly trigger cataplexy by inhibiting brainstem regions that suppress muscle atonia. PMID:23739970
Amygdala lesions reduce cataplexy in orexin knock-out mice.
Burgess, Christian R; Oishi, Yo; Mochizuki, Takatoshi; Peever, John H; Scammell, Thomas E
2013-06-05
Narcolepsy is characterized by excessive sleepiness and cataplexy, sudden episodes of muscle weakness during waking that are thought to be an intrusion of rapid eye movement sleep muscle atonia into wakefulness. One of the most striking aspects of cataplexy is that it is often triggered by strong, generally positive emotions, but little is known about the neural pathways through which positive emotions trigger muscle atonia. We hypothesized that the amygdala is functionally important for cataplexy because the amygdala has a role in processing emotional stimuli and it contains neurons that are active during cataplexy. Using anterograde and retrograde tracing in mice, we found that GABAergic neurons in the central nucleus of the amygdala heavily innervate neurons that maintain waking muscle tone such as those in the ventrolateral periaqueductal gray, lateral pontine tegmentum, locus ceruleus, and dorsal raphe. We then found that bilateral, excitotoxic lesions of the amygdala markedly reduced cataplexy in orexin knock-out mice, a model of narcolepsy. These lesions did not alter basic sleep-wake behavior but substantially reduced the triggering of cataplexy. Lesions also reduced the cataplexy events triggered by conditions associated with high arousal and positive emotions (i.e., wheel running and chocolate). These observations demonstrate that the amygdala is a functionally important part of the circuitry underlying cataplexy and suggest that increased amygdala activity in response to emotional stimuli could directly trigger cataplexy by inhibiting brainstem regions that suppress muscle atonia.
Basic Science Living Skills for Today's World. Teacher's Edition.
ERIC Educational Resources Information Center
Zellers (Robert W.) Educational Services, Johnstown, PA.
This document is a teacher's edition of a basic skills curriculum in science for adult basic education (ABE) students. The course consists of 25 lessons on basic science concepts, designed to give students a good understanding of the biological and physical sciences. Suggested activities and experiments that the student can do are also included.…
NASA Technical Reports Server (NTRS)
Halekas, J. S.; Angelopoulos, V.; Sibeck, D. G.; Khurana, K. K.; Russell, C. T.; Delory, G. T.; Farrell, W. M.; McFadden, J. P.; Bonnell, J. W.; Larson, D.;
2011-01-01
We present observations from the first passage through the lunar plasma wake by one of two spacecraft comprising ARTEMIS (Acceleration, Reconnection, Turbulence, and Electrodynamics of the Moon's Interaction with the Sun), a new lunar mission that re-tasks two of five probes from the THEMIS magnetospheric mission. On Feb 13, 2010, ARTEMIS probe P1 passed through the wake at 3.5 lunar radii downstream from the Moon, in a region between those explored by Wind and the Lunar Prospector, Kaguya, Chandrayaan, and Chang'E missions. ARTEMIS observed interpenetrating proton, alpha particle, and electron populations refilling the wake along magnetic field lines from both flanks. The characteristics of these distributions match expectations from self-similar models of plasma expansion into vacuum, with an asymmetric character likely driven by a combination of a tilted interplanetary magnetic field and an anisotropic incident solar wind electron population. On this flyby, ARTEMIS provided unprecedented measurements of the interpenetrating beams of both electrons and ions naturally produced by the filtration and acceleration effects of electric fields set up during the refilling process. ARTEMIS also measured electrostatic oscillations closely correlated with counter-streaming electron beams in the wake, as previously hypothesized but never before directly measured. These observations demonstrate the capability of the comprehensively instrumented ARTEMIS spacecraft and the potential for new lunar science from this unique two spacecraft constellation.
NASA Technical Reports Server (NTRS)
Halekas, J. S.; Angelopoulos, V.; Sibeck, D. G.; Khurana, K. K.; Russell, C. T.; Delory, G. T.; Farrell, W. M.; McFadden, J. P.; Bonnell, J. W.; Larson, D.;
2014-01-01
We present observations from the first passage through the lunar plasma wake by one of two spacecraft comprising ARTEMIS (Acceleration, Reconnection, Turbulence, and Electrodynamics of the Moon's Interaction with the Sun), a new lunar mission that re-tasks two of five probes from the THEMIS magnetospheric mission. On Feb 13, 2010, ARTEMIS probe P1 passed through the wake at approximately 3.5 lunar radii downstream from the Moon, in a region between those explored by Wind and the Lunar Prospector, Kaguya, Chandrayaan, and Chang'E missions. ARTEMIS observed interpenetrating proton, alpha particle, and electron populations refilling the wake along magnetic field lines from both flanks. The characteristics of these distributions match expectations from self-similar models of plasma expansion into vacuum, with an asymmetric character likely driven by a combination of a tilted interplanetary magnetic field and an anisotropic incident solar wind electron population. On this flyby, ARTEMIS provided unprecedented measurements of the interpenetrating beams of both electrons and ions naturally produced by the filtration and acceleration effects of electric fields set up during the refilling process. ARTEMIS also measured electrostatic oscillations closely correlated with counter-streaming electron beams in the wake, as previously hypothesized but never before directly measured. These observations demonstrate the capability of the comprehensively instrumented ARTEMIS spacecraft and the potential for new lunar science from this unique two spacecraft constellation.
Spencer, Abby L; Brosenitsch, Teresa; Levine, Arthur S; Kanter, Steven L
2008-07-01
Abraham Flexner persuaded the medical establishment of his time that teaching the sciences, from basic to clinical, should be a critical component of the medical student curriculum, thus giving rise to the "preclinical curriculum." However, students' retention of basic science material after the preclinical years is generally poor. The authors believe that revisiting the basic sciences in the fourth year can enhance understanding of clinical medicine and further students' understanding of how the two fields integrate. With this in mind, a return to the basic sciences during the fourth year of medical school may be highly beneficial. The purpose of this article is to (1) discuss efforts to integrate basic science into the clinical years of medical student education throughout the United States and Canada, and (2) describe the highly developed fourth-year basic science integration program at the University of Pittsburgh School of Medicine. In their critical review of medical school curricula of 126 U.S. and 17 Canadian medical schools, the authors found that only 19% of U.S. medical schools and 24% of Canadian medical schools require basic science courses or experiences during the clinical years, a minor increase compared with 1985. Curricular methods ranged from simple lectures to integrated case studies with hands-on laboratory experience. The authors hope to advance the national discussion about the need to more fully integrate basic science teaching throughout all four years of the medical student curriculum by placing a curricular innovation in the context of similar efforts by other U.S. and Canadian medical schools.
ERIC Educational Resources Information Center
DiLullo, Camille; Morris, Harry J.; Kriebel, Richard M.
2009-01-01
Understanding the relevance of basic science knowledge in the determination of patient assessment, diagnosis, and treatment is critical to good medical practice. One method often used to direct students in the fundamental process of integrating basic science and clinical information is problem-based learning (PBL). The faculty facilitated small…
European Science Notes. Volume 41, Number 10,
1987-10-01
the following topics: laminar/turbulent transition in boundary layers; coherent structures in the modeling of turbulent boundary layers, wakes, and jets...of the labeling of a model protein, human immu- indicator. The amount of oxygen produced noglobulin (hIgG), with acridinium ester, can easily be...has concerned cations, and Computer Science. Research model reduction of large-scale systems in the controls area is conducted in the and state and
ERIC Educational Resources Information Center
Association for Education in Journalism and Mass Communication.
The Science Communication Interest Group section of the proceedings contains the following five papers: "Accounting for the Complexity of Causal Explanations in the Wake of an Environmental Risk" (LeeAnn Kahlor, Sharon Dunwoody and Robert J. Griffin); "Construction of Technology Crisis and Safety: News Media's Framing the Y2K…
Williams, Austin D; Mann, Barry D
2017-02-01
As they enter the clinical years, medical students face large adjustments in the acquisition of medical knowledge. We hypothesized that basic science review related to the topic of journal club papers would increase the educational benefit for third-year medical students. Students were randomized either to participation in a review session about basic science related to the journal club paper, or to no review. After one day, and after three months, students were given a 10-question quiz encompassing the basic science and the clinical implications of the paper. Twenty-six of 50 students were randomized to basic science review. These students scored better on both sections of the quiz one day after journal club, but only on basic science questions after three months. Students who participated in basic science review had better knowledge gain and retention. Educational activities building upon foundational knowledge improves learning on clinical rotations. Copyright © 2016 Elsevier Inc. All rights reserved.
The use of simulation in teaching the basic sciences.
Eason, Martin P
2013-12-01
To assess the current use of simulation in medical education, specifically, the teaching of the basic sciences to accomplish the goal of improved integration. Simulation is increasingly being used by the institutions to teach the basic sciences. Preliminary data suggest that it is an effective tool with increased retention and learner satisfaction. Medical education is undergoing tremendous change. One of the directions of that change is increasing integration of the basic and clinical sciences to improve the efficiency and quality of medical education, and ultimately to improve the patient care. Integration is thought to improve the understanding of basic science conceptual knowledge and to better prepare the learners for clinical practice. Simulation because of its unique effects on learning is currently being successfully used by many institutions as a means to produce that integration through its use in the teaching of the basic sciences. Preliminary data indicate that simulation is an effective tool for basic science education and garners high learner satisfaction.
NASA Astrophysics Data System (ADS)
Martinuzzi, Robert
2016-11-01
Quasi-periodic vortex shedding in the turbulent wake of a thin-flat plate placed normal to a uniform stream at Reynolds number of 6700 is investigated based on Particle Image Velocimetry experiments. The wake structure and vortex formation are characterized using a generalized phase average (GPA), a refinement of the triple decomposition of Reynolds and Hussain (1970) incorporating elements of mean-field theory (Stuart, 1958). The resulting analysis highlights the importance of cycle-to-cycle variations in characterizing vortex formation, wake topology and the residual turbulent Reynolds Stresses. For example, it is shown that during high-amplitude cycles vorticity is strongly concentrated within the well-organized shed vortices, whereas during low-amplitude cycles the shed vortices are highly distorted resulting in significant modulation of the shedding frequency. It is found that high-amplitude cycles contribute more to the coherent Reynolds stress field while the low-amplitude cycles contribute to the residual stress field. It is further shown that traditional phase-averaging techniques lead to an over-estimation of the residual stress field. Natural Sciences and Engineering Research Council of Canada.
The progress test as a diagnostic tool for a new PBL curriculum.
Al Alwan, I; Al-Moamary, M; Al-Attas, N; Al Kushi, A; AlBanyan, E; Zamakhshary, M; Al Kadri, H M F; Tamim, H; Magzoub, M; Hajeer, A; Schmidt, H
2011-12-01
The College of Medicine at King Saud bin Abdulaziz University for Health Sciences (KSAU-HS) is running a PBL-based curriculum. A progress test was used to evaluate components of the basic medical and clinical sciences curriculum. To evaluate the performance of students at different levels of the college of medicine curriculum through USMLE-based test that focused on basic medical and clinical sciences topics. The USMLE-based basic medical and clinical sciences progress test has been conducted since 2007. It covers nine topics, including: anatomy; physiology; histology; epidemiology; biochemistry; behavioral sciences, pathology, pharmacology and immunology/microbiology. Here we analyzed results of three consecutive years of all students in years 1-4. There was a good correlation between progress test results and students' GPA. Progress test results in the clinical topics were better than basic medical sciences. In basic medical sciences, results of pharmacology, biochemistry, behavioral sciences and histology gave lower results than the other disciplines. Results of our progress test proved to be a useful indicator for both basic medical sciences and clinical sciences curriculum. Results are being utilized to help in modifying our curriculum.
75 FR 6369 - Basic Energy Sciences Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-09
... DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office... Energy Sciences Advisory Committee (BESAC). Federal Advisory Committee Act (Pub. L. 92- 463, 86 Stat. 770...: Katie Perine; Office of Basic Energy Sciences; U.S. Department of Energy; Germantown Building...
78 FR 38696 - Basic Energy Sciences Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-27
... DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office... Energy Sciences Advisory Committee (BESAC). The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat... INFORMATION CONTACT: Katie Perine; Office of Basic Energy Sciences; U.S. Department of Energy; Germantown...
76 FR 41234 - Basic Energy Sciences Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-13
... DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee (BESAC). Federal Advisory Committee Act (Pub. L. 92- 463, 86 Stat. 770...
77 FR 41395 - Basic Energy Sciences Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-13
... DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee (BESAC). Federal Advisory Committee Act (Pub. L. 92- 463, 86 Stat. 770...
75 FR 41838 - Basic Energy Sciences Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-19
... DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of Open Meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee (BESAC). The Federal Advisory Committee Act (Pub. L. 92-463, 86 Stat...
76 FR 8358 - Basic Energy Sciences Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-14
... DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee (BESAC). Federal Advisory Committee Act (Pub. L. 92- 463, 86 Stat. 770...
A critical narrative review of transfer of basic science knowledge in health professions education.
Castillo, Jean-Marie; Park, Yoon Soo; Harris, Ilene; Cheung, Jeffrey J H; Sood, Lonika; Clark, Maureen D; Kulasegaram, Kulamakan; Brydges, Ryan; Norman, Geoffrey; Woods, Nicole
2018-06-01
'Transfer' is the application of a previously learned concept to solve a new problem in another context. Transfer is essential for basic science education because, to be valuable, basic science knowledge must be transferred to clinical problem solving. Therefore, better understanding of interventions that enhance the transfer of basic science knowledge to clinical reasoning is essential. This review systematically identifies interventions described in the health professions education (HPE) literature that document the transfer of basic science knowledge to clinical reasoning, and considers teaching and assessment strategies. A systematic search of the literature was conducted. Articles related to basic science teaching at the undergraduate level in HPE were analysed using a 'transfer out'/'transfer in' conceptual framework. 'Transfer out' refers to the application of knowledge developed in one learning situation to the solving of a new problem. 'Transfer in' refers to the use of previously acquired knowledge to learn from new problems or learning situations. Of 9803 articles initially identified, 627 studies were retrieved for full text evaluation; 15 were included in the literature review. A total of 93% explored 'transfer out' to clinical reasoning and 7% (one article) explored 'transfer in'. Measures of 'transfer out' fostered by basic science knowledge included diagnostic accuracy over time and in new clinical cases. Basic science knowledge supported learning - 'transfer in' - of new related content and ultimately the 'transfer out' to diagnostic reasoning. Successful teaching strategies included the making of connections between basic and clinical sciences, the use of commonsense analogies, and the study of multiple clinical problems in multiple contexts. Performance on recall tests did not reflect the transfer of basic science knowledge to clinical reasoning. Transfer of basic science knowledge to clinical reasoning is an essential component of HPE that requires further development for implementation and scholarship. © 2018 John Wiley & Sons Ltd and The Association for the Study of Medical Education.
1980-11-01
u r N. rCOL.16 JA Eld Ps of@c 1394 Approved for publto release . p, - _ , r| .. .... . " iinnmrib ....on un.l i td %"n I - _LCLAILIU SECURITY...34Wake Dispersion in Turbomachines." Transac- tions of the ASME, Journal of Basic Engineering, BBD : 688-690. 87 Wagner, J. H., and Okiishi, T. H. 1977
ERIC Educational Resources Information Center
Bergmann, Barbara R.
In the wake of welfare reform efforts, the government is willing to provide or finance a wide range of services for working parents and help them purchase child care and child health insurance. Taken together, these services represent a significant attack on child poverty. Based on a basic needs' budget for families and the high proportion of a…
Adaptive Meshing of Ship Air-Wake Flowfields
2014-10-21
performs cut- cell operations at geometry boundaries. A second-order spatial finite-volume scheme has been incorporated with explicit first order...The cells intersected by the geometry are handled using the “cut- cell ” approach, which is basically creating arbitrary polyhedral elements with...appropriate surface boundary conditions. Any cells completely outside the computational domain are tagged external and not solved in the flow solution
Horizontal integration of the basic sciences in the chiropractic curriculum.
Ward, Kevin P
2010-01-01
Basic science curricula at most chiropractic colleges consist of courses (eg, general anatomy, physiology, biochemistry, etc) that are taught as stand-alone content domains. The lack of integration between basic science disciplines causes difficulties for students who need to understand how the parts function together as an integrated whole and apply this understanding to solving clinical problems. More horizontally integrated basic science curricula could be achieved by several means: integrated Part I National Board of Chiropractic Examiners questions, a broader education for future professors, an increased emphasis on integration within the current model, linked courses, and an integrated, thematic basic science curriculum. Horizontally integrating basic science curricula would require significant efforts from administrators, curriculum committees, and instructional faculty. Once in place this curriculum would promote more clinically relevant learning, improved learning outcomes, and superior vertical integration.
Horizontal Integration of the Basic Sciences in the Chiropractic Curriculum
Ward, Kevin P.
2010-01-01
Basic science curricula at most chiropractic colleges consist of courses (eg, general anatomy, physiology, biochemistry, etc) that are taught as stand-alone content domains. The lack of integration between basic science disciplines causes difficulties for students who need to understand how the parts function together as an integrated whole and apply this understanding to solving clinical problems. More horizontally integrated basic science curricula could be achieved by several means: integrated Part I National Board of Chiropractic Examiners questions, a broader education for future professors, an increased emphasis on integration within the current model, linked courses, and an integrated, thematic basic science curriculum. Horizontally integrating basic science curricula would require significant efforts from administrators, curriculum committees, and instructional faculty. Once in place this curriculum would promote more clinically relevant learning, improved learning outcomes, and superior vertical integration. PMID:21048882
78 FR 47677 - Basic Energy Sciences Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-06
... DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Office of Science, Department of Energy. ACTION: Notice of renewal. SUMMARY: Pursuant to Section 14(a)(2)(A) of the Federal... hereby given that the Basic Energy Sciences Advisory Committee's (BESAC) charter will be renewed for a...
Alternative Methods by Which Basic Science Pharmacy Faculty Can Relate to Clinical Practice.
ERIC Educational Resources Information Center
Kabat, Hugh F.; And Others
1982-01-01
A panel of pharmacy faculty ranked a broad inventory of basic pharmaceutical science topics in terms of their applicability to clinical pharmacy practice. The panel concluded that basic pharmaceutical sciences are essentially applications of foundation areas in biological, physical, and social sciences. (Author/MLW)
Physician perceptions of the role and value of basic science knowledge in daily clinical practice.
Fischer, Jennifer A; Muller-Weeks, Susan
2012-01-01
The role of basic science education in a clinical setting remains unclear. Research to understand how academic clinicians perceive and use this part of their education can aid curricular development. To assess physician's attitudes toward the value of science knowledge in their clinical practice. Academic physicians from three medical schools completed a questionnaire about the utility of basic science education in core clinical tasks and in practice-based learning and improvement. A total of 109 clinical faculty returned the survey. Overall, 89% of the respondents indicated that basic science education is valuable to their clinical practice. When asked about the utility of basic science information in relation to direct patient care, greater than 50% of the doctors felt they use this when diagnosing and communicating with patients. This rose to greater than 60% when asked about choosing treatment options for their patients. Individuals also responded that basic science knowledge is valuable when developing evidence-based best practices. Specifically, 89% felt that they draw upon this information when training students/residents and 84% use this information when reading journal articles. This study shows that basic science education is perceived by responding academic physicians to be important to their clinical work.
Vortex shedding from obstacles: theoretical frequency prediction
NASA Astrophysics Data System (ADS)
Pier, Benoît
2001-11-01
The existence of self-sustained oscillations in spatially developing systems is closely related to the presence of a locally absolutely unstable region. A recent investigation of a ``synthetic wake'' (a wake with no solid obstacle and no reverse flow region) has proved [Pier and Huerre, J. Fluid Mech. 435, 145 (2001)] that the observed Kármán vortex street is a nonlinear elephant global mode. The same criterion is now shown to hold for real obstacles. Local properties are derived from the unperturbed basic flow computed by enforcing a symmetry condition on the central line. Application of the theoretical criterion then yields the expected Strouhal vortex shedding frequency. The thus predicted frequency is in excellent agreement with direct numerical simulations of the complete flow. The use of the frequency selection mechanism to control the vortex shedding will also be discussed.
NASA Astrophysics Data System (ADS)
Tajima, T.; Nakajima, K.; Mourou, G.
2017-02-01
The fundamental idea of Laser Wakefield Acceleration (LWFA) is reviewed. An ultrafast intense laser pulse drives coherent wakefield with a relativistic amplitude robustly supported by the plasma. While the large amplitude of wakefields involves collective resonant oscillations of the eigenmode of the entire plasma electrons, the wake phase velocity ˜ c and ultrafastness of the laser pulse introduce the wake stability and rigidity. A large number of worldwide experiments show a rapid progress of this concept realization toward both the high-energy accelerator prospect and broad applications. The strong interest in this has been spurring and stimulating novel laser technologies, including the Chirped Pulse Amplification, the Thin Film Compression, the Coherent Amplification Network, and the Relativistic Mirror Compression. These in turn have created a conglomerate of novel science and technology with LWFA to form a new genre of high field science with many parameters of merit in this field increasing exponentially lately. This science has triggered a number of worldwide research centers and initiatives. Associated physics of ion acceleration, X-ray generation, and astrophysical processes of ultrahigh energy cosmic rays are reviewed. Applications such as X-ray free electron laser, cancer therapy, and radioisotope production etc. are considered. A new avenue of LWFA using nanomaterials is also emerging.
ERIC Educational Resources Information Center
Noble, David
2000-01-01
Asserts that in the wake of increasing corporate influence from the outside and corresponding pressure for corporate support from within, universities are allowing academic freedom to be diminished. Discusses how this threat to academic freedom has taken at least three forms: suppression, erosion, and corruption. Describes the historical and…
ERIC Educational Resources Information Center
Goodman, Gail S.
2005-01-01
The scientific study of child witnesses has influenced both developmental science and jurisprudence concerning children. Focusing on the author's own studies, 4 categories of research are briefly reviewed: (a) children's eyewitness memory and suggestibility; (b) memory for traumatic events in childhood; (c) disclosure of child sexual abuse; and…
Base pressure associated with incompressible flow past wedges at high Reynolds numbers
NASA Technical Reports Server (NTRS)
Warpinski, N. R.; Chow, W. L.
1979-01-01
A model is suggested to study the viscid-inviscid interaction associated with steady incompressible flow past wedges of arbitrary angles. It is shown from this analysis that the determination of the nearly constant pressure (base pressure) prevailing within the near wake is really the heart of the problem and this pressure can only be determined from these interactive considerations. The basic free streamline flow field is established through two discrete parameters which should adequately describe the inviscid flow around the body and the wake. The viscous flow processes such as boundary-layer buildup along the wedge surface, jet mixing, recompression, and reattachment which occurs along the region attached to the inviscid flow in the sense of the boundary-layer concept, serve to determine the aforementioned parameters needed for the establishment of the inviscid flow. It is found that the point of reattachment behaves as a saddle point singularity for the system of equations describing the viscous recompression process. Detailed results such as the base pressure, pressure distributions on the wedge surface, and the wake geometry as well as the influence of the characteristic Reynolds number are obtained. Discussion of these results and their comparison with the experimental data are reported.
... 2019 Basic and Clinical Science Course, Section 02: Fundamentals and Principles of Ophthalmology 2018-2019 Basic and ... 2019 Basic and Clinical Science Course, Section 02: Fundamentals and Principles of Ophthalmology Print 2018-2019 Basic ...
Integration of Basic and Clinical Sciences: Faculty Perspectives at a U.S. Dental School.
van der Hoeven, Dharini; van der Hoeven, Ransome; Zhu, Liang; Busaidy, Kamal; Quock, Ryan L
2018-04-01
Although dental education has traditionally been organized into basic sciences education (first and second years) and clinical education (third and fourth years), there has been growing interest in ways to better integrate the two to more effectively educate students and prepare them for practice. Since 2012, The University of Texas School of Dentistry at Houston (UTSD) has made it a priority to improve integration of basic and clinical sciences, with a focus to this point on integrating the basic sciences. The aim of this study was to determine the perspectives of basic and clinical science faculty members regarding basic and clinical sciences integration and the degree of integration currently occurring. In October 2016, all 227 faculty members (15 basic scientists and 212 clinicians) were invited to participate in an online survey. Of the 212 clinicians, 84 completed the clinician educator survey (response rate 40%). All 15 basic scientists completed the basic science educator survey (response rate 100%). The majority of basic and clinical respondents affirmed the value of integration (93.3%, 97.6%, respectively) and reported regular integration in their teaching (80%, 86.9%). There were no significant differences between basic scientists and clinicians on perceived importance (p=0.457) and comfort with integration (p=0.240), but the basic scientists were more likely to integrate (p=0.039) and collaborate (p=0.021) than the clinicians. There were no significant differences between generalist and specialist clinicians on importance (p=0.474) and degree (p=0.972) of integration in teaching and intent to collaborate (p=0.864), but the specialists reported feeling more comfortable presenting basic science information (p=0.033). Protected faculty time for collaborative efforts and a repository of integrated basic science and clinical examples for use in teaching and faculty development were recommended to improve integration. Although questions might be raised about the respondents' definition of "integration," this study provides a baseline assessment of perceptions at a dental school that is placing a priority on integration.
Undergraduate basic science preparation for dental school.
Humphrey, Sue P; Mathews, Robert E; Kaplan, Alan L; Beeman, Cynthia S
2002-11-01
In the Institute of Medicines report Dental Education at the Crossroads, it was suggested that dental schools across the country move toward integrated basic science education for dental and medical students in their curricula. To do so, dental school admission requirements and recommendations must be closely reviewed to ensure that students are adequately prepared for this coursework. The purpose of our study was twofold: 1) to identify student dentists' perceptions of their predental preparation as it relates to course content, and 2) to track student dentists' undergraduate basic science course preparation and relate that to DAT performance, basic science course performance in dental school, and Part I and Part II National Board performance. In the first part of the research, a total of ninety student dentists (forty-five from each class) from the entering classes of 1996 and 1997 were asked to respond to a survey. The survey instrument was distributed to each class of students after each completed the largest basic science class given in their second-year curriculum. The survey investigated the area of undergraduate major, a checklist of courses completed in their undergraduate preparation, the relevance of the undergraduate classes to the block basic science courses, and the strength of requiring or recommending the listed undergraduate courses as a part of admission to dental school. Results of the survey, using frequency analysis, indicate that students felt that the following classes should be required, not recommended, for admission to dental school: Microbiology 70 percent, Biochemistry 54.4 percent, Immunology 57.78 percent, Anatomy 50 percent, Physiology 58.89 percent, and Cell Biology 50 percent. The second part of the research involved anonymously tracking undergraduate basic science preparation of the same students with DAT scores, the grade received in a representative large basic science course, and Part I and Part II National Board performance. Using T-test analysis correlations, results indicate that having completed multiple undergraduate basic science courses (as reported by AADSAS BCP hours) did not significantly (p < .05) enhance student performance in any of these parameters. Based on these results, we conclude that student dentists with undergraduate preparation in science and nonscience majors can successfully negotiate the dental school curriculum, even though the students themselves would increase admission requirements to include more basic science courses than commonly required. Basically, the students' recommendations for required undergraduate basic science courses would replicate the standard basic science coursework found in most dental schools: anatomy, histology, biochemistry, microbiology, physiology, and immunology plus the universal foundation course of biology.
Basic Sciences Fertilizing Clinical Microbiology and Infection Management
2017-01-01
Abstract Basic sciences constitute the most abundant sources of creativity and innovation, as they are based on the passion of knowing. Basic knowledge, in close and fertile contact with medical and public health needs, produces distinct advancements in applied sciences. Basic sciences play the role of stem cells, providing material and semantics to construct differentiated tissues and organisms and enabling specialized functions and applications. However, eventually processes of “practice deconstruction” might reveal basic questions, as in de-differentiation of tissue cells. Basic sciences, microbiology, infectious diseases, and public health constitute an epistemological gradient that should also be an investigational continuum. The coexistence of all these interests and their cross-fertilization should be favored by interdisciplinary, integrative research organizations working simultaneously in the analytical and synthetic dimensions of scientific knowledge. PMID:28859345
Circadian Rhythms, Sleep Deprivation, and Human Performance
Goel, Namni; Basner, Mathias; Rao, Hengyi; Dinges, David F.
2014-01-01
Much of the current science on, and mathematical modeling of, dynamic changes in human performance within and between days is dominated by the two-process model of sleep–wake regulation, which posits a neurobiological drive for sleep that varies homeostatically (increasing as a saturating exponential during wakefulness and decreasing in a like manner during sleep), and a circadian process that neurobiologically modulates both the homeostatic drive for sleep and waking alertness and performance. Endogenous circadian rhythms in neurobehavioral functions, including physiological alertness and cognitive performance, have been demonstrated using special laboratory protocols that reveal the interaction of the biological clock with the sleep homeostatic drive. Individual differences in circadian rhythms and genetic and other components underlying such differences also influence waking neurobehavioral functions. Both acute total sleep deprivation and chronic sleep restriction increase homeostatic sleep drive and degrade waking neurobehavioral functions as reflected in sleepiness, attention, cognitive speed, and memory. Recent evidence indicating a high degree of stability in neurobehavioral responses to sleep loss suggests that these trait-like individual differences are phenotypic and likely involve genetic components, including circadian genes. Recent experiments have revealed both sleep homeostatic and circadian effects on brain metabolism and neural activation. Investigation of the neural and genetic mechanisms underlying the dynamically complex interaction between sleep homeostasis and circadian systems is beginning. A key goal of this work is to identify biomarkers that accurately predict human performance in situations in which the circadian and sleep homeostatic systems are perturbed. PMID:23899598
A simple approximation for larval retention around reefs
NASA Astrophysics Data System (ADS)
Cetina-Heredia, Paulina; Connolly, Sean R.
2011-09-01
Estimating larval retention at individual reefs by local scale three-dimensional flows is a significant problem for understanding, and predicting, larval dispersal. Determining larval dispersal commonly involves the use of computationally demanding and expensively calibrated/validated hydrodynamic models that resolve reef wake eddies. This study models variation in larval retention times for a range of reef shapes and circulation regimes, using a reef-scale three-dimensional hydrodynamic model. It also explores how well larval retention time can be estimated based on the "Island Wake Parameter", a measure of the degree of flow turbulence in the wake of reefs that is a simple function of flow speed, reef dimension, and vertical diffusion. The mean residence times found in the present study (0.48-5.64 days) indicate substantial potential for self-recruitment of species whose larvae are passive, or weak swimmers, for the first several days after release. Results also reveal strong and significant relationships between the Island Wake Parameter and mean residence time, explaining 81-92% of the variability in retention among reefs across a range of unidirectional flow speeds and tidal regimes. These findings suggest that good estimates of larval retention may be obtained from relatively coarse-scale characteristics of the flow, and basic features of reef geomorphology. Such approximations may be a valuable tool for modeling connectivity and meta-population dynamics over large spatial scales, where explicitly characterizing fine-scale flows around reef requires a prohibitive amount of computation and extensive model calibration.
Aeroacoustic and wake measurements on a rotating controlled diffusion blade
NASA Astrophysics Data System (ADS)
Davoudi, Behdad
Aeroacoustic and hot-wire wake measurements have been made for Rotating Controlled Diffusion Blades (RCDBs) configured as a 3 and a 9 blade axial fan. Six cases were identified for the three blade configuration based on its performance curve. Also, six cases corresponding to 6 distinct operating conditions: i) an attached flow, ii) a slightly separated flow, iii) deeply separated flow and three cases in the stall region have been selected for the nine blade configuration. These were examined using a detailed data acquisition program. The detailed results include the wake flow patterns and the associated noise radiation. Turbulence intensities and phase averaged velocity magnitudes have been obtained in the downstream region of the fan to represent the basic flow features for each defined case. A beamforming technique has been utilized to properly measure the radiated sound pressure level (SPL) created by the axial fan. Self-noise signatures of the propagated sound (auto-spectral density), corresponding to the defined cases, have been obtained in the range of 200-8000 Hz. Acoustic data and their links to: i) the physics of the flows, ii) aerodynamic loading and iii) fan rotational speed are presented. A semi-empirical model for trailing edge noise (a portion of the axial fan self-noise) was examined. Wake data (mean velocity and turbulence intensity downstream from the fan blades) were used as experimental inputs to these models. The experimental acoustic data and the semi-empirical results have been compared.
The Reorganization of Basic Science Departments in U.S. Medical Schools, 1980-1999.
ERIC Educational Resources Information Center
Mallon, William T.; Biebuyck, Julien F.; Jones, Robert F.
2003-01-01
Constructed a longitudinal database to examine how basic science departments have been reorganized at U.S. medical schools. Found that there were fewer basic science departments in the traditional disciplines of anatomy, biochemistry, microbiology, pharmacology, and physiology in 1999 than in 1980. But as biomedical science has developed in an…
Yamazaki, Yuka; Uka, Takanori; Marui, Eiji
2017-09-15
In Japan, the field of Basic Sciences encompasses clinical, academic, and translational research, as well as the teaching of medical sciences, with both an MD and PhD typically required. In this study, it was hypothesized that the characteristics of a Basic Sciences career path could offer the professional advancement and personal fulfillment that many female medical doctors would find advantageous. Moreover, encouraging interest in Basic Sciences could help stem shortages that Japan is experiencing in medical fields, as noted in the three principal contributing factors: premature resignation of female clinicians, an imbalance of female physicians engaged in research, and a shortage of medical doctors in the Basic Sciences. This study examines the professional and personal fulfillment expressed by Japanese female medical doctors who hold positions in Basic Sciences. Topics include career advancement, interest in medical research, and greater flexibility for parenting. A cross-sectional questionnaire survey was distributed at all 80 medical schools in Japan, directed to 228 female medical doctors whose academic rank was assistant professor or higher in departments of Basic Sciences in 2012. Chi-square tests and the binary logistic regression model were used to investigate the impact of parenthood on career satisfaction, academic rank, salary, etc. The survey response rate of female physicians in Basic Sciences was 54.0%. Regardless of parental status, one in three respondents cited research interest as their rationale for entering Basic Sciences, well over twice other motivations. A majority had clinical experience, with clinical duties maintained part-time by about half of respondents and particularly parents. Only one third expressed afterthoughts about relinquishing full-time clinical practice, with physicians who were parents expressing stronger regrets. Parental status had little effect on academic rank and income within the Basic Sciences, CONCLUSION: Scientific curiosity and a desire to improve community health are hallmarks of those choosing a challenging career in medicine. Therefore, it is unsurprising that interest in research is the primary motivation for a female medical doctor to choose a career in Basic Sciences. Additionally, as with many young professionals with families, female doctors seek balance in professional and private lives. Although many expressed afterthoughts relinquishing a full-time clinical practice, mothers generally benefited from greater job flexibility, with little significant effect on career development and income as Basic Scientists.
Analysis of the basic science section of the orthopaedic in-training examination.
Sheibani-Rad, Shahin; Arnoczky, Steven Paul; Walter, Norman E
2012-08-01
Since 1963, the Orthopaedic In-Training Examination (OITE) has been administered to orthopedic residents to assess residents' knowledge and measure the quality of teaching within individual programs. The OITE currently consists of 275 questions divided among 12 domains. This study analyzed all OITE basic science questions between 2006 and 2010. The following data were recorded: number of questions, question taxonomy, category of question, type of imaging modality, and recommended journal and book references. Between 2006 and 2010, the basic science section constituted 12.2% of the OITE. The assessment of taxonomy classification showed that recall-type questions were the most common, at 81.4%. Imaging modalities typically involved questions on radiographs and constituted 6.2% of the OITE basic science section. The majority of questions were basic science questions (eg, genetics, cell replication, and bone metabolism), with an average of 26.4 questions per year. The Journal of Bone & Joint Surgery (American Volume) and the American Academy of Orthopaedic Surgeons' Orthopaedic Basic Science were the most commonly and consistently cited journal and review book, respectively. This study provides the first review of the question content and recommended references of the OITE basic science section. This information will provide orthopedic trainees, orthopedic residency programs, and the American Academy of Orthopaedic Surgeons Evaluation Committee valuable information related to improving residents' knowledge and performance and optimizing basic science educational curricula. Copyright 2012, SLACK Incorporated.
John, T A
2011-06-01
Basic science departments in academic medical centres are influenced by changes that are commonly directed at medical education and financial gain. Some of such changes may have been detrimental to or may have enhanced basic science education. They may have determined basic science research focus or basic science research methods. However, there is lack of research on the educational process in the basic sciences including training of PhD's while there is ample research on medical education pertaining to training of medical doctors. The author here identifies, from university websites and available literature, some forces that have driven teaching and research focus and methods in state-of-the-arts academic medical centres in recent times with a view of seeing through their possible influences on basic science education and research, using the United States of America as an example. The "forces" are: Changes in medical schools; Medical educational philosophies: problem based learning, evidence based medicine, cyberlearning and self-directed learning; Shifting impressions of the value of basic sciences in medical schools; Research trends in Basic Sciences: role of antivivisectionists, alternative experimentations, explosion of molecular and cell biology; Technological advancements; Commercialization of research; and Funding agencies. The author encourages African leaders in academia to pay attention to such forces as the leadership seeks to raise African Universities as centres of knowledge that have a major role in acquiring, preserving, imparting, and utilizing knowledge.
Back up healthcare marketing with infection-control basics.
Tison-Rossman, J
1993-02-01
In the wake of OSHA's bloodborne pathogens regulation requiring employer-provided apparel for healthcare employees, numerous companies are rushing to capture the market, while others are stepping back for fear that the market is too difficult to serve. Both groups need to reassess their positions. These guidelines adapted from TRSA publications should help get you and your employees up to speed on what it takes to serve the healthcare market.
Connecting Science and Society: Basic Research in the Service of Social Objectives
NASA Astrophysics Data System (ADS)
Sonnert, Gerhard
2007-03-01
A flawed dichotomy of basic versus applied science (or of ``curiosity-driven'' vs. ``mission-oriented'' science) pervades today's thinking about science policy. This talk argues for the addition of a third mode of scientific research, called Jeffersonian science. Whereas basic science, as traditionally understood, is a quest for the unknown regardless of societal needs, and applied science is known science applied to known needs, Jeffersonian science is the quest for the unknown in the service of a known social need. It is research in an identified area of basic scientific ignorance that lies at the heart of a social problem. The talk discusses the conceptual foundations and then provides some case examples of Jeffersonian-type science initiatives, such as the Lewis and Clark Expedition, initiated by Thomas Jefferson (which led us to call this mode of research Jeffersonian), research conducted under the auspices of the National Institutes of Health, and a science policy project by President Jimmy Carter and his Science Adviser, Frank Press, in the late 1970s. Because the concept of Jeffersonian science explicitly ties basic research to the social good, one of the potential benefits of adding a Jeffersonian dimension to our thinking about science is that it might make science careers more attractive to women and underrepresented minorities.
Contributions of Basic Sciences to Science of Education. Studies in Educational Administration.
ERIC Educational Resources Information Center
Lall, Bernard M.
The science of education has been influenced by the basic sciences to the extent that educational research now has been able to modernize its approach by accepting and using the basic scientific methodology and experimental techniques. Using primarily the same steps of scientific investigations, education today holds a place of much greater esteem…
The Effect of Home Related Science Activities on Students' Performance in Basic Science
ERIC Educational Resources Information Center
Obomanu, B. J.; Akporehwe, J. N.
2012-01-01
Our study investigated the effect of utilizing home related science activities on student's performance in some basic science concepts. The concepts considered were heart energy, ecology and mixtures. The sample consisted of two hundred and forty (240) basic junior secondary two (BJSS11) students drawn from a population of five thousand and…
Surface obstacles in pulsatile flow
NASA Astrophysics Data System (ADS)
Carr, Ian A.; Plesniak, Michael W.
2016-11-01
Flows past obstacles mounted on flat surfaces have been widely studied due to their ubiquity in nature and engineering. For nearly all of these studies, the freestream flow over the obstacle was steady, i.e. constant velocity unidirectional flow. Unsteady, pulsatile flows occur frequently in biology, geophysics, biomedical engineering, etc. Our study is aimed at extending the comprehensive knowledge base that exists for steady flows to considerably more complex pulsatile flows. Beyond the important practical applications, characterizing the vortex and wake dynamics of flows around surface obstacles embedded in pulsatile flows can provide insights into the underlying physics in all wake and junction flows. In this study, we experimentally investigated the wake of four canonical surface obstacles: hemisphere, cube, and circular cylinders with aspect ratio of 1:1 and 2:1. Phase-averaged PIV and hot-wire anemometry are used to characterize the dynamics of coherent structures in the wake and at the windward junction of the obstacles. Complex physics occur during the deceleration phase of the pulsatile inflow. We propose a framework for understanding these physics based on self-induced vortex propagation, similar to the phenomena exhibited by vortex rings. This material is based in part upon work supported by the National Science Foundation under Grant Number CBET-1236351, and GW Centeor Biomimetics and Bioinspired Engineering (COBRE).
Control strategies for wind farm power optimization: LES study
NASA Astrophysics Data System (ADS)
Ciri, Umberto; Rotea, Mario; Leonardi, Stefano
2017-11-01
Turbines in wind farms operate in off-design conditions as wake interactions occur for particular wind directions. Advanced wind farm control strategies aim at coordinating and adjusting turbine operations to mitigate power losses in such conditions. Coordination is achieved by controlling on upstream turbines either the wake intensity, through the blade pitch angle or the generator torque, or the wake direction, through yaw misalignment. Downstream turbines can be adapted to work in waked conditions and limit power losses, using the blade pitch angle or the generator torque. As wind conditions in wind farm operations may change significantly, it is difficult to determine and parameterize the variations of the coordinated optimal settings. An alternative is model-free control and optimization of wind farms, which does not require any parameterization and can track the optimal settings as conditions vary. In this work, we employ a model-free optimization algorithm, extremum-seeking control, to find the optimal set-points of generator torque, blade pitch and yaw angle for a three-turbine configuration. Large-Eddy Simulations are used to provide a virtual environment to evaluate the performance of the control strategies under realistic, unsteady incoming wind. This work was supported by the National Science Foundation, Grants No. 1243482 (the WINDINSPIRE project) and IIP 1362033 (I/UCRC WindSTAR). TACC is acknowledged for providing computational time.
[Actigraphy in Bipolar Disorder and First Degree Relatives].
Andrade Carrillo, Rommel; Gómez Cano, Sujey; Palacio Ortiz, Juan David; García Valencia, Jenny
2015-01-01
Bipolar disorder is a disabling disease that involves a significant economic costs to the health system, making it is essential to investigate possible early predictors such as changes in sleep-wake cycle in high-risk populations. To review the available literature on alterations in the sleep-wake cycle and circadian rhythm in patients with bipolar disorder and their first degree relatives. A literature search was performed in the data bases, Access Medicine, ClinicalKey, EMBASE, JAMA, Lilacs, OVID, Oxford Journals, ScienceDirect, SciELO, APA y PsycNET. Articles in both English and Spanish were reviewed, without limits by study type. Actigraphy is a non-invasive, useful method for assessing sleep-wake cycle disturbances in the active phases of bipolar disorder, and during euthymia periods. Actigraphy showed good sensitivity to predict true sleep, but low specificity, compared with polysomnography. Although studies in bipolar offspring and relatives are scarce, they show sleep changes similar to bipolar patients. Actigraphy may be a good screening tool of sleep/wake cycle in patients with bipolar disorders, because it is economic, non-invasive and sensitive. Longitudinal studies are required to evaluate its potential use as a risk marker. Copyright © 2014 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.
Tomo-PIV measurements of the flow field in the wake of a sphere
NASA Astrophysics Data System (ADS)
Eshbal, Lior; David, Tom; Rinsky, Vladislav; van Hout, Rene; Greenblatt, David
2017-11-01
A sphere can be considered as a prototypical 3D bluff body. In order to improve our understanding of its 3D wake flow, a combination of time-resolved planar particle image velocimetry (PIV) and tomographic PIV (tomo-PIV) was implemented. Experiments were performed in a closed-loop water channel facility and sphere Reynolds numbers ReD = UD/ ν = 400, 800, 1200 and 2000, where U is the free-stream velocity, ν the kinematic viscosity and D the sphere diameter. The measurement volume (Height x Length x Width, 5 x 5 x 1.5 D3) comprised the sphere and the downstream wake. Tomo-PIV snap-shots were correlated with the time-resolved PIV such that the 3D temporal evolution of the shed vortices became clear. At ReD = 400, this procedure revealed shed hairpin vortices having a vertical plane of symmetry in agreement with many dye visualization studies. However, the measurements also revealed weaker induced hairpins resulting from the interaction of the near-wake flow and the surrounding free stream. These induced vortices were not visible in previous dye and smoke visualizations and have only been observed in simulations. Data processing of the data at higher ReD is currently ongoing. Israel Science Foundation Grant No. 1596/14.
Stevenson, Frazier T; Bowe, Connie M; Gandour-Edwards, Regina; Kumari, Vijaya G
2005-02-01
Many studies have evaluated the desirability of expert versus non-expert facilitators in problem-based learning (PBL), but performance differences between basic science and clinical facilitators has been less studied. In a PBL course at our university, pairs of faculty facilitators (1 clinician, 1 basic scientist) were assigned to student groups to maximise integration of basic science with clinical science. This study set out to establish whether students evaluate basic science and clinical faculty members differently when they teach side by side. Online questionnaires were used to survey 188 students about their faculty facilitators immediately after they completed each of 3 serial PBL cases. Overall satisfaction was measured using a scale of 1-7 and yes/no responses were gathered from closed questions describing faculty performance. results: Year 1 students rated basic science and clinical facilitators the same, but Year 2 students rated the clinicians higher overall. Year 1 students rated basic scientists higher in their ability to understand the limits of their own knowledge. Year 2 students rated the clinicians higher in several content expertise-linked areas: preparedness, promotion of in-depth understanding, and ability to focus the group, and down-rated the basic scientists for demonstrating overspecialised knowledge. Students' overall ratings of individual faculty best correlated with the qualities of stimulation, focus and preparedness, but not with overspecialisation, excessive interjection of the faculty member's own opinions, and encouragement of psychosocial issue discussion. When taught by paired basic science and clinical PBL facilitators, students in Year 1 rated basic science and clinical PBL faculty equally, while Year 2 students rated clinicians more highly overall. The Year 2 difference may be explained by perceived differences in content expertise.
Do Racial and Gender Disparities Exist in Newer Glaucoma Treatments?
... 2019 Basic and Clinical Science Course, Section 02: Fundamentals and Principles of Ophthalmology 2018-2019 Basic and ... 2019 Basic and Clinical Science Course, Section 02: Fundamentals and Principles of Ophthalmology Print 2018-2019 Basic ...
Steinberg, Benjamin E; Goldenberg, Neil M; Fairn, Gregory D; Kuebler, Wolfgang M; Slutsky, Arthur S; Lee, Warren L
2016-02-01
Explosive growth in our understanding of genomics and molecular biology have fueled calls for the pursuit of personalized medicine, the notion of harnessing biologic variability to provide patient-specific care. This vision will necessitate a deep understanding of the underlying pathophysiology in each patient. Medical journals play a pivotal role in the education of trainees and clinicians, yet we suspected that the amount of basic science in the top medical journals has been in decline. We conducted an automated search strategy in PubMed to identify basic science articles and calculated the proportion of articles dealing with basic science in the highest impact journals for 8 different medical specialties from 1994 to 2013. We observed a steep decline (40-60%) in such articles over time in almost all of the journals examined. This rapid decline in basic science from medical journals is likely to affect practitioners' understanding of and interest in the basic mechanisms of disease and therapy. In this Life Sciences Forum, we discuss why this decline may be occurring and what it means for the future of science and medicine. © FASEB.
Progress in the Utilization of High-Fidelity Simulation in Basic Science Education
ERIC Educational Resources Information Center
Helyer, Richard; Dickens, Peter
2016-01-01
High-fidelity patient simulators are mainly used to teach clinical skills and remain underutilized in teaching basic sciences. This article summarizes our current views on the use of simulation in basic science education and identifies pitfalls and opportunities for progress.
Editorial Commentary: A Model for Shoulder Rotator Cuff Repair and for Basic Science Investigations.
Brand, Jefferson C
2018-04-01
"Breaking the fourth wall" is a theater convention where the narrator or character speaks directly to the audience. As an Assistant Editor-in-Chief, as I comment on a recent basic science study investigating rotator cuff repair, I break the fourth wall and articulate areas of basic science research excellence that align with the vision that we hold for our journal. Inclusion of a powerful video strengthens the submission. We prefer to publish clinical videos in our companion journal, Arthroscopy Techniques, and encourage basic science video submissions to Arthroscopy. Basic science research requires step-by-tedious-step analogous to climbing a mountain. Establishment of a murine rotator cuff repair model was rigorous and research intensive, biomechanically, radiographically, histologically, and genetically documented, a huge step toward the bone-to-tendon healing research summit. This research results in a model for both rotator cuff repair and the pinnacle of quality, basic science research. Copyright © 2018 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.
NASA Technical Reports Server (NTRS)
Morris, Philip J.; McLaughlin, Dennis K.; Gabrielson, Thomas B.; Boluriaan, Said
2004-01-01
This report describes the activities completed under a grant from the NASA Langley Research Center to develop a plan for the assessment, improvement, and deployment of a Radar Acoustic Sounding System (RASS) for the detection of wake vortices. A brief review is provided of existing alternative instruments for wake vortex detection. This is followed by a review of previous implementations and assessment of a RASS. As a result of this review, it is concluded that the basic features of a RASS have several advantages over other commonly used wake vortex detection and measurement systems. Most important of these features are the good fidelity of the measurements and the potential for all weather operation. To realize the full potential of this remote sensing instrument, a plan for the development of a RASS designed specifically for wake vortex detection and measurement has been prepared. To keep costs to a minimum, this program would start with the development an inexpensive laboratory-scale version of a RASS system. The new instrument would be developed in several stages, each allowing for a critical assessment of the instrument s potential and limitations. The instrument, in its initial stages of development, would be tested in a controlled laboratory environment. A jet vortex simulator, a prototype version of which has already been fabricated, would be interrogated by the RASS system. The details of the laboratory vortex would be measured using a Particle Image Velocimetry (PIV) system. In the early development stages, the scattered radar signal would be digitized and the signal post-processed to determine how extensively and accurately the RASS could measure properties of the wake vortex. If the initial tests prove to be successful, a real-time, digital signal processing system would be developed as a component of the RASS system. At each stage of the instrument development and testing, the implications of the scaling required for a full-scale instrument would be considered. It is concluded that a RASS system, developed for the specific application of wake vortex detection, could become part of a robust Aircraft Vortex Spacing System (AVOSS). This system, in turn, could contribute to Reduced Spacing Operations (RSO) in US airports and improvements in Terminal Area productivity (TAP).
Cause and Effect: Testing a Mechanism and Method for the Cognitive Integration of Basic Science.
Kulasegaram, Kulamakan; Manzone, Julian C; Ku, Cheryl; Skye, Aimee; Wadey, Veronica; Woods, Nicole N
2015-11-01
Methods of integrating basic science with clinical knowledge are still debated in medical training. One possibility is increasing the spatial and temporal proximity of clinical content to basic science. An alternative model argues that teaching must purposefully expose relationships between the domains. The authors compared different methods of integrating basic science: causal explanations linking basic science to clinical features, presenting both domains separately but in proximity, and simply presenting clinical features First-year undergraduate health professions students were randomized to four conditions: (1) science-causal explanations (SC), (2) basic science before clinical concepts (BC), (3) clinical concepts before basic science (CB), and (4) clinical features list only (FL). Based on assigned conditions, participants were given explanations for four disorders in neurology or rheumatology followed by a memory quiz and diagnostic test consisting of 12 cases which were repeated after one week. Ninety-four participants completed the study. No difference was found on memory test performance, but on the diagnostic test, a condition by time interaction was found (F[3,88] = 3.05, P < .03, ηp = 0.10). Although all groups had similar immediate performance, the SC group had a minimal decrease in performance on delayed testing; the CB and FL groups had the greatest decreases. These results suggest that creating proximity between basic science and clinical concepts may not guarantee cognitive integration. Although cause-and-effect explanations may not be possible for all domains, making explicit and specific connections between domains will likely facilitate the benefits of integration for learners.
ERIC Educational Resources Information Center
Bloech, Henning
2006-01-01
Five days a week, more than 55 million children, teachers and employees spend the majority of their waking hours in the U.S. school buildings. Besides being exposed to science, history and math, children and teachers are exposed to hundreds if not thousands of potentially hazardous chemicals and pollutants. Because children spend so much time in…
ERIC Educational Resources Information Center
Low, Sam
2003-01-01
To understand and revive the ancient Hawaiian culture, the crew of a traditional Polynesian double-hulled voyaging canoe sails among the Pacific Islands without charts or instruments. Trained by Western science, elders, and experience, the navigator guides the craft by the stars and dead reckoning. Each voyage is linked to Hawaiian classroom…
Basic energy sciences: Summary of accomplishments
NASA Astrophysics Data System (ADS)
1990-05-01
For more than four decades, the Department of Energy, including its predecessor agencies, has supported a program of basic research in nuclear- and energy related sciences, known as Basic Energy Sciences. The purpose of the program is to explore fundamental phenomena, create scientific knowledge, and provide unique user facilities necessary for conducting basic research. Its technical interests span the range of scientific disciplines: physical and biological sciences, geological sciences, engineering, mathematics, and computer sciences. Its products and facilities are essential to technology development in many of the more applied areas of the Department's energy, science, and national defense missions. The accomplishments of Basic Energy Sciences research are numerous and significant. Not only have they contributed to Departmental missions, but have aided significantly the development of technologies which now serve modern society daily in business, industry, science, and medicine. In a series of stories, this report highlights 22 accomplishments, selected because of their particularly noteworthy contributions to modern society. A full accounting of all the accomplishments would be voluminous. Detailed documentation of the research results can be found in many thousands of articles published in peer-reviewed technical literature.
Basic Energy Sciences: Summary of Accomplishments
DOE R&D Accomplishments Database
1990-05-01
For more than four decades, the Department of Energy, including its predecessor agencies, has supported a program of basic research in nuclear- and energy-related sciences, known as Basic Energy Sciences. The purpose of the program is to explore fundamental phenomena, create scientific knowledge, and provide unique user'' facilities necessary for conducting basic research. Its technical interests span the range of scientific disciplines: physical and biological sciences, geological sciences, engineering, mathematics, and computer sciences. Its products and facilities are essential to technology development in many of the more applied areas of the Department's energy, science, and national defense missions. The accomplishments of Basic Energy Sciences research are numerous and significant. Not only have they contributed to Departmental missions, but have aided significantly the development of technologies which now serve modern society daily in business, industry, science, and medicine. In a series of stories, this report highlights 22 accomplishments, selected because of their particularly noteworthy contributions to modern society. A full accounting of all the accomplishments would be voluminous. Detailed documentation of the research results can be found in many thousands of articles published in peer-reviewed technical literature.
NASA Technical Reports Server (NTRS)
Jordan, F. L., Jr.
1980-01-01
As part of basic research to improve aerial applications technology, methods were developed at the Langley Vortex Research Facility to simulate and measure deposition patterns of aerially-applied sprays and granular materials by means of tests with small-scale models of agricultural aircraft and dynamically-scaled test particles. Interactions between the aircraft wake and the dispersed particles are being studied with the objective of modifying wake characteristics and dispersal techniques to increase swath width, improve deposition pattern uniformity, and minimize drift. The particle scaling analysis, test methods for particle dispersal from the model aircraft, visualization of particle trajectories, and measurement and computer analysis of test deposition patterns are described. An experimental validation of the scaling analysis and test results that indicate improved control of chemical drift by use of winglets are presented to demonstrate test methods.
NASA Astrophysics Data System (ADS)
Kozaka, Orçun E.; Özkan, Gökhan; Özdemir, Bedii I.
2004-01-01
Turbulent structure of flow behind a model car is investigated with local velocity measurements with emphasis on large structures and their relevance to aerodynamic forces. Results show that two counter-rotating helical vortices, which are formed within the inner wake region, play a key role in determining the flux of kinetic energy. The turbulence is generated within the outermost shear layers due to the instabilities, which also seem to be the basic drive for these relatively organized structures. The measured terms of the turbulent kinetic energy production, which are only part of the full expression, indicate that vortex centres act similar to the manifolds draining the energy in the streamwise direction. As the approach velocity increases, the streamwise convection becomes the dominant means of turbulent transport and, thus, the acquisition of turbulence by relatively non-turbulent flow around the wake region is suppressed.
NASA Technical Reports Server (NTRS)
Couch, L. M.
1975-01-01
An investigation was conducted at Mach 1.80 in the Langley 4-foot supersonic pressure tunnel to determine the effects of variation in reefing ratio and geometric porosity on the drag and stability characteristics of four basic canopy types deployed in the wake of a cone-cylinder forebody. The basic designs included cross, hemisflo, disk-gap-band, and extended-skirt canopies; however, modular cross and standard flat canopies and a ballute were also investigated. An empirical correlation was determined which provides a fair estimation of the drag coefficients in transonic and supersonic flow for parachutes of specified geometric porosity and reefing ratio.
Basic Sciences Fertilizing Clinical Microbiology and Infection Management.
Baquero, Fernando
2017-08-15
Basic sciences constitute the most abundant sources of creativity and innovation, as they are based on the passion of knowing. Basic knowledge, in close and fertile contact with medical and public health needs, produces distinct advancements in applied sciences. Basic sciences play the role of stem cells, providing material and semantics to construct differentiated tissues and organisms and enabling specialized functions and applications. However, eventually processes of "practice deconstruction" might reveal basic questions, as in de-differentiation of tissue cells. Basic sciences, microbiology, infectious diseases, and public health constitute an epistemological gradient that should also be an investigational continuum. The coexistence of all these interests and their cross-fertilization should be favored by interdisciplinary, integrative research organizations working simultaneously in the analytical and synthetic dimensions of scientific knowledge. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.
ERIC Educational Resources Information Center
Fassett, William E.; Campbell, William H.
1984-01-01
A comparison of Basic Pharmaceutical Sciences Examination (BPSE) results with student performance evaluations in core clerkships, institutional and community externships, didactic and clinical courses, and related basic science coursework revealed the BPSE does not predict student performance during clinical instruction. (MSE)
NASA Astrophysics Data System (ADS)
Rajewski, D. A.
2015-12-01
Wind farms are an important resource for electrical generation in the Central U.S., however with each installation there are many poorly documented interactions with the local and surrounding environment. The impact of wind farms on surface microclimate is largely understood conceptually using numerical or wind tunnel models or ex situ satellite-detected changes. Measurements suitable for calibration of numerical simulations are few and of limited applicability but are urgently needed to improve parameterization of wind farm aerodynamics influenced by the diurnal evolution of the boundary layer. Among large eddy simulations of wind farm wakes in thermally stable stratification, there are discrepancies on the influence of turbine-induced mixing on the surface heat flux. We provide measurements from seven surface flux stations, vertical profiling LiDARs located upwind and downwind of turbines, and SCADA measurements from turbines during the 2013 Crop Wind Energy Experiment (CWEX-13) as the best evidence for the variability of turbine induced heat flux within a large wind farm. Examination of ambient conditions (wind direction, wind veer, and thermal stratification) and on turbine operation factors (hub-height wind speed, normalized power) reveal conditions that lead to the largest modification of heat flux. Our results demonstrate the highest flux change from the reference station to be where the leading few lines of turbines influence the surface. Under stably stratified conditions turbine-scale turbulence is highly efficient at bringing warmer air aloft to the surface, leading to an increase in downward heat flux. Conversely we see that the combination of wakes from several lines of turbines reduces the flux contrast from the reference station. In this regime of deep wind-farm flow, wake turbulence is similar in scale and intensity to the reference conditions. These analysis tools can be extended to other turbine SCADA and microclimate variables (e.g. temperature) to improve basic understanding of turbine-turbine and total wind farm wake interactions. Forthcoming tall-tower measurements will provide additional opportunities for comparison of simulated wind and thermal profiles in non-wake, and waked flow conditions.
The Museum of Science and Industry Basic List of Children's Science Books, 1986.
ERIC Educational Resources Information Center
Richter, Bernice, Comp.; Wenzel, Duane, Comp.
This first supplement to the Museum of Science and Industry Basic List of Children's Science Books contains books received for the museum's 13th annual children's science book fair. Children's science books are listed under these headings: animals; astronomy; aviation and space; biography; careers; earth sciences; environment/conservation;…
Deckelbaum, Richard J; Ntambi, James M; Wolgemuth, Debra J
2011-09-01
This article provides evidence that basic science research and education should be key priorities for global health training, capacity building, and practice. Currently, there are tremendous gaps between strong science education and research in developed countries (the North) as compared to developing countries (the South). In addition, science research and education appear as low priorities in many developing countries. The need to stress basic science research beyond the typical investment of infectious disease basic service and research laboratories in developing areas is significant in terms of the benefits, not only to education, but also for economic strengthening and development of human resources. There are some indications that appreciation of basic science research education and training is increasing, but this still needs to be applied more rigorously and strengthened systematically in developing countries. Copyright © 2011 Elsevier Inc. All rights reserved.
Basic Science Training Program.
ERIC Educational Resources Information Center
Brummel, Clete
These six learning modules were developed for Lake Michigan College's Basic Science Training Program, a workshop to develop good study skills while reviewing basic science. The first module, which was designed to provide students with the necessary skills to study efficiently, covers the following topics: time management; an overview of a study…
Amaral, Margarida D; Boj, Sylvia F; Shaw, James; Leipziger, Jens; Beekman, Jeffrey M
2018-06-01
The European Cystic Fibrosis Society (ECFS) Basic Science Working Group (BSWG) organized a session on the topic "Cystic Fibrosis: Beyond the Airways", within the 15th ECFS Basic Science Conference which gathered around 200 researchers working in the basic science of CF. The session was organized and chaired by Margarida Amaral (BioISI, University of Lisboa, Portugal) and Jeffrey Beekman (University Medical Centre Utrecht, Netherlands) as Chair and Vice-Chair of the BSWG and its purpose was to bring attention of participants of the ECFS Basic Science Conference to "more forgotten" organs in CF disease. In this report we attempt to review and integrate the ideas that emerged at the session. Copyright © 2018 European Cystic Fibrosis Society. All rights reserved.
Laser Wakefield Acceleration: Structural and Dynamic Studies. Final Technical Report ER40954
DOE Office of Scientific and Technical Information (OSTI.GOV)
Downer, Michael C.
2014-04-30
Particle accelerators enable scientists to study the fundamental structure of the universe, but have become the largest and most expensive of scientific instruments. In this project, we advanced the science and technology of laser-plasma accelerators, which are thousands of times smaller and less expensive than their conventional counterparts. In a laser-plasma accelerator, a powerful laser pulse exerts light pressure on an ionized gas, or plasma, thereby driving an electron density wave, which resembles the wake behind a boat. Electrostatic fields within this plasma wake reach tens of billions of volts per meter, fields far stronger than ordinary non-plasma matter (suchmore » as the matter that a conventional accelerator is made of) can withstand. Under the right conditions, stray electrons from the surrounding plasma become trapped within these “wake-fields”, surf them, and acquire energy much faster than is possible in a conventional accelerator. Laser-plasma accelerators thus might herald a new generation of compact, low-cost accelerators for future particle physics, x-ray and medical research. In this project, we made two major advances in the science of laser-plasma accelerators. The first of these was to accelerate electrons beyond 1 gigaelectronvolt (1 GeV) for the first time. In experimental results reported in Nature Communications in 2013, about 1 billion electrons were captured from a tenuous plasma (about 1/100 of atmosphere density) and accelerated to 2 GeV within about one inch, while maintaining less than 5% energy spread, and spreading out less than ½ milliradian (i.e. ½ millimeter per meter of travel). Low energy spread and high beam collimation are important for applications of accelerators as coherent x-ray sources or particle colliders. This advance was made possible by exploiting unique properties of the Texas Petawatt Laser, a powerful laser at the University of Texas at Austin that produces pulses of 150 femtoseconds (1 femtosecond is 10-15 seconds) in duration and 150 Joules in energy (equivalent to the muzzle energy of a small pistol bullet). This duration was well matched to the natural electron density oscillation period of plasma of 1/100 atmospheric density, enabling efficient excitation of a plasma wake, while this energy was sufficient to drive a high-amplitude wake of the right shape to produce an energetic, collimated electron beam. Continuing research is aimed at increasing electron energy even further, increasing the number of electrons captured and accelerated, and developing applications of the compact, multi-GeV accelerator as a coherent, hard x-ray source for materials science, biomedical imaging and homeland security applications. The second major advance under this project was to develop new methods of visualizing the laser-driven plasma wake structures that underlie laser-plasma accelerators. Visualizing these structures is essential to understanding, optimizing and scaling laser-plasma accelerators. Yet prior to work under this project, computer simulations based on estimated initial conditions were the sole source of detailed knowledge of the complex, evolving internal structure of laser-driven plasma wakes. In this project we developed and demonstrated a suite of optical visualization methods based on well-known methods such as holography, streak cameras, and coherence tomography, but adapted to the ultrafast, light-speed, microscopic world of laser-driven plasma wakes. Our methods output images of laser-driven plasma structures in a single laser shot. We first reported snapshots of low-amplitude laser wakes in Nature Physics in 2006. We subsequently reported images of high-amplitude laser-driven plasma “bubbles”, which are important for producing electron beams with low energy spread, in Physical Review Letters in 2010. More recently, we have figured out how to image laser-driven structures that change shape while propagating in a single laser shot. The latter techniques, which use the methods of computerized tomography, were demonstrated on test objects – e.g. laser-driven filaments in air and glass – and reported in Optics Letters in 2013 and Nature Communications in 2014. Their output is a multi-frame movie rather than a snapshot. Continuing research is aimed at applying these tomographic methods directly to evolving laser-driven plasma accelerator structures in our laboratory, then, once perfected, to exporting them to plasma-based accelerator laboratories around the world as standard in-line metrology instruments.« less
Clinical Correlations as a Tool in Basic Science Medical Education
Klement, Brenda J.; Paulsen, Douglas F.; Wineski, Lawrence E.
2016-01-01
Clinical correlations are tools to assist students in associating basic science concepts with a medical application or disease. There are many forms of clinical correlations and many ways to use them in the classroom. Five types of clinical correlations that may be embedded within basic science courses have been identified and described. (1) Correlated examples consist of superficial clinical information or stories accompanying basic science concepts to make the information more interesting and relevant. (2) Interactive learning and demonstrations provide hands-on experiences or the demonstration of a clinical topic. (3) Specialized workshops have an application-based focus, are more specialized than typical laboratory sessions, and range in complexity from basic to advanced. (4) Small-group activities require groups of students, guided by faculty, to solve simple problems that relate basic science information to clinical topics. (5) Course-centered problem solving is a more advanced correlation activity than the others and focuses on recognition and treatment of clinical problems to promote clinical reasoning skills. Diverse teaching activities are used in basic science medical education, and those that include clinical relevance promote interest, communication, and collaboration, enhance knowledge retention, and help develop clinical reasoning skills. PMID:29349328
Binstock, Judith; Junsanto-Bahri, Tipsuda
2014-04-01
The relevance of current standard medical school science prerequisites is being reexamined. (1) To identify which science prerequisites are perceived to best prepare osteopathic medical students for their basic science and osteopathic manipulative medicine (OMM) coursework and (2) to determine whether science prerequisites for osteopathic medical school should be modified. Preclinical osteopathic medical students and their basic science and OMM faculty from 3 colleges of osteopathic medicine were surveyed about the importance of specific science concepts, laboratories, and research techniques to medical school coursework. Participants chose responses on a 5-point scale, with 1 indicating "strongly disagree" or "not important" and 5 indicating "strongly agree" or "extremely important." Participants were also surveryed on possible prerequisite modifications. Student responses (N=264) to the general statement regarding prerequisites were "neutral" for basic science coursework and "disagree" for OMM coursework, with mean (standard deviation [SD]) scores of 3.37 (1.1) and 2.68 (1.2), respectively. Faculty responses (N=49) were similar, with mean (SD) scores of 3.18 (1.1) for basic science coursework and 2.67 (1.2) for OMM coursework. Student mean (SD) scores were highest for general biology for basic science coursework (3.93 [1.1]) and physics for OMM coursework (2.5 [1.1]). Student mean (SD) scores were lowest for physics for basic science coursework (1.79 [1.2]) and organic chemistry for OMM coursework (1.2 [0.7]). Both basic science and OMM faculty rated general biology highest in importance (mean [SD] scores, 3.73 [0.9] and 4.22 [1.0], respectively). Students and faculty rated biochemistry high in importance for basic science coursework (mean [SD] scores of 3.66 [1.2] and 3.32 [1.2], respectively). For basic science coursework, students and faculty rated most laboratories as "important," with the highest mean (SD) ratings for general anatomy (students, 3.66 [1.5]; faculty, 3.72 [1.1]) and physiology (students, 3.56 [1.7]; faculty, 3.61 [1.1]). For their OMM coursework, students rated only general anatomy and physiology laboratories as "important" (mean [SD] scores, 3.22 [1.8] and 2.61 [1.6], respectively), whereas OMM faculty rated all laboratories as "important" (mean scores, >3). Both student and faculty respondents rated research techniques higher in importance for basic science coursework than for OMM coursework. For prerequisite modifications, all respondents indicated "no change" for biology and "reduce content" for organic chemistry and physics. All respondents favored adding physiology and biochemistry as prerequisites. General biology and laboratory were the only standard prerequisites rated as "important." Research techniques were rated as "important" for basic science coursework only. Physiology and biochemistry were identified as possible additions to prerequisites. It may be necessary for colleges of osteopathic medicine to modify science prerequisites to reflect information that is pertinent to their curricula.
10 Tips to Reduce Your Chance of Losing Vision from the Most Common Cause of Blindness
... 2019 Basic and Clinical Science Course, Section 02: Fundamentals and Principles of Ophthalmology 2018-2019 Basic and ... 2019 Basic and Clinical Science Course, Section 02: Fundamentals and Principles of Ophthalmology Print 2018-2019 Basic ...
Integration and timing of basic and clinical sciences education.
Bandiera, Glen; Boucher, Andree; Neville, Alan; Kuper, Ayelet; Hodges, Brian
2013-05-01
Medical education has traditionally been compartmentalized into basic and clinical sciences, with the latter being viewed as the skillful application of the former. Over time, the relevance of basic sciences has become defined by their role in supporting clinical problem solving rather than being, of themselves, a defining knowledge base of physicians. As part of the national Future of Medical Education in Canada (FMEC MD) project, a comprehensive empirical environmental scan identified the timing and integration of basic sciences as a key pressing issue for medical education. Using the literature review, key informant interviews, stakeholder meetings, and subsequent consultation forums from the FMEC project, this paper details the empirical basis for focusing on the role of basic science, the evidentiary foundations for current practices, and the implications for medical education. Despite a dearth of definitive relevant studies, opinions about how best to integrate the sciences remain strong. Resource allocation, political power, educational philosophy, and the shift from a knowledge-based to a problem-solving profession all influence the debate. There was little disagreement that both sciences are important, that many traditional models emphasized deep understanding of limited basic science disciplines at the expense of other relevant content such as social sciences, or that teaching the sciences contemporaneously rather than sequentially has theoretical and practical merit. Innovations in integrated curriculum design have occurred internationally. Less clear are the appropriate balance of the sciences, the best integration model, and solutions to the political and practical challenges of integrated curricula. New curricula tend to emphasize integration, development of more diverse physician competencies, and preparation of physicians to adapt to evolving technology and patients' expectations. Refocusing the basic/clinical dichotomy to a foundational/applied model may yield benefits in training widely competent future physicians.
Trends in Basic Sciences Education in Dental Schools, 1999-2016.
Lantz, Marilyn S; Shuler, Charles F
2017-08-01
The purpose of this study was to examine data published over the past two decades to identify trends in the basic sciences curriculum in dental education, provide an analysis of those trends, and compare them with trends in the basic sciences curriculum in medical education. Data published from the American Dental Association (ADA) Surveys of Dental Education, American Dental Education Association (ADEA) Surveys of Dental School Seniors, and two additional surveys were examined. In large part, survey data collected focused on the structure, content, and instructional strategies used in dental education: what was taught and how. Great variability was noted in the total clock hours of instruction and the clock hours of basic sciences instruction reported by dental schools. Moreover, the participation of medical schools in the basic sciences education of dental students appears to have decreased dramatically over the past decade. Although modest progress has been made in implementing some of the curriculum changes recommended in the 1995 Institute of Medicine report such as integrated basic and clinical sciences curricula, adoption of active learning methods, and closer engagement with medical and other health professions education programs, educational effectiveness studies needed to generate data to support evidence-based approaches to curriculum reform are lacking. Overall, trends in the basic sciences curriculum in medical education were similar to those for dental education. Potential drivers of curriculum change were identified, as was recent work in other fields that should encourage reconsideration of dentistry's approach to basic sciences education. This article was written as part of the project "Advancing Dental Education in the 21st Century."
Vink, Sylvia; van Tartwijk, Jan; Verloop, Nico; Gosselink, Manon; Driessen, Erik; Bolk, Jan
2016-08-01
To determine the content of integrated curricula, clinical concepts and the underlying basic science concepts need to be made explicit. Preconstructed concept maps are recommended for this purpose. They are mainly constructed by experts. However, concept maps constructed by residents are hypothesized to be less complex, to reveal more tacit basic science concepts and these basic science concepts are expected to be used for the organization of the maps. These hypotheses are derived from studies about knowledge development of individuals. However, integrated curricula require a high degree of cooperation between clinicians and basic scientists. This study examined whether there are consistent variations regarding the articulation of integration when groups of experienced clinicians and basic scientists and groups of residents and basic scientists-in-training construct concept maps. Seven groups of three clinicians and basic scientists on experienced level and seven such groups on resident level constructed concept maps illuminating clinical problems. They were guided by instructions that focused them on articulation of integration. The concept maps were analysed by features that described integration. Descriptive statistics showed consistent variations between the two expertise levels. The concept maps of the resident groups exceeded those of the experienced groups in articulated integration. First, they used significantly more links between clinical and basic science concepts. Second, these links connected basic science concepts with a greater variety of clinical concepts than the experienced groups. Third, although residents did not use significantly more basic science concepts, they used them significantly more frequent to organize the clinical concepts. The conclusion was drawn that not all hypotheses could be confirmed and that the resident concept maps were more elaborate than expected. This article discusses the implications for the role that residents and basic scientists-in-training might play in the construction of preconstructed concept maps and the development of integrated curricula.
A Simulation for Teaching the Basic and Clinical Science of Fluid Therapy
ERIC Educational Resources Information Center
Rawson, Richard E.; Dispensa, Marilyn E.; Goldstein, Richard E.; Nicholson, Kimberley W.; Vidal, Noni Korf
2009-01-01
The course "Management of Fluid and Electrolyte Disorders" is an applied physiology course taught using lectures and paper-based cases. The course approaches fluid therapy from both basic science and clinical perspectives. While paper cases provide a basis for application of basic science concepts, they lack key components of genuine clinical…
Integrated Medical Curriculum: Advantages and Disadvantages
Quintero, Gustavo A.; Vergel, John; Arredondo, Martha; Ariza, María-Cristina; Gómez, Paula; Pinzon-Barrios, Ana-Maria
2016-01-01
Most curricula for medical education have been integrated horizontally and vertically–-vertically between basic and clinical sciences. The Flexnerian curriculum has disappeared to permit integration between basic sciences and clinical sciences, which are taught throughout the curriculum. We have proposed a different form of integration where the horizontal axis represents the defined learning outcomes and the vertical axis represents the teaching of the sciences throughout the courses. We believe that a mere integration of basic and clinical sciences is not enough because it is necessary to emphasize the importance of humanism as well as health population sciences in medicine. It is necessary to integrate basic and clinical sciences, humanism, and health population in the vertical axis, not only in the early years but also throughout the curriculum, presupposing the use of active teaching methods based on problems or cases in small groups. PMID:29349303
The Museum of Science and Industry Basic List of Children's Science Books, 1987.
ERIC Educational Resources Information Center
Richter, Bernice, Comp.; Wenzel, Duane, Comp.
Presented is the second annual supplement to the Museum of Science and Industry Basic List of Children's Science Books 1973-1984. In this supplement, children's science books are listed under the headings of animals, astronomy, aviation and space, biography, earth sciences, encyclopedias and reference books, environment and conservation, fiction,…
NASA Astrophysics Data System (ADS)
Park, Byung Ho; Han, Yong Oun
2018-04-01
Steady variations in aerodynamic forces and flow behaviors of two-dimensional NACA0012 airfoil were investigated using a numerical method for One Revolution Angle of Attack (AOA) at Reynolds number of 105 . The profiles of lift coefficients, drag coefficients, and pressure coefficients were compared with those of the experimental data. The AERODAS model was used to analyze the profiles of lift and drag coefficients. Wake characteristics were given along with the deficit profiles of incoming velocity components. Both the characteristics of normal and reverse airfoil models were compared with the basic aerodynamic data for the same range of AOA. The results show that two peaks of the lift coefficients appeared at 11.5{°} and 42{°} and are in good agreement with the pre-stall and post-stall models, respectively. Counter-rotating vortex flows originated from the leading and trailing edges at a high AOA, which formed an impermeable zone over the suction surface and made reattachments in the wake. Moreover, the acceleration of inflow along the boundary of the vortex wrap appeared in the profile of the wake velocity. The drag profile was found to be independent of the airfoil mode, but the lift profile was quite sensitive to the airfoil mode.
Viscid-inviscid interaction associated with incompressible flow past wedges at high Reynolds number
NASA Technical Reports Server (NTRS)
Warpinski, N. R.; Chow, W. L.
1977-01-01
An analytical method is suggested for the study of the viscid inviscid interaction associated with incompressible flow past wedges with arbitrary angles. It is shown that the determination of the nearly constant pressure (base pressure) prevailing within the near wake is really the heart of the problem, and the pressure can only be established from these interactive considerations. The basic free streamline flow field is established through two discrete parameters which adequately describe the inviscid flow around the body and the wake. The viscous flow processes such as the boundary layer buildup, turbulent jet mixing, and recompression are individually analyzed and attached to the inviscid flow in the sense of the boundary layer concept. The interaction between the viscous and inviscid streams is properly displayed by the fact that the aforementioned discrete parameters needed for the inviscid flow are determined by the viscous flow condition at the point of reattachment. It is found that the reattachment point behaves as a saddle point singularity for the system of equations describing the recompressive viscous flow processes, and this behavior is exploited for the establishment of the overall flow field. Detailed results such as the base pressure, pressure distributions on the wedge, and the geometry of the wake are determined as functions of the wedge angle.
Validation of the Dynamic Wake Meander model with focus on tower loads
NASA Astrophysics Data System (ADS)
Larsen, T. J.; Larsen, G. C.; Pedersen, M. M.; Enevoldsen, K.; Madsen, H. A.
2017-05-01
This paper presents a comparison between measured and simulated tower loads for the Danish offshore wind farm Nysted 2. Previously, only limited full scale experimental data containing tower load measurements have been published, and in many cases the measurements include only a limited range of wind speeds. In general, tower loads in wake conditions are very challenging to predict correctly in simulations. The Nysted project offers an improved insight to this field as six wind turbines located in the Nysted II wind farm have been instrumented to measure tower top and tower bottom moments. All recorded structural data have been organized in a database, which in addition contains relevant wind turbine SCADA data as well as relevant meteorological data - e.g. wind speed and wind direction - from an offshore mast located in the immediate vicinity of the wind farm. The database contains data from a period extending over a time span of more than 3 years. Based on the recorded data basic mechanisms driving the increased loading experienced by wind turbines operating in offshore wind farm conditions have been identified, characterized and modeled. The modeling is based on the Dynamic Wake Meandering (DWM) approach in combination with the state-of-the-art aeroelastic model HAWC2, and has previously as well as in this study shown good agreement with the measurements. The conclusions from the study have several parts. In general the tower bending and yaw loads show a good agreement between measurements and simulations. However, there are situations that are still difficult to match. One is tower loads of single-wake operation near rated ambient wind speed for single wake situations for spacing’s around 7-8D. A specific target of the study was to investigate whether the largest tower fatigue loads are associated with a certain downstream distance. This has been identified in both simulations and measurements, though a rather flat optimum is seen in the measurements.
Nielsen, Dorte Guldbrand; Gotzsche, Ole; Sonne, Ole; Eika, Berit
2012-10-01
Two major views on the relationship between basic science knowledge and clinical knowledge stand out; the Two-world view seeing basic science and clinical science as two separate knowledge bases and the encapsulated knowledge view stating that basic science knowledge plays an overt role being encapsulated in the clinical knowledge. However, resent research has implied that a more complex relationship between the two knowledge bases exists. In this study, we explore the relationship between immediate relevant basic science (physiology) and clinical knowledge within a specific domain of medicine (echocardiography). Twenty eight medical students in their 3rd year and 45 physicians (15 interns, 15 cardiology residents and 15 cardiology consultants) took a multiple-choice test of physiology knowledge. The physicians also viewed images of a transthoracic echocardiography (TTE) examination and completed a checklist of possible pathologies found. A total score for each participant was calculated for the physiology test, and for all physicians also for the TTE checklist. Consultants scored significantly higher on the physiology test than did medical students and interns. A significant correlation between physiology test scores and TTE checklist scores was found for the cardiology residents only. Basic science knowledge of immediate relevance for daily clinical work expands with increased work experience within a specific domain. Consultants showed no relationship between physiology knowledge and TTE interpretation indicating that experts do not use basic science knowledge in routine daily practice, but knowledge of immediate relevance remains ready for use.
Crisis = Opportunity: Civic Literacy in the Wake of a Hurricane
ERIC Educational Resources Information Center
Zenyuh, Monica
2013-01-01
In this article sixth grade English/language arts and science teacher at Oldfield Middle School (Greenlawn, New York) Monica Zenyuh describes how she established a program called "Adopt-a-School" in the aftermath of Hurricane Sandy. Schools that wished to provide assistance would be matched with a grade, school, or district in devastated…
2016-09-01
AWARD NUMBER: W81XWH-13-1-0309 TITLE: Acceleration of Regeneration of Large-Gap Peripheral Nerve Injuries Using Acellular Nerve Allografts...plus amniotic Fluid Derived Stem Cells (AFS). PRINCIPAL INVESTIGATOR: Thomas L. Smith, PhD RECIPIENT: Wake Forest University Health Sciences
At Wake Forest U., Admissions Has Become "More Art than Science"
ERIC Educational Resources Information Center
Hoover, Eric
2009-01-01
The admissions process is awash in numbers. Students accumulate grade-point averages and test scores. Colleges use statistical models to predict enrollment outcomes, and they tout their place in commercial rankings. In many ways, numbers simplify this complex enterprise. However, they have come to carry undue weight, says Martha Blevins Allman,…
NASA Astrophysics Data System (ADS)
Munyeme, G.
The economic and social impact of science based technologies has become increasingly dominant in modern world The benefits are a result of combined leading-edge science and technology skills which offers opportunities for new innovations Knowledge in basic sciences has become the cornerstone of sustainable economic growth and national prosperity Unfortunately in many developing countries research and education in basic sciences are inadequate to enable science play its full role in national development For this reason most developing countries have not fully benefited from the opportunities provided by modern technologies The lack of human and financial resources is the main reason for slow transfer of scientific knowledge and technologies to developing countries Developing countries therefore need to develop viable research capabilities and knowledge in basic sciences The advert of the International Heliophysical Year IHY may provide opportunities for strengthening capacity in basic science research in developing countries Among the science goals of the IHY is the fostering of international scientific cooperation in the study of heliophysical phenomena This paper will address and provide an in depth discussion on how basic science research can be enhanced in a developing country using the framework of science goals and objectives of IHY It will further highlight the hurdles and experiences of creating in-country training capacity and research capabilities in space science It will be shown that some of these hurdles can be
Auditory Verbal Experience and Agency in Waking, Sleep Onset, REM, and Non-REM Sleep.
Speth, Jana; Harley, Trevor A; Speth, Clemens
2017-04-01
We present one of the first quantitative studies on auditory verbal experiences ("hearing voices") and auditory verbal agency (inner speech, and specifically "talking to (imaginary) voices or characters") in healthy participants across states of consciousness. Tools of quantitative linguistic analysis were used to measure participants' implicit knowledge of auditory verbal experiences (VE) and auditory verbal agencies (VA), displayed in mentation reports from four different states. Analysis was conducted on a total of 569 mentation reports from rapid eye movement (REM) sleep, non-REM sleep, sleep onset, and waking. Physiology was controlled with the nightcap sleep-wake mentation monitoring system. Sleep-onset hallucinations, traditionally at the focus of scientific attention on auditory verbal hallucinations, showed the lowest degree of VE and VA, whereas REM sleep showed the highest degrees. Degrees of different linguistic-pragmatic aspects of VE and VA likewise depend on the physiological states. The quantity and pragmatics of VE and VA are a function of the physiologically distinct state of consciousness in which they are conceived. Copyright © 2016 Cognitive Science Society, Inc.
Unsteady wake of a rotating tire
NASA Astrophysics Data System (ADS)
Lombard, Jean-Eloi; Moxey, Dave; Xu, Hui; Sherwin, Spencer; Sherwin Lab Team
2015-11-01
For open wheel race-cars, such as IndyCar and Formula One, the wheels are responsible for 40% of the total drag. For road cars drag associated to the wheels and under-carriage can represent 60% of total drag at highway cruise speeds. Experimental observations have reported two or three pairs of counter rotating vortices, the relative importance of which still remains an open question, that interact to form a complex wake. Traditional RANS based methods are typically not well equipped to deal with such highly unsteady flows which motivates research into more physical, unsteady models. Leveraging a high-fidelity spectral/hp element based method a Large Eddy Simulation is performed to give further insight into unsteady characteristics of the wake. In particular the unsteady nature of both the jetting and top vortex pair is reported as well as the time and length scales associated with the vortex core trajectories. Correlation with experimentally obtained particle image velocimetry is presented. The authors acknowledge support from the United Kingdom Turbulence Consortium (UKTC) as well as from the Engineering and Physical Sciences Research Council (EPSRC) for access to ARCHER UK National Supercomputing Service.
Everly, George S; Barnett, Daniel J; Links, Jonathan M
2012-01-01
There appears to be virtual universal endorsement of the need for and value of acute "psychological first aid" (PFA) in the wake of trauma and disasters. In this paper, we describe the development of the curriculum for The Johns Hopkins RAPID-PFA model of psychological first aid. We employed an adaptation of the basic framework for the development of a clinical science as recommended by Millon which entailed: historical review, theoretical development, and content validation. The process of content validation of the RAPID-PFA curriculum entailed the assessment of attitudes (confidence in the application of PFA interventions, preparedness in the application of PFA); knowledge related to the application of immediate mental health interventions; and behavior (the ability to recognize clinical markers in the field as assessed via a videotape recognition exercise). Results of the content validation phase suggest the six-hour RAPID-PFA curriculum, initially based upon structural modeling analysis, can improve confidence in the application of PFA interventions, preparedness in the application of PFA, knowledge related to the application of immediate mental health interventions, and the ability to recognize clinical markers in the field as assessed via a videotape recognition exercise.
NASA Astrophysics Data System (ADS)
Iungo, Giacomo Valerio; Camarri, Simone; Ciri, Umberto; El-Asha, Said; Leonardi, Stefano; Rotea, Mario A.; Santhanagopalan, Vignesh; Viola, Francesco; Zhan, Lu
2016-11-01
Site conditions, such as topography and local climate, as well as wind farm layout strongly affect performance of a wind power plant. Therefore, predictions of wake interactions and their effects on power production still remain a great challenge in wind energy. For this study, an onshore wind turbine array was monitored through lidar measurements, SCADA and met-tower data. Power losses due to wake interactions were estimated to be approximately 4% and 2% of the total power production under stable and convective conditions, respectively. This dataset was then leveraged for the calibration of a data driven RANS (DDRANS) solver, which is a compelling tool for prediction of wind turbine wakes and power production. DDRANS is characterized by a computational cost as low as that for engineering wake models, and adequate accuracy achieved through data-driven tuning of the turbulence closure model. DDRANS is based on a parabolic formulation, axisymmetry and boundary layer approximations, which allow achieving low computational costs. The turbulence closure model consists in a mixing length model, which is optimally calibrated with the experimental dataset. Assessment of DDRANS is then performed through lidar and SCADA data for different atmospheric conditions. This material is based upon work supported by the National Science Foundation under the I/UCRC WindSTAR, NSF Award IIP 1362033.
PIV study of the wake of a model wind turbine transitioning between operating set points
NASA Astrophysics Data System (ADS)
Houck, Dan; Cowen, Edwin (Todd)
2016-11-01
Wind turbines are ideally operated at their most efficient tip speed ratio for a given wind speed. There is increasing interest, however, in operating turbines at other set points to increase the overall power production of a wind farm. Specifically, Goit and Meyers (2015) used LES to examine a wind farm optimized by unsteady operation of its turbines. In this study, the wake of a model wind turbine is measured in a water channel using PIV. We measure the wake response to a change in operational set point of the model turbine, e.g., from low to high tip speed ratio or vice versa, to examine how it might influence a downwind turbine. A modified torque transducer after Kang et al. (2010) is used to calibrate in situ voltage measurements of the model turbine's generator operating across a resistance to the torque on the generator. Changes in operational set point are made by changing the resistance or the flow speed, which change the rotation rate measured by an encoder. Single camera PIV on vertical planes reveals statistics of the wake at various distances downstream as the turbine transitions from one set point to another. From these measurements, we infer how the unsteady operation of a turbine may affect the performance of a downwind turbine as its incoming flow. National Science Foundation and the Atkinson Center for a Sustainable Future.
What is Basic Research? Insights from Historical Semantics.
Schauz, Désirée
2014-01-01
For some years now, the concept of basic research has been under attack. Yet although the significance of the concept is in doubt, basic research continues to be used as an analytical category in science studies. But what exactly is basic research? What is the difference between basic and applied research? This article seeks to answer these questions by applying historical semantics. I argue that the concept of basic research did not arise out of the tradition of pure science. On the contrary, this new concept emerged in the late 19th and early 20th centuries, a time when scientists were being confronted with rising expectations regarding the societal utility of science. Scientists used the concept in order to try to bridge the gap between the promise of utility and the uncertainty of scientific endeavour. Only after 1945, when United States science policy shaped the notion of basic research, did the concept revert to the older ideals of pure science. This revival of the purity discourse was caused by the specific historical situation in the US at that time: the need to reform federal research policy after the Second World War, the new dimension of ethical dilemmas in science and technology during the atomic era, and the tense political climate during the Cold War.
Fukui, Tsuguya; Takahashi, Osamu; Rahman, Mahbubur
2013-11-01
During 1991-2000, Japan contribution to the top general medicine journals was very small although the contribution to the top basic science journals was sizeable. However, it has not been examined whether the contribution to the top general medicine and basic science journals has changed during the last decade (2001-2010). The objective of this study was to compare Japan representation in high-impact general medicine and basic science journals between the years 1991-2000 and 2001-2010. We used PubMed database to examine the frequency of articles originated from Japan and published in 7 high-impact general medicine and 6 high-impact basic science journals. Several Boolean operators were used to connect name of the journal, year of publication and corresponding authors' affiliation in Japan. Compared to the 1991-2000 decade, Japan contribution to the top general medicine journals did not increase over the 2001-2010 period (0.66% vs. 0.74%, P = 0.255). However, compared to the same period, its contribution to the top basic science journals increased during 2001-2010 (2.51% vs. 3.60%, P < 0.001). Japan representation in basic science journals showed an upward trend over the 1991-2000 period (P < 0.001) but remained flat during 2001-2010 (P = 0.177). In contrast, the trend of Japan representation in general medicine journals remained flat both during 1991-2000 (P = 0.273) and 2001-2010 (P = 0.073). Overall, Japan contribution to the top general medicine journals has remained small and unchanged over the last two decades. However, top basic science journals had higher Japan representation during 2001-2010 compared to 1991-2000.
D'Silva, Evan R; Woolfolk, Marilyn W; Duff, Renee E; Inglehart, Marita R
2018-04-01
Admitting students from non-traditional or disadvantaged backgrounds can increase the diversity of dental school classes. The aims of this study were to analyze how interested non-traditional incoming dental students were at the beginning of an academic pre-orientation program in learning about basic science, dentistry-related topics, and academic skills; how confident they were in doing well in basic science and dentistry-related courses; and how they evaluated the program at the end. The relationships between personal (interest/confidence) and structural factors (program year, number of participants) and program evaluations were also explored. All 360 students in this program at the University of Michigan from 1998 to 2016 were invited to participate in surveys at the beginning and end of the educational intervention. A total of 353 students responded at the beginning (response rate 98%), and 338 responded at the end (response rate 94%). At the beginning, students were more interested in learning about basic science and dentistry-related topics than about academic skills, and they were more confident in their dentistry- related than basic science-related abilities. At the end, students valued basic science and dentistry-related education more positively than academic skills training. Confidence in doing well and interest in basic science and dentistry-related topics were correlated. The more recent the program was, the less confident the students were in their basic science abilities and the more worthwhile they considered the program to be. The more participants the program had, the more confident the students were, and the better they evaluated their basic science and dentistry-related education. Overall, this academic pre-orientation program was positively evaluated by the participants.
Integration of Basic and Clinical Science in the Psychiatry Clerkship.
Wilkins, Kirsten M; Moore, David; Rohrbaugh, Robert M; Briscoe, Gregory W
2017-06-01
Integration of basic and clinical science is a key component of medical education reform, yet best practices have not been identified. The authors compared two methods of basic and clinical science integration in the psychiatry clerkship. Two interventions aimed at integrating basic and clinical science were implemented and compared in a dementia conference: flipped curriculum and coteaching by clinician and physician-scientist. The authors surveyed students following each intervention. Likert-scale responses were compared. Participants in both groups responded favorably to the integration format and would recommend integration be implemented elsewhere in the curriculum. Survey response rates differed significantly between the groups and student engagement with the flipped curriculum video was limited. Flipped curriculum and co-teaching by clinician and physician-scientist are two methods of integrating basic and clinical science in the psychiatry clerkship. Student learning preferences may influence engagement with a particular teaching format.
Brown, Bethanne; Skau, Kenneth; Wall, Andrea
2009-04-07
To facilitate the student's ability to make the connection of the core foundational basic science courses to the practice of pharmacy. In 2000, 10 faculty members from basic science and practice courses created and implemented an integrated Patient Care Project for which students chose a volunteer patient and completed 15 different assignments Evidence of student learning, such as grades and reflective comments along with collected evaluative data, indicated an enhancement in students' perceived understanding of the connection between basic science and patient care. The Patient Care Project provided students an opportunity to use knowledge gained in their first-year foundational courses to the care of a patient, solidifying their understanding of the connection between basic science and patient care.
Yazici, Hasan; Gogus, Feride; Esen, Fehim; Yazici, Yusuf
2014-06-01
There is concern that self-critique with authors acknowledging limitations of their work is not given due importance in scientific articles. We had the impression that this was more true for articles in basic compared with clinical science. We thus surveyed for the presence of self-critique in the discussion sections of the original articles in three rheumatology journals with attention to differences between the basic and the clinical science articles. The discussion sections of the original articles in January, May, and September 2012 issues of Annals of the Rheumatic Diseases, Arthritis and Rheumatism, and Rheumatology (Oxford) were surveyed (n = 223) after classifying each article as mainly related to clinical or basic science. The discussion sections were electronically scanned by two observers for the presence of the root word "limit" or its derivatives who also read each discussion section for the presence of any limitations otherwise voiced. A limitation discussion in any form was present in only 19 (20.2%) or 29 (30.1%) of 94 basic science vs. 95 (73.6%) or 107 (82.3%) of 129 clinical science articles (P < 0.0001 for either observer). Self-critique, especially lacking in basic science articles, should be given due attention. Copyright © 2014 Elsevier Inc. All rights reserved.
Error and its meaning in forensic science.
Christensen, Angi M; Crowder, Christian M; Ousley, Stephen D; Houck, Max M
2014-01-01
The discussion of "error" has gained momentum in forensic science in the wake of the Daubert guidelines and has intensified with the National Academy of Sciences' Report. Error has many different meanings, and too often, forensic practitioners themselves as well as the courts misunderstand scientific error and statistical error rates, often confusing them with practitioner error (or mistakes). Here, we present an overview of these concepts as they pertain to forensic science applications, discussing the difference between practitioner error (including mistakes), instrument error, statistical error, and method error. We urge forensic practitioners to ensure that potential sources of error and method limitations are understood and clearly communicated and advocate that the legal community be informed regarding the differences between interobserver errors, uncertainty, variation, and mistakes. © 2013 American Academy of Forensic Sciences.
Role of Suzanne Mubarak Science Exploration Center in Motivating Physics Learning (abstract)
NASA Astrophysics Data System (ADS)
Mohsen, Mona
2009-04-01
The role of Science Exploration centers to promote learning ``beyond school walls'' is demonstrated. The Suzane Mubarak Science Exploration Center (www.smsec.com) at Hadaek El Kobba, Cairo, was inaugurated in 1998 with the assistance of Zusane Mubarak, the first lady of Egypt and the minister of education. It was the first interactive science and technology center in Egypt. After 10 years, the number of centers has increased to 33 nationwide. Since its inauguration the center has received over 3 million visitors. Through different facilities, such as the internet, science cities, multimedia, and virtual reality programs, basic principles of science are simplified and their technological applications in our daily lives are explored. These facilities are fully equipped with new media such as video conferencing, videotapes, overhead projectors, data shows, and libraries, as well as demonstration tools for basic science. The main objectives of the science exploration centers are discussed such as: (1) curricula development for on-line learning; (2) integration of e-learning programs into basic science (physics, mathematics, chemistry, and biology) and (3) workshops and organizations for students, teachers, and communities dealing with basic science programs.
ERIC Educational Resources Information Center
Nwafor, C. E.; Umoke, C. C.
2016-01-01
This study was designed to evaluate the content adequacy and readability of approved basic science and technology textbooks in use in junior secondary schools in Nigeria. Eight research questions guided the study. The sample of the study consisted of six (6) approved basic science and technology textbooks, 30 Junior Secondary Schools randomly…
Goldenberg, Neil M; Steinberg, Benjamin E; Rutka, James T; Chen, Robert; Cabral, Val; Rosenblum, Norman D; Kapus, Andras; Lee, Warren L
2016-01-01
Physicians have traditionally been at the forefront of medical research, bringing clinical questions to the laboratory and returning with ideas for treatment. However, we have anecdotally observed a decline in the popularity of basic science research among trainees. We hypothesized that fewer resident physicians have been pursuing basic science research training over time. We examined records from residents in the Surgeon-Scientist and Clinician-Investigator programs at the University of Toronto (1987-2016). Research by residents was categorized independently by 2 raters as basic science, clinical epidemiology or education-related based on the title of the project, the name of the supervisor and Pubmed searches. The study population was divided into quintiles of time, and the proportion pursuing basic science training in each quintile was calculated. Agreement between the raters was 100%; the categorization of the research topic remained unclear in 9 cases. The proportion of trainees pursuing basic science training dropped by 60% from 1987 to 2016 ( p = 0.005). Significantly fewer residents in the Surgeon-Scientist and Clinician-Investigator Programs at the University of Toronto are pursuing training in the basic sciences as compared with previous years.
The Learning Sciences in a New Era of U.S. Nationalism
ERIC Educational Resources Information Center
Cognition and Instruction, 2017
2017-01-01
What responsibilities do researchers of learning have in the wake of Trump's election and the proliferation of far-right, populist nationalism across the globe? In this essay, we seek to prompt and engage a dialogue about the political role and responsibilities of our field at this historical moment. First, we situate the social hierarchies that…
The Case for Fiction as Qualitative Research: Towards a Non-Referential Ground for Meaning
ERIC Educational Resources Information Center
Mus, Stijn
2012-01-01
In the wake of the crisis of representation, the qualitative approaches have gained momentum within the social sciences. This crisis has lead to a widespread awareness about the need to incorporate the subject's understanding in the research design. Yet, the validity of qualitative accounts is still regarded as a function of its representative…
ERIC Educational Resources Information Center
Watts, Velma Gibson; And Others
1989-01-01
Data were gathered from participants in a summer program at the Bowman Gray School of Medicine of Wake Forest University. This program was designed for academically talented minority students to promote their awareness of medicine as a potential career and to strengthen their science and mathematics backgrounds. (Author/MLW)
Two Decades after: "After the Wake--Postpositivistic Educational Thought"
ERIC Educational Resources Information Center
Phillips, D. C.
2004-01-01
This essay is an updating of one that was published exactly two decades ago; in the intervening years there has been a revival of interest in positivism as a historical phenomenon in epistemology and philosophy of science (some references to which are given), but there also has been heightened awareness of the various weaknesses of the positivist…
FWP executive summaries: basic energy sciences materials sciences and engineering program (SNL/NM).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Samara, George A.; Simmons, Jerry A.
2006-07-01
This report presents an Executive Summary of the various elements of the Materials Sciences and Engineering Program which is funded by the Division of Materials Sciences and Engineering, Office of Basic Energy Sciences, U.S. Department of Energy at Sandia National Laboratories, New Mexico. A general programmatic overview is also presented.
Pathophysiology of depression: role of sleep and the melatonergic system.
Srinivasan, Venkataramanujan; Pandi-Perumal, Seithikurippu R; Trakht, Ilya; Spence, D Warren; Hardeland, Ruediger; Poeggeler, Burkhard; Cardinali, Daniel P
2009-02-28
Profound disturbances in sleep architecture occur in major depressive disorders (MDD) and in bipolar affective disorders. Reduction in slow wave sleep, decreased latency of rapid eye movement (REM) sleep and abnormalities in the timing of REM/non-REM sleep cycles have all been documented in patients with MDD. It is thus evident that an understanding of the basic mechanisms of sleep regulation is essential for an analysis of the pathophysiology of depressive disorders. The suprachiasmatic nucleus (SCN), which functions as the body's master circadian clock, plays a major role in the regulation of the sleep/wakefulness rhythm and interacts actively with the homeostatic processes that regulate sleep. The control of melatonin secretion by the SCN, the occurrence of high concentrations of melatonin receptors in the SCN, and the suppression of electrical activity in the SCN by melatonin all underscore the major influence which this neurohormone has in regulating the sleep/wake cycle. The transition from wakefulness to high sleep propensity is associated with the nocturnal rise of endogenous melatonin secretion. Various lines of evidence show that depressed patients exhibit disturbances in both the amplitude and shape of the melatonin secretion rhythm and that melatonin can improve the quality of sleep in these patients. The choice of a suitable antidepressant that improves sleep quality is thus important while treating a depressive disorder. The novel antidepressant agomelatine, which combines the properties of a 5-HT(2C) antagonist and a melatonergic MT(1)/MT(2) receptor agonist, has been found very effective for resetting the disturbed sleep/wake cycle and in improving the clinical status of MDD. Agomelatine has also been found useful in treating sleep problems and improving the clinical status of patients suffering from seasonal affective disorder.
ERIC Educational Resources Information Center
Kabat, Hugh F.; And Others
The areas of basic science pharmacy instruction and clinical pharmacy practice and their interrelationships were identified in order to help develop didactic and clinical experience alternatives. A 10-member advisory committee ranked basic pharmaceutical science topical areas in terms of their applicability to clinical practice utilizing a Delphi…
Basic Research in the United States.
ERIC Educational Resources Information Center
Handler, Philip
1979-01-01
Presents a discussion of the development of basic research in the U.S. since World War II. Topics include the creation of the federal agencies, physics and astronomy, chemistry, earth science, life science, the environment, and social science. (BB)
A catalogue of devices applicable to the measurement of boundary layers and wakes on flight vehicles
NASA Technical Reports Server (NTRS)
Miley, S. J.
1972-01-01
A literature search was conducted to assemble a catalog of devices and techniques which have possible application to boundary layer and wake measurements on flight vehicles. The indices used in the search were NACA, NASA STAR, IAA, USGRDR and Applied Science and Technology Index. The period covered was 1950 through 1970. The devices contained in the catalog were restricted to those that provided essentially direct measurement of velocities, pressures and shear stresses. Pertinent material was included in the catalog if it contained either an adequate description of a device and associated performance data or a presentation of applicable information on a particular measurement theory and/or technique. When available, illustrations showing the configuration of the device and test condition data were also included.
26 CFR 1.41-5A - Basic research for taxable years beginning before January 1, 1987.
Code of Federal Regulations, 2010 CFR
2010-04-01
... was for basic research performed in the United States). (2) Research in the social sciences or humanities. Basic research does not include research in the social sciences or humanities, within the meaning...
26 CFR 1.41-5A - Basic research for taxable years beginning before January 1, 1987.
Code of Federal Regulations, 2011 CFR
2011-04-01
... was for basic research performed in the United States). (2) Research in the social sciences or humanities. Basic research does not include research in the social sciences or humanities, within the meaning...
26 CFR 1.41-5A - Basic research for taxable years beginning before January 1, 1987.
Code of Federal Regulations, 2014 CFR
2014-04-01
... was for basic research performed in the United States). (2) Research in the social sciences or humanities. Basic research does not include research in the social sciences or humanities, within the meaning...
26 CFR 1.41-5A - Basic research for taxable years beginning before January 1, 1987.
Code of Federal Regulations, 2013 CFR
2013-04-01
... was for basic research performed in the United States). (2) Research in the social sciences or humanities. Basic research does not include research in the social sciences or humanities, within the meaning...
26 CFR 1.41-5A - Basic research for taxable years beginning before January 1, 1987.
Code of Federal Regulations, 2012 CFR
2012-04-01
... was for basic research performed in the United States). (2) Research in the social sciences or humanities. Basic research does not include research in the social sciences or humanities, within the meaning...
Can Basic Research on Children and Families Be Useful for the Policy Process?
ERIC Educational Resources Information Center
Moore, Kristin A.
Based on the assumption that basic science is the crucial building block for technological and biomedical progress, this paper examines the relevance for public policy of basic demographic and behavioral sciences research on children and families. The characteristics of basic research as they apply to policy making are explored. First, basic…
Emerging therapeutics in sleep.
Saper, Clifford B; Scammell, Thomas E
2013-09-01
The development of new therapeutics for sleep disorders is increasingly dependent upon understanding the basic brain circuitry that underlies sleep-wake regulation, and how it may be pharmacologically manipulated. In this review, we consider the pathophysiological basis of major sleep disorders that often are seen by neurologists, including excessive daytime sleepiness, insomnia, narcolepsy, rapid eye movement sleep behavior disorder, and restless legs syndrome, as well as circadian disorders, and we review the current and potential future therapeutic approaches. Copyright © 2013 American Neurological Association.
[Platforms are needed for innovative basic research in ophthalmology].
Wang, Yi-qiang
2012-07-01
Basic research poses the cornerstone of technical innovation in all lines including medical sciences. Currently, there are shortages of professional scientists as well as technical supporting teams and facilities in the field of basic research of ophthalmology and visual science in China. Evaluation system and personnel policies are not supportive for innovative but high-risk-of-failure research projects. Discussion of reasons and possible solutions are given here to address these problems, aiming at promoting buildup of platforms hosting novel and important basic research in eye science in this country.
Aerodynamic Tests on a Static California Sea Lion Flipper
NASA Astrophysics Data System (ADS)
Kulkarni, Aditya A.; Leftwich, Megan C.
2017-11-01
Unlike most biological swimmers that use BCF swimming, the California sea lion relies on its foreflippers for thrust production. This unique swimming style, which lacks a characteristic oscillation frequency, allows the sea lion to leave less traceable wake while also producing high amounts of thrust. While the swimming energetics of the animal have been studied, almost nothing is known about the fluid dynamics of the system. To overcome this lack of basic understanding, a three-dimensional model of the flipper was developed using structured light-based scanners. Cross sections of the flipper model resemble the shape of the airfoils typically found in wings with thickness ratios, 11% - 37%. Wind tunnel testing conducted on static flipper revealed that positive lift was being generated at negative angles of attack. This is hypothesized to help the sea lions considerably in perform tight maneuvers with a small turning radius. The wake structure downstream of the flipper was captured using Particle Image Velocimetry (PIV).
ERIC Educational Resources Information Center
National Science Foundation, Washington, DC. National Science Board.
A survey was conducted by the National Science Board of the basic research supported by executive branch agencies of the federal government. Most of the data came from information solicited by the Board from federal agencies involved in science. Fourteen mission agencies and two agencies not so classified and 20 subunits of these responded.…
Lisk, Kristina; Agur, Anne M R; Woods, Nicole N
2017-12-01
Several studies have shown that cognitive integration of basic and clinical sciences supports diagnostic reasoning in novices; however, there has been limited exploration of the ways in which educators can translate this model of mental activity into sound instructional strategies. The use of self-explanation during learning has the potential to promote and support the development of integrated knowledge by encouraging novices to elaborate on the causal relationship between clinical features and basic science mechanisms. To explore the effect of this strategy, we compared diagnostic efficacy of teaching students (n = 71) the clinical features of four musculoskeletal pathologies using either (1) integrated causal basic science descriptions (BaSci group); (2) integrated causal basic science descriptions combined with self-explanation prompts (SE group); (3) basic science mechanisms segregated from the clinical features (SG group). All participants completed a diagnostic accuracy test immediately after learning and 1-week later. The results showed that the BaSci group performed significantly better compared to the SE (p = 0.019) and SG groups (p = 0.004); however, no difference was observed between the SE and SG groups (p = 0.91). We hypothesize that the structure of the self-explanation task may not have supported the development of a holistic conceptual understanding of each disease. These findings suggest that integration strategies need to be carefully structured and applied in ways that support the holistic story created by integrated basic science instruction in order to foster conceptual coherence and to capitalize on the benefits of cognition integration.
Exploring Attractiveness of the Basic Sciences for Female Physicians.
Yamazaki, Yuka; Fukushima, Shinji; Kozono, Yuki; Uka, Takanori; Marui, Eiji
2018-01-01
In Japan, traditional gender roles of women, especially the role of motherhood, may cause early career resignations in female physicians and a shortage of female researchers. Besides this gender issue, a general physician shortage is affecting basic science fields. Our previous study suggested that female physicians could be good candidates for the basic sciences because such work offers good work-life balance. However, the attractiveness for female physicians of working in the basic sciences, including work-life balance, is not known. In a 2012 nationwide cross-sectional questionnaire survey, female physicians holding tenured positions in the basic sciences at Japan's medical schools were asked an open-ended question about positive aspects of basic sciences that clinical medicine lacks, and we analyzed 58 respondents' comments. Qualitative analysis using the Kawakita Jiro method revealed four positive aspects: research attractiveness, priority on research productivity, a healthy work-life balance, and exemption from clinical duties. The most consistent positive aspect was research attractiveness, which was heightened by medical knowledge and clinical experience. The other aspects were double-edged swords; for example, while the priority on research productivity resulted in less gender segregation, it sometimes created tough competition, and while exemption from clinical duties contributed to a healthy work-life balance, it sometimes lowered motivation as a physician and provided unstable income. Overall, if female physicians lack an intrinsic interest in research and seek good work-life balance, they may drop out of research fields. Respecting and cultivating students' research interest is critical to alleviating the physician shortage in the basic sciences.
Gender, Science, & the Undergraduate Curriculum. Building Two-Way Streets.
ERIC Educational Resources Information Center
Musil, Caryn McTighe, Ed.
In the essays in this book interdisciplinary groups of scholars and teachers explore ways to integrate the feminist science studies scholarship into the teaching of basic science and how to insert more basic science into the teaching of women's studies. The essays of part 1, New Courses and New Intellectual Frameworks: Transforming Courses in…
ERIC Educational Resources Information Center
Demaray, Bryan
Five packets comprise the marine science component of an enrichment program for gifted elementary students. Considered in the introductory section are identification (pre/post measure) procedures. Remaining packets address the following topics (subtopics in parentheses): basic marine science laboratory techniques (microscope techniques and metric…
Ginzburg, Samara B; Brenner, Judith; Cassara, Michael; Kwiatkowski, Thomas; Willey, Joanne M
2017-01-01
There has been a call for increased integration of basic and clinical sciences during preclinical years of undergraduate medical education. Despite the recognition that clinical simulation is an effective pedagogical tool, little has been reported on its use to demonstrate the relevance of basic science principles to the practice of clinical medicine. We hypothesized that simulation with an integrated science and clinical debrief used with early learners would illustrate the importance of basic science principles in clinical diagnosis and management of patients. Small groups of first- and second-year medical students were engaged in a high-fidelity simulation followed by a comprehensive debrief facilitated by a basic scientist and clinician. Surveys including anchored and open-ended questions were distributed at the conclusion of each experience. The majority of the students agreed that simulation followed by an integrated debrief illustrated the clinical relevance of basic sciences (mean ± standard deviation: 93.8% ± 2.9% of first-year medical students; 96.7% ± 3.5% of second-year medical students) and its importance in patient care (92.8% of first-year medical students; 90.4% of second-year medical students). In a thematic analysis of open-ended responses, students felt that these experiences provided opportunities for direct application of scientific knowledge to diagnosis and treatment, improving student knowledge, simulating real-world experience, and developing clinical reasoning, all of which specifically helped them understand the clinical relevance of basic sciences. Small-group simulation followed by a debrief that integrates basic and clinical sciences is an effective means of demonstrating the relationship between scientific fundamentals and patient care for early learners. As more medical schools embrace integrated curricula and seek opportunities for integration, our model is a novel approach that can be utilized.
The development of methods for predicting and measuring distribution patterns of aerial sprays
NASA Technical Reports Server (NTRS)
Ormsbee, A. I.; Bragg, M. B.; Maughmer, M. D.
1979-01-01
The capability of conducting scale model experiments which involve the ejection of small particles into the wake of an aircraft close to the ground is developed. A set of relationships used to scale small-sized dispersion studies to full-size results are experimentally verified and, with some qualifications, basic deposition patterns are presented. In the process of validating these scaling laws, the basic experimental techniques used in conducting such studies, both with and without an operational propeller, were developed. The procedures that evolved are outlined. The envelope of test conditions that can be accommodated in the Langley Vortex Research Facility, which were developed theoretically, are verified using a series of vortex trajectory experiments that help to define the limitations due to wall interference effects for models of different sizes.
ERIC Educational Resources Information Center
Maherally, Uzma Nooreen
2014-01-01
The purpose of this study was to develop and validate a science assessment tool termed the Life Sciences Assessment (LSA) in order to assess preschool children's conceptions of basic life sciences. The hypothesis was that the four sub-constructs, each of which can be measured through a series of questions on the LSA, will make a significant…
Information-seeking behavior of basic science researchers: implications for library services.
Haines, Laura L; Light, Jeanene; O'Malley, Donna; Delwiche, Frances A
2010-01-01
This study examined the information-seeking behaviors of basic science researchers to inform the development of customized library services. A qualitative study using semi-structured interviews was conducted on a sample of basic science researchers employed at a university medical school. The basic science researchers used a variety of information resources ranging from popular Internet search engines to highly technical databases. They generally relied on basic keyword searching, using the simplest interface of a database or search engine. They were highly collegial, interacting primarily with coworkers in their laboratories and colleagues employed at other institutions. They made little use of traditional library services and instead performed many traditional library functions internally. Although the basic science researchers expressed a positive attitude toward the library, they did not view its resources or services as integral to their work. To maximize their use by researchers, library resources must be accessible via departmental websites. Use of library services may be increased by cultivating relationships with key departmental administrative personnel. Despite their self-sufficiency, subjects expressed a desire for centralized information about ongoing research on campus and shared resources, suggesting a role for the library in creating and managing an institutional repository.
Information-seeking behavior of basic science researchers: implications for library services
Haines, Laura L.; Light, Jeanene; O'Malley, Donna; Delwiche, Frances A.
2010-01-01
Objectives: This study examined the information-seeking behaviors of basic science researchers to inform the development of customized library services. Methods: A qualitative study using semi-structured interviews was conducted on a sample of basic science researchers employed at a university medical school. Results: The basic science researchers used a variety of information resources ranging from popular Internet search engines to highly technical databases. They generally relied on basic keyword searching, using the simplest interface of a database or search engine. They were highly collegial, interacting primarily with coworkers in their laboratories and colleagues employed at other institutions. They made little use of traditional library services and instead performed many traditional library functions internally. Conclusions: Although the basic science researchers expressed a positive attitude toward the library, they did not view its resources or services as integral to their work. To maximize their use by researchers, library resources must be accessible via departmental websites. Use of library services may be increased by cultivating relationships with key departmental administrative personnel. Despite their self-sufficiency, subjects expressed a desire for centralized information about ongoing research on campus and shared resources, suggesting a role for the library in creating and managing an institutional repository. PMID:20098658
Speaking of food: connecting basic and applied plant science.
Gross, Briana L; Kellogg, Elizabeth A; Miller, Allison J
2014-10-01
The Food and Agriculture Organization (FAO) predicts that food production must rise 70% over the next 40 years to meet the demands of a growing population that is expected to reach nine billion by the year 2050. Many facets of basic plant science promoted by the Botanical Society of America are important for agriculture; however, more explicit connections are needed to bridge the gap between basic and applied plant research. This special issue, Speaking of Food: Connecting Basic and Applied Plant Science, was conceived to showcase productive overlaps of basic and applied research to address the challenges posed by feeding billions of people and to stimulate more research, fresh connections, and new paradigms. Contributions to this special issue thus illustrate some interactive areas of study in plant science-historical and modern plant-human interaction, crop and weed origins and evolution, and the effects of natural and artificial selection on crops and their wild relatives. These papers provide examples of how research integrating the basic and applied aspects of plant science benefits the pursuit of knowledge and the translation of that knowledge into actions toward sustainable production of crops and conservation of diversity in a changing climate. © 2014 Botanical Society of America, Inc.
In defense of basic science funding: today's scientific discovery is tomorrow's medical advance.
Tessier-Lavigne, Marc
2013-06-01
In this address, I will discuss the importance of basic science in tackling our health problems. I will also describe how the funding cuts are damaging our economic competitiveness and turning our young people away from science.
Basic science in a predoctoral family practice curriculum.
Davies, T C; Barnett, B L
1978-02-01
A course in applied basic science was designed with topic material organized according to anatomic body regions. Details of the diagnostic method were explained early in the course, and clinical procedures for data gathering and problem analyzing were followed while the significance of basic science knowledge in dealing with clinical situations was described. A collection of 35mm slides constituted the focal point of the course. The authors conducted the course together and an atmosphere of intellectual honesty was developed through open discussion between faculty and students. Student curiosity was respected and rewarded. Summaries of the discussions were prepared retrospectively by the faculty instructors for review gy the students. This experience proved that family physicians can demonstrate effectively the relevance of basic science to clinical medicine.
Definition of Atmospheric Science Experiments and Techniques: Wake Zone Mapping Experiments
NASA Technical Reports Server (NTRS)
Taeusch, D. R.
1976-01-01
The development of a subsatellite system has been proposed for the shuttle program which would provide to the scientific community a platform for experiments which would be tethered to the shuttle spacecraft orbiting at about 200 km altitude. Experiments which can perform measurements of aeronomic interest onboard or utilizing the tethered satellite concept are described and recommended.
ERIC Educational Resources Information Center
Sigþórsson, Rúnar
2017-01-01
In the wake of a White Paper on Education Reform, published in 2014 by the Icelandic Ministry of Education, Science and Culture, the minister launched a national initiative to improve literacy education in Icelandic compulsory schools. The White Paper and the national initiative came as a reaction to the disappointing performance of 15-year-olds…
Basic Energy Sciences FY 2011 Research Summaries
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
This report provides a collection of research abstracts for more than 1,300 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2011 at some 180 institutions across the U.S. This volume is organized along the three BES divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.
ERIC Educational Resources Information Center
Maza, Paul; Miller, Allison; Carson, Brian; Hermanson, John
2018-01-01
Learning and retaining science content may be increased by applying the basic science material to real-world situations. Discussing cases with students during lectures and having them participate in laboratory exercises where they apply the science content to practical situations increases students' interest and enthusiasm. A summer course in…
Basic Energy Sciences FY 2012 Research Summaries
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
This report provides a collection of research abstracts and highlights for more than 1,400 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2012 at some 180 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.
Basic Energy Sciences FY 2014 Research Summaries
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
This report provides a collection of research abstracts and highlights for more than 1,200 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2014 at some 200 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.
The Impact of Hands-On-Approach on Student Academic Performance in Basic Science and Mathematics
ERIC Educational Resources Information Center
Ekwueme, Cecilia O.; Ekon, Esther E.; Ezenwa-Nebife, Dorothy C.
2015-01-01
Children can learn mathematics and sciences effectively even before being exposed to formal school curriculum if basic Mathematics and Sciences concepts are communicated to them early using activity oriented (Hands-on) method of teaching. Mathematics and Science are practical and activity oriented and can best be learnt through inquiry (Okebukola…
Basic Principles of Animal Science. Reprinted.
ERIC Educational Resources Information Center
Florida State Dept. of Education, Tallahassee.
The reference book is designed to fulfill the need for organized subject matter dealing with basic principles of animal science to be incorporated into the high school agriculture curriculum. The material presented is scientific knowledge basic to livestock production. Five units contain specific information on the following topics: anatomy and…
Radiological Dispersion Devices and Basic Radiation Science
ERIC Educational Resources Information Center
Bevelacqua, Joseph John
2010-01-01
Introductory physics courses present the basic concepts of radioactivity and an overview of nuclear physics that emphasizes the basic decay relationship and the various types of emitted radiation. Although this presentation provides insight into radiological science, it often fails to interest students to explore these concepts in a more rigorous…
Spinal cord injury: promising interventions and realistic goals.
McDonald, John W; Becker, Daniel
2003-10-01
Long regarded as impossible, spinal cord repair is approaching the realm of reality as efforts to bridge the gap between bench and bedside point to novel approaches to treatment. It is important to recognize that the research playing field is rapidly changing and that new mechanisms of resource development are required to effectively make the transition from basic science discoveries to effective clinical treatments. This article reviews recent laboratory studies and phase 1 clinical trials in neural and nonneural cell transplantation, stressing that the transition from basic science to clinical applications requires a parallel rather than serial approach, with continuous, two-way feedback to most efficiently translate basic science findings, through evaluation and optimization, to clinical treatments. An example of mobilizing endogenous stem cells for repair is reviewed, with emphasis on the rapid application of basic science to clinical therapy. Successful and efficient transition from basic science to clinical applications requires (1) a parallel rather than a serial approach; (2) development of centers that integrate three spheres of science, translational, transitional, and clinical trials; and (3) development of novel resources to fund the most critically limited step of transitional to clinical trials.
Ferrer, Rebecca A.; McDonald, Paige Green; Barrett, Lisa Feldman
2015-01-01
Cancer control research involves the conduct of basic and applied behavioral and social sciences to reduce cancer incidence, morbidity, and mortality, and improve quality of life. Given the importance of behavior in cancer control, fundamental research is necessary to identify psychological mechanisms underlying cancer risk, prevention, and management behaviors. Cancer prevention, diagnosis, and treatment are often emotionally-laden. As such, affective science research to elucidate questions related to basic phenomenological nature of emotion, stress, and mood is necessary to understand how cancer control can be hindered or facilitated by emotional experiences. To date, the intersection of basic affective science research and cancer control remains largely unexplored. The goal of this paper is to outline key questions in the cancer control research domain that provide an ecologically valid context for new affective science discoveries. We also provide examples of ways in which basic affective discoveries could inform future cancer prevention and control research. These examples are not meant to be exhaustive or prescriptive, but instead are offered to generate creative thought about the promise of a cancer research context for answering basic affective science questions. Together, these examples provide a compelling argument for fostering collaborations between affective and cancer control scientists. PMID:25987511
75 FR 27547 - Notice of Reestablishment of the Secretary of Energy Advisory Board
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-17
... management, basic science, research, development and technology activities; energy and national security... basis of their broad competence in areas relating to quality management, basic science, renewable energy, energy policy, environmental science, economics, and broad public policy interests. Membership of the...
Hoffman, Steve G
2015-04-01
Some scholars dismiss the distinction between basic and applied science as passé, yet substantive assumptions about this boundary remain obdurate in research policy, popular rhetoric, the sociology and philosophy of science, and, indeed, at the level of bench practice. In this article, I draw on a multiple ontology framework to provide a more stable affirmation of a constructivist position in science and technology studies that cannot be reduced to a matter of competing perspectives on a single reality. The analysis is grounded in ethnographic research in the border zone of Artificial Intelligence science. I translate in-situ moments in which members of neighboring but differently situated labs engage in three distinct repertoires that render the reality of basic and applied science: partitioning, flipping, and collapsing. While the essences of scientific objects are nowhere to be found, the boundary between basic and applied is neither illusion nor mere propaganda. Instead, distinctions among scientific knowledge are made real as a matter of course.
Dennis, Matthew J
2010-05-01
It is the premise of this paper that the need for medical and basic science instruction in dentistry will increase over time. However, student and faculty appreciation of the relevance and significance of medicine and basic science to clinical dentistry has been elusive, largely due to difficulties linking biomedical science instruction and clinical dental instruction. The scope of traditional procedure based oral surgery instruction can be expanded in an attempt to bridge the medical science-clinical gap. Topics such as health status evaluation, medical risk assessment, and a variety of other biomedical issues can be presented to students in a way which imparts specific dental meaning to basic medical science in real-life clinical situations. Using didactic and chair side instruction in an oral surgery clinical environment, students are confronted with the need to understand these issues and how they relate to the patients they encounter who present for dental care.
ERIC Educational Resources Information Center
Fernandes, Ruben; Correia, Rossana; Fonte, Rosalia; Prudencio, Cristina
2006-01-01
Health science education is presently in discussion throughout Europe due to the Bologna Declaration. Teaching basic sciences such as biochemistry in a health sciences context, namely in allied heath education, can be a challenging task since the students of preclinical health sciences are not often convinced that basic sciences are clinically…
NASA Astrophysics Data System (ADS)
Buxner, Sanlyn; Impey, Chris David; Follette, Katherine B.; Dokter, Erin F.; McCarthy, Don; Vezino, Beau; Formanek, Martin; Romine, James M.; Brock, Laci; Neiberding, Megan; Prather, Edward E.
2017-01-01
Introductory astronomy courses often serve as terminal science courses for non-science majors and present an opportunity to assess non future scientists’ attitudes towards science as well as basic scientific knowledge and scientific analysis skills that may remain unchanged after college. Through a series of studies, we have been able to evaluate students’ basic science knowledge, attitudes towards science, quantitative literacy, and informational literacy. In the Fall of 2015, we conducted a case study of a single class administering all relevant surveys to an undergraduate class of 20 students. We will present our analysis of trends of each of these studies as well as the comparison case study. In general we have found that students basic scientific knowledge has remained stable over the past quarter century. In all of our studies, there is a strong relationship between student attitudes and their science and quantitative knowledge and skills. Additionally, students’ information literacy is strongly connected to their attitudes and basic scientific knowledge. We are currently expanding these studies to include new audiences and will discuss the implications of our findings for instructors.
NASA Astrophysics Data System (ADS)
Ponomarjov, Maxim G.
2001-06-01
A method is developed that allows the numerical and analytical description of the effects of ambient magnetic field on the time-dependent 3D structures of space plasma flows due to bodies in motion through a plasma. Some of these effects have been observed in space and ionosphere as stratified, flute and yacht sail like structures of plasma disturbances, jets, wakes and clouds. The method can be used for the simulations of Solar Wind flow taking into account the magnetic field effects and the interactions with the Interstellar Medium. These problems are of practical interest in fluid mechanics, space sciences, astrophysics, in turbulence theory. They also have some fundamental interest in their own right, as they enable one to concentrate on the effects of the ambient electric and magnetic fields.
DaRosa, D A; Shuck, J M; Biester, T W; Folse, R
1993-01-01
This research sought to identify the strengths and weakness in residents' basic science knowledge and, second, to determine whether they progressively improve in their abilities to recall basic science information and clinical management facts, to analyze cause-effect relationships, and to solve clinical problems. Basic science knowledge was assessed by means of the results of the January 1990 American Board of Surgery's In-Training/Surgical Basic Science Exam (IT/SBSE). Postgraduate year (PGY) 1 residents' scores were compared with those of PGY5 residents. Content related to a question was considered "known" if 67% or more of the residents in each of the two groups answered it correctly. Findings showed 44% of the content tested by the basic science questions were unknown by new and graduating residents. The second research question required the 250 IT/SBSE questions to be classified into one of three levels of thinking abilities: recall, analysis, and inferential thinking. Profile analysis (split-plot analysis of variance) for each pair of resident levels indicated significant (P < 0.001) differences in performance on questions requiring factual recall, analysis, and inference between all levels except for PGY3s and PGY4s. The results of this research enable program directors to evaluate strengths and weaknesses in residency training curricula and the cognitive development of residents.
[Ortega and the theory of relativity].
González de Posada, Francisco
2006-01-01
Ortega y Gasset's thinking on Einstein and relativity, set out in the course of his extensive works, is constructed in the light of three of his fundamental ideas: 1) science, a special form of belief; 2) physics, a science par excellence; and 3) relativity, the intellectual fact of the highest order of its time; dedicating special attention to the essay: "The historical meaning of Einstein's theory". And it is completed with his critical attitude to the so-called "fundamental crisis" and his diagnosis of the grave problems suffered by physics in the wake of the relativistic and quantum revolutions.
Questions raised over future of UK research council
NASA Astrophysics Data System (ADS)
Banks, Michael
2010-02-01
Five senior physicists have written to the UK science minister, Lord Drayson, about the "dismal future" for researchers in the country in the wake of a £40m shortfall in the budget of the Science and Technology Facilities Council (STFC). The physicists, who chair the STFC's five advisory panels, have also called for structural reforms to be made to the council. They warn that unless the government takes action to reverse the situation, the UK will be "perceived as an untrustworthy partner in global projects" and predict that a brain drain of the best UK scientists to positions overseas will ensue.
The Development of Clinical Reasoning Skills: A Major Objective of the Anatomy Course
ERIC Educational Resources Information Center
Elizondo-Omana, Rodrigo E.; Lopez, Santos Guzman
2008-01-01
Traditional medical school curricula have made a clear demarcation between the basic biomedical sciences and the clinical years. It is our view that a comprehensive medical education necessarily involves an increased correlation between basic science knowledge and its clinical applications. A basic anatomy course should have two main objectives:…
Teaching Basic Probability in Undergraduate Statistics or Management Science Courses
ERIC Educational Resources Information Center
Naidu, Jaideep T.; Sanford, John F.
2017-01-01
Standard textbooks in core Statistics and Management Science classes present various examples to introduce basic probability concepts to undergraduate business students. These include tossing of a coin, throwing a die, and examples of that nature. While these are good examples to introduce basic probability, we use improvised versions of Russian…
Grønli, Janne; Rempe, Michael J; Clegern, William C; Schmidt, Michelle; Wisor, Jonathan P
2016-06-01
Markers of sleep drive (<10 Hz; slow-wave activity and theta) have been identified in the course of slow-wave sleep and wakefulness. So far, higher frequencies in the waking electroencephalogram have not been examined thoroughly as a function of sleep drive. Here, electroencephalogram dynamics were measured in epochs of active wake (wake characterized by high muscle tone) or quiet wake (wake characterized by low muscle tone). It was hypothesized that the higher beta oscillations (15-35 Hz, measured by local field potential and electroencephalography) represent fundamentally different processes in active wake and quiet wake. In active wake, sensory stimulation elevated beta activity in parallel with gamma (80-90 Hz) activity, indicative of cognitive processing. In quiet wake, beta activity paralleled slow-wave activity (1-4 Hz) and theta (5-8 Hz) in tracking sleep need. Cerebral lactate concentration, a measure of cerebral glucose utilization, increased during active wake whereas it declined during quiet wake. Mathematical modelling of state-dependent dynamics of cortical lactate concentration was more precisely predictive when quiet wake and active wake were included as two distinct substates rather than a uniform state of wakefulness. The extent to which lactate concentration declined in quiet wake and increased in active wake was proportionate to the amount of beta activity. These data distinguish quiet wake from active wake. Quiet wake, particularly when characterized by beta activity, is permissive to metabolic and electrophysiological changes that occur in slow-wave sleep. These data urge further studies on state-dependent beta oscillations across species. © 2016 European Sleep Research Society.
Basic Curriculum Guide--Science. Grades K-6.
ERIC Educational Resources Information Center
Starr, John W., 3rd., Ed.
GRADES OR AGES: K-6. SUBJECT MATTER: Science. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is in two parts--the background, philosophy, and instructional principles of science teaching, including a resource unit model, and the development by grade level of the various basic scientific concepts. The guide also includes information of…
Inventory of Data Sources in Science and Technology. A Preliminary Survey.
ERIC Educational Resources Information Center
International Council of Scientific Unions, Paris (France).
Provided in this inventory are sources of numerical or factual data in selected fields of basic science and applied science/technology. The objective of the inventory is to provide organizations and individuals (scientists, engineers, and information specialists), particularly those in developing countries, with basic data sources relevant to…
Eisenbarth, Sophie; Tilling, Thomas; Lueerss, Eva; Meyer, Jelka; Sehner, Susanne; Guse, Andreas H; Guse Nee Kurré, Jennifer
2016-04-29
Heterogeneous basic science knowledge of medical students is an important challenge for medical education. In this study, the authors aimed at exploring the value and role of integrated supportive science (ISS) courses as a novel approach to address this challenge and to promote learning basic science concepts in medical education. ISS courses were embedded in a reformed medical curriculum. The authors used a mixed methods approach including four focus groups involving ISS course lecturers and students (two each), and five surveys of one student cohort covering the results of regular student evaluations including the ISS courses across one study year. They conducted their study at the University Medical Center Hamburg-Eppendorf between December 2013 and July 2014. Fourteen first-year medical students and thirteen ISS course lecturers participated in the focus groups. The authors identified several themes focused on the temporal integration of ISS courses into the medical curriculum, the integration of ISS course contents into core curriculum contents, the value and role of ISS courses, and the courses' setting and atmosphere. The integrated course concept was positively accepted by both groups, with participants suggesting that it promotes retention of basic science knowledge. Values and roles identified by focus group participants included promotion of basic understanding of science concepts, integration of foundational and applied learning, and maximization of students' engagement and motivation. Building close links between ISS course contents and the core curriculum appeared to be crucial. Survey results confirmed qualitative findings regarding students' satisfaction, with some courses still requiring optimization. Integration of supportive basic science courses, traditionally rather part of premedical education, into the medical curriculum appears to be a feasible strategy to improve medical students' understanding of basic science concepts and to increase their motivation and engagement.
Moslehi, Mohsen; Samouei, Rahele; Tayebani, Tayebeh; Kolahduz, Sima
2015-01-01
Considering the increasing importance of emotional intelligence (EI) in different aspects of life, such as academic achievement, the present survey is aimed to predict academic performance of medical students in the comprehensive examination of the basic sciences, according to the indices of emotional intelligence and educational status. The present survey is a descriptive, analytical, and cross-sectional study performed on the medical students of Isfahan, Tehran, and Mashhad Universities of Medical Sciences. Sampling the universities was performed randomly after which selecting the students was done, taking into consideration the limitation in their numbers. Based on the inclusion criteria, all the medical students, entrance of 2005, who had attended the comprehensive basic sciences examination in 2008, entered the study. The data collection tools included an Emotional Intelligence Questionnaire (standardized in Isfahan), the average score of the first to fifth semesters, total average of each of the five semesters, and the grade of the comprehensive basic sciences examination. The data were analyzed through stepwise regression coefficient by SPSS software version 15. The results indicated that the indicators of independence from an emotional intelligence test and average scores of the first and third academic semesters were significant in predicting the students' academic performance in the comprehensive basic sciences examination. According to the obtained results, the average scores of students, especially in the earlier semesters, as well as the indicators of independence and the self-esteem rate of students can influence their success in the comprehensive basic sciences examination.
The First Amendment and the Web: The Internet Porn Panic and Restricting Indecency in Cyberspace.
ERIC Educational Resources Information Center
Mullin, Dorothy Imrich
In the wake of the Communications Decency Act of 1996, discussions have raged both online and in the press about free speech, online pornography, and the protection of children. This paper discusses the legal and social science issues surrounding content regulation of the World Wide Web and the Internet as a whole, with an emphasis on the…
Study of the Unsteady Aerodynamics associated with a Cycloidally Rotating Blade
NASA Astrophysics Data System (ADS)
Agarwal, Nishant
Cycloidal Rotors have been studied for over 100 years, with a focus on applications for vertical axis wind turbines (VAWTs) for energy production and vertical-take-off-and-landing (VTOL) vehicles. Although, numerous experimental and analytical studies have demonstrated their potential competency compared to conventional horizontal-axis rotors, it is not until recently that the focus of these studies has shifted towards understanding the fundamental science behind how these complex systems function. The present study extends the existing fundamental knowledge about cycloidal rotors by particularly focusing on the unsteady aerodynamic phenomena associated with a single-fixed NACA 0012 blade cycloidal rotor as the system translates across an advance ratio (mu = Uinfinity/oR ) of 1. This phenomena was studied both experimentally, making use of particle image velocimetry (PIV) measurements on the system, and computationally, making use of both simple analytical tools and two-dimensional Unsteady Reynolds-Averaged Navier Stokes computational fluid dynamics (URANS-CFD) simulations. It is important to study the transition of the system through mu = 1 in order to better understand the incapability of VAWTs to self-start, and also the progression of VTOL vehicles into forward flight. When the advance ratio is less than one the blade cuts through its own wake. As it approaches one the local airspeed of the flow over the airfoil approaches zero during the retreating portion of the cycle. Finally, as the advance ratio increases beyond one the airfoil will experience reversed flow relative to its direction of rotation. The analysis of the PIV results show that the flow just downstream of the rotor is similar for cases at the same advance ratios, and that the wake structures do not depend upon the Reynolds number, within the range investigated. The phase-history velocity contour plots of the wake structure show a distinct cycloidal pattern for the advance ratio of mu = 1.25, a more stationary wake pattern for mu = 1, and a retarding wake pattern for mu = 0.75. CFD analysis using three different turbulence models showed that an asymmetric wake was generated behind the rotor with a more complex structure (both inside and outside the rotor diameter). This asymmetric wake generation is attributed to the difference in flow conditions at the advancing and retreating sides of the cycle. The complex structures account for the occurrence of dynamic stall, shedding of wake from the trailing edge, flow reversal on the airfoil in the cycle, and the wake-blade interaction. Also, it is observed that a region of high velocity is generated by the airfoil as it sweeps through the flow, which interacts with the airfoil at a later point in the cycle and affects the net force on the airfoil. It was seen that the blade-vortex interaction is not a characteristic property of the cycloidal rotor system. Rather, it depends on the advance ratio at which the system operates.
Welding As Science: Applying Basic Engineering Principles to the Discipline
NASA Technical Reports Server (NTRS)
Nunes, A. C., Jr.
2010-01-01
This Technical Memorandum provides sample problems illustrating ways in which basic engineering science has been applied to the discipline of welding. Perhaps inferences may be drawn regarding optimal approaches to particular welding problems, as well as for the optimal education for welding engineers. Perhaps also some readers may be attracted to the science(s) of welding and may make worthwhile contributions to the discipline.
Ferrer, Rebecca A; Green, Paige A; Barrett, Lisa Feldman
2015-05-01
Cancer control research involves the conduct of basic and applied behavioral and social sciences to reduce cancer incidence, morbidity, and mortality and improve quality of life. Given the importance of behavior in cancer control, fundamental research is necessary to identify psychological mechanisms underlying cancer risk, prevention, and management behaviors. Cancer prevention, diagnosis, and treatment are often emotionally laden. As such, affective science research to elucidate questions related to the basic phenomenological nature of emotion, stress, and mood is necessary to understand how cancer control can be hindered or facilitated by emotional experiences. To date, the intersection of basic affective science research and cancer control remains largely unexplored. The goal of this article is to outline key questions in the cancer control research domain that provide an ecologically valid context for new affective science discoveries. We also provide examples of ways in which basic affective discoveries could inform future cancer prevention and control research. These examples are not meant to be exhaustive or prescriptive but instead are offered to generate creative thought about the promise of a cancer research context for answering basic affective science questions. Together, these examples provide a compelling argument for fostering collaborations between affective and cancer control scientists. © The Author(s) 2015.
High Resolution DNS of Turbulent Flows using an Adaptive, Finite Volume Method
NASA Astrophysics Data System (ADS)
Trebotich, David
2014-11-01
We present a new computational capability for high resolution simulation of incompressible viscous flows. Our approach is based on cut cell methods where an irregular geometry such as a bluff body is intersected with a rectangular Cartesian grid resulting in cut cells near the boundary. In the cut cells we use a conservative discretization based on a discrete form of the divergence theorem to approximate fluxes for elliptic and hyperbolic terms in the Navier-Stokes equations. Away from the boundary the method reduces to a finite difference method. The algorithm is implemented in the Chombo software framework which supports adaptive mesh refinement and massively parallel computations. The code is scalable to 200,000 + processor cores on DOE supercomputers, resulting in DNS studies at unprecedented scale and resolution. For flow past a cylinder in transition (Re = 300) we observe a number of secondary structures in the far wake in 2D where the wake is over 120 cylinder diameters in length. These are compared with the more regularized wake structures in 3D at the same scale. For flow past a sphere (Re = 600) we resolve an arrowhead structure in the velocity in the near wake. The effectiveness of AMR is further highlighted in a simulation of turbulent flow (Re = 6000) in the contraction of an oil well blowout preventer. This material is based upon work supported by the U.S. Department of Energy, Office of Science, Office of Advanced Scientific Computing Research, Applied Mathematics program under Contract Number DE-AC02-05-CH11231.
Scientific Citizenship and good governance: implications for biotechnology.
Davies, Keith G; Wolf-Phillips, Jonathan
2006-02-01
In the wake of public distrust regarding biotechnology, it has been suggested that the debate should be moved "upstream", whereby the public help to set research priorities. Although many scientists see this as an illogical reaction to a loss of faith in science, we argue that the boundaries between science and its technological applications have become blurred and this produces conflicts of interests that have led to this crisis of trust. Furthermore, this distrust is also a crisis in governance that calls for a new open and democratic approach to scientific research. We propose that the concept of Scientific Citizenship, based on good governance, will help to restore public trust and bridge the gap between science and the society that it serves. Integral to this is the suggestion that the governance of science forms part of the training for scientists.
ERIC Educational Resources Information Center
Odili, John Nwanibeze; Ebisine, Sele Sylvester; Ajuar, Helen Nwakaife
2011-01-01
The study investigated teachers' involvement in implementing the basic science and technology curriculum in primary schools in WSLGA (Warri South Local Government Area) of Delta State. It sought to identify the availability of the document in primary schools and teachers' knowledge of the objectives and activities specified in the curriculum.…
Medical Microbiology: Deficits and Remedies
ERIC Educational Resources Information Center
Gabridge, Michael G.
1974-01-01
Microbiology is a typical medical science in which basic information can have direct application. Yet, surveys and questionnaires of recent medical school graduates indicate a serious lack of retentiion in regard to basic biological science. (Author)
Cancer Pharmacogenomics: Integrating Discoveries in Basic, Clinical and Population Sciences to Advance Predictive Cancer Care, a 2010 workshop sponsored by the Epidemiology and Genomics Research Program.
Cognition before curriculum: rethinking the integration of basic science and clinical learning.
Kulasegaram, Kulamakan Mahan; Martimianakis, Maria Athina; Mylopoulos, Maria; Whitehead, Cynthia R; Woods, Nicole N
2013-10-01
Integrating basic science and clinical concepts in the undergraduate medical curriculum is an important challenge for medical education. The health professions education literature includes a variety of educational strategies for integrating basic science and clinical concepts at multiple levels of the curriculum. To date, assessment of this literature has been limited. In this critical narrative review, the authors analyzed literature published in the last 30 years (1982-2012) using a previously published integration framework. They included studies that documented approaches to integration at the level of programs, courses, or teaching sessions and that aimed to improve learning outcomes. The authors evaluated these studies for evidence of successful integration and to identify factors that contribute to integration. Several strategies at the program and course level are well described but poorly evaluated. Multiple factors contribute to successful learning, so identifying how interventions at these levels result in successful integration is difficult. Evidence from session-level interventions and experimental studies suggests that integration can be achieved if learning interventions attempt to link basic and clinical science in a causal relationship. These interventions attend to how learners connect different domains of knowledge and suggest that successful integration requires learners to build cognitive associations between basic and clinical science. One way of understanding the integration of basic and clinical science is as a cognitive activity occurring within learners. This perspective suggests that learner-centered, content-focused, and session-level-oriented strategies can achieve cognitive integration.
Charging of Basic Structural Shapes in a Simulated Lunar Environment
NASA Technical Reports Server (NTRS)
Craven, P.; Schneider, T.; Vaughn, J.; Wang, J.; Polansky, J.
2012-01-01
In order to understand the effect of the charging environment on and around structures on the lunar surface, we have exposed basic structural shapes to electrons and Vacuum Ultra-Violet (VUV) radiation. The objects were, in separate runs, isolated, grounded, and placed on dielectric surfaces. In this presentation, the effects of electron energy, VUV flux, and sample orientation, on the charging of the objects will be examined. The potential of each of the object surfaces was monitored in order to determine the magnitude of the ram and wake effects under different orientations relative to the incoming beams (solar wind). This is a part of, and complementary to, the study of the group at USC under Dr. J. Wang, the purpose of which is to model the effects of the charging environment on structures on the lunar surface.
Improving Learning in Science and Basic Skills among Diverse Student Populations.
ERIC Educational Resources Information Center
Sutman, Francis X.; Guzman, Ana
This monograph is a rich resource of information designed to strengthen science and basic skills teaching, and improve learning for limited English proficient (LEP) minority student populations. It proposes the use of hands-on science investigations as the driving force for mathematics and English language development. The materials included in…
Endoplasmic reticulum stress in wake-active neurons progresses with aging.
Naidoo, Nirinjini; Zhu, Jingxu; Zhu, Yan; Fenik, Polina; Lian, Jie; Galante, Ray; Veasey, Sigrid
2011-08-01
Fragmentation of wakefulness and sleep are expected outcomes of advanced aging. We hypothesize that wake neurons develop endoplasmic reticulum dyshomeostasis with aging, in parallel with impaired wakefulness. In this series of experiments, we sought to more fully characterize age-related changes in wakefulness and then, in relevant wake neuronal populations, explore functionality and endoplasmic reticulum homeostasis. We report that old mice show greater sleep/wake transitions in the active period with markedly shortened wake periods, shortened latencies to sleep, and less wake time in the subjective day in response to a novel social encounter. Consistent with sleep/wake instability and reduced social encounter wakefulness, orexinergic and noradrenergic wake neurons in aged mice show reduced c-fos response to wakefulness and endoplasmic reticulum dyshomeostasis with increased nuclear translocation of CHOP and GADD34. We have identified an age-related unfolded protein response injury to and dysfunction of wake neurons. It is anticipated that these changes contribute to sleep/wake fragmentation and cognitive impairment in aging. © 2011 The Authors. Aging Cell © 2011 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland.
ERIC Educational Resources Information Center
Subali, Bambang; Paidi; Mariyam, Siti
2016-01-01
This research aims at measuring the divergent thinking of basic skills of science process skills (SPS) of life aspects in Natural Sciences subjects on Elementary School. The test instruments used in this research have been standardized through the development of instruments. In this case, the tests were tried out to 3070 students. The results of…
Reinventing Biostatistics Education for Basic Scientists
Weissgerber, Tracey L.; Garovic, Vesna D.; Milin-Lazovic, Jelena S.; Winham, Stacey J.; Obradovic, Zoran; Trzeciakowski, Jerome P.; Milic, Natasa M.
2016-01-01
Numerous studies demonstrating that statistical errors are common in basic science publications have led to calls to improve statistical training for basic scientists. In this article, we sought to evaluate statistical requirements for PhD training and to identify opportunities for improving biostatistics education in the basic sciences. We provide recommendations for improving statistics training for basic biomedical scientists, including: 1. Encouraging departments to require statistics training, 2. Tailoring coursework to the students’ fields of research, and 3. Developing tools and strategies to promote education and dissemination of statistical knowledge. We also provide a list of statistical considerations that should be addressed in statistics education for basic scientists. PMID:27058055
Exhibits and More: How Scientists Can Partner with Aquariums and Science Centers
NASA Astrophysics Data System (ADS)
Spitzer, B.
2004-12-01
Informal science institutions include science museums, aquariums, zoos, nature centers and other institutions that offer the public opportunities for free-choice, voluntary, and self-directed learning. Less than 20% of our lives is spent in formal schooling, and even among schoolchildren only 20% of their waking hours are spent in the classroom. Informal science institutions can have a significant impact on what the public knows, believes, and cares about. These institutions reach very large audiences, and are considered trusted information sources by the general public. Informal science institutions offer a wide range of learning opportunities including exhibits, films, professional development for teachers, educational programs for children and adults, field trips, publications, websites, and more. Many informal learning centers are experienced in working with scientists as content experts, welcome their participation, make efficient use of their time, and are skilled at translating science for the general public. Several case studies will illustrate successful models for scientists engaging in development of exhibits, films, programs, and educational materials.
Translating orthopaedic basic science into clinical relevance.
Madry, Henning
2014-12-01
In orthopaedic and trauma surgery, the rapid evolution of biomedical research has fundamentally changed the perception of the musculoskeletal system. Here, the rigor of basic science and the art of musculoskeletal surgery have come together to create a new discipline -experimental orthopaedics- that holds great promise for the causative cure of many orthopaedic conditions. The Journal of Experimental Orthopaedics intends to bridge the gap between orthopaedic basic science and clinical relevance, to allow for a fruitful clinical translation of excellent and important investigations in the field of the entire musculoskeletal system.
Approaches to Measuring the Effects of Wake-Promoting Drugs: A Focus on Cognitive Function
Edgar, Christopher J.; Pace-Schott, Edward F.; Wesnes, Keith A.
2009-01-01
Objectives In clinical drug development, wakefulness and wake-promotion maybe assessed by a large number of scales and questionnaires. Objective assessment of wakefulness is most commonly made using sleep latency/maintenance of wakefulness tests, polysomnography and/or behavioral measures. The purpose of the present review is to highlight the degree of overlap in the assessment of wakefulness and cognition, with consideration of assessment techniques and the underlying neurobiology of both concepts. Design Reviews of four key areas were conducted: commonly used techniques in the assessment of wakefulness; neurobiology of sleep/wake and cognition; targets of wake promoting and/or cognition enhancing drugs; and ongoing clinical trials investigating wake promoting effects. Results There is clear overlap between the assessment of wakefulness and cognition. There are common techniques which may be used to assess both concepts; aspects of the neurobiology of both concepts may be closely related; and wake promoting drugs may have nootropic properties (and vice-versa). Clinical trials of wake promoting drugs often, though not routinely, assess aspects of cognition. Conclusions Routine and broad assessment of cognition in the development of wake promoting drugs may reveal important nootropic effects, which are not secondary to alertness/wakefulness, whilst existing cognitive enhancers may have under explored or unknown wake promoting properties. PMID:19565524
Dynamic wake prediction and visualization with uncertainty analysis
NASA Technical Reports Server (NTRS)
Holforty, Wendy L. (Inventor); Powell, J. David (Inventor)
2005-01-01
A dynamic wake avoidance system utilizes aircraft and atmospheric parameters readily available in flight to model and predict airborne wake vortices in real time. A novel combination of algorithms allows for a relatively simple yet robust wake model to be constructed based on information extracted from a broadcast. The system predicts the location and movement of the wake based on the nominal wake model and correspondingly performs an uncertainty analysis on the wake model to determine a wake hazard zone (no fly zone), which comprises a plurality of wake planes, each moving independently from another. The system selectively adjusts dimensions of each wake plane to minimize spatial and temporal uncertainty, thereby ensuring that the actual wake is within the wake hazard zone. The predicted wake hazard zone is communicated in real time directly to a user via a realistic visual representation. In an example, the wake hazard zone is visualized on a 3-D flight deck display to enable a pilot to visualize or see a neighboring aircraft as well as its wake. The system substantially enhances the pilot's situational awareness and allows for a further safe decrease in spacing, which could alleviate airport and airspace congestion.
WAKE ISLAND AIRFIELD TERMINAL, BUILDING 1502 LOOKING EAST WITH PHOTO ...
WAKE ISLAND AIRFIELD TERMINAL, BUILDING 1502 LOOKING EAST WITH PHOTO SCALE CENTERED ON BUILDING (12/30/2008) - Wake Island Airfield, Terminal Building, West Side of Wake Avenue, Wake Island, Wake Island, UM
Moslehi, Mohsen; Samouei, Rahele; Tayebani, Tayebeh; Kolahduz, Sima
2015-01-01
Background: Considering the increasing importance of emotional intelligence (EI) in different aspects of life, such as academic achievement, the present survey is aimed to predict academic performance of medical students in the comprehensive examination of the basic sciences, according to the indices of emotional intelligence and educational status. Materials and Methods: The present survey is a descriptive, analytical, and cross-sectional study performed on the medical students of Isfahan, Tehran, and Mashhad Universities of Medical Sciences. Sampling the universities was performed randomly after which selecting the students was done, taking into consideration the limitation in their numbers. Based on the inclusion criteria, all the medical students, entrance of 2005, who had attended the comprehensive basic sciences examination in 2008, entered the study. The data collection tools included an Emotional Intelligence Questionnaire (standardized in Isfahan), the average score of the first to fifth semesters, total average of each of the five semesters, and the grade of the comprehensive basic sciences examination. The data were analyzed through stepwise regression coefficient by SPSS software version 15. Results: The results indicated that the indicators of independence from an emotional intelligence test and average scores of the first and third academic semesters were significant in predicting the students’ academic performance in the comprehensive basic sciences examination. Conclusion: According to the obtained results, the average scores of students, especially in the earlier semesters, as well as the indicators of independence and the self-esteem rate of students can influence their success in the comprehensive basic sciences examination. PMID:26430693
Contexts, concepts and cognition: principles for the transfer of basic science knowledge.
Kulasegaram, Kulamakan M; Chaudhary, Zarah; Woods, Nicole; Dore, Kelly; Neville, Alan; Norman, Geoffrey
2017-02-01
Transfer of basic science aids novices in the development of clinical reasoning. The literature suggests that although transfer is often difficult for novices, it can be optimised by two complementary strategies: (i) focusing learners on conceptual knowledge of basic science or (ii) exposing learners to multiple contexts in which the basic science concepts may apply. The relative efficacy of each strategy as well as the mechanisms that facilitate transfer are unknown. In two sequential experiments, we compared both strategies and explored mechanistic changes in how learners address new transfer problems. Experiment 1 was a 2 × 3 design in which participants were randomised to learn three physiology concepts with or without emphasis on the conceptual structure of basic science via illustrative analogies and by means of one, two or three contexts during practice (operationalised as organ systems). Transfer of these concepts to explain pathologies in familiar organ systems (near transfer) and unfamiliar organ systems (far transfer) was evaluated during immediate and delayed testing. Experiment 2 examined whether exposure to conceptual analogies and multiple contexts changed how learners classified new problems. Experiment 1 showed that increasing context variation significantly improved far transfer performance but there was no difference between two and three contexts during practice. Similarly, the increased conceptual analogies led to higher performance for far transfer. Both interventions had independent but additive effects on overall performance. Experiment 2 showed that such analogies and context variation caused learners to shift to using structural characteristics to classify new problems even when there was superficial similarity to previous examples. Understanding problems based on conceptual structural characteristics is necessary for successful transfer. Transfer of basic science can be optimised by using multiple strategies that collectively emphasise conceptual structure. This means teaching must focus on conserved basic science knowledge and de-emphasise superficial features. © 2017 John Wiley & Sons Ltd and The Association for the Study of Medical Education.
Spedding, G R; Hedenström, A H; McArthur, J; Rosén, M
2008-01-01
Bird flight occurs over a range of Reynolds numbers (Re; 10(4) < or = Re < or = 10(5), where Re is a measure of the relative importance of inertia and viscosity) that includes regimes where standard aerofoil performance is difficult to predict, compute or measure, with large performance jumps in response to small changes in geometry or environmental conditions. A comparison of measurements of fixed wing performance as a function of Re, combined with quantitative flow visualisation techniques, shows that, surprisingly, wakes of flapping bird wings at moderate flight speeds admit to certain simplifications where their basic properties can be understood through quasi-steady analysis. Indeed, a commonly cited measure of the relative flapping frequency, or wake unsteadiness, the Strouhal number, is seen to be approximately constant in accordance with a simple requirement for maintaining a moderate local angle of attack on the wing. Together, the measurements imply a fine control of boundary layer separation on the wings, with implications for control strategies and wing shape selection by natural and artificial fliers.
Simplified Aircraft-Based Paired Approach: Concept Definition and Initial Analysis
NASA Technical Reports Server (NTRS)
Johnson, Sally C.; Lohr, Gary W.; McKissick, Burnell T.; Abbott, Terence S.; Geurreiro, Nelson M.; Volk, Paul
2013-01-01
Simplified Aircraft-based Parallel Approach (SAPA) is an advanced concept proposed by the Federal Aviation Administration (FAA) to support dependent parallel approach operations to runways with lateral spacing closer than 2500 ft. At the request of the FAA, NASA performed an initial assessment of the potential performance and feasibility of the SAPA concept, including developing and assessing an operational implementation of the concept and conducting a Monte Carlo wake simulation study to examine the longitudinal spacing requirements. The SAPA concept was shown to have significant operational advantages in supporting the pairing of aircraft with dissimilar final approach speeds. The wake simulation study showed that support for dissimilar final approach speeds could be significantly enhanced through the use of a two-phased altitudebased longitudinal positioning requirement, with larger longitudinal positioning allowed for higher altitudes out of ground effect and tighter longitudinal positioning defined for altitudes near and in ground effect. While this assessment is preliminary and there are a number of operational issues still to be examined, it has shown the basic SAPA concept to be technically and operationally feasible.
The Basic Science Curriculum in the 21st Century: What Needs to Be Changed?
ERIC Educational Resources Information Center
Garant, Philias R.
1986-01-01
The basic science curriculum in dental education could be improved by adopting a curriculum containing only two integrated required science courses about (1) the structure and function of the human body and (2) disease and reaction to disease in the human body. Elective graduate-level predoctoral courses would allow specialization. (MSE)
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-01
... actively involved in both basic and applied research in coastal waters of the northern Gulf of Mexico. The... between the Center for Food Safety and Applied Nutrition (CFSAN) and the Marine Environmental Sciences Consortium/Dauphin Island Sea Lab (DISL). The goal of the DISL is marine science education, basic and applied...
Development and Validation of a Project Package for Junior Secondary School Basic Science
ERIC Educational Resources Information Center
Udofia, Nsikak-Abasi
2014-01-01
This was a Research and Developmental study designed to develop and validate projects for Junior Secondary School Basic Science instruction and evaluation. The projects were developed using the project blueprint and sent for validation by experts in science education and measurement and evaluation; using a project validation scale. They were to…
How do scientists respond to anomalies? Different strategies used in basic and applied science.
Trickett, Susan Bell; Trafton, J Gregory; Schunn, Christian D
2009-10-01
We conducted two in vivo studies to explore how scientists respond to anomalies. Based on prior research, we identify three candidate strategies: mental simulation, mental manipulation of an image, and comparison between images. In Study 1, we compared experts in basic and applied domains (physics and meteorology). We found that the basic scientists used mental simulation to resolve an anomaly, whereas applied science practitioners mentally manipulated the image. In Study 2, we compared novice and expert meteorologists. We found that unlike experts, novices used comparison to address anomalies. We discuss the nature of expertise in the two kinds of science, the relationship between the type of science and the task performed, and the relationship of the strategies investigated to scientific creativity. Copyright © 2009 Cognitive Science Society, Inc.
Bode, Michael F; Hilgendorf, Ingo
2018-06-09
Political bodies and professional societies acknowledge that translational research benefits from researchers trained in both, clinical medicine and basic science. Yet, few physicians undergoing clinical training in cardiology seek this dual career (Milewicz et al. J Clin Invest 125:3742-3747, 2015). The reasons are likely manifold, but with cardiology having become increasingly interventional and facing economic pressure, how much attention, credit, and encouragement is given to physicians interested in basic cardiovascular science? Having studied and worked in hospitals and laboratories, in both Germany and the USA, we aim to compare in this article how basic science education is currently integrated into cardiology training at German and US university hospitals, from medical school to more advanced career stages. By doing so, we hope to provide some outside perspectives to young physicians and decision makers alike, that may inspire changes to curricula in the respective countries and around the world.
Three-dimensional structure of wind turbine wakes as measured by scanning lidar
NASA Astrophysics Data System (ADS)
Bodini, Nicola; Zardi, Dino; Lundquist, Julie K.
2017-08-01
The lower wind speeds and increased turbulence that are characteristic of turbine wakes have considerable consequences on large wind farms: turbines located downwind generate less power and experience increased turbulent loads. The structures of wakes and their downwind impacts are sensitive to wind speed and atmospheric variability. Wake characterization can provide important insights for turbine layout optimization in view of decreasing the cost of wind energy. The CWEX-13 field campaign, which took place between June and September 2013 in a wind farm in Iowa, was designed to explore the interaction of multiple wakes in a range of atmospheric stability conditions. Based on lidar wind measurements, we extend, present, and apply a quantitative algorithm to assess wake parameters such as the velocity deficits, the size of the wake boundaries, and the location of the wake centerlines. We focus on wakes from a row of four turbines at the leading edge of the wind farm to explore variations between wakes from the edge of the row (outer wakes) and those from turbines in the center of the row (inner wakes). Using multiple horizontal scans at different elevations, a three-dimensional structure of wakes from the row of turbines can be created. Wakes erode very quickly during unstable conditions and can in fact be detected primarily in stable conditions in the conditions measured here. During stable conditions, important differences emerge between the wakes of inner turbines and the wakes of outer turbines. Further, the strong wind veer associated with stable conditions results in a stretching of the wake structures, and this stretching manifests differently for inner and outer wakes. These insights can be incorporated into low-order wake models for wind farm layout optimization or for wind power forecasting.
Three-dimensional structure of wind turbine wakes as measured by scanning lidar
Bodini, Nicola; Zardi, Dino; Lundquist, Julie K.
2017-08-14
The lower wind speeds and increased turbulence that are characteristic of turbine wakes have considerable consequences on large wind farms: turbines located downwind generate less power and experience increased turbulent loads. The structures of wakes and their downwind impacts are sensitive to wind speed and atmospheric variability. Wake characterization can provide important insights for turbine layout optimization in view of decreasing the cost of wind energy. The CWEX-13 field campaign, which took place between June and September 2013 in a wind farm in Iowa, was designed to explore the interaction of multiple wakes in a range of atmospheric stability conditions.more » Based on lidar wind measurements, we extend, present, and apply a quantitative algorithm to assess wake parameters such as the velocity deficits, the size of the wake boundaries, and the location of the wake centerlines. We focus on wakes from a row of four turbines at the leading edge of the wind farm to explore variations between wakes from the edge of the row (outer wakes) and those from turbines in the center of the row (inner wakes). Using multiple horizontal scans at different elevations, a three-dimensional structure of wakes from the row of turbines can be created. Wakes erode very quickly during unstable conditions and can in fact be detected primarily in stable conditions in the conditions measured here. During stable conditions, important differences emerge between the wakes of inner turbines and the wakes of outer turbines. Further, the strong wind veer associated with stable conditions results in a stretching of the wake structures, and this stretching manifests differently for inner and outer wakes. As a result, these insights can be incorporated into low-order wake models for wind farm layout optimization or for wind power forecasting.« less
Three-dimensional structure of wind turbine wakes as measured by scanning lidar
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bodini, Nicola; Zardi, Dino; Lundquist, Julie K.
The lower wind speeds and increased turbulence that are characteristic of turbine wakes have considerable consequences on large wind farms: turbines located downwind generate less power and experience increased turbulent loads. The structures of wakes and their downwind impacts are sensitive to wind speed and atmospheric variability. Wake characterization can provide important insights for turbine layout optimization in view of decreasing the cost of wind energy. The CWEX-13 field campaign, which took place between June and September 2013 in a wind farm in Iowa, was designed to explore the interaction of multiple wakes in a range of atmospheric stability conditions.more » Based on lidar wind measurements, we extend, present, and apply a quantitative algorithm to assess wake parameters such as the velocity deficits, the size of the wake boundaries, and the location of the wake centerlines. We focus on wakes from a row of four turbines at the leading edge of the wind farm to explore variations between wakes from the edge of the row (outer wakes) and those from turbines in the center of the row (inner wakes). Using multiple horizontal scans at different elevations, a three-dimensional structure of wakes from the row of turbines can be created. Wakes erode very quickly during unstable conditions and can in fact be detected primarily in stable conditions in the conditions measured here. During stable conditions, important differences emerge between the wakes of inner turbines and the wakes of outer turbines. Further, the strong wind veer associated with stable conditions results in a stretching of the wake structures, and this stretching manifests differently for inner and outer wakes. As a result, these insights can be incorporated into low-order wake models for wind farm layout optimization or for wind power forecasting.« less
NASA Technical Reports Server (NTRS)
Stacey, J. M.
1991-01-01
Monograph presents comprehensive overview of science and technology of spaceborne microwave-imaging systems. Microwave images used as versatile orbiting, remote-sensing systems to investigate atmospheres and surfaces of planets. Detect surface objects through canopies of clouds, measure distributions of raindrops in clouds that their views penetrate, find meandering rivers in rain forests and underground water in arid regions, and provide information on ocean currents, wakes, ice/water boundaries, aircraft, ships, buoys, and bridges.
Karl Malcolm; Chuck Rhoades; Michael Battaglia; Paula Fornwalt; Rob Hubbard; Kelly Elder; Byron Collins
2012-01-01
Changing climatic conditions and an abundance of dense, mature pine forests have helped to spur an epidemic of mountain pine beetles larger than any in recorded history. Millions of forested acres have been heavily impacted and have experienced extreme rates of tree mortality. This has raised concerns among many people that the death, desiccation, and decomposition of...
Vortex wakes of a flapping foil in a flowing soap film
NASA Astrophysics Data System (ADS)
Schnipper, Teis; Andersen, Anders; Bohr, Tomas
2008-11-01
We present an experimental study of an oscillating, symmetric foil in a vertically flowing soap film. By varying frequency and amplitude of the oscillation we explore and visualize a variety of wake structures, including von Kármán wake, reverse von Kármán wake, 2P wake, and 2P+2S wake. We characterize the transition from the von Kármán wake (drag) to the reverse von Kármán wake (thrust) and discuss the results in relation to fish swimming. We visualize the time evolution of the vortex shedding in detail, identify the origins of the vortices comprising the wake, and propose a simple model to account for the transition from von Kármán like wakes to more exotic wake structures.
Eisenstein, Anna; Vaisman, Lev; Johnston-Cox, Hillary; Gallan, Alexander; Shaffer, Kitt; Vaughan, Deborah; O'Hara, Carl; Joseph, Lija
2014-01-01
Curricular integration has emerged as a consistent theme in medical education reform. Vertical integration of topics such as pathology offers the potential to bring basic science content into the clinical arena, but faculty/student acceptance and curricular design pose challenges for such integration. The authors describe the Cadaver Biopsy Project (CBP) at Boston University School of Medicine as a sustainable model of vertical integration. Faculty and select senior medical students obtained biopsies of cadavers during the first-year gross anatomy course (fall 2009) and used these to develop clinical cases for courses in histology (spring 2010), pathology (fall 2010-spring 2011), and radiology (fall 2011 or spring 2012), thereby linking students' first experiences in basic sciences with other basic science courses and later clinical courses. Project goals included engaging medical stu dents in applying basic science princi ples in all aspects of patient care as they acquire skills. The educational intervention used a patient (cadaver)-centered approach and small-group, collaborative, case-based learning. Through this project, the authors involved clinical and basic science faculty-plus senior medical students-in a collaborative project to design and implement an integrated curriculum through which students revisited, at several different points, the microscopic structure and pathophysiology of common diseases. Developing appropriate, measurable out comes for medical education initiatives, including the CBP, is challenging. Accumu lation of qualitative feedback from surveys will guide continuous improvement of the CBP. Documenting longer-term impact of the curricular innovation on test scores and other competency-based outcomes is an ultimate goal.
Comparison of traditional six-year and new four-year dental curricula in South Korea.
Komabayashi, Takashi; Ahn, Chul; Kim, Kang-Ju; Oh, Hyo-Won
2012-01-01
This study aimed to compare the dental curriculum of the traditional six-year system with that of the new four-year (graduate-entry) system in South Korea. There are 11 dental schools in South Korea: six are public and five are private. Eight offer the new four-year program and the other three offer the traditional six-year program. Descriptive analyses were conducted using bibliographic data and local information along with statistical analyses such as chi-square tests. In the six-year programs, clinical dentistry subjects were taught almost equally in practical and didactic courses, while the basic science courses were taught more often as practical courses (P < 0.0001). In the four-year programs, both the basic science and clinical dentistry subjects were taught didactically more often; while more dentistry subjects were taught than basic sciences (P = 0.004). The four-year program model in South Korea is more focused on dentistry than on basic science, while both basic and clinical dentistry subjects were equally taught in the six-year program.
Evaluation of Fast-Time Wake Vortex Models using Wake Encounter Flight Test Data
NASA Technical Reports Server (NTRS)
Ahmad, Nashat N.; VanValkenburg, Randal L.; Bowles, Roland L.; Limon Duparcmeur, Fanny M.; Gloudesman, Thijs; van Lochem, Sander; Ras, Eelco
2014-01-01
This paper describes a methodology for the integration and evaluation of fast-time wake models with flight data. The National Aeronautics and Space Administration conducted detailed flight tests in 1995 and 1997 under the Aircraft Vortex Spacing System Program to characterize wake vortex decay and wake encounter dynamics. In this study, data collected during Flight 705 were used to evaluate NASA's fast-time wake transport and decay models. Deterministic and Monte-Carlo simulations were conducted to define wake hazard bounds behind the wake generator. The methodology described in this paper can be used for further validation of fast-time wake models using en-route flight data, and for determining wake turbulence constraints in the design of air traffic management concepts.
NASA Astrophysics Data System (ADS)
Ben-Zvi-Assaraf, Orit; Even-Israel, Chava
2011-08-01
The "Medical Systems" program was designed to introduce high school students to the world of advanced medicine. Its premise was to use an applied scientific discipline like medicine to encourage high-school students' interest in basic science. This study compares the teen-aged graduates of "Medical Systems" with fourth and fifth-year medical students. It aims to identify the attitudes of these two groups towards medical science and basic sciences in medicine. The population included 94 graduates of "Medical Systems" from schools throughout Israel, who had also completed an advanced-level course in a basic science (biology, chemistry or physics), and 96 medical students from different Israeli universities. The students' attitudes were measured using West et al.'s questionnaire (Med Educ 16(4):188-191, 1982), which assesses both the attitude of the participants towards basic science knowledge, and their attitude towards their learning experience in medical school. Nine participants from each group were also interviewed using a semi-structured interview protocol. The results showed essential differences in the attitudes of the two groups. The high school students consider scientific knowledge far more essential for a physician than do the medical students, who also showed a far lower estimation of the effectiveness of their science studies.
ERIC Educational Resources Information Center
National Council on Teacher Quality, 2010
2010-01-01
The basic story line of the STEM (Science, Technology, Engineering and Mathematics) crisis is, at this point, well known. In an increasingly interdependent and technology-driven economy, America is falling behind. A substantial number of students cannot perform basic math. U.S. students lag behind peers in international comparisons of science…
United Nations/European Space Agency Workshops on Basic Space Science
NASA Technical Reports Server (NTRS)
Haubold, H. J.; Ocampo, A.; Torres, S.; Wamsteker, W.
1995-01-01
In 1958, the United Nations (UN) formally recognized a new potential for international cooperation by establishing an ad hoc Committee on the Peaceful Uses of Outer Space (COPUOS). A year later the Committee became a permanent body, and by 1983 membership had expanded to 53 states, with more than half of the members coming from the developing world. In 1970, COPUOS established the UN Program on Space Applications in order to strengthen cooperation in space science and technology between non-industrialized and industrialized countries. In the last few years, the UN and its COPUOS have paid increasing attention to education and research in space science and technology, including basic space science. In 1991 the UN, in cooperation with ESA, initiated the organization of annual Workshops in Basic Space Science for developing countries. These Workshops are designed to be held in one of the following major regions: Asia and the Pacific, Latin America and the Caribbean, Africa, Western Asia, and Europe. Accordingly, Basic Space Science Workshops have already been held in India (1991), Costa Rica andColombia (1992), and Nigeria (1993). The fourth Workshop was held from 27 June to 1 July 1994 at the Cairo University, in Egypt, for Western Asia.
[Basic science and applied science].
Pérez-Tamayo, R
2001-01-01
A lecture was presented by the author at the Democratic Opinion Forum on Health Teaching and Research, organized by Mexico's National Health Institutes Coordinating Office, at National Cardiology Institute "Ignacio Chavez", where he presented a critical review of the conventional classification of basic and applied science, as well as his personal view on health science teaching and research. According to the author, "well-conducted science" is that "generating reality-checked knowledge" and "mis-conducted science" is that "unproductive or producing 'just lies' and 'non-fundable'. To support his views, the author reviews utilitarian and pejorative definitions of science, as well as those of committed and pure science, useful and useless science, and practical and esoterical science, as synonyms of applied and basic science. He also asserts that, in Mexico, "this classification has been used in the past to justify federal funding cutbacks to basic science, allegedly because it is not targeted at solving 'national problems' or because it was not relevant to priorities set in a given six-year political administration period". Regarding health education and research, the author asserts that the current academic programs are inefficient and ineffective; his proposal to tackle these problems is to carry out a solid scientific study, conducted by a multidisciplinary team of experts, "to design the scientific researcher curricula from recruitment of intelligent young people to retirement or death". Performance assessment of researchers would not be restricted to publication of papers, since "the quality of scientific work and contribution to the development of science is not reflected by the number of published papers". The English version of this paper is available at: http://www.insp.mx/salud/index.html
ERIC Educational Resources Information Center
Salameh, Ibrahim Abdul Ghani; Khawaldeh, Mohammad Falah Ali
2014-01-01
The Study aimed at identifying the trends of the students of basic sciences College in the World Islamic Sciences and Education University towards teaching health and sport course by using computer technology as a teaching method, and to identify also the impact of the variables of academic level and the gender on the students' trends. The study…
NASA Astrophysics Data System (ADS)
Haven, Emmanuel; Khrennikov, Andrei
2013-01-01
Preface; Part I. Physics Concepts in Social Science? A Discussion: 1. Classical, statistical and quantum mechanics: all in one; 2. Econophysics: statistical physics and social science; 3. Quantum social science: a non-mathematical motivation; Part II. Mathematics and Physics Preliminaries: 4. Vector calculus and other mathematical preliminaries; 5. Basic elements of quantum mechanics; 6. Basic elements of Bohmian mechanics; Part III. Quantum Probabilistic Effects in Psychology: Basic Questions and Answers: 7. A brief overview; 8. Interference effects in psychology - an introduction; 9. A quantum-like model of decision making; Part IV. Other Quantum Probabilistic Effects in Economics, Finance and Brain Sciences: 10. Financial/economic theory in crisis; 11. Bohmian mechanics in finance and economics; 12. The Bohm-Vigier Model and path simulation; 13. Other applications to economic/financial theory; 14. The neurophysiological sources of quantum-like processing in the brain; Conclusion; Glossary; Index.
Dubois, Eline Agnès; Franson, Kari Lanette
2009-09-01
Basic sciences can be integrated into the medical school curriculum via e-learning. The process of integrating a basic science in this manner resembles a curricular change. The change usually begins with an idea for using e-learning to teach a basic science and establishing the need for the innovation. In the planning phase, learning outcomes are formulated and a prototype of the program is developed based on the desired requirements. A realistic concept is formed after considering the limitations of the current institute. Next, a project team is assembled to develop the program and plan its integration. Incorporation of the e-learning program is facilitated by a well-developed and communicated integration plan. Various course coordinators are contacted to determine content of the e-learning program as well as establish assessment. Linking the e-learning program to existing course activities and thereby applying the basic science into the clinical context enhances the degree of integration. The success of the integration is demonstrated by a positive assessment of the program including favourable cost-benefit analysis and improved student performance. Lastly, when the program becomes institutionalised, continuously updating content and technology (when appropriate), and evaluating the integration contribute to the prolonged survival of the e-learning program.
Tektite 1, man-in-the-sea project: Marine Science Program
Clifton, H.E.; Mahnken, C.V.W.; Van Derwalker, J. C.; Waller, R.A.
1970-01-01
The Tektite experiment was designed to provide data for a number of behavioral, biomedical, and engineering studies in addition to the marine sciences program. Conditions for some of these studies were not altogether compatible with the program for the marine sciences. For example, isolation imposed by human behavioral studies precluded physical contact with the surface team, even though such contact was physically possible and desirable for the conduct of the marine sciences program. Isolation also imposed on the scientific team the duty of all in-habitat maintenance, both scheduled and unscheduled, thereby taking substantial time from scientific research. In addition, between 10 and 20 percent of the waking time was devoted to performance of psychological tests required for the biomedical studies. Most of the experiments were directed toward detecting potentially adverse changes and thus were accepted as necessary and desirable. The only health problem to affect the scientific program during the dive was a minor external ear infection contracted by all the divers. Nonetheless, the experiment demon. strated, at least to our satisfaction, the advantages of underwater habitation and saturation diving for biological and geological research. A major advantage is the opportunity for continuous monitoring of organisms or processes. In addition, underwater habitation provides for considerably more research time in the water than surface diving or intermittent bottom dwelling, and this advantage increases greatly as the depth of habitation increases. Even in the relatively shallow depths at which Tektite 1 was conducted, the undersea team could spend appreciably more time at work in the water than their colleagues on the surface. Finally, Tektite 1 demonstrated that the scientist who lives in the sea need not have the extensive qualifications of a professional diver. Of the four scientists of the in-habitat team, only Crew Chief Waller was so qualified; the other three had used scuba as a research tool, but on a relatively limited basis. Any healthy, well-conditioned marine scientist with a basic diving background is capable of extending his research into the shallow sea on a full-time basis. It is hoped that many such scientists will in the future be able to utilize the undersea laboratory.
NASA Astrophysics Data System (ADS)
Hahm, Y.; Yoon, H.
2016-12-01
Retail location is one of the most critical factors explaining the success of store operations. Store owners prefer to choose locations with high visibility and convenient transportation, which might be likely reasons for higher pedestrian volume, hence larger chance to capture impulse shoppers, resulting in more profits. While researches have focused on discerning relationship between pedestrian route choice and physical environments via indirect measures such as survey questionnaire and interviews, recent technologies such as Global Positioning System (GPS) enables collecting direct and precise waking route data. In this study, we investigate the physical environments in which pedestrians prefer to be in commercial district, and further analyze if such locations encompass stores with higher store revenues. The primary method is GPS experiment and travel diary for over hundred visitors of the study site, Hongik University commercial areas in Seoul, South Korea, and statistical analysis, Structural Equation Model (SEM). With SEM, we could assess endogenous latent variables indicating built environments, such as Density, Diversity, Destination Accessibility, Design, and Retail Attraction, and exogenous latent variable, the pedestrian walking choice, based on the observation of pedestrian volume and walking speed. Observed variables include the number of stores, building uses, kind of retail, and pedestrian volume, and walking speed. This research will shed light on planning commercial districts, emphasizing the role of pedestrian walking in the success of retail business, and providing a clue on how to encourage pedestrian visitation by improving physical environment. This work is supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (No. 2015R1C1A2A01055615)
NASA Astrophysics Data System (ADS)
Nishino, Masaki N.; Harada, Yuki; Saito, Yoshifumi; Tsunakawa, Hideo; Takahashi, Futoshi; Yokota, Shoichiro; Matsushima, Masaki; Shibuya, Hidetoshi; Shimizu, Hisayoshi
2017-09-01
There forms a tenuous region called the wake behind the Moon in the solar wind, and plasma entry/refilling into the wake is a fundamental problem of the lunar plasma science. High-energy ions and electrons in the foreshock of the Earth's magnetosphere were detected at the lunar surface in the Apollo era, but their effects on the lunar night-side environment have never been studied. Here we show the first observation of bow-shock reflected protons by Kaguya (SELENE) spacecraft in orbit around the Moon, confirming that solar wind plasma reflected at the terrestrial bow shock can easily access the deepest lunar wake when the Moon stays in the foreshock (We name this mechanism 'type-3 entry'). In a continuous type-3 event, low-energy electron beams from the lunar night-side surface are not obvious even though the spacecraft location is magnetically connected to the lunar surface. On the other hand, in an intermittent type-3 entry event, the kinetic energy of upward-going field-aligned electron beams decreases from ∼ 80 eV to ∼ 20 eV or electron beams disappear as the bow-shock reflected ions come accompanied by enhanced downward electrons. According to theoretical treatment based on electric current balance at the lunar surface including secondary electron emission by incident electron and ion impact, we deduce that incident ions would be accompanied by a few to several times higher flux of an incident electron flux, which well fits observed downward fluxes. We conclude that impact by the bow-shock reflected ions and electrons raises the electrostatic potential of the lunar night-side surface.
The Case of the Neutron Star With a Wayward Wake
NASA Astrophysics Data System (ADS)
2006-06-01
A long observation with NASA's Chandra X-ray Observatory has revealed important new details of a neutron star that is spewing out a wake of high-energy particles as it races through space. The deduced location of the neutron star on the edge of a supernova remnant, and the peculiar orientation of the neutron star wake, pose mysteries that remain unresolved. "Like a kite flying in the wind, the behavior of this neutron star and its wake tell us what sort of gas it must be plowing through," said Bryan Gaensler of the Harvard-Smithsonian Center for Astrophysics (CfA) in Cambridge, Mass., and lead author of a paper accepted to The Astrophysical Journal. "Yet we're still not sure how the neutron star got to its present location." Animation: Sequence of images of J0617 in IC 443 Animation: Sequence of images of J0617 in IC 443 The neutron star, known as CXOU J061705.3+222127, or J0617 for short, appears to lie near the outer edge of an expanding bubble of hot gas associated with the supernova remnant IC 443. Presumably, J0617 was created at the time of the supernova -- approximately 30,000 years ago -- and propelled away from the site of the explosion at about 500,000 miles per hour. However, the neutron star's wake is oriented almost perpendicularly to the direction expected if the neutron star were moving away from the center of the supernova remnant. This apparent misalignment had previously raised doubts about the association of the speeding neutron star with the supernova remnant. Gaensler and his colleagues provide strong evidence that J0617 was indeed born in the same explosion that created the supernova remnant. First, the shape of the neutron star's wake indicates it is moving a little faster than the speed of sound in Composite Images of SNR IC 443 Composite Images of SNR IC 443 the remnant's multimillion-degree gas. The velocity that one can then calculate from this conclusion closely matches the predicted pace of the neutron star. In contrast, if the neutron star were outside the confines of the remnant, its inferred speed would be a sluggish 20,000 miles per hour. Also, the measured temperature of the neutron star matches that of one born at the same time of the supernova remnant. What then, could cause the misaligned, or wayward, neutron star wake? The authors speculate that perhaps the doomed progenitor star was moving at a high speed before it exploded, so that the explosion site was not at the observed center of the supernova remnant. Fast moving gusts of gas inside the supernova remnant have further pushed the neutron star's wake out of alignment. Observations of J0617 in the next 10 years should put this idea to the test. "If the neutron star was born off-center and if the wake is being pushed around by cross-winds, the neutron star should be moving close to vertically, away from the center of the supernova remnant. Now we wait and see," said Gaensler. Chandra X-ray Image of J0617 in IC 443 Chandra X-ray Image of J0617 in IC 443 Another group, led by Margarita Karovska, also of the CfA, has concentrated on other, previously unnoticed intriguing features of J0617. At a recent conference on neutron stars in London, England, they announced their findings, which include a thin filament of cooler gas that appears to extend from the neutron star along the long axis of its wake, and a second point-like feature embedded in the X-ray nebula around the neutron star. "There are a number of puzzling observational features associated with this system crying out for longer observations," said Karovska. Other members of the Gaensler team were S. Chatterjee and P. O. Slane (CfA), E. van der Swaluw (Royal Netherlands Meteorological Institute), F. Camilo (Columbia University), and J. P. Hughes (Rutgers University). Karovska's team included T. Clarke (Naval Research Laboratory), G. Pavlov (Penn State University), and M.C. Weisskopf and V. Zavlin of the Marshall Space Flight Center, Huntsville, Ala. which also manages the Chandra program for NASA's Science Mission Directorate. The Smithsonian Astrophysical Observatory provides science support and controls flight operations from the Chandra X-ray Center in Cambridge, Mass. Additional information and images can be found at: http://chandra.harvard.edu and http://chandra.nasa.gov For information about NASA and agency programs on the Web, visit: http://www.nasa.gov
Sallenger, Asbury; Wright, Wayne; Lillycrop, Jeff; Howd, Peter; Stockdon, Hilary; Guy, Kristy K.; Morgan, Karen
2007-01-01
Hurricane Katrina caused extreme changes to the barrier islands of the central Gulf of Mexico coast. Dauphin Island, Ala., migrated landward and stranded the remains of its oceanfront row homes in the sea. Chandeleur Islands, La., were completely stripped of their sand, leaving only marshy outcrops in the storm's wake.
ERIC Educational Resources Information Center
Çetin, Oguz
2016-01-01
In this study aiming to present a description based on science pre-service teachers' views related to use of Basic Information Technologies (BIT) in education and training, an interview is carried out with 21 pre-service science teachers who study in different classes in Faculty of Education, Nigde University. For this aim, improved interview form…
2008-05-01
BQs ) (see Appendix B for a listing of CCOs and BQs ). The grading guidance provided direction in determining performance on a scale of 1 to 7 (table...THU FRI SAT In-Proc./ Training/ Baseline/ Testing 1/ Testing 2/ Testing 3/ Recovery/ Day 1 Day 2 Day 3 Day 4 Day 5 Day 6 Day 7 00:00 Sleep Sleep...Checklist For use of this form, see ACT Aircrew Guide CCO BQ Crew Coordination Objectives/Basic Qualities Rating I Establish and Maintain Team Relationships
On I/O Virtualization Management
NASA Astrophysics Data System (ADS)
Danciu, Vitalian A.; Metzker, Martin G.
The quick adoption of virtualization technology in general and the advent of the Cloud business model entail new requirements on the structure and the configuration of back-end I/O systems. Several approaches to virtualization of I/O links are being introduced, which aim at implementing a more flexible I/O channel configuration without compromising performance. While previously the management of I/O devices could be limited to basic technical requirments (e.g. the establishment and termination of fixed-point links), the additional flexibility carries in its wake additional management requirements on the representation and control of I/O sub-systems.
Quantifying Leg Movement Activity During Sleep.
Ferri, Raffaele; Fulda, Stephany
2016-12-01
Currently, 2 sets of similar rules for recording and scoring leg movement (LM) exist, including periodic LM during sleep (PLMS) and periodic LM during wakefulness. The former were published in 2006 by a task force of the International Restless Legs Syndrome Study Group, and the second in 2007 by the American Academy of Sleep Medicine. This article reviews the basic recording methods, scoring rules, and computer-based programs for PLMS. Less frequent LM activities, such as alternating leg muscle activation, hypnagogic foot tremor, high-frequency LMs, and excessive fragmentary myoclonus are briefly described. Copyright © 2016 Elsevier Inc. All rights reserved.
Lee, S.; Churchfield, M.; Sirnivas, S.; ...
2015-06-18
A team of researchers from the National Renewable Energy Laboratory and Statoil used large-eddy simulations to numerically investigate the merging wakes from upstream offshore wind turbines. Merging wakes are typical phenomena in wind farm flows in which neighboring turbine wakes consolidate to form complex flow patterns that are as yet not well understood. In the present study, three 6-MW turbines in a row were subjected to a neutrally stable atmospheric boundary layer flow. As a result, the wake from the farthest upstream turbine conjoined the downstream wake, which significantly altered the subsequent velocity deficit structures, turbulence intensity, and the globalmore » meandering behavior. The complexity increased even more when the combined wakes from the two upstream turbines mixed with the wake generated by the last turbine, thereby forming a "triplet" structure. Although the influence of the wake generated by the first turbine decayed with downstream distance, the mutated wakes from the second turbine continued to influence the downstream wake. Two mirror-image angles of wind directions that yielded partial wakes impinging on the downstream turbines yielded asymmetric wake profiles that could be attributed to the changing flow directions in the rotor plane induced by the Coriolis force. In conclusion, the turbine wakes persisted for extended distances in the present study, which is a result of low aerodynamic surface roughness typically found in offshore conditions« less
Neural Control of the Upper Airway: Respiratory and State-Dependent Mechanisms
Kubin, Leszek
2017-01-01
Upper airway muscles subserve many essential for survival orofacial behaviors, including their important role as accessory respiratory muscles. In the face of certain predisposition of craniofacial anatomy, both tonic and phasic inspiratory activation of upper airway muscles is necessary to protect the upper airway against collapse. This protective action is adequate during wakefulness, but fails during sleep which results in recurrent episodes of hypopneas and apneas, a condition known as the obstructive sleep apnea syndrome (OSA). Although OSA is almost exclusively a human disorder, animal models help unveil the basic principles governing the impact of sleep on breathing and upper airway muscle activity. This article discusses the neuroanatomy, neurochemistry, and neurophysiology of the different neuronal systems whose activity changes with sleep-wake states, such as the noradrenergic, serotonergic, cholinergic, orexinergic, histaminergic, GABAergic and glycinergic, and their impact on central respiratory neurons and upper airway motoneurons. Observations of the interactions between sleep-wake states and upper airway muscles in healthy humans and OSA patients are related to findings from animal models with normal upper airway, and various animal models of OSA, including the chronic-intermittent hypoxia model. Using a framework of upper airway motoneurons being under concurrent influence of central respiratory, reflex and state-dependent inputs, different neurotransmitters, and neuropeptides are considered as either causing a sleep-dependent withdrawal of excitation from motoneurons or mediating an active, sleep-related inhibition of motoneurons. Information about the neurochemistry of state-dependent control of upper airway muscles accumulated to date reveals fundamental principles and may help understand and treat OSA. PMID:27783860
ERIC Educational Resources Information Center
Busch, Phyllis S.
1985-01-01
Provides directions for basic science experiments which demonstrate the rain cycle, fundamentals of cloud formation, and testing for the presence of acidity in local rainwater. Describes materials required, step-by-step instructions, and discussion topics. (NEC)
On the Effects of Wind Turbine Wake Skew Caused by Wind Veer: Preprint
DOE Office of Scientific and Technical Information (OSTI.GOV)
Churchfield, Matthew J; Sirnivas, Senu
Because of Coriolis forces caused by the Earth's rotation, the structure of the atmospheric boundary layer often contains wind-direction change with height, also known as wind-direction veer. Under low turbulence conditions, such as in stably stratified atmospheric conditions, this veer can be significant, even across the vertical extent of a wind turbine's rotor disk. The veer then causes the wind turbine wake to skew as it advects downstream. This wake skew has been observed both experimentally and numerically. In this work, we attempt to examine the wake skewing process in some detail, and quantify how differently a skewed wake versusmore » a non skewed wake affects a downstream turbine. We do this by performing atmospheric large-eddy simulations to create turbulent inflow winds with and without veer. In the veer case, there is a roughly 8 degree wind direction change across the turbine rotor. We then perform subsequent large-eddy simulations using these inflow data with an actuator line rotor model to create wakes. The turbine modeled is a large, modern, offshore, multimegawatt turbine. We examine the unsteady wake data in detail and show that the skewed wake recovers faster than the non skewed wake. We also show that the wake deficit does not skew to the same degree that a passive tracer would if subject to veered inflow. Last, we use the wake data to place a hypothetical turbine 9 rotor diameters downstream by running aeroelastic simulations with the simulated wake data. We see differences in power and loads if this downstream turbine is subject to a skewed or non skewed wake. We feel that the differences observed between the skewed and nonskewed wake are important enough that the skewing effect should be included in engineering wake models.« less
On the Effects of Wind Turbine Wake Skew Caused by Wind Veer
DOE Office of Scientific and Technical Information (OSTI.GOV)
Churchfield, Matthew J; Sirnivas, Senu
Because of Coriolis forces caused by the Earth's rotation, the structure of the atmospheric boundary layer often contains wind-direction change with height, also known as wind-direction veer. Under low turbulence conditions, such as in stably stratified atmospheric conditions, this veer can be significant, even across the vertical extent of a wind turbine's rotor disk. The veer then causes the wind turbine wake to skew as it advects downstream. This wake skew has been observed both experimentally and numerically. In this work, we attempt to examine the wake skewing process in some detail, and quantify how differently a skewed wake versusmore » a non skewed wake affects a downstream turbine. We do this by performing atmospheric large-eddy simulations to create turbulent inflow winds with and without veer. In the veer case, there is a roughly 8 degree wind direction change across the turbine rotor. We then perform subsequent large-eddy simulations using these inflow data with an actuator line rotor model to create wakes. The turbine modeled is a large, modern, offshore, multimegawatt turbine. We examine the unsteady wake data in detail and show that the skewed wake recovers faster than the non skewed wake. We also show that the wake deficit does not skew to the same degree that a passive tracer would if subject to veered inflow. Last, we use the wake data to place a hypothetical turbine 9 rotor diameters downstream by running aeroelastic simulations with the simulated wake data. We see differences in power and loads if this downstream turbine is subject to a skewed or non skewed wake. We feel that the differences observed between the skewed and nonskewed wake are important enough that the skewing effect should be included in engineering wake models.« less
Basic sciences agonize in Turkey!
NASA Astrophysics Data System (ADS)
Akdemir, Fatma; Araz, Asli; Akman, Ferdi; Durak, Rıdvan
2016-04-01
In this study, changes from past to present in the departments of physics, chemistry, biology and mathematics, which are considered as the basic sciences in Turkey, are shown. The importance of basic science for the country emphasized and the status of our country was discussed with a critical perspective. The number of academic staff, the number of students, opened quotas according to years for these four departments at universities were calculated and analysis of the resulting changes were made. In examined graphics changes to these four departments were similar. Especially a significant change was observed in the physics department. Lack of jobs employing young people who have graduated from basic science is also an issue that must be discussed. There are also qualitative results of this study that we have discussed as quantitative. Psychological problems caused by unemployment have become a disease among young people. This study was focused on more quantitative results. We have tried to explain the causes of obtained results and propose solutions.
Nuclear fission: the interplay of science and technology.
Stoneham, A M
2010-07-28
When the UK's Calder Hall nuclear power station was connected to the grid in 1956, the programmes that made this possible involved a powerful combination of basic and applied research. Both the science and the engineering were novel, addressing new and challenging problems. That the last Calder Hall reactor was shut down only in 2003 attests to the success of the work. The strengths of bringing basic science to bear on applications continued to be recognized until the 1980s, when government and management fashions changed. This paper identifies a few of the technology challenges, and shows how novel basic science emerged from them and proved essential in their resolution. Today, as the threat of climate change becomes accepted, it has become clear that there is no credible solution without nuclear energy. The design and construction of new fission reactors will need continuing innovation, with the interplay between the science and technology being a crucial component.
Recent NASA Wake-Vortex Flight Tests, Flow-Physics Database and Wake-Development Analysis
NASA Technical Reports Server (NTRS)
Vicroy, Dan D.; Vijgen, Paul M.; Reimer, Heidi M.; Gallegos, Joey L.; Spalart, Philippe R.
1998-01-01
A series of flight tests over the ocean of a four engine turboprop airplane in the cruise configuration have provided a data set for improved understanding of wake vortex physics and atmospheric interaction. An integrated database has been compiled for wake characterization and validation of wake-vortex computational models. This paper describes the wake-vortex flight tests, the data processing, the database development and access, and results obtained from preliminary wake-characterization analysis using the data sets.
Preparing medical students for future learning using basic science instruction.
Mylopoulos, Maria; Woods, Nicole
2014-07-01
The construct of 'preparation for future learning' (PFL) is understood as the ability to learn new information from available resources, relate new learning to past experiences and demonstrate innovation and flexibility in problem solving. Preparation for future learning has been proposed as a key competence of adaptive expertise. There is a need for educators to ensure that opportunities are provided for students to develop PFL ability and that assessments accurately measure the development of this form of competence. The objective of this research was to compare the relative impacts of basic science instruction and clinically focused instruction on performance on a PFL assessment (PFLA). This study employed a 'double transfer' design. Fifty-one pre-clerkship students were randomly assigned to either basic science instruction or clinically focused instruction to learn four categories of disease. After completing an initial assessment on the learned material, all participants received clinically focused instruction for four novel diseases and completed a PFLA. The data from the initial assessment and the PFLA were submitted to independent-sample t-tests. Mean ± standard deviation [SD] scores on the diagnostic cases in the initial assessment were similar for participants in the basic science (0.65 ± 0.11) and clinical learning (0.62 ± 0.11) conditions. The difference was not significant (t[42] = 0.90, p = 0.37, d = 0.27). Analysis of the diagnostic cases on the PFLA revealed significantly higher mean ± SD scores for participants in the basic science learning condition (0.72 ± 0.14) compared with those in the clinical learning condition (0.63 ± 0.15) (t[42] = 2.02, p = 0.05, d = 0.62). Our results show that the inclusion of basic science instruction enhanced the learning of novel related content. We discuss this finding within the broader context of research on basic science instruction, development of adaptive expertise and assessment in medical education. © 2014 John Wiley & Sons Ltd.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Doubrawa, Paula; Barthelmie, Rebecca J.; Wang, Hui
Understanding the detailed dynamics of wind turbine wakes is critical to predicting the performance and maximizing the efficiency of wind farms. This knowledge requires atmospheric data at a high spatial and temporal resolution, which are not easily obtained from direct measurements. Therefore, research is often based on numerical models, which vary in fidelity and computational cost. The simplest models produce axisymmetric wakes and are only valid beyond the near wake. Higher-fidelity results can be obtained by solving the filtered Navier-Stokes equations at a resolution that is sufficient to resolve the relevant turbulence scales. This work addresses the gap between thesemore » two extremes by proposing a stochastic model that produces an unsteady asymmetric wake. The model is developed based on a large-eddy simulation (LES) of an offshore wind farm. Because there are several ways of characterizing wakes, the first part of this work explores different approaches to defining global wake characteristics. From these, a model is developed that captures essential features of a LES-generated wake at a small fraction of the cost. The synthetic wake successfully reproduces the mean characteristics of the original LES wake, including its area and stretching patterns, and statistics of the mean azimuthal radius. The mean and standard deviation of the wake width and height are also reproduced. This preliminary study focuses on reproducing the wake shape, while future work will incorporate velocity deficit and meandering, as well as different stability scenarios.« less
Dissipation of turbulence in the wake of a wind turbine
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lundquist, J. K.; Bariteau, L.
The wake of a wind turbine is characterized by increased turbulence and decreased wind speed. Turbines are generally deployed in large groups in wind farms, and so the behaviour of an individual wake as it merges with other wakes and propagates downwind is critical in assessing wind-farm power production. This evolution depends on the rate of turbulence dissipation in the wind-turbine wake, which has not been previously quantified in field-scale measurements. In situ measurements of winds and turbulence dissipation from the wake region of a multi-MW turbine were collected using a tethered lifting system (TLS) carrying a payload of high-ratemore » turbulence probes. Ambient flow measurements were provided from sonic anemometers on a meteorological tower located near the turbine. Good agreement between the tower measurements and the TLS measurements was established for a case without a wind-turbine wake. When an operating wind turbine is located between the tower and the TLS so that the wake propagates to the TLS, the TLS measures dissipation rates one to two orders of magnitude higher in the wake than outside of the wake. These data, collected between two and three rotor diameters D downwind of the turbine, document the significant enhancement of turbulent kinetic energy dissipation rate within the wind-turbine wake. These wake measurements suggest that it may be useful to pursue modelling approaches that account for enhanced dissipation. Furthermore. comparisons of wake and non-wake dissipation rates to mean wind speed, wind-speed variance, and turbulence intensity are presented to facilitate the inclusion of these measurements in wake modelling schemes.« less
Dissipation of Turbulence in the Wake of a Wind Turbine
NASA Astrophysics Data System (ADS)
Lundquist, J. K.; Bariteau, L.
2015-02-01
The wake of a wind turbine is characterized by increased turbulence and decreased wind speed. Turbines are generally deployed in large groups in wind farms, and so the behaviour of an individual wake as it merges with other wakes and propagates downwind is critical in assessing wind-farm power production. This evolution depends on the rate of turbulence dissipation in the wind-turbine wake, which has not been previously quantified in field-scale measurements. In situ measurements of winds and turbulence dissipation from the wake region of a multi-MW turbine were collected using a tethered lifting system (TLS) carrying a payload of high-rate turbulence probes. Ambient flow measurements were provided from sonic anemometers on a meteorological tower located near the turbine. Good agreement between the tower measurements and the TLS measurements was established for a case without a wind-turbine wake. When an operating wind turbine is located between the tower and the TLS so that the wake propagates to the TLS, the TLS measures dissipation rates one to two orders of magnitude higher in the wake than outside of the wake. These data, collected between two and three rotor diameters downwind of the turbine, document the significant enhancement of turbulent kinetic energy dissipation rate within the wind-turbine wake. These wake measurements suggest that it may be useful to pursue modelling approaches that account for enhanced dissipation. Comparisons of wake and non-wake dissipation rates to mean wind speed, wind-speed variance, and turbulence intensity are presented to facilitate the inclusion of these measurements in wake modelling schemes.
Dissipation of turbulence in the wake of a wind turbine
Lundquist, J. K.; Bariteau, L.
2014-11-06
The wake of a wind turbine is characterized by increased turbulence and decreased wind speed. Turbines are generally deployed in large groups in wind farms, and so the behaviour of an individual wake as it merges with other wakes and propagates downwind is critical in assessing wind-farm power production. This evolution depends on the rate of turbulence dissipation in the wind-turbine wake, which has not been previously quantified in field-scale measurements. In situ measurements of winds and turbulence dissipation from the wake region of a multi-MW turbine were collected using a tethered lifting system (TLS) carrying a payload of high-ratemore » turbulence probes. Ambient flow measurements were provided from sonic anemometers on a meteorological tower located near the turbine. Good agreement between the tower measurements and the TLS measurements was established for a case without a wind-turbine wake. When an operating wind turbine is located between the tower and the TLS so that the wake propagates to the TLS, the TLS measures dissipation rates one to two orders of magnitude higher in the wake than outside of the wake. These data, collected between two and three rotor diameters D downwind of the turbine, document the significant enhancement of turbulent kinetic energy dissipation rate within the wind-turbine wake. These wake measurements suggest that it may be useful to pursue modelling approaches that account for enhanced dissipation. Furthermore. comparisons of wake and non-wake dissipation rates to mean wind speed, wind-speed variance, and turbulence intensity are presented to facilitate the inclusion of these measurements in wake modelling schemes.« less
Lidar-based wake tracking for closed-loop wind farm control
NASA Astrophysics Data System (ADS)
Raach, Steffen; Schlipf, David; Cheng, Po Wen
2016-09-01
This work presents two advancements towards closed-loop wake redirecting of a wind turbine. First, a model-based estimation approach is presented which uses a nacelle-based lidar system facing downwind to obtain information about the wake. A reduced order wake model is described which is then used in the estimation to track the wake. The tracking is demonstrated with lidar measurement data from an offshore campaign and with simulated lidar data from a SOWFA simulation. Second, a controller for closed-loop wake steering is presented. It uses the wake tracking information to set the yaw actuator of the wind turbine to redirect the wake to a desired position. Altogether, this paper aims to present the concept of closed-loop wake redirecting and gives a possible solution to it.
Wake measurements in a strong adverse pressure gradient
NASA Technical Reports Server (NTRS)
Hoffenberg, R.; Sullivan, John P.; Schneider, S. P.
1994-01-01
The behavior of wakes in adverse pressure gradients is critical to the performance of high-lift systems for transport aircraft. Wake deceleration is known to lead to sudden thickening and the onset of reversed flow; this 'wake bursting' phenomenon can occur while surface flows remain attached. Although 'wake bursting' is known to be important for high-lift systems, no detailed measurements of 'burst' wakes have ever been reported. Wake bursting has been successfully achieved in the wake of a flat plate as it decelerated in a two-dimensional diffuser, whose sidewalls were forced to remain attached by use of slot blowing. Pilot probe surveys, L.D.V. measurements, and flow visualization have been used to investigate the physics of this decelerated wake, through the onset of reversed flow.
Town Meeting on Plasma Physics at the National Science Foundation
NASA Astrophysics Data System (ADS)
2015-11-01
We invite you to the Town Meeting on the role of the National Science Foundation (NSF) in supporting basic and applied research in Plasma Physics in the U.S. The overarching goal of NSF is to promote the progress of science and to enable training of the next generation of scientists and engineers at US colleges and universities. In this context, the role of the NSF Physics Division in leading the nearly 20 year old NSF/DOE Partnership in Basic Plasma Science and Engineering serves as an example of the long history of NSF support for basic plasma physics research. Yet, the NSF interest in maintaining a healthy university research base in plasma sciences extends across the Foundation. A total of five NSF Divisions are participating in the most recent Partnership solicitation, and a host of other multi-disciplinary and core programs provide opportunities for scientists to perform research on applications of plasma physics to Space & Solar Physics, Astrophysics, Accelerator Science, Material Science, Plasma Medicine, and many sub-disciplines within Engineering. This Town Meeting will provide a chance to discuss the full range of relevant NSF funding opportunities, and to begin a conversation on the present and future role of NSF in stewarding basic plasma science and engineering research at US colleges and universities. We would like to particularly encourage early career scientists and graduate students to participate in this Town Meeting, though everyone is invited to join what we hope to be a lively discussion.
Evolving the future: Toward a science of intentional change
Wilson, David Sloan; Hayes, Steven C.; Biglan, Anthony; Embry, Dennis D.
2015-01-01
Humans possess great capacity for behavioral and cultural change, but our ability to manage change is still limited. This article has two major objectives: first, to sketch a basic science of intentional change centered on evolution; second, to provide examples of intentional behavioral and cultural change from the applied behavioral sciences, which are largely unknown to the basic sciences community. All species have evolved mechanisms of phenotypic plasticity that enable them to respond adaptively to their environments. Some mechanisms of phenotypic plasticity count as evolutionary processes in their own right. The human capacity for symbolic thought provides an inheritance system having the same kind of combinatorial diversity as does genetic recombination and antibody formation. Taking these propositions seriously allows an integration of major traditions within the basic behavioral sciences, such as behaviorism, social constructivism, social psychology, cognitive psychology, and evolutionary psychology, which are often isolated and even conceptualized as opposed to one another. The applied behavioral sciences include well-validated examples of successfully managing behavioral and cultural change at scales ranging from individuals to small groups to large populations. However, these examples are largely unknown beyond their disciplinary boundaries, for lack of a unifying theoretical framework. Viewed from an evolutionary perspective, they are examples of managing evolved mechanisms of phenotypic plasticity, including open-ended processes of variation and selection. Once the many branches of the basic and applied behavioral sciences become conceptually unified, we are closer to a science of intentional change than one might think. PMID:24826907
Ada in Introductory Computer Science Courses
1993-01-01
Ada by Daniel F. Stubbs and Neil W. Webre Course Objective: To introduce the students to the basic classical data structures of computer science...Introduction to Ada, Chapman & Hall, 1993, London Dale/Weems/McCormick, Programming and Problem Solving with Ada, D. C. Heath and Company, 1994, MA Feldman...Daniel F. Stubbs and Neil W. Webre - Course Objective: To introduce the students to the basic classical data structures of computer science
ERIC Educational Resources Information Center
Ayasra, Ahmad
2015-01-01
This study aimed to investigate obstacles that prevent implementation of science curriculum which was developed within the Education Reform for the Knowledge Economy project (ErfKE). To achieve this, a purposeful sample consisted of four teachers of science for the basic stage in the town located in the north of Jordan in the first semester of the…
Future of fundamental discovery in US biomedical research
Levitt, Michael; Levitt, Jonathan M.
2017-01-01
Young researchers are crucially important for basic science as they make unexpected, fundamental discoveries. Since 1982, we find a steady drop in the number of grant-eligible basic-science faculty [principal investigators (PIs)] younger than 46. This fall occurred over a 32-y period when inflation-corrected congressional funds for NIH almost tripled. During this time, the PI success ratio (fraction of basic-science PIs who are R01 grantees) dropped for younger PIs (below 46) and increased for older PIs (above 55). This age-related bias seems to have caused the steady drop in the number of young basic-science PIs and could reduce future US discoveries in fundamental biomedical science. The NIH recognized this bias in its 2008 early-stage investigator (ESI) policy to fund young PIs at higher rates. We show this policy is working and recommend that it be enhanced by using better data. Together with the National Institute of General Medical Sciences (NIGMS) Maximizing Investigators’ Research Award (MIRA) program to reward senior PIs with research time in exchange for less funding, this may reverse a decades-long trend of more money going to older PIs. To prepare young scientists for increased demand, additional resources should be devoted to transitional postdoctoral fellowships already offered by NIH. PMID:28584129
Development of a Wake Vortex Spacing System for Airport Capacity Enhancement and Delay Reduction
NASA Technical Reports Server (NTRS)
Hinton, David A.; OConnor, Cornelius J.
2000-01-01
The Terminal Area Productivity project has developed the technologies required (weather measurement, wake prediction, and wake measurement) to determine the aircraft spacing needed to prevent wake vortex encounters in various weather conditions. The system performs weather measurements, predicts bounds on wake vortex behavior in those conditions, derives safe wake spacing criteria, and validates the wake predictions with wake vortex measurements. System performance to date indicates that the potential runway arrival rate increase with Aircraft VOrtex Spacing System (AVOSS), considering common path effects and ATC delivery variance, is 5% to 12% depending on the ratio of large and heavy aircraft. The concept demonstration system, using early generation algorithms and minimal optimization, is performing the wake predictions with adequate robustness such that only 4 hard exceedances have been observed in 1235 wake validation cases. This performance demonstrates the feasibility of predicting wake behavior bounds with multiple uncertainties present, including the unknown aircraft weight and speed, weather persistence between the wake prediction and the observations, and the location of the weather sensors several kilometers from the approach location. A concept for the use of the AVOSS system for parallel runway operations has been suggested, and an initial study at the JFK International Airport suggests that a simplified AVOSS system can be successfully operated using only a single lidar as both the weather sensor and the wake validation instrument. Such a selfcontained AVOSS would be suitable for wake separation close to the airport, as is required for parallel approach concepts such as SOIA.
Optometry Basic Science Curricula: Current Status.
ERIC Educational Resources Information Center
Berman, Morris S.
1991-01-01
A national survey of optometry schools (n=10) concerning the status of basic biological science instruction provides insight into manpower, curriculum, learning resources, and budgetary support currently available. Results indicate that major changes must occur and that a national effort will be needed to support them. (Author/MSE)
Integrating Basic Science and Clinical Teaching for Third-Year Medical Students.
ERIC Educational Resources Information Center
Croen, Lila G.; And Others
1986-01-01
A 2-month program for third-year students at Yeshiva's Albert Einstein College of Medicine that provides a model for integrating basic sciences and clinical training is described. It demonstrates the importance of lifelong learning in a field that constantly changes. (Author/MLW)
Global Security, Medical Isotopes, and Nuclear Science
NASA Astrophysics Data System (ADS)
Ahle, Larry
2007-10-01
Over the past century basic nuclear science research has led to the use of radioactive isotopes into a wide variety of applications that touch our lives everyday. Some are obvious, such as isotopes for medical diagnostics and treatment. Others are less so, such as National/Global security issues. And some we take for granted, like the small amount of 241 Am that is in every smoke detector. At the beginning of this century, we are in a position where the prevalence and importance of some applications of nuclear science are pushing the basic nuclear science community for improved models and nuclear data. Yet, at the same time, the push by the basic nuclear science community to study nuclei that are farther and farther away from stability also offer new opportunities for many applications. This talk will look at several global security applications of nuclear science, summarizing current R&D and need for improved nuclear data It will also look at how applications of nuclear science, such as to medicine, will benefit from the push for more and more powerful radioactive ion beam facilities.
NASA Astrophysics Data System (ADS)
Anderson, Paul; Evans, Charles
2017-01-01
A method to compute the stress-energy tensor for a quantized massless minimally coupled scalar field outside the event horizon of a 4-D black hole that forms from the collapse of a spherically symmetric null shell is given. The method is illustrated in the corresponding 2-D case which is mathematically similar but is simple enough that the calculations can be done analytically. The approach to the Unruh state at late times is discussed. National Science Foundation Grant No. PHY-1505875 to Wake Forest University and National Science Foundation Grant No. PHY-1506182 to the University of North Carolina, Chapel Hill
NASA Technical Reports Server (NTRS)
Perras, G. H.; Dasey, T. J.
2000-01-01
Potential adaptive wake vortex spacing systems may need to rely on wake vortex decay rather than wake vortex transport in reducing wake separations. A wake vortex takeoff-spacing system in particular will need to rely on wake decay. Ambient turbulence is the primary influence on wake decay away from the ground. This study evaluated 18 months of ambient turbulence measurements at Dallas/Ft. Worth (DFW) Airport. The measurements show minor variation in the turbulence levels at various times of the year or times of the day for time periods when a departure system could be used. Arrival system operation was also examined, and a slightly lower overall turbulence level was found as compared to departure system benefit periods. The Sarpkaya model, a validated model of wake vortex behavior, was applied to various turbulence levels and compared to the DFW turbulence statistics. The results show that wake vortices from heavy aircraft on takeoff should dissipate within one minute for the majority of the time and will rarely last two minutes. These results will need to be verified by wake vortex measurements on departure.
The NASA Low-Pressure Turbine Flow Physics Program
NASA Technical Reports Server (NTRS)
Ashpis, David E.
1998-01-01
An overview of the NASA Lewis Low-Pressure Turbine (LPT) Flow Physics Program will be presented. The program was established in response to the aero-engine industry's need for improved LPT efficiency and designs. Modern jet engines have four to seven LPT stages, significantly contributing to engine weight. In addition, there is a significant efficiency degradation between takeoff and cruise conditions, of up to 2 points. Reducing the weight and part count of the LPT and minimizing the efficiency degradation will translate into fuel savings. Accurate prediction methods of LPT flows and losses are needed to accomplish those improvements. The flow in LPT passages is at low Reynolds number, and is dominated by interplay of three basic mechanisms: transition, separation and wake interaction. The affecting parameters traditionally considered are Reynolds number, freestream turbulence intensity, wake frequency parameter, and the pressure distribution (loading). Three-dimensional effects and additional parameters, particularly turbulence characteristics like length scales, spectra and other statistics, as well as wake turbulence intensity and properties also play a role. The flow of most interest is on the suction surface, where large losses are generated as the flow tends to separate at the low Reynolds numbers. Ignoring wakes, a common flow scenario, there is laminar separation, followed by transition on the separation bubble and turbulent reattachment. If transition starts earlier the separation will be eliminated and the boundary layer will be attached leading to the well known bypass transition issues. In contrast, transition over a separation bubble is closer to free shear layer transition and was not investigated as well, particularly in the turbine environment. Unsteadiness created by wakes complicates the picture. Wakes induce earlier transition, and the calmed regions trailing the induced turbulent spots can delay or eliminate separation via shear stress modification. Three-dimensional flow physics and geometry will have strong effects. Altogether a very complex and challenging problem emerges. The objective of the program is to provide improved models and physical understanding of the complex flow, which are essential for accurate prediction of flow and losses in the LPT. Experimental, computational and analytical work as complementing and augmenting approaches are used. The program involves industry, universities and research institutes, and other government laboratories. It is characterized by strong interaction among participants, quick dissemination of results, and responsiveness to industry's needs. The presentation will describe the work elements. Highlighting some activities in progress are experiments on simulated blade suction surface in low-speed wind tunnels, on curved wall, and on a flat-plate, both with pressure gradient. In the area of computation, assessment of existing models is performed using RANS (Reynolds Averaged Navier Stokes) simulations. Laminar flow DNS was completed. Analytical studies of instability and receptivity in attached and separated flows were started. In the near future the program is moving to include wake effects and development of improved modeling. Experimental work in preparation stages are: (1) Addition of wakes to the curved tunnel experiment; (2) Low-speed rotating rig experiment on GE90 engine LPT; and (3) Transonic cascade. In the area of computation, it is expected to move from model assessment towards development of improved models. In addition, a new project of Large Eddy Simulation (LES) of LPT is to begin and will provide numerical data bases. It is planned to implement the emerging improved models in a multistage turbomachinery code and to validate against the GE90 engine LPT.
A brief simulation intervention increasing basic science and clinical knowledge.
Sheakley, Maria L; Gilbert, Gregory E; Leighton, Kim; Hall, Maureen; Callender, Diana; Pederson, David
2016-01-01
The United States Medical Licensing Examination (USMLE) is increasing clinical content on the Step 1 exam; thus, inclusion of clinical applications within the basic science curriculum is crucial. Including simulation activities during basic science years bridges the knowledge gap between basic science content and clinical application. To evaluate the effects of a one-off, 1-hour cardiovascular simulation intervention on a summative assessment after adjusting for relevant demographic and academic predictors. This study was a non-randomized study using historical controls to evaluate curricular change. The control group received lecture (n l=515) and the intervention group received lecture plus a simulation exercise (n l+s=1,066). Assessment included summative exam questions (n=4) that were scored as pass/fail (≥75%). USMLE-style assessment questions were identical for both cohorts. Descriptive statistics for variables are presented and odds of passage calculated using logistic regression. Undergraduate grade point ratio, MCAT-BS, MCAT-PS, age, attendance at an academic review program, and gender were significant predictors of summative exam passage. Students receiving the intervention were significantly more likely to pass the summative exam than students receiving lecture only (P=0.0003). Simulation plus lecture increases short-term understanding as tested by a written exam. A longitudinal study is needed to assess the effect of a brief simulation intervention on long-term retention of clinical concepts in a basic science curriculum.
A brief simulation intervention increasing basic science and clinical knowledge.
Sheakley, Maria L; Gilbert, Gregory E; Leighton, Kim; Hall, Maureen; Callender, Diana; Pederson, David
2016-01-01
Background The United States Medical Licensing Examination (USMLE) is increasing clinical content on the Step 1 exam; thus, inclusion of clinical applications within the basic science curriculum is crucial. Including simulation activities during basic science years bridges the knowledge gap between basic science content and clinical application. Purpose To evaluate the effects of a one-off, 1-hour cardiovascular simulation intervention on a summative assessment after adjusting for relevant demographic and academic predictors. Methods This study was a non-randomized study using historical controls to evaluate curricular change. The control group received lecture (n l =515) and the intervention group received lecture plus a simulation exercise (n l+s =1,066). Assessment included summative exam questions (n=4) that were scored as pass/fail (≥75%). USMLE-style assessment questions were identical for both cohorts. Descriptive statistics for variables are presented and odds of passage calculated using logistic regression. Results Undergraduate grade point ratio, MCAT-BS, MCAT-PS, age, attendance at an academic review program, and gender were significant predictors of summative exam passage. Students receiving the intervention were significantly more likely to pass the summative exam than students receiving lecture only (P=0.0003). Discussion Simulation plus lecture increases short-term understanding as tested by a written exam. A longitudinal study is needed to assess the effect of a brief simulation intervention on long-term retention of clinical concepts in a basic science curriculum.
Airloads, wakes, and aeroelasticity
NASA Technical Reports Server (NTRS)
Johnson, Wayne
1990-01-01
Fundamental considerations regarding the theory of modeling of rotary wing airloads, wakes, and aeroelasticity are presented. The topics covered are: airloads and wakes, including lifting-line theory, wake models and nonuniform inflow, free wake geometry, and blade-vortex interaction; aerodynamic and wake models for aeroelasticity, including two-dimensional unsteady aerodynamics and dynamic inflow; and airloads and structural dynamics, including comprehensive airload prediction programs. Results of calculations and correlations are presented.
Large-eddy simulation of wind turbine wake interactions on locally refined Cartesian grids
NASA Astrophysics Data System (ADS)
Angelidis, Dionysios; Sotiropoulos, Fotis
2014-11-01
Performing high-fidelity numerical simulations of turbulent flow in wind farms remains a challenging issue mainly because of the large computational resources required to accurately simulate the turbine wakes and turbine/turbine interactions. The discretization of the governing equations on structured grids for mesoscale calculations may not be the most efficient approach for resolving the large disparity of spatial scales. A 3D Cartesian grid refinement method enabling the efficient coupling of the Actuator Line Model (ALM) with locally refined unstructured Cartesian grids adapted to accurately resolve tip vortices and multi-turbine interactions, is presented. Second order schemes are employed for the discretization of the incompressible Navier-Stokes equations in a hybrid staggered/non-staggered formulation coupled with a fractional step method that ensures the satisfaction of local mass conservation to machine zero. The current approach enables multi-resolution LES of turbulent flow in multi-turbine wind farms. The numerical simulations are in good agreement with experimental measurements and are able to resolve the rich dynamics of turbine wakes on grids containing only a small fraction of the grid nodes that would be required in simulations without local mesh refinement. This material is based upon work supported by the Department of Energy under Award Number DE-EE0005482 and the National Science Foundation under Award number NSF PFI:BIC 1318201.
NASA Technical Reports Server (NTRS)
Sengupta, Anita; Wernet, Mark; Roeder, James; Kelsch, Richard; Witkowski, Al; Jones, Thomas
2009-01-01
Supersonic wind tunnel testing of Viking-type 0.8 m Disk-Gap-Band (DGB) parachutes was conducted in the NASA Glenn Research Center 10'x10' wind-tunnel. The tests were conducted in support of the Mars Science Laboratory Parachute Decelerator System development and qualification program. The aerodynamic coupling of the entry-vehicle wake to parachute flow-field is under investigation to determine the cause and functional dependence of a supersonic canopy breathing phenomenon referred to as area oscillations, characteristic of DGB's above Mach 1.5 operation. Four percent of full-scale parachutes (0.8 m) were constructed similar to the flight-article in material and construction techniques. The parachutes were attached to a 70-deg sphere-cone entry-vehicle to simulate the Mars flight configuration. The parachutes were tested in the wind-tunnel from Mach 2 to 2.5 in a Reynolds number range of 2x105 to 1x106, representative of a Mars deployment. Three different test configurations were investigated. In the first two configurations, the parachutes were constrained horizontally through the vent region to measure canopy breathing and wake interaction for fixed trim angles of 0 and 10 degrees from the free-stream. In the third configuration the parachute was unconstrained, permitted to trim and cone, similar to free-flight (but capsule motion is constrained), varying its alignment relative to the entry-vehicle wake. Non-intrusive test diagnostics were chosen to quantify parachute performance and provide insight into the flow field structure. An in-line loadcell provided measurement of unsteady and mean drag. Shadowgraph of the upstream parachute flow field was used to capture bow-shock motion and wake coupling. Particle image velocimetry provided first and second order flow field statistics over a planar region of the flow field, just upstream of the parachute. A photogrammetric technique was used to quantify fabric motion using multiple high speed video cameras to record the location in time and space of reflective targets placed on the canopy interior. The experimental findings including an updated drag model and the physical basis of the area oscillation phenomenon will be discussed.
A late wake time phase delays the human dim light melatonin rhythm.
Burgess, Helen J; Eastman, Charmane I
2006-03-13
Short sleep/dark durations, due to late bedtimes or early wake times or both, are common in modern society. We have previously shown that a series of days with a late bedtime phase delays the human dim light melatonin rhythm, as compared to a series of days with an early bedtime, despite a fixed wake time. Here we compared the effect of an early versus late wake time with a fixed bedtime on the human dim light melatonin rhythm. Fourteen healthy subjects experienced 2 weeks of short 6h nights with an early wake time fixed at their habitual weekday wake time and 2 weeks of long 9 h nights with a wake time that occurred 3h later than the early wake time, in counterbalanced order. We found that after 2 weeks with the late wake time, the dim light melatonin onset delayed by 2.4 h and the dim light melatonin offset delayed by 2.6 h (both p < 0.001), as compared to after 2 weeks with the early wake time. These results highlight the substantial influence that wake time, likely via the associated morning light exposure, has on the timing of the human circadian clock. Furthermore, the results suggest that when people truncate their sleep by waking early their circadian clocks phase advance and when people wake late their circadian clocks phase delay.
ERIC Educational Resources Information Center
Science and Children, 1981
1981-01-01
Reviews four science curriculum materials. "Human Issues in Science" presents social consequences of science and technological developments. "Experiences in Science" contains duplicating masters to supplement basic science programs. "Outdoor Areas as Learning Laboratories" includes activities for local environments. "The Science Cookbook" uses…
Separation of Lift-Generated Vortex Wakes Into Two Diverging Parts
NASA Technical Reports Server (NTRS)
Rossow, Vernon J.; Brown, Anthony P.
2010-01-01
As part of an ongoing study of the spreading rate of lift-generated vortex wakes, the present investigation considers possible reasons as to why segments of lift-generated wakes sometimes depart from the main part of the wake to move rapidly in either an upward or downward direction. It is assumed that deficiencies or enhancements of the lift carry over across the fuselage-shrouded wing are the driving mechanism for departures of wake-segments. The computations presented first indicate that upwardly departing wake segments that were observed and photographed could have been produced by a deficiency in lift carryover across the fuselage-shrouded part of the wing. Computations made of idealized vortex wakes indicate that upward departure of a wake segment requires a centerline reduction in the span loading of 70% or more, whether the engines are at idle or robust thrust. Similarly, it was found that downward departure of wake segments is produced when the lift over the center part of the wing is enhanced. However, it was also found that downward departures do not occur without the presence of robust engine-exhaust streams (i.e., engines must NOT be at idle). In those cases, downward departures of a wake segment occurs when the centerline value of the loading is enhanced by any amount between about 10% to 100%. Observations of condensation trails indicate that downward departure of wake segments is rare. Upward departures of wake segments appears to be more common but still rare. A study to determine the part of the aircraft that causes wake departures has not been carried out. However, even though departures of wake segments rarely occur, some aircraft do regularly shed these wake structures. If aircraft safety is to be assured to a high degree of reliability, and a solution for eliminating them is not implemented, existing guidelines for the avoidance of vortex wakes [1,3] may need to be broadened to include possible increases in wake sizes caused by vertical departures of wake segments. Further study may indicate that it is not possible to modify existing aircraft enough to prevent wake departures. Wake-avoidance guidelines must then be adjusted to provide the desired degree of safety. It appears that steps to avoid upwardly moving wake segments have already been incorporated into the avoidance procedures used for aircraft on approach to runways at the Frankfurt Airport [6,7]. The uncertainty in the prospects for compromises in flight safety caused by rapidly upwardly or downwardly moving wake segments suggest that it be specified that aircraft do not fly above or below each other during operations in the airport vicinity where aircraft are likely to be closely spaced [20].
Stereotypic wheel running decreases cortical activity in mice
Fisher, Simon P.; Cui, Nanyi; McKillop, Laura E.; Gemignani, Jessica; Bannerman, David M.; Oliver, Peter L.; Peirson, Stuart N.; Vyazovskiy, Vladyslav V.
2016-01-01
Prolonged wakefulness is thought to gradually increase ‘sleep need' and influence subsequent sleep duration and intensity, but the role of specific waking behaviours remains unclear. Here we report the effect of voluntary wheel running during wakefulness on neuronal activity in the motor and somatosensory cortex in mice. We find that stereotypic wheel running is associated with a substantial reduction in firing rates among a large subpopulation of cortical neurons, especially at high speeds. Wheel running also has longer-term effects on spiking activity across periods of wakefulness. Specifically, cortical firing rates are significantly higher towards the end of a spontaneous prolonged waking period. However, this increase is abolished when wakefulness is dominated by running wheel activity. These findings indicate that wake-related changes in firing rates are determined not only by wake duration, but also by specific waking behaviours. PMID:27748455
Development of Predictive Wake Vortex Transport Model for Terminal Area Wake Vortex Avoidance
DOT National Transportation Integrated Search
1976-05-01
The wake vortex transport program has been expanded to include viscous effects and the influence of initial roll-up, atmospheric turbulence, and wind shear on the persistence and motion of wake vortices in terminal areas. Analysis of wake characteris...
Spatial Linear Instability of Confluent Wake/Boundary Layers
NASA Technical Reports Server (NTRS)
Liou, William W.; Liu, Feng-Jun; Rumsey, C. L. (Technical Monitor)
2001-01-01
The spatial linear instability of incompressible confluent wake/boundary layers is analyzed. The flow model adopted is a superposition of the Blasius boundary layer and a wake located above the boundary layer. The Orr-Sommerfeld equation is solved using a global numerical method for the resulting eigenvalue problem. The numerical procedure is validated by comparing the present solutions for the instability of the Blasius boundary layer and for the instability of a wake with published results. For the confluent wake/boundary layers, modes associated with the boundary layer and the wake, respectively, are identified. The boundary layer mode is found amplified as the wake approaches the wall. On the other hand, the modes associated with the wake, including a symmetric mode and an antisymmetric mode, are stabilized by the reduced distance between the wall and the wake. An unstable mode switching at low frequency is observed where the antisymmetric mode becomes more unstable than the symmetric mode when the wake velocity defect is high.
NASA Astrophysics Data System (ADS)
Turchak, L. I.
2012-10-01
The objective is the general review of impact of aircraft wake vortices on the follower aircraft encountering the wake. Currently, the presence of wake vortices past aircraft limits the airspace capacity and flight safety level for aircraft of different purposes. However, wake vortex nature and evolution have not been studied in full measure. A mathematical model simulating the process of near wake generation past bodies of different shapes, as well as the wake evolution after rolling-up into wake vortices (far wake) is developed. The processes are suggested to be modeled by means of the Method of Discrete Vortices. Far wake evolution is determined by its complex interaction with the atmosphere and ground boundary layer. The main factors that are supposed to take into account are: wind and ambient turbulence 3Ddistributions, temperature stratification of the atmosphere, wind shear, as well as some others which effects will be manifested as considerable during the investigation. The ground boundary layer effects on wake vortex evolution are substantial at low flight altitudes and are determined through the boundary layer separation.
Zhai, Xiaochun; Wu, Songhua; Liu, Bingyi
2017-06-12
Four field experiments based on Pulsed Coherent Doppler Lidar with different surface roughness have been carried out in 2013-2015 to study the turbulent wind field in the vicinity of operating wind turbine in the onshore and offshore wind parks. The turbulence characteristics in ambient atmosphere and wake area was analyzed using transverse structure function based on Plane Position Indicator scanning mode. An automatic wake processing procedure was developed to determine the wake velocity deficit by considering the effect of ambient velocity disturbance and wake meandering with the mean wind direction. It is found that the turbine wake obviously enhances the atmospheric turbulence mixing, and the difference in the correlation of turbulence parameters under different surface roughness is significant. The dependence of wake parameters including the wake velocity deficit and wake length on wind velocity and turbulence intensity are analyzed and compared with other studies, which validates the empirical model and simulation of a turbine wake for various atmosphere conditions.
BASIC ELECTRICITY. SCIENCE IN ACTION SERIES, NUMBER 14.
ERIC Educational Resources Information Center
CASSEL, RICHARD
THIS TEACHING GUIDE, INVOLVING ACTIVITIES FOR DEVELOPING AN UNDERSTANDING OF BASIC ELECTRICITY, EMPHASIZES STUDENT INVESTIGATIONS RATHER THAN FACTS, AND IS BASED ON THE PREMISE THAT THE MAJOR GOAL IN SCIENCE TEACHING IS THE DEVELOPMENT OF THE INVESTIGATIVE ATTITUDE IN THE STUDENT. ACTIVITIES SUGGESTED INVOLVE SIMPLE DEMONSTRATIONS AND EXPERIMENTS…
Integration of Basic Sciences in Health's Courses
ERIC Educational Resources Information Center
Azzalis, L. A.; Giavarotti, L.; Sato, S. N.; Barros, N. M. T.; Junqueira, V. B. C.; Fonseca, F. L. A.
2012-01-01
Concepts from disciplines such as Biochemistry, Genetics, Cellular and Molecular Biology are essential to the understanding and treatment of an elevated number of illnesses, but often they are studied separately, with no integration between them. This article proposes a model for basic sciences integration based on problem-based learning (PBL) and…
Teaching Toxicology as a Basic Medical Science
ERIC Educational Resources Information Center
Gralla, Edward J.
1976-01-01
A 4-year effort at Yale University School of Medicine to teach toxicology as an elective basic science from the standpoint of organ-specific toxic effects is described. The objective of the successful multidisciplinary program is to prepare physicians to understand, recognize, and manage adverse effects from drugs and other environmental…
ON THE NATURE OF SPEECH SCIENCE.
ERIC Educational Resources Information Center
PETERSON, GORDON E.
IN THIS ARTICLE THE NATURE OF THE DISCIPLINE OF SPEECH SCIENCE IS CONSIDERED AND THE VARIOUS BASIC AND APPLIED AREAS OF THE DISCIPLINE ARE DISCUSSED. THE BASIC AREAS ENCOMPASS THE VARIOUS PROCESSES OF THE PHYSIOLOGY OF SPEECH PRODUCTION, THE ACOUSTICAL CHARACTERISTICS OF SPEECH, INCLUDING THE SPEECH WAVE TYPES AND THE INFORMATION-BEARING ACOUSTIC…
Aeronautical Sciences Advanced Studies Program. Delivery Order 0002: Plasma Modeling Program
2009-04-01
reach the stagnation point of the airfoil. However, the effect is much more pronounced at the trailing edge region of the airfoil and its wake region...presents measured results that provide an indication of the amount of noise in the pitot probe measurements. The second presents the results of...is the noise problems that occurred in the measurements when a magnetic field was applied. For this reason the results with a magnetic field applied
Aircraft Wake Vortices: An Assessment of the Current Situation
1991-01-01
1979 , DOT/TSC, Cambridge, MA. 36. Burnham, D.C., "Chicago Monostatic Acoustic Vortex Sensing System, Vol. I : Data Collection and Reduction," FAA-RD-79...April 1979 , DOT/TSC, Cambridge, MA. 45. Hallock, J.N., "Vortex Advisory System Safety Analysis; Vol. I : Analytical Model," FAA-RD-78-68. I , September...Industry Representatives," March 1979 , Economics & Science Planning Inc., Washington, DC. 106. Hallock, J.N., "Vortex Advisory System, Vol. I : Effectiveness
LEDs Illuminate Bulbs for Better Sleep, Wake Cycles
NASA Technical Reports Server (NTRS)
2015-01-01
Life on the International Space Station (ISS) wreaks havoc on an astronaut’s biological rhythms, and one way NASA mitigates the problem is through the use of LED lighting to alternately stimulate energy and focus and induce relaxation. Satellite Beach, Florida-based Lighting Science partnered with Kennedy Space Center to commercialize an LED system designed for the ISS, resulting in its DefinityDigital product line of light bulbs now used in numerous homes, hotel chains, and resorts.
Zhu, Yan; Fenik, Polina; Zhan, Guanxia; Somach, Rebecca; Xin, Ryan; Veasey, Sigrid
2016-08-01
Intermittent short sleep (ISS) is pervasive among students and workers in modern societies, yet the lasting consequences of repeated short sleep on behavior and brain health are largely unexplored. Wake-activated neurons may be at increased risk of metabolic injury across sustained wakefulness. To examine the effects of ISS on wake-activated neurons and wake behavior, wild-type mice were randomized to ISS (a repeated pattern of short sleep on 3 consecutive days followed by 4 days of recovery sleep for 4 weeks) or rested control conditions. Subsets of both groups were allowed a recovery period consisting of 4-week unperturbed activity in home cages with littermates. Mice were examined for immediate and delayed (following recovery) effects of ISS on wake neuron cell metabolics, cell counts, and sleep/wake patterns. ISS resulted in sustained disruption of sleep/wake activity, with increased wakefulness during the lights-on period and reduced wake bout duration and wake time during the lights-off period. Noradrenergic locus coeruleus (LC) and orexinergic neurons showed persistent alterations in morphology, and reductions in both neuronal stereological cell counts and fronto-cortical projections. Surviving wake-activated neurons evidenced persistent reductions in sirtuins 1 and 3 and increased lipofuscin. In contrast, ISS resulted in no lasting injury to the sleep-activated melanin concentrating hormone neurons. Collectively these findings demonstrate for the first time that ISS imparts significant lasting disturbances in sleep/wake activity, degeneration of wake-activated LC and orexinergic neurons, and lasting metabolic changes in remaining neurons most consistent with premature senescence. © 2016 Associated Professional Sleep Societies, LLC.
Consciousness, brain, neuroplasticity
Askenasy, Jean; Lehmann, Joseph
2013-01-01
Subjectivity, intentionality, self-awareness and will are major components of consciousness in human beings. Changes in consciousness and its content following different brain processes and malfunction have long been studied. Cognitive sciences assume that brain activities have an infrastructure, but there is also evidence that consciousness itself may change this infrastructure. The two-way influence between brain and consciousness has been at the center of philosophy and less so, of science. This so-called bottom-up and top-down interrelationship is controversial and is the subject of our article. We would like to ask: how does it happen that consciousness may provoke structural changes in the brain? The living brain means continuous changes at the synaptic level with every new experience, with every new process of learning, memorizing or mastering new and existing skills. Synapses are generated and dissolved, while others are preserved, in an ever-changing process of so-called neuroplasticity. Ongoing processes of synaptic reinforcements and decay occur during wakefulness when consciousness is present, but also during sleep when it is mostly absent. We suggest that consciousness influences brain neuroplasticity both during wakefulness as well as sleep in a top-down way. This means that consciousness really activates synaptic flow and changes brain structures and functional organization. The dynamic impact of consciousness on brain never stops despite the relative stationary structure of the brain. Such a process can be a target for medical intervention, e.g., by cognitive training. PMID:23847580
Patel, Mainak; Rangan, Aaditya
2017-08-07
Infant rats randomly cycle between the sleeping and waking states, which are tightly correlated with the activity of mutually inhibitory brainstem sleep and wake populations. Bouts of sleep and wakefulness are random; from P2-P10, sleep and wake bout lengths are exponentially distributed with increasing means, while during P10-P21, the sleep bout distribution remains exponential while the distribution of wake bouts gradually transforms to power law. The locus coeruleus (LC), via an undeciphered interaction with sleep and wake populations, has been shown experimentally to be responsible for the exponential to power law transition. Concurrently during P10-P21, the LC undergoes striking physiological changes - the LC exhibits strong global 0.3 Hz oscillations up to P10, but the oscillation frequency gradually rises and synchrony diminishes from P10-P21, with oscillations and synchrony vanishing at P21 and beyond. In this work, we construct a biologically plausible Wilson Cowan-style model consisting of the LC along with sleep and wake populations. We show that external noise and strong reciprocal inhibition can lead to switching between sleep and wake populations and exponentially distributed sleep and wake bout durations as during P2-P10, with the parameters of inhibition between the sleep and wake populations controlling mean bout lengths. Furthermore, we show that the changing physiology of the LC from P10-P21, coupled with reciprocal excitation between the LC and wake population, can explain the shift from exponential to power law of the wake bout distribution. To our knowledge, this is the first study that proposes a plausible biological mechanism, which incorporates the known changing physiology of the LC, for tying the developing sleep-wake circuit and its interaction with the LC to the transformation of sleep and wake bout dynamics from P2-P21. Copyright © 2017 Elsevier Ltd. All rights reserved.
Using the earth system for integrating the science curriculum
NASA Astrophysics Data System (ADS)
Mayer, Victor J.
Content and process instruction from the earth sciences has gone unrepresented in the world's science curricula, especially at the secondary level. As a result there is a serious deficiency in public understanding of the planet on which we all live. This lack includes national and international leaders in politics, business, and science. The earth system science effort now engaging the research talent of the earth sciences provides a firm foundation from the sciences for inclusion of earth systems content into the evolving integrated science curricula of this country and others. Implementing integrated science curricula, especially at the secondary level where potential leaders often have their only exposure to science, can help to address these problems. The earth system provides a conceptual theme as opposed to a disciplinary theme for organizing such integrated curricula, absent from prior efforts. The end of the cold war era is resulting in a reexamination of science and the influence it has had on our planet and society. In the future, science and the curricula that teach about science must seriously address the environmental and social problems left in the wake of over 100 years of preparation for military and economic war. The earth systems education effort provides one such approach to the modernization of science curricula. Earth science educators should assume leadership in helping to establish such curricula in this country and around the world.
Stephen F. McCool; David N. Cole; William T. Borrie; Jennifer O' Loughlin
2000-01-01
Thirty-six papers related to the theme of wilderness as a place to conduct science are included. Five overview papers synthesize knowledge and research about basic work in the biophysical and social sciences that has been conducted in wilderness. Other papers present the results of focused basic research in wilderness, with one set of papers devoted to the conduct and...
The Stability Region for Feedback Control of the Wake Behind Twin Oscillating Cylinders
NASA Astrophysics Data System (ADS)
Borggaard, Jeff; Gugercin, Serkan; Zietsman, Lizette
2016-11-01
Linear feedback control has the ability to stabilize vortex shedding behind twin cylinders where cylinder rotation is the actuation mechanism. Complete elimination of the wake is only possible for certain Reynolds numbers and cylinder spacing. This is related to the presence of asymmetric unstable modes in the linearized system. We investigate this region of parameter space using a number of closed-loop simulations that bound this region. We then consider the practical issue of designing feedback controls based on limited state measurements by building a nonlinear compensator using linear robust control theory with and incorporating the nonlinear terms in the compensator (e.g., using the extended Kalman filter). Interpolatory model reduction methods are applied to the large discretized, linearized Navier-Stokes system and used for computing the control laws and compensators. Preliminary closed-loop simulations of a three-dimensional version of this problem will also be presented. Supported in part by the National Science Foundation.
Trains of electron micro-bunches in plasma wake-field acceleration
NASA Astrophysics Data System (ADS)
Lécz, Zsolt; Andreev, Alexander; Konoplev, Ivan; Seryi, Andrei; Smith, Jonathan
2018-07-01
Plasma-based charged particle accelerators have been intensively investigated in the past three decades due to their capability to open up new horizons in accelerator science and particle physics yielding electric field accelerating gradient more than three orders of magnitudes higher than in conventional devices. At the current stage the most advanced and reliable mechanism for accelerating electrons is based on the propagation of an intense laser pulse or a relativistic electron beam in a low density gaseous target. In this paper we concentrate on the electron beam-driven plasma wake-field acceleration and demonstrate using 3D PiC simulations that a train of electron micro-bunches with ∼10 fs period can be generated behind the driving beam propagating in a density down-ramp. We will discuss the conditions and properties of the micro-bunches generated aiming at understanding and study of multi-bunch mechanism of injection. It is show that the periodicity and duration of micro-bunches can be controlled by adjusting the plasma density gradient and driving beam charge.
Report on final recommendations for IMPS engineering-science payload
NASA Technical Reports Server (NTRS)
Garrett, H. B.
1984-01-01
Six general categories of key scientific and engineering concerns for the interactions measurements payload for shuttle (IMPS) mission are addressed: (1) dielectric charging; (2) material property changes; (3) electromagnetic interference, plasma interactions, and plasma wake effects associated with high-voltage solar arrays and large space structures; (4) radio frequency distortion and nonlinearities due to the enhanced plasma in the shuttle ram/wake; (5) shuttle glow and contamination; and (6) plasma interactions with the space-based radar. Lesser concerns are the interactions associated with EVA; the radiation and SEU effects peculiar to the auroral/polar cap environments; and space debris. The measurements needed to address the concerns associated with the general categories are described and a list of generic investigations capable of making the required measurements, emphasizing the spectrum of measurements necessary to quantize the interactions in the auroral/polar environments are included. A suggested ground-test plan for the IMPS project, a description of proposed follow-on IMPS missions, and a detailed bibliography for each of the interactions discussed are included.
NASA Astrophysics Data System (ADS)
Qin, Haiyun; Zhao, Wei; Zhang, Chen; Liu, Yong; Wang, Guiren; Wang, Kaige
2018-03-01
Not Available Project supported by the National Natural Science Foundation of China (Grant Nos. 11672229 and 61378083), International Cooperation Foundation of the National Science and Technology Major Project of the Ministry of Science and Technology of China (Grant No. 2011DFA12220), Major Research Plan of the National Natural Science Foundation of China (Grant No. 91123030), Natural Science Foundation of Shaanxi Province of China (Grant Nos. 2010JS110 and 2013SZS03-Z01), Natural Science Basic Research Program of Shaanxi Province — Major Basic Research Project, China (Grant No. 2016ZDJC-15), Young Scientist Fund of the National Natural Science Foundation of China (Grant No. 11504294), and the Youth Talent Plan of the Natural Science Foundation of Shaanxi Province of China (Grant No. 2016JQ103).
Flight Data Reduction of Wake Velocity Measurements Using an Instrumented OV-10 Airplane
NASA Technical Reports Server (NTRS)
Vicroy, Dan D.; Stuever, Robert A.; Stewart, Eric C.; Rivers, Robert A.
1999-01-01
A series of flight tests to measure the wake of a Lockheed C- 130 airplane and the accompanying atmospheric state have been conducted. A specially instrumented North American Rockwell OV-10 airplane was used to measure the wake and atmospheric conditions. An integrated database has been compiled for wake characterization and validation of wake vortex computational models. This paper describes the wake- measurement flight-data reduction process.
Tracking and Characterization of Aircraft Wakes Using Acoustic and Lidar Measurements
NASA Technical Reports Server (NTRS)
Booth, Earl R., Jr.; Humphreys, William M., Jr.
2005-01-01
Data from the 2003 Denver International Airport Wake Acoustics Test are further examined to discern spectral content of aircraft wake signatures, and to compare three dimensional wake tracking from acoustic data to wake tracking data obtained through use of continuous wave and pulsed lidar. Wake tracking data derived from acoustic array data agree well with both continuous wave and pulsed lidar in the horizontal plane, but less well with pulsed lidar in the vertical direction. Results from this study show that the spectral distribution of acoustic energy in a wake signature varies greatly with aircraft type.
Cosmic string wakes and large-scale structure
NASA Technical Reports Server (NTRS)
Charlton, Jane C.
1988-01-01
The formation of structure from infinite cosmic string wakes is modeled for a universe dominated by cold dark matter (CDM). Cross-sectional slices through the wake distribution tend to outline empty regions with diameters which are not inconsistent with the range of sizes of the voids in the CfA slice of the universe. The topology of the wake distribution is found to be spongy rather than cell-like. Correlations between CDM wakes do not extend much beyond a horizon length, so it is unlikely that CDM wakes are responsible for the correlations between clusters of galaxies. An estimate of the fraction of matter to accrete onto CDM wakes indicates that wakes could be more important in galaxy formation than previously anticipated.
Wind Turbine Wake-Redirection Control at the Fishermen's Atlantic City Windfarm: Preprint
DOE Office of Scientific and Technical Information (OSTI.GOV)
Churchfield, M.; Fleming, P.; Bulder, B.
2015-05-06
In this paper, we will present our work towards designing a control strategy to mitigate wind turbine wake effects by redirecting the wakes, specifically applied to the Fishermen’s Atlantic City Windfarm (FACW), proposed for deployment off the shore of Atlantic City, New Jersey. As wind turbines extract energy from the air, they create low-speed wakes that extend behind them. Full wake recovery Full wake recovery to the undisturbed wind speed takes a significant distance. In a wind energy plant the wakes of upstream turbines may travel downstream to the next row of turbines, effectively subjecting them to lower wind speeds,more » meaning these waked turbines will produce less power.« less
Wake Vortex Advisory System (WakeVAS) Concept of Operations
NASA Technical Reports Server (NTRS)
Rutishauser, David; Lohr, Gary; Hamilton, David; Powers, Robert; McKissick, Burnell; Adams, Catherine; Norris, Edward
2003-01-01
NASA Langley Research Center has a long history of aircraft wake vortex research, with the most recent accomplishment of demonstrating the Aircraft VOrtex Spacing System (AVOSS) at Dallas/Forth Worth International Airport in July 2000. The AVOSS was a concept for an integration of technologies applied to providing dynamic wake-safe reduced spacing for single runway arrivals, as compared to current separation standards applied during instrument approaches. AVOSS included state-of-the-art weather sensors, wake sensors, and a wake behavior prediction algorithm. Using real-time data AVOSS averaged a 6% potential throughput increase over current standards. This report describes a Concept of Operations for applying the technologies demonstrated in the AVOSS to a variety of terminal operations to mitigate wake vortex capacity constraints. A discussion of the technological issues and open research questions that must be addressed to design a Wake Vortex Advisory System (WakeVAS) is included.
NASA Technical Reports Server (NTRS)
Stebbins, Albert; Veeraraghavan, Shoba; Silk, Joseph; Brandenberger, Robert; Turok, Neil
1987-01-01
Accretion of matter onto wakes left behind by horizon-sized pieces of cosmic string is investigated, and the effects of wakes on the large-scale structure of the universe are determined. Accretion of cold matter onto wakes, the effects of a long string on fluids with finite velocity dispersion or sound speeds, the interactions between loops and wakes, and the conditions for wakes to survive disruption by loops are discussed. It is concluded that the most important wakes are those which were formed at the time of equal matter and radiation density. This leads to sheetlike overdense regions of galaxies with a mean separation in agreement with the scale of the bubbles of de Lapparent, Geller, and Huchra (1986). However, for the value of G(mu) favored from galaxy formation considerations in a universe with cold dark matter, a wake accretes matter from a distance of only about 1.5 Mpc, which is much less than the distance between the wakes.
Solar-wind proton access deep into the near-Moon wake
NASA Astrophysics Data System (ADS)
Nishino, M. N.; Fujimoto, M.; Maezawa, K.; Saito, Y.; Yokota, S.; Asamura, K.; Tanaka, T.; Tsunakawa, H.; Matsushima, M.; Takahashi, F.; Terasawa, T.; Shibuya, H.; Shimizu, H.
2009-08-01
We study solar wind (SW) entry deep into the near-Moon wake using SELENE (KAGUYA) data. It has been known that SW protons flowing around the Moon access the central region of the distant lunar wake, while their intrusion deep into the near-Moon wake has never been expected. We show that SW protons sneak into the deepest lunar wake (anti-subsolar region at ˜100 km altitude), and that the entry yields strong asymmetry of the near-Moon wake environment. Particle trajectory calculations demonstrate that these SW protons are once scattered at the lunar dayside surface, picked-up by the SW motional electric field, and finally sneak into the deepest wake. Our results mean that the SW protons scattered at the lunar dayside surface and coming into the night side region are crucial for plasma environment in the wake, suggesting absorption of ambient SW electrons into the wake to maintain quasi-neutrality.
Simulated Wake Characteristics Data for Closely Spaced Parallel Runway Operations Analysis
NASA Technical Reports Server (NTRS)
Guerreiro, Nelson M.; Neitzke, Kurt W.
2012-01-01
A simulation experiment was performed to generate and compile wake characteristics data relevant to the evaluation and feasibility analysis of closely spaced parallel runway (CSPR) operational concepts. While the experiment in this work is not tailored to any particular operational concept, the generated data applies to the broader class of CSPR concepts, where a trailing aircraft on a CSPR approach is required to stay ahead of the wake vortices generated by a lead aircraft on an adjacent CSPR. Data for wake age, circulation strength, and wake altitude change, at various lateral offset distances from the wake-generating lead aircraft approach path were compiled for a set of nine aircraft spanning the full range of FAA and ICAO wake classifications. A total of 54 scenarios were simulated to generate data related to key parameters that determine wake behavior. Of particular interest are wake age characteristics that can be used to evaluate both time- and distance- based in-trail separation concepts for all aircraft wake-class combinations. A simple first-order difference model was developed to enable the computation of wake parameter estimates for aircraft models having weight, wingspan and speed characteristics similar to those of the nine aircraft modeled in this work.
Forecasting Behavior in Smart Homes Based on Sleep and Wake Patterns
Williams, Jennifer A.; Cook, Diane J.
2017-01-01
Background The goal of this research is to use smart home technology to assist people who are recovering from injuries or coping with disabilities to live independently. Objective We introduce an algorithm to model and forecast wake and sleep behaviors that are exhibited by the participant. Furthermore, we propose that sleep behavior is impacted by and can be modeled from wake behavior, and vice versa. Methods This paper describes the Behavior Forecasting (BF) algorithm. BF consists of 1) defining numeric values that reflect sleep and wake behavior, 2) forecasting wake and sleep values from past behavior, 3) analyzing the effect of wake behavior on sleep and vice versa, and 4) improving prediction performance by using both wake and sleep scores. Results The BF method was evaluated with data collected from 20 smart homes. We found that regardless of the forecasting method utilized, wake behavior and sleep behavior can be modeled with a minimum accuracy of 84%. Additionally, normalizing the wake and sleep scores drastically improves the accuracy to 99%. Conclusions The results show that we can effectively model wake and sleep behaviors in a smart environment. Furthermore, wake behaviors can be predicted from sleep behaviors and vice versa. PMID:27689555
Forecasting behavior in smart homes based on sleep and wake patterns.
Williams, Jennifer A; Cook, Diane J
2017-01-01
The goal of this research is to use smart home technology to assist people who are recovering from injuries or coping with disabilities to live independently. We introduce an algorithm to model and forecast wake and sleep behaviors that are exhibited by the participant. Furthermore, we propose that sleep behavior is impacted by and can be modeled from wake behavior, and vice versa. This paper describes the Behavior Forecasting (BF) algorithm. BF consists of 1) defining numeric values that reflect sleep and wake behavior, 2) forecasting wake and sleep values from past behavior, 3) analyzing the effect of wake behavior on sleep and vice versa, and 4) improving prediction performance by using both wake and sleep scores. The BF method was evaluated with data collected from 20 smart homes. We found that regardless of the forecasting method utilized, wake behavior and sleep behavior can be modeled with a minimum accuracy of 84%. Additionally, normalizing the wake and sleep scores drastically improves the accuracy to 99%. The results show that we can effectively model wake and sleep behaviors in a smart environment. Furthermore, wake behaviors can be predicted from sleep behaviors and vice versa.
Effect of nacelle on wake meandering in a laboratory scale wind turbine using LES
NASA Astrophysics Data System (ADS)
Foti, Daniel; Yang, Xiaolei; Guala, Michele; Sotiropoulos, Fotis
2015-11-01
Wake meandering, large scale motion in the wind turbine wakes, has considerable effects on the velocity deficit and turbulence intensity in the turbine wake from the laboratory scale to utility scale wind turbines. In the dynamic wake meandering model, the wake meandering is assumed to be caused by large-scale atmospheric turbulence. On the other hand, Kang et al. (J. Fluid Mech., 2014) demonstrated that the nacelle geometry has a significant effect on the wake meandering of a hydrokinetic turbine, through the interaction of the inner wake of the nacelle vortex with the outer wake of the tip vortices. In this work, the significance of the nacelle on the wake meandering of a miniature wind turbine previously used in experiments (Howard et al., Phys. Fluid, 2015) is demonstrated with large eddy simulations (LES) using immersed boundary method with fine enough grids to resolve the turbine geometric characteristics. The three dimensionality of the wake meandering is analyzed in detail through turbulent spectra and meander reconstruction. The computed flow fields exhibit wake dynamics similar to those observed in the wind tunnel experiments and are analyzed to shed new light into the role of the energetic nacelle vortex on wake meandering. This work was supported by Department of Energy DOE (DE-EE0002980, DE-EE0005482 and DE-AC04-94AL85000), and Sandia National Laboratories. Computational resources were provided by Sandia National Laboratories and the University of Minnesota Supercomputing.
NASA Technical Reports Server (NTRS)
Roberts, Chistopher L.
2001-01-01
Aircraft travel has become a major form of transportation. Several of our major airports are operating near their capacity limit, increasing congestion and delays for travelers. As a result, the National Aeronautics and Space Administration (NASA) has been working in conjunction with the Federal Aviation Administration (FAA), airline operators, and the airline industry to increase airport capacity without sacrificing public safety. One solution to the problem is to increase the number of airports and build new. runways; yet, this solution is becoming increasingly difficult due to limited space. A better solution is to increase the production per runway. This solution increases the possibility that one aircraft will encounter the trailing wake of another aircraft. Hazardous wake vortex encounters occur when an aircraft encounters the wake produced by a heavier aircraft. This heavy-load aircraft produces high-intensity wake turbulence that redistributes the aerodynamic loads of trailing smaller aircraft. This situation is particularly hazardous for smaller aircraft during takeoffs and landings. In order to gain a better understanding of the wake-vortex/aircraft encounter phenomena, NASA Langley Research Center conducted a series of flight tests from 1995 through 1997. These tests were designed to gather data for the development a wake encounter and wake-measurement data set with the accompanying atmospheric state information. This data set is being compiled into a database that can be used by wake vortex researchers to compare with experimental and computational results. The purpose of this research is to derive and implement a procedure for calculating the wake-vortex/aircraft interaction portion of that database by using the data recorded during those flight tests. There were three objectives to this research. Initially, the wake-induced forces and moments from each flight were analyzed based on varying flap deflection angles. The flap setting alternated between 15 and 30 degrees while the separation distance remained constant. This examination was performed to determine if increases in flap deflection would increase or decrease the effects of the wake-induced forces and moments. Next, the wake-induced forces and moments from each flight were analyzed based on separation distances of 1-3 nautical miles. In this comparison, flap deflection was held constant at 30 degrees. The purpose of this study was to determine if increased separation distances reduced the effects of the wake vortex on the aircraft. The last objective compared the wake-induced forces and moments of each flight as it executed a series of maneuvers through the wake-vortex. This analysis was conducted to examine the impact of the wake on the B737 as it traversed the wake horizontally and vertically. Results from the first analysis indicated that there was no difference in wake effect at flap deflections of 15 and 30 degrees. This conclusion is evidenced in the cases of the wake-induced sideforce, rolling moment, and yawing moment. The wake-induced lift, drag, and pitching moment cases yielded less conclusive results. The second analysis compared the wake-induced forces and moments at separation distances of 1-3 nautical miles. Results indicated that there was no significant difference in the wake-induced lift, drag, sideforce, or yawing moment coefficients. The analysis compared the wake-induced forces and moments based on different flight maneuvers. It was found that the wake-induced forces and moments had the greatest impact on out-to-in and in-to-out maneuvers.
Respiratory pathophysiology: sleep-related breathing disorders
Schäfer, Thorsten
2006-01-01
A widespread network of respiratory-related neurons within the brainstem controls the regular respiratory cycle, which is dependent upon unspecific and specific drives like hypoxia or hypercapnia. This respiratory network and its respiratory drives are subjects to typical changes during the transition from wakefulness to sleep and within the various sleep states, which favor a destabilization of breathing during sleep. There is also a respiratory-related innervation of the dilating and stiffening pharyngeal muscles as well as a local reflex control of the basic tone of upper airway muscles, both of which are influenced by the different states of wakefulness and sleep. These sleep-related changes cause an increase in upper airway resistance during sleep. In healthy subjects, however, these features during sleep are almost completely compensated and the gas exchange is hardly hindered. However, in the case of illness, severe disordered breathing, disturbed gas exchange and interrupted sleep may occur. The central hypoventilation syndrome, central apnea-hypopnea syndromes, as well as the obstructive sleep apnea syndrome belong to these diseases. Because of the intense research, we have a detailed picture of the pathophysiological mechanisms of the origin and the maintenance of sleep-related breathing disorders. PMID:22073070
NASA Astrophysics Data System (ADS)
Gertsch, L. S.; Morris, K. A.
2017-02-01
The sustainable exploration of space requires in situ resource utilization (ISRU). Successful ISRU depends on a solid science foundation; consequently, planetary science must include basic and applied science investigations to support ISRU.
Direct Simulation and Theoretical Study of Sub- and Supersonic Wakes
NASA Astrophysics Data System (ADS)
Hickey, Jean-Pierre
Wakes are constitutive components of engineering, aeronautical and geophysical flows. Despite their canonical nature, many fundamental questions surrounding wakes remain unanswered. The present work studies the nature of archetypal planar splitter-plate wakes in the sub- and supersonic regimes from a theoretical as well as a numerical perspective. A highly-parallelizable computational fluid dynamic solver was developed, from scratch, for the very-large scale direct numerical simulations of high-speed free shear flows. Wakes maintain a near indelible memory of their origins; thus, changes to the state of the flow on the generating body lead to multiple self-similar states in the far wake. To understand the source of the lack of universality, three distinct wake evolution scenarios are investigated in the incompressible limit: the Kelvin-Helmholtz transition, the bypass transition in an asymmetric wake and the initially turbulent wake. The multiplicity of self-similar states is the result of a plurality of far wake structural organizations, which maintains the memory of the flow. The structural organization is predicated on the presence or absence of near wake anti-symmetric perturbations (as a result of shedding, instability modes and/or trailing edge receptivity). The plurality of large-scale structural organization contrasts with the commonality observed in the mid-sized structures, which are dominated by inclined vortical rods, and not, as previously assumed, by horseshoe structures. The compressibility effects are a direct function of the maximal velocity defect in the wake and are therefore only important in the transitional region - the far wake having an essentially incompressible character. The compressibility simultaneously modifies the growth rate and wavelength of the primary instability mode with a concomitant effect on the emerging transitional structures. As a direct result, the spanwise rollers have an increasing ellipticity and cross-wake domain of influence with the increasing Mach number of the wake. Consequently, structural pairing - a key feature of wake transition - is inhibited at a critical Mach number, which greatly modifies the transitional dynamics. In idealized wakes, the increased stability caused by the compressibility effects leads to a vortex breakdown of secondary structures prior to the full transition of the principal mode. These findings open the door to novel mixing enhancement and flow control possibilities in the high-speed wake transition. Keywords: FLUID DYNAMICS, DIRECT NUMERICAL SIMULATIONS, FREE SHEAR FLOWS, TURBULENCE, NUMERICAL METHODS
NASA Astrophysics Data System (ADS)
Taniai, Tetsuyuki; Sugimoto, Taku; Sato, Ken-Ichi; Ikota, Masaru
The Education Center of Chiba Institute of Technology is taking a new approach to the introduction of liberal arts subjects commonly included in the curriculum of all departments through a newly established basic seminar, the Science of Snow Sports. Each faculty member has been working on setting up classes that cross the conventional boundaries of fields and disciplines and which are targeted at students of all faculties and departments. This paper describes the potential for teaching liberal arts and social science subjects to engineering students through the medium of sports science, based on actual experience gained via this new approach.
Ship wakes and their manifestations on the sea surface
NASA Astrophysics Data System (ADS)
Ermakov, Stanislav; Kapustin, Ivan; Kalimulin, Rashid
2013-04-01
Spatial/temporal evolution of turbulence generated by surface ships and the effect of the wake on short wind waves has been studied on the Black Sea and on the Gorky Water Reservoir. Measurements of currents in ship wakes were conducted using an Acoustic Doppler Current Profiler deployed from a motor boat. It was obtained that the temporal/spatial evolution of the wake width could be described approximately by a 0.4-power dependence, and the wake depth remained nearly constant at its initial stage. This allowed one to consider the wake widening as a one-dimensional process. We have developed a simple one-dimensional model of ship wake evolution using a semi-empirical theory of turbulence, and the initial stage of the wake widening (when neglecting dissipation) was described by the equation of turbulent energy balance with the pulse initial condition. Mean circulating currents in the wake zone resulting in the wind wave intensification ("suloi" areas) at the boundaries of the wake were detected in experiment. The asymmetry of the "suloi" bands was observed when the wind was blowing nearly perpendicular to the wake axis. It was shown that the later stage of the wake evolution is characterized by the formation of slick bands at the edges of the wake. The slick bands is a result of the transport of surfactants to the water surface by air bubbles in the wake and their compression due to the mean circulating currents. The work was supported by RFBR (projects 12-05-31237, 11-05-00295), the Program RAN Radiophysics, and by the Russian Government (Grants No. 11.G34.31.0048 and 11.G34.31.0078).
Gonzalo, Jed D; Haidet, Paul; Papp, Klara K; Wolpaw, Daniel R; Moser, Eileen; Wittenstein, Robin D; Wolpaw, Terry
2017-01-01
In the face of a fragmented and poorly performing health care delivery system, medical education in the United States is poised for disruption. Despite broad-based recommendations to better align physician training with societal needs, adaptive change has been slow. Traditionally, medical education has focused on the basic and clinical sciences, largely removed from the newer systems sciences such as population health, policy, financing, health care delivery, and teamwork. In this article, authors examine the current state of medical education with respect to systems sciences and propose a new framework for educating physicians in adapting to and practicing in systems-based environments. Specifically, the authors propose an educational shift from a two-pillar framework to a three-pillar framework where basic, clinical, and systems sciences are interdependent. In this new three-pillar framework, students not only learn the interconnectivity in the basic, clinical, and systems sciences but also uncover relevance and meaning in their education through authentic, value-added, and patient-centered roles as navigators within the health care system. Authors describe the Systems Navigation Curriculum, currently implemented for all students at the Penn State College of Medicine, as an example of this three-pillar educational model. Simple adjustments, such as including occasional systems topics in medical curriculum, will not foster graduates prepared to practice in the 21st-century health care system. Adequate preparation requires an explicit focus on the systems sciences as a vital and equal component of physician education.
An Aeroelastic Perspective of Floating Offshore Wind Turbine Wake Formation and Instability
NASA Astrophysics Data System (ADS)
Rodriguez, Steven N.; Jaworski, Justin W.
2015-11-01
The wake formation and wake stability of floating offshore wind turbines are investigated from an aeroelastic perspective. The aeroelastic model is composed of the Sebastian-Lackner free-vortex wake aerodynamic model coupled to the nonlinear Hodges-Dowell beam equations, which are extended to include the effects of blade profile asymmetry, higher-order torsional effects, and kinetic energy components associated with periodic rigid-body motions of floating platforms. Rigid-body platform motions are also assigned to the aerodynamic model as varying inflow conditions to emulate operational rotor-wake interactions. Careful attention is given to the wake formation within operational states where the ratio of inflow velocity to induced velocity is over 50%. These states are most susceptible to aerodynamic instabilities, and provide a range of states about which a wake stability analysis can be performed. In addition, the stability analysis used for the numerical framework is implemented into a standalone free-vortex wake aerodynamic model. Both aeroelastic and standalone aerodynamic results are compared to evaluate the level of impact that flexible blades have on the wake formation and wake stability.
A roadmap for bridging basic and applied research in forensic entomology.
Tomberlin, J K; Mohr, R; Benbow, M E; Tarone, A M; VanLaerhoven, S
2011-01-01
The National Research Council issued a report in 2009 that heavily criticized the forensic sciences. The report made several recommendations that if addressed would allow the forensic sciences to develop a stronger scientific foundation. We suggest a roadmap for decomposition ecology and forensic entomology hinging on a framework built on basic research concepts in ecology, evolution, and genetics. Unifying both basic and applied research fields under a common umbrella of terminology and structure would facilitate communication in the field and the production of scientific results. It would also help to identify novel research areas leading to a better understanding of principal underpinnings governing ecosystem structure, function, and evolution while increasing the accuracy of and ability to interpret entomological evidence collected from crime scenes. By following the proposed roadmap, a bridge can be built between basic and applied decomposition ecology research, culminating in science that could withstand the rigors of emerging legal and cultural expectations.
Anatomy Integration Blueprint: A Fourth-Year Musculoskeletal Anatomy Elective Model
ERIC Educational Resources Information Center
Lazarus, Michelle D.; Kauffman, Gordon L., Jr.; Kothari, Milind J.; Mosher, Timothy J.; Silvis, Matthew L.; Wawrzyniak, John R.; Anderson, Daniel T.; Black, Kevin P.
2014-01-01
Current undergraduate medical school curricular trends focus on both vertical integration of clinical knowledge into the traditionally basic science-dedicated curricula and increasing basic science education in the clinical years. This latter type of integration is more difficult and less reported on than the former. Here, we present an outline of…
Improving College Faculty Instruction in the Basic and Allied Health Sciences.
ERIC Educational Resources Information Center
Washton, Nathan S.
A project to improve college instruction in the basic and allied health sciences at New York Chiropractic College and the New York Institute of Technology is described. Attention was directed to: the kinds of resources colleges and professional schools provide to improve instruction; motivation of faculty to explore innovative or strategic…
Pair Comparison Study of the Relevance of Nine Basic Science Courses
ERIC Educational Resources Information Center
Spilman, Edra L.; Spilman, Helen W.
1975-01-01
Reports a survey study in which basic science courses were rated according to relevance. Notes approaches for making the anatomy disciplines more relevant because results showed them of lowest relevancy compared with physiology, pathology, and pharmacology which were rated of highest relevance and with biochemistry and microbiology which fell…
A Human Dissection Training Program at Indiana University School of Medicine-Northwest
ERIC Educational Resources Information Center
Talarico, Ernest F., Jr.
2010-01-01
As human cadavers are widely used in basic sciences, medical education, and other training and research venues, there is a real need for experts trained in anatomy and dissection. This article describes a program that gives individuals interested in clinical and basic sciences practical experience working with cadavers. Participants are selected…
An Inexpensive Predictor of Student Performance on Licensure Examinations.
ERIC Educational Resources Information Center
Hyde, R. M.; And Others
1987-01-01
The construction of a comprehensive final examination over the basic medical sciences is described. Performance on the exam was a better predictor of NBME-I scores than GPA in basic science or MCAT scores and a better predictor of NBME-II scores than preclinical course performance and MCAT scores. (Author/RH)
Pima College Students' Knowledge of Selected Basic Physical Science Concepts.
ERIC Educational Resources Information Center
Iadevaia, David G.
In 1989 a study was conducted at Pima Community College (PCC) to assess students' knowledge of basic physical science concepts. A three-part survey instrument was administered to students in a second semester sociology class, a first semester astronomy class, a second semester Spanish class, and a first semester physics class. The survey…
The Sequencing of Basic Chemistry Topics by Physical Science Teachers
ERIC Educational Resources Information Center
Sibanda, Doras; Hobden, Paul
2016-01-01
The purpose of this study was to find out teachers' preferred teaching sequence for basic chemistry topics in Physical Science in South Africa, to obtain their reasons underpinning their preferred sequence, and to compare these sequences with the prescribed sequences in the current curriculum. The study was located within a pragmatic paradigm and…
Medical Student Use of Objectives in Basic Science and Clinical Instruction.
ERIC Educational Resources Information Center
And Others; Mast, Terrill A.
1980-01-01
A study that investigated the long-term use of instructional objectives by medical students taking basic science and clinical courses is reported. Focus is on the extent and manner in which the objectives were used and factors that influenced their use. Students reported heavier usage earlier in the curriculum. (Author/JMD)
Zhu, Yan; Fenik, Polina; Zhan, Guanxia; Somach, Rebecca; Xin, Ryan; Veasey, Sigrid
2016-01-01
Study Objectives: Intermittent short sleep (ISS) is pervasive among students and workers in modern societies, yet the lasting consequences of repeated short sleep on behavior and brain health are largely unexplored. Wake-activated neurons may be at increased risk of metabolic injury across sustained wakefulness. Methods: To examine the effects of ISS on wake-activated neurons and wake behavior, wild-type mice were randomized to ISS (a repeated pattern of short sleep on 3 consecutive days followed by 4 days of recovery sleep for 4 weeks) or rested control conditions. Subsets of both groups were allowed a recovery period consisting of 4-week unperturbed activity in home cages with littermates. Mice were examined for immediate and delayed (following recovery) effects of ISS on wake neuron cell metabolics, cell counts, and sleep/wake patterns. Results: ISS resulted in sustained disruption of sleep/wake activity, with increased wakefulness during the lights-on period and reduced wake bout duration and wake time during the lights-off period. Noradrenergic locus coeruleus (LC) and orexinergic neurons showed persistent alterations in morphology, and reductions in both neuronal stereological cell counts and fronto-cortical projections. Surviving wake-activated neurons evidenced persistent reductions in sirtuins 1 and 3 and increased lipofuscin. In contrast, ISS resulted in no lasting injury to the sleep-activated melanin concentrating hormone neurons. Conclusions: Collectively these findings demonstrate for the first time that ISS imparts significant lasting disturbances in sleep/wake activity, degeneration of wake-activated LC and orexinergic neurons, and lasting metabolic changes in remaining neurons most consistent with premature senescence. Citation: Zhu Y, Fenik P, Zhan G, Somach R, Xin R, Veasey S. Intermittent short sleep results in lasting sleep wake disturbances and degeneration of locus coeruleus and orexinergic neurons. SLEEP 2016;39(8):1601–1611. PMID:27306266
Sleep-Wake Concordance in Couples Is Inversely Associated With Cardiovascular Disease Risk Markers.
Gunn, Heather E; Buysse, Daniel J; Matthews, Karen A; Kline, Christopher E; Cribbet, Matthew R; Troxel, Wendy M
2017-01-01
To determine whether interdependence in couples' sleep (sleep-wake concordance i.e., whether couples are awake or asleep at the same time throughout the night) is associated with two markers of cardiovascular disease (CVD) risk, ambulatory blood pressure (BP) and systemic inflammation. This community-based study is a cross-sectional analysis of 46 adult couples, aged 18-45 years, without known sleep disorders. Percent sleep-wake concordance, the independent variable, was calculated for each individual using actigraphy. Ambulatory BP monitors measured BP across 48 h. Dependent variables included mean sleep systolic BP (SBP) and diastolic BP (DBP), mean wake SBP and DBP, sleep-wake SBP and DBP ratios, and C-reactive protein (CRP). Mixed models were used and were adjusted for age, sex, education, race, and body mass index. Higher sleep-wake concordance was associated with lower sleep SBP (b = -.35, SE = .01) and DBP (b = -.22, SE = .10) and lower wake SBP (b = -.26, SE = .12; all p values < .05). Results were moderated by sex; for women, high concordance was associated with lower BP. Men and women with higher sleep-wake concordance also had lower CRP values (b = -.15, SE = .03, p < .05). Sleep-wake concordance was not associated with wake DBP or sleep/wake BP ratios. Significant findings remained after controlling for individual sleep quality, duration, and wake after sleep onset. Sleep-wake concordance was associated with sleep BP, and this association was stronger for women. Higher sleep-wake concordance was associated with lower systemic inflammation for men and women. Sleep-wake concordance may be a novel mechanism by which marital relationships are associated with long-term CVD outcomes. © Sleep Research Society 2016. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.
Dynamical friction for supersonic motion in a homogeneous gaseous medium
NASA Astrophysics Data System (ADS)
Thun, Daniel; Kuiper, Rolf; Schmidt, Franziska; Kley, Wilhelm
2016-05-01
Context. The supersonic motion of gravitating objects through a gaseous ambient medium constitutes a classical problem in theoretical astrophysics. Its application covers a broad range of objects and scales from planetesimals, planets, and all kind of stars up to galaxies and black holes. In particular, the dynamical friction caused by the wake that forms behind the object plays an important role for the dynamics of the system. To calculate the dynamical friction for a particular system, standard formulae based on linear theory are often used. Aims: It is our goal to check the general validity of these formulae and provide suitable expressions for the dynamical friction acting on the moving object, based on the basic physical parameters of the problem: first, the mass, radius, and velocity of the perturber; second, the gas mass density, soundspeed, and adiabatic index of the gaseous medium; and finally, the size of the forming wake. Methods: We perform dedicated sequences of high-resolution numerical studies of rigid bodies moving supersonically through a homogeneous ambient medium and calculate the total drag acting on the object, which is the sum of gravitational and hydrodynamical drag. We study cases without gravity with purely hydrodynamical drag, as well as gravitating objects. In various numerical experiments, we determine the drag force acting on the moving body and its dependence on the basic physical parameters of the problem, as given above. From the final equilibrium state of the simulations, for gravitating objects we compute the dynamical friction by direct numerical integration of the gravitational pull acting on the embedded object. Results: The numerical experiments confirm the known scaling laws for the dependence of the dynamical friction on the basic physical parameters as derived in earlier semi-analytical studies. As a new important result we find that the shock's stand-off distance is revealed as the minimum spatial interaction scale of dynamical friction. Below this radius, the gas settles into a hydrostatic state, which - owing to its spherical symmetry - causes no net gravitational pull onto the moving body. Finally, we derive an analytic estimate for the stand-off distance that can easily be used when calculating the dynamical friction force.
The Museum of Science and Industry Basic List of Children's Science Books 1973-1984.
ERIC Educational Resources Information Center
Richter, Bernice; Wenzel, Duane
Children's science books are listed under these headings: animals; astronomy; aviation and space; biography; careers; earth sciences; encyclopedias and reference books; environment and conservation; fiction; general science; life sciences; marine life; mathematics and computer science; medical and health sciences; physics and chemistry; plant…
Active Wake Redirection Control to Improve Energy Yield (Poster)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Churchfield, M. J.; Fleming, P.; DeGeorge, E.
Wake effects can dramatically reduce the efficiency of waked turbines relative to the unwaked turbines. Wakes can be deflected, or 'redirected,' by applying yaw misalignment to the turbines. Yaw misalignment causes part of the rotor thrust vector to be pointed in the cross-stream direction, deflecting the flow and the wake. Yaw misalignment reduces power production, but the global increase in wind plant power due to decreased wake effect creates a net increase in power production. It is also a fairly simple control idea to implement at existing or new wind plants. We performed high-fidelity computational fluid dynamics simulations of themore » wake flow of the proposed Fishermen's Atlantic City Windfarm (FACW) that predict that under certain waking conditions, wake redirection can increase plant efficiency by 10%. This means that by applying wake redirection control, for a given watersheet area, a wind plant can either produce more power, or the same amount of power can be produced with a smaller watersheet area. With the power increase may come increased loads, though, due to the yaw misalignment. If misalignment is applied properly, or if layered with individual blade pitch control, though, the load increase can be mitigated. In this talk we will discuss the concept of wake redirection through yaw misalignment and present our CFD results of the FACW project. We will also discuss the implications of wake redirection control on annual energy production, and finally we will discuss plans to implement wake redirection control at FACW when it is operational.« less
Wake meandering statistics of a model wind turbine: Insights gained by large eddy simulations
NASA Astrophysics Data System (ADS)
Foti, Daniel; Yang, Xiaolei; Guala, Michele; Sotiropoulos, Fotis
2016-08-01
Wind tunnel measurements in the wake of an axial flow miniature wind turbine provide evidence of large-scale motions characteristic of wake meandering [Howard et al., Phys. Fluids 27, 075103 (2015), 10.1063/1.4923334]. A numerical investigation of the wake, using immersed boundary large eddy simulations able to account for all geometrical details of the model wind turbine, is presented here to elucidate the three-dimensional structure of the wake and the mechanisms controlling near and far wake instabilities. Similar to the findings of Kang et al. [Kang et al., J. Fluid Mech. 744, 376 (2014), 10.1017/jfm.2014.82], an energetic coherent helical hub vortex is found to form behind the turbine nacelle, which expands radially outward downstream of the turbine and ultimately interacts with the turbine tip shear layer. Starting from the wake meandering filtering used by Howard et al., a three-dimensional spatiotemporal filtering process is developed to reconstruct a three-dimensional meandering profile in the wake of the turbine. The counterwinding hub vortex undergoes a spiral vortex breakdown and the rotational component of the hub vortex persists downstream, contributing to the rotational direction of the wake meandering. Statistical characteristics of the wake meandering profile, along with triple decomposition of the flow field separating the coherent and incoherent turbulent fluctuations, are used to delineate the near and far wake flow structures and their interactions. In the near wake, the nacelle leads to mostly incoherent turbulence, while in the far wake, turbulent coherent structures, especially the azimuthal velocity component, dominate the flow field.
Rocket Science 101 Interactive Educational Program
NASA Technical Reports Server (NTRS)
Armstrong, Dennis; Funkhouse, Deborah; DiMarzio, Donald
2007-01-01
To better educate the public on the basic design of NASA s current mission rockets, Rocket Science 101 software has been developed as an interactive program designed to retain a user s attention and to teach about basic rocket parts. This program also has helped to expand NASA's presence on the Web regarding educating the public about the Agency s goals and accomplishments. The software was designed using Macromedia s Flash 8. It allows the user to select which type of rocket they want to learn about, interact with the basic parts, assemble the parts to create the whole rocket, and then review the basic flight profile of the rocket they have built.
NASA Astrophysics Data System (ADS)
Wu, Songhua; Zhai, Xiaochun; Liu, Bingyi; Liu, Jintao
2018-04-01
Field observations for the wake vortices by Coherent Doppler Lidar (CDL) have been carried out at the Beijing Capital International Airport (BCIA) and Tianjin Binhai International Airport (TBIA) to investigate the wake vortices evolution characteristics and the near-ground effect. This paper introduces the dynamic wake vortices and atmospheric turbulence monitoring technique, successfully demonstrating that the CDL can capture the key characteristics of wake vortices in real-time, including wake vortices intensity, spatial-temporal evolution and so forth.
Numerical Investigations of Active Flow Control for Low-Pressure Turbine Blades
2008-03-01
points were clustered near the wall, in the separated flow region on the suction side of the 7 blade , and in the wake . Table 1 summarizes the block...Perspective view of blade (computational domain was repeated once in spanwise direction), side view of wake , and top down view of wake . Distributions...to the wake region. A second observation is that the wake turbulence appears to be concentrated in "lumps". In analogy to other wake flows, the blade
NASA Technical Reports Server (NTRS)
Cunningham, H. J.; Vesmarais, R. N.; Yates, E. C., Jr.
1982-01-01
The influence of the trailing wake at each wing panel center is investigated. The effect of the wake is calculated by analyzing the wake as being subdivided into trailing wake strips. With the improved program there are two optional ways of calculating the wake effect, and the choice is controlled by an added parameter KANW that is part of the input data.
Application of laser velocimetry to aircraft wake-vortex measurements
NASA Technical Reports Server (NTRS)
Ciffone, D. L.; Orloff, K. L.
1977-01-01
The theory and use of a laser velocimeter that makes simultaneous measurements of vertical and longitudinal velocities while rapidly scanning a flow field laterally are described, and its direct application to trailing wake-vortex research is discussed. Pertinent measurements of aircraft wake-vortex velocity distributions obtained in a wind tunnel and water towing tank are presented. The utility of the velocimeter to quantitatively assess differences in wake velocity distributions due to wake dissipating devices and span loading changes on the wake-generating model is also demonstrated.
ASRS Reports on Wake Vortex Encounters
NASA Technical Reports Server (NTRS)
Connell, Linda J.; Taube, Elisa Ann; Drew, Charles Robert; Barclay, Tommy Earl
2010-01-01
ASRS is conducting a structured callback research project of wake vortex incidents reported to the ASRS at all US airports, as well as wake encounters in the enroute environment. This study has three objectives: (1) Utilize the established ASRS supplemental data collection methodology and provide ongoing analysis of wake vortex encounter reports; (2) Document event dynamics and contributing factors underlying wake vortex encounter events; and (3) Support ongoing FAA efforts to address pre-emptive wake vortex risk reduction by utilizing ASRS reporting contributions.
A simulation for teaching the basic and clinical science of fluid therapy.
Rawson, Richard E; Dispensa, Marilyn E; Goldstein, Richard E; Nicholson, Kimberley W; Vidal, Noni Korf
2009-09-01
The course "Management of Fluid and Electrolyte Disorders" is an applied physiology course taught using lectures and paper-based cases. The course approaches fluid therapy from both basic science and clinical perspectives. While paper cases provide a basis for application of basic science concepts, they lack key components of genuine clinical cases that, by nature, are diverse, change over time, and respond in unique ways to therapeutic interventions. We developed a dynamic model using STELLA software that simulates normal and abnormal fluid and electrolyte balance in the dog. Students interact, not with the underlying model, but with a user interface that provides sufficient data (skin turgor, chemistry panel, etc.) for the clinical assessment of patients and an opportunity for treatment. Students administer fluids and supplements, and the model responds in "real time," requiring regular reassessment and, potentially, adaptation of the treatment strategy. The level of success is determined by clinical outcome, including improvement, deterioration, or death. We expected that the simulated cases could be used to teach both the clinical and basic science of fluid therapy. The simulation provides exposure to a realistic clinical environment, and students tend to focus on this aspect of the simulation while, for the most part, ignoring an exploration of the underlying physiological basis for patient responses. We discuss how the instructor's expertise can provide sufficient support, feedback, and scaffolding so that students can extract maximum understanding of the basic science in the context of assessing and treating at the clinical level.
Wake Dynamics in the Atmospheric Boundary Layer Over Complex Terrain
NASA Astrophysics Data System (ADS)
Markfort, Corey D.
The goal of this research is to advance our understanding of atmospheric boundary layer processes over heterogeneous landscapes and complex terrain. The atmospheric boundary layer (ABL) is a relatively thin (˜ 1 km) turbulent layer of air near the earth's surface, in which most human activities and engineered systems are concentrated. Its dynamics are crucially important for biosphere-atmosphere couplings and for global atmospheric dynamics, with significant implications on our ability to predict and mitigate adverse impacts of land use and climate change. In models of the ABL, land surface heterogeneity is typically represented, in the context of Monin-Obukhov similarity theory, as changes in aerodynamic roughness length and surface heat and moisture fluxes. However, many real landscapes are more complex, often leading to massive boundary layer separation and wake turbulence, for which standard models fail. Trees, building clusters, and steep topography produce extensive wake regions currently not accounted for in models of the ABL. Wind turbines and wind farms also generate wakes that combine in complex ways to modify the ABL. Wind farms are covering an increasingly significant area of the globe and the effects of large wind farms must be included in regional and global scale models. Research presented in this thesis demonstrates that wakes caused by landscape heterogeneity must be included in flux parameterizations for momentum, heat, and mass (water vapor and trace gases, e.g. CO2 and CH4) in ABL simulation and prediction models in order to accurately represent land-atmosphere interactions. Accurate representation of these processes is crucial for the predictions of weather, air quality, lake processes, and ecosystems response to climate change. Objectives of the research reported in this thesis are: 1) to investigate turbulent boundary layer adjustment, turbulent transport and scalar flux in wind farms of varying configurations and develop an improved modeling framework for wind farm - atmosphere interaction, 2) to determine how heterogeneous patches of forest affect the structure of the ABL and its interactions with clearings and water bodies, 3) to investigate how landscape heterogeneity, including wakes, may be parameterized in regional-scale weather and climate models to improve the representation of surface fluxes, e.g. from lakes/wetlands and forest clearings. To achieve these objectives, this research employs an interdisciplinary strategy, utilizing concepts and methods from fluid mechanics, micrometeorology, ecosystem ecology and environmental sciences, and combines laboratory and field experiments. In particular, a) wind tunnel experiments of flow through and over model wind farms and model forest canopies were used to improve our fundamental understanding of how wakes affect land-atmosphere coupling, including surface fluxes, after wind farm installation and for heterogeneous landscapes of canopies and clearings or lakes, and b) extensive field studies over lakes and wetlands were undertaken to study the effects of wakes downwind of forest canopies and the effect of wind sheltering on lake stratification dynamics and gas fluxes. These experiments were also used to improve and validate numerical simulation techniques for the atmospheric boundary layer, specifically the large eddy simulation technique, which is used to simulate flow in wind farms and flow over heterogeneous terrain.
Evolution of plasma wakes in density up- and down-ramps
NASA Astrophysics Data System (ADS)
Zhang, C. J.; Joshi, C.; Xu, X. L.; Mori, W. B.; Li, F.; Wan, Y.; Hua, J. F.; Pai, C. H.; Wang, J.; Lu, W.
2018-02-01
The time evolution of plasma wakes in density up- and down-ramps is examined through theory and particle-in-cell simulations. Motivated by observation of the reversal of a linear plasma wake in a plasma density upramp in a recent experiment (Zhang et al 2017 Phys. Rev. Lett. 119 064801) we have examined the behaviour of wakes in plasma ramps that always accompany any plasma source used for plasma-based acceleration. In the up-ramp case it is found that, after the passage of the drive pulse, the wavnumber/wavelength of the wake starts to decrease/increase with time until it eventually tends to zero/infinity, then the wake reverses its propagation direction and the wavenunber/wavelength of the wake begins to increase/shrink. The evolutions of the wavenumber and the phase velocity of the wake as functions of time are shown to be significantly different in the up-ramp and the down-ramp cases. In the latter case the wavenumber of the wake at a particular position in the ramp increases until the wake is eventually damped. It is also shown that the waveform of the wake at a particular time after being excited can be precisely controlled by tuning the initial plasma density profile, which may enable a new type of plasma-based ultrafast optics.
EEG power during waking and NREM sleep in primary insomnia.
Wu, You Meme; Pietrone, Regina; Cashmere, J David; Begley, Amy; Miewald, Jean M; Germain, Anne; Buysse, Daniel J
2013-10-15
Pathophysiological models of insomnia invoke the concept of 24-hour hyperarousal, which could lead to symptoms and physiological findings during waking and sleep. We hypothesized that this arousal could be seen in the waking electroencephalogram (EEG) of individuals with primary insomnia (PI), and that waking EEG power would correlate with non-REM (NREM) EEG. Subjects included 50 PI and 32 good sleeper controls (GSC). Five minutes of eyes closed waking EEG were collected at subjects' usual bedtimes, followed by polysomnography (PSG) at habitual sleep times. An automated algorithm and visual editing were used to remove artifacts from waking and sleep EEGs, followed by power spectral analysis to estimate power from 0.5-32 Hz. We did not find significant differences in waking or NREM EEG spectral power of PI and GSC. Significant correlations between waking and NREM sleep power were observed across all frequency bands in the PI group and in most frequency bands in the GSC group. The absence of significant differences between groups in waking or NREM EEG power suggests that our sample was not characterized by a high degree of cortical arousal. The consistent correlations between waking and NREM EEG power suggest that, in samples with elevated NREM EEG beta activity, waking EEG power may show a similar pattern.
Boes, Aaron D; Fischer, David; Geerling, Joel C; Bruss, Joel; Saper, Clifford B; Fox, Michael D
2018-05-29
The hypothalamus is a central hub for regulating sleep-wake patterns, the circuitry of which has been investigated extensively in experimental animals. This work has identified a wake-promoting region in the posterior hypothalamus, with connections to other wake-promoting regions, and a sleep-promoting region in the anterior hypothalamus, with inhibitory projections to the posterior hypothalamus. It is unclear whether a similar organization exists in humans. Here, we use anatomical landmarks to identify homologous sleep and wake-promoting regions of the human hypothalamus and investigate their functional relationships using resting-state functional connectivity MRI in healthy awake participants. First, we identify a negative correlation (anticorrelation) between the anterior and posterior hypothalamus, two regions with opposing roles in sleep-wake regulation. Next, we show that hypothalamic connectivity predicts a pattern of regional sleep-wake changes previously observed in humans. Specifically, regions that are more positively correlated with the posterior hypothalamus and more negatively correlated with the anterior hypothalamus correspond to regions with the greatest change in cerebral blood flow between sleep-wake states. Taken together, these findings provide preliminary evidence relating a hypothalamic circuit investigated in animals to sleep-wake neuroimaging results in humans, with implications for our understanding of human sleep-wake regulation and the functional significance of anticorrelations.
Utilization and acceptance of virtual patients in veterinary basic sciences - the vetVIP-project.
Kleinsorgen, Christin; Kankofer, Marta; Gradzki, Zbigniew; Mandoki, Mira; Bartha, Tibor; von Köckritz-Blickwede, Maren; Naim, Hassan Y; Beyerbach, Martin; Tipold, Andrea; Ehlers, Jan P
2017-01-01
Context: In medical and veterinary medical education the use of problem-based and cased-based learning has steadily increased over time. At veterinary faculties, this development has mainly been evident in the clinical phase of the veterinary education. Therefore, a consortium of teachers of biochemistry and physiology together with technical and didactical experts launched the EU-funded project "vetVIP", to create and implement veterinary virtual patients and problems for basic science instruction. In this study the implementation and utilization of virtual patients occurred at the veterinary faculties in Budapest, Hannover and Lublin. Methods: This report describes the investigation of the utilization and acceptance of students studying veterinary basic sciences using optional online learning material concurrently to regular biochemistry and physiology didactic instruction. The reaction of students towards this offer of clinical case-based learning in basic sciences was analysed using quantitative and qualitative data. Quantitative data were collected automatically within the chosen software-system CASUS as user-log-files. Responses regarding the quality of the virtual patients were obtained using an online questionnaire. Furthermore, subjective evaluation by authors was performed using a focus group discussion and an online questionnaire. Results: Implementation as well as usage and acceptance varied between the three participating locations. High approval was documented in Hannover and Lublin based upon the high proportion of voluntary students (>70%) using optional virtual patients. However, in Budapest the participation rate was below 1%. Due to utilization, students seem to prefer virtual patients and problems created in their native language and developed at their own university. In addition, the statement that assessment drives learning was supported by the observation that peak utilization was just prior to summative examinations. Conclusion: Veterinary virtual patients in basic sciences can be introduced and used for the presentation of integrative clinical case scenarios. Student post-course comments also supported the conclusion that overall the virtual cases increased their motivation for learning veterinary basic sciences.
Circadian Sleep-Wake Rhythm of Older Adults with Intellectual Disabilities
ERIC Educational Resources Information Center
Maaskant, Marijke; van de Wouw, Ellen; van Wijck, Ruud; Evenhuis, Heleen M.; Echteld, Michael A.
2013-01-01
The circadian sleep-wake rhythm changes with aging, resulting in a more fragmented sleep-wake pattern. In individuals with intellectual disabilities (ID), brain structures regulating the sleep-wake rhythm might be affected. The aims of this study were to compare the sleep-wake rhythm of older adults with ID to that of older adults in the general…
Opportunities for Computational Discovery in Basic Energy Sciences
NASA Astrophysics Data System (ADS)
Pederson, Mark
2011-03-01
An overview of the broad-ranging support of computational physics and computational science within the Department of Energy Office of Science will be provided. Computation as the third branch of physics is supported by all six offices (Advanced Scientific Computing, Basic Energy, Biological and Environmental, Fusion Energy, High-Energy Physics, and Nuclear Physics). Support focuses on hardware, software and applications. Most opportunities within the fields of~condensed-matter physics, chemical-physics and materials sciences are supported by the Officeof Basic Energy Science (BES) or through partnerships between BES and the Office for Advanced Scientific Computing. Activities include radiation sciences, catalysis, combustion, materials in extreme environments, energy-storage materials, light-harvesting and photovoltaics, solid-state lighting and superconductivity.~ A summary of two recent reports by the computational materials and chemical communities on the role of computation during the next decade will be provided. ~In addition to materials and chemistry challenges specific to energy sciences, issues identified~include a focus on the role of the domain scientist in integrating, expanding and sustaining applications-oriented capabilities on evolving high-performance computing platforms and on the role of computation in accelerating the development of innovative technologies. ~~
Storytelling in Earth sciences: The eight basic plots
NASA Astrophysics Data System (ADS)
Phillips, Jonathan
2012-11-01
Reporting results and promoting ideas in science in general, and Earth science in particular, is treated here as storytelling. Just as in literature and drama, storytelling in Earth science is characterized by a small number of basic plots. Though the list is not exhaustive, and acknowledging that multiple or hybrid plots and subplots are possible in a single piece, eight standard plots are identified, and examples provided: cause-and-effect, genesis, emergence, destruction, metamorphosis, convergence, divergence, and oscillation. The plots of Earth science stories are not those of literary traditions, nor those of persuasion or moral philosophy, and deserve separate consideration. Earth science plots do not conform those of storytelling more generally, implying that Earth scientists may have fundamentally different motivations than other storytellers, and that the basic plots of Earth Science derive from the characteristics and behaviors of Earth systems. In some cases preference or affinity to different plots results in fundamentally different interpretations and conclusions of the same evidence. In other situations exploration of additional plots could help resolve scientific controversies. Thus explicit acknowledgement of plots can yield direct scientific benefits. Consideration of plots and storytelling devices may also assist in the interpretation of published work, and can help scientists improve their own storytelling.
Open Science: a first step towards Science Communication
NASA Astrophysics Data System (ADS)
Grigorov, Ivo; Tuddenham, Peter
2015-04-01
As Earth Science communicators gear up to adopt the new tools and captivating approaches to engage citizen scientists, budding entrepreneurs, policy makers and the public in general, researchers have the responsibility, and opportunity, to fully adopt Open Science principles and capitalize on its full societal impact and engagement. Open Science is about removing all barriers to basic research, whatever its formats, so that it can be freely used, re-used and re-hashed, thus fueling discourse and accelerating generation of innovative ideas. The concept is central to EU's Responsible Research and Innovation philosophy, and removing barriers to basic research measurably contributes to engaging citizen scientists into the research process, it sets the scene for co-creation of solutions to societal challenges, and raises the general science literacy level of the public. Despite this potential, only 50% of today's basic research is freely available. Open Science can be the first passive step of communicating marine research outside academia. Full and unrestricted access to our knowledge including data, software code and scientific publications is not just an ethical obligation, but also gives solid credibility to a more sophisticated communication strategy on engaging society. The presentation will demonstrate how Open Science perfectly compliments a coherent communication strategy for placing Marine Research in societal context, and how it underpin an effective integration of Ocean & Earth Literacy principles in standard educational, as well mobilizing citizen marine scientists, thus making marine science Open Science.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Churchfield, M.; Wang, Q.; Scholbrock, A.
Here, we describe the process of using large-eddy simulations of wind turbine wake flow to help design a wake measurement campaign. The main goal of the experiment is to measure wakes and wake deflection that result from intentional yaw misalignment under a variety of atmospheric conditions at the Scaled Wind Farm Technology facility operated by Sandia National Laboratories in Lubbock, Texas. Prior simulation studies have shown that wake deflection may be used for wind-plant control that maximizes plant power output. In this study, simulations are performed to characterize wake deflection and general behavior before the experiment is performed to ensuremore » better upfront planning. Beyond characterizing the expected wake behavior, we also use the large-eddy simulation to test a virtual version of the lidar we plan to use to measure the wake and better understand our lidar scan strategy options. This work is an excellent example of a 'simulation-in-the-loop' measurement campaign.« less
NASA Astrophysics Data System (ADS)
Churchfield, M.; Wang, Q.; Scholbrock, A.; Herges, T.; Mikkelsen, T.; Sjöholm, M.
2016-09-01
We describe the process of using large-eddy simulations of wind turbine wake flow to help design a wake measurement campaign. The main goal of the experiment is to measure wakes and wake deflection that result from intentional yaw misalignment under a variety of atmospheric conditions at the Scaled Wind Farm Technology facility operated by Sandia National Laboratories in Lubbock, Texas. Prior simulation studies have shown that wake deflection may be used for wind-plant control that maximizes plant power output. In this study, simulations are performed to characterize wake deflection and general behavior before the experiment is performed to ensure better upfront planning. Beyond characterizing the expected wake behavior, we also use the large-eddy simulation to test a virtual version of the lidar we plan to use to measure the wake and better understand our lidar scan strategy options. This work is an excellent example of a “simulation-in-the-loop” measurement campaign.
Structure Function Scaling Exponent and Intermittency in the Wake of a Wind Turbine Array
NASA Astrophysics Data System (ADS)
Aseyev, Aleksandr; Ali, Naseem; Cal, Raul
2015-11-01
Hot-wire measurements obtained in a 3 × 3 wind turbine array boundary layer are utilized to analyze high order structure functions, intermittency effects as well as the probability density functions of velocity increments at different scales within the energy cascade. The intermittency exponent is found to be greater in the far wake region in comparison to the near wake. At hub height, the intermittency exponent is found to be null. ESS scaling exponents of the second, fourth, and fifth order structure functions remain relatively constant as a function of height in the far-wake whereas in the near-wake these highly affected by the passage of the rotor thus showing a dependence on physical location. When comparing with proposed models, these generally over predict the structure functions in the far wake region. The pdf distributions in the far wake region display wider tails compared to the near wake region, and constant skewness hypothesis based on the local isotropy is verified in the wake. CBET-1034581.
Churchfield, M.; Wang, Q.; Scholbrock, A.; ...
2016-10-03
Here, we describe the process of using large-eddy simulations of wind turbine wake flow to help design a wake measurement campaign. The main goal of the experiment is to measure wakes and wake deflection that result from intentional yaw misalignment under a variety of atmospheric conditions at the Scaled Wind Farm Technology facility operated by Sandia National Laboratories in Lubbock, Texas. Prior simulation studies have shown that wake deflection may be used for wind-plant control that maximizes plant power output. In this study, simulations are performed to characterize wake deflection and general behavior before the experiment is performed to ensuremore » better upfront planning. Beyond characterizing the expected wake behavior, we also use the large-eddy simulation to test a virtual version of the lidar we plan to use to measure the wake and better understand our lidar scan strategy options. This work is an excellent example of a 'simulation-in-the-loop' measurement campaign.« less
On the investigation of cascade and turbomachinery rotor wake characteristics
NASA Technical Reports Server (NTRS)
Raj, R.; Lakshminarayana, B.
1975-01-01
The objective of the investigation reported in this thesis is to study the characteristics of a turbomachinery rotor wake, both analytically and experimentally. The constitutive equations for the rotor wake are developed using generalized tensors and a non-inertial frame of reference. Analytical and experimental investigation is carried out in two phases; the first phase involved the study of a cascade wake in the absence of rotation and three dimensionality. In the second phase the wake of a rotor is studied. Simplified two- and three-dimensional models are developed for the prediction of the mean velocity profile of the cascade and the rotor wake, respectively, using the principle of self-similarity. The effect of various major parameters of the rotor and the flow geometry is studied on the development of a rotor wake. Laws governing the decay of the wake velocity defect in a cascade and rotor wake as a function of downstream distance from the trailing edge, pressure gradient and other parameters are derived.
Analysis of an entrainment model of the jet in a crossflow
NASA Technical Reports Server (NTRS)
Chang, H. S.; Werner, J. E.
1972-01-01
A theoretical model has been proposed for the problem of a round jet in an incompressible cross-flow. The method of matched asymptotic expansions has been applied to this problem. For the solution to the flow problem in the inner region, the re-entrant wake flow model was used with the re-entrant flow representing the fluid entrained by the jet. Higher order corrections are obtained in terms of this basic solution. The perturbation terms in the outer region was found to be a line distribution of doublets and sources. The line distribution of sources represents the combined effect of the entrainment and the displacement.
Heart rate changes in partial seizures: analysis of influencing factors among refractory patients
2014-01-01
Background We analyzed the frequency of heart rate (HR) changes related to seizures, and we sought to identify the influencing factors of these changes during partial seizures, to summarize the regularity of the HR changes and gain some insight into the mechanisms involved in the neuronal regulation of cardiovascular function. To date, detailed information on influencing factors of HR changes related to seizures by multiple linear regression analysis remains scarce. Methods Using video-electroencephalograph (EEG)-electrocardiograph (ECG) recordings, we retrospectively assessed the changes in the HR of 81 patients during a total of 181 seizures, including 27 simple partial seizures (SPS), 110 complex partial seizures (CPS) and 44 complex partial seizures secondarily generalized (CPS-G). The epileptogenic focus and the seizure type, age, gender, and sleep/wakefulness state of each patient were evaluated during and after the seizure onset. The HR changes were evaluated in the stage of epilepsy as time varies. Results Of the 181 seizures from 81 patients with ictal ECGs, 152 seizures (83.98%) from 74 patients were accompanied by ictal tachycardia (IT). And only 1 patient was accompanied by ictal bradycardia (IB). A patient has both IT and IB. We observed that HR difference was independently correlated with side, type and sleep/wakefulness state. In this analysis, the HR changes were related to the side, gender, seizure type, and sleep/wakefulness state. Right focus, male, sleep, and CPS-G showed more significant increases than that were observed in left, female, wakefulness, SPS and CPS. HR increases rapidly within 10 seconds before seizure onset and ictus, and typically slows to normal with seizure offset. Conclusion CPS-G, sleep and right focus led to higher ictal HR. The HR in the stage of epilepsy has regularly been observed to change to become time-varying. The risk factors of ictal HR need to be controlled along with sleep, CPS-G and right focus. Our study first explains that the HR in seizures has a regular evolution varying with time. Our study might help to further clarify the basic mechanisms of interactions between heart and brain, making seizure detection and closed-loop systems a possible therapeutic alternative in refractory patients. PMID:24950859
ARCHITECTURAL DRAWING, MILITARY AIR COMMAND COMMUNICATION CENTER PRECAST CONCRETE WALL ...
ARCHITECTURAL DRAWING, MILITARY AIR COMMAND COMMUNICATION CENTER PRECAST CONCRETE WALL DETAILS. DATED 03/15/1971 - Wake Island Airfield, Terminal Building, West Side of Wake Avenue, Wake Island, Wake Island, UM
DOE Office of Scientific and Technical Information (OSTI.GOV)
Doubrawa, P.; Barthelmie, R. J.; Wang, H.
The contribution of wake meandering and shape asymmetry to load and power estimates is quantified by comparing aeroelastic simulations initialized with different inflow conditions: an axisymmetric base wake, an unsteady stochastic shape wake, and a large-eddy simulation with rotating actuator-line turbine representation. Time series of blade-root and tower base bending moments are analyzed. We find that meandering has a large contribution to the fluctuation of the loads. Moreover, considering the wake edge intermittence via the stochastic shape model improves the simulation of load and power fluctuations and of the fatigue damage equivalent loads. Furthermore, these results indicate that the stochasticmore » shape wake simulator is a valuable addition to simplified wake models when seeking to obtain higher-fidelity computationally inexpensive predictions of loads and power.« less
Proceedings of the NASA First Wake Vortex Dynamic Spacing Workshop
NASA Technical Reports Server (NTRS)
Creduer, Leonard (Editor); Perry, R. Brad (Editor)
1997-01-01
A Government and Industry workshop on wake vortex dynamic spacing systems was conducted on May 13-15, 1997, at the NASA Langley Research Center. The purpose of the workshop was to disclose the status of ongoing NASA wake vortex R&D to the international community and to seek feedback on the direction of future work to assure an optimized research approach. Workshop sessions examined wake vortex characterization and physics, wake sensor technologies, aircraft/wake encounters, terminal area weather characterization and prediction, and wake vortex systems integration and implementation. A final workshop session surveyed the Government and Industry perspectives on the NASA research underway and related international wake vortex activities. This document contains the proceedings of the workshop including the presenters' slides, the discussion following each presentation, the wrap-up panel discussion, and the attendees' evaluation feedback.
Doubrawa, P.; Barthelmie, R. J.; Wang, H.; ...
2016-10-03
The contribution of wake meandering and shape asymmetry to load and power estimates is quantified by comparing aeroelastic simulations initialized with different inflow conditions: an axisymmetric base wake, an unsteady stochastic shape wake, and a large-eddy simulation with rotating actuator-line turbine representation. Time series of blade-root and tower base bending moments are analyzed. We find that meandering has a large contribution to the fluctuation of the loads. Moreover, considering the wake edge intermittence via the stochastic shape model improves the simulation of load and power fluctuations and of the fatigue damage equivalent loads. Furthermore, these results indicate that the stochasticmore » shape wake simulator is a valuable addition to simplified wake models when seeking to obtain higher-fidelity computationally inexpensive predictions of loads and power.« less
Wake shed by an accelerating carangiform fish
NASA Astrophysics Data System (ADS)
Ting, Shang-Chieh; Yang, Jing-Tang
2008-11-01
We reveal an important fact that momentum change observed in the wake of an accelerating carangiform fish does not necessarily elucidate orientations of propulsive forces produced. An accelerating Crucian Carp (Carassius auratus) was found to shed a wake with net forward fluid momentum, which seemed drag-producing. Based on Newton's law, however, an accelerating fish is expected to shed a thrust wake with net rearward fluid momentum, rather than a drag wake. The unusual wake pattern observed is considered to be resulted primarily from the effect of pressure gradient created by accelerating movements of the fish. Ambient fluids tend to be sucked into low pressure zones behind an accelerating fish, resulting in forward orientations of jets recognizable in the wake. Accordingly, as to an accelerating fish, identifying force orientations from the wake requires considering also the effect of pressure gradient.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gebraad, Pieter; Thomas, Jared J.; Ning, Andrew
This paper presents a wind plant modeling and optimization tool that enables the maximization of wind plant annual energy production (AEP) using yaw-based wake steering control and layout changes. The tool is an extension of a wake engineering model describing the steady-state effects of yaw on wake velocity profiles and power productions of wind turbines in a wind plant. To make predictions of a wind plant's AEP, necessary extensions of the original wake model include coupling it with a detailed rotor model and a control policy for turbine blade pitch and rotor speed. This enables the prediction of power productionmore » with wake effects throughout a range of wind speeds. We use the tool to perform an example optimization study on a wind plant based on the Princess Amalia Wind Park. In this case study, combined optimization of layout and wake steering control increases AEP by 5%. The power gains from wake steering control are highest for region 1.5 inflow wind speeds, and they continue to be present to some extent for the above-rated inflow wind speeds. The results show that layout optimization and wake steering are complementary because significant AEP improvements can be achieved with wake steering in a wind plant layout that is already optimized to reduce wake losses.« less
NASA Technical Reports Server (NTRS)
Brockman, Philip; Barker, Ben C., Jr.; Koch, Grady J.; Nguyen, Dung Phu Chi; Britt, Charles L., Jr.; Petros, Mulugeta
1999-01-01
NASA Langley Research Center (LaRC) has field tested a 2.0 gm, 100 Hertz, pulsed coherent lidar to detect and characterize wake vortices and to measure atmospheric winds and turbulence. The quantification of aircraft wake-vortex hazards is being addressed by the Wake Vortex Lidar (WVL) Project as part of Aircraft Vortex Spacing System (AVOSS), which is under the Reduced Spacing Operations Element of the Terminal Area Productivity (TAP) Program. These hazards currently set the minimum, fixed separation distance between two aircraft and affect the number of takeoff and landing operations on a single runway under Instrument Meteorological Conditions (IMC). The AVOSS concept seeks to safely reduce aircraft separation distances, when weather conditions permit, to increase the operational capacity of major airports. The current NASA wake-vortex research efforts focus on developing and validating wake vortex encounter models, wake decay and advection models, and wake sensing technologies. These technologies will be incorporated into an automated AVOSS that can properly select safe separation distances for different weather conditions, based on the aircraft pair and predicted/measured vortex behavior. The sensor subsystem efforts focus on developing and validating wake sensing technologies. The lidar system has been field-tested to provide real-time wake vortex trajectory and strength data to AVOSS for wake prediction verification. Wake vortices, atmospheric winds, and turbulence products have been generated from processing the lidar data collected during deployments to Norfolk (ORF), John F. Kennedy (JFK), and Dallas/Fort Worth (DFW) International Airports.
2016-09-01
AWARD NUMBER: W811XWH-13-1-0310 TITLE: Acceleration of Regeneration of Large-Gap Peripheral Nerve Injuries Using Acellular Nerve Allografts...plus amniotic Fluid Derived Stem Cells (AFS). PRINCIPAL INVESTIGATOR: Zhongyu Li, MD, PhD RECIPIENT: Wake Forest University Health Sciences...REPORT DATE September 2016 2. REPORT TYPE Annual 3. DATES COVERED 1Sep2015 - 31Aug2016 4. TITLE AND SUBTITLE Acceleration of Regeneration of Large
Large and small-scale structures in Saturn's rings
NASA Astrophysics Data System (ADS)
Albers, N.; Rehnberg, M. E.; Brown, Z. L.; Sremcevic, M.; Esposito, L. W.
2017-09-01
Observations made by the Cassini spacecraft have revealed both large and small scale structures in Saturn's rings in unprecedented detail. Analysis of high-resolution measurements by the Cassini Ultraviolet Spectrograph (UVIS) High Speed Photometer (HSP) and the Imaging Science Subsystem (ISS) show an abundance of intrinsic small-scale structures (or clumping) seen across the entire ring system. These include self-gravity wakes (50-100m), sub-km structure at the A and B ring edges, and "straw"/"ropy" structures (1-3km).
Conservation of Sooty Terns on Wake Atoll Complex
2011-05-01
Ascension Island. Atlantic Seabirds 1:159-168. Robertson, W. B. 1964. The terns of the Dry Tortugas . Bulletin of the Florida State Museum 8:1-94 Saliva...Science 60(2):299–303. Sprunt, A. Jr. 1948. The tern colonies of the Dry Tortugas Keys. Auk 65: 1-19. Surman, C. A. and L. W. Nicholson. 2009...5:518-531. Watson, J. B. 1908. The behavior of Noddy and Sooty Terns. Papers from the Tortugas Lab 2:187-255. Wilcove, D. S., D. Rothstein, J
Wake meandering of a model wind turbine operating in two different regimes
NASA Astrophysics Data System (ADS)
Foti, Daniel; Yang, Xiaolei; Campagnolo, Filippo; Maniaci, David; Sotiropoulos, Fotis
2018-05-01
The flow behind a model wind turbine under two different turbine operating regimes (region 2 for turbine operating at optimal condition with the maximum power coefficient and 1.4-deg pitch angle and region 3 for turbine operating at suboptimal condition with a lower power coefficient and 7-deg pitch angle) is investigated using wind tunnel experiments and numerical experiments using large-eddy simulation (LES) with actuator surface models for turbine blades and nacelle. Measurements from the model wind turbine experiment reveal that the power coefficient and turbine wake are affected by the operating regime. Simulations with and without a nacelle model are carried out for each operating condition to study the influence of the operating regime and nacelle on the formation of the hub vortex and wake meandering. Statistics and energy spectra of the simulated wakes are in good agreement with the measurements. For simulations with a nacelle model, the mean flow field is composed of an outer wake, caused by energy extraction by turbine blades, and an inner wake directly behind the nacelle, while for the simulations without a nacelle model, the central region of the wake is occupied by a jet. The simulations with the nacelle model reveal an unstable helical hub vortex expanding outward toward the outer wake, while the simulations without a nacelle model show a stable and columnar hub vortex. Because of the different interactions of the inner region of the wake with the outer region of the wake, a region with higher turbulence intensity is observed in the tip shear layer for the simulation with a nacelle model. The hub vortex for the turbine operating in region 3 remains in a tight helical spiral and intercepts the outer wake a few diameters further downstream than for the turbine operating in region 2. Wake meandering, a low-frequency large-scale motion of the wake, commences in the region of high turbulence intensity for all simulations with and without a nacelle model, indicating that neither a nacelle model nor an unstable hub vortex is a necessary requirement for the existence of wake meandering. However, further analysis of the wake meandering and instantaneous flow field using a filtering technique and dynamic mode decomposition show that the unstable hub vortex energizes the wake meandering. The turbine operating regime affects the shape and expansion of the hub vortex, altering the location of the onset of the wake meandering and wake meander oscillating intensity. Most important, the unstable hub vortex promotes a high-amplitude energetic meandering which cannot be predicted without a nacelle model.
Life-science research within US academic medical centers.
Zinner, Darren E; Campbell, Eric G
2009-09-02
Besides the generic "basic" vs "applied" labels, little information is known about the types of life-science research conducted within academic medical centers (AMCs). To determine the relative proportion, characteristics, funding, and productivity of AMC faculty by the type of research they conduct. Mailed survey conducted in 2007 of 3080 life-science faculty at the 50 universities with medical schools that received the most funding from the National Institutes of Health in 2004. Response rate was 74%. Research faculty affiliated with a medical school or teaching hospital, representing 77% of respondents (n = 1663). Type of research (basic, translational, clinical trials, health services research/clinical epidemiology, multimode, other), total funding, industry funding, publications, professional activities, patenting behavior, and industry relationships. Among AMC research faculty, 33.6% exclusively conducted basic science research as principal investigators compared with translational researchers (9.1%), clinical trial investigators (7.1%), and health services researchers/clinical epidemiologists (9.0%). While principal investigators garnered a mean of $410,755 in total annual research funding, 22.1% of all AMC research faculty were unsponsored, a proportion that ranged from 11.5% for basic science researchers to 46.8% for health services researchers (P < .001). The average AMC faculty member received $33,417 in industry-sponsored funding, with most of this money concentrated among clinical trial ($110,869) and multimode ($59,916) principal investigators. Translational (61.3%), clinical trial (67.3%), and multimode (70.9%) researchers were significantly more likely than basic science researchers (41.9%) to report a relationship with industry and that these relationships contributed to their most important scientific work (P < .05 for all comparisons). The research function of AMCs is active and diverse, incorporating a substantial proportion of faculty who are conducting research and publishing without sponsorship.
Wake flowfields for Jovian probe
NASA Technical Reports Server (NTRS)
Engel, C. D.; Hair, L. M.
1980-01-01
The wake flow field developed by the Galileo probe as it enters the Jovian atmosphere was modeled. The wake produced by the probe is highly energetic, yielding both convective and radiative heat inputs to the base of the probe. A component mathematical model for the inviscid near and far wake, the viscous near and far wake, and near wake recirculation zone was developed. Equilibrium thermodynamics were used for both the ablation and atmospheric species. Flow fields for three entry conditions were calculated. The near viscous wave was found to exhibit a variable axial pressure distribution with the neck pressure approximately three times the base pressure. Peak wake flow field temperatures were found to be in proportion to forebody post shock temperatures.
Aligning library instruction with the needs of basic sciences graduate students: a case study.
O'Malley, Donna; Delwiche, Frances A
2012-10-01
How can an existing library instruction program be reconfigured to reach basic sciences graduate students and other patrons missed by curriculum-based instruction? The setting is an academic health sciences library that serves both the university and its affiliated teaching hospital. The existing program was redesigned to incorporate a series of seven workshops that encompassed the range of information literacy skills that graduate students in the basic sciences need. In developing the new model, the teaching librarians made changes in pedagogy, technology, marketing, and assessment strategies. Total attendance at the sessions increased substantially in the first 2 years of the new model, increasing from an average of 20 per semester to an average of 124. Survey results provided insight about what patrons wanted to learn and how best to teach it. Modifying the program's content and structure resulted in a program that appealed to the target audience.
Comparison of Basic Science Knowledge Between DO and MD Students.
Davis, Glenn E; Gayer, Gregory G
2017-02-01
With the coming single accreditation system for graduate medical education, medical educators may wonder whether knowledge in basic sciences is equivalent for osteopathic and allopathic medical students. To examine whether medical students' basic science knowledge is the same among osteopathic and allopathic medical students. A dataset of the Touro University College of Osteopathic Medicine-CA student records from the classes of 2013, 2014, and 2015 and the national cohort of National Board of Medical Examiners Comprehensive Basic Science Examination (NBME-CBSE) parameters for MD students were used. Models of the Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) Level 1 scores were fit using linear and logistic regression. The models included variables used in both osteopathic and allopathic medical professions to predict COMLEX-USA outcomes, such as Medical College Admission Test biology scores, preclinical grade point average, number of undergraduate science units, and scores on the NBME-CBSE. Regression statistics were studied to compare the effectiveness of models that included or excluded NBME-CBSE scores at predicting COMLEX-USA Level 1 scores. Variance inflation factor was used to investigate multicollinearity. Receiver operating characteristic curves were used to show the effectiveness of NBME-CBSE scores at predicting COMLEX-USA Level 1 pass/fail outcomes. A t test at 99% level was used to compare mean NBME-CBSE scores with the national cohort. A total of 390 student records were analyzed. Scores on the NBME-CBSE were found to be an effective predictor of COMLEX-USA Level 1 scores (P<.001). The pass/fail outcome on COMLEX-USA Level 1 was also well predicted by NBME-CBSE scores (P<.001). No significant difference was found in performance on the NBME-CBSE between osteopathic and allopathic medical students (P=.322). As an examination constructed to assess the basic science knowledge of allopathic medical students, the NBME-CBSE is effective at predicting performance on COMLEX-USA Level 1. In addition, osteopathic medical students performed the same as allopathic medical students on the NBME-CBSE. The results imply that the same basic science knowledge is expected for DO and MD students.
Self-preservation of turbulent wakes
NASA Technical Reports Server (NTRS)
Mehta, Jayesh M.
1989-01-01
The present experiment has ascertained the development of the wake flow behind NASA GA(W)-1 airfoils, showing that, in the far wake, the mean velocity profiles exhibit self-similar behavior irrespective of the upstream boundary layer's character. It is noted, however, that the processes by means of which different wakes reach the asymptotic stage can be very different for different types of wake generators.
NASA Astrophysics Data System (ADS)
Jackson, Deborah C.; Johnson, Elizabeth D.
2013-09-01
The problem of students entering university lacking basic mathematical skills is a critical issue in the Australian higher-education sector and relevant globally. The Maths Skills programme at La Trobe University has been developed to address under preparation in the first-year science cohort in the absence of an institutional mathematics support centre. The programme was delivered through first-year science and statistics subjects with large enrolments and focused on basic mathematical skills relevant to each science discipline. The programme offered a new approach to the traditional mathematical support centre or class. It was designed through close collaboration between science subject coordinators and the project leader, a mathematician, and includes resources relevant to science and mathematics questions written in context. Evaluation of the programme showed it improved the confidence of the participating students who found it helpful and relevant. The programme was delivered through three learning modes to allow students to select activities most suitable for them, which was appreciated by students. Mathematics skills appeared to increase following completion of the programme and student participation in the programme correlated positively and highly with academic grades in their relevant science subjects. This programme offers an alternative model for mathematics support tailored to science disciplines.
Progressive Loss of the Orexin Neurons Reveals Dual Effects on Wakefulness
Branch, Abigail F.; Navidi, William; Tabuchi, Sawako; Terao, Akira; Yamanaka, Akihiro; Scammell, Thomas E.; Diniz Behn, Cecilia
2016-01-01
Study Objectives: Narcolepsy is caused by loss of the orexin (also known as hypocretin) neurons. In addition to the orexin peptides, these neurons release additional neurotransmitters, which may produce complex effects on sleep/wake behavior. Currently, it remains unknown whether the orexin neurons promote the initiation as well as the maintenance of wakefulness, and whether the orexin neurons influence initiation or maintenance of sleep. To determine the effects of the orexin neurons on the dynamics of sleep/wake behavior, we analyzed sleep/wake architecture in a novel mouse model of acute orexin neuron loss. Methods: We used survival analysis and other statistical methods to analyze sleep/wake architecture in orexin-tTA ; TetO diphtheria toxin A mice at different stages of orexin neuron degeneration. Results: Progressive loss of the orexin neurons dramatically reduced survival of long wake bouts, but it also improved survival of brief wake bouts. In addition, with loss of the orexin neurons, mice were more likely to wake during the first 30 sec of nonrapid eye movement sleep and then less likely to return to sleep during the first 60 sec of wakefulness. Conclusions: These findings help explain the sleepiness and fragmented sleep that are characteristic of narcolepsy. Orexin neuron loss impairs survival of long wake bouts resulting in poor maintenance of wakefulness, but this neuronal loss also fragments sleep by increasing the risk of awakening at the beginning of sleep and then reducing the likelihood of quickly returning to sleep. Citation: Branch AF, Navidi W, Tabuchi S, Terao A, Yamanaka A, Scammell TE, Diniz Behn C. Progressive loss of the orexin neurons reveals dual effects on wakefulness. SLEEP 2016;39(2):369–377. PMID:26446125
NASA Astrophysics Data System (ADS)
Satta, Francesca; Ubaldi, Marina; Zunino, Pietro
2012-04-01
An experimental investigation on the near and far wake of a cascade of high-lift low-pressure turbine blades subjected to boundary layer separation over the suction side surface has been carried out, under steady and unsteady inflows. Two Reynolds number conditions, representative of take-off/landing and cruise operating conditions of the real engine, have been tested. The effect of upstream wake-boundary layer interaction on the wake shed from the profile has been investigated in a three-blade large-scale linear turbine cascade. The comparison between the wakes shed under steady and unsteady inflows has been performed through the analysis of mean velocity and Reynolds stress components measured at midspan of the central blade by means of a two-component crossed miniature hot-wire probe. The wake development has been analyzed in the region between 2% and 100% of the blade chord from the central blade trailing edge, aligned with the blade exit direction. Wake integral parameters, half-width and maximum velocity defects have been evaluated from the mean velocity distributions to quantify the modifications induced on the vane wake by the upstream wake. Moreover the thicknesses of the two wake shear layers have been considered separately in order to identify the effects of Reynolds number and incoming flow on the wake shape. The self-preserving state of the wake has been looked at, taking into account the different thicknesses of the two shear layers. The evaluation of the power density spectra of the velocity fluctuations allowed the study of the wake unsteady behavior, and the detection of the effects induced by the different operating conditions on the trailing edge vortex shedding.
A Study of Wake Development and Structure in Constant Pressure Gradients
NASA Technical Reports Server (NTRS)
Thomas, Flint O.; Nelson, R. C.; Liu, Xiaofeng
2000-01-01
Motivated by the application to high-lift aerodynamics for commercial transport aircraft, a systematic investigation into the response of symmetric/asymmetric planar turbulent wake development to constant adverse, zero, and favorable pressure gradients has been conducted. The experiments are performed at a Reynolds number of 2.4 million based on the chord of the wake generator. A unique feature of this wake study is that the pressure gradients imposed on the wake flow field are held constant. The experimental measurements involve both conventional LDV and hot wire flow field surveys of mean and turbulent quantities including the turbulent kinetic energy budget. In addition, similarity analysis and numerical simulation have also been conducted for this wake study. A focus of the research has been to isolate the effects of both pressure gradient and initial wake asymmetry on the wake development. Experimental results reveal that the pressure gradient has a tremendous influence on the wake development, despite the relatively modest pressure gradients imposed. For a given pressure gradient, the development of an initially asymmetric wake is different from the initially symmetric wake. An explicit similarity solution for the shape parameters of the symmetric wake is obtained and agrees with the experimental results. The turbulent kinetic energy budget measurements of the symmetric wake demonstrate that except for the convection term, the imposed pressure gradient does not change the fundamental flow physics of turbulent kinetic energy transport. Based on the turbulent kinetic energy budget measurements, an approach to correct the bias error associated with the notoriously difficult dissipation estimate is proposed and validated through the comparison of the experimental estimate with a direct numerical simulation result.
Positivism and qualitative nursing research.
Paley, J
2001-01-01
Despite the hostility to positivism shown by qualitative methodologists in nursing, as in other disciplines, the epistemological and ontological instincts of qualitative researchers seem to coincide with those of the positivists, especially Bayesian positivists. This article suggests that positivists and qualitative researchers alike are pro-observation, proinduction, pro-plausibility and pro-subjectivity. They are also anti-cause, anti-realist, anti-explanation, anti-correspondence, anti-truth. In only one respect is there a significant difference between positivist and qualitative methodologists: most positivists have believed that, methodologically, the natural sciences and the social sciences are the same; most qualitative researchers are adamant that they are not. However, if positivism fails as a philosophy of the natural sciences (which it probably does), it might well succeed as a philosophy of the social sciences, just because there is a methodological watershed between the two. Reflex antagonism to positivism might therefore be a major obstacle to understanding the real reasons why qualitative research and the natural sciences are methodologically divergent; and less hostility on the part of qualitative nurse researchers might bring certain advantages in its wake.
NASA Technical Reports Server (NTRS)
Short, B. J.; Jacobsen, R. A.
1979-01-01
Simultaneous measurements were made of the upset responses experienced and the wake velocities encountered by an instrumented Learjet probe aircraft behind a Boeing 747 vortex-generating aircraft. The vortex-induced angular accelerations experienced could be predicted within 30% by a mathematical upset response model when the characteristics of the wake were well represented by the vortex model. The vortex model used in the present study adequately represented the wake flow field when the vortices dissipated symmetrically and only one vortex pair existed in the wake.
Long-term oscillations in the sleep/wake cycle of infants
NASA Astrophysics Data System (ADS)
Diambra, L.; Malta, C. P.; Capurro, A.
2009-11-01
The development of circadian sleep-wakefulness rhythm was investigated by a longitudinal study of six normal infants. We propose an entropy based measure for the sleep/wake cycle fragmentation. Our results confirm that the sleep/wake cycle fragmentation and the sleep/wake ratio decrease, while the circadian power increases during the maturation process of infants. In addition to these expected linear trends in the variables devised to quantify sleep consolidation, circadian power and sleep/wake ratio, we found that they present infradian rhythms in the monthly range.
A Laboratory Exercise Relating Soil Energy Budgets to Soil Temperature
ERIC Educational Resources Information Center
Koenig, Richard T.; Cerny-Koenig, Teresa; Kotuby-Amacher, Janice; Grossl, Paul R.
2008-01-01
Enrollment by students in degree programs other than traditional horticulture, agronomy, and soil science has increased in basic plant and soil science courses. In order to broaden the appeal of these courses to students from majors other than agriculture, we developed a hands-on laboratory exercise relating the basic concepts of a soil energy…
ERIC Educational Resources Information Center
Ensminger, David C.; Hoyt, Amy E.; Chandrasekhar, Arcot J.; McNulty, John A.
2013-01-01
We tested the hypothesis that medical students change their study strategies when transitioning from basic science courses to clerkships, and that their study practices are associated with performance scores. Factor scores for three approaches to studying (construction, rote, and review) generated from student (n = 150) responses to a…
Effects of Concept Mapping Instruction Approach on Students' Achievement in Basic Science
ERIC Educational Resources Information Center
Ogonnaya, Ukpai Patricia; Okafor, Gabriel; Abonyi, Okechukwu S.; Ugama, J. O.
2016-01-01
The study investigated the effects of concept mapping on students' achievement in basic science. The study was carried out in Ebonyi State of Nigeria. The study employed a quasi-experimental design. Specifically the pretest posttest non-equivalent control group research design was used. The sample was 122 students selected from two secondary…
ERIC Educational Resources Information Center
Willingham, Daniel T.
2017-01-01
Although most teacher education programs include instruction in the basic science of psychology, practicing teachers report that this preparation has low utility. Researchers have considered what sort of information from psychology about children's thinking, emotion, and motivation would be useful for teachers' practice. Here, I take a different…
ERIC Educational Resources Information Center
Jackson, Deborah C.; Johnson, Elizabeth D.
2013-01-01
The problem of students entering university lacking basic mathematical skills is a critical issue in the Australian higher-education sector and relevant globally. The Maths Skills programme at La Trobe University has been developed to address under preparation in the first-year science cohort in the absence of an institutional mathematics support…
ERIC Educational Resources Information Center
Kurki-Suonio, T.; Hakola, A.
2007-01-01
In the present paper, we propose an alternative, based on constructivism, to the conventional way of teaching basic physics courses at the university level. We call this approach "coherent teaching" and the underlying philosophy of teaching science and engineering "need-based learning". We have been applying this philosophy in…
Mathematics and Science Test Gaps. Pell Institute Fact Sheet. Updated
ERIC Educational Resources Information Center
Pell Institute for the Study of Opportunity in Higher Education, 2011
2011-01-01
Data is reported as percentages in 4th, 8th, and 12th grades based on proficiency in the subject ("Below Basic," "At Basic," "At Proficient", or "At Advanced"). "Low-income" on this data sheet means students who qualify for the National School Lunch Program. Both math and science data are from 2009…
ERIC Educational Resources Information Center
Lisk, Kristina; Agur, Anne M. R.; Woods, Nicole N.
2017-01-01
Several studies have shown that cognitive integration of basic and clinical sciences supports diagnostic reasoning in novices; however, there has been limited exploration of the ways in which educators can translate this model of mental activity into sound instructional strategies. The use of "self-explanation" during learning has the…
Long-Term Retention of Basic Science Knowledge: A Review Study
ERIC Educational Resources Information Center
Custers, Eugene J. F. M.
2010-01-01
In this paper, a review of long-term retention of basic science knowledge is presented. First, it is argued that retention of this knowledge has been a long-standing problem in medical education. Next, three types of studies are described that are employed in the literature to investigate long-term retention of knowledge in general. Subsequently,…
ERIC Educational Resources Information Center
Peterson, Janey C.; Czajkowski, Susan; Charlson, Mary E.; Link, Alissa R.; Wells, Martin T.; Isen, Alice M.; Mancuso, Carol A.; Allegrante, John P.; Boutin-Foster, Carla; Ogedegbe, Gbenga; Jobe, Jared B.
2013-01-01
Objective: To describe a mixed-methods approach to develop and test a basic behavioral science-informed intervention to motivate behavior change in 3 high-risk clinical populations. Our theoretically derived intervention comprised a combination of positive affect and self-affirmation (PA/SA), which we applied to 3 clinical chronic disease…
Intermediate SCDC Spanish Curricula Units. Science/Health, Unit 1, Kits 1-4, Teacher's Guide.
ERIC Educational Resources Information Center
Spanish Curricula Development Center, Miami Beach, FL.
Unified by the theme "our community", this unit, part of nine basic instructional units for intermediate level, reflects the observations of Mexican Americans, Puerto Ricans, and Cubans in various regions of the United States. Comprised of Kits 1-4, the unit extends the following basic and interpreted science processes: observing, communicating,…
10 CFR Appendix A to Part 605 - The Energy Research Program Office Descriptions
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 4 2013-01-01 2013-01-01 false The Energy Research Program Office Descriptions A Appendix... RESEARCH FINANCIAL ASSISTANCE PROGRAM Pt. 605, App. A Appendix A to Part 605—The Energy Research Program Office Descriptions 1. Basic Energy Sciences This program supports basic science research efforts in a...
10 CFR Appendix A to Part 605 - The Energy Research Program Office Descriptions
Code of Federal Regulations, 2014 CFR
2014-01-01
... 10 Energy 4 2014-01-01 2014-01-01 false The Energy Research Program Office Descriptions A Appendix... RESEARCH FINANCIAL ASSISTANCE PROGRAM Pt. 605, App. A Appendix A to Part 605—The Energy Research Program Office Descriptions 1. Basic Energy Sciences This program supports basic science research efforts in a...
10 CFR Appendix A to Part 605 - The Energy Research Program Office Descriptions
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 4 2012-01-01 2012-01-01 false The Energy Research Program Office Descriptions A Appendix... RESEARCH FINANCIAL ASSISTANCE PROGRAM Pt. 605, App. A Appendix A to Part 605—The Energy Research Program Office Descriptions 1. Basic Energy Sciences This program supports basic science research efforts in a...
10 CFR Appendix A to Part 605 - The Energy Research Program Office Descriptions
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 4 2011-01-01 2011-01-01 false The Energy Research Program Office Descriptions A Appendix... RESEARCH FINANCIAL ASSISTANCE PROGRAM Pt. 605, App. A Appendix A to Part 605—The Energy Research Program Office Descriptions 1. Basic Energy Sciences This program supports basic science research efforts in a...
Peer-Assisted Learning: Filling the Gaps in Basic Science Education for Preclinical Medical Students
ERIC Educational Resources Information Center
Sammaraiee, Yezen; Mistry, Ravi D.; Lim, Julian; Wittner, Liora; Deepak, Shantal; Lim, Gareth
2016-01-01
In contrast to peer-assisted learning (PAL) in clinical training, there is scant literature on the efficacy of PAL during basic medical sciences teaching for preclinical students. A group of senior medical students aimed to design and deliver clinically oriented small-group tutorials after every module in the preclinical curriculum at a United…
ERIC Educational Resources Information Center
Seeman, Jeffrey I.
2005-01-01
The chemical and physical properties of nicotine and its carboxylic acid salts found in tobacco provided as an interesting example to understand basic principles of complex science. The result showed that the experimental data used were inconsistent to the conclusion made, and the transfer of nicotine smoke from tobacco to smoke cannot be…
PRP Treatment Efficacy for Tendinopathy: A Review of Basic Science Studies
2016-01-01
Platelet-Rich Plasma (PRP) has been widely used in orthopaedic surgery and sport medicine to treat tendon injuries. However, the efficacy of PRP treatment for tendinopathy is controversial. This paper focuses on reviewing the basic science studies on PRP performed under well-controlled conditions. Both in vitro and in vivo studies describe PRP's anabolic and anti-inflammatory effects on tendons. While some clinical trials support these findings, others refute them. In this review, we discuss the effectiveness of PRP to treat tendon injuries with evidence presented in basic science studies and the potential reasons for the controversial results in clinical trials. Finally, we comment on the approaches that may be required to improve the efficacy of PRP treatment for tendinopathy. PMID:27610386
NASA Astrophysics Data System (ADS)
Jannati, E. D.; Setiawan, A.; Siahaan, P.; Rochman, C.
2018-05-01
This study aims to determine the description of virtual laboratory learning media development to improve science literacy skills of Mechanical Engineering students on the concept of basic Physics. Quasi experimental method was employed in this research. The participants of this research were first semester students of mechanical engineering in Majalengka University. The research instrument was readability test of instructional media. The results of virtual laboratory learning media readability test show that the average score is 78.5%. It indicates that virtual laboratory learning media development are feasible to be used in improving science literacy skill of Mechanical Engineering students in Majalengka University, specifically on basic Physics concepts of material measurement.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Banta, Robert M.; Pichugina, Yelena L.; Brewer, W. Alan
Wind turbine wakes in the atmosphere are three-dimensional (3D) and time dependent. An important question is how best to measure atmospheric wake properties, both for characterizing these properties observationally and for verification of numerical, conceptual, and physical (e.g., wind tunnel) models of wakes. Here a scanning, pulsed, coherent Doppler lidar is used to sample a turbine wake using 3D volume scan patterns that envelop the wake and simultaneously measure the inflow profile. The volume data are analyzed for quantities of interest, such as peak velocity deficit, downwind variability of the deficit, and downwind extent of the wake, in a mannermore » that preserves the measured data. For the case study presented here, in which the wake was well defined in the lidar data, peak deficits of up to 80% were measured 0.6-2 rotor diameters (D) downwind of the turbine, and the wakes extended more than 11D downwind. Temporal wake variability over periods of minutes and the effects of atmospheric gusts and lulls in the inflow are demonstrated in the analysis. Lidar scanning trade-offs important to ensuring that the wake quantities of interest are adequately sampled by the scan pattern, including scan coverage, number of scans per volume, data resolution, and scan-cycle repeat interval, are discussed.« less
Wind tunnel measurements for dispersion modelling of vehicle wakes
NASA Astrophysics Data System (ADS)
Carpentieri, Matteo; Kumar, Prashant; Robins, Alan
2012-12-01
Wind tunnel measurements downwind of reduced scale car models have been made to study the wake regions in detail, test the usefulness of existing vehicle wake models, and draw key information needed for dispersion modelling in vehicle wakes. The experiments simulated a car moving in still air. This is achieved by (i) the experimental characterisation of the flow, turbulence and concentration fields in both the near and far wake regions, (ii) the preliminary assessment of existing wake models using the experimental database, and (iii) the comparison of previous field measurements in the wake of a real diesel car with the wind tunnel measurements. The experiments highlighted very large gradients of velocities and concentrations existing, in particular, in the near-wake. Of course, the measured fields are strongly dependent on the geometry of the modelled vehicle and a generalisation for other vehicles may prove to be difficult. The methodology applied in the present study, although improvable, could constitute a first step towards the development of mathematical parameterisations. Experimental results were also compared with the estimates from two wake models. It was found that they can adequately describe the far-wake of a vehicle in terms of velocities, but a better characterisation in terms of turbulence and pollutant dispersion is needed. Parameterised models able to predict velocity and concentrations with fine enough details at the near-wake scale do not exist.
Aircraft Vortex Wake Descent and Decay under Real Atmospheric Effects
DOT National Transportation Integrated Search
1973-10-01
Aircraft vortex wake descent and decay in a real atmosphere is studied analytically. Factors relating to encounter hazard, wake generation, wake descent and stability, and atmospheric dynamics are considered. Operational equations for encounter hazar...
Analysis of Wake VAS Benefits Using ACES Build 3.2.1: VAMS Type 1 Assessment
NASA Technical Reports Server (NTRS)
Smith, Jeremy C.
2005-01-01
The FAA and NASA are currently engaged in a Wake Turbulence Research Program to revise wake turbulence separation standards, procedures, and criteria to increase airport capacity while maintaining or increasing safety. The research program is divided into three phases: Phase I near term procedural enhancements; Phase II wind dependent Wake Vortex Advisory System (WakeVAS) Concepts of Operations (ConOps); and Phase III farther term ConOps based on wake prediction and sensing. The Phase III Wake VAS ConOps is one element of the Virtual Airspace Modelling and Simulation (VAMS) program blended concepts for enhancing the total system wide capacity of the National Airspace System (NAS). This report contains a VAMS Program Type 1 (stand-alone) assessment of the expected capacity benefits of Wake VAS at the 35 FAA Benchmark Airports and determines the consequent reduction in delay using the Airspace Concepts Evaluation System (ACES) Build 3.2.1 simulator.
NASA Technical Reports Server (NTRS)
Lakshminarayana, B.; Davino, R.
1979-01-01
Pure tone noise, blade row vibrations, and aerodynamic losses are phenomena which are influenced by stator and IGV (inlet guide vane) blade wake production, decay, and interaction in an axial-flow compressor. The objective of this investigation is to develop a better understanding of the nature of stator and IGV blade wakes that are influenced by the presence of centrifugal forces due to flow curvature. A single sensor hot wire probe was employed to determine the three mean velocity components of stator and IGV wakes of a single stage compressor. These wake profiles indicated a varying decay rate of the tangential and axial wake velocity components and a wake profile similarity. An analysis, which predicts this trend, has been developed. The radial velocities are found to be appreciable in both IGV and the stator wakes.
Experimental evaluation of a flat wake theory for predicting rotor inflow-wake velocities
NASA Technical Reports Server (NTRS)
Wilson, John C.
1992-01-01
The theory for predicting helicopter inflow-wake velocities called flat wake theory was correlated with several sets of experimental data. The theory was developed by V. E. Baskin of the USSR, and a computer code known as DOWN was developed at Princeton University to implement the theory. The theory treats the wake geometry as rigid without interaction between induced velocities and wake structure. The wake structure is assumed to be a flat sheet of vorticity composed of trailing elements whose strength depends on the azimuthal and radial distributions of circulation on a rotor blade. The code predicts the three orthogonal components of flow velocity in the field surrounding the rotor. The predictions can be utilized in rotor performance and helicopter real-time flight-path simulation. The predictive capability of the coded version of flat wake theory provides vertical inflow patterns similar to experimental patterns.
Absolute instability of the Gaussian wake profile
NASA Technical Reports Server (NTRS)
Hultgren, Lennart S.; Aggarwal, Arun K.
1987-01-01
Linear parallel-flow stability theory has been used to investigate the effect of viscosity on the local absolute instability of a family of wake profiles with a Gaussian velocity distribution. The type of local instability, i.e., convective or absolute, is determined by the location of a branch-point singularity with zero group velocity of the complex dispersion relation for the instability waves. The effects of viscosity were found to be weak for values of the wake Reynolds number, based on the center-line velocity defect and the wake half-width, larger than about 400. Absolute instability occurs only for sufficiently large values of the center-line wake defect. The critical value of this parameter increases with decreasing wake Reynolds number, thereby indicating a shrinking region of absolute instability with decreasing wake Reynolds number. If backflow is not allowed, absolute instability does not occur for wake Reynolds numbers smaller than about 38.
Noreika, Valdas
2011-06-01
A number of differences between the dreams of schizophrenia patients and those of healthy participants have been linked to changes in waking life that schizophrenia may cause. This way, the "continuity hypothesis" has become a standard way to relate dreaming and waking experiences in schizophrenia. Nevertheless, some of the findings in dream literature are not compatible with the continuity hypothesis and suggest some other ways how dream content and waking experiences could interact. Conceptually, the continuity hypothesis could be sharpened into the "waking-to-dreaming" and the "dreaming-to-waking" hypotheses, whereas a less explored type of "discontinuity" could embrace the "compensated waking" and the "compensated dreaming" hypotheses. A careful consideration and empirical testing of each of those hypotheses may reveal a multiplicity of the ways how dreaming and waking life interact in schizophrenia. Copyright © 2010 Elsevier Inc. All rights reserved.
Wind Turbine Wake Variability in a Large Wind Farm, Observed by Scanning Lidar
NASA Astrophysics Data System (ADS)
Lundquist, J. K.; Xiaoxia, G.; Aitken, M.; Quelet, P. T.; Rana, J.; Rhodes, M. E.; St Martin, C. M.; Tay, K.; Worsnop, R.; Irvin, S.; Rajewski, D. A.; Takle, E. S.
2014-12-01
Although wind turbine wake modeling is critical for accurate wind resource assessment, operational forecasting, and wind plant optimization, verification of such simulations is currently constrained by sparse datasets taken in limited atmospheric conditions, often of single turbines in isolation. To address this knowledge gap, our team deployed a WINDCUBE 200S scanning lidar in a 300-MW operating wind farm as part of the CWEX-13 field experiment. The lidar was deployed ~2000 m from a row of four turbines, such that wakes from multiple turbines could be sampled with horizontal scans. Twenty minutes of every hour were devoted to horizontal scans at ½ degree resolution at six different elevation angles. Twenty-five days of data were collected, with wind speeds at hub height ranging from quiescent to 14 m/s, and atmospheric stability varying from unstable to strongly stable. The example scan in Fig. 1a shows wakes from a row of four turbines propagating to the northwest. This extensive wake dataset is analyzed based on the quantitative approach of Aitken et al. (J. Atmos. Ocean. Technol. 2014), who developed an automated wake detection algorithm to characterize wind turbine wakes from scanning lidar data. We have extended the Aitken et al. (2014) method to consider multiple turbines in a single scan in order to classify the large numbers of wakes observed in the CWEX-13 dataset (Fig. 1b) during southerly flow conditions. The presentation will explore the variability of wake characteristics such as the velocity deficit and the wake width. These characteristics vary with atmospheric stability, atmospheric turbulence, and inflow wind speed. We find that the strongest and most persistent wakes occur at low to moderate wind speeds (region 2 of the turbine power curve) in stable conditions. We also present evidence that, in stable conditions with strong changes of wind direction with height, wakes propagate in different directions at different elevations above the surface. Finally, we compare characteristics of wakes at the outside of the row of turbines to wakes from turbines in the interior of the row, quantifying how wakes from outer turbines erode faster than those from interior.
Rotor boundary layer development with inlet guide vane (IGV) wake impingement
NASA Astrophysics Data System (ADS)
Jia, Lichao; Zou, Tengda; Zhu, Yiding; Lee, Cunbiao
2018-04-01
This paper examines the transition process in a boundary layer on a rotor blade under the impingement of an inlet guide vane wake. The effects of wake strengths and the reduced frequency on the unsteady boundary layer development on a low-speed axial compressor were investigated using particle image velocimetry. The measurements were carried out at two reduced frequencies (fr = fIGVS0/U2i, fr = 1.35, and fr = 0.675) with the Reynolds number, based on the blade chord and the isentropic inlet velocity, being 97 500. At fr = 1.35, the flow separated at the trailing edge when the wake strength was weak. However, the separation was almost totally suppressed as the wake strength increased. For the stronger wake, both the wake's high turbulence and the negative jet behavior of the wake dominated the interaction between the unsteady wake and the separated boundary layer on the suction surface of the airfoil. The boundary layer displacement thickened first due to the negative jet effect. Then, as the disturbances developed underneath the wake, the boundary layer thickness reduced gradually. The high disturbance region convected downstream at a fraction of the free-stream velocity and spread in the streamwise direction. The separation on the suction surface was suppressed until the next wake's arrival. Because of the long recovery time at fr = 0.675, the boundary layer thickened gradually as the wake convected further downstream and finally separated due to the adverse pressure gradient. The different boundary layer states in turn affected the development of disturbances.
Dissipation of turbulence in the wake of a wind turbine
NASA Astrophysics Data System (ADS)
Lundquist, J. K.; Bariteau, L.
2013-12-01
The wake of a wind turbine is characterized by increased turbulence and decreased wind speed. Turbines are generally deployed in large groups in wind farms, and so the behavior of an individual wake as it merges with other wakes and propagates downwind is of great importance in assessing wind farm power production as well as impacts of wind energy deployment on local and regional environments. The rate of turbulence dissipation in the wake quantifies the wake behavior as it propagates. In situ field measurements of turbulence dissipation rate in the wake of wind turbines have not been previously collected although correct modeling of dissipation rate is required for accurate simulations of wake evolution. In Fall 2012, we collected in situ measurements of winds and turbulence dissipation from the wake region of a multi-MW turbine, using the University of Colorado at Boulder's Tethered Lifting System (TLS). The TLS is a unique state-of-the-art tethersonde, proven in numerous boundary-layer field experiments to be able to measure turbulence kinetic energy dissipation rates. Ambient flow measurements were provided from sonic anemometers on a meteorological tower located upwind of the turbine, from a profiling lidar upwind, and from a scanning lidar measuring both inflow to and wake from the turbine. Measurements collected within the wake indicate that dissipation rates are higher in the turbine wake than in the ambient flow. Profiles of dissipation and turbulence throughout the rotor disk suggest that dissipation peaks near the hub height of the turbine. Suggestions for incorporating this information into wind turbine modeling approaches will be provided.
NASA Astrophysics Data System (ADS)
Li, XiaoMing; Chi, Lequan; Chen, Xueen; Ren, YongZheng; Lehner, Susanne
2014-08-01
A TerraSAR-X (TS-X) Synthetic Aperture Radar (SAR) image acquired at the East China Sea offshore wind farm presents distinct wakes at a kilometer scale on the lee of the wind turbines. The presumption was that these wakes were caused by wind movement around turbine blades. However, wind analysis using spaceborne radiometer data, numerical weather prediction, and in situ measurements suggest that the prevailing wind direction did not align with the wakes. By analyzing measurement at the tidal gauge station and modeling of the tidal current field, these trailing wakes are interpreted to have formed when a strong tidal current impinged on the cylindrical monopiles of the wind turbines. A numerical simulation was further conducted to reproduce the tidal current wake under such conditions. Comparison of the simulated surface velocity in the wake region with the TS-X sea surface backscatter intensity shows a similar trend. Consequently, turbulence intensity (T.I.) of the tidal current wakes over multiple piles is studied using the TS-X observation. It is found that the T.I. has a logarithmic relation with distance. Furthermore, another case study showing wakes due to wind movement around turbine blades is presented to discuss the differences in the tidal current wakes and wind turbine wakes. The conclusion is drawn that small-scale wakes formed by interaction of the tidal current and the turbine piles could be also imaged by SAR when certain conditions are satisfied. The study is anticipated to draw more attentions to the impacts of offshore wind foundations on local hydrodynamic field.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pierce, Eric M.; Freshley, Mark D.; Hubbard, Susan S.
In this report, we start by examining previous efforts at linking science and DOE EM research with cleanup activities. Many of these efforts were initiated by creating science and technology roadmaps. A recurring feature of successfully implementing these roadmaps into EM applied research efforts and successful cleanup is the focus on integration. Such integration takes many forms, ranging from combining information generated by various scientific disciplines, to providing technical expertise to facilitate successful application of novel technology, to bringing the resources and creativity of many to address the common goal of moving EM cleanup forward. Successful projects identify and focusmore » research efforts on addressing the problems and challenges that are causing “failure” in actual cleanup activities. In this way, basic and applied science resources are used strategically to address the particular unknowns that are barriers to cleanup. The brief descriptions of the Office of Science basic (Environmental Remediation Science Program [ERSP]) and EM’s applied (Groundwater and Soil Remediation Program) research programs in subsurface science provide context to the five “crosscutting” themes that have been developed in this strategic planning effort. To address these challenges and opportunities, a tiered systematic approach is proposed that leverages basic science investments with new applied research investments from the DOE Office of Engineering and Technology within the framework of the identified basic science and applied research crosscutting themes. These themes are evident in the initial portfolio of initiatives in the EM groundwater and soil cleanup multi-year program plan. As stated in a companion document for tank waste processing (Bredt et al. 2008), in addition to achieving its mission, DOE EM is experiencing a fundamental shift in philosophy from driving to closure to enabling the long-term needs of DOE and the nation.« less
Evolution of Rotor Wake in Swirling Flow
NASA Technical Reports Server (NTRS)
El-Haldidi, Basman; Atassi, Hafiz; Envia, Edmane; Podboy, Gary
2000-01-01
A theory is presented for modeling the evolution of rotor wakes as a function of axial distance in swirling mean flows. The theory, which extends an earlier work to include arbitrary radial distributions of mean swirl, indicates that swirl can significantly alter the wake structure of the rotor especially at large downstream distances (i.e., for moderate to large rotor-stator spacings). Using measured wakes of a representative scale model fan stage to define the mean swirl and initial wake perturbations, the theory is used to predict the subsequent evolution of the wakes. The results indicate the sensitivity of the wake evolution to the initial profile and the need to have complete and consistent initial definition of both velocity and pressure perturbations.
NASA Technical Reports Server (NTRS)
Wright, K. H., Jr.; Stone, N. H.; Samir, U.
1983-01-01
In this review attention is called to basic phenomena and physical processes involved in the expansion of a plasma into a vacuum, or the expansion of a plasma into a more tenuous plasma, in particular the fact that upon the expansion, ions are accelerated and reach energies well above their thermal energy. Also, in the process of the expansion a rarefaction wave propagates into the ambient plasma, an ion front moves into the expansion volume, and discontinuities in plasma parameters occur. The physical processes which cause the above phenomena are discussed, and their possible application is suggested for the case of the distribution of ions and electrons (hence plasma potential and electric fields) in the wake region behind artificial and natural obstacles moving supersonically in a rarefied space plasma. To illustrate this, some in situ results are reexamined. Directions for future work in this area via the utilization of the Space Shuttle and laboratory work are also mentioned.
Big Bang Day: 5 Particles - 2. The Quark
None
2017-12-09
Simon Singh looks at the stories behind the discovery of 5 of the universe's most significant subatomic particles: the Electron, the Quark, the Anti-particle, the Neutrino and the "next particle". 2. The Quark "Three Quarks for Master Mark! Sure he hasn't got much of a bark." James Joyce's Finnegans Wake left its mark on modern physics when physicist Murray Gell Mann proposed this name for a group of hypothetical subatomic particles that were revealed in 1960 as the fundamental units of matter. Basic particles it seems are made up of even more basic units called quarks that make up 99.9% of visible material in the universe.. But why do we know so little about them? Quarks have never been seen as free particles but instead, inextricably bound together by the Strong Force that in turn holds the atomic nucleus together. This is the hardest of Nature's fundamental forces to crack, but recent theoretical advances, mean that the properties of the quark are at last being revealed.