Sample records for wall motion scoring

  1. Assessment of LVEF using a new 16-segment wall motion score in echocardiography.

    PubMed

    Lebeau, Real; Serri, Karim; Lorenzo, Maria Di; Sauvé, Claude; Le, Van Hoai Viet; Soulières, Vicky; El-Rayes, Malak; Pagé, Maude; Zaïani, Chimène; Garot, Jérôme; Poulin, Frédéric

    2018-06-01

    Simpson biplane method and 3D by transthoracic echocardiography (TTE), radionuclide angiography (RNA) and cardiac magnetic resonance imaging (CMR) are the most accepted techniques for left ventricular ejection fraction (LVEF) assessment. Wall motion score index (WMSI) by TTE is an accepted complement. However, the conversion from WMSI to LVEF is obtained through a regression equation, which may limit its use. In this retrospective study, we aimed to validate a new method to derive LVEF from the wall motion score in 95 patients. The new score consisted of attributing a segmental EF to each LV segment based on the wall motion score and averaging all 16 segmental EF into a global LVEF. This segmental EF score was calculated on TTE in 95 patients, and RNA was used as the reference LVEF method. LVEF using the new segmental EF 15-40-65 score on TTE was compared to the reference methods using linear regression and Bland-Altman analyses. The median LVEF was 45% (interquartile range 32-53%; range from 15 to 65%). Our new segmental EF 15-40-65 score derived on TTE correlated strongly with RNA-LVEF ( r  = 0.97). Overall, the new score resulted in good agreement of LVEF compared to RNA (mean bias 0.61%). The standard deviations (s.d.s) of the distributions of inter-method difference for the comparison of the new score with RNA were 6.2%, indicating good precision. LVEF assessment using segmental EF derived from the wall motion score applied to each of the 16 LV segments has excellent correlation and agreement with a reference method. © 2018 The authors.

  2. Design and characterisation of a wall motion phantom.

    PubMed

    Dineley, J; Meagher, S; Poepping, T L; McDicken, W N; Hoskins, P R

    2006-09-01

    Arterial wall motion is an essential feature of a healthy cardiovascular system and it is known that wall motion is affected by age and disease. In recent years, methods have been developed for measurement of wall motion with the intention of providing diagnostically useful information. An issue with all of these techniques is the accuracy and variability of both wall motion and derived quantities such as elasticity, which requires the development of suitable test tools. In this paper, a vessel wall phantom is described for use in ultrasound studies of wall motion. The vessel was made from polyvinyl alcohol (PVA) subjected to a freeze-thaw process to form a cryogel (PVA-C). The elastic modulus, acoustic velocity and attenuation coefficient varied from 57 kPa, 1543 m s(-1) and 0.18 dB cm(-1) MHz(-1) for one freeze-thaw cycle to 330 kPa, 1583 m s(-1) and 0.42 dB cm(-1) MHz(-1) for 10 freeze-thaw cycles. Wall motion was effected by the use of pulsatile flow produced from a gear pump. The use of a downstream flow resistor removed gross distortions in the wall motion waveform, possibly by removal of reflected pressure waves. However, a low amplitude 20 Hz oscillation remained, which is unphysiologic and thought to be caused by the vibration of the distended PVA-C vessel.

  3. Regional cardiac wall motion from gated myocardial perfusion SPECT studies

    NASA Astrophysics Data System (ADS)

    Smith, M. F.; Brigger, P.; Ferrand, S. K.; Dilsizian, V.; Bacharach, S. L.

    1999-06-01

    A method for estimating regional epicardial and endocardial wall motion from gated myocardial perfusion SPECT studies has been developed. The method uses epicardial and endocardial boundaries determined from four long-axis slices at each gate of the cardiac cycle. The epicardial and endocardial wall position at each time gate is computed with respect to stationary reference ellipsoids, and wall motion is measured along lines normal to these ellipsoids. An initial quantitative evaluation of the method was made using the beating heart from the dynamic mathematical cardiac torso (MCAT) phantom, with and without a 1.5-cm FWHM Gaussian blurring filter. Epicardial wall motion was generally well-estimated within a fraction of a 3.56-mm voxel, although apical motion was overestimated with the Gaussian filter. Endocardial wall motion was underestimated by about two voxels with and without the Gaussian filter. The MCAT heart phantom was modified to model hypokinetic and dyskinetic wall motion. The wall motion analysis method enabled this abnormal motion to be differentiated from normal motion. Regional cardiac wall motion also was analyzed for /sup 201/Tl patient studies. Estimated wall motion was consistent with a nuclear medicine physician's visual assessment of motion from gated long-axis slices for male and female study examples. Additional research is required for a comprehensive evaluation of the applicability of the method to patient studies with normal and abnormal wall motion.

  4. Clustering Of Left Ventricular Wall Motion Patterns

    NASA Astrophysics Data System (ADS)

    Bjelogrlic, Z.; Jakopin, J.; Gyergyek, L.

    1982-11-01

    A method for detection of wall regions with similar motion was presented. A model based on local direction information was used to measure the left ventricular wall motion from cineangiographic sequence. Three time functions were used to define segmental motion patterns: distance of a ventricular contour segment from the mean contour, the velocity of a segment and its acceleration. Motion patterns were clustered by the UPGMA algorithm and by an algorithm based on K-nearest neighboor classification rule.

  5. Metabolic Syndrome is Associated With Higher Wall Motion Score and Larger Infarct Size After Acute Myocardial Infarction

    PubMed Central

    Hajsadeghi, Shokoufeh; Chitsazan, Mitra; Chitsazan, Mandana; Haghjoo, Majid; Babaali, Nima; Norouzzadeh, Zahra; Mohsenian, Maryam

    2015-01-01

    Background: Infarct size is an important surrogate end point for early and late mortality after acute myocardial infarction. Despite the high prevalence of metabolic syndrome in patients with atherosclerotic diseases, adequate data are still lacking regarding the extent of myocardial necrosis after acute myocardial infarction in these patients. Objectives: In the present study we aimed to compare myocardial infarction size in patients with metabolic syndrome to those without metabolic syndrome using peak CK-MB and cardiac troponin I (cTnI) at 72 hours after the onset of symptoms. Patients and Methods: One-hundred patients with metabolic syndrome (group I) and 100 control subjects without metabolic syndrome (group II) who experienced acute myocardial infarction were included in the study. Diagnosis of metabolic syndrome was based on the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) guidelines published in 2001. Myocardial infarction size was compared between the two groups of patients using peak CK-MB and cTnI level in 72 hours after the onset of symptoms. Results: Peak CK-MB and cTnI in 72 hours were found to be significantly higher in patients with metabolic syndrome compared with control subjects (both P < 0.001). Patients with metabolic syndrome also had markedly higher wall motion abnormality at 72 hours after the onset of symptoms as assessed by echocardiographically-derived Wall Motion Score Index (WMSI) (P < 0.001). Moreover, statistically significant relationships were found between WMSI and peak CK-MB and also cTnI at 72 hours (Spearman's rho = 0.56, P < 0.001 and Spearman's rho = 0.5, P < 0.001; respectively). However, association between WMSI and left ventricular ejection fraction was insignificant (Spearman's rho = -0.05, P = 0.46). Conclusions: We showed that patients with metabolic syndrome have larger infarct size compared to control subjects. PMID:25789257

  6. Theory of Current-Driven Domain Wall Motion

    NASA Astrophysics Data System (ADS)

    Tatara, Gen

    2004-03-01

    Current-induced motion of a domain wall is studied starting from a microscopic Hamiltonian with an exchange interaction between conduction electrons and spins of the wall [1]. With a key observation that the position X and the angle φ0 the wall magnetization forms with the easy plane are the proper collective coordinates to describe its dynamics, it follows straightforwardly that the electric current affects the wall motion in two different ways, in agreement with Berger's pioneering observations[2]. The first is as a force, or momentum transfer, due to the reflection of conduction electrons. This force is proportional to the charge current j and wall resistivity ρ_w, and hence becomes important in thin walls. The other is as a spin torque or spin transfer[3], which is dominant for thick walls where the spin of conduction electron follows the magnetization adiabatically. The motion of a domain wall under a steady current is studied in two limiting cases. In the adiabatic case, we show that even without a pinning force, there is a threshold spin current, j_s^cr∝ K_⊥λ, below which the wall does not move (K_⊥ and λ being the hard-axis magnetic anisotropy and wall thickness, respectively). Below the threshold, the transferred angular momentum is used to shift φ0 and not to the wall motion. The pinning potential V0 affects j_s^cr only if it is very strong, V0 > K_⊥/α, where α is the damping parameter in the Landau-Lifshits-Gilbert equation. Therefore, the critical current for the adiabatic wall does not suffer very much from weak pinning, which is consistent with experimental observations[4]. The wall velocity after depinning is found to be ∝[(j_s/j_s^cr)^2-1]^1/2. In the case of thin wall, driven by a force ∝ ρw j, the critical current density is given by j^cr∝ V_0/ρ_w. In nanocontacts, this is estimated to be ˜ 10^7[A/m^2]. This small critical current would be advantageous for device application. [1] G.Tatara and H.Kohno, cond-mat/0308464

  7. Intraventricular flow alterations due to dyssynchronous wall motion

    NASA Astrophysics Data System (ADS)

    Pope, Audrey M.; Lai, Hong Kuan; Samaee, Milad; Santhanakrishnan, Arvind

    2015-11-01

    Roughly 30% of patients with systolic heart failure suffer from left ventricular dyssynchrony (LVD), in which mechanical discoordination of the ventricle walls leads to poor hemodynamics and suboptimal cardiac function. There is currently no clear mechanistic understanding of how abnormalities in septal-lateral (SL) wall motion affects left ventricle (LV) function, which is needed to improve the treatment of LVD using cardiac resynchronization therapy. We use an experimental flow phantom with an LV physical model to study mechanistic effects of SL wall motion delay on LV function. To simulate mechanical LVD, two rigid shafts were coupled to two segments (apical and mid sections) along the septal wall of the LV model. Flow through the LV model was driven using a piston pump, and stepper motors coupled to the above shafts were used to locally perturb the septal wall segments relative to the pump motion. 2D PIV was used to examine the intraventricular flow through the LV physical model. Alterations to SL delay results in a reduction in the kinetic energy (KE) of the flow field compared to synchronous SL motion. The effect of varying SL motion delay from 0% (synchronous) to 100% (out-of-phase) on KE and viscous dissipation will be presented. This research was supported by the Oklahoma Center for Advancement of Science and Technology (HR14-022).

  8. Temporal analysis of regional wall motion from cine cardiac MRI

    NASA Astrophysics Data System (ADS)

    Ratib, Osman M.; Didier, Dominique; Chretien, Anne; Rosset, Antoine; Magnin, Isabelle E.; Ligier, Yves

    1996-04-01

    The purpose of this work is to develop and to evaluate an automatic analysis technique for quantitative assessment of cardiac function from cine MRI and to identify regional alterations in synchronicity based on Fourier analysis of ventricular wall motion (WM). A temporal analysis technique of left ventricular wall displacement was developed for quantitative analysis of temporal delays in wall motion and applied to gated cine 'dark blood' cardiac MRI. This imaging technique allows the user to saturate the blood both above and below the imaging slice simultaneously by using a specially designed rf presaturation pulse. The acquisition parameters are: TR equals 25 - 60 msec, TE equals 5 - 7 msec, 0 equals 25 degrees, slice thickness equals 10 mm, 16 to 32 frames/cycle. Automatic edge detection was used to outline the ventricular cavities on all frames of a cardiac cycle. Two different segmentation techniques were applied to all studies and lead to similar results. Further improvement in edge detection accuracy was achieved by temporal interpolation of individual contours on each image of the cardiac cycle. Radial analysis of the ventricular wall motion was then performed along 64 radii drawn from the center of the ventricular cavity. The first harmonic of the Fourier transform of each radial motion curve is calculated. The phase of the fundamental Fourier component is used as an index of synchrony (delay) of regional wall motion. Results are displayed in color-coded maps of regional alterations in the amplitude and synchrony of wall motion. The temporal delays measured from individual segments are evaluated through a histogram of phase distribution, where the width of the main peak is used as an index of overall synchrony of wall motion. The variability of this technique was validated in 10 normal volunteers and was used to identify regions with asynchronous WM in 15 patients with documented CAD. The standard deviation (SD) of phase distribution measured in short axis

  9. Magnetization reversal in ferromagnetic spirals via domain wall motion

    NASA Astrophysics Data System (ADS)

    Schumm, Ryan D.; Kunz, Andrew

    2016-11-01

    Domain wall dynamics have been investigated in a variety of ferromagnetic nanostructures for potential applications in logic, sensing, and recording. We present a combination of analytic and simulated results describing the reliable field driven motion of a domain wall through the arms of a ferromagnetic spiral nanowire. The spiral geometry is capable of taking advantage of the benefits of both straight and circular wires. Measurements of the in-plane components of the spirals' magnetization can be used to determine the angular location of the domain wall, impacting the magnetoresistive applications dependent on the domain wall location. The spirals' magnetization components are found to depend on the spiral parameters: the initial radius and spacing between spiral arms, along with the domain wall location. The magnetization is independent of the parameters of the rotating field used to move the domain wall, and therefore the model is valid for current induced domain wall motion as well. The speed of the domain wall is found to depend on the frequency of the rotating driving field, and the domain wall speeds can be reliably varied over several orders of magnitude. We further demonstrate a technique capable of injecting multiple domain walls and show the reliable and unidirectional motion of domain walls through the arms of the spiral.

  10. Spin-wave-driven high-speed domain-wall motions in soft magnetic nanotubes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Jaehak; Yoo, Myoung-Woo; Kim, Sang-Koog, E-mail: sangkoog@snu.ac.kr

    We report on a micromagnetic simulation study of interactions between propagating spin waves and a head-to-head domain wall in geometrically confined magnetic nanotubes. We found that incident spin waves of specific frequencies can lead to sufficiently high-speed (on the order of a few hundreds of m/s or higher) domain-wall motions in the same direction as that of the incident spin-waves. The domain-wall motions and their speed vary remarkably with the frequency and the amplitude of the incident spin-waves. High-speed domain-wall motions originate from the transfer torque of spin waves' linear momentum to the domain wall, through the partial or completemore » reflection of the incident spin waves from the domain wall. This work provides a fundamental understanding of the interaction of the spin waves with a domain wall in the magnetic nanotubes as well as a route to all-magnetic control of domain-wall motions in the magnetic nanoelements.« less

  11. Brownian motion and entropic torque driven motion of domain walls in antiferromagnets

    NASA Astrophysics Data System (ADS)

    Yan, Zhengren; Chen, Zhiyuan; Qin, Minghui; Lu, Xubing; Gao, Xingsen; Liu, Junming

    2018-02-01

    We study the spin dynamics in antiferromagnetic nanowire under an applied temperature gradient using micromagnetic simulations on a classical spin model with a uniaxial anisotropy. The entropic torque driven domain-wall motion and the Brownian motion are discussed in detail, and their competition determines the antiferromagnetic wall motion towards the hotter or colder region. Furthermore, the spin dynamics in an antiferromagnet can be well tuned by the anisotropy and the temperature gradient. Thus, this paper not only strengthens the main conclusions obtained in earlier works [Kim et al., Phys. Rev. B 92, 020402(R) (2015), 10.1103/PhysRevB.92.020402; Selzer et al., Phys. Rev. Lett. 117, 107201 (2016), 10.1103/PhysRevLett.117.107201], but more importantly gives the concrete conditions under which these conclusions apply, respectively. Our results may provide useful information on the antiferromagnetic spintronics for future experiments and storage device design.

  12. Micromagnetic analysis of current-induced domain wall motion in a bilayer nanowire with synthetic antiferromagnetic coupling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Komine, Takashi, E-mail: komine@mx.ibaraki.ac.jp; Aono, Tomosuke

    We demonstrate current-induced domain wall motion in bilayer nanowire with synthetic antiferromagnetic (SAF) coupling by modeling two body problems for motion equations of domain wall. The influence of interlayer exchange coupling and magnetostatic interactions on current-induced domain wall motion in SAF nanowires was also investigated. By assuming the rigid wall model for translational motion, the interlayer exchange coupling and the magnetostatic interaction between walls and domains in SAF nanowires enhances domain wall speed without any spin-orbit-torque. The enhancement of domain wall speed was discussed by energy distribution as a function of wall angle configuration in bilayer nanowires.

  13. Linear motion feed through with thin wall rubber sealing element

    NASA Astrophysics Data System (ADS)

    Mikhailov, V. P.; Deulin, E. A.

    2017-07-01

    The patented linear motion feedthrough is based on elastic thin rubber walls usage being reinforced with analeptic string fixed in the middle part of the walls. The pneumatic or hydro actuators create linear movement of stock. The length of this movement is two times more the rubber wall length. This flexible wall is a sealing element of feedthrough. The main advantage of device is negligible resistance force that is less then mentioned one in sealing bellows that leads to positioning error decreasing. Nevertheless, the thin wall rubber sealing element (TRE) of the feedthrough is the main unreliable element that was the reason of this element longevity research. The theory and experimental results help to create equation for TRE longevity calculation under vacuum or extra high pressure difference action. The equation was used for TRE longevity determination for hydraulic or vacuum equipment realization also as it helps for gas flow being leaking through the cracks in thin walls of rubber sealing element of linear motion feedthrough calculation.

  14. Evaluation of segmental left ventricular wall motion by equilibrium gated radionuclide ventriculography.

    PubMed

    Van Nostrand, D; Janowitz, W R; Holmes, D R; Cohen, H A

    1979-01-01

    The ability of equilibrium gated radionuclide ventriculography to detect segmental left ventricular (LV) wall motion abnormalities was determined in 26 patients undergoing cardiac catheterization. Multiple gated studies obtained in 30 degrees right anterior oblique and 45 degrees left anterior oblique projections, played back in a movie format, were compared to the corresponding LV ventriculograms. The LV wall in the two projections was divided into eight segments. Each segment was graded as normal, hypokinetic, akinetic, dyskinetic, or indeterminate. Thirteen percent of the segments in the gated images were indeterminate; 24 out of 27 of these were proximal or distal inferior wall segments. There was exact agreement in 86% of the remaining segments. The sensitivity of the radionuclide technique for detecting normal versus any abnormal wall motion was 71%, with a specificity of 99%. Equilibrium gated ventriculography is an excellent noninvasive technique for evaluating segmental LV wall motion. It is least reliable in assessing the proximal inferior wall and interventricular septum.

  15. Segmentation of arterial vessel wall motion to sub-pixel resolution using M-mode ultrasound.

    PubMed

    Fancourt, Craig; Azer, Karim; Ramcharan, Sharmilee L; Bunzel, Michelle; Cambell, Barry R; Sachs, Jeffrey R; Walker, Matthew

    2008-01-01

    We describe a method for segmenting arterial vessel wall motion to sub-pixel resolution, using the returns from M-mode ultrasound. The technique involves measuring the spatial offset between all pairs of scans from their cross-correlation, converting the spatial offsets to relative wall motion through a global optimization, and finally translating from relative to absolute wall motion by interpolation over the M-mode image. The resulting detailed wall distension waveform has the potential to enhance existing vascular biomarkers, such as strain and compliance, as well as enable new ones.

  16. Clinical applications of a quantitative analysis of regional lift ventricular wall motion

    NASA Technical Reports Server (NTRS)

    Leighton, R. F.; Rich, J. M.; Pollack, M. E.; Altieri, P. I.

    1975-01-01

    Observations were summarized which may have clinical application. These were obtained from a quantitative analysis of wall motion that was used to detect both hypokinesis and tardokinesis in left ventricular cineangiograms. The method was based on statistical comparisons with normal values for regional wall motion derived from the cineangiograms of patients who were found not to have heart disease.

  17. Chest Wall Motion during Speech Production in Patients with Advanced Ankylosing Spondylitis

    ERIC Educational Resources Information Center

    Kalliakosta, Georgia; Mandros, Charalampos; Tzelepis, George E.

    2007-01-01

    Purpose: To test the hypothesis that ankylosing spondylitis (AS) alters the pattern of chest wall motion during speech production. Method: The pattern of chest wall motion during speech was measured with respiratory inductive plethysmography in 6 participants with advanced AS (5 men, 1 woman, age 45 plus or minus 8 years, Schober test 1.45 plus or…

  18. Domain wall motion in ferroelectrics: Barkhausen noise

    NASA Astrophysics Data System (ADS)

    Shur, V.; Rumyantsev, E.; Kozhevnikov, V.; Nikolaeva, E.; Shishkin, E.

    2002-03-01

    The switching current noise has been recorded during polarization reversal in single-crystalline gadolinium molybdate (GMO) and lithium tantalate (LT). Analysis of Barkhausen noise (BN) data allows to classify the noise types by determination of the critical indexes and fractal dimensions. BN is manifested as the short pulses during the polarization reversal. We have analyzed the BN data recorded in GMO and LT with various types of controlled domain structure. The data treatment in terms of probability distribution of duration, area and energy of individual pulses reveals the critical behavior typical for the fractal records in time. We used the Fourier transform and Hurst's rescaled range analysis for obtaining the Hurst factor, fractal dimension and classifying the noise types. We investigated by computer simulation the mechanism of sideways motion of 180O domain wall by nucleation at the wall taking into account the nuclei-nuclei interaction. It was shown that the moving domain walls display the fractal shape and their motion is accompanied by Flicker noise, which is in accord with experimental data. The research was made possible in part by Programs "Basic Research in Russian Universities" and "Priority Research in High School. Electronics", by Grant No. 01-02-17443 of RFBR, by Award No.REC-005 of CRDF.

  19. Motion and ranging sensor system for through-the-wall surveillance system

    NASA Astrophysics Data System (ADS)

    Black, Jeffrey D.

    2002-08-01

    A portable Through-the-Wall Surveillance System is being developed for law enforcement, counter-terrorism, and military use. The Motion and Ranging Sensor is a radar that operates in a frequency band that allows for surveillance penetration of most non-metallic walls. Changes in the sensed radar returns are analyzed to detect the human motion that would typically be present during a hostage or barricaded suspect scenario. The system consists of a Sensor Unit, a handheld Remote Display Unit, and an optional laptop computer Command Display Console. All units are battery powered and a wireless link provides command and data communication between units. The Sensor Unit is deployed close to the wall or door through which the surveillance is to occur. After deploying the sensor the operator may move freely as required by the scenario. Up to five Sensor Units may be deployed at a single location. A software upgrade to the Command Display Console is also being developed. This software upgrade will combine the motion detected by multiple Sensor Units and determine and track the location of detected motion in two dimensions.

  20. Thermal-induced domain wall motion of tip-inverted micro/nanodomains in near-stoichiometric LiNbO3 crystals

    NASA Astrophysics Data System (ADS)

    Liu, X. Y.; Kitamura, K.; Liu, Y. M.; Ohuchi, F. S.; Li, J. Y.

    2011-09-01

    Thermal-induced domain wall motion of tip-inverted micro/nanodomains in near-stoichiometric LiNbO3 single crystals was investigated using piezoresponse force microscopy (PFM). The domain wall motion was observed in PFM phase and amplitude images at room temperature after the sample was subjected to a thermal process at a heating temperature higher than 100 °C. In hexagonal domains with only y walls, predetermined nucleation with layer-by-layer growth is the main mechanism for the domain wall motion. In the domains composed of both x walls and y walls, the x walls are more mobile than the y walls, and the domain wall motion starts from the random nucleation of steps along the x walls that finally grow into y walls. The domain wall motion in the near-stoichiometric LiNbO3 crystal is attributed to the energy-preferable domain wall orientation, the pyroelectric effect, and the screening charge variation caused by the thermal process.

  1. Wall shear stress estimation in the aorta: Impact of wall motion, spatiotemporal resolution, and phase noise.

    PubMed

    Zimmermann, Judith; Demedts, Daniel; Mirzaee, Hanieh; Ewert, Peter; Stern, Heiko; Meierhofer, Christian; Menze, Bjoern; Hennemuth, Anja

    2018-04-01

    Wall shear stress (WSS) presents an important parameter for assessing blood flow characteristics and evaluating flow-mediated lesions in the aorta. To investigate the robustness of WSS and oscillatory shear index (OSI) estimation based on 4D flow MRI against vessel wall motion, spatiotemporal resolution, and velocity encoding (VENC). Simulated and prospective. Synthetic 4D flow MRI data of the aorta, simulated using the Lattice-Boltzmann method; in vivo 4D flow MRI data of the aorta from healthy volunteers (n = 11) and patients with congenital heart defects (n = 17). 1.5T; 4D flow MRI with PEAK-GRAPPA acceleration and prospective electrocardiogram triggering. Predicated upon 3D cubic B-splines interpolation of the image velocity field, WSS was estimated in mid-systole, early-diastole, and late-diastole and OSI was derived. We assessed the impact of spatiotemporal resolution and phase noise, and compared results based on tracked-using deformable registration-and static vessel wall location. Bland-Altman analysis to assess WSS/OSI differences; Hausdorff distance (HD) to assess wall motion; and Pearson's correlation coefficient (PCC) to assess correlation of HD with WSS. Synthetic data results show systematic over-/underestimation of WSS when different spatial resolution (mean ± 1.96 SD up to -0.24 ± 0.40 N/m 2 and 0.5 ± 1.38 N/m 2 for 8-fold and 27-fold voxel size, respectively) and VENC-depending phase noise (mean ± 1.96 SD up to 0.31 ± 0.12 N/m 2 and 0.94 ± 0.28 N/m 2 for 2-fold and 4-fold VENC increase, respectively) are given. Neglecting wall motion when defining the vessel wall perturbs WSS estimates to a considerable extent (1.96 SD up to 1.21 N/m 2 ) without systematic over-/underestimation (Bland-Altman mean range -0.06 to 0.05). In addition to sufficient spatial resolution and velocity to noise ratio, accurate tracking of the vessel wall is essential for reliable image-based WSS estimation and should not be

  2. Ferroelectric domain wall motion induced by polarized light

    PubMed Central

    Rubio-Marcos, Fernando; Del Campo, Adolfo; Marchet, Pascal; Fernández, Jose F.

    2015-01-01

    Ferroelectric materials exhibit spontaneous and stable polarization, which can usually be reoriented by an applied external electric field. The electrically switchable nature of this polarization is at the core of various ferroelectric devices. The motion of the associated domain walls provides the basis for ferroelectric memory, in which the storage of data bits is achieved by driving domain walls that separate regions with different polarization directions. Here we show the surprising ability to move ferroelectric domain walls of a BaTiO3 single crystal by varying the polarization angle of a coherent light source. This unexpected coupling between polarized light and ferroelectric polarization modifies the stress induced in the BaTiO3 at the domain wall, which is observed using in situ confocal Raman spectroscopy. This effect potentially leads to the non-contact remote control of ferroelectric domain walls by light. PMID:25779918

  3. Motion Tracking of the Carotid Artery Wall From Ultrasound Image Sequences: a Nonlinear State-Space Approach.

    PubMed

    Gao, Zhifan; Li, Yanjie; Sun, Yuanyuan; Yang, Jiayuan; Xiong, Huahua; Zhang, Heye; Liu, Xin; Wu, Wanqing; Liang, Dong; Li, Shuo

    2018-01-01

    The motion of the common carotid artery (CCA) wall has been established to be useful in early diagnosis of atherosclerotic disease. However, tracking the CCA wall motion from ultrasound images remains a challenging task. In this paper, a nonlinear state-space approach has been developed to track CCA wall motion from ultrasound sequences. In this approach, a nonlinear state-space equation with a time-variant control signal was constructed from a mathematical model of the dynamics of the CCA wall. Then, the unscented Kalman filter (UKF) was adopted to solve the nonlinear state transfer function in order to evolve the state of the target tissue, which involves estimation of the motion trajectory of the CCA wall from noisy ultrasound images. The performance of this approach has been validated on 30 simulated ultrasound sequences and a real ultrasound dataset of 103 subjects by comparing the motion tracking results obtained in this study to those of three state-of-the-art methods and of the manual tracing method performed by two experienced ultrasound physicians. The experimental results demonstrated that the proposed approach is highly correlated with (intra-class correlation coefficient ≥ 0.9948 for the longitudinal motion and ≥ 0.9966 for the radial motion) and well agrees (the 95% confidence interval width is 0.8871 mm for the longitudinal motion and 0.4159 mm for the radial motion) with the manual tracing method on real data and also exhibits high accuracy on simulated data (0.1161 ~ 0.1260 mm). These results appear to demonstrate the effectiveness of the proposed approach for motion tracking of the CCA wall.

  4. Robust estimation of carotid artery wall motion using the elasticity-based state-space approach.

    PubMed

    Gao, Zhifan; Xiong, Huahua; Liu, Xin; Zhang, Heye; Ghista, Dhanjoo; Wu, Wanqing; Li, Shuo

    2017-04-01

    The dynamics of the carotid artery wall has been recognized as a valuable indicator to evaluate the status of atherosclerotic disease in the preclinical stage. However, it is still a challenge to accurately measure this dynamics from ultrasound images. This paper aims at developing an elasticity-based state-space approach for accurately measuring the two-dimensional motion of the carotid artery wall from the ultrasound imaging sequences. In our approach, we have employed a linear elasticity model of the carotid artery wall, and converted it into the state space equation. Then, the two-dimensional motion of carotid artery wall is computed by solving this state-space approach using the H ∞ filter and the block matching method. In addition, a parameter training strategy is proposed in this study for dealing with the parameter initialization problem. In our experiment, we have also developed an evaluation function to measure the tracking accuracy of the motion of the carotid artery wall by considering the influence of the sizes of the two blocks (acquired by our approach and the manual tracing) containing the same carotid wall tissue and their overlapping degree. Then, we have compared the performance of our approach with the manual traced results drawn by three medical physicians on 37 healthy subjects and 103 unhealthy subjects. The results have showed that our approach was highly correlated (Pearson's correlation coefficient equals 0.9897 for the radial motion and 0.9536 for the longitudinal motion), and agreed well (width the 95% confidence interval is 89.62 µm for the radial motion and 387.26 µm for the longitudinal motion) with the manual tracing method. We also compared our approach to the three kinds of previous methods, including conventional block matching methods, Kalman-based block matching methods and the optical flow. Altogether, we have been able to successfully demonstrate the efficacy of our elasticity-model based state-space approach (EBS) for

  5. Remarkably enhanced current-driven 360° domain wall motion in nanostripe by tuning in-plane biaxial anisotropy.

    PubMed

    Su, Yuanchang; Weng, Lianghao; Dong, Wenjun; Xi, Bin; Xiong, Rui; Hu, Jingguo

    2017-10-17

    By micromagnetic simulations, we study the current-driven 360° domain wall (360DW) motion in ferromagnetic nanostripe with an in-plane biaxial anisotropy. We observe the critical annihilation current of 360° domain wall can be enhanced through such a type of anisotropy, the reason of which is the suppression of out-of-plane magnetic moments generated simultaneously with domain-wall motion. In details, We have found that the domain-wall width is only related to K y  - K x , with K x(y) the anisotropy constant in x(y) direction. Taking domain-wall width into consideration, a prior choice is to keep K y  ≈ K x with large enough K. The mode of domain-wall motion has been investigated as well. The traveling-wave-motion region increases with K, while the average DW velocity is almost unchanged. Another noteworthy feature is that a Walker-breakdown-like motion exists before annihilation. In this region, though domain wall moves with an oscillating behavior, the average velocity does not reduce dramatically, but even rise again for a large K.

  6. Ab initio study of edge effect on relative motion of walls in carbon nanotubes

    NASA Astrophysics Data System (ADS)

    Popov, Andrey M.; Lebedeva, Irina V.; Knizhnik, Andrey A.; Lozovik, Yurii E.; Potapkin, Boris V.

    2013-01-01

    Interwall interaction energies of double-walled nanotubes with long inner and short outer walls are calculated as functions of coordinates describing relative rotation and displacement of the walls using van der Waals corrected density functional theory. The magnitude of corrugation and the shape of the potential energy relief are found to be very sensitive to changes of the shorter wall length at subnanometer scale and atomic structure of the edges if at least one of the walls is chiral. Threshold forces required to start relative motion of the short walls and temperatures at which the transition between diffusive and free motion of the short walls takes place are estimated. The edges are also shown to provide a considerable contribution to the barrier to relative rotation of commensurate nonchiral walls. For such walls, temperatures of orientational melting, i.e., the crossover from rotational diffusion to free relative rotation, are estimated. The possibility to produce nanotube-based bolt/nut pairs and nanobearings is discussed.

  7. Annealing effect on current-driven domain wall motion in Pt/[Co/Ni] wire

    NASA Astrophysics Data System (ADS)

    Furuta, Masaki; Liu, Yang; Sepehri-Amin, Hossein; Hono, Kazuhiro; Zhu, Jian-Gang Jimmy

    2017-09-01

    The annealing effect on the efficiency of current-driven domain wall motion governed by the spin Hall effect in perpendicularly magnetized Pt/[Co/Ni] wires is investigated experimentally. Important physical parameters, such as the Dzyaloshinskii-Moriya Interaction (DMI), spin Hall angle, and perpendicular anisotropy field strength, for the domain wall motion are all characterized at each annealing temperature. It is found that annealing of wires at temperatures over 120 °C causes significant reduction of the domain wall velocity. Energy dispersive X-ray spectroscopy analysis shows pronounced Co diffusion across the Pt/Co interface resulted from annealing at relatively high temperatures. The combined modeling study shows that the reduction of DMI caused by annealing is mostly responsible for the domain wall velocity reduction due to annealing.

  8. Comparison of Current and Field Driven Domain Wall Motion in Beaded Permalloy Nanowires

    NASA Astrophysics Data System (ADS)

    Lage, Enno; Dutta, Sumit; Ross, Caroline A.

    2015-03-01

    Domain wall based devices are promising candidates for non-volatile memory devices with no static power consumption. A common approach is the use of (field assisted) current driven domain wall motion in magnetic nanowires. In such systems local variations in linewidth act as obstacles for propagating domain walls. In this study we compare simulated field driven and current driven domain wall motion in permalloy nanowires with anti-notches. The simulations were obtained using the Object Oriented MicroMagnetics Framework (OOMMF). The wires with a constant thickness of 8 nm exhibit linewidths ranging from 40 nm to 300 nm. Circular shaped anti-notches extend the linewidth locally by 10% to 30% and raise information about the domain wall propagation in such beaded nanowires. The results are interpreted in terms of the observed propagation behavior and summarized in maps indicating ranges of different ability to overcome the pinning caused by anti-notches of different sizes. Furthermore, regimes of favored domain wall type (transverse walls or vortex walls) and complex propagation effects like walker breakdown behavior or dynamic change between domain wall structures are identified The authors thank the German Academic Exchange Service (DAAD) for funding.

  9. Value of gated SPECT in the analysis of regional wall motion of the interventricular septum after coronary artery bypass grafting.

    PubMed

    Giubbini, Raffaele; Rossini, Pierluigi; Bertagna, Francesco; Bosio, Giovanni; Paghera, Barbara; Pizzocaro, Claudio; Canclini, Silvana; Terzi, Arturo; Germano, Guido

    2004-10-01

    The aim of this study was the evaluation of septal wall motion, perfusion and wall thickening after CABG in two groups of consecutive patients, one with grafted left anterior coronary artery and no history of myocardial infarction, and the other with previous anteroseptal myocardial infarction and impaired septal motion before surgery. The issue addressed was the ability of gated SPECT to differentiate between true paradoxical septal motion, characterised by paradoxical wall motion, depressed ejection fraction (EF), poor viability and compromised wall thickening, and pseudo-paradoxical motion, characterised by abnormal wall motion and regional EF but preserved perfusion and wall thickening. One hundred and thirty-two patients with previous anterior myocardial infarction, 82 patients with left anterior descending coronary disease and no history of myocardial infarction and 27 normal subjects underwent rest gated SPECT after 99mTc-sestamibi injection, according to the standard QGS protocol. Quantitative regional EF, regional perfusion, regional wall motion and regional wall thickening were determined using a 20-segment model. Despite the presence of similar regional wall motion impairment in patients with and patients without septal infarction, in terms of regional EF (2.5%+/-3% vs 1.9%+/-4.9% p=NS) and inward septal motion (3+/-4.9 mm vs 2.3+/-6.1 mm p=NS), significant differences were observed in both perfusion (74.7%+/-6.2% vs 63.3%+/-13%, p>0.0001) and regional wall thickening (17.2%+/-7.4% vs 12.6%+/-7.2%, p>0.0001). Gated SPECT with perfusion tracers can reliably differentiate pseudo-paradoxical from true paradoxical septal motion in patients with previous CABG, and it may be the method of choice for evaluating left ventricular performance in this patient population.

  10. Fractional Brownian motion with a reflecting wall.

    PubMed

    Wada, Alexander H O; Vojta, Thomas

    2018-02-01

    Fractional Brownian motion, a stochastic process with long-time correlations between its increments, is a prototypical model for anomalous diffusion. We analyze fractional Brownian motion in the presence of a reflecting wall by means of Monte Carlo simulations. Whereas the mean-square displacement of the particle shows the expected anomalous diffusion behavior 〈x^{2}〉∼t^{α}, the interplay between the geometric confinement and the long-time memory leads to a highly non-Gaussian probability density function with a power-law singularity at the barrier. In the superdiffusive case α>1, the particles accumulate at the barrier leading to a divergence of the probability density. For subdiffusion α<1, in contrast, the probability density is depleted close to the barrier. We discuss implications of these findings, in particular, for applications that are dominated by rare events.

  11. Fractional Brownian motion with a reflecting wall

    NASA Astrophysics Data System (ADS)

    Wada, Alexander H. O.; Vojta, Thomas

    2018-02-01

    Fractional Brownian motion, a stochastic process with long-time correlations between its increments, is a prototypical model for anomalous diffusion. We analyze fractional Brownian motion in the presence of a reflecting wall by means of Monte Carlo simulations. Whereas the mean-square displacement of the particle shows the expected anomalous diffusion behavior ˜tα , the interplay between the geometric confinement and the long-time memory leads to a highly non-Gaussian probability density function with a power-law singularity at the barrier. In the superdiffusive case α >1 , the particles accumulate at the barrier leading to a divergence of the probability density. For subdiffusion α <1 , in contrast, the probability density is depleted close to the barrier. We discuss implications of these findings, in particular, for applications that are dominated by rare events.

  12. Minimization of Ohmic losses for domain wall motion in ferromagnetic nanowires

    NASA Astrophysics Data System (ADS)

    Abanov, Artem; Tretiakov, Oleg; Liu, Yang

    2011-03-01

    We study current-induced domain-wall motion in a narrow ferromagnetic wire. We propose a way to move domain walls with a resonant time-dependent current which dramatically decreases the Ohmic losses in the wire and allows driving of the domain wall with higher speed without burning the wire. For any domain wall velocity we find the time-dependence of the current needed to minimize the Ohmic losses. Below a critical domain-wall velocity specified by the parameters of the wire the minimal Ohmic losses are achieved by dc current. Furthermore, we identify the wire parameters for which the losses reduction from its dc value is the most dramatic. This work was supported by the NSF Grant No. 0757992 and Welch Foundation (A-1678).

  13. Minimization of Ohmic Losses for Domain Wall Motion in a Ferromagnetic Nanowire

    NASA Astrophysics Data System (ADS)

    Tretiakov, O. A.; Liu, Y.; Abanov, Ar.

    2010-11-01

    We study current-induced domain-wall motion in a narrow ferromagnetic wire. We propose a way to move domain walls with a resonant time-dependent current which dramatically decreases the Ohmic losses in the wire and allows driving of the domain wall with higher speed without burning the wire. For any domain-wall velocity we find the time dependence of the current needed to minimize the Ohmic losses. Below a critical domain-wall velocity specified by the parameters of the wire the minimal Ohmic losses are achieved by dc current. Furthermore, we identify the wire parameters for which the losses reduction from its dc value is the most dramatic.

  14. Local Nanomechanical Motion of the Cell Wall of Saccharomyces cerevisiae

    NASA Astrophysics Data System (ADS)

    Pelling, Andrew E.; Sehati, Sadaf; Gralla, Edith B.; Valentine, Joan S.; Gimzewski, James K.

    2004-08-01

    We demonstrate that the cell wall of living Saccharomyces cerevisiae (baker's yeast) exhibits local temperature-dependent nanomechanical motion at characteristic frequencies. The periodic motions in the range of 0.8 to 1.6 kHz with amplitudes of ~3 nm were measured using the cantilever of an atomic force microscope (AFM). Exposure of the cells to a metabolic inhibitor causes the periodic motion to cease. From the strong frequency dependence on temperature, we derive an activation energy of 58 kJ/mol, which is consistent with the cell's metabolism involving molecular motors such as kinesin, dynein, and myosin. The magnitude of the forces observed (~10 nN) suggests concerted nanomechanical activity is operative in the cell.

  15. Does quantitative left ventricular regional wall motion change after fibrous tissue resection in endomyocardial fibrosis?

    PubMed

    Salemi, Vera Maria Cury; Fernandes, Fabio; Sirvente, Raquel; Nastari, Luciano; Rosa, Leonardo Vieira; Ferreira, Cristiano A; Pena, José Luiz Barros; Picard, Michael H; Mady, Charles

    2009-01-01

    We compared left ventricular regional wall motion, the global left ventricular ejection fraction, and the New York Heart Association functional class pre- and postoperatively. Endomyocardial fibrosis is characterized by fibrous tissue deposition in the endomyocardium of the apex and/or inflow tract of one or both ventricles. Although left ventricular global systolic function is preserved, patients exhibit wall motion abnormalities in the apical and inferoapical regions. Fibrous tissue resection in New York Heart Association FC III and IV endomyocardial fibrosis patients has been shown to decrease morbidity and mortality. We prospectively studied 30 patients (20 female, 30+/-10 years) before and 5+/-8 months after surgery. The left ventricular ejection fraction was determined using the area-length method. Regional left ventricular motion was measured by the centerline method. Five left ventricular segments were analyzed pre- and postoperatively. Abnormality was expressed in units of standard deviation from the mean motion in a normal reference population. Left ventricular wall motion in the five regions did not differ between pre- and postoperative measurements. Additionally, the left ventricular ejection fraction did not change after surgery (0.45+/-0.13% x 0.43+/-0.12% pre- and postoperatively, respectively). The New York Heart Association functional class improved to class I in 40% and class II in 43% of patients postoperatively (p<0.05). Although endomyocardial fibrosis patients have improved clinical symptoms after surgery, the global left ventricular ejection fraction and regional wall motion in these patients do not change. This finding suggests that other explanations, such as improvements in diastolic function, may be operational.

  16. Automated Quantification of the Landing Error Scoring System With a Markerless Motion-Capture System.

    PubMed

    Mauntel, Timothy C; Padua, Darin A; Stanley, Laura E; Frank, Barnett S; DiStefano, Lindsay J; Peck, Karen Y; Cameron, Kenneth L; Marshall, Stephen W

    2017-11-01

      The Landing Error Scoring System (LESS) can be used to identify individuals with an elevated risk of lower extremity injury. The limitation of the LESS is that raters identify movement errors from video replay, which is time-consuming and, therefore, may limit its use by clinicians. A markerless motion-capture system may be capable of automating LESS scoring, thereby removing this obstacle.   To determine the reliability of an automated markerless motion-capture system for scoring the LESS.   Cross-sectional study.   United States Military Academy.   A total of 57 healthy, physically active individuals (47 men, 10 women; age = 18.6 ± 0.6 years, height = 174.5 ± 6.7 cm, mass = 75.9 ± 9.2 kg).   Participants completed 3 jump-landing trials that were recorded by standard video cameras and a depth camera. Their movement quality was evaluated by expert LESS raters (standard video recording) using the LESS rubric and by software that automates LESS scoring (depth-camera data). We recorded an error for a LESS item if it was present on at least 2 of 3 jump-landing trials. We calculated κ statistics, prevalence- and bias-adjusted κ (PABAK) statistics, and percentage agreement for each LESS item. Interrater reliability was evaluated between the 2 expert rater scores and between a consensus expert score and the markerless motion-capture system score.   We observed reliability between the 2 expert LESS raters (average κ = 0.45 ± 0.35, average PABAK = 0.67 ± 0.34; percentage agreement = 0.83 ± 0.17). The markerless motion-capture system had similar reliability with consensus expert scores (average κ = 0.48 ± 0.40, average PABAK = 0.71 ± 0.27; percentage agreement = 0.85 ± 0.14). However, reliability was poor for 5 LESS items in both LESS score comparisons.   A markerless motion-capture system had the same level of reliability as expert LESS raters, suggesting that an automated system can accurately assess movement. Therefore, clinicians can use

  17. The stability of steady motion of magnetic domain wall: Role of higher-order spin-orbit torques

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    He, Peng-Bin, E-mail: hepengbin@hnu.edu.cn; Yan, Han; Cai, Meng-Qiu

    The steady motion of magnetic domain wall driven by spin-orbit torques is investigated analytically in the heavy/ferromagnetic metal nanowires for three cases with a current transverse to the in-plane and perpendicular easy axis, and along the in-plane easy axis. By the stability analysis of Walker wall profile, we find that if including the higher-order spin-orbit torques, the Walker breakdown can be avoided in some parameter regions of spin-orbit torques with a current transverse to or along the in-plane easy axis. However, in the case of perpendicular anisotropy, even considering the higher-order spin-orbit torques, the velocity of domain wall cannot bemore » efficiently enhanced by the current. Furthermore, the direction of wall motion is dependent on the configuration and chirality of domain wall with a current along the in-plane easy axis or transverse to the perpendicular one. Especially, the direction of motion can be controlled by the initial chirality of domain wall. So, if only involving the spin-orbit mechanism, it is preferable to adopt the scheme of a current along the in-plane easy axis for enhancing the velocity and controlling the direction of domain wall.« less

  18. Numerical simulation of microcarrier motion in a rotating wall vessel bioreactor.

    PubMed

    Ju, Zhi-Hao; Liu, Tian-Qing; Ma, Xue-Hu; Cui, Zhan-Feng

    2006-06-01

    To analyze the forces of rotational wall vessel (RWV) bioreactor on small tissue pieces or microcarrier particles and to determine the tracks of microcarrier particles in RWV bioreactor. The motion of the microcarrier in the rotating wall vessel (RWV) bioreactor with both the inner and outer cylinders rotating was modeled by numerical simulation. The continuous trajectory of microcarrier particles, including the possible collision with the wall was obtained. An expression between the minimum rotational speed difference of the inner and outer cylinders and the microcarrier particle or aggregate radius could avoid collisions with either wall. The range of microcarrier radius or tissue size, which could be safely cultured in the RWV bioreactor, in terms of shear stress level, was determined. The model works well in describing the trajectory of a heavier microcarrier particle in rotating wall vessel.

  19. Motion of a Spherical Domain Wall and the Large-Scale Structure Formation

    NASA Astrophysics Data System (ADS)

    Yamamoto, K.; Tomita, K.

    1991-11-01

    The evolution of a wall-like structure in the universe is investigated by assuming a simplified model of a domain wall. The domain wall is approximated as a thin spherical shell with domain wall-like matter, which is assumed to interact with dust-like dark matter in an entirely inelastic manner, and its motion in an expanding universe is numerically studied in the general-relativistic treatment. We evaluate the lifetime of the wall, which is defined as the characteristic time for the wall to shrink due to its own tension. It is necessary that this time is not smaller than the cosmic age, in order that the walls avoid the collapse to the present time and play an important role in the structure formation of the universe. It is shown that, in spite of the above interaction, the strong restriction is imposed on the surface density of the domain walls and the allowed values are too small to have any influences on the background model.

  20. Changes in sitting posture induce multiplanar changes in chest wall shape and motion with breathing.

    PubMed

    Lee, Linda-Joy; Chang, Angela T; Coppieters, Michel W; Hodges, Paul W

    2010-03-31

    This study examined the effect of sitting posture on regional chest wall shape in three dimensions, chest wall motion (measured with electromagnetic motion analysis system), and relative contributions of the ribcage and abdomen to tidal volume (%RC/V(t)) (measured with inductance plethysmography) in 7 healthy volunteers. In seven seated postures, increased dead space breathing automatically increased V(t) (to 1.5 V(t)) to match volume between conditions and study the effects of posture independent of volume changes. %RC/V(t) (p<0.05), chest wall shape (p<0.05) and motion during breathing differed between postures. Compared to a reference posture, movement at the 9th rib lateral diameter increased in the thoracolumbar extension posture (p<0.008). In slumped posture movement at the AP diameters at T1 and axilla increased (p<0.00001). Rotation postures decreased movement in the lateral diameter at the axilla (p<0.0007). The data show that single plane changes in sitting posture alter three-dimensional ribcage configuration and chest wall kinematics during breathing, while maintaining constant respiratory function. Copyright 2010 Elsevier B.V. All rights reserved.

  1. Influence of left ventricular hypertrophy and geometry on diagnostic accuracy of wall motion and perfusion magnetic resonance during dobutamine stress.

    PubMed

    Gebker, Rolf; Mirelis, Jesus G; Jahnke, Cosima; Hucko, Thomas; Manka, Robert; Hamdan, Ashraf; Schnackenburg, Bernhard; Fleck, Eckart; Paetsch, Ingo

    2010-09-01

    The purpose of this study was to determine the influence of left ventricular (LV) hypertrophy and geometry on the diagnostic accuracy of wall motion and additional perfusion imaging during high-dose dobutamine/atropine stress magnetic resonance for the detection of coronary artery disease. Combined dobutamine stress magnetic resonance (DSMR)-wall motion and DSMR-perfusion imaging was performed in a single session in 187 patients scheduled for invasive coronary angiography. Patients were classified into 4 categories on the basis of LV mass (normal, ≤ 81 g/m(2) in men and ≤ 62 g/m(2) in women) and relative wall thickness (RWT) (normal, <0.45) as follows: normal geometry (normal mass, normal RWT), concentric remodeling (normal mass, increased RWT), concentric hypertrophy (increased mass, increased RWT), and eccentric hypertrophy (increased mass, normal RWT). Wall motion and perfusion images were interpreted sequentially, with observers blinded to other data. Significant coronary artery disease was defined as ≥ 70% stenosis. In patients with increased LV concentricity (defined by an RWT ≥ 0.45), sensitivity and accuracy of DSMR-wall motion were significantly reduced (63% and 73%, respectively; P<0.05) compared with patients without increased LV concentricity (90% and 88%, respectively; P<0.05). Although accuracy of DSMR-perfusion was higher than that of DSMR-wall motion in patients with concentric hypertrophy (82% versus 71%; P < 0.05), accuracy of DSMR-wall motion was superior to DSMR-perfusion (90% versus 85%; P < 0.05) in patients with eccentric hypertrophy. The accuracy of DSMR-wall motion is influenced by LV geometry. In patients with concentric remodeling and concentric hypertrophy, additional first-pass perfusion imaging during high-dose dobutamine stress improves the diagnostic accuracy for the detection of coronary artery disease.

  2. Spin-orbit-torque-induced magnetic domain wall motion in Ta/CoFe nanowires with sloped perpendicular magnetic anisotropy.

    PubMed

    Zhang, Yue; Luo, Shijiang; Yang, Xiaofei; Yang, Chang

    2017-05-17

    In materials with the gradient of magnetic anisotropy, spin-orbit-torque-induced magnetization behaviour has attracted attention because of its intriguing scientific principle and potential application. Most of the magnetization behaviours microscopically originate from magnetic domain wall motion, which can be precisely depicted using the standard cooperative coordinate method (CCM). However, the domain wall motion in materials with the gradient of magnetic anisotropy using the CCM remains lack of investigation. In this paper, by adopting CCM, we established a set of equations to quantitatively depict the spin-orbit-torque-induced motion of domain walls in a Ta/CoFe nanotrack with weak Dzyaloshinskii-Moriya interaction and magnetic anisotropy gradient. The equations were solved numerically, and the solutions are similar to those of a micromagnetic simulation. The results indicate that the enhanced anisotropy along the track acts as a barrier to inhibit the motion of the domain wall. In contrast, the domain wall can be pushed to move in a direction with reduced anisotropy, with the velocity being accelerated by more than twice compared with that for the constant anisotropy case. This substantial velocity manipulation by anisotropy engineering is important in designing novel magnetic information devices with high reading speeds.

  3. Analysis of Human's Motions Based on Local Mean Decomposition in Through-wall Radar Detection

    NASA Astrophysics Data System (ADS)

    Lu, Qi; Liu, Cai; Zeng, Zhaofa; Li, Jing; Zhang, Xuebing

    2016-04-01

    Observation of human motions through a wall is an important issue in security applications and search-and rescue. Radar has advantages in looking through walls where other sensors give low performance or cannot be used at all. Ultrawideband (UWB) radar has high spatial resolution as a result of employment of ultranarrow pulses. It has abilities to distinguish the closely positioned targets and provide time-lapse information of targets. Moreover, the UWB radar shows good performance in wall penetration when the inherently short pulses spread their energy over a broad frequency range. Human's motions show periodic features including respiration, swing arms and legs, fluctuations of the torso. Detection of human targets is based on the fact that there is always periodic motion due to breathing or other body movements like walking. The radar can gain the reflections from each human body parts and add the reflections at each time sample. The periodic movements will cause micro-Doppler modulation in the reflected radar signals. Time-frequency analysis methods are consider as the effective tools to analysis and extract micro-Doppler effects caused by the periodic movements in the reflected radar signal, such as short-time Fourier transform (STFT), wavelet transform (WT), and Hilbert-Huang transform (HHT).The local mean decomposition (LMD), initially developed by Smith (2005), is to decomposed amplitude and frequency modulated signals into a small set of product functions (PFs), each of which is the product of an envelope signal and a frequency modulated signal from which a time-vary instantaneous phase and instantaneous frequency can be derived. As bypassing the Hilbert transform, the LMD has no demodulation error coming from window effect and involves no negative frequency without physical sense. Also, the instantaneous attributes obtained by LMD are more stable and precise than those obtained by the empirical mode decomposition (EMD) because LMD uses smoothed local

  4. Effect of thoracic epidural anesthesia combined with general anesthesia on segmental wall motion assessed by transesophageal echocardiography.

    PubMed

    Saada, M; Catoire, P; Bonnet, F; Delaunay, L; Gormezano, G; Macquin-Mavier, I; Brun, P

    1992-09-01

    Patients scheduled for vascular surgery are considered at risk for perioperative cardiac complications. Choice of anesthetic in such patients is guided by a desire not to adversely affect myocardial function. On the basis of data from laboratory studies, thoracic epidural anesthesia (TEA) has been advocated to prevent myocardial ischemia. The aim of this study was to assess whether TEA combined with general anesthesia has any effect on segmental wall motion (SWM) monitored by transesophageal echocardiography in these patients. Patients received alfentanil, midazolam, vecuronium, and 50% N2O in oxygen, and ventilation was controlled after orotracheal intubation; 12.5 mL of 2% lidocaine HCl was injected through an epidural catheter placed at T6-7 or T7-8. Hemodynamic measurements and transesophageal echocardiographic recordings were obtained before and 10, 20, 30, 40, and 60 min after lidocaine injection. Segmental wall motion was graded a posteriori by two independent experts on a predetermined scale (from 1 = normal to 5 = dyskinesia). A decrease greater than or equal to 2 grades was considered an SWM abnormality indicative of ischemia. Thoracic epidural anesthesia induced a decrease in systemic arterial blood pressure, heart rate, and cardiac index. The SWM score decreased slightly from 1.34 +/- 0.68 to 1.27 +/- 0.64 (mean +/- SD) (at 10 and 20 min, respectively) (P less than 0.05). Patients were a posteriori analyzed according to whether they had documented coronary artery disease or not. The SWM score before TEA was significantly higher in patients with documented coronary artery disease (1.51 +/- 0.88 vs 1.17 +/- 0.51, respectively; P less than 0.05) and did not change significantly after TEA.(ABSTRACT TRUNCATED AT 250 WORDS)

  5. Short-term effect of volume recruitment-derecruitment manoeuvre on chest-wall motion in Duchenne muscular dystrophy.

    PubMed

    Meric, Henri; Falaize, Line; Pradon, Didier; Lacombe, Matthieu; Petitjean, Michel; Orlikowski, David; Prigent, Hélène; Lofaso, Frédéric

    2017-05-01

    Because progressive respiratory muscle weakness leads to decreased chest-wall motion with eventual ribcage stiffening, the purpose was to compare vital capacity (VC) and contributions of chest-wall compartments before and after volume recruitment-derecruitment manoeuvres (VRDM) in Duchenne muscular dystrophy (DMD). We studied nine patients with DMD and VC lower than 30% of predicted. VRDM was performed using 15 insufflations-exsufflations of +30 to -30 cmH 2 O. VC and three-dimensional chest-wall motion were measured, as well as oxygen saturation, transcutaneous partial pressure of carbon dioxide and the rapid shallow breathing index (respiratory rate/tidal volume) before (baseline) and immediately and 1 hour after VRDM. VC increased significantly immediately after VRDM (108% ± 7% of baseline, p = 0.018) but returned to baseline within 1 hour, and the rapid shallow breathing index increased significantly. The non-dominant side systematically increased immediately after VRDM ( p = 0.0077), and in the six patients with abnormal breathing asymmetry (difference >10% of VC) at baseline, this asymmetry was corrected immediately and/or 1 hour after VRDM. VRDM improved VC and reduced chest-wall motion asymmetry, but this beneficial effect waned rapidly with respiratory muscle fatigue, suggesting that VRDM may need to be repeated during the day to produce lasting benefits.

  6. Inspiratory flow rate, not type of incentive spirometry device, influences chest wall motion in healthy individuals.

    PubMed

    Chang, Angela T; Palmer, Kerry R; McNaught, Jessie; Thomas, Peter J

    2010-08-01

    This study investigated the effect of flow rates and spirometer type on chest wall motion in healthy individuals. Twenty-one healthy volunteers completed breathing trials to either two times tidal volume (2xV(T)) or inspiratory capacity (IC) at high, low, or natural flow rates, using a volume- or flow-oriented spirometer. The proportions of rib cage movement to tidal volume (%RC/V(T)), chest wall diameters, and perceived level of exertion (RPE) were compared. Low and natural flow rates resulted in significantly lower %RC/V(T) compared to high flow rate trials (p=0.001) at 2xV(T). Low flow trials also resulted in significantly less chest wall motion in the upper anteroposterior direction than high and natural flow rates (p<0.001). At IC, significantly greater movement occurred in the abdominal lateral direction during low flow compared to high and natural flow trials (both p<0.003). RPE was lower for the low flow trials compared to high flow trials at IC and 2xV(T) (p<0.01). In healthy individuals, inspiratory flow (not device type) during incentive spirometry determines the resultant breathing pattern. High flow rates result in greater chest wall motion than low flow rates.

  7. Processive motions of MreB micro-filaments coordinate cell wall growth

    NASA Astrophysics Data System (ADS)

    Garner, Ethan

    2012-02-01

    Rod-shaped bacteria elongate by the action of cell-wall synthesis complexes linked to underlying dynamic MreB filaments, but how these proteins function to allow continued elongation as a rod remains unknown. To understand how the movement of these filaments relates to cell wall synthesis, we characterized the dynamics of MreB and the cell wall elongation machinery using high-resolution particle tracking in Bacillus subtilis. We found that both MreB and the elongation machinery move in linear paths across the cell, moving at similar rates (˜20nm / second) and angles to the cell body, suggesting they function as single complexes. These proteins move circumferentially around the cell, principally perpendicular to its length. We find that the motions of these complexes are independent, as they can pause and reverse,and also as nearby complexes move independently in both directions across one surface of the cell. Inhibition of cell wall synthesis with antibiotics or depletions in the cell wall synthesis machinery blocked MreB movement, suggesting that the cell wall synthetic machinery is the motor in this system. We propose that bacteria elongate by the uncoordinated, circumferential movements of synthetic complexes that span the plasma membrane and insert radial hoops of new peptidoglycan during their transit.

  8. Microwave fields driven domain wall motions in antiferromagnetic nanowires

    NASA Astrophysics Data System (ADS)

    Chen, Z. Y.; Yan, Z. R.; Zhang, Y. L.; Qin, M. H.; Fan, Z.; Lu, X. B.; Gao, X. S.; Liu, J.-M.

    2018-06-01

    In this work, we study the microwave field driven domain wall (DW) motion in an antiferromagnetic nanowire, using the numerical calculations based on a classical Heisenberg spin model with the biaxial magnetic anisotropy. We show that a proper combination of a static magnetic field plus an oscillating field perpendicular to the nanowire axis is sufficient to drive the DW propagation along the nanowire. More importantly, the drift velocity at the resonance frequency is comparable to that induced by temperature gradients, suggesting that microwave field can be a very promising tool to control DW motions in antiferromagnetic nanostructures. The dependences of resonance frequency and drift velocity on the static and oscillating fields, the axial anisotropy, and the damping constant are discussed in details. Furthermore, the optimal orientations of the field are also numerically determined and explained. This work provides useful information for the spin dynamics in antiferromagnetic nanostructures for spintronics applications.

  9. Correlation between the viscoelastic heterogeneity and the domain wall motion of Fe-based metallic glass

    NASA Astrophysics Data System (ADS)

    Ouyang, S.; Song, L. J.; Liu, Y. H.; Huo, J. T.; Wang, J. Q.; Xu, W.; Li, J. L.; Wang, C. T.; Wang, X. M.; Li, R. W.

    2018-06-01

    The soft magnetic properties of Fe-based metallic glasses are reduced significantly by external and residual stresses, e.g., the susceptibility decreases and coercivity increases, which limits their application severely. Unraveling the micromechanism of how the stress influences the soft magnetic properties is of great help for enhancing the performance of Fe-based metallic glasses. In this work, we investigate the effect of viscoelastic heterogeneity on the motion of magnetic domain wall surrounding nanoindentations. Compared to the matrix, dissipation of the viscoelastic heterogeneity increases toward the nanoindentation. Meanwhile, the motion of domain wall under external magnetic field becomes more difficult toward the nanoindentations. A correlation between the viscoelastic dissipation and the moving ability of magnetic domain walls is observed, which can be well fitted using magnetoelastic coupling theory. This suggests that manipulating the microscale viscoelastic heterogeneity is probably a helpful strategy for enhancing the soft magnetic properties of metallic glasses.

  10. Assessment of dyssynchronous wall motion during acute myocardial ischemia using velocity vector imaging.

    PubMed

    Masuda, Kasumi; Asanuma, Toshihiko; Taniguchi, Asuka; Uranishi, Ayumi; Ishikura, Fuminobu; Beppu, Shintaro

    2008-03-01

    The purpose of this study was to investigate the diagnostic value of velocity vector imaging (VVI) for detecting acute myocardial ischemia and whether VVI can accurately demonstrate the spatial extent of ischemic risk area. Using a tracking algorithm, VVI can display velocity vectors of regional wall motion overlaid onto the B-mode image and allows the quantitative assessment of myocardial mechanics. However, its efficacy for diagnosing myocardial ischemia has not been evaluated. In 18 dogs with flow-limiting stenosis and/or total occlusion of the coronary artery, peak systolic radial velocity (V(SYS)), radial velocity at mitral valve opening (V(MVO)), peak systolic radial strain, and the percent change in wall thickening (%WT) were measured in the normal and risk areas and compared to those at baseline. Sensitivity and specificity for detecting the stenosis and occlusion were analyzed in each parameter. The area of inward velocity vectors at mitral valve opening (MVO) detected by VVI was compared to the risk area derived from real-time myocardial contrast echocardiography (MCE). Twelve image clips were randomly selected from the baseline, stenosis, and occlusions to determine the intra- and inter-observer agreement for the VVI parameters. The left circumflex coronary flow was reduced by 44.3 +/- 9.0% during stenosis and completely interrupted during occlusion. During coronary artery occlusion, inward motion at MVO was observed in the risk area. Percent WT, peak systolic radial strain, V(SYS), and V(MVO) changed significantly from values at baseline. During stenosis, %WT, peak systolic radial strain, and V(SYS) did not differ from those at baseline; however, V(MVO) was significantly increased (-0.12 +/- 0.60 cm/s vs. -0.96 +/- 0.55 cm/s, p = 0.015). Sensitivity and specificity of V(MVO) for detecting ischemia were superior to those of other parameters. The spatial extent of inward velocity vectors at MVO correlated well with that of the risk area derived from MCE

  11. Dynamic radionuclide determination of regional left ventricular wall motion using a new digital imaging device

    NASA Technical Reports Server (NTRS)

    Steele, P.; Kirch, D.

    1975-01-01

    In 47 men with arteriographically defined coronary artery disease comparative studies of left ventricular ejection fraction and segmental wall motion were made with radionuclide data obtained from the image intensifier camera computer system and with contrast cineventriculography. The radionuclide data was digitized and the images corresponding to left ventricular end-diastole and end-systole were identified from the left ventricular time-activity curve. The left ventricular end-diastolic and end-systolic images were subtracted to form a silhouette difference image which described wall motion of the anterior and inferior left ventricular segments. The image intensifier camera allows manipulation of dynamically acquired radionuclide data because of the high count rate and consequently improved resolution of the left ventricular image.

  12. Spatio-temporal characteristics of large scale motions in a turbulent boundary layer from direct wall shear stress measurement

    NASA Astrophysics Data System (ADS)

    Pabon, Rommel; Barnard, Casey; Ukeiley, Lawrence; Sheplak, Mark

    2016-11-01

    Particle image velocimetry (PIV) and fluctuating wall shear stress experiments were performed on a flat plate turbulent boundary layer (TBL) under zero pressure gradient conditions. The fluctuating wall shear stress was measured using a microelectromechanical 1mm × 1mm floating element capacitive shear stress sensor (CSSS) developed at the University of Florida. The experiments elucidated the imprint of the organized motions in a TBL on the wall shear stress through its direct measurement. Spatial autocorrelation of the streamwise velocity from the PIV snapshots revealed large scale motions that scale on the order of boundary layer thickness. However, the captured inclination angle was lower than that determined using the classic method by means of wall shear stress and hot-wire anemometry (HWA) temporal cross-correlations and a frozen field hypothesis using a convection velocity. The current study suggests the large size of these motions begins to degrade the applicability of the frozen field hypothesis for the time resolved HWA experiments. The simultaneous PIV and CSSS measurements are also used for spatial reconstruction of the velocity field during conditionally sampled intense wall shear stress events. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship under Grant No. DGE-1315138.

  13. Spinmotive force due to domain wall motion in high field regime

    NASA Astrophysics Data System (ADS)

    Ieda, Jun'ichi; Yamane, Yuta; Maekawa, Sadamichi

    2012-02-01

    Spinmotive force associated with a moving vortex domain wall is investigated numerically. Dynamics of magnetization textures such as a domain wall exerts a non-conservative spin-force on conduction electrons [1], offering a new concept of magnetic devices [2]. This spinmotive force in permalloy nanowires has been detected by voltage measurement [3] where magnitude of the signal is limited less than 500 nV. Theoretically it is suggested that the spinmotive force signal increases as a function of external magnetic fields. At higher magnetic fields, however, the wall propagation mode becomes rather chaotic involving transformations of the wall structure and it remains to be seen how the spinmotive force appears. Numerical simulations show that the spinmotive force scales with the field even in a field range where the wall motion is no longer associated coherent precession. This feature has been tested in a recent experiment [4]. Further enhancement of the spinmotive force is explored by designing ferromagnetic nanostructures [5] and materials. [1] S. Barnes and S. Maekawa, PRL (2007). [2] S. Barnes, J. Ieda, and S. Maekawa, APL (2006). [3] S. A. Yang et al., PRL (2009). [4] M. Hayashi, J. Ieda et al., submitted. [5] Y. Yamane, J. Ieda et al., APEX (2011).

  14. Association of segmental wall motion abnormalities occurring during hemodialysis with post-dialysis fatigue.

    PubMed

    Dubin, Ruth F; Teerlink, John R; Schiller, Nelson B; Alokozai, Dean; Peralta, Carmen A; Johansen, Kirsten L

    2013-10-01

    Post-dialysis fatigue (PDF) is a common, debilitating symptom that remains poorly understood. Cardiac wall motion abnormalities (WMAs) may worsen during dialysis, but it is unknown whether WMA are associated with PDF. Forty patients were recruited from University of California San Francisco-affiliated dialysis units between January 2010 and February 2011. Participants underwent echocardiograms before and during the last hour of 79 dialysis sessions. Myocardial segments were graded 1-4 by a blinded reviewer, with four representing the worst WMA, and the segmental scores were summed for each echocardiogram. Patients completed questionnaires about their symptoms. Severe PDF (defined as lasting >2 h after dialysis) was analysed using a generalized linear model with candidate predictors including anemia, intradialytic hemodynamics and cardiac function. Forty-four percent of patients with worsened WMA (n=9) had severe PDF, compared with 13% of patients with improved or unchanged WMA (P = 0.04). A one-point increase in the WMA score during dialysis was associated with a 10% higher RR of severe PDF [RR: 1.1, 95% CI (1.1, 1.2), P < 0.001]. After multivariable adjustment, every point increase in the WMA score was associated with a 2-fold higher risk of severe PDF [RR: 1.9, 95% CI (1.4, 2.6), P < 0.001]. History of depression was associated with severe PDF after adjustment for demographics and comorbidities [RR: 3.4, 95% CI (1.3, 9), P = 0.01], but anemia, hemodynamics and other parameters of cardiac function were not. Although cross-sectional, these results suggest that some patients may experience severe PDF as a symptom of cardiac ischemia occurring during dialysis.

  15. Simulation of Oscillatory Domain Wall Motion Driven by Spin Waves in Nanostrip with Perpendicular Magnetic Anisotropy

    NASA Astrophysics Data System (ADS)

    Lee, Shang Fan; Chang, Liang Juan; Spintronics Laboratory Team

    2014-03-01

    We numerically investigate the spin waves (SW) induced domain wall (DW) oscillatory motion in a nanostrip with perpendicular magnetic anisotropy by means of micromagnetic simulation. SW carries spin angular momentum and can interact with DWs via Spin Transfer Torque (STT). Propagating SW can drive a DW motion depending on the in-plane tilt angle φ of the wall magnetization. We calculate the instantaneous velocity of DWs as a function of φwith different SW frequency f. We find that the DW motion under propagating SW depends not only on the frequencies f, but also on the in-plane tilt angle φ. The nanostrip considered is 50 nm wide and 4000 nm long. A DW at the center is subjected to a SW source 500 nm apart on the left with amplitude in the transverse direction and varying frequency f. The motions of the DW induced by the SW are accompanied by in-plane rotation of magnetization of DW. Once rotated by 90 degrees, the DW shows a backward motion towards the SW source. The oscillatory amplitude and frequency of the DW motion is analyzed. A phase diagram will be presented. This study provides new perspectives for the control and manipulation of DW in a nanostrip. Financial supports by Academia Sinica and National Science Council are acknowledged

  16. Controlled motion of domain walls in submicron amorphous wires

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ţibu, Mihai; Lostun, Mihaela; Rotărescu, Cristian

    Results on the control of the domain wall displacement in cylindrical Fe{sub 77.5}Si{sub 7.5}B{sub 15} amorphous glass-coated submicron wires prepared by rapid quenching from the melt are reported. The control methods have relied on conical notches with various depths, up to a few tens of nm, made in the glass coating and in the metallic nucleus using a focused ion beam (FIB) system, and on the use of small nucleation coils at one of the sample ends in order to apply magnetic field pulses aimed to enhance the nucleation of reverse domains. The notch-based method is used for the firstmore » time in the case of cylindrical ultrathin wires. The results show that the most efficient technique of controlling the domain wall motion in this type of samples is the simultaneous use of notches and nucleation coils. Their effect depends on wire diameter, notch depth, its position on the wire length, and characteristics of the applied pulse.« less

  17. Quantification of the relative contribution of the different right ventricular wall motion components to right ventricular ejection fraction: the ReVISION method.

    PubMed

    Lakatos, Bálint; Tősér, Zoltán; Tokodi, Márton; Doronina, Alexandra; Kosztin, Annamária; Muraru, Denisa; Badano, Luigi P; Kovács, Attila; Merkely, Béla

    2017-03-27

    Three major mechanisms contribute to right ventricular (RV) pump function: (i) shortening of the longitudinal axis with traction of the tricuspid annulus towards the apex; (ii) inward movement of the RV free wall; (iii) bulging of the interventricular septum into the RV and stretching the free wall over the septum. The relative contribution of the aforementioned mechanisms to RV pump function may change in different pathological conditions.Our aim was to develop a custom method to separately assess the extent of longitudinal, radial and anteroposterior displacement of the RV walls and to quantify their relative contribution to global RV ejection fraction using 3D data sets obtained by echocardiography.Accordingly, we decomposed the movement of the exported RV beutel wall in a vertex based manner. The volumes of the beutels accounting for the RV wall motion in only one direction (either longitudinal, radial, or anteroposterior) were calculated at each time frame using the signed tetrahedron method. Then, the relative contribution of the RV wall motion along the three different directions to global RV ejection fraction was calculated either as the ratio of the given direction's ejection fraction to global ejection fraction and as the frame-by-frame RV volume change (∆V/∆t) along the three motion directions.The ReVISION (Right VentrIcular Separate wall motIon quantificatiON) method may contribute to a better understanding of the pathophysiology of RV mechanical adaptations to different loading conditions and diseases.

  18. Energy-efficient writing scheme for magnetic domain-wall motion memory

    NASA Astrophysics Data System (ADS)

    Kim, Kab-Jin; Yoshimura, Yoko; Ham, Woo Seung; Ernst, Rick; Hirata, Yuushou; Li, Tian; Kim, Sanghoon; Moriyama, Takahiro; Nakatani, Yoshinobu; Ono, Teruo

    2017-04-01

    We present an energy-efficient magnetic domain-writing scheme for domain wall (DW) motion-based memory devices. A cross-shaped nanowire is employed to inject a domain into the nanowire through current-induced DW propagation. The energy required for injecting the magnetic domain is more than one order of magnitude lower than that for the conventional field-based writing scheme. The proposed scheme is beneficial for device miniaturization because the threshold current for DW propagation scales with the device size, which cannot be achieved in the conventional field-based technique.

  19. Oscillatory motion based measurement method and sensor for measuring wall shear stress due to fluid flow

    DOEpatents

    Armstrong, William D [Laramie, WY; Naughton, Jonathan [Laramie, WY; Lindberg, William R [Laramie, WY

    2008-09-02

    A shear stress sensor for measuring fluid wall shear stress on a test surface is provided. The wall shear stress sensor is comprised of an active sensing surface and a sensor body. An elastic mechanism mounted between the active sensing surface and the sensor body allows movement between the active sensing surface and the sensor body. A driving mechanism forces the shear stress sensor to oscillate. A measuring mechanism measures displacement of the active sensing surface relative to the sensor body. The sensor may be operated under periodic excitation where changes in the nature of the fluid properties or the fluid flow over the sensor measurably changes the amplitude or phase of the motion of the active sensing surface, or changes the force and power required from a control system in order to maintain constant motion. The device may be operated under non-periodic excitation where changes in the nature of the fluid properties or the fluid flow over the sensor change the transient motion of the active sensor surface or change the force and power required from a control system to maintain a specified transient motion of the active sensor surface.

  20. Observation of hohlraum-wall motion with spectrally selective x-ray imaging at the National Ignition Facility

    NASA Astrophysics Data System (ADS)

    Izumi, N.; Meezan, N. B.; Divol, L.; Hall, G. N.; Barrios, M. A.; Jones, O.; Landen, O. L.; Kroll, J. J.; Vonhof, S. A.; Nikroo, A.; Jaquez, J.; Bailey, C. G.; Hardy, C. M.; Ehrlich, R. B.; Town, R. P. J.; Bradley, D. K.; Hinkel, D. E.; Moody, J. D.

    2016-11-01

    The high fuel capsule compression required for indirect drive inertial confinement fusion requires careful control of the X-ray drive symmetry throughout the laser pulse. When the outer cone beams strike the hohlraum wall, the plasma ablated off the hohlraum wall expands into the hohlraum and can alter both the outer and inner cone beam propagations and hence the X-ray drive symmetry especially at the final stage of the drive pulse. To quantitatively understand the wall motion, we developed a new experimental technique which visualizes the expansion and stagnation of the hohlraum wall plasma. Details of the experiment and the technique of spectrally selective x-ray imaging are discussed.

  1. Observation of hohlraum-wall motion with spectrally selective x-ray imaging at the National Ignition Facility.

    PubMed

    Izumi, N; Meezan, N B; Divol, L; Hall, G N; Barrios, M A; Jones, O; Landen, O L; Kroll, J J; Vonhof, S A; Nikroo, A; Jaquez, J; Bailey, C G; Hardy, C M; Ehrlich, R B; Town, R P J; Bradley, D K; Hinkel, D E; Moody, J D

    2016-11-01

    The high fuel capsule compression required for indirect drive inertial confinement fusion requires careful control of the X-ray drive symmetry throughout the laser pulse. When the outer cone beams strike the hohlraum wall, the plasma ablated off the hohlraum wall expands into the hohlraum and can alter both the outer and inner cone beam propagations and hence the X-ray drive symmetry especially at the final stage of the drive pulse. To quantitatively understand the wall motion, we developed a new experimental technique which visualizes the expansion and stagnation of the hohlraum wall plasma. Details of the experiment and the technique of spectrally selective x-ray imaging are discussed.

  2. The effects of temperature on the lattice barrier for twin wall motion

    NASA Astrophysics Data System (ADS)

    Zreihan, Noam; Faran, Eilon; Shilo, Doron

    2015-07-01

    The sideways motion of twin walls in ferroic materials requires overcoming an intrinsic energy barrier that originates from the periodicity of the crystal structure. Here, we measure the temperature dependence of the lattice barrier in a ferromagnetic Ni-Mn-Ga crystal using the pulsed magnetic field method. Our results reveal a monotonic decrease in the lattice barrier with increasing temperature. Yet, the barrier does not vanish as the temperature approaches the temperature of the martensite to austenite transformation. These findings enable the formulation of an analytical expression that correlates the lattice barrier to the physical properties of the twin wall, such as its thickness and the associated transformation strain. The derived relation provides a good quantitative description of the data measured in Ni-Mn-Ga.

  3. Observation of hohlraum-wall motion with spectrally selective x-ray imaging at the National Ignition Facility

    DOE PAGES

    Izumi, N.; Meezan, N. B.; Divol, L.; ...

    2016-08-12

    The high fuel capsule compression required for indirect drive inertial confinement fusion (ICF) requires careful control of the X-raydrive symmetry throughout the laser pulse. When the outer cone beams strike the hohlraum wall, the plasma ablated off the hohlraum wall expands into the hohlraum and can alter both the outer and inner cone beam propagation and hencethe X-raydrive symmetry especially at thefinal stage of the drive pulse. In order to quantitatively understand the wall motion, we developed a new experimental technique which visualizes the expansion and stagnation of the hohlraum wall plasma. Finally, we discuss details of the experiment andmore » the technique of spectrally selectivex-ray imaging.« less

  4. Observation of hohlraum-wall motion with spectrally selective x-ray imaging at the National Ignition Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Izumi, N., E-mail: izumi2@llnl.gov; Meezan, N. B.; Divol, L.

    The high fuel capsule compression required for indirect drive inertial confinement fusion requires careful control of the X-ray drive symmetry throughout the laser pulse. When the outer cone beams strike the hohlraum wall, the plasma ablated off the hohlraum wall expands into the hohlraum and can alter both the outer and inner cone beam propagations and hence the X-ray drive symmetry especially at the final stage of the drive pulse. To quantitatively understand the wall motion, we developed a new experimental technique which visualizes the expansion and stagnation of the hohlraum wall plasma. Details of the experiment and the techniquemore » of spectrally selective x-ray imaging are discussed.« less

  5. Observation of hohlraum-wall motion with spectrally selective x-ray imaging at the National Ignition Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Izumi, N.; Meezan, N. B.; Divol, L.

    The high fuel capsule compression required for indirect drive inertial confinement fusion (ICF) requires careful control of the X-raydrive symmetry throughout the laser pulse. When the outer cone beams strike the hohlraum wall, the plasma ablated off the hohlraum wall expands into the hohlraum and can alter both the outer and inner cone beam propagation and hencethe X-raydrive symmetry especially at thefinal stage of the drive pulse. In order to quantitatively understand the wall motion, we developed a new experimental technique which visualizes the expansion and stagnation of the hohlraum wall plasma. Finally, we discuss details of the experiment andmore » the technique of spectrally selectivex-ray imaging.« less

  6. Effect of spin transfer torque on domain wall motion regimes in [Co/Ni] superlattice wires

    NASA Astrophysics Data System (ADS)

    Le Gall, S.; Vernier, N.; Montaigne, F.; Thiaville, A.; Sampaio, J.; Ravelosona, D.; Mangin, S.; Andrieu, S.; Hauet, T.

    2017-05-01

    The combined effect of magnetic field and current on domain wall motion is investigated in epitaxial [Co/Ni] microwires. Both thermally activated and flow regimes are found to be strongly affected by current. All experimental data can be understood by taking into account both adiabatic and nonadiabatic components of the spin transfer torque, the parameters of which are extracted. In the precessional flow regime, it is shown that the domain wall can move in the electron flow direction against a strong applied field, as previously observed. In addition, for a large range of applied magnetic field and injected current, a stochastic domain wall displacement after each pulse is observed. Two-dimensional micromagnetic simulations, including some disorder, show a random fluctuation of the domain wall position that qualitatively matches the experimental results.

  7. Concordance of Motion Sensor and Clinician-Rated Fall Risk Scores in Older Adults.

    PubMed

    Elledge, Julie

    2017-12-01

    As the older adult population in the United States continues to grow, developing reliable, valid, and practical methods for identifying fall risk is a high priority. Falls are prevalent in older adults and contribute significantly to morbidity and mortality rates and rising health costs. Identifying at-risk older adults and intervening in a timely manner can reduce falls. Conventional fall risk assessment tools require a health professional trained in the use of each tool for administration and interpretation. Motion sensor technology, which uses three-dimensional cameras to measure patient movements, is promising for assessing older adults' fall risk because it could eliminate or reduce the need for provider oversight. The purpose of this study was to assess the concordance of fall risk scores as measured by a motion sensor device, the OmniVR Virtual Rehabilitation System, with clinician-rated fall risk scores in older adult outpatients undergoing physical rehabilitation. Three standardized fall risk assessments were administered by the OmniVR and by a clinician. Validity of the OmniVR was assessed by measuring the concordance between the two assessment methods. Stability of the OmniVR fall risk ratings was assessed by measuring test-retest reliability. The OmniVR scores showed high concordance with the clinician-rated scores and high stability over time, demonstrating comparability with provider measurements.

  8. [Evaluation of echocardiographic left ventricular wall motion analysis supported by internet picture viewing system].

    PubMed

    Hirano, Yutaka; Ikuta, Shin-Ichiro; Nakano, Manabu; Akiyama, Seita; Nakamura, Hajime; Nasu, Masataka; Saito, Futoshi; Nakagawa, Junichi; Matsuzaki, Masashi; Miyazaki, Shunichi

    2007-02-01

    Assessment of deterioration of regional wall motion by echocardiography is not only subjective but also features difficulties with interobserver agreement. Progress in digital communication technology has made it possible to send video images from a distant location via the Internet. The possibility of evaluating left ventricular wall motion using video images sent via the Internet to distant institutions was evaluated. Twenty-two subjects were randomly selected. Four sets of video images (parasternal long-axis view, parasternal short-axis view, apical four-chamber view, and apical two-chamber view) were taken for one cardiac cycle. The images were sent via the Internet to two institutions (observer C in facility A and observers D and E in facility B) for evaluation. Great care was taken to prevent disclosure of patient information to these observers. Parasternal long-axis images were divided into four segments, and the parasternal short-axis view, apical four-chamber view, and apical two-chamber view were divided into six segments. One of the following assessments, normokinesis, hypokinesis, akinesis, or dyskinesis, was assigned to each segment. The interobserver rates of agreement in judgments between observers C and D, observers C and E, and intraobserver agreement rate (for observer D) were calculated. The rate of interobserver agreement was 85.7% (394/460 segments; Kappa = 0.65) between observers C and D, 76.7% (353/460 segments; Kappa = 0.39) between observers D and E, and 76.3% (351/460 segments; Kappa = 0.36)between observers C and E, and intraobserver agreement was 94.3% (434/460; Kappa = 0.86). Segments of difference judgments between observers C and D were normokinesis-hypokinesis; 62.1%, hypokinesis-akinesis; 33.3%, akinesis-dyskinesis; 3.0%, and normokinesis-akinesis; 1.5%. Wall motion can be evaluated at remote institutions via the Internet.

  9. Current-induced domain wall motion in permalloy nanowires with a rectangular cross-section

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ai, J. H.; Miao, B. F.; Sun, L.

    2011-11-01

    We performed micromagnetic simulations of the current-induced domain wall motion in permalloy nanowires with rectangular cross-section. In the absence of the nonadiabatic spin-transfer term, a threshold current, J{sub c} is required to drive the domain wall moving continuously. We find that J{sub c} is proportional to the maximum cross product of the demagnetization field and magnetization orientation of the domain wall and the domain wall width. With varying both the wire thickness and width, a minimum threshold current in the order of 10{sup 6} A/cm{sup 2} is obtained when the thickness is equivalent to the wire width. With the nonadiabaticmore » spin-transfer term, the calculated domain wall velocity {nu} equals to the adiabatic spin transfer velocity u when the current is far above the Walker limit J{sub w}. Below J{sub w}, {nu}=({beta}/{alpha})u, where {beta} is the nonadiabatic parameter and {alpha} is the damping factor. For different {beta}, we find the Walker limit can be scaled as J{sub w}=({alpha}/{beta}-{alpha})J{sub c}. Our simulations agree well with the one dimensional analytical calculation, suggesting the findings are the general behaviors of the systems in this particular geometry.« less

  10. Steady motion of skyrmions and domains walls under diffusive spin torques

    NASA Astrophysics Data System (ADS)

    Elías, Ricardo Gabriel; Vidal-Silva, Nicolas; Manchon, Aurélien

    2017-03-01

    We explore the role of the spin diffusion of conducting electrons in two-dimensional magnetic textures (domain walls and skyrmions) with spatial variation of the order of the spin precession length λex. The effect of diffusion reflects in four additional torques that are third order in spatial derivatives of magnetization and bilinear in λex and in the nonadiabatic parameter β'. In order to study the dynamics of the solitons when these diffusive torques are present, we derive the Thiele equation in the limit of steady motion and we compare the results with the nondiffusive limit. When considering a homogenous current these torques increase the longitudinal velocity of transverse domain walls of width Δ by a factor (λex/Δ)2(α/3), α being the magnetic damping constant. In the case of single skyrmions with core radius r0these new contributions tend to increase the Magnus effect in an amount proportional to (λex/r0) 2(1 +2 α β') .

  11. Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.

    PubMed

    Garner, Ethan C; Bernard, Remi; Wang, Wenqin; Zhuang, Xiaowei; Rudner, David Z; Mitchison, Tim

    2011-07-08

    Rod-shaped bacteria elongate by the action of cell wall synthesis complexes linked to underlying dynamic MreB filaments. To understand how the movements of these filaments relate to cell wall synthesis, we characterized the dynamics of MreB and the cell wall elongation machinery using high-precision particle tracking in Bacillus subtilis. We found that MreB and the elongation machinery moved circumferentially around the cell, perpendicular to its length, with nearby synthesis complexes and MreB filaments moving independently in both directions. Inhibition of cell wall synthesis by various methods blocked the movement of MreB. Thus, bacteria elongate by the uncoordinated, circumferential movements of synthetic complexes that insert radial hoops of new peptidoglycan during their transit, possibly driving the motion of the underlying MreB filaments.

  12. Light effects in the atomic-motion-induced Ramsey narrowing of dark resonances in wall-coated cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Breschi, E.; Schori, C.; Di Domenico, G.

    2010-12-15

    We report on light shift and broadening in the atomic-motion-induced Ramsey narrowing of dark resonances prepared in alkali-metal vapors contained in wall-coated cells without buffer gas. The atomic-motion-induced Ramsey narrowing is due to the free motion of the polarized atomic spins in and out of the optical interaction region before spin relaxation. As a consequence of this effect, we observe a narrowing of the dark resonance linewidth as well as a reduction of the ground states' light shift when the volume of the interaction region decreases at constant optical intensity. The results can be intuitively interpreted as a dilution ofmore » the intensity effect similar to a pulsed interrogation due to the atomic motion. Finally the influence of this effect on the performance of compact atomic clocks is discussed.« less

  13. Recovery of BMIPP uptake and regional wall motion in insulin resistant patients following angioplasty for acute myocardial infarction.

    PubMed

    Fujino, Takayuki; Ishii, Yoshinao; Takeuchi, Toshiharu; Hirasawa, Kunihiko; Tateda, Kunihiko; Kikuchi, Kenjiro; Hasebe, Naoyuki

    2003-09-01

    The effect of insulin resistance (IR) on the fatty acid metabolism of myocardium, and therefore on the recovery of left ventricular (LV) wall motion, has not been established in patients with acute myocardial infarction (AMI). A total of consecutive 58 non-diabetic AMI patients who had successfully undergone emergency coronary angioplasty were analyzed retrospectively. They were categorized into 2 groups, normal glucose tolerance (NGT) and impaired glucose tolerance (IGT), based on a 75-g oral glucose tolerance test (OGTT). The parameters of OGTT, myocardial scintigraphy (n=58) (thallium-201 (Tl) and iodine-123-beta-methyl-iodophenylpentadecanoic acid (BMIPP)) and left ventriculography (n=24) were compared in the 2 groups after reperfusion (acute phase) and 3-4 weeks after the AMI (chronic phase). The insulin resistance (IR), estimated by the serum concentration of insulin at 120 min (IRI 120') of the OGTT and by the HOMA (the homeostasis model assessment) index, was higher in the IGT group than in NGT group. An inverse correlation was found between the recovery of regional LV wall motion in the ischemic lesion and the IRI 120' and HOMA index. Although the recovery of BMIPP uptake from the acute to the chronic phase was higher in the IGT group, it was only correlated with the degree of IRI 120', not with the HOMA. IR accompanied by IGT can negatively influence the recovery of regional LV wall motion.

  14. Strain-encoded cardiac MRI as an adjunct for dobutamine stress testing: incremental value to conventional wall motion analysis.

    PubMed

    Korosoglou, Grigorios; Lossnitzer, Dirk; Schellberg, Dieter; Lewien, Antje; Wochele, Angela; Schaeufele, Tim; Neizel, Mirja; Steen, Henning; Giannitsis, Evangelos; Katus, Hugo A; Osman, Nael F

    2009-03-01

    High-dose dobutamine stress MRI is safe and feasible for the diagnosis of coronary artery disease (CAD) in humans. However, the assessment of cine scans relies on the visual interpretation of regional wall motion, which is subjective. Recently, strain-encoded MRI (SENC) has been proposed for the direct color-coded visualization of myocardial strain. The purpose of our study was to compare the diagnostic value of SENC with that provided by conventional wall motion analysis for the detection of inducible ischemia during dobutamine stress MRI. Stress-induced ischemia was assessed by wall motion analysis and by SENC in 101 patients with suspected or known CAD and in 17 healthy volunteers who underwent dobutamine stress MRI in a clinical 1.5-T scanner. Quantitative coronary angiography deemed as the standard reference for the presence or absence of significant CAD (> or =50% diameter stenosis). On a coronary vessel level, SENC detected inducible ischemia in 86 of 101 versus 71 of 101 diseased coronary vessels (P<0.01 versus cine) and showed normal strain response in 189 of 202 versus 194 of 202 vessels with <50% stenosis (P=NS versus cine). On a patient level, SENC detected inducible ischemia in 63 of 64 versus 55 of 64 patients with CAD (P<0.05 versus cine) and showed normal strain response in 32 of 37 versus 34 of 37 patients without CAD (P=NS versus cine). Quantification analysis demonstrated a significant correlation between strain rate reserve and coronary artery stenosis severity (r(2)=0.56, P<0.001), and a cutoff value of strain rate reserve of 1.64 was deemed as a highly accurate marker for the detection of > or =50% stenosis (area under the curve, 0.96; SE, 0.01; 95% CI, 0.94 to 0.98; P<0.001). The direct color-coded visualization of strain on MR images is a useful adjunct for dobutamine stress MRI, which provides incremental value for the detection of CAD compared with conventional wall motion readings on cine images.

  15. Role of spin diffusion in current-induced domain wall motion for disordered ferromagnets

    NASA Astrophysics Data System (ADS)

    Akosa, Collins Ashu; Kim, Won-Seok; Bisig, André; Kläui, Mathias; Lee, Kyung-Jin; Manchon, Aurélien

    2015-03-01

    Current-induced spin transfer torque and magnetization dynamics in the presence of spin diffusion in disordered magnetic textures is studied theoretically. We demonstrate using tight-binding calculations that weak, spin-conserving impurity scattering dramatically enhances the nonadiabaticity. To further explore this mechanism, a phenomenological drift-diffusion model for incoherent spin transport is investigated. We show that incoherent spin diffusion indeed produces an additional spatially dependent torque of the form ˜∇2[m ×(u .∇ ) m ] +ξ ∇2[(u .∇ ) m ] , where m is the local magnetization direction, u is the direction of injected current, and ξ is a parameter characterizing the spin dynamics (precession, dephasing, and spin-flip). This torque, which scales as the inverse square of the domain wall width, only weakly enhances the longitudinal velocity of a transverse domain wall but significantly enhances the transverse velocity of vortex walls. The spatial-dependent spin transfer torque uncovered in this study is expected to have significant impact on the current-driven motion of abrupt two-dimensional textures such as vortices, skyrmions, and merons.

  16. Use of injectable promethazine to decrease symptom scores of Space Motion Sickness

    NASA Technical Reports Server (NTRS)

    Beck, B. G.; Nicogossian, A. E.

    1992-01-01

    Space motion sickness (SMS) has been a problem affecting approximately 74 percent of first time shuttle flyers. Promethazine injections have been used for 29 cases of SMS to decrease the severity of their illness. Although reported to be effective in reducing symptoms in 27 of the 29 cases, there has been no proof of its efficacy. Methods: Retrospective analysis of medical debriefs examining the symptom scores for nausea, vomiting, decreased appetite, and stomach awareness were performed. Each symptom is rated on a mild = 1, moderate = 2, severe = 3 system for each flight day. Crewmember scores for the first three flight days on an initial flight in which injectable promethazine had not been used were compared to scores in a later flight in which the promethazine was utilized. Scores were also compared in a similar group of crewmembers who did not use promethazine. Results: There was a decrease in median scores for all symptoms except nausea, however, it was significant (p = 0.14) only for the vomiting scores. This significant decrease was not seen in the control group. Conclusions: Injectable promethazine has been associated with a significant decrease in vomiting compared to earlier flights in which injectable promethazine was not used.

  17. Simultaneous Assessment of Myocardial Perfusion, Wall Motion, and Deformation during Myocardial Contrast Echocardiography: A Feasibility Study.

    PubMed

    Zoppellaro, Giacomo; Venneri, Lucia; Khattar, Rajdeep S; Li, Wei; Senior, Roxy

    2016-06-01

    Ultrasound contrast agents may be used for the assessment of regional wall motion and myocardial perfusion, but are generally considered not suitable for deformation analysis. The aim of our study was to assess the feasibility of deformation imaging on contrast-enhanced images using a novel methodology. We prospectively enrolled 40 patients who underwent stress echocardiography with continuous intravenous infusion of SonoVue for the assessment of myocardial perfusion imaging with flash replenishment technique. We compared longitudinal strain (Lε) values, assessed with a vendor-independent software (2D CPA), on 68 resting contrast-enhanced and 68 resting noncontrast recordings. Strain analysis on contrast recordings was evaluated in the first cardiac cycles after the flash. Tracking of contrast images was deemed feasible in all subjects and in all views. Contrast administration improved image quality and increased the number of segments used for deformation analysis. Lε of noncontrast and contrast-enhanced images were statistically different (-18.8 ± 4.5% and -22.8 ± 5.4%, respectively; P < 0.001), but their correlation was good (ICC 0.65, 95%CI 0.42-0.78). Patients with resting wall-motion abnormalities showed lower Lε values on contrast recordings (-18.6 ± 6.0% vs. -24.2 ± 5.5%, respectively; P < 0.01). Intra-operator and inter-operator reproducibility was good for both noncontrast and contrast images with no statistical differences. Our study shows that deformation analysis on postflash contrast-enhanced images is feasible and reproducible. Therefore, it would be possible to perform a simultaneous evaluation of wall-motion abnormalities, volumes, ejection fraction, perfusion defects, and cardiac deformation on the same contrast recording. © 2016, Wiley Periodicals, Inc.

  18. Subclinical and clinical correlates of left ventricular wall motion abnormalities in the community.

    PubMed

    Tsao, Connie W; Gona, Philimon; Salton, Carol; Danias, Peter G; Blease, Susan; Hoffmann, Udo; Fox, Caroline S; Albert, Mark; Levy, Daniel; O'Donnell, Christopher J; Manning, Warren J; Yeon, Susan B

    2011-03-15

    The prevalence and clinical correlates of left ventricular (LV) wall motion abnormalities (WMAs), associated with morbidity and mortality, have not been well-characterized in the population. Framingham Heart Study Offspring Cohort participants (n = 1,794, 844 men, age 65 ± 9 years) underwent cine cardiovascular magnetic resonance for evaluation of LV function. A subset (n = 1,009, 460 men) underwent cardiac multidetector computed tomography for analysis of coronary artery calcium. The presence of coronary heart disease and heart failure (CHD-HF) were assessed in relation to the presence of WMAs. WMAs were present in 117 participants (6.5%) and were associated with male gender, elevated hemoglobin A1c, LV mass, LV end-diastolic volume, and lower LV ejection fraction. Of the 1,637 participants without CHD-HF, 68 (4.2%) had WMAs. In this group, WMAs were associated with obesity, hypertension, and Framingham coronary heart disease risk score in the age- and gender-adjusted analyses and were associated with male gender and hypertension on multivariate analysis. Most subjects with WMAs were in the greatest coronary artery calcium groups. The presence of coronary artery calcium greater than the seventy-fifth percentile and Agatston score >100 were associated with a greater than twofold risk of WMAs in the age- and gender-adjusted analysis but were no longer significant when additionally adjusted for CHD-HF. Previous Q-wave myocardial infarction was present in 29% of the 117 participants with WMAs. In conclusion, in the present longitudinally followed free-living population, 4.2% of the participants without CHD-HF had WMAs. WMAs were associated with the clinical parameters associated with cardiovascular disease risk. Aggressive risk factor modification may be prudent for subjects with WMAs, particularly those free of clinical CHD-HF. Copyright © 2011 Elsevier Inc. All rights reserved.

  19. Highly efficient nonrigid motion‐corrected 3D whole‐heart coronary vessel wall imaging

    PubMed Central

    Atkinson, David; Henningsson, Markus; Botnar, Rene M.; Prieto, Claudia

    2016-01-01

    Purpose To develop a respiratory motion correction framework to accelerate free‐breathing three‐dimensional (3D) whole‐heart coronary lumen and coronary vessel wall MRI. Methods We developed a 3D flow‐independent approach for vessel wall imaging based on the subtraction of data with and without T2‐preparation prepulses acquired interleaved with image navigators. The proposed method corrects both datasets to the same respiratory position using beat‐to‐beat translation and bin‐to‐bin nonrigid corrections, producing coregistered, motion‐corrected coronary lumen and coronary vessel wall images. The proposed method was studied in 10 healthy subjects and was compared with beat‐to‐beat translational correction (TC) and no motion correction for the left and right coronary arteries. Additionally, the coronary lumen images were compared with a 6‐mm diaphragmatic navigator gated and tracked scan. Results No significant differences (P > 0.01) were found between the proposed method and the gated and tracked scan for coronary lumen, despite an average improvement in scan efficiency to 96% from 59%. Significant differences (P < 0.01) were found in right coronary artery vessel wall thickness, right coronary artery vessel wall sharpness, and vessel wall visual score between the proposed method and TC. Conclusion The feasibility of a highly efficient motion correction framework for simultaneous whole‐heart coronary lumen and vessel wall has been demonstrated. Magn Reson Med 77:1894–1908, 2017. © 2016 International Society for Magnetic Resonance in Medicine PMID:27221073

  20. Prognostic value of high-dose dobutamine stress magnetic resonance imaging in 1,493 consecutive patients: assessment of myocardial wall motion and perfusion.

    PubMed

    Korosoglou, Grigorios; Elhmidi, Yacine; Steen, Henning; Schellberg, Dieter; Riedle, Nina; Ahrens, Johannes; Lehrke, Stephanie; Merten, Constanze; Lossnitzer, Dirk; Radeleff, Jannis; Zugck, Christian; Giannitsis, Evangelos; Katus, Hugo A

    2010-10-05

    This study sought to determine the prognostic value of wall motion and perfusion assessment during high-dose dobutamine stress (DS) cardiac magnetic resonance imaging (MRI) in a large patient cohort. DS-MRI offers the possibility to integrate myocardial perfusion and wall motion analysis in a single examination for the detection of coronary artery disease (CAD). A total of 1,493 consecutive patients with suspected or known CAD underwent DS-MRI, using a standard protocol in a 1.5-T magnetic resonance scanner. Wall motion and perfusion were assessed at baseline and during stress, and outcome data including cardiac death, nonfatal myocardial infarction ("hard events"), and "late" revascularization performed >90 days after the MR scans were collected during a 2 ± 1 year follow-up period. Fifty-three hard events, including 14 cardiac deaths and 39 nonfatal infarctions, occurred during the follow-up period, whereas 85 patients underwent "late" revascularization. Using multivariable regression analysis, an abnormal result for wall motion or perfusion during stress yielded the strongest independent prognostic value for both hard events and late revascularization, clearly surpassing that of clinical and baseline magnetic resonance parameters (for wall motion: adjusted hazard ratio [HR] of 5.9 [95% confidence interval (CI): 2.5 to 13.6] for hard events and of 3.1 [95% CI: 1.7 to 5.6] for late revascularization, and for perfusion: adjusted HR of 5.4 [95% CI: 2.3 to 12.9] for hard events and of 6.2 [95% CI: 3.3 to 11.3] for late revascularization, p < 0.001 for all). DS-MRI can accurately identify patients who are at increased risk for cardiac death and myocardial infarction, separating them from those with normal findings, who have very low risk for future cardiac events. (Prognostic Value of High Dose Dobutamine Stress Magnetic Resonance Imaging; NCT00837005). Copyright © 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  1. Comparison between spin-orbit torques measured by domain-wall motions and harmonic measurements

    NASA Astrophysics Data System (ADS)

    Kim, Joo-Sung; Nam, Yune-Seok; Kim, Dae-Yun; Park, Yong-Keun; Park, Min-Ho; Choe, Sug-Bong

    2018-05-01

    Here we report the comparison of the spin torque efficiencies measured by three different experimental schemes for Pt/Co/X stacks with material X (= Pt, Ta, Ti, Al, Au, Pd, and Ru. 7 materials). The first two spin torque efficiencies ɛDW (1 ) and ɛDW (2 ) are quantified by the measurement of spin-torque-induced effective field for domain-wall depinning and creeping motions, respectively. The last one—longitudinal spin torque efficiency ɛL—is measured by harmonic signal measurement of the magnetization rotation with uniform magnetization configuration. The results confirm that, for all measured Pt/Co/X stacks, ɛDW (1 ) and ɛDW (2 ) are exactly consistent to each other and these two efficiencies are roughly proportional to ɛL with proportionality constant π/2, which comes from the integration over the domain-wall configuration.

  2. Comparison of method using phase-sensitive motion estimator with speckle tracking method and application to measurement of arterial wall motion

    NASA Astrophysics Data System (ADS)

    Miyajo, Akira; Hasegawa, Hideyuki

    2018-07-01

    At present, the speckle tracking method is widely used as a two- or three-dimensional (2D or 3D) motion estimator for the measurement of cardiovascular dynamics. However, this method requires high-level interpolation of a function, which evaluates the similarity between ultrasonic echo signals in two frames, to estimate a subsample small displacement in high-frame-rate ultrasound, which results in a high computational cost. To overcome this problem, a 2D motion estimator using the 2D Fourier transform, which does not require any interpolation process, was proposed by our group. In this study, we compared the accuracies of the speckle tracking method and our method using a 2D motion estimator, and applied the proposed method to the measurement of motion of a human carotid arterial wall. The bias error and standard deviation in the lateral velocity estimates obtained by the proposed method were 0.048 and 0.282 mm/s, respectively, which were significantly better than those (‑0.366 and 1.169 mm/s) obtained by the speckle tracking method. The calculation time of the proposed phase-sensitive method was 97% shorter than the speckle tracking method. Furthermore, the in vivo experimental results showed that a characteristic change in velocity around the carotid bifurcation could be detected by the proposed method.

  3. Domain wall and interphase boundary motion in (1-x)Bi(Mg 0.5 Ti 0.5 )O 3 –xPbTiO 3 near the morphotropic phase boundary

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tutuncu, Goknur; Chen, Jun; Fan, Longlong

    Electric field-induced changes in the domain wall motion of (1-x)Bi(Mg 0.5Ti 0.5)O 3–xPbTiO 3 (BMT-xPT) near the morphotropic phase boundary (MPB) where x = 0.37 (BMT-37PT) and x =0.38 (BMT-38PT), are studied by means of synchrotron x-ray diffraction. Through Rietveld analysis and profile fitting, a mixture of coexisting monoclinic (Cm) and tetragonal (P4mm) phases is identified at room temperature. Extrinsic contributions to the property coefficients are evident from electric-field-induced domain wall motion in both the tetragonal and monoclinic phases, as well as through the interphase boundary motion between the two phases. Domain wall motion in the tetragonal and monoclinic phasesmore » for BMT-37PT is larger than that of BMT-38PT, possibly due to this composition's closer proximity to the MPB. Increased interphase boundary motion was also observed in BMT-37PT. Lattice strain, which is a function of both intrinsic piezoelectric strain and elastic interactions of the grains (the latter originating from domain wall and interphase boundary motion), is similar for the respective tetragonal and monoclinic phases.« less

  4. Changes in dynamic embryonic heart wall motion in response to outflow tract banding measured using video densitometry

    NASA Astrophysics Data System (ADS)

    Stovall, Stephanie; Midgett, Madeline; Thornburg, Kent; Rugonyi, Sandra

    2016-11-01

    Abnormal blood flow during early cardiovascular development has been identified as a key factor in the pathogenesis of congenital heart disease; however, the mechanisms by which altered hemodynamics induce cardiac malformations are poorly understood. This study used outflow tract (OFT) banding to model increased afterload, pressure, and blood flow velocities at tubular stages of heart development and characterized the immediate changes in cardiac wall motion due to banding in chicken embryo models with light microscopy-based video densitometry. Optical videos were used to acquire two-dimensional heart image sequences over the cardiac cycle, from which intensity data were extracted along the heart centerline at several locations in the heart ventricle and OFT. While no changes were observed in the synchronous contraction of the ventricle with banding, the peristaltic-like wall motion in the OFT was significantly affected. Our data provide valuable insight into early cardiac biomechanics and its characterization using a simple light microscopy-based imaging modality.

  5. Prior Radiotherapy Does Not Affect Abdominal Wall Reconstruction Outcomes: Evidence from Propensity Score Analysis.

    PubMed

    Giordano, Salvatore; Garvey, Patrick B; Baumann, Donald P; Liu, Jun; Butler, Charles E

    2017-03-01

    Prior abdominal wall radiotherapy (XRT) adversely affects wound healing, but data are limited on how prior XRT may affect abdominal wall reconstruction (AWR) outcomes. The purpose of this study was to determine whether prior abdominal wall radiotherapy is associated with a higher incidence of complications following AWR for a hernia or oncologic resection defect. We performed a retrospective study of consecutive patients who underwent complex AWR using acellular dermal matrix (ADM) at a single center. We compared outcomes between patients who underwent prior XRT that directly involved the abdominal wall and those who did not receive XRT. Propensity score match-paired and multivariate analyses were performed. A total of 511 patients (130 [25.4 %] with prior XRT; 381 [74.6 %] without prior XRT) underwent AWR with ADM for repair of a complex hernia or oncologic resection defect. Mean follow-up was 31.4 months, mean XRT dose was 48.9 Gy, and mean time between XRT and reconstruction was 19.2 months. XRT AWR patients underwent more flap reconstructions (14.6 vs. 5.0 %, P < 0.001) but fewer component separations (61.5 vs. 71.4 %; P = 0.036) than non-XRT AWR patients. The two groups had similar rates of hernia recurrence (8.5 vs. 9.4 %; P = 0.737) and surgical site occurrence (25.4 vs. 23.4 %; P = 0.640). In the propensity score-matched subgroups, there were no differences in hernia recurrence, surgical site occurrence, and wound healing complication rates. Prior XRT does not adversely affect outcomes in AWR. However, surgeons should be aware of the higher likelihood of needing a soft tissue flap reconstruction for soft tissue replacement when performing AWR after XRT.

  6. Magnetic guidance versus manual control: comparison of radiofrequency lesion dimensions and evaluation of the effect of heart wall motion in a myocardial phantom.

    PubMed

    Bhaskaran, Abhishek; Barry, M A Tony; Al Raisi, Sara I; Chik, William; Nguyen, Doan Trang; Pouliopoulos, Jim; Nalliah, Chrishan; Hendricks, Roger; Thomas, Stuart; McEwan, Alistair L; Kovoor, Pramesh; Thiagalingam, Aravinda

    2015-10-01

    Magnetic navigation system (MNS) ablation was suspected to be less effective and unstable in highly mobile cardiac regions compared to radiofrequency (RF) ablations with manual control (MC). The aim of the study was to compare the (1) lesion size and (2) stability of MNS versus MC during irrigated RF ablation with and without simulated mechanical heart wall motion. In a previously validated myocardial phantom, the performance of Navistar RMT Thermocool catheter (Biosense Webster, CA, USA) guided with MNS was compared to manually controlled Navistar irrigated Thermocool catheter (Biosense Webster, CA, USA). The lesion dimensions were compared with the catheter in inferior and superior orientation, with and without 6-mm simulated wall motion. All ablations were performed with 40 W power and 30 ml/ min irrigation for 60 s. A total of 60 ablations were performed. The mean lesion volumes with MNS and MC were 57.5 ± 7.1 and 58.1 ± 7.1 mm(3), respectively, in the inferior catheter orientation (n = 23, p = 0.6), 62.8 ± 9.9 and 64.6 ± 7.6 mm(3), respectively, in the superior catheter orientation (n = 16, p = 0.9). With 6-mm simulated wall motion, the mean lesion volumes with MNS and MC were 60.2 ± 2.7 and 42.8 ± 8.4 mm(3), respectively, in the inferior catheter orientation (n = 11, p = <0.01*), 74.1 ± 5.8 and 54.2 ± 3.7 mm(3), respectively, in the superior catheter orientation (n = 10, p = <0.01*). During 6-mm simulated wall motion, the MC catheter and MNS catheter moved 5.2 ± 0.1 and 0 mm, respectively, in inferior orientation and 5.5 ± 0.1 and 0 mm, respectively, in the superior orientation on the ablation surface. The lesion dimensions were larger with MNS compared to MC in the presence of simulated wall motion, consistent with greater catheter stability. However, similar lesion dimensions were observed in the stationary model.

  7. Effects of aortic root motion on wall stress in the Marfan aorta before and after personalised aortic root support (PEARS) surgery.

    PubMed

    Singh, S D; Xu, X Y; Pepper, J R; Izgi, C; Treasure, T; Mohiaddin, R H

    2016-07-05

    Aortic root motion was previously identified as a risk factor for aortic dissection due to increased longitudinal stresses in the ascending aorta. The aim of this study was to investigate the effects of aortic root motion on wall stress and strain in the ascending aorta and evaluate changes before and after implantation of personalised external aortic root support (PEARS). Finite element (FE) models of the aortic root and thoracic aorta were developed using patient-specific geometries reconstructed from pre- and post-PEARS cardiovascular magnetic resonance (CMR) images in three Marfan patients. The wall and PEARS materials were assumed to be isotropic, incompressible and linearly elastic. A static load on the inner wall corresponding to the patients' pulse pressure was applied. Cardiovascular MR cine images were used to quantify aortic root motion, which was imposed at the aortic root boundary of the FE model, with zero-displacement constraints at the distal ends of the aortic branches and descending aorta. Measurements of the systolic downward motion of the aortic root revealed a significant reduction in the axial displacement in all three patients post-PEARS compared with its pre-PEARS counterparts. Higher longitudinal stresses were observed in the ascending aorta when compared with models without the root motion. Implantation of PEARS reduced the longitudinal stresses in the ascending aorta by up to 52%. In contrast, the circumferential stresses at the interface between the supported and unsupported aorta were increase by up to 82%. However, all peak stresses were less than half the known yield stress for the dilated thoracic aorta. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Strain-Encoded Cardiac Magnetic Resonance Imaging as an Adjunct for Dobutamine Stress Testing. Incremental Value to Conventional Wall Motion Analysis

    PubMed Central

    Korosoglou, Grigorios; Lossnitzer, Dirk; Schellberg, Dieter; Lewien, Antje; Wochele, Angela; Schaeufele, Tim; Neizel, Mirja; Steen, Henning; Giannitsis, Evangelos; Katus, Hugo A.; Osman, Nael F.

    2009-01-01

    Background High-dose dobutamine stress magnetic resonance imaging (DS-MRI) is safe and feasible for the diagnosis of coronary artery disease (CAD) in humans. However, the assessment of cine scans relies on the visual interpretation of regional wall motion, which is subjective. Recently, Strain-Encoded MRI (SENC) has been proposed for the direct color-coded visualization of myocardial strain. The purpose of our study was to compare the diagnostic value of SENC to that provided by conventional wall motion analysis for the detection of inducible ischemia during DS-MRI. Methods and Results Stress induced ischemia was assessed by wall motion analysis and by SENC in 101 patients with suspected or known CAD and in 17 healthy volunteers who underwent DS-MRI in a clinical 1.5T scanner. Quantitative coronary angiography deemed as the standard reference for the presence or absence of significant CAD (≥50% diameter stenosis). On a coronary vessel level, SENC detected inducible ischemia in 86/101 versus 71/101 diseased coronary vessels (p<0.01 versus cine), and showed normal strain response in 189/202 versus 194/202 vessels with <50% stenosis (p=NS versus cine). On a patient level, SENC detected inducible ischemia in 63/64 versus 55/64 patients with CAD (p<0.05 versus cine), and showed normal strain response in 32/37 versus 34/37 patients without CAD (p=NS versus cine).Quantification analysis demonstrated a significant correlation between strain rate reserve (SRreserve) and coronary artery stenosis severity (r²=0.56, p<0.001), and a cut-off value of SRreserve=1.64 deemed as a highly accurate marker for the detection of stenosis≥50% (AUC=0.96, SE=0.01, 95% CI = 0.94–0.98, p<0.001). Conclusions The direct color-coded visualization of strain on MR-images is a useful adjunct for DS-MRI, which provides incremental value for the detection of CAD compared to conventional wall motion readings on cine images. PMID:19808579

  9. Color structured light system of chest wall motion measurement for respiratory volume evaluation

    NASA Astrophysics Data System (ADS)

    Chen, Huijun; Cheng, Yuan; Liu, Dongdong; Zhang, Xiaodong; Zhang, Jue; Que, Chengli; Wang, Guangfa; Fang, Jing

    2010-03-01

    We present a structured light system to dynamically measure human chest wall motion for respiratory volume estimation. Based on a projection of an encoded color pattern and a few active markers attached to the trunk, respiratory volumes are obtained by evaluating the 3-D topographic changes of the chest wall in an anatomically consistent measuring region during respiration. Three measuring setups are established: a single-sided illuminating-recording setup for standing posture, an inclined single-sided setup for supine posture, and a double-sided setup for standing posture. Results are compared with the pneumotachography and show good agreement in volume estimations [correlation coefficient: R>0.99 (P<0.001) for all setups]. The isovolume tests present small variations of the obtained volume during the isovolume maneuver (standard deviation<0.085 L for all setups). After validation by the isovolume test, an investigation of a patient with pleural effusion using the proposed method shows pulmonary functional differences between the diseased and the contralateral sides of the thorax, and subsequent improvement of this imbalance after drainage. These results demonstrate the proposed optical method is capable of not only whole respiratory volume evaluation with high accuracy, but also regional pulmonary function assessment in different chest wall behaviors, with the advantage of whole-field measurement.

  10. Temporal Fourier analysis applied to equilibrium radionuclide cineangiography. Importance in the study of global and regional left ventricular wall motion.

    PubMed

    Cardot, J C; Berthout, P; Verdenet, J; Bidet, A; Faivre, R; Bassand, J P; Bidet, R; Maurat, J P

    1982-01-01

    Regional and global left ventricular wall motion was assessed in 120 patients using radionuclide cineangiography (RCA) and contrast angiography. Functional imaging procedures based on a temporal Fourier analysis of dynamic image sequences were applied to the study of cardiac contractility. Two images were constructed by taking the phase and amplitude values of the first harmonic in the Fourier transform for each pixel. These two images aided in determining the perimeter of the left ventricle to calculate the global ejection fraction. Regional left ventricular wall motion was studied by analyzing the phase value and by examining the distribution histogram of these values. The accuracy of global ejection fraction calculation was improved by the Fourier technique. This technique increased the sensitivity of RCA for determining segmental abnormalities especially in the left anterior oblique view (LAO).

  11. Frequency of Inverted Electrocardiographic T Waves (Cerebral T Waves) in Patients With Acute Strokes and Their Relation to Left Ventricular Wall Motion Abnormalities.

    PubMed

    Stone, Jeremy; Mor-Avi, Victor; Ardelt, Agnieszka; Lang, Roberto M

    2018-01-01

    Transient, symmetric, and deep inverted electrocardiogram (ECG) T waves in the setting of stroke, commonly referred to as cerebral T waves, are rare, and the underlying mechanism is unclear. Our study aimed to test the hypothesis that cerebral T waves are associated with transient cardiac dysfunction. This retrospective study included 800 patients admitted with the primary diagnosis of hemorrhagic or ischemic stroke. ECGs were examined for cerebral T waves, defined as T-wave inversion of ≥5 mm depth in ≥4 contiguous precordial leads. Echocardiograms of those meeting these criteria were examined for the presence of left ventricular (LV) wall motion abnormalities. Follow-up evaluation included both ECG and echocardiogram. Of the 800 patients, 17 had cerebral T waves on ECG (2.1%). All 17 patients had ischemic strokes, of which 11 were in the middle cerebral artery distribution (65%), and 2 were cerebellar (12%), whereas the remaining 4 involved other locations. Follow-up ECG showed resolution of the T-wave changes in all 17 patients. Of these patients, 14 (82%) had normal wall motion, and 3 had transient wall motion abnormalities (18%). Two of these patients had Takotsubo-like cardiomyopathy with apical ballooning, and the third had globally reduced LV function. Coronary angiography showed no significant disease to explain the LV dysfunction. In summary, in our cohort of patients with acute stroke, cerebral T waves were rare and occurred only in ischemic stroke. Eighteen percent of patients with cerebral T waves had significant transient wall motion abnormalities. Patients with stroke with cerebral T waves, especially in those with ischemic strokes, should be assessed for cardiac dysfunction. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Oscillatory dependence of current driven domain wall motion on current pulse length

    NASA Astrophysics Data System (ADS)

    Thomas, Luc

    2007-03-01

    The motion of domain walls (DW) in magnetic nanowires driven by spin torque from spin-polarized current is of considerable interest. Most previous work has considered the effect of dc or ˜microsecond long current pulses. Here, we show that the dynamics of DWs driven by nanosecond-long current pulses is unexpectedly complex. In particular, we show that the current driven motion of a DW, confined to a pinning site in a permalloy nanowire, exhibits an oscillatory dependence on the current pulse length with a period of just a few nanoseconds [1]. This behavior can be understood within a surprisingly straightforward one dimensional analytical model of the DW's motion. When a current pulse is applied, the DW's position oscillates within the pinning potential out of phase with the DW's out-of-plane magnetization, where the latter acts like the DW's momentum. Thus, the current driven motion of the DW is akin to a harmonic oscillator, whose frequency is determined by the ``mass'' of the DW and where the restoring force is related to the slope of the pinning potential. Remarkably, when the current pulse is turned off during phases of the DW motion when it has enough momentum, the amplitude of the oscillations can be amplified such that the DW exits the pinning potential well after the pulse is turned off. This oscillatory depinning occurs for currents smaller than the dc threshold current, and, moreover, the DW moves against the electron flow, opposite to the propagation direction above the dc threshold. These effects can be further amplified by using trains of current pulses whose lengths and separations are matched to the DW's oscillation period. In this way, we have demonstrated a five fold reduction in the threshold current required to move a DW out of a pinning site, making this effect potentially important for technological applications. [1] L. Thomas, M. Hayashi, X. Jiang, R. Moriya, C. Rettner and S.S.P. Parkin, Nature 443, 197 (2006).

  13. Aging near the wall in colloidal glasses

    NASA Astrophysics Data System (ADS)

    Cao, Cong; Huang, Xinru; Weeks, Eric

    In a colloidal glass system, particles move slower as sample ages. In addition, their motions may be affected by their local structure, and this structure will be different near a wall. We examine how the aging process near a wall differs from that in the bulk of the sample. In particular, we use a confocal microscope to observe 3D motion in a bidisperse colloidal glass sample. We find that flat walls induce the particles to organize into layers. The aging process behaves differently near the boundary, especially within the first three layers. Particle motion near the wall is noticeably slower but also changes less dramatically with age. We compare and contrast aging seen in samples with flat and rough walls.

  14. Effects of non-invasive ventilation and posture on chest wall volumes and motion in patients with amyotrophic lateral sclerosis: a case series

    PubMed Central

    Magalhães, Cristiana M.; Fregonezi, Guilherme A.; Vidigal-Lopes, Mauro; Vieira, Bruna S. P. P.; Vieira, Danielle S. R.; Parreira, Verônica F.

    2016-01-01

    ABSTRACT Background The effects of non-invasive ventilation (NIV) on the breathing pattern and thoracoabdominal motion of patients with amyotrophic lateral sclerosis (ALS) are unknown. Objectives 1) To analyze the influence of NIV on chest wall volumes and motion assessed by optoelectronic plethysmography in ALS patients and 2) to compare these parameters in the supine and sitting positions to those of healthy individuals (without NIV). Method Nine ALS patients were evaluated in the supine position using NIV. In addition, the ALS patients and nine healthy individuals were evaluated in both sitting and supine positions. Statistical analysis was performed using the paired Student t-test or Wilcoxon test and the Student t-test for independent samples or Mann-Whitney U test. Results Chest wall volume increased significantly with NIV, mean volume=0.43 (SD=0.16)L versus 0.57 (SD=0.19)L (p=0.04). No significant changes were observed for the pulmonary rib cage, abdominal rib cage, or abdominal contribution. The index of the shortening velocity of the diaphragmatic muscle, mean=0.15 (SD=0.05)L/s versus 0.21 (SD=0.05)L/s (p<0.01), and abdominal muscles, mean=0.09 (SD=0.02)L/s versus 0.14 (SD=0.06)L/s (p<0.01), increased during NIV. Comparisons between the supine and sitting positions showed similar changes in chest wall motion in both groups. However, the ALS patients presented a significantly lower contribution of the abdomen in the supine position compared with the controls, mean=56 (SD=13) versus 69 (SD=10) (p=0.02). Conclusions NIV improved chest wall volumes without changing the contribution of the chest wall compartment in ALS patients. In the supine position, ALS patients had a lower contribution of the abdomen, which may indicate early diaphragmatic dysfunction. PMID:27556390

  15. Effects of non-invasive ventilation and posture on chest wall volumes and motion in patients with amyotrophic lateral sclerosis: a case series.

    PubMed

    Magalhães, Cristiana M; Fregonezi, Guilherme A; Vidigal-Lopes, Mauro; Vieira, Bruna S P P; Vieira, Danielle S R; Parreira, Verônica F

    2016-01-01

    The effects of non-invasive ventilation (NIV) on the breathing pattern and thoracoabdominal motion of patients with amyotrophic lateral sclerosis (ALS) are unknown. 1) To analyze the influence of NIV on chest wall volumes and motion assessed by optoelectronic plethysmography in ALS patients and 2) to compare these parameters in the supine and sitting positions to those of healthy individuals (without NIV). Nine ALS patients were evaluated in the supine position using NIV. In addition, the ALS patients and nine healthy individuals were evaluated in both sitting and supine positions. Statistical analysis was performed using the paired Student t-test or Wilcoxon test and the Student t-test for independent samples or Mann-Whitney U test. Chest wall volume increased significantly with NIV, mean volume=0.43 (SD=0.16)L versus 0.57 (SD=0.19)L (p=0.04). No significant changes were observed for the pulmonary rib cage, abdominal rib cage, or abdominal contribution. The index of the shortening velocity of the diaphragmatic muscle, mean=0.15 (SD=0.05)L/s versus 0.21 (SD=0.05)L/s (p<0.01), and abdominal muscles, mean=0.09 (SD=0.02)L/s versus 0.14 (SD=0.06)L/s (p<0.01), increased during NIV. Comparisons between the supine and sitting positions showed similar changes in chest wall motion in both groups. However, the ALS patients presented a significantly lower contribution of the abdomen in the supine position compared with the controls, mean=56 (SD=13) versus 69 (SD=10) (p=0.02). NIV improved chest wall volumes without changing the contribution of the chest wall compartment in ALS patients. In the supine position, ALS patients had a lower contribution of the abdomen, which may indicate early diaphragmatic dysfunction.

  16. Brownian motion as a new probe of wettability.

    PubMed

    Mo, Jianyong; Simha, Akarsh; Raizen, Mark G

    2017-04-07

    Understanding wettability is crucial for optimizing oil recovery, semiconductor manufacturing, pharmaceutical industry, and electrowetting. In this letter, we study the effects of wettability on Brownian motion. We consider the cases of a sphere in an unbounded fluid medium, as well as a sphere placed in the vicinity of a plane wall. For the first case, we show the effects of wettability on the statistical properties of the particles' motion, such as velocity autocorrelation, velocity, and thermal force power spectra over a large range of time scales. We also propose a new method to measure wettability based on the particles' Brownian motion. In addition, we compare the boundary effects on Brownian motion imposed by both no-slip and perfect-slip flat walls. We emphasize the surprising boundary effects on Brownian motion imposed by a perfect-slip wall in the parallel direction, such as a higher particle mobility parallel to a perfect flat wall compared to that in the absence of the wall, as well as compared to a particle near a no-slip flat wall.

  17. Sci-Fri PM: Radiation Therapy, Planning, Imaging, and Special Techniques - 11: Quantification of chest wall motion during deep inspiration breast hold treatments using cine EPID images and a physics based algorithm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alpuche Aviles, Jorge E.; VanBeek, Timothy

    Purpose: This work presents an algorithm used to quantify intra-fraction motion for patients treated using deep inspiration breath hold (DIBH). The algorithm quantifies the position of the chest wall in breast tangent fields using electronic portal images. Methods: The algorithm assumes that image profiles, taken along a direction perpendicular to the medial border of the field, follow a monotonically and smooth decreasing function. This assumption is invalid in the presence of lung and can be used to calculate chest wall position. The algorithm was validated by determining the position of the chest wall for varying field edge positions in portalmore » images of a thoracic phantom. The algorithm was used to quantify intra-fraction motion in cine images for 7 patients treated with DIBH. Results: Phantom results show that changes in the distance between chest wall and field edge were accurate within 0.1 mm on average. For a fixed field edge, the algorithm calculates the position of the chest wall with a 0.2 mm standard deviation. Intra-fraction motion for DIBH patients was within 1 mm 91.4% of the time and within 1.5 mm 97.9% of the time. The maximum intra-fraction motion was 3.0 mm. Conclusions: A physics based algorithm was developed and can be used to quantify the position of chest wall irradiated in tangent portal images with an accuracy of 0.1 mm and precision of 0.6 mm. Intra-fraction motion for patients treated with DIBH at our clinic is less than 3 mm.« less

  18. Local Nanomechanical Motion In Single Cells.

    NASA Astrophysics Data System (ADS)

    Pelling, Andrew; Gimzewski, James

    2004-03-01

    We present new evidence that the nanoscale motion of the cell wall of Saccharomyces cerevisiae exhibits local bionanomechanical motion at characteristic frequencies and which is not caused by random or Brownian processes. This motion is measured with the AFM tip which acts as a nanomechanical sensor, permitting the motion of the cell wall to be recorded as a function of time, applied force, etc. We present persuasive evidence which shows that the local nanomechanical motion is characteristic of metabolic processes taking place inside the cell. This is demonstrated by clear differences between living cells and living cells treated with a metabolic inhibitor. This inhibitor specifically targets cytochrome oxidase inside the mitochondria and inhibits ATP production. The cells observed in this study display characteristic local cell wall motion with amplitudes between 1 and 3 nm and frequencies between 500 and 1700 Hz. The motion is temperature dependant which also suggests the mechanism for the observed motion has biological origins. In addition to a stringent series of control experiments we also discuss local measurements of the cell's mechanical properties and their influence on the observed bionanomechanical motion.

  19. Two-dimensional simulation of red blood cell motion near a wall under a lateral force

    NASA Astrophysics Data System (ADS)

    Hariprasad, Daniel S.; Secomb, Timothy W.

    2014-11-01

    The motion of a red blood cell suspended in a linear shear flow adjacent to a fixed boundary subject to an applied lateral force directed toward the boundary is simulated. A two-dimensional model is used that represents the viscous and elastic properties of normal red blood cells. Shear rates in the range of 100 to 600 s-1 are considered, and the suspending medium viscosity is 1 cP. In the absence of a lateral force, the cell executes a tumbling motion. With increasing lateral force, a transition from tumbling to tank-treading is predicted. The minimum force required to ensure tank-treading increases nonlinearly with the shear rate. Transient swinging motions occur when the force is slightly larger than the transition value. The applied lateral force is balanced by a hydrodynamic lift force resulting from the positive orientation of the long axis of the cell with respect to the wall. In the case of cyclic tumbling motions, the orientation angle takes positive values through most of the cycle, resulting in lift generation. These results are used to predict the motion of a cell close to the outer edge of the cell-rich core region that is generated when blood flows in a narrow tube. In this case, the lateral force is generated by shear-induced dispersion, resulting from cell-cell interactions in a region with a concentration gradient. This force is estimated using previous data on shear-induced dispersion. The cell is predicted to execute tank-treading motions at normal physiological hematocrit levels, with the possibility of tumbling at lower hematocrit levels.

  20. Respiratory kinematics by optoelectronic analysis of chest-wall motion and ultrasonic imaging of the diaphragm

    NASA Astrophysics Data System (ADS)

    Aliverti, Andrea; Pedotti, Antonio; Ferrigno, Giancarlo; Macklem, P. T.

    1998-07-01

    Although from a respiratory point of view, compartmental volume change or lack of it is the most crucial variable, it has not been possible to measure the volume of chest wall compartments directly. Recently we developed a new method based on a optoelectronic motion analyzer that can give the three-dimensional location of many markers with the temporal and spatial accuracy required for respiratory measurements. Marker's configuration has been designed specifically to measure the volume of three chest wall compartments, the pulmonary and abdominal rib cage compartments and the abdomen, directly. However, it can not track the exact border between the two rib cage compartments (pulmonary and abdominal) which is determined by the cephalic extremity of the area of apposition of the diaphragm to the inner surface of the rib cage, and which can change systematically as a result of disease processes. The diaphragm displacement can be detected by ultrasonography. In the present study, we propose an integrated system able to investigate the relationships between external (chest wall) and internal (diaphragm) movements of the different respiratory structures by simultaneous external imaging with the optoelectronic system combined with internal kinematic imaging using ultrasounds. 2D digitized points belonging to the lower lung margin, taken from ultrasonographic views, are mapped into the 3D space, where chest wall markers are acquired. Results are shown in terms of accuracy of 3D probe location, relative movement between the probe and the body landmarks, dynamic relationships between chest wall volume and position of the diaphragm during quiet breathing, slow inspirations, relaxations and exercise.

  1. Evaluation of left ventricular wall motion and function in patients with previous myocardial infarction by three-dimensional 99mTc-HSAD multigated cardiac pool imaging.

    PubMed

    Yamazaki, J; Naitou, K; Ishida, S; Uno, N; Saisho, K; Munakata, T; Morishita, T; Takano, M; Yabe, Y

    1997-05-01

    To evaluate left ventricular (LV) wall motion stereoscopically from all directions and to calculate the LV volume by three-dimensional (3D) imaging. 99mTc-DTPA human serum albumin-multigated cardiac pool-single photon emission computed tomography (99mTc-MUGA-SPECT) was performed. A new data processing program was developed with the Application Visualization System-Medical Viewer (AVS-MV) based on images obtained from 99mTc-MUGA-SPECT. In patients with previous myocardial infarction, LV function and LV wall motion were evaluated by 3D-99mTc-MUGA imaging. The LV end-diastolic volume (LVEDV) and end-systolic volume (LVESV) were obtained from 3D-99mTc-MUGA images by the surface rendering method, and the left ventricular ejection fraction (LVEF) was calculated at thresholds of 35% (T1), 40% (T2), 45% (T3), and 50% (T4). There was a strong correlation between the LV volume calculated by 3D-99mTc-MUGA imaging at a threshold of 40% and that determined by contrast left ventriculography (LVEDV: 194.7 +/- 36.0 ml vs. 198.7 +/- 39.1 ml, r = 0.791, p < 0.001; LVESV: 91.6 +/- 44.5 ml vs. 93.3 +/- 41.3 ml, r = 0.953, p < 0.001), respectively. When compared with the LVEF data obtained by left ventriculography, significant correlations were found for 3D images reconstructed at each threshold (T1: r = 0.966; T2: r = 0.962; T3: r = 0.958; and T4: r = 0.955). In addition, when LV wall motion obtained by 3D-99mTc-MUGA imaging (LAT and LAO views) was compared with the results obtained by left ventriculography (RAO and LAO views), there was good agreement. 3D-99mTc-MUGA imaging was superior in allowing evaluation of LV wall motion in all directions and in assessment of LV function, since data acquisition and image reconstruction could be done within a short time with the three-detector imaging system and AVS-MV. This method appears to be very useful for the observation of both LV wall motion and LV function in patients with ischemic heart disease, because it is a noninvasive examination.

  2. Comparison of Quantitative Wall Motion Analysis and Strain For Detection Of Coronary Stenosis With Three-Dimensional Dobutamine Stress Echocardiography

    PubMed Central

    Parker, Katherine M.; Clark, Alexander P.; Goodman, Norman C.; Glover, David K.; Holmes, Jeffrey W.

    2015-01-01

    Background Quantitative analysis of wall motion from three-dimensional (3D) dobutamine stress echocardiography (DSE) could provide additional diagnostic information not available from qualitative analysis. In this study we compare the effectiveness of 3D fractional shortening (3DFS), a measure of wall motion computed from 3D echocardiography (3DE), to strain and strain rate measured with sonomicrometry for detecting critical stenoses during DSE. Methods Eleven open-chest dogs underwent DSE both with and without a critical stenosis. 3DFS was measured from 3DE images acquired at peak stress. 3DFS was normalized by subtracting average 3DFS during control peak stress (Δ3DFS). Strains in the perfusion defect (PD) were measured from sonomicrometry, and PD size and location were measured with microspheres. Results A Δ3DFS abnormality indicated the presence of a critical stenosis with high sensitivity and specificity (88% and 100%, respectively), and Δ3DFS abnormality size correlated with PD size (R2=0.54). The sensitivity and specificity for Δ3DFS was similar to that for area strain (88%, 100%) and circumferential strain and strain rate (88%, 92% and 88%, 86%, respectively), while longitudinal strain and strain rate were less specific. Δ3DFS correlated significantly with both coronary flow reserve (R2=0.71) and PD size (R2=0.97), while area strain correlated with PD size only (R2=0.67), and other measures were not significantly correlated with flow reserve or PD size. Conclusion Quantitative wall motion analysis using Δ3DFS is effective for detecting critical stenoses during DSE, performing similarly to 3D strain, and provides potentially useful information on the size and location of a perfusion defect. PMID:24815588

  3. Distance-from-the-wall scaling of turbulent motions in wall-bounded flows

    NASA Astrophysics Data System (ADS)

    Baidya, R.; Philip, J.; Hutchins, N.; Monty, J. P.; Marusic, I.

    2017-02-01

    An assessment of self-similarity in the inertial sublayer is presented by considering the wall-normal velocity, in addition to the streamwise velocity component. The novelty of the current work lies in the inclusion of the second velocity component, made possible by carefully conducted subminiature ×-probe experiments to minimise the errors in measuring the wall-normal velocity. We show that not all turbulent stress quantities approach the self-similar asymptotic state at an equal rate as the Reynolds number is increased, with the Reynolds shear stress approaching faster than the streamwise normal stress. These trends are explained by the contributions from attached eddies. Furthermore, the Reynolds shear stress cospectra, through its scaling with the distance from the wall, are used to assess the wall-normal limits where self-similarity applies within the wall-bounded flow. The results are found to be consistent with the recent prediction from the work of Wei et al. ["Properties of the mean momentum balance in turbulent boundary layer, pipe and channel flows," J. Fluid Mech. 522, 303-327 (2005)], Klewicki ["Reynolds number dependence, scaling, and dynamics of turbulent boundary layers," J. Fluids Eng. 132, 094001 (2010)], and others that the self-similar region starts and ends at z+˜O (√{δ+}) and O (δ+) , respectively. Below the self-similar region, empirical evidence suggests that eddies responsible for turbulent stresses begin to exhibit distance-from-the-wall scaling at a fixed z+ location; however, they are distorted by viscous forces, which remain a leading order contribution in the mean momentum balance in the region z+≲O (√{δ+}) , and thus result in a departure from self-similarity.

  4. Current induced domain wall motion and tilting in Pt/Co/Ta structures with perpendicular magnetic anisotropy in the presence of the Dyzaloshinskii–Moriya interaction

    NASA Astrophysics Data System (ADS)

    Yun, Jijun; Li, Dong; Cui, Baoshan; Guo, Xiaobin; Wu, Kai; Zhang, Xu; Wang, Yupei; Mao, Jian; Zuo, Yalu; Xi, Li

    2018-04-01

    Current induced domain wall motion (CIDWM) was studied in Pt/Co/Ta structures with perpendicular magnetic anisotropy and the Dyzaloshinskii–Moriya interaction (DMI) by the spin-orbit torque (SOT). We measured the strength of DMI and SOT efficiency in Pt/Co/Ta with the variation of the thickness of Ta using a current induced hysteresis loop shift method. The results indicate that the DMI stabilizes a chiral Néel-type domain wall (DW), and the DW motion can be driven by the enhanced large SOT generated from Pt and Ta with opposite signs of spin Hall angle in Pt/Co/Ta stacks. The CIDWM velocity, which is 104 times larger than the field driven DW velocity, obeys a creep law, and reaches around tens of meters per second with current density of ~106 A cm‑2. We also found that the Joule heating accompanied with current also accelerates the DW motion. Meanwhile, a domain wall tilting was observed, which increases with current density increasing. These results can be explained by the spin Hall effect generated from both heavy metals Pt and Ta, inherent DMI, and the current accompanying Joule heating effect. Our results could provide some new designing prospects to move multiple DWs by SOT for achieving racetrack memories.

  5. Domain wall and interphase boundary motion in (1−x)Bi(Mg{sub 0.5}Ti{sub 0.5})O{sub 3}–xPbTiO{sub 3} near the morphotropic phase boundary

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tutuncu, Goknur; Chen, Jun; Fan, Longlong

    Electric field-induced changes in the domain wall motion of (1−x)Bi(Mg{sub 0.5}Ti{sub 0.5})O{sub 3}–xPbTiO{sub 3} (BMT-xPT) near the morphotropic phase boundary (MPB) where x = 0.37 (BMT-37PT) and x = 0.38 (BMT-38PT), are studied by means of synchrotron x-ray diffraction. Through Rietveld analysis and profile fitting, a mixture of coexisting monoclinic (Cm) and tetragonal (P4mm) phases is identified at room temperature. Extrinsic contributions to the property coefficients are evident from electric-field-induced domain wall motion in both the tetragonal and monoclinic phases, as well as through the interphase boundary motion between the two phases. Domain wall motion in the tetragonal and monoclinic phases for BMT-37PT ismore » larger than that of BMT-38PT, possibly due to this composition's closer proximity to the MPB. Increased interphase boundary motion was also observed in BMT-37PT. Lattice strain, which is a function of both intrinsic piezoelectric strain and elastic interactions of the grains (the latter originating from domain wall and interphase boundary motion), is similar for the respective tetragonal and monoclinic phases.« less

  6. Nonmassive acute pulmonary embolism: evaluation of the impact of pulmonary arterial wall distensibility on the assessment of the CT obstruction score.

    PubMed

    Bigot, Julien; Rémy-Jardin, Martine; Duhamel, Alain; Gorgos, Andréi-Bogdan; Faivre, Jean-Baptiste; Rémy, Jacques

    2010-02-01

    To evaluate the impact of pulmonary arterial wall distensibility on the assessment of a computed tomography (CT) score in patients with nonmassive pulmonary embolism (PE) (ie, Mastora score). The arterial wall distensibility of five central pulmonary arteries (pulmonary artery trunk, right and left main pulmonary arteries, right and left interlobar pulmonary arteries) was studied on ECG-gated CT angiographic studies of the chest in 15 patients with no pulmonary arterial hypertension (group 1; mean pulmonary artery pressure: 17.2 mm Hg) and 9 patients with nonmassive PE (group 2), using 2D reconstructions at every 10% of the R-R interval. The systolic and diastolic reconstruction time windows of the examined arteries were identical in the 2 groups, obtained at 20% and 80% of the R-R interval, respectively. No statistically significant difference was observed between the mean values of the pulmonary arterial wall distensibility between the 2 groups, varying between 20.5% and 24% in group 1 and between 23.3% and 25.9% in group 2. The coefficients of variation of the average arterial surfaces were found to vary between 4.30% and 6.50% in group 1 and 4.2% and 8.4% in group 2. Except the pulmonary artery trunk in group 2, all the intraclass correlation coefficients were around 0.8 or greater than 0.8, that is the cutoff for good homogeneity of measurements. The pulmonary arterial wall systolic-diastolic distensibility does not interfere with the assessment of a CT obstruction score in the setting of nonmassive PE.

  7. Automated classification of LV regional wall motion based on spatio-temporal profiles from cardiac cine magnetic resonance imaging

    NASA Astrophysics Data System (ADS)

    Mantilla, Juan; Garreau, Mireille; Bellanger, Jean-Jacques; Paredes, José Luis

    2013-11-01

    Assessment of the cardiac Left Ventricle (LV) wall motion is generally based on visual inspection or quantitative analysis of 2D+t sequences acquired in short-axis cardiac cine-Magnetic Resonance Imaging (MRI). Most often, cardiac dynamic is globally analized from two particular phases of the cardiac cycle. In this paper, we propose an automated method to classify regional wall motion in LV function based on spatio-temporal pro les and Support Vector Machines (SVM). This approach allows to obtain a binary classi cation between normal and abnormal motion, without the need of pre-processing and by exploiting all the images of the cardiac cycle. In each short- axis MRI slice level (basal, median, and apical), the spatio-temporal pro les are extracted from the selection of a subset of diametrical lines crossing opposites LV segments. Initialized at end-diastole phase, the pro les are concatenated with their corresponding projections into the succesive temporal phases of the cardiac cycle. These pro les are associated to di erent types of information that derive from the image (gray levels), Fourier, Wavelet or Curvelet domains. The approach has been tested on a set of 14 abnormal and 6 healthy patients by using a leave-one-out cross validation and two kernel functions for SVM classi er. The best classi cation performance is yielded by using four-level db4 wavelet transform and SVM with a linear kernel. At each slice level the results provided a classi cation rate of 87.14% in apical level, 95.48% in median level and 93.65% in basal level.

  8. Aortic Wall Extracellular Matrix Proteins Correlate with Syntax Score in Patients Undergoing Coronary Artery Bypass Surgery

    PubMed Central

    Chiong, Terri; Cheow, Esther S. H.; Woo, Chin C.; Lin, Xiao Y.; Khin, Lay W.; Lee, Chuen N.; Hartman, Mikael; Sze, Siu K.; Sorokin, Vitaly A.

    2016-01-01

    Aims: The SYNTAX score correlate with major cardiovascular events post-revascularization, although the histopathological basis is unclear. We aim to evaluate the association between syntax score and extracellular matrix histological characteristics of aortic punch tissue obtained during coronary artery bypass surgery (CABG). This analysis compares coronary artery bypass surgery patients with High and Low syntax score which were followed up for one year period. Methods and Results: Patients with High (score ≥ 33, (n=77)) and Low Syntax Scores (score ≤ 22, (n=71)) undergoing elective CABG were recruited prospectively. Baseline clinical characteristics and surgical risks were well matched. At 1 year, EMACCE (Sum of cardiovascular death, stroke, congestive cardiac failure, and limb, gut and myocardial ischemia) was significantly elevated in the High syntax group (P=0.022). Mass spectrometry (MS)-based quantitative iTRAQ proteomic results validated on independent cohort by immunohistochemistry (IHC) revealed that the High syntax group had significantly upraised Collagen I (P<0.0001) and Elastin (P<0.0001) content in ascending aortic wall. Conclusion: This study shows that aortic extracellular matrix (ECM) differ between High and Low syntax groups with up-regulation of Collagen I and Elastin level in High Syntax Score group. This identifies aortic punches collected during CABG as another biomarker source related with atherosclerosis severity and possible clinical outcome. PMID:27347220

  9. Large-scale influences in near-wall turbulence.

    PubMed

    Hutchins, Nicholas; Marusic, Ivan

    2007-03-15

    Hot-wire data acquired in a high Reynolds number facility are used to illustrate the need for adequate scale separation when considering the coherent structure in wall-bounded turbulence. It is found that a large-scale motion in the log region becomes increasingly comparable in energy to the near-wall cycle as the Reynolds number increases. Through decomposition of fluctuating velocity signals, it is shown that this large-scale motion has a distinct modulating influence on the small-scale energy (akin to amplitude modulation). Reassessment of DNS data, in light of these results, shows similar trends, with the rate and intensity of production due to the near-wall cycle subject to a modulating influence from the largest-scale motions.

  10. The effect of vessel material properties and pulsatile wall motion on the fixation of a proximal stent of an endovascular graft.

    PubMed

    Corbett, T J; Molony, D S; Callanan, A; McGloughlin, T M

    2011-01-01

    Migration is a serious failure mechanism associated with endovascular abdominal aortic aneurysm (AAA) repair (EVAR). The effect of vessel material properties and pulsatile wall motion on stent fixation has not been previously investigated. A proximal stent from a commercially available stent graft was implanted into the proximal neck of silicone rubber abdominal aortic aneurysm models of varying proximal neck stiffness (β=25.39 and 20.44). The stent was then dislodged by placing distal force on the stent struts. The peak force to completely dislodge the stent was measured using a loadcell. Dislodgment was performed at ambient pressure with no flow (NF) and during pulsatile flow (PF) at pressures of 120/80 mmHg and 140/100 mmHg to determine if pulsatile wall motions affected the dislodgement force. An imaging analysis was performed at ambient pressure and at pressures of 120 mmHg and 140 mmHg to investigate diameter changes on the model due to the radial force of the stent and internal pressurisation. Stent displacement forces were ~50% higher in the stiffer model (7.16-8.4 N) than in the more compliant model (3.67-4.21 N). The mean displacement force was significantly reduced by 10.95-12.83% from the case of NF to the case of PF at 120/80 mmHg. A further increase in pressure to 140/120 mmHg had no significant effect on the displacement force. The imaging analysis showed that the diameter in the region of the stent was 0.37 mm greater in the less stiff model at all the pressures which could reduce the fixation of the stent. The results suggest that the fixation of passively fixated aortic stents could be comprised in more compliant walls and that pulsatile motions of the wall can reduce the maximum stent fixation. Copyright © 2010 IPEM. Published by Elsevier Ltd. All rights reserved.

  11. Driving chiral domain walls in antiferromagnets using rotating magnetic fields

    NASA Astrophysics Data System (ADS)

    Pan, Keming; Xing, Lingdi; Yuan, H. Y.; Wang, Weiwei

    2018-05-01

    We show theoretically and numerically that an antiferromagnetic domain wall can be moved by a rotating magnetic field in the presence of Dzyaloshinskii-Moriya interaction (DMI). Two motion modes are found: rigid domain wall motion at low frequency (corresponding to the perfect frequency synchronization) and the oscillating motion at high frequency. In the full synchronized region, the steady velocity of the domain wall is universal, in the sense that it depends only on the frequency of the rotating field and the ratio between DMI strength and exchange constant. The domain wall velocity is independent of the Gilbert damping and the rotating field strength. Moreover, a rotating field in megahertz is sufficient to move the antiferromagnetic domain wall.

  12. Depinning of the transverse domain wall trapped at magnetic impurities patterned in planar nanowires: Control of the wall motion using low-intensity and short-duration current pulses

    NASA Astrophysics Data System (ADS)

    Paixão, E. L. M.; Toscano, D.; Gomes, J. C. S.; Monteiro, M. G.; Sato, F.; Leonel, S. A.; Coura, P. Z.

    2018-04-01

    Understanding and controlling of domain wall motion in magnetic nanowires is extremely important for the development and production of many spintronic devices. It is well known that notches are able to pin domain walls, but their pinning potential strength are too strong and it demands high-intensity current pulses to achieve wall depinning in magnetic nanowires. However, traps of pinning can be also originated from magnetic impurities, consisting of located variations of the nanowire's magnetic properties, such as exchange stiffness constant, saturation magnetization, anisotropy constant, damping parameter, and so on. In this work, we have performed micromagnetic simulations to investigate the depinning mechanism of a transverse domain wall (TDW) trapped at an artificial magnetic defect using spin-polarized current pulses. In order to create pinning traps, a simplified magnetic impurity model, only based on a local reduction of the exchange stiffness constant, have been considered. In order to provide a background for experimental studies, we have varied the parameter related to the pinning potential strength of the magnetic impurity. By adjusting the pinning potential of magnetic impurities and choosing simultaneously a suitable current pulse, we have found that it is possible to obtain domain wall depinning by applying low-intensity and short-duration current pulses. Furthermore, it was considered a planar magnetic nanowire containing a linear distribution of equally-spaced magnetic impurities and we have demonstrated the position control of a single TDW by applying sequential current pulses; that means the wall movement from an impurity to another.

  13. Elasticity of the living abdominal wall in laparoscopic surgery.

    PubMed

    Song, Chengli; Alijani, Afshin; Frank, Tim; Hanna, George; Cuschieri, Alfred

    2006-01-01

    Laparoscopic surgery requires inflation of the abdominal cavity and this offers a unique opportunity to measure the mechanical properties of the living abdominal wall. We used a motion analysis system to study the abdominal wall motion of 18 patients undergoing laparoscopic surgery, and found that the mean Young's modulus was 27.7+/-4.5 and 21.0+/-3.7 kPa for male and female, respectively. During inflation, the abdominal wall changed from a cylinder to a dome shape. The average expansion in the abdominal wall surface was 20%, and a working space of 1.27 x 10(-3)m(3) was created by expansion, reshaping of the abdominal wall and diaphragmatic movement. For the first time, the elasticity of human abdominal wall was obtained from the patients undergoing laparoscopic surgery, and a 3D simulation model of human abdominal wall has been developed to analyse the motion pattern in laparoscopic surgery. Based on this study, a mechanical abdominal wall lift and a surgical simulator for safe/ergonomic port placements are under development.

  14. Coercivity of domain wall motion in thin films of amorphous rare earth-transition metal alloys

    NASA Technical Reports Server (NTRS)

    Mansuripur, M.; Giles, R. C.; Patterson, G.

    1991-01-01

    Computer simulations of a two dimensional lattice of magnetic dipoles are performed on the Connection Machine. The lattice is a discrete model for thin films of amorphous rare-earth transition metal alloys, which have application as the storage media in erasable optical data storage systems. In these simulations, the dipoles follow the dynamic Landau-Lifshitz-Gilbert equation under the influence of an effective field arising from local anisotropy, near-neighbor exchange, classical dipole-dipole interactions, and an externally applied field. Various sources of coercivity, such as defects and/or inhomogeneities in the lattice, are introduced and the subsequent motion of domain walls in response to external fields is investigated.

  15. Motion of a Janus particle very near a wall

    NASA Astrophysics Data System (ADS)

    Rashidi, Aidin; Wirth, Christopher L.

    2017-12-01

    This article describes the simulated Brownian motion of a sphere comprising hemispheres of unequal zeta potential (i.e., "Janus" particle) very near a wall. The simulation tool was developed and used to assist in the methodology development for applying Total Internal Reflection Microscopy (TIRM) to anisotropic particles. Simulations of the trajectory of a Janus sphere with cap density matching that of the base particle very near a boundary were used to construct 3D potential energy landscapes that were subsequently used to infer particle and solution properties, as would be done in a TIRM measurement. Results showed that the potential energy landscape of a Janus sphere has a transition region at the location of the boundary between the two Janus halves, which depended on the relative zeta potential magnitude. The potential energy landscape was fit to accurately obtain the zeta potential of each hemisphere, particle size, minimum potential energy position and electrolyte concentration, or Debye length. We also determined the appropriate orientation bin size and regimes over which the potential energy landscape should be fit to obtain system properties. Our simulations showed that an experiment may require more than 106 observations to obtain a suitable potential energy landscape as a consequence of the multivariable nature of observations for an anisotropic particle. These results illustrate important considerations for conducting TIRM for anisotropic particles.

  16. Primary fascial closure with biologic mesh reinforcement results in lesser complication and recurrence rates than bridged biologic mesh repair for abdominal wall reconstruction: A propensity score analysis.

    PubMed

    Giordano, Salvatore; Garvey, Patrick B; Baumann, Donald P; Liu, Jun; Butler, Charles E

    2017-02-01

    Previous studies suggest that bridged mesh repair for abdominal wall reconstruction may result in worse outcomes than mesh-reinforced, primary fascial closure, particularly when acellular dermal matrix is used. We compared our outcomes of bridged versus reinforced repair using ADM in abdominal wall reconstruction procedures. This retrospective study included 535 consecutive patients at our cancer center who underwent abdominal wall reconstruction either for an incisional hernia or for abdominal wall defects left after excision of malignancies involving the abdominal wall with underlay mesh. A total of 484 (90%) patients underwent mesh-reinforced abdominal wall reconstruction and 51 (10%) underwent bridged repair abdominal wall reconstruction. Acellular dermal matrix was used, respectively, in 98% of bridged and 96% of reinforced repairs. We compared outcomes between these 2 groups using propensity score analysis for risk-adjustment in multivariate analysis and for 1-to-1 matching. Bridged repairs had a greater hernia recurrence rate (33.3% vs 6.2%, P < .001), a greater overall complication rate (59% vs 30%, P = .001), and worse freedom from hernia recurrence (log-rank P <.001) than reinforced repairs. Bridged repairs also had a greater rate of wound dehiscence (26% vs 14%, P = .034) and mesh exposure (10% vs 1%, P = .003) than mesh-reinforced abdominal wall reconstruction. When the treatment method was adjusted for propensity score in the propensity-score-matched pairs (n = 100), we found that the rates of hernia recurrence (32% vs 6%, P = .002), overall complications (32% vs 6%, P = .002), and freedom from hernia recurrence (68% vs 32%, P = .001) rates were worse after bridged repair. We did not observe differences in wound healing and mesh complications between the 2 groups. In our population of primarily cancer patients at MD Anderson Cancer Center bridged repair for abdominal wall reconstruction is associated with worse outcomes than mesh

  17. Noninvasive detection of coronary artery wall thickening with age in healthy subjects using high resolution MRI with beat-to-beat respiratory motion correction.

    PubMed

    Scott, Andrew D; Keegan, Jennifer; Mohiaddin, Raad H; Firmin, David N

    2011-10-01

    To demonstrate coronary artery wall thickening with age in a small healthy cohort using a highly efficient, reliable, and reproducible high-resolution MR technique. A 3D cross-sectional MR vessel wall images (0.7 × 0.7 × 3 mm resolution) with retrospective beat-to-beat respiratory motion correction (B2B-RMC) were obtained in the proximal right coronary artery of 21 healthy subjects (age, 22-62 years) with no known cardiovascular disease. Lumen and outer wall (lumen + vessel wall) areas were measured in one central slice from each subject and average wall thickness and wall area/outer wall area ratio (W/OW) calculated. Imaging was successful in 18 (86%) subjects with average respiratory efficiency 99.3 ± 1.7%. Coronary vessel wall thickness and W/OW significantly correlate with subject age, increasing by 0.088 mm and 0.031 per decade respectively (R = 0.53, P = 0.024 and R = 0.48, P = 0.046). No relationship was found between lumen area and vessel wall thickness (P = NS), but outer wall area increased significantly with vessel wall thickness at 19 mm(2) per mm (P = 0.046). This is consistent with outward vessel wall remodeling. Despite the small size of our healthy cohort, using high-resolution MR imaging and B2B-RMC, we have demonstrated increasing coronary vessel wall thickness and W/OW with age. The results obtained are consistent with outward vessel wall remodeling. Copyright © 2011 Wiley-Liss, Inc.

  18. Swimming trajectories of a three-sphere microswimmer near a wall

    NASA Astrophysics Data System (ADS)

    Daddi-Moussa-Ider, Abdallah; Lisicki, Maciej; Hoell, Christian; Löwen, Hartmut

    2018-04-01

    The hydrodynamic flow field generated by self-propelled active particles and swimming microorganisms is strongly altered by the presence of nearby boundaries in a viscous flow. Using a simple model three-linked sphere swimmer, we show that the swimming trajectories near a no-slip wall reveal various scenarios of motion depending on the initial orientation and the distance separating the swimmer from the wall. We find that the swimmer can either be trapped by the wall, completely escape, or perform an oscillatory gliding motion at a constant mean height above the wall. Using a far-field approximation, we find that, at leading order, the wall-induced correction has a source-dipolar or quadrupolar flow structure where the translational and angular velocities of the swimmer decay as inverse third and fourth powers with distance from the wall, respectively. The resulting equations of motion for the trajectories and the relevant order parameters fully characterize the transition between the states and allow for an accurate description of the swimming behavior near a wall. We demonstrate that the transition between the trapping and oscillatory gliding states is first order discontinuous, whereas the transition between the trapping and escaping states is continuous, characterized by non-trivial scaling exponents of the order parameters. In order to model the circular motion of flagellated bacteria near solid interfaces, we further assume that the spheres can undergo rotational motion around the swimming axis. We show that the general three-dimensional motion can be mapped onto a quasi-two-dimensional representational model by an appropriate redefinition of the order parameters governing the transition between the swimming states.

  19. Characterization of the Test Section Walls at the 14- by 22-Foot Subsonic Tunnel

    NASA Technical Reports Server (NTRS)

    Lunsford, Charles B.; Graves, Sharon S.

    2003-01-01

    The test section walls of the NASA Langley Research Center 14- by 22-Foot Subsonic Tunnel are known to move under thermal and pressure loads. Videogrammetry was used to measure wall motion during the summer of 2002. In addition, a laser distancemeter was used to measure the relative distance between the test section walls at a single point. Distancemeter and videogrammetry results were consistent. Data were analyzed as a function of temperature and pressure to determine their effects on wall motion. Data were collected between 50 and 100 F, 0 and 0.315 Mach, and dynamic pressures of 0 and 120 psf. The overall motion of each wall was found to be less than 0.25 in. and less than facility personnel anticipated. The results show how motion depends on the temperature and pressure inside the test section as well is the position of the boundary layer vane. The repeatability of the measurements was +/-0.06 in. This report describes the methods used to record the motion of the test section walls and the results of the data analysis. Future facility plans include the development of a suitable wall restraint system and the determination of the effects of the wall motion on tunnel calibration.

  20. 3-D simulation of hanging wall effect at dam site

    NASA Astrophysics Data System (ADS)

    Zhang, L.; Xu, Y.

    2017-12-01

    Hanging wall effect is one of the near fault effects. This paper focuses on the difference of the ground motions on the hanging wall side between the footwall side of the fault at dam site considering the key factors, such as actual topography, the rupture process. For this purpose, 3-D ground motions are numerically simulated by the spectrum element method (SEM), which takes into account the physical mechanism of generation and propagation of seismic waves. With the SEM model of 548 million DOFs, excitation and propagation of seismic waves are simulated to compare the difference between the ground motion on the hanging wall side and that on the footwall side. Take Dagangshan region located in China as an example, several seismogenic finite faults with different dip angle are simulated to investigate the hanging wall effect. Furthermore, by comparing the ground motions of the receiving points, the influence of several factors on hanging wall effect is investigated, such as the dip of the fault and the fault type (strike slip fault or dip-slip fault). The peak acceleration on the hanging wall side is obviously larger than those on the footwall side, which numerically evidences the hanging wall effect. Besides, the simulation shows that only when the dip is less than 70° does the hanging wall effect deserve attention.

  1. Dominance of free wall radial motion in global right ventricular function of heart transplant recipients.

    PubMed

    Lakatos, Bálint Károly; Tokodi, Márton; Assabiny, Alexandra; Tősér, Zoltán; Kosztin, Annamária; Doronina, Alexandra; Rácz, Kristóf; Koritsánszky, Kinga Bianka; Berzsenyi, Viktor; Németh, Endre; Sax, Balázs; Kovács, Attila; Merkely, Béla

    2018-03-01

    Assessment of right ventricular (RV) function using conventional echocardiography might be inadequate as the radial motion of the RV free wall is often neglected. Our aim was to quantify the longitudinal and the radial components of RV function using three-dimensional (3D) echocardiography in heart transplant (HTX) recipients. Fifty-one HTX patients in stable cardiovascular condition without history of relevant rejection episode or chronic allograft vasculopathy and 30 healthy volunteers were enrolled. RV end-diastolic (EDV) volume and total ejection fraction (TEF) were measured by 3D echocardiography. Furthermore, we quantified longitudinal (LEF) and radial ejection fraction (REF) by decomposing the motion of the RV using the ReVISION method. RV EDV did not differ between groups (HTX vs control; 96 ± 27 vs 97 ± 2 mL). In HTX patients, TEF was lower, however, tricuspid annular plane systolic excursion (TAPSE) decreased to a greater extent (TEF: 47 ± 7 vs 54 ± 4% [-13%], TAPSE: 11 ± 5 vs 21 ± 4 mm [-48%], P < .0001). In HTX patients, REF/TEF ratio was significantly higher compared to LEF/TEF (REF/TEF vs LEF/TEF: 0.58 ± 0.10 vs 0.27 ± 0.08, P < .0001), while in controls the REF/TEF and LEF/TEF ratio was similar (0.45 ± 0.07 vs 0.47 ± 0.07). Current results confirm the superiority of radial motion in determining RV function in HTX patients. Parameters incorporating the radial motion are recommended to assess RV function in HTX recipients. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Experimental Study of Short-Time Brownian Motion

    NASA Astrophysics Data System (ADS)

    Mo, Jianyong; Simha, Akarsh; Riegler, David; Raizen, Mark

    2015-03-01

    We report our progress on the study of short-time Brownian motion of optically-trapped microspheres. In earlier work, we observed the instantaneous velocity of microspheres in gas and in liquid, verifying a prediction by Albert Einstein from 1907. We now report a more accurate test of the energy equipartition theorem for a particle in liquid. We also observe boundary effects on Brownian motion in liquid by setting a wall near the trapped particle, which changes the dynamics of the motion. We find that the velocity autocorrelation of the particle decreases faster as the particle gets closer to the wall.

  3. Correlation between spin structure oscillations and domain wall velocities

    PubMed Central

    Bisig, André; Stärk, Martin; Mawass, Mohamad-Assaad; Moutafis, Christoforos; Rhensius, Jan; Heidler, Jakoba; Büttner, Felix; Noske, Matthias; Weigand, Markus; Eisebitt, Stefan; Tyliszczak, Tolek; Van Waeyenberge, Bartel; Stoll, Hermann; Schütz, Gisela; Kläui, Mathias

    2013-01-01

    Magnetic sensing and logic devices based on the motion of magnetic domain walls rely on the precise and deterministic control of the position and the velocity of individual magnetic domain walls in curved nanowires. Varying domain wall velocities have been predicted to result from intrinsic effects such as oscillating domain wall spin structure transformations and extrinsic pinning due to imperfections. Here we use direct dynamic imaging of the nanoscale spin structure that allows us for the first time to directly check these predictions. We find a new regime of oscillating domain wall motion even below the Walker breakdown correlated with periodic spin structure changes. We show that the extrinsic pinning from imperfections in the nanowire only affects slow domain walls and we identify the magnetostatic energy, which scales with the domain wall velocity, as the energy reservoir for the domain wall to overcome the local pinning potential landscape. PMID:23978905

  4. Time-evolving of very large-scale motions in a turbulent channel flow

    NASA Astrophysics Data System (ADS)

    Hwang, Jinyul; Lee, Jin; Sung, Hyung Jin; Zaki, Tamer A.

    2014-11-01

    Direct numerical simulation (DNS) data of a turbulent channel flow at Reτ = 930 was scrutinized to investigate the formation of very large-scale motions (VLSMs) by merging of two large-scale motions (LSMs), aligned in the streamwise direction. We mainly focused on the supportive motions by the near-wall streaks during the merging of the outer LSMs. From visualization of the instantaneous flow fields, several low-speed streaks in the near-wall region were collected in the spanwise direction, when LSMs were concatenated in the outer region. The magnitude of the streamwise velocity fluctuations in the streaks was intensified during the spanwise merging of the near-wall streaks. Conditionally-averaged velocity fields around the merging of the outer LSMs showed that the intensified near-wall motions were induced by the outer LSMs and extended over the near-wall regions. The intense near-wall motions influence the formation of the outer low-speed regions as well as the reduction of the convection velocity of the downstream LSMs. The interaction between the near-wall and the outer motions is the essential origin of the different convection velocities of the upstream and downstream LSMs for the formation process of VLSMs by merging. This work was supported by the Creative Research Initiatives (No. 2014-001493) program of the National Research Foundation of Korea (MSIP) and partially supported by KISTI under the Strategic Supercomputing Support Program.

  5. The dynamics of domain walls and strings

    NASA Technical Reports Server (NTRS)

    Gregory, Ruth; Haws, David; Garfinkle, David

    1989-01-01

    The leading order finite-width corrections to the equation of motion describing the motion of a domain wall are derived. The regime in which this equation of motion is invalid is discussed. Spherically and cylindrically symmetric solutions to this equation of motion are found. A misconception that has arisen in recent years regarding the rigidity (or otherwise) of cosmic strings is also clarified.

  6. Skyrmion domain wall collision and domain wall-gated skyrmion logic

    NASA Astrophysics Data System (ADS)

    Xing, Xiangjun; Pong, Philip W. T.; Zhou, Yan

    2016-08-01

    Skyrmions and domain walls are significant spin textures of great technological relevance to magnetic memory and logic applications, where they can be used as carriers of information. The unique topology of skyrmions makes them display emergent dynamical properties as compared with domain walls. Some studies have demonstrated that the two topologically inequivalent magnetic objects could be interconverted by using cleverly designed geometric structures. Here, we numerically address the skyrmion domain wall collision in a magnetic racetrack by introducing relative motion between the two objects based on a specially designed junction. An electric current serves as the driving force that moves a skyrmion toward a trapped domain wall pair. We see different types of collision dynamics depending on the driving parameters. Most importantly, the modulation of skyrmion transport using domain walls is realized in this system, allowing a set of domain wall-gated logical NOT, NAND, and NOR gates to be constructed. This work provides a skyrmion-based spin-logic architecture that is fully compatible with racetrack memories.

  7. Current induced domain wall motion in antiferromagnetically coupled (Co70Fe30/Pd) multilayer nanowires

    NASA Astrophysics Data System (ADS)

    Meng, Zhaoliang; He, Shikun; Huang, Lisen; Qiu, Jinjun; Zhou, Tiejun; Panagopoulos, Christos; Han, Guchang; Teo, Kie-Leong

    2016-10-01

    We investigate the current induced domain wall (DW) motion in the ultrathin CoFe/Pd multilayer based synthetically antiferromagnetic (SAF) structure nanowires by anomalous Hall effect measurement. The threshold current density (Jth) for the DW displacement decreases and the DW velocity (v) increases accordingly with the exchange coupling Jex between the top and bottom ferromagnetic CoFe/Pd multilayers. The lowest Jth = 9.3 × 1010 A/m2 and a maximum v = 150 m/s with J = 1.5 × 1012 A/m2 are achieved due to the exchange coupling torque (ECT) generated in the SAF structure. The strength of ECT is dependent on both of Jex and the strong spin-orbit torque mainly generated by Ta layer.

  8. Comparison between collective coordinate models for domain wall motion in PMA nanostrips in the presence of the Dzyaloshinskii-Moriya interaction

    NASA Astrophysics Data System (ADS)

    Vandermeulen, J.; Nasseri, S. A.; Van de Wiele, B.; Durin, G.; Van Waeyenberge, B.; Dupré, L.

    2018-03-01

    Lagrangian-based collective coordinate models for magnetic domain wall (DW) motion rely on an ansatz for the DW profile and a Lagrangian approach to describe the DW motion in terms of a set of time-dependent collective coordinates: the DW position, the DW magnetization angle, the DW width and the DW tilting angle. Another approach was recently used to derive similar equations of motion by averaging the Landau-Lifshitz-Gilbert equation without any ansatz, and identifying the relevant collective coordinates afterwards. In this paper, we use an updated version of the semi-analytical equations to compare the Lagrangian-based collective coordinate models with micromagnetic simulations for field- and STT-driven (spin-transfer torque-driven) DW motion in Pt/CoFe/MgO and Pt/Co/AlOx nanostrips. Through this comparison, we assess the accuracy of the different models, and provide insight into the deviations of the models from simulations. It is found that the lack of terms related to DW asymmetry in the Lagrangian-based collective coordinate models significantly contributes to the discrepancy between the predictions of the most accurate Lagrangian-based model and the micromagnetic simulations in the field-driven case. This is in contrast to the STT-driven case where the DW remains symmetric.

  9. Abdominal Wall Reconstruction with Concomitant Ostomy-Associated Hernia Repair: Outcomes and Propensity Score Analysis.

    PubMed

    Mericli, Alexander F; Garvey, Patrick B; Giordano, Salvatore; Liu, Jun; Baumann, Donald P; Butler, Charles E

    2017-03-01

    The optimal strategy for abdominal wall reconstruction in the presence of a stomal-site hernia is unclear. We hypothesized that the rate of ventral hernia recurrence in patients undergoing a combined ventral hernia repair and stomal-site herniorraphy would not differ clinically from the ventral hernia recurrence rate in patients undergoing an isolated ventral hernia repair. We also hypothesized that bridged ventral hernia repairs result in worse outcomes compared with reinforced repairs, regardless of stomal hernia. We retrospectively reviewed prospectively collected data from consecutive abdominal wall reconstructions performed with acellular dermal matrix (ADM) at a single center between 2000 and 2015. We compared patients who underwent a ventral hernia repair alone (AWR) and those who underwent both a ventral hernia repair and ostomy-associated herniorraphy (AWR+O). We conducted a propensity score matched analysis to compare the outcomes between the 2 groups. Multivariable Cox proportional hazards and logistic regression models were used to study associations between potential predictive or protective reconstructive strategies and surgical outcomes. We included 499 patients (median follow-up 27.2 months; interquartile range [IQR] 12.4 to 46.6 months), 118 AWR+O and 381 AWR. After propensity score matching, 91 pairs were obtained. Ventral hernia recurrence was not statistically associated with ostomy-associated herniorraphy (adjusted hazard ratio [HR] 0.7; 95% CI 0.3 to 1.5; p = 0.34). However, the AWR+O group experienced a significantly higher percentage of surgical site occurrences (34.1%) than the AWR group (18.7%; adjusted odds ratio 2.3; 95% CI 1.4 to 3.7; p < 0.001). In the AWR group, there were significantly fewer ventral hernia recurrences when the repair was reinforced compared with bridged (5.3% vs 38.5%; p < 0.001). There was no statistically significant difference in ventral hernia recurrence between the AWR and AWR+O groups. Bridging was associated

  10. A Countermeasure for Space Motion Sickness

    NASA Technical Reports Server (NTRS)

    Reschke, M. F.; Somers, J. T.; Leigh, R. J.; Jones, G. Melvill

    2006-01-01

    the possibility of producing functionally useful adaptation during space flight without the penalty of disabling motion sickness by controlling the rate of the adaptive process by means of an appropriate stroboscopically presented environment. After several recent meetings with Professor Melvill Jones, we were encouraged to repeat the motion sickness portions of his and Mandl's 1981 stroboscopic experiment. In conducting this experiment we used a randomized cross-over design where subjects were randomly assigned to either a stroboscopic flash or no strobe for their first exposure in the experimental design. Twenty subjects (19 subjects completed the study) read a short passage from Treasure Island mounted on the wall approximately 1 m from their eyes while wearing left-right reversing prisms. The strobe on time of 3 microseconds and flash frequency of 4 Hz was set to equal that used in the original study. Motion sickness was scored using a modified Miller and Graybiel scale that we constructed to include symptoms that may be elicited under conditions where reversing prisms are worn. On this scale a score of 5 represented Malaise IIa (mild motion sickness) and a score of 8 or above is approaching frank sickness. Symptoms were tracked and recorded every 5 min during the task. Testing was limited to 30 min unless the subject had reached the MIIa score, at which time the test was terminated. Performance under stroboscopic illumination was significantly better than when the subjects read under normal room illumination while wearing the left-right reversing prisms. Based on these results we developed a goggle system using LCD material that can be strobed. To evaluate the effectiveness of stroboscopic goggles we tested an additional 9 subjects in addition to retesting 10 used in the stroboscopic pilot study described above. These 19 subjects wore a pair of strobing LCD goggles that could be cycled at 4 Hz. These subjects wore the goggles while also wearing left-right reversg

  11. Coexistence of bounded and unbounded motions in a bouncing ball model

    NASA Astrophysics Data System (ADS)

    Marò, Stefano

    2013-05-01

    We consider the model describing the vertical motion of a ball falling with constant acceleration on a wall and elastically reflected. The wall is supposed to move in the vertical direction according to a given periodic function f. We apply the Aubry-Mather theory to the generating function in order to prove the existence of bounded motions with prescribed mean time between the bounces. As the existence of unbounded motions is known, it is possible to find a class of functions f that allow both bounded and unbounded motions.

  12. Aortic dissection simulation models for clinical support: fluid-structure interaction vs. rigid wall models.

    PubMed

    Alimohammadi, Mona; Sherwood, Joseph M; Karimpour, Morad; Agu, Obiekezie; Balabani, Stavroula; Díaz-Zuccarini, Vanessa

    2015-04-15

    The management and prognosis of aortic dissection (AD) is often challenging and the use of personalised computational models is being explored as a tool to improve clinical outcome. Including vessel wall motion in such simulations can provide more realistic and potentially accurate results, but requires significant additional computational resources, as well as expertise. With clinical translation as the final aim, trade-offs between complexity, speed and accuracy are inevitable. The present study explores whether modelling wall motion is worth the additional expense in the case of AD, by carrying out fluid-structure interaction (FSI) simulations based on a sample patient case. Patient-specific anatomical details were extracted from computed tomography images to provide the fluid domain, from which the vessel wall was extrapolated. Two-way fluid-structure interaction simulations were performed, with coupled Windkessel boundary conditions and hyperelastic wall properties. The blood was modelled using the Carreau-Yasuda viscosity model and turbulence was accounted for via a shear stress transport model. A simulation without wall motion (rigid wall) was carried out for comparison purposes. The displacement of the vessel wall was comparable to reports from imaging studies in terms of intimal flap motion and contraction of the true lumen. Analysis of the haemodynamics around the proximal and distal false lumen in the FSI model showed complex flow structures caused by the expansion and contraction of the vessel wall. These flow patterns led to significantly different predictions of wall shear stress, particularly its oscillatory component, which were not captured by the rigid wall model. Through comparison with imaging data, the results of the present study indicate that the fluid-structure interaction methodology employed herein is appropriate for simulations of aortic dissection. Regions of high wall shear stress were not significantly altered by the wall motion

  13. PREFACE: Domain wall dynamics in nanostructures Domain wall dynamics in nanostructures

    NASA Astrophysics Data System (ADS)

    Marrows, C. H.; Meier, G.

    2012-01-01

    forms of ordered phases such as antiferromagnetism and ferroelectricity. We would like to thank the scientists from all over the world who happily agreed to contribute their latest results to this special issue, and the Journal of Physics: Condensed Matter staff for their help, patience and professionalism. In such a fast-moving field it is not possible to give a definitive account, and this special issue can be no more than a snapshot of the current state of knowledge regarding this topic. Nevertheless, we hope that this collection of papers is a useful resource for experienced workers in the field, forms a useful introduction to researchers early in their careers and inspires others in related areas of nanotechnology to enter into the study of domain dynamics in nanostructures. Domain wall dynamics in nanostructures contents Temperature estimation in a ferromagnetic Fe-Ni nanowire involving a current-driven domain wall motionA Yamaguchi, A Hirohata, T Ono and H Miyajima Magnetization reversal in magnetic nanostripes via Bloch wall formation M Zeisberger and R Mattheis Magnetic soft x-ray microscopy of the domain wall depinning process in permalloy magnetic nanowiresMi-Young Im, Lars Bocklage, Guido Meier and Peter Fischer Domain wall propagation in meso- and nanoscale ferroelectrics R G P McQuaid, M McMillen, L-W Chang, A Gruverman and J M Gregg Transverse and vortex domain wall structure in magnetic nanowires with uniaxial in-plane anisotropyM T Bryan, S Bance, J Dean, T Schrefl and D A Allwood The stochastic nature of the domain wall motion along high perpendicular anisotropy strips with surface roughness Eduardo Martinez Temperature-dependent dynamics of stochastic domain-wall depinning in nanowiresClemens Wuth, Peter Lendecke and Guido Meier Controlled pinning and depinning of domain walls in nanowires with perpendicular magnetic anisotropyTheo Gerhardt, André Drews and Guido Meier The interaction of transverse domain wallsBenjamin Krüger The increase of the

  14. Domain wall kinetics of lithium niobate single crystals near the hexagonal corner

    NASA Astrophysics Data System (ADS)

    Choi, Ju Won; Ko, Do-Kyeong; Yu, Nan Ei; Kitamura, Kenji; Ro, Jung Hoon

    2015-03-01

    A mesospheric approach based on a simple microscopic 2D Ising model in a hexagonal lattice plane is proposed to explain macroscopic "asymmetric in-out domain wall motion" observation in the (0001) plane of MgO-doped stoichiometric lithium niobate. Under application of an electric field that was higher than the conventional coercive field (Ec) to the ferroelectric crystal, a natural hexagonal domain was obtained with walls that were parallel to the Y-axis of the crystal. When a fraction of the coercive field of around 0.1Ec is applied in the reverse direction, this hexagonal domain is shrunk (moved inward) from the corner site into a shape with a corner angle of around 150° and 15° wall slopes to the Y-axis. A flipped electric field of 0.15Ec is then applied to recover the natural hexagonal shape, and the 150° corner shape changes into a flat wall with 30° slope (moved outward). The differences in corner domain shapes between inward and outward domain motion were analyzed theoretically in terms of corner and wall site energies, which are described using the domain corner angle and wall slope with respect to the crystal Y-axis, respectively. In the inward domain wall motion case, the energy levels of the evolving 150° domain corner and 15° slope walls are most competitive, and could co-exist. In the outward case, the energy levels of corners with angles >180° are highly stable when compared with the possible domain walls; only a flat wall with 30° slope to the Y-axis is possible during outward motion.

  15. Rotational Motion of Axisymmetric Marangoni Swimmers

    NASA Astrophysics Data System (ADS)

    Rothstein, Jonathan; Uvanovic, Nick

    2017-11-01

    A series of experiments will be presented investigating the motion of millimeter-sized particles on the surface of water. The particles were partially coated with ethanol and carefully placed on a water interface in a series of Petri dishes with different diameters. High speed particle motion was driven by strong surface tension gradients as the ethanol slowly diffuses from the particles into the water resulting in a Marangoni flow. The velocity and acceleration of the particles where measured. In addition to straight line motion, the presence of the bounding walls of the circular Petri dish was found to induce an asymmetric, rotational motion of the axisymmetric Marangoni swimmers. The rotation rate and radius of curvature was found to be a function of the size of the Petri dish and the curvature of the air-water interface near the edge of the dish. For large Petri dishes or small particles, rotation motion was observed far from the bounding walls. In these cases, the symmetry break appears to be the result of the onset of votex shedding. Finally, multiple spherical particles were observed to undergo assembly driven by capillary forces followed by explosive disassembly.

  16. Translational Response of Toe-Restrained Retaining Walls to Earthquake Ground Motions Using CorpsWallSlip (CWSlip)

    DTIC Science & Technology

    2007-06-01

    corresponding software developed for the translational response of rock- founded retaining walls buttressed at their toe by a reinforced concrete slab...by a Reinforced Concrete Slab ...........................................................................................................32 2.1...2.5 New translational analysis model of a wall retaining a partially submerged backfill and buttressed by a reinforced concrete slab

  17. Broadband boundary effects on Brownian motion.

    PubMed

    Mo, Jianyong; Simha, Akarsh; Raizen, Mark G

    2015-12-01

    Brownian motion of particles in confined fluids is important for many applications, yet the effects of the boundary over a wide range of time scales are still not well understood. We report high-bandwidth, comprehensive measurements of Brownian motion of an optically trapped micrometer-sized silica sphere in water near an approximately flat wall. At short distances we observe anisotropic Brownian motion with respect to the wall. We find that surface confinement not only occurs in the long time scale diffusive regime but also in the short time scale ballistic regime, and the velocity autocorrelation function of the Brownian particle decays faster than that of a particle in bulk fluid. Furthermore, at low frequencies the thermal force loses its color due to the reflected flow from the no-slip boundary. The power spectrum of the thermal force on the particle near a no-slip boundary becomes flat at low frequencies. This detailed understanding of boundary effects on Brownian motion opens a door to developing a 3D microscope using particles as remote sensors.

  18. Evaluation of motion artifact metrics for coronary CT angiography.

    PubMed

    Ma, Hongfeng; Gros, Eric; Szabo, Aniko; Baginski, Scott G; Laste, Zachary R; Kulkarni, Naveen M; Okerlund, Darin; Schmidt, Taly G

    2018-02-01

    This study quantified the performance of coronary artery motion artifact metrics relative to human observer ratings. Motion artifact metrics have been used as part of motion correction and best-phase selection algorithms for Coronary Computed Tomography Angiography (CCTA). However, the lack of ground truth makes it difficult to validate how well the metrics quantify the level of motion artifact. This study investigated five motion artifact metrics, including two novel metrics, using a dynamic phantom, clinical CCTA images, and an observer study that provided ground-truth motion artifact scores from a series of pairwise comparisons. Five motion artifact metrics were calculated for the coronary artery regions on both phantom and clinical CCTA images: positivity, entropy, normalized circularity, Fold Overlap Ratio (FOR), and Low-Intensity Region Score (LIRS). CT images were acquired of a dynamic cardiac phantom that simulated cardiac motion and contained six iodine-filled vessels of varying diameter and with regions of soft plaque and calcifications. Scans were repeated with different gantry start angles. Images were reconstructed at five phases of the motion cycle. Clinical images were acquired from 14 CCTA exams with patient heart rates ranging from 52 to 82 bpm. The vessel and shading artifacts were manually segmented by three readers and combined to create ground-truth artifact regions. Motion artifact levels were also assessed by readers using a pairwise comparison method to establish a ground-truth reader score. The Kendall's Tau coefficients were calculated to evaluate the statistical agreement in ranking between the motion artifacts metrics and reader scores. Linear regression between the reader scores and the metrics was also performed. On phantom images, the Kendall's Tau coefficients of the five motion artifact metrics were 0.50 (normalized circularity), 0.35 (entropy), 0.82 (positivity), 0.77 (FOR), 0.77(LIRS), where higher Kendall's Tau signifies higher

  19. Corrections to the thin wall approximation in general relativity

    NASA Technical Reports Server (NTRS)

    Garfinkle, David; Gregory, Ruth

    1989-01-01

    The question is considered whether the thin wall formalism of Israel applies to the gravitating domain walls of a lambda phi(exp 4) theory. The coupled Einstein-scalar equations that describe the thick gravitating wall are expanded in powers of the thickness of the wall. The solutions of the zeroth order equations reproduce the results of the usual Israel thin wall approximation for domain walls. The solutions of the first order equations provide corrections to the expressions for the stress-energy of the wall and to the Israel thin wall equations. The modified thin wall equations are then used to treat the motion of spherical and planar domain walls.

  20. Sensing of minute airflow motions near walls using pappus-type nature-inspired sensors

    PubMed Central

    Mikulich, Vladimir

    2017-01-01

    This work describes the development and use of pappus-like structures as sensitive sensors to detect minute air-flow motions. We made such sensors from pappi taken from nature-grown seed, whose filiform hairs’ length-scale is suitable for the study of large-scale turbulent convection flows. The stem with the pappus on top is fixated on an elastic membrane on the wall and tilts under wind-load proportional to the velocity magnitude in direction of the wind, similar as the biological sensory hairs found in spiders, however herein the sensory hair has multiple filiform protrusions at the tip. As the sensor response is proportional to the drag on the tip and a low mass ensures a larger bandwidth, lightweight pappus structures similar as those found in nature with documented large drag are useful to improve the response of artificial sensors. The pappus of a Dandelion represents such a structure which has evolved to maximize wind-driven dispersion, therefore it is used herein as the head of our sensor. Because of its multiple hairs arranged radially around the stem it generates uniform drag for all wind directions. While still being permeable to the flow, the hundreds of individual hairs on the tip of the sensor head maximize the drag and minimize influence of pressure gradients or shear-induced lift forces on the sensor response as they occur in non-permeable protrusions. In addition, the flow disturbance by the sensor itself is limited. The optical recording of the head-motion allows continuously remote-distance monitoring of the flow fluctuations in direction and magnitude. Application is shown for the measurement of a reference flow under isothermal conditions to detect the early occurrence of instabilities. PMID:28658272

  1. Spin Hall driven domain wall motion in magnetic bilayers coupled by a magnetic oxide interlayer

    NASA Astrophysics Data System (ADS)

    Liu, Yang; Furuta, Masaki; Zhu, Jian-Gang Jimmy

    2018-05-01

    mCell, previously proposed by our group, is a four-terminal magnetoresistive device with isolated write- and read-paths for all-spin logic and memory applications. A mCell requires an electric-insulating magnetic layer to couple the spin Hall driven write-path to the magnetic free layer of the read-path. Both paths are magnetic layers with perpendicular anisotropy and their perpendicularly oriented magnetization needs to be maintained with this insertion layer. We have developed a magnetic oxide (FeOx) insertion layer to serve for these purposes. We show that the FeOx insertion layer provides sufficient magnetic coupling between adjacent perpendicular magnetic layers. Resistance measurement shows that this magnetic oxide layer can act as an electric-insulating layer. In addition, spin Hall driven domain wall motion in magnetic bi-layers coupled by the FeOx insertion layer is significantly enhanced compared to that in magnetic single layer; it also requires low voltage threshold that poses possibility for power-efficient device applications.

  2. Is the great attractor really a great wall

    NASA Technical Reports Server (NTRS)

    Stebbins, Albert; Turner, Michael S.

    1988-01-01

    Some of the cosmological consequences are discussed of a late time phase transition which produces light domain walls. The observed peculiar velocity field of the Universe and the observed isotropy of the microwave background radiation severely constrain the wall surface density in such a scenario. The most interesting consequence of such a phase transition is the possibility that the local, coherent streaming motion reported by the Seven Samurai could be explained by the repulsive effect of a relic domain wall with the Hubble volume (the Great Wall).

  3. Quantitative Assessment of Regional Wall Motion Abnormalities Using Dual-Energy Digital Subtraction Intravenous Ventriculography

    NASA Astrophysics Data System (ADS)

    McCollough, Cynthia H.

    Healthy portions of the left ventricle (LV) can often compensate for regional dysfunction, thereby masking regional disease when global indices of LV function are employed. Thus, quantitation of regional function provides a more useful method of assessing LV function, especially in diseases that have regional effects such as coronary artery disease. This dissertation studied the ability of a phase -matched dual-energy digital subtraction angiography (DE -DSA) technique to quantitate changes in regional LV systolic volume. The potential benefits and a theoretical description of the DE imaging technique are detailed. A correlated noise reduction algorithm is also presented which raises the signal-to-noise ratio of DE images by a factor of 2 -4. Ten open-chest dogs were instrumented with transmural ultrasonic crystals to assess regional LV function in terms of systolic normalized-wall-thickening rate (NWTR) and percent-systolic-thickening (PST). A pneumatic occluder was placed on the left-anterior-descending (LAD) coronary artery to temporarily reduce myocardial blood flow, thereby changing regional LV function in the LAD bed. DE-DSA intravenous left ventriculograms were obtained at control and four levels of graded myocardial ischemia, as determined by reductions in PST. Phase-matched images displaying changes in systolic contractile function were created by subtracting an end-systolic (ES) control image from ES images acquired at each level of myocardial ischemia. The resulting wall-motion difference signal (WMD), which represents a change in regional systolic volume between the control and ischemic states, was quantitated by videodensitometry and compared with changes in NWTR and PST. Regression analysis of 56 data points from 10 animals shows a linear relationship between WMD and both NWTR and PST: WMD = -2.46 NWTR + 13.9, r = 0.64, p < 0.001; WMD = -2.11 PST + 18.4, r = 0.54, p < 0.001. Thus, changes in regional ES LV volume between rest and ischemic states, as

  4. Current-controlled unidirectional edge-meron motion

    NASA Astrophysics Data System (ADS)

    Xing, Xiangjun; Pong, Philip W. T.; Zhou, Yan

    2016-11-01

    In order to address many of the challenges and bottlenecks currently experienced by traditional charge-based technologies, various alternatives are being actively explored to provide potential solutions of device miniaturization and scaling in the post-Moore's-law era. Amongst these alternatives, spintronic physics and devices have recently attracted rapidly increasing interest by exploiting the additional degree of electrons-spin. For example, magnetic domain-wall racetrack-memory and logic devices have been realized via manipulating domain-wall motion. As compared to domain-wall-based devices, magnetic skyrmions have the advantages of ultrasmall size (typically 5-100 nm in diameter), facile current-driven motion, topological stability, and peculiar emergent electrodynamics, promising for next-generation electronics applications in the post-Moore's-law regime. Here, a magnetic meron device, which behaves similarly to a PN-junction diode, is demonstrated for the first time, by tailoring the current-controlled unidirectional motion of edge-merons (i.e., fractional skyrmions) in a nanotrack with interfacial Dzyaloshinskii-Moriya interaction. The working principles of the meron device, theoretically predicted from the Thiele equation for topological magnetic objects, are further verified using micromagnetic simulations. The present study has revealed the topology-independent transport property of different magnetic objects and is expected to open the vista toward integrated composite circuitry (with unified data storage and processing) based on a single magnetic chip, as the meron device can be used, either as a building block to develop complex logic components or as a signal controller to interconnect skyrmion, domain-wall, and even spin-wave devices.

  5. Schematic construction of flanged nanobearings from double-walled carbon nanotubes.

    PubMed

    Shenai, Prathamesh Mahesh; Zhao, Yang

    2010-08-01

    The performance of nanobearings constructed from double walled carbon nanotubes is considered to be crucially dependent on the initial rotational speed. Wearless rotation ceases for a nanobearing operating beyond a certain angular velocity. We propose a new design of nanobearings by manipulation of double walled carbon nanotubes leading to a flanged structure which possesses a built-in hindrance to the intertube oscillation without obstructing rotational motion. Through blocking the possible leakage path for rotational kinetic energy to the intertube oscillatory motion, the flanged bearing lowers its dissipative tendency when set into motion. Using molecular dynamics, it is shown that on account of its distinctive structure, the flanged bearing has superior operating characteristics and a broader working domain.

  6. Spatial task performance, sex differences, and motion sickness susceptibility.

    PubMed

    Levine, Max E; Stern, Robert M

    2002-10-01

    There are substantial individual differences in susceptibility to motion sickness, yet little is known about what mediates these differences. Spatial ability and sex have been suggested as possible factors in this relationship. 89 participants (57 women) were administered a Motion Sickness Questionnaire that assesses motion sickness susceptibility, a Water-level Task that gauges sensitivity to gravitational upright, and a Mental Rotation Task that tests an individual's awareness of how objects typically move in space. Significant sex differences were observed in performance of both the Water-level Task (p<.01), and the Mental Rotation Task (p<.005), with women performing less accurately than men. Women also had significantly higher scores on the Motion Sickness Questionnaire (p<.005). Among men, but not women, significant negative relationships were observed between Water-level Task performance and Motion Sickness Questionnaire score (p<.001) and between Mental Rotation Task performance and Motion Sickness Questionnaire score (p<.005). In conclusion, women performed significantly more poorly than men did on the spatial ability tasks and reported significantly more bouts of motion sickness. In addition, men showed a significant negative relationship between spatial ability and motion sickness susceptibility.

  7. The predictive value of 201Tl rest-redistribution and 18F-fluorodeoxyglucose SPECT for wall motion recovery after recent reperfused myocardial infarction.

    PubMed

    González, Patricio; Massardo, Teresa; Coll, Claudia; Humeres, Pamela; Sierralta, Paulina; Jofré, M Josefina; Yovanovich, Jorge; Aramburu, Ivonne; Brugère, Solange; Chamorro, Hernán

    2004-04-01

    201Tl and 18F-FDG are useful for acute myocardial infarction (MI) assessment. The goal of this study was to compare their predictive value for wall motion recovery in the culprit area after a recent reperfused MI using SPECT technique. Forty-one patients (mean age: 56 +/- 12 years) were included, 81% of them male; all were studied within 1-24 days post MI. They underwent angioplasty in 27 cases (12 primary); bypass grafting in 10 cases and successful thrombolysis in 4. SPECT 201Tl injected at rest and redistribution (R-R) and also 18F-FDG, were performed on different days. Processed tomograms were interpreted blinded to clinical or angiographic data. Segmental wall motion assessed with echocardiography at baseline was compared with the 3 month follow up. Sensitivity [Confidence Interval] for 201Tl R-R was 74.6% [60.5-84.5], for FDG it was 82.1% [70.8-90.4]; specificities were 73% [64.3-80.5] and 54.8% [45.6-63.7], respectively. 18F-FDG tended to be more sensitive than 201Tl R-R, but the latter was more specific (p < 0.0004). Both 201Tl RR and 18F-FDG presented high negative predictive value (p: ns). In recent MI, SPECT 201Tl R-R is a valuable and widely available technique for viability detection, with similar sensitivity and significant better specificity than SPECT 18F-FDG.

  8. Wall-motion tracking in fetal echocardiography-Influence of frame rate on longitudinal strain analysis assessed by two-dimensional speckle tracking.

    PubMed

    Enzensberger, Christian; Achterberg, Friederike; Graupner, Oliver; Wolter, Aline; Herrmann, Johannes; Axt-Fliedner, Roland

    2017-06-01

    Frame rates (FR) used for strain analysis assessed by speckle tracking in fetal echocardiography show a considerable variation. The aim of this study was to investigate the influence of the FR on strain analysis in 2D speckle tracking. Fetal echocardiography was performed prospectively on a Toshiba Aplio 500 system and a Toshiba Artida system, respectively. Based on an apical or basal four-chamber view of the fetal heart, cine loops were stored with a FR of 30 fps (Aplio 500) and 60 fps (Artida/Aplio 500). For both groups (30fps and 60fps), global and segmental longitudinal peak systolic strain (LPSS) values of both, left (LV) and right ventricle (RV), were assessed by 2D wall-motion tracking. A total of 101 fetuses, distributed to three study groups, were included. The mean gestational age was 25.2±5.0 weeks. Mean global LPSS values for RV in the 30 fps group and in the 60 fps group were -16.07% and -16.47%, respectively. Mean global LPSS values for LV in the 30 fps group and in the 60 fps group were -17.54% and -17.06%, respectively. Comparing global and segmental LPSS values of both, the RV and LV, did not show any statistically significant differences within the two groups. Performance of myocardial 2D strain analysis by wall-motion tracking was feasible with 30 and 60 fps. Obtained global and segmental LPSS values of both ventricles were relatively independent from acquisition rate. © 2017, Wiley Periodicals, Inc.

  9. How to push a block along a wall

    NASA Technical Reports Server (NTRS)

    Mason, Matthew T.

    1989-01-01

    Some robot tasks require manipulation of objects that may be touching other fixed objects. The effects of friction and kinematic constraint must be anticipated, and may even be exploited to accomplish the task. An example task, a dynamic analysis, and appropriate effector motions are presented. The goal is to move a rectangular block along a wall, so that one side of the block maintains contact with the wall. Two solutions that push the block along the wall are discussed.

  10. Motion sickness history, food neophobia, and sensation seeking.

    PubMed

    Alley, Thomas R; Willet, Kathleen A; Muth, Eric R

    2006-06-01

    Motion sickness is believed to be caused by conflicting sensory signals, a situation that mimics the effects of ingesting certain toxins. Thus, one might suspect that individuals who have experienced a relatively high frequency of motion sickness may be particularly vigilant about avoiding anything that produces nausea, induding potentially nauseating toxins. Consequently, they may be more resistant to trying new foods, i.e., be more food neophobic, since unfamiliar foods can have unexpected adverse effects due to toxins or allergens. Likewise, many highly stimulating experiences can trigger motion sickness, so individuals who are more susceptible may be more prone to avoid such experiences, i.e., be less sensation seeking. Finally, it was expected that food neophobia would be more frequent in individuals low on sensation seeking tendencies. Self-reported motion sickness history in 308 adults (M= 18.8 yr.; SD = 1.6) was correlated with scores on the Arnett Inventory of Sensation Seeking and the Food Neophobia Scale. As predicted, greater history of motion sickness was associated with lower Sensation Seeking scores. Food Neophobia was not correlated with motion sickness history but, as expected, was negatively correlated (r = -.42) with scores on Sensation Seeking. Further research is recommended that measures actual sensitivity to motion sickness.

  11. Domain wall in a quantum anomalous Hall insulator as a magnetoelectric piston

    NASA Astrophysics Data System (ADS)

    Upadhyaya, Pramey; Tserkovnyak, Yaroslav

    2016-07-01

    We theoretically study the magnetoelectric coupling in a quantum anomalous Hall insulator state induced by interfacing a dynamic magnetization texture to a topological insulator. In particular, we propose that the quantum anomalous Hall insulator with a magnetic configuration of a domain wall, when contacted by electrical reservoirs, acts as a magnetoelectric piston. A moving domain wall pumps charge current between electrical leads in a closed circuit, while applying an electrical bias induces reciprocal domain-wall motion. This pistonlike action is enabled by a finite reflection of charge carriers via chiral modes imprinted by the domain wall. Moreover, we find that, when compared with the recently discovered spin-orbit torque-induced domain-wall motion in heavy metals, the reflection coefficient plays the role of an effective spin-Hall angle governing the efficiency of the proposed electrical control of domain walls. Quantitatively, this effective spin-Hall angle is found to approach a universal value of 2, providing an efficient scheme to reconfigure the domain-wall chiral interconnects for possible memory and logic applications.

  12. Magnetic domain wall creep and depinning: A scalar field model approach

    NASA Astrophysics Data System (ADS)

    Caballero, Nirvana B.; Ferrero, Ezequiel E.; Kolton, Alejandro B.; Curiale, Javier; Jeudy, Vincent; Bustingorry, Sebastian

    2018-06-01

    Magnetic domain wall motion is at the heart of new magnetoelectronic technologies and hence the need for a deeper understanding of domain wall dynamics in magnetic systems. In this context, numerical simulations using simple models can capture the main ingredients responsible for the complex observed domain wall behavior. We present a scalar field model for the magnetization dynamics of quasi-two-dimensional systems with a perpendicular easy axis of magnetization which allows a direct comparison with typical experimental protocols, used in polar magneto-optical Kerr effect microscopy experiments. We show that the thermally activated creep and depinning regimes of domain wall motion can be reached and the effect of different quenched disorder implementations can be assessed with the model. In particular, we show that the depinning field increases with the mean grain size of a Voronoi tessellation model for the disorder.

  13. Toying with Motion.

    ERIC Educational Resources Information Center

    Galus, Pamela J.

    2002-01-01

    Presents a variety of activities that support the development of an understanding of Newton's laws of motion. Activities use toy cars, mobile roads, and a seat-of-nails. Includes a scoring rubric. (DDR)

  14. Domain-wall motion at an ultrahigh speed driven by spin-orbit torque in synthetic antiferromagnets.

    PubMed

    Yu, Ziyang; Zhang, Yue; Zhang, Zhenhua; Cheng, Ming; Lu, Zhihong; Yang, Xiaofei; Shi, Jing; Xiong, Rui

    2018-04-27

    In this article, we present our numerical investigation about the spin-orbit-torque induced domain-wall (DW) motion in a synthetic antiferromagnetic multilayer nanotrack. This nanotrack was composed by two ferromagnetic (FM) layers with a RKKY inter-layer antiferromagnetic (AFM) exchange coupling. The velocity of DW was well manipulated by varying parameters including inter-layer exchange constant, the Dzyaloshinskii-Moriya interaction (DMI) strength, the current density and the magnetic anisotropy. The DW velocity was found to be strictly related to the orientation of the moments in the two FM layers. When the interlayer exchange constant or the DMI constant were larger than a critical value, there was a large angle between the moments in one FM layer and that in the other one under the current, and the DW was driven to move at an ultrahigh speed (around 10 000 m s -1 ). However, when the DMI or the AFM exchange coupling was weaker than the critical value, the moments in one FM layer were parallel to that in the other one under the current, and the velocity was significantly reduced.

  15. Myocardial wall thickening from gated magnetic resonance images using Laplace's equation

    NASA Astrophysics Data System (ADS)

    Prasad, M.; Ramesh, A.; Kavanagh, P.; Gerlach, J.; Germano, G.; Berman, D. S.; Slomka, P. J.

    2009-02-01

    The aim of our work is to present a robust 3D automated method for measuring regional myocardial thickening using cardiac magnetic resonance imaging (MRI) based on Laplace's equation. Multiple slices of the myocardium in short-axis orientation at end-diastolic and end-systolic phases were considered for this analysis. Automatically assigned 3D epicardial and endocardial boundaries were fitted to short-axis and long axis slices corrected for breathold related misregistration, and final boundaries were edited by a cardiologist if required. Myocardial thickness was quantified at the two cardiac phases by computing the distances between the myocardial boundaries over the entire volume using Laplace's equation. The distance between the surfaces was found by computing normalized gradients that form a vector field. The vector fields represent tangent vectors along field lines connecting both boundaries. 3D thickening measurements were transformed into polar map representation and 17-segment model (American Heart Association) regional thickening values were derived. The thickening results were then compared with standard 17-segment 6-point visual scoring of wall motion/wall thickening (0=normal; 5=greatest abnormality) performed by a consensus of two experienced imaging cardiologists. Preliminary results on eight subjects indicated a strong negative correlation (r=-0.8, p<0.0001) between the average thickening obtained using Laplace and the summed segmental visual scores. Additionally, quantitative ejection fraction measurements also correlated well with average thickening scores (r=0.72, p<0.0001). For segmental analysis, we obtained an overall correlation of -0.55 (p<0.0001) with higher agreement along the mid and apical regions (r=-0.6). In conclusion 3D Laplace transform can be used to quantify myocardial thickening in 3D.

  16. Trajectory of coronary motion and its significance in robotic motion cancellation.

    PubMed

    Cattin, Philippe; Dave, Hitendu; Grünenfelder, Jürg; Szekely, Gabor; Turina, Marko; Zünd, Gregor

    2004-05-01

    To characterize remaining coronary artery motion of beating pig hearts after stabilization with an 'Octopus' using an optical remote analysis technique. Three pigs (40, 60 and 65 kg) underwent full sternotomy after receiving general anesthesia. An 8-bit high speed black and white video camera (50 frames/s) coupled with a laser sensor (60 microm resolution) were used to capture heart wall motion in all three dimensions. Dopamine infusion was used to deliberately modulate cardiac contractility. Synchronized ECG, blood pressure, airway pressure and video data of the region around the first branching point of the left anterior descending (LAD) coronary artery after Octopus stabilization were captured for stretches of 8 s each. Several sequences of the same region were captured over a period of several minutes. Computerized off-line analysis allowed us to perform minute characterization of the heart wall motion. The movement of the points of interest on the LAD ranged from 0.22 to 0.81 mm in the lateral plane (x/y-axis) and 0.5-2.6 mm out of the plane (z-axis). Fast excursions (>50 microm/s in the lateral plane) occurred corresponding to the QRS complex and the T wave; while slow excursion phases (<50 microm/s in the lateral plane) were observed during the P wave and the ST segment. The trajectories of the points of interest during consecutive cardiac cycles as well as during cardiac cycles minutes apart remained comparable (the differences were negligible), provided the hemodynamics remained stable. Inotrope-induced changes in cardiac contractility influenced not only the maximum excursion, but also the shape of the trajectory. Normal positive pressure ventilation displacing the heart in the thoracic cage was evident by the displacement of the reference point of the trajectory. The movement of the coronary artery after stabilization appears to be still significant. Minute characterization of the trajectory of motion could provide the substrate for achieving motion

  17. Intermittent nature of acceleration in near wall turbulence.

    PubMed

    Lee, Changhoon; Yeo, Kyongmin; Choi, Jung-Il

    2004-04-09

    Using direct numerical simulation of a fully developed turbulent channel flow, we investigate the behavior of acceleration near a solid wall. We find that acceleration near the wall is highly intermittent and the intermittency is in large part associated with the near wall organized coherent turbulence structures. We also find that acceleration of large magnitude is mostly directed towards the rotation axis of the coherent vortical structures, indicating that the source of the intermittent acceleration is the rotational motion associated with the vortices that causes centripetal acceleration.

  18. On the theory of compliant wall drag reduction in turbulent boundary layers

    NASA Technical Reports Server (NTRS)

    Ash, R. L.

    1974-01-01

    A theoretical model has been developed which can explain how the motion of a compliant wall reduces turbulent skin friction drag. Available experimental evidence at low speeds has been used to infer that a compliant surface selectively removes energy from the upper frequency range of the energy containing eddies and through resulting surface motions can produce locally negative Reynolds stresses at the wall. The theory establishes a preliminary amplitude and frequency criterion as the basis for designing effective drag reducing compliant surfaces.

  19. An appraisal of the Functional Movement Screen™ grading criteria--Is the composite score sensitive to risky movement behavior?

    PubMed

    Frost, David M; Beach, Tyson A C; Campbell, Troy L; Callaghan, Jack P; McGill, Stuart M

    2015-11-01

    To examine the relationship between the composite Functional Movement Screen (FMS) score and performers' spine and frontal plane knee motion. Examined the spine and frontal plane knee motion exhibited by performers who received high (>14) and low (<14) composite FMS scores. Participants' body motions were quantified while they performed the FMS. Biomechanics laboratory. Twelve men who received composite FMS scores greater than 14 were assigned to a high-scoring group. Twelve age-, height- and weight-matched men with FMS scores below 14 were assigned to a low-scoring group. Composite FMS scores and peak lumbar spine flexion/extension, lateral bend and axial twist, and left and right frontal plane knee motion. Significant differences (p < 0.05) and large effect sizes (>0.8) were noted between the high- and low-scoring groups when performing the FMS tasks; high-scorers employed less spine and frontal plane knee motion. Substantial variation was also observed amongst participants. Participants with high composite FMS scores exhibited less spine and frontal plane knee motion while performing the FMS in comparison to their low-scoring counterparts. However, because substantial variation was observed amongst performers, the FMS may not provide the specificity needed for individualized injury risk assessment and exercise prescription. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Self-sustaining processes at all scales in wall-bounded turbulent shear flows

    PubMed Central

    Hwang, Yongyun

    2017-01-01

    We collect and discuss the results of our recent studies which show evidence of the existence of a whole family of self-sustaining motions in wall-bounded turbulent shear flows with scales ranging from those of buffer-layer streaks to those of large-scale and very-large-scale motions in the outer layer. The statistical and dynamical features of this family of self-sustaining motions, which are associated with streaks and quasi-streamwise vortices, are consistent with those of Townsend’s attached eddies. Motions at each relevant scale are able to sustain themselves in the absence of forcing from larger- or smaller-scale motions by extracting energy from the mean flow via a coherent lift-up effect. The coherent self-sustaining process is embedded in a set of invariant solutions of the filtered Navier–Stokes equations which take into full account the Reynolds stresses associated with the residual smaller-scale motions. This article is part of the themed issue ‘Toward the development of high-fidelity models of wall turbulence at large Reynolds number’. PMID:28167581

  1. Self-sustaining processes at all scales in wall-bounded turbulent shear flows.

    PubMed

    Cossu, Carlo; Hwang, Yongyun

    2017-03-13

    We collect and discuss the results of our recent studies which show evidence of the existence of a whole family of self-sustaining motions in wall-bounded turbulent shear flows with scales ranging from those of buffer-layer streaks to those of large-scale and very-large-scale motions in the outer layer. The statistical and dynamical features of this family of self-sustaining motions, which are associated with streaks and quasi-streamwise vortices, are consistent with those of Townsend's attached eddies. Motions at each relevant scale are able to sustain themselves in the absence of forcing from larger- or smaller-scale motions by extracting energy from the mean flow via a coherent lift-up effect. The coherent self-sustaining process is embedded in a set of invariant solutions of the filtered Navier-Stokes equations which take into full account the Reynolds stresses associated with the residual smaller-scale motions.This article is part of the themed issue 'Toward the development of high-fidelity models of wall turbulence at large Reynolds number'. © 2017 The Author(s).

  2. Velocity Enhancement by Synchronization of Magnetic Domain Walls

    NASA Astrophysics Data System (ADS)

    Hrabec, Aleš; Křižáková, Viola; Pizzini, Stefania; Sampaio, João; Thiaville, André; Rohart, Stanislas; Vogel, Jan

    2018-06-01

    Magnetic domain walls are objects whose dynamics is inseparably connected to their structure. In this Letter, we investigate magnetic bilayers, which are engineered such that a coupled pair of domain walls, one in each layer, is stabilized by a cooperation of Dzyaloshinskii-Moriya interaction and flux-closing mechanism. The dipolar field mediating the interaction between the two domain walls links not only their position but also their structure. We show that this link has a direct impact on their magnetic-field-induced dynamics. We demonstrate that in such a system the coupling leads to an increased domain wall velocity with respect to single domain walls. Since the domain wall dynamics is observed in a precessional regime, the dynamics involves the synchronization between the two walls to preserve the flux closure during motion. Properties of these coupled oscillating walls can be tuned by an additional in-plane magnetic field enabling a rich variety of states, from perfect synchronization to complete detuning.

  3. A novel approach to simulate chest wall micro-motion for bio-radar life detection purpose

    NASA Astrophysics Data System (ADS)

    An, Qiang; Li, Zhao; Liang, Fulai; Chen, Fuming; Wang, Jianqi

    2016-10-01

    Volunteers are often recruited to serve as the detection targets during the research process of bio-radar life detection technology, in which the experiment results are highly susceptible to the physical status of different individuals (shape, posture, etc.). In order to objectively evaluate the radar system performance and life detection algorithms, a standard detection target is urgently needed. The paper first proposed a parameter quantitatively controllable system to simulate the chest wall micro-motion caused mainly by breathing and heart beating. Then, the paper continued to analyze the material and size selection of the scattering body mounted on the simulation system from the perspective of back scattering energy. The computational electromagnetic method was employed to determine the exact scattering body. Finally, on-site experiments were carried out to verify the reliability of the simulation platform utilizing an IR UWB bioradar. Experimental result shows that the proposed system can simulate a real human target from three aspects: respiration frequency, amplitude and body surface scattering energy. Thus, it can be utilized as a substitute for a human target in radar based non-contact life detection research in various scenarios.

  4. Fast switching and signature of efficient domain wall motion driven by spin-orbit torques in a perpendicular anisotropy magnetic insulator/Pt bilayer

    NASA Astrophysics Data System (ADS)

    Avci, Can Onur; Rosenberg, Ethan; Baumgartner, Manuel; Beran, Lukáš; Quindeau, Andy; Gambardella, Pietro; Ross, Caroline A.; Beach, Geoffrey S. D.

    2017-08-01

    We report fast and efficient current-induced switching of a perpendicular anisotropy magnetic insulator thulium iron garnet by using spin-orbit torques (SOT) from the Pt overlayer. We first show that, with quasi-DC (10 ms) current pulses, SOT-induced switching can be achieved with an external field as low as 2 Oe, making TmIG an outstanding candidate to realize efficient switching in heterostructures that produce moderate stray fields without requiring an external field. We then demonstrate deterministic switching with fast current pulses (≤20 ns) with an amplitude of ˜1012 A/m2, similar to all-metallic structures. We reveal that, in the presence of an initially nucleated domain, the critical switching current is reduced by up to a factor of five with respect to the fully saturated initial state, implying efficient current-driven domain wall motion in this system. Based on measurements with 2 ns-long pulses, we estimate the domain wall velocity of the order of ˜400 m/s per j = 1012 A/m2.

  5. Domain wall dynamics driven by spin transfer torque and the spin-orbit field.

    PubMed

    Hayashi, Masamitsu; Nakatani, Yoshinobu; Fukami, Shunsuke; Yamanouchi, Michihiko; Mitani, Seiji; Ohno, Hideo

    2012-01-18

    We have studied current-driven dynamics of domain walls when an in-plane magnetic field is present in perpendicularly magnetized nanowires using an analytical model and micromagnetic simulations. We model an experimentally studied system, ultrathin magnetic nanowires with perpendicular anisotropy, where an effective in-plane magnetic field is developed when current is passed along the nanowire due to the Rashba-like spin-orbit coupling. Using a one-dimensional model of a domain wall together with micromagnetic simulations, we show that the existence of such in-plane magnetic fields can either lower or raise the threshold current needed to cause domain wall motion. In the presence of the in-plane field, the threshold current differs for positive and negative currents for a given wall chirality, and the wall motion becomes sensitive to out-of-plane magnetic fields. We show that large non-adiabatic spin torque can counteract the effect of the in-plane field.

  6. Brownian motion of tethered nanowires.

    PubMed

    Ota, Sadao; Li, Tongcang; Li, Yimin; Ye, Ziliang; Labno, Anna; Yin, Xiaobo; Alam, Mohammad-Reza; Zhang, Xiang

    2014-05-01

    Brownian motion of slender particles near a boundary is ubiquitous in biological systems and in nanomaterial assembly, but the complex hydrodynamic interaction in those systems is still poorly understood. Here, we report experimental and computational studies of the Brownian motion of silicon nanowires tethered on a substrate. An optical interference method enabled direct observation of microscopic rotations of the slender bodies in three dimensions with high angular and temporal resolutions. This quantitative observation revealed anisotropic and angle-dependent hydrodynamic wall effects: rotational diffusivity in inclined and azimuth directions follows different power laws as a function of the length, ∼ L(-2.5) and ∼ L(-3), respectively, and is more hindered for smaller inclined angles. In parallel, we developed an implicit simulation technique that takes the complex wire-wall hydrodynamic interactions into account efficiently, the result of which agreed well with the experimentally observed angle-dependent diffusion. The demonstrated techniques provide a platform for studying the microrheology of soft condensed matters, such as colloidal and biological systems near interfaces, and exploring the optimal self-assembly conditions of nanostructures.

  7. Atlas-Based Ventricular Shape Analysis for Understanding Congenital Heart Disease.

    PubMed

    Farrar, Genevieve; Suinesiaputra, Avan; Gilbert, Kathleen; Perry, James C; Hegde, Sanjeet; Marsden, Alison; Young, Alistair A; Omens, Jeffrey H; McCulloch, Andrew D

    2016-12-01

    Congenital heart disease is associated with abnormal ventricular shape that can affect wall mechanics and may be predictive of long-term adverse outcomes. Atlas-based parametric shape analysis was used to analyze ventricular geometries of eight adolescent or adult single-ventricle CHD patients with tricuspid atresia and Fontans. These patients were compared with an "atlas" of non-congenital asymptomatic volunteers, resulting in a set of z-scores which quantify deviations from the control population distribution on a patient-by-patient basis. We examined the potential of these scores to: (1) quantify abnormalities of ventricular geometry in single ventricle physiologies relative to the normal population; (2) comprehensively quantify wall motion in CHD patients; and (3) identify possible relationships between ventricular shape and wall motion that may reflect underlying functional defects or remodeling in CHD patients. CHD ventricular geometries at end-diastole and end-systole were individually compared with statistical shape properties of an asymptomatic population from the Cardiac Atlas Project. Shape analysis-derived model properties, and myocardial wall motions between end-diastole and end-systole, were compared with physician observations of clinical functional parameters. Relationships between altered shape and altered function were evaluated via correlations between atlas-based shape and wall motion scores. Atlas-based shape analysis identified a diverse set of specific quantifiable abnormalities in ventricular geometry or myocardial wall motion in all subjects. Moreover, this initial cohort displayed significant relationships between specific shape abnormalities such as increased ventricular sphericity and functional defects in myocardial deformation, such as decreased long-axis wall motion. These findings suggest that atlas-based ventricular shape analysis may be a useful new tool in the management of patients with CHD who are at risk of impaired ventricular

  8. Algebraic motion of vertically displacing plasmas

    NASA Astrophysics Data System (ADS)

    Pfefferlé, D.; Bhattacharjee, A.

    2018-02-01

    The vertical motion of a tokamak plasma is analytically modelled during its non-linear phase by a free-moving current-carrying rod inductively coupled to a set of fixed conducting wires or a cylindrical conducting shell. The solutions capture the leading term in a Taylor expansion of the Green's function for the interaction between the plasma column and the surrounding vacuum vessel. The plasma shape and profiles are assumed not to vary during the vertical drifting phase such that the plasma column behaves as a rigid body. In the limit of perfectly conducting structures, the plasma is prevented to come in contact with the wall due to steep effective potential barriers created by the induced Eddy currents. Resistivity in the wall allows the equilibrium point to drift towards the vessel on the slow timescale of flux penetration. The initial exponential motion of the plasma, understood as a resistive vertical instability, is succeeded by a non-linear "sinking" behaviour shown to be algebraic and decelerating. The acceleration of the plasma column often observed in experiments is thus concluded to originate from an early sharing of toroidal current between the core, the halo plasma, and the wall or from the thermal quench dynamics precipitating loss of plasma current.

  9. Domain wall motion in magnetically frustrated nanorings

    NASA Astrophysics Data System (ADS)

    Lubarda, M. V.; Escobar, M. A.; Li, S.; Chang, R.; Fullerton, E. E.; Lomakin, V.

    2012-06-01

    We describe a magnetically frustrated nanoring (MFNR) configuration which is formed by introducing antiferromagnetic coupling across an interface orthogonal to the ring's circumferential direction. Such structures have the unique characteristic that only one itinerant domain wall (DW) can exist in the ring, which does not need to be nucleated or injected into the structure and can never escape making it analogous to a magnetic Möbius strip. Numerical simulations show that the DW in a MFNR can be driven consecutively around the ring with a prescribed cyclicity, and that the frequency of revolutions can be controlled by the applied field. The energy landscapes can be controlled to be flat allowing for low fields of operation or to have a barrier for thermal stability. Potential logic and memory applications of MFNRs are considered and discussed.

  10. Shock Tunnel Tests of Arched Wall Panels

    DTIC Science & Technology

    1974-07-01

    NCNOR « LOT S/W ETC lOLT ANCMO« NOO IEE DETAIL* / tELOW , , METAL TIE* / I*" 0. C. VERT -HAiONRT «ALL...same as shown in Table 2-1. 2-6 m^ Table 2-1 SPACING OF WALL TIES i Moiimuffl Dittonc« Moiimum Spocing ef No 4 Gogt Wall Typ. I K«twHn Lot ...sides free to move), the flexural cracking occurs at the top, botton \\ and center, and the resistance to motion, induced by ’ wedging"or geometric

  11. Self-propelled colloidal particle near a planar wall: A Brownian dynamics study

    NASA Astrophysics Data System (ADS)

    Mozaffari, Ali; Sharifi-Mood, Nima; Koplik, Joel; Maldarelli, Charles

    2018-01-01

    Miniaturized, self-propelled locomotors use chemo-mechanical transduction mechanisms to convert fuel in the environment to autonomous motion. Recent experimental and theoretical studies demonstrate that these autonomous engines can passively follow the contours of solid boundaries they encounter. Boundary guidance, however, is not necessarily stable: Mechanical disturbances can cause the motor to hydrodynamically depart from the passively guided pathway. Furthermore, given the scaled-down size of micromotors (typically 100 nm to10 μ m ), Brownian thermal fluctuation forces are necessarily important, and these stochastic forces can randomize passively steered trajectories. Here we examine theoretically the stability of boundary-guided motion of micromotors along infinite planar walls to mechanical disturbances and to Brownian forces. Our aim is to understand under what conditions this passively guided motion is stable. We choose a locomotor design in which spherical colloids are partially coated with a catalytic cap that reacts with solute to produce a product. The product is repelled from the particle surface, causing the particle to move with the inert face at the front (autonomous motion via self-diffusiophoresis). When propelled towards a planar wall, deterministic hydrodynamic studies demonstrate that these locomotors can exhibit, for large enough cap sizes, steady trajectories in which the particle either skims unidirectionally along the surface at a constant distance from the wall or becomes stationary. We first investigate the linear hydrodynamic stability of these states by expanding the equations of motion about the states, and we find that linear perturbations decay exponentially in time. We then study the effects of thermal fluctuations by formulating a Langevin equation for the particle motion which includes the Brownian stochastic force. The Péclet number scales the ratio of deterministic to Brownian forces, where Pe =π μ a2v˜c/kBT and a denotes

  12. Domain wall motion and electromechanical strain in lead-free piezoelectrics: Insight from the model system (1 - x)Ba(Zr 0.2Ti 0.8)O 3-x(Ba 0.7Ca 0.3)TiO 3 using in situ high-energy X-ray diffraction during application of electric fields

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tutuncu, Goknur; Li, Binzhi; Bowman, Keith

    The piezoelectric compositions (1 - x)Ba(Zr 0.2Ti 0.8)O 3–x(Ba 0.7Ca 0.3)TiO 3 (BZT-xBCT) span a model lead-free morphotropic phase boundary (MPB) between room temperature rhombohedral and tetragonal phases at approximately x = 0.5. In the present work, in situ X-ray diffraction measurements during electric field application are used to elucidate the origin of electromechanical strain in several compositions spanning the tetragonal compositional range 0.6 ≤ x ≤ 0.9. As BCT concentration decreases towards the MPB, the tetragonal distortion (given by c/a-1) decreases concomitantly with an increase in 90° domain wall motion. The increase in observed macroscopic strain is predominantly attributedmore » to the increased contribution from 90° domain wall motion. The results demonstrate that domain wall motion is a significant factor in achieving high strain and piezoelectric coefficients in lead-free polycrystalline piezoelectrics.« less

  13. Physical Sensing of Surface Properties by Microswimmers--Directing Bacterial Motion via Wall Slip.

    PubMed

    Hu, Jinglei; Wysocki, Adam; Winkler, Roland G; Gompper, Gerhard

    2015-05-20

    Bacteria such as Escherichia coli swim along circular trajectories adjacent to surfaces. Thereby, the orientation (clockwise, counterclockwise) and the curvature depend on the surface properties. We employ mesoscale hydrodynamic simulations of a mechano-elastic model of E. coli, with a spherocylindrical body propelled by a bundle of rotating helical flagella, to study quantitatively the curvature of the appearing circular trajectories. We demonstrate that the cell is sensitive to nanoscale changes in the surface slip length. The results are employed to propose a novel approach to directing bacterial motion on striped surfaces with different slip lengths, which implies a transformation of the circular motion into a snaking motion along the stripe boundaries. The feasibility of this approach is demonstrated by a simulation of active Brownian rods, which also reveals a dependence of directional motion on the stripe width.

  14. Improvement of cardiac CT reconstruction using local motion vector fields.

    PubMed

    Schirra, Carsten Oliver; Bontus, Claas; van Stevendaal, Udo; Dössel, Olaf; Grass, Michael

    2009-03-01

    The motion of the heart is a major challenge for cardiac imaging using CT. A novel approach to decrease motion blur and to improve the signal to noise ratio is motion compensated reconstruction which takes motion vector fields into account in order to correct motion. The presented work deals with the determination of local motion vector fields from high contrast objects and their utilization within motion compensated filtered back projection reconstruction. Image registration is applied during the quiescent cardiac phases. Temporal interpolation in parameter space is used in order to estimate motion during strong motion phases. The resulting motion vector fields are during image reconstruction. The method is assessed using a software phantom and several clinical cases for calcium scoring. As a criterion for reconstruction quality, calcium volume scores were derived from both, gated cardiac reconstruction and motion compensated reconstruction throughout the cardiac phases using low pitch helical cone beam CT acquisitions. The presented technique is a robust method to determine and utilize local motion vector fields. Motion compensated reconstruction using the derived motion vector fields leads to superior image quality compared to gated reconstruction. As a result, the gating window can be enlarged significantly, resulting in increased SNR, while reliable Hounsfield units are achieved due to the reduced level of motion artefacts. The enlargement of the gating window can be translated into reduced dose requirements.

  15. The contribution of 180° domain wall motion to dielectric properties quantified from in situ X-ray diffraction

    DOE PAGES

    Fancher, C. M.; Brewer, S.; Chung, C. C.; ...

    2016-12-27

    Here, the contribution of 180° domain wall motion to polarization and dielectric properties of ferroelectric materials has yet to be determined experimentally. In this paper, an approach for estimating the extent of (180°) domain reversal during application of electric fields is presented. We demonstrate this method by determining the contribution of domain reversal to polarization in soft lead zirconate titanate during application of strong electric fields. At the maximum applied field, domain reversal was determined to account for >80% of the measured macroscopic polarization. We also apply the method to quantify the contribution of domain reversal to the weak-field dielectricmore » permittivity of BaTiO 3. The results of this analysis determined that domain reversal accounts for up to ~70% of the macroscopic dielectric permittivity in BaTiO 3. These results demonstrate the predominance of domain reversal to high and low-field dielectric response in ferroelectric polycrystalline materials.« less

  16. The contribution of 180° domain wall motion to dielectric properties quantified from in situ X-ray diffraction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fancher, C. M.; Brewer, S.; Chung, C. C.

    2017-03-01

    The contribution of 180° domain wall motion to polarization and dielectric properties of ferroelectric materials has yet to be determined experimentally. In this paper, an approach for estimating the extent of (180°) domain reversal during application of electric fields is presented. We demonstrate this method by determining the contribution of domain reversal to polarization in soft lead zirconate titanate during application of strong electric fields. At the maximum applied field, domain reversal was determined to account for >80% of the measured macroscopic polarization. We also apply the method to quantify the contribution of domain reversal to the weak-field dielectric permittivitymore » of BaTiO 3. The results of this analysis determined that domain reversal accounts for up to ~70% of the macroscopic dielectric permittivity in BaTiO 3. These results demonstrate the predominance of domain reversal to high and low-field dielectric response in ferroelectric polycrystalline materials.« less

  17. Ratchet Effects and Domain Wall Energy Landscapes in Amorphous Magnetic Films with 2D Arrays of Asymmetric Holes

    NASA Astrophysics Data System (ADS)

    Martin, J. I.; Alija, A.; Sobrado, I.; Perez-Junquera, A.; Rodriguez-Rodriguez, G.; Velez, M.; Alameda, J. M.; Marconi, V. I.; Kolton, A. B.; Parrondo, J. M. R.

    2009-03-01

    The driven motion of domain walls in extended magnetic films patterned with 2D arrays of asymmetric holes has been found to be subject to two different crossed ratchet effects [1] which results in an inversion of the sign of domain wall motion rectification as a function of the applied magnetic field. This effect can be understood in terms of the competition between drive, elasticity and asymmetric pinning as revealed by a simple 4̂-model. In order to optimize the asymmetric hole design, the relevant energy landscapes for domain wall motion across the array of asymmetric holes have been calculated by micromagnetic simulations as a function of array geometrical characteristics. The effects of a transverse magnetic field on these two crossed ratchet effects will also be discussed in terms of the decrease in domain wall energy per unit area and of the modifications in the magnetostatic barriers for domain wall pinning at the asymmetric inclusions. Work supported by Spanish MICINN.[1] A. Perez-Junquera et al, Phys. Rev. Lett. 100 (2008) 037203

  18. Excess velocity of magnetic domain walls close to the depinning field

    NASA Astrophysics Data System (ADS)

    Caballero, Nirvana B.; Fernández Aguirre, Iván; Albornoz, Lucas J.; Kolton, Alejandro B.; Rojas-Sánchez, Juan Carlos; Collin, Sophie; George, Jean Marie; Diaz Pardo, Rebeca; Jeudy, Vincent; Bustingorry, Sebastian; Curiale, Javier

    2017-12-01

    Magnetic field driven domain wall velocities in [Co/Ni] based multilayers thin films have been measured using polar magneto-optic Kerr effect microscopy. The low field results are shown to be consistent with the universal creep regime of domain wall motion, characterized by a stretched exponential growth of the velocity with the inverse of the applied field. Approaching the depinning field from below results in an unexpected excess velocity with respect to the creep law. We analyze these results using scaling theory to show that this speeding up of domain wall motion can be interpreted as due to the increase of the size of the deterministic relaxation close to the depinning transition. We propose a phenomenological model to accurately fit the observed excess velocity and to obtain characteristic values for the depinning field Hd, the depinning temperature Td, and the characteristic velocity scale v0 for each sample.

  19. A mechanical simulator of cardiac wall kinematics.

    PubMed

    Cutrì, Elena; Bagnoli, Paola; Marcelli, Emanuela; Biondi, Federico; Cercenelli, Laura; Costantino, Maria Laura; Plicchi, Gianni; Fumero, Roberto

    2010-01-01

    Aim of this study is to develop a mechanical simulator (MS) reproducing cardiac wall kinematics [i.e., radial (R), longitudinal (L) and rotational (RT) motions] to test piezoelectric gyroscopic sensors (GS) that are able to measure cardiac torsion that has proved to be a sensitive index of cardiac performance. The MS consists of three brushless motors controlled by a dedicated software either separately or simultaneously reproducing the three main cardiac wall movements (R, L, RT) obtained by implementing different physiologic or pathologic velocity profiles derived from in vivo data. GS accuracy (max % error) was experimentally tested by connecting it to the MS driven in velocity in different working conditions [i.e., cardiac period (515-1030 ms), RT angle (4-16 degrees), GS axis inclination (0-90 degrees) with respect to the cardiac rotation axis]. The MS reproduced the tested velocity profiles well. The GS showed high accuracy in measuring both physiologic and pathologic RT velocity profiles, whereas they proved insensitive to R and L motions. GS axis inclination influenced measurements; however, it was possible to correct this taking the inclination angle cosine into account. The MS proved to be a useful tool to study cardiac wall kinematics and test GS reliability with a view to in vivo application.

  20. Motion sickness prevalence in school children.

    PubMed

    Henriques, Isadora Ferreira; Douglas de Oliveira, Dhelfeson Willya; Oliveira-Ferreira, Fernanda; Andrade, Peterson M O

    2014-11-01

    This study aimed to determine the prevalence of motion sickness in schoolchildren and related the finding to the postural balance and quality of life. A population-based cross-sectional study was carried out with 831 children aged 7 to 12 years. The frequency of motion sickness was evaluated based on the Motion Sickness Susceptibility Questionnaire-Short (MSSQ-short). Postural balance was assessed using the Romberg test under different sensory conditions. The Dizziness Handicap Inventory was used in order to assess the quality of life. The statistical analyses were performed using the chi-square, Kruskal-Wallis, Mann-Whitney, and Spearman correlation tests. The prevalence of motion sickness was 43.4 % in car, 43.2 % on bus, 11.7 % on park swing, and 11.6 % on Ferris wheel. Mean unadjusted scores on the MSSQ-short ranged from 5.0 (SE = 0.5) for 10-year-olds to 6.8 (SE = 0.5) for 9-year-olds. The most prevalent symptoms following the balance tests were dizziness (89.2 %), vertigo (54.9 %), headache (10.6 %), and nausea (8.2 %). Significant correlations were found between the MSSQ-short score and all postural balance tests. Significant correlations were found between the MSSQ and modified DHI (Dizziness Handicap Inventory) at all ages. The prevalence of motion sickness in schoolchildren is greater when in a car or on a bus. An association was found between motion sickness and postural balance tests and motion sickness and quality of life.

  1. Global motion perception is associated with motor function in 2-year-old children.

    PubMed

    Thompson, Benjamin; McKinlay, Christopher J D; Chakraborty, Arijit; Anstice, Nicola S; Jacobs, Robert J; Paudel, Nabin; Yu, Tzu-Ying; Ansell, Judith M; Wouldes, Trecia A; Harding, Jane E

    2017-09-29

    The dorsal visual processing stream that includes V1, motion sensitive area V5 and the posterior parietal lobe, supports visually guided motor function. Two recent studies have reported associations between global motion perception, a behavioural measure of processing in V5, and motor function in pre-school and school aged children. This indicates a relationship between visual and motor development and also supports the use of global motion perception to assess overall dorsal stream function in studies of human neurodevelopment. We investigated whether associations between vision and motor function were present at 2 years of age, a substantially earlier stage of development. The Bayley III test of Infant and Toddler Development and measures of vision including visual acuity (Cardiff Acuity Cards), stereopsis (Lang stereotest) and global motion perception were attempted in 404 2-year-old children (±4 weeks). Global motion perception (quantified as a motion coherence threshold) was assessed by observing optokinetic nystagmus in response to random dot kinematograms of varying coherence. Linear regression revealed that global motion perception was modestly, but statistically significantly associated with Bayley III composite motor (r 2 =0.06, P<0.001, n=375) and gross motor scores (r 2 =0.06, p<0.001, n=375). The associations remained significant when language score was included in the regression model. In addition, when language score was included in the model, stereopsis was significantly associated with composite motor and fine motor scores, but unaided visual acuity was not statistically significantly associated with any of the motor scores. These results demonstrate that global motion perception and binocular vision are associated with motor function at an early stage of development. Global motion perception can be used as a partial measure of dorsal stream function from early childhood. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Universal current-velocity relation of skyrmion motion in chiral magnets

    NASA Astrophysics Data System (ADS)

    Iwasaki, Junichi; Mochizuki, Masahito; Nagaosa, Naoto

    2013-02-01

    Current-driven motion of the magnetic domain wall in ferromagnets is attracting intense attention because of potential applications such as racetrack memory. There, the critical current density to drive the motion is ~109-1012 A m-2. The skyrmions recently discovered in chiral magnets have much smaller critical current density of ~105-106 A m-2, but the microscopic mechanism is not yet explored. Here we present a numerical simulation of Landau-Lifshitz-Gilbert equation, which reveals a remarkably robust and universal current-velocity relation of the skyrmion motion driven by the spin-transfer-torque unaffected by either impurities or nonadiabatic effect in sharp contrast to the case of domain wall or spin helix. Simulation results are analysed using a theory based on Thiele’s equation, and it is concluded that this behaviour is due to the Magnus force and flexible shape-deformation of individual skyrmions and skyrmion crystal, which enable them to avoid pinning centres.

  3. Shoulder kinematics during the wall push-up plus exercise.

    PubMed

    Lunden, Jason B; Braman, Jonathan P; Laprade, Robert F; Ludewig, Paula M

    2010-03-01

    The push-up plus exercise is a common therapeutic exercise for improving shoulder function and treating shoulder pathology. To date, the kinematics of the push-up plus exercise have not been studied. Our hypothesis was that the wall push-up plus exercise would demonstrate increased scapular internal rotation and increased humeral anterior translation during the plus phase of the exercise, thereby potentially impacting the subacromial space. Bone pins were inserted in the humerus and scapula in 12 healthy volunteers with no history of shoulder pathology. In vivo motion during the wall push-up plus exercise was tracked using an electromagnetic tracking system. During the wall push-up plus exercise, from a starting position to the push-up plus position, there was a significant increase in scapular downward rotation (P < .05) and internal rotation (P < .05). The pattern of glenohumeral motion was humeral elevation (P < .05) and movement anterior to the scapular plane (P < .05), with humeral external rotation remaining relatively constant. We found that during a wall push-up plus exercise in healthy volunteers, the scapula was placed in a position potentially associated with shoulder impingement. Because of the shoulder kinematics of the wall push-up plus exercise, utilization of this exercise without modification early on in shoulder rehabilitation, especially in patients with subacromial impingement, should be considered cautiously. Copyright 2010 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Mosby, Inc. All rights reserved.

  4. Evaluating MRI based vascular wall motion as a biomarker of Fontan hemodynamic performance

    NASA Astrophysics Data System (ADS)

    Menon, Prahlad G.; Hong, Haifa

    2015-03-01

    The Fontan procedure for single-ventricle heart disease involves creation of pathways to divert venous blood from the superior & inferior venacavae (SVC, IVC) directly into the pulmonary arteries (PA), bypassing the right ventricle. For optimal surgical outcomes, venous flow energy loss in the resulting vascular construction must be minimized and ensuring close to equal flow distribution from the Fontan conduit connecting IVC to the left & right PA is paramount. This requires patient-specific hemodynamic evaluation using computational fluid dynamics (CFD) simulations which are often time and resource intensive, limiting applicability for real-time patient management in the clinic. In this study, we report preliminary efforts at identifying a new non-invasive imaging based surrogate for CFD simulated hemodynamics. We establish correlations between computed hemodynamic criteria from CFD modeling and cumulative wall displacement characteristics of the Fontan conduit quantified from cine cardiovascular MRI segmentations over time (i.e. 20 cardiac phases gated from the start of ventricular systole), in 5 unique Fontan surgical connections. To focus our attention on diameter variations while discounting side-to-side swaying motion of the Fontan conduit, the difference between its instantaneous regional expansion and inward contraction (averaged across the conduit) was computed and analyzed. Maximum Fontan conduit-average expansion over the cardiac cycle correlated with the anatomy-specific diametric offset between the axis of the IVC and SVC (r2=0.13, p=0.55) - a known factor correlated with Fontan energy loss and IVC-to-PA flow distribution. Investigation in a larger study cohort is needed to establish stronger statistical correlations.

  5. [Evaluation of left ventricular perfusion and regional wall motion in myocardial infarction: using 201Tl myocardial SPECT and 99mTc-HSAD multigated cardiac blood pool emission computed tomography].

    PubMed

    Nanjyo, S

    1994-09-01

    In order to evaluate left ventricular regional wall motion and regional myocardial perfusion, 99mTc-HSAD multigated cardiac blood pool emission computed tomography (cardiac pool SPECT) and 201Tl myocardial SPECT (Tl) were performed on 12 patients with acute myocardial infarction (AMI), 6 patients had treated with only thrombolysis in group I and 6 patients had treated with thrombolysis and selective PTCA in group II, 17 patients with old myocardial infarction (OMI) in group III and 5 normal volunteers (controls). The relationship between left ventricular regional wall motion and regional myocardial perfusion was estimated. The relationship between % length shortening (%LS) by cardiac pool SPECT and %Tl uptake (%TU) was good (r = 0.820) in group III. The value for %TU in the segments of akinesia was low (35%) and in the those of severe hypokinesia was higher (48%). In all phases, two groups showed significant relationships between %LS and %TU in group I and II. The %TU was unchanged in the akinetic segment, the %LS changed 30% in group I and the %LS changed to 49% in group II. If the %TU is more than 50% (AMI) or 40% (OMI), we would observe viable muscle. The combination of Tl and cardiac pool SPECT are useful for evaluating myocardial viability in the patients with AMI.

  6. Algebraic motion of vertically displacing plasmas

    DOE PAGES

    Pfefferle, D.; Bhattacharjee, A.

    2018-02-27

    In this paper, the vertical motion of a tokamak plasma is analytically modelled during its non-linear phase by a free-moving current-carrying rod inductively coupled to a set of fixed conducting wires or a cylindrical conducting shell. The solutions capture the leading term in a Taylor expansion of the Green's function for the interaction between the plasma column and the surrounding vacuum vessel. The plasma shape and profiles are assumed not to vary during the vertical drifting phase such that the plasma column behaves as a rigid body. In the limit of perfectly conducting structures, the plasma is prevented to comemore » in contact with the wall due to steep effective potential barriers created by the induced Eddy currents. Resistivity in the wall allows the equilibrium point to drift towards the vessel on the slow timescale of flux penetration. The initial exponential motion of the plasma, understood as a resistive vertical instability, is succeeded by a non-linear “sinking” behaviour shown to be algebraic and decelerating. Finally, the acceleration of the plasma column often observed in experiments is thus concluded to originate from an early sharing of toroidal current between the core, the halo plasma, and the wall or from the thermal quench dynamics precipitating loss of plasma current.« less

  7. Algebraic motion of vertically displacing plasmas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pfefferle, D.; Bhattacharjee, A.

    In this paper, the vertical motion of a tokamak plasma is analytically modelled during its non-linear phase by a free-moving current-carrying rod inductively coupled to a set of fixed conducting wires or a cylindrical conducting shell. The solutions capture the leading term in a Taylor expansion of the Green's function for the interaction between the plasma column and the surrounding vacuum vessel. The plasma shape and profiles are assumed not to vary during the vertical drifting phase such that the plasma column behaves as a rigid body. In the limit of perfectly conducting structures, the plasma is prevented to comemore » in contact with the wall due to steep effective potential barriers created by the induced Eddy currents. Resistivity in the wall allows the equilibrium point to drift towards the vessel on the slow timescale of flux penetration. The initial exponential motion of the plasma, understood as a resistive vertical instability, is succeeded by a non-linear “sinking” behaviour shown to be algebraic and decelerating. Finally, the acceleration of the plasma column often observed in experiments is thus concluded to originate from an early sharing of toroidal current between the core, the halo plasma, and the wall or from the thermal quench dynamics precipitating loss of plasma current.« less

  8. Analysis of secondary motions in square duct flow

    NASA Astrophysics Data System (ADS)

    Modesti, Davide; Pirozzoli, Sergio; Orlandi, Paolo; Grasso, Francesco

    2018-04-01

    We carry out direct numerical simulations (DNS) of square duct flow spanning the friction Reynolds number range {Re}τ * =150-1055, to study the nature and the role of secondary motions. We preliminarily find that secondary motions are not the mere result of the time averaging procedure, but rather they are present in the instantaneous flow realizations, corresponding to large eddies persistent in both space and time. Numerical experiments have also been carried out whereby the secondary motions are suppressed, hence allowing to quantifying their effect on the mean flow field. At sufficiently high Reynolds number, secondary motions are found to increase the friction coefficient by about 3%, hence proportionally to their relative strength with respect to the bulk flow. Simulations without secondary motions are found to yield larger deviations on the mean velocity profiles from the standard law-of-the-wall, revealing that secondary motions act as a self-regulating mechanism of turbulence whereby the effect of the corners is mitigated.

  9. Earthquake Resilient Tall Reinforced Concrete Buildings at Near-Fault Sites Using Base Isolation and Rocking Core Walls

    NASA Astrophysics Data System (ADS)

    Calugaru, Vladimir

    This dissertation pursues three main objectives: (1) to investigate the seismic response of tall reinforced concrete core wall buildings, designed following current building codes, subjected to pulse type near-fault ground motion, with special focus on the relation between the characteristics of the ground motion and the higher-modes of response; (2) to determine the characteristics of a base isolation system that results in nominally elastic response of the superstructure of a tall reinforced concrete core wall building at the maximum considered earthquake level of shaking; and (3) to demonstrate that the seismic performance, cost, and constructability of a base-isolated tall reinforced concrete core wall building can be significantly improved by incorporating a rocking core-wall in the design. First, this dissertation investigates the seismic response of tall cantilever wall buildings subjected to pulse type ground motion, with special focus on the relation between the characteristics of ground motion and the higher-modes of response. Buildings 10, 20, and 40 stories high were designed such that inelastic deformation was concentrated at a single flexural plastic hinge at their base. Using nonlinear response history analysis, the buildings were subjected to near-fault seismic ground motions as well as simple close-form pulses, which represented distinct pulses within the ground motions. Euler-Bernoulli beam models with lumped mass and lumped plasticity were used to model the buildings. Next, this dissertation investigates numerically the seismic response of six seismically base-isolated (BI) 20-story reinforced concrete buildings and compares their response to that of a fixed-base (FB) building with a similar structural system above ground. Located in Berkeley, California, 2 km from the Hayward fault, the buildings are designed with a core wall that provides most of the lateral force resistance above ground. For the BI buildings, the following are investigated

  10. Advanced age does not affect abdominal wall reconstruction outcomes using acellular dermal matrix: A comparative study using propensity score analysis.

    PubMed

    Giordano, Salvatore; Schaverien, Mark; Garvey, Patrick B; Baumann, Donald P; Liu, Jun; Butler, Charles E

    2017-06-01

    We hypothesized that elderly patients (≥65 years) experience worse outcomes following abdominal wall reconstruction (AWR) for hernia or oncologic resection. We included all consecutive patients who underwent complex AWR using acellular dermal matrix (ADM) between 2005 and 2015. Propensity score analysis was performed for risk adjustment in multivariable analysis and for one-to-one matching. The primary outcome was hernia recurrence; the secondary outcomes included surgical site occurrence (SSO) and bulging. Mean follow-up for the 511 patients was 31.4 months; 184 (36%) patients were elderly. The elderly and non-elderly groups had similar rates of hernia recurrence (7.6% vs 10.1%, respectively; p = 0.43) and SSO (24.5% vs 23.5%, respectively; p = 0.82). Bulging occurred significantly more often in elderly patients (6.5% vs 2.8%, respectively; p = 0.04). After adjustment through the propensity score, which included 130 pairs, these results persisted. Contrary to our hypothesis, elderly patients did not have worse outcomes in AWR with ADM. Surgeons should not deny elderly patients AWR solely because of their age. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Domain wall motion in sub-100 nm magnetic wire

    NASA Astrophysics Data System (ADS)

    Siddiqui, Saima; Dutta, Sumit; Currivan, Jean Anne; Ross, Caroline; Baldo, Marc

    2015-03-01

    Nonvolatile memory devices such as racetrack memory rely on the manipulation of domain wall (DW) in magnetic nanowires, and scaling of these devices requires an understanding of domain wall behavior as a function of the wire width. Due to the increased importance of edge roughness and magnetostatic interaction, DW pinning increases dramatically as the wire dimensions decrease and stochastic behavior is expected depending on the distribution of pinning sites. We report on the field driven DW statistics in sub-100 nm wide nanowires made from Co films with very small edge roughness. The nanowires were patterned in the form of a set of concentric rings of 10 μm diameter. Two different width nanowires with two different spacings have been studied. The rings were first saturated in plane to produce onion states and then the DWs were translated in the wires using an orthogonal in-plane field. The position of the DWs in the nanowires was determined with magnetic force microscopy. From the positions of the DWs in the nanowires, the strength of the extrinsic pinning sites was identified and they follow two different distributions in two different types of nanowire rings. For the closely spaced wires, magnetostatic interactions led to correlated movement of DWs in neighboring wires. The implications of DW pinning and interaction in nanoscale DW devices will be discussed.

  12. Impact of a drop onto a wetted wall: description of crown formation and propagation

    NASA Astrophysics Data System (ADS)

    Roisman, I. V.; Tropea, C.

    2002-12-01

    The impact of a drop onto a liquid film with a relatively high impact velocity, leading to the formation of a crown-like ejection, is studied theoretically. The motion of a kinematic discontinuity in the liquid film on the wall due to the drop impact, the formation of the upward jet at this kinematic discontinuity and its elevation are analysed. Four main regions of the drop and film are considered: the perturbed liquid film on the wall inside the crown, the unperturbed liquid film on the wall outside the crown, the upward jet forming a crown, and the free rim bounding this jet. The theory of Yarin & Weiss (1995) for the propagation of the kinematic discontinuity is generalized here for the case of arbitrary velocity vectors in the inner and outer liquid films on the wall. Next, the mass, momentum balance and Bernoulli equations at the base of the crown are considered in order to obtain the velocity and the thickness of the jet on the wall. Furthermore, the dynamic equations of motion of the crown are developed in the Lagrangian form. An analytical solution for the crown shape is obtained in the asymptotic case of such high impact velocities that the surface tension and the viscosity effects can be neglected in comparison to inertial effects. The edge of the crown is described by the motion of a rim, formed due to the surface tension.

  13. Subatomic movements of a domain wall in the Peierls potential.

    PubMed

    Novoselov, K S; Geim, A K; Dubonos, S V; Hill, E W; Grigorieva, I V

    2003-12-18

    The discrete nature of crystal lattices plays a role in virtually every material property. But it is only when the size of entities hosted by a crystal becomes comparable to the lattice period--as occurs for dislocations, vortices in superconductors and domain walls--that this discreteness is manifest explicitly. The associated phenomena are usually described in terms of a background Peierls 'atomic washboard' energy potential, which was first introduced for the case of dislocation motion in the 1940s. This concept has subsequently been invoked in many situations to describe certain features in the bulk behaviour of materials, but has to date eluded direct detection and experimental scrutiny at a microscopic level. Here we report observations of the motion of a single magnetic domain wall at the scale of the individual peaks and troughs of the atomic energy landscape. Our experiments reveal that domain walls can become trapped between crystalline planes, and that they propagate by distinct jumps that match the lattice periodicity. The jumps between valleys are found to involve unusual dynamics that shed light on the microscopic processes underlying domain-wall propagation. Such observations offer a means for probing experimentally the physics of topological defects in discrete lattices--a field rich in phenomena that have been subject to extensive theoretical study.

  14. Linear modeling of turbulent skin-friction reduction due to spanwise wall motion

    NASA Astrophysics Data System (ADS)

    Duque-Daza, Carlos; Baig, Mirza; Lockerby, Duncan; Chernyshenko, Sergei; Davies, Christopher; University of Warwick Team; Imperial College Team; Cardiff University Team

    2012-11-01

    We present a study on the effect of streamwise-travelling waves of spanwise wall velocity on the growth of near-wall turbulent streaks using a linearized formulation of the Navier-Stokes equations. The changes in streak amplification due to the travelling waves induced by the wall velocity are compared to published results of direct numerical simulation (DNS) predictions of the turbulent skin-friction reduction over a range of parameters; a clear correlation between these two sets of results is observed. Additional linearized simulations but at a much higher Reynolds numbers, more relevant to aerospace applications, produce results that show no marked differences to those obtained at low Reynolds number. It is also observed that a close correlation exists between DNS data of drag reduction and a very simple characteristic of the ``generalized'' Stokes layer generated by the streamwise-travelling waves. Carlos.Duque-Daza@warwick.ac.uk - School of Engineering, University of Warwick, Coventry CV4 7AL, UK caduqued@unal.edu.co - Department of Mechanical and Mechatronics Engineering, Universidad Nacional de Colombia.

  15. Self-motion perception: assessment by computer-generated animations

    NASA Technical Reports Server (NTRS)

    Parker, D. E.; Harm, D. L.; Sandoz, G. R.; Skinner, N. C.

    1998-01-01

    The goal of this research is more precise description of adaptation to sensory rearrangements, including microgravity, by development of improved procedures for assessing spatial orientation perception. Thirty-six subjects reported perceived self-motion following exposure to complex inertial-visual motion. Twelve subjects were assigned to each of 3 perceptual reporting procedures: (a) animation movie selection, (b) written report selection and (c) verbal report generation. The question addressed was: do reports produced by these procedures differ with respect to complexity and reliability? Following repeated (within-day and across-day) exposures to 4 different "motion profiles," subjects either (a) selected movies presented on a laptop computer, or (b) selected written descriptions from a booklet, or (c) generated self-motion verbal descriptions that corresponded most closely with their motion experience. One "complexity" and 2 reliability "scores" were calculated. Contrary to expectations, reliability and complexity scores were essentially equivalent for the animation movie selection and written report selection procedures. Verbal report generation subjects exhibited less complexity than did subjects in the other conditions and their reports were often ambiguous. The results suggest that, when selecting from carefully written descriptions and following appropriate training, people may be better able to describe their self-motion experience with words than is usually believed.

  16. An investigation of the effects of spanwise wall oscillation on the structure of a turbulent boundary layer

    NASA Astrophysics Data System (ADS)

    Trujillo, Steven Mathew

    Transition of a fluid boundary layer from a laminar to a turbulent regime is accompanied by a large increase in skin friction drag. The ability to manipulate the flow or its bounding geometry to reduce this drag effectively has been a long-sought goal in contemporary fluid mechanics. Recently, workers have demonstrated that continuous lateral oscillation of the flow's bounding surface is one means to this goal, producing significant drag reduction. The present study was performed to understand better the mechanism by which such a flow achieves drag reduction. An oscillating wall section was installed in a water channel facility, and the resulting flow was studied using laser Doppler velocimetry, hot-film anemometry, and visualization techniques. Traditional mean and fluctuating statistics were examined, as well as statistics computed from conditionally-sampled turbulent events. The dependence of these quantities on the phase of the oscillating surface's motion was also studied. Visualization-based studies were employed to provide insight into the structural changes brought on by the wall oscillation. The most dramatic changes effected by the wall motion were seen as reductions in frequency of bursts and sweeps, events which concentrate large production of Reynolds stress and which ultimately augment wall skin friction. These Reynolds-stress reductions were reflected in reductions in mean and fluctuating quantifies in the lower regions of the boundary layer. Other velocity measurements confirmed earlier workers' speculations that the secondary flow induced by the oscillating wall is comparable to Stokes' solution for an oscillating plate in a quiescent fluid. Other than this secondary flow, however, the boundary layer displayed essentially no dependence on the phase of the wall motion. A simple cost analysis showed that, in general, the energy cost required to implement this technique is greater than the savings it produces. The visualizations of the flow revealed a

  17. Notch-Boosted Domain Wall Propagation in Magnetic Nanowires

    NASA Astrophysics Data System (ADS)

    Wang, Xiang Rong; Yuan, Hauiyang

    Magnetic domain wall (DW) motion along a nanowire underpins many proposals of spintronic devices. High DW propagation velocity is obviously important because it determines the device speed. Thus it is interesting to search for effective control knobs of DW dynamics. We report a counter-intuitive finding that notches in an otherwise homogeneous magnetic nanowire can boost current-induced domain wall (DW) propagation. DW motion in notch-modulated wires can be classified into three phases: 1) A DW is pinned around a notch when the current density is below the depinning current density. 2) DW propagation velocity above the depinning current density is boosted by notches when non-adiabatic spin-transfer torque strength is smaller than the Gilbert damping constant. The boost can be many-fold. 3) DW propagation velocity is hindered when non-adiabatic spin-transfer torque strength is larger than the Gilbert damping constant. This work was supported by Hong Kong GRF Grants (Nos. 163011151 and 605413) and the Grant from NNSF of China (No. 11374249).

  18. Large exchange-dominated domain wall velocities in antiferromagnetically coupled nanowires

    NASA Astrophysics Data System (ADS)

    Kuteifan, Majd; Lubarda, M. V.; Fu, S.; Chang, R.; Escobar, M. A.; Mangin, S.; Fullerton, E. E.; Lomakin, V.

    2016-04-01

    Magnetic nanowires supporting field- and current-driven domain wall motion are envisioned for methods of information storage and processing. A major obstacle for their practical use is the domain-wall velocity, which is traditionally limited for low fields and currents due to the Walker breakdown occurring when the driving component reaches a critical threshold value. We show through numerical and analytical modeling that the Walker breakdown limit can be extended or completely eliminated in antiferromagnetically coupled magnetic nanowires. These coupled nanowires allow for large domain-wall velocities driven by field and/or current as compared to conventional nanowires.

  19. Low-dimensional representation of near-wall dynamics in shear flows, with implications to wall-models.

    PubMed

    Schmid, P J; Sayadi, T

    2017-03-13

    The dynamics of coherent structures near the wall of a turbulent boundary layer is investigated with the aim of a low-dimensional representation of its essential features. Based on a triple decomposition into mean, coherent and incoherent motion and a dynamic mode decomposition to recover statistical information about the incoherent part of the flow field, a driven linear system coupling first- and second-order moments of the coherent structures is derived and analysed. The transfer function for this system, evaluated for a wall-parallel plane, confirms a strong bias towards streamwise elongated structures, and is proposed as an 'impedance' boundary condition which replaces the bulk of the transport between the coherent velocity field and the coherent Reynolds stresses, thus acting as a wall model for large-eddy simulations (LES). It is interesting to note that the boundary condition is non-local in space and time. The extracted model is capable of reproducing the principal Reynolds stress components for the pretransitional, transitional and fully turbulent boundary layer.This article is part of the themed issue 'Toward the development of high-fidelity models of wall turbulence at large Reynolds number'. © 2017 The Author(s).

  20. Physical Sensing of Surface Properties by Microswimmers – Directing Bacterial Motion via Wall Slip

    PubMed Central

    Hu, Jinglei; Wysocki, Adam; Winkler, Roland G.; Gompper, Gerhard

    2015-01-01

    Bacteria such as Escherichia coli swim along circular trajectories adjacent to surfaces. Thereby, the orientation (clockwise, counterclockwise) and the curvature depend on the surface properties. We employ mesoscale hydrodynamic simulations of a mechano-elastic model of E. coli, with a spherocylindrical body propelled by a bundle of rotating helical flagella, to study quantitatively the curvature of the appearing circular trajectories. We demonstrate that the cell is sensitive to nanoscale changes in the surface slip length. The results are employed to propose a novel approach to directing bacterial motion on striped surfaces with different slip lengths, which implies a transformation of the circular motion into a snaking motion along the stripe boundaries. The feasibility of this approach is demonstrated by a simulation of active Brownian rods, which also reveals a dependence of directional motion on the stripe width. PMID:25993019

  1. Expermental Investigation of Supercavitating Motion of Bodies

    DTIC Science & Technology

    2001-02-01

    information is ensured by studying of the model motion kinematics and photo- cinematography of its flow pictures. 4-9 Synchronization of work of the...on the depth 0.5 m along the flume axis. Photo- cinematography of the flow pictures was realized through the glass windows in walls of the flume and

  2. Algorithm of chest wall keloid treatment

    PubMed Central

    Long, Xiao; Zhang, Mingzi; Wang, Yang; Zhao, Ru; Wang, Youbin; Wang, Xiaojun

    2016-01-01

    Abstract Keloids are common in the Asian population. Multiple or huge keloids can appear on the chest wall because of its tendency to develop acne, sebaceous cyst, etc. It is difficult to find an ideal treatment for keloids in this area due to the limit of local soft tissues and higher recurrence rate. This study aims at establishing an individualized protocol that could be easily applied according to the size and number of chest wall keloids. A total of 445 patients received various methods (4 protocols) of treatment in our department from September 2006 to September 2012 according to the size and number of their chest wall keloids. All of the patients received adjuvant radiotherapy in our hospital. Patient and Observer Scar Assessment Scale (POSAS) was used to assess the treatment effect by both doctors and patients. With mean follow-up time of 13 months (range: 6–18 months), 362 patients participated in the assessment of POSAS with doctors. Both the doctors and the patients themselves used POSAS to evaluate the treatment effect. The recurrence rate was 0.83%. There was an obvious significant difference (P < 0.001) between the before-surgery score and the after-surgery score from both doctors and patients, indicating that both doctors and patients were satisfied with the treatment effect. Our preliminary clinical result indicates that good clinical results could be achieved by choosing the proper method in this algorithm for Chinese patients with chest wall keloids. This algorithm could play a guiding role for surgeons when dealing with chest wall keloid treatment. PMID:27583896

  3. Nanoscale Origins of Ferroelastic Domain Wall Mobility in Ferroelectric Multilayers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Hsin-Hui; Hong, Zijian; Xin, Huolin L.

    Here we investigate the nanoscale origins of ferroelastic domain wall motion in ferroelectric multilayer thin films that lead to giant electromechanical responses. We present direct evidence for complex underpinning factors that result in ferroelastic domain wall mobility using a combination of atomic-level aberration corrected scanning transmission electron microscopy and phase-field simulations in model epitaxial (001) tetragonal (T) PbZr xTi 1-xO 3 (PZT)/rhombohedral (R) PbZr xTi 1-xO 3 (PZT) bilayer heterostructures. The local electric dipole distribution is imaged on an atomic scale for a ferroelastic domain wall that nucleates in the R-layer and cuts through the composition breaking the T/R interface.more » Our studies reveal a highly complex polarization rotation domain structure that is nearly on the knife-edge at the vicinity of this wall. Induced phases, namely tetragonal-like and rhombohedral-like monoclinic were observed close to the interface, and exotic domain arrangements, such as a half-four-fold closure structure, are observed. Phase field simulations show this is due to the minimization of the excessive elastic and electrostatic energies driven by the enormous strain gradient present at the location of the ferroelastic domain walls. Thus, in response to an applied stimulus, such as an electric field, any polarization reorientation must minimize the elastic and electrostatic discontinuities due to this strain gradient, which would induce a dramatic rearrangement of the domain structure. This insight into the origins of ferroelastic domain wall motion will allow researchers to better “craft” such multilayered ferroelectric systems with precisely tailored domain wall functionality and enhanced sensitivity, which can be exploited for the next generation of integrated piezoelectric technologies.« less

  4. Nanoscale Origins of Ferroelastic Domain Wall Mobility in Ferroelectric Multilayers

    DOE PAGES

    Huang, Hsin-Hui; Hong, Zijian; Xin, Huolin L.; ...

    2016-10-31

    Here we investigate the nanoscale origins of ferroelastic domain wall motion in ferroelectric multilayer thin films that lead to giant electromechanical responses. We present direct evidence for complex underpinning factors that result in ferroelastic domain wall mobility using a combination of atomic-level aberration corrected scanning transmission electron microscopy and phase-field simulations in model epitaxial (001) tetragonal (T) PbZr xTi 1-xO 3 (PZT)/rhombohedral (R) PbZr xTi 1-xO 3 (PZT) bilayer heterostructures. The local electric dipole distribution is imaged on an atomic scale for a ferroelastic domain wall that nucleates in the R-layer and cuts through the composition breaking the T/R interface.more » Our studies reveal a highly complex polarization rotation domain structure that is nearly on the knife-edge at the vicinity of this wall. Induced phases, namely tetragonal-like and rhombohedral-like monoclinic were observed close to the interface, and exotic domain arrangements, such as a half-four-fold closure structure, are observed. Phase field simulations show this is due to the minimization of the excessive elastic and electrostatic energies driven by the enormous strain gradient present at the location of the ferroelastic domain walls. Thus, in response to an applied stimulus, such as an electric field, any polarization reorientation must minimize the elastic and electrostatic discontinuities due to this strain gradient, which would induce a dramatic rearrangement of the domain structure. This insight into the origins of ferroelastic domain wall motion will allow researchers to better “craft” such multilayered ferroelectric systems with precisely tailored domain wall functionality and enhanced sensitivity, which can be exploited for the next generation of integrated piezoelectric technologies.« less

  5. Fractional Whirl Motion in Wave Journal Bearings

    NASA Technical Reports Server (NTRS)

    Dimofte, Florin; Hendricks, Robert C.

    1996-01-01

    Unloaded gas, plain journal bearings experience sub-synchronous whirl motion due to fluid film instabilities and wall contact usually occurs immediately after the onset of the whirl motion. An alternative is the wave journal bearing which significantly improves bearing stability. The predicted threshold where the sub-synchronous whirl motion starts was well confirmed by the experimental observation. In addition, both a two-wave and a three-wave journal bearing can operate free of sub-synchronous whirl motion over a large range in speeds. When the sub-synchronous whirl motion occurs, both the two-wave and three-wave bearing can run in a whirl orbit well within the bearing clearance. At large clearances and wave amplitudes a two-wave bearing, unliKe other bearings, can exhibit a sub-synchronous whirl movement at both low and high speeds, but can run extremely stable and without whirl at intermediate speeds. Moreover, in these cases, the whirl frequencies are close to a quarter of the synchronous speed. The three-wave bearing can exhibit sub-synchronous whirl motion only after a specific threshold when the speed increases and the whirl frequencies are close to half of the synchronous speed.

  6. Segmental front line dynamics of randomly pinned ferroelastic domain walls

    NASA Astrophysics Data System (ADS)

    Puchberger, S.; Soprunyuk, V.; Schranz, W.; Carpenter, M. A.

    2018-01-01

    Dynamic mechanical analysis (DMA) measurements as a function of temperature, frequency, and dynamic force amplitude are used to perform a detailed study of the domain wall motion in LaAlO3. In previous DMA measurements Harrison et al. [Phys. Rev. B 69, 144101 (2004), 10.1103/PhysRevB.69.144101] found evidence for dynamic phase transitions of ferroelastic domain walls in LaAlO3. In the present work we focus on the creep-to-relaxation region of domain wall motion using two complementary methods. We determine, in addition to dynamic susceptibility data, waiting time distributions of strain jerks during slowly increasing stress. These strain jerks, which result from self-similar avalanches close to the depinning threshold, follow a power-law behavior with an energy exponent ɛ =1.7 ±0.1 . Also, the distribution of waiting times between events follows a power law N (tw) ∝tw-(n +1 ) with an exponent n =0.9 , which transforms to a power law of susceptibility S (ω ) ∝ω-n . The present dynamic susceptibility data can be well fitted with a power law, with the same exponent (n =0.9 ) up to a characteristic frequency ω ≈ω* , where a crossover from stochastic DW motion to the pinned regime is well described using the scaling function of Fedorenko et al. [Phys. Rev. B 70, 224104 (2004), 10.1103/PhysRevB.70.224104].

  7. Measurement of the near-wall velocity profile for a nanofluid flow inside a microchannel

    NASA Astrophysics Data System (ADS)

    Kanjirakat, Anoop; Sadr, Reza

    2015-11-01

    Hydrodynamics and anomalous heat transfer enhancements have been reported in the past for colloidal suspensions of nano-sized particles dispersed in a fluid (nanofluids). However, such augmentations may manifest itself by study of fluid flow characteristics near in the wall region. Present experimental study reports near-wall velocity profile for nanofluids (silicon dioxide nanoparticles in water) measured inside a microchannel. An objective-based nano-Particle Image Velocimetry (nPIV) technique is used to measure fluid velocity within three visible depths, O(100nm), from the wall. The near-wall fluid velocity profile is estimated after implementing the required corrections for optical properties and effects caused by hindered Brownian motion, wall-particle interactions, and non-uniform exponential illumination on the measurement technique. The fluid velocities of nanofluids at each of the three visible depths are observed to be higher than that of the base fluid resulting in a higher shear rate in this region. The relative increase in shear rates for nanofluids is believed to be the result of the near-wall shear-induced particle migration along with the Brownian motion of the nanoparticles. This research is funded by NPRP grant # 08-574-2-239 from the Qatar National Research Fund (a member of Qatar Foundation).

  8. Use of the Animal Trauma Triage Score, RibScore, Modified RibScore and Other Clinical Factors for Prognostication in Canine Rib Fractures.

    PubMed

    McCarthy, Daniel; Bacek, Lenore; Kim, Kyoung; Miller, George; Gaillard, Philippe; Kuo, Kendon

    2018-06-11

     To characterize the clinical features among dogs sustaining rib fractures and to determine if age, type and severity of injury, entry blood lactate, trauma score and rib fracture score were associated with outcome.  A retrospective study was performed to include dogs that were presented with rib fractures. Risk factors evaluation included breed, age, body weight, diagnosis, presence of a flail chest, bandage use, puncture wound presence, rib fracture number, location of the fracture along the thoracic wall, hospital stay length, body weight, other fractures, pleural effusion, pulmonary contusions, pneumothorax and occurrence of an anaesthetic event. A retrospective calculation of an animal trauma triage (ATT) score, RibScore and Modified RibScore was assigned.  Forty-one medical records were collected. Motor vehicular trauma represented 56% of the rib fracture aetiology, 41% of patients sustained dog bites and one case was of an unknown aetiology. Significant correlations with risk factors were found only with the ATT score. All patients that died had an ATT score ≥ 5. The ATT score correlated positively with mortality ( p  < 0.05) with an ATT score ≥ 7 was 88% sensitive and 81% specific for predicting mortality. A 1-point increase in ATT score corresponded to 2.1 times decreased likelihood of survival. Mean hospital stay was 3 days longer for dog bite cases.  There was no increased mortality rate in canine patients that presented with the suspected risk factors. The only risk factor that predicted mortality was the ATT score. Schattauer GmbH Stuttgart.

  9. Gender differences in motion sickness history and susceptibility to optokinetic rotation-induced motion sickness.

    PubMed

    Park, A H; Hu, S

    1999-11-01

    The present study investigated gender differences in motion sickness history and susceptibility to optokinetic rotation-induced motion sickness. The study included two phases. In Phase 1, 485 subjects filled out a survey of previous incidence of motion sickness. Results indicated that women reported significantly greater incidence of feeling motion sickness than did men on buses, on trains, on planes, in cars, and on amusement rides before the age of 12 yr; and on buses, on trains, on planes, in boats, on ships, in cars, on amusement rides, and on swings between the ages of 12 and 25 yr. Women also reported significantly higher incidence of being actually sick than did men on buses before the age of 12 yr and on buses, on ships, and in cars between the ages of 12 and 25 yr. In Phase 2, each of the 47 subjects viewed an optokinetic rotating-drum for 16 min. Subjects' subjective symptoms of motion sickness (SSMS) were obtained during drum rotation. The results showed that there were no significant differences on SSMS scores between men and women. Although women reported greater incidence in motion sickness history, women did not differ from men in severity of symptoms of motion sickness while viewing a rotating optokinetic drum.

  10. Configural Scoring of Simulator Sickness, Cybersickness and Space Adaptation Syndrome: Similarities and Differences?

    NASA Technical Reports Server (NTRS)

    Kennedy, Robert S.; Drexler, Julie M.; Compton, Daniel E.; Stanney, Kay M.; Lanham, Susan; Harm, Deborah L.

    2001-01-01

    From a survey of ten U.S. Navy flight simulators a large number (N > 1,600 exposures) of self-reports of motion sickness symptomatology were obtained. Using these data, scoring algorithms were derived, which permit examination of groups of individuals that can be scored either for 1) their total sickness experience in a particular device; or, 2) according to three separable symptom clusters which emerged from a Factor Analysis. Scores from this total score are found to be proportional to other global motion sickness symptom checklist scores with which they correlate (r = 0.82). The factors that surfaced from the analysis include clusters of symptoms referable as nausea, oculomotor disturbances, and disorientation (N, 0, and D). The factor scores may have utility in differentiating the source of symptoms in different devices. The present chapter describes our experience with the use of both of these types of scores and illustrates their use with examples from flight simulators, space sickness and virtual environments.

  11. On the receptivity problem for Goertler vortices: Vortex motions induced by wall roughness

    NASA Technical Reports Server (NTRS)

    Denier, James P.; Hall, Philip; Seddougui, Sharon

    1990-01-01

    The receptivity problem for Goertler vortices induced by wall roughness is investigated. The roughness is modelled by small amplitude perturbations to the curved wall over which the flow takes place. The amplitude of these perturbations is taken to be sufficiently small for the induced Goertler vortices to be described by linear theory. The roughness is assumed to vary in the spanwise direction on the boundary layer lengthscale, while in the flow direction the corresponding variation is on the lengthscale over which the wall curvature varies. In fact the latter condition can be relaxed to allow for a faster streamwise roughness variation so long as the variation does not become as fast as that in the spanwise direction. The function which describes the roughness is assumed to be such that its spanwise and streamwise dependences can be separated; this enables progress by taking Fourier or Laplace transforms where appropriate. The cases of isolated and distributed roughness elements are investigated and the coupling coefficient which relates the amplitude of the forcing and the induced vortex amplitude is found asymptotically in the small wavelength limit. It is shown that this coefficient is exponentially small in the latter limit so that it is unlikely that this mode can be stimulated directly by wall roughness. The situation at 0(1) wavelengths is quite different and this is investigated numerically for different forcing functions. It is found that an isolated roughness element induces a vortex field which grows within a wedge at a finite distance downstream of the element. However, immediately downstream of the obstacle the disturbed flow produced by the element decays in amplitude. The receptivity problem at larger Goertler numbers appropriate to relatively large wall curvature is discussed in detail.

  12. Self-propulsion of a catalytically active particle near a planar wall: from reflection to sliding and hovering.

    PubMed

    Uspal, W E; Popescu, M N; Dietrich, S; Tasinkevych, M

    2015-01-21

    Micron-sized particles moving through a solution in response to self-generated chemical gradients serve as model systems for studying active matter. Their far-reaching potential applications will require the particles to sense and respond to their local environment in a robust manner. The self-generated hydrodynamic and chemical fields, which induce particle motion, probe and are modified by that very environment, including confining boundaries. Focusing on a catalytically active Janus particle as a paradigmatic example, we predict that near a hard planar wall such a particle exhibits several scenarios of motion: reflection from the wall, motion at a steady-state orientation and height above the wall, or motionless, steady "hovering." Concerning the steady states, the height and the orientation are determined both by the proportion of catalyst coverage and the interactions of the solutes with the different "faces" of the particle. Accordingly, we propose that a desired behavior can be selected by tuning these parameters via a judicious design of the particle surface chemistry.

  13. Registration Methods for IVUS: Transversal and Longitudinal Transducer Motion Compensation.

    PubMed

    Talou, Gonzalo D Maso; Blanco, Pablo J; Larrabide, Ignacio; Bezerra, Cristiano Guedes; Lemos, Pedro A; Feijoo, Raul A

    2017-04-01

    Intravascular ultrasound (IVUS) is a fundamental imaging technique for atherosclerotic plaque assessment, interventionist guidance, and, ultimately, as a tissue characterization tool. The studies acquired by this technique present the spatial description of the vessel during the cardiac cycle. However, the study frames are not properly sorted. As gating methods deal with the cardiac phase classification of the frames, the gated studies lack motion compensation between vessel and catheter. In this study, we develop registration strategies to arrange the vessel data into its rightful spatial sequence. Registration is performed by compensating longitudinal and transversal relative motion between vessel and catheter. Transversal motion is identified through maximum likelihood estimator optimization, while longitudinal motion is estimated by a neighborhood similarity estimator among the study frames. A strongly coupled implementation is proposed to compensate for both motion components at once. Loosely coupled implementations (DLT and DTL) decouple the registration process, resulting in more computationally efficient algorithms in detriment of the size of the set of candidate solutions. The DTL outperforms DLT and coupled implementations in terms of accuracy by a factor of 1.9 and 1.4, respectively. Sensitivity analysis shows that perivascular tissue must be considered to obtain the best registration outcome. Evidences suggest that the method is able to measure axial strain along the vessel wall. The proposed registration sorts the IVUS frames for spatial location, which is crucial for a correct interpretation of the vessel wall kinematics along the cardiac phases.

  14. Motion perception and driving: predicting performance through testing and shortening braking reaction times through training.

    PubMed

    Wilkins, Luke; Gray, Rob; Gaska, James; Winterbottom, Marc

    2013-12-30

    A driving simulator was used to examine the relationship between motion perception and driving performance. Although motion perception test scores have been shown to be related to driving safety, it is not clear which combination of tests are the best predictors and whether motion perception training can improve driving performance. In experiment 1, 60 younger drivers (22.4 ± 2.5 years) completed three motion perception tests (2-dimensional [2D] motion-defined letter [MDL] identification, 3D motion in depth sensitivity [MID], and dynamic visual acuity [DVA]) followed by two driving tests (emergency braking [EB] and hazard perception [HP]). In experiment 2, 20 drivers (21.6 ± 2.1 years) completed 6 weeks of motion perception training (using the MDL, MID, and DVA tests), while 20 control drivers (22.0 ± 2.7 years) completed an online driving safety course. The EB performance was measured before and after training. In experiment 1, MDL (r = 0.34) and MID (r = 0.46) significantly correlated with EB score. The change in DVA score as a function of target speed (i.e., "velocity susceptibility") was correlated most strongly with HP score (r = -0.61). In experiment 2, the motion perception training group had a significant decrease in brake reaction time on the EB test from pre- to posttreatment, while there was no significant change for the control group: t(38) = 2.24, P = 0.03. Tests of 3D motion perception are the best predictor of EB, while DVA velocity susceptibility is the best predictor of hazard perception. Motion perception training appears to result in faster braking responses.

  15. Domain wall energy landscapes in amorphous magnetic films with asymmetric arrays of holes

    NASA Astrophysics Data System (ADS)

    Alija, A.; Pérez-Junquera, A.; Rodríguez-Rodríguez, G.; Vélez, M.; Marconi, V. I.; Kolton, A. B.; Anguita, J. V.; Alameda, J. M.; Parrondo, J. M. R.; Martín, J. I.

    2009-02-01

    Arrays of asymmetric holes have been defined in amorphous Co-Si films by e-beam lithography in order to study domain wall motion across the array subject to the asymmetric pinning potential created by the holes. Experimental results on Kerr effect magnetooptical measurements and hysteresis loops are compared with micromagnetic simulations in films with arrays of triangular holes. These show that the potential asymmetry favours forward wall propagation for flat walls but, if the wall contains a kink, net backward wall propagation is preferred at low fields, in agreement with minor loop experiments. The difference between the fields needed for forward and backward flat wall propagation increases as the size of the triangular holes is reduced, becoming maximum for 1 µm triangles, which is the characteristic length scale set by domain wall width.

  16. Instrument Motion Metrics for Laparoscopic Skills Assessment in Virtual Reality and Augmented Reality.

    PubMed

    Fransson, Boel A; Chen, Chi-Ya; Noyes, Julie A; Ragle, Claude A

    2016-11-01

    To determine the construct and concurrent validity of instrument motion metrics for laparoscopic skills assessment in virtual reality and augmented reality simulators. Evaluation study. Veterinarian students (novice, n = 14) and veterinarians (experienced, n = 11) with no or variable laparoscopic experience. Participants' minimally invasive surgery (MIS) experience was determined by hospital records of MIS procedures performed in the Teaching Hospital. Basic laparoscopic skills were assessed by 5 tasks using a physical box trainer. Each participant completed 2 tasks for assessments in each type of simulator (virtual reality: bowel handling and cutting; augmented reality: object positioning and a pericardial window model). Motion metrics such as instrument path length, angle or drift, and economy of motion of each simulator were recorded. None of the motion metrics in a virtual reality simulator showed correlation with experience, or to the basic laparoscopic skills score. All metrics in augmented reality were significantly correlated with experience (time, instrument path, and economy of movement), except for the hand dominance metric. The basic laparoscopic skills score was correlated to all performance metrics in augmented reality. The augmented reality motion metrics differed between American College of Veterinary Surgeons diplomates and residents, whereas basic laparoscopic skills score and virtual reality metrics did not. Our results provide construct validity and concurrent validity for motion analysis metrics for an augmented reality system, whereas a virtual reality system was validated only for the time score. © Copyright 2016 by The American College of Veterinary Surgeons.

  17. Current-induced instability of domain walls in cylindrical nanowires

    NASA Astrophysics Data System (ADS)

    Wang, Weiwei; Zhang, Zhaoyang; Pepper, Ryan A.; Mu, Congpu; Zhou, Yan; Fangohr, Hans

    2018-01-01

    We study the current-driven domain wall (DW) motion in cylindrical nanowires using micromagnetic simulations by implementing the Landau-Lifshitz-Gilbert equation with nonlocal spin-transfer torque in a finite difference micromagnetic package. We find that in the presence of DW, Gaussian wave packets (spin waves) will be generated when the charge current is suddenly applied to the system. This effect is excluded when using the local spin-transfer torque. The existence of spin waves emission indicates that transverse domain walls can not move arbitrarily fast in cylindrical nanowires although they are free from the Walker limit. We establish an upper velocity limit for DW motion by analyzing the stability of Gaussian wave packets using the local spin-transfer torque. Micromagnetic simulations show that the stable region obtained by using nonlocal spin-transfer torque is smaller than that by using its local counterpart. This limitation is essential for multiple DWs since the instability of Gaussian wave packets will break the structure of multiple DWs.

  18. Three studies of motion sickness susceptibility.

    DOT National Transportation Integrated Search

    1976-01-01

    The incidence of motion sickness in a large (N = 3,618) college population was determined by means of a questionnaires. Significantly greater proportions of men than women had low susceptibility scores; significantly greater proportions of women had ...

  19. Building a Lego wall: Sequential action selection.

    PubMed

    Arnold, Amy; Wing, Alan M; Rotshtein, Pia

    2017-05-01

    The present study draws together two distinct lines of enquiry into the selection and control of sequential action: motor sequence production and action selection in everyday tasks. Participants were asked to build 2 different Lego walls. The walls were designed to have hierarchical structures with shared and dissociated colors and spatial components. Participants built 1 wall at a time, under low and high load cognitive states. Selection times for correctly completed trials were measured using 3-dimensional motion tracking. The paradigm enabled precise measurement of the timing of actions, while using real objects to create an end product. The experiment demonstrated that action selection was slowed at decision boundary points, relative to boundaries where no between-wall decision was required. Decision points also affected selection time prior to the actual selection window. Dual-task conditions increased selection errors. Errors mostly occurred at boundaries between chunks and especially when these required decisions. The data support hierarchical control of sequenced behavior. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  20. Assessing the effects of subject motion on T2 relaxation under spin tagging (TRUST) cerebral oxygenation measurements using volume navigators.

    PubMed

    Stout, Jeffrey N; Tisdall, M Dylan; McDaniel, Patrick; Gagoski, Borjan; Bolar, Divya S; Grant, Patricia Ellen; Adalsteinsson, Elfar

    2017-12-01

    Subject motion may cause errors in estimates of blood T 2 when using the T 2 -relaxation under spin tagging (TRUST) technique on noncompliant subjects like neonates. By incorporating 3D volume navigators (vNavs) into the TRUST pulse sequence, independent measurements of motion during scanning permit evaluation of these errors. The effects of integrated vNavs on TRUST-based T 2 estimates were evaluated using simulations and in vivo subject data. Two subjects were scanned with the TRUST+vNav sequence during prescribed movements. Mean motion scores were derived from vNavs and TRUST images, along with a metric of exponential fit quality. Regression analysis was performed between T 2 estimates and mean motion scores. Also, motion scores were determined from independent neonatal scans. vNavs negligibly affected venous blood T 2 estimates and better detected subject motion than fit quality metrics. Regression analysis showed that T 2 is biased upward by 4.1 ms per 1 mm of mean motion score. During neonatal scans, mean motion scores of 0.6 to 2.0 mm were detected. Motion during TRUST causes an overestimate of T 2 , which suggests a cautious approach when comparing TRUST-based cerebral oxygenation measurements of noncompliant subjects. Magn Reson Med 78:2283-2289, 2017. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  1. SU-E-T-571: Prostate IMRT QA: Prediction of the Range of Rectal NTCP Using a 2D Field Approach Based on Variations of the Rectal Wall Motion and Thickness.

    PubMed

    Grigorov, G; Chow, J; Foster, K

    2012-06-01

    The aims of this study is to (1) introduce a 2D field of possible rectal normal tissue complication probability (NTCP) in prostate intensity modulated radiotherapy (IMRT) plan, so that based on a given prescribed dose the rectal NTCP is merely a function of the rectal wall thickness and rectal motion; and (2) separate the 2D field of rectal NTCP into area of low risk and area of high risk for rectal toxicity < Grade II, based on the threshold rectal NTCP. The 2D field of NTCP model was developed using ten randomly selected prostate IMRT plans. The clinical rectal geometry was initially represented by the cylindrical contour in the treatment planning system. Different combinations of rectal motions, rectal wall thicknesses, planning target volume margins and prescribed doses were used to determine the NTCP in prostate IMRT plans. It was found that the functions bordering the 2D field for the given AP, LR and SI direction can be described as exponential, quadratic and linear equations, respectively. A ratio of the area of 2D field containing data of the low risk NTCP to the entire area of the field was introduced and calculated. Although our method is based on the Kutcher's dose response model and published tissue parameters, other mathematical models can be used in our approach. The 2D field of rectal NTCP is useful to estimate the rectal NTCP range in the prostate pre-treatment and treatment QA. Our method can determine the patient's threshold immobilization for a given rectal wall thickness so that prescribed dose can be delivered to the prostate to avoid rectal complication. Our method is also applicable to multi-phase prostate IMRT, and can be adapted to any treatment planning systems. © 2012 American Association of Physicists in Medicine.

  2. Influence of Brownian Motion on Blood Platelet Flow Behavior and Adhesive Dynamics near a Planar Wall

    PubMed Central

    Mody, Nipa A.; King, Michael R.

    2008-01-01

    We used the Platelet Adhesive Dynamics computational method to study the influence of Brownian motion of a platelet on its flow characteristics near a surface in the creeping flow regime. Two important characterizations were done in this regard: (1) quantification of the platelet’s ability to contact the surface by virtue of the Brownian forces and torques acting on it, and (2) determination of the relative importance of Brownian motion in promoting surface encounters in the presence of shear flow. We determined the Peclet number for a platelet undergoing Brownian motion in shear flow, which could be expressed as a simple linear function of height of the platelet centroid, H from the surface Pe (platelet) = γ. · (1.56H + 0.66) for H > 0.3 μm. Our results demonstrate that at timescales relevant to shear flow in blood, Brownian motion plays an insignificant role in influencing platelet motion or creating further opportunities for platelet-surface contact. The platelet Peclet number at shear rates > 100 s-1 is large enough (> 200) to neglect platelet Brownian motion in computational modeling of flow in arteries and arterioles for most practical purposes even at very close distances from the surface. We also conducted adhesive dynamics simulations to determine the effects of platelet Brownian motion on GPIbα-vWF-A1 single-bond dissociation dynamics. Brownian motion was found to have little effect on bond lifetime and caused minimal bond stressing as bond rupture forces were calculated to be less than 0.005 pN. We conclude from our results that for the case of platelet-shaped cells, Brownian motion is not expected to play an important role in influencing flow characteristics, platelet-surface contact frequency and dissociative binding phenomena under flow at physiological shear rates (> 50 s-1). PMID:17417890

  3. Influence of Brownian motion on blood platelet flow behavior and adhesive dynamics near a planar wall.

    PubMed

    Mody, Nipa A; King, Michael R

    2007-05-22

    We used the platelet adhesive dynamics computational method to study the influence of Brownian motion of a platelet on its flow characteristics near a surface in the creeping flow regime. Two important characterizations were done in this regard: (1) quantification of the platelet's ability to contact the surface by virtue of the Brownian forces and torques acting on it, and (2) determination of the relative importance of Brownian motion in promoting surface encounters in the presence of shear flow. We determined the Peclet number for a platelet undergoing Brownian motion in shear flow, which could be expressed as a simple linear function of height of the platelet centroid, H from the surface Pe (platelet) = . (1.56H + 0.66) for H > 0.3 microm. Our results demonstrate that at timescales relevant to shear flow in blood Brownian motion plays an insignificant role in influencing platelet motion or creating further opportunities for platelet-surface contact. The platelet Peclet number at shear rates >100 s-1 is large enough (>200) to neglect platelet Brownian motion in computational modeling of flow in arteries and arterioles for most practical purposes even at very close distances from the surface. We also conducted adhesive dynamics simulations to determine the effects of platelet Brownian motion on GPIbalpha-vWF-A1 single-bond dissociation dynamics. Brownian motion was found to have little effect on bond lifetime and caused minimal bond stressing as bond rupture forces were calculated to be less than 0.005 pN. We conclude from our results that, for the case of platelet-shaped cells, Brownian motion is not expected to play an important role in influencing flow characteristics, platelet-surface contact frequency, and dissociative binding phenomena under flow at physiological shear rates (>50 s(-1)).

  4. Coupling between Current and Dynamic Magnetization : from Domain Walls to Spin Waves

    NASA Astrophysics Data System (ADS)

    Lucassen, M. E.

    2012-05-01

    So far, we have derived some general expressions for domain-wall motion and the spin motive force. We have seen that the β parameter plays a large role in both subjects. In all chapters of this thesis, there is an emphasis on the determination of this parameter. We also know how to incorporate thermal fluctuations for rigid domain walls, as shown above. In Chapter 2, we study a different kind of fluctuations: shot noise. This noise is caused by the fact that an electric current consists of electrons, and therefore has fluctuations. In the process, we also compute transmission and reflection coefficients for a rigid domain wall, and from them the linear momentum transfer. More work on fluctuations is done in Chapter 3. Here, we consider a (extrinsically pinned) rigid domain wall under the influence of thermal fluctuations that induces a current via spin motive force. We compute how the resulting noise in the current is related to the β parameter. In Chapter 4 we look into in more detail into the spin motive forces from field driven domain walls. Using micro magnetic simulations, we compute the spin motive force due to vortex domain walls explicitly. As mentioned before, this gives qualitatively different results than for a rigid domain wall. The final subject in Chapter 5 is the application of the general expression for spin motive forces to magnons. Although this might seem to be unrelated to domain-wall motion, this calculation allows us to relate the β parameter to macroscopic transport coefficients. This work was supported by Stichting voor Fundamenteel Onderzoek der Materie (FOM), the Netherlands Organization for Scientific Research (NWO), and by the European Research Council (ERC) under the Seventh Framework Program (FP7).

  5. Fast Numerical Simulation of Focused Ultrasound Treatments During Respiratory Motion With Discontinuous Motion Boundaries.

    PubMed

    Schwenke, Michael; Georgii, Joachim; Preusser, Tobias

    2017-07-01

    Focused ultrasound (FUS) is rapidly gaining clinical acceptance for several target tissues in the human body. Yet, treating liver targets is not clinically applied due to a high complexity of the procedure (noninvasiveness, target motion, complex anatomy, blood cooling effects, shielding by ribs, and limited image-based monitoring). To reduce the complexity, numerical FUS simulations can be utilized for both treatment planning and execution. These use-cases demand highly accurate and computationally efficient simulations. We propose a numerical method for the simulation of abdominal FUS treatments during respiratory motion of the organs and target. Especially, a novel approach is proposed to simulate the heating during motion by solving Pennes' bioheat equation in a computational reference space, i.e., the equation is mathematically transformed to the reference. The approach allows for motion discontinuities, e.g., the sliding of the liver along the abdominal wall. Implementing the solver completely on the graphics processing unit and combining it with an atlas-based ultrasound simulation approach yields a simulation performance faster than real time (less than 50-s computing time for 100 s of treatment time) on a modern off-the-shelf laptop. The simulation method is incorporated into a treatment planning demonstration application that allows to simulate real patient cases including respiratory motion. The high performance of the presented simulation method opens the door to clinical applications. The methods bear the potential to enable the application of FUS for moving organs.

  6. Collective motion of squirmers in a quasi-2D geometry

    NASA Astrophysics Data System (ADS)

    Zöttl, Andreas; Stark, Holger

    2013-03-01

    Microorganisms like bacteria, algae or spermatozoa typically move in an aqueous environment where they interact via hydrodynamic flow fields. Recent experiments studied the collective motion of dense suspensions of bacteria where swarming and large-scale turbulence emerged. Moreover, spherical artificial microswimmers, so-called squirmers, have been constructed and studied in a quasi-2D geometry. Here we present a numerical study of the collective dynamics of squirmers confined in quasi-2D between two parallel walls. Because of their spherical shape the reorientation of squirmers is solely due to noise and hydrodynamic interactions via induced flow fields. This is in contrast to elongated swimmers like bacteria which locally align due to steric interactions. We study the collective motion of pushers, pullers and potential swimmers at different densities. At small densities the squirmers are oriented parallel to the walls and pairwise collisions determine the reorientation rate. In dense suspensions rotational diffusion is greatly enhanced and pushers, in particular, tend to orient perpendicular to the walls. This effects the dynamics of the emerging clusters. In very dense suspensions we observe active jamming and long-lived crystalline structures.

  7. High-speed schlieren videography of vortex-ring impact on a wall

    NASA Astrophysics Data System (ADS)

    Kissner, Benjamin; Hargather, Michael; Settles, Gary

    2011-11-01

    Ring vortices of approximately 20 cm diameter are generated through the use of an Airzooka toy. To make the vortex visible, it is seeded with difluoroethane gas, producing a refractive-index difference with the air. A 1-meter-diameter, single-mirror, double-pass schlieren system is used to visualize the ring-vortex motion, and also to provide the wall with which the vortex collides. High-speed imaging is provided by a Photron SA-1 digital video camera. The Airzooka is fired toward the mirror almost along the optical axis of the schlieren system, so that the view of the vortex-mirror collision is normal to the path of vortex motion. Vortex-wall interactions similar to those first observed by Walker et al. (JFM 181, 1987) are recorded at high speed. The presentation will consist of a screening and discussion of these video results.

  8. Low field domain wall dynamics in artificial spin-ice basis structure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kwon, J.; School of Electrical and Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798; Goolaup, S.

    2015-10-28

    Artificial magnetic spin-ice nanostructures provide an ideal platform for the observation of magnetic monopoles. The formation of a magnetic monopole is governed by the motion of a magnetic charge carrier via the propagation of domain walls (DWs) in a lattice. To date, most experiments have been on the static visualization of DW propagation in the lattice. In this paper, we report on the low field dynamics of DW in a unit spin-ice structure measured by magnetoresistance changes. Our results show that reversible DW propagation can be initiated within the spin-ice basis. The initial magnetization configuration of the unit structure stronglymore » influences the direction of DW motion in the branches. Single or multiple domain wall nucleation can be induced in the respective branches of the unit spin ice by the direction of the applied field.« less

  9. Coordination Between Ribs Motion and Thoracoabdominal Volumes in Swimmers During Respiratory Maneuvers

    PubMed Central

    Sarro, Karine J.; Silvatti, Amanda P.; Barros, Ricardo M. L.

    2008-01-01

    This work aimed to verify if swimmers present better chest wall coordination during breathing than healthy non-athletes analyzing the correlation between ribs motion and the variation of thoracoabdominal volumes. The results of two up-to-date methods based on videogrammetry were correlated in this study. The first one measured the volumes of 4 separate compartments of the chest wall (superior thorax, inferior thorax, superior abdomen and inferior abdomen) as a function of time. The second calculated the rotation angle of the 2nd to the 10th ribs around the quasi-transversal axis also in function of time. The chest wall was represented by 53 markers, attached to the ribs, vertebrae, thorax and abdomen of 15 male swimmers and of 15 non- athletes. A kinematical analysis system equipped with 6 digital video cameras (60Hz) was used to obtain the 3D coordinates of the markers. Correlating the curves of ribs rotation angles with the curves of the separate volumes, swimmers presented higher values than non-athletes when the superior and inferior abdomen were considered and the highest correlation values were found in swimmers for the inferior thorax. These results suggest a better coordination between ribs motion and thoracoabdominal volumes in swimmers, indicating the prevalent and coordinated action of the diaphragm and abdominal muscles to inflate and deflate the chest wall. The results further suggest that swimming practice leads to the formation of an optimized breathing pattern and can partially explain the higher lung volumes found in these athletes reported in literature. Key pointsThe study revealed that swimmers present higher correlation between the ribs motion and the variation of abdominal volumes than non-swimmers, suggesting that swimming practice might lead to the formation of an optimized breathing pattern, increasing the coordination between the thoracoabdominal volumes and the ribs motion.No previous work was found in the literature reporting this

  10. Myocardial imaging with 99mTc-Tetrofosmin: Influence of post-stress acquisition time, regional radiotracer uptake, and wall motion abnormalities on the clinical result.

    PubMed

    Giorgetti, Assuero; Kusch, Annette; Casagranda, Mirta; Tagliavia, Irene D'Aragona; Marzullo, Paolo

    2010-04-01

    We previously demonstrated that early (15', T1) post-stress myocardial imaging with Tetrofosmin could be more accurate than standard acquisitions (45', T2) in identifying coronary artery disease. To clarify this phenomenon, 120 subjects (age 61 +/- 10 years) with both T1 and T2 scans were divided into Group 1 (53/120 pts) with more ischemia at T1 vs T2 imaging (T1-T2SDS > or = 3); Group 2 (67/120 pts) with similar results (T1-T2SDS < or = 2). Myocardial areas were categorized as control nonischemic, ischemic, and scarred on the basis of perfusion/contraction properties and coronary anatomy. In each area, regional myocardial count statistic and semiquantitative wall motion/thickening values were obtained. Analysis of T1 and T2 post-stress myocardial counts demonstrated a significant Tetrofosmin wash-out rate that was higher in Group 1 control nonischemic regions (15 +/- 8% vs 13.6 +/- 9.6%, P < .02), significantly lower in Group 1 ischemic regions (7 +/- 10% vs 12.2 +/- 9.5%, P < .0001), and comparable between scarred areas of the two groups (P = NS). Delta post-stress wall thickening (T1-T2) was lower in Group 1 ischemic regions (-4.5 +/- 9.15% vs -1.90 +/- 7.0%, P < .001) and comparable in both control nonischemic and scarred areas of the two groups (P = NS). The clinical result of Tetrofosmin gated-SPECT can be influenced by the post-stress acquisition time because of ischemic-induced regional wall thickening abnormalities and the existence of a differential radiotracer myocardial wash-out.

  11. Electrical acustimulation relieves vection-induced motion sickness

    NASA Technical Reports Server (NTRS)

    Hu, S.; Stern, R. M.; Koch, K. L.

    1992-01-01

    The aim of this study was to examine the effects of electrical acustimulation on gastric myoelectric activity and severity of symptoms of motion sickness. In experiment 1, 16 Chinese subjects received electrical acustimulation in one of two sessions. In experiment 2, 45 white and black American subjects were randomly divided into three groups: acustimulation, sham acustimulation, and control. Each subject sat in an optokinetic drum for 15 minutes baseline and 15 minutes of drum rotation. Subjects' electrogastrograms and subjective symptoms of motion sickness were obtained. In experiment 1, the mean symptom score and tachyarrhythmia during acustimulation sessions were significantly lower than during no-acustimulation sessions. In experiment 2, the mean symptom score of the acustimulation group was significantly lower than that of the sham-stimulation group and the control group; tachyarrhythmia in the acustimulation group was significantly less than that of the control group but not the sham-stimulation group. In conclusion, electrical acustimulation reduces the severity of symptoms of motion sickness and appears to decrease gastric tachyarrhythmia.

  12. OSCILLATING LIGHT WALL ABOVE A SUNSPOT LIGHT BRIDGE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Shuhong; Zhang, Jun; Jiang, Fayu

    With the high tempo-spatial Interface Region Imaging Spectrograph 1330 Å images, we find that many bright structures are rooted in the light bridge of NOAA 12192, forming a light wall. The light wall is brighter than the surrounding areas, and the wall top is much brighter than the wall body. The New Vacuum Solar Telescope Hα and the Solar Dynamics Observatory 171 and 131 Å images are also used to study the light-wall properties. In 1330, 171, and 131 Å, the top of the wall has a higher emission, while in the Hα line, the wall-top emission is very low.more » The wall body corresponds to bright areas in 1330 Å and dark areas in the other lines. The top of the light wall moves upward and downward successively, performing oscillations in height. The deprojected mean height, amplitude, oscillation velocity, and the dominant period are determined to be 3.6 Mm, 0.9 Mm, 15.4 km s{sup −1}, and 3.9 minutes, respectively. We interpret the oscillations of the light wall as the leakage of p-modes from below the photosphere. The constant brightness enhancement of the wall top implies the existence of some kind of atmospheric heating, e.g., via the persistent small-scale reconnection or the magneto-acoustic waves. In another series of 1330 Å images, we find that the wall top in the upward motion phase is significantly brighter than in the downward phase. This kind of oscillation may be powered by the energy released due to intermittent impulsive magnetic reconnection.« less

  13. Small-scale deflagration cylinder test with velocimetry wall-motion diagnostics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hooks, Daniel E; Hill, Larry G; Pierce, Timothy H

    Predicting the likelihood and effects of outcomes resultant from thermal initiation of explosives remains a significant challenge. For certain explosive formulations, the general outcome can be broadly predicted given knowledge of certain conditions. However, there remain unexplained violent events, and increased statistical understanding of outcomes as a function of many variables, or 'violence categorization,' is needed. Additionally, the development of an equation of state equivalent for deflagration would be very useful in predicting possible detailed event consequences using traditional hydrodynamic detonation moders. For violence categorization, it is desirable that testing be efficient, such that it is possible to statistically definemore » outcomes reliant on the processes of initiation of deflagration, steady state deflagration, and deflagration to detonation transitions. If the test simultaneously acquires information to inform models of violent deflagration events, overall predictive capabilities for event likelihood and consequence might improve remarkably. In this paper we describe an economical scaled deflagration cylinder test. The cyclotetramethylene tetranitramine (HMX) based explosive formu1lation PBX 9501 was tested using different temperature profiles in a thick-walled copper cylindrical confiner. This test is a scaled version of a recently demonstrated deflagration cylinder test, and is similar to several other thermal explosion tests. The primary difference is the passive velocimetry diagnostic, which enables measurement of confinement vessel wall velocities at failure, regardless of the timing and location of ignition.« less

  14. Site-specific volumetric analysis of lung tumour motion

    NASA Astrophysics Data System (ADS)

    Pepin, Eric W.; Wu, Huanmei; Sandison, George A.; Langer, Mark; Shirato, Hiroki

    2010-06-01

    The treatment of lung cancer with radiation therapy is hindered by respiratory motion. Real-time adjustments to compensate for this motion are hampered by mechanical system latencies and imaging-rate restrictions. To better understand tumour motion behaviour for adaptive image-guided radiation therapy of lung cancer, the volume of a tumour's motion space was investigated. Motion data were collected by tracking an implanted fiducial using fluoroscopy at 30 Hz during treatment sessions. A total of 637 treatment fractions from 31 tumours were used in this study. For each fraction, data points collected from three consecutive breathing cycles were used to identify instantaneous tumour location. A convex hull was created over these data points, defining the tumour motion envelope. The study sought a correlation between the tumour location in the lung and the convex hull's volume and shape. It was found that tumours located in the upper apex had smaller motion envelopes (<50 mm3), whereas tumours located near the chest wall or diaphragm had larger envelopes (>70 mm3). Tumours attached to fixed anatomical structures had small motion spaces. Three general shapes described the tumour motion envelopes: 50% of motion envelopes enclosed largely 1D oscillation, 38% enclosed an ellipsoid path, 6% enclosed an arced path and 6% were of hybrid shape. This location-space correlation suggests it may be useful in developing a predictive model, but more work needs to be done to verify it.

  15. Effect of metallic walls on dynamos generated by laminar boundary-driven flow in a spherical domain.

    PubMed

    Guervilly, Céline; Wood, Toby S; Brummell, Nicholas H

    2013-11-01

    We present a numerical study of dynamo action in a conducting fluid encased in a metallic spherical shell. Motions in the fluid are driven by differential rotation of the outer metallic shell, which we refer to as "the wall." The two hemispheres of the wall are held in counter-rotation, producing a steady, axisymmetric interior flow consisting of differential rotation and a two-cell meridional circulation with radial inflow in the equatorial plane. From previous studies, this type of flow is known to maintain a stationary equatorial dipole by dynamo action if the magnetic Reynolds number is larger than about 300 and if the outer boundary is electrically insulating. We vary independently the thickness, electrical conductivity, and magnetic permeability of the wall to determine their effect on the dynamo action. The main results are the following: (a) Increasing the conductivity of the wall hinders the dynamo by allowing eddy currents within the wall, which are induced by the relative motion of the equatorial dipole field and the wall. This processes can be viewed as a skin effect or, equivalently, as the tearing apart of the dipole by the differential rotation of the wall, to which the field lines are anchored by high conductivity. (b) Increasing the magnetic permeability of the wall favors dynamo action by constraining the magnetic field lines in the fluid to be normal to the wall, thereby decoupling the fluid from any induction in the wall. (c) Decreasing the wall thickness limits the amplitude of the eddy currents, and is therefore favorable for dynamo action, provided that the wall is thinner than the skin depth. We explicitly demonstrate these effects of the wall properties on the dynamo field by deriving an effective boundary condition in the limit of vanishing wall thickness.

  16. Assessing Arthroscopic Skills Using Wireless Elbow-Worn Motion Sensors.

    PubMed

    Kirby, Georgina S J; Guyver, Paul; Strickland, Louise; Alvand, Abtin; Yang, Guang-Zhong; Hargrove, Caroline; Lo, Benny P L; Rees, Jonathan L

    2015-07-01

    Assessment of surgical skill is a critical component of surgical training. Approaches to assessment remain predominantly subjective, although more objective measures such as Global Rating Scales are in use. This study aimed to validate the use of elbow-worn, wireless, miniaturized motion sensors to assess the technical skill of trainees performing arthroscopic procedures in a simulated environment. Thirty participants were divided into three groups on the basis of their surgical experience: novices (n = 15), intermediates (n = 10), and experts (n = 5). All participants performed three standardized tasks on an arthroscopic virtual reality simulator while wearing wireless wrist and elbow motion sensors. Video output was recorded and a validated Global Rating Scale was used to assess performance; dexterity metrics were recorded from the simulator. Finally, live motion data were recorded via Bluetooth from the wireless wrist and elbow motion sensors and custom algorithms produced an arthroscopic performance score. Construct validity was demonstrated for all tasks, with Global Rating Scale scores and virtual reality output metrics showing significant differences between novices, intermediates, and experts (p < 0.001). The correlation of the virtual reality path length to the number of hand movements calculated from the wireless sensors was very high (p < 0.001). A comparison of the arthroscopic performance score levels with virtual reality output metrics also showed highly significant differences (p < 0.01). Comparisons of the arthroscopic performance score levels with the Global Rating Scale scores showed strong and highly significant correlations (p < 0.001) for both sensor locations, but those of the elbow-worn sensors were stronger and more significant (p < 0.001) than those of the wrist-worn sensors. A new wireless assessment of surgical performance system for objective assessment of surgical skills has proven valid for assessing arthroscopic skills. The elbow

  17. Orbital motions of bubbles in an acoustic field

    NASA Astrophysics Data System (ADS)

    Shirota, Minori; Yamashita, Ko; Inamura, Takao

    2012-09-01

    This experimental study aims to clarify the mechanism of orbital motion of two oscillating bubbles in an acoustic field. Trajectory of the orbital motion on the wall of a spherical levitator was observed using a high-speed video camera. Because of a good repeatability in volume oscillation of bubbles, we were also able to observe the radial motion driven at 24 kHz by stroboscopic like imaging technique. The orbital motions of bubbles raging from 0.13 to 0.18 mm were examined with different forcing amplitude and in different viscous oils. As a result, we found that pairs of bubbles revolve along an elliptic orbit around the center of mass of the bubbles. We also found that the two bubbles perform anti-phase radial oscillation. Although this radial oscillation should result in a repulsive secondary Bjerknes force, the bubbles kept a constant separate distance of about 1 mm, which indicates the existence of centripetal primary Bjerknes force.

  18. Motion perception tasks as potential correlates to driving difficulty in the elderly

    NASA Astrophysics Data System (ADS)

    Raghuram, A.; Lakshminarayanan, V.

    2006-09-01

    Changes in the demographics indicates that the population older than 65 is on the rise because of the aging of the ‘baby boom’ generation. This aging trend and driving related accident statistics reveal the need for procedures and tests that would assess the driving ability of older adults and predict whether they would be safe or unsafe drivers. Literature shows that an attention based test called the useful field of view (UFOV) was a significant predictor of accident rates compared to any other visual function tests. The present study evaluates a qualitative trend on using motion perception tasks as a potential visual perceptual correlates in screening elderly drivers who might have difficulty in driving. Data was collected from 15 older subjects with a mean age of 71. Motion perception tasks included—speed discrimination with radial and lamellar motion, time to collision using prediction motion and estimating direction of heading. A motion index score was calculated which was indicative of performance on all of the above-mentioned motion tasks. Scores on visual attention was assessed using UFOV. A driving habit questionnaire was also administered for a self report on the driving difficulties and accident rates. A qualitative trend based on frequency distributions show that thresholds on the motion perception tasks are successful in identifying subjects who reported to have had difficulty in certain aspects of driving and had accidents. Correlation between UFOV and motion index scores was not significant indicating that probably different aspects of visual information processing that are crucial to driving behaviour are being tapped by these two paradigms. UFOV and motion perception tasks together can be a better predictor for identifying at risk or safe drivers than just using either one of them.

  19. Prevalence, Predictors, and Prevention of Motion Sickness in Zero-G Parabolic Flights.

    PubMed

    Golding, John F; Paillard, Aurore C; Normand, Hervé; Besnard, Stéphane; Denise, Pierre

    2017-01-01

    Zero-G parabolic flight reproduces the weightlessness of space for short periods. However, motion sickness may affect some fliers. The aim was to assess the extent of this problem and to find possible predictors and modifying factors. Airbus zero-G flights consist of 31 parabolas performed in blocks. Each parabola consisted of 20 s of 0 g sandwiched by 20 s of hypergravity of 1.5-1.8 g. The survey covered N = 246 person-flights (193 men, 53 women), ages (M ± SD) 36.0 ± 11.3 yr. An anonymous questionnaire included motion sickness rating (1 = OK to 6 = vomiting), Motion Sickness Susceptibility Questionnaire (MSSQ), antimotion sickness medication, prior zero-G experience, anxiety level, and other characteristics. Participants had lower MSSQ percentile scores (27.4 ± 28.0) than the population norm of 50. Motion sickness was experienced by 33% and 12% vomited. Less motion sickness was predicted by older age, greater prior zero-G flight experience, medication with scopolamine, lower MSSQ scores, but not gender or anxiety. Sickness ratings in fliers pretreated with scopolamine (1.81 ± 1.58) were lower than for nonmedicated fliers (2.93 ± 2.16), and incidence of vomiting in fliers using scopolamine treatment was reduced by half to a third. Possible confounding factors including age, sex, flight experience, and MSSQ could not account for this. Motion sickness affected one-third of zero-G fliers despite being intrinsically less motion sickness susceptible compared to the general population. Susceptible individuals probably try to avoid such a provocative environment. Risk factors for motion sickness included younger age and higher MSSQ scores. Protective factors included prior zero-G flight experience (habituation) and antimotion sickness medication.Golding JF, Paillard AC, Normand H, Besnard S, Denise P. Prevalence, predictors, and prevention of motion sickness in zero-G parabolic flights. Aerosp Med Hum Perform. 2017; 88(1):3-9.

  20. SU-E-T-639: Proton Dose Calculation for Irregular Motion Using a Sliding Interface

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Phillips, J; Gueorguiev, G; Grassberger, C

    2015-06-15

    Purpose: While many techniques exist to evaluate dose to regularly moving lung targets, there are few available to calculate dose at tumor positions not present in the 4DCT. We have previously developed a method that extrapolates an existing dose to a new tumor location. In this abstract, we present a novel technique that accounts for relative anatomical shifts at the chest wall interface. We also utilize this procedure to simulate breathing motion functions on a cohort of eleven patients. Amplitudes exceeding the original range of motion were used to evaluate coverage using several aperture and smearing beam settings. Methods: Themore » water-equivalent depth (WED) technique requires an initial dose and CT image at the corresponding tumor position. Each dose volume was converted from its Cartesian geometry into a beam-specific radiological depth space. The sliding chest wall interface was determined by converting the lung contour into this same space. Any dose proximal to the initial boundary of the warped lung contour was held fixed, while the remaining distal dose was moved in the direction of motion along the interface. Results: V95 coverage was computed for each patient using the updated algorithm. Incorporation of the sliding motion yielded large dose differences, with gamma pass rates as low as 69.7% (3mm, 3%) and V95 coverage differences up to 2.0%. Clinical coverage was maintained for most patients with 5 mm excess simulated breathing motion, and up to 10 mm of excess motion was tolerated for a subset of patients and beam settings. Conclusion: We have established a method to determine the maximum allowable excess breathing motion for a given plan on a patient-by-patient basis. By integrating a sliding chest wall interface into our dose calculation technique, we have analyzed the robustness of breathing patterns that differ during treatment from at the time of 4DCT acquisition.« less

  1. Universal Pinning Energy Barrier for Driven Domain Walls in Thin Ferromagnetic Films

    NASA Astrophysics Data System (ADS)

    Jeudy, V.; Mougin, A.; Bustingorry, S.; Savero Torres, W.; Gorchon, J.; Kolton, A. B.; Lemaître, A.; Jamet, J.-P.

    2016-07-01

    We report a comparative study of magnetic field driven domain wall motion in thin films made of different magnetic materials for a wide range of field and temperature. The full thermally activated creep motion, observed below the depinning threshold, is shown to be described by a unique universal energy barrier function. Our findings should be relevant for other systems whose dynamics can be modeled by elastic interfaces moving on disordered energy landscapes.

  2. Detection and tracking of human targets in indoor and urban environments using through-the-wall radar sensors

    NASA Astrophysics Data System (ADS)

    Radzicki, Vincent R.; Boutte, David; Taylor, Paul; Lee, Hua

    2017-05-01

    Radar based detection of human targets behind walls or in dense urban environments is an important technical challenge with many practical applications in security, defense, and disaster recovery. Radar reflections from a human can be orders of magnitude weaker than those from objects encountered in urban settings such as walls, cars, or possibly rubble after a disaster. Furthermore, these objects can act as secondary reflectors and produce multipath returns from a person. To mitigate these issues, processing of radar return data needs to be optimized for recognizing human motion features such as walking, running, or breathing. This paper presents a theoretical analysis on the modulation effects human motion has on the radar waveform and how high levels of multipath can distort these motion effects. From this analysis, an algorithm is designed and optimized for tracking human motion in heavily clutter environments. The tracking results will be used as the fundamental detection/classification tool to discriminate human targets from others by identifying human motion traits such as predictable walking patterns and periodicity in breathing rates. The theoretical formulations will be tested against simulation and measured data collected using a low power, portable see-through-the-wall radar system that could be practically deployed in real-world scenarios. Lastly, the performance of the algorithm is evaluated in a series of experiments where both a single person and multiple people are moving in an indoor, cluttered environment.

  3. Trying Physics: Analyzing the Motion of the Quickest Score in International Rugby

    ERIC Educational Resources Information Center

    Goff, John Eric; Lipscombe, Trevor Davis

    2015-01-01

    The hearts of sports fans were stirred recently by the fastest-ever try scored in international rugby. Welsh winger Dafydd Howells crossed the Fijian try line to score a mere six seconds after Angus O'Brien had started the game with a kickoff, in one of the fixtures in rugby's Junior World Cup played on June 2, 2014, in New Zealand. This…

  4. Patient motion effects on the quantification of regional myocardial blood flow with dynamic PET imaging.

    PubMed

    Hunter, Chad R R N; Klein, Ran; Beanlands, Rob S; deKemp, Robert A

    2016-04-01

    Patient motion is a common problem during dynamic positron emission tomography (PET) scans for quantification of myocardial blood flow (MBF). The purpose of this study was to quantify the prevalence of body motion in a clinical setting and evaluate with realistic phantoms the effects of motion on blood flow quantification, including CT attenuation correction (CTAC) artifacts that result from PET-CT misalignment. A cohort of 236 sequential patients was analyzed for patient motion under resting and peak stress conditions by two independent observers. The presence of motion, affected time-frames, and direction of motion was recorded; discrepancy between observers was resolved by consensus review. Based on these results, patient body motion effects on MBF quantification were characterized using the digital NURBS-based cardiac-torso phantom, with characteristic time activity curves (TACs) assigned to the heart wall (myocardium) and blood regions. Simulated projection data were corrected for attenuation and reconstructed using filtered back-projection. All simulations were performed without noise added, and a single CT image was used for attenuation correction and aligned to the early- or late-frame PET images. In the patient cohort, mild motion of 0.5 ± 0.1 cm occurred in 24% and moderate motion of 1.0 ± 0.3 cm occurred in 38% of patients. Motion in the superior/inferior direction accounted for 45% of all detected motion, with 30% in the superior direction. Anterior/posterior motion was predominant (29%) in the posterior direction. Left/right motion occurred in 24% of cases, with similar proportions in the left and right directions. Computer simulation studies indicated that errors in MBF can approach 500% for scans with severe patient motion (up to 2 cm). The largest errors occurred when the heart wall was shifted left toward the adjacent lung region, resulting in a severe undercorrection for attenuation of the heart wall. Simulations also indicated that the

  5. Patient motion effects on the quantification of regional myocardial blood flow with dynamic PET imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hunter, Chad R. R. N.; Kemp, Robert A. de, E-mail: RAdeKemp@ottawaheart.ca; Klein, Ran

    Purpose: Patient motion is a common problem during dynamic positron emission tomography (PET) scans for quantification of myocardial blood flow (MBF). The purpose of this study was to quantify the prevalence of body motion in a clinical setting and evaluate with realistic phantoms the effects of motion on blood flow quantification, including CT attenuation correction (CTAC) artifacts that result from PET–CT misalignment. Methods: A cohort of 236 sequential patients was analyzed for patient motion under resting and peak stress conditions by two independent observers. The presence of motion, affected time-frames, and direction of motion was recorded; discrepancy between observers wasmore » resolved by consensus review. Based on these results, patient body motion effects on MBF quantification were characterized using the digital NURBS-based cardiac-torso phantom, with characteristic time activity curves (TACs) assigned to the heart wall (myocardium) and blood regions. Simulated projection data were corrected for attenuation and reconstructed using filtered back-projection. All simulations were performed without noise added, and a single CT image was used for attenuation correction and aligned to the early- or late-frame PET images. Results: In the patient cohort, mild motion of 0.5 ± 0.1 cm occurred in 24% and moderate motion of 1.0 ± 0.3 cm occurred in 38% of patients. Motion in the superior/inferior direction accounted for 45% of all detected motion, with 30% in the superior direction. Anterior/posterior motion was predominant (29%) in the posterior direction. Left/right motion occurred in 24% of cases, with similar proportions in the left and right directions. Computer simulation studies indicated that errors in MBF can approach 500% for scans with severe patient motion (up to 2 cm). The largest errors occurred when the heart wall was shifted left toward the adjacent lung region, resulting in a severe undercorrection for attenuation of the heart wall

  6. Nanoparticle Brownian motion and hydrodynamic interactions in the presence of flow fields

    PubMed Central

    Uma, B.; Swaminathan, T. N.; Radhakrishnan, R.; Eckmann, D. M.; Ayyaswamy, P. S.

    2011-01-01

    We consider the Brownian motion of a nanoparticle in an incompressible Newtonian fluid medium (quiescent or fully developed Poiseuille flow) with the fluctuating hydrodynamics approach. The formalism considers situations where both the Brownian motion and the hydrodynamic interactions are important. The flow results have been modified to account for compressibility effects. Different nanoparticle sizes and nearly neutrally buoyant particle densities are also considered. Tracked particles are initially located at various distances from the bounding wall to delineate wall effects. The results for thermal equilibrium are validated by comparing the predictions for the temperatures of the particle with those obtained from the equipartition theorem. The nature of the hydrodynamic interactions is verified by comparing the velocity autocorrelation functions and mean square displacements with analytical and experimental results where available. The equipartition theorem for a Brownian particle in Poiseuille flow is verified for a range of low Reynolds numbers. Numerical predictions of wall interactions with the particle in terms of particle diffusivities are consistent with results, where available. PMID:21918592

  7. Large- and Very-Large-Scale Motions in Katabatic Flows Over Steep Slopes

    NASA Astrophysics Data System (ADS)

    Giometto, M. G.; Fang, J.; Salesky, S.; Parlange, M. B.

    2016-12-01

    Evidence of large- and very-large-scale motions populating the boundary layer in katabatic flows over steep slopes is presented via direct numerical simulations (DNSs). DNSs are performed at a modified Reynolds number (Rem = 967), considering four sloping angles (α = 60°, 70°, 80° and 90°). Large coherent structures prove to be strongly dependent on the inclination of the underlying surface. Spectra and co-spectra consistently show signatures of large-scale motions (LSMs), with streamwise extension on the order of the boundary layer thickness. A second low-wavenumber mode characterizes pre-multiplied spectra and co-spectra when the slope angle is below 70°, indicative of very-large-scale motions (VLSMs). In addition, conditional sampling and averaging shows how LSMs and VLSMs are induced by counter-rotating roll modes, in agreement with findings from canonical wall-bounded flows. VLSMs contribute to the stream-wise velocity variance and shear stress in the above-jet regions up to 30% and 45% respectively, whereas both LSMs and VLSMs are inactive in the near-wall regions.

  8. Self-sustaining processes at all scales in wall-bounded turbulent shear flows

    NASA Astrophysics Data System (ADS)

    Cossu, Carlo; Hwang, Yongyun

    2017-03-01

    We collect and discuss the results of our recent studies which show evidence of the existence of a whole family of self-sustaining motions in wall-bounded turbulent shear flows with scales ranging from those of buffer-layer streaks to those of large-scale and very-large-scale motions in the outer layer. The statistical and dynamical features of this family of self-sustaining motions, which are associated with streaks and quasi-streamwise vortices, are consistent with those of Townsend's attached eddies. Motions at each relevant scale are able to sustain themselves in the absence of forcing from larger- or smaller-scale motions by extracting energy from the mean flow via a coherent lift-up effect. The coherent self-sustaining process is embedded in a set of invariant solutions of the filtered Navier-Stokes equations which take into full account the Reynolds stresses associated with the residual smaller-scale motions.

  9. Domain wall assisted GMR head with spin-Hall effect

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arun, R., E-mail: arunbdu@gmail.com; Sabareesan, P., E-mail: sendtosabari@gmail.com; Daniel, M., E-mail: danielcnld@gmail.com

    2016-05-06

    We theoretically study the dynamics of a field induced domain wall in the Py/Pt bi-layer structure in the presence of spin-Hall effect (SHE) by solving the Landau-Lifshitz-Gilbert (LLG) equation along with the adiabatic, nonadiabatic and SHE spin-transfer torques (STTs). It is observed that a weak magnetic field moves the domain wall with high velocity in the presence of SHE and the direction of the velocity is changed by changing the direction of the weak field. The numerical results show that the magnetization of the ferromagnetic layer can be reversed quickly through domain wall motion by changing the direction of amore » weak external field in the presence of SHE while the direction of current is fixed. The SHE reduces the magnetization reversal time of 1000 nm length strip by 14.7 ns. This study is extended to model a domain wall based GMR (Giant Magnetoresistance) read head with SHE.« less

  10. SVM-based classification of LV wall motion in cardiac MRI with the assessment of STE

    NASA Astrophysics Data System (ADS)

    Mantilla, Juan; Garreau, Mireille; Bellanger, Jean-Jacques; Paredes, José Luis

    2015-01-01

    In this paper, we propose an automated method to classify normal/abnormal wall motion in Left Ventricle (LV) function in cardiac cine-Magnetic Resonance Imaging (MRI), taking as reference, strain information obtained from 2D Speckle Tracking Echocardiography (STE). Without the need of pre-processing and by exploiting all the images acquired during a cardiac cycle, spatio-temporal profiles are extracted from a subset of radial lines from the ventricle centroid to points outside the epicardial border. Classical Support Vector Machines (SVM) are used to classify features extracted from gray levels of the spatio-temporal profile as well as their representations in the Wavelet domain under the assumption that the data may be sparse in that domain. Based on information obtained from radial strain curves in 2D-STE studies, we label all the spatio-temporal profiles that belong to a particular segment as normal if the peak systolic radial strain curve of this segment presents normal kinesis, or abnormal if the peak systolic radial strain curve presents hypokinesis or akinesis. For this study, short-axis cine- MR images are collected from 9 patients with cardiac dyssynchrony for which we have the radial strain tracings at the mid-papilary muscle obtained by 2D STE; and from one control group formed by 9 healthy subjects. The best classification performance is obtained with the gray level information of the spatio-temporal profiles using a RBF kernel with 91.88% of accuracy, 92.75% of sensitivity and 91.52% of specificity.

  11. Free-breathing black-blood CINE fast-spin echo imaging for measuring abdominal aortic wall distensibility: a feasibility study

    NASA Astrophysics Data System (ADS)

    Lin, Jyh-Miin; Patterson, Andrew J.; Chao, Tzu-Cheng; Zhu, Chengcheng; Chang, Hing-Chiu; Mendes, Jason; Chung, Hsiao-Wen; Gillard, Jonathan H.; Graves, Martin J.

    2017-05-01

    The paper reports a free-breathing black-blood CINE fast-spin echo (FSE) technique for measuring abdominal aortic wall motion. The free-breathing CINE FSE includes the following MR techniques: (1) variable-density sampling with fast iterative reconstruction; (2) inner-volume imaging; and (3) a blood-suppression preparation pulse. The proposed technique was evaluated in eight healthy subjects. The inner-volume imaging significantly reduced the intraluminal artifacts of respiratory motion (p  =  0.015). The quantitative measurements were a diameter of 16.3  ±  2.8 mm and wall distensibility of 2.0  ±  0.4 mm (12.5  ±  3.4%) and 0.7  ±  0.3 mm (4.1  ±  1.0%) for the anterior and posterior walls, respectively. The cyclic cross-sectional distensibility was 35  ±  15% greater in the systolic phase than in the diastolic phase. In conclusion, we developed a feasible CINE FSE method to measure the motion of the abdominal aortic wall, which will enable clinical scientists to study the elasticity of the abdominal aorta.

  12. Clinical score and arterial oxygen saturation in children with wheezing associated respiratory illness (WARI).

    PubMed

    Sritippayawan, S; Deerojanawong, J; Prapphal, N

    2000-10-01

    To determine the correlation between clinical score (based on respiratory rate, chest wall retractions, air entry, wheezing, consciousness and audible wheezing) and arterial oxygen saturation (SaO2: measured by pulse oximetry) as well as the most appropriate total score for predicting hypoxemia (SaO2 < or = 95%) in children diagnosed to have wheezing associated respiratory illness (WARI). 70 children (1 month-5 years old) hospitalized in the Department of Pediatrics, Chulalongkorn Hospital with the diagnosis of WARI from January 1, 1996 to December 31, 1996 were studied. Half of them were diagnosed to have acute lower respiratory tract infection (LRI) with wheezing while the remainder had reactive airway disease (RAD). Cross sectional, analytical study. In each group of patients, the clinical score and SaO2 were assessed by the same pediatrician throughout the study. The correlation between the clinical signs and SaO2 as well as the cut off point of total score for predicting hypoxemia were analyzed. The sensitivity, specificity and accuracy of that total score in predicting hypoxemia were also calculated. In both groups of patients (acute LRI with wheezing and RAD group), the clinical signs correlated with SaO2 were wheezing (rs = -0.67 and -0.47 respectively) and chest wall retractions (rs = -0.57 and -0.59 respectively). Total score was also correlated with SaO2 (rs = -0.68 and -0.5 respectively). The cut off point of total score in predicting hypoxemia was 4 providing 80 per cent sensitivity in both groups with accuracy 74.3 per cent and 80 per cent respectively. This clinical score may be used to assess the severity of hypoxemia in WARI patients. Wheezing, chest wall retractions and total score correlated well with SaO2. The total score > 4 was most appropriate in predicting hypoxemia in both children with RAD and wheezing associated with LRI.

  13. Control of self-motion in dynamic fluids: fish do it differently from bees.

    PubMed

    Scholtyssek, Christine; Dacke, Marie; Kröger, Ronald; Baird, Emily

    2014-05-01

    To detect and avoid collisions, animals need to perceive and control the distance and the speed with which they are moving relative to obstacles. This is especially challenging for swimming and flying animals that must control movement in a dynamic fluid without reference from physical contact to the ground. Flying animals primarily rely on optic flow to control flight speed and distance to obstacles. Here, we investigate whether swimming animals use similar strategies for self-motion control to flying animals by directly comparing the trajectories of zebrafish (Danio rerio) and bumblebees (Bombus terrestris) moving through the same experimental tunnel. While moving through the tunnel, black and white patterns produced (i) strong horizontal optic flow cues on both walls, (ii) weak horizontal optic flow cues on both walls and (iii) strong optic flow cues on one wall and weak optic flow cues on the other. We find that the mean speed of zebrafish does not depend on the amount of optic flow perceived from the walls. We further show that zebrafish, unlike bumblebees, move closer to the wall that provides the strongest visual feedback. This unexpected preference for strong optic flow cues may reflect an adaptation for self-motion control in water or in environments where visibility is limited. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  14. Hydrodynamic Trapping of Swimming Bacteria by Convex Walls

    NASA Astrophysics Data System (ADS)

    Sipos, O.; Nagy, K.; Di Leonardo, R.; Galajda, P.

    2015-06-01

    Swimming bacteria display a remarkable tendency to move along flat surfaces for prolonged times. This behavior may have a biological importance but can also be exploited by using microfabricated structures to manipulate bacteria. The main physical mechanism behind the surface entrapment of swimming bacteria is, however, still an open question. By studying the swimming motion of Escherichia coli cells near microfabricated pillars of variable size, we show that cell entrapment is also present for convex walls of sufficiently low curvature. Entrapment is, however, markedly reduced below a characteristic radius. Using a simple hydrodynamic model, we predict that trapped cells swim at a finite angle with the wall and a precise relation exists between the swimming angle at a flat wall and the critical radius of curvature for entrapment. Both predictions are quantitatively verified by experimental data. Our results demonstrate that the main mechanism for wall entrapment is hydrodynamic in nature and show the possibility of inhibiting cell adhesion, and thus biofilm formation, using convex features of appropriate curvature.

  15. Domain wall motion and electromechanical strain in lead-free piezoelectrics: Insight from the model system (1 − x)Ba(Zr{sub 0.2}Ti{sub 0.8})O{sub 3}–x(Ba{sub 0.7}Ca{sub 0.3})TiO{sub 3} using in situ high-energy X-ray diffraction during application of electric fields

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tutuncu, Goknur; Li, Binzhi; Bowman, Keith

    The piezoelectric compositions (1 − x)Ba(Zr{sub 0.2}Ti{sub 0.8})O{sub 3}–x(Ba{sub 0.7}Ca{sub 0.3})TiO{sub 3} (BZT-xBCT) span a model lead-free morphotropic phase boundary (MPB) between room temperature rhombohedral and tetragonal phases at approximately x = 0.5. In the present work, in situ X-ray diffraction measurements during electric field application are used to elucidate the origin of electromechanical strain in several compositions spanning the tetragonal compositional range 0.6 ≤ x ≤ 0.9. As BCT concentration decreases towards the MPB, the tetragonal distortion (given by c/a-1) decreases concomitantly with an increase in 90° domain wall motion. The increase in observed macroscopic strain is predominantly attributed to the increased contribution from 90°more » domain wall motion. The results demonstrate that domain wall motion is a significant factor in achieving high strain and piezoelectric coefficients in lead-free polycrystalline piezoelectrics.« less

  16. Measurement of Zeta-Potential at Microchannel Wall by a Nanoscale Laser Induced Fluorescence Imaging

    NASA Astrophysics Data System (ADS)

    Kazoe, Yutaka; Sato, Yohei

    A nanoscale laser induced fluorescence imaging was proposed by using fluorescent dye and the evanescent wave with total internal reflection of a laser beam. The present study focused on the two-dimensional measurement of zeta-potential at the microchannel wall, which is an electrostatic potential at the wall surface and a dominant parameter of electroosmotic flow. The evanescent wave, which decays exponentially from the wall, was used as an excitation light of the fluorescent dye. The fluorescent intensity detected by a CCD camera is closely related to the zeta-potential. Two kinds of fluorescent dye solution at different ionic concentrations were injected into a T-shaped microchannel, and formed a mixing flow field in the junction area. The two-dimensional distribution of zeta-potential at the microchannel wall in the pressure-driven flow field was measured. The obtained zeta-potential distribution has a transverse gradient toward the mixing flow field and was changed by the difference in the averaged velocity of pressure-driven flow. To understand the ion motion in the mixing flow field, the three-dimensional flow structure was analyzed by the velocity measurement using micron-resolution particle image velocimetry and the numerical simulation. It is concluded that the two-dimensional distribution of zeta-potential at the microchannel wall was dependent on the ion motion in the flow field, which was governed by the convection and molecular diffusion.

  17. Driving mechanism of unsteady separation shock motion in hypersonic interactive flow

    NASA Technical Reports Server (NTRS)

    Dolling, D. S.; Narlo, J. C., II

    1987-01-01

    Wall pressure fluctuations were measured under the steady separation shock waves in Mach 5 turbulent interactions induced by unswept circular cylinders on a flat plate. The wall temperature was adiabatic. A conditional sampling algorithm was developed to examine the statistics of the shock wave motion. The same algorithm was used to examine data taken in earlier studies in the Princeton University Mach 3 blowdown tunnel. In these earlier studies, hemicylindrically blunted fins of different leading-edge diameters were tested in boundary layers which developed on the tunnel floor and on a flat plate. A description of the algorithm, the reasons why it was developed and the sensitivity of the results to the threshold settings, are discussed. The results from the algorithm, together with cross correlations and power spectral density estimates suggests that the shock motion is driven by the low-frequency unsteadiness of the downstream separated, vortical flow.

  18. Fluid-structure interaction simulations of the Fontan procedure using variable wall properties.

    PubMed

    Long, C C; Hsu, M-C; Bazilevs, Y; Feinstein, J A; Marsden, A L

    2012-05-01

    Children born with single ventricle heart defects typically undergo a staged surgical procedure culminating in a total cavopulmonary connection (TCPC) or Fontan surgery. The goal of this work was to perform physiologic, patient-specific hemodynamic simulations of two post-operative TCPC patients by using fluid-structure interaction (FSI) simulations. Data from two patients are presented, and post-op anatomy is reconstructed from MRI data. Respiration rate, heart rate, and venous pressures are obtained from catheterization data, and inflow rates are obtained from phase contrast MRI data and are used together with a respiratory model. Lumped parameter (Windkessel) boundary conditions are used at the outlets. We perform FSI simulations by using an arbitrary Lagrangian-Eulerian finite element framework to account for motion of the blood vessel walls in the TCPC. This study is the first to introduce variable elastic properties for the different areas of the TCPC, including a Gore-Tex conduit. Quantities such as wall shear stresses and pressures at critical locations are extracted from the simulation and are compared with pressure tracings from clinical data as well as with rigid wall simulations. Hepatic flow distribution and energy efficiency are also calculated and compared for all cases. There is little effect of FSI on pressure tracings, hepatic flow distribution, and time-averaged energy efficiency. However, the effect of FSI on wall shear stress, instantaneous energy efficiency, and wall motion is significant and should be considered in future work, particularly for accurate prediction of thrombus formation. Copyright © 2012 John Wiley & Sons, Ltd.

  19. Early Versus Late Weight-Bearing Protocols for Surgically Managed Posterior Wall Acetabular Fractures.

    PubMed

    Heare, Austin; Kramer, Nicholas; Salib, Christopher; Mauffrey, Cyril

    2017-07-01

    Despite overall improved outcomes with open reduction and internal fixation of acetabular fractures, posterior wall fractures show disproportionately poor results. The effect of weight bearing on outcomes of fracture management has been investigated in many lower extremity fractures, but evidence-based recommendations in posterior wall acetabular fractures are lacking. The authors systematically reviewed the current literature to determine if a difference in outcome exists between early and late postoperative weight-bearing protocols for surgically managed posterior wall acetabular fractures. PubMed and MEDLINE were searched for posterior wall acetabular fracture studies that included weight-bearing protocols and Merle d'Aubigné functional scores. Twelve studies were identified. Each study was classified as either early or late weight bearing. Early weight bearing was defined as full, unrestricted weight bearing at or before 12 weeks postoperatively. Late weight bearing was defined as restricted weight bearing for greater than 12 weeks postoperatively. The 2 categories were then compared by functional score using a 2-tailed t test and by complication rate using chi-square analysis. Six studies (152 fractures) were placed in the early weight-bearing category. Six studies (302 fractures) were placed in the late weight-bearing category. No significant difference in Merle d'Aubigné functional scores was found between the 2 groups. No difference was found regarding heterotopic ossification, avascular necrosis, superficial infections, total infections, or osteoarthritis. This systematic review found no difference in functional outcome scores or complication rates between early and late weight-bearing protocols for surgically treated posterior wall fractures. [Orthopedics. 2017: 40(4):e652-e657.]. Copyright 2017, SLACK Incorporated.

  20. Current induced vortex wall dynamics in helical magnetic systems

    NASA Astrophysics Data System (ADS)

    Roostaei, Bahman

    2015-03-01

    Nontrivial topology of interfaces separating phases with opposite chirality in helical magnetic metals result in new effects as they interact with spin polarized current. These interfaces or vortex walls consist of a one dimensional array of vortex lines. We predict that adiabatic transfer of angular momentum between vortex array and spin polarized current will result in topological Hall effect in multi-domain samples. Also we predict that the motion of the vortex array will result in a new damping mechanism for magnetic moments based on Lenz's law. We study the dynamics of these walls interacting with electric current and use fundamental electromagnetic laws to quantify those predictions. On the other hand discrete nature of vortex walls affects their pinning and results in low depinning current density. We predict the value of this current using collective pinning theory.

  1. A numerical simulation of peristaltic motion in the ureter using fluid structure interactions.

    PubMed

    Vahidi, Bahman; Fatouraee, Nasser

    2007-01-01

    An axisymmetric model with fluid-structure interactions (FSI) is introduced and solved to perform ureter flow and stress analysis. The Navier-Stokes equations are solved for the fluid and a linear elastic model for ureter is used. The finite element equations for both the structure and the fluid were solved by the Newton-Raphson iterative method. Our results indicated that shear stresses were high around the throat of moving contracted wall. The pressure gradient magnitude along the ureter wall and the symmetry line had the maximum value around the throat of moving contracted wall which decreased as the peristalsis propagates toward the bladder. The flow rate at the ureter outlet at the end of the peristaltic motion was about 650 mm3/s. During propagation of the peristalsis toward the bladder, the inlet backward flow region was limited to the areas near symmetry line but the inner ureter backward flow regions extended to the whole ureter contraction part. The backward flow was vanished after 1.5 seconds of peristalsis propagation start up and after that time the urine flow was forward in the whole ureter length, so reflux is more probable to be present at the beginning of the wall peristaltic motion.

  2. Gravity-induced dynamics of a squirmer microswimmer in wall proximity

    NASA Astrophysics Data System (ADS)

    Rühle, Felix; Blaschke, Johannes; Kuhr, Jan-Timm; Stark, Holger

    2018-02-01

    We perform hydrodynamic simulations using the method of multi-particle collision dynamics and a theoretical analysis to study a single squirmer microswimmer at high Péclet number, which moves in a low Reynolds number fluid and under gravity. The relevant parameters are the ratio α of swimming to bulk sedimentation velocity and the squirmer type β. The combination of self-propulsion, gravitational force, hydrodynamic interactions with the wall, and thermal noise leads to a surprisingly diverse behavior. At α > 1 we observe cruising states, while for α < 1 the squirmer resides close to the bottom wall with the motional state determined by stable fixed points in height and orientation. They strongly depend on the squirmer type β. While neutral squirmers permanently float above the wall with upright orientation, pullers float for α larger than a threshold value {α }th} and are pinned to the wall below {α }th}. In contrast, pushers slide along the wall at lower heights, from which thermal orientational fluctuations drive them into a recurrent floating state with upright orientation, where they remain on the timescale of orientational persistence.

  3. Dynamics of a Sliding Ladder Leaning against a Wall

    ERIC Educational Resources Information Center

    Oliveira, J. B.; Simeão Carvalho, P.; Mota, M. F.; Quintas, M. J.

    2015-01-01

    This study is about the dynamics of a sliding ladder leaning against a vertical wall. The results are understood by considering the motion divided in two parts: (i) for 0 = t = t[subscript s] with one degree of freedom, and (ii) for t > t[subscript s] with two degrees of freedom, where the separation is determined by the instance t[subscript…

  4. Switching by Domain-Wall Automotion in Asymmetric Ferromagnetic Rings

    NASA Astrophysics Data System (ADS)

    Mawass, Mohamad-Assaad; Richter, Kornel; Bisig, Andre; Reeve, Robert M.; Krüger, Benjamin; Weigand, Markus; Stoll, Hermann; Krone, Andrea; Kronast, Florian; Schütz, Gisela; Kläui, Mathias

    2017-04-01

    Spintronic applications based on magnetic domain-wall (DW) motion, such as magnetic data storage, sensors, and logic devices, require approaches to reliably manipulate the magnetization in nanowires. In this paper, we report the direct dynamic experimental visualization of reliable switching from the onion to the vortex state by DW automotion at zero field in asymmetric ferromagnetic rings using a uniaxial field pulse. Employing time-resolved x-ray microscopy, we demonstrate that depending on the detailed spin structure of the DWs and the size and geometry of the rings, the automotive propagation can be tailored during the DW relaxation from the higher-energy onion state to the energetically favored vortex state, where both DWs annihilate. Our measurements show DW automotion with an average velocity of about 60 m /s , which is a significant speed for spintronic devices. Such motion is mostly governed by local forces resulting from the geometry variations in the device. A closer study of the annihilation process via micromagnetic simulations reveals that a new vortex is nucleated in between the two initial walls. We demonstrate that the annihilation of DWs through automotion in our scheme always occurs with the detailed topological nature of the walls influencing only the DW dynamics on a local scale. The simulations show good quantitative agreement with our experimental results. These findings shed light on a robust and reliable switching process of the onion state in ferromagnetic rings, which paves the way for further optimization of these devices.

  5. Wall strains produced by waves in water filled latex tubes. Part 1: Tethered tubes

    NASA Astrophysics Data System (ADS)

    Gerrard, J. H.

    1992-05-01

    A progress report on measurements of wall strain is presented. The experimental aim is to produce data with which to compare the results of numerical analysis of pulsatile flow in a deformable tube. The computation is a difficult job requiring the solution of the wall and fluid equations and matching them at the interface which moves. The simplest arrangement of a straight distensible tube attached to a rigid tube of the same internal diameter in which a piston starts from rest was consequently chosen. The rubber tube is of finite length and closed and fixed at the far end. Two forms of motion are examined, sinusoidal motion from rest and impulsive motion in which the piston moves a short distance and stops. The simpler case considered is a tethered tube which only executes radial motion; in the second case the horizontal tube is suspended by cotton threads so that it is free to move longitudinally as well. Measurements of the longitudinal and circumferential strains as a function of distance along the tube were made. The measurements were made at low and high frequency and with short and long tubes. With long tubes the end effect can be investigated. The treatment of shorter tubes by numerical analysis present less of a storage problem.

  6. Various anti-motion sickness drugs and core body temperature changes.

    PubMed

    Cheung, Bob; Nakashima, Ann M; Hofer, Kevin D

    2011-04-01

    Blood flow changes and inactivity associated with motion sickness appear to exacerbate the rate of core temperature decrease during subsequent body cooling. We investigated the effects of various classes of anti-motion sickness drugs on core temperature changes. There were 12 healthy male and female subjects (20-35 yr old) who were given selected classes of anti-motion sickness drugs prior to vestibular Coriolis cross coupling induced by graded yaw rotation and periodic pitch-forward head movements in the sagittal plane. All subjects were then immersed in water at 18 degrees C for a maximum of 90 min or until their core temperature reached 35 degrees C. Double-blind randomized trials were administered, including a placebo, a non-immersion control with no drug, and six anti-motion sickness drugs: meclizine, dimenhydrinate, chlorpheniramine, promethazine + dexamphetamine, promethazine + caffeine, and scopolamine + dexamphetamine. A 7-d washout period was observed between trials. Core temperature and the severity of sickness were monitored throughout each trial. A repeated measures design was performed on the severity of sickness and core temperature changes prior to motion provocation, immediately after the motion sickness end point, and throughout the period of cold-water immersion. The most effective anti-motion sickness drugs, promethazine + dexamphetamine (with a sickness score/duration of 0.65 +/- 0.17) and scopolamine + dexamphetamine (with a sickness score/duration of 0.79 +/- 0.17), significantly attenuated the decrease in core temperature. The effect of this attenuation was lower in less effective drugs. Our results suggest that the two most effective anti-motion sickness drugs are also the most effective in attenuating the rate of core temperature decrease.

  7. Active Brownian particles near straight or curved walls: Pressure and boundary layers

    NASA Astrophysics Data System (ADS)

    Duzgun, Ayhan; Selinger, Jonathan V.

    2018-03-01

    Unlike equilibrium systems, active matter is not governed by the conventional laws of thermodynamics. Through a series of analytic calculations and Langevin dynamics simulations, we explore how systems cross over from equilibrium to active behavior as the activity is increased. In particular, we calculate the profiles of density and orientational order near straight or circular walls and show the characteristic width of the boundary layers. We find a simple relationship between the enhancements of density and pressure near a wall. Based on these results, we determine how the pressure depends on wall curvature and hence make approximate analytic predictions for the motion of curved tracers, as well as the rectification of active particles around small openings in confined geometries.

  8. Effect of Rotation on Scaffold Motion and Cell Growth in Rotating Bioreactors.

    PubMed

    Varley, Mark C; Markaki, Athina E; Brooks, Roger A

    2017-06-01

    Efficient use of different bioreactor designs to improve cell growth in three-dimensional scaffolds requires an understanding of their mechanism of action. To address this for rotating wall vessel bioreactors, fluid and scaffold motion were investigated experimentally at different rotation speeds and vessel fill volumes. Low cost bioreactors with single and dual axis rotation were developed to investigate the effect of these systems on human osteoblast proliferation in free floating and constrained collagen-glycosaminoglycan porous scaffolds. A range of scaffold motions (free fall, periodic oscillation, and orbital motion) were observed at the rotation speeds and vessel fluid/air ratios used, with 85% fluid fill and an outer vessel wall velocity of ∼14 mm s -1 producing a scaffold in a free fall state. The cell proliferation results showed that after 14 and 21 days of culture, this combination of fluid fill and speed of rotation produced significantly greater cell numbers in the scaffolds than when lower or higher rotation speeds (p < 0.002) or when the chamber was 60% or 100% full (p < 0.01). The fluid flow and scaffold motion experiments show that biaxial rotation would not improve the mass transfer of medium into the scaffold as the second axis of rotation can only transition the scaffold toward oscillatory or orbital motion and, hence, reduce mass transport to the scaffold. The cell culture results confirmed that there was no benefit to the second axis of rotation with no significant difference in cell proliferation either when the scaffolds were free floating or constrained (p > 0.05).

  9. Effect of Rotation on Scaffold Motion and Cell Growth in Rotating Bioreactors

    PubMed Central

    Varley, Mark C.; Markaki, Athina E.

    2017-01-01

    Efficient use of different bioreactor designs to improve cell growth in three-dimensional scaffolds requires an understanding of their mechanism of action. To address this for rotating wall vessel bioreactors, fluid and scaffold motion were investigated experimentally at different rotation speeds and vessel fill volumes. Low cost bioreactors with single and dual axis rotation were developed to investigate the effect of these systems on human osteoblast proliferation in free floating and constrained collagen-glycosaminoglycan porous scaffolds. A range of scaffold motions (free fall, periodic oscillation, and orbital motion) were observed at the rotation speeds and vessel fluid/air ratios used, with 85% fluid fill and an outer vessel wall velocity of ∼14 mm s−1 producing a scaffold in a free fall state. The cell proliferation results showed that after 14 and 21 days of culture, this combination of fluid fill and speed of rotation produced significantly greater cell numbers in the scaffolds than when lower or higher rotation speeds (p < 0.002) or when the chamber was 60% or 100% full (p < 0.01). The fluid flow and scaffold motion experiments show that biaxial rotation would not improve the mass transfer of medium into the scaffold as the second axis of rotation can only transition the scaffold toward oscillatory or orbital motion and, hence, reduce mass transport to the scaffold. The cell culture results confirmed that there was no benefit to the second axis of rotation with no significant difference in cell proliferation either when the scaffolds were free floating or constrained (p > 0.05). PMID:28125920

  10. Streaks and vortices in near-wall turbulence.

    PubMed

    Chernyshenko, S I; Baig, M F

    2005-05-15

    This paper presents evidence that organization of wall-normal motions plays almost no role in the creation of streaks. This evidence consists of the theory of streak generation not requiring the existence of organized vortices, extensive quantitative comparisons between the theory and direct numerical simulations, including examples of large variation in average spacing of the streaks of different scalars simultaneously present in the flow, and an example of the scalar streaks in an artificially created purely random flow.

  11. Domain Wall Evolution in Phase Transforming Oxides

    DTIC Science & Technology

    2015-01-14

    configumtions under driving forces (e.g. changes in temperature and electric fields) in an effort to: 1) understand the underlying linkage between -1...configurations under driving forces (e.g. changes in temperature and electric fields) in an effort to: 1) understand the underlying linkage between...Extensive domain wall motion and deaging resistance in morphotropic 0.55Bi(Ni1/2Ti1/2)O3–0.45PbTiO3 polycrystalline ferroelectrics, Applied Physics Letters

  12. Trying Physics: Analyzing the Motion of the Quickest Score in International Rugby

    NASA Astrophysics Data System (ADS)

    Goff, John Eric; Lipscombe, Trevor Davis

    2015-02-01

    The hearts of sports fans were stirred recently by the fastest-ever try scored in international rugby. Welsh winger Dafydd Howells crossed the Fijian try line to score a mere six seconds after Angus O'Brien had started the game with a kickoff, in one of the fixtures in rugby's Junior World Cup played on June 2, 2014, in New Zealand. This startlingly quick score, though, is of interest to physics players as well as rugby players. Howells' try serves as an intriguing way to involve students in one of the "core competencies" of physicists—to model events in the real world. And with the Rugby World Cup taking place in 2015 in England, and rugby sevens making its debut in the 2016 Summer Olympics in Brazil (U.S. teams have qualified for both events), rugby is increasing in popularity in America and is even gaining some coverage on television. Thanks to You-Tube, Howells' try is readily available to serve as a laboratory experiment for students to analyze.

  13. [Myocardial imaging in acute myocardial infarction using beta-methyl-p-(123I)-iodophenylpentadecanoic acid: comparison with 201Tl imaging and wall motion].

    PubMed

    Naruse, H; Itano, M; Kondo, T; Kogame, T; Yamamoto, J; Morita, M; Kawamoto, H; Fukutake, N; Ohyanagi, M; Iwasaki, T

    1992-01-01

    Myocardial imaging using beta-methyl-p-(123I)-iodophenylpentadecanoic acid (BMIPP) was performed in 11 patients with acute myocardial infarction. The left ventricular images were divided into 12 segments, and myocardial imagings with BMIPP were compared with coronary angiography (CAG), thallium-201 myocardial scintigraphy (TL) and wall motion obtained by two-dimensional echocardiography (WM). When the culprit lesion was at the proximal point of the left anterior descending artery (LAD), all segments showed depressed uptake. In 3 cases with single vessel disease of the LAD, inferior wall of the basis showed reduced uptake of BMIPP despite the location of the culprit lesion. In cases with discordant uptake between the two tracers, BMIPP frequently showed more severely depressed uptake than TL in the subacute phase, although the uptake of BMIPP correlated with that of TL (tau = 0.82, p less than 0.001). In such cases, the discordance was related to the improvement in WM from the acute phase to the convalescent phase. BMIPP uptake correlated with WM in the subacute phase (tau = 0.50, p less than 0.001). BMIPP showed more severely depressed uptake while WM showed mild asynergy in most cases in which discordance was found between the BMIPP and WM findings. However, there was no correlation between the change in WM from the acute to subacute phases, or the uptakes of BMIPP and TL alone. We concluded that the myocardial condition can be evaluated in detail in acute myocardial infarction by comparing the findings of BMIPP with those of TL and WM.

  14. Effects of Incentive Spirometry on Respiratory Motion in Healthy Subjects Using Cine Breathing Magnetic Resonance Imaging.

    PubMed

    Kotani, Toshiaki; Akazawa, Tsutomu; Sakuma, Tsuyoshi; Nagaya, Shigeyuki; Sonoda, Masaru; Tanaka, Yuji; Katogi, Takehide; Nemoto, Tetsuharu; Minami, Shohei

    2015-06-01

    To investigate the effectiveness of incentive spirometry on respiratory motion in healthy subjects using cine breathing magnetic resonance imaging (MRI). Ten non-smoking healthy subjects without any history of respiratory disease were studied. Subjects were asked to perform pulmonary training using incentive spirometry every day for two weeks. To assess the effectiveness of this training, pulmonary function tests and cine breathing MRI were performed before starting pulmonary training and two weeks after its completion. After training, there were significant improvements in vital capacity (VC) from 3.58±0.8 L to 3.74±0.8 L and in %VC from 107.4±10.8 to 112.1±8.2. Significant changes were observed in the right diaphragm motion, right chest wall motion, and left chest wall motion, which were increased from 55.7±9.6 mm to 63.4±10.2 mm, from 15.6±6.1 mm to 23.4±10.4 mm, and from 16.3±7.6 mm to 22.0±9.8 mm, respectively. Two weeks of training using incentive spirometry provided improvements in pulmonary function and respiratory motion, which suggested that incentive spirometry may be a useful preoperative modality for improving pulmonary function during the perioperative period.

  15. Wing walls for enhancing the seismic performance of reinforced concrete frame structures

    NASA Astrophysics Data System (ADS)

    Yang, Weisong; Guo, Xun; Xu, Weixiao; Yuan, Xin

    2016-06-01

    A building retrofitted with wing walls in the bottom story, which was damaged during the 2008 M8.0 Wenchuan earthquake in China, is introduced and a corresponding 1/4 scale wing wall-frame model was subjected to shake table motions to study the seismic behavior of this retrofitted structural system. The results show that wing walls can effectively protect columns from damage by moving areas that bear reciprocating tension and compression to the sections of the wing walls, thus achieving an extra measure of seismic fortification. A `strong column-weak beam' mechanism was realized, the flexural rigidity of the vertical member was strengthened, and a more uniform distribution of deformation among all the stories was measured. In addition, the joint between the wing walls and the beams suffered severe damage during the tests, due to an area of local stress concentration. A longer area of intensive stirrup is suggested in the end of the beams.

  16. Revised motion estimation algorithm for PROPELLER MRI.

    PubMed

    Pipe, James G; Gibbs, Wende N; Li, Zhiqiang; Karis, John P; Schar, Michael; Zwart, Nicholas R

    2014-08-01

    To introduce a new algorithm for estimating data shifts (used for both rotation and translation estimates) for motion-corrected PROPELLER MRI. The method estimates shifts for all blades jointly, emphasizing blade-pair correlations that are both strong and more robust to noise. The heads of three volunteers were scanned using a PROPELLER acquisition while they exhibited various amounts of motion. All data were reconstructed twice, using motion estimates from the original and new algorithm. Two radiologists independently and blindly compared 216 image pairs from these scans, ranking the left image as substantially better or worse than, slightly better or worse than, or equivalent to the right image. In the aggregate of 432 scores, the new method was judged substantially better than the old method 11 times, and was never judged substantially worse. The new algorithm compared favorably with the old in its ability to estimate bulk motion in a limited study of volunteer motion. A larger study of patients is planned for future work. Copyright © 2013 Wiley Periodicals, Inc.

  17. Impact of emphysema and airway wall thickness on quality of life in smoking-related COPD.

    PubMed

    Gietema, Hester A; Edwards, Lisa D; Coxson, Harvey O; Bakke, Per S

    2013-08-01

    Limited data are available as to the relationship between computed tomography (CT) derived data on emphysema and airway wall thickness, and quality of life in subjects with chronic obstructive pulmonary disease (COPD). Such data may work to clarify the clinical correlate of the CT findings. We included 1778 COPD subjects aged 40-75 years with a smoking history of at least 10 pack-years. They were examined with St George's Respiratory Questionnaire (SGRQ-C) and high-resolution chest CT. Level of emphysema was assessed as percent low-attenuation areas less than -950 Hounsfield units (%LAA). Airway wall thickness was estimated by calculating the square root of wall area of an imaginary airway with an internal perimeter of 10 mm (Pi10). In both men and women, the mean total score and most of the subscores of SGRQ-C increased with increasing level of emphysema and increasing level of airway wall thickness, after adjusting for age, smoking status, pack years, body mass index and FEV1. The highest gradient was seen in the relationship between the activity score and the emphysema level. The activity score increased by 35% from the lowest to the highest emphysema tertile. The relationship between level of emphysema and the total SGRQ-C score became weaker with increasing GOLD (Global initiative for Chronic Obstructive Lung Disease) stages (p < 0.001), while the impact of gender was limited. In subjects with COPD, increasing levels of emphysema and airway wall thickness are independently related to impaired quality of life. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Study on Combustion Characteristics and Propelling Projectile Motion Process of Bulk-Loaded Liquid Propellant

    NASA Astrophysics Data System (ADS)

    Xue, Xiaochun; Yu, Yonggang; Mang, Shanshan

    2017-07-01

    Data are presented showing that the problem of gas-liquid interaction instability is an important subject in the combustion and the propellant projectile motion process of a bulk-loaded liquid propellant gun (BLPG). The instabilities themselves arise from the sources, including fluid motion, to form a combustion gas cavity called Taylor cavity, fluid turbulence and breakup caused by liquid motion relative to the combustion chamber walls, and liquid surface breakup arising from a velocity mismatch on the gas-liquid interface. Typically, small disturbances that arise early in the BLPG combustion interior ballistic cycle can become amplified in the absence of burn rate limiting characteristics. Herein, significant attention has been given to developing and emphasizing the need for better combustion repeatability in the BLPG. Based on this goal, the concept of using different geometries of the combustion chamber is introduced and the concept of using a stepped-wall structure on the combustion chamber itself as a useful means of exerting boundary control on the combustion evolution to thus restrain the combustion instability has been verified experimentally in this work. Moreover, based on this background, the numerical simulation is devoted to a special combustion issue under transient high-pressure and high-temperature conditions, namely, studying the combustion mechanism in a stepped-wall combustion chamber with full monopropellant on one end that is stationary and the other end can move at high speed. The numerical results also show that the burning surface of the liquid propellant can be defined geometrically and combustion is well behaved as ignition and combustion progressivity are in a suitable range during each stage in this combustion chamber with a stepped-wall structure.

  19. Reynolds number scaling of straining motions in turbulence

    NASA Astrophysics Data System (ADS)

    Elsinga, Gerrit; Ishihara, T.; Goudar, M. V.; da Silva, C. B.; Hunt, J. C. R.

    2017-11-01

    Strain is an important fluid motion in turbulence as it is associated with the kinetic energy dissipation rate, vorticity stretching, and the dispersion of passive scalars. The present study investigates the scaling of the turbulent straining motions by evaluating the flow in the eigenframe of the local strain-rate tensor. The analysis is based on DNS of homogeneous isotropic turbulence covering a Reynolds number range Reλ = 34.6 - 1131. The resulting flow pattern reveals a shear layer containing tube-like vortices and a dissipation sheet, which both scale on the Kolmogorov length scale, η. The vorticity stretching motions scale on the Taylor length scale, while the flow outside the shear layer scales on the integral length scale. These scaling results are consistent with those in wall-bounded flow, which suggests a quantitative universality between the different flows. The overall coherence length of the vorticity is 120 η in all directions, which is considerably larger than the typical size of individual vortices, and reflects the importance of spatial organization at the small scales. Transitions in flow structure are identified at Reλ 45 and 250. Below these respective Reynolds numbers, the small-scale motions and the vorticity stretching motions appear underdeveloped.

  20. Morphologic study of three collagen materials for body wall repair.

    PubMed

    Soiderer, Emily E; Lantz, Gary C; Kazacos, Evelyn A; Hodde, Jason P; Wiegand, Ryan E

    2004-05-15

    The search for ideal prostheses for body wall repair continues. Synthetic materials such as polypropylene mesh (PPM) are associated with healing complications. A porcine-derived collagen-based material (CBM), small intestinal submucosa (SIS), has been studied for body wall repair. Renal capsule matrix (RCM) and urinary bladder submucosa (UBS) are CBMs not previously evaluated in this application. This is the first implant study using RCM. Full-thickness muscle/fascia ventral abdominal wall defects were repaired with SIS, RCM, UBS, and PPM in rats with omentum and omentectomy. A random complete block design was used to allot implant type to each of 96 rats. Healing was evaluated at 4 and 8 weeks. Adhesion tenacity and surface area were scored. Implant site dimensions were measured at implantation and necropsy. Inflammation, vascularization, and fibrosis were histopathologically scored. Data were compared by analysis of variance (P < 0.05). PPM produced a granulomatous foreign body response in contrast to the organized healing of CBM implants. CBM mean scores were lower than PPM scores for adhesion tenacity, surface area, and inflammation at each follow-up time for rats with omentums (P < 0.02). The CBMs had less tenacity and inflammation than PPM at each follow-up time in omentectomy groups (P < 0.008). Wound contraction was greater for PPM (P < 0.0001) for all rats. RCM and UBS were similar to SIS invoking reduced inflammation, adhesion, and contraction compared to PPM. The fibrotic response to PPM was unique and more intense compared to CBMs. These CBM implants appear morphologically acceptable and warrant continued investigation.

  1. Key features of hip hop dance motions affect evaluation by judges.

    PubMed

    Sato, Nahoko; Nunome, Hiroyuki; Ikegami, Yasuo

    2014-06-01

    The evaluation of hip hop dancers presently lacks clearly defined criteria and is often dependent on the subjective impressions of judges. Our study objective was to extract hidden motion characteristics that could potentially distinguish the skill levels of hip hop dancers and to examine the relationship between performance kinematics and judging scores. Eleven expert, six nonexpert, and nine novice dancers participated in the study, where each performed the "wave" motion as an experimental task. The movements of their upper extremities were captured by a motion capture system, and several kinematic parameters including the propagation velocity of the wave were calculated. Twelve judges evaluated the performances of the dancers, and we compared the kinematic parameters of the three groups and examined the relationship between the judging scores and the kinematic parameters. We found the coefficient of variation of the propagation velocity to be significantly different among the groups (P < .01) and highly correlated with the judging scores (r = -0.800, P < .01). This revealed that the variation of propagation velocity was the most dominant variable representing the skill level of the dancers and that the smooth propagation of the wave was most closely related to the evaluation by judges.

  2. Correlation between systolic transvalvular flow and proximal aortic wall changes in bicuspid aortic valve stenosis.

    PubMed

    Girdauskas, Evaldas; Rouman, Mina; Disha, Kushtrim; Scholle, Thorsten; Fey, Beatrix; Theis, Bernhard; Petersen, Iver; Borger, Michael A; Kuntze, Thomas

    2014-08-01

    The purpose of this study was to analyse the correlation between preoperative systolic transvalvular flow patterns and proximal aortic wall lesions in patients undergoing surgery for bicuspid aortic valve (BAV) stenosis. A total of 48 consecutive patients with BAV stenosis (mean age 58 ± 9 years, 65% male) underwent aortic valve replacement (AVR) ± proximal aortic surgery from January 2012 through February 2013. Preoperative cardiac phase-contrast cine magnetic resonance imaging (MRI) assessment was performed in all patients in order to detect the area of maximal flow-induced stress in the proximal aorta. Based on these MRI data, two aortic wall samples (i.e. area of the maximal stress (jet sample) and the opposite aortic wall (control sample)) were collected during AVR surgery. Aortic wall changes were graded based on a summation of seven histological criteria (each scored from 0 to 3). Histological sum score (0-21) was separately calculated and compared between the two aortic samples (i.e. jet sample vs control sample). An eccentric transvalvular flow jet hitting the proximal aortic wall could be identified in all 48 (100%) patients. The mean histological sum score was significantly higher in the jet sample vs control sample areas of the aorta (i.e. 4.1 ± 1.8 vs 2.2 ± 1.5, respectively) (P = 0.02). None of the patients had a higher sum score value in the control sample. Our study demonstrates a strong correlation between the systolic pattern of the transvalvular flow jet and asymmetric proximal aortic wall changes in patients undergoing AVR for BAV stenosis. © The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  3. Erosion simulation of first wall beryllium armour under ITER transient heat loads

    NASA Astrophysics Data System (ADS)

    Bazylev, B.; Janeschitz, G.; Landman, I.; Pestchanyi, S.; Loarte, A.

    2009-04-01

    The beryllium is foreseen as plasma facing armour for the first wall in the ITER in form of Be-clad blanket modules in macrobrush design with brush size about 8-10 cm. In ITER significant heat loads during transient events (TE) are expected at the main chamber wall that may leads to the essential damage of the Be armour. The main mechanisms of metallic target damage remain surface melting and melt motion erosion, which determines the lifetime of the plasma facing components. Melting thresholds and melt layer depth of the Be armour under transient loads are estimated for different temperatures of the bulk Be and different shapes of transient loads. The melt motion damages of Be macrobrush armour caused by the tangential friction force and the Lorentz force are analyzed for bulk Be and different sizes of Be-brushes. The damage of FW under radiative loads arising during mitigated disruptions is numerically simulated.

  4. Depinning transition of a domain wall in ferromagnetic films

    DOE PAGES

    Xi, Bin; Luo, Meng -Bo; Vinokur, Valerii M.; ...

    2015-09-14

    Here, we report first principle numerical study of domain wall (DW) depinning in two-dimensional magnetic film, which is modeled by 2D random-field Ising system with the dipole-dipole interaction. We observe non-conventional activation-type motion of DW and reveal the fractal structure of DW near the depinning transition. We determine scaling functions describing critical dynamics near the transition and obtain universal exponents establishing connection between thermal softening of pinning potential and critical dynamics. In addition, we observe that tuning the strength of the dipole-dipole interaction switches DW dynamics between two different universality classes, corresponding to two distinct dynamic regimes characterized by non-Arrheniusmore » and conventional Arrhenius-type DW motions.« less

  5. Biased Brownian motion in narrow channels with asymmetry and anisotropy

    NASA Astrophysics Data System (ADS)

    To, Kiwing; Peng, Zheng

    2016-11-01

    We study Brownian motion of a single millimeter size bead confined in a quasi-two-dimensional horizontal channel with built-in anisotropy and asymmetry. Channel asymmetry is implemented by ratchet walls while anisotropy is introduced using a channel base that is grooved along the channel axis so that a bead can acquire a horizontal impulse perpendicular to the longitudinal direction when it collides with the base. When energy is injected to the channel by vertical vibration, the combination of asymmetric walls and anisotropic base induces an effective force which drives the bead into biased diffusive motion along the channel axis with diffusivity and drift velocity increase with vibration strength. The magnitude of this driving force, which can be measured in experiments of tilted channel, is found to be consistent to those obtained from dynamic mobility and position probability distribution measurements. These results are explained by a simple collision model that suggests the random kinetic energies transfer between different translational degrees of freedom may be turned into useful work in the presence of asymmetry and anisotropy.

  6. Biased Brownian motion in narrow channels with asymmetry and anisotropy

    NASA Astrophysics Data System (ADS)

    Peng, Zheng; To, Kiwing

    2016-08-01

    We study Brownian motion of a single millimeter size bead confined in a quasi-two-dimensional horizontal channel with built-in anisotropy and asymmetry. Channel asymmetry is implemented by ratchet walls while anisotropy is introduced using a channel base that is grooved along the channel axis so that a bead can acquire a horizontal impulse perpendicular to the longitudinal direction when it collides with the base. When energy is injected to the channel by vertical vibration, the combination of asymmetric walls and anisotropic base induces an effective force which drives the bead into biased diffusive motion along the channel axis with diffusivity and drift velocity increase with vibration strength. The magnitude of this driving force, which can be measured in experiments on a tilted channel, is found to be consistent with those obtained from dynamic mobility and position probability distribution measurements. These results are explained by a simple collision model that suggests the random kinetic energy transfer between different translational degrees of freedom may be turned into useful work in the presence of asymmetry and anisotropy.

  7. Universal current-velocity relation of skyrmion motion in chiral magnets

    NASA Astrophysics Data System (ADS)

    Iwasaki, Junichi; Mochizuki, Masahito; Nagaosa, Naoto

    2013-03-01

    Current-driven motion of the magnetic domain wall requires large critical current density jc ~109 -1012 A/m2, at which the joule heating is a serious problem. The skyrmions recently discovered in chiral magnets, on the other hand, have much smaller critical current of jc ~105 -106 A/m2. We present a numerical simulation of the Landau-Lifshitz-Gilbert equation, which reveals a remarkably robust and universal current-velocity relation of the slyrmion motion driven by the spin transfer torque unaffected by either impurities or nonadiabatic effect in sharp contrast to the case of domain wall or spin helix (HL). Simulation results are analyzed using a theory based on Thiele's equation, and it is concluded that this surprising behavior is due to the Magnus force and flexible shape-deformation of individual skyrmions and skyrmion crystal (SkX), which enable them to avoid pinning centers and then weaken the net pinning force. Dynamical deformation of SkX leads to the fluctuation of Bragg peak with large amplitude, which can be detected by the recent neutron-scattering experiment.

  8. Strain induced parametric pumping of a domain wall and its depinning from a notch

    NASA Astrophysics Data System (ADS)

    Nepal, Rabindra; Gungordu, Utkan; Kovalev, Alexey

    Using Thiele's method and detailed micromagnetic simulations, we study resonant oscillation of a domain wall in a notch of a ferromagnetic nanowire due to the modulation of magnetic anisotropy by external AC strain. Such resonant oscillation results from the parametric pumping of domain wall by AC strain at frequency about double the free domain wall oscillation frequency, which is mainly determined by the perpendicular anisotropy and notch geometry. This effect leads to a substantial reduction in depinning field or current required to depin a domain wall from the notch, and offers a mechanism for efficient domain wall motion in a notched nanowire. Our theoretical model accounts for the pinning potential due to a notch by explicitly calculating ferromagnetic energy as a function of notch geometry parameters. We also find similar resonant domain wall oscillations and reduction in the domain wall depinning field or current due to surface acoustic wave in soft ferromagnetic nanowire without uniaxial anisotropy that energetically favors an in-plane domain wall. DOE Early Career Award DE-SC0014189 and DMR- 1420645.

  9. Self-similarity in the inertial region of wall turbulence.

    PubMed

    Klewicki, J; Philip, J; Marusic, I; Chauhan, K; Morrill-Winter, C

    2014-12-01

    The inverse of the von Kármán constant κ is the leading coefficient in the equation describing the logarithmic mean velocity profile in wall bounded turbulent flows. Klewicki [J. Fluid Mech. 718, 596 (2013)] connects the asymptotic value of κ with an emerging condition of dynamic self-similarity on an interior inertial domain that contains a geometrically self-similar hierarchy of scaling layers. A number of properties associated with the asymptotic value of κ are revealed. This is accomplished using a framework that retains connection to invariance properties admitted by the mean statement of dynamics. The development leads toward, but terminates short of, analytically determining a value for κ. It is shown that if adjacent layers on the hierarchy (or their adjacent positions) adhere to the same self-similarity that is analytically shown to exist between any given layer and its position, then κ≡Φ(-2)=0.381966..., where Φ=(1+√5)/2 is the golden ratio. A number of measures, derived specifically from an analysis of the mean momentum equation, are subsequently used to empirically explore the veracity and implications of κ=Φ(-2). Consistent with the differential transformations underlying an invariant form admitted by the governing mean equation, it is demonstrated that the value of κ arises from two geometric features associated with the inertial turbulent motions responsible for momentum transport. One nominally pertains to the shape of the relevant motions as quantified by their area coverage in any given wall-parallel plane, and the other pertains to the changing size of these motions in the wall-normal direction. In accord with self-similar mean dynamics, these two features remain invariant across the inertial domain. Data from direct numerical simulations and higher Reynolds number experiments are presented and discussed relative to the self-similar geometric structure indicated by the analysis, and in particular the special form of self

  10. A near-wall two-equation model for compressible turbulent flows

    NASA Technical Reports Server (NTRS)

    Zhang, H. S.; So, R. M. C.; Speziale, C. G.; Lai, Y. G.

    1991-01-01

    A near-wall two-equation turbulence model of the K - epsilon type is developed for the description of high-speed compressible flows. The Favre-averaged equations of motion are solved in conjunction with modeled transport equations for the turbulent kinetic energy and solenoidal dissipation wherein a variable density extension of the asymptotically consistent near-wall model of So and co-workers is supplemented with new dilatational models. The resulting compressible two-equation model is tested in the supersonic flat plate boundary layer - with an adiabatic wall and with wall cooling - for Mach numbers as large as 10. Direct comparisons of the predictions of the new model with raw experimental data and with results from the K - omega model indicate that it performs well for a wide range of Mach numbers. The surprising finding is that the Morkovin hypothesis, where turbulent dilatational terms are neglected, works well at high Mach numbers, provided that the near wall model is asymptotically consistent. Instances where the model predictions deviate from the experiments appear to be attributable to the assumption of constant turbulent Prandtl number - a deficiency that will be addressed in a future paper.

  11. Streak instability as an initiating mechanism of the large-scale motions in a turbulent channel flow

    NASA Astrophysics Data System (ADS)

    de Giovanetti, Matteo; Sung, Hyung Jin; Hwang, Yongyun

    2016-11-01

    The large-scale motions (or bulges) have often been believed to be formed via merge and/or growth of the near-wall hairpin vortical structures. Here, we report our observation that they can be directly generated by an instability of the amplified streaky motions in the outer region (i.e. very-large-scale motions) through the self-sustaining process. We design a LES-based numerical experiment in turbulent channel flow for Reτ = 2000 where a body forcing is implemented to artificially drive an infinitely long streaky motion in the outer layer. As the forcing amplitude is increased, it is found that a new energetic structure emerges at λx 3 4 h of the streamwise length (h is the half height of channel) particularly in the wall-normal and spanwise velocities. A careful statistical examination reveals that this structure is likely to be linked with the sinuous-mode streak instability of the amplified streak, consistent with previous theoretical studies. Application of dynamic mode decomposition to this instability further shows that the phase speed of this structure scales with the outer velocity and it is initiated around the critical layer of the streaky flow.

  12. Transmission of wave energy in curved ducts. [acoustic propagation within rigid walls

    NASA Technical Reports Server (NTRS)

    Rostafinski, W.

    1974-01-01

    Investigation of the ability of circular bends to transmit acoustic energy flux. A formulation of wave-energy flow is developed for motion in curved ducts. A parametric study over a range of frequencies shows the ability of circular bends to transmit energy in the case of perfectly rigid walls.

  13. Influence of angiographic collateral circulation on myocardial perfusion in patients with chronic total occlusion of a single coronary artery and no prior myocardial infarction.

    PubMed

    Aboul-Enein, Fatma; Kar, Saibal; Hayes, Sean W; Sciammarella, Maria; Abidov, Aiden; Makkar, Raj; Friedman, John D; Eigler, Neal; Berman, Daniel S

    2004-06-01

    The functional role of various angiographic grades for coronary collaterals remains controversial. The aim of this study was to assess the influence of the Rentrop angiographic grading of coronary collaterals on myocardial perfusion in patients with single-vessel chronic total occlusion (CTO) and no prior myocardial infarction (MI). The study included 56 patients with single-vessel CTO and no prior MI who underwent rest-stress myocardial perfusion SPECT and coronary angiography within 6 mo. All patients had angiographic evidence of coronary collaterals. Patients were divided according to the Rentrop classification: Group I had grade 1 or 2 (n = 25) and group II had grade 3 collaterals (n = 31). Group I had a higher frequency of resting regional wall motion abnormalities on left ventriculography (52.6% vs. 19.2% [P = 0.019]). The mean perfusion scores of the overall population showed severe and extensive stress perfusion defects (summed stress score of 14.1 +/- 7.1 and summed difference score of 12.9 +/- 6.9) but minimal resting perfusion defects (summed rest score of 1.0 +/- 2.7). No perfusion scores differed between the 2 groups. The perfusion findings suggested that chronic stunning rather than hibernation is the principal cause of regional wall motion abnormalities in these patients. In the setting of single-vessel CTO and no prior MI, coronary collaterals appear to protect against resting perfusion defects. Excellent angiographic collaterals may prevent resting regional wall motion abnormalities but do not appear to protect against stress-induced perfusion defects.

  14. Cell adhesion during bullet motion in capillaries.

    PubMed

    Takeishi, Naoki; Imai, Yohsuke; Ishida, Shunichi; Omori, Toshihiro; Kamm, Roger D; Ishikawa, Takuji

    2016-08-01

    A numerical analysis is presented of cell adhesion in capillaries whose diameter is comparable to or smaller than that of the cell. In contrast to a large number of previous efforts on leukocyte and tumor cell rolling, much is still unknown about cell motion in capillaries. The solid and fluid mechanics of a cell in flow was coupled with a slip bond model of ligand-receptor interactions. When the size of a capillary was reduced, the cell always transitioned to "bullet-like" motion, with a consequent decrease in the velocity of the cell. A state diagram was obtained for various values of capillary diameter and receptor density. We found that bullet motion enables firm adhesion of a cell to the capillary wall even for a weak ligand-receptor binding. We also quantified effects of various parameters, including the dissociation rate constant, the spring constant, and the reactive compliance on the characteristics of cell motion. Our results suggest that even under the interaction between P-selectin glycoprotein ligand-1 (PSGL-1) and P-selectin, which is mainly responsible for leukocyte rolling, a cell is able to show firm adhesion in a small capillary. These findings may help in understanding such phenomena as leukocyte plugging and cancer metastasis. Copyright © 2016 the American Physiological Society.

  15. Rotational Response of Toe-Restrained Retaining Walls to Earthquake Ground Motions

    DTIC Science & Technology

    2006-12-01

    v CG I CG θ In fo rm at io n T ec h n ol og y La b or at or y Approved for public release; distribution is unlimited. Infrastructure...the Internet . The major disadvantage of FLUSH is that it does not allow for permanent displacement of the wall (although strain softening associated...and ( )2 tan sin cosA Su u uCONSTANT S L S Lα α− α= + • • • + • • A.30 The dynamic active earth pressure force, PAE, is equal to the maximum value

  16. Guidance of microswimmers by wall and flow: Thigmotaxis and rheotaxis of unsteady squirmers in two and three dimensions

    NASA Astrophysics Data System (ADS)

    Ishimoto, Kenta

    2017-10-01

    The motions of an unsteady circular-disk squirmer and a spherical squirmer have been investigated in the presence of a no-slip infinite wall and a background shear flow in order to clarify the similarities and differences between two- and three-dimensional motions. Despite the similar bifurcation structure of the dynamical system, the stability of the fixed points differs due to the Hamiltonian structure of the disk squirmer. Once the unsteady oscillating surface velocity profile is considered, the disk squirmer can behave in a chaotic manner and cease to be confined in a near-wall region. In contrast, in an unsteady spherical squirmer, the dynamics is well attracted by a stable fixed point. Additional wall contact interactions lead to stable fixed points for the disk squirmer, and, in turn, the surface entrapment of the disk squirmer can be stabilized, regardless of the existence of the background flow. Finally, we consider spherical motion under a background flow. The separated time scales of the surface entrapment (thigmotaxis) and the turning toward the flow direction (rheotaxis) enable us to reduce the dynamics to two-dimensional phase space, and simple weather-vane mechanics can predict squirmer rheotaxis. The analogous structure of the phase plane with the wall contact in two and three dimensions implies that the two-dimensional disk swimmer successfully captures the nonlinear interactions, and thus two-dimensional approximation could be useful in designing microfluidic devices for the guidance of microswimmers and for clarifying the locomotions in a complex geometry.

  17. Hydroxyl Tagging Velocimetry in a Mach 2 Flow With a Wall Cavity (Postprint)

    DTIC Science & Technology

    2005-01-01

    tagging velocimetry (HTV) measurements of velocity were made in a Mach 2 flow with a wall cavity. In the HTV method, ArF excimer laser (193 nm) beams...is tracked by planar laser -induced fluorescence. The grid motion over a fixed time delay yields about 50 velocity vectors of the two-dimensional flow...Mach 2 flow with a wall cavity. In the HTV method, ArF excimer laser (193 nm) beams pass through a humid gas and dissociate H2O into H + OH to form

  18. Processive movement of MreB-associated cell wall biosynthetic complexes in bacteria.

    PubMed

    Domínguez-Escobar, Julia; Chastanet, Arnaud; Crevenna, Alvaro H; Fromion, Vincent; Wedlich-Söldner, Roland; Carballido-López, Rut

    2011-07-08

    The peptidoglycan cell wall and the actin-like MreB cytoskeleton are major determinants of cell shape in rod-shaped bacteria. The prevailing model postulates that helical, membrane-associated MreB filaments organize elongation-specific peptidoglycan-synthesizing complexes along sidewalls. We used total internal reflection fluorescence microscopy to visualize the dynamic relation between MreB isoforms and cell wall synthesis in live Bacillus subtilis cells. During exponential growth, MreB proteins did not form helical structures. Instead, together with other morphogenetic factors, they assembled into discrete patches that moved processively along peripheral tracks perpendicular to the cell axis. Patch motility was largely powered by cell wall synthesis, and MreB polymers restricted diffusion of patch components in the membrane and oriented patch motion.

  19. Oil Motion Control by an Extra Pinning Structure in Electro-Fluidic Display.

    PubMed

    Dou, Yingying; Tang, Biao; Groenewold, Jan; Li, Fahong; Yue, Qiao; Zhou, Rui; Li, Hui; Shui, Lingling; Henzen, Alex; Zhou, Guofu

    2018-04-06

    Oil motion control is the key for the optical performance of electro-fluidic displays (EFD). In this paper, we introduced an extra pinning structure (EPS) into the EFD pixel to control the oil motion inside for the first time. The pinning structure canbe fabricated together with the pixel wall by a one-step lithography process. The effect of the relative location of the EPS in pixels on the oil motion was studied by a series of optoelectronic measurements. EPS showed good control of oil rupture position. The properly located EPS effectively guided the oil contraction direction, significantly accelerated switching on process, and suppressed oil overflow, without declining in aperture ratio. An asymmetrically designed EPS off the diagonal is recommended. This study provides a novel and facile way for oil motion control within an EFD pixel in both direction and timescale.

  20. Controlling depinning and propagation of single domain-walls in magnetic microwires

    NASA Astrophysics Data System (ADS)

    Jiménez, Alejandro; del Real, Rafael P.; Vázquez, Manuel

    2013-03-01

    The magnetization reversal in magnetostrictive amorphous microwires takes place by depinning and propagation of a single domain wall. This is a consequence of the particular domain structure determined by the strong uniaxial anisotropy from the reinforcement of magnetoelastic and shape contributions. In the present study, after an overview on the current state-of-the art on the topic, we introduce the general behaviour of single walls in 30 to 40 cm long Fe-base microwires propagating under homogeneous field. Depending on the way the walls are generated, we distinguish among three different walls namely, standard wall, DWst, depinned and propagating from the wire's end under homogeneous field which motion is the first one to switch on; reverse wall, DWrev, propagating from the opposite end under non-homogeneous field, and defect wall, DWdef, nucleated around local defect. Both, DWrev and DWdef are observed only under large enough applied field. In the subsequent section, we study the propagation of a wall under applied field smaller than the switching field. There, we conclude that a minimum field, Hdep,0, is needed to depin the DWst, as well as that a minimum field, Hprop,0, is required for the wall to propagate long distances. In the last section, we analyse the shape of induced signals in the pickup coils upon the crossing of the walls and its correlation to the domain walls shape. We conclude that length and shape of the wall are significantly distorted by the fact that the wall is typically as long as the measuring coils. Contribution to the Topical Issue "New Trends in Magnetism and Magnetic Materials", edited by Francesca Casoli, Massimo Solzi and Paola Tiberto.

  1. The unidirectional motion of two heat-conducting liquids in a flat channel

    NASA Astrophysics Data System (ADS)

    Andreev, V. K.; Cheremnykh, E. N.

    2017-10-01

    The unidirectional motion of two viscous incompressible liquids in a flat channel is studied. Liquids contact on a flat interface. External boundaries are fixed solid walls, on which the non-stationary temperature gradients are given. The motion is induced by a joint action of thermogravitational and thermocapillary forces and given total non - stationary fluid flow rate in layers. The corresponding initial boundary value problem is conjugate and inverse because the pressure gradients along axes channel have to be determined together with the velocity and temperature field. For this problem the exact stationary solution is found and a priori estimates of non - stationary solutions are obtained. In Laplace images the solution of the non - stationary problem is found in quadratures. It is proved, that the solution converges to a steady regime with time, if the temperature on the walls and the fluid flow rate are stabilized. The numerical calculations for specific liquid media good agree with the theoretical results.

  2. Cardiac contraction motion compensation in gated myocardial perfusion SPECT: A comparative study.

    PubMed

    Salehi, Narges; Rahmim, Arman; Fatemizadeh, Emad; Akbarzadeh, Afshin; Farahani, Mohammad Hossein; Farzanefar, Saeed; Ay, Mohammad Reza

    2018-05-01

    Cardiac contraction significantly degrades quality and quantitative accuracy of gated myocardial perfusion SPECT (MPS) images. In this study, we aimed to explore different techniques in motion-compensated temporal processing of MPS images and their impact on image quality and quantitative accuracy. 50 patients without known heart condition underwent gated MPS. 3D motion compensation methods using Motion Freezing by Cedars Sinai (MF), Log-domain Diffeomorphic Demons (LDD) and Free-Form Deformation (FFD) were applied to warp all image phases to fit the end-diastolic (ED) phase. Afterwards, myocardial wall thickness, myocardial to blood pool contrast, and image contrast-to noise ratio (CNR) were measured in summed images with no motion compensation (NoMC) and compensated images (MF, LDD and FFD). Total Perfusion Defect (TPD) was derived from Cedars-Sinai software, on the basis of sex-specific normal limits. Left ventricle (LV) lateral wall thickness was reduced after applying motion compensation (p < 0.05). Myocardial to blood pool contrast and CNR in compensated images were greater than NoMC (p < 0.05). TPD_LDD was in good agreement with the corresponding TPD_MF (p = 0.13). All methods have improved image quality and quantitative performance relative to NoMC. LDD and FFD are fully automatic and do not require any manual intervention, while MF is dependent on contour definition. In terms of diagnostic parameters LDD is in good agreement with MF which is a clinically accepted method. Further investigation along with diagnostic reference standards, in order to specify diagnostic value of each technique is recommended. Copyright © 2018 Associazione Italiana di Fisica Medica. All rights reserved.

  3. Turbulence and secondary motions in square duct flow

    NASA Astrophysics Data System (ADS)

    Pirozzoli, Sergio; Modesti, Davide; Orlandi, Paolo; Grasso, Francesco

    2017-11-01

    We study turbulent flows in pressure-driven ducts with square cross-section through DNS up to Reτ 1050 . Numerical simulations are carried out over extremely long integration times to get adequate convergence of the flow statistics, and specifically high-fidelity representation of the secondary motions which arise. The intensity of the latter is found to be in the order of 1-2% of the bulk velocity, and unaffected by Reynolds number variations. The smallness of the mean convection terms in the streamwise vorticity equation points to a simple characterization of the secondary flows, which in the asymptotic high-Re regime are found to be approximated with good accuracy by eigenfunctions of the Laplace operator. Despite their effect of redistributing the wall shear stress along the duct perimeter, we find that secondary motions do not have large influence on the mean velocity field, which can be characterized with good accuracy as that resulting from the concurrent effect of four independent flat walls, each controlling a quarter of the flow domain. As a consequence, we find that parametrizations based on the hydraulic diameter concept, and modifications thereof, are successful in predicting the duct friction coefficient. This research was carried out using resources from PRACE EU Grants.

  4. Oswestry Disability Index is a better indicator of lumbar motion than the Visual Analogue Scale.

    PubMed

    Ruiz, Ferrin K; Bohl, Daniel D; Webb, Matthew L; Russo, Glenn S; Grauer, Jonathan N

    2014-09-01

    Lumbar pathology is often associated with axial pain or neurologic complaints. It is often presumed that such pain is associated with decreased lumbar motion; however, this correlation is not well established. The utility of various outcome measures that are used in both research and clinical practice have been studied, but the connection with range of motion (ROM) has not been well documented. The current study was performed to assess objectively the postulated correlation of lumbar complaints (based on standardized outcome measures) with extremes of lumbar ROM and functional ROM (fROM) with activities of daily living (ADLs) as assessed with an electrogoniometer. This study was a clinical cohort study. Subjects slated to undergo a lumbar intervention (injection, decompression, and/or fusion) were enrolled voluntarily in the study. The two outcome measures used in the study were the Visual Analogue Scale (VAS) for axial extremity, lower extremity, and combined axial and lower extremity, as well as the Oswestry Disability Index (ODI). Pain and disability scores were assessed with the VAS score and ODI. A previously validated electrogoniometer was used to measure ROM (extremes of motion in three planes) and fROM (functional motion during 15 simulated activities of daily living). Pain and disability scores were analyzed for statistically significant association with the motion assessments using linear regression analyses. Twenty-eight men and 39 women were enrolled, with an average age of 55.6 years (range, 18-79 years). The ODI and VAS were associated positively (p<.001). Combined axial and lower extremity VAS scores were associated with lateral and rotational ROM (p<.05), but not with flexion/extension or any fROM. Similar findings were noted for separately analyzed axial and lower extremity VAS scores. On the other hand, the ODI correlated inversely with ROM in all planes, and fROM in at least one plane for 10 of 15 ADLs (p<.05). Extremes of lumbar motion and

  5. 3D ground‐motion simulations of Mw 7 earthquakes on the Salt Lake City segment of the Wasatch fault zone: Variability of long‐period (T≥1  s) ground motions and sensitivity to kinematic rupture parameters

    USGS Publications Warehouse

    Moschetti, Morgan P.; Hartzell, Stephen; Ramirez-Guzman, Leonardo; Frankel, Arthur; Angster, Stephen J.; Stephenson, William J.

    2017-01-01

    We examine the variability of long‐period (T≥1  s) earthquake ground motions from 3D simulations of Mw 7 earthquakes on the Salt Lake City segment of the Wasatch fault zone, Utah, from a set of 96 rupture models with varying slip distributions, rupture speeds, slip velocities, and hypocenter locations. Earthquake ruptures were prescribed on a 3D fault representation that satisfies geologic constraints and maintained distinct strands for the Warm Springs and for the East Bench and Cottonwood faults. Response spectral accelerations (SA; 1.5–10 s; 5% damping) were measured, and average distance scaling was well fit by a simple functional form that depends on the near‐source intensity level SA0(T) and a corner distance Rc:SA(R,T)=SA0(T)(1+(R/Rc))−1. Period‐dependent hanging‐wall effects manifested and increased the ground motions by factors of about 2–3, though the effects appeared partially attributable to differences in shallow site response for sites on the hanging wall and footwall of the fault. Comparisons with modern ground‐motion prediction equations (GMPEs) found that the simulated ground motions were generally consistent, except within deep sedimentary basins, where simulated ground motions were greatly underpredicted. Ground‐motion variability exhibited strong lateral variations and, at some sites, exceeded the ground‐motion variability indicated by GMPEs. The effects on the ground motions of changing the values of the five kinematic rupture parameters can largely be explained by three predominant factors: distance to high‐slip subevents, dynamic stress drop, and changes in the contributions from directivity. These results emphasize the need for further characterization of the underlying distributions and covariances of the kinematic rupture parameters used in 3D ground‐motion simulations employed in probabilistic seismic‐hazard analyses.

  6. Current-driven second-harmonic domain wall resonance in ferromagnetic metal/nonmagnetic metal bilayers: A field-free method for spin Hall angle measurements

    NASA Astrophysics Data System (ADS)

    Hajiali, M. R.; Hamdi, M.; Roozmeh, S. E.; Mohseni, S. M.

    2017-10-01

    We study the ac current-driven domain wall motion in bilayer ferromagnetic metal (FM)/nonmagnetic metal (NM) nanowires. The solution of the modified Landau-Lifshitz-Gilbert equation including all the spin transfer torques is used to describe motion of the domain wall in the presence of the spin Hall effect. We show that the domain wall center has a second-harmonic frequency response in addition to the known first-harmonic excitation. In contrast to the experimentally observed second-harmonic response in harmonic Hall measurements of spin-orbit torque in magnetic thin films, this second-harmonic response directly originates from spin-orbit torque driven domain wall dynamics. Based on the spin current generated by domain wall dynamics, the longitudinal spin motive force generated voltage across the length of the nanowire is determined. The second-harmonic response introduces additionally a practical field-free and all-electrical method to probe the effective spin Hall angle for FM/NM bilayer structures that could be applied in experiments. Our results also demonstrate the capability of utilizing FM/NM bilayer structures in domain wall based spin-torque signal generators and resonators.

  7. Influence of strong perturbations on wall-bounded flows

    NASA Astrophysics Data System (ADS)

    Buxton, O. R. H.; Ewenz Rocher, M.; Rodríguez-López, E.

    2018-01-01

    Single-point hot-wire measurements are made downstream of a series of spanwise repeating obstacles that are used to generate an artificially thick turbulent boundary layer. The measurements are made in the near field, in which the turbulent boundary layer is beginning to develop from the wall-bounded wakes of the obstacles. The recent paper of Rodríguez-López et al. [E. Rodríguez-López et al., Phys. Rev. Fluids 1, 074401 (2016), 10.1103/PhysRevFluids.1.074401] broadly categorized the mechanisms by which canonical turbulent boundary layers eventually develop from wall-bounded wakes into two distinct mechanisms, the wall-driven and wake-driven mechanisms. In the present work we attempt to identify the geometric parameters of tripping arrays that trigger these two mechanisms by examining the spectra of the streamwise velocity fluctuations and the intermittent outer region of the flow. Using a definition reliant upon the magnitude of the velocity fluctuations, an intermittency function is devised that can discriminate between turbulent and nonturbulent flow. These results are presented along with the spectra in order to try to ascertain which aspects of a trip's geometry are more likely to favor the wall-driven or wake-driven mechanism. The geometrical aspects of the trips tested are the aspect ratio, the total blockage, and the blockage at the wall. The results indicate that the presence, or not, of perforations is the most significant factor in affecting the flow downstream. The bleed of fluid through the perforations reenergizes the mean recirculation and leads to a narrower intermittent region with a more regular turbulent-nonturbulent interface. The near-wall turbulent motions are found to recover quickly downstream of all of the trips with a wall blockage of 50%, but a clear influence of the outer fluctuations, generated by the tip vortices of the trips, is observed in the near-wall region for the high total blockage trips. The trip with 100% wall blockage is

  8. Deposition pattern and tracer particle motion of evaporating multi-component sessile droplets.

    PubMed

    Amjad, Muhammad; Yang, Yang; Raza, Ghulam; Gao, Hui; Zhang, Jun; Zhou, Leping; Du, Xiaoze; Wen, Dongsheng

    2017-11-15

    The understanding of near-wall motion, evaporation behavior and dry pattern of sessile nanofluid droplets is fundamental to a wide range of applications such as painting, spray drying, thin film coating, fuel injection and inkjet printing. However, a deep insight into the heat transfer, fluid flow, near-wall particle velocity and their effects on the resulting dry patterns is still much needed to take the full advantage of these nano-sized particles in the droplet. This work investigates the effect of direct absorptive silicon/silver (Si/Ag) hybrid nanofluids via two experiments. The first experiment identifies the motion of tracer particles near the triple line of a sessile nanofluid droplet on a super-hydrophilic substrate under ambient conditions by the multilayer nanoparticle image velocimetry (MnPIV) technique. The second experiment reveals the effect of light-sensitive Si/Ag composite nanoparticles on the droplet evaporation rate and subsequent drying patterns under different radiation intensities. The results show that the presence of nanoparticle in a very small proportion significantly affects the motion of tracer particles, leading to different drying patterns and evaporation rates, which can be very important for the applications such as spray coating and inkjet printing. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Effects of Incentive Spirometry on Respiratory Motion in Healthy Subjects Using Cine Breathing Magnetic Resonance Imaging

    PubMed Central

    Akazawa, Tsutomu; Sakuma, Tsuyoshi; Nagaya, Shigeyuki; Sonoda, Masaru; Tanaka, Yuji; Katogi, Takehide; Nemoto, Tetsuharu; Minami, Shohei

    2015-01-01

    Objective To investigate the effectiveness of incentive spirometry on respiratory motion in healthy subjects using cine breathing magnetic resonance imaging (MRI). Methods Ten non-smoking healthy subjects without any history of respiratory disease were studied. Subjects were asked to perform pulmonary training using incentive spirometry every day for two weeks. To assess the effectiveness of this training, pulmonary function tests and cine breathing MRI were performed before starting pulmonary training and two weeks after its completion. Results After training, there were significant improvements in vital capacity (VC) from 3.58±0.8 L to 3.74±0.8 L and in %VC from 107.4±10.8 to 112.1±8.2. Significant changes were observed in the right diaphragm motion, right chest wall motion, and left chest wall motion, which were increased from 55.7±9.6 mm to 63.4±10.2 mm, from 15.6±6.1 mm to 23.4±10.4 mm, and from 16.3±7.6 mm to 22.0±9.8 mm, respectively. Conclusion Two weeks of training using incentive spirometry provided improvements in pulmonary function and respiratory motion, which suggested that incentive spirometry may be a useful preoperative modality for improving pulmonary function during the perioperative period. PMID:26161341

  10. Elastohydrodynamics of a free cylinder near a soft wall

    NASA Astrophysics Data System (ADS)

    Mahadevan, L.; Salez, Thomas

    2015-11-01

    We consider the motion of a fluid-immersed negatively buoyant particle in the vicinity of a thin compressible elastic wall. We use scaling arguments to establish different regimes of settling, sliding, rolling and complement these estimates using thin-film lubrication dynamics to determine an asymptotic theory for the sedimentation, sliding, and spinning motions of a cylinder. Numerical integration of the resulting equations confirms our scaling relations and further yields a range of behaviours such as spontaneously oscillations when sliding, lift via a Magnus-like effect, a spin-induced reversal effect, and an unusual sedimentation singularity. Our description also allows us to address a sedimentation-sliding transition that can lead to the particle coasting over very long distances, similar to certain geophysical phenomena.

  11. Dislocation-mediated growth of bacterial cell walls

    PubMed Central

    Amir, Ariel; Nelson, David R.

    2012-01-01

    Recent experiments have illuminated a remarkable growth mechanism of rod-shaped bacteria: proteins associated with cell wall extension move at constant velocity in circles oriented approximately along the cell circumference [Garner EC, et al., (2011) Science 333:222–225], [Domínguez-Escobar J, et al. (2011) Science 333:225–228], [van Teeffelen S, et al. (2011) PNAS 108:15822–15827]. We view these as dislocations in the partially ordered peptidoglycan structure, activated by glycan strand extension machinery, and study theoretically the dynamics of these interacting defects on the surface of a cylinder. Generation and motion of these interacting defects lead to surprising effects arising from the cylindrical geometry, with important implications for growth. We also discuss how long range elastic interactions and turgor pressure affect the dynamics of the fraction of actively moving dislocations in the bacterial cell wall. PMID:22660931

  12. Autonomous Motion Learning for Intra-Vehicular Activity Space Robot

    NASA Astrophysics Data System (ADS)

    Watanabe, Yutaka; Yairi, Takehisa; Machida, Kazuo

    Space robots will be needed in the future space missions. So far, many types of space robots have been developed, but in particular, Intra-Vehicular Activity (IVA) space robots that support human activities should be developed to reduce human-risks in space. In this paper, we study the motion learning method of an IVA space robot with the multi-link mechanism. The advantage point is that this space robot moves using reaction force of the multi-link mechanism and contact forces from the wall as space walking of an astronaut, not to use a propulsion. The control approach is determined based on a reinforcement learning with the actor-critic algorithm. We demonstrate to clear effectiveness of this approach using a 5-link space robot model by simulation. First, we simulate that a space robot learn the motion control including contact phase in two dimensional case. Next, we simulate that a space robot learn the motion control changing base attitude in three dimensional case.

  13. Streaming and particle motion in acoustically-actuated leaky systems

    NASA Astrophysics Data System (ADS)

    Nama, Nitesh; Barnkob, Rune; Jun Huang, Tony; Kahler, Christian; Costanzo, Francesco

    2017-11-01

    The integration of acoustics with microfluidics has shown great promise for applications within biology, chemistry, and medicine. A commonly employed system to achieve this integration consists of a fluid-filled, polymer-walled microchannel that is acoustically actuated via standing surface acoustic waves. However, despite significant experimental advancements, the precise physical understanding of such systems remains a work in progress. In this work, we investigate the nature of acoustic fields that are setup inside the microchannel as well as the fundamental driving mechanism governing the fluid and particle motion in these systems. We provide an experimental benchmark using state-of-art 3D measurements of fluid and particle motion and present a Lagrangian velocity based temporal multiscale numerical framework to explain the experimental observations. Following verification and validation, we employ our numerical model to reveal the presence of a pseudo-standing acoustic wave that drives the acoustic streaming and particle motion in these systems.

  14. Elastohydrodynamic Lift at a Soft Wall

    NASA Astrophysics Data System (ADS)

    Davies, Heather S.; Débarre, Delphine; El Amri, Nouha; Verdier, Claude; Richter, Ralf P.; Bureau, Lionel

    2018-05-01

    We study experimentally the motion of nondeformable microbeads in a linear shear flow close to a wall bearing a thin and soft polymer layer. Combining microfluidics and 3D optical tracking, we demonstrate that the steady-state bead-to-surface distance increases with the flow strength. Moreover, such lift is shown to result from flow-induced deformations of the layer, in quantitative agreement with theoretical predictions from elastohydrodynamics. This study thus provides the first experimental evidence of "soft lubrication" at play at small scale, in a system relevant, for example, to the physics of blood microcirculation.

  15. Indoor imagery with a 3D through-wall synthetic aperture radar

    NASA Astrophysics Data System (ADS)

    Sévigny, Pascale; DiFilippo, David J.; Laneve, Tony; Fournier, Jonathan

    2012-06-01

    Through-wall radar imaging is an emerging technology with great interest to military and police forces operating in an urban environment. A through-wall imaging radar can potentially provide interior room layouts as well as detection and localization of targets of interest within a building. In this paper, we present our through-wall radar system mounted on the side of a vehicle and driven along a path in front of a building of interest. The vehicle is equipped with a LIDAR (Light Detection and Ranging) and motion sensors that provide auxiliary information. The radar uses an ultra wideband frequency-modulated continuous wave (FMCW) waveform to obtain high range resolution. Our system is composed of a vertical linear receive array to discriminate targets in elevation, and two transmit elements operated in a slow multiple-input multiple output (MIMO) configuration to increase the achievable elevation resolution. High resolution in the along-track direction is obtained through synthetic aperture radar (SAR) techniques. We present experimental results that demonstrate the 3-D capability of the radar. We further demonstrate target detection behind challenging walls, and imagery of internal wall features. Finally, we discuss future work.

  16. A law of the wall for turbulent boundary layers with suction: Stevenson's formula revisited

    NASA Astrophysics Data System (ADS)

    Vigdorovich, Igor

    2016-08-01

    The turbulent velocity field in the viscous sublayer of the boundary layer with suction to a first approximation is homogeneous in any direction parallel to the wall and is determined by only three constant quantities — the wall shear stress, the suction velocity, and the fluid viscosity. This means that there exists a finite algebraic relation between the turbulent shear stress and the longitudinal mean-velocity gradient, using which as a closure condition for the equations of motion, we establish an exact asymptotic behavior of the velocity profile at the outer edge of the viscous sublayer. The obtained relationship provides a generalization of the logarithmic law to the case of wall suction.

  17. Characterization of Severe Arterial Phase Respiratory Motion Artifact on Gadoxetate Disodium-Enhanced MRI - Assessment of Interrater Agreement and Reliability.

    PubMed

    Ringe, Kristina Imeen; Luetkens, Julian A; Fimmers, Rolf; Hammerstingl, Renate Maria; Layer, Günter; Maurer, Martin H; Nähle, Claas Philip; Michalik, Sabine; Reimer, Peter; Schraml, Christina; Schreyer, Andreas G; Stumpp, Patrick; Vogl, Thomas J; Wacker, Frank K; Willinek, Winfried; Kukuk, Guido Mattias

    2018-04-01

     To assess the interrater agreement and reliability of experienced abdominal radiologists in the characterization and grading of arterial phase gadoxetate disodium-related respiratory motion artifact on liver MRI.  This prospective multicenter study was initiated by the working group for abdominal imaging within the German Roentgen Society (DRG), and approved by the local IRB of each participating center. 11 board-certified radiologists independently reviewed 40 gadoxetate disodium-enhanced liver MRI datasets. Motion artifacts in the arterial phase were assessed on a 5-point scale. Interrater agreement and reliability were calculated using the intraclass correlation coefficient (ICC) and Kendall coefficient of concordance (W), with p < 0.05 deemed significant.  The ICC for interrater agreement and reliability were 0.983 (CI 0.973 - 0.990) and 0.985 (CI 0.978 - 0.991), respectively (both p < 0.0001), indicating excellent agreement and reliability. Kendall's W for interrater agreement was 0.865. A severe motion artifact, defined as a mean motion score ≥ 4 in the arterial phase was observed in 12 patients. In these specific cases, a motion score ≥ 4 was assigned by all readers in 75 % (n = 9/12 cases).  Differentiation and grading of arterial phase respiratory motion artifact is possible with a high level of inter-/intrarater agreement and interrater reliability, which is crucial for assessing the incidence of this phenomenon in larger multicenter studies.   · Inter- and intrarater agreement for motion artifact scoring is excellent among experienced readers.. · Interrater reliability for motion artifact scoring is excellent among experienced readers.. · Characterization of severe motion artifacts proved feasible in this multicenter study.. · Ringe KI, Luetkens JA, Fimmers R et al. Characterization of Severe Arterial Phase Respiratory Motion Artifact on Gadoxetate Disodium-Enhanced MRI - Assessment of Interrater Agreement

  18. The Versatile Elastohydrodynamics of a Free Particle near a Thin Soft Wall

    NASA Astrophysics Data System (ADS)

    Salez, Thomas; Saintyves, Baudouin; Mahadevan, L.

    2015-03-01

    We address the free motion of a buoyant particle inside a viscous fluid, in the vicinity of a thin compressible elastic wall. After discussing the main scalings, we obtain analytically the dominant drag forces within the soft lubrication approximation. By including those into the equations of motion of the particle, we establish a general governing system of three coupled nonlinear and singular differential equations, that describe the three essential motions: sedimentation, hydroplaning, and hydrospinning, through four dimensionless control parameters. Numerical integration allows us to predict a wide zoology of exotic solutions - despite the low-Reynolds feature of the flow - including: spontaneous oscillation, Magnus-like effect, enhanced sedimentation, and boomerang-like effect. We compare these predictions to experiments. The presented elementary approach could be of interest in the description of a broad variety of elastohydrodynamical phenomena, including: landslides, ageing of cartilaginous joints, and motion of a cell in a microfluidic channel or in a blood vessel.

  19. A synthetic GMPE based on deterministic simulated ground motion data obtained from dynamic rupture models

    NASA Astrophysics Data System (ADS)

    Dalguer, L. A.; Baumann, C.; Cauzzi, C.

    2013-12-01

    Empirical ground motion prediction in the very near-field and for large magnitudes is often based on extrapolation of ground motion prediction equations (GMPEs) outside the range where they are well constrained by recorded data. With empirical GMPEs it is also difficult to capture source-dominated ground motion patterns, such as the effects of velocity pulses induced by subshear and supershear rupture directivity, buried and surface-rupturing, hanging-wall and foot-wall, weak shallow layers, complex geometry faults and stress drop. A way to cope at least in part with these shortcomings is to augment the calibration datasets with synthetic ground motions. To this aim, physics-based dynamic rupture models - where the physical bases involved in the fault rupture are explicitly considered - appear to be a suitable approach to produce synthetic ground motions. In this contribution, we first perform an assessment of a database of synthetic ground motions generated by a suite of dynamic rupture simulations to verify compatibility of the peak ground amplitudes with current GMPEs. The synthetic data-set is composed by 360 earthquake scenarios with moment magnitudes in the range of 5.5-7, for three mechanisms of faulting (reverse, normal and strike-slip) and for both buried faults and surface rupturing faults. Second, we parameterise the synthetic dataset through a GMPE. For this purpose, we identify the basic functional forms by analyzing the variation of the synthetic peak ground motions and spectral ordinates as a function of different explanatory variables related to the earthquake source characteristics, in order to account for some of the source effects listed above. We argue that this study provides basic guidelines for the developments of future GMPEs including data from physics-based numerical simulations.

  20. Initial assessment of facial nerve paralysis based on motion analysis using an optical flow method.

    PubMed

    Samsudin, Wan Syahirah W; Sundaraj, Kenneth; Ahmad, Amirozi; Salleh, Hasriah

    2016-01-01

    An initial assessment method that can classify as well as categorize the severity of paralysis into one of six levels according to the House-Brackmann (HB) system based on facial landmarks motion using an Optical Flow (OF) algorithm is proposed. The desired landmarks were obtained from the video recordings of 5 normal and 3 Bell's Palsy subjects and tracked using the Kanade-Lucas-Tomasi (KLT) method. A new scoring system based on the motion analysis using area measurement is proposed. This scoring system uses the individual scores from the facial exercises and grades the paralysis based on the HB system. The proposed method has obtained promising results and may play a pivotal role towards improved rehabilitation programs for patients.

  1. Rocket-inspired tubular catalytic microjets with grating-structured walls as guiding empennages.

    PubMed

    Huang, Gaoshan; Wang, Jiyuan; Liu, Zhaoqian; Zhou, Dekai; Tian, Ziao; Xu, Borui; Li, Longqiu; Mei, Yongfeng

    2017-12-07

    Controllable locomotion in the micro-/nanoscale is challenging and attracts increasing research interest. Tubular microjets self-propelled by microbubbles are intensively investigated due to their high energy conversion efficiency, but the imperfection of the tubular geometry makes it harder to realize linear motion. Inspired by the macro rocket, we designed a tubular microjet with a grating-structured wall which mimics the guiding empennage of the macro rocket, and we found that the fluid can be effectively guided by the grooves. Both theoretical simulation and experimental work have been carried out, and the obtained results demonstrate that the stability margin of the grating-structured microjet can be enhanced. Compared with microjets with smooth walls, the structured microjets show an enhanced ability of moving linearly. In 10% H 2 O 2 , only 20% of the smooth microjets demonstrate linear trajectories, while 80% of the grating-structured microjets keep moving straight. The grating-structured microjet can maintain linear motion under external disturbance. We further propose to increase the stability by introducing a helical grating structure.

  2. Motion Versus Fixed Distraction of the Joint in the Treatment of Ankle Osteoarthritis

    PubMed Central

    Saltzman, Charles L.; Hillis, Stephen L.; Stolley, Mary P.; Anderson, Donald D.; Amendola, Annunziato

    2012-01-01

    Background: Initial reports have shown the efficacy of fixed distraction for the treatment of ankle osteoarthritis. We hypothesized that allowing ankle motion during distraction would result in significant improvements in outcomes compared with distraction without ankle motion. Methods: We conducted a prospective randomized controlled trial comparing the outcomes for patients with advanced ankle osteoarthritis who were managed with anterior osteophyte removal and either (1) fixed ankle distraction or (2) ankle distraction permitting joint motion. Thirty-six patients were randomized to treatment with either fixed distraction or distraction with motion. The patients were followed for twenty-four months after frame removal. The Ankle Osteoarthritis Scale (AOS) was the main outcome variable. Results: Two years after frame removal, subjects in both groups showed significant improvement compared with the status before treatment (p < 0.02 for both groups). The motion-distraction group had significantly better AOS scores than the fixed-distraction group at twenty-six, fifty-two, and 104 weeks after frame removal (p < 0.01 at each time point). At 104 weeks, the motion-distraction group had an overall mean improvement of 56.6% in the AOS score, whereas the fixed-distraction group had a mean improvement of 22.9% (p < 0.01). Conclusion: Distraction improved the patient-reported outcomes of treatment of ankle osteoarthritis. Adding ankle motion to distraction showed an early and sustained beneficial effect on outcome. Level of Evidence: Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence. PMID:22637202

  3. Accumulation of microswimmers near a surface mediated by collision and rotational Brownian motion.

    PubMed

    Li, Guanglai; Tang, Jay X

    2009-08-14

    In this Letter we propose a kinematic model to explain how collisions with a surface and rotational Brownian motion give rise to accumulation of microswimmers near a surface. In this model, an elongated microswimmer invariably travels parallel to the surface after hitting it from an oblique angle. It then swims away from the surface, facilitated by rotational Brownian motion. Simulations based on this model reproduce the density distributions measured for the small bacteria E. coli and Caulobacter crescentus, as well as for the much larger bull spermatozoa swimming between two walls.

  4. Electric-field control of magnetic domain-wall velocity in ultrathin cobalt with perpendicular magnetization.

    PubMed

    Chiba, D; Kawaguchi, M; Fukami, S; Ishiwata, N; Shimamura, K; Kobayashi, K; Ono, T

    2012-06-06

    Controlling the displacement of a magnetic domain wall is potentially useful for information processing in magnetic non-volatile memories and logic devices. A magnetic domain wall can be moved by applying an external magnetic field and/or electric current, and its velocity depends on their magnitudes. Here we show that the applying an electric field can change the velocity of a magnetic domain wall significantly. A field-effect device, consisting of a top-gate electrode, a dielectric insulator layer, and a wire-shaped ferromagnetic Co/Pt thin layer with perpendicular anisotropy, was used to observe it in a finite magnetic field. We found that the application of the electric fields in the range of ± 2-3 MV cm(-1) can change the magnetic domain wall velocity in its creep regime (10(6)-10(3) m s(-1)) by more than an order of magnitude. This significant change is due to electrical modulation of the energy barrier for the magnetic domain wall motion.

  5. Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR

    NASA Astrophysics Data System (ADS)

    Petibon, Yoann; Guehl, Nicolas J.; Reese, Timothy G.; Ebrahimi, Behzad; Normandin, Marc D.; Shoup, Timothy M.; Alpert, Nathaniel M.; El Fakhri, Georges; Ouyang, Jinsong

    2017-01-01

    PET is an established modality for myocardial perfusion imaging (MPI) which enables quantification of absolute myocardial blood flow (MBF) using dynamic imaging and kinetic modeling. However, heart motion and partial volume effects (PVE) significantly limit the spatial resolution and quantitative accuracy of PET MPI. Simultaneous PET-MR offers a solution to the motion problem in PET by enabling MR-based motion correction of PET data. The aim of this study was to develop a motion and PVE correction methodology for PET MPI using simultaneous PET-MR, and to assess its impact on both static and dynamic PET MPI using 18F-Flurpiridaz, a novel 18F-labeled perfusion tracer. Two dynamic 18F-Flurpiridaz MPI scans were performed on healthy pigs using a PET-MR scanner. Cardiac motion was tracked using a dedicated tagged-MRI (tMR) sequence. Motion fields were estimated using non-rigid registration of tMR images and used to calculate motion-dependent attenuation maps. Motion correction of PET data was achieved by incorporating tMR-based motion fields and motion-dependent attenuation coefficients into image reconstruction. Dynamic and static PET datasets were created for each scan. Each dataset was reconstructed as (i) Ungated, (ii) Gated (end-diastolic phase), and (iii) Motion-Corrected (MoCo), each without and with point spread function (PSF) modeling for PVE correction. Myocardium-to-blood concentration ratios (MBR) and apparent wall thickness were calculated to assess image quality for static MPI. For dynamic MPI, segment- and voxel-wise MBF values were estimated by non-linear fitting of a 2-tissue compartment model to tissue time-activity-curves. MoCo and Gating respectively decreased mean apparent wall thickness by 15.1% and 14.4% and increased MBR by 20.3% and 13.6% compared to Ungated images (P  <  0.01). Combined motion and PSF correction (MoCo-PSF) yielded 30.9% (15.7%) lower wall thickness and 82.2% (20.5%) higher MBR compared to Ungated data reconstructed

  6. Evolution and dynamics of shear-layer structures in near-wall turbulence

    NASA Technical Reports Server (NTRS)

    Johansson, Arne V.; Alfredsson, P. H.; Kim, John

    1991-01-01

    Near-wall flow structures in turbulent shear flows are analyzed, with particular emphasis on the study of their space-time evolution and connection to turbulence production. The results are obtained from investigation of a database generated from direct numerical simulation of turbulent channel flow at a Reynolds number of 180 based on half-channel width and friction velocity. New light is shed on problems associated with conditional sampling techniques, together with methods to improve these techniques, for use both in physical and numerical experiments. The results clearly indicate that earlier conceptual models of the processes associated with near-wall turbulence production, based on flow visualization and probe measurements need to be modified. For instance, the development of asymmetry in the spanwise direction seems to be an important element in the evolution of near-wall structures in general, and for shear layers in particular. The inhibition of spanwise motion of the near-wall streaky pattern may be the primary reason for the ability of small longitudinal riblets to reduce turbulent skin friction below the value for a flat surface.

  7. Statistical evidence of anasymptotic geometric structure to the momentum transporting motions in turbulent boundary layers

    NASA Astrophysics Data System (ADS)

    Morrill-Winter, Caleb; Philip, Jimmy; Klewicki, Joseph

    2017-03-01

    The turbulence contribution to the mean flow is reflected by the motions producing the Reynolds shear stress (<-uv>) and its gradient. Recent analyses of the mean dynamical equation, along with data, evidence that these motions asymptotically exhibit self-similar geometric properties. This study discerns additional properties associated with the uv signal, with an emphasis on the magnitudes and length scales of its negative contributions. The signals analysed derive from high-resolution multi-wire hot-wire sensor data acquired in flat-plate turbulent boundary layers. Space-filling properties of the present signals are shown to reinforce previous observations, while the skewness of uv suggests a connection between the size and magnitude of the negative excursions on the inertial domain. Here, the size and length scales of the negative uv motions are shown to increase with distance from the wall, whereas their occurrences decrease. A joint analysis of the signal magnitudes and their corresponding lengths reveals that the length scales that contribute most to <-uv> are distinctly larger than the average geometric size of the negative uv motions. Co-spectra of the streamwise and wall-normal velocities, however, are shown to exhibit invariance across the inertial region when their wavelengths are normalized by the width distribution, W(y), of the scaling layer hierarchy, which renders the mean momentum equation invariant on the inertial domain.

  8. Enhanced spin transfer torque effect for transverse domain walls in cylindrical nanowires

    NASA Astrophysics Data System (ADS)

    Franchin, Matteo; Knittel, Andreas; Albert, Maximilian; Chernyshenko, Dmitri S.; Fischbacher, Thomas; Prabhakar, Anil; Fangohr, Hans

    2011-09-01

    Recent studies have predicted extraordinary properties for transverse domain walls in cylindrical nanowires: zero depinning current, the absence of the Walker breakdown, and applications as domain wall oscillators. In order to reliably control the domain wall motion, it is important to understand how they interact with pinning centers, which may be engineered, for example, through modulations in the nanowire geometry (such as notches or extrusions) or in the magnetic properties of the material. In this paper we study the motion and depinning of transverse domain walls through pinning centers in ferromagnetic cylindrical nanowires. We use (i) magnetic fields and (ii) spin-polarized currents to drive the domain walls along the wire. The pinning centers are modelled as a section of the nanowire which exhibits a uniaxial crystal anisotropy where the anisotropy easy axis and the wire axis enclose a variable angle θP. Using (i) magnetic fields, we find that the minimum and the maximum fields required to push the domain wall through the pinning center differ by 30%. On the contrary, using (ii) spin-polarized currents, we find variations of a factor 130 between the minimum value of the depinning current density (observed for θP=0∘, i.e., anisotropy axis pointing parallel to the wire axis) and the maximum value (for θP=90∘, i.e., anisotropy axis perpendicular to the wire axis). We study the depinning current density as a function of the height of the energy barrier of the pinning center using numerical and analytical methods. We find that for an industry standard energy barrier of 40kBT, a depinning current of about 5μA (corresponding to a current density of 6×1010A/m2 in a nanowire of 10nm diameter) is sufficient to depin the domain wall. We reveal and explain the mechanism that leads to these unusually low depinning currents. One requirement for this depinning mechanism is for the domain wall to be able to rotate around its own axis. With the right barrier design

  9. Multi-Sensor Methods for Mobile Radar Motion Capture and Compensation

    NASA Astrophysics Data System (ADS)

    Nakata, Robert

    Remote sensing has many applications, including surveying and mapping, geophysics exploration, military surveillance, search and rescue and counter-terrorism operations. Remote sensor systems typically use visible image, infrared or radar sensors. Camera based image sensors can provide high spatial resolution but are limited to line-of-sight capture during daylight. Infrared sensors have lower resolution but can operate during darkness. Radar sensors can provide high resolution motion measurements, even when obscured by weather, clouds and smoke and can penetrate walls and collapsed structures constructed with non-metallic materials up to 1 m to 2 m in depth depending on the wavelength and transmitter power level. However, any platform motion will degrade the target signal of interest. In this dissertation, we investigate alternative methodologies to capture platform motion, including a Body Area Network (BAN) that doesn't require external fixed location sensors, allowing full mobility of the user. We also investigated platform stabilization and motion compensation techniques to reduce and remove the signal distortion introduced by the platform motion. We evaluated secondary ultrasonic and radar sensors to stabilize the platform resulting in an average 5 dB of Signal to Interference Ratio (SIR) improvement. We also implemented a Digital Signal Processing (DSP) motion compensation algorithm that improved the SIR by 18 dB on average. These techniques could be deployed on a quadcopter platform and enable the detection of respiratory motion using an onboard radar sensor.

  10. Fault Structural Control on Earthquake Strong Ground Motions: The 2008 Wenchuan Earthquake as an Example

    NASA Astrophysics Data System (ADS)

    Zhang, Yan; Zhang, Dongli; Li, Xiaojun; Huang, Bei; Zheng, Wenjun; Wang, Yuejun

    2018-02-01

    Continental thrust faulting earthquakes pose severe threats to megacities across the world. Recent events show the possible control of fault structures on strong ground motions. The seismogenic structure of the 2008 Wenchuan earthquake is associated with high-angle listric reverse fault zones. Its peak ground accelerations (PGAs) show a prominent feature of fault zone amplification: the values within the 30- to 40-km-wide fault zone block are significantly larger than those on both the hanging wall and the footwall. The PGA values attenuate asymmetrically: they decay much more rapidly in the footwall than in the hanging wall. The hanging wall effects can be seen on both the vertical and horizontal components of the PGAs, with the former significantly more prominent than the latter. All these characteristics can be adequately interpreted by upward extrusion of the high-angle listric reverse fault zone block. Through comparison with a low-angle planar thrust fault associated with the 1999 Chi-Chi earthquake, we conclude that different fault structures might have controlled different patterns of strong ground motion, which should be taken into account in seismic design and construction.

  11. Time-dependent bubble motion through a liquid filled compliant channel

    NASA Astrophysics Data System (ADS)

    Halpern, David; Gaver, Donald; Jensen, Oliver

    2000-11-01

    Pulmonary airway closure occurs when the liquid lining layer occludes the airway and obstructs airflow. Meniscus formation is the result of a surface-tension driven instability within the liquid layer. Airway 'compliant collapse' may result, which leads to tube buckling with airway walls held in apposition. Airway closure is common in premature neonates who do not produce sufficient surfactant and those suffering from emphysema. To model the reopening of a collapsed airway flooded with fluid, we consider the time-dependent motion of an air-bubble driven by a positive bubble pressure Pb through a liquid filled compliant channel. The governing Stokes equations are solved using the boundary element method near the bubble tip, and lubrication theory sufficiently far ahead of the buble where the channel walls have a gentle taper. Results show that for Pb > P_crit, the bubble moves forward and converges to a steady velocity as the airway walls 'peel' open. For Pb < P_crit, no steady solutions are found because fluid continuously accummulates ahead of the bubble tip. This result validates the stability analysis of the previously steady wall peeling solution branch. The impact of the flow field on transport of surfactant and the applied shear and normal stresses on the wall as they relate to pulmonary reopening are also discussed.

  12. Teaching Introductory Mineralogy With the GeoWall

    NASA Astrophysics Data System (ADS)

    Anderson, C. D.; Haymon, R. M.

    2003-12-01

    Mineralogy, like many topics in Earth Sciences, contains inherently three-dimensional topics that are difficult to teach. Concepts such as crystal symmetry and forms, Miller indices, the polymerization of silica tetrahedra and resulting structures of silicate mineral groups, and the interaction of light and minerals are particularly difficult. Two-dimensional diagrams are limited in their effectiveness, and physical models, while effective, are expensive and do not work as well in large class settings. The GeoWall system brings the effectiveness of physical models to the large classroom. In Fall 2003, we will integrate the GeoWall into our introductory mineralogy classes at UCSB using a combination of commercial software, atomic structure models available on the web, and custom content created in-house. The commercial software SHAPE (www.shapesoftware.com) allows users to build and display crystal shapes and their symmetry. Though not designed for the GeoWall, the software's stereopair display mode works perfectly on the system. Using the Chime web browser plug-in (www.mdl.com), computer models of silicate minerals available from the Virtual Museum of Minerals and Molecules (www.soils.umn.eduvirtual_museum) provide an interactive display of silicate mineral structure that illustrates the tetrahedral framework. Again, while not developed for the GeoWall, the Chime plug-in works seamlessly with the GeoWall hardware. 3-D GeoWall images that display light paths through minerals, and reveal relationships between crystal symmetry and optical indicatrix properties, have been developed in-house using a combination of SHAPE and 3D modeling software. The 3-D GeoWall images should convey in an instant these difficult concepts that students historically have struggled to visualize. Initial assessment of the GeoWall's effectiveness as a mineralogy teaching aid at UCSB in Fall 2003 will come from the instructor's impressions and by comparing test scores with classes from

  13. Particle Trajectories in Rotating Wall Cell Culture Devices

    NASA Technical Reports Server (NTRS)

    Ramachandran N.; Downey, J. P.

    1999-01-01

    Cell cultures are extremely important to the medical community since such cultures provide an opportunity to perform research on human tissue without the concerns inherent in experiments on individual humans. Development of cells in cultures has been found to be greatly influenced by the conditions of the culture. Much work has focused on the effect of the motions of cells in the culture relative to the solution. Recently rotating wall vessels have been used with success in achieving improved cellular cultures. Speculation and limited research have focused on the low shear environment and the ability of rotating vessels to keep cells suspended in solution rather than floating or sedimenting as the primary reasons for the improved cellular cultures using these devices. It is widely believed that the cultures obtained using a rotating wall vessel simulates to some degree the effect of microgravity on cultures. It has also been speculated that the microgravity environment may provide the ideal acceleration environment for culturing of cellular tissues due to the nearly negligible levels of sedimentation and shear possible. This work predicts particle trajectories of cells in rotating wall vessels of cylindrical and annular design consistent with the estimated properties of typical cellular cultures. Estimates of the shear encountered by cells in solution and the interactions with walls are studied. Comparisons of potential experiments in ground and microgravity environments are performed.

  14. Universal depinning transition of domain walls in ultrathin ferromagnets

    NASA Astrophysics Data System (ADS)

    Diaz Pardo, R.; Savero Torres, W.; Kolton, A. B.; Bustingorry, S.; Jeudy, V.

    2017-05-01

    We present a quantitative and comparative study of magnetic-field-driven domain-wall depinning transition in different ferromagnetic ultrathin films over a wide range of temperature. We reveal a universal scaling function accounting for both drive and thermal effects on the depinning transition, including critical exponents. The consistent description we obtain for both the depinning and subthreshold thermally activated creep motion should shed light on the universal glassy dynamics of thermally fluctuating elastic objects pinned by disordered energy landscapes.

  15. Comparison of diagnostic quality of motion picture experts group-2 digital video with super VHS videotape for echocardiographic imaging.

    PubMed

    Harris, Kevin M; Schum, Kevin R; Knickelbine, Thomas; Hurrell, David G; Koehler, Jodi L; Longe, Terrence F

    2003-08-01

    Motion Picture Experts Group-2 (MPEG2) is a broadcast industry standard that allows high-level compression of echocardiographic data. Validation of MPEG2 digital images compared with super VHS videotape has not been previously reported. Simultaneous super VHS videotape and MPEG2 digital images were acquired. In all, 4 experienced echocardiographers completed detailed reporting forms evaluating chamber size, ventricular function, regional wall-motion abnormalities, and measures of valvular regurgitation and stenosis in a blinded fashion. Comparisons between the 2 interpretations were then performed and intraobserver concordance was calculated for the various categories. A total of 80 paired comparisons were made. The overall concordance rate was 93.6% with most of the discrepancies being minor (4.1%). Concordance was 92.4% for left ventricle, 93.2% for right ventricle, 95.2% for regional wall-motion abnormalities, and 97.8% for valve stenosis. The mean grade of valvular regurgitation was similar for the 2 techniques. MPEG2 digital imaging offers excellent concordance compared with super VHS videotape.

  16. An investigation of the cratering-induced motions occurring during the formation of bowl-shaped craters. [using high explosive charges as the cratering source

    NASA Technical Reports Server (NTRS)

    Piekutowski, A. J.

    1980-01-01

    The effects of the dynamic processes which occur during crater formation were examined using small hemispherical high-explosive charges detonated in a tank which had one wall constructed of a thick piece of clear plexiglas. Crater formation and the motions of numerous tracer particles installed in the cratering medium at the medium-wall interface were viewed through the wall of this quarter-space tank and recorded with high-speed cameras. Subsequent study and analysis of particle motions and events recorded on the film provide data needed to develop a time-sequence description of the formation of a bowl-shaped crater. Tables show the dimensions of craters produced in a quarter-space tank compared with dimensions of craters produced in normal half-space tanks. Crater growth rate summaries are also tabulated.

  17. Reproducibility of The Abdominal and Chest Wall Position by Voluntary Breath-Hold Technique Using a Laser-Based Monitoring and Visual Feedback System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nakamura, Katsumasa; Shioyama, Yoshiyuki; Nomoto, Satoru

    2007-05-01

    Purpose: The voluntary breath-hold (BH) technique is a simple method to control the respiration-related motion of a tumor during irradiation. However, the abdominal and chest wall position may not be accurately reproduced using the BH technique. The purpose of this study was to examine whether visual feedback can reduce the fluctuation in wall motion during BH using a new respiratory monitoring device. Methods and Materials: We developed a laser-based BH monitoring and visual feedback system. For this study, five healthy volunteers were enrolled. The volunteers, practicing abdominal breathing, performed shallow end-expiration BH (SEBH), shallow end-inspiration BH (SIBH), and deep end-inspirationmore » BH (DIBH) with or without visual feedback. The abdominal and chest wall positions were measured at 80-ms intervals during BHs. Results: The fluctuation in the chest wall position was smaller than that of the abdominal wall position. The reproducibility of the wall position was improved by visual feedback. With a monitoring device, visual feedback reduced the mean deviation of the abdominal wall from 2.1 {+-} 1.3 mm to 1.5 {+-} 0.5 mm, 2.5 {+-} 1.9 mm to 1.1 {+-} 0.4 mm, and 6.6 {+-} 2.4 mm to 2.6 {+-} 1.4 mm in SEBH, SIBH, and DIBH, respectively. Conclusions: Volunteers can perform the BH maneuver in a highly reproducible fashion when informed about the position of the wall, although in the case of DIBH, the deviation in the wall position remained substantial.« less

  18. Current induced domain wall dynamics in the presence of spin orbit torques

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boulle, O., E-mail: Olivier.boulle@cea.fr; Buda-Prejbeanu, L. D.; Jué, E.

    2014-05-07

    Current induced domain wall (DW) motion in perpendicularly magnetized nanostripes in the presence of spin orbit torques is studied. We show using micromagnetic simulations that the direction of the current induced DW motion and the associated DW velocity depend on the relative values of the field like torque (FLT) and the Slonczewski like torques (SLT). The results are well explained by a collective coordinate model which is used to draw a phase diagram of the DW dynamics as a function of the FLT and the SLT. We show that a large increase in the DW velocity can be reached bymore » a proper tuning of both torques.« less

  19. [Segmental wall movement of the left ventricle in healthy persons and myocardial infarct patients studied by a catheter-less nuclear medical method (camera-cinematography of the heart)].

    PubMed

    Geffers, H; Sigel, H; Bitter, F; Kampmann, H; Stauch, M; Adam, W E

    1976-08-01

    Camera-Kinematography is a nearly noninvasive method to investigate regional motion of the myocard, and allows evaluation of the function of the heart. About 20 min after injection of 15-20 mCi of 99mTC-Human-Serum-Albumin, when the tracer is distributed homogenously within the bloodpool, data acquisition starts. Myocardial wall motion is represented in an appropriate quasi three-dimensional form. In this representation scars can be revealed as "silent" (akinetic) regions, aneurysms by asynchronic motion. Time activity curves for arbitrarily chosen regions can be calculated and give an equivalent for regional volume changes. 16 patients with an old infarction have been investigated. In fourteen cases the location and extent of regions with abnormal motion could be evaluated. Only two cases of a small posterior wall infarction did not show deviations from normal contraction pattern.

  20. Lipid-linked cell wall precursors regulate membrane association of bacterial actin MreB

    PubMed Central

    Schirner, Kathrin; Eun, Ye-Jin; Dion, Mike; Luo, Yun; Helmann, John D.; Garner, Ethan C.; Walker, Suzanne

    2014-01-01

    Summary The bacterial actin homolog MreB, which is critical for rod shape determination, forms filaments that rotate around the cell width on the inner surface of the cytoplasmic membrane. What determines filament association with the membranes or with other cell wall elongation proteins is not known. Using specific chemical and genetic perturbations while following MreB filament motion, we find that MreB membrane association is an actively regulated process that depends on the presence of lipid-linked peptidoglycan precursors. When precursors are depleted, MreB filaments disassemble into the cytoplasm and peptidoglycan synthesis becomes disorganized. In cells that lack wall teichoic acids, but continue to make peptidoglycan, dynamic MreB filaments are observed, although their presence is not sufficient to establish a rod shape. We propose that the cell regulates MreB filament association with the membrane, allowing rapid and reversible inactivation of cell wall enzyme complexes in response to the inhibition of cell wall synthesis. PMID:25402772

  1. Lipid-linked cell wall precursors regulate membrane association of bacterial actin MreB.

    PubMed

    Schirner, Kathrin; Eun, Ye-Jin; Dion, Mike; Luo, Yun; Helmann, John D; Garner, Ethan C; Walker, Suzanne

    2015-01-01

    The bacterial actin homolog MreB, which is crucial for rod shape determination, forms filaments that rotate around the cell width on the inner surface of the cytoplasmic membrane. What determines filament association with the membranes or with other cell wall elongation proteins is not known. Using specific chemical and genetic perturbations while following MreB filament motion, we find that MreB membrane association is an actively regulated process that depends on the presence of lipid-linked peptidoglycan precursors. When precursors are depleted, MreB filaments disassemble into the cytoplasm, and peptidoglycan synthesis becomes disorganized. In cells that lack wall teichoic acids but continue to make peptidoglycan, dynamic MreB filaments are observed, although their presence is not sufficient to establish a rod shape. We propose that the cell regulates MreB filament association with the membrane, allowing rapid and reversible inactivation of cell wall enzyme complexes in response to the inhibition of cell wall synthesis.

  2. 3D mapping of airway wall thickening in asthma with MSCT: a level set approach

    NASA Astrophysics Data System (ADS)

    Fetita, Catalin; Brillet, Pierre-Yves; Hartley, Ruth; Grenier, Philippe A.; Brightling, Christopher

    2014-03-01

    Assessing the airway wall thickness in multi slice computed tomography (MSCT) as image marker for airway disease phenotyping such asthma and COPD is a current trend and challenge for the scientific community working in lung imaging. This paper addresses the same problem from a different point of view: considering the expected wall thickness-to-lumen-radius ratio for a normal subject as known and constant throughout the whole airway tree, the aim is to build up a 3D map of airway wall regions of larger thickness and to define an overall score able to highlight a pathological status. In this respect, the local dimension (caliber) of the previously segmented airway lumen is obtained on each point by exploiting the granulometry morphological operator. A level set function is defined based on this caliber information and on the expected wall thickness ratio, which allows obtaining a good estimate of the airway wall throughout all segmented lumen generations. Next, the vascular (or mediastinal dense tissue) contact regions are automatically detected and excluded from analysis. For the remaining airway wall border points, the real wall thickness is estimated based on the tissue density analysis in the airway radial direction; thick wall points are highlighted on a 3D representation of the airways and several quantification scores are defined. The proposed approach is fully automatic and was evaluated (proof of concept) on a patient selection coming from different databases including mild, severe asthmatics and normal cases. This preliminary evaluation confirms the discriminative power of the proposed approach regarding different phenotypes and is currently extending to larger cohorts.

  3. Simultaneous effects of single wall carbon nanotube and effective variable viscosity for peristaltic flow through annulus having permeable walls

    NASA Astrophysics Data System (ADS)

    Shahzadi, Iqra; Nadeem, S.; Rabiei, Faranak

    The current article deals with the combine effects of single wall carbon nanotubes and effective viscosity for the peristaltic flow of nanofluid through annulus. The nature of the walls is assumed to be permeable. The present theoretical model can be considered as mathematical representation to the motion of conductive physiological fluids in the existence of the endoscope tube which has many biomedical applications such as drug delivery system. The outer tube has a wave of sinusoidal nature that is travelling along its walls while the inner tube is rigid and uniform. Lubrication approach is used for the considered analysis. An empirical relation for the effective variable viscosity of nanofluid is proposed here interestingly. The viscosity of nanofluid is the function of radial distance and the concentration of nanoparticles. Exact solution for the resulting system of equations is displayed for various quantities of interest. The outcomes show that the maximum velocity of SWCNT-blood nanofluid enhances for larger values of viscosity parameter. The pressure gradient in the more extensive part of the annulus is likewise found to increase as a function of variable viscosity parameter. The size of the trapped bolus is also influenced by variable viscosity parameter. The present examination also revealed that the carbon nanotubes have many applications related to biomedicine.

  4. Brownian dynamics of wall tethered polymers in shear flow

    NASA Astrophysics Data System (ADS)

    Lin, Tiras Y.; Saadat, Amir; Kushwaha, Amit; Shaqfeh, Eric S. G.

    2017-11-01

    The dynamics of a wall tethered polymer in shear flow is studied using Brownian dynamics. Simulations are performed with bead-spring chains, and the effect of hydrodynamic interactions (HI) is incorporated through Blake's tensor with a finite size bead correction. We characterize the configuration of the polymer as a function of the Weissenberg number by investigating the regions the polymer explores in both the flow-gradient and flow-vorticity planes. The fractional extension in the flow direction, the width in the vorticity direction, and the thickness in the gradient direction are reported as well, and these quantities are found to compare favorably with the experimental data of the literature. The cyclic motion of the polymer is demonstrated through analysis of the mean velocity field of the end bead. We characterize the collision process of each bead with the wall as a Poisson process and extract an average wall collision rate, which in general varies along the backbone of the chain. The inclusion of HI with the wall for a tethered polymer is found to reduce the average wall collision rate. We anticipate that results from this work will be directly applicable to, e.g., the design of polymer brushes or the use of DNA for making nanowires in molecular electronics. T.Y.L. is supported by the Department of Defense (DoD) through the National Defense Science & Engineering Graduate Fellowship (NDSEG) Program.

  5. A Near-Wall Reynolds-Stress Closure Without Wall Normals

    NASA Technical Reports Server (NTRS)

    Yuan, S. P.; So, R. M. C.

    1997-01-01

    Turbulent wall-bounded complex flows are commonly encountered in engineering practice and are of considerable interest in a variety of industrial applications. The presence of a wall significantly affects turbulence characteristics. In addition to the wall effects, turbulent wall-bounded flows become more complicated by the presence of additional body forces (e.g. centrifugal force and Coriolis force) and complex geometry. Most near-wall Reynolds stress models are developed from a high-Reynolds-number model which assumes turbulence is homogenous (or quasi-homogenous). Near-wall modifications are proposed to include wall effects in near-wall regions. In this process, wall normals are introduced. Good predictions could be obtained by Reynolds stress models with wall normals. However, ambiguity arises when the models are applied in flows with multiple walls. Many models have been proposed to model turbulent flows. Among them, Reynolds stress models, in which turbulent stresses are obtained by solving the Reynolds stress transport equations, have been proved to be the most successful ones. To apply the Reynolds stress models to wall-bounded flows, near-wall corrections accounting for the wall effects are needed, and the resulting models are called near-wall Reynolds stress models. In most of the existing near-wall models, the near-wall corrections invoke wall normals. These wall-dependent near-wall models are difficult to implement for turbulent flows with complex geometry and may give inaccurate predictions due to the ambiguity of wall normals at corners connecting multiple walls. The objective of this study is to develop a more general and flexible near-wall Reynolds stress model without using any wall-dependent variable for wall-bounded turbulent flows. With the aid of near-wall asymptotic analysis and results of direct numerical simulation, a new near-wall Reynolds stress model (NNWRS) is formulated based on Speziale et al.'s high-Reynolds-stress model with wall

  6. Traction reveals mechanisms of wall effects for microswimmers near boundaries

    NASA Astrophysics Data System (ADS)

    Shen, Xinhui; Marcos, Fu, Henry C.

    2017-03-01

    The influence of a plane boundary on low-Reynolds-number swimmers has frequently been studied using image systems for flow singularities. However, the boundary effect can also be expressed using a boundary integral representation over the traction on the boundary. We show that examining the traction pattern on the boundary caused by a swimmer can yield physical insights into determining when far-field multipole models are accurate. We investigate the swimming velocities and the traction of a three-sphere swimmer initially placed parallel to an infinite planar wall. In the far field, the instantaneous effect of the wall on the swimmer is well approximated by that of a multipole expansion consisting of a force dipole and a force quadrupole. On the other hand, the swimmer close to the wall must be described by a system of singularities reflecting its internal structure. We show that these limits and the transition between them can be independently identified by examining the traction pattern on the wall, either using a quantitative correlation coefficient or by visual inspection. Last, we find that for nonconstant propulsion, correlations between swimming stroke motions and internal positions are important and not captured by time-averaged traction on the wall, indicating that care must be taken when applying multipole expansions to study boundary effects in cases of nonconstant propulsion.

  7. Traction reveals mechanisms of wall effects for microswimmers near boundaries.

    PubMed

    Shen, Xinhui; Marcos; Fu, Henry C

    2017-03-01

    The influence of a plane boundary on low-Reynolds-number swimmers has frequently been studied using image systems for flow singularities. However, the boundary effect can also be expressed using a boundary integral representation over the traction on the boundary. We show that examining the traction pattern on the boundary caused by a swimmer can yield physical insights into determining when far-field multipole models are accurate. We investigate the swimming velocities and the traction of a three-sphere swimmer initially placed parallel to an infinite planar wall. In the far field, the instantaneous effect of the wall on the swimmer is well approximated by that of a multipole expansion consisting of a force dipole and a force quadrupole. On the other hand, the swimmer close to the wall must be described by a system of singularities reflecting its internal structure. We show that these limits and the transition between them can be independently identified by examining the traction pattern on the wall, either using a quantitative correlation coefficient or by visual inspection. Last, we find that for nonconstant propulsion, correlations between swimming stroke motions and internal positions are important and not captured by time-averaged traction on the wall, indicating that care must be taken when applying multipole expansions to study boundary effects in cases of nonconstant propulsion.

  8. Inner-outer predictive wall model for wall-bounded turbulence in hypersonic flow

    NASA Astrophysics Data System (ADS)

    Martin, M. Pino; Helm, Clara M.

    2017-11-01

    The inner-outer predictive wall model of Mathis et al. is modified for hypersonic turbulent boundary layers. The model is based on a modulation of the energized motions in the inner layer by large scale momentum fluctuations in the logarithmic layer. Using direct numerical simulation (DNS) data of turbulent boundary layers with free stream Mach number 3 to 10, it is shown that the variation of the fluid properties in the compressible flows leads to large Reynolds number (Re) effects in the outer layer and facilitate the modulation observed in high Re incompressible flows. The modulation effect by the large scale increases with increasing free-stream Mach number. The model is extended to include spanwise and wall-normal velocity fluctuations and is generalized through Morkovin scaling. Temperature fluctuations are modeled using an appropriate Reynolds Analogy. Density fluctuations are calculated using an equation of state and a scaling with Mach number. DNS data are used to obtain the universal signal and parameters. The model is tested by using the universal signal to reproduce the flow conditions of Mach 3 and Mach 7 turbulent boundary layer DNS data and comparing turbulence statistics between the modeled flow and the DNS data. This work is supported by the Air Force Office of Scientific Research under Grant FA9550-17-1-0104.

  9. Interaction of flexible surface hairs with near-wall turbulence.

    PubMed

    Brücker, Ch

    2011-05-11

    The interaction of near-wall turbulence with hairy surfaces is investigated in a turbulent boundary layer flow along a flat plate in an oil channel at Re = 1.2 × 10⁶. The plate is covered locally with a dense carpet of elastomeric micro-hairs (length L = 1 mm, length in viscous units L( + ) = 30) which are arranged in a regular grid (60 × 30 hairs with a streamwise spacing Δx( + )≈15 and a spanwise spacing Δy( + )≈30). Instead of the micro-structures used in previous studies for sensory applications, the surface hairs are considerably larger and much more densely distributed with a spacing of S/D < 5 such that they interact with each other by flow coupling. The non-fluctuating mean part of the flow forces a substantial pre-bending in the streamwise direction (reconfiguration). As a consequence, the hairs align with the streamwise direction, thus imposing anisotropic damping characteristics with regard to flow fluctuations in streamwise and spanwise or wall-normal directions. Near-wall high-frequency disturbances excited by the passage of turbulent sweeps are dampened over their course along the carpet. The cooperative action of the hairs leads to an energy transfer from small-scale motion to larger scales, thus increasing the coherence of the motion pattern in streamwise and spanwise directions. As a consequence of the specific arrangement of the micro-hairs in streamwise columns a reduced spanwise meandering and stabilization of the streamwise velocity streaks is achieved by promoting varicose waves and inhibiting sinusoidal waves. Streak stabilization is known to be a major contributor to turbulent drag reduction. Thus it is concluded that hairy surfaces may be of benefit for turbulent drag reduction as hypothesized by Bartenwerfer and Bechert (1991 Z. Flugwiss. Weltraumforsch. 15 19-26).

  10. Model of vertical plasma motion during the current quench

    NASA Astrophysics Data System (ADS)

    Breizman, Boris; Kiramov, Dmitrii

    2017-10-01

    Tokamak disruptions impair plasma position control, which allows the plasma column to move and hit the wall. These detrimental events enhance thermal and mechanical loads due to halo currents and runaway electron losses. Their fundamental understanding and prevention is one of the high-priority items for ITER. As commonly observed in experiments, the disruptive plasma tends to move vertically, and the timescale of this motion is rather resistive than Alfvenic. These observations suggest that the plasma column is nearly force-free during its vertical motion. In fact, the force-free constraint is already used in disruption simulators. In this work, we consider a geometrically simple system that mimics the tokamak plasma surrounded by the conducting structures. Using this model, we highlight the underlying mechanism of the vertical displacement events during the current quench phase of plasma disruption. We also address a question of ideal MHD stability of the plasma during its resistive motion. Work supported by the U.S. Department of Energy Contracts DEFG02-04ER54742 and DE-SC0016283.

  11. On the Motion of an Annular Film in Microgravity Gas-Liquid Flow

    NASA Technical Reports Server (NTRS)

    McQuillen, John B.

    2002-01-01

    Three flow regimes have been identified for gas-liquid flow in a microgravity environment: Bubble, Slug, and Annular. For the slug and annular flow regimes, the behavior observed in vertical upflow in normal gravity is similar to microgravity flow with a thin, symmetrical annular film wetting the tube wall. However, the motion and behavior of this film is significantly different between the normal and low gravity cases. Specifically, the liquid film will slow and come to a stop during low frequency wave motion or slugging. In normal gravity vertical upflow, the film has been observed to slow, stop, and actually reverse direction until it meets the next slug or wave.

  12. Could quantitative longitudinal peak systolic strain help in the detection of left ventricular wall motion abnormalities in our daily echocardiographic practice?

    PubMed

    Benyounes, Nadia; Lang, Sylvie; Gout, Olivier; Ancédy, Yann; Etienney, Arnaud; Cohen, Ariel

    2016-10-01

    Transthoracic echocardiography is the most commonly used tool for the detection of left ventricular wall motion (LVWM) abnormalities using "naked eye evaluation". This subjective and operator-dependent technique requires a high level of clinical training and experience. Two-dimensional speckle-tracking echocardiography (2D-STE), which is less operator-dependent, has been proposed for this purpose. However, the role of on-line segmental longitudinal peak systolic strain (LPSS) values in the prediction of LVWM has not been fully evaluated. To test segmental LPSS for predicting LVWM abnormalities in routine echocardiography laboratory practice. LVWM was evaluated by an experienced cardiologist, during routine practice, in 620 patients; segmental LPSS values were then calculated. In this work, reflecting real life, 99.6% of segments were successfully tracked. Mean (95% confidence interval [CI]) segmental LPSS values for normal basal (n=3409), mid (n=3468) and apical (n=3466) segments were -16.7% (-16.9% to -16.5%), -18.2% (-18.3% to -18.0%) and -21.1% (-21.3% to -20.9%), respectively. Mean (95% CI) segmental LPSS values for hypokinetic basal (n=114), mid (n=116) and apical (n=90) segments were -7.7% (-9.0% to -6.3%), -10.1% (-11.1% to -9.0%) and -9.3% (-10.5% to -8.1%), respectively. Mean (95% CI) segmental LPSS values for akinetic basal (n=128), mid (n=95) and apical (n=91) segments were -6.6% (-8.0% to -5.1%), -6.1% (-7.7% to -4.6%) and -4.2% (-5.4% to -3.0%), respectively. LPSS allowed the differentiation between normal and abnormal segments at basal, mid and apical levels. An LPSS value≥-12% detected abnormal segmental motion with a sensitivity of 78% for basal, 70% for mid and 82% for apical segments. Segmental LPSS values may help to differentiate between normal and abnormal left ventricular segments. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  13. Effect of high-pitch dual-source CT to compensate motion artifacts: a phantom study.

    PubMed

    Farshad-Amacker, Nadja A; Alkadhi, Hatem; Leschka, Sebastian; Frauenfelder, Thomas

    2013-10-01

    To evaluate the potential of high-pitch, dual-source computed tomography (DSCT) for compensation of motion artifacts. Motion artifacts were created using a moving chest/cardiac phantom with integrated stents at different velocities (from 0 to 4-6 cm/s) parallel (z direction), transverse (x direction), and diagonal (x and z direction combined) to the scanning direction using standard-pitch (SP) (pitch = 1) and high-pitch (HP) (pitch = 3.2) 128-detector DSCT (Siemens, Healthcare, Forchheim, Germany). The scanning parameters were (SP/HP): tube voltage, 120 kV/120 kV; effective tube current time product, 300 mAs/500 mAs; and a pitch of 1/3.2. Motion artifacts were analyzed in terms of subjective image quality and object distortion. Image quality was rated by two blinded, independent observers using a 4-point scoring system (1, excellent; 2, good with minor object distortion or blurring; 3, diagnostically partially not acceptable; and 4, diagnostically not acceptable image quality). Object distortion was assessed by the measured changes of the object's outer diameter (x) and length (z) and a corresponding calculated distortion vector (d) (d = √(x(2) + z(2))). The interobserver agreement was excellent (k = 0.91). Image quality using SP was diagnostically not acceptable with any motion in x direction (scores 3 and 4), in contrast to HP DSCT where it remained diagnostic up to 2 cm/s (scores 1 and 2). For motion in the z direction only, image quality remained diagnostic for SP and HP DSCT (scores 1 and 2). Changes of the object's diameter (x), length (z), and distortion vectors (d) were significantly greater with SP (overall: x = 1.9 cm ± 1.7 cm, z = 0.6 cm ± 0.8 cm, and d = 1.4 cm ± 1.5 cm) compared to HP DSCT (overall: x = 0.1 cm ± 0.1 cm, z = 0.0 cm ± 0.1 cm, and d = 0.1 cm ± 0.1 cm; each P < .05). High-pitch DSCT significantly decreases motion artifacts in various directions and improves image quality. Copyright © 2013 AUR. Published by Elsevier Inc. All rights

  14. Unsteady Motions in Combustion Chambers for Propulsion Systems

    DTIC Science & Technology

    2006-12-01

    Internal Heat Conduction on the Propagation of Acoustic 5-10 Waves 5.4 Energy and Intensity Associated with Acoustic Waves 5-13 5.5 The Growth or... Heat Source and Motion of the Boundary 6-16 6.6 Rayleigh’s Criterion and Linear Stability 6-18 6.7 Some Results for Linear Stability in Three...7.11.1 Pulsing Solid Propellant Rockets 7-45 7.12 Dependence of Wall Heat Transfer on the Amplitude of Oscillations 7-52 7.13 One Way to Analyze

  15. Influence of proton-pump inhibitors on stomach wall uptake of 99mTc-tetrofosmin in cadmium-zinc-telluride SPECT myocardial perfusion imaging.

    PubMed

    Mouden, Mohamed; Rijkee, Karlijn S; Schreuder, Nanno; Timmer, Jorik R; Jager, Pieter L

    2015-02-01

    Proton-pump inhibitors (PPIs) induce potentially interfering stomach wall activity in single-photon emission computed tomography myocardial perfusion imaging (SPECT-MPI) with technetium-99m ((99m)Tc)-sestamibi. However, no data are available for (99m)Tc-tetrofosmin. We assessed the influence of prolonged (>2 weeks) PPI use on the stomach wall uptake of (99m)Tc-tetrofosmin in patients referred for stress MPI with a cadmium-zinc-telluride-based SPECT camera and its relation with dyspepsia symptoms. Consecutive patients (n=127) underwent a 1-day adenosine stress-first SPECT-MPI with (99m)Tc-tetrofosmin, of whom 54 (43%) patients had been on PPIs for more than 2 weeks. Stomach wall activity was identified on stress SPECT using computed tomographic attenuation maps and was scored using a four-point grading scale into clinically relevant (scores 2 or 3) or nonrelevant (scores 0 or 1).Patients on PPIs had stomach wall uptake more frequently as compared with patients not using PPIs (22 vs. 7%, P=0.017). Dyspepsia was similar in both groups. Prolonged use of PPIs is associated with stomach wall uptake of (99m)Tc-tetrofosmin in stress cadmium-zinc-telluride-SPECT images. Gastric symptoms were not associated with stomach wall uptake.

  16. Chronic abdominal wall pain misdiagnosed as functional abdominal pain.

    PubMed

    van Assen, Tijmen; de Jager-Kievit, Jenneke W A J; Scheltinga, Marc R; Roumen, Rudi M H

    2013-01-01

    The abdominal wall is often neglected as a cause of chronic abdominal pain. The aim of this study was to identify chronic abdominal wall pain syndromes, such as anterior cutaneous nerve entrapment syndrome (ACNES), in a patient population diagnosed with functional abdominal pain, including irritable bowel syndrome, using a validated 18-item questionnaire as an identification tool. In this cross-sectional analysis, 4 Dutch primary care practices employing physicians who were unaware of the existence of ACNES were selected. A total of 535 patients ≥18 years old who were registered with a functional abdominal pain diagnosis were approached when they were symptomatic to complete the questionnaire (maximum 18 points). Responders who scored at least the 10-point cutoff value (sensitivity, 0.94; specificity, 0.92) underwent a diagnostic evaluation to establish their final diagnosis. The main outcome was the presence and prevalence of ACNES in a group of symptomatic patients diagnosed with functional abdominal pain. Of 535 patients, 304 (57%) responded; 167 subjects (31%) recently reporting symptoms completed the questionnaire. Of 23 patients who scored above the 10-point cutoff value, 18 were available for a diagnostic evaluation. In half of these subjects (n = 9) functional abdominal pain (including IBS) was confirmed. However, the other 9 patients were suffering from abdominal wall pain syndrome, 6 of whom were diagnosed with ACNES (3.6% prevalence rate of symptomatic subjects; 95% confidence interval, 1.7-7.6), whereas the remaining 3 harbored a painful lipoma, an abdominal herniation, and a painful scar. A clinically relevant portion of patients previously diagnosed with functional abdominal pain syndrome in a primary care environment suffers from an abdominal wall pain syndrome such as ACNES.

  17. Experimental Estimation Of Energy Damping During Free Rocking Of Unreinforced Masonry Walls. First Results

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sorrentino, Luigi; Masiani, Renato; Benedetti, Stefano

    2008-07-08

    This paper presents an ongoing experimental program on unreinforced masonry walls undergoing free rocking. Aim of the laboratory campaign is the estimation of kinetic energy damping exhibited by walls released with non-zero initial conditions of motion. Such energy damping is necessary for dynamic modelling of unreinforced masonry local mechanisms. After a brief review of the literature on this topic, the main features of the laboratory tests are presented. The program involves the experimental investigation of several parameters: 1) unit material (brick or tuff), 2) wall aspect ratio (ranging between 14.5 and 7.1), 3) restraint condition (two-sided or one-sided rocking), andmore » 4) depth of the contact surface between facade and transverse walls (one-sided rocking only). All walls are single wythe and the mortar is pozzuolanic. The campaign is still in progress. However, it is possible to present the results on most of the mechanical properties of mortar and bricks. Moreover, a few time histories are reported, already indicating the need to correct some of the assumptions frequent in the literature.« less

  18. Shearing of nanoscopic bridges in two-component thin liquid layers between chemically patterned walls.

    PubMed

    Hemming, C J; Patey, G N

    2004-10-01

    Bridge phases associated with a phase transition between two liquid phases occur when a two-component liquid mixture is confined between chemically patterned walls. In the bulk the liquid mixture with components A, B undergoes phase separation into an A-rich phase and a B-rich phase. The walls bear stripes attractive to A. In the bridge phase A-rich and B-rich regions alternate. Grand canonical Monte Carlo studies are performed with the alignment between stripes on opposite walls varied. Misalignment of the stripes places the nanoscopic liquid bridges under shear strain. The bridges exert a Hookean restoring force on the walls for small displacements from equilibrium. As the strain increases there are deviations from Hooke's law. Eventually there is an abrupt yielding of the bridges. Molecular dynamics simulations show the bridges form or disintegrate on time scales which are fast compared to wall motion and transport of molecules into or from the confined space. Some interesting possible applications of the phenomena are discussed. (c) 2004 American Institute of Physics

  19. Bio-mathematical analysis for the peristaltic flow of single wall carbon nanotubes under the impact of variable viscosity and wall properties.

    PubMed

    Shahzadi, Iqra; Sadaf, Hina; Nadeem, Sohail; Saleem, Anber

    2017-02-01

    The main objective of this paper is to study the Bio-mathematical analysis for the peristaltic flow of single wall carbon nanotubes under the impact of variable viscosity and wall properties. The right and the left walls of the curved channel possess sinusoidal wave that is travelling along the outer boundary. The features of the peristaltic motion are determined by using long wavelength and low Reynolds number approximation. Exact solutions are determined for the axial velocity and for the temperature profile. Graphical results have been presented for velocity profile, temperature and stream function for various physical parameters of interest. Symmetry of the curved channel is disturbed for smaller values of the curvature parameter. It is found that the altitude of the velocity profile increases for larger values of variable viscosity parameter for both the cases (pure blood as well as single wall carbon nanotubes). It is detected that velocity profile increases with increasing values of rigidity parameter. It is due to the fact that an increase in rigidity parameter decreases tension in the walls of the blood vessels which speeds up the blood flow for pure blood as well as single wall carbon nanotubes. Increase in Grashof number decreases the fluid velocity. This is due to the reason that viscous forces play a prominent role that's why increase in Grashof number decreases the velocity profile. It is also found that temperature drops for increasing values of nanoparticle volume fraction. Basically, higher thermal conductivity of the nanoparticles plays a key role for quick heat dissipation, and this justifies the use of the single wall carbon nanotubes in different situations as a coolant. Exact solutions are calculated for the temperature and the velocity profile. Symmetry of the curved channel is destroyed due to the curvedness for velocity, temperature and contour plots. Addition of single wall carbon nanotubes shows a decrease in fluid temperature. Trapping

  20. Directed collective motion of bacteria under channel confinement

    NASA Astrophysics Data System (ADS)

    Wioland, H.; Lushi, E.; Goldstein, R. E.

    2016-07-01

    Dense suspensions of swimming bacteria are known to exhibit collective behaviour arising from the interplay of steric and hydrodynamic interactions. Unconfined suspensions exhibit transient, recurring vortices and jets, whereas those confined in circular domains may exhibit order in the form of a spiral vortex. Here we show that confinement into a long and narrow macroscopic ‘racetrack’ geometry stabilises bacterial motion to form a steady unidirectional circulation. This motion is reproduced in simulations of discrete swimmers that reveal the crucial role that bacteria-driven fluid flows play in the dynamics. In particular, cells close to the channel wall produce strong flows which advect cells in the bulk against their swimming direction. We examine in detail the transition from a disordered state to persistent directed motion as a function of the channel width, and show that the width at the crossover point is comparable to the typical correlation length of swirls seen in the unbounded system. Our results shed light on the mechanisms driving the collective behaviour of bacteria and other active matter systems, and stress the importance of the ubiquitous boundaries found in natural habitats.

  1. Feasibility study of an aerial manipulator interacting with a vertical wall

    DTIC Science & Technology

    2017-06-01

    each blade . Some tests are run with different levels of PWM input and the resultant angular acceleration in each case is measured with the motion...Helicopter Near a Vertical Surface ...................29 Figure 15. Near-Wall Moment for a Single Blade Helicopter. Source: [30]. .............30...with canted propellers is proposed, so that each blade applies thrust with components in the vertical and in the horizontal plane. In Figure 10

  2. Motion Recognition and Modifying Motion Generation for Imitation Robot Based on Motion Knowledge Formation

    NASA Astrophysics Data System (ADS)

    Okuzawa, Yuki; Kato, Shohei; Kanoh, Masayoshi; Itoh, Hidenori

    A knowledge-based approach to imitation learning of motion generation for humanoid robots and an imitative motion generation system based on motion knowledge learning and modification are described. The system has three parts: recognizing, learning, and modifying parts. The first part recognizes an instructed motion distinguishing it from the motion knowledge database by the continuous hidden markov model. When the motion is recognized as being unfamiliar, the second part learns it using locally weighted regression and acquires a knowledge of the motion. When a robot recognizes the instructed motion as familiar or judges that its acquired knowledge is applicable to the motion generation, the third part imitates the instructed motion by modifying a learned motion. This paper reports some performance results: the motion imitation of several radio gymnastics motions.

  3. Balance and ankle range of motion in community-dwelling women aged 64 to 87 years: a correlational study.

    PubMed

    Mecagni, C; Smith, J P; Roberts, K E; O'Sullivan, S B

    2000-10-01

    This study investigated the relationship between balance measures and ankle range of motion (ROM) in community-dwelling elderly women with no health problems. Identification of modifiable factors associated with balance may enable clinicians to design treatments to help reduce the risk of falls in elderly people. The sample consisted of 34 women between the ages of 64 and 87 years (mean=74.7, SD=6.0). Goniometry was used to determine bilateral ankle active-assistive range of motion (AAROM) and passive range of motion. Balance capabilities were measured with the Functional Reach Test (FRT) and the Tinetti Performance-Oriented Mobility Assessment (POMA). Balance data for the FRT, POMA balance subtest, POMA gait subtest, and POMA total score were correlated with ankle ROM using the Pearson product moment correlation coefficient (PCC). Correlations between ROM and balance scores were found, ranging from.29 to.63. The POMA gait subtest and FRT resulted in higher correlations with ROM than did the POMA balance subtest (left total AAROM PCC=.63,.51, and.31). Correlations using composite ankle ROM scores were higher than individual motions. The strongest correlation existed between bilateral, total ankle AAROM and the POMA gait subtest scores (PCC=. 63) Correlations exist between ankle ROM and balance in community-dwelling elderly women. Additional research is needed to determine whether treatment directed at increasing ankle ROM can improve balance.

  4. Estrogen receptor expression and vessel density in the vagina wall in postmenopausal women with prolapse.

    PubMed

    Lara, Lúcia Alves da Silva; Ribeiro da Silva, Alfredo; Rosa-e-Silva, Julio Cesar; Silva-de-Sá, Marcos Felipe; Rosa-e-Silva, Ana Carolina Japur de Sá

    2014-04-01

    After menopause, critically estrogen low levels result in modifications in vaginal wall. This cross-sectional study aims to determine whether there is a change in the number of vessels in the lamina propria of the vagina after menopause in parallel to the ER-alpha expression on the vaginal wall. Twelve women who underwent a genital surgery for genital prolapse up to grade II were selected. They were divided into two groups: a premenopausal group (PG) consisting of six women who were 18-40 years old with FSH levels =12 mIU/ml and regular cycles, and a menopausal group (MG) consisting of six women at least one year after menopause who were <65 years old with FSH levels =40 mIU/ml. Slides were stained for ER-alpha immunohistochemistry, and an endothelial cell marker CD3 was used to label vessels which were identified by using a system for morphometry. The number of vessels was significantly higher in the PG than in the MG both on the anterior wall (PG: 1.055 ± 145.8 vessels/mm(2), MG: 346.6 ± 209.9 vessels/mm(2), p<0.0001) and on the posterior wall (PG: 1064 ± 303.3 vessels/mm(2), MG: 348.6 ± 167.3 vessels/mm(2), p=0.0005). The ER-alpha score was significantly higher in the PG than the score for the MG on both the anterior and posterior walls (PG: 6.0 ± 0.52, MG: 2.5 ± 0.89, p=0.007; PG: 5.8 ± 0.79, MG: 2.7 ± 0.95, p=0.03, respectively). There was a positive correlation between the ER-alpha score and the vessel concentration on the anterior (r=0.6656, p=0.018) and posterior (r=0.6738, p=0.016) vaginal walls. Age was strongly negatively correlated with vessel concentration on the vaginal walls (respectively r=-0.9033, p<0.0001, r=-0.7440, p=0.0055). Therefore, postmenopausal women with genital prolapse have a smaller number of vessels on the vaginal wall compared to normoestrogenic controls with the same pathological condition. Hypoestrogenism and advancing age are factors that are associated to these changes. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Modification of equation of motion of fluid-conveying pipe for laminar and turbulent flow profiles

    NASA Astrophysics Data System (ADS)

    Guo, C. Q.; Zhang, C. H.; Païdoussis, M. P.

    2010-07-01

    Considering the non-uniformity of the flow velocity distribution in fluid-conveying pipes caused by the viscosity of real fluids, the centrifugal force term in the equation of motion of the pipe is modified for laminar and turbulent flow profiles. The flow-profile-modification factors are found to be 1.333, 1.015-1.040 and 1.035-1.055 for laminar flow in circular pipes, turbulent flow in smooth-wall circular pipes and turbulent flow in rough-wall circular pipes, respectively. The critical flow velocities for divergence in the above-mentioned three cases are found to be 13.4%, 0.74-1.9% and 1.7-2.6%, respectively, lower than that with plug flow, while those for flutter are even lower, which could reach 36% for the laminar flow profile. By introducing two new concepts of equivalent flow velocity and equivalent mass, fluid-conveying pipe problems with different flow profiles can be solved with the equation of motion for plug flow.

  6. Effect of personalized external aortic root support on aortic root motion and distension in Marfan syndrome patients.

    PubMed

    Izgi, Cemil; Nyktari, Evangelia; Alpendurada, Francisco; Bruengger, Annina Studer; Pepper, John; Treasure, Tom; Mohiaddin, Raad

    2015-10-15

    Personalized external aortic root support (PEARS) is a novel surgical approach with the aim of stabilizing the aortic root size and decreasing risk of dissection in Marfan syndrome patients. A bespoke polymer mesh tailored to each patient's individual aorta shape is produced by modeling and then surgically implanted. The aim of this study is to assess the mechanical effects of PEARS on the aortic root systolic downward motion (an important determinant of aortic wall stress), aortic root distension and on the left ventricle (LV). A cohort of 27 Marfan patients had a prophylactic PEARS surgery between 2004 and 2012 with 24 having preoperative and follow-up cardiovascular magnetic resonance imaging studies. Systolic downward aortic root motion, aortic root distension, LV volumes/mass and mitral annular systolic excursion before the operation and in the latest follow-up were measured randomly and blinded. After a median follow-up of 50.5 (IQR 25.5-72) months following implantation of PEARS, systolic downward motion of aortic root was significantly decreased (12.6±3.6mm pre-operation vs 7.9±2.9mm latest follow-up, p<0.00001). There was a tendency for a decrease in systolic aortic root distension but this was not significant (median 4.5% vs 2%, p=0.35). There was no significant change in LV volumes, ejection fraction, mass and mitral annular systolic excursion in follow-up. PEARS surgery decreases systolic downward aortic root motion which is an important determinant of longitudinal aortic wall stress. Aortic wall distension and Windkessel function are not significantly impaired in the follow-up after implantation of the mesh which is also supported by the lack of deterioration of LV volumes or mass. Crown Copyright © 2015. Published by Elsevier Ireland Ltd. All rights reserved.

  7. Coherent structures in wall-bounded turbulence.

    PubMed

    Dennis, David J C

    2015-01-01

    The inherent difficulty of understanding turbulence has led to researchers attacking the topic in many different ways over the years of turbulence research. Some approaches have been more successful than others, but most only deal with part of the problem. One approach that has seen reasonable success (or at least popularity) is that of attempting to deconstruct the complex and disorganised turbulent flow field into to a set of motions that are in some way organised. These motions are generally called "coherent structures". There are several strands to this approach, from identifying the coherent structures within the flow, defining their characteristics, explaining how they are created, sustained and destroyed, to utilising their features to model the turbulent flow. This review considers research on coherent structures in wall-bounded turbulent flows: a class of flow which is extremely interesting to many scientists (mainly, but not exclusively, physicists and engineers) due to their prevalence in nature, industry and everyday life. This area has seen a lot of activity, particularly in recent years, much of which has been driven by advances in experimental and computational techniques. However, several ideas, developed many years ago based on flow visualisation and intuition, are still both informative and relevant. Indeed, much of the more recent research is firmly indebted to some of the early pioneers of the coherent structures approach. Therefore, in this review, selected historical research is discussed along with the more contemporary advances in an attempt to provide the reader with a good overview of how the field has developed and to highlight the perspicacity of some of the early researchers, as well as providing an overview of our current understanding of the role of coherent structures in wall-bounded turbulent flows.

  8. Magnetoresistance devices based on single-walled carbon nanotubes

    NASA Astrophysics Data System (ADS)

    Hod, Oded; Rabani, Eran; Baer, Roi

    2005-08-01

    We demonstrate the physical principles for the construction of a nanometer-sized magnetoresistance device based on the Aharonov-Bohm effect [Phys. Rev. 115, 485 (1959)]. The proposed device is made of a short single-walled carbon nanotube (SWCNT) placed on a substrate and coupled to a tip/contacts. We consider conductance due to the motion of electrons along the circumference of the tube (as opposed to the motion parallel to its axis). We find that the circumference conductance is sensitive to magnetic fields threading the SWCNT due to the Aharonov-Bohm effect, and show that by retracting the tip/contacts, so that the coupling to the SWCNT is reduced, very high sensitivity to the threading magnetic field develops. This is due to the formation of a narrow resonance through which the tunneling current flows. Using a bias potential the resonance can be shifted to low magnetic fields, allowing the control of conductance with magnetic fields of the order of 1 T.

  9. Global motion perception is related to motor function in 4.5-year-old children born at risk of abnormal development

    PubMed Central

    Chakraborty, Arijit; Anstice, Nicola S.; Jacobs, Robert J.; Paudel, Nabin; LaGasse, Linda L.; Lester, Barry M.; McKinlay, Christopher J. D.; Harding, Jane E.; Wouldes, Trecia A.; Thompson, Benjamin

    2017-01-01

    Global motion perception is often used as an index of dorsal visual stream function in neurodevelopmental studies. However, the relationship between global motion perception and visuomotor control, a primary function of the dorsal stream, is unclear. We measured global motion perception (motion coherence threshold; MCT) and performance on standardized measures of motor function in 606 4.5-year-old children born at risk of abnormal neurodevelopment. Visual acuity, stereoacuity and verbal IQ were also assessed. After adjustment for verbal IQ or both visual acuity and stereoacuity, MCT was modestly, but significantly, associated with all components of motor function with the exception of gross motor scores. In a separate analysis, stereoacuity, but not visual acuity, was significantly associated with both gross and fine motor scores. These results indicate that the development of motion perception and stereoacuity are associated with motor function in pre-school children. PMID:28435122

  10. Pilot study on objective measurement of abdominal wall strength in patients with ventral incisional hernia.

    PubMed

    Parker, Michael; Goldberg, Ross F; Dinkins, Maryane M; Asbun, Horacio J; Daniel Smith, C; Preissler, Susanne; Bowers, Steven P

    2011-11-01

    Outcomes after ventral incisional hernia (VIH) repair are measured by recurrence rate and subjective measures. No objective metrics evaluate functional outcomes after abdominal wall reconstruction. This study aimed to develop testing of abdominal wall strength (AWS) that could be validated as a useful metric. Data were prospectively collected during 9 months from 35 patients. A total of 10 patients were evaluated before and after VIH repair, for a total of 45 encounters. The patients were tested simultaneously or in succession by two of three examiners. Data were collected for three tests: double leg lowering (DLL), trunk raising (TR), and supine reaching (SR). Raw data were compared and tested for validity, and continuous data were transformed to categorical data. Agreement was measured using the intraclass correlation coefficient (ICC) for DLL and using kappa for the ordinal measures. Simultaneous testing yielded the following interobserver reliability: DLL (0.96 and 0.87), TR (1.00 and 0.95), and SR (0.76). Reproducibility was assessed by consecutive tests, with correlation as follows: DLL (0.81), TR (0.81), and RCH (0.21). Due to poor interobserver reliability for the SR test compared with the DLL and TR tests, the SR test was excluded from calculation of an overall score. Based on raw data distribution from the DLL and TR tests, the DLL data were categorized into 10º increments, allowing construction of a 10-point score. The median AWS score was 5 (interquartile range [IQR], 4-7), and there was agreement within 1 point for 42 of the 45 encounters (93%). The findings from this study demonstrate that the 10-point AWS score may measure AWS in an accurate and reproducible fashion, with potential for objective description of abdominal wall function of VIH patients. This score may help to identify patients suited for abdominal wall reconstruction while measuring progress after VIH repair. Further longitudinal outcomes studies are needed.

  11. Simultaneous dynamic characterization of charge and structural motion during ferroelectric switching

    NASA Astrophysics Data System (ADS)

    Kwamen, C.; Rössle, M.; Reinhardt, M.; Leitenberger, W.; Zamponi, F.; Alexe, M.; Bargheer, M.

    2017-10-01

    Monitoring structural changes in ferroelectric thin films during electric field induced polarization switching is important for a full microscopic understanding of the coupled motion of charges, atoms, and domain walls in ferroelectric nanostructures. We combine standard ferroelectric test sequences of switching and nonswitching electrical pulses with time-resolved x-ray diffraction to investigate the structural response of a nanoscale Pb (Zr0.2Ti0.8) O3 ferroelectric oxide capacitor upon charging, discharging, and polarization reversal. We observe that a nonlinear piezoelectric response of the ferroelectric layer develops on a much longer time scale than the R C time constant of the device. The complex atomic motion during the ferroelectric polarization reversal starts with a contraction of the lattice, whereas the expansive piezoelectric response sets in after considerable charge flow due to the applied voltage pulses on the electrodes of the capacitor. Our simultaneous measurements on a working device elucidate and visualize the complex interplay of charge flow and structural motion and challenges theoretical modeling.

  12. The relationship between human field motion and preferred visible wavelengths.

    PubMed

    Benedict, S C; Burge, J M

    1990-01-01

    The purpose of this study was to investigate the relationship between human field motion and preferred visible wavelengths. The study was based on the principle of resonancy from Rogers' science of unitary human beings; 201 subjects were tested using a modified version of Ference's human field motion test (HFMT). Two matrices of color were projected to provide an environment for the measurement of preferred visible wavelengths. There was no statistically significant relationship (r = 0.0387, p = 0.293) between scores on the human field motion test and preferred visible wavelengths as measured in nanometers. The Rogerian concept of accelerated human field rhythms being coordinate with higher frequency environment patterns was not supported in this study. Questions concerning the validity of the HFMT were expressed and were based upon the ambiguity of the terminology of the instrument and the lack of understanding of the concepts used to describe human field motion. Recommendations include the use of other methods to study Rogers' framework, and the development of other instrumentation to measure human field motion.

  13. Scoring Dawg Core Breakoff and Retention Mechanism

    NASA Technical Reports Server (NTRS)

    Badescu, Mircea; Sherrit, Stewart; Bar-Cohen, Yoseph; Bao, Xiaoqi; Backes, Paul G.

    2011-01-01

    This novel core break-off and retention mechanism consists of a scoring dawg controlled by a set of two tubes (a drill tube and an inner tube). The drill tube and the inner tube have longitudinal concentric holes. The solution can be implemented in an eccentric tube configuration as well where the tubes have eccentric longitudinal holes. The inner tube presents at the bottom two control surfaces for controlling the orientation of the scoring dawg. The drill tube presents a sunk-in profile on the inside of the wall for housing the scoring dawg. The inner tube rotation relative to the drill tube actively controls the orientation of the scoring dawg and hence its penetration and retrieval from the core. The scoring dawg presents a shaft, two axially spaced arms, and a tooth. The two arms slide on the control surfaces of the inner tube. The tooth, when rotated, can penetrate or be extracted from the core. During drilling, the two tubes move together maintaining the scoring dawg completely outside the core. After the desired drilling depth has been reached the inner tube is rotated relative to the drill tube such that the tooth of the scoring dawg moves toward the central axis. By rotating the drill tube, the scoring dawg can score the core and so reduce its cross sectional area. The scoring dawg can also act as a stress concentrator for breaking the core in torsion or tension. After breaking the core, the scoring dawg can act as a core retention mechanism. For scoring, it requires the core to be attached to the rock. If the core is broken, the dawg can be used as a retention mechanism. The scoring dawg requires a hard-tip insert like tungsten carbide for scoring hard rocks. The relative rotation of the two tubes can be controlled manually or by an additional actuator. In the implemented design solution the bit rotation for scoring was in the same direction as the drilling. The device was tested for limestone cores and basalt cores. The torque required for breaking the

  14. Study on the effect of the infill walls on the seismic performance of a reinforced concrete frame

    NASA Astrophysics Data System (ADS)

    Zhang, Cuiqiang; Zhou, Ying; Zhou, Deyuan; Lu, Xilin

    2011-12-01

    Motivated by the seismic damage observed to reinforced concrete (RC) frame structures during the Wenchuan earthquake, the effect of infill walls on the seismic performance of a RC frame is studied in this paper. Infill walls, especially those made of masonry, offer some amount of stiffness and strength. Therefore, the effect of infill walls should be considered during the design of RC frames. In this study, an analysis of the recorded ground motion in the Wenchuan earthquake is performed. Then, a numerical model is developed to simulate the infill walls. Finally, nonlinear dynamic analysis is carried out on a RC frame with and without infill walls, respectively, by using CANNY software. Through a comparative analysis, the following conclusions can be drawn. The failure mode of the frame with infill walls is in accordance with the seismic damage failure pattern, which is strong beam and weak column mode. This indicates that the infill walls change the failure pattern of the frame, and it is necessary to consider them in the seismic design of the RC frame. The numerical model presented in this paper can effectively simulate the effect of infill walls on the RC frame.

  15. Iterative User Interface Design for Automated Sequential Organ Failure Assessment Score Calculator in Sepsis Detection

    PubMed Central

    Herasevich, Vitaly

    2017-01-01

    Background The new sepsis definition has increased the need for frequent sequential organ failure assessment (SOFA) score recalculation and the clerical burden of information retrieval makes this score ideal for automated calculation. Objective The aim of this study was to (1) estimate the clerical workload of manual SOFA score calculation through a time-motion analysis and (2) describe a user-centered design process for an electronic medical record (EMR) integrated, automated SOFA score calculator with subsequent usability evaluation study. Methods First, we performed a time-motion analysis by recording time-to-task-completion for the manual calculation of 35 baseline and 35 current SOFA scores by 14 internal medicine residents over a 2-month period. Next, we used an agile development process to create a user interface for a previously developed automated SOFA score calculator. The final user interface usability was evaluated by clinician end users with the Computer Systems Usability Questionnaire. Results The overall mean (standard deviation, SD) time-to-complete manual SOFA score calculation time was 61.6 s (33). Among the 24% (12/50) usability survey respondents, our user-centered user interface design process resulted in >75% favorability of survey items in the domains of system usability, information quality, and interface quality. Conclusions Early stakeholder engagement in our agile design process resulted in a user interface for an automated SOFA score calculator that reduced clinician workload and met clinicians’ needs at the point of care. Emerging interoperable platforms may facilitate dissemination of similarly useful clinical score calculators and decision support algorithms as “apps.” A user-centered design process and usability evaluation should be considered during creation of these tools. PMID:28526675

  16. Reliability of provocative tests of motion sickness susceptibility

    NASA Technical Reports Server (NTRS)

    Calkins, D. S.; Reschke, M. F.; Kennedy, R. S.; Dunlop, W. P.

    1987-01-01

    Test-retest reliability values were derived from motion sickness susceptibility scores obtained from two successive exposures to each of three tests: (1) Coriolis sickness sensitivity test; (2) staircase velocity movement test; and (3) parabolic flight static chair test. The reliability of the three tests ranged from 0.70 to 0.88. Normalizing values from predictors with skewed distributions improved the reliability.

  17. Training Effectiveness of Visual and Motion Simulation

    DTIC Science & Technology

    1981-01-01

    and checkride scores. No statistical differeLes between the two groups were found. Creelman (1959) reported that students trained in theSNJ Link with...simulated and aircraft hvurs or sorsies (Dricisom a Burger, 1976; Brown. Matheny, & Fleaman. 1951; Creelman , 1959; Gray et al., 1969- Payne at al., 1976...reirtionohip between flight simulator motion and trainiag requirmumenia. Human Factors. 1979. 2). 493-50)1. Creelman , J.A. Evaluation of approach

  18. Motion sickness is linked to nystagmus-related trigeminal brain stem input: a new hypothesis.

    PubMed

    Gupta, Vinod Kumar

    2005-01-01

    Motion sickness is a common and distressing but poorly understood syndrome associated with nausea/vomiting and autonomic nervous system accompaniments that develops in the air or space as well as on sea or land. A bidirectional aetiologic link prevails between migraine and motion-sickness. Motion sickness provokes jerk nystagmus induced by both optokinetic and vestibular stimulation. Fixation of gaze or closure of eyes generally prevents motion sickness while vestibular otolithic function is eliminated in microgravity of space, indicating a predominant pathogenetic role for visuo-sensory input. Scopolamine, dimenhydrinate, and promethazine reduce motion-related nystagmus. Contraction of extraocular muscles generates proprioceptive neural traffic and can provoke an ocular hypertensive response. It is proposed that repetitive contractions of the extraocular muscles during motion-related jerk nystagmus rapidly augment brain stem afferent input by increasing proprioceptive neural traffic through connections of the oculomotor nerves with the ophthalmic nerve in the lateral wall of the cavernous sinus as well as by raising the intraocular pressure thereby stimulating anterior segment ocular trigeminal nerve fibers. This verifiable hypothesis defines the pathophysiological basis of individual susceptibility to motion sickness, elucidates the preventive mechanism of gaze fixation or ocular closure, advances the aetiologic link between MS and migraine, rationalizes the mechanism of known preventive drugs, and explores new therapeutic possibilities.

  19. Physiologic Simulation of the Fontan Surgery with Variable Wall Properties and Respiration

    NASA Astrophysics Data System (ADS)

    Long, Christopher; Bazilevs, Yuri; Feinstein, Jeffrey; Marsden, Alison

    2010-11-01

    Children born with single ventricle heart defects typically undergo a surgical procedure known as a total cavopulmonary connection (TCPC). The goal of this work is to perform hemodynamic simulations accounting for motion of the arterial walls in the TCPC. We perform fluid structure interactions (FSI) simulations using an Arbitrary Lagrangian Eulerian (ALE) finite element framework into a patient-specific model of the TCPC. The patient's post-op anatomy is reconstructed from MRI data. Respiration rate, heart rate, and venous pressures are obtained from catheterization data, and flowrates are obtained from phase contrast MRI data and are used together with a respiratory model. Lumped parameter (RCR) boundary conditions are used at the outlets. This study is the first to introduce variable elastic properties for the different areas of the TCPC, including a Gore-Tex conduit. Quantities such as wall shear stresses and pressures at critical junctions are extracted from the simulation and are compared with pressure tracings from clinical data as well as with rigid wall simulations.

  20. Trajectory and chirality of vortex domain walls in ferromagnetic nanowires with an asymmetric Y-branch

    NASA Astrophysics Data System (ADS)

    Brandão, J.; Mello, A.; Garcia, F.; Sampaio, L. C.

    2017-03-01

    The motion and trajectory of vortex domain walls (VDWs) driven by magnetic field were investigated in Fe80Ni20 nanowires with an asymmetric Y-shape branch. By using the focused magneto-optical Kerr effect, we have probed the injection, pinning, and propagation of VDWs in the branch and in the wire beyond the branch entrance. Hysteresis cycles measured at these points show 3 and 4 jumps in the magnetization reversal, respectively. Micromagnetic simulations were carried out to obtain the number of jumps in the hysteresis cycles, and the magnetization process involved in each jump. Based on simulations and from the size of the jumps in the measured hysteresis cycles, one obtains the histogram of the domain wall type probability. While in the branch domain walls of different types are equiprobable, in the nanowire vortex domain walls with counter clockwise and clockwise chiralities and transverse-down domain walls are measured with probabilities of 65%, 25%, and 10%, respectively. These results provide an additional route to select the trajectory and chirality of VDWs in magnetic nanostructures.

  1. Analysis of intra-uterine fluid motion induced by uterine contractions.

    PubMed

    Eytan, O; Elad, D

    1999-03-01

    Evaluation of the fluid flow pattern in a non-pregnant uterus is important for understanding embryo transport in the uterus. Fertilization occurs in the fallopian tube and the embryo (fertilized ovum) enters the uterine cavity within 3 days of ovulation. In the uterus, the embryo is conveyed by the uterine fluid for another 3 to 4 days to a successful implantation site at the upper part of the uterus. Fluid movements within the uterus may be induced by several mechanisms, but they seem to be dominated by myometrial contractions. Intra-uterine fluid transport in a sagittal cross-section of the uterus was simulated by a model of wall-induced fluid motion within a two-dimensional channel. The time-dependent fluid pattern was studied by employing the lubrication theory. A comprehensive analysis of peristaltic transport resulting from symmetric and asymmetric contractions is presented for various displacement waves on the channel walls. The results provide information on the flow field and possible trajectories by which an embryo may be transported before implantation at the uterine wall.

  2. Andreas Acrivos Dissertation Award Talk: Modeling drag forces and velocity fluctuations in wall-bounded flows at high Reynolds numbers

    NASA Astrophysics Data System (ADS)

    Yang, Xiang

    2017-11-01

    The sizes of fluid motions in wall-bounded flows scale approximately as their distances from the wall. At high Reynolds numbers, resolving near-wall, small-scale, yet momentum-transferring eddies are computationally intensive, and to alleviate the strict near-wall grid resolution requirement, a wall model is usually used. The wall model of interest here is the integral wall model. This model parameterizes the near-wall sub-grid velocity profile as being comprised of a linear inner-layer and a logarithmic meso-layer with one additional term that accounts for the effects of flow acceleration, pressure gradients etc. We use the integral wall model for wall-modeled large-eddy simulations (WMLES) of turbulent boundary layers over rough walls. The effects of rough-wall topology on drag forces are investigated. A rough-wall model is then developed based on considerations of such effects, which are now known as mutual sheltering among roughness elements. Last, we discuss briefly a new interpretation of the Townsend attached eddy hypothesis-the hierarchical random additive process model (HRAP). The analogy between the energy cascade and the momentum cascade is mathematically formal as HRAP follows the multi-fractal formulism, which was extensively used for the energy cascade.

  3. The internal-external respiratory motion correlation is unaffected by audiovisual biofeedback.

    PubMed

    Steel, Harry; Pollock, Sean; Lee, Danny; Keall, Paul; Kim, Taeho

    2014-03-01

    This study evaluated if an audiovisual (AV) biofeedback causes variation in the level of external and internal correlation due to its interactive intervention in natural breathing. The internal (diaphragm) and external (abdominal wall) respiratory motion signals of 15 healthy human subjects under AV biofeedback and free breathing (FB) were analyzed and measures of correlation and regularity taken. Regularity metrics (root mean square error and spectral power dispersion metric) were obtained and the correlation between these metrics and the internal and external correlation was investigated. For FB and AV biofeedback assisted breathing the mean correlations found between internal and external respiratory motion were 0.96±0.02 and 0.96±0.03, respectively. This means there is no evidence to suggest (p-value=0.88) any difference in the correlation between internal and external respiratory motion with the use of AV biofeedback. Our results confirmed the hypothesis that the internal-external correlation with AV biofeedback is the same as for free breathing. Should this correlation be maintained for patients, AV biofeedback can be implemented in the clinic with confidence as regularity improvements using AV biofeedback with an external signal will be reflected in increased internal motion regularity.

  4. Magnetic properties, domain-wall creep motion, and the Dzyaloshinskii-Moriya interaction in Pt/Co/Ir thin films

    NASA Astrophysics Data System (ADS)

    Shepley, Philippa M.; Tunnicliffe, Harry; Shahbazi, Kowsar; Burnell, Gavin; Moore, Thomas A.

    2018-04-01

    We study the magnetic properties of perpendicularly magnetized Pt/Co/Ir thin films and investigate the domain-wall creep method of determining the interfacial Dzyaloshinskii-Moriya (DM) interaction in ultrathin films. Measurements of the Co layer thickness dependence of saturation magnetization, perpendicular magnetic anisotropy, and symmetric and antisymmetric (i.e., DM) exchange energies in Pt/Co/Ir thin films have been made to determine the relationship between these properties. We discuss the measurement of the DM interaction by the expansion of a reverse domain in the domain-wall creep regime. We show how the creep parameters behave as a function of in-plane bias field and discuss the effects of domain-wall roughness on the measurement of the DM interaction by domain expansion. Whereas modifications to the creep law with DM field and in-plane bias fields have taken into account changes in the energy barrier scaling parameter α , we find that both α and the velocity scaling parameter v0 change as a function of in-plane bias field.

  5. The association between left ventricular twisting motion and mechanical dyssynchrony: a three-dimensional speckle tracking study.

    PubMed

    Fujiwara, Shohei; Komamura, Kazuo; Nakabo, Ayumi; Masaki, Mitsuru; Fukui, Miho; Sugahara, Masataka; Itohara, Kanako; Soyama, Yuko; Goda, Akiko; Hirotani, Shinichi; Mano, Toshiaki; Masuyama, Tohru

    2016-02-01

    Left ventricular (LV) dyssynchrony is a causal factor in LV dysfunction and thought to be associated with LV twisting motion. We tested whether three-dimensional speckle tracking (3DT) can be used to evaluate the relationship between LV twisting motion and dyssynchrony. We examined 25 patients with sick sinus syndrome who had received dual chamber pacemakers. The acute effects of ventricular pacing on LV wall motion after the switch from atrial to ventricular pacing were assessed. LV twisting motion and dyssynchrony during each pacing mode were measured using 3DT. LV dyssynchrony was calculated from the time to the minimum peak systolic area strain of 16 LV imaging segments. Ventricular pacing increased LV dyssynchrony and decreased twist and torsion. A significant correlation was observed between changes in LV dyssynchrony and changes in torsion (r = -0.65, p < 0.01). Evaluation of LV twisting motion can potentially be used for diagnosing LV dyssynchrony.

  6. Application of constrained k-means clustering in ground motion simulation validation

    NASA Astrophysics Data System (ADS)

    Khoshnevis, N.; Taborda, R.

    2017-12-01

    The validation of ground motion synthetics has received increased attention over the last few years due to the advances in physics-based deterministic and hybrid simulation methods. Unlike for low frequency simulations (f ≤ 0.5 Hz), for which it has become reasonable to expect a good match between synthetics and data, in the case of high-frequency simulations (f ≥ 1 Hz) it is not possible to match results on a wiggle-by-wiggle basis. This is mostly due to the various complexities and uncertainties involved in earthquake ground motion modeling. Therefore, in order to compare synthetics with data we turn to different time series metrics, which are used as a means to characterize how the synthetics match the data on qualitative and statistical sense. In general, these metrics provide GOF scores that measure the level of similarity in the time and frequency domains. It is common for these scores to be scaled from 0 to 10, with 10 representing a perfect match. Although using individual metrics for particular applications is considered more adequate, there is no consensus or a unified method to classify the comparison between a set of synthetic and recorded seismograms when the various metrics offer different scores. We study the relationship among these metrics through a constrained k-means clustering approach. We define 4 hypothetical stations with scores 3, 5, 7, and 9 for all metrics. We put these stations in the category of cannot-link constraints. We generate the dataset through the validation of the results from a deterministic (physics-based) ground motion simulation for a moderate magnitude earthquake in the greater Los Angeles basin using three velocity models. The maximum frequency of the simulation is 4 Hz. The dataset involves over 300 stations and 11 metrics, or features, as they are understood in the clustering process, where the metrics form a multi-dimensional space. We address the high-dimensional feature effects with a subspace-clustering analysis

  7. Steato-Score: Non-Invasive Quantitative Assessment of Liver Fat by Ultrasound Imaging.

    PubMed

    Di Lascio, Nicole; Avigo, Cinzia; Salvati, Antonio; Martini, Nicola; Ragucci, Monica; Monti, Serena; Prinster, Anna; Chiappino, Dante; Mancini, Marcello; D'Elia, Domenico; Ghiadoni, Lorenzo; Bonino, Ferruccio; Brunetto, Maurizia R; Faita, Francesco

    2018-05-04

    Non-alcoholic fatty liver disease is becoming a global epidemic. The aim of this study was to develop a system for assessing liver fat content based on ultrasound images. Magnetic resonance spectroscopy measurements were obtained in 61 patients and the controlled attenuation parameter in 54. Ultrasound images were acquired for all 115 participants and used to calculate the hepatic/renal ratio, hepatic/portal vein ratio, attenuation rate, diaphragm visualization and portal vein wall visualization. The Steato-score was obtained by combining these five parameters. Magnetic resonance spectroscopy measurements were significantly correlated with hepatic/renal ratio, hepatic/portal vein ratio, attenuation rate, diaphragm visualization and portal vein wall visualization; Steato-score was dependent on hepatic/renal ratio, attenuation rate and diaphragm visualization. Area under the receiver operating characteristic curve was equal to 0.98, with 89% sensitivity and 94% specificity. Controlled attenuation parameter values were significantly correlated with hepatic/renal ratio, attenuation rate, diaphragm visualization and Steato-score; the area under the curve was 0.79. This system could be a valid alternative as a non-invasive, simple and inexpensive assessment of intrahepatic fat. Copyright © 2018 World Federation for Ultrasound in Medicine and Biology. Published by Elsevier Inc. All rights reserved.

  8. Wall characterization for through-the-wall radar applications

    NASA Astrophysics Data System (ADS)

    Greneker, Gene; Rausch, E. O.

    2008-04-01

    There has been continuing interest in the penetration of multilayer building materials, such as wood walls with air gaps and concrete hollow core block, using through-the-wall (TTW) radar systems. TTW operational techniques and signal propagation paths vary depending on how the TTW system is intended to be operated. For example, the operator of a TTW radar may be required to place the radar against the intervening wall of interest while collecting data. Other operational doctrines allow the radar to be operated in a stand-off mode from the wall. The stand-off distances can vary from feet to hundreds of feet, depending on the type of radar being used. When a signal is propagated through a multilayer wall with air gaps between the material and the wall construction uses materials of radically different dielectric constants, attenuation may not be the only effect that the probing signal experiences passing through the wall. This paper presents measurements of a hollow core concrete block wall and the measurement of a standard wall constructed of siding and wallboard. Both types of walls are typically found in most U.S. homes. These limited measurements demonstrate that the type of wall being penetrated by a wideband signal can modify the probing signal.

  9. Current-driven domain wall motion based memory devices: Application to a ratchet ferromagnetic strip

    NASA Astrophysics Data System (ADS)

    Sánchez-Tejerina, Luis; Martínez, Eduardo; Raposo, Víctor; Alejos, Óscar

    2018-04-01

    Ratchet memories, where perpendicular magnetocristalline anisotropy is tailored so as to precisely control the magnetic transitions, has been recently proven to be a feasible device to store and manipulate data bits. For such devices, it has been shown that the current-driven regime of domain walls can improve their performances with respect to the field-driven one. However, the relaxing time required by the traveling domain walls constitutes a certain drawback if the former regime is considered, since it results in longer device latencies. In order to speed up the bit shifting procedure, it is demonstrated here that the application of a current of inverse polarity during the DW relaxing time may reduce such latencies. The reverse current must be sufficiently high as to drive the DW to the equilibrium position faster than the anisotropy slope itself, but with an amplitude sufficiently low as to avoid DW backward shifting. Alternatively, it is possible to use such a reverse current to increase the proper range of operation for a given relaxing time, i.e., the pair of values of the current amplitude and pulse time that ensures single DW jumps for a certain latency time.

  10. Large scale structures in a turbulent boundary layer and their imprint on wall shear stress

    NASA Astrophysics Data System (ADS)

    Pabon, Rommel; Barnard, Casey; Ukeiley, Lawrence; Sheplak, Mark

    2015-11-01

    Experiments were performed on a turbulent boundary layer developing on a flat plate model under zero pressure gradient flow. A MEMS differential capacitive shear stress sensor with a 1 mm × 1 mm floating element was used to capture the fluctuating wall shear stress simultaneously with streamwise velocity measurements from a hot-wire anemometer traversed in the wall normal direction. Near the wall, the peak in the cross correlation corresponds to an organized motion inclined 45° from the wall. In the outer region, the peak diminishes in value, but is still significant at a distance greater than half the boundary layer thickness, and corresponds to a structure inclined 14° from the wall. High coherence between the two signals was found for the low-frequency content, reinforcing the belief that large scale structures have a vital impact on wall shear stress. Thus, estimation of the wall shear stress from the low-frequency velocity signal will be performed, and is expected to be statistically significant in the outer boundary layer. Additionally, conditionally averaged mean velocity profiles will be presented to assess the effects of high and low shear stress. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship under Grant No. DGE-1315138.

  11. A Near-Wall Reynolds-Stress Closure without Wall Normals

    NASA Technical Reports Server (NTRS)

    Yuan, S. P.; So, R. M. C.

    1997-01-01

    With the aid of near-wall asymptotic analysis and results of direct numerical simulation, a new near-wall Reynolds stress model (NNWRS) is formulated based on the SSG high-Reynolds-stress model with wall-independent near-wall corrections. Only one damping function is used for flows with a wide range of Reynolds numbers to ensure that the near-wall modifications diminish away from the walls. The model is able to reproduce complicated flow phenomena induced by complex geometry, such as flow recirculation, reattachment and boundary-layer redevelopment in backward-facing step flow and secondary flow in three-dimensional square duct flow. In simple flows, including fully developed channel/pipe flow, Couette flow and boundary-layer flow, the wall effects are dominant, and the NNWRS model predicts less degree of turbulent anisotropy in the near-wall region compared with a wall-dependent near-wall Reynolds Stress model (NWRS) developed by So and colleagues. The comparison of the predictions given by the two models rectifies the misconception that the overshooting of skin friction coefficient in backward-facing step flow prevalent in those near-wall, models with wall normal is caused by he use of wall normal.

  12. Multi-scale AM-FM motion analysis of ultrasound videos of carotid artery plaques

    NASA Astrophysics Data System (ADS)

    Murillo, Sergio; Murray, Victor; Loizou, C. P.; Pattichis, C. S.; Pattichis, Marios; Barriga, E. Simon

    2012-03-01

    An estimated 82 million American adults have one or more type of cardiovascular diseases (CVD). CVD is the leading cause of death (1 of every 3 deaths) in the United States. When considered separately from other CVDs, stroke ranks third among all causes of death behind diseases of the heart and cancer. Stroke accounts for 1 out of every 18 deaths and is the leading cause of serious long-term disability in the United States. Motion estimation of ultrasound videos (US) of carotid artery (CA) plaques provides important information regarding plaque deformation that should be considered for distinguishing between symptomatic and asymptomatic plaques. In this paper, we present the development of verifiable methods for the estimation of plaque motion. Our methodology is tested on a set of 34 (5 symptomatic and 29 asymptomatic) ultrasound videos of carotid artery plaques. Plaque and wall motion analysis provides information about plaque instability and is used in an attempt to differentiate between symptomatic and asymptomatic cases. The final goal for motion estimation and analysis is to identify pathological conditions that can be detected from motion changes due to changes in tissue stiffness.

  13. Global motion perception is related to motor function in 4.5-year-old children born at risk of abnormal development.

    PubMed

    Chakraborty, Arijit; Anstice, Nicola S; Jacobs, Robert J; Paudel, Nabin; LaGasse, Linda L; Lester, Barry M; McKinlay, Christopher J D; Harding, Jane E; Wouldes, Trecia A; Thompson, Benjamin

    2017-06-01

    Global motion perception is often used as an index of dorsal visual stream function in neurodevelopmental studies. However, the relationship between global motion perception and visuomotor control, a primary function of the dorsal stream, is unclear. We measured global motion perception (motion coherence threshold; MCT) and performance on standardized measures of motor function in 606 4.5-year-old children born at risk of abnormal neurodevelopment. Visual acuity, stereoacuity and verbal IQ were also assessed. After adjustment for verbal IQ or both visual acuity and stereoacuity, MCT was modestly, but significantly, associated with all components of motor function with the exception of fine motor scores. In a separate analysis, stereoacuity, but not visual acuity, was significantly associated with both gross and fine motor scores. These results indicate that the development of motion perception and stereoacuity are associated with motor function in pre-school children. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Shear-driven motion of supported lipid bilayers in microfluidic channels.

    PubMed

    Jönsson, Peter; Beech, Jason P; Tegenfeldt, Jonas O; Höök, Fredrik

    2009-04-15

    In this work, we demonstrate how a lateral motion of a supported lipid bilayer (SLB) and its constituents can be created without relying on self-spreading forces. The force driving the SLB is instead a viscous shear force arising from a pressure-driven bulk flow acting on the SLB that is formed on a glass wall inside a microfluidic channel. In contrast to self-spreading bilayers, this method allows for accurate control of the bilayer motion by altering the bulk flow in the channel. Experiments showed that an egg yolk phosphatidylcholine SLB formed on a glass support moved in a rolling motion under these shear forces, with the lipids in the upper leaflet of the bilayer moving at twice the velocity of the bilayer front. The drift velocity of different lipid probes in the SLB was observed to be sensitive to the interactions between the lipid probe and the surrounding molecules, resulting in drift velocities that varied by up to 1 order of magnitude for the different lipid probes in our experiments. Since the method provides a so far unattainable control of the motion of all molecules in an SLB, we foresee great potential for this technique, alone or in combination with other methods, for studies of lipid bilayers and different membrane-associated molecules.

  15. Viscous near-wall flow in a wake of circular cylinder at moderate Reynolds numbers

    NASA Astrophysics Data System (ADS)

    Okhotnikov, D. I.; Molochnikov, V. M.; Mazo, A. B.; Malyukov, A. V.; Goltsman, A. E.; Saushin, I. I.

    2017-11-01

    Here we present the results of experimental investigation of a cross flow around a circular cylinder mounted near the wall of a channel with rectangular cross section. The experiments were carried out in the range of Reynolds numbers corresponding to the transition to turbulence in a wake of the cylinder. Flow visualization and SIV-measurements of instantaneous velocity fields were carried out. Evolution of the flow pattern behind the cylinder and formation of the regular vortex structures were analyzed. It is shown that in the case of flow around the cylinder, there is no spiral motion of fluid from the side walls of the channel towards its symmetry plane, typical of the flow around a spanwise rib located on the channel wall. The laminar-turbulent transition in the wake of the cylinder is caused by the shear layer instability.

  16. Experimental study of the laminar-turbulent transition of a concave wall in a parallel flow

    NASA Technical Reports Server (NTRS)

    Bippes, H.

    1978-01-01

    The instability of the laminar boundary layer flow along a concave wall was studied. Observations of these three-dimensional boundary layer phenomena were made using the hydrogen-bubble visualization technique. With the application of stereo-photogrammetric methods in the air-water system it was possible to investigate the flow processes qualitatively and quantitatively. In the case of a concave wall of sufficient curvature, a primary instability occurs first in the form of Goertler vortices with wave lengths depending upon the boundary layer thickness and the wall curvature. At the onset the amplification rate is in agreement with the linear theory. Later, during the non-linear amplification stage, periodic spanwise vorticity concentrations develop in the low velocity region between the longitudinal vortices. Then a meandering motion of the longitudinal vortex streets subsequently ensues, leading to turbulence.

  17. Self-Motion and the Shaping of Sensory Signals

    PubMed Central

    Jenks, Robert A.; Vaziri, Ashkan; Boloori, Ali-Reza

    2010-01-01

    Sensory systems must form stable representations of the external environment in the presence of self-induced variations in sensory signals. It is also possible that the variations themselves may provide useful information about self-motion relative to the external environment. Rats have been shown to be capable of fine texture discrimination and object localization based on palpation by facial vibrissae, or whiskers, alone. During behavior, the facial vibrissae brush against objects and undergo deflection patterns that are influenced both by the surface features of the objects and by the animal's own motion. The extent to which behavioral variability shapes the sensory inputs to this pathway is unknown. Using high-resolution, high-speed videography of unconstrained rats running on a linear track, we measured several behavioral variables including running speed, distance to the track wall, and head angle, as well as the proximal vibrissa deflections while the distal portions of the vibrissae were in contact with periodic gratings. The measured deflections, which serve as the sensory input to this pathway, were strongly modulated both by the properties of the gratings and the trial-to-trial variations in head-motion and locomotion. Using presumed internal knowledge of locomotion and head-rotation, gratings were classified using short-duration trials (<150 ms) from high-frequency vibrissa motion, and the continuous trajectory of the animal's own motion through the track was decoded from the low frequency content. Together, these results suggest that rats have simultaneous access to low- and high-frequency information about their environment, which has been shown to be parsed into different processing streams that are likely important for accurate object localization and texture coding. PMID:20164407

  18. Numerical study of acoustophoretic motion of particles in a PDMS microchannel driven by surface acoustic waves.

    PubMed

    Nama, Nitesh; Barnkob, Rune; Mao, Zhangming; Kähler, Christian J; Costanzo, Francesco; Huang, Tony Jun

    2015-06-21

    We present a numerical study of the acoustophoretic motion of particles suspended in a liquid-filled PDMS microchannel on a lithium niobate substrate acoustically driven by surface acoustic waves. We employ a perturbation approach where the flow variables are divided into first- and second-order fields. We use impedance boundary conditions to model the PDMS microchannel walls and we model the acoustic actuation by a displacement function from the literature based on a numerical study of piezoelectric actuation. Consistent with the type of actuation, the obtained first-order field is a horizontal standing wave that travels vertically from the actuated wall towards the upper PDMS wall. This is in contrast to what is observed in bulk acoustic wave devices. The first-order fields drive the acoustic streaming, as well as the time-averaged acoustic radiation force acting on suspended particles. We analyze the motion of suspended particles driven by the acoustic streaming drag and the radiation force. We examine a range of particle diameters to demonstrate the transition from streaming-drag-dominated acoustophoresis to radiation-force-dominated acoustophoresis. Finally, as an application of our numerical model, we demonstrate the capability to tune the position of the vertical pressure node along the channel width by tuning the phase difference between two incoming surface acoustic waves.

  19. Three-dimensional knee motion before and after high tibial osteotomy for medial knee osteoarthritis.

    PubMed

    Takemae, Takashi; Omori, Go; Nishino, Katsutoshi; Terajima, Kazuhiro; Koga, Yoshio; Endo, Naoto

    2006-11-01

    High tibial osteotomy (HTO) is an established surgical option for treating medial knee osteoarthritis. HTO moves the mechanical load on the knee joint from the medial compartment to the lateral compartment by changing the leg alignment, but the effects of the operation remain unclear. The purpose of this study was to evaluate the change in three-dimensional knee motion before and after HTO, focusing on lateral thrust and screw home movement, and to investigate the relationship between the change in knee motion and the clinical results. A series of 19 patients with medial knee osteoarthritis who had undergone HTO were evaluated. We performed a clinical assessment, radiological evaluation, and motion analysis at 2.4 years postoperatively. The clinical assessment was performed using the Japanese Orthopaedic Association knee score. The score was significantly improved in all patients after operation. Motion analysis revealed that lateral thrust, which was observed in 18 of the 20 knees before operation, was reduced to 7 knees after operation. Regarding active terminal extension of the knee, three patterns of rotational movement were observed before operation: screw home movement (external rotation), reverse screw home movement (internal rotation), and no rotation. By contrast, after operation, only reverse screw home movement and no rotation were observed; the screw home movement disappeared in all patients. In the knees with reverse screw home movement after operation, the preoperative score was significantly lower than those in the knees with no rotation after operation. Kinetically, HTO was useful for suppressing lateral thrust in medial knee osteoarthritis, although the rotational movement of the knee joint was unchanged.

  20. DBIO Best Thesis Award: Mechanics, Dynamics, and Organization of the Bacterial Cytoskeleton and Cell Wall

    NASA Astrophysics Data System (ADS)

    Wang, Siyuan

    2012-02-01

    Bacteria come in a variety of shapes. While the peptidoglycan (PG) cell wall serves as an exoskeleton that defines the static cell shape, the internal bacterial cytoskeleton mediates cell shape by recruiting PG synthesis machinery and thus defining the pattern of cell-wall synthesis. While much is known about the chemistry and biology of the cytoskeleton and cell wall, much of their biophysics, including essential aspects of the functionality, dynamics, and organization, remain unknown. This dissertation aims to elucidate the detailed biophysical mechanisms of cytoskeleton guided wall synthesis. First, I find that the bacterial cytoskeleton MreB contributes nearly as much to the rigidity of an Escherichia coli cell as the cell wall. This conclusion implies that the cytoskeletal polymer MreB applies meaningful force to the cell wall, an idea favored by theoretical modeling of wall growth, and suggests an evolutionary origin of cytoskeleton-governed cell rigidity. Second, I observe that MreB rotates around the long axis of E. coli, and the motion depends on wall synthesis. This is the first discovery of a cell-wall assembly driven molecular motor in bacteria. Third, I prove that both cell-wall synthesis and the PG network have chiral ordering, which is established by the spatial pattern of MreB. This work links the molecular structure of the cytoskeleton and of the cell wall with organismal-scale behavior. Finally, I develop a mathematical model of cytoskeleton-cell membrane interactions, which explains the preferential orientation of different cytoskeleton components in bacteria.

  1. Study of droplet flow in a T-shape microchannel with bottom wall fluctuation

    NASA Astrophysics Data System (ADS)

    Pang, Yan; Wang, Xiang; Liu, Zhaomiao

    2018-03-01

    Droplet generation in a T-shape microchannel, with a main channel width of 50 μm , side channel width of 25 μm, and height of 50 μm, is simulated to study the effects of the forced fluctuation of the bottom wall. The periodic fluctuations of the bottom wall are applied on the near junction part of the main channel in the T-shape microchannel. Effects of bottom wall's shape, fluctuation periods, and amplitudes on the droplet generation are covered in the research of this protocol. In the simulation, the average size is affected a little by the fluctuations, but significantly by the fixed shape of the deformed bottom wall, while the droplet size range is expanded by the fluctuations under most of the conditions. Droplet sizes are distributed in a periodic pattern with small amplitude along the relative time when the fluctuation is forced on the bottom wall near the T-junction, while the droplet emerging frequency is not varied by the fluctuation. The droplet velocity is varied by the bottom wall motion, especially under the shorter period and the larger amplitude. When the fluctuation period is similar to the droplet emerging period, the droplet size is as stable as the non-fluctuation case after a development stage at the beginning of flow, while the droplet velocity is varied by the moving wall with the scope up to 80% of the average velocity under the conditions of this investigation.

  2. A near-wall four-equation turbulence model for compressible boundary layers

    NASA Technical Reports Server (NTRS)

    Sommer, T. P.; So, R. M. C.; Zhang, H. S.

    1992-01-01

    A near-wall four-equation turbulence model is developed for the calculation of high-speed compressible turbulent boundary layers. The four equations used are the k-epsilon equations and the theta(exp 2)-epsilon(sub theta) equations. These equations are used to define the turbulent diffusivities for momentum and heat fluxes, thus allowing the assumption of dynamic similarity between momentum and heat transport to be relaxed. The Favre-averaged equations of motion are solved in conjunction with the four transport equations. Calculations are compared with measurements and with another model's predictions where the assumption of the constant turbulent Prandtl number is invoked. Compressible flat plate turbulent boundary layers with both adiabatic and constant temperature wall boundary conditions are considered. Results for the range of low Mach numbers and temperature ratios investigated are essentially the same as those obtained using an identical near-wall k-epsilon model. In general, the numerical predictions are in very good agreement with measurements and there are significant improvements in the predictions of mean flow properties at high Mach numbers.

  3. Acoustic microstreaming due to an ultrasound contrast microbubble near a wall

    NASA Astrophysics Data System (ADS)

    Mobadersany, Nima; Sarkar, Kausik

    2017-11-01

    In an ultrasound field, in addition to the sinusoidal motion of fluid particles, particles experience a steady streaming velocity due to nonlinear second order effects. Here, we have simulated the microstreaming flow near a plane rigid wall caused by the pulsations of contrast microbubbles. Although these microbubbles were initially developed as a contrast enhancing agents for ultrasound imaging, they generate additional therapeutic effects that can be harnessed for targeted drug delivery or blood brain barrier (BBB) opening. The microbubbles have a gas core coated with a stabilizing layer of lipids or proteins. We use analytical models as well as boundary element (BEM) simulation to simulate the flow around these bubbles implementing interfacial rheology models for the coating. The microstreaming flow is characterized by two wall bounded vortices. The size of the vortices decreases with the decrease of the separation from the wall. The vortex-induced shear stress is simulated and analyzed as a function of excitation parameters and geometry. These microstreaming shear stress plays a critical role in increasing the membrane permeability facilitating drug delivery or rupturing biological tissues.

  4. The stability of individual patterns of autonomic responses to motion sickness stimulation

    NASA Technical Reports Server (NTRS)

    Cowings, Patricia S.; Toscano, William B.; Naifeh, Karen H.

    1990-01-01

    As part of a program to develop a treatment for motion sickness based on self-regulation of autonomic nervous system (ANS) activity, this study examined the stability of an individual's pattern of ANS responses to motion sickness stimulation on repeated occasions. Motion sickness symptoms were induced in 58 people during two rotating chair test. Physiological responses measured were heart rate, finger pulse volume, respiration rate, and skin conductance. Using standard scores, stability of responses of specific magnitudes across both tests is as examined. Correlational analyses, analysis of variance, and a components of variance analysis all revealed marked, but quite stable, individual differences in ANS responses to both mild and severe motion sickness. These findings confirm the prior observation that people are sufficiently unique in their ANS responses to motion sickness provocation to make it nesessary to individually tailor self-regulation training. Further, these data support the contention that individual ANS patterns are sufficiently consistent from test to test so as to serve as an objective indicator of individual motion sickness malaise levels.

  5. Motion sickness in cats - A symptom rating scale used in laboratory and flight tests

    NASA Technical Reports Server (NTRS)

    Suri, K. B.; Daunton, N. G.; Crampton, G. H.

    1979-01-01

    The cat is proposed as a model for the study of motion and space sickness. Development of a scale for rating the motion sickness severity in the cat is described. The scale is used to evaluate an antimotion sickness drug, d-amphetamine plus scopolamine, and to determine whether it is possible to predict sickness susceptibility during parabolic flight, including zero-G maneuvers, from scores obtained during ground based trials.

  6. Iterative User Interface Design for Automated Sequential Organ Failure Assessment Score Calculator in Sepsis Detection.

    PubMed

    Aakre, Christopher Ansel; Kitson, Jaben E; Li, Man; Herasevich, Vitaly

    2017-05-18

    The new sepsis definition has increased the need for frequent sequential organ failure assessment (SOFA) score recalculation and the clerical burden of information retrieval makes this score ideal for automated calculation. The aim of this study was to (1) estimate the clerical workload of manual SOFA score calculation through a time-motion analysis and (2) describe a user-centered design process for an electronic medical record (EMR) integrated, automated SOFA score calculator with subsequent usability evaluation study. First, we performed a time-motion analysis by recording time-to-task-completion for the manual calculation of 35 baseline and 35 current SOFA scores by 14 internal medicine residents over a 2-month period. Next, we used an agile development process to create a user interface for a previously developed automated SOFA score calculator. The final user interface usability was evaluated by clinician end users with the Computer Systems Usability Questionnaire. The overall mean (standard deviation, SD) time-to-complete manual SOFA score calculation time was 61.6 s (33). Among the 24% (12/50) usability survey respondents, our user-centered user interface design process resulted in >75% favorability of survey items in the domains of system usability, information quality, and interface quality. Early stakeholder engagement in our agile design process resulted in a user interface for an automated SOFA score calculator that reduced clinician workload and met clinicians' needs at the point of care. Emerging interoperable platforms may facilitate dissemination of similarly useful clinical score calculators and decision support algorithms as "apps." A user-centered design process and usability evaluation should be considered during creation of these tools. ©Christopher Ansel Aakre, Jaben E Kitson, Man Li, Vitaly Herasevich. Originally published in JMIR Human Factors (http://humanfactors.jmir.org), 18.05.2017.

  7. Analysis of cardiac interventricular septum motion in different respiratory states

    NASA Astrophysics Data System (ADS)

    Tautz, Lennart; Feng, Li; Otazo, Ricardo; Hennemuth, Anja; Axel, Leon

    2016-03-01

    The interaction between the left and right heart ventricles (LV and RV) depends on load and pressure conditions that are affected by cardiac contraction and respiration cycles. A novel MRI sequence, XD-GRASP, allows the acquisition of multi-dimensional, respiration-sorted and cardiac-synchronized free-breathing image data. In these data, effects of the cardiac and respiratory cycles on the LV/RV interaction can be observed independently. To enable the analysis of such data, we developed a semi-automatic exploration workflow. After tracking a cross-sectional line positioned over the heart, over all motion states, the septum and heart wall border locations are detected by analyzing the grey-value profile under the lines. These data are used to quantify septum motion, both in absolute units and as a fraction of the heart size, to compare values for different subjects. In addition to conventional visualization techniques, we used color maps for intuitive exploration of the variable values for this multi-dimensional data set. We acquired short-axis image data of nine healthy volunteers, to analyze the position and the motion of the interventricular septum in different breathing states and different cardiac cycle phases. The results indicate a consistent range of normal septum motion values, and also suggest that respiratory phase-dependent septum motion is greatest near end-diastolic phases. These new methods are a promising tool to assess LV/RV ventricle interaction and the effects of respiration on this interaction.

  8. Self-Motion Perception and Motion Sickness

    NASA Technical Reports Server (NTRS)

    Fox, Robert A.

    1991-01-01

    Motion sickness typically is considered a bothersome artifact of exposure to passive motion in vehicles of conveyance. This condition seldom has significant impact on the health of individuals because it is of brief duration, it usually can be prevented by simply avoiding the eliciting condition and, when the conditions that produce it are unavoidable, sickness dissipates with continued exposure. The studies conducted examined several aspects of motion sickness in animal models. A principle objective of these studies was to investigate the neuroanatomy that is important in motion sickness with the objectives of examining both the utility of putative models and defining neural mechanisms that are important in motion sickness.

  9. Geometric effects resulting from the asymmetry of dipping fault: Hanging wall/ footwall effects

    NASA Astrophysics Data System (ADS)

    Wang, Dong; Xie, Li-Li; Hu, Jin-Jun

    2008-05-01

    Root-mean-square distance D rms with characteristic of weighted-average is introduced in this article firstly. D rms can be used to capture the general proximity of a site to a dipping fault plane comparing with the rupture distance D rup and the seismogenic distance D seis. Then, using D rup, D seis and D rms, the hanging wall/footwall effects on the peak ground acceleration (PGA) during the 1999 Chi-Chi earthquake are evaluated by regression analysis. The logarithm residual shows that the PGA on hanging wall is much greater than that on footwall at the same D rup or D seis when the D rup or D seis is used as site-to-source distance measure. In contrast, there is no significant difference between the PGA on hanging wall and that on footwall at the same D rms when D rms is used. This result confirms that the hanging wall/footwall effect is mainly a geometric effect caused by the asymmetry of dipping fault. Therefore, the hanging wall/footwall effect on the near-fault ground motions can be ignored in the future attenuation analysis if the root-mean-square distance D rms is used as the site-to-source distance measure.

  10. Diffusion of microspheres in shear flow near a wall: use to measure binding rates between attached molecules.

    PubMed Central

    Pierres, A; Benoliel, A M; Zhu, C; Bongrand, P

    2001-01-01

    The rate and distance-dependence of association between surface-attached molecules may be determined by monitoring the motion of receptor-bearing spheres along ligand-coated surfaces in a flow chamber (Pierres et al., Proc. Natl. Acad. Sci. U.S.A. 95:9256-9261, 1998). Particle arrests reveal bond formation, and the particle-to-surface distance may be estimated from the ratio between the velocity and the wall shear rate. However, several problems are raised. First, data interpretation requires extensive computer simulations. Second, the relevance of standard results from fluid mechanics to micrometer-size particles separated from surfaces by nanometer distances is not fully demonstrated. Third, the wall shear rate must be known with high accuracy. Here we present a simple derivation of an algorithm permitting one to simulate the motion of spheres near a plane in shear flow. We check that theoretical predictions are consistent with the experimental dependence of motion on medium viscosity or particle size, and the requirement for equilibrium particle height distribution to follow Boltzman's law. The determination of the statistical relationship between particle velocity and acceleration allows one to derive the wall shear rate with 1-s(-1) accuracy and the Hamaker constant of interaction between the particle and the wall with a sensitivity better than 10(-21) J. It is demonstrated that the correlation between particle height and mean velocity during a time interval Deltat is maximal when Deltat is about 0.1-0.2 s for a particle of 1.4-microm radius. When the particle-to-surface distance ranges between 10 and 40 nm, the particle height distribution may be obtained with a standard deviation ranging between 8 and 25 nm, provided the average velocity during a 160-ms period of time is determined with 10% accuracy. It is concluded that the flow chamber allows one to detect the formation of individual bonds with a minimal lifetime of 40 ms in presence of a disruptive force

  11. Motion versus fixed distraction of the joint in the treatment of ankle osteoarthritis: a prospective randomized controlled trial.

    PubMed

    Saltzman, Charles L; Hillis, Stephen L; Stolley, Mary P; Anderson, Donald D; Amendola, Annunziato

    2012-06-06

    Initial reports have shown the efficacy of fixed distraction for the treatment of ankle osteoarthritis. We hypothesized that allowing ankle motion during distraction would result in significant improvements in outcomes compared with distraction without ankle motion. We conducted a prospective randomized controlled trial comparing the outcomes for patients with advanced ankle osteoarthritis who were managed with anterior osteophyte removal and either (1) fixed ankle distraction or (2) ankle distraction permitting joint motion. Thirty-six patients were randomized to treatment with either fixed distraction or distraction with motion. The patients were followed for twenty-four months after frame removal. The Ankle Osteoarthritis Scale (AOS) was the main outcome variable. Two years after frame removal, subjects in both groups showed significant improvement compared with the status before treatment (p < 0.02 for both groups). The motion-distraction group had significantly better AOS scores than the fixed-distraction group at twenty-six, fifty-two, and 104 weeks after frame removal (p < 0.01 at each time point). At 104 weeks, the motion-distraction group had an overall mean improvement of 56.6% in the AOS score, whereas the fixed-distraction group had a mean improvement of 22.9% (p < 0.01). Distraction improved the patient-reported outcomes of treatment of ankle osteoarthritis. Adding ankle motion to distraction showed an early and sustained beneficial effect on outcome.

  12. Molecular Dynamics Study of Thermally Augmented Nanodroplet Motion on Chemical Energy Induced Wettability Gradient Surfaces.

    PubMed

    Chakraborty, Monojit; Chowdhury, Anamika; Bhusan, Richa; DasGupta, Sunando

    2015-10-20

    Droplet motion on a surface with chemical energy induced wettability gradient has been simulated using molecular dynamics (MD) simulation to highlight the underlying physics of molecular movement near the solid-liquid interface including the contact line friction. The simulations mimic experiments in a comprehensive manner wherein microsized droplets are propelled by the surface wettability gradient against forces opposed to motion. The liquid-wall Lennard-Jones interaction parameter and the substrate temperature are varied to explore their effects on the three-phase contact line friction coefficient. The contact line friction is observed to be a strong function of temperature at atomistic scales, confirming their experimentally observed inverse functionality. Additionally, the MD simulation results are successfully compared with those from an analytical model for self-propelled droplet motion on gradient surfaces.

  13. Influence of Joule heating on current-induced domain wall depinning

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moretti, Simone, E-mail: simone.moretti@usal.es; Raposo, Victor; Martinez, Eduardo

    2016-06-07

    The domain wall depinning from a notch in a Permalloy nanostrip on top of a SiO{sub 2}/Si substrate is studied theoretically under application of static magnetic fields and the injection of short current pulses. The influence of Joule heating on current-induced domain wall depinning is explored self-consistently by coupling the magnetization dynamics in the ferromagnetic strip to the heat transport throughout the system. Our results indicate that Joule heating plays a remarkable role in these processes, resulting in a reduction in the critical depinning field and/or in a temporary destruction of the ferromagnetic order for typically injected current pulses. Inmore » agreement with experimental observations, similar pinning-depinning phase diagrams can be deduced for both current polarities when the Joule heating is taken into account. These observations, which are incompatible with the sole contribution of spin transfer torques, provide a deeper understanding of the physics underlying these processes and establish the real scope of the spin transfer torque. They are also relevant for technological applications based on current-induced domain-wall motion along soft strips.« less

  14. The effect of wall geometry in particle-laden turbulent flow

    NASA Astrophysics Data System (ADS)

    Abdehkakha, Hoora; Iaccarino, Gianluca

    2016-11-01

    Particle-laden turbulent flow plays a significant role in various industrial applications, as turbulence alters the exchange of momentum and energy between particles and fluid flow. In wall-bounded flows, inhomogeneity in turbulent properties is the primary cause of turbophoresis that leads the particles toward the walls. Conversely, shear-induced lift force on the particles can become important if large scale vortical structures are present. The objective of this study is to understand the effects of geometry on fluid flows and consequently on particles transport and concentration. Direct numerical simulations combined with point particle Lagrangian tracking are performed for several geometries such as a pipe, channel, square duct, and squircle (rounded-corners duct). In non-circular ducts, anisotropic and inhomogeneous Reynolds stresses are the most influential phenomena that produce the secondary flows. It has been shown that these motions can have a significant impact on transporting momentum, vorticity, and energy from the core of the duct to the corners. The main focus of the present study is to explore the effects of near the wall structures and secondary flows on turbophoresis, lift, and particle concentration.

  15. Prognostic value of cardiac power output to left ventricular mass in patients with left ventricular dysfunction and dobutamine stress echo negative by wall motion criteria.

    PubMed

    Cortigiani, Lauro; Sorbo, Simone; Miccoli, Mario; Scali, Maria Chiara; Simioniuc, Anca; Morrone, Doralisa; Bovenzi, Francesco; Marzilli, Mario; Dini, Frank Lloyd

    2017-02-01

    Cardiac power output to left ventricular mass (power/mass) is an index of myocardial efficiency reflecting the rate at which cardiac work is delivered with respect to the potential energy stored in the left ventricular mass. In the present study, we sought to investigate the capability of power/mass assessed at peak of dobutamine stress echocardiography to predict mortality in patients with ischaemic cardiomyopathy and no inducible ischaemia. One-hundred eleven patients (95 males; age 68 ± 10 years) with 35 ± 7% mean left ventricular ejection fraction and a dobutamine stress echocardiography (up to 40 µg/kg/min) negative by wall motion criteria formed the study population. Power/mass at peak stress was obtained as the product of a constant (K = 2.22 × 10 -1 ) with cardiac output and the mean arterial pressure divided by left ventricular mass to convert the units to W/100 g. Patients were followed up for a median of 29 months (inter-quartile range 16-72 months). All-cause mortality was the only accepted clinical end point. Mean peak-stress power/mass was 0.70 ± 0.31 W/100 g. During follow-up, 29 deaths (26%) were registered. With a receiver operating characteristic analysis, a peak-stress power/mass ≤0.50 W/100 g [area under curve 0.72 (95% CI 0.63; 0.80), sensitivity 59%, specificity 80%] was the best value for predicting mortality. Univariate prognostic indicators were age, male sex, peak-stress ejection fraction, peak-stress stroke volume, peak-stress cardiac output, peak-stress cardiac power output ≤1.48 W, and peak-stress power/mass ≤0.50 W/100 g. At multivariate analysis, age (HR 1.08, 95% CI 1.04; 1.14; P = 0.004) and peak-stress power/mass ≤0.50 W/100 g (HR 4.05, 95% CI 1.36; 12.00; P = 0.01) provided independent prognostic information. Three-year mortality was 14% in patients with peak-stress power/mass >0.50 W/100 g and 47% in those with peak-stress power/mass ≤0.50 W/100 g (log-rank 20.4; P < 0.0001). Power/mass assessed at peak of

  16. Transverse beam motion on the second axis of the dual axis radiographic hydrodynamic test facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Caporaso, G J; Chen, Y J; Fawley, W M

    1999-03-23

    The accelerator on the second-axis of the Dual-Axis Radiographic Hydrodynamic Test (DARHT-II) facility will generate a 20 MeV, 2-4 kA, 2 µs long electron beam with an energy variation {<=} ± 0.5%. Four short current pulses with various lengths will be selected out of this 2 µs long current pulse and delivered to an x-ray converter target. The DARHT-II radiographic resolution requires these electron pulses to be focused to sub-millimeter spots on Bremsstrahlung targets with peak-to-peak transverse beam motion less than a few hundred microns. We have modeled the transverse beam motion, including the beam breakup instability, corkscrew motion, transversemore » resistive wall instability and beam induced transverse deflection in the kicker system, from the DARHT-II injector exit to the x-ray converter target. Simulations show that the transverse motion at the x-ray converters satisfies the DARHT-II radiographic requirements.« less

  17. Direct and Large Eddy Simulation of non-equilibrium wall-bounded turbulent flows

    NASA Astrophysics Data System (ADS)

    Park, Hee-Jun

    2005-11-01

    The performance of several existing SGS models in non-equilibrium wall-bounded turbulent flows is investigated through comparisons of LES and DNS. The test problem is a shear-driven three-dimensional turbulent channel flow at base Reτ˜210 established by impulsive motion of one of the channel walls in the spanwise direction with a spanwise velocity equal to 3/4 of the bulk mean velocity in the channel. The DNS and LES are performed using pseudo-spectral methods with resolutions of 128x128x129 and 32x64x65, respectively. The SGS models tested include the nonlinear Interactions Approximation model (NIA) [Haliloglu and Akhavan (2004)], the Dynamic Smagorinsky model (DSM) [Germano et al. (1991)], and the Dynamic Mixed Model (DMM) [Zang et al. (1993)]. The results show that NIA gives the best overall agreement with DNS. Both DMM and DSM over-predict the decay of the mean streamwise wall shear stress on the moving wall, while NIA gives results in close agreements with DNS. Similarly, NIA gives the best agreement with DNS in the prediction of the mean velocity, the higher-order turbulence statistics, and the lag angle between the mean shear and the turbulent shear stress. These results suggest that non-equilibrium wall-bounded turbulent flows can be accurately computed by LES with NIA as the SGS model.

  18. Virtual wall-based haptic-guided teleoperated surgical robotic system for single-port brain tumor removal surgery.

    PubMed

    Seung, Sungmin; Choi, Hongseok; Jang, Jongseong; Kim, Young Soo; Park, Jong-Oh; Park, Sukho; Ko, Seong Young

    2017-01-01

    This article presents a haptic-guided teleoperation for a tumor removal surgical robotic system, so-called a SIROMAN system. The system was developed in our previous work to make it possible to access tumor tissue, even those that seat deeply inside the brain, and to remove the tissue with full maneuverability. For a safe and accurate operation to remove only tumor tissue completely while minimizing damage to the normal tissue, a virtual wall-based haptic guidance together with a medical image-guided control is proposed and developed. The virtual wall is extracted from preoperative medical images, and the robot is controlled to restrict its motion within the virtual wall using haptic feedback. Coordinate transformation between sub-systems, a collision detection algorithm, and a haptic-guided teleoperation using a virtual wall are described in the context of using SIROMAN. A series of experiments using a simplified virtual wall are performed to evaluate the performance of virtual wall-based haptic-guided teleoperation. With haptic guidance, the accuracy of the robotic manipulator's trajectory is improved by 57% compared to one without. The tissue removal performance is also improved by 21% ( p < 0.05). The experiments show that virtual wall-based haptic guidance provides safer and more accurate tissue removal for single-port brain surgery.

  19. Identification and tracking of hairpin vortex auto-generation in turbulent wall-bounded flow

    NASA Astrophysics Data System (ADS)

    Huang, Yangzi; Green, Melissa

    2016-11-01

    Hairpin vortices have been widely accepted as component structures of turbulent boundary layers. Their properties (size, vorticity, energy) and dynamic phenomena (origin, growth, breakdown) have been shown to correlate to the complex, multi-scaled turbulent motions observed in both experiments and simulations. As established in the literature, the passage of a hairpin vortex creates a wall-normal ejection of fluid, which encounters the high-speed freestream resulting in near-wall shear and increased drag. A previously generated simulation of an isolated hairpin vortex is used to study the auto-generation of a secondary vortex structure. Eulerian methods such as the Q criterion and Γ2 function, as well as Lagrangian methods are used to visualize the three-dimensional hairpin vortices and the auto-generation process. The circulation development and wall-normal location of both primary and secondary hairpin heads are studied to determine if there is a correlation between the strength and height of the primary hairpin vortex with the secondary hairpin vortex auto-generation.

  20. Simple motion correction strategy reduces respiratory-induced motion artifacts for k-t accelerated and compressed-sensing cardiovascular magnetic resonance perfusion imaging.

    PubMed

    Zhou, Ruixi; Huang, Wei; Yang, Yang; Chen, Xiao; Weller, Daniel S; Kramer, Christopher M; Kozerke, Sebastian; Salerno, Michael

    2018-02-01

    Cardiovascular magnetic resonance (CMR) stress perfusion imaging provides important diagnostic and prognostic information in coronary artery disease (CAD). Current clinical sequences have limited temporal and/or spatial resolution, and incomplete heart coverage. Techniques such as k-t principal component analysis (PCA) or k-t sparcity and low rank structure (SLR), which rely on the high degree of spatiotemporal correlation in first-pass perfusion data, can significantly accelerate image acquisition mitigating these problems. However, in the presence of respiratory motion, these techniques can suffer from significant degradation of image quality. A number of techniques based on non-rigid registration have been developed. However, to first approximation, breathing motion predominantly results in rigid motion of the heart. To this end, a simple robust motion correction strategy is proposed for k-t accelerated and compressed sensing (CS) perfusion imaging. A simple respiratory motion compensation (MC) strategy for k-t accelerated and compressed-sensing CMR perfusion imaging to selectively correct respiratory motion of the heart was implemented based on linear k-space phase shifts derived from rigid motion registration of a region-of-interest (ROI) encompassing the heart. A variable density Poisson disk acquisition strategy was used to minimize coherent aliasing in the presence of respiratory motion, and images were reconstructed using k-t PCA and k-t SLR with or without motion correction. The strategy was evaluated in a CMR-extended cardiac torso digital (XCAT) phantom and in prospectively acquired first-pass perfusion studies in 12 subjects undergoing clinically ordered CMR studies. Phantom studies were assessed using the Structural Similarity Index (SSIM) and Root Mean Square Error (RMSE). In patient studies, image quality was scored in a blinded fashion by two experienced cardiologists. In the phantom experiments, images reconstructed with the MC strategy had higher

  1. Observations of the freeze/thaw performance of lithium fluoride by motion picture photography

    NASA Technical Reports Server (NTRS)

    Jaworske, D. A.; Perry, W. D.

    1991-01-01

    To gain direct observation of the molten salt phase change, a novel containerless technique was developed where the high surface tension of lithium fluoride was used to suspend a bead of the molten salt inside a specially designed wire cage. By varying the current passing through the wire, the cage also served as a variable heat source. In this way, the freeze/thaw performance of the lithium fluoride could be photographed by motion picture photography without the influence of container walls. The motion picture photography of the lithium fluoride sample revealed several zones during the phase change, a solid zone and a liquid zone, as expected, and a slush zone that was predicted by thermal analysis modeling.

  2. Magnet Fall inside a Conductive Pipe: Motion and the Role of the Pipe Wall Thickness

    ERIC Educational Resources Information Center

    Donoso, G.; Ladera, C. L.; Martin, P.

    2009-01-01

    Theoretical models and experimental results are presented for the retarded fall of a strong magnet inside a vertical conductive non-magnetic tube. Predictions and experimental results are in good agreement modelling the magnet as a simple magnetic dipole. The effect of varying the pipe wall thickness on the retarding magnetic drag is studied for…

  3. Spatial Distribution Measurement of Heart Wall Vibrations Generated by Remote Perturbation of Inner Pressure

    NASA Astrophysics Data System (ADS)

    Kanai, Hiroshi; Hasegawa, Hideyuki; Imamura, Kohsuke

    2006-05-01

    It is essential for the diagnosis of heart diseases to noninvasively measure instantaneous myocardial movability and transition properties during one cardiac cycle. This study proposes a novel method of noninvasively perturbing left ventricle (LV) internal pressure by remotely actuating the brachium artery with sinusoidal vibration for the diagnosis of myocardial movability. By attaching an actuator to the brachium artery and driving it with a sinusoidal wave of f0 Hz, the internal pressure of the artery is perturbed. The perturbation propagates along the artery to the LV of the heart and the sinusoidal perturbation of the LV internal pressure is induced. Using an ultrasound-based phased tracking method, the resultant minute motion of the heart wall can be noninvasively measured. Because the vibration mode of the heart wall depends on actuation frequency, by phantom experiments using a spherical shell made of silicone rubber, to which a silicone rubber tube is connected, the vibration mode was identified from the measurement of the spatial distribution of the motions by scanning with an ultrasonic beam. From an in vivo experiment, the principle of remote actuation was confirmed.

  4. Responses of a 58-story RC dual core shear wall and outrigger frame building inferred from two earthquakes

    USGS Publications Warehouse

    Çelebi, Mehmet

    2016-01-01

    Responses of a dual core shear-wall and outrigger-framed 58-story building recorded during the Mw6.0 Napa earthquake of 24 August 2014 and the Mw3.8 Berkeley earthquake of 20 October 2011 are used to identify its dynamic characteristics and behavior. Fundamental frequencies are 0.28 Hz (NS), 0.25 Hz (EW), and 0.43 Hz (torsional). Rigid body motions due to rocking are not significant. Average drift ratios are small. Outrigger frames do not affect average drift ratios or mode shapes. Local site effects do not affect the response; however, response associated with deeper structure may be substantial. A beating effect is observed from data of both earthquakes but beating periods are not consistent. Low critical damping ratios may have contributed to the beating effect. Torsion is relatively larger above outriggers as indicated by the time-histories of motions at the roof, possibly due to the discontinuity of the stiffer shear walls above level 47.

  5. Influence of Visual Motion, Suggestion, and Illusory Motion on Self-Motion Perception in the Horizontal Plane.

    PubMed

    Rosenblatt, Steven David; Crane, Benjamin Thomas

    2015-01-01

    A moving visual field can induce the feeling of self-motion or vection. Illusory motion from static repeated asymmetric patterns creates a compelling visual motion stimulus, but it is unclear if such illusory motion can induce a feeling of self-motion or alter self-motion perception. In these experiments, human subjects reported the perceived direction of self-motion for sway translation and yaw rotation at the end of a period of viewing set visual stimuli coordinated with varying inertial stimuli. This tested the hypothesis that illusory visual motion would influence self-motion perception in the horizontal plane. Trials were arranged into 5 blocks based on stimulus type: moving star field with yaw rotation, moving star field with sway translation, illusory motion with yaw, illusory motion with sway, and static arrows with sway. Static arrows were used to evaluate the effect of cognitive suggestion on self-motion perception. Each trial had a control condition; the illusory motion controls were altered versions of the experimental image, which removed the illusory motion effect. For the moving visual stimulus, controls were carried out in a dark room. With the arrow visual stimulus, controls were a gray screen. In blocks containing a visual stimulus there was an 8s viewing interval with the inertial stimulus occurring over the final 1s. This allowed measurement of the visual illusion perception using objective methods. When no visual stimulus was present, only the 1s motion stimulus was presented. Eight women and five men (mean age 37) participated. To assess for a shift in self-motion perception, the effect of each visual stimulus on the self-motion stimulus (cm/s) at which subjects were equally likely to report motion in either direction was measured. Significant effects were seen for moving star fields for both translation (p = 0.001) and rotation (p<0.001), and arrows (p = 0.02). For the visual motion stimuli, inertial motion perception was shifted in the

  6. Numerical Simulation of Dry Granular Flow Impacting a Rigid Wall Using the Discrete Element Method

    PubMed Central

    Wu, Fengyuan; Fan, Yunyun; Liang, Li; Wang, Chao

    2016-01-01

    This paper presents a clump model based on Discrete Element Method. The clump model was more close to the real particle than a spherical particle. Numerical simulations of several tests of dry granular flow impacting a rigid wall flowing in an inclined chute have been achieved. Five clump models with different sphericity have been used in the simulations. By comparing the simulation results with the experimental results of normal force on the rigid wall, a clump model with better sphericity was selected to complete the following numerical simulation analysis and discussion. The calculation results of normal force showed good agreement with the experimental results, which verify the effectiveness of the clump model. Then, total normal force and bending moment of the rigid wall and motion process of the granular flow were further analyzed. Finally, comparison analysis of the numerical simulations using the clump model with different grain composition was obtained. By observing normal force on the rigid wall and distribution of particle size at the front of the rigid wall at the final state, the effect of grain composition on the force of the rigid wall has been revealed. It mainly showed that, with the increase of the particle size, the peak force at the retaining wall also increase. The result can provide a basis for the research of relevant disaster and the design of protective structures. PMID:27513661

  7. Respiratory Motion-Resolved Compressed Sensing Reconstruction of Free-Breathing Radial Acquisition for Dynamic Liver MRI

    PubMed Central

    Chandarana, Hersh; Feng, Li; Ream, Justin; Wang, Annie; Babb, James S; Block, Kai Tobias; Sodickson, Daniel K; Otazo, Ricardo

    2015-01-01

    Purpose Demonstrate feasibility of free-breathing radial acquisition with respiratory motion-resolved compressed sensing (CS) reconstruction (XD-GRASP) for multiphase dynamic Gd-EOB-DTPA enhanced liver imaging, and compare image quality to CS reconstruction with respiratory motion-averaging (GRASP) and prior conventional breath-held Cartesian-sampled datasets (BH-VIBE) in same patients. Subjects and Methods In this HIPAA-compliant prospective study, 16 subjects underwent free-breathing continuous radial acquisition during Gd-EOB-DTPA injection, and had prior BH-VIBE exam available. Acquired data were reconstructed using motion-averaging GRASP approach, in which consecutive 84-spokes were grouped in each contrast-enhanced phase for a temporal resolution of ~14 seconds. Additionally, respiratory motion-resolved reconstruction was performed from the same k-space data, by sorting each contrast-enhanced phase into multiple respiratory motion states using compressed sensing algorithm named XD-GRASP, which exploits sparsity along both the contrast-enhancement and respiratory-state dimensions. Contrast-enhanced dynamic multi-phase XD-GRASP, GRASP, and BH-VIBE images were anonymized, pooled together in a random order and presented to two board-certified radiologists for independent evaluation of image quality, with higher score indicating more optimal exam. Results XD-GRASP reconstructions had significantly (all p<0.05) higher overall image quality scores compared to GRASP for early arterial (Reader 1: 4.3 ± 0.6 vs. 3.31 ± 0.6 ; Reader 2: 3.81 ± 0.8 vs. 3.38 ± 0.9) and late arterial (Reader 1: 4.5 ± 0.6 vs. 3.63 ± 0.6; Reader 2: 3.56 ± 0.5 vs. 2.88 ± 0.7) phases of enhancement for both readers. XD-GRASP also had higher overall image quality score in portal venous phase which was significant for Reader 1 (4.44 ± 0.5 vs. 3.75 ± 0.8; p=0.002). In addition, XD-GRASP had higher overall image quality score compared to BH-VIBE for early (Reader 1: 4.3±0.6 vs. 3.88±0

  8. Self-consistent simulations of a von Kármán type dynamo in a spherical domain with metallic walls.

    PubMed

    Guervilly, Céline; Brummell, Nicholas H

    2012-10-01

    We have performed numerical simulations of boundary-driven dynamos using a three-dimensional nonlinear magnetohydrodynamical model in a spherical shell geometry. A conducting fluid of magnetic Prandtl number Pm=0.01 is driven into motion by the counter-rotation of the two hemispheric walls. The resulting flow is of von Kármán type, consisting of a layer of zonal velocity close to the outer wall and a secondary meridional circulation. Above a certain forcing threshold, the mean flow is unstable to non-axisymmetric motions within an equatorial belt. For fixed forcing above this threshold, we have studied the dynamo properties of this flow. The presence of a conducting outer wall is essential to the existence of a dynamo at these parameters. We have therefore studied the effect of changing the material parameters of the wall (magnetic permeability, electrical conductivity, and thickness) on the dynamo. In common with previous studies, we find that dynamos are obtained only when either the conductivity or the permeability is sufficiently large. However, we find that the effect of these two parameters on the dynamo process are different and can even compete to the detriment of the dynamo. Our self-consistent approach allow us to analyze in detail the dynamo feedback loop. The dynamos we obtain are typically dominated by an axisymmetric toroidal magnetic field and an axial dipole component. We show that the ability of the outer shear layer to produce a strong toroidal field depends critically on the presence of a conducting outer wall, which shields the fluid from the vacuum outside. The generation of the axisymmetric poloidal field, on the other hand, occurs in the equatorial belt and does not depend on the wall properties.

  9. Compression of auditory space during forward self-motion.

    PubMed

    Teramoto, Wataru; Sakamoto, Shuichi; Furune, Fumimasa; Gyoba, Jiro; Suzuki, Yôiti

    2012-01-01

    Spatial inputs from the auditory periphery can be changed with movements of the head or whole body relative to the sound source. Nevertheless, humans can perceive a stable auditory environment and appropriately react to a sound source. This suggests that the inputs are reinterpreted in the brain, while being integrated with information on the movements. Little is known, however, about how these movements modulate auditory perceptual processing. Here, we investigate the effect of the linear acceleration on auditory space representation. Participants were passively transported forward/backward at constant accelerations using a robotic wheelchair. An array of loudspeakers was aligned parallel to the motion direction along a wall to the right of the listener. A short noise burst was presented during the self-motion from one of the loudspeakers when the listener's physical coronal plane reached the location of one of the speakers (null point). In Experiments 1 and 2, the participants indicated which direction the sound was presented, forward or backward relative to their subjective coronal plane. The results showed that the sound position aligned with the subjective coronal plane was displaced ahead of the null point only during forward self-motion and that the magnitude of the displacement increased with increasing the acceleration. Experiment 3 investigated the structure of the auditory space in the traveling direction during forward self-motion. The sounds were presented at various distances from the null point. The participants indicated the perceived sound location by pointing a rod. All the sounds that were actually located in the traveling direction were perceived as being biased towards the null point. These results suggest a distortion of the auditory space in the direction of movement during forward self-motion. The underlying mechanism might involve anticipatory spatial shifts in the auditory receptive field locations driven by afferent signals from

  10. Forward and backward motion of artificial helical swimmers in cylindrical channels

    NASA Astrophysics Data System (ADS)

    Acemoglu, Alperen; Temel, Fatma Zeynep; Yesilyurt, Serhat

    2013-11-01

    Motion of micro swimmers in confined geometries such as channels is important due to its relevance in in vivo medical applications such as minimally invasive surgery and drug delivery. Here, swimmers with diameters 0.8 mm and lengths 2 to 3 mm are produced with a 3D printer and cylindrical Nd2Fe14B magnets are placed inside the bodies. Rotating external magnetic field is used for the actuation of artificial swimmers. Different body and tail geometries are produced and experiments are conducted with a glycerol filled circular channel. Result demonstrate that decreasing channel diameter directly affects the forward motion of the swimmer due to the increasing drag. It is observed that step-out frequency, which defines maximum frequency at which the swimmer can establish a synchronous rotation with the external magnetic field, depends on the geometry of the swimmer and the channel diameter. There are significant differences between low and high frequency motion and forward and backward swimming. Longer tails enable higher forward velocities in high frequencies than backward ones, whereas forward and backward velocities are approximately the same at low frequencies. Furthermore backward motion is more stable than the forward one; at high frequencies, swimmers travel almost at the center of the channel for backward motion, and follow a helical trajectory near the wall during the forward motion. According to simulation results there is a flow which is induced by the rotation of the swimmer rotation that affects the swimmer's trajectory. We acknowledge the support from TUBITAK (Techonological & Research Council of Turkey) under the grant no: 111M376.

  11. Smooth- and rough-wall boundary layer structure from high spatial range particle image velocimetry

    NASA Astrophysics Data System (ADS)

    Squire, D. T.; Morrill-Winter, C.; Hutchins, N.; Marusic, I.; Schultz, M. P.; Klewicki, J. C.

    2016-10-01

    Two particle image velocimetry arrangements are used to make true spatial comparisons between smooth- and rough-wall boundary layers at high Reynolds numbers across a very wide range of streamwise scales. Together, the arrangements resolve scales ranging from motions on the order of the Kolmogorov microscale to those longer than twice the boundary layer thickness. The rough-wall experiments were obtained above a continuous sandpaper sheet, identical to that used by Squire et al. [J. Fluid Mech. 795, 210 (2016), 10.1017/jfm.2016.196], and cover a range of friction and equivalent sand-grain roughness Reynolds numbers (12 000 ≲δ+≲ 18000, 62 ≲ks+≲104 ). The smooth-wall experiments comprise new and previously published data spanning 6500 ≲δ+≲17 000 . Flow statistics from all experiments show similar Reynolds number trends and behaviors to recent, well-resolved hot-wire anemometry measurements above the same rough surface. Comparisons, at matched δ+, between smooth- and rough-wall two-point correlation maps and two-point magnitude-squared coherence maps demonstrate that spatially the outer region of the boundary layer is the same between the two flows. This is apparently true even at wall-normal locations where the total (inner-normalized) energy differs between the smooth and rough wall. Generally, the present results provide strong support for Townsend's [The Structure of Turbulent Shear Flow (Cambridge University Press, Cambridge, 1956), Vol. 1] wall-similarity hypothesis in high Reynolds number fully rough boundary layer flows.

  12. Application and assessment of a robust elastic motion correction algorithm to dynamic MRI.

    PubMed

    Herrmann, K-H; Wurdinger, S; Fischer, D R; Krumbein, I; Schmitt, M; Hermosillo, G; Chaudhuri, K; Krishnan, A; Salganicoff, M; Kaiser, W A; Reichenbach, J R

    2007-01-01

    The purpose of this study was to assess the performance of a new motion correction algorithm. Twenty-five dynamic MR mammography (MRM) data sets and 25 contrast-enhanced three-dimensional peripheral MR angiographic (MRA) data sets which were affected by patient motion of varying severeness were selected retrospectively from routine examinations. Anonymized data were registered by a new experimental elastic motion correction algorithm. The algorithm works by computing a similarity measure for the two volumes that takes into account expected signal changes due to the presence of a contrast agent while penalizing other signal changes caused by patient motion. A conjugate gradient method is used to find the best possible set of motion parameters that maximizes the similarity measures across the entire volume. Images before and after correction were visually evaluated and scored by experienced radiologists with respect to reduction of motion, improvement of image quality, disappearance of existing lesions or creation of artifactual lesions. It was found that the correction improves image quality (76% for MRM and 96% for MRA) and diagnosability (60% for MRM and 96% for MRA).

  13. Clinical validation of different echocardiographic motion pictures expert group-4 algorythms and compression levels for telemedicine.

    PubMed

    Barbier, Paolo; Alimento, Marina; Berna, Giovanni; Cavoretto, Dario; Celeste, Fabrizio; Muratori, Manuela; Guazzi, Maurizio D

    2004-01-01

    Tele-echocardiography is not widely used because of lengthy transmission times when using standard Motion Pictures Expert Groups (MPEG)-2 lossy compression algorythms, unless expensive high bandwidth lines are used. We sought to validate the newer MPEG-4 algorythms to allow further reduction in echocardiographic motion video file size. Four cardiologists expert in echocardiography read blindly 165 randomized uncompressed and compressed 2D and color Doppler normal and pathologic motion images. One Digital Video and 3 MPEG-4 compression algorythms were tested, the latter at 3 decreasing compression quality levels (100%, 65% and 40%). Mean diagnostic and image quality scores were computed for each file and compared across the 3 compression levels using uncompressed files as controls. File dimensions decreased from a range of uncompressed 12-83 MB to MPEG-4 0.03-2.3 MB. All algorythms showed mean scores that were not significantly different from uncompressed source, except the MPEG-4 DivX algorythm at the highest selected compression (40%, p=.002). These data support the use of MPEG-4 compression to reduce echocardiographic motion image size for transmission purposes, allowing cost reduction through use of low bandwidth lines.

  14. Dual-Gated Motion-Frozen Cardiac PET with Flurpiridaz F 18.

    PubMed

    Slomka, Piotr J; Rubeaux, Mathieu; Le Meunier, Ludovic; Dey, Damini; Lazewatsky, Joel L; Pan, Tinsu; Dweck, Marc R; Newby, David E; Germano, Guido; Berman, Daniel S

    2015-12-01

    A novel PET radiotracer, Flurpiridaz F 18, has undergone phase II clinical trial evaluation as a high-resolution PET cardiac perfusion imaging agent. In a subgroup of patients imaged with this agent, we assessed the feasibility and benefit of simultaneous correction of respiratory and cardiac motion. In 16 patients, PET imaging was performed on a 4-ring scanner in dual cardiac and respiratory gating mode. Four sets of data were reconstructed with high-definition reconstruction (HD•PET): ungated and 8-bin electrocardiography-gated images using 5-min acquisition, optimal respiratory gating (ORG)-as developed for oncologic imaging-using a narrow range of breathing amplitude around end-expiration level with 35% of the counts in a 7-min acquisition, and 4-bin respiration-gated and 8-bin electrocardiography-gated images (32 bins in total) using the 7-min acquisition (dual-gating, using all data). Motion-frozen (MF) registration algorithms were applied to electrocardiography-gated and dual-gated data, creating cardiac-MF and dual-MF images. We computed wall thickness, wall/cavity contrast, and contrast-to-noise ratio for standard, ORG, cardiac-MF, and dual-MF images to assess image quality. The wall/cavity contrast was similar for ungated (9.3 ± 2.9) and ORG (9.5 ± 3.2) images and improved for cardiac-MF (10.8 ± 3.6) and dual-MF images (14.8 ± 8.0) (P < 0.05). The contrast-to-noise ratio was 22.2 ± 9.1 with ungated, 24.7 ± 12.2 with ORG, 35.5 ± 12.8 with cardiac-MF, and 42.1 ± 13.2 with dual-MF images (all P < 0.05). The wall thickness was significantly decreased (P < 0.05) with dual-MF (11.6 ± 1.9 mm) compared with ungated (13.9 ± 2.8 mm), ORG (13.1 ± 2.9 mm), and cardiac-MF images (12.1 ± 2.7 mm). Dual (respiratory/cardiac)-gated perfusion imaging with Flurpiridaz F 18 is feasible and improves image resolution, contrast, and contrast-to-noise ratio when MF registration methods are applied. © 2015 by the Society of Nuclear Medicine and Molecular Imaging

  15. Fusion and erosion of cell walls during confugation in the fussion yeast (Schizosaccharomyces pombe).

    PubMed

    Calleja, G B; Yoo, B Y; Johnson, B F

    1977-06-01

    Conjugation in Schizosaccharomyces pombe was studied by transmission electron microscopy. Mural and nuclear events were scored from induction, the initial event, to meiosis I, the start of sporulation. These morphogenic markers were separately identifiable as flocculation, copulation, conjugation-tube formation, cross-wall formation, cross-wall erosion, conjugation-tube expansion, cytoplasmic fusion, de-differentiation of site of union, nuclear migration and karyogamy. The following were identified as new structural elements: sex hairs, which presumably mediate hydrogen bonding between cells during flocculation; crimp at the site of union; dark patch, which presumably serves as a leak-proof seal at the time of cross-wall erosion; suture, an electron-dense seam formed by the union of a copulant pair; and small electron-dense particles close to the site of wall erosion. No special structures on the cell wall could be identified as indicative of specific sites for potential copulatory activity. The discontinuity of the 2 cell walls at the site of union became so de-differentiated after fusion and erosion that it was no longer possible to pinpoint the site of union.

  16. Solid state engine with alternating motion

    DOEpatents

    Golestaneh, Ahmad A.

    1982-01-01

    Heat energy is converted to mechanical motion utilizing apparatus including a cylinder, a piston having openings therein reciprocable in the cylinder, inlet and outlet ports for warm water at one end of the cylinder, inlet and outlet ports for cool water at the other end of the cylinder, gates movable with the piston and slidably engaging the cylinder wall to alternately open and close the warm and cool water ports, a spring bearing against the warm water side of the piston and a double helix of a thermal shape memory material attached to the cool end of the cylinder and to the piston. The piston is caused to reciprocate by alternately admitting cool water and warm water to the cylinder.

  17. Solid state engine with alternating motion

    DOEpatents

    Golestaneh, A.A.

    1980-01-21

    Heat energy is converted to mechanical motion utilizing apparatus including a cylinder, a piston having openings therein reciprocable in the cylinder, inlet and outlet ports for warm water at one end of the cylinder, inlet and outlet ports for cool water at the other end of the cylinder, gates movable with the piston and slidably engaging the cylinder wall to alternately open and close the warm and cool water ports, a spring bearing against the warm water side of the piston and a double helix of a thermal shape memory material attached to the cool end of the cylinder and to the piston. The piston is caused to reciprocate by alternately admitting cool water and warm water to the cylinder.

  18. Bubble Motion through a Generalized Power-Law Fluid Flowing in a Vertical Tube

    PubMed Central

    Mukundakrishnan, Karthik; Eckmann, David M.; Ayyaswamy, P. S.

    2009-01-01

    Intravascular gas embolism may occur with decompression in space flight, as well as during cardiac and vascular surgery. Intravascular bubbles may be deposited into any end organ, such as the heart or the brain. Surface interactions between the bubble and the endothelial cells lining the vasculature result in serious impairment of blood flow and can lead to heart attack, stroke, or even death. To develop effective therapeutic strategies, there is a need for understanding the dynamics of bubble motion through blood and its interaction with the vessel wall through which it moves. Toward this goal, we numerically investigate the axisymmetric motion of a bubble moving through a vertical circular tube in a shear-thinning generalized power-law fluid, using a front-tracking method. The formulation is characterized by the inlet Reynolds number, capillary number, Weber number, and Froude number. The flow dynamics and the associated wall shear stresses are documented for a combination of two different inlet flow conditions (inlet Reynolds numbers) and three different effective bubble radii (ratio of the undeformed bubble radii to the tube radii). The results of the non-Newtonian model are then compared with that of the model assuming a Newtonian blood viscosity. Specifically, for an almost occluding bubble (effective bubble radius = 0.9), the wall shear stress and the bubble residence time are compared for both Newtonian and non-Newtonian cases. Results show that at low shear rates, for a given pressure gradient the residence time for a non-Newtonian flow is higher than that for a Newtonian flow. PMID:19426324

  19. Effect of interface deformability on thermocapillary motion of a drop in a tube

    NASA Astrophysics Data System (ADS)

    Mahesri, S.; Haj-Hariri, H.; Borhan, A.

    2014-03-01

    The effect of an externally imposed axial temperature gradient on the mobility and deformation of a drop in an otherwise stagnant liquid within an insulated cylindrical tube is investigated. In the absence of bulk transport of momentum and energy, the boundary integral technique is used to obtain the flow and temperature fields inside and outside the deformable drop. The steady drop shapes and the corresponding migration velocities are examined over a wide range of the dimensionless parameters. The steady drop shape is nearly spherical for dimensionless drop sizes <0.5, but becomes slightly elongated in the axial direction for drop sizes comparable to tube diameter. The adverse effect of drop deformation on the effective temperature gradient driving the motion is slightly more pronounced than its favorable effect of reducing drag, thereby leading to a slight reduction in drop mobility with increasing drop deformation. Increasing the viscosity ratio reduces drop deformation and leads to a slight enhancement in the relative mobility (with respect to free thermocapillary motion) of confined drops. When the drop fluid has a lower thermal conductivity than the exterior phase, the presence of the thermally-insulating wall increases the thermal driving force for drop motion (compared to that for the same drop in unbounded domain) by causing more pronounced bending of the isotherms toward the drop. However, the favorable thermal effect of the confining wall is overwhelmed by its retarding hydrodynamic effect, causing the confined drop to always move slower than its unbounded counterpart regardless of the value of the thermal conductivity ratio.

  20. Self Motion Perception and Motion Sickness

    NASA Technical Reports Server (NTRS)

    Fox, Robert A. (Principal Investigator)

    1991-01-01

    The studies conducted in this research project examined several aspects of motion sickness in animal models. A principle objective of these studies was to investigate the neuroanatomy that is important in motion sickness with the objectives of examining both the utility of putative models and defining neural mechanisms that are important in motion sickness.

  1. Comparison of the effects of streptokinase and tissue plasminogen activator on regional wall motion after first myocardial infarction: analysis by the centerline method with correction for area at risk.

    PubMed

    Cross, D B; Ashton, N G; Norris, R M; White, H D

    1991-04-01

    In a trial of streptokinase versus recombinant tissue-type plasminogen activator (rt-PA) for a first myocardial infarction, 270 patients were randomized. Regional left ventricular function was assessed in 214 patients at 3 weeks. The infarct-related artery was the left anterior descending artery in 78 patients, the right coronary artery in 122 and a dominant left circumflex artery in 14. Analysis was by the centerline method with a novel correction for the area of myocardium at risk, whereby the search region was determined by the anatomic distribution of the infarct-related artery. Infarct-artery patency at 3 weeks was 73% in the streptokinase group and 71% in the rt-PA group. Global left ventricular function did not differ between the two groups. Mean chord motion (+/- SD) in the most hypokinetic half of the defined search region was similar in the streptokinase and rt-PA groups (-2.4 +/- 1.5 versus -2.3 +/- 1.3, p = 0.63). There were no differences in hyperkinesia of the noninfarct zone. Compared with conventional centerline analysis, regional wall motion in the defined area at risk was significantly more abnormal. The two methods correlated strongly, however (r = 0.99, p less than 0.0001), and both methods produced similar overall results. Patients with a patent infarct-related artery and those with an occluded artery at the time of catheterization had similar levels of global function (ejection fraction 58 +/- 12% versus 57 +/- 12%, p = 0.58).(ABSTRACT TRUNCATED AT 250 WORDS)

  2. Dynamic response of some tentative compliant wall structures to convected turbulence fields

    NASA Technical Reports Server (NTRS)

    Nijim, H. H.; Lin, Y. K.

    1977-01-01

    Some tentative compliant wall structures designed for possible skin friction drag reduction are investigated. Among the structural models considered is a ribbed membrane backed by polyurethane or PVS plastisol. This model is simplified as a beam placed on a viscoelastic foundation as well as on a set of evenly spaced supports. The total length of the beam may be either finite or infinite, and the supports may be either rigid or elastic. Another structural model considered is a membrane mounted over a series of pretensioned wires, also evenly spaced, and the entire membrane is backed by an air cavity. The forcing pressure field is idealized as a frozen random pattern convected downstream at a characteristic velocity. The results are given in terms of the frequency response functions of the system, the spectral density of the structural motion, and the spectral density of the boundary layer pressure including the effect of structural motion. These results are used in a parametric study of structural configurations capable of generating favorable wave lengths, wave amplitudes, and wave speeds in the structural motion for potential drag reduction.

  3. A New Wrist Clinical Evaluation Score.

    PubMed

    Herzberg, Guillaume; Burnier, Marion; Nakamura, Toshiyasu

    2018-04-01

    Background  The number of available wrist scoring systems is limited; some of them do not include forearm rotation criteria. Purpose  To describe a new electronic wrist clinical score and to present a new patient's generated wrist evaluation criterion, the subjective wrist value (SWV). Materials and Methods  A new electronic wrist clinical score, the Lyon wrist score (LWS) including wrist VAS pain and function, active range of motion and strength was built into an excel file. VAS flexion-extension pain and function were evaluated independently from pronation-supination pain and function. A new patient's generated wrist evaluation criterion, SWV was described. Results  The LWS is available in two versions, standard and full (the latter including forearm rotation strength). Both standard and full LWS are displayed into an automatically generated diamond-shaped graph providing a comprehensive visual display of the clinical status of most osteoarticular wrist disorders. The graph also includes SWV. The LWS, combined with SWV into a graph that may be directly exported to a PowerPoint presentation, provide a new practical and comprehensive tool for following/comparing wrist osteoarticular clinical status/outcomes. Both standard and full LWS charts are available in colored versions on a related website for free download. Conclusion  A comprehensive updated electronic display of osteoarticular wrist clinical status including forearm rotation criteria is provided and displayed into a graph which may be exported as such into a PowerPoint presentation for clinical analysis/comparisons. Level of Evidence  Level II.

  4. Enhancement of exchange bias in ferromagnetic/antiferromagnetic core-shell nanoparticles through ferromagnetic domain wall formation

    NASA Astrophysics Data System (ADS)

    Wu, Rui; Ding, Shilei; Lai, Youfang; Tian, Guang; Yang, Jinbo

    2018-01-01

    The spin configuration in the ferromagnetic part during the magnetization reversal plays a crucial role in the exchange bias effect. Through Monte Carlo simulation, the exchange bias effect in ferromagnetic-antiferromagnetic core-shell nanoparticles is investigated. Magnetization reversals in the ferromagnetic core were controlled between the coherent rotation and the domain wall motion by modulating the ferromagnetic domain wall width with parameters of uniaxial anisotropy constant and exchange coupling strength. An anomalous monotonic dependence of exchange bias on the uniaxial anisotropy constant is found in systems with small exchange coupling, showing an obvious violation of classic Meiklejohn-Bean model, while domain walls are found to form close to the interface and propagate in the ferromagnetic core with larger uniaxial anisotropy in both branches of the hysteresis. The asymmetric magnetization reversal with the formation of a spherical domain wall dramatically reduces the coercive field in the ascending branch, leading to the enhancement of the exchange bias. The results provide another degree of freedom to optimize the magnetic properties of magnetic nanoparticles for applications.

  5. Scaling and interaction of self-similar modes in models of high Reynolds number wall turbulence.

    PubMed

    Sharma, A S; Moarref, R; McKeon, B J

    2017-03-13

    Previous work has established the usefulness of the resolvent operator that maps the terms nonlinear in the turbulent fluctuations to the fluctuations themselves. Further work has described the self-similarity of the resolvent arising from that of the mean velocity profile. The orthogonal modes provided by the resolvent analysis describe the wall-normal coherence of the motions and inherit that self-similarity. In this contribution, we present the implications of this similarity for the nonlinear interaction between modes with different scales and wall-normal locations. By considering the nonlinear interactions between modes, it is shown that much of the turbulence scaling behaviour in the logarithmic region can be determined from a single arbitrarily chosen reference plane. Thus, the geometric scaling of the modes is impressed upon the nonlinear interaction between modes. Implications of these observations on the self-sustaining mechanisms of wall turbulence, modelling and simulation are outlined.This article is part of the themed issue 'Toward the development of high-fidelity models of wall turbulence at large Reynolds number'. © 2017 The Author(s).

  6. A pilot study on bladder wall thickness at different filling stages

    NASA Astrophysics Data System (ADS)

    Zhang, Xi; Liu, Yang; Li, Baojuan; Zhang, Guopeng; Liang, Zhengrong; Lu, Hongbing

    2015-03-01

    The ever-growing death rate and the high recurrence of bladder cancer make the early detection and appropriate followup procedure of bladder cancer attract more attention. Compare to optical cystoscopy, image-based studies have revealed its potentials in non-invasive observations of the abnormities of bladder recently, in which MR imaging turns out to be a better choice for bladder evaluation due to its non-ionizing and high contrast between urine and wall tissue. Recent studies indicate that bladder wall thickness tends to be a good indicator for detecting bladder wall abnormalities. However, it is difficult to quantitatively compare wall thickness of the same subject at different filling stages or among different subjects. In order to explore thickness variations at different bladder filling stages, in this study, we preliminarily investigate the relationship between bladder wall thickness and bladder volume based on a MRI database composed of 40 datasets acquired from 10 subjects at different filling stages, using a pipeline for thickness measurement and analysis proposed in our previous work. The Student's t-test indicated that there was no significant different on wall thickness between the male group and the female group. The Pearson correlation analysis result indicated that negative correlation with a correlation coefficient of -0.8517 existed between the wall thickness and bladder volume, and the correlation was significant(p <0.01). The corresponding linear regression equation was then estimated by the unary linear regression. Compared to the absolute value of wall thickness, the z-score of wall thickness would be more appropriate to reflect the thickness variations. For possible abnormality detection of a bladder based on wall thickness, the intra-subject and inter-subject thickness variation should be considered.

  7. Integrated evaluation of visually induced motion sickness in terms of autonomic nervous regulation.

    PubMed

    Kiryu, Tohru; Tada, Gen; Toyama, Hiroshi; Iijima, Atsuhiko

    2008-01-01

    To evaluate visually-induced motion sickness, we integrated subjective and objective responses in terms of autonomic nervous regulation. Twenty-seven subjects viewed a 2-min-long first-person-view video section five times (total 10 min) continuously. Measured biosignals, the RR interval, respiration, and blood pressure, were used to estimate the indices related to autonomic nervous activity (ANA). Then we determined the trigger points and some sensation sections based on the time-varying behavior of ANA-related indices. We found that there was a suitable combination of biosignals to present the symptoms of visually-induced motion sickness. Based on the suitable combination, integrating trigger points and subjective scores allowed us to represent the time-distribution of subjective responses during visual exposure, and helps us to understand what types of camera motions will cause visually-induced motion sickness.

  8. Being Moved by the Self and Others: Influence of Empathy on Self-Motion Perception

    PubMed Central

    Lopez, Christophe; Falconer, Caroline J.; Mast, Fred W.

    2013-01-01

    Background The observation of conspecifics influences our bodily perceptions and actions: Contagious yawning, contagious itching, or empathy for pain, are all examples of mechanisms based on resonance between our own body and others. While there is evidence for the involvement of the mirror neuron system in the processing of motor, auditory and tactile information, it has not yet been associated with the perception of self-motion. Methodology/Principal Findings We investigated whether viewing our own body, the body of another, and an object in motion influences self-motion perception. We found a visual-vestibular congruency effect for self-motion perception when observing self and object motion, and a reduction in this effect when observing someone else's body motion. The congruency effect was correlated with empathy scores, revealing the importance of empathy in mirroring mechanisms. Conclusions/Significance The data show that vestibular perception is modulated by agent-specific mirroring mechanisms. The observation of conspecifics in motion is an essential component of social life, and self-motion perception is crucial for the distinction between the self and the other. Finally, our results hint at the presence of a “vestibular mirror neuron system”. PMID:23326302

  9. Treatment of motion sickness in parabolic flight with buccal scopolamine

    NASA Technical Reports Server (NTRS)

    Norfleet, William T.; Degioanni, Joseph J.; Reschke, Millard F.; Bungo, Michael W.; Kutyna, Frank A.; Homick, Jerry L.; Calkins, D. S.

    1992-01-01

    Treatment of acute motion sickness induced by parabolic flight with a preparation of scopolamine placed in the buccal pouch was investigated. Twenty-one subjects flew aboard a KC-135 aircraft operated by NASA which performed parabolic maneuvers resulting in periods of 0-g, 1-g, and 1.8-g. Each subject flew once with a tablet containing scopolamine and once with a placebo in a random order, crossover design. Signs and symptoms of motion sickness were systematically recorded during each parabola by an investigator who was blind to the content of the tablet. Compared with flights using placebo, flights with buccal scopolamine resulted in significantly lower scores for nausea (31-35 percent reduction) and vomiting (50 percent reduction in number of parabolas with vomiting). Side effects of the drug during flight were negligible. It is concluded that buccal scopolamine is more effective than a placebo in treating ongoing motion sickness.

  10. Transient motion of mucus plugs in respiratory airways

    NASA Astrophysics Data System (ADS)

    Zamankhan, Parsa; Hu, Yingying; Helenbrook, Brian; Takayama, Shuichi; Grotberg, James B.

    2011-11-01

    Airway closure occurs in lung diseases such as asthma, cystic fibrosis, or emphysema which have an excess of mucus that forms plugs. The reopening process involves displacement of mucus plugs in the airways by the airflow of respiration. Mucus is a non-Newtonian fluid with a yield stress; therefore its behavior can be approximated by a Bingham fluid constitutive equation. In this work the reopening process is approximated by simulation of a transient Bingham fluid plug in a 2D channel. The governing equations are solved by an Arbitrary Lagrangian Eulerian (ALE) finite element method through an in-house code. The constitutive equation for the Bingham fluid is implemented through a regularization method. The effects of the yield stress on the flow features and wall stresses are discussed with applications to potential injuries to the airway epithelial cells which form the wall. The minimum driving pressure for the initiation of the motion is computed and its value is related to the mucus properties and the plug shape. Supported by HL84370 and HL85156.

  11. Subnanometer Motion of Cargoes Driven by Thermal Gradients Along Carbon Nanotubes

    NASA Astrophysics Data System (ADS)

    Barreiro, Amelia; Rurali, Riccardo; Hernández, Eduardo R.; Moser, Joel; Pichler, Thomas; Forró, László; Bachtold, Adrian

    2008-05-01

    An important issue in nanoelectromechanical systems is developing small electrically driven motors. We report on an artificial nanofabricated motor in which one short carbon nanotube moves relative to another coaxial nanotube. A cargo is attached to an ablated outer wall of a multiwalled carbon nanotube that can rotate and/or translate along the inner nanotube. The motion is actuated by imposing a thermal gradient along the nanotube, which allows for subnanometer displacements, as opposed to an electromigration or random walk effect.

  12. Associations between positive emotional well-being and stress-induced myocardial ischemia: Well-being scores predict exercise-induced ischemia.

    PubMed

    Feigal, Jacob P; Boyle, Stephen H; Samad, Zainab; Velazquez, Eric J; Wilson, Jennifer L; Becker, Richard C; Williams, Redford B; Kuhn, Cynthia M; Ortel, Thomas L; Rogers, Joseph G; O'Connor, Christopher M; Jiang, Wei

    2017-02-01

    Depressive symptoms have been associated with myocardial ischemia induced by mental (MSIMI) and exercise (ESIMI) stress in clinically stable ischemic heart disease (IHD) patients, but the association between positive emotions and inducible ischemia is less well characterized. The objective of this study was to examine the associations between ratings of well-being and stress-induced ischemia. Subjects were adult patients with documented IHD underwent mental and exercise stress testing for the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) trial. The General Well-Being Schedule (GWBS), with higher scores reflecting greater subjective well-being, and the Center for Epidemiologic Studies Depression Scale (CES-D) were obtained from the REMIT participants. Echocardiography was used to measure ischemic responses to mental stress and Bruce protocol treadmill exercise testing. Data were analyzed using logistic regression adjusting for age, sex, resting left-ventricular ejection fraction (LVEF), and resting wall motion score index, as well as health-related behaviors. GWBS scores were obtained for 210 individuals, with MSIMI present in 92 (43.8%) and ESIMI present in 64 (30.5%). There was a significant inverse correlation between GWBS-PE (Positive Emotion subscale) scores and probability of ESIMI (OR=0.55 (95%CI 0.36-0.83), p=0.005). This association persisted after additional control for CESD subscales measuring negative and positive emotions and for variables reflecting health-related behaviors. A similar inverse correlation between GWBS-PE and MSIMI was observed, but did not reach statistical significance (OR=0.81 (95%CI 0.54-1.20), p=0.28). This is, to our knowledge, the first study demonstrating that greater levels of self-reported positive emotions are associated with a lower likelihood of ESIMI among patients with known IHD. Our results highlight the important interface functions of the central nervous and cardiovascular systems and underscore

  13. Development of a rocking R/C shear wall system implementing repairable structural fuses

    NASA Astrophysics Data System (ADS)

    Parsafar, Saeed; Moghadam, Abdolreza S.

    2017-09-01

    In the last decades, the concept of earthquake resilient structural systems is becoming popular in which the rocking structure is considered as a viable option for buildings in regions of high seismicity. To this end, a novel wall-base connection based on the " repairable structure" approach is proposed and evaluated. The proposed system is made of several steel plates and high strength bolts act as a friction connection. To achieve the desired rocking motion in the proposed system, short-slotted holes are used in vertical directions for connecting the steel plates to the shear wall (SW). The experimental and numerical studies were performed using a series of displacement control quasi-static cyclic tests on a reference model and four different configurations of the proposed connection installed at the wall corners. The seismic response of the proposed system is compared to the conventional SW in terms of energy dissipation and damage accumulation. In terms of energy dissipation, the proposed system depicted better performance with 95% more energy dissipation capability compared to conventional SW. In terms of damage accumulation, the proposed SW system is nearly undamaged compared to the conventional wall system, which was severely damaged at the wall-base region. Overall, the introduced concept presents a feasible solution for R/C structures when a low-damage design is targeted, which can improve the seismic performance of the structural system significantly.

  14. Assessment of seismic design response factors of concrete wall buildings

    NASA Astrophysics Data System (ADS)

    Mwafy, Aman

    2011-03-01

    To verify the seismic design response factors of high-rise buildings, five reference structures, varying in height from 20- to 60-stories, were selected and designed according to modern design codes to represent a wide range of concrete wall structures. Verified fiber-based analytical models for inelastic simulation were developed, considering the geometric nonlinearity and material inelasticity of the structural members. The ground motion uncertainty was accounted for by employing 20 earthquake records representing two seismic scenarios, consistent with the latest understanding of the tectonic setting and seismicity of the selected reference region (UAE). A large number of Inelastic Pushover Analyses (IPAs) and Incremental Dynamic Collapse Analyses (IDCAs) were deployed for the reference structures to estimate the seismic design response factors. It is concluded that the factors adopted by the design code are adequately conservative. The results of this systematic assessment of seismic design response factors apply to a wide variety of contemporary concrete wall buildings with various characteristics.

  15. Extrinsic pinning of magnetic domain walls in CoFeB-MgO nanowires with perpendicular anisotropy

    NASA Astrophysics Data System (ADS)

    Zhang, Xueying; Vernier, Nicolas; Zhao, Weisheng; Vila, Laurent; Ravelosona, Dafiné

    2018-05-01

    In this work, we have studied the mechanism of domain wall motion in 0.2-1.5 μm wide nanowires based on Ta/CoFeB/MgO films with perpendicular magnetic anisotropy. We show that domain wall propagation can be completely stopped due to the presence of strong pinning sites along the nanowires. From the analysis of the distribution of the strongest depinning fields as a function of the wire width, we evidence the presence of extrinsic pinning sites in nanowires, probably induced by edge damages, that dominate over the intrinsic pinning of the magnetic films even for these large wire widths.

  16. Reinforcement mechanism of multi-anchor wall with double wall facing

    NASA Astrophysics Data System (ADS)

    Suzuki, Kouta; Kobayashi, Makoto; Miura, Kinya; Konami, Takeharu; Hayashi, Taketo

    2017-10-01

    The reinforced soil wall has high seismic performance as generally known. However, the seismic behavior has not been clarified accurately yet, especially on multi-anchor wall with double wall facing. Indefinite behavior of reinforced soil wall during earthquake make us complicated in case with adopting to the abutment, because of arrangement of anchor plate as reinforcement often different according to the width of roads. In this study, a series of centrifuge model tests were carried out to investigate the reinforcement mechanism of multi anchor wall with double wall facing from the perspective of the vertical earth pressure. Several types of reinforce arrangement and rigid wall were applied in order to verify the arch function in the reinforced regions. The test results show unique behavior of vertical earth pressure, which was affected by arch action. All the vertical earth pressure placed behind facing panel, are larger than that of middle part between facing panel despite of friction between backfill and facing panel. Similar results were obtained in case using rigid wall. On the other hands, the vertical earth pressure, which were measured at the 3cm high from bottom of model container, shows larger than that of bottom. This results show the existence of arch action between double walls. In addition, it implies that the wall facing of such soil structure confined the backfill as pseudo wall, which is very reason that the multi anchor wall with double wall facing has high seismic performance.

  17. MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis

    PubMed Central

    Szwedziak, Piotr; Wong, Felix; Schaefer, Kaitlin; Izoré, Thierry; Renner, Lars D; Holmes, Matthew J; Sun, Yingjie; Bisson-Filho, Alexandre W; Walker, Suzanne; Amir, Ariel; Löwe, Jan

    2018-01-01

    MreB is essential for rod shape in many bacteria. Membrane-associated MreB filaments move around the rod circumference, helping to insert cell wall in the radial direction to reinforce rod shape. To understand how oriented MreB motion arises, we altered the shape of Bacillus subtilis. MreB motion is isotropic in round cells, and orientation is restored when rod shape is externally imposed. Stationary filaments orient within protoplasts, and purified MreB tubulates liposomes in vitro, orienting within tubes. Together, this demonstrates MreB orients along the greatest principal membrane curvature, a conclusion supported with biophysical modeling. We observed that spherical cells regenerate into rods in a local, self-reinforcing manner: rapidly propagating rods emerge from small bulges, exhibiting oriented MreB motion. We propose that the coupling of MreB filament alignment to shape-reinforcing peptidoglycan synthesis creates a locally-acting, self-organizing mechanism allowing the rapid establishment and stable maintenance of emergent rod shape. PMID:29469806

  18. Current driven dynamics of magnetic domain walls in permalloy nanowires

    NASA Astrophysics Data System (ADS)

    Hayashi, Masamitsu

    The significant advances in micro-fabrication techniques opened the door to access interesting properties in solid state physics. With regard to magnetic materials, geometrical confinement of magnetic structures alters the defining parameters that govern magnetism. For example, development of single domain nano-pillars made from magnetic multilayers led to the discovery of electrical current controlled magnetization switching, which revealed the existence of spin transfer torque. Magnetic domain walls (DWs) are boundaries in magnetic materials that divide regions with distinct magnetization directions. DWs play an important role in the magnetization reversal processes of both bulk and thin film magnetic materials. The motion of DW is conventionally controlled by magnetic fields. Recently, it has been proposed that spin polarized current passed across the DW can also control the motion of DWs. Current in most magnetic materials is spin-polarized, due to spin-dependent scattering of the electrons, and thus can deliver spin angular momentum to the DW, providing a "spin transfer" torque on the DW which leads to DW motion. In addition, owing to the development of micro-fabrication techniques, geometrical confinement of magnetic materials enables creation and manipulation of a "single" DW in magnetic nanostructures. New paradigms for DW-based devices are made possible by the direct manipulation of DWs using spin polarized electrical current via spin transfer torque. This dissertation covers research on current induced DW motion in magnetic nanowires. Fascinating effects arising from the interplay between DWs with spin polarized current will be revealed.

  19. Algebraic motion of vertically displacing plasmas

    NASA Astrophysics Data System (ADS)

    Bhattacharjee, Amitava; Pfefferle, David; Hirvijoki, Eero

    2017-10-01

    The vertical displacement of tokamak plasmas is modelled during the non-linear phase by a free-moving current-carrying rod coupled to a set of fixed conducting wires and a cylindrical conducting shell. The models capture the leading term in a Taylor expansion of the Green's function for the interaction between the plasma column and the vacuum vessel. The plasma is assumed not to vary during the VDE such that it behaves as a rigid body. In the limit of perfectly conducting structures, the plasma is prevented from coming in contact with the wall due to steep effective potential barriers by the eddy currents, and will hence oscillate at Alfvénic frequencies about a given force-free position. In addition to damping oscillations, resistivity allows for the column to drift towards the vessel on slow flux penetration timescales. The initial exponential motion of the plasma, i.e. the resistive vertical instability, is succeeded by a non-linear sinking behaviour, that is shown analytically to be algebraic and decelerative. The acceleration of the plasma column often observed in experiments is thus conjectured to originate from an early sharing of toroidal current between the core, the halo plasma and the wall or from the thermal quench dynamics precipitating loss of plasma current

  20. Quality control of regional wall motion analysis in stress Echo 2020.

    PubMed

    Ciampi, Quirino; Picano, Eugenio; Paterni, Marco; Daros, Clarissa Borguezan; Simova, Iana; de Castro E Silva Pretto, José Luis; Scali, Maria Chiara; Gaibazzi, Nicola; Severino, Sergio; Djordjevic-Dikic, Ana; Kasprzak, Jaroslaw D; Zagatina, Angela; Varga, Albert; Lowenstein, Jorge; Merlo, Pablo Martin; Amor, Miguel; Celutkiene, Jelena; Perez, Julio E; Di Salvo, Giovanni; Galderisi, Maurizio; Mori, Fabio; Costantino, Marco Fabio; Massa, Laura; Dekleva, Milica; Chaves, Daniel Quesada; Trambaiolo, Paolo; Citro, Rodolfo; Colonna, Paolo; Rigo, Fausto; Torres, Marco A R; Monte, Ines; Stankovic, Ivan; Neskovic, Aleksander; Cortigiani, Lauro; Re, Federica; Dodi, Claudio; D'Andrea, Antonello; Villari, Bruno; Arystan, Ayana; De Nes, Michele; Carpeggiani, Clara

    2017-12-15

    The trial "Stress Echo (SE) 2020" evaluates novel applications of SE beyond coronary artery disease. The aim of the study was control quality and harmonize reading criteria. One reader from 78 centers of the SE 2020 network asked for credentials to read a set of 20 SE video-clips selected by the core lab. All aspiring centers met the pre-requisite of high-volume and the years of experience in SE ranged from 5 to 31years (mean value 18years). The diagnostic gold standard was a reading by the core lab. The a priori determined pass threshold was 18/20 (≥90%). Of the initial 78 who started, 57 completed the first attempt: individual readers' score on first attempt ranged from 07/20 to 20/20 (accuracy from 35% to 100%, mean 78.7±13%) and 44 readers passed it. There was a very poor correlation between years of experience and the reader's score on first attempt (r=-0.161, p=0.231). Of the 13 readers who failed the first attempt, 12 took it again after the web-based session and their accuracy improved (74% vs. 96%, p<0.001). The kappa inter-observer agreement before and after web-based training was 0.59 on first attempt and rose to 0.91 on the last attempt. In SE reading, the volume of activity or years of experience is not synonymous with diagnostic quality. Qualitative analysis and operator-dependence can become a limiting weakness in clinical practice, in the absence of strict pathways of learning, credentialing and audit. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Electromagnetic approaches to wall characterization, wall mitigation, and antenna design for through-the-wall radar systems

    NASA Astrophysics Data System (ADS)

    Thajudeen, Christopher

    Through-the-wall imaging (TWI) is a topic of current interest due to its wide range of public safety, law enforcement, and defense applications. Among the various available technologies such as, acoustic, thermal, and optical imaging, which can be employed to sense and image targets of interest, electromagnetic (EM) imaging, in the microwave frequency bands, is the most widely utilized technology and has been at the forefront of research in recent years. The primary objectives for any Through-the-Wall Radar Imaging (TWRI) system are to obtain a layout of the building and/or inner rooms, detect if there are targets of interest including humans or weapons, determine if there are countermeasures being employed to further obscure the contents of a building or room of interest, and finally to classify the detected targets. Unlike conventional radar scenarios, the presence of walls, made of common construction materials such as brick, drywall, plywood, cinder block, and solid concrete, adversely affects the ability of any conventional imaging technique to properly image targets enclosed within building structures as the propagation through the wall can induce shadowing effects on targets of interest which may result in image degradation, errors in target localization, and even complete target masking. For many applications of TWR systems, the wall ringing signals are strong enough to mask the returns from targets not located a sufficient distance behind the wall, beyond the distance of the wall ringing, and thus without proper wall mitigation, target detection becomes extremely difficult. The results presented in this thesis focus on the development of wall parameter estimation, and intra-wall and wall-type characterization techniques for use in both the time and frequency domains as well as analysis of these techniques under various real world scenarios such as reduced system bandwidth scenarios, various wall backing scenarios, the case of inhomogeneous walls, presence

  2. The Role of Motion Concepts in Understanding Non-Motion Concepts

    PubMed Central

    Khatin-Zadeh, Omid; Banaruee, Hassan; Khoshsima, Hooshang; Marmolejo-Ramos, Fernando

    2017-01-01

    This article discusses a specific type of metaphor in which an abstract non-motion domain is described in terms of a motion event. Abstract non-motion domains are inherently different from concrete motion domains. However, motion domains are used to describe abstract non-motion domains in many metaphors. Three main reasons are suggested for the suitability of motion events in such metaphorical descriptions. Firstly, motion events usually have high degrees of concreteness. Secondly, motion events are highly imageable. Thirdly, components of any motion event can be imagined almost simultaneously within a three-dimensional space. These three characteristics make motion events suitable domains for describing abstract non-motion domains, and facilitate the process of online comprehension throughout language processing. Extending the main point into the field of mathematics, this article discusses the process of transforming abstract mathematical problems into imageable geometric representations within the three-dimensional space. This strategy is widely used by mathematicians to solve highly abstract and complex problems. PMID:29240715

  3. Range of motion of diabetic frozen shoulder recovers to the contralateral level

    PubMed Central

    Vastamäki, Heidi; Ristolainen, Leena

    2016-01-01

    Objective To determine whether frozen shoulder heals equally well in patients with and without diabetes and whether dependency on insulin affects the outcome. Methods We retrospectively examined 178 patients with idiopathic frozen shoulder; 27 patients had diabetes. We evaluated range of motion, pain, and functional results. The mean follow-up was 9.7 years (SD, 7.1 years). Results In the presence of frozen shoulder, range of motion did not differ between patients with and without diabetes. At follow-up, range of motion in all directions of both the affected and unaffected shoulders of patients with diabetes was inferior to that of patients without diabetes. Among patients with diabetes, range of motion of the once-frozen shoulder reached the level of the unaffected shoulder. Patients with and without diabetes experienced similar pain except during exertion. The Constant–Murley score was not significantly different between the two groups, and insulin dependency did not lead to worse outcomes. Conclusion Frozen shoulder heals well in patients with diabetes. PMID:27856934

  4. The effect of mild motion sickness and sopite syndrome on multitasking cognitive performance.

    PubMed

    Matsangas, Panagiotis; McCauley, Michael E; Becker, William

    2014-09-01

    In this study, we investigated the effects of mild motion sickness and sopite syndrome on multitasking cognitive performance. Despite knowledge on general motion sickness, little is known about the effect of motion sickness and sopite syndrome on multitasking cognitive performance. Specifically, there is a gap in existing knowledge in the gray area of mild motion sickness. Fifty-one healthy individuals performed a multitasking battery. Three independent groups of participants were exposed to two experimental sessions. Two groups received motion only in the first or the second session, whereas the control group did not receive motion. Measurements of motion sickness, sopite syndrome, alertness, and performance were collected during the experiment Only during the second session, motion sickness and sopite syndrome had a significant negative association with cognitive performance. Significant performance differences between symptomatic and asymptomatic participants in the second session were identified in composite (9.43%), memory (31.7%), and arithmetic (14.7%) task scores. The results suggest that performance retention between sessions was not affected by mild motion sickness. Multitasking cognitive performance declined even when motion sickness and soporific symptoms were mild. The results also show an order effect. We postulate that the differential effect of session on the association between symptomatology and multitasking performance may be related to the attentional resources allocated to performing the multiple tasks. Results suggest an inverse relationship between motion sickness effects on performance and the cognitive effort focused on performing a task. Even mild motion sickness has potential implications for multitasking operational performance.

  5. Computational Motion Phantoms and Statistical Models of Respiratory Motion

    NASA Astrophysics Data System (ADS)

    Ehrhardt, Jan; Klinder, Tobias; Lorenz, Cristian

    Breathing motion is not a robust and 100 % reproducible process, and inter- and intra-fractional motion variations form an important problem in radiotherapy of the thorax and upper abdomen. A widespread consensus nowadays exists that it would be useful to use prior knowledge about respiratory organ motion and its variability to improve radiotherapy planning and treatment delivery. This chapter discusses two different approaches to model the variability of respiratory motion. In the first part, we review computational motion phantoms, i.e. computerized anatomical and physiological models. Computational phantoms are excellent tools to simulate and investigate the effects of organ motion in radiation therapy and to gain insight into methods for motion management. The second part of this chapter discusses statistical modeling techniques to describe the breathing motion and its variability in a population of 4D images. Population-based models can be generated from repeatedly acquired 4D images of the same patient (intra-patient models) and from 4D images of different patients (inter-patient models). The generation of those models is explained and possible applications of those models for motion prediction in radiotherapy are exemplified. Computational models of respiratory motion and motion variability have numerous applications in radiation therapy, e.g. to understand motion effects in simulation studies, to develop and evaluate treatment strategies or to introduce prior knowledge into the patient-specific treatment planning.

  6. Wearable PPG sensor based alertness scoring system.

    PubMed

    Dey, Jishnu; Bhowmik, Tanmoy; Sahoo, Saswata; Tiwari, Vijay Narayan

    2017-07-01

    Quantifying mental alertness in today's world is important as it enables the person to adopt lifestyle changes for better work efficiency. Miniaturized sensors in wearable devices have facilitated detection/monitoring of mental alertness. Photoplethysmography (PPG) sensors through Heart Rate Variability (HRV) offer one such opportunity by providing information about one's daily alertness levels without requiring any manual interference from the user. In this paper, a smartwatch based alertness estimation system is proposed. Data collected from PPG sensor of smartwatch is processed and fed to machine learning based model to get a continuous alertness score. Utility functions are designed based on statistical analysis to give a quality score on different stages of alertness such as awake, long sleep and short duration power nap. An intelligent data collection approach is proposed in collaboration with the motion sensor in the smartwatch to reduce battery drainage. Overall, our proposed wearable based system provides a detailed analysis of alertness over a period in a systematic and optimized manner. We were able to achieve an accuracy of 80.1% for sleep/awake classification along with alertness score. This opens up the possibility for quantifying alertness levels using a single PPG sensor for better management of health related activities including sleep.

  7. Relationship between selected orientation rest frame, circular vection and space motion sickness

    NASA Technical Reports Server (NTRS)

    Harm, D. L.; Parker, D. E.; Reschke, M. F.; Skinner, N. C.

    1998-01-01

    Space motion sickness (SMS) and spatial orientation and motion perception disturbances occur in 70-80% of astronauts. People select "rest frames" to create the subjective sense of spatial orientation. In microgravity, the astronaut's rest frame may be based on visual scene polarity cues and on the internal head and body z axis (vertical body axis). The data reported here address the following question: Can an astronaut's orientation rest frame be related and described by other variables including circular vection response latencies and space motion sickness? The astronaut's microgravity spatial orientation rest frames were determined from inflight and postflight verbal reports. Circular vection responses were elicited by rotating a virtual room continuously at 35 degrees/s in pitch, roll and yaw with respect to the astronaut. Latency to the onset of vection was recorded from the time the crew member opened their eyes to the onset of vection. The astronauts who used visual cues exhibited significantly shorter vection latencies than those who used internal z axis cues. A negative binomial regression model was used to represent the observed total SMS symptom scores for each subject for each flight day. Orientation reference type had a significant effect, resulting in an estimated three-fold increase in the expected motion sickness score on flight day 1 for astronauts who used visual cues. The results demonstrate meaningful classification of astronauts' rest frames and their relationships to sensitivity to circular vection and SMS. Thus, it may be possible to use vection latencies to predict SMS severity and duration.

  8. The clinical effect of rehabilitation following arthroscopic rotator cuff repair: A meta-analysis of early versus delayed passive motion.

    PubMed

    Li, Shuxiang; Sun, Han; Luo, Xiaomin; Wang, Kun; Wu, Guofeng; Zhou, Jian; Wang, Peng; Sun, Xiaoliang

    2018-01-01

    The argument on the recommended rehabilitation protocol following arthroscopic rotator cuff repair remains to be resolved. So this meta-analysis was presented to evaluate the differences of clinical effects between the 2 distinct rehabilitation protocols after arthroscopic rotator cuff repair. The PubMed, Cochrane Library, Web of Science, and EMBASE were systematically searched. Only randomized controlled trials (RCTs) published up to July 25, 2017, comparing early passive motion (EPM) versus delayed passive motion (DPM) rehabilitation protocols following arthroscopic rotator cuff repair were identified. The primary outcomes included range of motion and healing rate, while the secondary outcomes were Constant score, American Shoulder and Elbow Society (ASES) score, and Simple Shoulder Test (SST) score. The exclusion criteria contained biochemical trials, reviews, case reports, retrospective studies, without mention about passive motion exercise, no assessment of outcomes mentioned above, and no comparison of EPM and DPM rehabilitation protocols. Eight RCTs with 671 patients were enrolled in this study. The EPM resulted in improved shoulder forward flexion at short term, mid-term, and long-term follow-ups. The EPM group was superior to the DPM group in terms of external rotation (ER) at short-term and mid-term follow-ups. However, the DPM performed better long-term ASES score. These 2 protocols were equivalent in terms of ER at long term, ASES score at mid-term, SST score, Constant score, and healing rate. After excluding 2 RCTs that examined only small- and medium-sized tears, the pooled results of healing rate decreased from 82.4% to 76.6% in the EPM and 86.9% to 85.9% in the DPM. The meta-analysis suggests that the EPM protocol results in superior ROM recovery after arthroscopic rotator cuff repair but may adversely affect the shoulder function, which should be supported by further research. The healing rate at long-term follow-up is not clearly affected by the

  9. Average chest wall thickness at two anatomic locations in trauma patients.

    PubMed

    Schroeder, Elizabeth; Valdez, Carrie; Krauthamer, Andres; Khati, Nadia; Rasmus, Jessica; Amdur, Richard; Brindle, Kathleen; Sarani, Babak

    2013-09-01

    Needle thoracostomy is the emergent treatment for tension pneumothorax. This procedure is commonly done using a 4.5cm catheter, and the optimal site for chest wall puncture is controversial. We hypothesize that needle thoracostomy cannot be performed using this catheter length irrespective of the site chosen in either gender. A retrospective review of all chest computed tomography (CT) scans obtained on trauma patients from January 1, 2011 to December 31, 2011 was performed. Patients aged 18 and 80 years were included and patients whose chest wall thickness exceeded the boundary of the images acquired were excluded. Chest wall thickness was measured at the 2nd intercostal (ICS), midclavicular line (MCL) and the 5th ICS, anterior axillary line (AAL). Injury severity score (ISS), chest wall thickness, and body mass index (BMI) were analyzed. 201 patients were included, 54% male. Average (SD) BMI was 26 (7)kg/m(2). The average chest wall thickness in the overall cohort was 4.08 (1.4)cm at the 2nd ICS/MCL and 4.55 (1.7)cm at the 5th ICS/AAL. 29% of the overall cohort (27 male and 32 female) had a chest wall thickness greater than 4.5cm at the 2nd ICS/MCL and 45% (54 male and 36 female) had a chest wall thickness greater than 4.5cm at the 5th ICS/AAL. There was no significant interaction between gender and chest wall thickness at either site. BMI was positively associated with chest wall thickness at both the 2nd and 5th ICS/AAL. A 4.5cm catheter is inadequate for needle thoracostomy in most patients regardless of puncture site or gender. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Hyperecho PROPELLER-MRI: Application to rapid high-resolution motion-insensitive T2 -weighted black-blood imaging of the carotid arterial vessel wall and plaque.

    PubMed

    Yoneyama, Masami; Nakamura, Masanobu; Obara, Makoto; Okuaki, Tomoyuki; Sashi, Ryuji; Sawano, Seishi; Tatsuno, Satoshi; Van Cauteren, Marc

    2017-02-01

    To demonstrate the usefulness of hyperecho and PROPELLER (HEP) for carotid arterial vessel wall imaging by using a quantitative comparison with conventional methods. PROPELLER is a motion-insensitive turbo spin-echo (TSE) sequence and has recently been utilized in magnetic resonance (MR) plaque imaging instead of double inversion recovery TSE (DIR-TSE). Wider blade-width, higher k-space density, and an improved blood suppression effect result in better image quality. In this study we introduce a new combination of HEP. A total of 17 subjects were examined on a 3.0T system. We conducted quantitative comparisons for signal-to-noise ratio (SNR), contrast-to-noise-ratio, and image sharpness among HEP, DIR-TSE, and conventional PROPELLER (c-PROPELLER). Subsequently, images obtained with DIR-TSE, c-PROPELLER, and HEP were visually evaluated using a three-point scale by two board-certified radiologists. HEP showed high SNR similar to c-PROPELLER, good T 2 contrast approximating DIR-TSE, and better blood suppression compared with the other two methods (P < 0.05). The image sharpness of HEP (2.55 ± 0.53) was higher than that of DIR-TSE (1.89 ± 0.33) and the absence of ghost or streak artifacts in HEP (2.89 ± 0.33) was better than that in both other methods (2.22 ± 0.83 for DIR-TSE and 2.00 ± 0.50 for c-PROPELLER) (P < 0.05). Furthermore, the degree of blood suppression, particularly in cases of slow or turbulent flow close to the atherosclerotic plaque, was identical for HEP (2.80 ± 0.45) and DIR-TSE (2.80 ± 0.45) but was significantly better than for c-PROPELLER (1.60 ± 0.55) (P < 0.05). This study demonstrates the usefulness of HEP in the carotid arteries. HEP can provide higher-resolution T 2 -weighted black-blood imaging without flow- and/or motion-related artifacts, compared to conventional techniques. 3 J. Magn. Reson. Imaging 2017;45:515-524. © 2016 International Society for Magnetic Resonance in Medicine.

  11. Efficacy of early controlled motion of the ankle compared with no motion after non-operative treatment of an acute Achilles tendon rupture: study protocol for a randomized controlled trial.

    PubMed

    Barfod, Kristoffer Weisskirchner; Hansen, Maria Swennergren; Holmich, Per; Troelsen, Anders; Kristensen, Morten Tange

    2016-11-29

    Early controlled ankle motion is widely used in the non-operative treatment of acute Achilles tendon rupture, though its safety and efficacy have never been investigated in a randomized setup. The objectives of this study are to investigate if early controlled motion of the ankle affects functional and patient-reported outcomes. The study is performed as a blinded, randomized, controlled trial with patients allocated in a 1:1 ratio to one of two parallel groups. Patients aged from 18 to 70 years are eligible for inclusion. The intervention group performs early controlled motion of the ankle in weeks 3-8 after rupture. The control group is immobilized. In total, 130 patients will be included from one big orthopedic center over a period of 2½ years. The primary outcome is the patient-reported Achilles tendon Total Rupture Score evaluated at 12 months post-injury. Secondary outcome measures are the heel-rise work test, Achilles tendon elongation, and the rate of re-rupture. The primary analysis will be conducted as intention-to-treat analyses. This trial is the first to investigate the safety and efficacy of early controlled motion in the treatment of acute Achilles tendon rupture in a randomized setup. The study uses the patient-reported outcome measure, the Achilles tendon Total Rupture Score, as the primary endpoint, as it is believed to be the best surrogate measure for the tendon's actual capability to function in everyday life. ClinicalTrials.gov: NCT02015364 . Registered on 13 December 2013.

  12. Intelligent control of neurosurgical robot MM-3 using dynamic motion scaling.

    PubMed

    Ko, Sunho; Nakazawa, Atsushi; Kurose, Yusuke; Harada, Kanako; Mitsuishi, Mamoru; Sora, Shigeo; Shono, Naoyuki; Nakatomi, Hirofumi; Saito, Nobuhito; Morita, Akio

    2017-05-01

    OBJECTIVE Advanced and intelligent robotic control is necessary for neurosurgical robots, which require great accuracy and precision. In this article, the authors propose methods for dynamically and automatically controlling the motion-scaling ratio of a master-slave neurosurgical robotic system to reduce the task completion time. METHODS Three dynamic motion-scaling modes were proposed and compared with the conventional fixed motion-scaling mode. These 3 modes were defined as follows: 1) the distance between a target point and the tip of the slave manipulator, 2) the distance between the tips of the slave manipulators, and 3) the velocity of the master manipulator. Five test subjects, 2 of whom were neurosurgeons, sutured 0.3-mm artificial blood vessels using the MM-3 neurosurgical robot in each mode. RESULTS The task time, total path length, and helpfulness score were evaluated. Although no statistically significant differences were observed, the mode using the distance between the tips of the slave manipulators improves the suturing performance. CONCLUSIONS Dynamic motion scaling has great potential for the intelligent and accurate control of neurosurgical robots.

  13. Atypical anterior wall fracture of the acetabulum: case series of anterior acetabular rim fracture without involvement of the pelvic brim.

    PubMed

    Lenarz, Christopher J; Moed, Berton R

    2007-09-01

    The purpose of this study was to describe a form of anterior wall acetabular fracture, which has been inadequately defined in the literature. Retrospective analysis of consecutive patients. Level 1 trauma center. A retrospective analysis of consecutive acetabulum patients treated by a single surgeon between 1999 and 2005 identified 6 patients with a form of anterior wall fracture without involvement of the pelvic brim. All fractures were treated operatively. Open reduction and internal fixation through an anterior surgical approach. Final radiographic appearance and modified Merle d'Aubigne score. All 6 cases demonstrated characteristics of an atypical fracture of the anterior wall, involving the anterior rim of the acetabulum similar in nature to those described for the posterior wall, rather than the standard anterior wall fracture type described by Letournel. Of the 6 cases that were identified, 5 had follow-up 1 year or greater with a mean modified Merle d'Aubigne Score of 17 (range: 17-18). A form of anterior wall acetabular fracture exists, which involves the anterior acetabular rim without involvement of the pelvic brim. It can occur in young patients with high-energy mechanisms of injury, as well as in the elderly with low-energy trauma. With appropriate surgical management, using a modified Smith-Peterson approach, good to excellent clinical outcomes should be expected.

  14. Wind tunnels with adapted walls for reducing wall interference

    NASA Technical Reports Server (NTRS)

    Ganzer, U.

    1979-01-01

    The basic principle of adaptable wind tunnel walls is explained. First results of an investigation carried out at the Aero-Space Institute of Berlin Technical University are presented for two dimensional flexible walls and a NACA 0012 airfoil. With five examples exhibiting very different flow conditions it is demonstrated that it is possible to reduce wall interference and to avoid blockage at transonic speeds by wall adaptation.

  15. Inverse measurement of wall pressure field in flexible-wall wind tunnels using global wall deformation data

    NASA Astrophysics Data System (ADS)

    Brown, Kenneth; Brown, Julian; Patil, Mayuresh; Devenport, William

    2018-02-01

    The Kevlar-wall anechoic wind tunnel offers great value to the aeroacoustics research community, affording the capability to make simultaneous aeroacoustic and aerodynamic measurements. While the aeroacoustic potential of the Kevlar-wall test section is already being leveraged, the aerodynamic capability of these test sections is still to be fully realized. The flexibility of the Kevlar walls suggests the possibility that the internal test section flow may be characterized by precisely measuring small deflections of the flexible walls. Treating the Kevlar fabric walls as tensioned membranes with known pre-tension and material properties, an inverse stress problem arises where the pressure distribution over the wall is sought as a function of the measured wall deflection. Experimental wall deformations produced by the wind loading of an airfoil model are measured using digital image correlation and subsequently projected onto polynomial basis functions which have been formulated to mitigate the impact of measurement noise based on a finite-element study. Inserting analytic derivatives of the basis functions into the equilibrium relations for a membrane, full-field pressure distributions across the Kevlar walls are computed. These inversely calculated pressures, after being validated against an independent measurement technique, can then be integrated along the length of the test section to give the sectional lift of the airfoil. Notably, these first-time results are achieved with a non-contact technique and in an anechoic environment.

  16. Evaluating the Efficacy of an Animation to Enhance Understanding of First Motion Diagrams

    NASA Astrophysics Data System (ADS)

    Farmer, E. C.

    2011-12-01

    Having taught the interpretation of first motion diagrams (sometimes referred to as "beach ball diagrams" due to their appearance) in an Introduction to Physical Geology class over many semesters, I was frustrated with the hand-waving this effort entailed when describing static diagrams. I searched for a computer animation that would show how the initial ground motions in an earthquake correspond to the various shaded regions in each first motion diagram, but was not able to find such a pedagogical tool in existence. I decided to work with the staff of my University's Faculty Computing Services to create something that would serve this need. We designed and constructed an animation of strike-slip motions, which can be seen at http://people.hofstra.edu/alex_smiros/earthquake/grid_22march2011.swf. A still image of the animation appears in Figure 1. In order to see if utilizing this visualization enhanced student understanding of the difficult concepts involved in interpreting first motion diagrams, I compared scores on test questions involving first motion diagrams from two different semester iterations of the course: one was taught without utilizing the animation, and one was taught with utilization of the animation.

  17. Non-Debye domain-wall-induced dielectric response in Sr0.61-xCexBa0.39Nb2O6

    NASA Astrophysics Data System (ADS)

    Kleemann, W.; Dec, J.; Miga, S.; Woike, Th.; Pankrath, R.

    2002-06-01

    Two different non-Debye dielectric spectra are observed in a polydomain relaxor-ferroelectric Sr0.61-xBa0.39Nb2O6:Ce3+x single crystal in the vicinity of its transition temperature, Tc~320 K. At infralow frequencies the susceptibility varies as χ*~ω-β, β~0.2, and is attributed to an irreversible creep-like viscous motion of domain walls, while logarithmic dispersion due to reversible wall relaxation [T. Nattermann, Y. Shapir, and I. Vilfan, Phys. Rev. B 42, 8577 (1990)] occurs at larger ω.

  18. A novel VLES model accounting for near-wall turbulence: physical rationale and applications

    NASA Astrophysics Data System (ADS)

    Jakirlic, Suad; Chang, Chi-Yao; Kutej, Lukas; Tropea, Cameron

    2014-11-01

    A novel VLES (Very Large Eddy Simulation) model whose non-resolved residual turbulence is modelled by using an advanced near-wall eddy-viscosity model accounting for the near-wall Reynolds stress anisotropy influence on the turbulence viscosity by modelling appropriately the velocity scale in the relevant formulation (Hanjalic et al., 2004) is proposed. It represents a variable resolution Hybrid LES/RANS (Reynolds-Averaged Navier-Stokes) computational scheme enabling a seamless transition from RANS to LES depending on the ratio of the turbulent viscosities associated with the unresolved scales corresponding to the LES cut-off and the `unsteady' scales pertinent to the turbulent properties of the VLES residual motion, which varies within the flow domain. The VLES method is validated interactively in the process of the model derivation by computing fully-developed flow in a plane channel (important representative of wall-bounded flows, underlying the log-law for the velocity field, for studying near-wall Reynolds stress anisotropy) and a separating flow over a periodic arrangement of smoothly-contoured 2-D hills. The model performances are also assessed in capturing the natural decay of the homogeneous isotropic turbulence. The model is finally applied to swirling flow in a vortex tube, flow in an IC-engine configuration and flow past a realistic car model.

  19. [Temporal Analysis of Body Sway during Reciprocator Motion Movie Viewing].

    PubMed

    Sugiura, Akihiro; Tanaka, Kunihiko; Wakatabe, Shun; Matsumoto, Chika; Miyao, Masaru

    2016-01-01

    We aimed to investigate the effect of stereoscopic viewing and the degree of awareness of motion sickness on posture by measuring body sway during motion movie viewing. Nineteen students (12 men and 7 women; age range, 21-24 years) participated in this study. The movie, which showed several balls randomly positioned, was projected on a white wall 2 m in front of the subjects through a two-dimensional (2-D)/three-dimensional (3-D) convertible projector. To measure body sway during movie viewing, the subjects stood statically erect on a Wii balance board, with the toe opening at 18 degrees. The study protocol was as follows: The subjects watched (1) a nonmoving movie for 1 minute as the pretest and then (2) a round-trip sinusoidally moving-in-depth-direction movie for 3 minutes. (3) The initial static movie was shown again for 1 minute. Steps (2) and (3) were treated as one trial, after which two trials (2-D and 3-D movies) were performed in a random sequence. In this study, we found that posture changed according to the motion in the movie and that the longer the viewing time, the higher the synchronization accuracy. These tendencies depended on the level of awareness of motion sickness or the 3-D movie viewed. The mechanism of postural change in movie viewing was not vection but self-defense to resolve sensory conflict between visual information (spatial swing) and equilibrium sense (motionlessness).

  20. The Effects of Curriculum in Motion on Reading Scores for Male Students with Attention Deficit/Hyperactivity Disorder

    ERIC Educational Resources Information Center

    Pritchard, Jan Teena

    2013-01-01

    The most basic and fundamental skill for academic success is the ability to read. The purpose of this 1-group pretest and posttest pre-experimental quantitative study was to investigate how a unique instructional approach, called "curriculum in motion" with an emphasis on therapeutic martial arts and Brain Gym exercises influenced…

  1. Association Mapping of Cell Wall Synthesis Regulatory Genes and Cell Wall Quality in Switchgrass

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bartley, Laura; Wu, Y.; Zhu, L.

    . These markers might be used to select switchgrass genotypes with improved composition in breeding programs for biofuel and forage production. Because the SSAC continues to be characterized by collaborators in the bioenergy community, the data generated will be used to identify additional markers in higher resolution genotyping data to approach identifying the genes and alleles that cause natural variation in switchgrass cell wall quality. For example, these markers can be surveyed in the 2100-member Oklahoma Southern and Northern Lowland switchgrass collections that this project also characterized. An orthogonal approach to biodiversity studies, using comparative functional genomics permits systematic querying of how much regulatory information is likely to be transferable from dicots to grasses and use of accumulated functional genomics resources for better-characterized grass species, such as rice, itself a biomass source in global agriculture and in certain regions. The project generated and tested a number of specific hypotheses regarding cell wall transcription factors and enzymes of grasses. To aid identification of cell wall regulators, the project assembled a novel, highdepth and -quality gene association network using a general linearized model scoring system to combine rice gene network data. Using known or putative orthologs of Arabidopsis cell wall biosynthesis genes and regulators, the project pulled from this network a cell wall sub-network that includes 96 transcription factors. Reverse genetics of a co-ortholog of the Arabidopsis MYB61 transcription factor in rice revealed that this regulatory node has evolved the ability to regulate grass-specific cell wall synthesis enzymes. A transcription factor with such activity has not been previously characterized to our knowledge, representing a major conclusion of this work. Changes in gene expression in a protoplast-based assay demonstrated positive or negative roles in cell wall regulation for eleven other

  2. A Bio-Inspired, Motion-Based Analysis of Crowd Behavior Attributes Relevance to Motion Transparency, Velocity Gradients, and Motion Patterns

    PubMed Central

    Raudies, Florian; Neumann, Heiko

    2012-01-01

    The analysis of motion crowds is concerned with the detection of potential hazards for individuals of the crowd. Existing methods analyze the statistics of pixel motion to classify non-dangerous or dangerous behavior, to detect outlier motions, or to estimate the mean throughput of people for an image region. We suggest a biologically inspired model for the analysis of motion crowds that extracts motion features indicative for potential dangers in crowd behavior. Our model consists of stages for motion detection, integration, and pattern detection that model functions of the primate primary visual cortex area (V1), the middle temporal area (MT), and the medial superior temporal area (MST), respectively. This model allows for the processing of motion transparency, the appearance of multiple motions in the same visual region, in addition to processing opaque motion. We suggest that motion transparency helps to identify “danger zones” in motion crowds. For instance, motion transparency occurs in small exit passages during evacuation. However, motion transparency occurs also for non-dangerous crowd behavior when people move in opposite directions organized into separate lanes. Our analysis suggests: The combination of motion transparency and a slow motion speed can be used for labeling of candidate regions that contain dangerous behavior. In addition, locally detected decelerations or negative speed gradients of motions are a precursor of danger in crowd behavior as are globally detected motion patterns that show a contraction toward a single point. In sum, motion transparency, image speeds, motion patterns, and speed gradients extracted from visual motion in videos are important features to describe the behavioral state of a motion crowd. PMID:23300930

  3. Recovery after abdominal wall reconstruction.

    PubMed

    Jensen, Kristian Kiim

    2017-03-01

    implementation of the pathway. The enhanced recovery after surgery pathway included preoperative high-dose steroid, daily assessment of revised discharge criteria and an aggressive approach to restore bowel function (chewing gum and enema on postoperative day two). Patients who followed the enhanced recovery after surgery pathway reported low scores of pain, nausea and fatigue, and were discharged significantly faster than patients in the control group. A non-significant increase in postoperative readmissions and reoperations was observed after the introduction of the enhanced recovery after surgery pathway. Study III and IV were prospective studies of patients undergoing abdominal wall reconstruction for giant incisional hernia, who were compared to a control group of patients with an intact abdominal wall undergoing colorectal resection for benign or low-grade malignant disease. Patients were examined within a week preoperatively and again one year postoperatively. In study III, the respiratory function and respiratory quality of life were assessed, and the results showed that patients with a giant incisional hernia had a decreased expiratory lung function (peak expiratory flow and maximal expiratory pressure) compared to the predicted values and also compared to patients in the control group. Both parameters increased significantly after abdominal wall reconstruction, while no other significant changes were found in objective or subjective measures at one-year follow-up in both groups of patients. Lastly, study IV examined the abdominal wall- and extremity function, as well as overall and disease specific quality of life. We found that patients with a giant hernia had a significantly decreased relative function of the abdominal wall compared to patients with an intact abdominal wall, and that this deficit was offset at one-year follow-up. Patients in the control group showed a postoperative decrease in abdominal wall function, while no changes were found in extremity function

  4. Simultaneous measurement of instantaneous heart rate and chest wall plethysmography in short-term, metronome guided heart rate variability studies: suitability for assessment of autonomic dysfunction.

    PubMed

    Perring, S; Jones, E

    2003-08-01

    Instantaneous heart rate and chest wall motion were measured using a 3-lead ECG and an air pressure chest wall plethysmography system. Chest wall plethysmography traces were found to accurately represent the breathing pattern as measured by spirometry (average correlation coefficient 0.944); though no attempt was made to calibrate plethysmography voltage output to tidal volume. Simultaneous measurements of heart rate and chest wall motion were made for short periods under metronome guided breathing at 6 breaths per minute. The average peak to trough heart rate change per breath cycle (AVEMAX) and maximum correlation between heart rate and breathing cycle (HRBRCORR) were measured. Studies of 44 normal volunteers indicated clear inverse correlation of heart rate variability parameters with age (AVEMAX R = -0.502, P < 0.001) but no significant change in HRBRCORR with age (R = -0.115). Comparison of normal volunteers with diabetics with no history of symptoms associated with autonomic failure indicated significant lower heart rate variability in diabetics (P = 0.005 for AVEMAX) and significantly worse correlation between heart rate and breathing (P < 0.001 for HRBRCORR). Simultaneous measurement of heart rate and breathing offers the possibility of more sensitive diagnosis of autonomic failure in a simple bedside test and gives further insight into the nature of cardio-ventilatory coupling.

  5. Real-time ultrasound-tagging to track the 2D motion of the common carotid artery wall in vivo

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zahnd, Guillaume, E-mail: g.zahnd@erasmusmc.nl; Salles, Sébastien; Liebgott, Hervé

    2015-02-15

    Purpose: Tracking the motion of biological tissues represents an important issue in the field of medical ultrasound imaging. However, the longitudinal component of the motion (i.e., perpendicular to the beam axis) remains more challenging to extract due to the rather coarse resolution cell of ultrasound scanners along this direction. The aim of this study is to introduce a real-time beamforming strategy dedicated to acquire tagged images featuring a distinct pattern in the objective to ease the tracking. Methods: Under the conditions of the Fraunhofer approximation, a specific apodization function was applied to the received raw channel data, in real-time duringmore » image acquisition, in order to introduce a periodic oscillations pattern along the longitudinal direction of the radio frequency signal. Analytic signals were then extracted from the tagged images, and subpixel motion tracking of the intima–media complex was subsequently performed offline, by means of a previously introduced bidimensional analytic phase-based estimator. Results: The authors’ framework was applied in vivo on the common carotid artery from 20 young healthy volunteers and 6 elderly patients with high atherosclerosis risk. Cine-loops of tagged images were acquired during three cardiac cycles. Evaluated against reference trajectories manually generated by three experienced analysts, the mean absolute tracking error was 98 ± 84 μm and 55 ± 44 μm in the longitudinal and axial directions, respectively. These errors corresponded to 28% ± 23% and 13% ± 9% of the longitudinal and axial amplitude of the assessed motion, respectively. Conclusions: The proposed framework enables tagged ultrasound images of in vivo tissues to be acquired in real-time. Such unconventional beamforming strategy contributes to improve tracking accuracy and could potentially benefit to the interpretation and diagnosis of biomedical images.« less

  6. [Motion sickness in motion: from carsickness to cybersickness].

    PubMed

    Bos, J E; van Leeuwen, R B; Bruintjes, T D

    2018-01-01

    - Motion sickness is not a disorder, but a normal response to a non-normal situation in which movement plays a central role, such as car travel, sailing, flying, or virtual reality.- Almost anyone can suffer from motion sickness, as long as at least one of the organs of balance functions. If neither of the organs of balance functions the individual will not suffer from carsickness, seasickness, airsickness, nor from cybersickness. - 'Cybersickness' is a form of motion sickness that is stimulated by artificial moving images such as in videogames. Because we are now exposed more often and for longer periods of time to increasingly realistic artificial images, doctors will also encounter cases of motion sickness more often. - The basis for motion sickness is the vestibular system, which can be modulated by visual-vestibular conflicts, i.e. when the movements seen by the eyes are not the same as those experienced by the organs of balance.- Antihistamines can be effective against motion sickness in everyday situations such as car travel if taken before departure, but the effectiveness of medication for motion sickness is limited.

  7. A research on motion design for APP's loading pages based on time perception

    NASA Astrophysics Data System (ADS)

    Cao, Huai; Hu, Xiaoyun

    2018-04-01

    Due to restrictions caused by objective reasons like network bandwidth, hardware performance and etc., waiting is still an inevitable phenomenon that appears in our using mobile-terminal products. Relevant researches show that users' feelings in a waiting scenario can affect their evaluations on the whole product and services the product provides. With the development of user experience and inter-facial design subjects, the role of motion effect in the interface design has attracted more and more scholars' attention. In the current studies, the research theory of motion design in a waiting scenario is imperfect. This article will use the basic theory and experimental research methods of cognitive psychology to explore the motion design's impact on user's time perception when users are waiting for loading APP pages. Firstly, the article analyzes the factors that affect waiting experience of loading APP pages based on the theory of time perception, and then discusses motion design's impact on the level of time-perception when loading pages and its design strategy. Moreover, by the operation analysis of existing loading motion designs, the article classifies the existing loading motions and designs an experiment to verify the impact of different types of motions on the user's time perception. The result shows that the waiting time perception of mobile's terminals' APPs is related to the loading motion types, the combination type of loading motions can effectively shorten the waiting time perception as it scores a higher mean value in the length of time perception.

  8. Spontaneous Behaviors and Wall-Curvature Lead to Apparent Wall Preference in Planarian.

    PubMed

    Akiyama, Yoshitaro; Agata, Kiyokazu; Inoue, Takeshi

    2015-01-01

    The planarian Dugesia japonica tends to stay near the walls of its breeding containers and experimental dishes in the laboratory, a phenomenon called "wall preference". This behavior is thought to be important for environmental adaptation, such as hiding by planarians in nature. However, the mechanisms regulating wall-preference behavior are not well understood, since this behavior occurs in the absence of any particular stimulation. Here we show the mechanisms of wall-preference behavior. Surprisingly, planarian wall-preference behavior was also shown even by the head alone and by headless planarians. These results indicate that planarian "wall-preference" behavior only appears to be a "preference" behavior, and is actually an outcome of spontaneous behaviors, rather than of brain function. We found that in the absence of environmental cues planarians moved basically straight ahead until they reached a wall, and that after reaching a wall, they changed their direction of movement to one tangential to the wall, suggesting that this spontaneous behavior may play a critical role in the wall preference. When we tested another spontaneous behavior, the wigwag movement of the planarian head, using computer simulation with various wigwag angles and wigwag intervals, large wigwag angle and short wigwag interval reduced wall-preference behavior. This indicated that wigwag movement may determine the probability of staying near the wall or leaving the wall. Furthermore, in accord with this simulation, when we tested planarian wall-preference behavior using several assay fields with different curvature of the wall, we found that concavity and sharp curvature of walls negatively impacted wall preference by affecting the permissible angle of the wigwag movement. Together, these results indicate that planarian wall preference may be involuntarily caused by the combination of two spontaneous planarian behaviors: moving straight ahead until reaching a wall and then moving along it

  9. 41 CFR 60-30.8 - Motions; disposition of motions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the Administrative Law Judge. If made before or after the hearing itself, the motions shall be in writing. If made at the hearing, motions may be stated orally; but the Administrative Law Judge may... motion. Unless otherwise ordered by the Administrative Law Judge, written motions shall be accompanied by...

  10. 41 CFR 60-30.8 - Motions; disposition of motions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the Administrative Law Judge. If made before or after the hearing itself, the motions shall be in writing. If made at the hearing, motions may be stated orally; but the Administrative Law Judge may... motion. Unless otherwise ordered by the Administrative Law Judge, written motions shall be accompanied by...

  11. 41 CFR 60-30.8 - Motions; disposition of motions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the Administrative Law Judge. If made before or after the hearing itself, the motions shall be in writing. If made at the hearing, motions may be stated orally; but the Administrative Law Judge may... motion. Unless otherwise ordered by the Administrative Law Judge, written motions shall be accompanied by...

  12. 41 CFR 60-30.8 - Motions; disposition of motions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the Administrative Law Judge. If made before or after the hearing itself, the motions shall be in writing. If made at the hearing, motions may be stated orally; but the Administrative Law Judge may... motion. Unless otherwise ordered by the Administrative Law Judge, written motions shall be accompanied by...

  13. 41 CFR 60-30.8 - Motions; disposition of motions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the Administrative Law Judge. If made before or after the hearing itself, the motions shall be in writing. If made at the hearing, motions may be stated orally; but the Administrative Law Judge may... motion. Unless otherwise ordered by the Administrative Law Judge, written motions shall be accompanied by...

  14. Cyclic motion encoding for enhanced MR visualization of slip interfaces.

    PubMed

    Mariappan, Yogesh K; Glaser, Kevin J; Manduca, Armando; Ehman, Richard L

    2009-10-01

    To develop and test a magnetic resonance imaging-based method for assessing the mechanical shear connectivity across tissue interfaces with phantom experiments and in vivo feasibility studies. External vibrations were applied to phantoms and tissue and the differential motion on either side of interfaces within the media was mapped onto the phase of the MR images using cyclic motion encoding gradients. The phase variations within the voxels of functional slip interfaces reduced the net magnitude signal in those regions, thus enhancing their visualization. A simple two-compartment model was developed to relate this signal loss to the intravoxel phase variations. In vivo studies of the abdomen and forearm were performed to visualize slip interfaces in healthy volunteers. The phantom experiments demonstrated that the proposed technique can assess the functionality of shear slip interfaces and they provided experimental validation for the theoretical model developed. Studies of the abdomen showed that the slip interface between the small bowel and the peritoneal wall can be visualized. In the forearm, this technique was able to depict the slip interfaces between the functional compartments of the extrinsic forearm muscles. Functional shear slip interfaces can be visualized sensitively using cyclic motion encoding of externally applied tissue vibrations. (c) 2009 Wiley-Liss, Inc.

  15. Motion streaks in fast motion rivalry cause orientation-selective suppression.

    PubMed

    Apthorp, Deborah; Wenderoth, Peter; Alais, David

    2009-05-14

    We studied binocular rivalry between orthogonally translating arrays of random Gaussian blobs and measured the strength of rivalry suppression for static oriented probes. Suppression depth was quantified by expressing monocular probe thresholds during dominance relative to thresholds during suppression. Rivalry between two fast motions or two slow motions was compared in order to test the suggestion that fast-moving objects leave oriented "motion streaks" due to temporal integration (W. S. Geisler, 1999). If fast motions do produce motion streaks, then fast motion rivalry might also entail rivalry between the orthogonal streak orientations. We tested this using a static oriented probe that was aligned either parallel to the motion trajectory (hence collinear with the "streaks") or was orthogonal to the trajectory, predicting that rivalry suppression would be greater for parallel probes, and only for rivalry between fast motions. Results confirmed that suppression depth did depend on probe orientation for fast motion but not for slow motion. Further experiments showed that threshold elevations for the oriented probe during suppression exhibited clear orientation tuning. However, orientation-tuned elevations were also present during dominance, suggesting within-channel masking as the basis of the extra-deep suppression. In sum, the presence of orientation-dependent suppression in fast motion rivalry is consistent with the "motion streaks" hypothesis.

  16. A Five-Dimensional Mathematical Model for Regional and Global Changes in Cardiac Uptake and Motion

    NASA Astrophysics Data System (ADS)

    Pretorius, P. H.; King, M. A.; Gifford, H. C.

    2004-10-01

    The objective of this work was to simultaneously introduce known regional changes in contraction pattern and perfusion to the existing gated Mathematical Cardiac Torso (MCAT) phantom heart model. We derived a simple integral to calculate the fraction of the ellipsoidal volume that makes up the left ventricle (LV), taking into account the stationary apex and the moving base. After calculating the LV myocardium volume of the existing beating heart model, we employed the property of conservation of mass to manipulate the LV ejection fraction to values ranging between 13.5% and 68.9%. Multiple dynamic heart models that differ in degree of LV wall thickening, base-to-apex motion, and ejection fraction, are thus available for use with the existing MCAT methodology. To introduce more complex regional LV contraction and perfusion patterns, we used composites of dynamic heart models to create a central region with little or no motion or perfusion, surrounded by a region in which the motion and perfusion gradually reverts to normal. To illustrate this methodology, the following gated cardiac acquisitions for different clinical situations were simulated analytically: 1) reduced regional motion and perfusion; 2) same perfusion as in (1) without motion intervention; and 3) washout from the normal and diseased myocardial regions. Both motion and perfusion can change dynamically during a single rotation or multiple rotations of a simulated single-photon emission computed tomography acquisition system.

  17. Four-Dimensional Respiratory Motion-Resolved Whole Heart Coronary MR Angiography

    PubMed Central

    Piccini, Davide; Feng, Li; Bonanno, Gabriele; Coppo, Simone; Yerly, Jérôme; Lim, Ruth P.; Schwitter, Juerg; Sodickson, Daniel K.; Otazo, Ricardo; Stuber, Matthias

    2016-01-01

    Purpose Free-breathing whole-heart coronary MR angiography (MRA) commonly uses navigators to gate respiratory motion, resulting in lengthy and unpredictable acquisition times. Conversely, self-navigation has 100% scan efficiency, but requires motion correction over a broad range of respiratory displacements, which may introduce image artifacts. We propose replacing navigators and self-navigation with a respiratory motion-resolved reconstruction approach. Methods Using a respiratory signal extracted directly from the imaging data, individual signal-readouts are binned according to their respiratory states. The resultant series of undersampled images are reconstructed using an extradimensional golden-angle radial sparse parallel imaging (XD-GRASP) algorithm, which exploits sparsity along the respiratory dimension. Whole-heart coronary MRA was performed in 11 volunteers and four patients with the proposed methodology. Image quality was compared with that obtained with one-dimensional respiratory self-navigation. Results Respiratory-resolved reconstruction effectively suppressed respiratory motion artifacts. The quality score for XD-GRASP reconstructions was greater than or equal to self-navigation in 80/88 coronary segments, reaching diagnostic quality in 61/88 segments versus 41/88. Coronary sharpness and length were always superior for the respiratory-resolved datasets, reaching statistical significance (P < 0.05) in most cases. Conclusion XD-GRASP represents an attractive alternative for handling respiratory motion in free-breathing whole heart MRI and provides an effective alternative to self-navigation. PMID:27052418

  18. Wall shear stress characterization of a 3D bluff-body separated flow

    NASA Astrophysics Data System (ADS)

    Fourrié, Grégoire; Keirsbulck, Laurent; Labraga, Larbi

    2013-10-01

    Efficient flow control strategies aimed at reducing the aerodynamic drag of road vehicles require a detailed knowledge of the reference flow. In this work, the flow around the rear slanted window of a generic car model was experimentally studied through wall shear stress measurements using an electrochemical method. The mean and fluctuating wall shear stress within the wall impact regions of the recirculation bubble and the main longitudinal vortex structures which develop above the rear window are presented. Correlations allow a more detailed characterization of the recirculation phenomenon within the separation bubble. In the model symmetry plane the recirculation structure compares well with simpler 2D configurations; specific lengths, flapping motion and shedding of large-scale vortices are observed, these similarities diminish when leaving the middle plane due to the strong three-dimensionality of the flow. A specific attention is paid to the convection processes occurring within the recirculation: a downstream convection velocity is observed, in accordance with 2D recirculations from the literature, and an upstream convection is highlighted along the entire bubble length which has not been underlined in some previous canonical configurations.

  19. Designable and dynamic single-walled stiff nanotubes assembled from sequence-defined peptoids

    DOE PAGES

    Jin, Haibao; Ding, Yan-Huai; Wang, Mingming; ...

    2018-01-18

    Despite recent advances in assembly of organic nanotubes, conferral of sequence-defined engineering and dynamic response characteristics to the tubules remains a challenge. Here we report a new family of highly-designable and dynamic single-walled nanotubes assembled from sequence-defined peptoids through a unique “rolling-up and closure of nanosheet” mechanism. During the assembly process, amorphous spherical particles of amphiphilic peptoid oligomers (APOs) crystallized to form well-defined nanosheets which were then folded to form single-walled peptoid nanotubes (SW-PNTs). These SW-PNTs undergo a pH-triggered, reversible contraction-expansion motion. By varying the number of hydrophobic residues of APOs, we demonstrate the tuning of PNT wall thickness andmore » diameter, and mechanical properties. AFM-based mechanical measurements indicate that PNTs are highly stiff (Young’s Modulus ~13-17 GPa), comparable to the stiffest known biological materials. We further demonstrate that the precise incorporation of functional groups within PNTs and the application of functional PNTs in water decontamination. We believe these SW-PNTs can provide a robust platform for development of biomimetic materials tailored to specific applications.« less

  20. Designable and dynamic single-walled stiff nanotubes assembled from sequence-defined peptoids

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jin, Haibao; Ding, Yan-Huai; Wang, Mingming

    Despite recent advances in assembly of organic nanotubes, conferral of sequence-defined engineering and dynamic response characteristics to the tubules remains a challenge. Here we report a new family of highly-designable and dynamic single-walled nanotubes assembled from sequence-defined peptoids through a unique “rolling-up and closure of nanosheet” mechanism. During the assembly process, amorphous spherical particles of amphiphilic peptoid oligomers (APOs) crystallized to form well-defined nanosheets which were then folded to form single-walled peptoid nanotubes (SW-PNTs). These SW-PNTs undergo a pH-triggered, reversible contraction-expansion motion. By varying the number of hydrophobic residues of APOs, we demonstrate the tuning of PNT wall thickness andmore » diameter, and mechanical properties. AFM-based mechanical measurements indicate that PNTs are highly stiff (Young’s Modulus ~13-17 GPa), comparable to the stiffest known biological materials. We further demonstrate that the precise incorporation of functional groups within PNTs and the application of functional PNTs in water decontamination. We believe these SW-PNTs can provide a robust platform for development of biomimetic materials tailored to specific applications.« less