Simulating synchrotron radiation in accelerators including diffuse and specular reflections

DOE PAGES

Dugan, G.; Sagan, D.

2017-02-24

An accurate calculation of the synchrotron radiation flux within the vacuum chamber of an accelerator is needed for a number of applications. These include simulations of electron cloud effects and the design of radiation masking systems. To properly simulate the synchrotron radiation, it is important to include the scattering of the radiation at the vacuum chamber walls. To this end, a program called synrad3d has been developed which simulates the production and propagation of synchrotron radiation using a collection of photons. Photons generated by a charged particle beam are tracked from birth until they strike the vacuum chamber wall wheremore » the photon is either absorbed or scattered. Both specular and diffuse scattering is simulated. If a photon is scattered, it is further tracked through multiple encounters with the wall until it is finally absorbed. This paper describes the synrad3d program, with a focus on the details of its scattering model, and presents some examples of the program’s use.« less

High brightness electron accelerator

DOEpatents

Sheffield, Richard L.; Carlsten, Bruce E.; Young, Lloyd M.

1994-01-01

A compact high brightness linear accelerator is provided for use, e.g., in a free electron laser. The accelerator has a first plurality of acclerating cavities having end walls with four coupling slots for accelerating electrons to high velocities in the absence of quadrupole fields. A second plurality of cavities receives the high velocity electrons for further acceleration, where each of the second cavities has end walls with two coupling slots for acceleration in the absence of dipole fields. The accelerator also includes a first cavity with an extended length to provide for phase matching the electron beam along the accelerating cavities. A solenoid is provided about the photocathode that emits the electons, where the solenoid is configured to provide a substantially uniform magnetic field over the photocathode surface to minimize emittance of the electons as the electrons enter the first cavity.

Systems and methods of varying charged particle beam spot size

DOEpatents

Chen, Yu-Jiuan

2014-09-02

Methods and devices enable shaping of a charged particle beam. A modified dielectric wall accelerator includes a high gradient lens section and a main section. The high gradient lens section can be dynamically adjusted to establish the desired electric fields to minimize undesirable transverse defocusing fields at the entrance to the dielectric wall accelerator. Once a baseline setting with desirable output beam characteristic is established, the output beam can be dynamically modified to vary the output beam characteristics. The output beam can be modified by slightly adjusting the electric fields established across different sections of the modified dielectric wall accelerator. Additional control over the shape of the output beam can be excreted by introducing intentional timing de-synchronization offsets and producing an injected beam that is not fully matched to the entrance of the modified dielectric accelerator.

Extreme Lagrangian acceleration in confined turbulent flow.

PubMed

Kadoch, Benjamin; Bos, Wouter J T; Schneider, Kai

2008-05-09

A Lagrangian study of two-dimensional turbulence for two different geometries, a periodic and a confined circular geometry, is presented to investigate the influence of solid boundaries on the Lagrangian dynamics. It is found that the Lagrangian acceleration is even more intermittent in the confined domain than in the periodic domain. The flatness of the Lagrangian acceleration as a function of the radius shows that the influence of the wall on the Lagrangian dynamics becomes negligible in the center of the domain, and it also reveals that the wall is responsible for the increased intermittency. The transition in the Lagrangian statistics between this region, not directly influenced by the walls, and a critical radius which defines a Lagrangian boundary layer is shown to be very sharp with a sudden increase of the acceleration flatness from about 5 to about 20.

Evaluating activation of the shielding walls of a treatment room using the Monte Carlo method

NASA Astrophysics Data System (ADS)

Lee, D.-Y.; Kim, J.-H.

2018-05-01

This study investigates the radiation activation process in a medical linear accelerator, which creates a photon beam with the energy acquired from accelerated electrons. The concrete shielding walls used in conjunction with a medical linear accelerator occupy the largest portion of facility decommissioning costs. Therefore, to evaluate the activation of the shielding wall, this study simulated the operation of a linear accelerator with high-energy photon beams (10, 15, and 20 MV). The results of the simulations showed that the high-energy photon beams produced a large number of neutrons in the areas around the linear accelerator head. Several radionuclides were identified, and their half-lives and radioactivity levels were calculated. Half-lives ranged from 2.62 hours to 3.68E+06 years, and the radioactivity levels of most of the radionuclides were found to satisfy their respective clearance requirements. These results indicate that photon beams of 15 MV or lower satisfy the clearance requirements for decommissioning a linear accelerator facility, whereas those of 20 MV or higher lie partially above the regulatory clearance levels.

Validation of cardiac accelerometer sensor measurements.

PubMed

Remme, Espen W; Hoff, Lars; Halvorsen, Per Steinar; Naerum, Edvard; Skulstad, Helge; Fleischer, Lars A; Elle, Ole Jakob; Fosse, Erik

2009-12-01

In this study we have investigated the accuracy of an accelerometer sensor designed for the measurement of cardiac motion and automatic detection of motion abnormalities caused by myocardial ischaemia. The accelerometer, attached to the left ventricular wall, changed its orientation relative to the direction of gravity during the cardiac cycle. This caused a varying gravity component in the measured acceleration signal that introduced an error in the calculation of myocardial motion. Circumferential displacement, velocity and rotation of the left ventricular apical region were calculated from the measured acceleration signal. We developed a mathematical method to separate translational and gravitational acceleration components based on a priori assumptions of myocardial motion. The accuracy of the measured motion was investigated by comparison with known motion of a robot arm programmed to move like the heart wall. The accuracy was also investigated in an animal study. The sensor measurements were compared with simultaneously recorded motion from a robot arm attached next to the sensor on the heart and with measured motion by echocardiography and a video camera. The developed compensation method for the varying gravity component improved the accuracy of the calculated velocity and displacement traces, giving very good agreement with the reference methods.

Improved animal models for testing gene therapy for atherosclerosis.

PubMed

Du, Liang; Zhang, Jingwan; De Meyer, Guido R Y; Flynn, Rowan; Dichek, David A

2014-04-01

Gene therapy delivered to the blood vessel wall could augment current therapies for atherosclerosis, including systemic drug therapy and stenting. However, identification of clinically useful vectors and effective therapeutic transgenes remains at the preclinical stage. Identification of effective vectors and transgenes would be accelerated by availability of animal models that allow practical and expeditious testing of vessel-wall-directed gene therapy. Such models would include humanlike lesions that develop rapidly in vessels that are amenable to efficient gene delivery. Moreover, because human atherosclerosis develops in normal vessels, gene therapy that prevents atherosclerosis is most logically tested in relatively normal arteries. Similarly, gene therapy that causes atherosclerosis regression requires gene delivery to an existing lesion. Here we report development of three new rabbit models for testing vessel-wall-directed gene therapy that either prevents or reverses atherosclerosis. Carotid artery intimal lesions in these new models develop within 2-7 months after initiation of a high-fat diet and are 20-80 times larger than lesions in a model we described previously. Individual models allow generation of lesions that are relatively rich in either macrophages or smooth muscle cells, permitting testing of gene therapy strategies targeted at either cell type. Two of the models include gene delivery to essentially normal arteries and will be useful for identifying strategies that prevent lesion development. The third model generates lesions rapidly in vector-naïve animals and can be used for testing gene therapy that promotes lesion regression. These models are optimized for testing helper-dependent adenovirus (HDAd)-mediated gene therapy; however, they could be easily adapted for testing of other vectors or of different types of molecular therapies, delivered directly to the blood vessel wall. Our data also supports the promise of HDAd to deliver long-term therapy from vascular endothelium without accelerating atherosclerotic disease.

Arc-driven rail accelerator research

NASA Technical Reports Server (NTRS)

Ray, Pradosh K.

1987-01-01

Arc-driven rail accelerator research is analyzed by considering wall ablation and viscous drag in the plasma. Plasma characteristics are evaluated through a simple fluid-mechanical analysis considering only wall ablation. By equating the energy dissipated in the plasma with the radiation heat loss, the average properties of the plasma are determined as a function of time and rate of ablation. Locations of two simultaneously accelerating arcs were determined by optical and magnetic probes and fron streak camera photographs. All three measurements provide consistent results.

Numerical Simulation of Dual-Mode Scramjet Combustors

NASA Technical Reports Server (NTRS)

Rodriguez, C. G.; Riggins, D. W.; Bittner, R. D.

2000-01-01

Results of a numerical investigation of a three-dimensional dual-mode scramjet isolator-combustor flow-field are presented. Specifically, the effect of wall cooling on upstream interaction and flow-structure is examined for a case assuming jet-to-jet symmetry within the combustor. Comparisons are made with available experimental wall pressures. The full half-duct for the isolator-combustor is then modeled in order to study the influence of side-walls. Large scale three-dimensionality is observed in the flow with massive separation forward on the side-walls of the duct. A brief review of convergence-acceleration techniques useful in dual-mode simulations is presented, followed by recommendations regarding the development of a reliable and unambiguous experimental data base for guiding CFD code assessments in this area.

Accelerated and Improved Differentiation of Retinal Organoids from Pluripotent Stem Cells in Rotating-Wall Vessel Bioreactors.

PubMed

DiStefano, Tyler; Chen, Holly Yu; Panebianco, Christopher; Kaya, Koray Dogan; Brooks, Matthew J; Gieser, Linn; Morgan, Nicole Y; Pohida, Tom; Swaroop, Anand

2018-01-09

Pluripotent stem cells can be differentiated into 3D retinal organoids, with major cell types self-patterning into a polarized, laminated architecture. In static cultures, organoid development may be hindered by limitations in diffusion of oxygen and nutrients. Herein, we report a bioprocess using rotating-wall vessel (RWV) bioreactors to culture retinal organoids derived from mouse pluripotent stem cells. Organoids in RWV demonstrate enhanced proliferation, with well-defined morphology and improved differentiation of neurons including ganglion cells and S-cone photoreceptors. Furthermore, RWV organoids at day 25 (D25) reveal similar maturation and transcriptome profile as those at D32 in static culture, closely recapitulating spatiotemporal development of postnatal day 6 mouse retina in vivo. Interestingly, however, retinal organoids do not differentiate further under any in vitro condition tested here, suggesting additional requirements for functional maturation. Our studies demonstrate that bioreactors can accelerate and improve organoid growth and differentiation for modeling retinal disease and evaluation of therapies. Published by Elsevier Inc.

Effects of spatial gradients in thermophysical properties on the topology of turbulence in heated channel flow of supercritical fluids

NASA Astrophysics Data System (ADS)

Azih, Chukwudi; Yaras, Metin I.

2018-01-01

The current literature suggests that large spatial gradients of thermophysical properties, which occur in the vicinity of the pseudo-critical thermodynamic state, may result in significant variations in forced-convection heat transfer rates. Specifically, these property gradients induce inertia- and buoyancy-driven phenomena that may enhance or deteriorate the turbulence-dominated heat convection process. Through direct numerical simulations, the present study investigates the role of coherent flow structures in channel geometries for non-buoyant and buoyant flows of supercritical water, with buoyant configurations involving wall-normal oriented gravitational acceleration and downstream-oriented gravitational acceleration. This sequence of simulations enables the evaluation of the relative contributions of inertial and buoyancy phenomena to heat transfer variations. In these simulations, the state of the working fluid is in the vicinity of the pseudo-critical point. The uniform wall heat flux and the channel mass flux are specified such that the heat to mass flux ratio is 3 kJ/kg, with an inflow Reynolds number of 12 000 based on the channel hydraulic diameter, the area-averaged inflow velocity, and fluid properties evaluated at the bulk temperature and pressure of the inflow plane. In the absence of buoyancy forces, notable reductions in the density and viscosity in close proximity of the heated wall are observed to promote generation of small-scale vortices, with resultant breakdown into smaller scales as they interact with preexisting larger near-wall vortices. This interaction results in a reduction in the overall thermal mixing at particular wall-normal regions of the channel. Under the influence of wall-normal gravitational acceleration, the wall-normal density gradients are noted to enhance ejection motions due to baroclinic vorticity generation on the lower wall, thus providing additional wall-normal thermal mixing. Along the upper wall, the same mechanism generates streamwise vorticity of the opposing sense of rotation in the close vicinity to the respective legs of the hairpin vortices causing a net reduction in thermal mixing. Finally, in the case of downstream-oriented gravitational acceleration, baroclinic vorticity generation as per spanwise density gradients causes additional wall-normal thermal mixing by promoting larger-scale ejection and sweep motions.

An Experimental Study of a Low-Jitter Pulsed Electromagnetic Plasma Accelerator

NASA Technical Reports Server (NTRS)

Thio, Y. C. Francis; Lee, Michael; Eskridge, Richard; Smith, James; Martin, Adam; Rodgers, Stephen L. (Technical Monitor)

2001-01-01

An experimental plasma accelerator for a variety of applications under development at the NASA Marshall Space Flight Center is described. The accelerator is a pulsed plasma thruster and has been tested experimentally and plasma jet velocities of approximately 50 kilometers per second have been obtained. The plasma jet structure has been photographed with 10 ns exposure times to reveal a stable and repeatable plasma structure. Data for velocity profile information has been obtained using light pipes embedded in the gun walls to record the plasma transit at various barrel locations. Preliminary spatially resolved spectral data and magnetic field probe data are also presented. A high speed triggering system has been developed and tested as a means of reducing the gun "jitter". This jitter has been characterized and future work for second generation "ultra-low jitter" gun development is identified.

Progress In Plasma Accelerator Development for Dynamic Formation of Plasma Liners

NASA Technical Reports Server (NTRS)

Thio, Y. C. Francis; Eskridge, Richard; Martin, Adam; Smith, James; Lee, Michael; Cassibry, Jason T.; Griffin, Steven; Rodgers, Stephen L. (Technical Monitor)

2002-01-01

An experimental plasma accelerator for magnetic target fusion (MTF) applications under development at the NASA Marshall Space Flight Center is described. The accelerator is a coaxial pulsed plasma thruster (Figure 1). It has been tested experimentally and plasma jet velocities of approx.50 km/sec have been obtained. The plasma jet has been photographed with 10-ns exposure times to reveal a stable and repeatable plasma structure (Figure 2). Data for velocity profile information has been obtained using light pipes and magnetic probes embedded in the gun walls to record the plasma and current transit respectively at various barrel locations. Preliminary spatially resolved spectral data and magnetic field probe data are also presented. A high speed triggering system has been developed and tested as a means of reducing the gun "jitter". This jitter is being characterized and future work for second generation "ultra-low jitter" gun development is being identified.

Plasma Accelerator Development for Dynamic Formation of Plasma Liners: A Status Report

NASA Technical Reports Server (NTRS)

Thio, Y. C. Francis; Eskridge, Richard; Martin, Adam; Smith, James; Lee, Michael; Rodgers, Stephen L. (Technical Monitor)

2001-01-01

An experimental plasma accelerator for magnetic target fusion (MTF) applications under development at the NASA Marshall Space Flight Center is described. The accelerator is a pulsed plasma thruster and has been tested experimentally and plasma jet velocities of approximately 50 km/sec have been obtained. The plasma jet structure has been photographed with 10 ns exposure times to reveal a stable and repeatable plasma structure. Data for velocity profile information has been obtained using light pipes embedded in the gun walls to record the plasma transit at various barrel locations. Preliminary spatially resolved spectral data and magnetic field probe data are also presented. A high speed triggering system has been developed and tested as a means of reducing the gun "jitter". This jitter is being characterized and future work for second generation "ultra-low jitter" gun development is being identified.

Accelerated aortic imaging using small field of view imaging and electrocardiogram-triggered quadruple inversion recovery magnetization preparation.

PubMed

Peel, Sarah A; Hussain, Tarique; Cecelja, Marina; Abbas, Abeera; Greil, Gerald F; Chowienczyk, Philip; Spector, Tim; Smith, Alberto; Waltham, Matthew; Botnar, Rene M

2011-11-01

To accelerate and optimize black blood properties of the quadruple inversion recovery (QIR) technique for imaging the abdominal aortic wall. QIR inversion delays were optimized for different heart rates in simulations and phantom studies by minimizing the steady state magnetization of blood for T(1) = 100-1400 ms. To accelerate and improve black blood properties of aortic vessel wall imaging, the QIR prepulse was combined with zoom imaging and (a) "traditional" and (b) "trailing" electrocardiogram (ECG) triggering. Ten volunteers were imaged pre- and post-contrast administration using a conventional ECG-triggered double inversion recovery (DIR) and the two QIR implementations in combination with a zoom-TSE readout. The QIR implemented with "trailing" ECG-triggering resulted in consistently good blood suppression as the second inversion delay was timed during maximum systolic flow in the aorta. The blood signal-to-noise ratio and vessel wall to blood contrast-to-noise ratio, vessel wall sharpness, and image quality scores showed a statistically significant improvement compared with the traditional QIR implementation with and without ECG-triggering. We demonstrate that aortic vessel wall imaging can be accelerated with zoom imaging and that "trailing" ECG-triggering improves black blood properties of the aorta which is subject to motion and variable blood flow during the cardiac cycle. Copyright © 2011 Wiley Periodicals, Inc.

Visual evidence of suppressing the ion and electron energy loss on the wall in Hall thrusters

NASA Astrophysics Data System (ADS)

Ding, Yongjie; Peng, Wuji; Sun, Hezhi; Wei, Liqiu; Zeng, Ming; Wang, Fufeng; Yu, Daren

2017-03-01

A method of pushing down magnetic field with two permanent magnetic rings is proposed in this paper. It can realize ionization in a channel and acceleration outside the channel. The wall will only suffer from the bombardment of low-energy ions and electrons, which can effectively reduce channel erosion and extend the operational lifetime of thrusters. Furthermore, there is no additional power consumption of coils, which improves the efficiency of systems. We show here the newly developed 200 W no wall-loss Hall thruster (NWLHT-200) that applies the method of pushing down magnetic field with two permanent magnetic rings; the visual evidence we obtained preliminarily confirms the feasibility that the proposed method can realize discharge without wall energy loss or erosion of Hall thrusters.

A self-consistent view on plasma-neutral interaction near a wall: plasma acceleration by momentum removal and heating by cold walls

NASA Astrophysics Data System (ADS)

van Rooij, Gerard; den Harder, Niek; Minea, Teofil; Shumack, Amy; de Blank, H.; Plasma Physics Team

2014-10-01

In plasma physics, material walls are generally regarded as perfect sinks for charged particles and their energy. A special case arises when the wall efficiently reflects the neutralized plasma particles (with a significant portion of their kinetic energy) and at the same time the upstream plasma is of sufficiently high density to yield strong neutral-ion coupling (i.e. reflected energy and momentum will not escape from the plasma). Under these conditions, plasma-surface interaction will feedback to the upstream plasma and a self-consistent view on the coupling between plasma and neutrals is required for correct prediction of plasma conditions and plasma-surface interaction. Here, an analytical and numerical study of the fluid equations is combined with experiments (in hydrogen and argon) to construct such a self-consistent view. It shows how plasma momentum removal builds up upstream pressure and causes plasma acceleration towards the wall. It also shows how energy reflection causes plasma heating, which recycles part of the reflected power to the wall and induces additional flow acceleration due to local sound speed increase. The findings are relevant as generic textbook example and are at play in the boundary plasma of fusion devices.

Andreas Acrivos Dissertation Award Talk: Modeling drag forces and velocity fluctuations in wall-bounded flows at high Reynolds numbers

NASA Astrophysics Data System (ADS)

Yang, Xiang

2017-11-01

The sizes of fluid motions in wall-bounded flows scale approximately as their distances from the wall. At high Reynolds numbers, resolving near-wall, small-scale, yet momentum-transferring eddies are computationally intensive, and to alleviate the strict near-wall grid resolution requirement, a wall model is usually used. The wall model of interest here is the integral wall model. This model parameterizes the near-wall sub-grid velocity profile as being comprised of a linear inner-layer and a logarithmic meso-layer with one additional term that accounts for the effects of flow acceleration, pressure gradients etc. We use the integral wall model for wall-modeled large-eddy simulations (WMLES) of turbulent boundary layers over rough walls. The effects of rough-wall topology on drag forces are investigated. A rough-wall model is then developed based on considerations of such effects, which are now known as mutual sheltering among roughness elements. Last, we discuss briefly a new interpretation of the Townsend attached eddy hypothesis-the hierarchical random additive process model (HRAP). The analogy between the energy cascade and the momentum cascade is mathematically formal as HRAP follows the multi-fractal formulism, which was extensively used for the energy cascade.

Enhanced dielectric-wall linear accelerator

DOEpatents

Sampayan, S.E.; Caporaso, G.J.; Kirbie, H.C.

1998-09-22

A dielectric-wall linear accelerator is enhanced by a high-voltage, fast e-time switch that includes a pair of electrodes between which are laminated alternating layers of isolated conductors and insulators. A high voltage is placed between the electrodes sufficient to stress the voltage breakdown of the insulator on command. A light trigger, such as a laser, is focused along at least one line along the edge surface of the laminated alternating layers of isolated conductors and insulators extending between the electrodes. The laser is energized to initiate a surface breakdown by a fluence of photons, thus causing the electrical switch to close very promptly. Such insulators and lasers are incorporated in a dielectric wall linear accelerator with Blumlein modules, and phasing is controlled by adjusting the length of fiber optic cables that carry the laser light to the insulator surface. 6 figs.

Enhanced dielectric-wall linear accelerator

DOEpatents

Sampayan, Stephen E.; Caporaso, George J.; Kirbie, Hugh C.

1998-01-01

A dielectric-wall linear accelerator is enhanced by a high-voltage, fast e-time switch that includes a pair of electrodes between which are laminated alternating layers of isolated conductors and insulators. A high voltage is placed between the electrodes sufficient to stress the voltage breakdown of the insulator on command. A light trigger, such as a laser, is focused along at least one line along the edge surface of the laminated alternating layers of isolated conductors and insulators extending between the electrodes. The laser is energized to initiate a surface breakdown by a fluence of photons, thus causing the electrical switch to close very promptly. Such insulators and lasers are incorporated in a dielectric wall linear accelerator with Blumlein modules, and phasing is controlled by adjusting the length of fiber optic cables that carry the laser light to the insulator surface.

EFFECTOF ISOLATION WALL USING SCRAP TIRE ON GROUND VIBRATION REDUCTION

NASA Astrophysics Data System (ADS)

Kashimoto, Takahiko; Kashimoto, Yusuke; Hayakawa, Kiyoshi; Matsui, Tamotsu; Fujimoto, Hiroaki

Some countermeasure methods against the environmental ground vibration caused by some traffic vibrations have been proposed so far. The authors have developed a new type ground vibration isolation wall using scrap tire, and evaluated its effectiveness on the ground vibration reduction by full scale field tests. In this paper, the authors discussed and examined the effectiveness of the developed countermeasure method by two field tests. The one concerns on the effect of scrap tire as soft material of vibration isolation wall, and the other on the effect of the developed countermeasure method practically applied in a residential area close to monorail traffic. As the results, it was elucidated that the ground vibration of 2-3 dB was reduced in case of two times volume of the soft material, the conversion ratio of the vibration energy of the soft material to the kinetic energy was higher than that of the core material of PHC pile, the vibration acceleration of 0.19 - 1.26 gal was reduced by the developed countermeasure method in case of the monorail traffic, and the vibration reduction measured behind the isolation wall agreed well with the proposed theoretical value, together with confirming the effectiveness of the ground vibration isolation wall using scrap tire as the countermeasure method against the environmental ground vibration.

A magnetostrictive acceleration sensor for registration of chest wall displacements

NASA Astrophysics Data System (ADS)

Kaniusas, E.; Mehnen, L.; Krell, C.; Pfützner, H.

2000-06-01

The present study concerns a novel acceleration sensor built up using a bimetallic strip with one freely oscillating end. The strip consists of a magnetostrictive amorphous ribbon glued on a nonmagnetic metal ribbon. The sensor's effectiveness is demonstrated for the case of chest wall displacements as resulting from cardiorespiratory activity. The cheap and easy-to-handle novel sensor offers multiple information on the so-called sleep apnea syndrome.

Study of coherent structures of turbulence with large wall-normal gradients in thermophysical properties using direct numerical simulation

NASA Astrophysics Data System (ADS)

Reinink, Shawn K.; Yaras, Metin I.

2015-06-01

Forced-convection heat transfer in a heated working fluid at a thermodynamic state near its pseudocritical point is poorly predicted by correlations calibrated with data at subcritical temperatures and pressures. This is suggested to be primarily due to the influence of large wall-normal thermophysical property gradients that develop in proximity of the pseudocritical point on the concentration of coherent turbulence structures near the wall. The physical mechanisms dominating this influence remain poorly understood. In the present study, direct numerical simulation is used to study the development of coherent vortical structures within a turbulent spot under the influence of large wall-normal property gradients. A turbulent spot rather than a fully turbulent boundary layer is used for the study, for the coherent structures of turbulence in a spot tend to be in a more organized state which may allow for more effective identification of cause-and-effect relationships. Large wall-normal gradients in thermophysical properties are created by heating the working fluid which is near the pseudocritical thermodynamic state. It is found that during improved heat transfer, wall-normal gradients in density accelerate the growth of the Kelvin-Helmholtz instability mechanism in the shear layer enveloping low-speed streaks, causing it to roll up into hairpin vortices at a faster rate. It is suggested that this occurs by the baroclinic vorticity generation mechanism which accelerates the streamwise grouping of vorticity during shear layer roll-up. The increased roll-up frequency leads to reduced streamwise spacing between hairpin vortices in wave packets. The density gradients also promote the sinuous instability mode in low-speed streaks. The resulting oscillations in the streaks in the streamwise-spanwise plane lead to locally reduced spanwise spacing between hairpin vortices forming over adjacent low-speed streaks. The reduction in streamwise and spanwise spacing between hairpin vortices causes them to interact more frequently by merging together and by breaking apart into smaller turbulence structures.

Study of coherent structures of turbulence with large wall-normal gradients in thermophysical properties using direct numerical simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reinink, Shawn K.; Yaras, Metin I., E-mail: Metin.Yaras@carleton.ca

2015-06-15

Forced-convection heat transfer in a heated working fluid at a thermodynamic state near its pseudocritical point is poorly predicted by correlations calibrated with data at subcritical temperatures and pressures. This is suggested to be primarily due to the influence of large wall-normal thermophysical property gradients that develop in proximity of the pseudocritical point on the concentration of coherent turbulence structures near the wall. The physical mechanisms dominating this influence remain poorly understood. In the present study, direct numerical simulation is used to study the development of coherent vortical structures within a turbulent spot under the influence of large wall-normal propertymore » gradients. A turbulent spot rather than a fully turbulent boundary layer is used for the study, for the coherent structures of turbulence in a spot tend to be in a more organized state which may allow for more effective identification of cause-and-effect relationships. Large wall-normal gradients in thermophysical properties are created by heating the working fluid which is near the pseudocritical thermodynamic state. It is found that during improved heat transfer, wall-normal gradients in density accelerate the growth of the Kelvin-Helmholtz instability mechanism in the shear layer enveloping low-speed streaks, causing it to roll up into hairpin vortices at a faster rate. It is suggested that this occurs by the baroclinic vorticity generation mechanism which accelerates the streamwise grouping of vorticity during shear layer roll-up. The increased roll-up frequency leads to reduced streamwise spacing between hairpin vortices in wave packets. The density gradients also promote the sinuous instability mode in low-speed streaks. The resulting oscillations in the streaks in the streamwise-spanwise plane lead to locally reduced spanwise spacing between hairpin vortices forming over adjacent low-speed streaks. The reduction in streamwise and spanwise spacing between hairpin vortices causes them to interact more frequently by merging together and by breaking apart into smaller turbulence structures.« less

Virtual gap dielectric wall accelerator

DOEpatents

Caporaso, George James; Chen, Yu-Jiuan; Nelson, Scott; Sullivan, Jim; Hawkins, Steven A

2013-11-05

A virtual, moving accelerating gap is formed along an insulating tube in a dielectric wall accelerator (DWA) by locally controlling the conductivity of the tube. Localized voltage concentration is thus achieved by sequential activation of a variable resistive tube or stalk down the axis of an inductive voltage adder, producing a "virtual" traveling wave along the tube. The tube conductivity can be controlled at a desired location, which can be moved at a desired rate, by light illumination, or by photoconductive switches, or by other means. As a result, an impressed voltage along the tube appears predominantly over a local region, the virtual gap. By making the length of the tube large in comparison to the virtual gap length, the effective gain of the accelerator can be made very large.

Crunching Knowledge: The Coming Environment for the Information Specialist.

ERIC Educational Resources Information Center

Nelson, Milo

The adjustment of librarians to technological change has been difficult because they have been too close observers of the present at the expense of daydreaming about society's likely future. The brisk pace of business, industry, and Wall Street has been accelerated even more by developments in information technology and computer communications. A…

Strategies To Discover the Structural Components of Cyst and Oocyst Walls

PubMed Central

Bushkin, G. Guy; Chatterjee, Aparajita; Robbins, Phillips W.

2013-01-01

Cysts of Giardia lamblia and Entamoeba histolytica and oocysts of Toxoplasma gondii and Cryptosporidium parvum are the infectious and sometimes diagnostic forms of these parasites. To discover the structural components of cyst and oocyst walls, we have developed strategies based upon a few simple assumptions. Briefly, the most abundant wall proteins are identified by monoclonal antibodies or mass spectrometry. Structural components include a sugar polysaccharide (chitin for Entamoeba, β-1,3-linked glucose for Toxoplasma, and β-1,3-linked GalNAc for Giardia) and/or acid-fast lipids (Toxoplasma and Cryptosporidium). Because Entamoeba cysts and Toxoplasma oocysts are difficult to obtain, studies of walls of nonhuman pathogens (E. invadens and Eimeria, respectively) accelerate discovery. Biochemical methods to dissect fungal walls work well for cyst and oocyst walls, although the results are often unexpected. For example, echinocandins, which inhibit glucan synthases and kill fungi, arrest the development of oocyst walls and block their release into the intestinal lumen. Candida walls are coated with mannans, while Entamoeba cysts are coated in a dextran-like glucose polymer. Models for cyst and oocyst walls derive from their structural components and organization within the wall. Cyst walls are composed of chitin fibrils and lectins that bind chitin (Entamoeba) or fibrils of the β-1,3-GalNAc polymer and lectins that bind the polymer (Giardia). Oocyst walls of Toxoplasma have two distinct layers that resemble those of fungi (β-1,3-glucan in the inner layer) or mycobacteria (acid-fast lipids in the outer layer). Oocyst walls of Cryptosporidium have a rigid bilayer of acid-fast lipids and inner layer of oocyst wall proteins. PMID:24096907

Design of two-dimensional channels with prescribed velocity distributions along the channel walls

NASA Technical Reports Server (NTRS)

Stanitz, John D

1953-01-01

A general method of design is developed for two-dimensional unbranched channels with prescribed velocities as a function of arc length along the channel walls. The method is developed for both compressible and incompressible, irrotational, nonviscous flow and applies to the design of elbows, diffusers, nozzles, and so forth. In part I solutions are obtained by relaxation methods; in part II solutions are obtained by a Green's function. Five numerical examples are given in part I including three elbow designs with the same prescribed velocity as a function of arc length along the channel walls but with incompressible, linearized compressible, and compressible flow. One numerical example is presented in part II for an accelerating elbow with linearized compressible flow, and the time required for the solution by a Green's function in part II was considerably less than the time required for the same solution by relaxation methods in part I.

Suppressive effects of dietary EPA-rich fish oil on the degradation of elastin fibers in the aortic wall in nicotine-administered mice.

PubMed

Kugo, Hirona; Zaima, Nobuhiro; Onozato, Megumi; Miyamoto, Chie; Hashimoto, Keisuke; Yanagimoto, Kenichi; Moriyama, Tatsuya

2017-08-01

Abdominal aortic aneurysm (AAA) is a vascular disease involving gradual dilation of the abdominal aorta. Recent studies suggest that nicotine, which is a primary component in cigarette smoke, is closely associated with the development and rupture of an AAA. Nicotine accelerates AAA development through the weakening of the vascular wall by increasing oxidative stress and matrix metalloproteinase (MMP)-2 expression. However, little is known about preventing the AAA induced by nicotine. A non-surgical means of preventing the weakening of the vascular wall before the onset of AAA by functional food factors would be a valuable option over surgery. Fish oil is a functional food that is rich in n-3 polyunsaturated fatty acids that have an anti-inflammatory effect. In this study, we evaluated the effect of dietary fish oil on the weakening of the aortic wall due to nicotine administration in a mouse model. Histological analysis showed that the dietary fish oil suppressed the degradation of elastin fibers in the nicotine-administered mice. Additionally, the dietary fish oil suppressed the protein level of MMP-12, macrophage infiltration, and the oxidative stress in the vascular wall. These results suggest that fish oil could suppress the weakening of the vascular wall by suppressing the elastin fiber degradation caused by nicotine. By suppressing the nicotine induced weakening of the vascular wall, fish oil might help prevent the development of AAA.

Summary of SLAC's SEY Measurement On Flat Accelerator Wall Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Le Pimpec, F.; /PSI, Villigen /SLAC

The electron cloud effect (ECE) causes beam instabilities in accelerator structures with intense positively charged bunched beams. Reduction of the secondary electron yield (SEY) of the beam pipe inner wall is effective in controlling cloud formation. We summarize SEY results obtained from flat TiN, TiZrV and Al surfaces carried out in a laboratory environment. SEY was measured after thermal conditioning, as well as after low energy, less than 300 eV, particle exposure.

High spatial resolution measurements in a single stage ram accelerator

NASA Technical Reports Server (NTRS)

Hinkey, J. B.; Burnham, E. A.; Bruckner, A. P.

1992-01-01

High spatial resolution experimental tube wall pressure measurements of ram accelerator gas dynamic phenomena are presented in this paper. The ram accelerator is a ramjet-in-tube device which operates in a manner similar to that of a conventional ramjet. The projectile resembles the centerbody of a ramjet and travels supersonically through a tube filled with a combustible gaseous mixture, with the tube acting as the outer cowling. Pressure data are recorded as the projectile passes by sensors mounted in the tube wall at various locations along the tube. Utilization of special highly instrumented sections of tube has allowed the recording of gas dynamic phenomena with high resolution. High spatial resolution tube wall pressure data from the three regimes of propulsion studied to date (subdetonative, transdetonative, and superdetonative) in a single stage gas mixture are presented and reveal the three-dimensional character of the flow field induced by projectile fins and the canting of the fins and the canting of the projectile body relative to the tube wall. Also presented for comparison to the experimental data are calculations made with an inviscid, three-dimensional CFD code. The knowledge gained from these experiments and simulations is useful in understanding the underlying nature of ram accelerator propulsive regimes, as well as assisting in the validation of three-dimensional CFD coded which model unsteady, chemically reactive flows.

The IBA Easy-E-Beam™ Integrated Processing System

NASA Astrophysics Data System (ADS)

Cleland, Marshall R.; Galloway, Richard A.; Lisanti, Thomas F.

2011-06-01

IBA Industrial Inc., (formerly known as Radiation Dynamics, Inc.) has been making high-energy and medium-energy, direct-current proton and electron accelerators for research and industrial applications for many years. Some industrial applications of high-power electron accelerators are the crosslinking of polymeric materials and products, such as the insulation on electrical wires, multi-conductor cable jackets, heat-shrinkable plastic tubing and film, plastic pipe, foam and pellets, the partial curing of rubber sheet for automobile tire components, and the sterilization of disposable medical devices. The curing (polymerization and crosslinking) of carbon and glass fiber-reinforced composite plastic parts, the preservation of foods and the treatment of waste materials are attractive possibilities for future applications. With electron energies above 1.0 MeV, the radiation protection for operating personnel is usually provided by surrounding the accelerator facility with thick concrete walls. With lower energies, steel and lead panels can be used, which are substantially thinner and more compact than the equivalent concrete walls. IBA has developed a series of electron processing systems called Easy-e-Beam™ for the medium energy range from 300 keV to 1000 keV. These systems include the shielding as an integral part of a complete radiation processing facility. The basic concepts of the electron accelerator, the product processing equipment, the programmable control system, the configuration of the radiation shielding and some performance characteristics are described in this paper.

Secondary electron emission from plasma processed accelerating cavity grade niobium

NASA Astrophysics Data System (ADS)

Basovic, Milos

Advances in the particle accelerator technology have enabled numerous fundamental discoveries in 20th century physics. Extensive interdisciplinary research has always supported further development of accelerator technology in efforts of reaching each new energy frontier. Accelerating cavities, which are used to transfer energy to accelerated charged particles, have been one of the main focuses of research and development in the particle accelerator field. Over the last fifty years, in the race to break energy barriers, there has been constant improvement of the maximum stable accelerating field achieved in accelerating cavities. Every increase in the maximum attainable accelerating fields allowed for higher energy upgrades of existing accelerators and more compact designs of new accelerators. Each new and improved technology was faced with ever emerging limiting factors. With the standard high accelerating gradients of more than 25 MV/m, free electrons inside the cavities get accelerated by the field, gaining enough energy to produce more electrons in their interactions with the walls of the cavity. The electron production is exponential and the electron energy transfer to the walls of a cavity can trigger detrimental processes, limiting the performance of the cavity. The root cause of the free electron number gain is a phenomenon called Secondary Electron Emission (SEE). Even though the phenomenon has been known and studied over a century, there are still no effective means of controlling it. The ratio between the electrons emitted from the surface and the impacting electrons is defined as the Secondary Electron Yield (SEY). A SEY ratio larger than 1 designates an increase in the total number of electrons. In the design of accelerator cavities, the goal is to reduce the SEY to be as low as possible using any form of surface manipulation. In this dissertation, an experimental setup was developed and used to study the SEY of various sample surfaces that were treated by different techniques. Specifically, this work provides the results of SEY from the plasma cleaned cavity grade niobium (Nb) samples. Pure niobium is currently the material of choice for the fabrication of Superconducting Radio Frequency (SRF) cavities. The effect of plasma processing with two different gases will be examined in two groups of samples. The first group of samples is made from cavity grade niobium. The second group of samples is made from the same material, but include a welded joint made by electron beam welding, since in niobium SRF cavities the peak electric and magnetic field are seen in close proximity to the welded joints. Both groups of samples will be exposed to nitrogen (N2) and a mixture of argon with oxygen (Ar/O2) plasma. It is the goal of this research to determine the SEY on these two groups of samples before and after plasma processing as a function of the energy of primary electrons. The SEY as a function of the angle of incidence of the primary electrons is tested on the samples treated with Ar/O2 plasma.

Ultra-high vacuum photoelectron linear accelerator

DOEpatents

Yu, David U.L.; Luo, Yan

2013-07-16

An rf linear accelerator for producing an electron beam. The outer wall of the rf cavity of said linear accelerator being perforated to allow gas inside said rf cavity to flow to a pressure chamber surrounding said rf cavity and having means of ultra high vacuum pumping of the cathode of said rf linear accelerator. Said rf linear accelerator is used to accelerate polarized or unpolarized electrons produced by a photocathode, or to accelerate thermally heated electrons produced by a thermionic cathode, or to accelerate rf heated field emission electrons produced by a field emission cathode.

Estimation of Metal Acceleration by an SF5 Containing Explosive

DTIC Science & Technology

1991-06-30

cylinder wall acceleration, the wall energies for the baseline composition and for the composition CW2 were calculated by three different methods : KSM, 6...computaticno! method to calculate the cylinder energies needed for comparison with expermental data, it was decided to compare data from three known methods ...detonation pressure given for the GAB method in Reference 8. They are E(6mm) = 0.1272 (Isp X density)1 .5 - 0.021, and E(l9mm) = 0.1580 (Isp x density) 1 .5

Highly efficient nonrigid motion‐corrected 3D whole‐heart coronary vessel wall imaging

PubMed Central

Atkinson, David; Henningsson, Markus; Botnar, Rene M.; Prieto, Claudia

2016-01-01

Purpose To develop a respiratory motion correction framework to accelerate free‐breathing three‐dimensional (3D) whole‐heart coronary lumen and coronary vessel wall MRI. Methods We developed a 3D flow‐independent approach for vessel wall imaging based on the subtraction of data with and without T2‐preparation prepulses acquired interleaved with image navigators. The proposed method corrects both datasets to the same respiratory position using beat‐to‐beat translation and bin‐to‐bin nonrigid corrections, producing coregistered, motion‐corrected coronary lumen and coronary vessel wall images. The proposed method was studied in 10 healthy subjects and was compared with beat‐to‐beat translational correction (TC) and no motion correction for the left and right coronary arteries. Additionally, the coronary lumen images were compared with a 6‐mm diaphragmatic navigator gated and tracked scan. Results No significant differences (P > 0.01) were found between the proposed method and the gated and tracked scan for coronary lumen, despite an average improvement in scan efficiency to 96% from 59%. Significant differences (P < 0.01) were found in right coronary artery vessel wall thickness, right coronary artery vessel wall sharpness, and vessel wall visual score between the proposed method and TC. Conclusion The feasibility of a highly efficient motion correction framework for simultaneous whole‐heart coronary lumen and vessel wall has been demonstrated. Magn Reson Med 77:1894–1908, 2017. © 2016 International Society for Magnetic Resonance in Medicine PMID:27221073

Magnetic Shielding of the Channel Walls in a Hall Plasma Accelerator

NASA Technical Reports Server (NTRS)

Mikellides, Ioannis G.; Katz, Ira; Hofer, Richard R.; Goebel, Dan M.; deGrys, Kristi; Mathers, Alex

2011-01-01

In a qualification life test of a Hall thruster it was found that the erosion of the acceleration channel practically stopped after approx 5,600 h. Numerical simulations using a two-dimensional axisymmetric plasma solver with a magnetic field-aligned mesh reveal that when the channel receded from its early-in-life to its steady-state configuration the following changes occurred near the wall: (1) reduction of the electric field parallel to the wall that prohibited ions from acquiring significant impact kinetic energy before entering the sheath, (2) reduction of the potential fall in the sheath that further diminished the total energy ions gained before striking the material, and (3) reduction of the ion number density that decreased the flux of ions to the wall. All these changes, found to have been induced by the magnetic field, constituted collectively an effective shielding of the walls from any significant ion bombardment. Thus, we term this process in Hall thrusters "magnetic shielding."

Assessment of fluctuating pressure gradient using acceleration spectra in near wall flows

NASA Astrophysics Data System (ADS)

Cadel, Daniel; Lowe, K. Todd

2015-11-01

Separation of contributions to the fluctuating acceleration from pressure gradient fluctuations and viscous shear fluctuations in the frequency domain is examined in a turbulent boundary layer. Past work leveraging turbulent accelerations for pressure gradient measurements has neglected the viscous shear term from the momentum equation--an invalid assumption in the case of near wall flows. The present study seeks to account for the influence of the viscous shear term and spectrally reject its contribution, which is thought to be concentrated at higher frequencies. Spectra of velocity and acceleration fluctuations in a flat plate, zero pressure gradient turbulent boundary layer at a momentum thickness Reynolds number of 7500 are measured using a spatially resolving three-component laser Doppler velocimeter. This canonical case data is applied for validation of the spectral approach for future application in more complex aerodynamic flows.

Development and application of new composite grouting material for sealing groundwater inflow and reinforcing wall rock in deep mine.

PubMed

Jinpeng, Zhang; Limin, Liu; Futao, Zhang; Junzhi, Cao

2018-04-04

With cement, bentonite, water glass, J85 accelerator, retarder and water as raw materials, a new composite grouting material used to seal groundwater inflow and reinforce wall rock in deep fractured rock mass was developed in this paper. Based on the reaction mechanism of raw material, the pumpable time, stone rate, initial setting time, plastic strength and unconfined compressive strength of multi-group proportion grouts were tested by orthogonal experiment. Then, the optimum proportion of composite grouting material was selected and applied to the grouting engineering for sealing groundwater inflow and reinforcing wall rock in mine shaft lining. The results show the mixing proportion of the maximum pumpable time, maximum stone rate and minimum initial setting time of grout are A K4 B K1 C K4 D K2 , A K3 B K1 C K1 D K4 and A K3 B K3 C K4 D K1 , respectively. The mixing proportion of the maximum plastic strength and unconfined compressive strength of grouts concretion bodies are A K1 B K1 C K1 D K3 and A K1 B K1 C K1 D K1 , respectively. Balanced the above 5 indicators overall and determined the optimum proportion of grouts: bentonite-cement ratio of 1.0, water-solid ratio of 3.5, accelerator content of 2.9% and retarder content of 1.45%. This new composite grouting material had good effect on the grouting engineering for sealing groundwater inflow and reinforcing wall rock in deep fractured rock mass.

Benchmark Calibration Tests Completed for Stirling Convertor Heater Head Life Assessment

NASA Technical Reports Server (NTRS)

Krause, David L.; Halford, Gary R.; Bowman, Randy R.

2005-01-01

A major phase of benchmark testing has been completed at the NASA Glenn Research Center (http://www.nasa.gov/glenn/), where a critical component of the Stirling Radioisotope Generator (SRG) is undergoing extensive experimentation to aid the development of an analytical life-prediction methodology. Two special-purpose test rigs subjected SRG heater-head pressure-vessel test articles to accelerated creep conditions, using the standard design temperatures to stay within the wall material s operating creep-response regime, but increasing wall stresses up to 7 times over the design point. This resulted in well-controlled "ballooning" of the heater-head hot end. The test plan was developed to provide critical input to analytical parameters in a reasonable period of time.

Recent developments in measurement and evaluation of FAC damage in power plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garud, Y.S.; Besuner, P.; Cohn, M.J.

1999-11-01

This paper describes some recent developments in the measurement and evaluation of flow-accelerated corrosion (FAC) damage in power plants. The evaluation focuses on data checking and smoothing to account for gross errors, noise, and uncertainty in the wall thickness measurements from ultrasonic or pulsed eddy-current data. Also, the evaluation method utilizes advanced regression analysis for spatial and temporal evolution of the wall loss, providing statistically robust predictions of wear rates and associated uncertainty. Results of the application of these new tools are presented for several components in actual service. More importantly, the practical implications of using these advances are discussedmore » in relation to the likely impact on the scope and effectiveness of FAC related inspection programs.« less

Effect of acoustic coupling on power-law flame acceleration in spherical confinement

NASA Astrophysics Data System (ADS)

Akkerman, V'yacheslav; Law, Chung K.

2013-01-01

A model describing acoustically-generated parametric instability in a spherical chamber is developed for quasi-one-dimensional, low-Mach number flames. We demonstrate how sound waves generated by a centrally-ignited, outwardly-propagating accelerating flamefront can be incorporated into an existing theory of self-similar flame acceleration in free space [V. Akkerman, C. K. Law, and V. Bychkov, "Self-similar accelerative propagation of expanding wrinkled flames and explosion triggering," Phys. Rev. E 83, 026305 (2011)], 10.1103/PhysRevE.83.026305. Being reflected from the chamber wall, flame-generated acoustics interact with the flamefront and the attendant hydrodynamic flamefront cellular instability. This in turn affects the subsequent flame morphology and propagation speed. It is shown that the acoustics modify the power-law flame acceleration, concomitantly facilitating or inhibiting the transition to detonation in confinement, which allows reconciliation of a discrepancy in experimental measurements of different groups.

Centrifugation causes adaptation of microfilaments: studies on the transport of statoliths in gravity sensing Chara rhizoids.

PubMed

Braun, M; Sievers, A

1993-01-01

The actin cytoskeleton is involved in the positioning of statoliths in tip growing Chara rhizoids. The balance between the acropetally acting gravity force and the basipetally acting net outcome of cytoskeletal force results in the dynamically stable position of the statoliths 10-30 micrometers above the cell tip. A change of the direction and/or the amount of one of these forces in a vertically growing rhizoid results in a dislocation of statoliths. Centrifugation was used as a tool to study the characteristics of the interaction between statoliths and microfilaments (MFs). Acropetal and basipetal accelerations up to 6.5 g were applied with the newly constructed slow-rotating-centrifuge-microscope (NIZEMI). Higher accelerations were applied by means of a conventional centrifuge, namely acropetally 10-200 g and basipetally 10-70 g. During acropetal accelerations (1.4-6g), statoliths were displaced to a new stable position nearer to the cell vertex (12-6.5 micrometers distance to the apical cell wall, respectively), but they did not sediment on the apical cell wall. The original position of the statoliths was reestablished within 30 s after centrifugation. Sedimentation of statoliths and reduction of the growth rates of the rhizoids were observed during acropetal accelerations higher than 50 g. When not only the amount but also the direction of the acceleration were changed in comparison to the natural condition, i.e., during basipetal accelerations (1.0-6.5 g), statoliths were displaced into the subapical zone (up to 90 micrometers distance to the apical cell wall); after 15-20 min the retransport of statoliths to the apex against the direction of acceleration started. Finally, the natural position in the tip was reestablished against the direction of continuous centrifugation. Retransport was observed during accelerations up to 70 g. Under the 1 g condition that followed the retransported statoliths showed an up to 5-fold increase in sedimentation time onto the lateral cell wall when placed horizontally. During basipetal centrifugations > or = 70 g all statoliths entered the basal vacuolar part of the rhizoid where they were cotransported in the streaming cytoplasm. It is concluded that the MF system is able to adapt to higher mass accelerations and that the MF system of the polarly growing rhizoid is polarly organized.

EXPERIMENTAL STUDY ON BEHAVIOR OF KENCHI BLOCK MASONRY WALL WITH THE SHAKING TABLE TEST DURING BY VIBRATION CHARACTERISTICS AND FAILURE MECHANISM

NASA Astrophysics Data System (ADS)

Ikemoto, Toshikazu; Mori, Masashi; Miyajima, Masakatsu; Hashimoto, Takao; Murata, Akira

There are many earthquake damages of kenchi block masonry wall. So, we carried out experimental studies on the collapse mechanism of kenchi block masonry wall during earthquake. From these experimental data, i.e. acceleration response magnification, displacement and soil pressure were found to destroy the central wall vibrations caused by the subsidence of the embankment.

The Resistive-Wall Instability in Multipulse Linear Induction Accelerators

DOE PAGES

Ekdahl, Carl

2017-05-01

The resistive-wall instability results from the Lorentz force on the beam due to the beam image charge and current. If the beam pipe is perfectly conducting, the electric force due to the image charge attracts the beam to the pipe wall, and the magnetic force due to the image current repels the beam from the wall. For a relativistic beam, these forces almost cancel, leaving a slight attractive force, which is easily overcome by external magnetic focusing. However, if the beam pipe is not perfectly conducting, the magnetic field due to the image current decays on a magnetic-diffusion time scale.more » If the beam pulse is longer than the magnetic diffusion time, the repulsion of the beam tail will be weaker than the repulsion of the beam head. In the absence of an external focusing force, this causes a head-to-tail sweep of the beam toward the wall. This instability is usually thought to be a concern only for long-pulse relativistic electron beams. However, with the advent of multipulse, high current linear induction accelerators, the possibility of pulse-to-pulse coupling of this instability should be investigated. Lastly, we have explored pulse-to-pulse coupling using the linear accelerator model for Dual Axis Radiography for Hydrodynamic Testing beam dynamics code, and we present the results of this paper.« less

The Resistive-Wall Instability in Multipulse Linear Induction Accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ekdahl, Carl

The resistive-wall instability results from the Lorentz force on the beam due to the beam image charge and current. If the beam pipe is perfectly conducting, the electric force due to the image charge attracts the beam to the pipe wall, and the magnetic force due to the image current repels the beam from the wall. For a relativistic beam, these forces almost cancel, leaving a slight attractive force, which is easily overcome by external magnetic focusing. However, if the beam pipe is not perfectly conducting, the magnetic field due to the image current decays on a magnetic-diffusion time scale.more » If the beam pulse is longer than the magnetic diffusion time, the repulsion of the beam tail will be weaker than the repulsion of the beam head. In the absence of an external focusing force, this causes a head-to-tail sweep of the beam toward the wall. This instability is usually thought to be a concern only for long-pulse relativistic electron beams. However, with the advent of multipulse, high current linear induction accelerators, the possibility of pulse-to-pulse coupling of this instability should be investigated. Lastly, we have explored pulse-to-pulse coupling using the linear accelerator model for Dual Axis Radiography for Hydrodynamic Testing beam dynamics code, and we present the results of this paper.« less

Dielectric-wall linear accelerator with a high voltage fast rise time switch that includes a pair of electrodes between which are laminated alternating layers of isolated conductors and insulators

DOEpatents

Caporaso, G.J.; Sampayan, S.E.; Kirbie, H.C.

1998-10-13

A dielectric-wall linear accelerator is improved by a high-voltage, fast rise-time switch that includes a pair of electrodes between which are laminated alternating layers of isolated conductors and insulators. A high voltage is placed between the electrodes sufficient to stress the voltage breakdown of the insulator on command. A light trigger, such as a laser, is focused along at least one line along the edge surface of the laminated alternating layers of isolated conductors and insulators extending between the electrodes. The laser is energized to initiate a surface breakdown by a fluence of photons, thus causing the electrical switch to close very promptly. Such insulators and lasers are incorporated in a dielectric wall linear accelerator with Blumlein modules, and phasing is controlled by adjusting the length of fiber optic cables that carry the laser light to the insulator surface. 12 figs.

Dielectric-wall linear accelerator with a high voltage fast rise time switch that includes a pair of electrodes between which are laminated alternating layers of isolated conductors and insulators

DOEpatents

Caporaso, George J.; Sampayan, Stephen E.; Kirbie, Hugh C.

1998-01-01

A dielectric-wall linear accelerator is improved by a high-voltage, fast rise-time switch that includes a pair of electrodes between which are laminated alternating layers of isolated conductors and insulators. A high voltage is placed between the electrodes sufficient to stress the voltage breakdown of the insulator on command. A light trigger, such as a laser, is focused along at least one line along the edge surface of the laminated alternating layers of isolated conductors and insulators extending between the electrodes. The laser is energized to initiate a surface breakdown by a fluence of photons, thus causing the electrical switch to close very promptly. Such insulators and lasers are incorporated in a dielectric wall linear accelerator with Blumlein modules, and phasing is controlled by adjusting the length of fiber optic cables that carry the laser light to the insulator surface.

Photoneutron radiation field of ducts in barrier of 15 MV medical electron accelerators

NASA Astrophysics Data System (ADS)

Deng, Lei; Zhou, Ning; Chen, Yi-shui; Tu, Yu

2017-11-01

Shielding body of the high-energy medical electron accelerators is always penetrated by ducts, which would influence the shielding capability of local barrier. In order to quantitatively analyze the duct's impact on shielding of the photoneutron from 15 MV accelerators, the ambient dose equivalent rate and energy spectrum at the center of a typical duct and the external mouth of duct were calculated based on MCNP program for the first time. The results demonstrate that leakage neutrons at the external mouth of duct are mainly thermal neutron, and its dose rate is decreased with the increase of the intersection angle between duct and wall as well as the reduction of duct diameter. When a duct in a diameter no more than 30 cm penetrates the wall unidirectionally and the inclined Angle (θ) is 60°, neutron dose rate at the external mouth of duct could meet the requirements of protection. At last, according to the calculation results, some suggestions are proposed for the shielding design of ducts in walls.

Calcium deprivation disrupts enlargement of Chara corallina cells: further evidence for the calcium pectate cycle.

PubMed

Proseus, Timothy E; Boyer, John S

2012-06-01

Pectin is a normal constituent of cell walls of green plants. When supplied externally to live cells or walls isolated from the large-celled green alga Chara corallina, pectin removes calcium from load-bearing cross-links in the wall, loosening the structure and allowing it to deform more rapidly under the action of turgor pressure. New Ca(2+) enters the vacated positions in the wall and the externally supplied pectin binds to the wall, depositing new wall material that strengthens the wall. A calcium pectate cycle has been proposed for these sub-reactions. In the present work, the cycle was tested in C. corallina by depriving the wall of external Ca(2+) while allowing the cycle to run. The prediction is that growth would eventually be disrupted by a lack of adequate deposition of new wall. The test involved adding pectate or the calcium chelator EGTA to the Ca(2+)-containing culture medium to bind the calcium while the cycle ran in live cells. After growth accelerated, turgor and growth eventually decreased, followed by an abrupt turgor loss and growth cessation. The same experiment with isolated walls suggested the walls of live cells became unable to support the plasma membrane. If instead the pectate or EGTA was replaced with fresh Ca(2+)-containing culture medium during the initial acceleration in live cells, growth was not disrupted and returned to the original rates. The operation of the cycle was thus confirmed, providing further evidence that growth rates and wall biosynthesis are controlled by these sub-reactions in plant cell walls.

Numerical Study of Single Bubble Growth on and Departure from a Horizontal Superheated Wall by Three-dimensional Lattice Boltzmann Method

NASA Astrophysics Data System (ADS)

Feng, Yuan; Li, Hui-Xiong; Guo, Kai-Kai; Zhao, Jian-Fu; Wang, Tai

2018-05-01

A three-dimensional hybrid lattice Boltzmann method was used to simulate the progress of a single bubble's growth and departure from a horizontal superheated wall. The evolutionary process of the bubble shapes and also the temperature fields during pool nucleate boiling were obtained and the influence of the gravitational acceleration on the bubble departure diameter (BDD), the bubble release frequency (BRF) and the heat flux on the superheated wall was analyzed. The simulation results obtained by the present three-dimensional numerical studies demonstrate that the BDD is proportional to g^{-0.301}, the BRF is proportional to g^{-0.58}, and the averaged wall heat flux is proportional to g^{0.201}, where g is the gravitational acceleration. These results are in good agreement with the common-used experimental correlations, indicating the rationality of the present numerical model and results.

Magnesium diboride coated bulk niobium: a new approach to higher acceleration gradient

NASA Astrophysics Data System (ADS)

Tan, Teng; Wolak, M. A.; Xi, X. X.; Tajima, T.; Civale, L.

2016-10-01

Bulk niobium Superconducting Radio-Frequency cavities are a leading accelerator technology. Their performance is limited by the cavity loss and maximum acceleration gradient, which are negatively affected by vortex penetration into the superconductor when the peak magnetic field at the cavity wall surface exceeds the vortex penetration field (Hvp). It has been proposed that coating the inner wall of an SRF cavity with superconducting thin films increases Hvp. In this work, we utilized Nb ellipsoid to simulate an inverse SRF cavity and investigate the effect of coating it with magnesium diboride layer on the vortex penetration field. A significant enhancement of Hvp was observed. At 2.8 K, Hvp increased from 2100 Oe for an uncoated Nb ellipsoid to 2700 Oe for a Nb ellipsoid coated with ~200 nm thick MgB2 thin film. This finding creates a new route towards achieving higher acceleration gradient in SRF cavity accelerator beyond the theoretical limit of bulk Nb.

Magnesium diboride coated bulk niobium: a new approach to higher acceleration gradient.

PubMed

Tan, Teng; Wolak, M A; Xi, X X; Tajima, T; Civale, L

2016-10-24

Bulk niobium Superconducting Radio-Frequency cavities are a leading accelerator technology. Their performance is limited by the cavity loss and maximum acceleration gradient, which are negatively affected by vortex penetration into the superconductor when the peak magnetic field at the cavity wall surface exceeds the vortex penetration field (H vp ). It has been proposed that coating the inner wall of an SRF cavity with superconducting thin films increases H vp . In this work, we utilized Nb ellipsoid to simulate an inverse SRF cavity and investigate the effect of coating it with magnesium diboride layer on the vortex penetration field. A significant enhancement of H vp was observed. At 2.8 K, H vp increased from 2100 Oe for an uncoated Nb ellipsoid to 2700 Oe for a Nb ellipsoid coated with ~200 nm thick MgB 2 thin film. This finding creates a new route towards achieving higher acceleration gradient in SRF cavity accelerator beyond the theoretical limit of bulk Nb.

Magnesium diboride coated bulk niobium: a new approach to higher acceleration gradient

NASA Astrophysics Data System (ADS)

Civale, Leonardo; Tan, Teng; Wolak, M.; Xi, Xiaoxing; Tajima, Tsuyoshi

Bulk niobium Superconducting Radio-Frequency cavities are a leading accelerator technology. Their performance is limited by the cavity loss and maximum acceleration gradient, which are negatively affected by vortex penetration into the superconductor when the peak magnetic field at the cavity wall surface exceeds the vortex penetration field (Hvp). It has been proposed that coating the inner wall of an SRF cavity with superconducting thin films increases Hvp. In this work, we utilized Nb ellipsoids to simulate an inverse SRF cavity and investigate the effect of coating it with magnesium diboride layer on the vortex penetration field. A significant enhancement of Hvp was observed. At 2.8 K, Hvp increased from 2100 Oe for an uncoated Nb ellipsoid to 2700 Oe for a Nb ellipsoid coated with 200 nm thick MgB2 thin film. This finding creates a new route towards achieving higher acceleration gradient in SRF cavity accelerator beyond the theoretical limit of bulk Nb.

Magnesium diboride coated bulk niobium: a new approach to higher acceleration gradient

PubMed Central

Tan, Teng; Wolak, M. A.; Xi, X. X.; Tajima, T.; Civale, L.

2016-01-01

Bulk niobium Superconducting Radio-Frequency cavities are a leading accelerator technology. Their performance is limited by the cavity loss and maximum acceleration gradient, which are negatively affected by vortex penetration into the superconductor when the peak magnetic field at the cavity wall surface exceeds the vortex penetration field (Hvp). It has been proposed that coating the inner wall of an SRF cavity with superconducting thin films increases Hvp. In this work, we utilized Nb ellipsoid to simulate an inverse SRF cavity and investigate the effect of coating it with magnesium diboride layer on the vortex penetration field. A significant enhancement of Hvp was observed. At 2.8 K, Hvp increased from 2100 Oe for an uncoated Nb ellipsoid to 2700 Oe for a Nb ellipsoid coated with ~200 nm thick MgB2 thin film. This finding creates a new route towards achieving higher acceleration gradient in SRF cavity accelerator beyond the theoretical limit of bulk Nb. PMID:27775087

Magnesium diboride coated bulk niobium: a new approach to higher acceleration gradient

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tan, Teng; Wolak, M. A.; Xi, X. X.

2016-10-24

Bulk niobium Superconducting Radio-Frequency cavities are a leading accelerator technology. Their performance is limited by the cavity loss and maximum acceleration gradient, which are negatively affected by vortex penetration into the superconductor when the peak magnetic field at the cavity wall surface exceeds the vortex penetration field (H vp). It has been proposed that coating the inner wall of an SRF cavity with superconducting thin films increases H vp. In this work, we utilized Nb ellipsoid to simulate an inverse SRF cavity and investigate the effect of coating it with magnesium diboride layer on the vortex penetration field. A significantmore » enhancement of H vp was observed. At 2.8 K, H vp increased from 2100 Oe for an uncoated Nb ellipsoid to 2700 Oe for a Nb ellipsoid coated with ~200 nm thick MgB 2 thin film. In conclusion, this finding creates a new route towards achieving higher acceleration gradient in SRF cavity accelerator beyond the theoretical limit of bulk Nb.« less

Synchrotron-based X-ray Fluorescence Microscopy in Conjunction with Nanoindentation to Study Molecular-Scale Interactions of Phenol–Formaldehyde in Wood Cell Walls

Treesearch

Joseph E. Jakes; Christopher G. Hunt; Daniel J. Yelle; Linda Lorenz; Kolby Hirth; Sophie-Charlotte Gleber; Stefan Vogt; Warren Grigsby; Charles R. Frihart

2015-01-01

Understanding and controlling molecular-scale interactions between adhesives and wood polymers are critical to accelerate the development of improved adhesives for advanced wood-based materials. The submicrometer resolution of synchrotron-based X-ray fluorescence microscopy (XFM) was found capable of mapping and quantifying infiltration of Br-labeled phenol−...

Beam trapping in high-current cyclic accelerators with strong-focusing fields. Memorandum report, January-December 1984

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sprangle, P.; Kapetanakos, C.A.

1985-03-06

In cyclic induction accelerators, the energy of the particles increases slowly in synchronism with the vertical (betatron) magnetic field. As a consequence of the slow acceleration, the charged particles must be confined by the weak-focusing magnetic field over long periods of time, and thus field errors, instabilities, and radiation losses can impose limitations on the acceleration process. These limitations can be substantially relaxed if the acceleration were to occur rapidly, say over a few microseconds. An appropriate name for such an accelerator is REBA-TRON (Rapid Electron Beam Accelerator). This paper considers a possible mechanism which could trap a high currentmore » electron beam in the strong focusing magnetic fields of the rebatron. We investigate a possible mechanism for trapping an intense relativistic electron beam confined by strong focusing fields. In our model the electron beam is assumed to be injected into torsatron fields off axis, near the chamber walls. The finite resistivity of the walls results in a drag force on the beam centroid which may cause the beam to spiral inward towards the axis of the chamber. We have analyzed this mechanism and obtained decay rates for the inward spiraling beam motion.« less

Enabling More than Moore: Accelerated Reliability Testing and Risk Analysis for Advanced Electronics Packaging

NASA Technical Reports Server (NTRS)

Ghaffarian, Reza; Evans, John W.

2014-01-01

For five decades, the semiconductor industry has distinguished itself by the rapid pace of improvement in miniaturization of electronics products-Moore's Law. Now, scaling hits a brick wall, a paradigm shift. The industry roadmaps recognized the scaling limitation and project that packaging technologies will meet further miniaturization needs or ak.a "More than Moore". This paper presents packaging technology trends and accelerated reliability testing methods currently being practiced. Then, it presents industry status on key advanced electronic packages, factors affecting accelerated solder joint reliability of area array packages, and IPC/JEDEC/Mil specifications for characterizations of assemblies under accelerated thermal and mechanical loading. Finally, it presents an examples demonstrating how Accelerated Testing and Analysis have been effectively employed in the development of complex spacecraft thereby reducing risk. Quantitative assessments necessarily involve the mathematics of probability and statistics. In addition, accelerated tests need to be designed which consider the desired risk posture and schedule for particular project. Such assessments relieve risks without imposing additional costs. and constraints that are not value added for a particular mission. Furthermore, in the course of development of complex systems, variances and defects will inevitably present themselves and require a decision concerning their disposition, necessitating quantitative assessments. In summary, this paper presents a comprehensive view point, from technology to systems, including the benefits and impact of accelerated testing in offsetting risk.

Low cost friction seismic base-isolation of residential new masonry buildings in developing countries: A small masonry house case study

NASA Astrophysics Data System (ADS)

Habieb, A. B.; Milani, G.; Tavio, T.; Milani, F.

2017-07-01

A Finite element model was established to examine performance of a low-cost friction base-isolation system in reducing seismic vulnerability of rural buildings. This study adopts an experimental investigation of the isolation system which was conducted in India. Four friction isolation interfaces, namely, marble-marble, marble-high-density polyethylene, marble-rubber sheet, and marble-geosynthetic were involved. Those interfaces differ in static and dynamic friction coefficient obtained through previous research. The FE model was performed based on a macroscopic approach and the masonry wall is assumed as an isotropic element. In order to observe structural response of the masonry house, elastic and plastic parameters of the brick wall were studied. Concrete damage plasticity (CDP) model was adopted to determine non-linear behavior of the brick wall. The results of FE model shows that involving these friction isolation systems could much decrease response acceleration at roof level. It was found that systems with marble-marble and marble-geosynthetic interfaces reduce the roof acceleration up to 50% comparing to the system without isolation. Another interesting result is there was no damage appearing in systems with friction isolation during the test. Meanwhile a severe failure was clearly visible for a system without isolation.

Experimental Investigation of the Near-Wall Region in the NASA HiVHAc EDU2 Hall Thruster

NASA Technical Reports Server (NTRS)

Shastry, Rohit; Kamhawi, Hani; Huang, Wensheng; Haag, Thomas W.

2015-01-01

The HiVHAc propulsion system is currently being developed to support Discovery-class NASA science missions. Presently, the thruster meets the required operational lifetime by utilizing a novel discharge channel replacement mechanism. As a risk reduction activity, an alternative approach is being investigated that modifies the existing magnetic circuit to shift the ion acceleration zone further downstream such that the magnetic components are not exposed to direct ion impingement during the thruster's lifetime while maintaining adequate thruster performance and stability. To measure the change in plasma properties between the original magnetic circuit configuration and the modified, "advanced" configuration, six Langmuir probes were flush-mounted within each channel wall near the thruster exit plane. Plasma potential and electron temperature were measured for both configurations across a wide range of discharge voltages and powers. Measurements indicate that the upstream edge of the acceleration zone shifted downstream by as much as 0.104 channel lengths, depending on operating condition. The upstream edge of the acceleration zone also appears to be more insensitive to operating condition in the advanced configuration, remaining between 0.136 and 0.178 channel lengths upstream of the thruster exit plane. Facility effects studies performed on the original configuration indicate that the plasma and acceleration zone recede further upstream into the channel with increasing facility pressure. These results will be used to inform further modifications to the magnetic circuit that will provide maximum protection of the magnetic components without significant changes to thruster performance and stability.

Secondary Electron Emission from Plasma Processed Accelerating Cavity Grade Niobium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Basovic, Milos

Advances in the particle accelerator technology have enabled numerous fundamental discoveries in 20th century physics. Extensive interdisciplinary research has always supported further development of accelerator technology in efforts of reaching each new energy frontier. Accelerating cavities, which are used to transfer energy to accelerated charged particles, have been one of the main focuses of research and development in the particle accelerator field. Over the last fifty years, in the race to break energy barriers, there has been constant improvement of the maximum stable accelerating field achieved in accelerating cavities. Every increase in the maximum attainable accelerating fields allowed for highermore » energy upgrades of existing accelerators and more compact designs of new accelerators. Each new and improved technology was faced with ever emerging limiting factors. With the standard high accelerating gradients of more than 25 MV/m, free electrons inside the cavities get accelerated by the field, gaining enough energy to produce more electrons in their interactions with the walls of the cavity. The electron production is exponential and the electron energy transfer to the walls of a cavity can trigger detrimental processes, limiting the performance of the cavity. The root cause of the free electron number gain is a phenomenon called Secondary Electron Emission (SEE). Even though the phenomenon has been known and studied over a century, there are still no effective means of controlling it. The ratio between the electrons emitted from the surface and the impacting electrons is defined as the Secondary Electron Yield (SEY). A SEY ratio larger than 1 designates an increase in the total number of electrons. In the design of accelerator cavities, the goal is to reduce the SEY to be as low as possible using any form of surface manipulation. In this dissertation, an experimental setup was developed and used to study the SEY of various sample surfaces that were treated by different techniques. Specifically, this work provides the results of SEY from the plasma cleaned cavity grade niobium (Nb) samples. Pure niobium is currently the material of choice for the fabrication of Superconducting Radio Frequency (SRF) cavities. The effect of plasma processing with two different gases will be examined in two groups of samples. The first group of samples is made from cavity grade niobium. The second group of samples is made from the same material, but include a welded joint made by electron beam welding, since in niobium SRF cavities the peak electric and magnetic field are seen in close proximity to the welded joints. Both groups of samples will be exposed to nitrogen (N2) and a mixture of argon with oxygen (Ar/O2) plasma. It is the goal of this research to determine the SEY on these two groups of samples before and after plasma processing as a function of the energy of primary electrons. The SEY as a function of the angle of incidence of the primary electrons is tested on the samples treated with Ar/O2 plasma.« less

Elimination of Gravity Influence on Flame Propagation Via Enhancement of the Saffman-Taylor Instability

NASA Technical Reports Server (NTRS)

Aldredge, R. C.

2003-01-01

In this analytical work the influence of the Saffman-Taylor instability on flame propagation is formulated for computational investigation. Specifically, it is of interest to examine the influence of this instability as a potential means of eliminating the effect of gravitational acceleration on the development of thermoacoustic instability. Earlier experimental investigations of thermoacoustic instability employed tubes of large circular or annular cross-section, such that neither heat loss nor viscosity at the burner walls was of significant importance in influencing flame behavior. However, it has been demonstrated recently that flames propagating between closely spaced walls, may be subject to long-wavelength wrinkling associated with the Saffman-Taylor instability, known to be relevant when a less-viscous fluid pushes a more-viscous fluid through a porous medium or between two closely spaced walls.

Synchrotron-based X-ray Fluorescence Microscopy in Conjunction with Nanoindentation to Study Molecular-Scale Interactions of Phenol-Formaldehyde in Wood Cell Walls

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jakes, Joseph E.; Hunt, Chris G.; Yelle, Daniel J.

Understanding and controlling molecular-scale interactions between adhesives and wood polymers are critical to accelerate the development of improved adhesives for advanced wood-based materials. The submicrometer resolution of synchrotron-based X-ray fluorescence microscopy (XFM) was found capable of mapping and quantifying infiltration of Br-labeled phenolformaldehyde (BrPF) into wood cell walls. Cell wall infiltration of five BrPF adhesives with different average molecular weights (MWs) was mapped. Nanoindentation on the same cell walls was performed to assess the effects of BrPF infiltration on cell wall hygromechanical properties. For the same amount of weight uptake, lower MW BrPF adhesives were found to be more effectivemore » at decreasing moisture-induced mechanical softening. This greater effectiveness of lower MW phenolic adhesives likely resulted from their ability to more intimately associate with water sorption sites in the wood polymers. Evidence also suggests that a BrPF interpenetrating polymer network (IPN) formed within the wood polymers, which might also decrease moisture sorption by mechanically restraining wood polymers during swelling.« less

Effects of reactive oxygen species on cellular wall disassembly of banana fruit during ripening.

PubMed

Cheng, Guiping; Duan, Xuewu; Shi, John; Lu, Wangjin; Luo, Yunbo; Jiang, Weibo; Jiang, Yueming

2008-07-15

Fruit softening is generally attributed to cell wall disassembly. Experiments were conducted to investigate effects of various reactive oxygen species (ROS) on in vitro cellular wall disassembly of harvested banana fruit. The alcohol-extracted insoluble residue (AEIR) was obtained from the pulp tissues of banana fruit at various ripening stages and then used to examine the disassembly of cellular wall polysaccharides in the presence of superoxide anion (O2(-)), hydrogen peroxide (H2O2) or hydroxyl radical (OH) and their scavengers. The presence of OH accelerated significantly disassembly of cellular wall polysaccharides in terms of the increase in contents of total sugars released and uronic acid, and the decrease in molecular mass of soluble polysaccharides, using gel permeation chromatography. However, the treatment with H2O2 or O2(-) showed no significant effect on the disassembly of cellular wall polysaccharides. Furthermore, the degradation of the de-esterified AEIR was more susceptible to OH attack than the esterified AEIR. In addition, the effect of OH could be inhibited in the presence of OH scavenger. This study suggests that disassembly of cellular wall polysaccharides could be initiated by OH as the solublisation of the polysaccharides increased, which, in turn, accelerated fruit softening. Copyright © 2008 Elsevier Ltd. All rights reserved.

FLOW SEPARATION CONDITIONS AT PIPE WALLS OF WATER DISTRIBUTION MAINS

EPA Science Inventory

Biofilm formations on pipe walls have been found in potable water distribution mains. The biofilm layers contribute to accelerated corrosion rates, increased flow resistance, and formation of encrustations that may deteriorate drinking water quality. Research to evaluate the depe...

Intermittency of acceleration in isotropic turbulence.

PubMed

Lee, Sang; Lee, Changhoon

2005-05-01

The intermittency of acceleration is investigated for isotropic turbulence using direct numerical simulation. Intermittently found acceleration of large magnitude always points towards the rotational axis of a vortex filament, indicating that the intermittency of acceleration is associated with the rotational motion of the vortices that causes centripetal acceleration, which is consistent with the reported result for the near-wall turbulence. Furthermore, investigation on movements of such vortex filaments provides some insights into the dynamics of local dissipation, enstrophy and acceleration. Strong dissipation partially covering the edge of a vortex filament shows weak correlation with enstrophy, while it is strongly correlated with acceleration.

Neutral beam monitoring

DOEpatents

Fink, Joel H.

1981-08-18

Method and apparatus for monitoring characteristics of a high energy neutral beam. A neutral beam is generated by passing accelerated ions through a walled cell containing a low energy neutral gas, such that charge exchange neutralizes the high energy ion beam. The neutral beam is monitored by detecting the current flowing through the cell wall produced by low energy ions which drift to the wall after the charge exchange. By segmenting the wall into radial and longitudinal segments various beam conditions are further identified.

Cost optimization of reinforced concrete cantilever retaining walls under seismic loading using a biogeography-based optimization algorithm with Levy flights

NASA Astrophysics Data System (ADS)

Aydogdu, Ibrahim

2017-03-01

In this article, a new version of a biogeography-based optimization algorithm with Levy flight distribution (LFBBO) is introduced and used for the optimum design of reinforced concrete cantilever retaining walls under seismic loading. The cost of the wall is taken as an objective function, which is minimized under the constraints implemented by the American Concrete Institute (ACI 318-05) design code and geometric limitations. The influence of peak ground acceleration (PGA) on optimal cost is also investigated. The solution of the problem is attained by the LFBBO algorithm, which is developed by adding Levy flight distribution to the mutation part of the biogeography-based optimization (BBO) algorithm. Five design examples, of which two are used in literature studies, are optimized in the study. The results are compared to test the performance of the LFBBO and BBO algorithms, to determine the influence of the seismic load and PGA on the optimal cost of the wall.

Three-dimensional black-blood multi-contrast carotid imaging using compressed sensing: a repeatability study.

PubMed

Yuan, Jianmin; Usman, Ammara; Reid, Scott A; King, Kevin F; Patterson, Andrew J; Gillard, Jonathan H; Graves, Martin J

2018-02-01

The purpose of this work is to evaluate the repeatability of a compressed sensing (CS) accelerated multi-contrast carotid protocol at 3 T. Twelve volunteers and eight patients with carotid disease were scanned on a 3 T MRI scanner using a CS accelerated 3-D black-blood multi-contrast protocol which comprises T 1 w, T 2 w and PDw without CS, and with a CS factor of 1.5 and 2.0. The volunteers were scanned twice, the lumen/wall area and wall thickness were measured for each scan. Eight patients were scanned once, the inter/intra-observer reproducibility of the measurements was calculated. In the repeated volunteer scans, the interclass correlation coefficient (ICC) for the wall area measurement using a CS factor of 1.5 in PDw, T 1 w and T 2 w were 0.95, 0.81, and 0.97, respectively. The ICC for lumen area measurement using a CS factor of 1.5 in PDw, T 1 w and T 2 w were 0.96, 0.92, and 0.96, respectively. In patients, the ICC for inter/intra-observer measurements of lumen/wall area, and wall thickness were all above 0.81 in all sequences. The results show a CS accelerated 3-D black-blood multi-contrast protocol is a robust and reproducible method for carotid imaging. Future protocol design could use CS to reduce the scanning time.

Environmental continuous air monitor inlet with combined preseparator and virtual impactor

DOEpatents

Rodgers, John C [Santa Fe, NM

2007-06-19

An inlet for an environmental air monitor is described wherein a pre-separator interfaces with ambient environment air and removes debris and insects commonly associated with high wind outdoors and a deflector plate in communication with incoming air from the pre-separator stage, that directs the air radially and downward uniformly into a plurality of accelerator jets located in a manifold of a virtual impactor, the manifold being cylindrical and having a top, a base, and a wall, with the plurality of accelerator jets being located in the top of the manifold and receiving the directed air and accelerating directed air, thereby creating jets of air penetrating into the manifold, where a major flow is deflected to the walls of the manifold and extracted through ports in the walls. A plurality of receiver nozzles are located in the base of the manifold coaxial with the accelerator jets, and a plurality of matching flow restrictor elements are located in the plurality of receiver nozzles for balancing and equalizing the total minor flow among all the plurality of receiver nozzles, through which a lower, fractional flow extracts large particle constituents of the air for collection on a sample filter after passing through the plurality of receiver nozzles and the plurality of matching flow restrictor elements.

The limiting velocity effect in a magnetically held discharge with a moving wall

NASA Astrophysics Data System (ADS)

Drobyshevskii, E. M.; Zhukov, B. G.; Nazarov, E. V.; Rozov, S. I.; Sokolov, V. M.; Kurakin, R. O.

1991-08-01

Experiments are reported in which bodies with a mass of about 1 g were accelerated in nearly constant current regimes by using a discharge magnetically held against the channel wall, with maximum permissible accelerations of 3.5 x 10 exp 6 g and linear current densities of 60 kA/mm. A saturation of the velocity was observed at 4-6 mm/microsec. The velocity limit does not depend on the current intensity and duration or linear electrode inductance and is proportional to m exp -1/2; it is practically unaffected by the characteristics of body friction against the channel walls and by small deviations of the current pulse shape from its constant value. A simple empirical theory is proposed which provides an adequate description of the experimentally observed phenomena.

Classical and quantum localization and delocalization in the Fermi accelerator, kicked rotor and two-sided kicked rotor models

NASA Astrophysics Data System (ADS)

Zaslavsky, M.

1996-06-01

The phenomena of dynamical localization, both classical and quantum, are studied in the Fermi accelerator model. The model consists of two vertical oscillating walls and a ball bouncing between them. The classical localization boundary is calculated in the case of ``sinusoidal velocity transfer'' [A. J. Lichtenberg and M. A. Lieberman, Regular and Stochastic Motion (Springer-Verlag, Berlin, 1983)] on the basis of the analysis of resonances. In the case of the ``sawtooth'' wall velocity we show that the quantum localization is determined by the analytical properties of the canonical transformations to the action and angle coordinates of the unperturbed Hamiltonian, while the existence of the classical localization is determined by the number of continuous derivatives of the distance between the walls with respect to time.

Study of low vibration 4 K pulse tube cryocoolers

NASA Astrophysics Data System (ADS)

Xu, Mingyao; Nakano, Kyosuke; Saito, Motokazu; Takayama, Hirokazu; Tsuchiya, Akihiro; Maruyama, Hiroki

2012-06-01

Sumitomo Heavy Industries, Ltd. (SHI) has been continuously improving the efficiency and reducing the vibration of a 4 K pulse tube cryocooler. One advantage of a pulse tube cryocooler over a GM cryocooler is low vibration. In order to reduce vibration, both the displacement and the acceleration have to be reduced. The vibration acceleration can be reduced by splitting the valve unit from the cold head. One simple way to reduce vibration displacement is to increase the wall thickness of the tubes on the cylinder. However, heat conduction loss increases while the wall thickness increases. To overcome this dilemma, a novel concept, a tube with non-uniform wall thickness, is proposed. Theoretical analysis of this concept, and the measured vibration results of an SHI lowvibration pulse tube cryocooler, will be introduced in this paper.

Strength of unbonded post-tensioned walls.

DOT National Transportation Integrated Search

2014-08-01

Post-tensioned masonry wall (PT-MW) is an ideal candidate for accelerating the construction of sound barriers in highways. PT-MWs : have been in use for a while in buildings; however, there has been no rigorous single-study in the U. S. about in-plan...

Shelf-Stable Adhesive for Reduction of Composite Repair Hazardous Waste

DTIC Science & Technology

2008-09-01

1. Our microencapsulation approach is compatible with commonly used epoxy resins and catalyst accelerants 2. The microcapsules can be...thermally stable barrier to diffusion of accelerant and/or epoxy resin through the capsule’s walls [14]. 3.2 Microencapsulation Microcapsules ... microencapsulation of the catalyst accelerant. Thermal analysis of microcapsules made from carrageenan blends showed that they formed an effective

Dynamic Finite Element Predictions for Mars Sample Return Cellular Impact Test #4

NASA Technical Reports Server (NTRS)

Fasanella, Edwin L.; Billings, Marcus D.

2001-01-01

The nonlinear, transient dynamic finite element code, MSC.Dytran, was used to simulate an impact test of an energy absorbing Earth Entry Vehicle (EEV) that will impact without a parachute. EEVOs are designed to return materials from asteroids, comets, or planets for laboratory analysis on Earth. The EEV concept uses an energy absorbing cellular structure designed to contain and limit the acceleration of space exploration samples during Earth impact. The spherical shaped cellular structure is composed of solid hexagonal and pentagonal foam-filled cells with hybrid graphite-epoxy/Kevlar cell walls. Space samples fit inside a smaller sphere at the center of the EEVOs cellular structure. Pre-test analytical predictions were compared with the test results from a bungee accelerator. The model used to represent the foam and the proper failure criteria for the cell walls were critical in predicting the impact loads of the cellular structure. It was determined that a FOAM1 model for the foam and a 20% failure strain criteria for the cell walls gave an accurate prediction of the acceleration pulse for cellular impact.

Effect of Gravity on the Mammalian Cell Deformation

NASA Technical Reports Server (NTRS)

Hung, R. J.; Tsao, Y.; Gonda, Steven

1995-01-01

The effect of human cell immersed in culture liquid under a micro-gravity environment has been investigated. The study is based on the numerical simulation of the configuration of human cell affected by the time dependent variation of gravity acceleration ranging from 10(exp -3) to 2 g(sub o) (g(sub o) = 9.81 m/s(exp 2)) in 15 seconds. Both the free floating cell and the cell contacted to the upper and lower inclined walls imposed by the time-dependent reduced gravity acceleration are considered in this study. The results show that the cell configuration changes from spherical to horizontally elongated ellipsoid for both the free floating cell and the cell sitting on the lower inclined wall while the cell configuration varies from spherical to vertically elongated ellipsoid for the cell hanging to the upper inclined wall when the gravity acceleration increases. Experimental observations, carried out of human cells exposed to the variation of gravity levels, show that the results of experimental observations agree exactly with the theoretical model computation described in this paper. These results sre significant for humans exposed to the micro-gravity environment.

Air film cooling in a nonadiabatic wall conical nozzle.

NASA Technical Reports Server (NTRS)

Boldman, D. R.; Papell, S. S.; Ehlers, R. C.

1972-01-01

Experimental data for an air-film cooled conical nozzle operating with a heated-air main stream and a water-cooled wall confirm the validity of Lieu's (1964) method for correlating film cooling data in the accelerated flow of a nonadiabatic-wall nozzle. The film cooling effectiveness modified for nonadiabatic walls by Lieu can be used to correlate film cooling under the condition that the main-stream to coolant velocity ratio at the slot is about 1. Such a ratio provides the optimum cooling effectiveness.

Diagnostic resonant cavity for a charged particle accelerator

DOEpatents

Barov, Nikolai

2007-10-02

Disclosed is a diagnostic resonant cavity for determining characteristics of a charged particle beam, such as an electron beam, produced in a charged particle accelerator. The cavity is based on resonant quadrupole-mode and higher order cavities. Enhanced shunt impedance in such cavities is obtained by the incorporation of a set of four or more electrically conductive rods extending inwardly from either one or both of the end walls of the cavity, so as to form capacitive gaps near the outer radius of the beam tube. For typical diagnostic cavity applications, a five-fold increase in shunt impedance can be obtained. In alternative embodiments the cavity may include either four or more opposing pairs of rods which extend coaxially toward one another from the opposite end walls of the cavity and are spaced from one another to form capacitative gaps; or the cavity may include a single set of individual rods that extend from one end wall to a point adjacent the opposing end wall.

High spatial resolution measurements of ram accelerator gas dynamic phenomena

NASA Technical Reports Server (NTRS)

Hinkey, J. B.; Burnham, E. A.; Bruckner, A. P.

1992-01-01

High spatial resolution experimental tube wall pressure measurements of ram accelerator gas dynamic phenomena are presented. The projectile resembles the centerbody of a ramjet and travels supersonically through a tube filled with a combustible gaseous mixture, with the tube acting as the outer cowling. Pressure data are recorded as the projectile passes by sensors mounted in the tube wall at various locations along the tube. Data obtained by using a special highly instrumented section of tube has allowed the recording of gas dynamic phenomena with a spatial resolution on the order of one tenth the projectile length. High spatial resolution tube wall pressure data from the three regimes of propulsion studied to date (subdetonative, transdetonative, and superdetonative) are presented and reveal the 3D character of the flowfield induced by projectile fins and the canting of the projectile body relative to the tube wall. Also presented for comparison to the experimental data are calculations made with an inviscid, 3D CFD code.

Optically pulsed electron accelerator

DOEpatents

Fraser, John S.; Sheffield, Richard L.

1987-01-01

An optically pulsed electron accelerator can be used as an injector for a free electron laser and comprises a pulsed light source, such as a laser, for providing discrete incident light pulses. A photoemissive electron source emits electron bursts having the same duration as the incident light pulses when impinged upon by same. The photoemissive electron source is located on an inside wall of a radio frequency powered accelerator cell which accelerates the electron burst emitted by the photoemissive electron source.

Optically pulsed electron accelerator

DOEpatents

Fraser, J.S.; Sheffield, R.L.

1985-05-20

An optically pulsed electron accelerator can be used as an injector for a free electron laser and comprises a pulsed light source, such as a laser, for providing discrete incident light pulses. A photoemissive electron source emits electron bursts having the same duration as the incident light pulses when impinged upon by same. The photoemissive electron source is located on an inside wall of a radiofrequency-powered accelerator cell which accelerates the electron burst emitted by the photoemissive electron source.

Combined Mini-Cylex & Disk Acceleration Tests in Type K Copper.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maines, Warren Russell; Kittell, David E.; Hobbs, Michael L.

We combined the miniature cylinder expansion test (Mini-Cylex), with the Disk Acceleration Test (DAX) using Type K copper, Picatinny Liquid Explosive, and photonic Doppler velocimetry. We estimated the CJ state using plate reverberation methods at the test cap. We extracted velocities at 2, 7, and 10 volume expansions to fit Jones-Wilkins-Lee Equation of State at the tube wall. And we estimated Gurney velocity both at the test cap and tube wall. Our experiments and simulations are within expected uncertainty. The test and the analysis effectively reduce costs while keeping similar fidelity compared with more expensive tests.

Nonlinear analysis of aortic flow in living dogs.

NASA Technical Reports Server (NTRS)

Ling, S. C.; Atabek, H. B.; Letzing, W. G.; Patel, D. J.

1973-01-01

A nonlinear theory which considered the convective accelerations of blood and the nonlinear elastic behavior and taper angle of the vascular wall was used to study the nature of blood flow in the descending thoracic aorta of living dogs under a wide range of pressures and flows. Velocity profiles, wall friction, and discharge waves were predicted from locally measured input data about the pressure-gradient wave and arterial distention. The results indicated that a major part of the mean pressure gradient was balanced by convective accelerations; the theory, which took this factor into account, predicted the correct velocity distributions and flow waves.

Wall shear stress measurements using a new transducer

NASA Technical Reports Server (NTRS)

Vakili, A. D.; Wu, J. M.; Lawing, P. L.

1986-01-01

A new instrument has been developed for direct measurement of wall shear stress. This instrument is simple and symmetric in design with small moving mass and no internal friction. Features employed in the design of this instrument eliminate most of the difficulties associated with the traditional floating element balances. Vibration problems associated with the floating element skin friction balances have been found to be minimized by the design features and optional damping provided. The unique design of this instrument eliminates or reduces the errors associated with conventional floating-element devices: such as errors due to gaps, pressure gradient, acceleration, heat transfer and temperature change. The instrument is equipped with various sensing systems and the output signal is a linear function of the wall shear stress. Measurement made in three different tunnels show good agreement with theory and data obtained by the floating element devices.

Seismic analysis for translational failure of landfills with retaining walls.

PubMed

Feng, Shi-Jin; Gao, Li-Ya

2010-11-01

In the seismic impact zone, seismic force can be a major triggering mechanism for translational failures of landfills. The scope of this paper is to develop a three-part wedge method for seismic analysis of translational failures of landfills with retaining walls. The approximate solution of the factor of safety can be calculated. Unlike previous conventional limit equilibrium methods, the new method is capable of revealing the effects of both the solid waste shear strength and the retaining wall on the translational failures of landfills during earthquake. Parameter studies of the developed method show that the factor of safety decreases with the increase of the seismic coefficient, while it increases quickly with the increase of the minimum friction angle beneath waste mass for various horizontal seismic coefficients. Increasing the minimum friction angle beneath the waste mass appears to be more effective than any other parameters for increasing the factor of safety under the considered condition. Thus, selecting liner materials with higher friction angle will considerably reduce the potential for translational failures of landfills during earthquake. The factor of safety gradually increases with the increase of the height of retaining wall for various horizontal seismic coefficients. A higher retaining wall is beneficial to the seismic stability of the landfill. Simply ignoring the retaining wall will lead to serious underestimation of the factor of safety. Besides, the approximate solution of the yield acceleration coefficient of the landfill is also presented based on the calculated method. Copyright © 2010 Elsevier Ltd. All rights reserved.

Computation of laminar heat transfer from gaseous plasmas in electromagnetic fields

NASA Technical Reports Server (NTRS)

Bose, T. K.

1972-01-01

Heat transfer analysis procedure is presented for two-temperature gaseous plasma. Analysis is based on laminar flow of singly-ionized, quasineutral plasma with variable properties. Sheath analysis is described for species in accelerating field, decelerating field, emitted from wall, and recombining at wall.

Conducting wall Hall thrusters in magnetic shielding and standard configurations

NASA Astrophysics Data System (ADS)

Grimaud, Lou; Mazouffre, Stéphane

2017-07-01

Traditional Hall thrusters are fitted with boron nitride dielectric discharge channels that confine the plasma discharge. Wall properties have significant effects on the performances and stability of the thrusters. In magnetically shielded thrusters, interactions between the plasma and the walls are greatly reduced, and the potential drop responsible for ion acceleration is situated outside the channel. This opens the way to the utilization of alternative materials for the discharge channel. In this work, graphite walls are compared to BN-SiO2 walls in the 200 W magnetically shielded ISCT200-MS and the unshielded ISCT200-US Hall thrusters. The magnetically shielded thruster shows no significant change in the discharge current mean value and oscillations, while the unshielded thruster's discharge current increases by 25% and becomes noticeably less stable. The electric field profile is also investigated through laser spectroscopy, and no significant difference is recorded between the ceramic and graphite cases for the shielded thruster. The unshielded thruster, on the other hand, has its acceleration region shifted 15% of the channel length downstream. Lastly, the plume profile is measured with planar probes fitted with guard rings. Once again the material wall has little influence on the plume characteristics in the shielded thruster, while the unshielded one is significantly affected.

Unloading Characteristics of Sand-drift in Wind-shallow Areas along Railway and the Effect of Sand Removal by Force of Wind

PubMed Central

Cheng, Jian-jun; Xin, Guo-Wei; Zhi, Ling-yan; Jiang, Fu-qiang

2017-01-01

Wind-shield walls decrease the velocity of wind-drift sand flow in transit. This results in sand accumulating in the wind-shadow zone of both windshield wall and track line, causing severe sand sediment hazard. This study reveals the characteristics of sand accumulation and the laws of wind-blown sand removal in the wind-shadow areas of three different types of windshield walls, utilizing three-dimensional numerical simulations and wind tunnel experiments and on-site sand sediment tests. The results revealed the formation of apparent vortex and acceleration zones on the leeward side of solid windshield walls. For uniform openings, the vortex area moved back and narrowed. When bottom-opening windshield walls were adopted, the track-supporting layer at the step became a conflux acceleration zone, forming a low velocity vortex zone near the track line. At high wind speeds, windshield walls with bottom-openings achieved improved sand dredging. Considering hydrodynamic mechanisms, the flow field structure on the leeward side of different types of windshield structures is a result of convergence and diffusion of fluids caused by an obstacle. This convergence and diffusion effect of air fluid is more apparent at high wind velocities, but not obvious at low wind velocities. PMID:28120915

Dynamic Finite Element Predictions for Mars Sample Return Cellular Impact Test #4

NASA Technical Reports Server (NTRS)

Fasanella, Edwin L.; Billings, Marcus D.

2001-01-01

The nonlinear finite element program MSC.Dytran was used to predict the impact pulse for (he drop test of an energy absorbing cellular structure. This pre-test simulation was performed to aid in the design of an energy absorbing concept for a highly reliable passive Earth Entry Vehicle (EEV) that will directly impact the Earth without a parachute. In addition, a goal of the simulation was to bound the acceleration pulse produced and delivered to the simulated space cargo container. EEV's are designed to return materials from asteroids, comets, or planets for laboratory analysis on Earth. The EEV concept uses an energy absorbing cellular structure designed to contain and limit the acceleration of space exploration samples during Earth impact. The spherical shaped cellular structure is composed of solid hexagonal and pentagonal foam-filled cells with hybrid graphite-epoxy/Kevlar cell walls. Space samples fit inside a smaller sphere at the enter of the EEV's cellular structure. The material models and failure criteria were varied to determine their effect on the resulting acceleration pulse. Pre-test analytical predictions using MSC.Dytran were compared with the test results obtained from impact test #4 using bungee accelerator located at the NASA Langley Research Center Impact Dynamics Research Facility. The material model used to represent the foam and the proper failure criteria for the cell walls were critical in predicting the impact loads of the cellular structure. It was determined that a FOAMI model for the foam and a 20% failure strain criteria for the cell walls gave an accurate prediction of the acceleration pulse for drop test #4.

Exposure to chronic alcohol accelerates development of wall stress and eccentric remodeling in rats with volume overload.

PubMed

Mouton, Alan J; Ninh, Van K; El Hajj, Elia C; El Hajj, Milad C; Gilpin, Nicholas W; Gardner, Jason D

2016-08-01

Chronic alcohol abuse is one of the leading causes of dilated cardiomyopathy (DCM) in the United States. Volume overload (VO) also produces DCM characterized by left ventricular (LV) dilatation and reduced systolic and diastolic function, eventually progressing to congestive heart failure. For this study, we hypothesized that chronic alcohol exposure would exacerbate cardiac dysfunction and remodeling due to VO. Aortocaval fistula surgery was used to induce VO, and compensatory cardiac remodeling was allowed to progress for either 3days (acute) or 8weeks (chronic). Alcohol was administered via chronic intermittent ethanol vapor (EtOH) for 2weeks before the acute study and for the duration of the 8week chronic study. Temporal alterations in LV function were assessed by echocardiography. At the 8week end point, pressure-volume loop analysis was performed by LV catheterization and cardiac tissue collected. EtOH did not exacerbate LV dilatation (end-systolic and diastolic diameter) or systolic dysfunction (fractional shortening, ejection fraction) due to VO. The combined stress of EtOH and VO decreased the eccentric index (posterior wall thickness to end-diastolic diameter ratio), increased end-diastolic pressure (EDP), and elevated diastolic wall stress. VO also led to increases in posterior wall thickness, which was not observed in the VO+EtOH group, and wall thickness significantly correlated with LV BNP expression. VO alone led to increases in interstitial collagen staining (picrosirius red), which while not statistically significant, tended to be decreased by EtOH. VO increased LV collagen I protein expression, whereas in rats with VO+EtOH, LV collagen I was not elevated relative to Sham. The combination of VO and EtOH also led to increases in LV collagen III expression relative to Sham. Rats with VO+EtOH had significantly lower collagen I/III ratio than rats with VO alone. During the acute remodeling phase of VO (3days), VO significantly increased collagen III expression, whereas this effect was not observed in rats with VO+EtOH. In conclusion, chronic EtOH accelerates the development of elevated wall stress and promotes early eccentric remodeling in rats with VO. Our data indicate that these effects may be due to disruptions in compensatory hypertrophy and extracellular matrix remodeling in response to volume overload. Copyright © 2016 Elsevier Ltd. All rights reserved.

Development and application of an information-analytic system on the problem of flow accelerated corrosion of pipeline elements in the secondary coolant circuit of VVER-440-based power units at the Novovoronezh nuclear power plant

NASA Astrophysics Data System (ADS)

Tomarov, G. V.; Povarov, V. P.; Shipkov, A. A.; Gromov, A. F.; Kiselev, A. N.; Shepelev, S. V.; Galanin, A. V.

2015-02-01

Specific features relating to development of the information-analytical system on the problem of flow-accelerated corrosion of pipeline elements in the secondary coolant circuit of the VVER-440-based power units at the Novovoronezh nuclear power plant are considered. The results from a statistical analysis of data on the quantity, location, and operating conditions of the elements and preinserted segments of pipelines used in the condensate-feedwater and wet steam paths are presented. The principles of preparing and using the information-analytical system for determining the lifetime to reaching inadmissible wall thinning in elements of pipelines used in the secondary coolant circuit of the VVER-440-based power units at the Novovoronezh NPP are considered.

Ultrasonic Measurement of Erosion/corrosion Rates in Industrial Piping Systems

NASA Astrophysics Data System (ADS)

Sinclair, A. N.; Safavi, V.; Honarvar, F.

2011-06-01

Industrial piping systems that carry aggressive corrosion or erosion agents may suffer from a gradual wall thickness reduction that eventually threatens pipe integrity. Thinning rates could be estimated from the very small change in wall thickness values measured by conventional ultrasound over a time span of at least a few months. However, measurements performed over shorter time spans would yield no useful information—minor signal distortions originating from grain noise and ultrasonic equipment imperfections prevent a meaningful estimate of the minuscule reduction in echo travel time. Using a Model-Based Estimation (MBE) technique, a signal processing scheme has been developed that enables the echo signals from the pipe wall to be separated from the noise. This was implemented in a laboratory experimental program, featuring accelerated erosion/corrosion on the inner wall of a test pipe. The result was a reduction in the uncertainty in the wall thinning rate by a factor of four. This improvement enables a more rapid response by system operators to a change in plant conditions that could pose a pipe integrity problem. It also enables a rapid evaluation of the effectiveness of new corrosion inhibiting agents under plant operating conditions.

A model of acoustic transmission in the respiratory system.

PubMed

Wodicka, G R; Stevens, K N; Golub, H L; Cravalho, E G; Shannon, D C

1989-09-01

A theoretical model of sound transmission from within the respiratory tract to the chest wall due to the motion of the walls of the large airways was developed. The vocal tract, trachea, and the first five bronchial generations are represented over the frequency range from 100 to 600 Hz by an equivalent acoustic circuit. This circuit allows the estimation of the magnitude of airway wall motion in response to an acoustic perturbation at the mouth. The radiation of sound through the surrounding lung parenchyma is represented as a cylindrical wave in a homogeneous mixture of air bubbles in water. The effect of thermal losses associated with the polytropic compressions and expansions of these bubbles by the acoustic wave is included and the chest wall is represented as a massive boundary to the wave propagation. The model estimates the magnitude of acceleration over the extrathoracic trachea and at three locations on the posterior chest wall in the same vertical plane. The predicted spectral characteristics of transmission are consistent with previous experimental observations. This theoretical approach suggests that the locations of the spectral peaks are a strong function of the geometry and the wall properties of the airways, while the attenuation at higher frequencies is primarily associated with the absorption of sound in the parenchyma.

Distribution of the background gas in the MITICA accelerator

NASA Astrophysics Data System (ADS)

Sartori, E.; Dal Bello, S.; Serianni, G.; Sonato, P.

2013-02-01

MITICA is the ITER neutral beam test facility to be built in Padova for the generation of a 40A D- ion beam with a 16×5×16 array of 1280 beamlets accelerated to 1MV. The background gas pressure distribution and the particle flows inside MITICA accelerator are critical aspects for stripping losses, generation of secondary particles and beam non-uniformities. To keep the stripping losses in the extraction and acceleration stages reasonably low, the source pressure should be 0.3 Pa or less. The gas flow in MITICA accelerator is being studied using a 3D Finite Element code, named Avocado. The gas-wall interaction model is based on the cosine law, and the whole vacuum system geometry is represented by a view factor matrix based on surface discretization and gas property definitions. Pressure distribution and mutual fluxes are then solved linearly. In this paper the result of a numerical simulation is presented, showing the steady-state pressure distribution inside the accelerator when gas enters the system at room temperature. The accelerator model is limited to a horizontal slice 400 mm high (1/4 of the accelerator height). The pressure profile at solid walls and through the beamlet axis is obtained, allowing the evaluation and the discussion of the background gas distribution and nonuniformity. The particle flux at the inlet and outlet boundaries (namely the grounded grid apertures and the lateral conductances respectively) will be discussed.

Control of supersonic wind-tunnel noise by laminarization of nozzle-wall boundary layer

NASA Technical Reports Server (NTRS)

Beckwith, I. E.; Harvey, W. D.; Harris, J. E.; Holley, B. B.

1973-01-01

One of the principal design requirements for a quiet supersonic or hypersonic wind tunnel is to maintain laminar boundary layers on the nozzle walls and thereby reduce disturbance levels in the test flow. The conditions and apparent reasons for laminar boundary layers which have been observed during previous investigations on the walls of several nozzles for exit Mach numbers from 2 to 20 are reviewed. Based on these results, an analysis and an assessment of nozzle design requirements for laminar boundary layers including low Reynolds numbers, high acceleration, suction slots, wall temperature control, wall roughness, and area suction are presented.

Magnetic Shielding of the Acceleration Channel Walls in a Long-Life Hall Thruster

NASA Technical Reports Server (NTRS)

Mikellides, Ioannis G.; Katz, Ira; Hofer, Richard R.; Goebel, Dan M.; de Grys, Kristi; Mathers, Alex

2010-01-01

In a Qualification Life Test (QLT) of the BPT-4000 Hall thruster that recently accumulated greater than 10,000 h it was found that the erosion of the acceleration channel practically stopped after approximately 5,600 h. Numerical simulations of this thruster using a 2-D axisymmetric, magnetic field-aligned-mesh (MFAM) plasma solver reveal that the process that led to this significant reduction of the erosion was multifaceted. It is found that when the channel receded from its early-in-life geometry to its steady-state configuration several changes in the near-wall plasma and sheath were induced by the magnetic field that, collectively, constituted an effective shielding of the walls from any significant ion bombardment. Because all such changes in the behavior of the ionized gas near the eroding surfaces were caused by the topology of the magnetic field there, we term this process "magnetic shielding."

Response measurements for two building structures excited by noise from a large horizontal axis wind turbine generator

NASA Technical Reports Server (NTRS)

Hubbard, H. H.; Shepherd, K. P.

1984-01-01

Window and wall acceleration measurements and interior noise measurements ere made for two different building structures during excitation by noise from the WTS-4 horizontal axis wind turbine generator operating in a normal power generation mode. With turbine noise input pulses resulted in acceleration pulses for the wall and window elements of the two tests buildings. Response spectra suggest that natural vibration modes of the structures are excited. Responses of a house trailer were substantially greater than those for a building of sturdier construction. Peak acceleration values correlate well with similar data for houses excited by flyover noise from commercial and military airplanes and helicopters, and sonic booms from supersonic aircraft. Interior noise spectra have peaks at frequencies corresponding to structural vibration modes and room standing waves; and the levels for particular frequencies and locations can be higher than the outside levels.

Wall shear stress promotes intimal hyperplasia through the paracrine H2O2-mediated NOX-AKT-SVV axis.

PubMed

Zhang, Haolong; Yang, Zhipeng; Wang, Jing; Wang, Xuehu; Zhao, Yu; Zhu, Fangyu

2018-05-27

Oscillatory wall shear stress (WSS)-linked oxidative stress promotes intimal hyperplasia (IH) development, but the underlying mechanisms are not completely understood. We used an in vivo rabbit carotid arterial stenosis model representing different levels of WSS and found that WSS was increased at 1 month with 50% stenosis and was accompanied by VSMCs proliferation and interstitial collagen accumulation. Increased WSS promoted the expression of NOX, AKT, and survivin (SVV) and the proliferation/migration of VSMCs and reduced apoptosis. Our in vitro study suggested that H 2 O 2 promoted proliferation and migration while suppressing apoptosis in cultured human umbilical vascular endothelial cells. We demonstrated that the elevation of WSS promotes VSMC proliferation and migration through the H 2 O 2 -mediated NOX-AKT-SVV axis, thereby accelerating IH development. Copyright © 2017. Published by Elsevier Inc.

Clustering Of Left Ventricular Wall Motion Patterns

NASA Astrophysics Data System (ADS)

Bjelogrlic, Z.; Jakopin, J.; Gyergyek, L.

1982-11-01

A method for detection of wall regions with similar motion was presented. A model based on local direction information was used to measure the left ventricular wall motion from cineangiographic sequence. Three time functions were used to define segmental motion patterns: distance of a ventricular contour segment from the mean contour, the velocity of a segment and its acceleration. Motion patterns were clustered by the UPGMA algorithm and by an algorithm based on K-nearest neighboor classification rule.

Generalized Wall Function for Complex Turbulent Flows

NASA Technical Reports Server (NTRS)

Shih, Tsan-Hsing; Povinelli, Louis A.; Liu, Nan-Suey; Chen, Kuo-Huey

2000-01-01

A generalized wall function was proposed by Shih et al., (1999). It accounts the effect of pressure gradients on the flow near the wall. Theory shows that the effect of pressure gradients on the flow in the inertial sublayer is very significant and the standard wall function should be replaced by a generalized wall function. Since the theory is also valid for boundary layer flows toward separation, the generalized wall function may be applied to complex turbulent flows with acceleration, deceleration, separation and recirculation. This paper is to verify the generalized wall function with numerical simulations for boundary layer flows with various adverse and favorable pressure gradients, including flows about to separate. Furthermore, a general procedure of implementation of the generalized wall function for National Combustion Code (NCC) is described, it can be applied to both structured and unstructured CFD codes.

Computer simulations of Hall thrusters without wall losses designed using two permanent magnetic rings

NASA Astrophysics Data System (ADS)

Yongjie, Ding; Wuji, Peng; Liqiu, Wei; Guoshun, Sun; Hong, Li; Daren, Yu

2016-11-01

A type of Hall thruster without wall losses is designed by adding two permanent magnet rings in the magnetic circuit. The maximum strength of the magnetic field is set outside the channel. Discharge without wall losses is achieved by pushing down the magnetic field and adjusting the channel accordingly. The feasibility of the Hall thrusters without wall losses is verified via a numerical simulation. The simulation results show that the ionization region is located in the discharge channel and the acceleration region is outside the channel, which decreases the energy and flux of ions and electrons spattering on the wall. The power deposition on the channel walls can be reduced by approximately 30 times.

Magnetic booster fast ignition macron accelerator

NASA Astrophysics Data System (ADS)

Winterberg, F.

2006-11-01

A new fast ignition scheme was recently proposed where the ignition is done by the impact of a small solid projectile accelerated to velocities in excess of 108cm/s, with the acceleration done in two steps: first, by laser ablation of a flyer plate, and second by injecting the flyer plate into a conical duct. The two principal difficulties of this scheme are as follows: first, the required large mass ratio for the laser ablation rocket propelled flyer plate, and second, the Rayleigh-Taylor instability of the flyer plate during its implosive compression in the conical duct. To overcome these difficulties, it is suggested to accelerate a projectile by a magnetic fusion booster stage, made up of a dense, wall-confined magnetized plasma brought to thermonuclear temperatures. After ignition, this plasma undergoes a thermonuclear excursion greatly increasing its pressure, resulting in the explosion of a weakened segment of the wall, with the segment becoming a fast moving projectile. The maximum velocity this projectile can reach is the velocity of sound of the booster stage plasma, which at a temperature of 108K is of the order 108cm/s.

ACCELERATION INTEGRATING MEANS

DOEpatents

Wilkes, D.F.

1961-08-29

An acceleration responsive device is described. A housing has at one end normally open electrical contacts and contains a piston system with a first part of non-magnetic material having metering orifices in the side walls for forming an air bearing between it and the walls of the housing; this first piston part is normally held against the other end of the housing from the noted contacts by a second piston or reset part. The reset part is of partly magnetic material, is separable from the flrst piston part, and is positioned within the housing intermediate the contacts and the first piston part. A magnet carried by the housing imposes a retaining force upon the reset part, along with a helical compression spring that is between the reset part and the end with the contacts. When a predetermined acceleration level is attained, the reset part overcomes the bias or retaining force provided by the magnet and the spring'' snaps'' into a depression in the housing adjacent the contacts. The first piston part is then free to move toward the contacts with its movement responsive tc acceleration forces and the metering orifices. (AEC)

Advances in the genetic dissection of plant cell walls: tools and resources available in Miscanthus

PubMed Central

Slavov, Gancho; Allison, Gordon; Bosch, Maurice

2013-01-01

Tropical C4 grasses from the genus Miscanthus are believed to have great potential as biomass crops. However, Miscanthus species are essentially undomesticated, and genetic, molecular and bioinformatics tools are in very early stages of development. Furthermore, similar to other crops targeted as lignocellulosic feedstocks, the efficient utilization of biomass is hampered by our limited knowledge of the structural organization of the plant cell wall and the underlying genetic components that control this organization. The Institute of Biological, Environmental and Rural Sciences (IBERS) has assembled an extensive collection of germplasm for several species of Miscanthus. In addition, an integrated, multidisciplinary research programme at IBERS aims to inform accelerated breeding for biomass productivity and composition, while also generating fundamental knowledge. Here we review recent advances with respect to the genetic characterization of the cell wall in Miscanthus. First, we present a summary of recent and on-going biochemical studies, including prospects and limitations for the development of powerful phenotyping approaches. Second, we review current knowledge about genetic variation for cell wall characteristics of Miscanthus and illustrate how phenotypic data, combined with high-density arrays of single-nucleotide polymorphisms, are being used in genome-wide association studies to generate testable hypotheses and guide biological discovery. Finally, we provide an overview of the current knowledge about the molecular biology of cell wall biosynthesis in Miscanthus and closely related grasses, discuss the key conceptual and technological bottlenecks, and outline the short-term prospects for progress in this field. PMID:23847628

[Shielding design and detection of neutrons from medical and industrial electron accelerators--simple method of design calculation for neutron shielding].

PubMed

Nakamura, T; Uwamino, Y

1986-02-01

The neutron leakage from medical and industrial electron accelerators has become an important problem and its detection and shielding is being performed in their facilities. This study provides a new simple method of design calculation for neutron shielding of those electron accelerator facilities by dividing into the following five categories; neutron dose distribution in the accelerator room, neutron attenuation through the wall and the door in the accelerator room, neutron and secondary photon dose distributions in the maze, neutron and secondary photon attenuation through the door at the end of the maze, neutron leakage outside the facility-skyshine.

Applicability of a Bonner Shere technique for pulsed neutron in 120 GeV proton facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanami, T.; Hagiwara, M.; Iwase, H.

2008-02-01

The data on neutron spectra and intensity behind shielding are important for radiation safety design of high-energy accelerators since neutrons are capable of penetrating thick shielding and activating materials. Corresponding particle transport codes--that involve physics models of neutron and other particle production, transportation, and interaction--have been developed and used world-wide [1-8]. The results of these codes have been ensured through plenty of comparisons with experimental results taken in simple geometries. For neutron generation and transport, several related experiments have been performed to measure neutron spectra, attenuation length and reaction rates behind shielding walls of various thicknesses and materials in energymore » range up to several hundred of MeV [9-11]. The data have been used to benchmark--and modify if needed--the simulation modes and parameters in the codes, as well as the reference data for radiation safety design. To obtain such kind of data above several hundred of MeV, Japan-Fermi National Accelerator Laboratory (FNAL) collaboration for shielding experiments has been started in 2007, based on suggestion from the specialist meeting of shielding, Shielding Aspects of Target, Irradiation Facilities (SATIF), because of very limited data available in high-energy region (see, for example, [12]). As a part of this shielding experiment, a set of Bonner sphere (BS) was tested at the antiproton production target facility (pbar target station) at FNAL to obtain neutron spectra induced by a 120-GeV proton beam in concrete and iron shielding. Generally, utilization of an active detector around high-energy accelerators requires an improvement on its readout to overcome burst of secondary radiation since the accelerator delivers an intense beam to a target in a short period after relatively long acceleration period. In this paper, we employ BS for a spectrum measurement of neutrons that penetrate the shielding wall of the pbar target station in FNAL.« less

Design and Installation of a Field Ionization Test Chamber for Ion Thrusters

DTIC Science & Technology

2011-12-01

where F is thrust, m& is the mass flow rate of the propellant, and go is the standard acceleration due to gravity at sea level [1]. It provides a...only one graphene wall, and multi- walled CNT ( MWCNT ), which consist of multiple, concentric walls of graphene (Figure 9). One of the most unique...ionization chamber to ensure the mass flow rate going into the chamber matches the mass flow rate leaving it. 46 B. FIELD EMISSION AND FIELD

Unusual angiographic changes in an internal carotid artery pseudoaneurysm after infection in the deep neck space.

PubMed

Hayashi, Yasuhiko; Shima, Hiroshi; Miyashita, Katsuyoshi; Kinoshita, Masashi; Nakada, Mitsutoshi; Kida, Shinya; Hamada, Jun-ichiro

2008-05-01

A 48-year-old man presented with a pseudoaneurysm at the cervical portion of the left internal carotid artery (ICA) secondary to infection in the deep neck space. Magnetic resonance (MR) imaging demonstrated enhancement of the wall of the ICA and a pseudoaneurysm, considered to be sequelae of infection spread. ICA occlusion occurred on the next day resulting in sudden onset of right hemiparesis and motor aphasia. The ICA pseudoaneurysm shrank gradually and his neurological deficits improved with conservative therapy. One month later, he presented with aneurysm regrowth. The common carotid artery was occluded with Guglielmi detachable coils to block arterial flow into the pseudoaneurysm. There were no neurological complications. Marked enhancement of the ICA wall on computed tomography and MR imaging may indicate the possibility of vascular complications such as rupture, pseudoaneurysm development, or ICA occlusion, and consequent neurological deficits. ICA occlusion caused by spread of infection in the deep neck space may cause accelerated coagulopathy due to ICA wall inflammation.

Overexpression of OsEXPA8, a Root-Specific Gene, Improves Rice Growth and Root System Architecture by Facilitating Cell Extension

PubMed Central

Ma, Nana; Wang, Ying; Qiu, Shichun; Kang, Zhenhui; Che, Shugang; Wang, Guixue; Huang, Junli

2013-01-01

Expansins are unique plant cell wall proteins that are involved in cell wall modifications underlying many plant developmental processes. In this work, we investigated the possible biological role of the root-specific α-expansin gene OsEXPA8 in rice growth and development by generating transgenic plants. Overexpression of OsEXPA8 in rice plants yielded pleiotropic phenotypes of improved root system architecture (longer primary roots, more lateral roots and root hairs), increased plant height, enhanced leaf number and enlarged leaf size. Further study indicated that the average cell length in both leaf and root vascular bundles was enhanced, and the cell growth in suspension cultures was increased, which revealed the cellular basis for OsEXPA8-mediated rice plant growth acceleration. Expansins are thought to be a key factor required for cell enlargement and wall loosening. Atomic force microscopy (AFM) technology revealed that average wall stiffness values for 35S::OsEXPA8 transgenic suspension-cultured cells decreased over six-fold compared to wild-type counterparts during different growth phases. Moreover, a prominent change in the wall polymer composition of suspension cells was observed, and Fourier-transform infrared (FTIR) spectra revealed a relative increase in the ratios of the polysaccharide/lignin content in cell wall compositions of OsEXPA8 overexpressors. These results support a role for expansins in cell expansion and plant growth. PMID:24124527

Handbook of Supersonic Aerodynamics Volume 1

DTIC Science & Technology

1950-04-01

Appears in Z10 Publication Remarks •Mlc) *(lc) •Pile) Angle Potential function Helical angle of advance (propellers) Dimensionless Dependent on...heat of- combustion re(lc) N (cap) Nu. o(lc) Net Nozzle Normal (perpendicu- lar to longitudinal axis) ; normal (force) Nusselt ...Concepts ^ Concept Absolute Acceleration, angular Acceleration due to gravity Added; additional Adiabatic Adiabatic wall Advance, helical angle

Recent progress on the structure separation of single-wall carbon nanotubes

NASA Astrophysics Data System (ADS)

Cui, Jiaming; Yang, Dehua; Zeng, Xiang; Zhou, Naigen; Liu, Huaping

2017-11-01

The mass production of single-structure, single-wall carbon nanotubes (SWCNTs) with identical properties is critical for their basic research and technical applications in the fields of electronics, optics and optoelectronics. Great efforts have been made to control the structures of SWCNTs since their discovery. Recently, the structure separation of SWCNTs has been making great progress. Various solution-sorting methods have been developed to achieve not only the separation of metallic and semiconducting species, but also the sorting of distinct (n, m) single-chirality species and even their enantiomers. This progress would dramatically accelerate the application of SWCNTs in the next-generation electronic devices. Here, we review the recent progress in the structure sorting of SWCNTs and outline the challenges and prospects of the structure separation of SWCNTs.

Study of the seismic performance of hybrid A-frame micropile/MSE (mechanically stabilized earth) wall

NASA Astrophysics Data System (ADS)

Chen, Yumin; Zhang, Zhichao; Liu, Hanlong

2017-04-01

The Hybrid A-Frame Micropile/MSE (mechanically stabilized earth) Wall suitable for mountain roadways is put forward in this study: a pair of vertical and inclined micropiles goes through the backfill region of a highway MSE Wall from the road surface and are then anchored into the foundation. The pile cap and grade beam are placed on the pile tops, and then a road barrier is connected to the grade beam by connecting pieces. The MSE wall's global stability, local stability and impact resistance of the road barrier can be enhanced simultaneously by this design. In order to validate the serviceability of the hybrid A-frame micropile/MSE wall and the reliability of the numerical method, scale model tests and a corresponding numerical simulation were conducted. Then, the seismic performance of the MSE walls before and after reinforcement with micropiles was studied comparatively through numerical methods. The results indicate that the hybrid A-frame micropile/MSE wall can effectively control earthquake-induced deformation, differential settlement at the road surface, bearing pressure on the bottom and acceleration by means of a rigid-soft combination of micropiles and MSE. The accumulated displacement under earthquakes with amplitude of 0.1‒0.5 g is reduced by 36.3%‒46.5%, and the acceleration amplification factor on the top of the wall is reduced by 13.4%, 15.7% and 19.3% based on 0.1, 0.3 and 0.5 g input earthquake loading, respectively. In addition, the earthquake-induced failure mode of the MSE wall in steep terrain is the sliding of the MSE region along the backslope, while the micropiles effectively control the sliding trend. The maximum earthquake-induced pile bending moment is in the interface between MSE and slope foundation, so it is necessary to strengthen the reinforcement of the pile body in the interface. Hence, it is proven that the hybrid A-frame micropile/MSE wall system has good seismic performance.

Polymer dynamics under cylindrical confinement featuring a locally repulsive surface: A quasielastic neutron scattering study.

PubMed

Krutyeva, M; Pasini, S; Monkenbusch, M; Allgaier, J; Maiz, J; Mijangos, C; Hartmann-Azanza, B; Steinhart, M; Jalarvo, N; Richter, D

2017-05-28

We investigated the effect of intermediate cylindrical confinement with locally repulsive walls on the segmental and entanglement dynamics of a polymer melt by quasielastic neutron scattering. As a reference, the corresponding polymer melt was measured under identical conditions. The locally repulsive confinement was realized by hydrophilic anodic alumina nanopores with a diameter of 20 nm. The end-to-end distance of the hydrophobic infiltrated polyethylene-alt-propylene was close to this diameter. In the case of hard wall repulsion with negligible local attraction, several simulations predicted an acceleration of segmental dynamics close to the wall. Other than in attractive or neutral systems, where the segmental dynamics is slowed down, we found that the segmental dynamics in the nanopores is identical to the local mobility in the bulk. Even under very careful scrutiny, we could not find any acceleration of the surface-near segmental motion. On the larger time scale, the neutron spin-echo experiment showed that the Rouse relaxation was not altered by confinement effects. Also the entanglement dynamics was not affected. Thus at moderate confinement conditions, facilitated by locally repulsive walls, the dynamics remains as in the bulk melt, a result that is not so clear from simulations.

Inelastic collapse and near-wall localization of randomly accelerated particles.

PubMed

Belan, S; Chernykh, A; Lebedev, V; Falkovich, G

2016-05-01

Inelastic collapse of stochastic trajectories of a randomly accelerated particle moving in half-space z>0 has been discovered by McKean [J. Math. Kyoto Univ. 2, 227 (1963)] and then independently rediscovered by Cornell et al. [Phys. Rev. Lett. 81, 1142 (1998)PRLTAO0031-900710.1103/PhysRevLett.81.1142]. The essence of this phenomenon is that the particle arrives at the wall at z=0 with zero velocity after an infinite number of inelastic collisions if the restitution coefficient β of particle velocity is smaller than the critical value β_{c}=exp(-π/sqrt[3]). We demonstrate that inelastic collapse takes place also in a wide class of models with spatially inhomogeneous random forcing and, what is more, that the critical value β_{c} is universal. That class includes an important case of inertial particles in wall-bounded random flows. To establish how inelastic collapse influences the particle distribution, we derive the exact equilibrium probability density function ρ(z,v) for the particle position and velocity. The equilibrium distribution exists only at β<β_{c} and indicates that inelastic collapse does not necessarily imply near-wall localization.

Study on the influences of ionization region material arrangement on Hall thruster channel discharge characteristics

NASA Astrophysics Data System (ADS)

Xiang, HU; Ping, DUAN; Jilei, SONG; Wenqing, LI; Long, CHEN; Xingyu, BIAN

2018-02-01

There exists strong interaction between the plasma and channel wall in the Hall thruster, which greatly affects the discharge performance of the thruster. In this paper, a two-dimensional physical model is established based on the actual size of an Aton P70 Hall thruster discharge channel. The particle-in-cell simulation method is applied to study the influences of segmented low emissive graphite electrode biased with anode voltage on the discharge characteristics of the Hall thruster channel. The influences of segmented electrode placed at the ionization region on electric potential, ion number density, electron temperature, ionization rate, discharge current and specific impulse are discussed. The results show that, when segmented electrode is placed at the ionization region, the axial length of the acceleration region is shortened, the equipotential lines tend to be vertical with wall at the acceleration region, thus radial velocity of ions is reduced along with the wall corrosion. The axial position of the maximal electron temperature moves towards the exit with the expansion of ionization region. Furthermore, the electron-wall collision frequency and ionization rate also increase, the discharge current decreases and the specific impulse of the Hall thruster is slightly enhanced.

Polymer dynamics under cylindrical confinement featuring a locally repulsive surface: A quasielastic neutron scattering study

NASA Astrophysics Data System (ADS)

Krutyeva, M.; Pasini, S.; Monkenbusch, M.; Allgaier, J.; Maiz, J.; Mijangos, C.; Hartmann-Azanza, B.; Steinhart, M.; Jalarvo, N.; Richter, D.

2017-05-01

We investigated the effect of intermediate cylindrical confinement with locally repulsive walls on the segmental and entanglement dynamics of a polymer melt by quasielastic neutron scattering. As a reference, the corresponding polymer melt was measured under identical conditions. The locally repulsive confinement was realized by hydrophilic anodic alumina nanopores with a diameter of 20 nm. The end-to-end distance of the hydrophobic infiltrated polyethylene-alt-propylene was close to this diameter. In the case of hard wall repulsion with negligible local attraction, several simulations predicted an acceleration of segmental dynamics close to the wall. Other than in attractive or neutral systems, where the segmental dynamics is slowed down, we found that the segmental dynamics in the nanopores is identical to the local mobility in the bulk. Even under very careful scrutiny, we could not find any acceleration of the surface-near segmental motion. On the larger time scale, the neutron spin-echo experiment showed that the Rouse relaxation was not altered by confinement effects. Also the entanglement dynamics was not affected. Thus at moderate confinement conditions, facilitated by locally repulsive walls, the dynamics remains as in the bulk melt, a result that is not so clear from simulations.

A high-frequency lung injury mechanism in blunt thoracic impact.

PubMed

Grimal, Quentin; Naïli, Salah; Watzky, Alexandre

2005-06-01

When a mechanical load is applied very rapidly to the thoracic wall, part of the internal damage is suspected to be due to a "high-frequency" injury mechanism, that is, a phenomenon in which waves are involved. This paper addresses a specific high-frequency mechanism for lung injury in which a stress wave is generated through rapid acceleration of the body wall. Displacement-related injuries, which are rather "low-frequency" phenomena, are not considered. The present work was done in the context of assessing behind armor blunt trauma (injury to thoracic organs occurring when a bullet is stopped by a body armor) through mathematical modeling. One aspect of the thorax response to high-speed blunt impact and an associated injury mechanism are investigated based on an idealized model of thorax and a set of computations presented in previous papers. The injury mechanism considered elucidates a possible mathematical relationship between the acceleration at the surface of the thoracic wall and the occurrence of lung injury.

A Concept for Directly Coupled Pulsed Electromagnetic Acceleration of Plasmas

NASA Technical Reports Server (NTRS)

Thio, Y.C. Francis; Cassibry, Jason T.; Eskridge, Richard; Smith, James; Wu, S. T.; Rodgers, Stephen L. (Technical Monitor)

2001-01-01

Plasma jets with high momentum flux density are required for a variety of applications in propulsion research. Methods of producing these plasma jets are being investigated at NASA Marshall Space Flight Center. The experimental goal in the immediate future is to develop plasma accelerators which are capable of producing plasma jets with momentum flux density represented by velocities up to 200 km/s and ion density up to 10(exp 24) per cu m, with sufficient precision and reproducibility in their properties, and with sufficiently high efficiency. The jets must be sufficiently focused to allow them to be transported over several meters. A plasma accelerator concept is presented that might be able to meet these requirements. It is a self-switching, shaped coaxial pulsed plasma thruster, with focusing of the plasma flow by shaping muzzle current distribution as in plasma focus devices, and by mechanical tapering of the gun walls. Some 2-D MHD modeling in support of the conceptual design will be presented.

Super free fall for a container composed of diverging flat plates

NASA Astrophysics Data System (ADS)

Medina, A.; Torres, A.; Peralta, S.; Weidman, P. D.

2010-11-01

We have analyzed experimentally and theoretically the characteristics of the upper free surface of a liquid column released from rest in a vertical container whose cross-section opens slowly in the downward direction. In distinction with the work of Villermaux and Pomeau (2010) for a conical container, we consider a container composed of slightly inclined flat surfaces. At small times for which viscous effects can be neglected, the free surface moves downward with an acceleration larger than gravity. The existence of a nipple centered on the upper free surface with amplitude an increasing function of time is observed. A one-dimensional model of the initial acceleration for flat, slightly expanding walls reproduces the observed super free fall experiments fairly well. Details of the nipple development will be presented.

Field Emission in Superconducting Accelerators: Instrumented Measurements for Its Understanding and Mitigation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geng, Rongli; Freyberger, Arne P.; Legg, Robert A.

Several new accelerator projects are adopting superconducting accelerator technology. When accelerating cavities maintain high RF gradients, field emission, the emission of electrons from cavity walls, can occur and may impact operational cavity gradient, radiological environment via activated components, and reliability. In this talk, we will discuss instrumented measurements of field emission from the two 1.1 GeV superconducting continuous wave (CW) linacs in CEBAF. The goal is to improve the understanding of field emission sources originating from cryomodule production, installation and operation. Such basic knowledge is needed in guiding field emission control, mitigation, and reduction toward high gradient and reliable operationmore » of superconducting accelerators.« less

Magnetic Compression Experiment at General Fusion with Simulation Results

NASA Astrophysics Data System (ADS)

Dunlea, Carl; Khalzov, Ivan; Hirose, Akira; Xiao, Chijin; Fusion Team, General

2017-10-01

The magnetic compression experiment at GF was a repetitive non-destructive test to study plasma physics applicable to Magnetic Target Fusion compression. A spheromak compact torus (CT) is formed with a co-axial gun into a containment region with an hour-glass shaped inner flux conserver, and an insulating outer wall. External coil currents keep the CT off the outer wall (levitation) and then rapidly compress it inwards. The optimal external coil configuration greatly improved both the levitated CT lifetime and the rate of shots with good compressional flux conservation. As confirmed by spectrometer data, the improved levitation field profile reduced plasma impurity levels by suppressing the interaction between plasma and the insulating outer wall during the formation process. We developed an energy and toroidal flux conserving finite element axisymmetric MHD code to study CT formation and compression. The Braginskii MHD equations with anisotropic heat conduction were implemented. To simulate plasma / insulating wall interaction, we couple the vacuum field solution in the insulating region to the full MHD solution in the remainder of the domain. We see good agreement between simulation and experiment results. Partly funded by NSERC and MITACS Accelerate.

Quiet Clean Short-haul Experimental Engine (QCSEE); acoustic performance of a 50.8-cm (20 inch) diameter variable pitch fan and inlet, test results and analysis, volume 1

NASA Technical Reports Server (NTRS)

Bilwakesh, K. R.; Clemons, A.; Stimpert, D. L.

1979-01-01

Tests were run both in forward and in reverse thrust modes with a bellmouth inlet, five accelerating inlets (one hard wall and four treated) with a design throat Mach number of 0.79 at the takeoff condition, and four low Mach inlets (one hard wall and three treated) with a design throat Mach number of 0.6 at the takeoff condition. Unsuppressed and suppressed inlet radiated noise levels were measured at conditions representative of QCSEE takeoff, approach, and reverse thrust operations. Measured aerodynamic performance of the accelerating inlet is also included. The test objectives, facility, configurations, are described as well as the data analysis, results, and comparisons.

Ion behavior in low-power magnetically shielded and unshielded Hall thrusters

NASA Astrophysics Data System (ADS)

Grimaud, L.; Mazouffre, S.

2017-05-01

Magnetically shielded Hall thrusters achieve a longer lifespan than traditional Hall thrusters by reducing wall erosion. The lower erosion rate is attributed to a reduction of the high energy ion population impacting the walls. To investigate this phenomenon, the ion velocity distribution functions are measured with laser induced fluorescence at several points of interest in the magnetically shielded ISCT200-MS and the unshielded ISCT200-US Hall thrusters. The center of the discharge channel is probed to highlight the difference in plasma positioning between the shielded and unshielded thrusters. Erosion phenomena are investigated by taking measurements of the ion velocity distribution near the inner and outer wall as well as above the magnetic poles where some erosion is observed. The resulting distribution functions show a displacement of the acceleration region from inside the channel in the unshielded thruster to downstream of the exit plane in the ISCT200-MS. Near the walls, the unshielded thruster displays both a higher relative ion density as well as a significant fraction of the ions with velocities toward the walls compared to the shielded thruster. Higher proportions of high velocity ions are also observed. Those results are in accordance with the reduced erosion observed. Both shielded and unshielded thrusters have large populations of ions impacting the magnetic poles. The mechanism through which those ions are accelerated toward the magnetic poles has so far not been explained.

Study of the Accelerating Channel Wall Property Influence on the Hall Thruster Discharge Characteristics

DTIC Science & Technology

2004-11-01

Hall thruster characteristics there was prepared Hall thruster model of the SPT-100 type for these experiments and there were manufactured the required discharge chamber parts (rings) made of the Russian BN-SiO2 (borosil) ceramics and of the Russian AIN-BN (ABN) and Western ABN ceramics having secondary electron emission yield (SEEY) different from that one for borosil. These parts were replaceable during experiments. Thruster model was equipped by set of the near wall probes mounted at external discharge chamber wall. There was made characterization

Effect of gravitational acceleration, hypokinesia and hypodynamia on the structure of the intestinal vascular bed

NASA Technical Reports Server (NTRS)

Nikitin, M. V.

1980-01-01

A series of experiments comparing single and combined effects of hypokinesia and gravitational acceleration on morphology of intestinal blood vessels are discussed. Results indicate that hypokinesia has a whole body nonspecific effect reflected even in an organ whose activity shows little or no change due to hypokinesia. In early hypokinetic stages blood redistribution caused anorexia, intestinal atonia, and secretory disruption. Destructive changes from further exposure include aneurisms, varicoses, extravascular movement of blood elements, and vascular wall muscle fiber degeneration. The effect of acceleration is greatest in the ventrodorsal direction. Changes due to acceleration then hypokinesia are like those due to hypokinesia alone; changes due to acceleration before and after hypokinesia are like those due to acceleration. Adaptation raises acceleration tolerance but the effects do not survive four-week hypokinesia.

A preliminary design of the collinear dielectric wakefield accelerator

NASA Astrophysics Data System (ADS)

Zholents, A.; Gai, W.; Doran, S.; Lindberg, R.; Power, J. G.; Strelnikov, N.; Sun, Y.; Trakhtenberg, E.; Vasserman, I.; Jing, C.; Kanareykin, A.; Li, Y.; Gao, Q.; Shchegolkov, D. Y.; Simakov, E. I.

2016-09-01

A preliminary design of the multi-meter long collinear dielectric wakefield accelerator that achieves a highly efficient transfer of the drive bunch energy to the wakefields and to the witness bunch is considered. It is made from 0.5 m long accelerator modules containing a vacuum chamber with dielectric-lined walls, a quadrupole wiggler, an rf coupler, and BPM assembly. The single bunch breakup instability is a major limiting factor for accelerator efficiency, and the BNS damping is applied to obtain the stable multi-meter long propagation of a drive bunch. Numerical simulations using a 6D particle tracking computer code are performed and tolerances to various errors are defined.

Movement of the Melt Metal Layer under Conditions Typical of Transient Events in ITER

NASA Astrophysics Data System (ADS)

Poznyak, I. M.; Safronov, V. M.; Zybenko, V. Yu.

2017-12-01

During the operation of ITER, protective coatings of the divertor and the first wall will be exposed to significant plasma heat loads which may cause a huge erosion. One of the major failure mechanisms of metallic armor is diminution of their thickness due to the melt layer displacement. New experimental data are required in order to develop and validate physical models of the melt layer movement. The paper presents the experiments where metal targets were irradiated by a plasma stream at the quasi-stationary high-current plasma accelerator QSPA-T. The obtained data allow one to determine the velocity and acceleration of the melt layer at various distances from the plasma stream axis. The force causing the radial movement of the melt layer is shown to create an acceleration whose order of magnitude is 1000g. The pressure gradient is not responsible for creating this large acceleration. To investigate the melt layer movement under a known force, the experiment with a rotating target was carried out. The influence of centrifugal and Coriolis forces led to appearance of curved elongated waves on the surface. The surface profile changed: there is no hill in the central part of the erosion crater in contrast to the stationary target. The experimental data clarify the trends in the melt motion that are required for development of theoretical models.

Development of a new instrument for direct skin friction measurements

NASA Technical Reports Server (NTRS)

Vakili, A. D.; Wu, J. M.

1986-01-01

A device developed for the direct measurement of wall shear stress generated by flows is described. Simple and symmetric in design with optional small moving mass and no internal friction, the features employed in the design eliminate most of the difficulties associated with the traditional floating element balances. The device is basically small and can be made in various sizes. Vibration problems associated with the floating element skin friction balances were found to be minimized due to the design symmetry and optional damping provided. The design eliminates or reduces the errors associated with conventional floating element devices: such as errors due to gaps, pressure gradient, acceleration, heat transfer, and temperature change. The instrument is equipped with various sensing systems and the output signal is a linear function of the wall shear stress. Dynamic measurements could be made in a limited range and measurements in liquids could be performed readily. Measurement made in the three different tunnels show excellent agreement with data obtained by the floating element devices and other techniques.

Hydrogen film/conductive cooling

NASA Technical Reports Server (NTRS)

Ewen, R. L.

1972-01-01

Small scale nozzle tests using heated nitrogen were run to obtain effectiveness and wall heat transfer data with hydrogen film cooling. Effectiveness data are compared with an entrainment model developed from planar, unaccelerated flow data. Results indicate significant effects due to flow turning and acceleration. With injection velocity effects accounted for explicitly, heat transfer correlation coefficients were found to be the same with and without film cooling when properties are evaluated at an appropriate reference temperature for the local gas composition defined by the coolant effectiveness. A design study for an O2/H2 application with 300 psia (207 N/sq cm) chamber pressure and 1500 lbs (6670 N) thrust indicates an adiabatic wall design requires 4 to 5 percent of the total flow as hydrogen film cooling. Internal regenerative cooling designs were found to offer no reduction in coolant requirements.

RF plasma modeling of the Linac4 H- ion source

NASA Astrophysics Data System (ADS)

Mattei, S.; Ohta, M.; Hatayama, A.; Lettry, J.; Kawamura, Y.; Yasumoto, M.; Schmitzer, C.

2013-02-01

This study focuses on the modelling of the ICP RF-plasma in the Linac4 H- ion source currently being constructed at CERN. A self-consistent model of the plasma dynamics with the RF electromagnetic field has been developed by a PIC-MCC method. In this paper, the model is applied to the analysis of a low density plasma discharge initiation, with particular interest on the effect of the external magnetic field on the plasma properties, such as wall loss, electron density and electron energy. The employment of a multi-cusp magnetic field effectively limits the wall losses, particularly in the radial direction. Preliminary results however indicate that a reduced heating efficiency results in such a configuration. The effect is possibly due to trapping of electrons in the multi-cusp magnetic field, preventing their continuous acceleration in the azimuthal direction.

The logarithmic and power law behaviors of the accelerating, turbulent thermal boundary layer

NASA Astrophysics Data System (ADS)

Castillo, Luciano; Hussain, Fazle

2017-02-01

Direct numerical simulation of spatially evolving thermal turbulent boundary layers with strong favorable pressure gradient (FPG) shows that the thermal fluctuation intensity, θ' + and the Reynolds shear stress, u'v'¯+ exhibit a logarithmic behavior spanning the meso-layer (e.g., 50 ≤y+≤170 ). However, the mean thermal profile is not logarithmic even in the zero pressure gradient (ZPG) region; instead, it follows a power law. The maxima of u' 2 ¯+ and v'θ'¯+ change little with the strength of acceleration, while v'+, w'+, and u'v'¯+ continue to decay in the flow direction. Furthermore, θ'+ and u'θ'¯+ surprisingly experience changes from constants in ZPG to sharp rises in the FPG region. Such behavior appears to be due to squashing of the streaks which decreases the streak flank angle below the critical value for "transient growth" generation of streamwise vortices, shutting down production [W. Schoppa and F. Hussain, "Coherent structure generation near-wall turbulence," J. Fluid Mech. 453, 57-108 (2002)]. The streamwise vortices near the wall, although shrink because of stretching, simultaneously, also become weaker as the structures are progressively pushed farther down to the more viscous region near the wall. While the vortical structures decay rapidly in accelerating flows, the thermal field does not—nullifying the myth that both the thermal and velocity fields are similar.

Spatial gradients in cell wall composition and transcriptional profiles along elongating maize internodes

PubMed Central

2014-01-01

Background The elongating maize internode represents a useful system for following development of cell walls in vegetative cells in the Poaceae family. Elongating internodes can be divided into four developmental zones, namely the basal intercalary meristem, above which are found the elongation, transition and maturation zones. Cells in the basal meristem and elongation zones contain mainly primary walls, while secondary cell wall deposition accelerates in the transition zone and predominates in the maturation zone. Results The major wall components cellulose, lignin and glucuronoarabinoxylan (GAX) increased without any abrupt changes across the elongation, transition and maturation zones, although GAX appeared to increase more between the elongation and transition zones. Microarray analyses show that transcript abundance of key glycosyl transferase genes known to be involved in wall synthesis or re-modelling did not match the increases in cellulose, GAX and lignin. Rather, transcript levels of many of these genes were low in the meristematic and elongation zones, quickly increased to maximal levels in the transition zone and lower sections of the maturation zone, and generally decreased in the upper maturation zone sections. Genes with transcript profiles showing this pattern included secondary cell wall CesA genes, GT43 genes, some β-expansins, UDP-Xylose synthase and UDP-Glucose pyrophosphorylase, some xyloglucan endotransglycosylases/hydrolases, genes involved in monolignol biosynthesis, and NAM and MYB transcription factor genes. Conclusions The data indicated that the enzymic products of genes involved in cell wall synthesis and modification remain active right along the maturation zone of elongating maize internodes, despite the fact that corresponding transcript levels peak earlier, near or in the transition zone. PMID:24423166

Plasma-wall interaction in laser inertial fusion reactors: novel proposals for radiation tests of first wall materials

NASA Astrophysics Data System (ADS)

Alvarez Ruiz, J.; Rivera, A.; Mima, K.; Garoz, D.; Gonzalez-Arrabal, R.; Gordillo, N.; Fuchs, J.; Tanaka, K.; Fernández, I.; Briones, F.; Perlado, J.

2012-12-01

Dry-wall laser inertial fusion (LIF) chambers will have to withstand strong bursts of fast charged particles which will deposit tens of kJ m-2 and implant more than 1018 particles m-2 in a few microseconds at a repetition rate of some Hz. Large chamber dimensions and resistant plasma-facing materials must be combined to guarantee the chamber performance as long as possible under the expected threats: heating, fatigue, cracking, formation of defects, retention of light species, swelling and erosion. Current and novel radiation resistant materials for the first wall need to be validated under realistic conditions. However, at present there is a lack of facilities which can reproduce such ion environments. This contribution proposes the use of ultra-intense lasers and high-intense pulsed ion beams (HIPIB) to recreate the plasma conditions in LIF reactors. By target normal sheath acceleration, ultra-intense lasers can generate very short and energetic ion pulses with a spectral distribution similar to that of the inertial fusion ion bursts, suitable to validate fusion materials and to investigate the barely known propagation of those bursts through background plasmas/gases present in the reactor chamber. HIPIB technologies, initially developed for inertial fusion driver systems, provide huge intensity pulses which meet the irradiation conditions expected in the first wall of LIF chambers and thus can be used for the validation of materials too.

Particle Trajectories in Rotating Wall Cell Culture Devices

NASA Technical Reports Server (NTRS)

Ramachandran N.; Downey, J. P.

1999-01-01

Cell cultures are extremely important to the medical community since such cultures provide an opportunity to perform research on human tissue without the concerns inherent in experiments on individual humans. Development of cells in cultures has been found to be greatly influenced by the conditions of the culture. Much work has focused on the effect of the motions of cells in the culture relative to the solution. Recently rotating wall vessels have been used with success in achieving improved cellular cultures. Speculation and limited research have focused on the low shear environment and the ability of rotating vessels to keep cells suspended in solution rather than floating or sedimenting as the primary reasons for the improved cellular cultures using these devices. It is widely believed that the cultures obtained using a rotating wall vessel simulates to some degree the effect of microgravity on cultures. It has also been speculated that the microgravity environment may provide the ideal acceleration environment for culturing of cellular tissues due to the nearly negligible levels of sedimentation and shear possible. This work predicts particle trajectories of cells in rotating wall vessels of cylindrical and annular design consistent with the estimated properties of typical cellular cultures. Estimates of the shear encountered by cells in solution and the interactions with walls are studied. Comparisons of potential experiments in ground and microgravity environments are performed.

Beryllium liner implosion experiments on the Z accelerator in preparation for magnetized liner inertial fusiona)

NASA Astrophysics Data System (ADS)

McBride, R. D.; Martin, M. R.; Lemke, R. W.; Greenly, J. B.; Jennings, C. A.; Rovang, D. C.; Sinars, D. B.; Cuneo, M. E.; Herrmann, M. C.; Slutz, S. A.; Nakhleh, C. W.; Ryutov, D. D.; Davis, J.-P.; Flicker, D. G.; Blue, B. E.; Tomlinson, K.; Schroen, D.; Stamm, R. M.; Smith, G. E.; Moore, J. K.; Rogers, T. J.; Robertson, G. K.; Kamm, R. J.; Smith, I. C.; Savage, M.; Stygar, W. A.; Rochau, G. A.; Jones, M.; Lopez, M. R.; Porter, J. L.; Matzen, M. K.

2013-05-01

Multiple experimental campaigns have been executed to study the implosions of initially solid beryllium (Be) liners (tubes) on the Z pulsed-power accelerator. The implosions were driven by current pulses that rose from 0 to 20 MA in either 100 or 200 ns (200 ns for pulse shaping experiments). These studies were conducted in support of the recently proposed Magnetized Liner Inertial Fusion concept [Slutz et al., Phys. Plasmas 17, 056303 (2010)], as well as for exploring novel equation-of-state measurement techniques. The experiments used thick-walled liners that had an aspect ratio (initial outer radius divided by initial wall thickness) of either 3.2, 4, or 6. From these studies, we present three new primary results. First, we present radiographic images of imploding Be liners, where each liner contained a thin aluminum sleeve for enhancing the contrast and visibility of the liner's inner surface in the images. These images allow us to assess the stability of the liner's inner surface more accurately and more directly than was previously possible. Second, we present radiographic images taken early in the implosion (prior to any motion of the liner's inner surface) of a shockwave propagating radially inward through the liner wall. Radial mass density profiles from these shock compression experiments are contrasted with profiles from experiments where the Z accelerator's pulse shaping capabilities were used to achieve shockless ("quasi-isentropic") liner compression. Third, we present "micro-Ḃ" measurements of azimuthal magnetic field penetration into the initially vacuum-filled interior of a shocked liner. Our measurements and simulations reveal that the penetration commences shortly after the shockwave breaks out from the liner's inner surface. The field then accelerates this low-density "precursor" plasma to the axis of symmetry.

Beryllium liner implosion experiments on the Z accelerator in preparation for magnetized liner inertial fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

McBride, R. D.; Martin, M. R.; Lemke, R. W.

Multiple experimental campaigns have been executed to study the implosions of initially solid beryllium (Be) liners (tubes) on the Z pulsed-power accelerator. The implosions were driven by current pulses that rose from 0 to 20 MA in either 100 or 200 ns (200 ns for pulse shaping experiments). These studies were conducted in support of the recently proposed Magnetized Liner Inertial Fusion concept [Slutz et al., Phys. Plasmas 17, 056303 (2010)], as well as for exploring novel equation-of-state measurement techniques. The experiments used thick-walled liners that had an aspect ratio (initial outer radius divided by initial wall thickness) of eithermore » 3.2, 4, or 6. From these studies, we present three new primary results. First, we present radiographic images of imploding Be liners, where each liner contained a thin aluminum sleeve for enhancing the contrast and visibility of the liner's inner surface in the images. These images allow us to assess the stability of the liner's inner surface more accurately and more directly than was previously possible. Second, we present radiographic images taken early in the implosion (prior to any motion of the liner's inner surface) of a shockwave propagating radially inward through the liner wall. Radial mass density profiles from these shock compression experiments are contrasted with profiles from experiments where the Z accelerator's pulse shaping capabilities were used to achieve shockless (“quasi-isentropic”) liner compression. Third, we present “micro-B-dot ” measurements of azimuthal magnetic field penetration into the initially vacuum-filled interior of a shocked liner. Our measurements and simulations reveal that the penetration commences shortly after the shockwave breaks out from the liner's inner surface. The field then accelerates this low-density “precursor” plasma to the axis of symmetry.« less

Carbon nanotubes with high bone-tissue compatibility and bone-formation acceleration effects.

PubMed

Usui, Yuki; Aoki, Kaoru; Narita, Nobuyo; Murakami, Narumichi; Nakamura, Isao; Nakamura, Koichi; Ishigaki, Norio; Yamazaki, Hiroshi; Horiuchi, Hiroshi; Kato, Hiroyuki; Taruta, Seiichi; Kim, Yoong Ahm; Endo, Morinobu; Saito, Naoto

2008-02-01

Carbon nanotubes (CNTs) have been used in various fields as composites with other substances or alone to develop highly functional materials. CNTs hold great interest with respect to biomaterials, particularly those to be positioned in contact with bone such as prostheses for arthroplasty, plates or screws for fracture fixation, drug delivery systems, and scaffolding for bone regeneration. Accordingly, bone-tissue compatibility of CNTs and CNT influence on bone formation are important issues, but the effects of CNTs on bone have not been delineated. Here, it is found that multi-walled CNTs adjoining bone induce little local inflammatory reaction, show high bone-tissue compatibility, permit bone repair, become integrated into new bone, and accelerate bone formation stimulated by recombinant human bone morphogenetic protein-2 (rhBMP-2). This study provides an initial investigational basis for CNTs in biomaterials that are used adjacent to bone, including uses to promote bone regeneration. These findings should encourage development of clinical treatment modalities involving CNTs.

Feasibility study of an aerial manipulator interacting with a vertical wall

DTIC Science & Technology

2017-06-01

each blade . Some tests are run with different levels of PWM input and the resultant angular acceleration in each case is measured with the motion...Helicopter Near a Vertical Surface ...................29 Figure 15. Near-Wall Moment for a Single Blade Helicopter. Source: [30]. .............30...with canted propellers is proposed, so that each blade applies thrust with components in the vertical and in the horizontal plane. In Figure 10

Polymer dynamics under cylindrical confinement featuring a locally repulsive surface: A quasielastic neutron scattering study

DOE PAGES

Krutyeva, M.; Pasini, S.; Monkenbusch, M.; ...

2017-02-02

We investigated the effect of intermediate cylindrical confinement with locally repulsive walls on the segmental and entanglement dynamics of a polymer melt by quasielastic neutron scattering. As a reference, we measured the corresponding polymer melt under identical conditions. The locally repulsive confinement was realized by hydrophilic anodic alumina nanopores with a diameter of 20 nm. The end-to-end distance of the hydrophobic infiltrated polyethylene-alt-propylene was close to this diameter. In the case of hard wall repulsion with negligible local attraction, several simulations predicted an acceleration of segmental dynamics close to the wall. Other than in attractive or neutral systems, where themore » segmental dynamics is slowed down, we found that the segmental dynamics in the nanopores is identical to the local mobility in the bulk. Even under very careful scrutiny, we could not find any acceleration of the surface-near segmental motion. On the larger time scale, the neutron spin-echo experiment showed that the Rouse relaxation was not altered by confinement effects. Moreover, the entanglement dynamics was not affected. Thus at moderate confinement conditions, facilitated by locally repulsive walls, the dynamics remains as in the bulk melt, a result that is not so clear from simulations.« less

Corrosion monitoring using high-frequency guided ultrasonic waves

NASA Astrophysics Data System (ADS)

Fromme, Paul

2014-02-01

Corrosion develops due to adverse environmental conditions during the life cycle of a range of industrial structures, e.g., offshore oil platforms, ships, and desalination plants. Both pitting corrosion and generalized corrosion leading to wall thickness loss can cause the degradation of the structural integrity. The nondestructive detection and monitoring of corrosion damage in difficult to access areas can be achieved using high frequency guided waves propagating along the structure from accessible areas. Using standard ultrasonic transducers with single sided access to the structure, guided wave modes were generated that penetrate through the complete thickness of the structure. The wave propagation and interference of the different guided wave modes depends on the thickness of the structure. Laboratory experiments were conducted and the wall thickness reduced by consecutive milling of the steel structure. Further measurements were conducted using accelerated corrosion in a salt water bath and the damage severity monitored. From the measured signal change due to the wave mode interference the wall thickness reduction was monitored. The high frequency guided waves have the potential for corrosion damage monitoring at critical and difficult to access locations from a stand-off distance.

Vibration characteristics of walls and a plate glass window representative of those of a wood-frame house

NASA Technical Reports Server (NTRS)

Carden, H. D.

1979-01-01

Mechanical excitation was used, and measurements of acceleration response, natural frequencies, and nodal patterns were performed. Results indicate that the wall sections and the complete wall did not act as a unit in responding to sinusoidal vibration inputs. Calculated frequencies of the components that account for this independent behavior of the studs and face sheets agreed resonably well with experimental frequencies. Experimental vibrations of the plate glass window agreed with the calculated behavior, and responses of the window exposed to airplane flyover noise were readily correlated with the test results.

Peristaltic flow of Powell-Eyring fluid in curved channel with heat transfer: A useful application in biomedicine.

PubMed

Hina, S; Mustafa, M; Hayat, T; Alsaedi, A

2016-10-01

In this work, we explore the heat transfer characteristics in the peristaltic transport of Powell-Eyring fluid inside a curved channel with complaint walls. The study has motivation toward the understanding of blood flow in microcirculatory system. Formulation is developed in the existence of velocity slip and temperature jump conditions. Perturbation approach has been utilized to present series expressions of axial velocity and temperature distributions. Streamlines are prepared to analyze the interesting phenomenon of trapping. Moreover, the plots of heat transfer coefficient for a broad range of embedded parameters are presented and discussed. The results indicate that slip effects substantially influence the velocity and temperature distributions. Axial flow accelerates when slip parameter is incremented. Temperature rises and wall heat flux grows when viscous dissipation effect is strengthened. In contrast to the planar channels, here velocity and temperature functions do not exhibit symmetry with respect to the central line. In addition, bolus size and its shape are different in upper and lower portions of the channel. Heat transfer coefficient enlarges when the curvature effects are reduced. The behaviors of wall tension and wall mass parameters on the profiles are qualitatively similar. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

The three-dimensional simulation analysis of dynamic response on perforated strings

NASA Astrophysics Data System (ADS)

Li, M. F.; Liu, H. F.; Dou, Y. H.; Cao, L. H.; Liu, Y. X.

2018-06-01

It analyzes the dynamic response and stresses of perforating tubular string to detonating impact load in oil-gas well in ANSYS, obtains the response of vibration displacement, velocity and acceleration of perforating tubularstring caused by detonating impact load, finds the influence of the length and wall thickness of perforating tubular string to working stresses. The result shows that:when the detonating impact load exerts the perforating tubular string with compressive and tensile axial force alternatively;the vibration displacement, velocity and acceleration of perfora-ting tubular string change periodically at same cycle;the closer to the perforating gun, the larger the amplitude of vi-bration velocity and acceleration;the closer to the packer the smaller the vibration displacement, the larger the work-ing equivalent stress of perforating tubular string;the longer or the thicker the perforating tubular string, the smaller the working equivalent stress and the higher the strength safety. Therefore, it uses the damping tube between packer and perforating gun as well as thick walled tubing to increase the strength safety of perforating tubular string.

Detection and Tracking of Moving Targets Behind Cluttered Environments Using Compressive Sensing

NASA Astrophysics Data System (ADS)

Dang, Vinh Quang

Detection and tracking of moving targets (target's motion, vibration, etc.) in cluttered environments have been receiving much attention in numerous applications, such as disaster search-and-rescue, law enforcement, urban warfare, etc. One of the popular techniques is the use of stepped frequency continuous wave radar due to its low cost and complexity. However, the stepped frequency radar suffers from long data acquisition time. This dissertation focuses on detection and tracking of moving targets and vibration rates of stationary targets behind cluttered medium such as wall using stepped frequency radar enhanced by compressive sensing. The application of compressive sensing enables the reconstruction of the target space using fewer random frequencies, which decreases the acquisition time. Hardware-accelerated parallelization on GPU is investigated for the Orthogonal Matching Pursuit reconstruction algorithm. For simulation purpose, two hybrid methods have been developed to calculate the scattered fields from the targets through the wall approaching the antenna system, and to convert the incoming fields into voltage signals at terminals of the receive antenna. The first method is developed based on the plane wave spectrum approach for calculating the scattered fields of targets behind the wall. The method uses Fast Multiple Method (FMM) to calculate scattered fields on a particular source plane, decomposes them into plane wave components, and propagates the plane wave spectrum through the wall by integrating wall transmission coefficients before constructing the fields on a desired observation plane. The second method allows one to calculate the complex output voltage at terminals of a receiving antenna which fully takes into account the antenna effects. This method adopts the concept of complex antenna factor in Electromagnetic Compatibility (EMC) community for its calculation.

Effect of vaginal distention on elastic fiber synthesis and matrix degradation in the vaginal wall: potential role in the pathogenesis of pelvic organ prolapse

PubMed Central

Rahn, D. D.; Acevedo, J. F.; Word, R. A.

2008-01-01

Matrix metalloprotease (MMP) activity is increased in the postpartum vagina of wild-type (WT) animals. This degradative activity is also accompanied by a burst in elastic fiber synthesis and assembly. The mechanisms that precipitate these changes are unclear. The goals of this study were to determine how vaginal distention (such as in parturition) affects elastic fiber homeostasis in the vaginal wall and the potential significance of these changes in the pathogenesis of pelvic organ prolapse. Vaginal distention with a balloon simulating parturition resulted in increased MMP-2 and MMP-9 activity in the vaginal wall of nonpregnant and pregnant animals. This was accompanied by visible fragmented and disrupted elastic fibers in the vaginal wall. In nonpregnant animals, the abundant amounts of tropoelastin and fibulin-5 in the vagina were not increased further by distention. In contrast, in pregnant animals, the suppressed levels of both proteins were increased 3-fold after vaginal distention. Distention performed in fibulin-5-deficient (Fbln5−/−) mice with defective elastic fiber synthesis and assembly induced accelerated pelvic organ prolapse, which never recovered. We conclude that, in pregnant mice, vaginal distention results in increased protease activity in the vaginal wall but also increased synthesis of proteins important for elastic fiber assembly. Distention may thereby contribute to the burst of elastic fiber synthesis in the postpartum vagina. The finding that distention results in accelerated pelvic organ prolapse in Fbln5−/− animals, but not in WT, indicates that elastic fiber synthesis is crucial for recovery of the vaginal wall from distention-induced increases in vaginal protease activity. PMID:18635445

Accelerated reliability testing of highly aligned single-walled carbon nanotube networks subjected to DC electrical stressing.

PubMed

Strus, Mark C; Chiaramonti, Ann N; Kim, Young Lae; Jung, Yung Joon; Keller, Robert R

2011-07-01

We investigate the electrical reliability of nanoscale lines of highly aligned, networked, metallic/semiconducting single-walled carbon nanotubes (SWCNTs) fabricated through a template-based fluidic assembly process. We find that these SWCNT networks can withstand DC current densities larger than 10 MA cm(-2) for several hours and, in some cases, several days. We develop test methods that show that the degradation rate, failure predictability and total device lifetime can be linked to the initial resistance. Scanning electron and transmission electron microscopy suggest that fabrication variability plays a critical role in the rate of degradation, and we offer an empirical method of quickly determining the long-term performance of a network. We find that well-fabricated lines subject to constant electrical stress show a linear accumulation of damage reminiscent of electromigration in metallic interconnects, and we explore the underlying physical mechanisms that could cause such behavior.

Displacement of plasma protein and conduction velocity in rats under action of acceleration forces and hypokinesia

NASA Technical Reports Server (NTRS)

Baranski, S.; Edelwejn, Z.; Wojtkowiak, M.

1980-01-01

The permeability of capillary vessels was investigated in order to determine if acceleration alone or following prolonged hypokinesia would induce changes in the vascular wall leading to the penetration by l-albumins and/or proteins with larger molecules. In rats undergoing action of +5 Gz accelerations, no increase in vascular permeability, as tested with the use of (Cr-5k)-globulin, was demostrated. In rats immobilized for 4 weeks before centrifugation, rather weak migration of (Cr-51)-globulin from the vessels was observed. Immobilization resulted also in lowering of conduction velocity in the sciatic nerve.

Vacuum-surface flashover switch with cantilever conductors

DOEpatents

Caporaso, George J.; Sampayan, Stephen E.; Kirbie, Hugh C.

2001-01-01

A dielectric-wall linear accelerator is improved by a high-voltage, fast rise-time switch that includes a pair of electrodes between which are laminated alternating layers of isolated conductors and insulators. A high voltage is placed between the electrodes sufficient to stress the voltage breakdown of the insulator on command. A light trigger, such as a laser, is focused along at least one line along the edge surface of the laminated alternating layers of isolated conductors and insulators extending between the electrodes. The laser is energized to initiate a surface breakdown by a fluence of photons, thus causing the electrical switch to close very promptly. Such insulators and lasers are incorporated in a dielectric wall linear accelerator with Blumlein modules, and phasing is controlled by adjusting the length of fiber optic cables that carry the laser light to the insulator surface.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharp, D.J.; Panitz, J.K.G.; Mattox, D.M.

The erosion of materials by low energy ions is of concern in fusion reactors since high Z impurities in the plasma cause radiation cooling. Ion bombardment of the fusion reactor chamber walls arises from ions of fuel (D, T) material, gaseous impurities (O, C), and impurities from eroded components (Fe, Co, Ni, C, Mo, etc.) being accelerated across the wall sheath potential (0.1 to 1 keV). A Kaufman type ion source has been characterized for use with hydrogen, and subsequently used to determine the relative erosion rates of bulk Mo, C, Cu, coating of TiB/sub 2/, B/sub 4/C, Be, VBe/submore » 12/ and other materials. Ions of hydrogen (Z=1), argon (Z=18), and xenon (Z=54) at acceleration potentials of 250, 500, and 1000 V have been used to determine erosion yields.« less

Pulsed Electromagnetic Acceleration of Plasma: A Review

NASA Technical Reports Server (NTRS)

Thio, Y. C. Francis; Turchi, Peter J.; Markusic, Thomas E.; Cassibry, Jason T.; Sommer, James; Rodgers, Stephen L. (Technical Monitor)

2002-01-01

Much have been learned in the acceleration mechanisms involved in accelerating a plasma electromagnetically in the laboratory over the last 40 years since the early review by Winston Bostik of 1963, but the accumulated understanding is very much scattered throughout the literature. This literature extends back at least to the early sixties and includes Rosenbluth's snowplow model, discussions by Ralph Lovberg, Colgate's boundary-layer model of a current sheet, many papers from the activity at Columbia by Robert Gross and his colleagues, and the relevant, 1-D unsteady descriptions developed from the U. of Maryland theta-pinch studies. Recent progress on the understanding of the pulsed penetration of magnetic fields into collisionless or nearly collisionless plasmas are also be reviewed. Somewhat more recently, we have the two-dimensional, unsteady results in the collisional regime associated with so-called wall-instability in large radius pinch discharges and also in coaxial plasma guns (e.g., Plasma Flow Switch). Among other things, for example, we have the phenomenon of a high- density plasma discharge propagating in a cooaxial gun as an apparently straight sheet (vs paraboloid) because mass re-distribution (on a microsecond timescale) compensates for the 1/r- squared variation of magnetic pressure. We will attempt to collate some of this vast material and bring some coherence tc the development of the subject.

Accelerated killing of cancer cells using a multifunctional single-walled carbon nanotube-based system for targeted drug delivery in combination with photothermal therapy.

PubMed

Jeyamohan, Prashanti; Hasumura, Takashi; Nagaoka, Yutaka; Yoshida, Yasuhiko; Maekawa, Toru; Kumar, D Sakthi

2013-01-01

The photothermal effect of single-walled carbon nanotubes (SWCNTs) in combination with the anticancer drug doxorubicin (DOX) for targeting and accelerated destruction of breast cancer cells is demonstrated in this paper. A targeted drug-delivery system was developed for selective killing of breast cancer cells with polyethylene glycol biofunctionalized and DOX-loaded SWCNTs conjugated with folic acid. In our work, in vitro drug-release studies showed that the drug (DOX) binds at physiological pH (pH 7.4) and is released only at a lower pH, ie, lysosomal pH (pH 4.0), which is the characteristic pH of the tumor environment. A sustained release of DOX from the SWCNTs was observed for a period of 3 days. SWCNTs have strong optical absorbance in the near-infrared (NIR) region. In this special spectral window, biological systems are highly transparent. Our study reports that under laser irradiation at 800 nm, SWCNTs exhibited strong light-heat transfer characteristics. These optical properties of SWCNTs open the way for selective photothermal ablation in cancer therapy. It was also observed that internalization and uptake of folate-conjugated NTs into cancer cells was achieved by a receptor-mediated endocytosis mechanism. Results of the in vitro experiments show that laser was effective in destroying the cancer cells, while sparing the normal cells. When the above laser effect was combined with DOX-conjugated SWCNTs, we found enhanced and accelerated killing of breast cancer cells. Thus, this nanodrug-delivery system, consisting of laser, drug, and SWCNTs, looks to be a promising selective modality with high treatment efficacy and low side effects for cancer therapy.

R&D around a photoneutralizer-based NBI system (Siphore) in view of a DEMO Tokamak steady state fusion reactor

NASA Astrophysics Data System (ADS)

Simonin, A.; Achard, Jocelyn; Achkasov, K.; Bechu, S.; Baudouin, C.; Baulaigue, O.; Blondel, C.; Boeuf, J. P.; Bresteau, D.; Cartry, G.; Chaibi, W.; Drag, C.; de Esch, H. P. L.; Fiorucci, D.; Fubiani, G.; Furno, I.; Futtersack, R.; Garibaldi, P.; Gicquel, A.; Grand, C.; Guittienne, Ph.; Hagelaar, G.; Howling, A.; Jacquier, R.; Kirkpatrick, M. J.; Lemoine, D.; Lepetit, B.; Minea, T.; Odic, E.; Revel, A.; Soliman, B. A.; Teste, P.

2015-11-01

Since the signature of the ITER treaty in 2006, a new research programme targeting the emergence of a new generation of neutral beam (NB) system for the future fusion reactor (DEMO Tokamak) has been underway between several laboratories in Europe. The specifications required to operate a NB system on DEMO are very demanding: the system has to provide plasma heating, current drive and plasma control at a very high level of power (up to 150 MW) and energy (1 or 2 MeV), including high performances in term of wall-plug efficiency (η  >  60%), high availability and reliability. To this aim, a novel NB concept based on the photodetachment of the energetic negative ion beam is under study. The keystone of this new concept is the achievement of a photoneutralizer where a high power photon flux (~3 MW) generated within a Fabry-Perot cavity will overlap, cross and partially photodetach the intense negative ion beam accelerated at high energy (1 or 2 MeV). The aspect ratio of the beam-line (source, accelerator, etc) is specifically designed to maximize the overlap of the photon beam with the ion beam. It is shown that such a photoneutralized based NB system would have the capability to provide several tens of MW of D0 per beam line with a wall-plug efficiency higher than 60%. A feasibility study of the concept has been launched between different laboratories to address the different physics aspects, i.e. negative ion source, plasma modelling, ion accelerator simulation, photoneutralization and high voltage holding under vacuum. The paper describes the present status of the project and the main achievements of the developments in laboratories.

Compressed sensing for rapid late gadolinium enhanced imaging of the left atrium: A preliminary study.

PubMed

Kamesh Iyer, Srikant; Tasdizen, Tolga; Burgon, Nathan; Kholmovski, Eugene; Marrouche, Nassir; Adluru, Ganesh; DiBella, Edward

2016-09-01

Current late gadolinium enhancement (LGE) imaging of left atrial (LA) scar or fibrosis is relatively slow and requires 5-15min to acquire an undersampled (R=1.7) 3D navigated dataset. The GeneRalized Autocalibrating Partially Parallel Acquisitions (GRAPPA) based parallel imaging method is the current clinical standard for accelerating 3D LGE imaging of the LA and permits an acceleration factor ~R=1.7. Two compressed sensing (CS) methods have been developed to achieve higher acceleration factors: a patch based collaborative filtering technique tested with acceleration factor R~3, and a technique that uses a 3D radial stack-of-stars acquisition pattern (R~1.8) with a 3D total variation constraint. The long reconstruction time of these CS methods makes them unwieldy to use, especially the patch based collaborative filtering technique. In addition, the effect of CS techniques on the quantification of percentage of scar/fibrosis is not known. We sought to develop a practical compressed sensing method for imaging the LA at high acceleration factors. In order to develop a clinically viable method with short reconstruction time, a Split Bregman (SB) reconstruction method with 3D total variation (TV) constraints was developed and implemented. The method was tested on 8 atrial fibrillation patients (4 pre-ablation and 4 post-ablation datasets). Blur metric, normalized mean squared error and peak signal to noise ratio were used as metrics to analyze the quality of the reconstructed images, Quantification of the extent of LGE was performed on the undersampled images and compared with the fully sampled images. Quantification of scar from post-ablation datasets and quantification of fibrosis from pre-ablation datasets showed that acceleration factors up to R~3.5 gave good 3D LGE images of the LA wall, using a 3D TV constraint and constrained SB methods. This corresponds to reducing the scan time by half, compared to currently used GRAPPA methods. Reconstruction of 3D LGE images using the SB method was over 20 times faster than standard gradient descent methods. Copyright © 2016 Elsevier Inc. All rights reserved.

2 MeV linear accelerator for industrial applications

NASA Astrophysics Data System (ADS)

Smith, Richard R.; Farrell, Sherman R.

1997-02-01

RPC Industries has developed a high average power scanned electron beam linac system for medium energy industrial processing, such as in-line sterilization. The parameters are: electron energy 2 MeV; average beam current 5.0 mA; and scanned width 0.5 meters. The control system features data logging and a Man-Machine Interface system. The accelerator is vertically mounted, the system height above the floor is 3.4 m, and the footprint is 0.9×1.2 meter2. The typical processing cell inside dimensions are 3.0 m by 3.5 m by 4.2 m high with concrete side walls 0.5 m thick above ground level. The equal exit depth dose is 0.73 gm cm-2. Additional topics that will be reported are: throughput, measurements of dose vs depth, dose uniformity across the web, and beam power by calorimeter and magnetic deflection of the beam.

In tobacco BY-2 cells xyloglucan oligosaccharides alter the expression of genes involved in cell wall metabolism, signalling, stress responses, cell division and transcriptional control.

PubMed

González-Pérez, Lien; Perrotta, Lara; Acosta, Alexis; Orellana, Esteban; Spadafora, Natasha; Bruno, Leonardo; Bitonti, Beatrice M; Albani, Diego; Cabrera, Juan Carlos; Francis, Dennis; Rogers, Hilary J

2014-10-01

Xyloglucan oligosaccharides (XGOs) are breakdown products of XGs, the most abundant hemicelluloses of the primary cell walls of non-Poalean species. Treatment of cell cultures or whole plants with XGOs results in accelerated cell elongation and cell division, changes in primary root growth, and a stimulation of defence responses. They may therefore act as signalling molecules regulating plant growth and development. Previous work suggests an interaction with auxins and effects on cell wall loosening, however their mode of action is not fully understood. The effect of an XGO extract from tamarind (Tamarindus indica) on global gene expression was therefore investigated in tobacco BY-2 cells using microarrays. Over 500 genes were differentially regulated with similar numbers and functional classes of genes up- and down-regulated, indicating a complex interaction with the cellular machinery. Up-regulation of a putative XG endotransglycosylase/hydrolase-related (XTH) gene supports the mechanism of XGO action through cell wall loosening. Differential expression of defence-related genes supports a role for XGOs as elicitors. Changes in the expression of genes related to mitotic control and differentiation also support previous work showing that XGOs are mitotic inducers. XGOs also affected expression of several receptor-like kinase genes and transcription factors. Hence, XGOs have significant effects on expression of genes related to cell wall metabolism, signalling, stress responses, cell division and transcriptional control.

A Generalized Wall Function

NASA Technical Reports Server (NTRS)

Shih, Tsan-Hsing; Povinelli, Louis A.; Liu, Nan-Suey; Potapczuk, Mark G.; Lumley, J. L.

1999-01-01

The asymptotic solutions, described by Tennekes and Lumley (1972), for surface flows in a channel, pipe or boundary layer at large Reynolds numbers are revisited. These solutions can be extended to more complex flows such as the flows with various pressure gradients, zero wall stress and rough surfaces, etc. In computational fluid dynamics (CFD), these solutions can be used as the boundary conditions to bridge the near-wall region of turbulent flows so that there is no need to have the fine grids near the wall unless the near-wall flow structures are required to resolve. These solutions are referred to as the wall functions. Furthermore, a generalized and unified law of the wall which is valid for whole surface layer (including viscous sublayer, buffer layer and inertial sublayer) is analytically constructed. The generalized law of the wall shows that the effect of both adverse and favorable pressure gradients on the surface flow is very significant. Such as unified wall function will be useful not only in deriving analytic expressions for surface flow properties but also bringing a great convenience for CFD methods to place accurate boundary conditions at any location away from the wall. The extended wall functions introduced in this paper can be used for complex flows with acceleration, deceleration, separation, recirculation and rough surfaces.

A Study of Bubble and Slug Gas-Liquid Flow in a Microgravity Environment

NASA Technical Reports Server (NTRS)

McQuillen, J.

2000-01-01

The influence of gravity on the two-phase flow dynamics is obvious.As the gravity level is reduced,there is a new balance between inertial and interfacial forces, altering the behavior of the flow. In bubbly flow,the absence of drift velocity leads to spherical-shaped bubbles with a rectilinear trajectory.Slug flow is a succession of long bubbles and liquid slug carrying a few bubbles. There is no flow reversal in the thin liquid film as the long bubble and liquid slug pass over the film. Although the flow structure seems to be simpler than in normal gravity conditions,the models developed for the prediction of flow behavior in normal gravity and extended to reduced gravity flow are unable to predict the flow behavior correctly.An additional benefit of conducting studies in microgravity flows is that these studies aide the development of understanding for normal gravity flow behavior by removing the effects of buoyancy on the shape of the interface and density driven shear flows between the gas and the liquid phases. The proposal calls to study specifically the following: 1) The dynamics of isolated bubbles in microgravity liquid flows will be analyzed: Both the dynamics of spherical isolated bubbles and their dispersion by turbulence, their interaction with the pipe wall,the behavior of the bubbles in accelerated or decelerated flows,and the dynamics of isolated cylindrical bubbles, their deformation in accelerated/decelerated flows (in converging or diverging channels), and bubble/bubble interaction. Experiments will consist of the use of Particle Image Velocimetry (PIV) and Laser Doppler Velocimeters (LDV) to study single spherical bubble and single and two cylindrical bubble behavior with respect to their influence on the turbulence of the surrounding liquid and on the wall 2) The dynamics of bubbly and slug flow in microgravity will be analyzed especially for the role of the coalescence in the transition from bubbly to slug flow (effect of fluid properties and surfactant), to identify clusters that promote coalescence and transition the void fraction distribution in bubbly and slug flow,to measure the wall friction in bubbly flow. These experiments will consist of multiple bubbles type flows and will utilize hot wire and film anemometers to measure liquid velocity and wall shear stress respectively and double fiber optic probes to measure bubble size and velocity as a function of tube radius and axial location.

On thick domain walls in general relativity

NASA Technical Reports Server (NTRS)

Goetz, Guenter; Noetzold, Dirk

1989-01-01

Planar scalar field configurations in general relativity differ considerably from those in flat space. It is shown that static domain walls of finite thickness in curved space-time do not possess a reflection symmetry. At infinity, the space-time tends to the Taub vacuum on one side of the wall and to the Minkowski vacuum (Rindler space-time) on the other. Massive test particles are always accelerated towards the Minkowski side, i.e., domain walls are attractive on the Taub side, but repulsive on the Minkowski side (Taub-vacuum cleaner). It is also proved that the pressure in all directions is always negative. Finally, a brief comment is made concerning the possibility of infinite, i.e., bigger than horizon size, domain walls in our universe. All of the results are independent of the form of the potential V(phi) greater than or equal to 0 of the scalar field phi.

Slot-coupled CW standing wave accelerating cavity

DOEpatents

Wang, Shaoheng; Rimmer, Robert; Wang, Haipeng

2017-05-16

A slot-coupled CW standing wave multi-cell accelerating cavity. To achieve high efficiency graded beta acceleration, each cell in the multi-cell cavity may include different cell lengths. Alternatively, to achieve high efficiency with acceleration for particles with beta equal to 1, each cell in the multi-cell cavity may include the same cell design. Coupling between the cells is achieved with a plurality of axially aligned kidney-shaped slots on the wall between cells. The slot-coupling method makes the design very compact. The shape of the cell, including the slots and the cone, are optimized to maximize the power efficiency and minimize the peak power density on the surface. The slots are non-resonant, thereby enabling shorter slots and less power loss.

Biodegradation of Single-Walled Carbon Nanotubes in Macrophages through Respiratory Burst Modulation

PubMed Central

Hou, Jie; Wan, Bin; Yang, Yu; Ren, Xiao-Min; Guo, Liang-Hong; Liu, Jing-Fu

2016-01-01

The biodegradation of carbon nanotubes (CNTs) may be one of major determinants of the toxic outcomes in exposed individuals. In this study, we employed a macrophage/monocyte model, Raw264.7, to investigate the feasibility of regulating the biodegradation of three types of single-walled carbon nanotubes (SWCNTs) (pristine, ox-, and OH-SWCNTs) by respiratory burst modulation. An artificial fluid mimicking the enzymatic reactions of respiratory burst was constituted to reveal the role of respiratory burst played in SWCNT biodegradation. The biodegradation of SWCNTs were characterized by Raman, ultraviolet-visible-near-infrared spectroscopy, and transmission electron microscopy. Our results showed significantly accelerated biodegradation of ox-SWCNTs and OH-SWCNTs in macrophages activated by phorbol myristate acetate (PMA), which could be prevented by N-acetyl-l-cysteine (NAC), whereas p-SWCNTs were resistant to biodegradation. Similar tendencies were observed by using the in vitro enzymatic system, and the degradation rates of these SWCNTs are in the order of OH-SWCNTs > ox-SWCNTs >> p-SWCNTs, suggesting a pivotal role of respiratory burst in accelerating the biodegradation of SWCNTs and that defect sites on SWCNTs might be a prerequisite for the biodegradation to occur. Our findings might provide invaluable clues on the development of intervention measurements for relieving the side effects of SWCNTs and would help to design safer SWCNT products with higher biodegradability and less toxicity. PMID:27011169

Numerical validation of axial plasma momentum lost to a lateral wall induced by neutral depletion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Takao, Yoshinori, E-mail: takao@ynu.ac.jp; Takahashi, Kazunori

2015-11-15

Momentum imparted to a lateral wall of a compact inductively coupled plasma thruster is numerically investigated for argon and xenon gases by a particle-in-cell simulation with Monte Carlo collisions (PIC-MCC). Axial plasma momentum lost to a lateral wall is clearly shown when axial depletion of the neutrals is enhanced, which is in qualitative agreement with the result in a recent experiment using a helicon plasma source [Takahashi et al., Phys. Rev. Lett. 114, 195001 (2015)]. The PIC-MCC calculations demonstrate that the neutral depletion causes an axially asymmetric profile of the plasma density and potential, leading to axial ion acceleration andmore » the non-negligible net axial force exerted to the lateral wall in the opposite direction of the thrust.« less

Flow-accelerated corrosion 2016 international conference

NASA Astrophysics Data System (ADS)

Tomarov, G. V.; Shipkov, A. A.

2017-05-01

The paper discusses materials and results of the most representative world forum on the problems of flow-accelerated metal corrosion in power engineering—Flow-Accelerated Corrosion (FAC) 2016, the international conference, which was held in Lille (France) from May 23 through May 27, 2016, sponsored by EdF-DTG with the support of the International Atomic Energy Agency (IAEA) and the World Association of Nuclear Operators (WANO). The information on major themes of reports and materials of the exhibition arranged within the framework of the congress is presented. The statistics on operation time and intensity of FAC wall thinning of NPP pipelines and equipment in the world is set out. The paper describes typical examples of flow-accelerated corrosion damage of condensate-feed and wet-steam pipeline components of nuclear and thermal power plants that caused forced shutdowns or accidents. The importance of research projects on the problem of flow-accelerated metal corrosion of nuclear power units coordinated by the IAEA with the participation of leading experts in this field from around the world is considered. The reports presented at the conference considered issues of implementation of an FAC mechanism in single- and two-phase flows, the impact of hydrodynamic and water-chemical factors, the chemical composition of the metal, and other parameters on the intensity and location of FAC wall thinning localized areas in pipeline components and power equipment. Features and patterns of local and general FAC leading to local metal thinning and contamination of the working environment with ferriferous compounds are considered. Main trends of modern practices preventing FAC wear of NPP pipelines and equipment are defined. An increasing role of computer codes for the assessment and prediction of FAC rate, as well as software systems of support of the NPP personnel for the inspection planning and prevention of FAC wall thinning of equipment operating in singleand two-phase flows, is accepted. Different lines of attack on the problem of FAC of pipelines and equipment components of existing and future nuclear power units are reviewed. Promising methods of nondestructive inspection of pipelines and equipment are presented.

Ubiquitous Low-Cost Functionalized Multi-Walled Carbon Nanotube Sensors for Distributed Methane Leak Detection

DOE PAGES

Humayun, Md Tanim; Divan, Ralu; Stan, Liliana; ...

2016-06-16

This paper presents a highly sensitive, energy efficient and low-cost distributed methane (CH 4) sensor system (DMSS) for continuous monitoring, detection, and localization of CH 4 leaks in natural gas infrastructure, such as transmission and distribution pipelines, wells, and production pads. The CH 4 sensing element, a key component of the DMSS, consists of a metal oxide nanocrystal (MONC) functionalized multi-walled carbon nanotube (MWCNT) mesh which, in comparison to existing literature, shows stronger relative resistance change while interacting with lower parts per million (ppm) concentration of CH 4. A Gaussian plume triangulation algorithm has been developed for the DMSS. Givenmore » a geometric model of the surrounding environment the algorithm can precisely detect and localize a CH 4 leak as well as estimate its mass emission rate. A UV-based surface recovery technique making the sensor recover 10 times faster than the reported ones is presented for the DMSS. In conclusion, a control algorithm based on the UV-accelerated recovery is developed which facilitates faster leak detection.« less

Response of Olive View Hospital to Northridge and Whittier earthquakes

USGS Publications Warehouse

Celebi, M.

1997-01-01

The purpose of this paper is to study the response of the conventionally designed new Olive View Medical Center (OVMC) building at 16 km from the epicenter of the January 17, 1994 Northridge, California earthquake (Ms = 6.8). OVMC is on an alluvial deposit. The building was subjected to design level peak accelerations during the earthquake and suffered only limited structural and nonstructural damage. The recorded motions at different levels of the OVMC building as well as its associated free-field sites are analyzed using spectral analyses and system identification techniques. The new OVMC building was conservatively designed in 1976 with very high lateral load resisting capability - particularly as a reaction to the detrimental fate of the original Olive View Hospital that was heavily damaged during the 1971 San Fernando earthquake. The original hospital building was later razed. The replacement structure, the new cross-shaped OVMC building, experienced peak acceleration of 2.31g at the roof while its peak ground floor acceleration was 0.82g. The free-field peak acceleration was 0.91g. The lateral load resisting system of the OVMC building consists of concrete shear walls in the lower two stories and steel shear walls at the perimeter of the upper four stories. Spectral analysis shows that this stiff structure was not affected by the long duration pulses of the motions recorded at this site.

Theory of vibratory mobilization and break-up of non-wetting fluids entrapped in pore constrictions

NASA Astrophysics Data System (ADS)

Beresnev, I.; Li, W.; Vigil, D.

2006-12-01

Quantitative dynamics of a non-wetting (e. g., NAPL) ganglion entrapped in a pore constriction and subjected to vibrations can be approximated by the equation of motion of an oscillator moving under the effect of the external pressure gradient, inertial oscillatory force, and restoring capillary force. The solution of the equation provides the conditions under which the droplet experiences forced oscillations without being mobilized or is liberated upon the acceleration of the wall exceeding an "unplugging" threshold. This solution provides a quantitative tool for the estimation of the parameters of vibratory fields needed to liberate entrapped non-wetting fluids. For typical pore sizes encountered in reservoirs and aquifers, wall accelerations must exceed at least several m/sec2 and even higher levels to mobilize the droplets of NAPL; however, in the populations of ganglia entrapped in natural porous environments, many may reside very near their mobilization thresholds and may be mobilized by extremely low accelerations as well. For given acceleration, lower seismic frequencies are more efficient. The ganglia may also break up into smaller pieces when passing through pore constrictions. The snap-off is governed by the geometry only; for constrictions with sinusoidal profile (spatial wavelength of L and maximum and minimum radii of rmax and rmin, the break-up occurs if L > 2π(rmin rmax)1/2. Computational fluid dynamics shows the details of the break-up process.

Study of Corona Discharge on 160 KeV, 10 mA Electron Accelerator Facility Using FEM

NASA Astrophysics Data System (ADS)

Ghazali, Abu Bakar Mhd; Sobri, Rokiah Mohd

2008-05-01

This paper describes a method to verify the overall design of our electron accelerator. It is free from corona or spark discharge phenomenon. This locally designed electron accelerator facility is located at Nuclear Malaysia Complex, Bangi, Selangor. In this study, we describe the geometry of the pressure vessel filled with SF6 gas at 2 atm to enclose the high voltage area of the accelerating tube. The Poisson's equation is used to calculate the contours of the electric field that is created between the cathode of -160 kV maximum and the wall of the vessel. The nearest sharp edge between the cathode and the pressure wall is 163 mm apart. The calculation is based on finite element method (FEM) for electrostatic charges in order to obtain an electric field contour in two-dimensional plane. We found that the surface charge density of the cathode is 1.1×10-5 C/m2 for the corona glowing seen at -90 kV. Moreover, the highest electric field near to (about 5 mm from) the sharp edge is about 2.7 MV/m, which is less than the dielectric strength of SF6 gas, i.e. 6 MV/m and therefore, it proved that our design of the pressure vessel is save from corona or spark discharges.

Successful experiments on an external MHD Accelerator: wall confinement of the plasma, annihilation of the electrothermal instability by magnetic gradient inversion, creation of a stable spiral current pattern

NASA Astrophysics Data System (ADS)

Petit, Jean-Pierre; Dore, Jean-Christophe

2013-09-01

MHD propulsion has been extensively studied since the fifties. To shift from propulsion to an MHD Aerodyne, one only needs to accelerate the air externally, along its outer skin, using Lorentz forces. We present a set of successful experiments, obtained around a model, placed in low density air. We successfully dealt with various problems: wall confinement of two-temperature plasma obtained by inversion of the magnetic pressure gradient, annihilation of the Velikhov electrothermal instability by magnetic confinement of the streamers, establishment of a stable spiral distribution of the current, obtained by an original method. Another direction of research is devoted to the study of an MHD-controlled inlet which, coupled with a turbofan engine and implying an MHD-bypass system, would extend the flight domain to hypersonic conditions. Research manager

HEAT TRANSFER METHOD

DOEpatents

Gambill, W.R.; Greene, N.D.

1960-08-30

A method is given for increasing burn-out heat fluxes under nucleate boiling conditions in heat exchanger tubes without incurring an increase in pumping power requirements. This increase is achieved by utilizing a spinning flow having a rotational velocity sufficient to produce a centrifugal acceleration of at least 10,000 g at the tube wall. At this acceleration the heat-transfer rate at burn out is nearly twice the rate which can be achieved in a similar tube utilizing axial flow at the same pumping power. At higher accelerations the improvement over axial flow is greater, and heat fluxes in excess of 50 x 10/sup 6/ Btu/hr/sq ft can be achieved.

Taking Down a Giant: 699 Tons of SLAC’s Accelerator Removed for Upgrade

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2017-01-31

For the first time in more than 50 years, a door opened at the western end of the historic linear accelerator at the Department of Energy’s SLAC National Accelerator Laboratory casts light on four empty walls stretching as far as the eye can see. This end of the linac – a full kilometer of it – has been stripped of all its equipment both above and below ground. Over the next two years it will be re-equipped with new technology to power another wonder of modern science: an X-ray laser that will fire a million pulses per second.

The isolation limits of stochastic vibration

NASA Technical Reports Server (NTRS)

Knopse, C. R.; Allaire, P. E.

1993-01-01

The vibration isolation problem is formulated as a 1D kinematic problem. The geometry of the stochastic wall trajectories arising from the stroke constraint is defined in terms of their significant extrema. An optimal control solution for the minimum acceleration return path determines a lower bound on platform mean square acceleration. This bound is expressed in terms of the probability density function on the significant maxima and the conditional fourth moment of the first passage time inverse. The first of these is found analytically while the second is found using a Monte Carlo simulation. The rms acceleration lower bound as a function of available space is then determined through numerical quadrature.

Method of and apparatus for accelerating a projectile

DOEpatents

Goldstein, Yeshayahu S. A.; Tidman, Derek A.

1986-01-01

A projectile is accelerated along a confined path by supplying a pulsed high pressure, high velocity plasma jet to the rear of the projectile as the projectile traverses the path. The jet enters the confined path at a non-zero angle relative to the projectile path. The pulse is derived from a dielectric capillary tube having an interior wall from which plasma forming material is ablated in response to a discharge voltage. The projectile can be accelerated in response to the kinetic energy in the plasma jet or in response to a pressure increase of gases in the confined path resulting from the heat added to the gases by the plasma.

Numerical Study of Controlling Jet Flow and Noise using Pores on Nozzle Inner Wall

NASA Astrophysics Data System (ADS)

Lin, Jian; Shi, Zhixiao; Lai, Huanxin

2018-04-01

In this paper, the feasibility of controlling the subsonic jet flow and its noise using pores of blind holes added on the nozzle inner wall is explored numerically. These pores are intended to introduce disturbances to the shear layer so as to change the flow mixing. This passive strategy has not been attempted so far. A convergent nozzle with a cylindrical extension is selected as the baseline case. Three nozzles with pores on the inner wall are set up. Validations of the numerical settings are carried out, then the compressible turbulent jets at the exit Mach number M j = 0.6 in the four nozzles are calculated by large eddy simulations (LES), while the radiated sounds are predicted by the FW-H acoustic analogy. The results show that the blind holes have produced some effects on weakening the turbulence intensity in the shear layer. Comparison reveals that both temporal and spatial correlations of the turbulent fluctuations in the modified cases are suppressed to some extent. Meanwhile, the porous nozzles are shown to suppress the pairing of vortices and enhance the flow mixing, and therefore, the development of shear layer and the fragmentation of large scale vortices are accelerated.

A study of transient flow turbulence generation during flame/wall interactions in explosions

NASA Astrophysics Data System (ADS)

Hargrave, G. K.; Jarvis, S.; Williams, T. C.

2002-07-01

Experimental data are presented for the turbulent velocity field generated during flame/solid wall interactions in explosions. The presence of turbulence in a flammable gas mixture can wrinkle a flame front, increasing the flame surface area and enhancing the burning rate. In congested process plant, any flame propagating through an accidental release of flammable mixture will encounter obstructions in the form of walls, pipe-work or storage vessels. The interaction between the gas movement and the obstacle creates turbulence by vortex shedding and local wake/recirculation, whereby the flame can be wrapped in on itself, increasing the surface area available for combustion. Particle image velocimetry (PIV) was used to characterize the turbulent flow field in the wake of the obstacles placed in the path of propagating flames. This allowed the quantification of the interaction of the propagating flame and the generated turbulent flow field. Due to the accelerating nature of the explosion flow field, the wake flows develop `transient' turbulent fields and PIV provided data to define the spatial and temporal variation of the velocity field ahead of the propagating flame, providing an understanding of the direct interaction between flow and flame.

Monitoring of corrosion damage using high-frequency guided ultrasonic waves

NASA Astrophysics Data System (ADS)

Chew, D.; Fromme, P.

2014-03-01

Due to adverse environmental conditions corrosion can develop during the life cycle of industrial structures, e.g., offshore oil platforms, ships, and desalination plants. Both pitting corrosion and generalized corrosion leading to wall thickness loss can cause the degradation of the integrity and load bearing capacity of the structure. Structural health monitoring of corrosion damage in difficult to access areas can in principle be achieved using high frequency guided waves propagating along the structure from accessible areas. Using standard ultrasonic transducers with single sided access to the structure, high frequency guided wave modes were generated that penetrate through the complete thickness of the structure. Wall thickness reduction was induced using accelerated corrosion in a salt water bath. The corrosion damage was monitored based on the effect on the wave propagation and interference of the different modes. The change in the wave interference was quantified based on an analysis in the frequency domain (Fourier transform) and was found to match well with theoretical predictions for the wall thickness loss. High frequency guided waves have the potential for corrosion damage monitoring at critical and difficult to access locations from a stand-off distance.

Monitoring of corrosion damage using high-frequency guided ultrasonic waves

NASA Astrophysics Data System (ADS)

Chew, D.; Fromme, P.

2015-03-01

Due to adverse environmental conditions corrosion can develop during the life cycle of industrial structures, e.g., offshore oil platforms, ships, and desalination plants. Both pitting corrosion and generalized corrosion leading to wall thickness loss can cause the degradation of the integrity and load bearing capacity of the structure. Structural health monitoring of corrosion damage in difficult to access areas can in principle be achieved using high frequency guided waves propagating along the structure from accessible areas. Using standard ultrasonic transducers with single sided access to the structure, high frequency guided wave modes were generated that penetrate through the complete thickness of the structure. Wall thickness reduction was induced using accelerated corrosion in a salt water bath. The corrosion damage was monitored based on the effect on the wave propagation and interference of the different modes. The change in the wave interference was quantified based on an analysis in the frequency domain (Fourier transform) and was found to match well with theoretical predictions for the wall thickness loss. High frequency guided waves have the potential for corrosion damage monitoring at critical and difficult to access locations from a stand-off distance.

Ultrasonic Wall Thickness Monitoring at High Temperatures (>500 °C)

NASA Astrophysics Data System (ADS)

Cegla, F. B.; Allin, J.; Davies, J. O.; Collins, P.; Cawley, P.

2011-06-01

Corrosion and erosion shorten the life of components that are used in the petrochemical industry. In order to mitigate the safety and financial risks posed by the degradation mechanisms, plant operators monitor wall thicknesses at regular inspection intervals. In high temperature locations inspections have to be carried out at plant shut downs because conventional ultrasonic sensors cannot withstand the high operating temperatures. The authors have developed a waveguide based high temperature thickness gauge for monitoring of wall thicknesses in high temperature areas. The waveguide allows the use of conventional transduction systems (max temp. 60 °C) at one end and guides ultrasonic waves into the high temperature region where the inspection is to be carried out. Slender stainless steel waveguides allow a temperature drop of ˜500-600 °C per 200 mm length to be sustained simply by natural convection cooling. This paper describes the technical challenges that had to be overcome (dispersion and source/receiver characteristics) in order to implement this "acoustic cable". A range of experimental results of thickness measurements on components of different thickness, and furnace tests at different temperatures are presented. An accelerated corrosion test that demonstrates the effectiveness of the monitoring for corrosion is also presented.

Radiological Protection Studies for NGLS XTOD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xiao, Shanjie; Santana-Leitner, Mario; Rokni, Sayed

The X-ray transport, optics and diagnostic system (XTOD) starts from the end of bending magnets sending electrons to the main dump and ends at the end wall separating the accelerator tunnel from the user experimental hall (hereafter referred as EH wall), as shown in Figure 1. Figure 1.a shows the general schematic and Figure 1.b shows the initial layout with possible shielding components. This document summarizes the extensive studies on the shielding and collimator system design necessary to meet the radiation protection requirements.

Knudsen paradox in granular gases and the roles of thermal and athermal walls

NASA Astrophysics Data System (ADS)

Gupta, Ronak; Alam, Meheboob

2017-11-01

The well-known `Knudsen-paradox' (which refers to the decrease of the mass-flow rate of a gas with increasing Knudsen number Kn , reaching a minimum at Kn O(1) and increasing logarithmically with Kn as Kn -> ∞) is revisited using direct simulation Monte Carlo (DSMC) method. It is shown that the `Knudsen-paradox' survives in the acceleration-driven Poiseuille flow of a granular gas in contact with thermal-walls. This result is in contradiction with recent molecular dynamics simulations (Alam et al., J. Fluid Mech., vol. 782, 2015, pp. 99-126) that revealed the absence of the Knudsen-minimum in granular Poiseuille flow. The above conundrum is resolved by distinguishing between `thermal' and `athermal' walls, and it is shown that, for both molecular and granular gases, the momentum-transfer to athermal-walls is much lower than that to thermal-walls which is directly responsible for the ``anomalous'' flow-rate-variation with Kn . In the continuum limit of Kn -> 0 , the athermal walls are found to be closely related to `non-flux/adiabatic' walls. The underlying mechanistic arguments lead to Maxwell's slip-boundary condition and a possible characterization of athermal walls in terms of an effective specularity coefficient is discussed.

Enhancement of convective heat transfer in internal flows using an electrically-induced corona jet

NASA Astrophysics Data System (ADS)

Baghaei Lakeh, Reza

The enhancement of heat transfer by active and passive methods has been the subject of many academic and industrial research studies. Internal flows play a major role in many applications and different methods have been utilized to augment the heat transfer to internal flows. Secondary flows consume part of the kinetic energy of the flow and disturb the boundary layer. Inducing secondary flows is known as mechanism for heat transfer enhancement. Secondary flows may be generated by corona discharge and ion-driven flows. When a high electric potential is applied to a conductor, a high electric field will be generated. The high electric field may exceed the partial break-down of the neutral molecules of surrounding gas (air) and generate a low-temperature plasma in the vicinity of the conductor. The generated plasma acts as a source of ions that accelerate under the influence of the electric field and escape beyond the plasma region and move toward the grounded electrode. The accelerating ions collide with neutral particles of the surrounding gas and impose a dragging effect which is interpreted as a body-force to the air particles. The shape and configuration of the emitting and receiving electrodes has a significant impact on the distribution of the electric body-force and the resulting electrically-induced flow field. It turned out that the certain configurations of longitudinal electrodes may cause a jet-like secondary flow field on the cross section of the flow passage in internal flows. The impingement effect of the corona jet on the walls of the channel disturbs the boundary layer, enhances the convective heat transfer, and generates targeted cooling along the centerline of the jet. The results of the current study show that the concentric configuration of a suspended wire-electrode in a circular tube leads to a hydrostatic condition and do not develop any electrically-induced secondary flow; however, the eccentric wire-electrode configuration generates a corona jet along the eccentricity direction. The generated corona jet exhibits interesting specifications similar to conventional inertia-driven air jets which are among common techniques for cooling and heat transfer enhancement. On the other hand, wall-mounted flat electrode pairs along the parallel walls of a rectangular mini-channel develop a similar jet-like flow pattern. The impingement of the corona jet to the receiving wall causes excessive heat transfer enhancement and cooling effect. The flat electrode pairs were also utilized to study the effect of corona discharge on the heat transfer specifications of the internal flow between parallel plates in fully-developed condition. It turned out that the electrically-induced secondary flow along with a pressure-driven main flow generates a swirling effect which can enhance the heat transfer significantly in fully-developed condition.

Potential dangers of accelerant use in arson.

PubMed

Heath, Karen; Kobus, Hilton; Byard, Roger W

2011-02-01

Accelerant-enhanced combustion often characterizes a fire that has been deliberately set to disguise a murder scene or to destroy property for insurance purposes. The intensity and rapidity of spread of fires where accelerants have been used are often underestimated by perpetrators who may sustain heat-related injuries. The case of a 49-year-old male who was using gasoline (petrol) as an accelerant is reported to demonstrate another danger of this type of activity. After ignition, an explosion occurred that destroyed the building and caused the death of the victim who was crushed beneath a rear wall of the commercial premises. Gasoline vapour/air mixtures are extremely volatile and may cause significant explosions if exposed to flame. Given the potential danger of explosion, arsonists using accelerants do so at significant risk to themselves and to others in the vicinity. Copyright © 2011 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

Basic and applied studies of the ram accelerator as a hypervelocity projectile launcher

NASA Astrophysics Data System (ADS)

Bruckner, Adam P.; Knowlen, Carl

1993-12-01

The potential of using ram accelerator technology for an impulsive launcher of autonomously guided interceptors, such as the LEAP, has been studied during this contract period. In addition, fundamental investigations on some of the engineering issues which must be addressed for enabling ram accelerator propulsive modes to operate at 4 km/sec have been undertaken. An experimental investigation of the gas dynamic limits of ram accelerator operation has demonstrated the existence of two distinct limiting mechanisms that must be accounted for when designing projectiles for these launchers. Other experiments were conducted to make detailed pressure measurements of the flow fields at the tube walls to study the effects of projectile canting. Results from this LEAP launcher study and the experimental investigations indicate that the ram accelerator technology is well suited for applications as a transportable launcher capable of meeting the needs of theater ballistic missile defense missions.

Towards Reduced Wall Effect Hall Plasma Accelerators

DTIC Science & Technology

2007-07-01

Unpublished Conference Presentations E. Fernandez, N. Borelli , M. Cappelli, N. Gascon, "Investigation of Fluctuation-Induced Electron Transport in Hall...International Electric Propulsion Conference, Princeton University, October 31 November 4, 2005. 38. E. Fernandez, N. Borelli , M. Cappelli, N. Gascon

Characterization of the radiation environment at the UNLV accelerator facility during operation of the Varian M6 linac

NASA Astrophysics Data System (ADS)

Hodges, M.; Barzilov, A.; Chen, Y.; Lowe, D.

2016-10-01

The bremsstrahlung photon flux from the UNLV particle accelerator (Varian M6 model) was determined using MCNP5 code for 3 MeV and 6 MeV incident electrons. Human biological equivalent dose rates due to accelerator operation were evaluated using the photon flux with the flux-to-dose conversion factors. Dose rates were computed for the accelerator facility for M6 linac use under different operating conditions. The results showed that the use of collimators and linac internal shielding significantly reduced the dose rates throughout the facility. It was shown that the walls of the facility, in addition to the earthen berm enveloping the building, provide equivalent shielding to reduce dose rates outside to below the 2 mrem/h limit.

3-D simulation of hanging wall effect at dam site

NASA Astrophysics Data System (ADS)

Zhang, L.; Xu, Y.

2017-12-01

Hanging wall effect is one of the near fault effects. This paper focuses on the difference of the ground motions on the hanging wall side between the footwall side of the fault at dam site considering the key factors, such as actual topography, the rupture process. For this purpose, 3-D ground motions are numerically simulated by the spectrum element method (SEM), which takes into account the physical mechanism of generation and propagation of seismic waves. With the SEM model of 548 million DOFs, excitation and propagation of seismic waves are simulated to compare the difference between the ground motion on the hanging wall side and that on the footwall side. Take Dagangshan region located in China as an example, several seismogenic finite faults with different dip angle are simulated to investigate the hanging wall effect. Furthermore, by comparing the ground motions of the receiving points, the influence of several factors on hanging wall effect is investigated, such as the dip of the fault and the fault type (strike slip fault or dip-slip fault). The peak acceleration on the hanging wall side is obviously larger than those on the footwall side, which numerically evidences the hanging wall effect. Besides, the simulation shows that only when the dip is less than 70° does the hanging wall effect deserve attention.

Cell Wall Assembly and Intracellular Trafficking in Plant Cells Are Directly Affected by Changes in the Magnitude of Gravitational Acceleration

PubMed Central

Chebli, Youssef; Pujol, Lauranne; Shojaeifard, Anahid; Brouwer, Iman; van Loon, Jack J. W. A.; Geitmann, Anja

2013-01-01

Plants are able to sense the magnitude and direction of gravity. This capacity is thought to reside in selected cell types within the plant body that are equipped with specialized organelles called statoliths. However, most plant cells do not possess statoliths, yet they respond to changes in gravitational acceleration. To understand the effect of gravity on the metabolism and cellular functioning of non-specialized plant cells, we investigated a rapidly growing plant cell devoid of known statoliths and without gravitropic behavior, the pollen tube. The effects of hyper-gravity and omnidirectional exposure to gravity on intracellular trafficking and on cell wall assembly were assessed in Camellia pollen tubes, a model system with highly reproducible growth behavior in vitro. Using an epi-fluorescence microscope mounted on the Large Diameter Centrifuge at the European Space Agency, we were able to demonstrate that vesicular trafficking is reduced under hyper-gravity conditions. Immuno-cytochemistry confirmed that both in hyper and omnidirectional gravity conditions, the characteristic spatial profiles of cellulose and callose distribution in the pollen tube wall were altered, in accordance with a dose-dependent effect on pollen tube diameter. Our findings suggest that in response to gravity induced stress, the pollen tube responds by modifying cell wall assembly to compensate for the altered mechanical load. The effect was reversible within few minutes demonstrating that the pollen tube is able to quickly adapt to changing stress conditions. PMID:23516452

Dynamic estimation of three-dimensional cerebrovascular deformation from rotational angiography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang Chong; Villa-Uriol, Maria-Cruz; De Craene, Mathieu

2011-03-15

Purpose: The objective of this study is to investigate the feasibility of detecting and quantifying 3D cerebrovascular wall motion from a single 3D rotational x-ray angiography (3DRA) acquisition within a clinically acceptable time and computing from the estimated motion field for the further biomechanical modeling of the cerebrovascular wall. Methods: The whole motion cycle of the cerebral vasculature is modeled using a 4D B-spline transformation, which is estimated from a 4D to 2D+t image registration framework. The registration is performed by optimizing a single similarity metric between the entire 2D+t measured projection sequence and the corresponding forward projections of themore » deformed volume at their exact time instants. The joint use of two acceleration strategies, together with their implementation on graphics processing units, is also proposed so as to reach computation times close to clinical requirements. For further characterizing vessel wall properties, an approximation of the wall thickness changes is obtained through a strain calculation. Results: Evaluation on in silico and in vitro pulsating phantom aneurysms demonstrated an accurate estimation of wall motion curves. In general, the error was below 10% of the maximum pulsation, even in the situation when substantial inhomogeneous intensity pattern was present. Experiments on in vivo data provided realistic aneurysm and vessel wall motion estimates, whereas in regions where motion was neither visible nor anatomically possible, no motion was detected. The use of the acceleration strategies enabled completing the estimation process for one entire cycle in 5-10 min without degrading the overall performance. The strain map extracted from our motion estimation provided a realistic deformation measure of the vessel wall. Conclusions: The authors' technique has demonstrated that it can provide accurate and robust 4D estimates of cerebrovascular wall motion within a clinically acceptable time, although it has to be applied to a larger patient population prior to possible wide application to routine endovascular procedures. In particular, for the first time, this feasibility study has shown that in vivo cerebrovascular motion can be obtained intraprocedurally from a 3DRA acquisition. Results have also shown the potential of performing strain analysis using this imaging modality, thus making possible for the future modeling of biomechanical properties of the vascular wall.« less

Slow waves in microchannel metal waveguides and application to particle acceleration

NASA Astrophysics Data System (ADS)

Steinhauer, L. C.; Kimura, W. D.

2003-06-01

Conventional metal-wall waveguides support waveguide modes with phase velocities exceeding the speed of light. However, for infrared frequencies and guide dimensions of a fraction of a millimeter, one of the waveguide modes can have a phase velocity equal to or less than the speed of light. Such a metal microchannel then acts as a slow-wave structure. Furthermore, if it is a transverse magnetic mode, the electric field has a component along the direction of propagation. Therefore, a strong exchange of energy can occur between a beam of charged particles and this slow-waveguide mode. Moreover, the energy exchange can be sustained over a distance limited only by the natural damping of the wave. This makes the microchannel metal waveguide an attractive possibility for high-gradient electron laser acceleration because the wave can be directly energized by a long-wavelength laser. Indeed the frequency of CO2 lasers lies at a fortuitous wavelength that produces a strong laser-particle interaction in a channel of reasonable macroscopic size (e.g., ˜0.6 mm). The dispersion properties including phase velocity and damping for the slow wave are developed. The performance and other issues related to laser accelerator applications are discussed.

Developing field emission electron sources based on ultrananocrystalline diamond for accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baryshev, Sergey V.; Jing, Chunguang; Qiu, Jiaqi

Radiofrequency (RF) electron guns work by establishing an RF electromagnetic field inside a cavity having conducting walls. Electrons from a cathode are generated in the injector and immediately become accelerated by the RF electric field, and exit the gun as a series of electron bunches. Finding simple solutions for electron injection is a long standing problem. While energies of 30-50 MeV are achievable in linear accelerators (linacs), finding an electron source able to survive under MW electric loads and provide an average current of 1-10 mA is important. Meeting these requirements would open various linac applications for industry. The naturalmore » way to simplify and integrate RF injector architectures with the electron source would be to place the source directly into the RF cavity with no need for additional heaters/lasers. Euclid TechLabs in collaboration with Argonne National Lab are prototyping a family of highly effective field emission electron sources based on a nitrogen-incorporated ultrananocrystalline diamond ((N)UNCD) platform. Determined metrics suggest that our emitters are emissive enough to meet requirements for magnetized cooling at electron-ion colliders, linac-based radioisotope production and X-ray sterilization, and others.« less

Properties of the electron cloud in a high-energy positron and electron storage ring

DOE PAGES

Harkay, K. C.; Rosenberg, R. A.

2003-03-20

Low-energy, background electrons are ubiquitous in high-energy particle accelerators. Under certain conditions, interactions between this electron cloud and the high-energy beam can give rise to numerous effects that can seriously degrade the accelerator performance. These effects range from vacuum degradation to collective beam instabilities and emittance blowup. Although electron-cloud effects were first observed two decades ago in a few proton storage rings, they have in recent years been widely observed and intensely studied in positron and proton rings. Electron-cloud diagnostics developed at the Advanced Photon Source enabled for the first time detailed, direct characterization of the electron-cloud properties in amore » positron and electron storage ring. From in situ measurements of the electron flux and energy distribution at the vacuum chamber wall, electron-cloud production mechanisms and details of the beam-cloud interaction can be inferred. A significant longitudinal variation of the electron cloud is also observed, due primarily to geometrical details of the vacuum chamber. Furthermore, such experimental data can be used to provide realistic limits on key input parameters in modeling efforts, leading ultimately to greater confidence in predicting electron-cloud effects in future accelerators.« less

Computational Fluid Dynamic simulations of pipe elbow flow.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Homicz, Gregory Francis

2004-08-01

One problem facing today's nuclear power industry is flow-accelerated corrosion and erosion in pipe elbows. The Korean Atomic Energy Research Institute (KAERI) is performing experiments in their Flow-Accelerated Corrosion (FAC) test loop to better characterize these phenomena, and develop advanced sensor technologies for the condition monitoring of critical elbows on a continuous basis. In parallel with these experiments, Sandia National Laboratories is performing Computational Fluid Dynamic (CFD) simulations of the flow in one elbow of the FAC test loop. The simulations are being performed using the FLUENT commercial software developed and marketed by Fluent, Inc. The model geometry and meshmore » were created using the GAMBIT software, also from Fluent, Inc. This report documents the results of the simulations that have been made to date; baseline results employing the RNG k-e turbulence model are presented. The predicted value for the diametrical pressure coefficient is in reasonably good agreement with published correlations. Plots of the velocities, pressure field, wall shear stress, and turbulent kinetic energy adjacent to the wall are shown within the elbow section. Somewhat to our surprise, these indicate that the maximum values of both wall shear stress and turbulent kinetic energy occur near the elbow entrance, on the inner radius of the bend. Additional simulations were performed for the same conditions, but with the RNG k-e model replaced by either the standard k-{var_epsilon}, or the realizable k-{var_epsilon} turbulence model. The predictions using the standard k-{var_epsilon} model are quite similar to those obtained in the baseline simulation. However, with the realizable k-{var_epsilon} model, more significant differences are evident. The maximums in both wall shear stress and turbulent kinetic energy now appear on the outer radius, near the elbow exit, and are {approx}11% and 14% greater, respectively, than those predicted in the baseline calculation; secondary maxima in both quantities still occur near the elbow entrance on the inner radius. Which set of results better reflects reality must await experimental corroboration. Additional calculations demonstrate that whether or not FLUENT's radial equilibrium pressure distribution option is used in the PRESSURE OUTLET boundary condition has no significant impact on the flowfield near the elbow. Simulations performed with and without the chemical sensor and associated support bracket that were present in the experiments demonstrate that the latter have a negligible influence on the flow in the vicinity of the elbow. The fact that the maxima in wall shear stress and turbulent kinetic energy occur on the inner radius is therefore not an artifact of having introduced the sensor into the flow.« less

Pics d'accélération du mouvement sismique observés lors du séisme de Chichi à Taiwan : application à l'estimation de l'aléa sismiqueAnalysis of peak ground accelerations during the Chichi earthquake, Taiwan: application to seismic hazard evaluation

NASA Astrophysics Data System (ADS)

Chang, Tsui-Yu; Cotton, Fabrice; Angelier, Jacques; Shin, Tzay-Chyn

2001-07-01

Attenuation laws are widely used in order to estimate the peak ground acceleration that may occur at a given locality during an earthquake, for hazard evaluation purposes. However, these simplified laws should be regarded acceptable only in the first approximation, because numerous significant parameters at the local and regional scales are often ignored. We examined the relationship between distance and peak acceleration based on examples from the dense accelerometric network of Taiwan, specifically for the Chichi destructive earthquake. We thus observed significant discrepancies between the predicted and observed accelerations, resulting from (1) near-field saturation, (2) amplification in sedimentary basins, and (3) hanging wall effect. We mapped the residual accelerations (difference between observed and predicted peak ground accelerations). This highlights the role of the regional structure, independently revealed by the geological analysis, as a significant factor that controls the transmission of the seismic accelerations.

X-ray photoelectron spectroscopy and secondary electron yield analysis of Al and Cu samples exposed to an accelerator environment

NASA Astrophysics Data System (ADS)

Rosenberg, R. A.; McDowell, M. W.; Ma, Q.; Harkay, K. C.

2003-09-01

It is well known that exposure to an accelerator environment can cause ``conditioning'' of the vacuum chamber surfaces. In order to understand the manner in which the surface structure might influence the production of gases and electrons in the accelerator, such surfaces should be studied both before and after exposure to accelerator conditions. Numerous studies have been performed on representative materials prior to being inserted into an accelerator, but very little has been done on materials that have ``lived'' in the accelerator for extended periods. In the present work, we mounted Al and Cu coupons at different positions in a section of the Advanced Photon Source storage ring and removed them following exposures ranging from 6 to 18 months. X-ray photoelectron spectroscopy (XPS) of the surface was performed before and after exposure. Changes were observed that depended on the location and whether the coupon was facing the chamber interior or chamber wall. These results will be presented and compared to XPS and secondary electron yield data obtained from laboratory measurements meant to simulate the accelerator conditions.

Pulsating Flows in a Tube with Expandable Wall

NASA Astrophysics Data System (ADS)

Raguso, Frank; Goushcha, Oleg

2017-11-01

A mean axial fluid flow inside a cardiovascular system has a periodic behavior driven by a heart. In one period, the flow through aorta is accelerated to a Reynolds number associated with turbulent flow and decelerated to nearly stagnant condition. The cyclic pressure in the aorta also exerts time-dependent forces on the walls of the cardiovascular system. Since walls are not rigid, they can expand under fluidic pressure. It is of interest to examine the effect of expandable walls on the flow regime transition. To achieve this, an experimental apparatus has been set up. The periodic mean axial flow inside the tubes is driven by a motor-controlled piston programmed to induce a periodic flow. A time-resolved particle image velocimetry method has been used to calculate the flow velocity field in two tubes: (1) a rigid tube and (2) a flexible tube with expandable walls. The velocity fields from two tubes were comparted to identify any differences in flow transition mechanisms.

The influence of geopolitical change on the well-being of a population: the Berlin Wall.

PubMed

Héon-Klin, V; Sieber, E; Huebner, J; Fullilove, M T

2001-03-01

Social cohesion is recognized as a fundamental condition for healthy populations, but social cohesion itself arises from political unity. The history of the Berlin Wall provides a unique opportunity to examine the effects of partition on social cohesion and, by inference, on health. This ethnographic study consisted of examination of the territory formerly occupied by the Wall, formal and informal interviews with Berlin residents, and collection of cultural documents related to the Wall. Transcripts, field notes, and documents were examined by means of a keyword-in-context analysis. The separation of Berlin into 2 parts was a traumatic experience for the city's residents. After partition, East and West Germany had divergent social, cultural, and political experiences and gradually grew apart. The demolition of the Wall--the symbol and the instrument of partition--makes possible but does not ensure the reintegration of 2 populations that were separated for 40 years. The evolution of a new common culture might be accelerated by active attempts at cultural and social exchange.

GPU accelerated simulations of three-dimensional flow of power-law fluids in a driven cube

NASA Astrophysics Data System (ADS)

Jin, K.; Vanka, S. P.; Agarwal, R. K.; Thomas, B. G.

2017-01-01

Newtonian fluid flow in two- and three-dimensional cavities with a moving wall has been studied extensively in a number of previous works. However, relatively a fewer number of studies have considered the motion of non-Newtonian fluids such as shear thinning and shear thickening power law fluids. In this paper, we have simulated the three-dimensional, non-Newtonian flow of a power law fluid in a cubic cavity driven by shear from the top wall. We have used an in-house developed fractional step code, implemented on a Graphics Processor Unit. Three Reynolds numbers have been studied with power law index set to 0.5, 1.0 and 1.5. The flow patterns, viscosity distributions and velocity profiles are presented for Reynolds numbers of 100, 400 and 1000. All three Reynolds numbers are found to yield steady state flows. Tabulated values of velocity are given for the nine cases studied, including the Newtonian cases.

Performance of masonry enclosure walls: lessons learned from recent earthquakes

NASA Astrophysics Data System (ADS)

Vicente, Romeu Silva; Rodrigues, Hugo; Varum, Humberto; Costa, Aníbal; Mendes da Silva, José António Raimundo

2012-03-01

This paper discusses the issue of performance requirements and construction criteria for masonry enclosure and infill walls. Vertical building enclosures in European countries are very often constituted by non-load-bearing masonry walls, using horizontally perforated clay bricks. These walls are generally supported and confined by a reinforced concrete frame structure of columns and beams/slabs. Since these walls are commonly considered to be nonstructural elements and their influence on the structural response is ignored, their consideration in the design of structures as well as their connection to the adjacent structural elements is frequently negligent or insufficiently detailed. As a consequence, nonstructural elements, as for wall enclosures, are relatively sensitive to drift and acceleration demands when buildings are subjected to seismic actions. Many international standards and technical documents stress the need for design acceptability criteria for nonstructural elements, however they do not specifically indicate how to prevent collapse and severe cracking, and how to enhance the overall stability in the case of moderate to high seismic loading. Furthermore, a review of appropriate measures to improve enclosure wall performance and both in-plane and out-of-plane integrity under seismic actions is addressed.

TU-H-BRA-01: The Physics of High Power Radiofrequency Isolation in a Novel Compact Linear Accelerator Based MRI Guided Radiation Therapy System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lamb, J; Low, D; Mutic, S

Purpose: To develop a method for isolating the radiofrequency waves emanating from linear accelerator components from the magnetic resonance imaging (MRI) system of an integrated MRI-linac. Methods: An MRI-guided radiation therapy system has been designed that integrates a linear accelerator with simultaneous MR imaging. The radiofrequency waves created by the accelerating process would degrade MR image quality, so a method for containing the radiofrequency waves and isolating the MR imager from them was developed. The linear accelerator radiofrequency modulator was placed outside the room, so a filter was designed to eliminate the radiofrequency corresponding to the proton Larmour frequency ofmore » 14.7 MHz. Placing the radiofrequency emitting components in a typical Faraday cage would have reduced the radiofrequency emissions, but the design would be susceptible to small gaps in the shield due to the efficiency of the Faraday cage reflecting internal radiofrequency emissions. To reduce internal radiofrequency reflections, the Faraday cage was lined with carbon fiber sheets. Carbon fiber has the property of attenuating the radiofrequency energy so that the overall radiofrequency field inside the Faraday cage is reduced, decreasing any radiofrequency energy emitted from small gaps in the cage walls. Results: Within a 1.2 MHz band centered on the Larmor frequency, the radiofrequency (RF) leakage from the Faraday cage was measured to be −90 dB with no RF on, −40 dB with the RF on and no shield, returning to −90 dB with the RF on and shields in place. The radiofrequency filter attenuated the linear accelerator modulator emissions in the 14.7 MHz band by 70 dB. Conclusions: One of the major challenges in designing a compact linear accelerator based MRI-guided radiation therapy system, that of isolating the high power RF system from the MRI, has been solved. The measured radiofrequency emissions are sufficiently small to enable system integration. This research was funded by ViewRay, Inc., Oakwood, OH.« less

Evaluation of clinically applied treatment beams with respect to bunker shielding parameters for a Cyberknife M6.

PubMed

Henzen, Dominik; Schmidhalter, Daniel; Zanella, Claudia Christina; Volken, Werner; Mackeprang, Paul-Henry; Malthaner, Marco; Fix, Michael Karl; Manser, Peter

2018-01-01

Compared to a conventional linear accelerator, the Cyberknife (CK) is a unique system with respect to radiation protection shielding and the variety and number of non-coplanar beams are two key components regarding this aspect. In this work, a framework to assess the direction distribution and modulation factor (MF) of clinically applied treatment beams of a CyberKnife M6 is developed. Database filtering options allow studying the influence of different parameters such as collimator types, treatment sites or different bunker sizes. A distribution of monitor units (MU) is generated by projecting treatment beams onto the walls, floor and ceiling of the CyberKnife bunker. This distribution is found to be highly heterogeneous and depending, among other parameters, on the bunker size. For our bunker design, 10%-13% of the MUs are delivered to the right and left wall, each. The floor receives more than 64% of the applied MUs, while the wall behind the patient's head is not hit by primary treatment beams. Between 0% and 5% of the total MUs are delivered to the wall at the patient's feet. This number highly depends on the treatment site, e.g., for extracranial patients no beams hit that wall. Collimator choice was found to have minor influence on the distribution of MUs. On the other hand, the MF depends on the collimator type as well as on the treatment site. The MFs (delivered MU/prescribed dose) for all treatments, all MLC treatments, cranial and extracranial treatments are 8.3, 6.4, 7.7, and 9.9 MU/cGy, respectively. The developed framework allows assessing and monitoring important parameters regarding radiation protection of a CK-M6 using the actually applied treatment beams. Furthermore, it enables evaluating different clinical and constructional situations using the filtering options. © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

Nano-G research laboratory for a spacecraft

NASA Technical Reports Server (NTRS)

Vonbun, Friedrich O. (Inventor); Garriott, Owen K. (Inventor)

1991-01-01

An acceleration free research laboratory is provided that is confined within a satellite but free of any physical engagement with the walls of the satellite, wherein the laboratory has adequate power, heating, cooling, and communications services to conduct basic research and development. An inner part containing the laboratory is positioned at the center-of-mass of a satellite within the satellite's outer shell. The satellite is then positioned such that its main axes are in a position parallel to its flight velocity vector or in the direction of the residual acceleration vector. When the satellite is in its desired orbit, the inner part is set free so as to follow that orbit without contacting the inside walls of the outer shell. Sensing means detect the position of the inner part with respect to the outer shell, and activate control rockets to move the outer shell; thereby, the inner part is repositioned such that it is correctly positioned at the center-of-mass of the satellite. As a consequence, all disturbing forces, such as drag forces, act on the outer shell, and the inner part containing the laboratory is shielded and is affected only by gravitational forces. Power is supplied to the inner part and to the laboratory by a balanced microwave/laser link which creates the kind of environment necessary for basic research to study critical phenomena such as the Lambda transition in helium and crystal growth, and to perform special metals and alloys research, etc.

Car-Crash Experiment for the Undergraduate Laboratory

ERIC Educational Resources Information Center

Ball, Penny L.; And Others

1974-01-01

Describes an interesting, inexpensive, and highly motivating experiment to study uniform and accelerated motion by measuring the position of a car as it crashes into a rigid wall. Data are obtained from a sequence of pictures made by a high speed camera. (Author/SLH)

Low-noise nozzle valve

NASA Technical Reports Server (NTRS)

Gwin, Hal S. (Inventor); Aaron, James (Inventor)

1990-01-01

A low noise, variable discharage area, valve is constructed having opposed recesses within which a pair of gates are slidably disposed. Each of the gates is provided with upstream edges having a radius thereon, the radius enabling smooth, accelerated, low noise flow therebetween. The gates are further provided with tracks along each side, which in turn slide along splines set in the side walls of the valve. A threaded rod which rotates in a threaded insert in a rear wall of each of the gates, serves to move the gates within their respective recesses.

Coexistence of bounded and unbounded motions in a bouncing ball model

NASA Astrophysics Data System (ADS)

Marò, Stefano

2013-05-01

We consider the model describing the vertical motion of a ball falling with constant acceleration on a wall and elastically reflected. The wall is supposed to move in the vertical direction according to a given periodic function f. We apply the Aubry-Mather theory to the generating function in order to prove the existence of bounded motions with prescribed mean time between the bounces. As the existence of unbounded motions is known, it is possible to find a class of functions f that allow both bounded and unbounded motions.

Turbulent boundary layer on a convex, curved surface

NASA Technical Reports Server (NTRS)

Gillis, J. C.; Johnston, J. P.; Kays, W. M.; Moffat, R. J.

1980-01-01

The effects of strong convex curvature on boundary layer turbulence were investigated. The data gathered on the behavior of Reynolds stress suggested the formulation of a simple turbulence model. Three sets of data were taken on two separate facilities. Both rigs had flow from a flat surface, over a convex surface with 90 deg of turning, and then onto a flat recovery surface. The geometry was adjusted so that, for both rigs, the pressure gradient along the test surface was zero - thus avoiding any effects of streamwise acceleration on the wall layers. Results show that after a sudden introduction of curvature, the shear stress in the outer part of the boundary layer is sharply diminished and is even slightly negative near the edge. The wall shear also drops off quickly downstream. In contrast, when the surface suddenly becomes flat again, the wall shear and shear stress profiles recover very slowly towards flat wall conditions.

The structural response of a rail accelerator

NASA Technical Reports Server (NTRS)

Wang, S. Y.

1983-01-01

The transient response of a 0.4 by 0.6 cm rectangular bore rail accelerator was analyzed by a three dimensional finite element code. The copper rail deflected to a peak value of 0.08 mm in compression and then oscillated at an amplitude of 0.02 mm. Simultaneously the insulating side wall of glass fabric base, epoxy resin laminate (G-1o) was compressed to a peak value of 0.13 mm and rebounded to a steady state in extension. Projectile pinch or blowby due to the rail extension or compression, respectively, can be identified by examining the time history of the rail displacement. The effect of blowby was most significant at the side wall characterized by mm size displacement in compression. Dynamic stress calculations indicate that the G-10 supporting material behind the rail is subjected to over 21 MPa at which the G-10 could fail if the laminate was not carefully oriented. Results for a polycarbonate resin (Lexan) side wall show much larger displacements and stresses than for G-10. The tradeoff between the transparency of Lexan and the mechanical strength of G-10 for sidewall material is obvious. Displacement calculations from the modal method are smaller than the results from the direct integration method by almost an order of magnitude, because the high frequency effect is neglected.

Development of heat-storage building materials for passive-solar applications

NASA Astrophysics Data System (ADS)

Fletcher, J. W.

A heat storage building material to be used for passive solar applications and general load leveling within building spaces was developed. Specifically, PCM-filled plastic panels are to be developed as wallboard and ceiling panels. Three PCMs (CaCl2, 6H2O; Na2SO4, 10H2O; LiNO3, 3H2O are to be evaluated for use in the double walled, hollow channeled plastic panels. Laboratory development of the panels will include determination of filling and sealing techniques, behavior of the PCMs, container properties and materials compatibility. Testing will include vapor transmission, thermal cycle, dynamic performance, accelerated life and durability tests. In addition to development and testing, an applications analysis will be performed for specific passive solar applications. Conceptual design of a single family passive solar residence will be prepared and performance evaluated. Screening of the three PCM candidates is essentially complete.

Shielding analyses of an AB-BNCT facility using Monte Carlo simulations and simplified methods

NASA Astrophysics Data System (ADS)

Lai, Bo-Lun; Sheu, Rong-Jiun

2017-09-01

Accurate Monte Carlo simulations and simplified methods were used to investigate the shielding requirements of a hypothetical accelerator-based boron neutron capture therapy (AB-BNCT) facility that included an accelerator room and a patient treatment room. The epithermal neutron beam for BNCT purpose was generated by coupling a neutron production target with a specially designed beam shaping assembly (BSA), which was embedded in the partition wall between the two rooms. Neutrons were produced from a beryllium target bombarded by 1-mA 30-MeV protons. The MCNP6-generated surface sources around all the exterior surfaces of the BSA were established to facilitate repeated Monte Carlo shielding calculations. In addition, three simplified models based on a point-source line-of-sight approximation were developed and their predictions were compared with the reference Monte Carlo results. The comparison determined which model resulted in better dose estimation, forming the basis of future design activities for the first ABBNCT facility in Taiwan.

Experimental Characterization of a Plasma Deflagration Accelerator for Simulating Fusion Wall Response to Disruption Events

NASA Astrophysics Data System (ADS)

Underwood, Thomas; Loebner, Keith; Cappelli, Mark

2016-10-01

In this work, the suitability of a pulsed deflagration accelerator to simulate the interaction of edge-localized modes with plasma first wall materials is investigated. Experimental measurements derived from a suite of diagnostics are presented that focus on the both the properties of the plasma jet and the manner in which such jets couple with material interfaces. Detailed measurements of the thermodynamic plasma state variables within the jet are presented using a quadruple Langmuir probe operating in current-saturation mode. This data in conjunction with spectroscopic measurements of H α Stark broadening via a fast-framing, intensified CCD camera provide spatial and temporal measurements of how the plasma density and temperature scale as a function of input energy. Using these measurements, estimates for the energy flux associated with the deflagration accelerator are found to be completely tunable over a range spanning 150 MW m-2 - 30 GW m-2. The plasma-material interface is investigated using tungsten tokens exposed to the plasma plume under variable conditions. Visualizations of resulting shock structures are achieved through Schlieren cinematography and energy transfer dynamics are discussed by presenting temperature measurements of exposed materials. This work is supported by the U.S. Department of Energy Stewardship Science Academic Program in addition to the National Defense Science Engineering Graduate Fellowship.

Comparison of the effects of antihypertensive treatment with angiotensin II blockade and beta-blockade on carotid wall structure and haemodynamics: protocol and baseline demographics.

PubMed

Ariff, Ben; Stanton, Alice; Barratt, Dean; Augst, Alex; Glor, Fadi; Poulter, Neil; Sever, Peter; Xu, Yun; Hughes, Alun; Thom, Simon A Mc G

2002-06-01

Several systemic factors have been shown to contribute to the acceleration of large vessel atheroma. Correction of these factors leads to a reduction in the progression of plaque formation and associated arterial wall thickness. Atheroma remains, however, a focal disease, developing at characteristic sites within the arterial tree. These sites are typically at areas of vessel branching or marked curvature, and correspond to regions of high tensile stress and low sheer stress, leading to the hypothesis that local haemodynamic factors and vessel wall mechanics potentiate the focal development of atheroma. Current assessment of vascular haemodynamics suffers from an inability to handle complex flow, and does not allow accurate determination of locally varying flow, and shear stress patterns. The application of computational fluid dynamic (CFD) flow simulation techniques to ultrasound and local pressure data, however, allows a comprehensive, non-invasive appraisal of haemodynamic flow parameters to be performed. The Candesartan cilexetil and Atenolol Carotid Haemodynamic Endpoint Trial (CACHET) study compares the effects of two antihypertensive regimens, one b-blocker-based, the other angiotensin receptor blocker based, on carotid intima-media thickness. The collection of ultrasound and pressure data on each subject provides a unique opportunity to apply these data to the CFD model to study the effects of these antihypertensive regimens on local fluid dynamics. This will lead to a greater understanding of the relationship of these factors to atheroma formation and regression.

Accelerated procedure to solve kinetic equation for neutral atoms in a hot plasma

NASA Astrophysics Data System (ADS)

Tokar, Mikhail Z.

2017-12-01

The recombination of plasma charged components, electrons and ions of hydrogen isotopes, on the wall of a fusion reactor is a source of neutral molecules and atoms, recycling back into the plasma volume. Here neutral species participate, in particular, in charge-exchange (c-x) collisions with the plasma ions and, as a result, atoms of high energies with chaotically directed velocities are generated. Some fraction of these hot atoms hit the wall. Statistical Monte Carlo methods normally used to model c-x atoms are too time consuming for reasonably small level of accident errors and extensive parameter studies are problematic. By applying pass method to evaluate integrals from functions, including the ion velocity distribution, an iteration approach to solve one-dimensional kinetic equation [1], being alternative to Monte Carlo procedure, has been tremendously accelerated, at least by a factor of 30-50 [2]. Here this approach is developed further to solve the 2-D kinetic equation, applied to model the transport of c-x atoms in the vicinity of an opening in the wall, e.g., the entrance of the duct guiding to a diagnostic installation. This is necessary to determine firmly the energy spectrum of c-x atoms penetrating into the duct and to assess the erosion of the installation there. The results of kinetic modeling are compared with those obtained with the diffusion description for c-x atoms, being strictly relevant under plasma conditions of low temperature and high density, where the mean free path length between c-x collisions is much smaller than that till the atom ionization by electrons. It is demonstrated that the previous calculations [3], done with the diffusion approximation for c-x atoms, overestimate the erosion rate of Mo mirrors in a reactor by a factor of 3 compared to the result of the present kinetic study.

Lorentz Force Detuning Analysis of the SNS Accelerating Cavities

DOE Office of Scientific and Technical Information (OSTI.GOV)

R. Mitchell; K. Matsumoto; G. Ciovati

2001-09-01

The Spallation Neutron Source (SNS) project incorporates a superconducting radio-frequency (SRF) accelerator for the final section of the pulsed mode linac Cavities with geometrical {beta} values of {beta} = 0.61 and {beta} = 0.81 are utilized in the SRF section, and are constructed out of thin-walled niobium with stiffener rings welded between the cells near the iris. The welded titanium helium vessel and tuner assembly restrains the cavity beam tubes Cavities with {beta} values less than one have relatively steep and flat side-walls making the cavities susceptible to Ised RF induces cyclic Lorentz pressures that mechanically excite the cavities, producingmore » a dynamic Lorentz force detuning different from a continuous RF system. The amplitude of the dynamic detuning for a given cavity design is a function of the mechanical damping, stiffness of the tuner/helium vessel assembly, RF pulse profile, and the RF pulse rate. This paper presents analysis and testing results to date, and indicates areas where more investigation is required.« less

Electronic Desorption of gas from metals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Molvik, A W; Kollmus, H; Mahner, E

During heavy ion operation in several particle accelerators world-wide, dynamic pressure rises of orders of magnitude were triggered by lost beam ions that bombarded the vacuum chamber walls. This ion-induced molecular desorption, observed at CERN, GSI, and BNL, can seriously limit the ion beam lifetime and intensity of the accelerator. From dedicated test stand experiments we have discovered that heavy-ion induced gas desorption scales with the electronic energy loss (dE{sub e}/dx) of the ions slowing down in matter; but it varies only little with the ion impact angle, unlike electronic sputtering.

LOADED WAVE GUIDES FOR LINEAR ACCELERATORS

DOEpatents

Walkinshaw, W.; Mullett, L.B.

1959-12-01

A periodically loaded waveguide having substantially coaxially arranged elements which provide an axial field for the acceleration of electrons is described. Radiofrequency energy will flow in the space between the inner wall of an outer guide and the peripheries of equally spaced irises or washes arranged coaxially with each other and with the outer guide, where the loading due to the geometry of the irises is such as to reduce the phase velocity of the r-f energy flowing in the guide from a value greater than that of light to the velocity of light or less.

A novel radial anode layer ion source for inner wall pipe coating and materials modification--hydrogenated diamond-like carbon coatings from butane gas.

PubMed

Murmu, Peter P; Markwitz, Andreas; Suschke, Konrad; Futter, John

2014-08-01

We report a new ion source development for inner wall pipe coating and materials modification. The ion source deposits coatings simultaneously in a 360° radial geometry and can be used to coat inner walls of pipelines by simply moving the ion source in the pipe. Rotating parts are not required, making the source ideal for rough environments and minimizing maintenance and replacements of parts. First results are reported for diamond-like carbon (DLC) coatings on Si and stainless steel substrates deposited using a novel 360° ion source design. The ion source operates with permanent magnets and uses a single power supply for the anode voltage and ion acceleration up to 10 kV. Butane (C4H10) gas is used to coat the inner wall of pipes with smooth and homogeneous DLC coatings with thicknesses up to 5 μm in a short time using a deposition rate of 70 ± 10 nm min(-1). Rutherford backscattering spectrometry results showed that DLC coatings contain hydrogen up to 30 ± 3% indicating deposition of hydrogenated DLC (a-C:H) coatings. Coatings with good adhesion are achieved when using a multiple energy implantation regime. Raman spectroscopy results suggest slightly larger disordered DLC layers when using low ion energy, indicating higher sp(3) bonds in DLC coatings. The results show that commercially interesting coatings can be achieved in short time.

Developing xylem-preferential expression of PdGA20ox1, a gibberellin 20-oxidase 1 from Pinus densiflora, improves woody biomass production in a hybrid poplar.

PubMed

Jeon, Hyung-Woo; Cho, Jin-Seong; Park, Eung-Jun; Han, Kyung-Hwan; Choi, Young-Im; Ko, Jae-Heung

2016-04-01

Woody biomass has gained popularity as an environmentally friendly, renewable and sustainable resource for liquid fuel production. Here, we demonstrate biotechnological improvement of the quantity and quality of woody biomass by employing developing xylem (DX)-preferential production of gibberellin (GA), a phytohormone that positively regulates stem growth. First, for the proof of concept experiment, we produced transgenic Arabidopsis plants expressing GA20-oxidase, a key enzyme in the production of bioactive GAs, from Pinus densiflora (PdGA20ox1) under the control of either a constitutive 35S promoter, designated 35S::PdGA20ox1, or a DX-specific promoter (originated from poplar), designated DX15::PdGA20ox1. As we hypothesized, both transgenic Arabidopsis plants (35S::PdGA20ox1 and DX15::PdGA20ox1) exhibited an accelerated stem growth that resulted in a large increase of biomass, up to 300% compared to wild-type control plants, together with increased secondary wall thickening and elongation of fibre cells. Next, we applied our concept to the production of transgenic poplar trees. Both transgenic poplar trees (35S::PdGA20ox1 and DX15::PdGA20ox1) showed dramatic increases in biomass, up to 300%, with accelerated stem growth and xylem differentiation. Cell wall monosaccharide composition analysis revealed that in both Arabidopsis and poplar, glucose and xylose contents were significantly increased. However, undesirable phenotypes of 35S::PdGA20ox1 poplar, including poor root growth and leaf development, were found. Interestingly, DX15::PdGA20ox1 poplar resulted in a reduction of undesirable phenotypes. Our results indicate that the controlled production of GAs through a tissue-specific promoter can be utilized as an efficient biotechnological tool for producing enhanced plant biomass, minimizing unwanted effects. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

Genome-wide analyses of late pollen-preferred genes conserved in various rice cultivars and functional identification of a gene involved in the key processes of late pollen development.

PubMed

Moon, Sunok; Oo, Moe Moe; Kim, Backki; Koh, Hee-Jong; Oh, Sung Aeong; Yi, Gihwan; An, Gynheung; Park, Soon Ki; Jung, Ki-Hong

2018-04-23

Understanding late pollen development, including the maturation and pollination process, is a key component in maintaining crop yields. Transcriptome data obtained through microarray or RNA-seq technologies can provide useful insight into those developmental processes. Six series of microarray data from a public transcriptome database, the Gene Expression Omnibus of the National Center for Biotechnology Information, are related to anther and pollen development. We performed a systematic and functional study across the rice genome of genes that are preferentially expressed in the late stages of pollen development, including maturation and germination. By comparing the transcriptomes of sporophytes and male gametes over time, we identified 627 late pollen-preferred genes that are conserved among japonica and indica rice cultivars. Functional classification analysis with a MapMan tool kit revealed a significant association between cell wall organization/metabolism and mature pollen grains. Comparative analysis of rice and Arabidopsis demonstrated that genes involved in cell wall modifications and the metabolism of major carbohydrates are unique to rice. We used the GUS reporter system to monitor the expression of eight of those genes. In addition, we evaluated the significance of our candidate genes, using T-DNA insertional mutant population and the CRISPR/Cas9 system. Mutants from T-DNA insertion and CRISPR/Cas9 systems of a rice gene encoding glycerophosphoryl diester phosphodiesterase are defective in their male gamete transfer. Through the global analyses of the late pollen-preferred genes from rice, we found several biological features of these genes. First, biological process related to cell wall organization and modification is over-represented in these genes to support rapid tube growth. Second, comparative analysis of late pollen preferred genes between rice and Arabidopsis provide a significant insight on the evolutional disparateness in cell wall biogenesis and storage reserves of pollen. In addition, these candidates might be useful targets for future examinations of late pollen development, and will be a valuable resource for accelerating the understanding of molecular mechanisms for pollen maturation and germination processes in rice.

Present Status and Future Developments in Proton Therapy

NASA Astrophysics Data System (ADS)

Smith, Alfred R.

2009-07-01

Within the past few years, interest in proton therapy has significantly increased. This interest has been generated by a number of factors including: 1) the reporting of positive clinical results using proton beams; 2) approval of reimbursement for delivery of proton therapy; 3) the success of hospital-based proton therapy centers; and 4) the availability of modern, integrated proton therapy technology for hospital-based facilities. In the United States, this increased interest has occurred particularly at the level of smaller academic hospitals, community medical centers, and large private practices; however, interest from large academic centers continues to be strong. Particular interest exists regarding smaller and less-expensive proton therapy systems, especially the so-called "single-room" systems. In this paper, the advantages and disadvantages of 1-room proton therapy systems will be discussed. The emphasis on smaller and cheaper proton therapy facilities has also generated interest in new proton-accelerating technologies such as superconducting cyclotrons and synchrocyclotrons, laser acceleration, and dielectric-wall accelerators. Superconducting magnets are also being developed to decrease the size and weight of isocentric gantries. Another important technical development is spot-beam scanning, which offers the ability to deliver intensity-modulated proton treatments (IMPT). IMPT has the potential to provide dose distributions that are superior to those for photon intensity modulation techniques (IMXT) and to improve clinical outcomes for patients undergoing cancer therapy. At the present time, only two facilities—one in Europe and one in the United States—have the ability to deliver IMPT treatments, however, within the next year or two several additional facilities are expected to achieve this capability.

Free surface deformation and heat transfer by thermocapillary convection

NASA Astrophysics Data System (ADS)

Fuhrmann, Eckart; Dreyer, Michael; Basting, Steffen; Bänsch, Eberhard

2016-04-01

Knowing the location of the free liquid/gas surface and the heat transfer from the wall towards the fluid is of paramount importance in the design and the optimization of cryogenic upper stage tanks for launchers with ballistic phases, where residual accelerations are smaller by up to four orders of magnitude compared to the gravity acceleration on earth. This changes the driving forces drastically: free surfaces become capillary dominated and natural or free convection is replaced by thermocapillary convection if a non-condensable gas is present. In this paper we report on a sounding rocket experiment that provided data of a liquid free surface with a nonisothermal boundary condition, i.e. a preheated test cell was filled with a cold but storable liquid in low gravity. The corresponding thermocapillary convection (driven by the temperature dependence of the surface tension) created a velocity field directed away from the hot wall towards the colder liquid and then in turn back at the bottom towards the wall. A deformation of the free surface resulting in an apparent contact angle rather different from the microscopic one could be observed. The thermocapillary flow convected the heat from the wall to the liquid and increased the heat transfer compared to pure conduction significantly. The paper presents results of the apparent contact angle as a function of the dimensionless numbers (Weber-Marangoni and Reynolds-Marangoni number) as well as heat transfer data in the form of a Nusselt number. Experimental results are complemented by corresponding numerical simulations with the commercial software Flow3D and the inhouse code Navier.

Bicuspid aortic valves are associated with increased wall and turbulence shear stress levels compared to trileaflet aortic valves.

PubMed

Saikrishnan, Neelakantan; Mirabella, Lucia; Yoganathan, Ajit P

2015-06-01

Congenital bicuspid aortic valves (BAVs) are associated with accelerated disease progression, such as leaflet calcification and ascending aorta dilatation. Although common underlying genetic factors have been implicated in accelerated disease in BAV patients, several studies have suggested that altered hemodynamics also play a role in this disease process. The present study compares turbulence and wall shear stress (WSS) measurements between various BAV and trileaflet aortic valve (TAV) models to provide information for mechanobiological models of BAV disease. BAV and TAV models were constructed from excised porcine aortic valves to simulate parametric variations in BAV stenosis, hemodynamics and geometry. Particle image velocimetry experiments were conducted at physiological pressure conditions to characterize velocity fields in the ascending aorta. The velocity fields were post-processed to calculate turbulence, viscous and wall shear stresses in the ascending aorta. Stenosed BAV models showed the presence of eccentric systolic jets, causing increased WSS. Lower cardiac output resulted in a narrower jet, lower turbulence and lower viscous shear stress (VSS). The specific severe stenosis BAV model studied here showed reduced WSS due to reduction in non-fused leaflet mobility. Dilation of the aorta did not affect any turbulence or VSS, but reduced the WSS. In comparison with BAVs, TAVs have similar VSS values, but much smaller WSS and turbulence levels. These increased turbulence  and WSS levels in BAVs may play a key role in amplifying the biological responses of the ascending aorta wall and valvular leaflets, and support the hemodynamic underpinnings of BAV disease processes.

Special issue on compact x-ray sources

NASA Astrophysics Data System (ADS)

Hooker, Simon; Midorikawa, Katsumi; Rosenzweig, James

2014-04-01

Journal of Physics B: Atomic, Molecular and Optical Physics is delighted to announce a forthcoming special issue on compact x-ray sources, to appear in the winter of 2014, and invites you to submit a paper. The potential for high-brilliance x- and gamma-ray sources driven by advanced, compact accelerators has gained increasing attention in recent years. These novel sources—sometimes dubbed 'fifth generation sources'—will build on the revolutionary advance of the x-ray free-electron laser (FEL). New radiation sources of this type have widespread applications, including in ultra-fast imaging, diagnostic and therapeutic medicine, and studies of matter under extreme conditions. Rapid advances in compact accelerators and in FEL techniques make this an opportune moment to consider the opportunities which could be realized by bringing these two fields together. Further, the successful development of compact radiation sources driven by compact accelerators will be a significant milestone on the road to the development of high-gradient colliders able to operate at the frontiers of particle physics. Thus the time is right to publish a peer-reviewed collection of contributions concerning the state-of-the-art in: advanced and novel acceleration techniques; sophisticated physics at the frontier of FELs; and the underlying and enabling techniques of high brightness electron beam physics. Interdisciplinary research connecting two or more of these fields is also increasingly represented, as exemplified by entirely new concepts such as plasma based electron beam sources, and coherent imaging with fs-class electron beams. We hope that in producing this special edition of Journal of Physics B: Atomic, Molecular and Optical Physics (iopscience.iop.org/0953-4075/) we may help further a challenging mission and ongoing intellectual adventure: the harnessing of newly emergent, compact advanced accelerators to the creation of new, agile light sources with unprecedented capabilities. New schemes for compact accelerators: laser- and beam-driven plasma accelerators; dielectric laser accelerators; THz accelerators. Latest results for compact accelerators. Target design and staging of advanced accelerators. Advanced injection and phase space manipulation techniques. Novel diagnostics: single-shot measurement of sub-fs bunch duration; measurement of ultra-low emittance. Generation and characterization of incoherent radiation: betatron and undulator radiation; Thomson/Compton scattering sources, novel THz sources. Generation and characterization of coherent radiation. Novel FEL simulation techniques. Advances in simulations of novel accelerators: simulations of injection and acceleration processes; simulations of coherent and incoherent radiation sources; start-to-end simulations of fifth generation light sources. Novel undulator schemes. Novel laser drivers for laser-driven accelerators: high-repetition rate laser systems; high wall-plug efficiency systems. Applications of compact accelerators: imaging; radiography; medical applications; electron diffraction and microscopy. Please submit your article by 15 May 2014 (expected web publication: winter 2014); submissions received after this date will be considered for the journal, but may not be included in the special issue.

Applications of the ram accelerator to hypervelocity aerothermodynamic testing

NASA Technical Reports Server (NTRS)

Bruckner, A. P.; Knowlen, C.; Hertzberg, A.

1992-01-01

A ram accelerator used as a hypervelocity launcher for large-scale aeroballistic range applications in hypersonics and aerodynamics research is presented. It is an in-bore ramjet device in which a projectile shaped like the centerbody of a supersonic ramjet is propelled down a stationary tube filled with a tailored combustible gas mixture. Ram accelerator operation has been demonstrated at 39 mm and 90 mm bores, supporting the proposition that this launcher concept can be scaled up to very large bore diameters of the order of 30-60 cm. It is concluded that high quality data obtained from the tube wall and projectile during the aceleration process itself are very useful for understanding aerothermodynamics of hypersonic flow in general, and for providing important CFD validation benchmarks.

Building vibrations induced by noise from rotorcraft and propeller aircraft flyovers

NASA Technical Reports Server (NTRS)

Shepherd, Kevin P.; Hubbard, Harvey H.

1992-01-01

Noise and building vibrations were measured for a series of helicopter and propeller-driven aircraft flyovers at WFF during May 1978. The building response data are compared with similar data acquired earlier at sites near Dulles and Kennedy Airports for operation of commercial jet transports, including the Concorde supersonic transport. Results show that noise-induced vibration levels in windows and walls are directly proportional to sound pressure level and that for a given noise level, the acceleration levels induced by a helicopter or a propeller-driven aircraft flyover cannot be distinguished from the acceleration levels induced by a commercial jet transport flyover. Noise-induced building acceleration levels were found to be lower than those levels which might be expected to cause structural damage and were also lower than some acceleration levels induced by such common domestic events as closing windows and doors.

Development of new S-band RF window for stable high-power operation in linear accelerator RF system

NASA Astrophysics Data System (ADS)

Joo, Youngdo; Lee, Byung-Joon; Kim, Seung-Hwan; Kong, Hyung-Sup; Hwang, Woonha; Roh, Sungjoo; Ryu, Jiwan

2017-09-01

For stable high-power operation, a new RF window is developed in the S-band linear accelerator (Linac) RF systems of the Pohang Light Source-II (PLS-II) and the Pohang Accelerator Laboratory X-ray Free-Electron Laser (PAL-XFEL). The new RF window is designed to mitigate the strength of the electric field at the ceramic disk and also at the waveguide-cavity coupling structure of the conventional RF window. By replacing the pill-box type cavity in the conventional RF window with an overmoded cavity, the electric field component perpendicular to the ceramic disk that caused most of the multipacting breakdowns in the ceramic disk was reduced by an order of magnitude. The reduced electric field at the ceramic disk eliminated the Ti-N coating process on the ceramic surface in the fabrication procedure of the new RF window, preventing the incomplete coating from spoiling the RF transmission and lowering the fabrication cost. The overmoded cavity was coupled with input and output waveguides through dual side-wall coupling irises to reduce the electric field strength at the waveguide-cavity coupling structure and the possibility of mode competitions in the overmoded cavity. A prototype of the new RF window was fabricated and fully tested with the Klystron peak input power, pulse duration and pulse repetition rate of 75 MW, 4.5 μs and 10 Hz, respectively, at the high-power test stand. The first mass-produced new RF window installed in the PLS-II Linac is running in normal operation mode. No fault is reported to date. Plans are being made to install the new RF window to all S-band accelerator RF modules of the PLS-II and PAL-XFEL Linacs. This new RF window may be applied to the output windows of S-band power sources like Klystron as wells as the waveguide windows of accelerator facilities which operate in S-band.

Ion source development for a photoneutralization based NBI system for fusion reactors

NASA Astrophysics Data System (ADS)

Simonin, A.; de Esch, H. P. L.; Garibaldi, P.; Grand, C.; Bechu, S.; Bès, A.; Lacoste, A.

2015-04-01

The next step after ITER is to demonstrate the viability and generation of electricity by a future fusion reactor (DEMO). The specifications required to operate an NBI system on DEMO are very demanding. The system has to provide a very high level of power and energy, ~100MW of D° beam at 1MeV, including high wall-plug efficiency (η > 60%). For this purpose, a new injector concept, called Siphore, is under investigation between CEA and French universities. Siphore is based on the stripping of the accelerated negative ions by photo-detachment provided by several Fabry-Perot cavities (3.5MW of light power per cavity) implemented along the D- beam. The beamline is designed to be tall and narrow in order that the photon flux overlaps the entire negative ion beam. The paper will describe the present R&D at CEA which addresses the development of an ion source and pre-accelerator prototypes for Siphore, the main goal being to produce an intense negative ion beam sheet. The negative ion source Cybele is based on a magnetized plasma column where hot electrons are emitted from the source center. Parametric studies of the source are performed using Langmuir probes in order to characterize the plasma and to compare with numerical models being developed in French universities.

Investigation of radiofrequency plasma sources for space travel

NASA Astrophysics Data System (ADS)

Charles, C.; Boswell, R. W.; Takahashi, K.

2012-12-01

Optimization of radiofrequency (RF) plasma sources for the development of space thrusters differs from other applications such as plasma processing of materials since power efficiency, propellant usage, particle acceleration or heating become driving parameters. The development of two RF (13.56 MHz) plasma sources, the high-pressure (˜1 Torr) capacitively coupled ‘pocket rocket’ plasma micro-thruster and the low-pressure (˜1 mTorr) inductively coupled helicon double layer thruster (HDLT), is discussed within the context of mature and emerging electric propulsion devices. The density gradient in low-pressure expanding RF plasmas creates an electric field that accelerates positive ions out of the plasma. Generally, the total potential drop is similar to that of a wall sheath allowing the plasma electrons to neutralize the ion beam. A high-pressure expansion with no applied magnetic field can result in large dissociation rates and/or a collimated beam of ions of small area and a flowing heated neutral beam (‘pocket rocket’). A low-pressure expansion dominated by a magnetic field can result in the formation of electric double layers which produce a very directed neutralized beam of ions of large area (HDLT).

Products Released from Enzymically Active Cell Wall Stimulate Ethylene Production and Ripening in Preclimacteric Tomato (Lycopersicon esculentum Mill.) Fruit 1

PubMed Central

Brecht, Jeffrey K.; Huber, Donald J.

1988-01-01

Enzymically active cell wall from ripe tomato (Lycopersicon esculentum Mill.) fruit pericarp release uronic acids through the action of wall-bound polygalacturonase. The potential involvement of products of wall hydrolysis in the induction of ethylene synthesis during tomato ripening was investigated by vacuum infiltrating preclimacteric (green) fruit with solutions containing pectin fragments enzymically released from cell wall from ripe fruit. Ripening initiation was accelerated in pectin-infiltrated fruit compared to control (buffer-infiltrated) fruit as measured by initiation of climacteric CO2 and ethylene production and appearance of red color. The response to infiltration was maximum at a concentration of 25 micrograms pectin per fruit; higher concentrations (up to 125 micrograms per fruit) had no additional effect. When products released from isolated cell wall from ripe pericarp were separated on Bio-Gel P-2 and specific size classes infiltrated into preclimacteric fruit, ripening-promotive activity was found only in the larger (degree of polymerization >8) fragments. Products released from pectin derived from preclimacteric pericarp upon treatment with polygalacturonase from ripe pericarp did not stimulate ripening when infiltrated into preclimacteric fruit. PMID:16666417

Phase-sensitive dual-inversion recovery for accelerated carotid vessel wall imaging.

PubMed

Bonanno, Gabriele; Brotman, David; Stuber, Matthias

2015-03-01

Dual-inversion recovery (DIR) is widely used for magnetic resonance vessel wall imaging. However, optimal contrast may be difficult to obtain and is subject to RR variability. Furthermore, DIR imaging is time-inefficient and multislice acquisitions may lead to prolonged scanning times. Therefore, an extension of phase-sensitive (PS) DIR is proposed for carotid vessel wall imaging. The statistical distribution of the phase signal after DIR is probed to segment carotid lumens and suppress their residual blood signal. The proposed PS-DIR technique was characterized over a broad range of inversion times. Multislice imaging was then implemented by interleaving the acquisition of 3 slices after DIR. Quantitative evaluation was then performed in healthy adult subjects and compared with conventional DIR imaging. Single-slice PS-DIR provided effective blood-signal suppression over a wide range of inversion times, enhancing wall-lumen contrast and vessel wall conspicuity for carotid arteries. Multislice PS-DIR imaging with effective blood-signal suppression is enabled. A variant of the PS-DIR method has successfully been implemented and tested for carotid vessel wall imaging. This technique removes timing constraints related to inversion recovery, enhances wall-lumen contrast, and enables a 3-fold increase in volumetric coverage at no extra cost in scanning time.

On Markov modelling of near-wall turbulent shear flow

NASA Astrophysics Data System (ADS)

Reynolds, A. M.

1999-11-01

The role of Reynolds number in determining particle trajectories in near-wall turbulent shear flow is investigated in numerical simulations using a second-order Lagrangian stochastic (LS) model (Reynolds, A.M. 1999: A second-order Lagrangian stochastic model for particle trajectories in inhomogeneous turbulence. Quart. J. Roy. Meteorol. Soc. (In Press)). In such models, it is the acceleration, velocity and position of a particle rather than just its velocity and position which are assumed to evolve jointly as a continuous Markov process. It is found that Reynolds number effects are significant in determining simulated particle trajectories in the viscous sub-layer and the buffer zone. These effects are due almost entirely to the change in the Lagrangian integral timescale and are shown to be well represented in a first-order LS model by Sawford's correction footnote Sawford, B.L. 1991: Reynolds number effects in Lagrangian stochastic models of turbulent dispersion. Phys Fluids, 3, 1577-1586). This is found to remain true even when the Taylor-Reynolds number R_λ ~ O(0.1). This is somewhat surprising because the assumption of a Markovian evolution for velocity and position is strictly applicable only in the large Reynolds number limit because then the Lagrangian acceleration autocorrelation function approaches a delta function at the origin, corresponding to an uncorrelated component in the acceleration, and hence a Markov process footnote Borgas, M.S. and Sawford, B.L. 1991: The small-scale structure of acceleration correlations and its role in the statistical theory of turbulent dispersion. J. Fluid Mech. 288, 295-320.

New therapeutic options for the metabolic syndrome: what's next?

PubMed

Flordellis, Christodoulos S; Ilias, Ioannis; Papavassiliou, Athanasios G

2005-08-01

The metabolic syndrome (MSX), characterized by obesity, insulin resistance, dyslipidemia and hypertension, increases the risk of cardiovascular morbidity and mortality. It has recently been hypothesized that MSX and type 2 diabetes are caused by triglyceride and long-chain fatty acid accumulation in liver, muscle, pancreatic islets and selected brain areas. This lipocentric approach is integrated with analysis of inflammation associated with end-organ damage, including the vascular wall. Genes and proteins contributing to insulin resistance, beta cell dysfunction and vascular wall damage have been identified. Transcription factors and coactivators, including peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator-1 are crucial in mediating insulin resistance and accelerating vascular wall inflammation, and represent promising therapeutic targets. New pharmacological strategies include dual PPARalpha/gamma agonists, drugs with pleiotropic effects or combination therapies.

Diatremes and craters attributed to natural explosions

USGS Publications Warehouse

Shoemaker, Eugene Merle

1956-01-01

Diatremes - volcanic pipes attributed to explosion - and craters have been studied to infer the ultimate causes and physical conditions attending natural explosive processes. Initial piercement of diatremes on the Navajo reservation, Arizona was probably along a fracture propagated by a high-pressure aqueous fluid. Gas rising at high velocity along the fracture would become converted to a gas-solid fluidized system by entrainment of wall- rock fragments. The first stages of widening of the vent are probably accomplished mainly by simple abrasion of the high-velocity fluidized system on the walls of the fracture. As the vent widens, its enlargement may be accelerated by inward spalling of the walls. The inferred mechanics of the Navajo-Hopi diatremes is used to illustrate the possibility of diatreme formation over a molten salt mass.

The influence of geopolitical change on the well-being of a population: the Berlin Wall.

PubMed Central

Héon-Klin, V; Sieber, E; Huebner, J; Fullilove, M T

2001-01-01

OBJECTIVES: Social cohesion is recognized as a fundamental condition for healthy populations, but social cohesion itself arises from political unity. The history of the Berlin Wall provides a unique opportunity to examine the effects of partition on social cohesion and, by inference, on health. METHODS: This ethnographic study consisted of examination of the territory formerly occupied by the Wall, formal and informal interviews with Berlin residents, and collection of cultural documents related to the Wall. Transcripts, field notes, and documents were examined by means of a keyword-in-context analysis. RESULTS: The separation of Berlin into 2 parts was a traumatic experience for the city's residents. After partition, East and West Germany had divergent social, cultural, and political experiences and gradually grew apart. CONCLUSIONS: The demolition of the Wall--the symbol and the instrument of partition--makes possible but does not ensure the reintegration of 2 populations that were separated for 40 years. The evolution of a new common culture might be accelerated by active attempts at cultural and social exchange. PMID:11236400

Measuring the neck frequency response function of laryngectomy patients: Implications for the design of electrolarynx devices

NASA Astrophysics Data System (ADS)

Meltzner, Geoffrey S.; Kobler, James B.; Hillman, Robert E.

2003-08-01

Measurements of the neck frequency response function (NFRF), defined as the ratio of the spectrum of the estimated volume velocity that excites the vocal tract to the spectrum of the acceleration delivered to the neck wall, were made at three different positions on the necks of nine laryngectomized subjects (five males and four females) and four normal laryngeal speakers (two males and two females). A minishaker driven by broadband noise provided excitation to the necks of subjects as they configured their vocal tracts to mimic the production of the vowels /aye/, /æ/, and /I/. The sound pressure at the lips was measured with a microphone and an impedance head mounted on the shaker measured the acceleration. The neck wall passed low-frequency sound energy better than high-frequency sound energy, and thus the NFRF was accurately modeled as a low-pass filter. The NFRFs of the different subject groups (female laryngeal, male laryngeal speakers, laryngectomized males, and laryngectomized females) differed from each other in terms of corner frequency and gain, with both types of male subjects presenting NFRFs with larger overall gains. In addition, there was a notable amount of intersubject variability within groups. Because the NFRF is an estimate of how sound energy passes through the neck wall, these results should aid in the design of improved neck-type electrolarynx devices.

Distribution of residual long-lived radioactivity in the inner concrete walls of a compact medical cyclotron vault room.

PubMed

Fujibuchi, Toshioh; Nohtomi, Akihiro; Baba, Shingo; Sasaki, Masayuki; Komiya, Isao; Umedzu, Yoshiyuki; Honda, Hiroshi

2015-01-01

Compact medical cyclotrons have been set up to generate the nuclides necessary for positron emission tomography. In accelerator facilities, neutrons activate the concrete used to construct the vault room; this activation increases with the use of an accelerator. The activation causes a substantial radioactive waste management problem when facilities are decommissioned. In the present study, several concrete cores from the walls, ceiling and floor of a compact medical cyclotron vault room were samples 2 years after the termination of operations, and the radioactivity concentrations of radionuclides were estimated. Cylindrical concrete cores 5 cm in diameter and 10 cm in length were bored from the concrete wall, ceiling and floor. Core boring was performed at 18 points. The gamma-ray spectrum of each sample was measured using a high-purity germanium detector. The degree of activation of the concrete in the cyclotron vault room was analyzed, and the range and tendency toward activation in the vault room were examined. (60)Co and (152)Eu were identified by gamma-ray spectrometry of the concrete samples. (152)Eu and (60)Co are produced principally from the stable isotopes of europium and cobalt by neutron capture reactions. The radioactivity concentration did not vary much between the surface of the concrete and at a depth of 10 cm. Although the radioactivity concentration near the target was higher than the clearance level for radioactive waste indicated in IAEA RS-G-1.7, the mean radioactivity concentration in the walls and floor was lower than the clearance level. The radioactivity concentration of the inner concrete wall of the medical cyclotron vault room was not uniform. The areas exceeding the clearance level were in the vicinity of the target, but most of the building did not exceed the clearance levels.

The conundrum of arterial stiffness, elevated blood pressure, and aging.

PubMed

AlGhatrif, Majd; Lakatta, Edward G

2015-02-01

Isolated systolic hypertension is a major health burden that is expanding with the aging of our population. There is evidence that central arterial stiffness contributes to the rise in systolic blood pressure (SBP); at the same time, central arterial stiffening is accelerated in patients with increased SBP. This bidirectional relationship created a controversy in the field on whether arterial stiffness leads to hypertension or vice versa. Given the profound interdependency of arterial stiffness and blood pressure, this question seems intrinsically challenging, or probably naïve. The aorta's function of dampening the pulsatile flow generated by the left ventricle is optimal within a physiological range of distending pressure that secures the required distal flow, keeps the aorta in an optimal mechanical conformation, and minimizes cardiac work. This homeostasis is disturbed by age-associated, minute alterations in aortic hemodynamic and mechanical properties that induce short- and long-term alterations in each other. Hence, it is impossible to detect an "initial insult" at an epidemiological level. Earlier manifestations of these alterations are observed in young adulthood with a sharp decline in aortic strain and distensibility accompanied by an increase in diastolic blood pressure. Subsequently, aortic mechanical reserve is exhausted, and aortic remodeling with wall stiffening and dilatation ensue. These two phenomena affect pulse pressure in opposite directions and different magnitudes. With early remodeling, there is an increase in pulse pressure, due to the dominance of arterial wall stiffness, which in turn accelerates aortic wall stiffness and dilation. With advanced remodeling, which appears to be greater in men, the effect of diameter becomes more pronounced and partially offsets the effect of wall stiffness leading to plateauing in pulse pressure in men and slower increase in pulse pressure (PP) than that of wall stiffness in women. The complex nature of the hemodynamic changes with aging makes the "one-size-fits-all" approach suboptimal and urges for therapies that address the vascular profile that underlies a given blood pressure, rather than the blood pressure values themselves.

Precarious rock and overturned transformer evidence for ground shaking in the Ms 7.7 Kern County earthquake: An analog for disastrous shaking from a major thrust fault in the Los Angeles basin

USGS Publications Warehouse

Brune, J.N.; Anooshehpoor, A.; Shi, B.; Zheng, Yen

2004-01-01

Precariously balanced rocks and overturned transformers in the vicinity of the White Wolf fault provide constraints on ground motion during the 1952 Ms 7.7 Kern County earthquake, a possible analog for an anticipated large earthquake in the Los Angeles basin (Shaw et al., 2002; Dolan et al., 2003). On the northeast part of the fault preliminary estimates of ground motion on the footwall give peak accelerations considerably lower than predicted by standard regression curves. On the other hand, on the hanging-wall, there is evidence of intense ground shattering and lack of precarious rocks, consistent with the intense hanging-wall accelerations suggested by foam-rubber modeling, numerical modeling, and observations from previous thrust fault earthquakes. There is clear evidence of the effects of rupture directivity in ground motions on the hanging-wall side of the fault (from both precarious rocks and numerical simulations). On the southwest part of the fault, which is covered by sediments, the thrust fault did not reach the surface ("blind" thrust). Overturned and damaged transformers indicate significant transfer of energy from the hanging wall to the footwall, an effect that may not be as effective when the rupture reaches the surface (is not "blind"). Transformers near the up-dip projection of the fault tip have been damaged or overturned on both the hanging-wall and footwall sides of the fault. The transfer of energy is confirmed in a numerical lattice model and could play an important role in a similar situation in Los Angeles. We suggest that the results of this study can provide important information for estimating the effects of a large thrust fault rupture in the Los Angeles basin, specially given the fact that there is so little instrumental data from large thrust fault earthquakes.

SGS Closure Methodology for Surface-layer Rough-wall Turbulence.

NASA Astrophysics Data System (ADS)

Brasseur, James G.; Juneja, Anurag

1998-11-01

As reported in another abstract, necessary under-resolution and anisotropy of integral scales near the surface in LES of rough-wall boundary layers cause errors in the statistical structure of the modeled subgrid-scale (SGS) acceleration using eddy viscosity and similarity closures. The essential difficulty is an overly strong coupling between the modeled SGS stress tensor and predicted resolved velocity u^r. Specific to this problem, we propose a class of SGS closures in which subgrid scale velocities u^s1 between an explicit filter scale Δ and the grid scale δ are estimated from the solution to a separate prognostic equation, and the SGS stress tensor is formed using u^s1 as a surrogate for subgrid velocity u^s. The method is currently under development for pseudo-spectral LES where a filter at scales δ < Δ is explicit. The exact evolution equation for u^s1 contains dynamical interactions between u^r and u^s1 which can be calculated directly, and a term which is modeled to capture energy flux from the s1 scales without altering u^s1 structure. Three levels of closure for SGS stress are possible at different levels of accuracy and computational expense. The cheapest model has been tested with DNS and LES of anisotropic buoyancy-driven turbulence. Preliminary results show major improvement in the structure of the predicted SGS acceleration with much of the spurious coupling between u^r and SGS stress removed. Performance, predictions and cost of the three levels of closure are under analysis.

Decreased proteasomal function accelerates cigarette smoke-induced pulmonary emphysema in mice.

PubMed

Yamada, Yosuke; Tomaru, Utano; Ishizu, Akihiro; Ito, Tomoki; Kiuchi, Takayuki; Ono, Ayako; Miyajima, Syota; Nagai, Katsura; Higashi, Tsunehito; Matsuno, Yoshihiro; Dosaka-Akita, Hirotoshi; Nishimura, Masaharu; Miwa, Soichi; Kasahara, Masanori

2015-06-01

Chronic obstructive pulmonary disease (COPD) is a disease common in elderly people, characterized by progressive destruction of lung parenchyma and chronic inflammation of the airways. The pathogenesis of COPD remains unclear, but recent studies suggest that oxidative stress-induced apoptosis in alveolar cells contributes to emphysematous lung destruction. The proteasome is a multicatalytic enzyme complex that plays a critical role in proteostasis by rapidly destroying misfolded and modified proteins generated by oxidative and other stresses. Proteasome activity decreases with aging in many organs including lungs, and an age-related decline in proteasomal function has been implicated in various age-related pathologies. However, the role of the proteasome system in the pathogenesis of COPD has not been investigated. Recently, we have established a transgenic (Tg) mouse model with decreased proteasomal chymotrypsin-like activity, showing age-related phenotypes. Using this model, we demonstrate here that decreased proteasomal function accelerates cigarette smoke (CS)-induced pulmonary emphysema. CS-exposed Tg mice showed remarkable airspace enlargement and increased foci of inflammation compared with wild-type controls. Importantly, apoptotic cells were found in the alveolar walls of the affected lungs. Impaired proteasomal activity also enhanced apoptosis in cigarette smoke extract (CSE)-exposed fibroblastic cells derived from mice and humans in vitro. Notably, aggresome formation and prominent nuclear translocation of apoptosis-inducing factor were observed in CSE-exposed fibroblastic cells isolated from Tg mice. Collective evidence suggests that CS exposure and impaired proteasomal activity coordinately enhance apoptotic cell death in the alveolar walls that may be involved in the development and progression of emphysema in susceptible individuals such as the elderly.

Heavy-ion induced electronic desorption of gas from metals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Molvik, A W; Kollmus, H; Mahner, E

During heavy ion operation in several particle accelerators world-wide, dynamic pressure rises of orders of magnitude were triggered by lost beam ions that bombarded the vacuum chamber walls. This ion-induced molecular desorption, observed at CERN, GSI, and BNL, can seriously limit the ion beam lifetime and intensity of the accelerator. From dedicated test stand experiments we have discovered that heavy-ion induced gas desorption scales with the electronic energy loss (dE{sub e}/d/dx) of the ions slowing down in matter; but it varies only little with the ion impact angle, unlike electronic sputtering.

Neutrons produced by known energies of ions abundant in space

NASA Technical Reports Server (NTRS)

Wadman, W. W., III

1972-01-01

Particle accelerator radiation measurements are applied to the problem of calculating biological dose from radiation produced in the walls of a spacecraft by various ions in space. Neutrons, one of the products of the interactions of energetic ions with matter, are usually quite penetrating and have large values of Q.F. or R.B.E. Ions of helium, boron, carbon, nitrogen, and oxygen were accelerated and directed onto target materials of copper or tantalum. The secondary neutron production was determined. Studies were made of the angular distribution and an inferred neutron spectrum was calculated from activities of threshold reaction detectors.

Acceleration of domain wall movement by photoirradiation in perovskite-type cobaltite

NASA Astrophysics Data System (ADS)

Okimoto, Y.; Kurashima, M.; Seko, K.; Ishikawa, T.; Onda, K.; Koshihara, S.; Kyomen, T.; Itoh, M.

2011-04-01

Femtosecond reflection spectroscopy was performed on a perovskite-type cobalt oxide, namely, Pr0.5Ca0.5CoO3, that undergoes a photoinduced spin-state transition. After photoirradiation at 30 K, the time profile of the reflectance change shows a broad peak reflecting the propagation of the photodomain (about 60 Co sites per one photon). Analysis of the peak position indicates the sudden increase of the velocity of the propagation with increasing the excitation intensity. Such acceleration with increase in fluence originates from an abrupt sound velocity change driven by a cooperative photoinduced structural transition.

Turbulent boundary layer heat transfer experiments: Convex curvature effects, including introduction and recovery

NASA Technical Reports Server (NTRS)

Simon, T. W.; Moffat, R. J.; Johnston, J. P.; Kays, W. M.

1980-01-01

Heat transfer rates were measured through turbulent and transitional boundary layers on an isothermal, convexly curved wall and downstream flat plate. The effect of convex curvature on the fully turbulent boundary layer was a reduction of the local Stanton numbers 20-50% below those predicted for a flat wall under the same circumstances. The recovery of the heat transfer rates on the downstream flat wall was extremely slow. After 60 cm of recovery length, the Stanton number was still typically 15-20% below the flat wall predicted value. Various effects important in the modeling of curved flows were studied separately. These are: (1) the effect of initial boundary layer thickness; (2) the effect of freestream velocity; (3) the effect of freestream acceleration; (4) the effect of unheated starting length; and (5) the effect of the maturity of the boundary layer. Regardless of the initial state, curvature eventually forced the boundary layer into an asymptotic curved condition. The slope, minus one, is believed to be significant.

Experimental verification of the asymtotic modal analysis method as applied to a rectangular acoustic cavity excited by structural vibration

NASA Technical Reports Server (NTRS)

Peretti, L. F.; Dowell, E. H.

1992-01-01

An experiment was performed on a rigid wall rectangular acoustic cavity driven by a flexible plate mounted in a quarter of one end wall and excited by white noise. The experiment was designed so that the assumptions of Asymptotic Modal Analysis (AMA) were satisfied for certain bandwidths and center frequencies. Measurements of sound pressure levels at points along the boundaries and incrementally into tbe interior were taken. These were compared with the theoretical results predicted with AMA, and found to be in good agreement, particularly for moderate (1/3 octave) bandwidths and sufficiently high center frequencies. Sound pressure level measurements were also taken well into the cavity interior at various points along the 5 totally rigid walls. The AMA theory, including boundary intensification effects, was shown to be accurate provided the assumption of large number of acoustic modes is satisfied, and variables such as power spectra of the wall acceleration, frequency, and damping are slowly varying in the frequency of bandwidth.

Turbulent boundary layer heat transfer experiments: Convex curvature effects including introduction and recovery

NASA Technical Reports Server (NTRS)

Simon, T. W.; Moffat, R. J.; Johnston, J. P.; Kays, W. M.

1982-01-01

Measurements were made of the heat transfer rate through turbulent and transitional boundary layers on an isothermal, convexly curved wall and downstream flat plate. The effect of convex curvature on the fully turbulent boundary layer was a reduction of the local Stanton numbers 20% to 50% below those predicted for a flat wall under the same circumstances. The recovery of the heat transfer rates on the downstream flat wall was extremely slow. After 60 cm of recovery length, the Stanton number was still typically 15% to 20% below the flat wall predicted value. Various effects important in the modeling of curved flows were studied separately. These are: the effect of initial boundary layer thickness, the effect of freestream velocity, the effect of freestream acceleration, the effect of unheated starting length, and the effect of the maturity of the boundary layer. An existing curvature prediction model was tested against this broad heat transfer data base to determine where it could appropriately be used for heat transfer predictions.

High-flux neutron source based on a liquid-lithium target

NASA Astrophysics Data System (ADS)

Halfon, S.; Feinberg, G.; Paul, M.; Arenshtam, A.; Berkovits, D.; Kijel, D.; Nagler, A.; Eliyahu, I.; Silverman, I.

2013-04-01

A prototype compact Liquid Lithium Target (LiLiT), able to constitute an accelerator-based intense neutron source, was built. The neutron source is intended for nuclear astrophysical research, boron neutron capture therapy (BNCT) in hospitals and material studies for fusion reactors. The LiLiT setup is presently being commissioned at Soreq Nuclear research Center (SNRC). The lithium target will produce neutrons through the 7Li(p,n)7Be reaction and it will overcome the major problem of removing the thermal power generated by a high-intensity proton beam, necessary for intense neutron flux for the above applications. The liquid-lithium loop of LiLiT is designed to generate a stable lithium jet at high velocity on a concave supporting wall with free surface toward the incident proton beam (up to 10 kW). During off-line tests, liquid lithium was flown through the loop and generated a stable jet at velocity higher than 5 m/s on the concave supporting wall. The target is now under extensive test program using a high-power electron-gun. Up to 2 kW electron beam was applied on the lithium flow at velocity of 4 m/s without any flow instabilities or excessive evaporation. High-intensity proton beam irradiation will take place at SARAF (Soreq Applied Research Accelerator Facility) superconducting linear accelerator currently in commissioning at SNRC.

3D Printed Scintillators For Use in Field Emission Detection and Other Nuclear Physics Experiments

NASA Astrophysics Data System (ADS)

Ficenec, Karen

2015-10-01

In accelerator cavities, field emission electrons - electrons that get stripped away from the cavity walls due to the high electromagnetic field necessary to accelerate the main beam - are partially accelerated and can crash into the cavity walls, adding to the heat-load of the cryogenic system. Because these field electrons emit gamma rays when bent by the electromagnetic field, a scintillator, if made to fit the cavity enclosure, can detect their presence. Eliminating the waste of subtractive manufacturing techniques and allowing for the production of unique, varied shapes, 3D printing of scintillators may allow for an efficient detection system. UV light is used to start a chemical polymerization process that links the monomers of the liquid resin together into larger, intertwined molecules, forming the solid structure. Each shape requires slightly different calibration of its optimal printing parameters, such as slice thickness and exposure time to UV light. Thus far, calibration parameters have been optimized for cylinders of 20 mm diameter, cones of 30 mm diameter and 30 mm height, rectangular prisms 30 by 40 by 10 mm, and square pyramids 20 mm across. Calibration continues on creating holes in the prints (for optical fibers), as well as shapes with overhangs. Scintill This work was supported in part by the National Science Foundation under Grant No. PHY-1405857.

High-flux neutron source based on a liquid-lithium target

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halfon, S.; Feinberg, G.; Paul, M.

2013-04-19

A prototype compact Liquid Lithium Target (LiLiT), able to constitute an accelerator-based intense neutron source, was built. The neutron source is intended for nuclear astrophysical research, boron neutron capture therapy (BNCT) in hospitals and material studies for fusion reactors. The LiLiT setup is presently being commissioned at Soreq Nuclear research Center (SNRC). The lithium target will produce neutrons through the {sup 7}Li(p,n){sup 7}Be reaction and it will overcome the major problem of removing the thermal power generated by a high-intensity proton beam, necessary for intense neutron flux for the above applications. The liquid-lithium loop of LiLiT is designed to generatemore » a stable lithium jet at high velocity on a concave supporting wall with free surface toward the incident proton beam (up to 10 kW). During off-line tests, liquid lithium was flown through the loop and generated a stable jet at velocity higher than 5 m/s on the concave supporting wall. The target is now under extensive test program using a high-power electron-gun. Up to 2 kW electron beam was applied on the lithium flow at velocity of 4 m/s without any flow instabilities or excessive evaporation. High-intensity proton beam irradiation will take place at SARAF (Soreq Applied Research Accelerator Facility) superconducting linear accelerator currently in commissioning at SNRC.« less

Non-invasive quantification of hemodynamics in human choriocapillaries

NASA Astrophysics Data System (ADS)

Yu, Huidan (Whitney); Chen, Rou; An, Senyou; McDonough, James; Gelfand, Bradley; Yao, Jun

2016-11-01

The development of retinal disease is inextricably linked to defects in the choroidal blood supply. However, to date a description of the hemodynamics in the human choroidal circulation is lacking. Through high resolution choroidal vascular network mapped from immunofluorescent labeling and confocal microscopy of human cadaver donor eyes. We noninvasively quantify hemodynamics including velocity, pressure, and wall-shear stress (WSS) in choriocapillaries through mesoscale modeling and GPU-accelerated fast computation. This is the first-ever map of hemodynamic parameters (WSS, pressure, and velocity) in anatomically accurate human choroidal vasculature in health and disease. The pore scale simulation results are used to evaluate porous media models with the same porosity and boundary conditions. School of Medicine, Indiana University.

Ground-Based Gas-Liquid Flow Research in Microgravity Conditions: State of Knowledge

NASA Technical Reports Server (NTRS)

McQuillen, J.; Colin, C.; Fabre, J.

1999-01-01

During the last decade, ground-based microgravity facilities have been utilized in order to obtain predictions for spacecraft system designers and further the fundamental understanding of two-phase flow. Although flow regime, pressure drop and heat transfer coefficient data has been obtained for straight tubes and a limited number of fittings, measurements of the void fraction, film thickness, wall shear stress, local velocity and void information are also required in order to develop general mechanistic models that can be utilized to ascertain the effects of fluid properties, tube geometry and acceleration levels. A review of this research is presented and includes both empirical data and mechanistic models of the flow behavior.

Online Measurement of the Energy Spread of Multi-Turn Beam in the Fermilab Booster at Injection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nelson, J.; Bhat, C. M.; Hendricks, B. S.

We have developed a computer program interfaced with the ACNET environment of Fermilab accelerators to measure energy spread of the proton beam from the LINAC at an injection into the Booster. It uses a digitizing oscilloscope and provides users an ability to configure the scope settings for optimal data acquisition from a resistive wall current monitor. When the program is launched, a) a one shot timeline is generated to initiate beam injection into the Booster, b) a gap of about 40 ns is produced in the injected beam using a set of fast kickers, c) collects line charge distribution datamore » from the wall current monitor for the first 200 μs from the injection and d) performs complete data analysis to extract full beam energy spread of the beam. The program also gives the option to store the data for offline analyses. We illustrate a case with an example. We also present results on beam energy spread as a function of beam intensity from recent measurements.« less

Fast algorithms for chiral fermions in 2 dimensions

NASA Astrophysics Data System (ADS)

Hyka (Xhako), Dafina; Osmanaj (Zeqirllari), Rudina

2018-03-01

In lattice QCD simulations the formulation of the theory in lattice should be chiral in order that symmetry breaking happens dynamically from interactions. In order to guarantee this symmetry on the lattice one uses overlap and domain wall fermions. On the other hand high computational cost of lattice QCD simulations with overlap or domain wall fermions remains a major obstacle of research in the field of elementary particles. We have developed the preconditioned GMRESR algorithm as fast inverting algorithm for chiral fermions in U(1) lattice gauge theory. In this algorithm we used the geometric multigrid idea along the extra dimension.The main result of this work is that the preconditioned GMRESR is capable to accelerate the convergence 2 to 12 times faster than the other optimal algorithms (SHUMR) for different coupling constant and lattice 32x32. Also, in this paper we tested it for larger lattice size 64x64. From the results of simulations we can see that our algorithm is faster than SHUMR. This is a very promising result that this algorithm can be adapted also in 4 dimension.

Evaluation of marginal gap of Ni-Cr copings made with conventional and accelerated casting techniques.

PubMed

Tannamala, Pavan Kumar; Azhagarasan, Nagarasampatti Sivaprakasam; Shankar, K Chitra

2013-01-01

Conventional casting techniques following the manufacturers' recommendations are time consuming. Accelerated casting techniques have been reported, but their accuracy with base metal alloys has not been adequately studied. We measured the vertical marginal gap of nickel-chromium copings made by conventional and accelerated casting techniques and determined the clinical acceptability of the cast copings in this study. Experimental design, in vitro study, lab settings. Ten copings each were cast by conventional and accelerated casting techniques. All copings were identical, only their mold preparation schedules differed. Microscopic measurements were recorded at ×80 magnification on the perpendicular to the axial wall at four predetermined sites. The marginal gap values were evaluated by paired t test. The mean marginal gap by conventional technique (34.02 μm) is approximately 10 μm lesser than that of accelerated casting technique (44.62 μm). As the P value is less than 0.0001, there is highly significant difference between the two techniques with regard to vertical marginal gap. The accelerated casting technique is time saving and the marginal gap measured was within the clinically acceptable limits and could be an alternative to time-consuming conventional techniques.

Shielding analyses for repetitive high energy pulsed power accelerators

NASA Astrophysics Data System (ADS)

Jow, H. N.; Rao, D. V.

Sandia National Laboratories (SNL) designs, tests and operates a variety of accelerators that generate large amounts of high energy Bremsstrahlung radiation over an extended time. Typically, groups of similar accelerators are housed in a large building that is inaccessible to the general public. To facilitate independent operation of each accelerator, test cells are constructed around each accelerator to shield it from the radiation workers occupying surrounding test cells and work-areas. These test cells, about 9 ft. high, are constructed of high density concrete block walls that provide direct radiation shielding. Above the target areas (radiation sources), lead or steel plates are used to minimize skyshine radiation. Space, accessibility and cost considerations impose certain restrictions on the design of these test cells. SNL Health Physics division is tasked to evaluate the adequacy of each test cell design and compare resultant dose rates with the design criteria stated in DOE Order 5480.11. In response, SNL Health Physics has undertaken an intensive effort to assess existing radiation shielding codes and compare their predictions against measured dose rates. This paper provides a summary of the effort and its results.

X-ray driven channeling acceleration in crystals and carbon nanotubes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shin, Young-Min; Still, Dean A.; Shiltsev, Vladimir

2013-12-01

Acceleration of particles channeling in a crystal by means of diffracted x-rays via Bormann anomalous transmission was conceived for heavy ions and muons by Tajima and Cavenago [Phys. Rev. Lett. 59, 1440 (1987)], which potentially offers an appreciably high field gradient on the order of GV/cm. The theoretical model of the high gradient acceleration has been studied in two kinds of atomic structure, crystals and carbon nanotubes (CNTs), with analytic calculations and electromagnetic eigenmode simulations. A range of acceleration gradients and cutoffs of the x-ray power (the lowest power limit to overcome the Bremsstrahlung radiation losses) are characterized in termsmore » of the lattice constants, unit cell sizes, and photon energies. The parametric analysis indicates that the required x-ray power can be reduced to an order of megawatt by replacing crystals with CNTs. Eventually, the equivalent dielectric approximation of a multi-wall nanotube shows that 250–810 MeV muons can be synchronously coupled with x-rays of 0.65–1.32 keV in the accelerating structure.« less

Liquid-phase penetration under unsteady in-cylinder conditions: Soy- and Cuphea-derived biodiesel fuels vs. conventional diesel

USDA-ARS?s Scientific Manuscript database

Accelerated dilution of engine-lubrication oil is a significant potential issue when fueling with biodiesel. Biodiesel produced from some feedstocks is less volatile than conventional diesel, which makes wall-impingement of liquid fuel more likely, a problem that could be exacerbated by advanced in...

Lorentz force detuning analysis of the Spallation Neutron Source (SNS) accelerating cavities.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mitchell, R.R.; Matsumoto, K. Y.; Ciovati, G.

2001-01-01

The Spallation Neutron Source (SNS) project incorporates a superconducting radio-frequency (SRF) accelerator for the final section of the pulsed mode linac. Cavities with geometrical {beta} values of {beta}=0.61 and {beta}=0.81 are utilized in the SRF section, and are constructed out of thin-walled niobium with stiffener rings welded between the cells near the iris. The welded titanium helium vessel and tuner assembly restrains the cavity beam tubes. Cavities with {beta} values less than one have relatively steep and flat side-walls making the cavities susceptible to Lorentz force detuning. In addition, the pulsed RF induces cyclic Lorentz pressures that mechanically excite themore » cavities, producing a dynamic Lorentz force detuning different from a continuous RF system. The amplitude of the dynamic detuning for a given cavity design is a function of the mechanical damping, stiffness of the tuner/helium vessel assembly, RF pulse profile, and the RF pulse rate. This paper presents analysis and testing results to date, and indicates areas where more investigation is required.« less

Effect of plasma distribution on propulsion performance in electrodeless plasma thrusters

NASA Astrophysics Data System (ADS)

Takao, Yoshinori; Takase, Kazuki; Takahashi, Kazunori

2016-09-01

A helicon plasma thruster consisting of a helicon plasma source and a magnetic nozzle is one of the candidates for long-lifetime thrusters because no electrodes are employed to generate or accelerate plasma. A recent experiment, however, detected the non-negligible axial momentum lost to the lateral wall boundary, which degrades thruster performance, when the source was operated with highly ionized gases. To investigate this mechanism, we have conducted two-dimensional axisymmetric particle-in-cell (PIC) simulations with the neutral distribution obtained by Direct Simulation Monte Carlo (DSMC) method. The numerical results have indicated that the axially asymmetric profiles of the plasma density and potential are obtained when the strong decay of neutrals occurs at the source downstream. This asymmetric potential profile leads to the accelerated ion towards the lateral wall, leading to the non-negligible net axial force in the opposite direction of the thrust. Hence, to reduce this asymmetric profile by increasing the neutral density at downstream and/or by confining plasma with external magnetic field would result in improvement of the propulsion performance. These effects are also analyzed by PIC/DSMC simulations.

Channeling technique to make nanoscale ion beams

NASA Astrophysics Data System (ADS)

Biryukov, V. M.; Bellucci, S.; Guidi, V.

2005-04-01

Particle channeling in a bent crystal lattice has led to an efficient instrument for beam steering at accelerators [Biryukov et al., Crystal Channeling and its Application at High Energy Accelerators, Springer, Berlin, 1997], demonstrated from MeV to TeV energies. In particular, crystal focusing of high-energy protons to micron size has been demonstrated at IHEP with the results well in match with Lindhard (critical angle) prediction. Channeling in crystal microstructures has been proposed as a unique source of a microbeam of high-energy particles [Bellucci et al., Phys. Rev. ST Accel. Beams 6 (2003) 033502]. Channeling in nanostructures (single-wall and multi-wall nanotubes) offers the opportunities to produce ion beams on nanoscale. Particles channeled in a nanotube (with typical diameter of about 1 nm) are trapped in two dimensions and can be steered (deflected, focused) with the efficiency similar to that of crystal channeling or better. This technique has been a subject of computer simulations, with experimental efforts under way in several high-energy labs, including IHEP. We present the theoretical outlook for making channeling-based nanoscale ion beams and report the experience with crystal-focused microscale proton beams.

Pipe degradation investigations for optimization of flow-accelerated corrosion inspection location selection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chandra, S.; Habicht, P.; Chexal, B.

1995-12-01

A large amount of piping in a typical nuclear power plant is susceptible to Flow-Accelerated Corrosion (FAC) wall thinning to varying degrees. A typical PAC monitoring program includes the wall thickness measurement of a select number of components in order to judge the structural integrity of entire systems. In order to appropriately allocate resources and maintain an adequate FAC program, it is necessary to optimize the selection of components for inspection by focusing on those components which provide the best indication of system susceptibility to FAC. A better understanding of system FAC predictability and the types of FAC damage encounteredmore » can provide some of the insight needed to better focus and optimize the inspection plan for an upcoming refueling outage. Laboratory examination of FAC damaged components removed from service at Northeast Utilities` (NU) nuclear power plants provides a better understanding of the damage mechanisms involved and contributing causes. Selected results of this ongoing study are presented with specific conclusions which will help NU to better focus inspections and thus optimize the ongoing FAC inspection program.« less

A nanoscale perspective on the effects of transverse microprestress on drying creep of nanoporous solids

NASA Astrophysics Data System (ADS)

Sinko, Robert; Bažant, Zdeněk P.; Keten, Sinan

2018-01-01

The Pickett effect describes the excess non-additive strain developed during drying of a nanoporous solid material under creep. One explanation for its origins, developed using micromechanical models, is the progressive relaxation of internally developed microprestress. However, these models have not explicitly considered the effects of this microprestress on nanoscale energy barriers that govern the relative motion and displacement between nanopore walls during deformation. Here, we evaluate the nanoscale effects of transverse microprestresses on the drying creep behaviour of a nanoscale slit pore using coarse-grained molecular dynamics. We find that the underlying energy barrier depends exponentially on the transverse microprestress, which is attributed to changes in the effective viscosity and degree of nanoconfinement of molecules in the water interlayer. Specifically, as the transverse microprestress is relaxed (i.e. its magnitude decreases), the activation energy barrier is reduced, thereby leading to an acceleration of the creep behaviour and a stronger Pickett effect. Based on our simulation results, we introduce a new microprestress-dependent energy term into our existing Arrhenius model, which describes the relative displacement of pore walls as a function of the underlying activation energy barriers. Our findings further verify the existing micromechanical theories for the origin of the Pickett effect and establish a quantitative relationship between the transverse microprestress and the intensity of the Pickett effect.

Critical point wetting drop tower experiment

NASA Technical Reports Server (NTRS)

Kaukler, William F.

1990-01-01

The 100 m Drop Tower at NASA-Marshall was used to provide the step change in acceleration from 1.0 to 0.0005 g. An inter-fluid meniscus oscillates vertically within a cylindrical container when suddenly released from earth's gravity and taken into a microgravity environment. Oscillations damp out from energy dissipative mechanisms such as viscosity and interfacial friction. Damping of the oscillations by the later mechanism is affected by the nature of the interfacial junction between the fluid-fluid interface and the container wall. In earlier stages of the project, the meniscus shape which developed during microgravity conditions was applied to evaluations of wetting phenomena near the critical temperature. Variations in equilibrium contact angle against the container wall were expected to occur under critical wetting conditions. However, it became apparent that the meaningful phenomenon was the damping of interfacial oscillations. This latter concept makes up the bulk of this report. Perfluoromethyl cyclohexane and isopropanol in glass were the materials used for the experiment. The wetting condition of the fluids against the wall changes at the critical wetting transition temperature. This change in wetting causes a change in the damping characteristics of the interfacial excursions during oscillation and no measurable change in contact angle. The effect of contact line friction measured above and below the wetting transition temperature was to increase the period of vertical oscillation for the vapor-liquid interface when below the wetting transition temperature.

Shake-table testing of a self-centering precast reinforced concrete frame with shear walls

NASA Astrophysics Data System (ADS)

Lu, Xilin; Yang, Boya; Zhao, Bin

2018-04-01

The seismic performance of a self-centering precast reinforced concrete (RC) frame with shear walls was investigated in this paper. The lateral force resistance was provided by self-centering precast RC shear walls (SPCW), which utilize a combination of unbonded prestressed post-tensioned (PT) tendons and mild steel reinforcing bars for flexural resistance across base joints. The structures concentrated deformations at the bottom joints and the unbonded PT tendons provided the self-centering restoring force. A 1/3-scale model of a five-story self-centering RC frame with shear walls was designed and tested on a shake-table under a series of bi-directional earthquake excitations with increasing intensity. The acceleration response, roof displacement, inter-story drifts, residual drifts, shear force ratios, hysteresis curves, and local behaviour of the test specimen were analysed and evaluated. The results demonstrated that seismic performance of the test specimen was satisfactory in the plane of the shear wall; however, the structure sustained inter-story drift levels up to 2.45%. Negligible residual drifts were recorded after all applied earthquake excitations. Based on the shake-table test results, it is feasible to apply and popularize a self-centering precast RC frame with shear walls as a structural system in seismic regions.

Spin-orbit-torque-induced magnetic domain wall motion in Ta/CoFe nanowires with sloped perpendicular magnetic anisotropy.

PubMed

Zhang, Yue; Luo, Shijiang; Yang, Xiaofei; Yang, Chang

2017-05-17

In materials with the gradient of magnetic anisotropy, spin-orbit-torque-induced magnetization behaviour has attracted attention because of its intriguing scientific principle and potential application. Most of the magnetization behaviours microscopically originate from magnetic domain wall motion, which can be precisely depicted using the standard cooperative coordinate method (CCM). However, the domain wall motion in materials with the gradient of magnetic anisotropy using the CCM remains lack of investigation. In this paper, by adopting CCM, we established a set of equations to quantitatively depict the spin-orbit-torque-induced motion of domain walls in a Ta/CoFe nanotrack with weak Dzyaloshinskii-Moriya interaction and magnetic anisotropy gradient. The equations were solved numerically, and the solutions are similar to those of a micromagnetic simulation. The results indicate that the enhanced anisotropy along the track acts as a barrier to inhibit the motion of the domain wall. In contrast, the domain wall can be pushed to move in a direction with reduced anisotropy, with the velocity being accelerated by more than twice compared with that for the constant anisotropy case. This substantial velocity manipulation by anisotropy engineering is important in designing novel magnetic information devices with high reading speeds.

Geometric effects resulting from the asymmetry of dipping fault: Hanging wall/ footwall effects

NASA Astrophysics Data System (ADS)

Wang, Dong; Xie, Li-Li; Hu, Jin-Jun

2008-05-01

Root-mean-square distance D rms with characteristic of weighted-average is introduced in this article firstly. D rms can be used to capture the general proximity of a site to a dipping fault plane comparing with the rupture distance D rup and the seismogenic distance D seis. Then, using D rup, D seis and D rms, the hanging wall/footwall effects on the peak ground acceleration (PGA) during the 1999 Chi-Chi earthquake are evaluated by regression analysis. The logarithm residual shows that the PGA on hanging wall is much greater than that on footwall at the same D rup or D seis when the D rup or D seis is used as site-to-source distance measure. In contrast, there is no significant difference between the PGA on hanging wall and that on footwall at the same D rms when D rms is used. This result confirms that the hanging wall/footwall effect is mainly a geometric effect caused by the asymmetry of dipping fault. Therefore, the hanging wall/footwall effect on the near-fault ground motions can be ignored in the future attenuation analysis if the root-mean-square distance D rms is used as the site-to-source distance measure.

Effect of Random Thermal Spikes on Stirling Convertor Heater Head Reliability

NASA Technical Reports Server (NTRS)

Shah, Ashwin R.; Korovaichuk, Igor; Halford, Gary R.

2004-01-01

Onboard radioisotope power systems being developed to support future NASA exploration missions require reliable design lifetimes of up to 14 yr and beyond. The structurally critical heater head of the high-efficiency developmental Stirling power convertor has undergone extensive computational analysis of operating temperatures (up to 650 C), stresses, and creep resistance of the thin-walled Inconel 718 bill of material. Additionally, assessment of the effect of uncertainties in the creep behavior of the thin-walled heater head, the variation in the manufactured thickness, variation in control temperature, and variation in pressure on the durability and reliability were performed. However, it is possible for the heater head to experience rare incidences of random temperature spikes (excursions) of short duration. These incidences could occur randomly with random magnitude and duration during the desired mission life. These rare incidences could affect the creep strain rate and therefore the life. The paper accounts for these uncertainties and includes the effect of such rare incidences, random in nature, on the reliability. The sensitivities of variables affecting the reliability are quantified and guidelines developed to improve the reliability are outlined. Furthermore, the quantified reliability is being verified with test data from the accelerated benchmark tests being conducted at the NASA Glenn Research Center.

Reliability-Based Life Assessment of Stirling Convertor Heater Head

NASA Technical Reports Server (NTRS)

Shah, Ashwin R.; Halford, Gary R.; Korovaichuk, Igor

2004-01-01

Onboard radioisotope power systems being developed and planned for NASA's deep-space missions require reliable design lifetimes of up to 14 yr. The structurally critical heater head of the high-efficiency Stirling power convertor has undergone extensive computational analysis of operating temperatures, stresses, and creep resistance of the thin-walled Inconel 718 bill of material. A preliminary assessment of the effect of uncertainties in the material behavior was also performed. Creep failure resistance of the thin-walled heater head could show variation due to small deviations in the manufactured thickness and in uncertainties in operating temperature and pressure. Durability prediction and reliability of the heater head are affected by these deviations from nominal design conditions. Therefore, it is important to include the effects of these uncertainties in predicting the probability of survival of the heater head under mission loads. Furthermore, it may be possible for the heater head to experience rare incidences of small temperature excursions of short duration. These rare incidences would affect the creep strain rate and, therefore, the life. This paper addresses the effects of such rare incidences on the reliability. In addition, the sensitivities of variables affecting the reliability are quantified, and guidelines developed to improve the reliability are outlined. Heater head reliability is being quantified with data from NASA Glenn Research Center's accelerated benchmark testing program.

A Rabbit Model for Testing Helper-Dependent Adenovirus-Mediated Gene Therapy for Vein Graft Atherosclerosis.

PubMed

Bi, Lianxiang; Wacker, Bradley K; Bueren, Emma; Ham, Ervin; Dronadula, Nagadhara; Dichek, David A

2017-12-15

Coronary artery bypass vein grafts are a mainstay of therapy for human atherosclerosis. Unfortunately, the long-term patency of vein grafts is limited by accelerated atherosclerosis. Gene therapy, directed at the vein graft wall, is a promising approach for preventing vein graft atherosclerosis. Because helper-dependent adenovirus (HDAd) efficiently transduces grafted veins and confers long-term transgene expression, HDAd is an excellent candidate for delivery of vein graft-targeted gene therapy. We developed a model of vein graft atherosclerosis in fat-fed rabbits and demonstrated long-term (≥20 weeks) persistence of HDAd genomes after graft transduction. This model enables quantitation of vein graft hemodynamics, wall structure, lipid accumulation, cellularity, vector persistence, and inflammatory markers on a single graft. Time-course experiments identified 12 weeks after transduction as an optimal time to measure efficacy of gene therapy on the critical variables of lipid and macrophage accumulation. We also used chow-fed rabbits to test whether HDAd infusion in vein grafts promotes intimal growth and inflammation. HDAd did not increase intimal growth, but had moderate-yet significant-pro-inflammatory effects. The vein graft atherosclerosis model will be useful for testing HDAd-mediated gene therapy; however, pro-inflammatory effects of HdAd remain a concern in developing HDAd as a therapy for vein graft disease.

Single bunch transverse instability in a circular accelerator with chromaticity and space charge

DOE PAGES

Balbekov, V.

2015-10-21

The transverse instability of a bunch in a circular accelerator is elaborated in this paper. A new tree-modes model is proposed and developed to describe the most unstable modes of the bunch. This simple and flexible model includes chromaticity and space charge, and can be used with any bunch and wake forms. The dispersion equation for the bunch eigentunes is obtained in form of a third-order algebraic equation. The known head-tail and TMCI modes appear as the limiting cases which are distinctly bounded at zero chromaticity only. It is shown that the instability parameters depend only slightly on the bunchmore » model but they are rather sensitive to the wake shape. In particular, space charge effects are investigated in the paper and it is shown that their influence depends on sign of wake field enhancing the bunch stability if the wake is negative. In addition, the resistive wall wake is considered in detail including a comparison of single and collective effects. A comparison of the results with earlier publications is carried out.« less

Application of the NEXT Ion Thruster Lifetime Assessment to Thruster Throttling

NASA Technical Reports Server (NTRS)

VanNoord, Jonathan L.; Herman, Daniel A.

2010-01-01

Ion thrusters are low thrust, high specific impulse devices with typical operational lifetimes of 10,000 to 30,000 hr over a range of throttling conditions. The NEXT ion thruster is the latest generation of ion thrusters under development. The NEXT ion thruster currently has a qualification level propellant throughput requirement of 450 kg of xenon, which corresponds to roughly 22,000 hr of operation at the highest input power throttling point. This paper will provide a brief review the previous life assessment predictions for various throttling conditions. A further assessment will be presented examining the anticipated accelerator grid hole wall erosion and related electron backstreaming limit. The continued assessment of the NEXT ion thruster indicates that the first failure mode across the throttling range is expected to be in excess of 36,000 hr of operation from charge exchange induced groove erosion. It is at this duration that the groove is predicted to penetrate the accelerator grid possibly resulting in structural failure. Based on these lifetime and mission assessments, a throttling approach is presented for the Long Duration Test to demonstrate NEXT thruster lifetime and validate modeling.

Disentangling the role of athermal walls on the Knudsen paradox in molecular and granular gases

NASA Astrophysics Data System (ADS)

Gupta, Ronak; Alam, Meheboob

2018-01-01

The nature of particle-wall interactions is shown to have a profound impact on the well-known "Knudsen paradox" [or the "Knudsen minimum" effect, which refers to the decrease of the mass-flow rate of a gas with increasing Knudsen number Kn, reaching a minimum at Kn˜O (1 ) and increasing logarithmically with Kn as Kn→∞ ] in the acceleration-driven Poiseuille flow of rarefied gases. The nonmonotonic variation of the flow rate with Kn occurs even in a granular or dissipative gas in contact with thermal walls. The latter result is in contradiction with recent work [Alam et al., J. Fluid Mech. 782, 99 (2015), 10.1017/jfm.2015.523] that revealed the absence of the Knudsen minimum in granular Poiseuille flow for which the flow rate was found to decrease at large values of Kn. The above conundrum is resolved by distinguishing between "thermal" and "athermal" walls, and it is shown that, for both molecular and granular gases, the momentum transfer to athermal walls is much different than that to thermal walls which is directly responsible for the anomalous flow-rate variation with Kn in the rarefied regime. In the continuum limit of Kn→0 , the athermal walls are shown to be closely related to "no-flux" ("adiabatic") walls for which the Knudsen minimum does not exist either. A possible characterization of athermal walls in terms of (1) an effective specularity coefficient for the slip velocity and (2) a flux-type boundary condition for granular temperature is suggested based on simulation results.

A turbulence model for pulsatile arterial flows.

PubMed

Younis, B A; Berger, S A

2004-10-01

Difficulties in predicting the behavior of some high Reynolds number flows in the circulatory system stem in part from the severe requirements placed on the turbulence model chosen to close the time-averaged equations of fluid motion. In particular, the successful turbulence model is required to (a) correctly capture the "nonequilibrium" effects wrought by the interactions of the organized mean-flow unsteadiness with the random turbulence, (b) correctly reproduce the effects of the laminar-turbulent transitional behavior that occurs at various phases of the cardiac cycle, and (c) yield good predictions of the near-wall flow behavior in conditions where the universal logarithmic law of the wall is known to be not valid. These requirements are not immediately met by standard models of turbulence that have been developed largely with reference to data from steady, fully turbulent flows in approximate local equilibrium. The purpose of this paper is to report on the development of a turbulence model suited for use in arterial flows. The model is of the two-equation eddy-viscosity variety with dependent variables that are zero-valued at a solid wall and vary linearly with distance from it. The effects of transition are introduced by coupling this model to the local value of the intermittency and obtaining the latter from the solution of a modeled transport equation. Comparisons with measurements obtained in oscillatory transitional flows in circular tubes show that the model produces substantial improvements over existing closures. Further pulsatile-flow predictions, driven by a mean-flow wave form obtained in a diseased human carotid artery, indicate that the intermittency-modified model yields much reduced levels of wall shear stress compared to the original, unmodified model. This result, which is attributed to the rapid growth in the thickness of the viscous sublayer arising from the severe acceleration of systole, argues in favor of the use of the model for the prediction of arterial flows.

Twin-Screw Extruder Development for the ITER Pellet Injection System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meitner, Steven J; Baylor, Larry R; Combs, Stephen Kirk

The ITER pellet injection system is comprised of devices to form and accelerate pellets, and will be connected to inner wall guide tubes for fueling, and outer wall guide tubes for ELM pacing. An extruder will provide a stream of solid hydrogen isotopes to a secondary section, where pellets are cut and accelerated with a gas gun into the plasma. The ITER pellet injection system is required to provide a plasma fueling rate of 120 Pa-m3/s (900 mbar-L/s) and durations of up to 3000 s. The fueling pellets will be injected at a rate up to 10 Hz and pelletsmore » used to trigger ELMs will be injected at higher rates up to 20 Hz. A twin-screw extruder for the ITER pellet injection system is under development at the Oak Ridge National Laboratory. A one-fifth ITER scale prototype has been built and has demonstrated the production of a continuous solid deuterium extrusion. The 27 mm diameter, intermeshed, counter-rotating extruder screws are rotated at a rate up to ≈5 rpm. Deuterium gas is pre-cooled and liquefied and solidified in separate extruder barrels. The precooler consists of a deuterium gas filled copper coil suspended in a separate stainless steel vessel containing liquid nitrogen. The liquefier is comprised of a copper barrel connected to a Cryomech AL330 cryocooler, which has a machined helical groove surrounded by a copper jacket, through which the pre-cooled deuterium condenses. The lower extruder barrel is connected to a Cryomech GB-37 cryocooler to solidify the deuterium (at ≈15 K) before it is forced through the extruder die. The die forms the extrusion to a 3 mm x 4 mm rectangular cross section. Design improvements have been made to improve the pre-cooler and liquefier heat exchangers, to limit the loss of extrusion through gaps in the screws. This paper will describe the design improvements for the next iteration of the extruder prototype.« less

Control of Mechanical Stresses of High Pressure Container Walls by Magnetoelastic Method

NASA Astrophysics Data System (ADS)

Kulak, S. M.; Novikov, V. F.; Baranov, A. V.

2016-10-01

Deformations of the walls of pressure vessels arising in the process of testing and operation, as well as reduce their thickness due to corrosion, to create the prerequisites for the growth of mechanical stresses which accelerating the processes of strain aging, embrittlement of the material and reducing its fatigue properties. This article is devoted to researches of the magnetoelastic demagnetization in the wall of steel vessel of loading by internal pressure. It is established that the increasing pressure on the vessel wall is accompanied by a monotonic decrease in the intensity of the magnetic stray field of local magnetization of steel. It is shown that a magnetic stray field of local magnetization of the wall of steel vessel is non-uniform due to differences in structure and stresses. It is proposed to use the obtained results to control the stress state of vessels, experiencing multi-axial loads generated by internal pressure (pipelines, oil tanks, etc.) The method of magnetoelastic of the demagnetization of the steel has a high sensitivity to mechanical stress, the simplicity of implementation and expressiveness compared to the strain gauge and method of coercive force.

Droplet and multiphase effects in a shock-driven hydrodynamic instability with reshock

NASA Astrophysics Data System (ADS)

Middlebrooks, John B.; Avgoustopoulos, Constantine G.; Black, Wolfgang J.; Allen, Roy C.; McFarland, Jacob A.

2018-06-01

Shock-driven multiphase instabilities (SDMI) are unique physical phenomena that have far-reaching applications in engineering and science such as high energy explosions, scramjet combustors, and supernovae events. The SDMI arises when a multiphase field is impulsively accelerated by a shock wave and evolves as a result of gradients in particle-gas momentum transfer. A new shock tube facility has been constructed to study the SDMI. Experiments were conducted to investigate liquid particle and multiphase effects in the SDMI. A multiphase cylindrical interface was created with water droplet laden air in our horizontal shock tube facility. The interface was accelerated by a Mach 1.66 shock wave, and its reflection from the end wall. The interface development was captured using laser illumination and a high-resolution CCD camera. Laser interferometry was used to determine the droplet size distribution. A particle filtration technique was used to determine mass loading within an interface and verify particle size distribution. The effects of particle number density, particle size, and a secondary acceleration (reshock) of the interface were noted. Particle number density effects were found comparable to Atwood number effects in the Richtmyer-Meshkov instability for small (˜ 1.7 {μ }m) droplets. Evaporation was observed to alter droplet sizes and number density, markedly after reshock. For large diameter droplets (˜ 10.7 {μ }m), diminished development was observed with larger droplets lagging far behind the interface. These lagging droplets were also observed to breakup after reshock into structured clusters of smaller droplets. Mixing width values were reported to quantify mixing effects seen in images.

Ion source development for a photoneutralization based NBI system for fusion reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simonin, A.; Esch, H. P. L. de; Garibaldi, P.

2015-04-08

The next step after ITER is to demonstrate the viability and generation of electricity by a future fusion reactor (DEMO). The specifications required to operate an NBI system on DEMO are very demanding. The system has to provide a very high level of power and energy, ~100MW of D° beam at 1MeV, including high wall-plug efficiency (η > 60%). For this purpose, a new injector concept, called Siphore, is under investigation between CEA and French universities. Siphore is based on the stripping of the accelerated negative ions by photo-detachment provided by several Fabry-Perot cavities (3.5MW of light power per cavity)more » implemented along the D{sup −} beam. The beamline is designed to be tall and narrow in order that the photon flux overlaps the entire negative ion beam. The paper will describe the present R and D at CEA which addresses the development of an ion source and pre-accelerator prototypes for Siphore, the main goal being to produce an intense negative ion beam sheet. The negative ion source Cybele is based on a magnetized plasma column where hot electrons are emitted from the source center. Parametric studies of the source are performed using Langmuir probes in order to characterize the plasma and to compare with numerical models being developed in French universities.« less

Program and charts for determining shock tube, and expansion tunnel flow quantities for real air

NASA Technical Reports Server (NTRS)

Miller, C. G., III; Wilder, S. E.

1975-01-01

A computer program in FORTRAN 4 language was written to determine shock tube, expansion tube, and expansion tunnel flow quantities for real-air test gas. This program permits, as input data, a number of possible combinations of flow quantities generally measured during a test. The versatility of the program is enhanced by the inclusion of such effects as a standing or totally reflected shock at the secondary diaphragm, thermochemical-equilibrium flow expansion and frozen flow expansion for the expansion tube and expansion tunnel, attenuation of the flow in traversing the acceleration section of the expansion tube, real air as the acceleration gas, and the effect of wall boundary layer on the acceleration section air flow. Charts which provide a rapid estimation of expansion tube performance prior to a test are included.

Ultrasonics and space instrumentation

NASA Technical Reports Server (NTRS)

1987-01-01

The design topic selected was an outgrowth of the experimental design work done in the Fluid Behavior in Space experiment, which relies on the measurement of minute changes of the pressure and temperature to obtain reasonably accurate volume determinations. An alternative method of volume determination is the use of ultrasonic imaging. An ultrasonic wave system is generated by wall mounted transducer arrays. The interior liquid configuration causes reflection and refraction of the pattern so that analysis of the received wave system provides a description of the configuration and hence volume. Both continuous and chirp probe beams were used in a laboratory experiment simulating a surface wetting propellant. The hardware included a simulated tank with gaseous voids, transmitting and receiving transducers, transmitters, receivers, computer interface, and computer. Analysis software was developed for image generation and interpretation of results. Space instrumentation was pursued in support of a number of experiments under development for GAS flights. The program included thirty undergraduate students pursuing major qualifying project work under the guidance of eight faculty supported by a teaching assistant. Both mechanical and electrical engineering students designed and built several microprocessor systems to measure parameters such as temperature, acceleration, pressure, velocity, and circulation in order to determine combustion products, vortex formation, gas entrainment, EMR emissions from thunderstorms, and milli-g-accelerations due to crew motions.

Accelerated horizons and Planck-scale kinematics

NASA Astrophysics Data System (ADS)

Arzano, Michele; Laudonio, Matteo

2018-04-01

We extend the concept of accelerated horizons to the framework of deformed relativistic kinematics at the Planck scale. We show that the nontrivial effects due to symmetry deformation manifest in a finite blueshift for field modes as measured by a Rindler observer approaching the horizon. We investigate whether, at a field theoretic level, this effect could manifest in the possibility of a finite horizon contribution to the entropy, a sort of covariant brick wall. In the specific model of symmetry deformation considered, it will turn out that a nondiverging density of modes close to the horizon can be achieved only by introducing a momentum space measure which violates Lorentz invariance.

Accelerated idioventricular rhythm requiring catheter ablation in a child: The dark side of a benign arrhythmia.

PubMed

Errahmouni, A; Bun, S-S; Latcu, D G; Tazi-Mezalek, A; Saoudi, N

2017-11-01

A 12 year-old boy, with no history of cardiac disease, was referred to our department for evaluation of an incessant accelerated idioventricular rhythm (AIVR) complicated with severe left ventricular (LV) dysfunction and cardiogenic shock. Extensive diagnostic work-up failed to reveal any structural heart disease. During electrophysiological study, AIVR originated from the right ventricular endocardial anterior wall and was successfully ablated using remote magnetic navigation. LV function showed complete recovery four weeks after the procedure. This case highlights a life-threatening evolution of an arrhythmia generally presented as a benign entity in children. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Charged particle beam scanning using deformed high gradient insulator

DOEpatents

Chen, Yu -Jiuan

2015-10-06

Devices and methods are provided to allow rapid deflection of a charged particle beam. The disclosed devices can, for example, be used as part of a hadron therapy system to allow scanning of a target area within a patient's body. The disclosed charged particle beam deflectors include a dielectric wall accelerator (DWA) with a hollow center and a dielectric wall that is substantially parallel to a z-axis that runs through the hollow center. The dielectric wall includes one or more deformed high gradient insulators (HGIs) that are configured to produce an electric field with an component in a direction perpendicular to the z-axis. A control component is also provided to establish the electric field component in the direction perpendicular to the z-axis and to control deflection of a charged particle beam in the direction perpendicular to the z-axis as the charged particle beam travels through the hollow center of the DWA.

Red Sky with Red Mesa

ScienceCinema

None

2018-01-16

The Red Sky/Red Mesa supercomputing platform dramatically reduces the time required to simulate complex fuel models, from 4-6 months to just 4 weeks, allowing researchers to accelerate the pace at which they can address these complex problems. Its speed also reduces the need for laboratory and field testing, allowing for energy reduction far beyond data center walls.

33 CFR 208.10 - Local flood protection works; maintenance and operation of structures and facilities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... the levee and to repair the damaged section. (c) Flood walls—(1) Maintenance. Periodic inspections... accelerated seepage paths; (iv) The concrete has not undergone cracking, chipping, or breaking to an extent... that no fires are being built near them; (vii) No bank caving conditions exist riverward of the wall...

33 CFR 208.10 - Local flood protection works; maintenance and operation of structures and facilities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the levee and to repair the damaged section. (c) Flood walls—(1) Maintenance. Periodic inspections... accelerated seepage paths; (iv) The concrete has not undergone cracking, chipping, or breaking to an extent... that no fires are being built near them; (vii) No bank caving conditions exist riverward of the wall...

33 CFR 208.10 - Local flood protection works; maintenance and operation of structures and facilities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... the levee and to repair the damaged section. (c) Flood walls—(1) Maintenance. Periodic inspections... accelerated seepage paths; (iv) The concrete has not undergone cracking, chipping, or breaking to an extent... that no fires are being built near them; (vii) No bank caving conditions exist riverward of the wall...

Density profiles in the Scrape-Off Layer interpreted through filament dynamics

NASA Astrophysics Data System (ADS)

Militello, Fulvio

2017-10-01

We developed a new theoretical framework to clarify the relation between radial Scrape-Off Layer density profiles and the fluctuations that generate them. The framework provides an interpretation of the experimental features of the profiles and of the turbulence statistics on the basis of simple properties of the filaments, such as their radial motion and their draining towards the divertor. L-mode and inter-ELM filaments are described as a Poisson process in which each event is independent and modelled with a wave function of amplitude and width statistically distributed according to experimental observations and evolving according to fluid equations. We will rigorously show that radially accelerating filaments, less efficient parallel exhaust and also a statistical distribution of their radial velocity can contribute to induce flatter profiles in the far SOL and therefore enhance plasma-wall interactions. A quite general result of our analysis is the resiliency of this non-exponential nature of the profiles and the increase of the relative fluctuation amplitude towards the wall, as experimentally observed. According to the framework, profile broadening at high fueling rates can be caused by interactions with neutrals (e.g. charge exchange) in the divertor or by a significant radial acceleration of the filaments. The framework assumptions were tested with 3D numerical simulations of seeded SOL filaments based on a two fluid model. In particular, filaments interact through the electrostatic field they generate only when they are in close proximity (separation comparable to their width in the drift plane), thus justifying our independence hypothesis. In addition, we will discuss how isolated filament motion responds to variations in the plasma conditions, and specifically divertor conditions. Finally, using the theoretical framework we will reproduce and interpret experimental results obtained on JET, MAST and HL-2A.

Is Beta-Amyloid Accumulation a Cause or Consequence of Alzheimer’s Disease?

PubMed Central

Wang, Shaoxun; Mims, Paige N.; Roman, Richard J.; Fan, Fan

2017-01-01

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that is characterized by the pathological hallmarks of extracellular beta-amyloid (Aβ) plaques and intraneuronal tau-containing neurofibrillary tangles in the brain. Intraneuronal accumulation of Aβ also plays a role to accelerate AD progression by promoting neurodegeneration. Additionally, AD is associated with the development of amyloid angiopathy (CAA), in which Aβ builds up on the walls of the cerebral arteries, which augments the development of cerebral vascular disease (CVD). Conversely, CVD promotes Aβ deposition and the development of AD by affecting the balance of Aβ production and clearance. However, it remains to be determined whether the accumulation of Aβ is a cause or consequence of AD. The interaction between AD and CVD is a topic of considerable current interest. Here, we discuss the role of CVD in Aβ accumulation and the development of AD to provide a new point of view that combination therapies that address the accompanying cerebral microvascular disease may potentiate the efficacy of emerging treatment for AD. PMID:28815226

Comparison of two- and three-dimensional Navier-Stokes solutions with NASA experimental data for CAST-10 airfoil

NASA Technical Reports Server (NTRS)

Swanson, R. Charles; Radespiel, Rolf; Mccormick, V. Edward

1989-01-01

The two-dimensional (2-D) and three-dimensional Navier-Stokes equations are solved for flow over a NAE CAST-10 airfoil model. Recently developed finite-volume codes that apply a multistage time stepping scheme in conjunction with steady state acceleration techniques are used to solve the equations. Two-dimensional results are shown for flow conditions uncorrected and corrected for wind tunnel wall interference effects. Predicted surface pressures from 3-D simulations are compared with those from 2-D calculations. The focus of the 3-D computations is the influence of the sidewall boundary layers. Topological features of the 3-D flow fields are indicated. Lift and drag results are compared with experimental measurements.

Permeabilization of fungal hyphae by the plant defensin NaD1 occurs through a cell wall-dependent process.

PubMed

van der Weerden, Nicole L; Hancock, Robert E W; Anderson, Marilyn A

2010-11-26

The antifungal activity of the plant defensin NaD1 involves specific interaction with the fungal cell wall, followed by permeabilization of the plasma membrane and entry of NaD1 into the cytoplasm. Prior to this study, the role of membrane permeabilization in the activity of NaD1, as well as the relevance of cell wall binding, had not been investigated. To address this, the permeabilization of Fusarium oxysporum f. sp. vasinfectum hyphae by NaD1 was investigated and compared with that by other antimicrobial peptides, including the cecropin-melittin hybrid peptide CP-29, the bovine peptide BMAP-28, and the human peptide LL-37, which are believed to act largely through membrane disruption. NaD1 appeared to permeabilize cells via a novel mechanism that required the presence of the fungal cell wall. NaD1 and Bac2A, a linear variant of the bovine peptide bactenecin, were able to enter the cytoplasm of treated hyphae, indicating that cell death is accelerated by interaction with intracellular targets.

Summary of the Normal-Conducting Accelerating Structures for LEDA and APT

NASA Astrophysics Data System (ADS)

Schneider, J. David

1998-04-01

The accelerator production of tritium (APT) plant requires a continuous (100% duty-factor), 100-mA, 1000--1700-MeV proton beam. Superconducting structures will accelerate protons above about 200 MeV, but room-temperature, normal-conducting (NC) copper structures will be used for lower energies. We will assemble the front 11-MeV portion of this NC accelerator as the low-energy demonstration accelerator (LEDA). This presentation will cover the demonstated operation of the proton injector, the design, fabrication, and tuning status of the 6.7-MeV RFQ, and the design features of the CCDTL (coupled-cavity drift-tube linac) that will accelerate protons to 100 MeV, before use of a conventional CCL (coupled-cavity linac). Several innovative features result in improved performance, ease of use, and improved reliabiltiy. The75-keV injector features a microwave ion source, dual-solenoid transport, and has no electronics at high potential. Its demonstrated high efficiency (less than 800 Watts), excellent proton fraction (>90%), high current (>110 mA), and reliability make it attractive for several other high-current applications. The 6.7-MeV, 350-MHz RFQ is an 8-meter-long, brazed-copper structure with hundreds of cooling channels that carry away the 1.3 MW of waste heat. During beam operation, only the cooling-water temperature is adjustable to maintain structure resonance. LEDA's 700-MHz CCDTL structure is new, combining features of the conventional DTL and CCL structures. All focus magnets are external to the copper accelerating cavities, each of which contains either one or two drift tubes. A `hot model' will validate fabrication, cooling, tuning, and coupling techniques. The LEDA facility is being upgraded with 15 MW of power and cooling utiliites, to support seven 1-MW cw RF systems needed to power all structures. The first few of these 1.3 MW 350-MHz systems are operational, and extensive testing was completed on the critical RF windows. Updates will be given on the development of vacuum, diagnostic, control, and cooling systems, as well as transport lines and beam stops. The unique and very compact, thin-walled beam stop is surrounded by an integral water shield for the prompt neutrons.

How to model the stability of terraced slopes? The case study of Tresenda (northern Italy)

NASA Astrophysics Data System (ADS)

Camera, Corrado; Apuani, Tiziana; Masetti, Marco

2015-04-01

Terraces are very common morphological features all around the Mediterranean Basin. They have been built to adapt the natural morphology of the territory to the development of anthropogenic activities, particularly agriculture. However, the increasing land abandonment during the last century is leading to soil degradation and stability issues, mainly due to lack of maintenance of these peculiar environments. The objective of this study was to develop a coupled hydrologic-stability model to identify possible triggering areas of superficial landslides during intense rainfall events. The model was tested on a slope uphill of the village of Tresenda, in Northern Italy, which experienced several superficial landslides in the last 35 years. Distributed stability analyses are usually carried out using an infinite slope approach, but in the case of terraces some basic assumptions of this method fail: the parallelism between topographical surface and potential sliding surface and the high ratio between slope length and failure surface depth are the most important examples. In addition, the interest is more on the stability of the terrace system (dry stone retaining wall and backfill soil) and not on soil alone. For these reasons, a stability analysis based on the global method of equilibrium is applied and soft coupled to a well know hydrological model (STARWARS). Sections of terrace, one cell wide, are recognized from the base of a wall to the top of the closest downstream one, and each cell (1 x 1 m2) is considered as a slice. The method of Sarma for circular and non-circular failure is applied. The very fine horizontal resolution (1 m) is crucial to take into consideration the hydrogeological and mechanical properties of dry stone walls (0.6-1.0 m wide). A sensitivity analysis was conducted for saturated water content, initial volumetric water content, the cohesion and friction angle of soil and walls and soil depth. The results of the sensitivity analysis showed that instability never occurs if less than 60% of the soil depth is saturated. In addition, a variation of 10% in the cohesion and friction angle of soil leads to changes in critical acceleration (factor of safety) of 4% and 5%, respectively. On the other hand, a variation of 10% in wall cohesion and friction angle leads to changes in the critical acceleration of around 4% and 1.5%, respectively. The use of a soil depth map with slightly different depths caused a different distribution in the number and location of instabilities. This underlines how this parameter, which is difficult to determine at high resolution, plays a central role in controlling location and volume of potential unstable masses. The model was finally evaluated on historical events and it demonstrated to be a good and reliable instrument to reproduce water levels and localise the most critical area for the triggering of superficial landslides on terraced slopes. In detail, field-measured water levels are modelled with a normalized RMSE of about 10%. Regarding stability, the triggering areas of the two superficial landslides occurred in May 1983 were well reproduced both temporally and spatially.

rf breakdown tests of mm-wave metallic accelerating structures

DOE PAGES

Dal Forno, Massimo; Dolgashev, Valery; Bowden, Gordon; ...

2016-01-06

In this study, we explore the physics and frequency-scaling of vacuum rf breakdowns at sub-THz frequencies. We present the experimental results of rf tests performed in metallic mm-wave accelerating structures. These experiments were carried out at the facility for advanced accelerator experimental tests (FACET) at the SLAC National Accelerator Laboratory. The rf fields were excited by the FACET ultrarelativistic electron beam. We compared the performances of metal structures made with copper and stainless steel. The rf frequency of the fundamental accelerating mode, propagating in the structures at the speed of light, varies from 115 to 140 GHz. The traveling wavemore » structures are 0.1 m long and composed of 125 coupled cavities each. We determined the peak electric field and pulse length where the structures were not damaged by rf breakdowns. We calculated the electric and magnetic field correlated with the rf breakdowns using the FACET bunch parameters. The wakefields were calculated by a frequency domain method using periodic eigensolutions. Such a method takes into account wall losses and is applicable to a large variety of geometries. The maximum achieved accelerating gradient is 0.3 GV/m with a peak surface electric field of 1.5 GV/m and a pulse length of about 2.4 ns.« less

3D Resistive MHD Simulations of Formation, Compression, and Acceleration of Compact Tori

NASA Astrophysics Data System (ADS)

Woodruff, Simon; Meyer, Thomas; Stuber, James; Romero-Talamas, Carlos; Brown, Michael; Kaur, Manjit; Schaffner, David

2017-10-01

We present results from extended resistive 3D MHD simulations (NIMROD) pertaining to a new formation method for toroidal plasmas using a reconnection region that forms in a radial implosion, and results from the acceleration of CTs along a drift tube that are accelerated by a coil and are allowed to go tilt unstable and form a helical minimum energy state. The new formation method results from a reconnection region that is generated between two magnetic compression coils that are ramped to 320kV in 2 μs. When the compressing field is aligned anti-parallel to a pre-existing CT, a current sheet and reconnection region forms that accelerates plasma radially inwards up to 500km/s which stagnates and directed energy converts to thermal, raising temperatures to 500eV. When field is aligned parallel to the pre-existing CT, the configuration can be accelerated along a drift tube. For certain ratios of magnetic field to density, the CT goes tilt-unstable forming a twisted flux rope, which can also be accelerated and stagnated on an end wall, where temperature and field increases as the plasma compresses. We compare simulation results with adiabatic scaling relations. Work supported by ARPA-E ALPHA program and DARPA.

Arterial elastic fiber structure. Function and potential roles in acute aortic dissection.

PubMed

Pratt, B; Curci, J

2010-10-01

The lethality of acute aortic dissection is well recognized. Successful treatment and prevention of aortic dissection is going to be dependent upon an improved understanding of the molecular and physiologic events which predispose to dissection development and propagation. In this review, we will focus on the elastic fiber, one of the critical elements of the aortic wall matrix. Mechanical or functional failure of the elastin in the wall of the aorta likely predisposes to dissection as well as the post-dissection aortic degeneration with aneurysm formation. Insight into the role of the elastin and the elastic fiber in aortic dissection has recently been accelerated by research into the molecular mechanisms associated with hereditary propensity for aortic dissection, such as Marfan syndrome. These studies have implicated both structural and metabolic contributions of alterations in the scaffolding proteins in matrix elastic fibers. In particular, increased transforming growth factor-β (TGF-β) activity may play a prominent role in predisposing the aortic wall to dissection. The events which predispose to post-dissection aortic degeneration are somewhat less well defined. However, the loss of the structural integrity of the remaining elastic fibers leaves the wall weaker and prone to dilatation and rupture. It appears likely that the upregulation of several potent proteases, particularly those of the matrix metalloproteinase (MMP) family such as MMP-9, are participating in the subsequent matrix damage. Novel medical treatments based on this pathologic data have been proposed and in some cases have made it to clinical trials. The ongoing study evaluating whether therapeutic inhibition of TGF-β may be useful in reducing the risk of aortic dissection in patients at high risk represents one promising new strategy in the treatment of this deadly disease.

Navier-Stokes solutions of unsteady separation induced by a vortex: Comparison with theory and influence of a moving wall

NASA Astrophysics Data System (ADS)

Obabko, Aleksandr Vladimirovich

Numerical solutions of the unsteady Navier-Stokes equations are considered for the flow induced by a thick-core vortex convecting along an infinite surface in a two-dimensional incompressible flow. The formulation is considered as a model problem of the dynamic-stall vortex and is relevant to other unsteady separation phenomena including vorticity ejections in juncture flows and the vorticity production mechanism in turbulent boundary-layers. Induced by an adverse streamwise pressure gradient due to the presence of the vortex above the wall, a primary recirculation region forms and evolves toward a singular solution of the unsteady non-interacting boundary-layer equations. The resulting eruptive spike provokes a small-scale viscous-inviscid interaction in the high-Reynolds-number regime. In the moderate-Reynolds-numbers regime, the growing recirculation region initiates a large-scale interaction in the form of local changes in the streamwise pressure gradient accelerating the spike formation and resulting small-scale interaction through development of a region of streamwise compression. It also was found to induce regions of streamwise expansion and "child" recirculation regions that contribute to ejections of near-wall vorticity and splitting of the "parent" region into multiple co-rotating eddies. These eddies later merge into a single amalgamated eddy that is observed to pair with the detaching vortex similar to the low-Reynolds-number regime where the large-scale interaction occurs, but there is no spike or subsequent small-scale interaction. It is also found that increasing the wall speed or vortex convection velocity toward a critical value results in solutions that are indicative of flows at lower Reynolds numbers eventually leading to suppression of unsteady separation and vortex detachment processes.

Skin-friction measurements in high-enthalpy hypersonic boundary layers

NASA Astrophysics Data System (ADS)

Goyne, C. P.; Stalker, R. J.; Paull, A.

2003-06-01

Skin-friction measurements are reported for high-enthalpy and high-Mach-number laminar, transitional and turbulent boundary layers. The measurements were performed in a free-piston shock tunnel with air-flow Mach number, stagnation enthalpy and Reynolds numbers in the ranges of 4.4 6.7, 3 13 MJ kg(-1) and 0.16× 10(6) 21× 10(6) , respectively. Wall temperatures were near 300 K and this resulted in ratios of wall enthalpy to flow-stagnation enthalpy in the range of 0.1 0.02. The experiments were performed using rectangular ducts. The measurements were accomplished using a new skin-friction gauge that was developed for impulse facility testing. The gauge was an acceleration compensated piezoelectric transducer and had a lowest natural frequency near 40 kHz. Turbulent skin-friction levels were measured to within a typical uncertainty of ± 7%. The systematic uncertainty in measured skin-friction coefficient was high for the tested laminar conditions; however, to within experimental uncertainty, the skin-friction and heat-transfer measurements were in agreement with the laminar theory of van Driest (1952). For predicting turbulent skin-friction coefficient, it was established that, for the range of Mach numbers and Reynolds numbers of the experiments, with cold walls and boundary layers approaching the turbulent equilibrium state, the Spalding & Chi (1964) method was the most suitable of the theories tested. It was also established that if the heat transfer rate to the wall is to be predicted, then the Spalding & Chi (1964) method should be used in conjunction with a Reynolds analogy factor near unity. If more accurate results are required, then an experimentally observed relationship between the Reynolds analogy factor and the skin-friction coefficient may be applied.

Marked Acceleration of Atherosclerosis following Lactobacillus casei induced Coronary Arteritis in a Mouse Model of Kawasaki Disease

PubMed Central

Chen, Shuang; Lee, Young Ho; Crother, Timothy R.; Fishbein, Michael; Zhang, Wenxuan; Yilmaz, Atilla; Shimada, Kenichi; Schulte, Danica J; Lehman, Thomas J.A.; Shah, Prediman K.; Arditi, Moshe

2012-01-01

Objective To investigate if Lactobacillus casei cell wall extract (LCWE)-induced Kawasaki Disease (KD) accelerates atherosclerosis in hypercholesterolemic mice. Method and Resuslts Apoe−/− or Ldlr−/− mice were injected with LCWE (KD mice) or PBS, fed high fat diet for 8 weeks, and atherosclerotic lesions in aortic sinuses (AS), arch (AC) and whole aorta were assessed. KD mice had larger, more complex aortic lesions with abundant collagen, and both extracellular and intracellular lipid and foam cells, compared to lesions in control mice despite similar cholesterol levels. Both Apoe−/− KD and Ldlr−/− KD mice showed dramatic acceleration in atherosclerosis vs. controls, with increases in en face aortic atherosclerosis and plaque size in both the AS and AC plaques. Accelerated atherosclerosis was associated with increased circulating IL-12p40, IFN-γ, TNF-α, and increased macrophage, DC, and T cell recruitment in lesions. Furthermore, daily injections of the IL-1Ra, which inhibits LCWE induced KD vasculitis, prevented the acceleration of atherosclerosis. Conclusions Our results suggest an important pathophysiologic link between coronary arteritis/vasculitis in the KD mouse model and subsequent atherosclerotic acceleration, supporting the concept that a similar relation may also be present in KD patients. These results also suggest that KD in childhood may predispose to accelerated and early atherosclerosis as adults. PMID:22628430

A Numerical Simulation of Transport Phenomena During the Horizontal Single Belt Casting Process Using an Inclined Feeding System

NASA Astrophysics Data System (ADS)

Xu, Mianguang; Isac, Mihaiela; Guthrie, Roderick I. L.

2018-03-01

Horizontal single belt casting (HSBC) has great potential to replace current conventional continuous casting (CCC) processes for sheet metal production, by directly casting 3 to 1 mm sheet for the automobile industry. In the present paper, two-dimensional mathematical models were developed to study transport phenomena, for the case of an inclined wall feeding system for a liquid aluminum wrought alloy (AA6111). Based on the commercial software ANSYS FLUENT 14.5 and user-defined functions, a two-layer turbulence model was used to examine the fluid flow emanating from a slot nozzle set above a water-cooled, high-speed, steel belt. The Volume of Fluid (VOF) method was used to predict the shape of the melt-air interface. A transformed coordinate system (x', y') was established in order to analyze the fluid flow on the inclined wall of the feeding system. The total pressure gauge gradient (∂p total/∂x) was used to describe the behavior of the melt film inside the slot nozzle of the head box. The modeling results show that during the melt film falling process, the total gauge pressure varies within the slot nozzle, which can decrease the stability of the falling film. The first impingement between the falling film and the inclined refractory wall of the feeding system gives rise to a local oscillation, and this influences the stability of the melt film moving downwards. At the rear meniscus position between the inclined wall and the moving belt, there is a clear vibration of the air-melt interface, together with a recirculation zone. The weak vibration of the air-melt interface could be induced by the periodic variation of the melt-air interface. Moreover, the formation of tiny air pockets is predicted. Finally, on the inclined wall of the feeding system, a suitable length of the transition area is needed to avoid over-acceleration of the melt film due to the force of gravity.

A Numerical Simulation of Transport Phenomena During the Horizontal Single Belt Casting Process Using an Inclined Feeding System

NASA Astrophysics Data System (ADS)

Xu, Mianguang; Isac, Mihaiela; Guthrie, Roderick I. L.

2018-06-01

Horizontal single belt casting (HSBC) has great potential to replace current conventional continuous casting (CCC) processes for sheet metal production, by directly casting 3 to 1 mm sheet for the automobile industry. In the present paper, two-dimensional mathematical models were developed to study transport phenomena, for the case of an inclined wall feeding system for a liquid aluminum wrought alloy (AA6111). Based on the commercial software ANSYS FLUENT 14.5 and user-defined functions, a two-layer turbulence model was used to examine the fluid flow emanating from a slot nozzle set above a water-cooled, high-speed, steel belt. The Volume of Fluid (VOF) method was used to predict the shape of the melt-air interface. A transformed coordinate system ( x', y') was established in order to analyze the fluid flow on the inclined wall of the feeding system. The total pressure gauge gradient ( ∂p total/ ∂x) was used to describe the behavior of the melt film inside the slot nozzle of the head box. The modeling results show that during the melt film falling process, the total gauge pressure varies within the slot nozzle, which can decrease the stability of the falling film. The first impingement between the falling film and the inclined refractory wall of the feeding system gives rise to a local oscillation, and this influences the stability of the melt film moving downwards. At the rear meniscus position between the inclined wall and the moving belt, there is a clear vibration of the air-melt interface, together with a recirculation zone. The weak vibration of the air-melt interface could be induced by the periodic variation of the melt-air interface. Moreover, the formation of tiny air pockets is predicted. Finally, on the inclined wall of the feeding system, a suitable length of the transition area is needed to avoid over-acceleration of the melt film due to the force of gravity.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singer, W.; Singer, X.; Jelezov, I.

Activities of the past several years in developing the technique of forming seamless (weldless) cavity cells by hydroforming are summarized. An overview of the technique developed at DESY for the fabrication of single cells and multicells of the TESLA cavity shape is given and the major rf results are presented. The forming is performed by expanding a seamless tube with internal water pressure while simultaneously swaging it axially. Prior to the expansion the tube is necked at the iris area and at the ends. Tube radii and axial displacements are computer controlled during the forming process in accordance with resultsmore » of finite element method simulations for necking and expansion using the experimentally obtained strain-stress relationship of tube material. In cooperation with industry different methods of niobium seamless tube production have been explored. The most appropriate and successful method is a combination of spinning or deep drawing with flow forming. Several single-cell niobium cavities of the 1.3 GHz TESLA shape were produced by hydroforming. They reached accelerating gradients E acc up to 35 MV/m after buffered chemical polishing (BCP) and up to 42 MV/m after electropolishing (EP). More recent work concentrated on fabrication and testing of multicell and nine-cell cavities. Several seamless two- and three-cell units were explored. Accelerating gradients E acc of 30–35 MV/m were measured after BCP and E acc up to 40 MV/m were reached after EP. Nine-cell niobium cavities combining three three-cell units were completed at the company E. Zanon. These cavities reached accelerating gradients of E acc = 30–35 MV/m. One cavity is successfully integrated in an XFEL cryomodule and is used in the operation of the FLASH linear accelerator at DESY. Additionally the fabrication of bimetallic single-cell and multicell NbCu cavities by hydroforming was successfully developed. Several NbCu clad single-cell and double-cell cavities of the TESLA shape have been fabricated. The clad seamless tubes were produced using hot bonding or explosive bonding and subsequent flow forming. The thicknesses of Nb and Cu layers in the tube wall are about 1 and 3 mm respectively. The rf performance of the best NbCu clad cavities is similar to that of bulk Nb cavities. The highest accelerating gradient achieved was 40 MV/m. The advantages and disadvantages of hydroformed cavities are discussed in this paper.« less

Hydroforming of elliptical cavities

DOE PAGES

Singer, W.; Singer, X.; Jelezov, I.; ...

2015-02-27

Activities of the past several years in developing the technique of forming seamless (weldless) cavity cells by hydroforming are summarized. An overview of the technique developed at DESY for the fabrication of single cells and multicells of the TESLA cavity shape is given and the major rf results are presented. The forming is performed by expanding a seamless tube with internal water pressure while simultaneously swaging it axially. Prior to the expansion the tube is necked at the iris area and at the ends. Tube radii and axial displacements are computer controlled during the forming process in accordance with resultsmore » of finite element method simulations for necking and expansion using the experimentally obtained strain-stress relationship of tube material. In cooperation with industry different methods of niobium seamless tube production have been explored. The most appropriate and successful method is a combination of spinning or deep drawing with flow forming. Several single-cell niobium cavities of the 1.3 GHz TESLA shape were produced by hydroforming. They reached accelerating gradients E acc up to 35 MV/m after buffered chemical polishing (BCP) and up to 42 MV/m after electropolishing (EP). More recent work concentrated on fabrication and testing of multicell and nine-cell cavities. Several seamless two- and three-cell units were explored. Accelerating gradients E acc of 30–35 MV/m were measured after BCP and E acc up to 40 MV/m were reached after EP. Nine-cell niobium cavities combining three three-cell units were completed at the company E. Zanon. These cavities reached accelerating gradients of E acc = 30–35 MV/m. One cavity is successfully integrated in an XFEL cryomodule and is used in the operation of the FLASH linear accelerator at DESY. Additionally the fabrication of bimetallic single-cell and multicell NbCu cavities by hydroforming was successfully developed. Several NbCu clad single-cell and double-cell cavities of the TESLA shape have been fabricated. The clad seamless tubes were produced using hot bonding or explosive bonding and subsequent flow forming. The thicknesses of Nb and Cu layers in the tube wall are about 1 and 3 mm respectively. The rf performance of the best NbCu clad cavities is similar to that of bulk Nb cavities. The highest accelerating gradient achieved was 40 MV/m. The advantages and disadvantages of hydroformed cavities are discussed in this paper.« less

Hydroforming of elliptical cavities

NASA Astrophysics Data System (ADS)

Singer, W.; Singer, X.; Jelezov, I.; Kneisel, P.

2015-02-01

Activities of the past several years in developing the technique of forming seamless (weldless) cavity cells by hydroforming are summarized. An overview of the technique developed at DESY for the fabrication of single cells and multicells of the TESLA cavity shape is given and the major rf results are presented. The forming is performed by expanding a seamless tube with internal water pressure while simultaneously swaging it axially. Prior to the expansion the tube is necked at the iris area and at the ends. Tube radii and axial displacements are computer controlled during the forming process in accordance with results of finite element method simulations for necking and expansion using the experimentally obtained strain-stress relationship of tube material. In cooperation with industry different methods of niobium seamless tube production have been explored. The most appropriate and successful method is a combination of spinning or deep drawing with flow forming. Several single-cell niobium cavities of the 1.3 GHz TESLA shape were produced by hydroforming. They reached accelerating gradients Eacc up to 35 MV /m after buffered chemical polishing (BCP) and up to 42 MV /m after electropolishing (EP). More recent work concentrated on fabrication and testing of multicell and nine-cell cavities. Several seamless two- and three-cell units were explored. Accelerating gradients Eacc of 30 - 35 MV /m were measured after BCP and Eacc up to 40 MV /m were reached after EP. Nine-cell niobium cavities combining three three-cell units were completed at the company E. Zanon. These cavities reached accelerating gradients of Eacc=30 - 35 MV /m . One cavity is successfully integrated in an XFEL cryomodule and is used in the operation of the FLASH linear accelerator at DESY. Additionally the fabrication of bimetallic single-cell and multicell NbCu cavities by hydroforming was successfully developed. Several NbCu clad single-cell and double-cell cavities of the TESLA shape have been fabricated. The clad seamless tubes were produced using hot bonding or explosive bonding and subsequent flow forming. The thicknesses of Nb and Cu layers in the tube wall are about 1 and 3 mm respectively. The rf performance of the best NbCu clad cavities is similar to that of bulk Nb cavities. The highest accelerating gradient achieved was 40 MV /m . The advantages and disadvantages of hydroformed cavities are discussed in this paper.

Pulsatile flows and wall-shear stresses in models simulating normal and stenosed aortic arches

NASA Astrophysics Data System (ADS)

Huang, Rong Fung; Yang, Ten-Fang; Lan, Y.-K.

2010-03-01

Pulsatile aqueous glycerol solution flows in the models simulating normal and stenosed human aortic arches are measured by means of particle image velocimetry. Three transparent models were used: normal, 25% stenosed, and 50% stenosed aortic arches. The Womersley parameter, Dean number, and time-averaged Reynolds number are 17.31, 725, and 1,081, respectively. The Reynolds numbers based on the peak velocities of the normal, 25% stenosed, and 50% stenosed aortic arches are 2,484, 3,456, and 3,931, respectively. The study presents the temporal/spatial evolution processes of the flow pattern, velocity distribution, and wall-shear stress during the systolic and diastolic phases. It is found that the flow pattern evolving in the central plane of normal and stenosed aortic arches exhibits (1) a separation bubble around the inner arch, (2) a recirculation vortex around the outer arch wall upstream of the junction of the brachiocephalic artery, (3) an accelerated main stream around the outer arch wall near the junctions of the left carotid and the left subclavian arteries, and (4) the vortices around the entrances of the three main branches. The study identifies and discusses the reasons for the flow physics’ contribution to the formation of these features. The oscillating wall-shear stress distributions are closely related to the featured flow structures. On the outer wall of normal and slightly stenosed aortas, large wall-shear stresses appear in the regions upstream of the junction of the brachiocephalic artery as well as the corner near the junctions of the left carotid artery and the left subclavian artery. On the inner wall, the largest wall-shear stress appears in the region where the boundary layer separates.

Electron beam ion sources for use in second generation synchrotrons for medical particle therapy

NASA Astrophysics Data System (ADS)

Zschornack, G.; Ritter, E.; Schmidt, M.; Schwan, A.

2014-02-01

Cyclotrons and first generation synchrotrons are the commonly applied accelerators in medical particle therapy nowadays. Next generation accelerators such as Rapid Cycling Medical Synchrotrons (RCMS), direct drive accelerators, or dielectric wall accelerators have the potential to improve the existing accelerator techniques in this field. Innovative accelerator concepts for medical particle therapy can benefit from ion sources which meet their special requirements. In the present paper we report on measurements with a superconducting Electron Beam Ion Source, the Dresden EBIS-SC, under the aspect of application in combination with RCMS as a well proven technology. The measurements indicate that this ion source can offer significant advantages for medical particle therapy. We show that a superconducting EBIS can deliver ion pulses of medically relevant ions such as protons, C4 + and C6 + ions with intensities and frequencies required for RCMS [S. Peggs and T. Satogata, "A survey of Hadron therapy accelerator technology," in Proceedings of PAC07, BNL-79826- 2008-CP, Albuquerque, New Mexico, USA, 2007; A. Garonna, U. Amaldi et al., "Cyclinac medical accelerators using pulsed C6 +/H+_2 ion sources," in Proceedings of EBIST 2010, Stockholm, Sweden, July 2010]. Ion extraction spectra as well as individual ion pulses have been measured. For example, we report on the generation of proton pulses with up to 3 × 109 protons per pulse and with frequencies of up to 1000 Hz at electron beam currents of 600 mA.

Dielectric supported radio-frequency cavities

DOEpatents

Yu, David U. L.; Lee, Terry G.

2000-01-01

A device which improves the electrical and thermomechanical performance of an RF cavity, for example, in a disk-loaded accelerating structure. A washer made of polycrystalline diamond is brazed in the middle to a copper disk washer and at the outer edge to the plane wave transformer tank wall, thus dissipating heat from the copper disk to the outer tank wall while at the same time providing strong mechanical support to the metal disk. The washer structure eliminates the longitudinal connecting rods and cooling channels used in the currently available cavities, and as a result minimizes problems such as shunt impedance degradation and field distortion in the plane wave transformer, and mechanical deflection and uneven cooling of the disk assembly.

Review of Electronics Based on Single-Walled Carbon Nanotubes.

PubMed

Cao, Yu; Cong, Sen; Cao, Xuan; Wu, Fanqi; Liu, Qingzhou; Amer, Moh R; Zhou, Chongwu

2017-08-14

Single-walled carbon nanotubes (SWNTs) are extremely promising materials for building next-generation electronics due to their unique physical and electronic properties. In this article, we will review the research efforts and achievements of SWNTs in three electronic fields, namely analog radio-frequency electronics, digital electronics, and macroelectronics. In each SWNT-based electronic field, we will present the major challenges, the evolutions of the methods to overcome these challenges, and the state-of-the-art of the achievements. At last, we will discuss future directions which could lead to the broad applications of SWNTs. We hope this review could inspire more research on SWNT-based electronics, and accelerate the applications of SWNTs.

Wall-loss distribution of charge breeding ions in an electron cyclotron resonance ion source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jeong, S. C.; Oyaizu, M.; Imai, N.

2012-02-15

We investigated the ion-loss distribution on the sidewall of an electron cyclotron resonance (ECR) plasma chamber using the 18-GHz ECR charge breeder at the Tokai Radioactive Ion Accelerator Complex (TRIAC). Similarities and differences between the ion-loss distributions (longitudinal and azimuthal) of different ion species (i.e., radioactive {sup 111}In{sup 1+} and {sup 140}Xe{sup 1+} ions that are typical volatile and nonvolatile elements) was qualitatively discussed to understand the element dependence of the charge breeding efficiency. Especially, the similarities represent universal ion loss characteristics in an ECR charge breeder, which are different from the loss patterns of electrons on the ECRIS wall.

Evidence for Ancient Mesoamerican Earthquakes

NASA Astrophysics Data System (ADS)

Kovach, R. L.; Garcia, B.

2001-12-01

Evidence for past earthquake damage at Mesoamerican ruins is often overlooked because of the invasive effects of tropical vegetation and is usually not considered as a casual factor when restoration and reconstruction of many archaeological sites are undertaken. Yet the proximity of many ruins to zones of seismic activity would argue otherwise. Clues as to the types of damage which should be soughtwere offered in September 1999 when the M = 7.5 Oaxaca earthquake struck the ruins of Monte Alban, Mexico, where archaeological renovations were underway. More than 20 structures were damaged, 5 of them seriously. Damage features noted were walls out of plumb, fractures in walls, floors, basal platforms and tableros, toppling of columns, and deformation, settling and tumbling of walls. A Modified Mercalli Intensity of VII (ground accelerations 18-34 %b) occurred at the site. Within the diffuse landward extension of the Caribbean plate boundary zone M = 7+ earthquakes occur with repeat times of hundreds of years arguing that many Maya sites were subjected to earthquakes. Damage to re-erected and reinforced stelae, walls, and buildings were witnessed at Quirigua, Guatemala, during an expedition underway when then 1976 M = 7.5 Guatemala earthquake on the Motagua fault struck. Excavations also revealed evidence (domestic pttery vessels and skeleton of a child crushed under fallen walls) of an ancient earthquake occurring about the teim of the demise and abandonment of Quirigua in the late 9th century. Striking evidence for sudden earthquake building collapse at the end of the Mayan Classic Period ~A.D. 889 was found at Benque Viejo (Xunantunich), Belize, located 210 north of Quirigua. It is argued that a M = 7.5 to 7.9 earthquake at the end of the Maya Classic period centered in the vicinity of the Chixoy-Polochic and Motagua fault zones cound have produced the contemporaneous earthquake damage to the above sites. As a consequences this earthquake may have accelerated the collapse of the hiearchical authority at these locations and may have contributed to the end of the Classic culture at other nearby sites in proximity to the Caribbean plate boundary zone.

Efficient proton acceleration and focusing by an ultraintense laser interacting with a parabolic double concave target with an extended rear

NASA Astrophysics Data System (ADS)

Bake, Muhammad Ali; Xie, Bai-Song; Aimidula, Aimierding; Wang, Hong-Yu

2013-07-01

A new scheme for acceleration and focusing of protons via an improved parabolic double concave target irradiated by an ultraintense laser pulse is proposed. When an intense laser pulse illuminates a concave target, the hot electrons are concentrated on the focal region of the rear cavity and they form a strong space-charge-separation field, which accelerates the protons. For a simple concave target, the proton energy spectrum becomes very broad outside the rear cavity because of transverse divergence of the electromagnetic fields. However, particle-in-cell simulations show that, when the concave target has an extended rear, the hot electrons along the wall surface induce a transverse focusing sheath field, resulting in a clear enhancement of proton focusing, which makes the lower proton energy spread, while, leads to a little reduction of the proton bunch peak energy.

Crash tests of three identical low-wing single-engine airplane

NASA Technical Reports Server (NTRS)

Castle, C. B.; Alfaro-Bou, E.

1983-01-01

Three identical four place, low wing single engine airplane specimens with nominal masses of 1043 kg were crash tested under controlled free flight conditions. The tests were conducted at the same nominal velocity of 25 m/sec along the flight path. Two airplanes were crashed on a concrete surface (at 10 and 30 deg pitch angles), and one was crashed on soil (at a -30 deg pitch angle). The three tests revealed that the specimen in the -30 deg test on soil sustained massive structural damage in the engine compartment and fire wall. Also, the highest longitudinal cabin floor accelerations occurred in this test. Severe damage, but of lesser magnitude, occurred in the -30 deg test on concrete. The highest normal cabin floor accelerations occurred in this test. The least structural damage and lowest accelerations occurred in the 10 deg test on concrete.

Electron-Beam Dynamics for an Advanced Flash-Radiography Accelerator

DOE PAGES

Ekdahl, Carl

2015-11-17

Beam dynamics issues were assessed for a new linear induction electron accelerator being designed for multipulse flash radiography of large explosively driven hydrodynamic experiments. Special attention was paid to equilibrium beam transport, possible emittance growth, and beam stability. Especially problematic would be high-frequency beam instabilities that could blur individual radiographic source spots, low-frequency beam motion that could cause pulse-to-pulse spot displacement, and emittance growth that could enlarge the source spots. Furthermore, beam physics issues were examined through theoretical analysis and computer simulations, including particle-in-cell codes. Beam instabilities investigated included beam breakup, image displacement, diocotron, parametric envelope, ion hose, and themore » resistive wall instability. The beam corkscrew motion and emittance growth from beam mismatch were also studied. It was concluded that a beam with radiographic quality equivalent to the present accelerators at Los Alamos National Laboratory will result if the same engineering standards and construction details are upheld.« less

Electron-beam dynamics for an advanced flash-radiography accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ekdahl, Carl August Jr.

2015-06-22

Beam dynamics issues were assessed for a new linear induction electron accelerator. Special attention was paid to equilibrium beam transport, possible emittance growth, and beam stability. Especially problematic would be high-frequency beam instabilities that could blur individual radiographic source spots, low-frequency beam motion that could cause pulse-to-pulse spot displacement, and emittance growth that could enlarge the source spots. Beam physics issues were examined through theoretical analysis and computer simulations, including particle-in cell (PIC) codes. Beam instabilities investigated included beam breakup (BBU), image displacement, diocotron, parametric envelope, ion hose, and the resistive wall instability. Beam corkscrew motion and emittance growth frommore » beam mismatch were also studied. It was concluded that a beam with radiographic quality equivalent to the present accelerators at Los Alamos will result if the same engineering standards and construction details are upheld.« less

Gravitational stresses in long symmetric ridges and valleys in anisotropic rock

USGS Publications Warehouse

Pan, E.; Amadei, B.; Savage, W.Z.

1994-01-01

The effect of topography and rock mass anisotropy on gravitational stresses in long isolated symmetric ridges and valleys is modeled using an analytical method proposed earlier by the first two authors. The rock mass deforms under a condition of plane strain. A parametric study is presented on the effect of (1) topography, (2) orientation of anisotropy and (3) degree of anisotropy on the magnitude and distribution of gravitational stresses in transversely isotropic rock masses with planes of anisotropy striking parallel to the ridge or valley axis. It is found that compressive stresses develop near ridge crests and that tensile stresses develop in valley bottoms and valley walls. The magnitude of the gravitational stresses is of the order of the characteristics stress ??{variant}g??b?? where ??{variant} is the rock density, g is the gravitational acceleration and ??b?? is the height of the ridge or depth of the valley. ?? 1994.

Antibiotic development challenges: the various mechanisms of action of antimicrobial peptides and of bacterial resistance

PubMed Central

Guilhelmelli, Fernanda; Vilela, Nathália; Albuquerque, Patrícia; Derengowski, Lorena da S.; Silva-Pereira, Ildinete; Kyaw, Cynthia M.

2013-01-01

Antimicrobial peptides (AMPs) are natural antibiotics produced by various organisms such as mammals, arthropods, plants, and bacteria. In addition to antimicrobial activity, AMPs can induce chemokine production, accelerate angiogenesis, and wound healing and modulate apoptosis in multicellular organisms. Originally, their antimicrobial mechanism of action was thought to consist solely of an increase in pathogen cell membrane permeability, but it has already been shown that several AMPs do not modulate membrane permeability in the minimal lethal concentration. Instead, they exert their effects by inhibiting processes such as protein and cell wall synthesis, as well as enzyme activity, among others. Although resistance to these molecules is uncommon several pathogens developed different strategies to overcome AMPs killing such as surface modification, expression of efflux pumps, and secretion of proteases among others. This review describes the various mechanisms of action of AMPs and how pathogens evolve resistance to them. PMID:24367355

Exploring the molecular mechanisms of parasite-host interactions with a view towards new therapeutics and vaccines.

PubMed

Cross, Megan; Klepzig, Emma; Dallaston, Madeleine; Young, Neil D; Bailey, Ulla-Maja; Mason, Lyndel; Jones, Malcolm K; Gasser, Robin B; Hofmann, Andreas

Despite the massive disease burden worldwide caused by parasitic nematodes and other infectious pathogens, the molecular basis of many infectious diseases caused by these pathogens has been unduly neglected for a long time. Therefore, accelerated progress towards novel therapeutics, and ultimately control of such infectious diseases, is of crucial importance. Capitalising on the wealth of data becoming available from proteomic and genomic studies, new protein targets at the pathogen-host interface can be identified and subjected to protein-based explorations of the molecular basis of pathogen-host interactions. By combining the use of systems and structural biology methodologies, insights into the structural and molecular mechanisms of these interactions can assist in the development of therapeutics and/or vaccines. This brief review examines two different proteins from the body wall of blood flukes - annexins and the stress-induced phosphoprotein 1 - both of which are presently interesting targets for the development of therapeutics.

Redistribution Principle Approach for Evaluation of Seismic Active Earth Pressure Behind Retaining Wall

NASA Astrophysics Data System (ADS)

Maskar, A. D.; Madhekar, S. N.; Phatak, D. R.

2017-11-01

The knowledge of seismic active earth pressure behind the rigid retaining wall is very essential in the design of retaining wall in earthquake prone regions. Commonly used Mononobe-Okabe (MO) method considers pseudo-static approach. Recently there are many pseudo-dynamic methods used to evaluate the seismic earth pressure. However, available pseudo-static and pseudo-dynamic methods do not incorporate the effect of wall movement on the earth pressure distribution. Dubrova (Interaction between soils and structures, Rechnoi Transport, Moscow, 1963) was the first, who considered such effect and till date, it is used for cohesionless soil, without considering the effect of seismicity. In this paper, Dubrova's model based on redistribution principle, considering the seismic effect has been developed. It is further used to compute the distribution of seismic active earth pressure, in a more realistic manner, by considering the effect of wall movement on the earth pressure, as it is displacement based method. The effects of a wide range of parameters like soil friction angle (ϕ), wall friction angle (δ), horizontal and vertical seismic acceleration coefficients (kh and kv); on seismic active earth pressure (Kae) have been studied. Results are presented for comparison of pseudo-static and pseudo-dynamic methods, to highlight the realistic, non-linearity of seismic active earth pressure distribution. The current study results in the variation of Kae with kh in the same manner as that of MO method and Choudhury and Nimbalkar (Geotech Geol Eng 24(5):1103-1113, 2006) study. To increase in ϕ, there is a reduction in static as well as seismic earth pressure. Also, by keeping constant ϕ value, as kh increases from 0 to 0.3, earth pressure increases; whereas as δ increases, active earth pressure decreases. The seismic active earth pressure coefficient (Kae) obtained from the present study is approximately same as that obtained by previous researchers. Though seismic earth pressure obtained by pseudo-dynamic approach and seismic earth pressure obtained by redistribution principle have different background of formulation, the final earth pressure distribution is approximately same.

Electron Transport and Ion Acceleration in a Low-power Cylindrical Hall Thruster

DOE Office of Scientific and Technical Information (OSTI.GOV)

A. Smirnov; Y. Raitses; N.J. Fisch

2004-06-24

Conventional annular Hall thrusters become inefficient when scaled to low power. Cylindrical Hall thrusters, which have lower surface-to-volume ratio, are therefore more promising for scaling down. They presently exhibit performance comparable with conventional annular Hall thrusters. Electron cross-field transport in a 2.6 cm miniaturized cylindrical Hall thruster (100 W power level) has been studied through the analysis of experimental data and Monte Carlo simulations of electron dynamics in the thruster channel. The numerical model takes into account elastic and inelastic electron collisions with atoms, electron-wall collisions, including secondary electron emission, and Bohm diffusion. We show that in order to explainmore » the observed discharge current, the electron anomalous collision frequency {nu}{sub B} has to be on the order of the Bohm value, {nu}{sub B} {approx} {omega}{sub c}/16. The contribution of electron-wall collisions to cross-field transport is found to be insignificant. The plasma density peak observed at the axis of the 2.6 cm cylindrical Hall thruster is likely to be due to the convergent flux of ions, which are born in the annular part of the channel and accelerated towards the thruster axis.« less

Advanced space propulsion thruster research

NASA Technical Reports Server (NTRS)

Wilbur, P. J.

1981-01-01

Experiments showed that stray magnetic fields can adversely affect the capacity of a hollow cathode neutralizer to couple to an ion beam. Magnetic field strength at the neutralizer cathode orifice is a crucial factor influencing the coupling voltage. The effects of electrostatic accelerator grid aperture diameters on the ion current extraction capabilities were examined experimentally to describe the divergence, deflection, and current extraction capabilities of grids with the screen and accelerator apertures displaced relative to one another. Experiments performed in orificed, mercury hollow cathodes support the model of field enhanced thermionic electron mission from cathode inserts. Tests supported the validity of a thermal model of the cathode insert. A theoretical justification of a Saha equation model relating cathode plasma properties is presented. Experiments suggest that ion loss rates to discharge chamber walls can be controlled. A series of new discharge chamber magnetic field configurations were generated in the flexible magnetic field thruster and their effect on performance was examined. A technique used in the thruster to measure ion currents to discharge chamber walls is described. Using these ion currents the fraction of ions produced that are extracted from the discharge chamber and the energy cost of plasma ions are computed.

Toward the optimization of control of unsteady separation

NASA Technical Reports Server (NTRS)

Shen, S. F.; Xiao, Zheng-Hua

1992-01-01

Regardless of our understanding of the complicated physical process, means can always be found to alter the occurrence and development of unsteady separation. To be able to optimize the control of separation, however, requires the identification of the critical aspects to which the intervention may be focused and achieve the desired result with minimum waste of effort. The Lagrangian analysis of unsteady boundary-layer traces the trajectories of individual fluid particles and reveals the 'bad seeds' that, through extreme deformation in the direction normal to the wall, eventually develop into a virtual barrier and cause the ejection of boundary-layer material into the main stream. It follows logically that separation can be triggered or delayed most effectively by targeting these 'bad seeds.' Since they are normally interior points of the boundary layer, attempts to influence them through the boundary conditions are necessarily indirect. Furthermore, as the strategy has to be the modification of the growing process of the 'bad seeds,' whatever may be the intervention scheme, it needs to be strong enough and early enough. In Shen and Wu, examples of how acceleration/deceleration of the two dimensional body, as well as the moving wall of a rotating cylinder, may affect the development of the bad seed toward separation are shown. In fact it was mentioned therein that the results might be the first step for a feasibility study of the control of unsteady separation. Presented are additional results of applying suction to an impulsively started circular cylinder.

High-throughput, Highly Sensitive Analyses of Bacterial Morphogenesis Using Ultra Performance Liquid Chromatography*

PubMed Central

Desmarais, Samantha M.; Tropini, Carolina; Miguel, Amanda; Cava, Felipe; Monds, Russell D.; de Pedro, Miguel A.; Huang, Kerwyn Casey

2015-01-01

The bacterial cell wall is a network of glycan strands cross-linked by short peptides (peptidoglycan); it is responsible for the mechanical integrity of the cell and shape determination. Liquid chromatography can be used to measure the abundance of the muropeptide subunits composing the cell wall. Characteristics such as the degree of cross-linking and average glycan strand length are known to vary across species. However, a systematic comparison among strains of a given species has yet to be undertaken, making it difficult to assess the origins of variability in peptidoglycan composition. We present a protocol for muropeptide analysis using ultra performance liquid chromatography (UPLC) and demonstrate that UPLC achieves resolution comparable with that of HPLC while requiring orders of magnitude less injection volume and a fraction of the elution time. We also developed a software platform to automate the identification and quantification of chromatographic peaks, which we demonstrate has improved accuracy relative to other software. This combined experimental and computational methodology revealed that peptidoglycan composition was approximately maintained across strains from three Gram-negative species despite taxonomical and morphological differences. Peptidoglycan composition and density were maintained after we systematically altered cell size in Escherichia coli using the antibiotic A22, indicating that cell shape is largely decoupled from the biochemistry of peptidoglycan synthesis. High-throughput, sensitive UPLC combined with our automated software for chromatographic analysis will accelerate the discovery of peptidoglycan composition and the molecular mechanisms of cell wall structure determination. PMID:26468288

Experimental investigation of compliant wall surface deformation in a turbulent channel flow

NASA Astrophysics Data System (ADS)

Zhang, Cao; Wang, Jin; Katz, Joseph

2016-11-01

The dynamic response of a compliant wall under a turbulent channel flow is investigated by simultaneously measuring the time-resolved, 3D flow field (using tomographic PIV) and the 2D surface deformation (using interferometry). The pressure distributions are calculated by spatially integrating the material acceleration field. The Reynolds number is Reτ = 2300, and the centerline velocity (U0) is 15% of the material shear speed. The wavenumber-frequency spectra of the wall deformation contain a non-advected low-frequency component and advected modes, some traveling downstream at U0 and others at 0.72U0. Trends in the wall dynamics are elucidated by correlating the deformation with flow variables. The spatial pressure-deformation correlations peak at y/ h 0.12 (h is half channel height), the elevation of Reynolds shear stress maximum in the log-layer. Streamwise lagging of the deformation behind the pressure is caused in part by phase-lag of the pressure with decreasing distance from the wall, and in part by material damping. Positive deformations (bumps) are preferentially associated with ejections, which involve spanwise vortices located downstream and quasi-streamwise vortices with spanwise offset, consistent with hairpin-like structures. The negative deformations (dents) are preferentially associated with pressure maxima at the transition between an upstream sweep to a downstream ejection. Sponsored by ONR.

Experimental Investigation of Compliant Wall Surface Deformation in Turbulent Boundary Layer

NASA Astrophysics Data System (ADS)

Wang, Jin; Agarwal, Karuna; Katz, Joseph

2017-11-01

On-going research integrates Tomographic PIV (TPIV) with Mach-Zehnder Interferometry (MZI) to measure the correlations between deformation of a compliant wall and a turbulent channel flow or a boundary layer. Aiming to extend the scope to two-way coupling, in the present experiment the wall properties have been designed, based on a theoretical analysis, to increase the amplitude of deformation to several μm, achieving the same order of magnitude as the boundary layer wall unit (5-10 μm). It requires higher speeds and a softer surface that has a Young's modulus of 0.1MPa (vs. 1Mpa before), as well as proper thickness (5 mm) that maximize the wall response to excitation at scales that fall within the temporal and spatial resolution of the instruments. The experiments are performed in a water tunnel extension to the JHU refractive index matched facility. The transparent compliant surface is made of PDMS molded on the tunnel window, and measurements are performed at friction velocity Reynolds numbers in the 1000-7000 range. MZI measures the 2D surface deformation as several magnifications. The time-resolved 3D pressure distribution is determined by calculating to spatial distribution of material acceleration from the TPIV data and integrating it using a GPU-based, parallel-line, omni-directional integration method. ONR.

K-t GRAPPA-accelerated 4D flow MRI of liver hemodynamics: influence of different acceleration factors on qualitative and quantitative assessment of blood flow.

PubMed

Stankovic, Zoran; Fink, Jury; Collins, Jeremy D; Semaan, Edouard; Russe, Maximilian F; Carr, James C; Markl, Michael; Langer, Mathias; Jung, Bernd

2015-04-01

We sought to evaluate the feasibility of k-t parallel imaging for accelerated 4D flow MRI in the hepatic vascular system by investigating the impact of different acceleration factors. k-t GRAPPA accelerated 4D flow MRI of the liver vasculature was evaluated in 16 healthy volunteers at 3T with acceleration factors R = 3, R = 5, and R = 8 (2.0 × 2.5 × 2.4 mm(3), TR = 82 ms), and R = 5 (TR = 41 ms); GRAPPA R = 2 was used as the reference standard. Qualitative flow analysis included grading of 3D streamlines and time-resolved particle traces. Quantitative evaluation assessed velocities, net flow, and wall shear stress (WSS). Significant scan time savings were realized for all acceleration factors compared to standard GRAPPA R = 2 (21-71 %) (p < 0.001). Quantification of velocities and net flow offered similar results between k-t GRAPPA R = 3 and R = 5 compared to standard GRAPPA R = 2. Significantly increased leakage artifacts and noise were seen between standard GRAPPA R = 2 and k-t GRAPPA R = 8 (p < 0.001) with significant underestimation of peak velocities and WSS of up to 31 % in the hepatic arterial system (p <0.05). WSS was significantly underestimated up to 13 % in all vessels of the portal venous system for k-t GRAPPA R = 5, while significantly higher values were observed for the same acceleration with higher temporal resolution in two veins (p < 0.05). k-t acceleration of 4D flow MRI is feasible for liver hemodynamic assessment with acceleration factors R = 3 and R = 5 resulting in a scan time reduction of at least 40 % with similar quantitation of liver hemodynamics compared with GRAPPA R = 2.

Burn Propagation in a PBX 9501 Thermal Explosion

NASA Astrophysics Data System (ADS)

Henson, B. F.; Smilowitz, L.; Romero, J. J.; Sandstrom, M. M.; Asay, B. W.; Schwartz, C.; Saunders, A.; Merrill, F.; Morris, C.; Murray, M. M.; McNeil, W. V.; Marr-Lyon, M.; Rightley, P. M.

2007-12-01

We have applied proton radiography to study the conversion of solid density to gaseous combustion products subsequent to ignition of a thermal explosion in PBX 9501. We apply a thermal boundary condition to the cylindrical walls of the case, ending with an induction period at 205 C. We then introduce a laser pulse that accelerates the thermal ignition and synchronizes the explosion with the proton accelerator. We then obtain fast, synchronized images of the evolution of density loss with few microsecond resolution during the approximately 100 microsecond duration of the explosion. We present images of the solid explosive during the explosion and discuss measured rates and assumed mechanisms of burning the role of pressure in this internal burning.

Experimental demonstration of the stabilizing effect of dielectric coatings on magnetically accelerated imploding metallic liners

DOE Office of Scientific and Technical Information (OSTI.GOV)

Awe, Thomas James; Peterson, Kyle J.; Yu, Edmund P.

Enhanced implosion stability has been experimentally demonstrated for magnetically accelerated liners that are coated with 70 μm of dielectric. The dielectric tamps liner-mass redistribution from electrothermal instabilities and also buffers coupling of the drive magnetic field to the magneto-Rayleigh-Taylor instability. A dielectric-coated and axially premagnetized beryllium liner was radiographed at a convergence ratio [CR=R in,0/R in(z,t)] of 20, which is the highest CR ever directly observed for a strengthless magnetically driven liner. Lastly, the inner-wall radius R in(z,t) displayed unprecedented uniformity, varying from 95 to 130 μm over the 4.0 mm axial height captured by the radiograph.

Combined Mini-Cylex & Disk Acceleration Tests in Type K Copper

DOE PAGES

Maines, Warren Russell; Kittell, David E.; Hobbs, Michael L.

2018-04-16

In this work, we combined the miniature cylinder expansion test (Mini-Cylex), with the Disk Acceleration Test (DAX) using Type K copper, Picatinny Liquid Explosive, and photonic Doppler velocimetry. We estimated the CJ state using plate reverberation methods at the test cap. We extracted velocities at 2, 7, and 10 volume expansions to fit Jones-Wilkins-Lee Equation of State and estimated Gurney velocity at the tube wall. The test also provides an additional method to estimate reaction products Hugoniot through knowledge of the copper test cap. Our experiments and simulations are within expected uncertainty. Lastly, the test and the analysis effectively reducemore » costs while keeping or increasing fidelity.« less

Simulation of the Focal Spot of the Accelerator Bremsstrahlung Radiation

NASA Astrophysics Data System (ADS)

Sorokin, V.; Bespalov, V.

2016-06-01

Testing of thick-walled objects by bremsstrahlung radiation (BR) is primarily performed via high-energy quanta. The testing parameters are specified by the focal spot size of the high-energy bremsstrahlung radiation. In determining the focal spot size, the high- energy BR portion cannot be experimentally separated from the low-energy BR to use high- energy quanta only. The patterns of BR focal spot formation have been investigated via statistical modeling of the radiation transfer in the target material. The distributions of BR quanta emitted by the target for different energies and emission angles under normal distribution of the accelerated electrons bombarding the target have been obtained, and the ratio of the distribution parameters has been determined.

Experimental demonstration of the stabilizing effect of dielectric coatings on magnetically accelerated imploding metallic liners

DOE PAGES

Awe, Thomas James; Peterson, Kyle J.; Yu, Edmund P.; ...

2016-02-10

Enhanced implosion stability has been experimentally demonstrated for magnetically accelerated liners that are coated with 70 μm of dielectric. The dielectric tamps liner-mass redistribution from electrothermal instabilities and also buffers coupling of the drive magnetic field to the magneto-Rayleigh-Taylor instability. A dielectric-coated and axially premagnetized beryllium liner was radiographed at a convergence ratio [CR=R in,0/R in(z,t)] of 20, which is the highest CR ever directly observed for a strengthless magnetically driven liner. Lastly, the inner-wall radius R in(z,t) displayed unprecedented uniformity, varying from 95 to 130 μm over the 4.0 mm axial height captured by the radiograph.

Combined Mini-Cylex & Disk Acceleration Tests in Type K Copper

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maines, Warren Russell; Kittell, David E.; Hobbs, Michael L.

In this work, we combined the miniature cylinder expansion test (Mini-Cylex), with the Disk Acceleration Test (DAX) using Type K copper, Picatinny Liquid Explosive, and photonic Doppler velocimetry. We estimated the CJ state using plate reverberation methods at the test cap. We extracted velocities at 2, 7, and 10 volume expansions to fit Jones-Wilkins-Lee Equation of State and estimated Gurney velocity at the tube wall. The test also provides an additional method to estimate reaction products Hugoniot through knowledge of the copper test cap. Our experiments and simulations are within expected uncertainty. Lastly, the test and the analysis effectively reducemore » costs while keeping or increasing fidelity.« less

Extended DBI massive gravity with generalized fiducial metric

NASA Astrophysics Data System (ADS)

Chullaphan, Tossaporn; Tannukij, Lunchakorn; Wongjun, Pitayuth

2015-06-01

We consider an extended model of DBI massive gravity by generalizing the fiducial metric to be an induced metric on the brane corresponding to a domain wall moving in five-dimensional Schwarzschild-Anti-de Sitter spacetime. The model admits all solutions of FLRW metric including flat, closed and open geometries while the original one does not. The background solutions can be divided into two branches namely self-accelerating branch and normal branch. For the self-accelerating branch, the graviton mass plays the role of cosmological constant to drive the late-time acceleration of the universe. It is found that the number degrees of freedom of gravitational sector is not correct similar to the original DBI massive gravity. There are only two propagating degrees of freedom from tensor modes. For normal branch, we restrict our attention to a particular class of the solutions which provides an accelerated expansion of the universe. It is found that the number of degrees of freedom in the model is correct. However, at least one of them is ghost degree of freedom which always present at small scale implying that the theory is not stable.

Bacteroidaceae in Thromboembolic Disease: Effects of Cell Wall Components on Blood Coagulation In Vivo and In Vitro

PubMed Central

Bjornson, H. S.; Hill, E. O.

1973-01-01

The effects of Bacteroides sp., Fusobacterium mortiferum, Bacteroides fragilis, and Sphaerophorus necrophorus on various parameters of blood coagulation in vivo and in vitro were determined and compared to the coagulation effects of Escherichia coli and Salmonella minnesota, wild type and R595. Intravenous injection of washed cells, culture filtrate, lipopolysaccharide, or lipid A of the anaerobic gram-negative microorganisms into mice resulted in acceleration of coagulation. Lipopolysaccharide and lipid A of the anaerobic microorganisms had no apparent effect on circulating platelets in mice or rabbits and did not cause aggregation of human platelets in vitro. Washed cells, lipopolysaccharide, and lipid A of Bacteroides sp. and F. mortiferum also significantly accelerated the clotting time of recalcified platelet poor normal human plasma and C6-deficient rabbit plasma. Lipid A, but not lipopolysaccharide, of E. coli and washed cells of S. minnesota R595 accelerated coagulation by a similar mechanism. These results indicated that Bacteroides sp. and F. mortiferum can accelerate blood coagulation in vivo and in vitro by a mechanism which does not involve platelets or terminal components of complement. PMID:4594118

Numerical Nuclear Second Derivatives on a Computing Grid: Enabling and Accelerating Frequency Calculations on Complex Molecular Systems.

PubMed

Yang, Tzuhsiung; Berry, John F

2018-06-04

The computation of nuclear second derivatives of energy, or the nuclear Hessian, is an essential routine in quantum chemical investigations of ground and transition states, thermodynamic calculations, and molecular vibrations. Analytic nuclear Hessian computations require the resolution of costly coupled-perturbed self-consistent field (CP-SCF) equations, while numerical differentiation of analytic first derivatives has an unfavorable 6 N ( N = number of atoms) prefactor. Herein, we present a new method in which grid computing is used to accelerate and/or enable the evaluation of the nuclear Hessian via numerical differentiation: NUMFREQ@Grid. Nuclear Hessians were successfully evaluated by NUMFREQ@Grid at the DFT level as well as using RIJCOSX-ZORA-MP2 or RIJCOSX-ZORA-B2PLYP for a set of linear polyacenes with systematically increasing size. For the larger members of this group, NUMFREQ@Grid was found to outperform the wall clock time of analytic Hessian evaluation; at the MP2 or B2LYP levels, these Hessians cannot even be evaluated analytically. We also evaluated a 156-atom catalytically relevant open-shell transition metal complex and found that NUMFREQ@Grid is faster (7.7 times shorter wall clock time) and less demanding (4.4 times less memory requirement) than an analytic Hessian. Capitalizing on the capabilities of parallel grid computing, NUMFREQ@Grid can outperform analytic methods in terms of wall time, memory requirements, and treatable system size. The NUMFREQ@Grid method presented herein demonstrates how grid computing can be used to facilitate embarrassingly parallel computational procedures and is a pioneer for future implementations.

Morphologic differentiation of colon carcinoma cell lines HT-29 and HT-29KM in rotating-wall vessels

NASA Technical Reports Server (NTRS)

Goodwin, T. J.; Jessup, J. M.; Wolf, D. A.

1992-01-01

A new low shear stress microcarrier culture system has been developed at NASA's Johnson Space Center that permits three-dimensional tissue culture. Two established human colon adenocarcinoma cell lines, HT-29, an undifferentiated, and HT-29KM, a stable, moderately differentiated subline of HT-29, were grown in new tissue culture bioreactors called Rotating-Wall Vessels (RWVs). RWVs are used in conjunction with multicellular cocultivation to develop a unique in vitro tissue modeling system. Cells were cultivated on Cytodex-3 microcarrier beads, with and without mixed normal human colonic fibroblasts, which served as the mesenchymal layer. Culture of the tumor lines in the absence of fibroblasts produced spheroidlike growth and minimal differentiation. In contrast, when tumor lines were co-cultivated with normal colonic fibroblasts, initial growth was confined to the fibroblast population until the microcarriers were covered. The tumor cells then commenced proliferation at an accelerated rate, organizing themselves into three-dimensional tissue masses that achieved 1.0- to 1.5-cm diameters. The masses displayed glandular structures, apical and internal glandular microvilli, tight intercellular junctions, desmosomes, cellular polarity, sinusoid development, internalized mucin, and structural organization akin to normal colon crypt development. Differentiated samples were subjected to transmission and scanning electron microscopy and histologic analysis, revealing embryoniclike mesenchymal cells lining the areas around the growth matrices. Necrosis was minimal throughout the tissue masses. These data suggest that the RWV affords a new model for investigation and isolation of growth, regulatory, and structural processes within neoplastic and normal tissue.

Intimal hyperplasia induced by vascular intervention causes lipoprotein retention and accelerated atherosclerosis.

PubMed

Kijani, Siavash; Vázquez, Ana Maria; Levin, Malin; Borén, Jan; Fogelstrand, Per

2017-07-01

Accelerated atherosclerosis diminishes the long term patency of vascular interventions, such as percutaneous coronary intervention and implantation of saphenous vein grafts. However, the cause of this accelerated atherosclerosis is unclear. In this study, we tested the hypothesis that intimal hyperplasia formed following vascular intervention promotes retention of atherogenic lipoproteins. Intimal hyperplasia was surgically induced in the mouse common carotid artery. The surgery was combined with different mouse models of hypercholesterolemia to obtain different cholesterol levels and to control the onsets of hypercholesterolemia. Three weeks after surgery, samples were immunostained for apoB lipoproteins, smooth muscle cells and leukocytes. Already at mild hypercholesterolemia (193 mg/dL), pronounced apoB lipoprotein retention was found in the extracellular matrix in both intimal hyperplasia and the injured underlying media. In contrast, minimal retention was detected in the uninjured proximal region of the same vessel, or in vessels from mice with normal cholesterol levels (81 mg/dL). Induction of aggravated hypercholesterolemia 3 weeks after surgery, when a mature intimal hyperplasia had been formed, caused a very rapid development of atherosclerotic lesions. Mechanistically, we show that lipoprotein retention was almost exclusively dependent on electrostatic interactions to proteoglycan glycosaminoglycans, and the lipoprotein retention to intimal hyperplasia could be inhibited in vivo using glycosaminoglycan-binding antibodies. Thus, formation of intimal hyperplasia following vascular intervention makes the vessel wall highly susceptible for lipoprotein retention and accelerated atherosclerosis. The increased lipoprotein retention in intimal hyperplasia can be targeted by blocking the interaction between apoB lipoproteins and glycosaminoglycans in the extracellular matrix. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

Upgraded PMI diagnostic capabilities using Accelerator-based In-situ Materials Surveillance (AIMS) on Alcator C-Mod

NASA Astrophysics Data System (ADS)

Kesler, Leigh; Barnard, Harold; Hartwig, Zachary; Sorbom, Brandon; Lanza, Richard; Terry, David; Vieira, Rui; Whyte, Dennis

2014-10-01

The AIMS diagnostic was developed to rapidly and non-invasively characterize in-situ plasma material interactions (PMI) in a tokamak. Recent improvements are described which significantly expand this measurement capability on Alcator C-Mod. The detection time at each wall location is reduced from about 10 min to 30 s, via improved hardware and detection geometry. Detectors are in an augmented re-entrant tube to maximize the solid angle between detectors and diagnostic locations. Spatial range is expanded by using beam dynamics simulation to design upgraded B-field power supplies to provide maximal poloidal access, including a ~20° toroidal range in the divertor. Measurement accuracy is improved with angular and energy resolved cross section measurements obtained using a separate 0.9 MeV deuteron ion accelerator. Future improvements include the installation of recessed scintillator tiles as beam targets for calibration of the diagnostic. Additionally, implanted depth marker tiles will enable AIMS to observe the in-situ erosion and deposition of high-Z plasma-facing materials. This work is supported by U.S. DOE Grant No. DE-FG02-94ER54235 and Cooperative Agreement No. DE-FC02-99ER54512.

A Three-Dimensional CFD Investigation of Secondary Flow in an Accelerating, 90 deg Elbow

NASA Technical Reports Server (NTRS)

Cavicchi, Richard H.

2001-01-01

NASA Glenn Research Center has recently applied the WIND National Code flow solver to an accelerating elbow with a 90 deg. bend to reveal aspects of secondary flow. This elbow was designed by NACA in the early 1950's such that flow separation would be avoided. Experimental testing was also done at that time. The current three dimensional CFD investigation shows that separation has indeed been avoided. Using its three-dimensional capability, this investigation provides various viewpoints in several planes that display the inception, development, and final location of a passage vortex. Its shape first becomes discernible as a vortex near the exit of the bend. This rendition of the exit passage vortex compares well with that found in the experiments. The viewpoints show that the passage vortex settles on the suction surface at the exit about one-third of the distance between the plane wall and midspan. Furthermore, it projects into the mainstream to about one-third of the channel width. Of several turbulence models used in this investigation, the Spalart Alimaras, Baldwin Lomax, and SST (Shear Stress Transport) models were by far the most successful in matching the experiments.

Experimental study on a heavy-gas cylinder accelerated by cylindrical converging shock waves

NASA Astrophysics Data System (ADS)

Si, T.; Zhai, Z.; Luo, X.; Yang, J.

2014-01-01

The Richtmyer-Meshkov instability behavior of a heavy-gas cylinder accelerated by a cylindrical converging shock wave is studied experimentally. A curved wall profile is well-designed based on the shock dynamics theory [Phys. Fluids, 22: 041701 (2010)] with an incident planar shock Mach number of 1.2 and a converging angle of in a mm square cross-section shock tube. The cylinder mixed with the glycol droplets flows vertically through the test section and is illuminated horizontally by a laser sheet. The images obtained only one per run by an ICCD (intensified charge coupled device) combined with a pulsed Nd:YAG laser are first presented and the complete evolution process of the cylinder is then captured in a single test shot by a high-speed video camera combined with a high-power continuous laser. In this way, both the developments of the first counter-rotating vortex pair and the second counter-rotating vortex pair with an opposite rotating direction from the first one are observed. The experimental results indicate that the phenomena induced by the converging shock wave and the reflected shock formed from the center of convergence are distinct from those found in the planar shock case.

Design of a ram accelerator mass launch system

NASA Technical Reports Server (NTRS)

Aarnio, Michael; Armerding, Calvin; Berschauer, Andrew; Christofferson, Erik; Clement, Paul; Gohd, Robin; Neely, Bret; Reed, David; Rodriguez, Carlos; Swanstrom, Fredrick

1988-01-01

The ram accelerator mass launch system has been proposed to greatly reduce the costs of placing acceleration-insensitive payloads into low earth orbit. The ram accelerator is a chemically propelled, impulsive mass launch system capable of efficiently accelerating relatively large masses from velocities of 0.7 km/sec to 10 km/sec. The principles of propulsion are based on those of a conventional supersonic air-breathing ramjet; however the device operates in a somewhat different manner. The payload carrying vehicle resembles the center-body of the ramjet and accelerates through a stationary tube which acts as the outer cowling. The tube is filled with premixed gaseous fuel and oxidizer mixtures that burn in the vicinity of the vehicle's base, producing a thrust which accelerates the vehicle through the tube. This study examines the requirement for placing a 2000 kg vehicle into a 500 km circular orbit with a minimum amount of on-board rocket propellant for orbital maneuvers. The goal is to achieve a 50 pct payload mass fraction. The proposed design requirements have several self-imposed constraints that define the vehicle and tube configurations. Structural considerations on the vehicle and tube wall dictate an upper acceleration limit of 1000 g's and a tube inside diameter of 1.0 m. In-tube propulsive requirements and vehicle structural constraints result in a vehicle diameter of 0.76 m, a total length of 7.5 m and a nose-cone half angle of 7 degrees. An ablating nose-cone constructed from carbon-carbon composite serves as the thermal protection mechanism for atmospheric transit.

Boundary layer development as a function of chamber pressure in the NASA Lewis 1030:1 area ratio rocket nozzle

NASA Technical Reports Server (NTRS)

Smith, Tamara A.

1988-01-01

Through the use of theoretical predictions of fluid properties and experimental heat transfer and thrust measurements, the zones of laminar, transitional, and turbulent boundary layer flow were defined for the NASA Lewis 1039:1 area ratio rocket nozzle. Tests were performed on the nozzle at chamber pressures from 350 to 100 psia. For these conditions, the throat diameter Reynolds numbers varied from 300,000 to 1 million. The propellants used were gaseous hydrogen and gaseous oxygen. Thrust measurements and nozzle outer wall temperature measurements were taken during the 3-sec test runs. Comparison of experimental heat transfer and thrust data with the corresponding predictions from the Two-Dimensional Kinetics (TDK) nozzle analysis program indicated laminar flow in the nozzle at a throat diameter Reynolds number of 320,000 or chamber pressure of 360 psia. Comparison of experimental and predicted heat transfer data indicated transitional flow up to and including a chamber pressure of 1000 psia. Predicted values of the axisymmetric acceleration parameter within the convergent and divergent nozzle were consistent with the above results. Based upon an extrapolation of the heat transfer data and predicted distributions of the axisymmetric acceleration parameter, transitional flow was predicted up to a throat diameter Reynolds number of 220,000 or 2600-psia chamber pressure. Above 2600-psia chamber pressure, fully developed turbulent flow was predicted.

Boundary layer development as a function of chamber pressure in the NASA Lewis 1030:1 area ratio rocket nozzle

NASA Technical Reports Server (NTRS)

Smith, Tamara A.

1988-01-01

Through the use of theoretical predictions of fluid properties and experimental heat transfer and thrust measurements, the zones of laminar, transitional, and turbulent boundary layer flow were defined for the NASA Lewis 1030:1 area ratio rocket nozzle. Tests were performed on the nozzle at chamber pressures from 350 to 100 psia. For these conditions, the throat diameter Reynolds numbers varied from 300,000 to 1 million. The propellants used were gaseous hydrogen and gaseous oxygen. Thrust measurements and nozzle outer wall temperature measurements were taken during the 3-sec test runs. Comparison of experimental heat transfer and thrust data with the corresponding predictions from the Two-Dimensional Kinetics (TDK) nozzle analysis program indicated laminar flow in the nozzle at a throat diameter Reynolds number of 320,000 or chamber pressure of 360 psia. Comparison of experimental and predicted heat transfer data indicated transitional flow up to and including a chamber pressure of 1000 psia. Predicted values of the axisymmetric acceleration parameter within the convergent and divergent nozzle were consistent with the above results. Based upon an extrapolation of the heat transfer data and predicted distributions of the axisymmetric acceleration parameter, transitional flow was predicted up to a throat diameter Reynolds number of 220,000 or 2600-psia chamber pressure. Above 2600-psia chamber pressure, fully developed turbulent flow was predicted.

Investigation of using shrinking method in construction of Institute for Research in Fundamental Sciences Electron Linear Accelerator TW-tube (IPM TW-Linac tube)

NASA Astrophysics Data System (ADS)

Ghasemi, F.; Abbasi Davani, F.

2015-06-01

Due to Iran's growing need for accelerators in various applications, IPM's electron Linac project has been defined. This accelerator is a 15 MeV energy S-band traveling-wave accelerator which is being designed and constructed based on the klystron that has been built in Iran. Based on the design, operating mode is π /2 and the accelerating chamber consists of two 60cm long tubes with constant impedance and a 30cm long buncher. Amongst all construction methods, shrinking method is selected for construction of IPM's electron Linac tube because it has a simple procedure and there is no need for large vacuum or hydrogen furnaces. In this paper, different aspects of this method are investigated. According to the calculations, linear ratio of frequency alteration to radius change is 787.8 MHz/cm, and the maximum deformation at the tube wall where disks and the tube make contact is 2.7μ m. Applying shrinking method for construction of 8- and 24-cavity tubes results in satisfactory frequency and quality factor. Average deviations of cavities frequency of 8- and 24-cavity tubes to the design values are 0.68 MHz and 1.8 MHz respectively before tune and 0.2 MHz and 0.4 MHz after tune. Accelerating tubes, buncher, and high power couplers of IPM's electron linac are constructed using shrinking method.

Apollo oxygen tank stratification analysis, volume 2

NASA Technical Reports Server (NTRS)

Barton, J. E.; Patterson, H. W.

1972-01-01

An analysis of flight performance of the Apollo 15 cryogenic oxygen tanks was conducted with the variable grid stratification math model developed earlier in the program. Flight conditions investigated were the CMP-EVA and one passive thermal control period which exhibited heater temperature characteristics not previously observed. Heater temperatures for these periods were simulated with the math model using flight acceleration data. Simulation results (heater temperature and tank pressure) compared favorably with the Apollo 15 flight data, and it was concluded that tank performance was nominal. Math model modifications were also made to improve the simulation accuracy. The modifications included the addition of the effects of the tank wall thermal mass and an improved system flow distribution model. The modifications improved the accuracy of simulated pressure response based on comparisons with flight data.

Predicting, examining, and evaluating FAC in US power plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cohn, M.J.; Garud, Y.S.; Raad, J. de

1999-11-01

There have been many pipe failures in fossil and nuclear power plant piping systems caused by flow-accelerated corrosion (FAC). In some piping systems, this failure mechanism maybe the most important type of damage to mitigate because FAC damage has led to catastrophic failures and fatalities. Detecting the damage and mitigating the problem can significantly reduce future forced outages and increase personnel safety. This article discusses the implementation of recent developments to select FAC inspection locations, perform cost-effective examinations, evaluate results, and mitigate FAC failures. These advances include implementing the combination of software to assist in selecting examination locations and anmore » improved pulsed eddy current technique to scan for wall thinning without removing insulation. The use of statistical evaluation methodology and possible mitigation strategies also are discussed.« less

Acoustic nonreciprocity in Coriolis mean flow systems.

PubMed

Naghdi, Masoud; Farzbod, Farhad

2018-01-01

One way to break acoustic reciprocity is to have a moving wave propagation medium. If the acoustic wave vector and the moving fluid velocity are collinear, the wave vector shift caused by the fluid flow can be used to break. In this paper, an alternative approach is investigated in which the fluid velocity enters the differential equation of the system as a cross product term with the wave vector. A circular field where the fluid velocity increases radially has a Coriolis acceleration term. In such a system, the acoustic wave enters from the central wall and exits from the perimeter wall. In this paper, the differential equation is solved numerically and the effect of fluid velocity on the nonreciprocity factor is examined.

Investigation of charge dissipation in jet fuel in a dielectric fuel tank

NASA Astrophysics Data System (ADS)

Kitanin, E. L.; Kravtsov, P. A.; Trofimov, V. A.; Kitanina, E. E.; Bondarenko, D. A.

2017-09-01

The electrostatic charge dissipation process in jet fuel in a polypropylene tank was investigated experimentally. Groundable metallic terminals were installed in the tank walls to accelerate the dissipation process. Several sensors and an electrometer with a current measuring range from 10-11 to 10-3 A were specifically designed to study the dissipation rates. It was demonstrated that thanks to the sensors and the electrometer one can obtain reliable measurements of the dissipation rate and look at how it is influenced by the number and locations of the terminals. Conductivity of jet fuel and effective conductivity of the tank walls were investigated in addition. The experimental data agree well with the numerical simulation results obtained using COMSOL software package.

Evaporation Source for Deposition of Protective Layers inside Tubes

NASA Astrophysics Data System (ADS)

Musa, Geavit; Mustata, Ion; Dinescu, Gheorghe; Bajeu, George; Raiciu, Elena

1992-09-01

A heated cathode arc can be ignited in vacuum in the vapours of the anode material due to the accelerated electron beam from the cathode. A small assembly, consisting of an electron gun as the cathode and a refractory metal crucible, containing the material to be evaporated, as the anode, can be moved along the axis of the tube whose inside wall is to be covered with a protective layer. The vacuum arc ignited between the electrodes in the vapours of the evaporating anode material ensures a high deposition rate with low thermal energy transport to the tube wall. This new method can be used for the deposition of various metal layers inside different kinds of tubes (metallic, glass, ceramics or plastics).

Rotating field mass and velocity analyzer

NASA Technical Reports Server (NTRS)

Smith, Steven Joel (Inventor); Chutjian, Ara (Inventor)

1998-01-01

A rotating field mass and velocity analyzer having a cell with four walls, time dependent RF potentials that are applied to each wall, and a detector. The time dependent RF potentials create an RF field in the cell which effectively rotates within the cell. An ion beam is accelerated into the cell and the rotating RF field disperses the incident ion beam according to the mass-to-charge (m/e) ratio and velocity distribution present in the ion beam. The ions of the beam either collide with the ion detector or deflect away from the ion detector, depending on the m/e, RF amplitude, and RF frequency. The detector counts the incident ions to determine the m/e and velocity distribution in the ion beam.

Seismic performance evaluation of RC frame-shear wall structures using nonlinear analysis methods

NASA Astrophysics Data System (ADS)

Shi, Jialiang; Wang, Qiuwei

To further understand the seismic performance of reinforced concrete (RC) frame-shear wall structures, a 1/8 model structure is scaled from a main factory structure with seven stories and seven bays. The model with four-stories and two-bays was pseudo-dynamically tested under six earthquake actions whose peak ground accelerations (PGA) vary from 50gal to 400gal. The damage process and failure patterns were investigated. Furthermore, nonlinear dynamic analysis (NDA) and capacity spectrum method (CSM) were adopted to evaluate the seismic behavior of the model structure. The top displacement curve, story drift curve and distribution of hinges were obtained and discussed. It is shown that the model structure had the characteristics of beam-hinge failure mechanism. The two methods can be used to evaluate the seismic behavior of RC frame-shear wall structures well. What’s more, the NDA can be somewhat replaced by CSM for the seismic performance evaluation of RC structures.

Pulsed electron beam propagation in gases under pressure of 6.6 kPa in drift tube

NASA Astrophysics Data System (ADS)

Kholodnaya, G. E.; Sazonov, R. V.; Ponomarev, D. V.; Remnev, G. E.; Poloskov, A. V.

2017-02-01

This paper presents the results of an investigation of pulsed electron beam transport propagated in a drift tube filled with different gases (He, H2, N2, Ar, SF6, and CO2). The total pressure in the drift tube was 6.6 kPa. The experiments were carried out using a TEA-500 pulsed electron accelerator. The electron beam was propagated in the drift tube composed of two sections equipped with reverse current shunts. Under a pressure of 6.6 kPa, the maximum value of the electron beam charge closed on the walls of the drift tube was recorded when the beam was propagated in hydrogen and carbon dioxide. The minimum value of the electron beam charge closed on the walls of the drift tube was recorded for sulfur hexafluoride. The visualization of the pulsed electron beam energy losses onto the walls of the drift chamber was carried out using radiation-sensitive film.

Production of hard X rays in a plasma focus

NASA Technical Reports Server (NTRS)

Newman, C. E.; Petrosian, V.

1975-01-01

A model of a plasma focus is examined wherein large axial electric fields are produced by an imploding current sheet during the final nanoseconds of the collapse phase and where the fields provide a mechanism for creating a beam of electrons of highly suprathermal energies. The expected bremsstrahlung radiation above 100 keV is calculated for such a beam, which has a power-law spectrum, both from electron-deuteron collisions in the focused plasma and when the beam reaches the wall of the device. It is concluded that, since the experimental results indicate little or no radiation above 100 keV originating in the walls, that the electrons in the beam must be decelerated after leaving the plasma and before reaching the wall. Comparisons with the results and the total energy of the device yield qualitative agreement with the expected angular distribution of hard X-rays and reasonable agreement with the total energy in accelerated electrons required to produce the observed total energy in hard X-rays by this mechanism.

An experimental investigation of velocity fields in divergent glottal models of the human vocal tract

NASA Astrophysics Data System (ADS)

Erath, Byron D.; Plesniak, Michael W.

2005-09-01

In speech, sound production arises from fluid-structure interactions within the larynx as well as viscous flow phenomena that is most likely to occur during the divergent orientation of the vocal folds. Of particular interest are the flow mechanisms that influence the location of flow separation points on the vocal folds walls. Physiologically scaled pulsatile flow fields in 7.5 times real size static divergent glottal models were investigated. Three divergence angles were investigated using phase-averaged particle image velocimetry (PIV). The pulsatile glottal jet exhibited a bi-modal stability toward both glottal walls, although there was a significant amount of variance in the angle the jet deflected from the midline. The attachment of the Coanda effect to the glottal model walls occurred when the pulsatile velocity was a maximum, and the acceleration of the waveform was zero. The location of the separation and reattachment points of the flow from the glottal models was a function of the velocity waveform and divergence angle. Acoustic analogies show that a dipole sound source contribution arising from the fluid interaction (Coanda jet) with the vocal fold walls is expected. [Work funded by NIH Grant RO1 DC03577.

Corrosion monitoring on a large steel pressure vessel by thin-layer activation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wallace, G.; Boulton, L.H.; Hodder, D.

1989-12-01

Thin-layer activation (TLA) is a technique in which a surface is irradiated by a nuclear accelerator and thereby labeled with an accurate depth profile of low-level radioactivity. By monitoring this activity it is possible to calculate how much of that surface has been removed by corrosion. As the radioactivity is marked by the emission of penetrating gamma rays, it is possible to monitor this corrosion remotely through several centimeters of steel. This technique has been used to monitor erosion-corrosion occurring on the inner carbon steel wall of a continuous Kraft pulp digester at a paper mill. Representative coupons of themore » same steel as the digester wall were irradiated and fixed to the walls in the liquor extraction zone during a maintenance shutdown. The loss of metal over the six months was measured by external monitoring of gamma radiation through the vessel wall, and converted to a corrosion rate. Subsequent weight-loss measurements and comparison with ultrasonic thickness measurements established that the corrosion rate measured gave accurate results over a much shorter time scale. TLA thus enables current, rather than historical corrosion rates to be measured in a large steel pressure vessel.« less

VqDUF642, a gene isolated from the Chinese grape Vitis quinquangularis, is involved in berry development and pathogen resistance.

PubMed

Xie, Xiaoqing; Wang, Yuejin

2016-11-01

The DUF642 gene VqDUF642 , isolated from the Chinese grape species V. quinquangularis accession Danfeng-2, participates in berry development and defense responses against Erysiphe necator and Botrytis cinerea. The proteins with domains of unknown function 642 (DUF642) comprise a large protein family according to cell wall proteomic analyses in plants. However, the works about functional characterization of DUF642s in plant development and resistance to pathogens are scarce. In this study, a gene encoding a DUF642 protein was isolated from Chinese grape V. quinquangularis accession Danfeng-2, and designated as VqDUF642. Its full-length cDNA contains a 1107-bp open reading frame corresponding to a deduced 368-amino acid protein. Multiple sequence alignments and phylogenetic analysis showed that VqDUF642 is highly homologous to one of the DUF642 proteins (VvDUF642) in V. vinifera. The VqDUF642 was localized to the cell wall of tobacco epidermal cells. Accumulation of VqDUF642 protein and VqDUF642 transcript abundance increased at the later stage of grape berry development in Danfeng-2. Overexpression of VqDUF642 in transgenic tomato plants accelerated plant growth and reduced susceptibility to Botrytis cinerea. Transgenic Thompson Seedless grapevine plants overexpressing VqDUF642 exhibited enhanced resistance to Erysiphe necator and B. cinerea. Moreover, VqDUF642 overexpression affected the expression of a couple of pathogenesis-related (PR) genes in transgenic tomato and grapevine upon pathogen inoculation. Taken together, these results suggest that VqDUF642 is involved in plant development and defense against pathogenic infections.

Self-Calibrating Wave-Encoded Variable-Density Single-Shot Fast Spin Echo Imaging.

PubMed

Chen, Feiyu; Taviani, Valentina; Tamir, Jonathan I; Cheng, Joseph Y; Zhang, Tao; Song, Qiong; Hargreaves, Brian A; Pauly, John M; Vasanawala, Shreyas S

2018-04-01

It is highly desirable in clinical abdominal MR scans to accelerate single-shot fast spin echo (SSFSE) imaging and reduce blurring due to T 2 decay and partial-Fourier acquisition. To develop and investigate the clinical feasibility of wave-encoded variable-density SSFSE imaging for improved image quality and scan time reduction. Prospective controlled clinical trial. With Institutional Review Board approval and informed consent, the proposed method was assessed on 20 consecutive adult patients (10 male, 10 female, range, 24-84 years). A wave-encoded variable-density SSFSE sequence was developed for clinical 3.0T abdominal scans to enable high acceleration (3.5×) with full-Fourier acquisitions by: 1) introducing wave encoding with self-refocusing gradient waveforms to improve acquisition efficiency; 2) developing self-calibrated estimation of wave-encoding point-spread function and coil sensitivity to improve motion robustness; and 3) incorporating a parallel imaging and compressed sensing reconstruction to reconstruct highly accelerated datasets. Image quality was compared pairwise with standard Cartesian acquisition independently and blindly by two radiologists on a scale from -2 to 2 for noise, contrast, confidence, sharpness, and artifacts. The average ratio of scan time between these two approaches was also compared. A Wilcoxon signed-rank tests with a P value under 0.05 considered statistically significant. Wave-encoded variable-density SSFSE significantly reduced the perceived noise level and improved the sharpness of the abdominal wall and the kidneys compared with standard acquisition (mean scores 0.8, 1.2, and 0.8, respectively, P < 0.003). No significant difference was observed in relation to other features (P = 0.11). An average of 21% decrease in scan time was achieved using the proposed method. Wave-encoded variable-density sampling SSFSE achieves improved image quality with clinically relevant echo time and reduced scan time, thus providing a fast and robust approach for clinical SSFSE imaging. 1 Technical Efficacy: Stage 6 J. Magn. Reson. Imaging 2018;47:954-966. © 2017 International Society for Magnetic Resonance in Medicine.

New Method Developed To Purify Single Wall Carbon Nanotubes for Aerospace Applications

NASA Technical Reports Server (NTRS)

Lebron, Marisabel; Meador, Michael A.

2003-01-01

Single wall carbon nanotubes have attracted considerable attention because of their remarkable mechanical properties and electrical and thermal conductivities. Use of these materials as primary or secondary reinforcements in polymers or ceramics could lead to new materials with significantly enhanced mechanical strength and electrical and thermal conductivity. Use of carbon-nanotube-reinforced materials in aerospace components will enable substantial reductions in component weight and improvements in durability and safety. Potential applications for single wall carbon nanotubes include lightweight components for vehicle structures and propulsion systems, fuel cell components (bipolar plates and electrodes) and battery electrodes, and ultra-lightweight materials for use in solar sails. A major barrier to the successful use of carbon nanotubes in these components is the need for methods to economically produce pure carbon nanotubes in large enough quantities to not only evaluate their suitability for certain applications but also produce actual components. Most carbon nanotube synthesis methods, including the HiPCO (high pressure carbon monoxide) method developed by Smalley and others, employ metal catalysts that remain trapped in the final product. These catalyst impurities can affect nanotube properties and accelerate their decomposition. The development of techniques to remove most, if not all, of these impurities is essential to their successful use in practical applications. A new method has been developed at the NASA Glenn Research Center to purify gram-scale quantities of single wall carbon nanotubes. This method, a modification of a gas phase purification technique previously reported by Smalley and others, uses a combination of high-temperature oxidations and repeated extractions with nitric and hydrochloric acid. This improved procedure significantly reduces the amount of impurities (catalyst and nonnanotube forms of carbon) within the nanotubes, increasing their stability significantly. The onset of decomposition of the purified nanotubes (determined by thermal gravimetric analysis in air) is more than 300 C higher than that of the crude nanotubes. Transmission electron microscopy analysis of nanotubes purified by this method reveals near complete removal of iron catalyst particles. Analysis of the nanotubes using inductively coupled plasma spectroscopy revealed that the iron content of the nanotubes was reduced from 22.7 wt% in the crude nanotubes to less than 0.02 wt%. X-ray photoelectron spectroscopy revealed a decrease in iron content after purification as well as an increase in oxygen content due to the formation of carboxylic acid groups on the surface of the nanotubes. Nanotubes purified by this improved method can be readily dispersed in common organic solvents, in particular N,N-dimethylformamide, using prolonged ultrasonic treatment. These dispersions can then be used to incorporate single wall carbon nanotubes into polymer films.

Cell Wall Composition and Candidate Biosynthesis Gene Expression During Rice Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, Fan; Manisseri, Chithra; Fagerström, Alexandra

Cell walls of grasses, including cereal crops and biofuel grasses, comprise the majority of plant biomass and intimately influence plant growth, development and physiology. However, the functions of many cell wall synthesis genes, and the relationships among and the functions of cell wall components remain obscure. To better understand the patterns of cell wall accumulation and identify genes that act in grass cell wall biosynthesis, we characterized 30 samples from aerial organs of rice (Oryza sativa cv. Kitaake) at 10 developmental time points, 3-100 d post-germination. Within these samples, we measured 15 cell wall chemical components, enzymatic digestibility and 18more » cell wall polysaccharide epitopes/ligands. We also used quantitative reverse transcription-PCR to measure expression of 50 glycosyltransferases, 15 acyltransferases and eight phenylpropanoid genes, many of which had previously been identified as being highly expressed in rice. Most cell wall components vary significantly during development, and correlations among them support current understanding of cell walls. We identified 92 significant correlations between cell wall components and gene expression and establish nine strong hypotheses for genes that synthesize xylans, mixed linkage glucan and pectin components. This work provides an extensive analysis of cell wall composition throughout rice development, identifies genes likely to synthesize grass cell walls, and provides a framework for development of genetically improved grasses for use in lignocellulosic biofuel production and agriculture.« less

Experimental perfect-gas study of expansion-tube flow characteristics

NASA Technical Reports Server (NTRS)

Shinn, J. L.; Miller, C. G., III

1978-01-01

Results of an experimental investigation of expansion tube flow characteristics performed with helium test gas and acceleration gas are presented. The use of helium, eliminates complex real gas chemistry in the comparison of measured and predicted flow quantities. The driver gas was unheated helium at a nominal pressure of 33 MN sq m. The quiescent test gas pressure and quiescent acceleration gas pressure were varied from 0.7 to 50 kN/sq m and from 2.5 to 53 N/sq m, respectively. The effects of tube-wall boundary layer growth and finite secondary diaphragm opening time were examined through the variation of the quiescent gas pressures and secondary diaphragm thickness. Optimum operating conditions for helium test gas were also defined.

76 FR 33305 - Medicare Program; Accelerated Development Sessions for Accountable Care Organizations-June 20, 21...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-08

... as accelerated development sessions (ADSs) instead of accelerated development learning sessions... Sessions'' is corrected to read ``Accelerated Development Learning Sessions''. (2) In the SUMMARY, the... first of four accelerated development learning sessions (ADLSs) that will provide executives with the...

POE/PLGA composite microspheres: formation and in vitro behavior of double walled microspheres.

PubMed

Yang, Yi-Yan; Shi, Meng; Goh, Suat-Hong; Moochhala, Shabbir M; Ng, Steve; Heller, Jorge

2003-03-07

The poly(ortho ester) (POE) and poly(D,L-lactide-co-glycolide) 50:50 (PLGA) composite microspheres were fabricated by a water-in-oil-in-water (w/o/w) double emulsion process. The morphology of the composite microspheres varied depending on POE content. When the POE content was 50, 60 or 70% in weight, the double walled microspheres with a dense core of POE and a porous shell of PLGA were formed. The formation of the double walled POE/PLGA microspheres was analysed. Their in vitro degradation behavior was characterized by scanning electron microscopy, gel permeation chromatography, Fourier-transform infrared microscopy and nuclear magnetic resonance spectroscopy (NMR). It was found that compared to the neat POE or PLGA microspheres, distinct degradation mechanism was achieved in the double walled POE/PLGA microspheres system. The degradation of the POE core was accelerated due to the acidic microenvironment produced by the hydrolysis of the outer PLGA layer. The formation of hollow microspheres became pronounced after the first week in vitro. 1H NMR spectra showed that the POE core was completely degraded after 4 weeks. On the other hand, the outer PLGA layer experienced slightly retarded degradation after the POE core disappeared. PLGA in the double walled microspheres kept more than 32% of its initial molecular weight over a period of 7 weeks.

Ultra-fast Escape of a Octopus-inspired Rocket

NASA Astrophysics Data System (ADS)

Weymouth, Gabriel; Triantafyllou, Michael

2013-11-01

The octopus, squid, and other cephalopods inflate with water and then release a jet to accelerate in the opposite direction. This escape mechanism is particularly interesting in the octopus because they become initially quite bluff, yet this does not hinder them in achieving impressive bursts of speed. We examine this somewhat paradoxical maneuver using a simple deflating spheroid model in both potential and viscous flow. We demonstrate that the dynamic reduction of the width of the body completely changes the flow and forces acting on the escaping rocket in three ways. First, a body which reduces in size can generate an added mass thrust which counteracts the added mass inertia. Second, the motion of the shrinking wall acts similar to suction on a static wall, reducing separation and drag forces in a viscous fluid, but that this effects depends on the rate of size change. Third, using a combination of these two features it is possible to initially load the fluid with kinetic energy when heavy and bluff and then recover that energy when streamlined and light, enabling ultra-fast accelerations. As a notable example, these mechanisms allow a shrinking spheroid rocket in a heavy inviscid fluid to achieve speeds greater than an identical rocket in the vacuum of space. Southampton Marine and Maritime Institute.

Models, assumptions, and experimental tests of flows near boundaries in magnetized plasmas

NASA Astrophysics Data System (ADS)

Siddiqui, M. Umair; Thompson, Derek S.; Jackson, Cory D.; Kim, Justin F.; Hershkowitz, Noah; Scime, Earl E.

2016-05-01

We present the first measurements of ion flows in three dimensions (3Ds) using laser-induced fluorescence in the plasma boundary region. Measurements are performed upstream from a grounded stainless steel limiter plate at various angles ( ψ=16 ° to 80 ° ) to the background magnetic field in two argon helicon experiments (MARIA at the University of Wisconsin-Madison and HELIX at West Virginia University). The Chodura magnetic presheath model for collisionless plasmas [R. Chodura, Phys. Fluids 25, 1628 (1982)] is shown to be inaccurate for systems with sufficient ion-neutral collisions and ionization such as tokamak scrape off layers. A 3D ion fluid model that accounts for ionization and charge-exchange collisions is found to accurately describe the measured ion flows in regions where the ion flux tubes do not intersect the boundary. Ion acceleration in the E →×B → direction is observed within a few ion Larmor radii of the grounded plate for ψ=80 ° . We argue that fully 3D ion and neutral acceleration in the plasma boundary are uniquely caused by the long-range presheath electric fields, and that models that omit presheath effects under-predict observed wall erosion in tokamak divertors and Hall thruster channel walls.

Predicting induced radioactivity for the accelerator operations at the Taiwan Photon Source.

PubMed

Sheu, R J; Jiang, S H

2010-12-01

This study investigates the characteristics of induced radioactivity due to the operations of a 3-GeV electron accelerator at the Taiwan Photon Source (TPS). According to the beam loss analysis, the authors set two representative irradiation conditions for the activation analysis. The FLUKA Monte Carlo code has been used to predict the isotope inventories, residual activities, and remanent dose rates as a function of time. The calculation model itself is simple but conservative for the evaluation of induced radioactivity in a light source facility. This study highlights the importance of beam loss scenarios and demonstrates the great advantage of using FLUKA in comparing the predicted radioactivity with corresponding regulatory limits. The calculated results lead to the conclusion that, due to fairly low electron consumption, the radioactivity induced in the accelerator components and surrounding concrete walls of the TPS is rather moderate and manageable, while the possible activation of air and cooling water in the tunnel and their environmental releases are negligible.

Direct measurement of the image displacement instability in a linear induction accelerator

NASA Astrophysics Data System (ADS)

Burris-Mog, T. J.; Ekdahl, C. A.; Moir, D. C.

2017-06-01

The image displacement instability (IDI) has been measured on the 20 MeV Axis I of the dual axis radiographic hydrodynamic test facility and compared to theory. A 0.23 kA electron beam was accelerated across 64 gaps in a low solenoid focusing field, and the position of the beam centroid was measured to 34.3 meters downstream from the cathode. One beam dynamics code was used to model the IDI from first principles, while another code characterized the effects of the resistive wall instability and the beam break-up (BBU) instability. Although the BBU instability was not found to influence the IDI, it appears that the IDI influences the BBU. Because the BBU theory does not fully account for the dependence on beam position for coupling to cavity transverse magnetic modes, the effect of the IDI is missing from the BBU theory. This becomes of particular concern to users of linear induction accelerators operating in or near low magnetic guide fields tunes.

Direct measurement of the image displacement instability in a linear induction accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burris-Mog, T. J.; Ekdahl, C. A.; Moir, D. C.

The image displacement instability (IDI) has been measured on the 20 MeV Axis I of the dual axis radiographic hydrodynamic test facility and compared to theory. A 0.23 kA electron beam was accelerated across 64 gaps in a low solenoid focusing field, and the position of the beam centroid was measured to 34.3 meters downstream from the cathode. One beam dynamics code was used to model the IDI from first principles, while another code characterized the effects of the resistive wall instability and the beam break-up (BBU) instability. Although the BBU instability was not found to influence the IDI, itmore » appears that the IDI influences the BBU. Because the BBU theory does not fully account for the dependence on beam position for coupling to cavity transverse magnetic modes, the effect of the IDI is missing from the BBU theory. Finally, this becomes of particular concern to users of linear induction accelerators operating in or near low magnetic guide fields tunes.« less

Direct measurement of the image displacement instability in a linear induction accelerator

DOE PAGES

Burris-Mog, T. J.; Ekdahl, C. A.; Moir, D. C.

2017-06-19

The image displacement instability (IDI) has been measured on the 20 MeV Axis I of the dual axis radiographic hydrodynamic test facility and compared to theory. A 0.23 kA electron beam was accelerated across 64 gaps in a low solenoid focusing field, and the position of the beam centroid was measured to 34.3 meters downstream from the cathode. One beam dynamics code was used to model the IDI from first principles, while another code characterized the effects of the resistive wall instability and the beam break-up (BBU) instability. Although the BBU instability was not found to influence the IDI, itmore » appears that the IDI influences the BBU. Because the BBU theory does not fully account for the dependence on beam position for coupling to cavity transverse magnetic modes, the effect of the IDI is missing from the BBU theory. Finally, this becomes of particular concern to users of linear induction accelerators operating in or near low magnetic guide fields tunes.« less

Carbon-containing compounds on fusion-related surfaces: Thermal and ion-induced formation and erosion

NASA Astrophysics Data System (ADS)

Linsmeier, Christian

2004-12-01

The deposition of carbon on metals is the unavoidable consequence of the application of different wall materials in present and future fusion experiments like ITER. Presently used and prospected materials besides carbon (CFC materials in high heat load areas) are tungsten and beryllium. The simultaneous application of different materials leads to the formation of surface compounds due to the erosion, transport and re-deposition of material during plasma operations. The formation and erosion processes are governed by widely varying surface temperatures and kinetic energies as well as the spectrum of impinging particles from the plasma. The knowledge of the dependence on these parameters is crucial for the understanding and prediction of the compound formation on wall materials. The formation of surface layers is of great importance, since they not only determine erosion rates, but also influence the ability of the first wall for hydrogen isotope inventory accumulation and release. Surface compound formation, diffusion and erosion phenomena are studied under well-controlled ultra-high vacuum conditions using in-situ X-ray photoelectron spectroscopy (XPS) and ion beam analysis techniques available at a 3 MV tandem accelerator. XPS provides chemical information and allows distinguishing elemental and carbidic phases with high surface sensitivity. Accelerator-based spectroscopies provide quantitative compositional analysis and sensitivity for deuterium in the surface layers. Using these techniques, the formation of carbidic layers on metals is studied from room temperature up to 1700 K. The formation of an interfacial carbide of several monolayers thickness is not only observed for metals with exothermic carbide formation enthalpies, but also in the cases of Ni and Fe which form endothermic carbides. Additional carbon deposited at 300 K remains elemental. Depending on the substrate, carbon diffusion into the bulk starts at elevated temperatures together with additional carbide formation. Depending on the bond nature in the carbide (metallic in the transition metal carbides, ionic e.g. in Be2C), the surface carbide layer is dissolved upon further increased temperatures or remains stable. Carbide formation can also be initiated by ion bombardment, both of chemically inert noble gas ions or C+ or CO+ ions. In the latter case, a deposition-erosion equilibrium develops which leads to a ternary surface layer of constant thickness. A chemical erosion channel is also discussed for the enhanced erosion of thin carbon films on metals by deuterium ions.

Increased Airway Wall Thickness is Associated with Adverse Longitudinal First-Second Forced Expiratory Volume Trajectories of Former World Trade Center workers.

PubMed

de la Hoz, Rafael E; Liu, Xiaoyu; Doucette, John T; Reeves, Anthony P; Bienenfeld, Laura A; Wisnivesky, Juan P; Celedón, Juan C; Lynch, David A; San José Estépar, Raúl

2018-05-24

Occupational exposures at the WTC site after September 11, 2001 have been associated with several presumably inflammatory lower airway diseases. In this study, we describe the trajectories of expiratory air flow decline, identify subgroups with adverse progression, and investigate the association of a quantitative computed tomography (QCT) imaging measurement of airway wall thickness, and other risk factors for adverse progression. We examined the trajectories of expiratory air flow decline in a group of 799 former WTC workers and volunteers with QCT-measured (with two independent systems) wall area percent (WAP) and at least 3 periodic spirometries. We calculated individual regression lines for first-second forced expiratory volume (FEV 1 ), identified subjects with rapidly declining and increasing ("gainers"), and compared them to subjects with normal and "stable" FEV 1 decline. We used multivariate logistic regression to model decliner vs. stable trajectories. The mean longitudinal FEV 1 slopes for the entire study population, and its stable, decliner, and gainer subgroups were, respectively, - 35.8, - 8, - 157.6, and + 173.62 ml/year. WAP was associated with "decliner" status (OR adj 1.08, 95% CI 1.02, 1.14, per 5% increment) compared to stable. Age, weight gain, baseline FEV 1 percent predicted, bronchodilator response, and pre-WTC occupational exposures were also significantly associated with accelerated FEV 1 decline. Analyses of gainers vs. stable subgroup showed WAP as a significant predictor in unadjusted but not consistently in adjusted analyses. The apparent normal age-related rate of FEV 1 decline results from averaging widely divergent trajectories. WAP is significantly associated with accelerated air flow decline in WTC workers.

Functionalization of single-walled carbon nanotubes regulates their effect on hemostasis

NASA Astrophysics Data System (ADS)

Sokolov, A. V.; Aseychev, A. V.; Kostevich, V. A.; Gusev, A. A.; Gusev, S. A.; Vlasova, I. I.

2011-04-01

Applications of single-walled carbon nanotubes (SWNTs) in medical field imply the use of drug-coupled carbon nanotubes as well as carbon nanotubes functionalized with different chemical groups that change nanotube surface properties and interactions between nanotubes and cells. Covalent attachment of polyethylene glycol (PEG) to carboxylated single-walled carbon nanotubes (c-SWNT) is known to prevent the nanotubes from interaction with macrophages. Here we characterized nanotube's ability to stimulate coagulation processes in platelet-poor plasma (PPP), and evaluated the effect of SWNTs on platelet aggregation in platelet-rich plasma (PRP). Our study showed that PEG-SWNT did not affect the rate of clotting in PPP, while c-SWNT shortened the clot formation time five times compared to the control PPP. Since c-SWNT failed to accelerate coagulation in plasma lacking coagulation factor XI, it may be suggested that c-SWNT affects the contact activation pathway. In PRP, platelets responded to both SWNT types with irreversible aggregation, as evidenced by changes in the aggregate mean radius. However, the rate of aggregation induced by c-SWNT was two times higher than it was with PEG-SWNT. Cytological analysis also showed that c-SWNT was two times more efficient when compared to PEG-SWNT in aggregating platelets in PRP. Taken together, our results show that functionalization of nanoparticles can diminish their negative influence on blood cells. As seen from our data, modification of c-SWNT with PEG, when only a one percent of carbon atoms is bound to polymer (70 wt %), decreased the nanotube-induced coagulation in PRP and repelled the accelerating effect on the coagulation in PPP. Thus, when functionalized SWNTs are used for administration into bloodstream of laboratory animals, their possible pro-coagulant and pro-aggregating properties must be taken into account.

Impact of the resistive wall impedance on beam dynamics in the Future Circular e+e- Collider

NASA Astrophysics Data System (ADS)

Migliorati, M.; Belli, E.; Zobov, M.

2018-04-01

The Future Circular Collider study, which aims at designing post-LHC particle accelerator options, is entering in the final stage, which foresees a conceptual design report containing the basic requirements for a hadron and a lepton collider, as well as options for an electron-proton machine. Due to the high beam intensities of these accelerators, collective effects have to be carefully analyzed. Among them, the finite conductivity of the beam vacuum chamber represents a major source of impedance for the electron-positron collider. By using numerical and analytical tools, a parametric study of longitudinal and transverse instabilities caused by the resistive wall is performed in this paper for the case of the Future Circular Collider lepton machine, by taking into account also the effects of coating, used to fight the electron cloud build up. It will be proved that under certain assumptions the coupling impedance of a two layer system does not depend on the conductivity of the coating and this property represents an important characteristic for the choice of the material itself. The results and findings of this study have an impact on the machine design in several aspects. In particular the quite low threshold of single bunch instabilities with respect to the nominal beam current and the not negligible power losses due to the resistive wall are shown, together with the necessity of a new feedback system to counteract the fast transverse coupled bunch instability. The importance of a round vacuum chamber to avoid the quadrupolar tune shift is also discussed. Finally the crucial importance of the beam pipe material coating and thickness choice for the above results is underlined.

Understanding the fluid mechanics behind transverse wall shear stress.

PubMed

Mohamied, Yumnah; Sherwin, Spencer J; Weinberg, Peter D

2017-01-04

The patchy distribution of atherosclerosis within arteries is widely attributed to local variation in haemodynamic wall shear stress (WSS). A recently-introduced metric, the transverse wall shear stress (transWSS), which is the average over the cardiac cycle of WSS components perpendicular to the temporal mean WSS vector, correlates particularly well with the pattern of lesions around aortic branch ostia. Here we use numerical methods to investigate the nature of the arterial flows captured by transWSS and the sensitivity of transWSS to inflow waveform and aortic geometry. TransWSS developed chiefly in the acceleration, peak systolic and deceleration phases of the cardiac cycle; the reverse flow phase was too short, and WSS in diastole was too low, for these periods to have a significant influence. Most of the spatial variation in transWSS arose from variation in the angle by which instantaneous WSS vectors deviated from the mean WSS vector rather than from variation in the magnitude of the vectors. The pattern of transWSS was insensitive to inflow waveform; only unphysiologically high Womersley numbers produced substantial changes. However, transWSS was sensitive to changes in geometry. The curvature of the arch and proximal descending aorta were responsible for the principal features, the non-planar nature of the aorta produced asymmetries in the location and position of streaks of high transWSS, and taper determined the persistence of the streaks down the aorta. These results reflect the importance of the fluctuating strength of Dean vortices in generating transWSS. Copyright © 2016 Elsevier Ltd. All rights reserved.

Angular circulation speed of tablets in a vibratory tablet coating pan.

PubMed

Kumar, Rahul; Wassgren, Carl

2013-03-01

In this work, a single tablet model and a discrete element method (DEM) computer simulation are developed to obtain the angular circulation speed of tablets in a vibratory tablet coating pan for range of vibration frequencies and amplitudes. The models identify three important dimensionless parameters that influence the speed of the tablets: the dimensionless amplitude ratio (a/R), the Froude number (aω2/g), and the tablet-wall friction coefficient, where a is the peak vibration amplitude at the drum center, ω is the vibration angular frequency, R is the drum radius, and g is the acceleration due to gravity. The models predict that the angular circulation speed of tablets increases with an increase in each of these parameters. The rate of increase in the angular circulation speed is observed to decrease for larger values of a/R. The angular circulation speed reaches an asymptote beyond a tablet-wall friction coefficient value of about 0.4. Furthermore, it is found that the Froude number should be greater than one for the tablets to start circulating. The angular circulation speed increases as Froude number increases but then does not change significantly at larger values of the Froude number. Period doubling, where the motion of the bed is repeated every two cycles, occurs at a Froude number larger than five. The single tablet model, although much simpler than the DEM model, is able to predict the maximum circulation speed (the limiting case for a large value of tablet-wall friction coefficient) as well as the transition to period doubling.

The contributions of cardiac myosin binding protein C and troponin I phosphorylation to β‐adrenergic enhancement of in vivo cardiac function

PubMed Central

Gresham, Kenneth S.

2016-01-01

Key points β‐adrenergic stimulation increases cardiac myosin binding protein C (MyBP‐C) and troponin I phosphorylation to accelerate pressure development and relaxation in vivo, although their relative contributions remain unknown.Using a novel mouse model lacking protein kinase A‐phosphorylatable troponin I (TnI) and MyBP‐C, we examined in vivo haemodynamic function before and after infusion of the β‐agonist dobutamine.Mice expressing phospho‐ablated MyBP‐C displayed cardiac hypertrophy and prevented full acceleration of pressure development and relaxation in response to dobutamine, whereas expression of phosphor‐ablated TnI alone had little effect on the acceleration of contractile function in response to dobutamine.Our data demonstrate that MyBP‐C phosphorylation is the principal mediator of the contractile response to increased β‐agonist stimulation in vivo.These results help us understand why MyBP‐C dephosphorylation in the failing heart contributes to contractile dysfunction and decreased adrenergic reserve in response to acute stress. Abstract β‐adrenergic stimulation plays a critical role in accelerating ventricular contraction and speeding relaxation to match cardiac output to changing circulatory demands. Two key myofilaments proteins, troponin I (TnI) and myosin binding protein‐C (MyBP‐C), are phosphorylated following β‐adrenergic stimulation; however, their relative contributions to the enhancement of in vivo cardiac contractility are unknown. To examine the roles of TnI and MyBP‐C phosphorylation in β‐adrenergic‐mediated enhancement of cardiac function, transgenic (TG) mice expressing non‐phosphorylatable TnI protein kinase A (PKA) residues (i.e. serine to alanine substitution at Ser23/24; TnIPKA−) were bred with mice expressing non‐phosphorylatable MyBP‐C PKA residues (i.e. serine to alanine substitution at Ser273, Ser282 and Ser302; MyBPCPKA−) to generate a novel mouse model expressing non‐phosphorylatable PKA residues in TnI and MyBP‐C (DBLPKA−). MyBP‐C dephosphorylation produced cardiac hypertrophy and increased wall thickness in MyBPCPKA− and DBLPKA− mice, and in vivo echocardiography and pressure–volume catheterization studies revealed impaired systolic function and prolonged diastolic relaxation compared to wild‐type and TnIPKA– mice. Infusion of the β‐agonist dobutamine resulted in accelerated rates of pressure development and relaxation in all mice; however, MyBPCPKA− and DBLPKA− mice displayed a blunted contractile response compared to wild‐type and TnIPKA– mice. Furthermore, unanaesthesized MyBPCPKA− and DBLPKA− mice displayed depressed maximum systolic pressure in response to dobutamine as measured using implantable telemetry devices. Taken together, our data show that MyBP‐C phosphorylation is a critical modulator of the in vivo acceleration of pressure development and relaxation as a result of enhanced β‐adrenergic stimulation, and reduced MyBP‐C phosphorylation may underlie depressed adrenergic reserve in heart failure. PMID:26635197

Anomalous gravitropic response of Chara rhizoids during enhanced accelerations.

PubMed

Braun, M

1996-07-01

Centrifugal accelerations of 50-250 g were applied to rhizoids of Chara globularis Thuill. at stimulation angles (alpha) of 5-90 degrees between the acceleration vector and the rhizoid axis. After the start of centrifugation, the statoliths were pressed asymmetrically onto the centrifugal flank of the apical cell wall. In contrast to the well-known bending (by bowing) under 1 g, the rhizoids responded in two distinct phases. Following an initial phase of sharp bending (by bulging), which is similar to the negatively gravitropic response of Chara protonemata, rhizoids stopped bending and, in the second phase, grew straight in directions clearly deviating from the direction of acceleration. These response angles (beta) between the axis of the bent part of the rhizoid and the acceleration vector were strictly correlated with the g-level of acceleration. The higher the acceleration the greater was beta. Except for the sharp bending, the shape and growth rate of the centrifuged rhizoids were not different from those of gravistimulated control rhizoids at 1 g. These results indicate that gravitropic bending of rhizoids during enhanced accelerations (5 degrees < or = alpha < or = 90 degrees) is caused not only by subapical differential flank growth, as it is the case at 1 g, but also by also by the centripetal displacement of the growth centre as was recently discussed for the negative gravitropism of Chara protonemata. A hypothesis for cytoskeletally mediated polar growth is presented based on data from positive gravitropic bending of Chara rhizoids at 1 g and from the anomalous gravitropic bending of rhizoids compared with the negatively gravitropic bending of Chara protonemata. The data obtained are also relevant to a general understanding of graviperception in higher-plant organs.

MCNP6 unstructured mesh application to estimate the photoneutron distribution and induced activity inside a linac bunker

NASA Astrophysics Data System (ADS)

Juste, B.; Morató, S.; Miró, R.; Verdú, G.; Díez, S.

2017-08-01

Unwanted neutrons in radiation therapy treatments are typically generated by photonuclear reactions. High-energy beams emitted by medical Linear Accelerators (LinAcs) interact with high atomic number materials situated in the accelerator head and release neutrons. Since neutrons have a high relative biological effectiveness, even low neutron doses may imply significant exposure of patients. It is also important to study radioactivity induced by these photoneutrons when interacting with the different materials and components of the treatment head facility and the shielding room walls, since persons not present during irradiation (e.g. medical staff) may be exposed to them even when the accelerator is not operating. These problems are studied in this work in order to contribute to challenge the radiation protection in these treatment locations. The work has been performed by simulation using the latest state of the art of Monte-Carlo computer code MCNP6. To that, a detailed model of particles transport inside the bunker and treatment head has been carried out using a meshed geometry model. The LinAc studied is an Elekta Precise accelerator with a treatment photon energy of 15 MeV used at the Hospital Clinic Universitari de Valencia, Spain.

LIONs at the Stanford Linear Accelerator Center

DOE Office of Scientific and Technical Information (OSTI.GOV)

Constant, T.N.; Zdarko, R.W.; Simmons, R.H.

1998-01-01

The term LION is an acronym for Long Ionization Chamber. This is a distributed ion chamber which is used to monitor secondary ionization along the shield walls of a beam line resulting from incorrectly steered charged particle beams in lieu of the use of many discrete ion chambers. A cone of ionizing radiation emanating from a point source as a result of incorrect steering intercepts a portion of 1-5/8 inch Heliax cable (about 100 meters in length) filled with Argon gas at 20 psi and induces a pulsed current which is proportional to the ionizing charge. This signal is transmittedmore » via the cable to an integrator circuit whose output is directed to an electronic comparators, which in turn is used to turn off the accelerated primary beam when preset limits are exceeded. This device is used in the Stanford Linear Accelerator Center (SLAC) Beam Containment System (BCS) to prevent potentially hazardous ionizing radiation resulting from incorrectly steered beams in areas that might be occupied by people. This paper describes the design parameters and experience in use in the Final Focus Test Beam (FFTB) area of the Stanford Linear Accelerator Center.« less

External Beam Accelerated Partial Breast Irradiation Yields Favorable Outcomes in Patients with Prior Breast Augmentation

PubMed Central

Lei, Rachel Y.; Leonard, Charles E.; Howell, Kathryn T.; Henkenberns, Phyllis L.; Johnson, Timothy K.; Hobart, Tracy L.; Kercher, Jane M.; Widner, Jodi L.; Kaske, Terese; Barke, Lora D.; Carter, Dennis L.

2014-01-01

Purpose: To report outcomes in breast cancer patients with prior breast augmentation treated with external beam accelerated partial breast irradiation (EB-APBI) utilizing intensity-modulated radiotherapy or 3-dimensional conformal radiotherapy, both with IGRT. Materials and Methods: Sixteen stage 0/1 breast cancer patients with previous elective bilateral augmentation were treated post-lumpectomy on institutional EB-APBI trials (01185132 and 01185145 on clinicaltrials.gov). Patients received 38.5 Gy in 10 fractions over five consecutive days. Breast/chest wall pain and cosmesis were rated by patient; cosmesis was additionally evaluated by physician per RTOG criteria. Results: The median follow-up from accelerated partial breast irradiation (APBI) completion was 23.9 months (range, 1.2–58.6). Little to no change in cosmesis or pain from baseline was reported. Cosmetic outcomes at last follow-up were judged by patients as excellent/good in 81.2% (13/16), and by physicians as excellent/good in 93.8% (15/16). Ten patients (62.5%) reported no breast/chest wall pain, five (31.2%) reported mild pain, and one (6.2%) reported moderate pain. All patients remain disease free at last follow-up. The median ipsilateral breast, planning target volume (PTV), and implant volumes were 614, 57, and 333 cm3. The median ratios of PTV/ipsilateral breast volume (implant excluded) and PTV/total volume (implant included) were 9 and 6%. Conclusion: These 16 breast cancer cases with prior bilateral augmentation treated with EB-APBI demonstrate favorable clinical outcomes. Further exploration of EB-APBI as a treatment option for this patient population is warranted. PMID:24995159

Monte Carlo study of neutron-ambient dose equivalent to patient in treatment room.

PubMed

Mohammadi, A; Afarideh, H; Abbasi Davani, F; Ghergherehchi, M; Arbabi, A

2016-12-01

This paper presents an analytical method for the calculation of the neutron ambient dose equivalent H* (10) regarding patients, whereby the different concrete types that are used in the surrounding walls of the treatment room are considered. This work has been performed according to a detailed simulation of the Varian 2300C/D linear accelerator head that is operated at 18MV, and silver activation counter as a neutron detector, for which the Monte Carlo MCNPX 2.6 code is used, with and without the treatment room walls. The results show that, when compared to the neutrons that leak from the LINAC, both the scattered and thermal neutrons are the major factors that comprise the out-of field neutron dose. The scattering factors for the limonite-steel, magnetite-steel, and ordinary concretes have been calculated as 0.91±0.09, 1.08±0.10, and 0.371±0.01, respectively, while the corresponding thermal factors are 34.22±3.84, 23.44±1.62, and 52.28±1.99, respectively (both the scattering and thermal factors are for the isocenter region); moreover, the treatment room is composed of magnetite-steel and limonite-steel concretes, so the neutron doses to the patient are 1.79 times and 1.62 times greater than that from an ordinary concrete composition. The results also confirm that the scattering and thermal factors do not depend on the details of the chosen linear accelerator head model. It is anticipated that the results of the present work will be of great interest to the manufacturers of medical linear accelerators. Copyright © 2016. Published by Elsevier Ltd.

SSME main combustion chamber life prediction

NASA Technical Reports Server (NTRS)

Cook, R. T.; Fryk, E. E.; Newell, J. F.

1983-01-01

Typically, low cycle fatigue life is a function of the cyclic strain range, the material properties, and the operating temperature. The reusable life is normally defined by the number of strain cycles that can be accrued before severe material degradation occurs. Reusable life is normally signified by the initiation or propagation of surface cracks. Hot-fire testing of channel wall combustors has shown significant mid-channel wall thinning or deformation during accrued cyclic testing. This phenomenon is termed cyclic-creep and appears to be significantly accelerated at elevated surface temperatures. This failure mode was analytically modelled. The cyclic life of the baseline SSME-MCC based on measured calorimeter heat transfer data, and the life sensitivity of local hot spots caused by injector effects were determined. Four life enhanced designs were assessed.

Physics and material science of ultra-high quality factor superconducting resonator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vostrikov, Alexander

2015-08-01

The nitrogen doping into niobium superconducting radio frequency cavity walls aiming to improve the fundamental mode quality factor is the subject of the research in the given work. Quantitative nitrogen diffusion into niobium model calculating the concentration profile was developed. The model estimations were confirmed with secondary ion mass spectrometry technique measurements. The model made controlled nitrogen doping recipe optimization possible. As a result the robust reproducible recipe for SRF cavity walls treatment with nitrogen doping was developed. The cavities produced with optimized recipe met LCLS–II requirements on quality factor of 2.7 ∙ 10 10 at acceleration field of 16more » MV/m. The microscopic effects of nitrogen doping on superconducting niobium properties were studied with low energy muon spin rotation technique and magnetometer measurements. No significant effect of nitrogen on the following features was found: electron mean free path, magnetic field penetration depth, and upper and surface critical magnetic fields. It was detected that for nitrogen doped niobium samples magnetic flux starts to penetrate inside the superconductor at lower external magnetic field value compared to the low temperature baked niobium ones. This explains lower quench field of SRF cavities treated with nitrogen. Quality factor improvement of fundamental mode forced to analyze the high order mode (HOM) impact on the particle beam dynamics. Both resonant and cumulative effects caused by monopole and dipole HOMs respectively are found to be negligible within the requirements for LCLS–II.« less

Loss in photosynthesis during senescence is accompanied by an increase in the activity of β-galactosidase in leaves of Arabidopsis thaliana: modulation of the enzyme activity by water stress.

PubMed

Pandey, Jitendra Kumar; Dash, Sidhartha Kumar; Biswal, Basanti

2017-07-01

The precise nature of the developmental modulation of the activity of cell wall hydrolases that breakdown the wall polysaccharides to maintain cellular sugar homeostasis under sugar starvation environment still remains unclear. In this work, the activity of β-galactosidase (EC 3.2.1.23), a cell-wall-bound enzyme known to degrade the wall polysaccharides, has been demonstrated to remarkably enhance during senescence-induced loss in photosynthesis in Arabidopsis thaliana. The enhancement in the enzyme activity reaches a peak at the terminal phase of senescence when the rate of photosynthesis is at its minimum. Although the precise nature of chemistry of the interface between the decline in photosynthesis and enhancement in the activity of the enzyme could not be fully resolved, the enhancement in its activity in dark and its suppression in light or with exogenous sugars may indicate the involvement of loss of photosynthetic production of sugars as a key factor that initiates and stimulates the activity of the enzyme. The hydrolase possibly participates in the catabolic network of cell wall polysaccharides to produce sugars for execution of energy-dependant senescence program in the background of loss of photosynthesis. Drought stress experienced by the senescing leaves accelerates the decline in photosynthesis with further stimulation in the activity of the enzyme. The stress recovery of photosynthesis and suppression of the enzyme activity on withdrawal of stress support the proposition of photosynthetic modulation of the cell-wall-bound enzyme activity.

Implosion of Cylindrical Cavities via Short Duration Impulsive Loading

NASA Astrophysics Data System (ADS)

Huneault, Justin; Higgins, Andrew

2014-11-01

An apparatus has been developed to study the collapse of a cylindrical cavity in gelatin subjected to a symmetric impact-driven impulsive loading. A gas-driven annular projectile is accelerated to approximately 50 m/s, at which point it impacts a gelatin casting confined by curved steel surfaces that allow a transition from an annular geometry to a cylindrically imploding motion. The implosion is visualized by a high-speed camera through a window which forms the top confining wall of the implosion cavity. The initial size of the cavity is such that the gelatin wall is two to five times thicker than the impacting projectile. Thus, during impact the compression wave which travels towards the cavity is closely followed by a rarefaction resulting from the free surface reflection of the compression wave in the projectile. As the compression wave in the gelatin reaches the inner surface, it will also reflect as a rarefaction wave. The interaction between the rarefaction waves from the gelatin and projectile free surfaces leads to large tensile stresses resulting in the spallation of a relatively thin shell. The study focuses on the effect of impact parameters on the thickness and uniformity of the imploding shell formed by the cavitation in the imploding gelatin cylinder.

Preliminary study on detection technology of the cladding weld of spent fuel storage pool

NASA Astrophysics Data System (ADS)

Qi, Pan; Cui, Hongyan; Feng, Meiming; Shao, Wenbin; Liao, Shusheng; Li, Wei

2018-04-01

As the first barrier of the Spent fuel storage pool, the steel cladding using different sizes (length×width) of 304L stainless steel with 3˜6mm thickness plate argon arc welded together which is direct contacted with boric acid water. Environmental humidity between the back of steel cladding and concrete, makes phosphate, chloride ion overflowed from the concrete that corroded on the weld zone with different mechanism. Part of the corrosion defects can penetrate leaded to leakage of boric acid water in penetration position accelerated crack propagation. In view of the above situation and combined with the actual needs of the power plant, the development of effective underwater nondestructive testing means of the weld area for periodic inspection and monitoring is necessary. A single method may lead to the missing of defects detection due to weld reinforcement unpolished. In this paper, eddy current array (ARRAY) and Alternating Current Field Measurement (ACFM) are adapted to test the limit sensitivity and resolution through by the specimens with artificial defects which make their detection abilities close to satisfy engineering requirements. The preliminary study found that Φ0.5mm through-wall hole and with 2mm length and 0.3mm width through-wall crack in the weld can be good inspected.

Study of the Formation Mechanism of A-Segregation Based on Microstructural Morphology

NASA Astrophysics Data System (ADS)

Zhang, Zhao; Bao, Yuchong; Liu, Lin; Pian, Song; Li, Ri

2018-04-01

A model that combines a cellular automaton (CA) and lattice Boltzmann method (LBM) is presented. The mechanism of A-segregation in an Fe-0.34 wt pct C alloy ingot is analyzed on the basis of microstructural morphology calculations. The CA is used to capture the solid/liquid interface, while the LBM is used to calculate the transport phenomena. (1) The solidification of global columnar dendrites was simulated, and two obvious A-segregation bands appeared in the middle-radius region between the ingot wall surface and the centerline. In addition, the angle of deflection to the centerline increased with the increasing heat dissipation rate of the wall surface. When natural convection was ignored, the A-segregation disappeared, and only positive segregation was present in the center and bottom corner of the ingot. (2) Mixed columnar-equiaxed solidification was simulated. Many A-segregation bands appeared in the ingot. (3) Global equiaxed solidification was simulated, and no A-segregation bands were found. The results show that the upward movement of the high-concentration melt is the key to the formation of A-segregation bands, and remelting and the emergence of equiaxed grains are not necessary conditions to develop these bands. However, the appearance of equiaxed grains accelerates the formation of vortexes; thus, many A-segregation bands appear during columnar-equiaxed solidification.

Solvent Extraction of Chemical Attribution Signature Compounds from Painted Wall Board: Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wahl, Jon H.; Colburn, Heather A.

2009-10-29

This report summarizes work that developed a robust solvent extraction procedure for recovery of chemical attribution signature (CAS) compound dimethyl methyl phosphonate (DMMP) (as well as diethyl methyl phosphonate (DEMP), diethyl methyl phosphonothioate (DEMPT), and diisopropyl methyl phosphonate (DIMP)) from painted wall board (PWB), which was selected previously as the exposed media by the chemical attribution scientific working group (CASWG). An accelerated solvent extraction approach was examined to determine the most effective method of extraction from PWB. Three different solvent systems were examined, which varied in solvent strength and polarity (i.e., 1:1 dichloromethane : acetone,100% methanol, and 1% isopropanol inmore » pentane) with a 1:1 methylene chloride : acetone mixture having the most robust and consistent extraction for four original target organophosphorus compounds. The optimum extraction solvent was determined based on the extraction efficiency of the target analytes from spiked painted wallboard as determined by gas chromatography x gas chromatography mass spectrometry (GCxGC-MS) analysis of the extract. An average extraction efficiency of approximately 60% was obtained for these four compounds. The extraction approach was further demonstrated by extracting and detecting the chemical impurities present in neat DMMP that was vapor-deposited onto painted wallboard tickets.« less

High Reynolds number turbulence model of rotating shear flows

NASA Astrophysics Data System (ADS)

Masuda, S.; Ariga, I.; Koyama, H. S.

1983-09-01

A Reynolds stress closure model for rotating turbulent shear flows is developed. Special attention is paid to keeping the model constants independent of rotation. First, general forms of the model of a Reynolds stress equation and a dissipation rate equation are derived, the only restrictions of which are high Reynolds number and incompressibility. The model equations are then applied to two-dimensional equilibrium boundary layers and the effects of Coriolis acceleration on turbulence structures are discussed. Comparisons with the experimental data and with previous results in other external force fields show that there exists a very close analogy between centrifugal, buoyancy and Coriolis force fields. Finally, the model is applied to predict the two-dimensional boundary layers on rotating plane walls. Comparisons with existing data confirmed its capability of predicting mean and turbulent quantities without employing any empirical relations in rotating fields.

Electrophoresis technology

NASA Technical Reports Server (NTRS)

Snyder, R. S.

1985-01-01

A new high resolution apparatus designed for space was built as a laboratory prototype. Using a moving wall with a low zeta potential coating, the major sources of flow distortion for an electrophoretic sample stream are removed. Highly resolved fractions, however, will only be produced in space because of the sensitivity of this chamber to buoyancy-induced convection in the laboratory. The second and third flights of the McDonnell Douglas Astronautics Corporation continuous flow electrophoresis system carried samples developed at MSFC intended to evaluate the broad capabilities of free flow electrophoresis in a reduced gravity environment. Biological model materials, hemoglobin and polystyrene latex microspheres, were selected because of their past use as electrophoresis standards and as visible markers for fluid flow due to electroosmosis, spacecraft acceleration or other factors. The dependence of the separation resolution on the properties of the sample and its suspension solution was assessed.

Comparative Biomechanical Behavior and Healing Profile of a Novel Thinned Wall Ultrahigh Molecular Weight Amorphous Poly-l-Lactic Acid Sirolimus-Eluting Bioresorbable Coronary Scaffold.

PubMed

Cheng, Yanping; Gasior, Pawel; Xia, Jing-Gang; Ramzipoor, Kamal; Lee, Chang; Estrada, Edward A; Dokko, Daniell; McGregor, Jenn C; Conditt, Gerard B; McAndrew, Thomas; Kaluza, Greg L; Granada, Juan F

2017-07-01

Mechanical strength of bioresorbable scaffolds (BRS) is highly dependent on strut dimensions and polymer features. To date, the successful development of thin-walled BRS has been challenging. We compared the biomechanical behavior and vascular healing profile of a novel thin-walled (115 µm) sirolimus-eluting ultrahigh molecular weight amorphous poly-l-lactic acid-based BRS (APTITUDE, Amaranth Medical [AMA]) to Absorb (bioresorbable vascular scaffold [BVS]) using different experimental models. In vitro biomechanical testing showed no fractures in the AMA-BRS when overexpanded 1.3 mm above nominal dilatation values (≈48%) and lower number of fractures on accelerated cycle testing over time (at 21 K cycles=20.0 [19.5-20.5] in BVS versus 4.0 [3.0-4.3] in AMA-BRS). In the healing response study, 35 AMA-BRS and 23 BVS were implanted in 58 coronary arteries of 23 swine and followed-up to 180 days. Scaffold strut healing was evaluated in vivo using weekly optical coherence tomography analysis. At 14 days, the AMA-BRS demonstrated a higher percentage of embedded struts (71.0% [47.6, 89.1] compared with BVS 40.3% [20.5, 63.2]; P =0.01). At 21 days, uncovered struts were still present in the BVS group (3.8% [2.1, 10.2]). Histopathology revealed lower area stenosis (AMA-BRS, 21.0±6.1% versus BVS 31.0±4.5%; P =0.002) in the AMA-BRS at 28 days. Neointimal thickness and inflammatory scores were comparable between both devices at 180 days. A new generation thinned wall BRS displayed a more favorable biomechanical behavior and strut healing profile compared with BVS in normal porcine coronary arteries. This novel BRS concept has the potential to improve the clinical outcomes of current generation BRS. © 2017 American Heart Association, Inc.

Cell Wall Composition and Candidate Biosynthesis Gene Expression During Rice Development.

PubMed

Lin, Fan; Manisseri, Chithra; Fagerström, Alexandra; Peck, Matthew L; Vega-Sánchez, Miguel E; Williams, Brian; Chiniquy, Dawn M; Saha, Prasenjit; Pattathil, Sivakumar; Conlin, Brian; Zhu, Lan; Hahn, Michael G; Willats, William G T; Scheller, Henrik V; Ronald, Pamela C; Bartley, Laura E

2016-10-01

Cell walls of grasses, including cereal crops and biofuel grasses, comprise the majority of plant biomass and intimately influence plant growth, development and physiology. However, the functions of many cell wall synthesis genes, and the relationships among and the functions of cell wall components remain obscure. To better understand the patterns of cell wall accumulation and identify genes that act in grass cell wall biosynthesis, we characterized 30 samples from aerial organs of rice (Oryza sativa cv. Kitaake) at 10 developmental time points, 3-100 d post-germination. Within these samples, we measured 15 cell wall chemical components, enzymatic digestibility and 18 cell wall polysaccharide epitopes/ligands. We also used quantitative reverse transcription-PCR to measure expression of 50 glycosyltransferases, 15 acyltransferases and eight phenylpropanoid genes, many of which had previously been identified as being highly expressed in rice. Most cell wall components vary significantly during development, and correlations among them support current understanding of cell walls. We identified 92 significant correlations between cell wall components and gene expression and establish nine strong hypotheses for genes that synthesize xylans, mixed linkage glucan and pectin components. This work provides an extensive analysis of cell wall composition throughout rice development, identifies genes likely to synthesize grass cell walls, and provides a framework for development of genetically improved grasses for use in lignocellulosic biofuel production and agriculture. © The Author 2016. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Study of the Reynolds Number Effect on the Process of Instability Transition Into the Turbulent Stage.

PubMed

Nevmerzhitskiy, N V; Sotskov, E A; Sen'kovskiy, E D; Krivonos, O L; Polovnikov, A A; Levkina, E V; Frolov, S V; Abakumov, S A; Marmyshev, V V

2014-09-01

The results of the experimental study of the Reynolds number effect on the process of the Rayleigh-Taylor (R-T) instability transition into the turbulent stage are presented. The experimental liquid layer was accelerated by compressed gas. Solid particles were scattered on the layer free surface to specify the initial perturbations in some experiments. The process was recorded with the use of a high-speed motion picture camera. The following results were obtained in experiments: (1) Long-wave perturbation is developed at the interface at the Reynolds numbers Re < 10 4 . If such perturbation growth is limited by a hard wall, the jet directed in gas is developed. If there is no such limitation, this perturbation is resolved into the short-wave ones with time, and their growth results in gas-liquid mixing. (2) Short-wave perturbations specified at the interface significantly reduce the Reynolds number Re for instability to pass into the turbulent mixing stage.

Pathogenesis of Arrhythmogenic Cardiomyopathy

PubMed Central

Asimaki, Angeliki; Kleber, Andre G.; Saffitz, Jeffrey E.

2015-01-01

Arrhythmogenic cardiomyopathy (ACM) is a primary myocardial disease. It is characterized by frequent ventricular arrhythmias and increased risk of sudden cardiac death typically arising as an early manifestation before the onset of significant myocardial remodeling. Myocardial degeneration, often confined to the right ventricular free wall, with replacement by fibrofatty scar tissue, develops in many patients. ACM is a familial disease but genetic penetrance can be low and disease expression is highly variable. Inflammation may promote disease progression. It also appears that exercise increases disease penetrance and accelerates its development. More than 60% of probands harbor mutations in genes encoding desmosomal proteins, which has raised the possibility that defective cell-cell adhesion may play a role in disease pathogenesis. Recent advances have implicated changes in the canonical Wnt/β-catenin and Hippo signaling pathways and defects in forwarding trafficking of ion channels and other proteins to the intercalated disk in cardiac myocytes. This review summarizes current understanding of the pathogenesis of ACM and highlights future research directions. PMID:26199027

SU-F-E-18: Training Monthly QA of Medical Accelerators: Illustrated Instructions for Self-Learning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Court, L; Wang, H; Aten, D

Purpose: To develop and test clear illustrated instructions for training of monthly mechanical QA of medical linear accelerators. Methods: Illustrated instructions were created for monthly mechanical QA with tolerance tabulated, and underwent several steps of review and refinement. Testers with zero QA experience were then recruited from our radiotherapy department (1 student, 2 computational scientists and 8 dosimetrists). The following parameters were progressively de-calibrated on a Varian C-series linac: Group A = gantry angle, ceiling laser position, X1 jaw position, couch longitudinal position, physical graticule position (5 testers); Group B = Group A + wall laser position, couch lateral andmore » vertical position, collimator angle (3 testers); Group C = Group B + couch angle, wall laser angle, and optical distance indicator (3 testers). Testers were taught how to use the linac, and then used the instructions to try to identify these errors. A physicist observed each session, giving support on machine operation, as necessary. The instructions were further tested with groups of therapists, graduate students and physics residents at multiple institutions. We have also changed the language of the instructions to simulate using the instructions with non-English speakers. Results: Testers were able to follow the instructions. They determined gantry, collimator and couch angle errors within 0.4, 0.3, and 0.9degrees of the actual changed values, respectively. Laser positions were determined within 1mm, and jaw positions within 2mm. Couch position errors were determined within 2 and 3mm for lateral/longitudinal and vertical errors, respectively. Accessory positioning errors were determined within 1mm. ODI errors were determined within 2mm when comparing with distance sticks, and 6mm when using blocks, indicating that distance sticks should be the preferred approach for inexperienced staff. Conclusion: Inexperienced users were able to follow these instructions, and catch errors within the criteria suggested by AAPM TG142 for linacs used for IMRT.« less

Dosimetric feasibility of using tungsten-based functional paper for flexible chest wall protectors in intraoperative electron radiotherapy for breast cancer

NASA Astrophysics Data System (ADS)

Kamomae, Takeshi; Monzen, Hajime; Kawamura, Mariko; Okudaira, Kuniyasu; Nakaya, Takayoshi; Mukoyama, Takashi; Miyake, Yoshikazu; Ishihara, Yoshitomo; Itoh, Yoshiyuki; Naganawa, Shinji

2018-01-01

Intraoperative electron radiotherapy (IOERT), which is an accelerated partial breast irradiation method, has been used for early-stage breast cancer treatment. In IOERT, a protective disk is inserted behind the target volume to minimize the dose received by normal tissues. However, to use such a disk, the surgical incision must be larger than the field size because the disk is manufactured from stiff and unyielding materials. In this study, the applicability of newly developed tungsten-based functional paper (TFP) was assessed as an alternative to the existing protective disk. The radiation-shielding performance of the TFP was verified through experimental measurements and Monte Carlo simulations. Percentage depth dose curves and lateral dose profiles with and without TFPs were measured and simulated on a dedicated IOERT accelerator. The number of piled-up TFPs was changed from 1 to 40. In the experimental measurements, the relative doses at the exit plane of the TFPs for 9 MeV were 42.7%, 9.2%, 0.2%, and 0.1% with 10, 20, 30, and 40 TFPs, respectively, whereas those for 12 MeV were 63.6%, 27.1%, 8.6%, and 0.2% with 10, 20, 30, and 40 TFPs, respectively. Slight dose enhancements caused by backscatter radiation from the TFPs were observed at the entrance plane of the TFPs at both beam energies. The results of the Monte Carlo simulation indicated the same tendency as the experimental measurements. Based on the experimental and simulated results, the radiation-shielding performances of 30 TFPs for 9 MeV and 40 TFPs for 12 MeV were confirmed to be acceptable and close to those of the existing protective disk. The findings of this study suggest the feasibility of using TFPs as flexible chest wall protectors in IOERT for breast cancer treatment.

Transient Simulation of Ram Accelerator Flowfields

DTIC Science & Technology

1993-01-01

PROPULSIVE FLOWS WITH COMIBUSTION CHEMISTRY, ADVANCED TURBULENCE MODELS - 1񕚑ŕ. Reference: Dash, "Advanced Computational Models for Analyzing High - Speed...coupled, implicit manner. Near-wall effects have been dealt with via the low Reynolds number formulation of Chien: and the recent model of Rodi.3 High ...July 1989. 19 Dash, S.M., ’Advanced Computational Models for Analyzing High -Speed Propulsive Flowficlds,’ 199M J&ý,NAF Propulsion Meeting, CPIA Pub. 550

Growth and characterization of AgGa0.5In0.5Se2 single crystals by modified vertical Bridgman method

NASA Astrophysics Data System (ADS)

Vijayakumar, P.; Ramasamy, P.

2016-05-01

AgGa0.5In0.5Se2 single crystal was grown using a double wall quartz ampoule with accelerated crucible rotation technique by modified vertical Bridgman method. The structural perfection was measured using HRXRD. The grown single crystal composition was measured using ICP-OES analysis and compositional uniformities were measured using Raman spectroscopy analysis. Photoconductivity measurements confirm the positive photoconducting nature.

Summer Research Program (1992). Summer Faculty Research Program (SFRP) Reports. Volume 2. Armstrong Laboratory

DTIC Science & Technology

1992-12-01

desirable. In this study, the proposed model consists of a thick-walled, highly deformable elastic tube in which the blood flow is described by linearized ...presented a mechanical model consisting of linearized Navier-Stokes and finite elasticity equations to predict blood pooling under acceleration stress... linear multielement model of the cardiovascular system which can calculate blood pressures and flows at any point in the cardio- vascular system. It

Explosively separable casing

DOEpatents

Jacobson, A.K.; Rychnovsky, R.E.; Visbeck, C.N.

An explosively separable casing including a cylindrical afterbody and a circular cover for one end of the afterbody is disclosed. The afterbody has a cylindrical tongue extending longitudinally from one end which is matingly received in a corresponding groove in the cover. The groove is sized to provide a picket between the end of the tongue and the remainder of the groove so that an explosive can be located therein. A seal is also provided between the tongue and the groove for sealing the pocket from the atmosphere. A frangible holding device is utilized to hold the cover to the afterbody. When the explosive is ignited, the increase in pressure in the pocket causes the cover to be accelerated away from the afterbody. Preferably, the inner wall of the afterbody is in the same plane as the inner wall of the tongue to provide a maximum space for storage in the afterbody and the side wall of the cover is thicker than the side wall of the afterbody so as to provide a sufficiently strong surrounding portion for the pocket in which the explosion takes place. The detonator for the explosive is also located on the cover and is carried away with the cover during separation. The seal is preferably located at the longitudinal end of the tongue and has a chevron cross section.

Explosively separable casing

DOEpatents

Jacobson, Albin K.; Rychnovsky, Raymond E.; Visbeck, Cornelius N.

1985-01-01

An explosively separable casing including a cylindrical afterbody and a circular cover for one end of the afterbody is disclosed. The afterbody has a cylindrical tongue extending longitudinally from one end which is matingly received in a corresponding groove in the cover. The groove is sized to provide a pocket between the end of the tongue and the remainder of the groove so that an explosive can be located therein. A seal is also provided between the tongue and the groove for sealing the pocket from the atmosphere. A frangible holding device is utilized to hold the cover to the afterbody. When the explosive is ignited, the increase in pressure in the pocket causes the cover to be accelerated away from the afterbody. Preferably, the inner wall of the afterbody is in the same plane as the inner wall of the tongue to provide a maximum space for storage in the afterbody and the side wall of the cover is thicker than the side wall of the afterbody so as to provide a sufficiently strong surrounding portion for the pocket in which the explosion takes place. The detonator for the explosive is also located on the cover and is carried away with the cover during separation. The seal is preferably located at the longitudinal end of the tongue and has a chevron cross section.

CFD Application to Flow-Accelerated Corrosion in Feeder Bends

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pietralik, John M.; Smith, Bruce A.W.

2006-07-01

Feeder piping in CANDU{sup R} plants experiences a thinning degradation mechanism called Flow-Accelerated Corrosion (FAC). The piping is made of carbon steel and has high water flow speeds. Although the water chemistry is highly alkaline with room-temperature pH in a range of 10.0-10.5, the piping has FAC rates exceeding 0.1 mm/year in some locations, e.g., in bends. One of the most important parameters affecting the FAC rate is the mass transfer coefficient for convective mass transport of ferrous ions. The ions are created at the pipe wall as a result of corrosion, diffuse through the oxide layer, and are transportedmore » from the oxide-layer/water interface to the bulk water by mass transport. Consequently, the local flow characteristics contribute to the highly turbulent convective mass transfer. Plant data and laboratory experiments indicate that the mass transfer step dominates FAC under feeder conditions. In this study, the flow and mass transfer in a feeder bend under operating conditions were simulated using the Fluent{sup TM} computer code. Because the flow speed is very high, with the Reynolds numbers in a range of several millions, and because the geometry is complex, experiments in a 1:1 scale were conducted with the main objective to validate flow simulations. The experiments measured pressure at several key locations and visualized the flow. The flow and mass transfer models were validated using available friction-factor and mass transfer correlations and literature experiments on mass transfer in a bend. The validation showed that the turbulence model that best predicts the experiments is the realizable k-{epsilon} model. Other two-equation turbulence models, as well as one-equation models and Reynolds stress models were tried. The near-wall treatment used the non-equilibrium wall functions. The wall functions were modified for surface roughness when necessary. A comparison of the local mass transfer coefficient with measured FAC rate in plant specimens shows very good agreement. Visualization experiments indicate secondary flows in the bends. No boundary layer separation was observed in experiments or in simulations. (authors)« less

Fluid mechanical consequences of pendular activity, segmentation and pyloric outflow in the proximal duodenum of the rat and the guinea pig

PubMed Central

de Loubens, Clément; Lentle, Roger G.; Love, Richard J.; Hulls, Corrin; Janssen, Patrick W. M.

2013-01-01

We conducted numerical experiments to study the influence of non-propagating longitudinal and circular contractions, i.e. pendular activity and segmentation, respectively, on flow and mixing in the proximal duodenum. A lattice-Boltzmann numerical method was developed to simulate the fluid mechanical consequences for each of 22 randomly selected sequences of high-definition video of real longitudinal and radial contractile activity in the isolated proximal duodenum of the rat and guinea pig. During pendular activity in the rat duodenum, the flow was characterized by regions of high shear rate. Mixing was so governed by shearing deformation of the fluid that increased the interface between adjacent domains and accelerated their inter-diffusion (for diffusion coefficients approx. less than 10−8 m² s−1). When pendular activity was associated with a slow gastric outflow characteristic of post-prandial period, the dispersion was also improved, especially near the walls. Mixing was not promoted by isolated segmentative contractions in the guinea pig duodenum and not notably influenced by pylorus outflow. We concluded that pendular activity generates mixing of viscous fluids ‘in situ’ and accelerates the diffusive mass transfer, whereas segmentation may be more important in mixing particulate suspensions with high solid volume ratios. PMID:23536539

Fluid mechanical consequences of pendular activity, segmentation and pyloric outflow in the proximal duodenum of the rat and the guinea pig.

PubMed

de Loubens, Clément; Lentle, Roger G; Love, Richard J; Hulls, Corrin; Janssen, Patrick W M

2013-06-06

We conducted numerical experiments to study the influence of non-propagating longitudinal and circular contractions, i.e. pendular activity and segmentation, respectively, on flow and mixing in the proximal duodenum. A lattice-Boltzmann numerical method was developed to simulate the fluid mechanical consequences for each of 22 randomly selected sequences of high-definition video of real longitudinal and radial contractile activity in the isolated proximal duodenum of the rat and guinea pig. During pendular activity in the rat duodenum, the flow was characterized by regions of high shear rate. Mixing was so governed by shearing deformation of the fluid that increased the interface between adjacent domains and accelerated their inter-diffusion (for diffusion coefficients approx. less than 10(-8) m² s(-1)). When pendular activity was associated with a slow gastric outflow characteristic of post-prandial period, the dispersion was also improved, especially near the walls. Mixing was not promoted by isolated segmentative contractions in the guinea pig duodenum and not notably influenced by pylorus outflow. We concluded that pendular activity generates mixing of viscous fluids 'in situ' and accelerates the diffusive mass transfer, whereas segmentation may be more important in mixing particulate suspensions with high solid volume ratios.

Enhancing RHIC luminosity capabilities with in-situ beam piple coating

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herschcovitch,A.; Blaskiewicz, M.; Fischer, W.

Electron clouds have been observed in many accelerators, including the Relativistic Heavy Ion Collider (RHIC) at the Brookhaven National Laboratory (BNL). They can limit the machine performance through pressure degradation, beam instabilities or incoherent emittance growth. The formation of electron clouds can be suppressed with beam pipe surfaces that have low secondary electron yield. At the same time, high wall resistivity in accelerators can result in levels of ohmic heating unacceptably high for superconducting magnets. This is a concern for the RHIC machine, as its vacuum chamber in the superconducting dipoles is made from relatively high resistivity 316LN stainless steel.more » The high resistivity can be addressed with a copper (Cu) coating; a reduction in the secondary electron yield can be achieved with a titanium nitride (TiN) or amorphous carbon (a-C) coating. Applying such coatings in an already constructed machine is rather challenging. We started developing a robotic plasma deposition technique for in-situ coating of long, small diameter tubes. The technique entails fabricating a device comprised of staged magnetrons and/or cathodic arcs mounted on a mobile mole for deposition of about 5 {micro}m (a few skin depths) of Cu followed by about 0.1 {micro}m of TiN (or a-C).« less

Vorticity dynamics in an intracranial aneurysm

NASA Astrophysics Data System (ADS)

Le, Trung; Borazjani, Iman; Sotiropoulos, Fotis

2008-11-01

Direct Numerical Simulation is carried out to investigate the vortex dynamics of physiologic pulsatile flow in an intracranial aneurysm. The numerical solver is based on the CURVIB (curvilinear grid/immersed boundary method) approach developed by Ge and Sotiropoulos, J. Comp. Physics, 225 (2007) and is applied to simulate the blood flow in a grid with 8 million grid nodes. The aneurysm geometry is extracted from MRI images from common carotid artery (CCA) of a rabbit (courtesy Dr.Kallmes, Mayo Clinic). The simulation reveals the formation of a strong vortex ring at the proximal end during accelerated flow phase. The vortical structure advances toward the aneurysm dome forming a distinct inclined circular ring that connects with the proximal wall via two long streamwise vortical structures. During the reverse flow phase, the back flow results to the formation of another ring at the distal end that advances in the opposite direction toward the proximal end and interacts with the vortical structures that were created during the accelerated phase. The basic vortex formation mechanism is similar to that observed by Webster and Longmire (1998) for pulsed flow through inclined nozzles. The similarities between the two flows will be discussed and the vorticity dynamics of an aneurysm and inclined nozzle flows will be analyzed.This work was supported in part by the University of Minnesota Supercomputing Institute.

Accelerating Gas Adsorption on 3D Percolating Carbon Nanotubes.

PubMed

Li, Hui; Wen, Chenyu; Zhang, Youwei; Wu, Dongping; Zhang, Shi-Li; Qiu, Zhi-Jun

2016-02-18

In the field of electronic gas sensing, low-dimensional semiconductors such as single-walled carbon nanotubes (SWCNTs) can offer high detection sensitivity owing to their unprecedentedly large surface-to-volume ratio. The sensitivity and responsivity can further improve by increasing their areal density. Here, an accelerated gas adsorption is demonstrated by exploiting volumetric effects via dispersion of SWCNTs into a percolating three-dimensional (3D) network in a semiconducting polymer. The resultant semiconducting composite film is evaluated as a sensing membrane in field effect transistor (FET) sensors. In order to attain reproducible characteristics of the FET sensors, a pulsed-gate-bias measurement technique is adopted to eliminate current hysteresis and drift of sensing baseline. The rate of gas adsorption follows the Langmuir-type isotherm as a function of gas concentration and scales with film thickness. This rate is up to 5 times higher in the composite than only with an SWCNT network in the transistor channel, which in turn results in a 7-fold shorter time constant of adsorption with the composite. The description of gas adsorption developed in the present work is generic for all semiconductors and the demonstrated composite with 3D percolating SWCNTs dispersed in functional polymer represents a promising new type of material for advanced gas sensors.

Bioactivity and electrochemical behavior of hydroxyapatite-silicon-multi walled carbon nano-tubes composite coatings synthesized by EPD on NiTi alloys in simulated body fluid.

PubMed

Khalili, V; Khalil-Allafi, J; Frenzel, J; Eggeler, G

2017-02-01

In order to improve the surface bioactivity of NiTi bone implant and corrosion resistance, hydroxyapatite coating with addition of 20wt% silicon, 1wt% multi walled carbon nano-tubes and both of them were deposited on a NiTi substrate using a cathodic electrophoretic method. The apatite formation ability was estimated using immersion test in the simulated body fluid for 10days. The SEM images of the surface of coatings after immersion in simulated body fluid show that the presence of silicon in the hydroxyapatite coatings accelerates in vitro growth of apatite layer on the coatings. The Open-circuit potential and electrochemical impedance spectroscopy were measured to evaluate the electrochemical behavior of the coatings in the simulated body fluid at 37°C. The results indicate that the compact structure of hydroxyapatite-20wt% silicon and hydroxyapatite-20wt% silicon-1wt% multi walled carbon nano-tubes coatings could efficiently increase the corrosion resistance of NiTi substrate. Copyright © 2016 Elsevier B.V. All rights reserved.

The beetle elytron plate: a lightweight, high-strength and buffering functional-structural bionic material.

PubMed

Zhang, Xiaoming; Xie, Juan; Chen, Jinxiang; Okabe, Yoji; Pan, Longcheng; Xu, Mengye

2017-06-30

To investigate the characteristics of compression, buffering and energy dissipation in beetle elytron plates (BEPs), compression experiments were performed on BEPs and honeycomb plates (HPs) with the same wall thickness in different core structures and using different molding methods. The results are as follows: 1) The compressive strength and energy dissipation capacity in the BEP are 2.44 and 5.0 times those in the HP, respectively, when the plates are prepared using the full integrated method (FIM). 2) The buckling stress is directly proportional to the square of the wall thickness (t). Thus, for core structures with equal wall thicknesses, although the core volume of the BEP is 42 percent greater than that of the HP, the mechanical properties of the BEP are several times higher than those of the HP. 3) It is also proven that even when the single integrated method (SIM) is used to prepare BEPs, the properties discussed above remain superior to those of HPs by a factor of several; this finding lays the foundation for accelerating the commercialization of BEPs based on modern manufacturing processes.

Seismic Vulnerability and Performance Level of confined brick walls

NASA Astrophysics Data System (ADS)

Ghalehnovi, M.; Rahdar, H. A.

2008-07-01

There has been an increase on the interest of Engineers and designers to use designing methods based on displacement and behavior (designing based on performance) Regarding to the importance of resisting structure design against dynamic loads such as earthquake, and inability to design according to prediction of nonlinear behavior element caused by nonlinear properties of constructional material. Economically speaking, easy carrying out and accessibility of masonry material have caused an enormous increase in masonry structures in villages, towns and cities. On the other hand, there is a necessity to study behavior and Seismic Vulnerability in these kinds of structures since Iran is located on the earthquake belt of Alpide. Different reasons such as environmental, economic, social, cultural and accessible constructional material have caused different kinds of constructional structures. In this study, some tied walls have been modeled with software and with relevant accelerator suitable with geology conditions under dynamic analysis to research on the Seismic Vulnerability and performance level of confined brick walls. Results from this analysis seem to be satisfactory after comparison of them with the values in Code ATC40, FEMA and standard 2800 of Iran.

Role of turgor pressure in endocytosis in fission yeast

PubMed Central

Basu, Roshni; Munteanu, Emilia Laura; Chang, Fred

2014-01-01

Yeast and other walled cells possess high internal turgor pressure that allows them to grow and survive in the environment. This turgor pressure, however, may oppose the invagination of the plasma membrane needed for endocytosis. Here we study the effects of turgor pressure on endocytosis in the fission yeast Schizosaccharomyces pombe by time-lapse imaging of individual endocytic sites. Decreasing effective turgor pressure by addition of sorbitol to the media significantly accelerates early steps in the endocytic process before actin assembly and membrane ingression but does not affect the velocity or depth of ingression of the endocytic pit in wild-type cells. Sorbitol also rescues endocytic ingression defects of certain endocytic mutants and of cells treated with a low dose of the actin inhibitor latrunculin A. Endocytosis proceeds after removal of the cell wall, suggesting that the cell wall does not contribute mechanically to this process. These studies suggest that endocytosis is governed by a mechanical balance between local actin-dependent inward forces and opposing forces from high internal turgor pressure on the plasma membrane. PMID:24403609

Kinetic particle simulation of discharge and wall erosion of a Hall thruster

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cho, Shinatora; Komurasaki, Kimiya; Arakawa, Yoshihiro

2013-06-15

The primary lifetime limiting factor of Hall thrusters is the wall erosion caused by the ion induced sputtering, which is predominated by dielectric wall sheath and pre-sheath. However, so far only fluid or hybrid simulation models were applied to wall erosion and lifetime studies in which this non-quasi-neutral and non-equilibrium area cannot be treated directly. Thus, in this study, a 2D fully kinetic particle-in-cell model was presented for Hall thruster discharge and lifetime simulation. Because the fully kinetic lifetime simulation was yet to be achieved so far due to the high computational cost, the semi-implicit field solver and the techniquemore » of mass ratio manipulation was employed to accelerate the computation. However, other artificial manipulations like permittivity or geometry scaling were not used in order to avoid unrecoverable change of physics. Additionally, a new physics recovering model for the mass ratio was presented for better preservation of electron mobility at the weakly magnetically confined plasma region. The validity of the presented model was examined by various parametric studies, and the thrust performance and wall erosion rate of a laboratory model magnetic layer type Hall thruster was modeled for different operation conditions. The simulation results successfully reproduced the measurement results with typically less than 10% discrepancy without tuning any numerical parameters. It is also shown that the computational cost was reduced to the level that the Hall thruster fully kinetic lifetime simulation is feasible.« less

International strategy for fusion materials development

NASA Astrophysics Data System (ADS)

Ehrlich, Karl; Bloom, E. E.; Kondo, T.

2000-12-01

In this paper, the results of an IEA-Workshop on Strategy and Planning of Fusion Materials Research and Development (R&D), held in October 1998 in Risø Denmark are summarised and further developed. Essential performance targets for materials to be used in first wall/breeding blanket components have been defined for the major materials groups under discussion: ferritic-martensitic steels, vanadium alloys and ceramic composites of the SiC/SiC-type. R&D strategies are proposed for their further development and qualification as reactor-relevant materials. The important role of existing irradiation facilities (mainly fission reactors) for materials testing within the next decade is described, and the limits for the transfer of results from such simulation experiments to fusion-relevant conditions are addressed. The importance of a fusion-relevant high-intensity neutron source for the development of structural as well as breeding and special purpose materials is elaborated and the reasons for the selection of an accelerator-driven D-Li-neutron source - the International Fusion Materials Irradiation Facility (IFMIF) - as an appropriate test bed are explained. Finally the necessity to execute the materials programme for fusion in close international collaboration, presently promoted by the International Energy Agency, IEA is emphasised.

Re-Shielding of Cobalt-60 Teletherapy Rooms for Tomotherapy and Conventional Linear Accelerators using Monte Carlo Simulations

NASA Astrophysics Data System (ADS)

Çeçen, Yiğit; Yazgan, Çağrı

2017-09-01

Purpose. Nearly all Cobalt-60 teletherapy machines were removed around the world during the last two decades. The remaining ones are being used for experimental purposes. However, the rooms of these teletherapy machines are valuable because of lack of space in radiotherapy clinics. In order to place a new technology treatment machine in one of these rooms, one should re-shield the room since it was designed only for 1.25 MeV gamma beams on average. Mostly, the vendor of the new machine constructs the new shielding of the room using their experience. However, every radiotherapy room has different surrounding work areas and it would be wise to shield the room considering these special conditions. Also, the shield design goal of the clinic may be much lower than the International Atomic Energy Agency (IAEA) or the local association accepts. The study shows re-shielding of a Cobalt-60 room, specific to the clinic, using Monte Carlo simulations. Materials & Methods: First, a 6 MV Tomotherapy machine, then a 10 MV conventional linear accelerator (LINAC) was placed inside the Cobalt-60 teletherapy room. The photon flux outside the room was simulated using Monte Carlo N-Particle (MCNP6.1) code before and after re-shielding. For the Tomotherapy simulation, flux distributions around the machine were obtained from the vendor and implemented as the source of the model. The LINAC model was more generic with the 10 MeV electron source, the tungsten target, first and secondary collimators. The aim of the model was to obtain the maximum (40x40 cm2) open field at the isocenter. Two different simulations were carried out for gantry angles 90o and 270o. The LINAC was placed in the room such that the primary walls were A' (Gantry 270o) and C' (Gantry 90o) (figure 1). The second part of the study was to model the re-shielding of the room for Tomotherapy and for the conventional LINAC, separately. The aim was to investigate the recommended shielding by the vendors. Left side of the room was adjacent to a LINAC room with 2 meters thick concrete wall (figure 1). No shielding was necessary for that wall. Behind wall A-A' there was an outdoors forbidden area; behind wall B-B' was the contouring room for the doctors; and the control room was behind wall C-C' (figure 1). After some modifications, the final shielding was designed. Results: The photon flux distributions outside the room before and after the re-shielding were compared. The re-shielding of Tomotherapy reduced the flux down to 1.89 % on average with respect to pre-shielding (table 1). For the conventional LINAC case; after re-shielding, the photon flux in the control room -which corresponds to gantry 90°- decreased down to 0.57% with respect to pre-shielding (table 2). The photon flux behind wall A' -which corresponds to gantry 270°- decreased down to 2.46%. Everybody was all safe behind wall B' even before re-shielding.

PDF modeling of near-wall turbulent flows

NASA Astrophysics Data System (ADS)

Dreeben, Thomas David

1997-06-01

Pdf methods are extended to include modeling of wall- bounded turbulent flows. For flows in which resolution of the viscous sublayer is desired, a Pdf near-wall model is developed in which the Generalized Langevin model is combined with an exact model for viscous transport. Durbin's method of elliptic relaxation is used to incorporate the wall effects into the governing equations without the use of wall functions or damping functions. Close to the wall, the Generalized Langevin model provides an analogy to the effect of the fluctuating continuity equation. This enables accurate modeling of the near-wall turbulent statistics. Demonstrated accuracy for fully-developed channel flow is achieved with a Pdf/Monte Carlo simulation, and with its related Reynolds-stress closure. For flows in which the details of the viscous sublayer are not important, a Pdf wall- function method is developed with the Simplified Langevin model.

Role of Ca++ in Shoot Gravitropism. [avena

NASA Technical Reports Server (NTRS)

Rayle, D. L.

1985-01-01

A cornerstone in the argument that Ca(2+) levels may regulate growth is the finding the EGTA promotes straight growth. The usual explanation for these results is that Ca(2+) chelation from cell walls results in wall loosening and thus accelerated straight growth. The ability of frozen-thawed Avena coleoptile tissue (subjected to 15g tension) to extend in response to EGTA and Quin II was examined. The EGTA when applied in weakly buffered (i.e., 0.1mM) neutral solutions initiates rapid extension. When the buffer strength is increased, similar concentrations of EGTA produce no growth response. This implies when EGTA liberated protons are released upon Ca(2+) chelation they can either initiate acid growth (low buffer conditions) or if consumed (high buffer conditions) have no effect. Thus Ca(2+) chelation in itself apparently does not result in straight growth.

Development of Acceleration Sensor and Acceleration Evaluation System for Super-Low-Range Frequencies

NASA Astrophysics Data System (ADS)

Asano, Shogo; Matsumoto, Hideki

2001-05-01

This paper describes the development process for acceleration sensors used on automobiles and an acceleration evaluation system designed specifically for acceleration at super-low-range frequencies. The features of the newly developed sensor are as follows. 1) Original piezo-bimorph design based on a disc-center-fixed structure achieves pyroeffect cancelling and stabilization of sensor characteristics and enables the detection of the acceleration of 0.0009 G at the super-low-range-frequency of 0.03 Hz. 2) The addition of a self-diagnostic function utilizing the characteristics of piezoceramics enables constant monitoring of sensor failure. The frequency range of acceleration for accurate vehicle motion control is considered to be from DC to about 50 Hz. However, the measurement of acceleration in the super-low-range frequency near DC has been difficult because of mechanical and electrical noise interruption. This has delayed the development of the acceleration sensor for automotive use. We have succeeded in the development of an acceleration evaluation system for super-low-range frequencies from 0.015 Hz to 2 Hz with detection of the acceleration range from 0.0002 G (0.2 gal) to 1 G, as well as the development of a piezoelectric-type acceleration sensor for automotive use.

[Technical Gap of Chinese Medical Accelerator and Its Development Path].

PubMed

Tian, Xinzhi

2017-11-30

With the reform and opening up the tide through nearly four decades of development, our medical accelerator business isfacing new era demands now, in this new historical opportunity in front of the younger generation of medical accelerator staff must assume the older generation of scientific research personnel are different of the historical responsibility. Based on the development of the predecessors, we try to analyze the current situation of the domestic accelerator, establish the new development ideas of the domestic medical accelerator, and directly face and solve the dilemma facing the development of the domestic accelerator.

Collective Acceleration with Rotating Relativistic Electron Beams.

DTIC Science & Technology

1980-04-11

experiments[ where rela- tivistic electron beams were injected into neutral gas filled drift tubes . This paper presents results of recent experiments in...was applied in the drift tube . Rander7 has measured the beamfront velocity, ion yield and ion momentum distribution for non- rotating beams in hydrogen...fields (axial and azimuthal) and currents induced in the drift tube wall.8 Diode voltage and current are V - 900 kV, I - 80 kA for r" - 100 ns, with

Identifying new lignin bioengineering targets: 1. Monolignol-substitute impacts on lignin formation and cell wall fermentability

PubMed Central

2010-01-01

Background Recent discoveries highlighting the metabolic malleability of plant lignification indicate that lignin can be engineered to dramatically alter its composition and properties. Current plant biotechnology efforts are primarily aimed at manipulating the biosynthesis of normal monolignols, but in the future apoplastic targeting of phenolics from other metabolic pathways may provide new approaches for designing lignins that are less inhibitory toward the enzymatic hydrolysis of structural polysaccharides, both with and without biomass pretreatment. To identify promising new avenues for lignin bioengineering, we artificially lignified cell walls from maize cell suspensions with various combinations of normal monolignols (coniferyl and sinapyl alcohols) plus a variety of phenolic monolignol substitutes. Cell walls were then incubated in vitro with anaerobic rumen microflora to assess the potential impact of lignin modifications on the enzymatic degradability of fibrous crops used for ruminant livestock or biofuel production. Results In the absence of anatomical constraints to digestion, lignification with normal monolignols hindered both the rate and extent of cell wall hydrolysis by rumen microflora. Inclusion of methyl caffeate, caffeoylquinic acid, or feruloylquinic acid with monolignols considerably depressed lignin formation and strikingly improved the degradability of cell walls. In contrast, dihydroconiferyl alcohol, guaiacyl glycerol, epicatechin, epigallocatechin, and epigallocatechin gallate readily formed copolymer-lignins with normal monolignols; cell wall degradability was moderately enhanced by greater hydroxylation or 1,2,3-triol functionality. Mono- or diferuloyl esters with various aliphatic or polyol groups readily copolymerized with monolignols, but in some cases they accelerated inactivation of wall-bound peroxidase and reduced lignification; cell wall degradability was influenced by lignin content and the degree of ester group hydroxylation. Conclusion Overall, monolignol substitutes improved the inherent degradability of non-pretreated cell walls by restricting lignification or possibly by reducing lignin hydrophobicity or cross-linking to structural polysaccharides. Furthermore some monolignol substitutes, chiefly readily cleaved bi-phenolic conjugates like epigallocatechin gallate or diferuloyl polyol esters, are expected to greatly boost the enzymatic degradability of cell walls following chemical pretreatment. In ongoing work, we are characterizing the enzymatic saccharification of intact and chemically pretreated cell walls lignified by these and other monolignol substitutes to identify promising genetic engineering targets for improving plant fiber utilization. PMID:20565789

Novelties of the flowering plant pollen tube underlie diversification of a key life history stage.

PubMed

Williams, Joseph H

2008-08-12

The origin and rapid diversification of flowering plants has puzzled evolutionary biologists, dating back to Charles Darwin. Since that time a number of key life history and morphological traits have been proposed as developmental correlates of the extraordinary diversity and ecological success of angiosperms. Here, I identify several innovations that were fundamental to the evolutionary lability of angiosperm reproduction, and hence to their diversification. In gymnosperms pollen reception must be near the egg largely because sperm swim or are transported by pollen tubes that grow at very slow rates (< approximately 20 microm/h). In contrast, pollen tube growth rates of taxa in ancient angiosperm lineages (Amborella, Nuphar, and Austrobaileya) range from approximately 80 to 600 microm/h. Comparative analyses point to accelerated pollen tube growth rate as a critical innovation that preceded the origin of the true closed carpel, long styles, multiseeded ovaries, and, in monocots and eudicots, much faster pollen tube growth rates. Ancient angiosperm pollen tubes all have callosic walls and callose plugs (in contrast, no gymnosperms have these features). The early association of the callose-walled growth pattern with accelerated pollen tube growth rate underlies a striking repeated pattern of faster and longer-distance pollen tube growth often within solid pathways in phylogenetically derived angiosperms. Pollen tube innovations are a key component of the spectacular diversification of carpel (flower and fruit) form and reproductive cycles in flowering plants.

A hybrid chip based on aerodynamics and electrostatics for the size-dependent classification of ultrafine and nano particles.

PubMed

Kim, Yong-Ho; Park, Dongho; Hwang, Jungho; Kim, Yong-Jun

2009-09-21

Conventional virtual impactors experience a large pressure drop when they classify particles according to size, in particular ultrafine particles smaller than 100 nm in diameter. Therefore, most virtual impactors have been used to classify particles larger than 100 nm. Their cut-off diameters are also fixed by the geometry of their flow channels. In the proposed virtual impactor, particles smaller than 100 nm are accelerated by applying DC potentials to an integrated electrode pair. By the electrical acceleration, the large pressure drop could be significantly decreased and new cut-off diameters smaller than 100 nm could be successfully added. The geometric cut-off diameter (GCD) of the proposed virtual impactor was designed to be 1.0 microm. Performances including the GCD and wall loss were examined by classifying dioctyl sebacate of 100 to 600 nm in size and carbon particles of 0.6 to 10 microm in size. The GCD was measured to be 0.95 microm, and the wall loss was highest at 1.1 microm. To add new cut-off diameters, monodisperse NaCl particles ranging from 15 to 70 nm were classified using the proposed virtual impactor with applying a DC potential of 0.25 to 3.0 kV. In this range of the potential, the new cut-off diameters ranging from 15 to 35 nm was added.

A resolvable subfilter-scale model specific to large-eddy simulation of under-resolved turbulence

NASA Astrophysics Data System (ADS)

Zhou, Yong; Brasseur, James G.; Juneja, Anurag

2001-09-01

Large-eddy simulation (LES) of boundary-layer flows has serious deficiencies near the surface when a viscous sublayer either does not exist (rough walls) or is not practical to resolve (high Reynolds numbers). In previous work, we have shown that the near-surface errors arise from the poor performance of algebraic subfilter-scale (SFS) models at the first several grid levels, where integral scales are necessarily under-resolved and the turbulence is highly anisotropic. In under-resolved turbulence, eddy viscosity and similarity SFS models create a spurious feedback loop between predicted resolved-scale (RS) velocity and modeled SFS acceleration, and are unable to simultaneously capture SFS acceleration and RS-SFS energy flux. To break the spurious coupling in a dynamically meaningful manner, we introduce a new modeling strategy in which the grid-resolved subfilter velocity is estimated from a separate dynamical equation containing the essential inertial interactions between SFS and RS velocity. This resolved SFS (RSFS) velocity is then used as a surrogate for the complete SFS velocity in the SFS stress tensor. We test the RSFS model by comparing LES of highly under-resolved anisotropic buoyancy-generated homogeneous turbulence with a corresponding direct numerical simulation (DNS). The new model successfully suppresses the spurious feedback loop between RS velocity and SFS acceleration, and greatly improves model predictions of the anisotropic structure of SFS acceleration and resolved velocity fields. Unlike algebraic models, the RSFS model accurately captures SFS acceleration intensity and RS-SFS energy flux, even during the nonequilibrium transient, and properly partitions SFS acceleration between SFS stress divergence and SFS pressure force.

Hierarchical algorithms for modeling the ocean on hierarchical architectures

NASA Astrophysics Data System (ADS)

Hill, C. N.

2012-12-01

This presentation will describe an approach to using accelerator/co-processor technology that maps hierarchical, multi-scale modeling techniques to an underlying hierarchical hardware architecture. The focus of this work is on making effective use of both CPU and accelerator/co-processor parts of a system, for large scale ocean modeling. In the work, a lower resolution basin scale ocean model is locally coupled to multiple, "embedded", limited area higher resolution sub-models. The higher resolution models execute on co-processor/accelerator hardware and do not interact directly with other sub-models. The lower resolution basin scale model executes on the system CPU(s). The result is a multi-scale algorithm that aligns with hardware designs in the co-processor/accelerator space. We demonstrate this approach being used to substitute explicit process models for standard parameterizations. Code for our sub-models is implemented through a generic abstraction layer, so that we can target multiple accelerator architectures with different programming environments. We will present two application and implementation examples. One uses the CUDA programming environment and targets GPU hardware. This example employs a simple non-hydrostatic two dimensional sub-model to represent vertical motion more accurately. The second example uses a highly threaded three-dimensional model at high resolution. This targets a MIC/Xeon Phi like environment and uses sub-models as a way to explicitly compute sub-mesoscale terms. In both cases the accelerator/co-processor capability provides extra compute cycles that allow improved model fidelity for little or no extra wall-clock time cost.

Projected Improvements in Accelerated Partial Breast Irradiation Using a Novel Breast Stereotactic Radiotherapy Device: A Dosimetric Analysis.

PubMed

Snider, James W; Mutaf, Yildirim; Nichols, Elizabeth; Hall, Andrea; Vadnais, Patrick; Regine, William F; Feigenberg, Steven J

2017-01-01

Accelerated partial breast irradiation has caused higher than expected rates of poor cosmesis. At our institution, a novel breast stereotactic radiotherapy device has demonstrated dosimetric distributions similar to those in brachytherapy. This study analyzed comparative dose distributions achieved with the device and intensity-modulated radiation therapy accelerated partial breast irradiation. Nine patients underwent computed tomography simulation in the prone position using device-specific immobilization on an institutional review board-approved protocol. Accelerated partial breast irradiation target volumes (planning target volume_10mm) were created per the National Surgical Adjuvant Breast and Bowel Project B-39 protocol. Additional breast stereotactic radiotherapy volumes using smaller margins (planning target volume_3mm) were created based on improved immobilization. Intensity-modulated radiation therapy and breast stereotactic radiotherapy accelerated partial breast irradiation plans were separately generated for appropriate volumes. Plans were evaluated based on established dosimetric surrogates of poor cosmetic outcomes. Wilcoxon rank sum tests were utilized to contrast volumes of critical structures receiving a percentage of total dose ( Vx). The breast stereotactic radiotherapy device consistently reduced dose to all normal structures with equivalent target coverage. The ipsilateral breast V20-100 was significantly reduced ( P < .05) using planning target volume_10mm, with substantial further reductions when targeting planning target volume_3mm. Doses to the chest wall, ipsilateral lung, and breast skin were also significantly lessened. The breast stereotactic radiotherapy device's uniform dosimetric improvements over intensity-modulated accelerated partial breast irradiation in this series indicate a potential to improve outcomes. Clinical trials investigating this benefit have begun accrual.

Radiation predictions and shielding calculations for RITS-6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maenchen, John Eric; O'Malley, John; Kensek, Ronald Patrick

2005-06-01

The mission of Radiographic Integrated Test Stand-6 (RITS-6) facility is to provide the underlying science and technology for pulsed-power-driven flash radiographic X-ray sources for the National Nuclear Security Administration (NNSA). Flash X-ray radiography is a penetrating diagnostic to discern the internal structure in dynamic experiments. Short (~50 nanosecond (ns) duration) bursts of very high intensity Xrays from mm-scale source sizes are required at a variety of voltages to address this mission. RITS-6 was designed and is used to both develop the accelerator technology needed for these experiments and serves as the principal test stand to develop the high intensity electronmore » beam diodes that generate the required X-ray sources. RITS is currently in operation with three induction cavities (RITS-3) with a maximum voltage output of 5.5 MV and is classified as a low hazard non-nuclear facility in accordance with CPR 400.1.1, Chapter 13, Hazards Identification/Analysis and Risk Management. The facility will be expanded from three to six cavities (RITS-6) effectively doubling the operating voltage. The increase in the operating voltage to above 10 MV has resulted in RITS-6 being classified as an accelerator facility. RITS-6 will come under DOE Order 420.2B, Safety of Accelerator Facilities. The hazards of RITS are detailed in the "Safety Assessment Document for the Radiographic Integrated Test Stand Facility." The principal non-industrial hazard is prompt x-ray radiation. As the operating voltage is increased, both the penetration power and the total amount (dose) of x-rays are increased, thereby increasing the risk to local personnel. Fixed site shielding (predominantly concrete walls and a steel/lead skyshine shield) is used to attenuate these x-rays and mitigate this risk. This SAND Report details the anticipated x-ray doses, the shielding design, and the anticipated x-ray doses external to this shielding structure both in areas where administrative access control restricts occupation and in adjacent uncontrolled areas.« less

Evolutionary origins of pectin methylesterase genes associated with novel aspects of angiosperm pollen tube walls.

PubMed

Wallace, Simon; Williams, Joseph H

2017-06-03

The early evolution of angiosperms was marked by a number of innovations of the reproductive cycle including an accelerated fertilization process involving faster transport of sperm to the egg via a pollen tube. Fast pollen tube growth rates in angiosperms are accompanied by a hard shank-soft tip pollen tube morphology. A critical actor in that morphology is the wall-embedded enzyme pectin methylesterase (PME), which in type II PMEs is accompanied by a co-transcribed inhibitor, PMEI. PMEs convert the esterified pectic tip wall to a stiffer state in the subapical flank by pectin de-esterification. It is hypothesized that rapid and precise targeting of PME activity was gained with the origin of type II genes, which are derived and have only expanded since the origin of vascular plants. Pollen-active PMEs have yet to be reported in early-divergent angiosperms or gymnosperms. Gene expression studies in Nymphaea odorata found transcripts from four type II VGD1-like and 16 type I AtPPME1-like homologs that were more abundant in pollen and pollen tubes than in vegetative tissues. The near full-length coding sequence of one type II PME (NoPMEII-1) included at least one PMEI domain. The identification of possible VGD1 homologs in an early-diverging angiosperm suggests that the refined control of PMEs that mediate de-esterification of pectins near pollen tube tips is a conserved feature across angiosperms. The recruitment of type II PMEs into a pollen tube elongation role in angiosperms may represent a key evolutionary step in the development of faster growing pollen tubes. Copyright © 2017 Elsevier Inc. All rights reserved.

Contribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis

PubMed Central

Loppnow, Harald; Buerke, Michael; Werdan, Karl; Rose-John, Stefan

2011-01-01

Abstract Inflammation is a central element of atherogenesis. Innate pathways contribute to vascular inflammation. However, the initial molecular process(es) starting atherogenesis remain elusive. The various risk factors, represented by particular compounds (activators), may cause altered cellular functions in the endothelium (e.g. vascular endothelial cell activation or -dysfunction), in invading cells (e.g. inflammatory mediator production) or in local vessel wall cells (e.g. inflammatory mediators, migration), thereby triggering the innate inflammatory process. The cellular components of innate immunology include granulocytes, natural killer cells and monocytes. Among the molecular innate constituents are innate molecules, such as the toll-like receptors or innate cytokines. Interleukin-1 (IL-1) and IL-6 are among the innate cytokines. Cytokines are potent activators of a great number of cellular functions relevant to maintain or commove homeostasis of the vessel wall. Within the vessel wall, vascular smooth muscle cells (SMCs) can significantly contribute to the cytokine-dependent inflammatory network by: (i) production of cytokines, (ii) response to cytokines and (iii) cytokine-mediated interaction with invading leucocytes. The cytokines IL-1 and IL-6 are involved in SMC-leucocyte interaction. The IL-6 effects are proposed to be mediated by trans-signalling. Dysregulated cellular functions resulting from dysregulated cytokine production may be the cause of cell accumulation, subsequent low-density lipoprotein accumulation and deposition of extracellular matrix (ECM). The deposition of ECM, increased accumulation of leucocytes and altered levels of inflammatory mediators may constitute an ‘innate-immunovascular-memory’ resulting in an ever-growing response to anew invasion. Thus, SMC-fostered inflammation, promoted by invading innate cells, may be a potent component for development and acceleration of atherosclerosis. PMID:21199323

Molecular control of wood formation in trees.

PubMed

Ye, Zheng-Hua; Zhong, Ruiqin

2015-07-01

Wood (also termed secondary xylem) is the most abundant biomass produced by plants, and is one of the most important sinks for atmospheric carbon dioxide. The development of wood begins with the differentiation of the lateral meristem, vascular cambium, into secondary xylem mother cells followed by cell expansion, secondary wall deposition, programmed cell death, and finally heartwood formation. Significant progress has been made in the past decade in uncovering the molecular players involved in various developmental stages of wood formation in tree species. Hormonal signalling has been shown to play critical roles in vascular cambium cell proliferation and a peptide-receptor-transcription factor regulatory mechanism similar to that controlling the activity of apical meristems is proposed to be involved in the maintenance of vascular cambium activity. It has been demonstrated that the differentiation of vascular cambium into xylem mother cells is regulated by plant hormones and HD-ZIP III transcription factors, and the coordinated activation of secondary wall biosynthesis genes during wood formation is mediated by a transcription network encompassing secondary wall NAC and MYB master switches and their downstream transcription factors. Most genes encoding the biosynthesis enzymes for wood components (cellulose, xylan, glucomannan, and lignin) have been identified in poplar and a number of them have been functionally characterized. With the availability of genome sequences of tree species from both gymnosperms and angiosperms, and the identification of a suite of wood-associated genes, it is expected that our understanding of the molecular control of wood formation in trees will be greatly accelerated. © The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Contact activation of blood coagulation on a defined kaolin/collagen surface in a microfluidic assay.

PubMed

Zhu, Shu; Diamond, Scott L

2014-12-01

Generation of active Factor XII (FXIIa) triggers blood clotting on artificial surfaces and may also enhance intravascular thrombosis. We developed a patterned kaolin (0 to 0.3 pg/μm(2))/type 1 collagen fibril surface for controlled microfluidic clotting assays. Perfusion of whole blood (treated only with a low level of 4 μg/mL of the XIIa inhibitor, corn trypsin inhibitor) drove platelet deposition followed by fibrin formation. At venous wall shear rate (100 s(-1)), kaolin accelerated onset of fibrin formation by ~100 sec when compared to collagen alone (250 sec vs. 350 sec), with little effect on platelet deposition. Even with kaolin present, arterial wall shear rate (1000 s(-1)) delayed and suppressed fibrin formation compared to venous wall shear rate. A comparison of surfaces for extrinsic activation (tissue factor TF/collagen) versus contact activation (kaolin/collagen) that each generated equal platelet deposition at 100 s(-1) revealed: (1) TF surfaces promoted much faster fibrin onset (at 100 sec) and more endpoint fibrin at 600 sec at either 100 s(-1) or 1000 s(-1), and (2) kaolin and TF surfaces had a similar sensitivity for reduced fibrin deposition at 1000 s(-1) (compared to fibrin formed at 100 s(-1)) despite differing coagulation triggers. Anti-platelet drugs inhibiting P2Y1, P2Y12, cyclooxygenase-1 or activating IP-receptor or guanylate cyclase reduced platelet and fibrin deposition on kaolin/collagen. Since FXIIa or FXIa inhibition may offer safe antithrombotic therapy, especially for biomaterial thrombosis, these defined collagen/kaolin surfaces may prove useful in drug screening tests or in clinical diagnostic assays of blood under flow conditions. Copyright © 2014 Elsevier Ltd. All rights reserved.

Predicting oxidation-limited lifetime of thin-walled components of NiCrW alloy 230

DOE PAGES

Duan, R.; Jalowicka, Aleksandra; Unocic, Kinga A.; ...

2016-10-18

Using alloy 230 as an example, a generalized oxidation lifetime model for chromia-forming Ni-base wrought alloys is proposed, which captures the most important damaging oxidation effects relevant for component design: wall thickness loss, scale spallation, and the occurrence of breakaway oxidation. For deriving input parameters and for verification of the model approach, alloy 230 specimens with different thicknesses were exposed for different times at temperatures in the range 950–1050 °C in static air. The studies focused on thin specimens (0.2–0.5 mm) to obtain data for critical subscale depletion processes resulting in breakaway oxidation within reasonably achievable test times up tomore » 3000 h. The oxidation kinetics and oxidation-induced subscale microstructural changes were determined by combining gravimetric data with results from scanning electron microscopy with energy dispersive X-ray spectroscopy. The modeling of the scale spallation and re-formation was based on the NASA cyclic oxidation spallation program, while a new model was developed to describe accelerated oxidation occurring after longer exposure times in the thinnest specimens. The calculated oxidation data were combined with the reservoir model equation, by means of which the relation between the consumption and the remaining concentration of Cr in the alloy was established as a function of temperature and specimen thickness. Based on this approach, a generalized lifetime diagram is proposed, in which wall thickness loss is plotted as a function of time, initial specimen thickness, and temperature. As a result, the time to reach a critical Cr level at the scale/alloy interface of 10 wt% is also indicated in the diagrams.« less

Analytic Modeling of Pressurization and Cryogenic Propellant

NASA Technical Reports Server (NTRS)

Corpening, Jeremy H.

2010-01-01

An analytic model for pressurization and cryogenic propellant conditions during all mission phases of any liquid rocket based vehicle has been developed and validated. The model assumes the propellant tanks to be divided into five nodes and also implements an empirical correlation for liquid stratification if desired. The five nodes include a tank wall node exposed to ullage gas, an ullage gas node, a saturated propellant vapor node at the liquid-vapor interface, a liquid node, and a tank wall node exposed to liquid. The conservation equations of mass and energy are then applied across all the node boundaries and, with the use of perfect gas assumptions, explicit solutions for ullage and liquid conditions are derived. All fluid properties are updated real time using NIST Refprop.1 Further, mass transfer at the liquid-vapor interface is included in the form of evaporation, bulk boiling of liquid propellant, and condensation given the appropriate conditions for each. Model validation has proven highly successful against previous analytic models and various Saturn era test data and reasonably successful against more recent LH2 tank self pressurization ground test data. Finally, this model has been applied to numerous design iterations for the Altair Lunar Lander, Ares V Core Stage, and Ares V Earth Departure Stage in order to characterize Helium and autogenous pressurant requirements, propellant lost to evaporation and thermodynamic venting to maintain propellant conditions, and non-uniform tank draining in configurations utilizing multiple LH2 or LO2 propellant tanks. In conclusion, this model provides an accurate and efficient means of analyzing multiple design configurations for any cryogenic propellant tank in launch, low-acceleration coast, or in-space maneuvering and supplies the user with pressurization requirements, unusable propellants from evaporation and liquid stratification, and general ullage gas, liquid, and tank wall conditions as functions of time.

Predicting oxidation-limited lifetime of thin-walled components of NiCrW alloy 230

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duan, R.; Jalowicka, Aleksandra; Unocic, Kinga A.

Using alloy 230 as an example, a generalized oxidation lifetime model for chromia-forming Ni-base wrought alloys is proposed, which captures the most important damaging oxidation effects relevant for component design: wall thickness loss, scale spallation, and the occurrence of breakaway oxidation. For deriving input parameters and for verification of the model approach, alloy 230 specimens with different thicknesses were exposed for different times at temperatures in the range 950–1050 °C in static air. The studies focused on thin specimens (0.2–0.5 mm) to obtain data for critical subscale depletion processes resulting in breakaway oxidation within reasonably achievable test times up tomore » 3000 h. The oxidation kinetics and oxidation-induced subscale microstructural changes were determined by combining gravimetric data with results from scanning electron microscopy with energy dispersive X-ray spectroscopy. The modeling of the scale spallation and re-formation was based on the NASA cyclic oxidation spallation program, while a new model was developed to describe accelerated oxidation occurring after longer exposure times in the thinnest specimens. The calculated oxidation data were combined with the reservoir model equation, by means of which the relation between the consumption and the remaining concentration of Cr in the alloy was established as a function of temperature and specimen thickness. Based on this approach, a generalized lifetime diagram is proposed, in which wall thickness loss is plotted as a function of time, initial specimen thickness, and temperature. As a result, the time to reach a critical Cr level at the scale/alloy interface of 10 wt% is also indicated in the diagrams.« less

Water pressure and ground vibrations induced by water guns near Bandon Road Lock and Dam and Lemont, Illinois

USGS Publications Warehouse

Adams, Ryan F.; Koebel, Carolyn M.; Morrow, William S.

2018-02-13

Multiple geophysical sensors were used to characterize the underwater pressure field and ground vibrations of a seismic water gun and its suitability to deter the movement of Asian carps (particularly the silver [Hypophthalmichthys molitrix] and bighead [Hypophthalmichthys nobilis] carps) while ensuring the integrity of surrounding structures. The sensors used to collect this information were blast-rated hydrophones, surface- and borehole-mounted geophones, and fixed accelerometers.Results from two separate studies are discussed in this report. The Brandon Road study took place in May 2014, in the Des Plaines River, in a concrete-walled channel downstream of the Brandon Road Lock and Dam near Joliet, Illinois. The Lemont study took place in June 2014, in a segment of the dolomite setblock-lined Chicago Sanitary and Ship Canal near Lemont, Illinois.Two criteria were evaluated to assess the potential deterrence to carp migration, and to minimize the expected effect on nearby structures from discharge of the seismic water gun. The first criterion was a 5-pound-per-square-inch (lb/in2) limit for dynamic underwater pressure variations. The second criterion was a maximum velocity and acceleration disturbance of 0.75 inch per second (in/s) for sensitive machinery (such as the lock gates and pumps) and 2.0 in/s adjacent to canal walls, respectively. The criteria were based on previous studies of fish responses to dynamic pressure variations, and effects of vibrations on the structural integrity of concrete walls.The Brandon Road study evaluated the magnitude and extent of the pressure field created by two water gun configurations in the concrete-walled channel downstream of the lock where channel depths ranged from 11 to 14 feet (ft). Data from a single 80-cubic-inch (in³) water gun set at 6 ft below water surface (bws) produced a roughly cylindrical 5-lb/in2 pressure field 20 ft in radius, oriented vertically, with the radius decreasing to less than 15 ft at the water surface. A combination of two 80-in3 water guns set at 6 and 8 ft, respectively, produced a similarly shaped 5 lb/in2 pressure field 30 ft in radius. Neither of the water gun configurations exceeded the given threshold of 5 lb/in2 above the static pressure along the walls of the canal at the 700 lb/in2 water gun input pressure. Velocity and acceleration data were collected simultaneously with the underwater pressure data to understand the response of adjacent canal walls to the water gun firings. Maximum velocity and acceleration were 0.239 in/s and 0.0188 feet per second squared (ft/s2), respectively.The Lemont study replicated and expanded upon work done in 2011. The pressure field created by the water gun was evaluated in a deeper environment (about 25 ft of water depth) than that of the Brandon Road study. To replicate the 2011 study, data were collected with the same water gun placements and input pressure, but static underwater pressure monitoring was added. Two 80-in3 water guns were suspended below a platform at depths of 4 and 14 ft bws. Pressure was lower when the gun suspended at 4 ft bws was fired as compared to firing the single gun suspended at 14 ft bws. Firing both guns simultaneously produced similar pressures to the single gun suspended at 14 ft bws. Data were collected to assess the pressure field produced by two 80-in3 water guns separated by 80 ft and suspended at a depth of 14 ft bws. The spatial extent of the 5-lb/in2 threshold varied substantially with gun input air pressure. Firing the water gun with an air pressure of 2,000 lb/in2 generated a pressure field greater than the threshold at all but one location in the measured region. Additionally, the water gun with an air pressure of 1,000 lb/in2 did not reach the threshold anywhere in the measured region. Maximum velocity and acceleration were 0.304 in/s and 0.015 ft/s2, respectively.

Fine-grained parallelism accelerating for RNA secondary structure prediction with pseudoknots based on FPGA.

PubMed

Xia, Fei; Jin, Guoqing

2014-06-01

PKNOTS is a most famous benchmark program and has been widely used to predict RNA secondary structure including pseudoknots. It adopts the standard four-dimensional (4D) dynamic programming (DP) method and is the basis of many variants and improved algorithms. Unfortunately, the O(N(6)) computing requirements and complicated data dependency greatly limits the usefulness of PKNOTS package with the explosion in gene database size. In this paper, we present a fine-grained parallel PKNOTS package and prototype system for accelerating RNA folding application based on FPGA chip. We adopted a series of storage optimization strategies to resolve the "Memory Wall" problem. We aggressively exploit parallel computing strategies to improve computational efficiency. We also propose several methods that collectively reduce the storage requirements for FPGA on-chip memory. To the best of our knowledge, our design is the first FPGA implementation for accelerating 4D DP problem for RNA folding application including pseudoknots. The experimental results show a factor of more than 50x average speedup over the PKNOTS-1.08 software running on a PC platform with Intel Core2 Q9400 Quad CPU for input RNA sequences. However, the power consumption of our FPGA accelerator is only about 50% of the general-purpose micro-processors.

In situ baking method for degassing of a kicker magnet in accelerator beam line

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kamiya, Junichiro, E-mail: kamiya.junichiro@jaea.go.jp; Ogiwara, Norio; Yanagibashi, Toru

In this study, the authors propose a new in situ degassing method by which only kicker magnets in the accelerator beam line are baked out without raising the temperature of the vacuum chamber to prevent unwanted thermal expansion of the chamber. By simply installing the heater and thermal radiation shield plates between the kicker magnet and the chamber wall, most of the heat flux from the heater directs toward the kicker magnet. The result of the verification test showed that each part of the kicker magnet was heated to above the target temperature with a small rise in the vacuummore » chamber temperature. A graphite heater was selected in this application to bake-out the kicker magnet in the beam line to ensure reliability and easy maintainability of the heater. The vacuum characteristics of graphite were suitable for heater operation in the beam line. A preliminary heat-up test conducted in the accelerator beam line also showed that each part of the kicker magnet was successfully heated and that thermal expansion of the chamber was negligibly small.« less

Characterizing Laminar Flame Interactions with Turbulent Fluidic Jets and Solid Obstacles for Turbulence Induction

NASA Astrophysics Data System (ADS)

Gerdts, Stephen; Chambers, Jessica; Ahmed, Kareem

2016-11-01

A detonation engine's fundamental design concept focuses on enhancing the Deflagration to Detonation Transition (DDT), the process through which subsonic flames accelerate to form a spontaneous detonation wave. Flame acceleration is driven by turbulent interactions that expand the reaction zone and induce mixing of products and reactants. Turbulence in a duct can be generated using solid obstructions, fluidic obstacles, duct angle changes, and wall skin friction. Solid obstacles have been previously explored and offer repeatable turbulence induction at the cost of pressure losses and additional system weight. Fluidic jet obstacles are a novel technique that provide advantages such as the ability to be throttled, allowing for active control of combustion modes. The scope of the present work is to expand the experimental database of varying parameters such as main flow and jet equivalence ratios, fluidic momentum ratios, and solid obstacle blockage ratios. Schlieren flow visualization and particle image velocimetry (PIV) are employed to investigate turbulent flame dynamics throughout the interaction. Optimum conditions that lead to flame acceleration for both solid and fluidic obstacles will be determined. American Chemical Society.

Superconducting magnets for the RAON electron cyclotron resonance ion source.

PubMed

Choi, S; Kim, Y; Hong, I S; Jeon, D

2014-02-01

The RAON linear accelerator of Rare Isotope Science Project has been developed since 2011, and the superconducting magnet for ECRIS was designed. The RAON ECR ion source was considered as a 3rd generation source. The fully superconducting magnet has been designed for operating using 28 GHz radio frequency. The RAON ECRIS operates in a minimum B field configuration which means that a magnetic sextupole field for radial confinement is superimposed with a magnetic mirror field for axial confinement. The highest field strength reaches 3.5 T on axis and 2 T at the plasma chamber wall for operating frequency up to 28 GHz. In this paper, the design results are presented of optimized superconducting magnet consisting of four solenoids and sextupole. The prototype magnet for ECRIS was fabricated and tested to verify the feasibility of the design. On the basis of test results, a fully superconducting magnet will be fabricated and tested.

Roos and NACP-02 ion chamber perturbations and water-air stopping-power ratios for clinical electron beams for energies from 4 to 22 MeV

NASA Astrophysics Data System (ADS)

Bailey, M.; Shipley, D. R.; Manning, J. W.

2015-02-01

Empirical fits are developed for depth-compensated wall- and cavity-replacement perturbations in the PTW Roos 34001 and IBA / Scanditronix NACP-02 parallel-plate ionisation chambers, for electron beam qualities from 4 to 22 MeV for depths up to approximately 1.1 × R50,D. These are based on calculations using the Monte Carlo radiation transport code EGSnrc and its user codes with a full simulation of the linac treatment head modelled using BEAMnrc. These fits are used with calculated restricted stopping-power ratios between air and water to match measured depth-dose distributions in water from an Elekta Synergy clinical linear accelerator at the UK National Physical Laboratory. Results compare well with those from recent publications and from the IPEM 2003 electron beam radiotherapy Code of Practice.

Pathogenesis of hypertensive retinopathy. An experimental study in the monkey.

PubMed Central

Garner, A; Ashton, N; Tripathi, R; Kohner, E M; Bulpitt, C J; Dollery, C T

1975-01-01

Retinal changes in accelerated hypertension were studied in seventeen monkeys with experimental hypertension by means of ophthalmoscopy and colour and flourescence photography during life, and by injection and digest preparations and light and electron microscopy after the animals had been killed. Cotton-wool spots developed in all but three monkeys. The arteries became tortuous and dilated and the light reflex decreased in those animals that became hypertensive. The earliest abnormality was a development of many points of fluorescein leakage on terminal arterioles or small arteries. Such leaking points were always present in relation to cotton-wool spots but were not confined to such areas. Focal narrowing of arteries was not observed but arteriolar occlusion and retrograde filling of the distal segment was present in three animals. Superficial linear haemorrhages were noted in five animals. Light microscopy revealed cotton-wool spots which were identical to those observed in man with a collection of swollen axons containing densely staining pseudonuclei. Study of the arterioles by electron microscopy showed findings ranging from normality to extensive necrosis. Many precapillary arteries were constricted and some were virtually occluded. Degenerative changes were present in smooth muscle cells in the wall of many of the constricted arterioles. Many arteries also showed insudation into their wall of plasma which had seeped into the muscular coat displacing and sometimes entirely replacing the smooth muscle cells. Except for arterioles with advanced necrosis, there was no indication of how plasma insudation occurred. Two arterioles with extensive necrosis showed a break within the endothelial cell cytoplasm through which penetration of plasma proteins had probably occurred. The extravascular tissues showed collections of amorphous material, sone of it with the typical banded configuration of fibrin. The sequence of events proposed to explain these features is as follows: (1) The arterioles constrict as the pressure rises, most likely as a result of vascular autoregulation. This may head to occlusion of the precapillary arterioles and is associated with necrosis of vascular smooth muscle. (2) Dilatation then occurs with insudation of plasma into the unsupported wall through a damaged endothelium. This stage probably corresponds to the autoregulatory break-point and is evidenced clinically by focal leakage of fluorescein. (3) Progressive plasma insudation into the vessel wall with further muscle necrosis results in secondary occlusion and the typical picture of advanced fibrinoid necrosis. Images PMID:804913

Background gas density and beam losses in NIO1 beam source

NASA Astrophysics Data System (ADS)

Sartori, E.; Veltri, P.; Cavenago, M.; Serianni, G.

2016-02-01

NIO1 (Negative Ion Optimization 1) is a versatile ion source designed to study the physics of production and acceleration of H- beams up to 60 keV. In ion sources, the gas is steadily injected in the plasma source to sustain the discharge, while high vacuum is maintained by a dedicated pumping system located in the vessel. In this paper, the three dimensional gas flow in NIO1 is studied in the molecular flow regime by the Avocado code. The analysis of the gas density profile along the accelerator considers the influence of effective gas temperature in the source, of the gas temperature accommodation by collisions at walls, and of the gas particle mass. The calculated source and vessel pressures are compared with experimental measurements in NIO1 during steady gas injection.

Means for obtaining a metal ion beam from a heavy-ion cyclotron source

DOEpatents

Hudson, E.D.; Mallory, M.L.

1975-08-01

A description is given of a modification to a cyclotron ion source used in producing a high intensity metal ion beam. A small amount of an inert support gas maintains the usual plasma arc, except that it is necessary for the support gas to have a heavy mass, e.g., xenon or krypton as opposed to neon. A plate, fabricated from the metal (or anything that can be sputtered) to be ionized, is mounted on the back wall of the ion source arc chamber and is bombarded by returning energetic low-charged gas ions that fail to cross the initial accelerating gap between the ion source and the accelerating electrode. Some of the atoms that are dislodged from the plate by the returning gas ions become ionized and are extracted as a useful beam of heavy ions. (auth)

Resistive anode image converter

NASA Technical Reports Server (NTRS)

Lampton, M. L.; Paresce, F. (Inventor)

1976-01-01

The invention of an apparatus for imaging soft X-ray and ultraviolet electromagnetic radiation and charged particles was described. The apparatus includes a pair of microchannel electron multiplier plates connected in a cascaded chevron configuration which intercepts an incident beam of radiation or charged particles. Incident photons or charged particles strike the front surface of the chevron configuration causing emission of electrons. The electrons are accelerated by a voltage gradient and strike the inner side walls of the individual channels, causing emission of secondary electrons. Accelerated and multiplied secondary electrons impinge upon a resistive anode after they transverse the chevron configuration. A pulse position circuit converts the magnitude or transit time of the currents flowing from the point of impact of the electrons on the resistive anode to four contact electrodes mounted on their periphery of the resistive anode into the spatial coordinates of electron impact.

A Near-Wall Reynolds-Stress Closure without Wall Normals

NASA Technical Reports Server (NTRS)

Yuan, S. P.; So, R. M. C.

1997-01-01

With the aid of near-wall asymptotic analysis and results of direct numerical simulation, a new near-wall Reynolds stress model (NNWRS) is formulated based on the SSG high-Reynolds-stress model with wall-independent near-wall corrections. Only one damping function is used for flows with a wide range of Reynolds numbers to ensure that the near-wall modifications diminish away from the walls. The model is able to reproduce complicated flow phenomena induced by complex geometry, such as flow recirculation, reattachment and boundary-layer redevelopment in backward-facing step flow and secondary flow in three-dimensional square duct flow. In simple flows, including fully developed channel/pipe flow, Couette flow and boundary-layer flow, the wall effects are dominant, and the NNWRS model predicts less degree of turbulent anisotropy in the near-wall region compared with a wall-dependent near-wall Reynolds Stress model (NWRS) developed by So and colleagues. The comparison of the predictions given by the two models rectifies the misconception that the overshooting of skin friction coefficient in backward-facing step flow prevalent in those near-wall, models with wall normal is caused by he use of wall normal.

Graduate Student Program in Materials and Engineering Research and Development for Future Accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spentzouris, Linda

The objective of the proposal was to develop graduate student training in materials and engineering research relevant to the development of particle accelerators. Many components used in today's accelerators or storage rings are at the limit of performance. The path forward in many cases requires the development of new materials or fabrication techniques, or a novel engineering approach. Often, accelerator-based laboratories find it difficult to get top-level engineers or materials experts with the motivation to work on these problems. The three years of funding provided by this grant was used to support development of accelerator components through a multidisciplinary approachmore » that cut across the disciplinary boundaries of accelerator physics, materials science, and surface chemistry. The following results were achieved: (1) significant scientific results on fabrication of novel photocathodes, (2) application of surface science and superconducting materials expertise to accelerator problems through faculty involvement, (3) development of instrumentation for fabrication and characterization of materials for accelerator components, (4) student involvement with problems at the interface of material science and accelerator physics.« less

Electron Production and Collective Field Generation in Intense Particle Beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Molvik, A W; Vay, J; Cohen, R

Electron cloud effects (ECEs) are increasingly recognized as important, but incompletely understood, dynamical phenomena, which can severely limit the performance of present electron colliders, the next generation of high-intensity rings, such as PEP-II upgrade, LHC, and the SNS, the SIS 100/200, or future high-intensity heavy ion accelerators such as envisioned in Heavy Ion Inertial Fusion (HIF). Deleterious effects include ion-electron instabilities, emittance growth, particle loss, increase in vacuum pressure, added heat load at the vacuum chamber walls, and interference with certain beam diagnostics. Extrapolation of present experience to significantly higher beam intensities is uncertain given the present level of understanding.more » With coordinated LDRD projects at LLNL and LBNL, we undertook a comprehensive R&D program including experiments, theory and simulations to better understand the phenomena, establish the essential parameters, and develop mitigating mechanisms. This LDRD project laid the essential groundwork for such a program. We developed insights into the essential processes, modeled the relevant physics, and implemented these models in computational production tools that can be used for self-consistent study of the effect on ion beams. We validated the models and tools through comparison with experimental data, including data from new diagnostics that we developed as part of this work and validated on the High-Current Experiment (HCX) at LBNL. We applied these models to High-Energy Physics (HEP) and other advanced accelerators. This project was highly successful, as evidenced by the two paragraphs above, and six paragraphs following that are taken from our 2003 proposal with minor editing that mostly consisted of changing the tense. Further benchmarks of outstanding performance are: we had 13 publications with 8 of them in refereed journals, our work was recognized by the accelerator and plasma physics communities by 8 invited papers and we have 5 additional invitations for invited papers at upcoming conferences, we attracted collaborators who had SBIR funding, we are collaborating with scientists at CERN and GSI Darmstadt on gas desorption physics for submission to Physical Review Letters, and another PRL on absolute measurements of electron cloud density and Phys. Rev. ST-AB on electron emission physics are also being readied for submission.« less

The design and operational development of self-streamlining 2-dimensional flexible walled test sections. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Wolf, S. W. D.

1984-01-01

Self streamlining two dimensional flexible walled test sections eliminate the uncertainties found in data from conventional test sections particularly at transonic speeds. The test section sidewalls are rigid, while the floor and ceiling are flexible and are positioned to streamline shapes by a system of jacks, without reference to the model. The walls are therefore self streamlining. Data are taken from the model when the walls are good streamlines such that the inevitable residual wall induced interference is acceptably small and correctable. Successful two dimensional validation testing at low speeds has led to the development of a new transonic flexible walled test section. Tunnel setting times are minimized by the development of a rapid wall setting strategy coupled with on line computer control of wall shapes using motorized jacks. Two dimensional validation testing using symmetric and cambered aerofoils in the Mach number range up to about 0.85 where the walls are just supercritical, shows good agreement with reference data using small height-chord ratios between 1.5 and unity.

Two Complementary Mechanisms Underpin Cell Wall Patterning during Xylem Vessel Development[OPEN

PubMed Central

Tang, Lu; Barkwill, Sarah; Lathe, Rahul; McFarlane, Heather E.

2017-01-01

The evolution of the plant vasculature was essential for the emergence of terrestrial life. Xylem vessels are solute-transporting elements in the vasculature that possess secondary wall thickenings deposited in intricate patterns. Evenly dispersed microtubule (MT) bands support the formation of these wall thickenings, but how the MTs direct cell wall synthesis during this process remains largely unknown. Cellulose is the major secondary wall constituent and is synthesized by plasma membrane-localized cellulose synthases (CesAs) whose catalytic activity propels them through the membrane. We show that the protein CELLULOSE SYNTHASE INTERACTING1 (CSI1)/POM2 is necessary to align the secondary wall CesAs and MTs during the initial phase of xylem vessel development in Arabidopsis thaliana and rice (Oryza sativa). Surprisingly, these MT-driven patterns successively become imprinted and sufficient to sustain the continued progression of wall thickening in the absence of MTs and CSI1/POM2 function. Hence, two complementary principles underpin wall patterning during xylem vessel development. PMID:28947492

Development of a Dielectric-Loaded Accelerator Test Facility Based on an X-Band Magnicon Amplifier

NASA Astrophysics Data System (ADS)

Gold, S. H.; Kinkead, A. K.; Gai, W.; Power, J. G.; Konecny, R.; Jing, C.; Tantawi, S. G.; Nantista, C. D.; Hu, Y.; Du, X.; Tang, C.; Lin, Y.; Bruce, R. W.; Bruce, R. L.; Fliflet, A. W.; Lewis, D.

2006-01-01

The Naval Research Laboratory (NRL) and Argonne National Laboratory (ANL), in collaboration with the Stanford Linear Accelerator Center (SLAC), are developing a dielectric-loaded accelerator (DLA) test facility powered by the 11.424-GHz magnicon amplifier that was developed jointly by NRL and Omega-P, Inc. Thus far, DLA structures developed by ANL have been tested at the NRL Magnicon Facility without injected electrons, including tests of alumina and magnesium calcium titanate structures at gradients up to ˜8 MV/m. The next step is to inject electrons in order to build a compact DLA test accelerator. The Accelerator Laboratory of Tsinghua University in Beijing, China has developed a 5-MeV electron injector for the accelerator, and SLAC is developing a means to combine the two magnicon output arms, and to drive the injector and an accelerator section with separate control of the power ratio and relative phase. Also, RWBruce Associates, working with NRL, is developing a means to join ceramic tubes to produce long accelerating sections using a microwave brazing process. The installation and commissioning of the first dielectric-loaded test accelerator, including injector, DLA structure, and spectrometer, should take place within the next year.

Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development.

PubMed

Zhang, Lingling; Li, Hanjun; Yu, Jian; Cao, Jingjing; Chen, Huihui; Zhao, Haixia; Zhao, Jianzhi; Yao, Yiyun; Cheng, Huihui; Wang, Lifang; Zhou, Rujiang; Yao, Zhengju; Guo, Xizhi

2014-03-01

Defects of the ventral body wall are prevalent birth anomalies marked by deficiencies in body wall closure, hypoplasia of the abdominal musculature and multiple malformations across a gamut of organs. However, the mechanisms underlying ventral body wall defects remain elusive. Here, we investigated the role of Wnt signaling in ventral body wall development by inactivating Wls or β-catenin in murine abdominal ectoderm. The loss of Wls in the ventral epithelium, which blocks the secretion of Wnt proteins, resulted in dysgenesis of ventral musculature and genito-urinary tract during embryonic development. Molecular analyses revealed that the dermis and myogenic differentiation in the underlying mesenchymal progenitor cells was perturbed by the loss of ectodermal Wls. The activity of the Wnt-Pitx2 axis was impaired in the ventral mesenchyme of the mutant body wall, which partially accounted for the defects in ventral musculature formation. In contrast, epithelial depletion of β-catenin or Wnt5a did not resemble the body wall defects in the ectodermal Wls mutant. These findings indicate that ectodermal Wnt signaling instructs the underlying mesodermal specification and abdominal musculature formation during ventral body wall development, adding evidence to the theory that ectoderm-mesenchyme signaling is a potential unifying mechanism for the origin of ventral body wall defects. Copyright © 2013 Elsevier Inc. All rights reserved.

Illinois Accelerator Research Center

DOE PAGES

Kroc, Thomas K.; Cooper, Charlie A.

2017-10-26

The Illinois Accelerator Research Center (IARC) hosts a new accelerator development program at Fermi National Accelerator Laboratory. IARC provides access to Fermi's state-of-the-art facilities and technologies for research, development and industrialization of particle accelerator technology. In addition to facilitating access to available existing Fermi infrastructure, the IARC Campus has a dedicated 36,000 ft2 heavy assembly building (HAB) with all the infrastructure needed to develop, commission and operate new accelerators. Connected to the HAB is a 47,000 ft Office, Technology and Engineering (OTE) building, paid for by the state, that has office, meeting, and light technical space. The OTE building, whichmore » contains the Accelerator Physics Center, and nearby Accelerator and Technical divisions provide IARC collaborators with unique access to world class expertise in a wide array of accelerator technologies. Finally, at IARC scientists and engineers from Fermilab and academia work side by side with industrial partners to develop breakthroughs in accelerator science and translate them into applications for the nation's health, wealth and security.« less

Illinois Accelerator Research Center

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kroc, Thomas K.; Cooper, Charlie A.

The Illinois Accelerator Research Center (IARC) hosts a new accelerator development program at Fermi National Accelerator Laboratory. IARC provides access to Fermi's state-of-the-art facilities and technologies for research, development and industrialization of particle accelerator technology. In addition to facilitating access to available existing Fermi infrastructure, the IARC Campus has a dedicated 36,000 ft2 heavy assembly building (HAB) with all the infrastructure needed to develop, commission and operate new accelerators. Connected to the HAB is a 47,000 ft Office, Technology and Engineering (OTE) building, paid for by the state, that has office, meeting, and light technical space. The OTE building, whichmore » contains the Accelerator Physics Center, and nearby Accelerator and Technical divisions provide IARC collaborators with unique access to world class expertise in a wide array of accelerator technologies. Finally, at IARC scientists and engineers from Fermilab and academia work side by side with industrial partners to develop breakthroughs in accelerator science and translate them into applications for the nation's health, wealth and security.« less

Illinois Accelerator Research Center

NASA Astrophysics Data System (ADS)

Kroc, Thomas K.; Cooper, Charlie A.

The Illinois Accelerator Research Center (IARC) hosts a new accelerator development program at Fermi National Accelerator Laboratory. IARC provides access to Fermi's state-of-the-art facilities and technologies for research, development and industrialization of particle accelerator technology. In addition to facilitating access to available existing Fermi infrastructure, the IARC Campus has a dedicated 36,000 ft2 Heavy Assembly Building (HAB) with all the infrastructure needed to develop, commission and operate new accelerators. Connected to the HAB is a 47,000 ft2 Office, Technology and Engineering (OTE) building, paid for by the state, that has office, meeting, and light technical space. The OTE building, which contains the Accelerator Physics Center, and nearby Accelerator and Technical divisions provide IARC collaborators with unique access to world class expertise in a wide array of accelerator technologies. At IARC scientists and engineers from Fermilab and academia work side by side with industrial partners to develop breakthroughs in accelerator science and translate them into applications for the nation's health, wealth and security.

Finite element modeling of the cyclic wetting mechanism in the active part of wheat awns.

PubMed

Zickler, Gerald A; Ruffoni, Davide; Dunlop, John W C; Elbaum, Rivka; Weinkamer, Richard; Fratzl, Peter; Antretter, Thomas

2012-12-01

Many plant tissues and organs are capable of moving due to changes in the humidity of the environment, such as the opening of the seed capsule of the ice plant and the opening of the pine cone. These are fascinating examples for the materials engineer, as these tissues are non-living and move solely through the differential swelling of anisotropic tissues and in principle may serve as examples for the bio-inspired design of artificial actuators. In this paper, we model the microstructure of the wild wheat awn (Triticum turgidum ssp. dicoccoides) by finite elements, especially focusing on the specific microscopic features of the active part of the awn. Based on earlier experimental findings, cell walls are modeled as multilayered cylindrical tubes with alternating cellulose fiber orientation in successive layers. It is shown that swelling upon hydration of this system leads to the formation of gaps between the layers, which could act as valves, thus enabling the entry of water into the cell wall. This supports the hypothesis that this plywood-like arrangement of cellulose fibrils enhances the effect of ambient humidity by accelerated water or vapor diffusion along the gaps. The finite element model shows that a certain distribution of axially and tangentially oriented fibers is necessary to generate sufficient tensile stresses within the cell wall to open nanometer-sized gaps between cell wall layers.

Current induced domain wall motion and tilting in Pt/Co/Ta structures with perpendicular magnetic anisotropy in the presence of the Dyzaloshinskii–Moriya interaction

NASA Astrophysics Data System (ADS)

Yun, Jijun; Li, Dong; Cui, Baoshan; Guo, Xiaobin; Wu, Kai; Zhang, Xu; Wang, Yupei; Mao, Jian; Zuo, Yalu; Xi, Li

2018-04-01

Current induced domain wall motion (CIDWM) was studied in Pt/Co/Ta structures with perpendicular magnetic anisotropy and the Dyzaloshinskii–Moriya interaction (DMI) by the spin-orbit torque (SOT). We measured the strength of DMI and SOT efficiency in Pt/Co/Ta with the variation of the thickness of Ta using a current induced hysteresis loop shift method. The results indicate that the DMI stabilizes a chiral Néel-type domain wall (DW), and the DW motion can be driven by the enhanced large SOT generated from Pt and Ta with opposite signs of spin Hall angle in Pt/Co/Ta stacks. The CIDWM velocity, which is 104 times larger than the field driven DW velocity, obeys a creep law, and reaches around tens of meters per second with current density of ~106 A cm‑2. We also found that the Joule heating accompanied with current also accelerates the DW motion. Meanwhile, a domain wall tilting was observed, which increases with current density increasing. These results can be explained by the spin Hall effect generated from both heavy metals Pt and Ta, inherent DMI, and the current accompanying Joule heating effect. Our results could provide some new designing prospects to move multiple DWs by SOT for achieving racetrack memories.

Locally applied leptin induces regional aortic wall degeneration preceding aneurysm formation in apolipoprotein E-deficient mice.

PubMed

Tao, Ming; Yu, Peng; Nguyen, Binh T; Mizrahi, Boaz; Savion, Naphtali; Kolodgie, Frank D; Virmani, Renu; Hao, Shuai; Ozaki, C Keith; Schneiderman, Jacob

2013-02-01

Leptin promotes atherosclerosis and vessel wall remodeling. As abdominal aortic aneurysm (AAA) formation involves tissue remodeling, we hypothesized that local leptin synthesis initiates and promotes this process. Human surgical AAA walls were analyzed for antigen and mRNA levels of leptin and leptin receptor, as well as mRNA for matrix metalloproteinases (MMP)-9 and MMP-12. Leptin and leptin receptor antigen were evident in all AAAs, and leptin, MMP-9, and MMP-12 mRNA was increased relative to age-matched nondilated controls. To simulate in vivo local leptin synthesis, ApoE(-/-) mice were subjected to a paravisceral periaortic application of low-dose leptin. Leptin-treated aortas exhibited decreased transforming growth factor-β and increased MMP-9 mRNA levels 5 days after surgery, and leptin receptor mRNA was upregulated by day 28. Serial ultrasonography demonstrated accelerated regional aortic diameter growth after 28 days, correlating with local medial degeneration, increased MMP-9, MMP-12, and periadventitial macrophage clustering. Furthermore, the combination of local periaortic leptin and systemic angiotensin II administration augmented medial MMP-9 synthesis and aortic aneurysm size. Leptin is locally synthesized in human AAA wall. Paravisceral aortic leptin in ApoE(-/-) mice induces local medial degeneration and augments angiotensin II-induced AAA, thus suggesting novel mechanistic links between leptin and AAA formation.

Locally Applied Leptin Induces Regional Aortic Wall Degeneration Preceding Aneurysm Formation in ApoE Deficient Mice

PubMed Central

Tao, Ming; Yu, Peng; Nguyen, Binh T.; Mizrahi, Boaz; Savion, Naphtali; Kolodgie, Frank D.; Virmani, Renu; Hao, Shuai; Ozaki, C. Keith; Schneiderman, Jacob

2013-01-01

Objective Leptin promotes atherosclerosis and vessel wall remodeling. As abdominal aorta aneurysm (AAA) formation involves tissue remodeling, we hypothesized that local leptin synthesis initiates and promotes this process. Methods and Results Human surgical AAA walls were analyzed for antigen and mRNA levels of leptin and leptin receptor (ObR), as well as mRNA for matrix metalloproteinases (MMP)-9, and MMP-12. Leptin and ObR antigen were evident in all AAAs, and, leptin, MMP-9, and MMP-12 mRNA was increased relative to age-matched non-dilated controls. To simulate in vivo local leptin synthesis, ApoE-/- mice were subjected to a para-visceral peri-aortic application of low-dose leptin. Leptin-treated aortas exhibited decreased TGFβ and increased MMP-9 mRNA levels 5 days after surgery, and ObR mRNA was up-regulated by day 28. Serial ultrasonography demonstrated accelerated regional aortic diameter growth after 28 days, correlating with local medial degeneration, increased MMP-9, MMP-12 and peri-adventitial macrophage clustering. Furthermore, the combination of local peri-aortic leptin and systemic angiotensin II administration augmented medial MMP-9 synthesis and aortic aneurysm size. Conclusions Leptin is locally synthesized in human AAA wall. Para-visceral aortic leptin in ApoE-/- mice induces local medial degeneration, and augments angiotensin II-induced AAA, thus suggesting novel mechanistic links between leptin and AAA formation. PMID:23220275

Quasi-Transient Calculation of Surface Temperatures on a Reusable Booster System with High Angles of Attack

DTIC Science & Technology

2011-12-01

of residuals versus iteration number. “ Intermit ” and “retheta” are turbulence parameters for turbulence intermittency and . 42 ix Figure 4-7 – Wall...is based on the fact that “the flow‐field adapts at a very fast rate to changes in the free stream conditions as the vehicle is accelerating. This...4‐6 – Example of residuals versus iteration number. “ Intermit ” and “retheta” are turbulence parameters for turbulence intermittency and

Longitudinal bunch monitoring at the Fermilab Tevatron and Main Injector synchrotrons

DOE PAGES

Thurman-Keup, R.; Bhat, C.; Blokland, W.; ...

2011-10-17

The measurement of the longitudinal behavior of the accelerated particle beams at Fermilab is crucial to the optimization and control of the beam and the maximizing of the integrated luminosity for the particle physics experiments. Longitudinal measurements in the Tevatron and Main Injector synchrotrons are based on the analysis of signals from resistive wall current monitors. This study describes the signal processing performed by a 2 GHz-bandwidth oscilloscope together with a computer running a LabVIEW program which calculates the longitudinal beam parameters.

Demonstration of a high repetition rate capillary discharge waveguide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gonsalves, A. J., E-mail: ajgonsalves@lbl.gov; Pieronek, C.; Daniels, J.

2016-01-21

A hydrogen-filled capillary discharge waveguide operating at kHz repetition rates is presented for parameters relevant to laser plasma acceleration (LPA). The discharge current pulse was optimized for erosion mitigation with laser guiding experiments and MHD simulation. Heat flow simulations and measurements showed modest temperature rise at the capillary wall due to the average heat load at kHz repetition rates with water-cooled capillaries, which is promising for applications of LPAs such as high average power radiation sources.

An Investigation of Accelerating Mechanisms in a Plasma Focus Relevant to Interrupting Switches.

DTIC Science & Technology

1983-07-01

drift region so as to reduce beam loss due to contact with the conductive walls of the drift tube . The beam guiding apparatus was shown *i to increase...secondary discharge had an adverse effect on the trans- mission of the electron beam through the drift tube . This effect, which was shown to be...the electron beam from entering the drift tube region. .A -4 Io For CiA&- TAR - ’ ’--, U Unclassified SECURITY CLASSIFICATION OF THIS PAGEfhe, 00i Ent

Centrifugal Size-Separation Sieve for Granular Materials

NASA Technical Reports Server (NTRS)

Walton, Otis (Inventor); Dreyer, Christopher (Inventor); Riedel, Edward (Inventor)

2015-01-01

A centrifugal sieve and method utilizes centrifugal force in rapidly-rotated cylindrical or conical screens as the primary body force contributing to size segregation. Within the centrifugal acceleration field, vibration and/or shearing flows are induced to facilitate size segregation and eventual separation of the fines from the coarse material. Inside a rotating cylindrical or conical screen, a separately-rotated screw auger blade can be used to transport material along the rotating cylinder or conical wall and to induce shearing in the material.

Deformation monitoring at Mount St. Helens in 1981 and 1982

USGS Publications Warehouse

Chadwick, W.W.; Swanson, D.A.; Iwatsubo, E.Y.; Heliker, C.C.; Leighley, T.A.

1983-01-01

For several weeks before each eruption of Mount St. Helens in 1981 and 1982, viscous magma rising in the feeder conduit inflated the lava dome and shoved the crater floor laterally against the immobile crater walls, producing ground cracks and thrust faults. The rates of deformation accelerated before eruptions, and thus it was possible to predict eruptions 3 to 19 days in advance. Lack of deformation outside the crater showed that intrusion of magma during 1981 and 1982 was not voluminous.

Local distribution of wall static pressure and heat transfer on a rough flat plate impinged by a slot air jet

NASA Astrophysics Data System (ADS)

Meda, Adimurthy; Katti, Vadiraj V.

2017-08-01

The present work experimentally investigates the local distribution of wall static pressure and the heat transfer coefficient on a rough flat plate impinged by a slot air jet. The experimental parameters include, nozzle-to-plate spacing (Z /D h = 0.5-10.0), axial distance from stagnation point ( x/D h ), size of detached rib ( b = 4-12 mm) and Reynolds number ( Re = 2500-20,000). The wall static pressure on the surface is recorded using a Pitot tube and a differential pressure transmitter. Infrared thermal imaging technique is used to capture the temperature distribution on the target surface. It is observed that, the maximum wall static pressure occurs at the stagnation point ( x/D h = 0) for all nozzle-to-plate spacing ( Z/D h ) and rib dimensions studied. Coefficient of wall static pressure ( C p ) decreases monotonically with x/D h . Sub atmospheric pressure is evident in the detached rib configurations for jet to plate spacing up to 6.0 for all ribs studied. Sub atmospheric region is stronger at Z/D h = 0.5 due to the fluid accelerating under the rib. As nozzle to plate spacing ( Z/D h ) increases, the sub-atmospheric region becomes weak and vanishes gradually. Reasonable enhancement in both C p as well as Nu is observed for the detached rib configuration. Enhancement is found to decrease with the increase in the rib width. The results of the study can be used in optimizing the cooling system design.

Wall shear stress estimation in the aorta: Impact of wall motion, spatiotemporal resolution, and phase noise.

PubMed

Zimmermann, Judith; Demedts, Daniel; Mirzaee, Hanieh; Ewert, Peter; Stern, Heiko; Meierhofer, Christian; Menze, Bjoern; Hennemuth, Anja

2018-04-01

Wall shear stress (WSS) presents an important parameter for assessing blood flow characteristics and evaluating flow-mediated lesions in the aorta. To investigate the robustness of WSS and oscillatory shear index (OSI) estimation based on 4D flow MRI against vessel wall motion, spatiotemporal resolution, and velocity encoding (VENC). Simulated and prospective. Synthetic 4D flow MRI data of the aorta, simulated using the Lattice-Boltzmann method; in vivo 4D flow MRI data of the aorta from healthy volunteers (n = 11) and patients with congenital heart defects (n = 17). 1.5T; 4D flow MRI with PEAK-GRAPPA acceleration and prospective electrocardiogram triggering. Predicated upon 3D cubic B-splines interpolation of the image velocity field, WSS was estimated in mid-systole, early-diastole, and late-diastole and OSI was derived. We assessed the impact of spatiotemporal resolution and phase noise, and compared results based on tracked-using deformable registration-and static vessel wall location. Bland-Altman analysis to assess WSS/OSI differences; Hausdorff distance (HD) to assess wall motion; and Pearson's correlation coefficient (PCC) to assess correlation of HD with WSS. Synthetic data results show systematic over-/underestimation of WSS when different spatial resolution (mean ± 1.96 SD up to -0.24 ± 0.40 N/m 2 and 0.5 ± 1.38 N/m 2 for 8-fold and 27-fold voxel size, respectively) and VENC-depending phase noise (mean ± 1.96 SD up to 0.31 ± 0.12 N/m 2 and 0.94 ± 0.28 N/m 2 for 2-fold and 4-fold VENC increase, respectively) are given. Neglecting wall motion when defining the vessel wall perturbs WSS estimates to a considerable extent (1.96 SD up to 1.21 N/m 2 ) without systematic over-/underestimation (Bland-Altman mean range -0.06 to 0.05). In addition to sufficient spatial resolution and velocity to noise ratio, accurate tracking of the vessel wall is essential for reliable image-based WSS estimation and should not be neglected if wall motion is present. 2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018. © 2018 International Society for Magnetic Resonance in Medicine.

Effect of vortical structures on velocity and turbulent fields in the near region of an impinging turbulent jet

NASA Astrophysics Data System (ADS)

Yadav, Harekrishna; Agrawal, Amit

2018-03-01

This experimental study pertains to the formation of a secondary peak in heat transfer distribution for an axisymmetric turbulent impinging submerged jet. The analysis of instantaneous fields is undertaken at various Reynolds numbers based upon the bulk velocity and nozzle diameter (Re = 1300-10 000) and surface spacings (L/D = 0.25-6). Our analysis shows that flow separation and reattachment correspond to decrease/increase in local pressure and are caused by primary vortices; these are further linked to the location of maxima in streamwise and cross-stream velocities. It is further observed that the locations of maxima and minima in velocities are linked to fluctuations in rms velocities and thickening/thinning of the boundary layer. The vortices transported along the surface either coalesce among themselves or combine with other eddies to form a primary vortex. The primary vortex while getting convected downstream makes multiple interactions with the inner shear layer and causes waviness in instantaneous flow fields. In their later stage, the primary vortex moves away from the wall and accelerates, while the flow decelerates in the inner shear layer. The accelerated fluid in the outer shear layer pulls the downstream fluid from the inner shear layer and leads to the formation of a secondary vortex. After a certain distance downstream, the secondary vortex rolling between the primary vortex and the wall eventually breaks down, while the flow reattaches to the wall. The behavior of time average and instantaneous velocity fields suggests that unsteadiness in the heat transfer is linked to the location of maximum streamwise velocity, location of flow attachment, location of rms velocity, and thickness of the boundary layer. The instantaneous velocity fields show that for a given surface spacing, the chances for the appearance of the secondary vortex reduce with an increase in Reynolds number because of the reduction in space available for the secondary vortex to develop. It is further deduced that the strength of the secondary vortex is primarily dependent upon the strength of the primary vortex. However, the velocity field estimated using the linear stochastic estimation technique shows a tendency for the formation of the secondary vortex at higher Reynolds number, suggesting that most measurements do not resolve them well. Our analysis explains the reason for the appearance of the secondary peak in heat transfer distribution and helps resolve the contradictions in the literature regarding this phenomenon.

Dynamics of an open basaltic magma system: The 2008 activity of the Halema‘uma‘u Overlook vent, Kīlauea Caldera

USGS Publications Warehouse

Eychenne, Julia; Houghton, Bruce F.; Swanson, Don; Carey, Rebecca; Swavely, Lauren

2015-01-01

On March 19, 2008 a small explosive event accompanied the opening of a 35-m-wide vent (Overlook vent) on the southeast wall of Halema‘uma‘u Crater in Kīlauea Caldera, initiating an eruptive period that extends to the time of writing. The peak of activity, in 2008, consisted of alternating background open-system outgassing and spattering punctuated by sudden, short-lived weak explosions, triggered by collapses of the walls of the vent and conduit. Near-daily sampling of the tephra from this open system, along with exceptionally detailed observations, allow us to study the dynamics of the activity during two eruptive sequences in late 2008. Each sequence includes background activity preceding and following one or more explosions in September and October 2008 respectively. Componentry analyses were performed for daily samples to characterise the diversity of the ejecta. Nine categories of pyroclasts were identified in all the samples, including wall-rock fragments. The six categories of juvenile clasts can be grouped in three classes based on vesicularity: (1) poorly, (2) uniformly highly to extremely, and (3) heterogeneously highly vesicular. The wall-rock and juvenile clasts show dissimilar grainsize distributions, reflecting different fragmentation mechanisms. The wall-rock particles formed by failure of the vent and conduit walls above the magma free surface and were then passively entrained in the eruptive plume. The juvenile componentry reveals consistent contrasts in degassing and fragmentation processes before, during and after the explosive events. We infer a crude ‘layering’ developed in the shallow melt, in terms of both rheology and bubble and volatile contents, beneath a convecting free surface during background activity. A tens-of-centimetres thick viscoelastic surface layer was effectively outgassed and relatively cool, while at depths of less than 100 m, the melt remained slightly supersaturated in volatiles and actively vesiculating. Decoupled metre-sized bubbles rising through the column burst through the free surface frequently, ejecting fragments of the outgassed upper layer. When the surface was abruptly perturbed by the rock-falls, existing mm-sized bubbles expanded, leading to the acceleration of adjacent melt upward and consecutive explosions, while renewed nucleation created a minor population of 10-micron-sized bubbles. After each explosive event in September–October 2008, this layering was re-established but with decreasing vigour, suggesting that the magma batch as a whole was becoming progressively depleted in dissolved volatiles.

The Effect of Drive Signal Limiting on High Cycle Fatigue Life Analysis

NASA Technical Reports Server (NTRS)

Kihm, Frederic; Rizzi, Stephen A.

2014-01-01

It is common practice to assume a Gaussian distribution of both the input acceleration and the response when modeling random vibration tests. In the laboratory, however, shaker controllers often limit the drive signal to prevent high amplitude peaks. The high amplitudes may either be truncated at a given level (socalled brick wall limiting or abrupt clipping), or compressed (soft limiting), resulting in drive signals which are no longer Gaussian. The paper first introduces several methods for limiting a drive signal, including brick wall limiting and compression. The limited signal is then passed through a linear time-invariant system representing a device under test. High cycle fatigue life predictions are subsequently made using spectral fatigue and rainflow cycle counting schemes. The life predictions are compared with those obtained from unclipped input signals. Some guidelines are provided to help the test engineer decide how clipping should be applied under different test scenarios.

Ion Voltage Diagnostics in the Far-Field Plume of a High-Specific Impulse Hall Thruster

NASA Technical Reports Server (NTRS)

Hofer, Richard R.; Haas, James M.; Gallimore, Alec D.

2003-01-01

The effects of the magnetic field and discharge voltage on the far-field plume of the NASA 173Mv2 laboratory-model Hall thruster were investigated. A cylindrical Langmuir probe was used to measure the plasma potential and a retarding potential analyzer was employed to measure the ion voltage distribution. The plasma potential was affected by relatively small changes in the external magnetic field, which suggested a means to control the plasma surrounding the thruster. As the discharge voltage increased, the ion voltage distribution showed that the acceleration efficiency increased and the dispersion efficiency decreased. This implied that the ionization zone was growing axially and moving closer to the anode, which could have affected thruster efficiency and lifetime due to higher wall losses. However, wall losses may have been reduced by improved focusing efficiency since the total efficiency increased and the plume divergence decreased with discharge voltage.

Flowing gas, non-nuclear experiments on the gas core reactor

NASA Technical Reports Server (NTRS)

Kunze, J. F.; Suckling, D. H.; Copper, C. G.

1972-01-01

Flow tests were conducted on models of the gas core (cavity) reactor. Variations in cavity wall and injection configurations were aimed at establishing flow patterns that give a maximum of the nuclear criticality eigenvalue. Correlation with the nuclear effect was made using multigroup diffusion theory normalized by previous benchmark critical experiments. Air was used to simulate the hydrogen propellant in the flow tests, and smoked air, argon, or freon to simulate the central nuclear fuel gas. All tests were run in the down-firing direction so that gravitational effects simulated the acceleration effect of a rocket. Results show that acceptable flow patterns with high volume fraction for the simulated nuclear fuel gas and high flow rate ratios of propellant to fuel can be obtained. Using a point injector for the fuel, good flow patterns are obtained by directing the outer gas at high velocity along the cavity wall, using louvered or oblique-angle-honeycomb injection schemes.

Intraspecific scaling of arterial blood pressure in the Burmese python.

PubMed

Enok, Sanne; Slay, Christopher; Abe, Augusto S; Hicks, James W; Wang, Tobias

2014-07-01

Interspecific allometric analyses indicate that mean arterial blood pressure (MAP) increases with body mass of snakes and mammals. In snakes, MAP increases in proportion to the increased distance between the heart and the head, when the heart-head vertical distance is expressed as ρgh (where ρ is the density of blood, G: is acceleration due to gravity and h is the vertical distance above the heart), and the rise in MAP is associated with a larger heart to normalize wall stress in the ventricular wall. Based on measurements of MAP in Burmese pythons ranging from 0.9 to 3.7 m in length (0.20-27 kg), we demonstrate that although MAP increases with body mass, the rise in MAP is merely half of that predicted by heart-head distance. Scaling relationships within individual species, therefore, may not be accurately predicted by existing interspecific analyses. © 2014. Published by The Company of Biologists Ltd.

Fracture modes in human teeth.

PubMed

Lee, J J-W; Kwon, J-Y; Chai, H; Lucas, P W; Thompson, V P; Lawn, B R

2009-03-01

The structural integrity of teeth under stress is vital to functional longevity. We tested the hypothesis that this integrity is limited by fracture of the enamel. Experiments were conducted on molar teeth, with a metal rod loaded onto individual cusps. Fracture during testing was tracked with a video camera. Two longitudinal modes of cracking were observed: median cracking from the contact zone, and margin cracking along side walls. Median cracks initiated from plastic damage at the contact site, at first growing slowly and then accelerating to the tooth margin. Margin cracks appeared to originate from the cemento-enamel junction, and traversed the tooth wall adjacent to the loaded cusp from the gingival to the occlusal surface. All cracks remained confined within the enamel shell up to about 550 N. At higher loads, additional crack modes--such as enamel chipping and delamination--began to manifest themselves, leading to more comprehensive failure of the tooth structure.

Extension of the momentum transfer model to time-dependent pipe turbulence.

PubMed

Calzetta, Esteban

2012-02-01

We analyze a possible extension of Gioia and Chakraborty's momentum transfer model of friction in steady turbulent pipe flows [Phys. Rev. Lett. 96, 044502 (2006)] to the case of time- and/or space-dependent turbulent flows. The end result is an expression for the stress at the wall as the sum of a steady and a dynamic component. The steady part is obtained by using the instantaneous velocity in the expression for the stress at the wall of a stationary flow. The unsteady part is a weighted average over the history of the flow acceleration, with a weighting function similar to that proposed by Vardy and Brown [J. Sound Vibr. 259, 1011 (2003); J. Sound Vibr. 270, 233 (2004)], but naturally including the effect of spatial derivatives of the mean flow, as in the Brunone model [Brunone et al., J. Water Res. Plan. Manage. 126, 236 (2000)].

Fabrication of aligned porous LaNi0.6Fe0.4O3 perovskite by water based freeze casting

NASA Astrophysics Data System (ADS)

Soltani, Niloofar; Martínez-Bautista, Rubén; Bahrami, Amin; Huerta Arcos, Lázaro; Cassir, Michel; Chávez Carvayar, José

2018-05-01

A novel porous cathode of LaNi0.6Fe0.4O3 perovskite with aligned porosities was engineered for solid oxide fuel cells. LaNi0.6Fe0.4O3 was produced through metal nitrate and acid citric combustion method and calcined at different temperatures. The synthesized LNF at 600 °C shows specific surface area (SBET) of 24.4 m2 g-1 and an average pore size of 12.2 nm. The chemical composition and structure of LaNi0.6Fe0.4O3 synthesized at temperature 600-1400 °C, were analyzed by XRD, XPS and HRTEM. SEM observations of freeze cast nano-sized LNF showed the vertically aligned hexagonal walls. These walls contain a great value of fine pores which accelerate the gas transportation.

Generation and confinement of microwave gas-plasma in photonic dielectric microstructure.

PubMed

Debord, B; Jamier, R; Gérôme, F; Leroy, O; Boisse-Laporte, C; Leprince, P; Alves, L L; Benabid, F

2013-10-21

We report on a self-guided microwave surface-wave induced generation of ~60 μm diameter and 6 cm-long column of argon-plasma confined in the core of a hollow-core photonic crystal fiber. At gas pressure of 1 mbar, the micro-confined plasma exhibits a stable transverse profile with a maximum gas-temperature as high as 1300 ± 200 K, and a wall-temperature as low as 500 K, and an electron density level of 10¹⁴ cm⁻³. The fiber guided fluorescence emission presents strong Ar⁺ spectral lines in the visible and near UV. Theory shows that the observed combination of relatively low wall-temperature and high ionisation rate in this strongly confined configuration is due to an unprecedentedly wide electrostatic space-charge field and the subsequent ion acceleration dominance in the plasma-to-gas power transfer.

Experiments in Transitional Boundary Layers With Emphasis on High Free-Stream Disturbance Level, Surface Concave Curvature and Strong Favorable Streamwise Pressure Gradient Effects

NASA Technical Reports Server (NTRS)

Simon, T. W.; Volino, R. J.

2007-01-01

Experiments on boundary layer transition with flat, concave and convex walls and various levels of free-stream disturbance and with zero and strong streamwise acceleration have been conducted. Measurements of both fluid mechanics and heat transfer processes were taken. Examples are profiles of mean velocity and temperature; Reynolds normal and shear stresses; turbulent streamwise and cross-stream heat fluxed; turbulent Prandtl number; and streamwise variations of wall skin friction and heat transfer coefficient values. Free-stream turbulence levels were varied over the range from about 0.3 percent to about 8 percent. The effects of curvature on the onset of transition under low disturbance conditions are clear; concave curvature leads to an earlier and more rapid transition and the opposite is true for convex curvature This was previously known but little documentation of the transport processes in the flow was available

Improved Conjugate Gradient Bundle Adjustment of Dunhuang Wall Painting Images

NASA Astrophysics Data System (ADS)

Hu, K.; Huang, X.; You, H.

2017-09-01

Bundle adjustment with additional parameters is identified as a critical step for precise orthoimage generation and 3D reconstruction of Dunhuang wall paintings. Due to the introduction of self-calibration parameters and quasi-planar constraints, the structure of coefficient matrix of the reduced normal equation is banded-bordered, making the solving process of bundle adjustment complex. In this paper, Conjugate Gradient Bundle Adjustment (CGBA) method is deduced by calculus of variations. A preconditioning method based on improved incomplete Cholesky factorization is adopt to reduce the condition number of coefficient matrix, as well as to accelerate the iteration rate of CGBA. Both theoretical analysis and experimental results comparison with conventional method indicate that, the proposed method can effectively conquer the ill-conditioned problem of normal equation and improve the calculation efficiency of bundle adjustment with additional parameters considerably, while maintaining the actual accuracy.

Hypoxia-responsive ERFs involved in postdeastringency softening of persimmon fruit.

PubMed

Wang, Miao-Miao; Zhu, Qing-Gang; Deng, Chu-Li; Luo, Zheng-Rong; Sun, Ning-Jing; Grierson, Donald; Yin, Xue-Ren; Chen, Kun-Song

2017-11-01

Removal of astringency by endogenously formed acetaldehyde, achieved by postharvest anaerobic treatment, is of critical importance for many types of persimmon fruit. Although an anaerobic environment accelerates de-astringency, it also has the deleterious effect of promoting excessive softening, reducing shelf life and marketability. Some hypoxia-responsive ethylene response factors (ERFs) participate in anaerobic de-astringency, but their role in accelerated softening was unclear. Undesirable rapid softening induced by high CO 2 (95%) was ameliorated by adding the ethylene inhibitor 1-MCP (1 μL/L), resulting in reduced astringency while maintaining firmness, suggesting that CO 2 -induced softening involves ethylene signalling. Among the hypoxia-responsive genes, expression of eight involved in fruit cell wall metabolism (Dkβ-gal1/4, DkEGase1, DkPE1/2, DkPG1, DkXTH9/10) and three ethylene response factor genes (DkERF8/16/19) showed significant correlations with postdeastringency fruit softening. Dual-luciferase assay indicated that DkERF8/16/19 could trans-activate the DkXTH9 promoter and this interaction was abolished by a mutation introduced into the C-repeat/dehydration-responsive element of the DkXTH9 promoter, supporting the conclusion that these DkERFs bind directly to the DkXTH9 promoter and regulate this gene, which encodes an important cell wall metabolism enzyme. Some hypoxia-responsive ERF genes are involved in deastringency and softening, and this linkage was uncoupled by 1-MCP. Fruit of the Japanese cultivar 'Tonewase' provide a model for altered anaerobic response, as they lost astringency yet maintained firmness after CO 2 treatment without 1-MCP and changes in cell wall enzymes and ERFs did not occur. © 2017 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

Facility for Heavy Ion Collision Experiment at RAON

NASA Astrophysics Data System (ADS)

Kim, Young Jin; Kim, Do Gyun; Kim, Gi Dong; Kim, Yong Hak; Kim, Young-Jin; Kim, Yong Kyun; Kwon, Young Kwan; Yun, Chong Cheol; Hong, Byungsik; Sei Lee, Kyung; Kim, Eun Joo; Ahn, Jung Keun; Lee, Hyo Sang

2014-03-01

The Rare Isotope Science Project (RISP) was established in December 2011 in order to carry out the technical design and the establishment of the accelerator complex (RAON) for the rare isotope science in Korea. The rare isotope accelerator at RAON will provide both stable and rare isotope heavy-ion beams the energy range from a few MeV/nucleon to a few hundreds of MeV/nucleon for researches in fields of basic and applied science. Large Acceptance Multipurpose Spectrometer (LAMPS) at RAON is a heavy-ion collision experimental facility for studying nuclear symmetry energy by using rare isotope beams. Two different experimental setups of LAMPS are designed for covering entire energy range at RAON. One is for low energy (< 18.5 MeV/nucleon) heavy-ion collision experiment for day-1 experiments. This experimental setup consists of an array of ΔE-E Si-CsI detectors, a gamma array to cover backward polar angle, and a forward neutron wall. The other is for completing an event reconstruction by detecting all the particles produced in high energy heavy-ion collisions within a large acceptance angle to measure particle spectrum, yield, ratio and collective flow of pions, protons, neutrons, and intermediate fragments at the same time. The experimental setup consists of a superconducting spectrometer, a dipole spectrometer, and a forward neutron wall. A Time Projection Chamber (TPC) will be placed inside of superconducting solenoid magnet of 0.6 T for charged particle tracking. The dipole spectrometer will be located forward of the superconducting spectrometer and it will be composed of a combination of quadrupole, dipole magnets, focal plane detector, tracking stations, and Time-of-Flight (ToF) detector at the end. The neutron wall will be made of 10 layers of plastic scintillators for neutron tracking. In this presentation, the detail physics and design of LAMPS at RAON will be discussed.

Logs of Paleoseismic Excavations Across the Central Range Fault, Trinidad

USGS Publications Warehouse

Crosby, Christopher J.; Prentice, Carol S.; Weber, John; Ragona, Daniel

2009-01-01

This publication makes available maps and trench logs associated with studies of the Central Range Fault, part of the South American-Caribbean plate boundary in Trinidad. Our studies were conducted in 2001 and 2002. We mapped geomorphic features indicative of active faulting along the right-lateral, Central Range Fault, part of the South American-Caribbean plate boundary in Trinidad. We excavated trenches at two sites, the Samlalsingh and Tabaquite sites. At the Samlalsingh site, sediments deposited after the most recent fault movement bury the fault, and the exact location of the fault was unknown until we exposed it in our excavations. At this site, we excavated a total of eleven trenches, six of which exposed the fault. The trenches exposed fluvial sediments deposited over a strath terrace developed on Miocene bedrock units. We cleaned the walls of the excavations, gridded the walls with either 1 m X 1 m or 1 m X 0.5 m nail and string grid, and logged the walls in detail at a scale of 1:20. Additionally, we described the different sedimentary units in the field, incorporating these descriptions into our trench logs. We mapped the locations of the trenches using a tape and compass. Our field logs were scanned, and unit contacts were traced in Adobe Illustrator. The final drafted logs of all the trenches are presented here, along with photographs showing important relations among faults and Holocene sedimentary deposits. Logs of south walls were reversed in Illustrator, so that all logs are drafted with the view direction to the north. We collected samples of various materials exposed in the trench walls, including charcoal samples for radiocarbon dating from both faulted and unfaulted deposits. The locations of all samples collected are shown on the logs. The ages of seventeen of the charcoal samples submitted for radiocarbon analysis at the University of Arizona Accelerator Mass Spectrometry Laboratory in Tucson, Ariz., are given in Table 1. Samples found in Table 1 are shown in red on the trench logs. All radiocarbon ages are calibrated and given with 2 standard deviation age ranges. Our studies suggest that the Central Range Fault is a Holocene fault capable of producing damaging earthquakes in Trinidad

Near Stall Flow Analysis in the Transonic Fan of the RTA Propulsion System

NASA Technical Reports Server (NTRS)

Hah, Chunill

2010-01-01

Turbine-based propulsion systems for access to space have been investigated at NASA Glenn Research center. A ground demonstrator engine for validation testing has been developed as a part of the program. The demonstrator, the Revolutionary Turbine Accelerator (RTA-1), is a variable cycle turbofan ramjet designed to transition from an augmented turbofan to a ramjet that produces the thrust required to accelerate the vehicle to Mach 4. The RTA-1 is designed to accommodate a large variation in bypass ratio from sea level static to Mach 4 flight condition. A key component of this engine is a new fan stage that accommodates these large variations in bypass ratio and flow ranges. In the present study, unsteady flow behavior in the fan of the RTA-1 is studied in detail with large eddy simulation (LES) and the numerical results are compared with measured data. During the experimental study of the fan stage, humming sound was detected at 100 % speed near stall operation. The main purpose of the study is to investigate details of the unsteady flow behavior at near stall operation and to identify a possible cause of the hum. The large eddy simulation of the current flow field reproduces main features of the measured flow very well. The LES simulation indicates that non-synchronous flow instability develops as the fan operates toward the stall limit. The FFT analysis of the calculated wall pressure shows that the rotating flow instability has the characteristic frequency that is about 50% of the blade passing frequency.

Decreased expression of γ-carboxylase in diabetes-associated arterial stiffness: impact on matrix Gla protein.

PubMed

Doyon, Marielle; Mathieu, Patrick; Moreau, Pierre

2013-02-01

Arterial stiffness is accelerated in type 1 diabetic patients. Medial artery calcification (MAC) contributes to the development of arterial stiffness. Vitamin K oxidoreductase (VKOR) reduces the vitamin K required by γ-carboxylase to activate matrix γ-carboxyglutamic acid (Gla) protein (MGP), an inhibitor of vascular calcification. This study aimed to evaluate the hypothesis that diabetes reduces the γ-carboxylation of MGP in the aortic wall, leading to increased vascular calcification, and the role of γ-carboxylase and VKOR in this γ-carboxylation deficit. Type 1 diabetes was induced in male Wistar rats with a single ip injection of streptozotocin. Augmentation of arterial stiffness in diabetic rats was shown by a 44% increase in aortic pulse wave velocity. Aortic and femoral calcification were increased by 26 and 56%, respectively. γ-Carboxylated MGP (cMGP, active) was reduced by 36% and the aortic expression of γ-carboxylase was reduced by 58%. Expression of γ-carboxylase correlated with cMGP (r= 0.59) and aortic calcification (r = -0.57). VKOR aortic expression and activity were not modified by diabetes. Vitamin K plasma concentrations were increased by 191% in diabetic rats. In ex vivo experiments with aortic rings, vitamin K supplementation prevented the glucose-induced decrease in γ-carboxylase expression. Our results suggest that reduced cMGP, through an impaired expression of γ-carboxylase, is involved in the early development of MAC in diabetes, and therefore, in the acceleration of arterial stiffness. A defect in vitamin K uptake by target cells could also be involved.

Extended Plate and Beam Wall System: Concept Investigation and Initial Evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiehagen, J.; Kochkin, V.

A new and innovative High-R wall design, referred to as the Extended Plate & Beam (EP&B), is under development. The EP&B system uniquely integrates foam sheathing insulation with wall framing such that wood structural panels are installed exterior of the foam sheathing, enabling the use of standard practices for installation of drainage plane, windows and doors, claddings, cavity insulation, and the standard exterior foam sheathing installation approach prone to damage of the foam during transportation of prefabricated wall panels. As part of the ongoing work, the EP&B wall system concept has undergone structural verification testing and has been positively vettedmore » by a group of industry stakeholders. Having passed these initial milestone markers, the advanced wall system design has been analyzed to assess cost implications relative to other advanced wall systems, undergone design assessment to develop construction details, and has been evaluated to develop representative prescriptive requirements for the building code. This report summarizes the assessment steps conducted to-date and provides details of the concept development.« less

Extended Plate and Beam Wall System: Concept Investigation and Initial Evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiehagen, J.; Kochkin, V.

2015-08-01

A new and innovative High-R wall design, referred to as the Extended Plate & Beam (EP&B), is under development. The EP&B system uniquely integrates foam sheathing insulation with wall framing such that wood structural panels are installed exterior of the foam sheathing, enabling the use of standard practices for installation of drainage plane, windows and doors, claddings, cavity insulation, and the standard exterior foam sheathing installation approach prone to damage of the foam during transportation of prefabricated wall panels. As part of the ongoing work, the EP&B wall system concept has undergone structural verification testing and has been positively vettedmore » by a group of industry stakeholders. Having passed these initial milestone markers, the advanced wall system design has been analyzed to assess cost implications relative to other advanced wall systems, undergone design assessment to develop construction details, and has been evaluated to develop representative prescriptive requirements for the building code. This report summarizes the assessment steps conducted to-date and provides details of the concept development.« less

Wall-to-wall Landsat TM classifications for Georgia in support of SAFIS using FIA plots for training and verification

Treesearch

William H. Cooke; Andrew J. Hartsell

2000-01-01

Wall-to-wall Landsat TM classification efforts in Georgia require field validation. Validation uslng FIA data was testing by developing a new crown modeling procedure. A methodology is under development at the Southern Research Station to model crown diameter using Forest Health monitoring data. These models are used to simulate the proportion of tree crowns that...