Sample records for war stability enhancing

  1. The Fatal Five? Five Factors That Enhance Effectiveness of Stability Operations

    DTIC Science & Technology

    2014-05-22

    Conflict METL Mission Essential Task List MSG Military Support Group NSS National Security Strategy OOTW Operations Other Than War PDF...Revolutionary War. However, despite the propensity for the military to conduct this type of operation, the U.S. Army has a mixed record of executing stability...the U.S. Army has a mixed record of executing stability tasks. This monograph identifies five factors that contribute to the effectiveness of

  2. Some lessons from NACA/NASA aerodynamic studies following World War II

    NASA Technical Reports Server (NTRS)

    Spearman, M. L.

    1983-01-01

    An historical account is presented of the new departures in aerodynamic research conducted by NACA, and subsequently NASA, as a result of novel aircraft technologies and operational regimes encountered in the course of the Second World War. The invention and initial development of the turbojet engine furnished the basis for a new speed/altitude regime in which numerous aerodynamic design problems arose. These included compressibility effects near the speed of sound, with attendant lift/drag efficiency reductions and longitudinal stability enhancements that were accompanied by a directional stability reduction. Major research initiatives were mounted in the investigation of swept, delta, trapezoidal and variable sweep wing configurations, sometimes conducted through flight testing of the 'X-series' aircraft. Attention is also given to the development of the first generation of supersonic fighter aircraft.

  3. Strengthening Strategic Stability with Russia

    DTIC Science & Technology

    2017-01-01

    war. Local conflicts, of course, need not escalate to general or nuclear war. Indeed, according to the stability - instability paradox, limited war...political stabil - ity. From the current Russian perspective, both of these compo- nents were thrown out of balance in the 1990s, creating instability ...part of the United States in the early 2000s, stra- tegic stability was replaced with instability and military-political defeats for Russia.27

  4. Department of Defense Chemical and Biological Defense Program. Annual Report to Congress

    DTIC Science & Technology

    2008-05-01

    defense system acquisition costs through collaboration in the areas of development, production , and support, and to enhance interoperability with...security area leverages S&T efforts of the other product areas. Where unmet requirements are identified and where S&T is required to meet cost ...Defense Program Inventory Requirements The industrial base, which has scaled down since the end of the Cold War, has stabilized. Ongoing military

  5. Blunting the Talons. The Impact of Peace Operations Deployments on USAF Fighter Crew Combat Skills

    DTIC Science & Technology

    1999-01-01

    Bomb Accuracy 74 Figure 5.16 - Typical Medium Altitude LGB Delivery 75 Figure 6.1 - Graph of Air-to-air Missile Shot Groups Showing Number of Shots...Between F-16C LGB and LALD/HD Practice Deliveries October 1997 Through February 1998 77 XI SUMMARY This document presents an analysis of the impact...intensive training promoted acted as a deterrent that reduced the chances war would occur - enhancing global stability. Thus, for the first 40

  6. The Impact on Strategic Stability of Ballistic Missile Defense in Eastern Europe

    DTIC Science & Technology

    2009-06-12

    how did we get to this point? And what does it mean for strategic stability? Is there even still such a thing in a post-Cold War and post-Anti...Despite these radical changes to global security since the end of the Cold War, very few examinations of exactly what strategic stability means ...examining the historical definition of the phrase and researching the various perturbations that have resulted from changing national nuclear capabilities

  7. The Causes and Dynamics of Conflict in Sub-Saharan Africa

    DTIC Science & Technology

    2009-05-10

    economic stability gained from two trends: the spread of constitutional democracy and economic globalization. Two major occurrences, colonialism and the Cold War, prevented the Sub-Saharan states from following these two trends. The disruption in sovereignty caused by colonialism, which was then followed by hastily formed governments during the Cold War, spawned conditions of corruption, scarcity, and violent competition. These conditions make it difficult for African states to achieve lasting stability and advance economically. As a result, any stability gained is often

  8. Translations on North Korea No. 601

    DTIC Science & Technology

    1978-07-13

    Boosting War Fever"] [Text] On 21 June, with the anniversary of the outbreak of the 24 June war just a few days away, the South Korean puppet clique...conducted the puppet farce of shooting matches between ministerial posts of the puppet adminis- tration, thus boosting war fever. At the war racket site...the puppet "prime minister" led the way in openly inciting war , raving about the "threat of southward aggression," the "nation’s stability" and the

  9. Stability and Antimicrobial Activity of Nisin-Loaded Mesoporous Silica Nanoparticles: A Game-Changer in the War against Maleficent Microbes.

    PubMed

    Behzadi, Faezeh; Darouie, Sheyda; Alavi, S Mehdi; Shariati, Parvin; Singh, Gurvinder; Dolatshahi-Pirouz, Alireza; Arpanaei, Ayyoob

    2018-04-25

    Antimicrobial agents, such as nisin, are used extensively in the food industry. Here, we investigated various approaches to load nisin onto mesoporous silica nanoparticles (MSNs, 92 ± 10 nm in diameter), to enhance its stability and sustained release. The morphology, size, and surface charge of the as-prepared nanoparticles were analyzed using scanning transmission electron microscopy, dynamic light scattering, and ζ potential measurement. Nisin was either physically adsorbed or covalently attached to the variously functionalized MSNs, with high loading capacities (>600 mg of nisin g -1 of nanoparticles). The results of antibacterial activity analysis of nisin against Staphylococcus aureus showed that, despite the very low antibacterial activity of nisin covalently conjugated onto MSNs, the physical adsorption of nisin onto the unfunctionalized nanoparticles enhances its antimicrobial activities under various conditions, with no significant cytotoxicity effects on mouse fibroblast L929 cells. In conclusion, MSNs can be recommended as suitable carriers for nisin under various conditions.

  10. American Influence on Post-World War I Recovery of Germany

    DTIC Science & Technology

    2015-06-12

    the world depended for its stability after the First World War. ― Robert Boyce, Paths to War: New Essays on the Origins of the Second World War...numerous committees involved in these plans. John Maynard Keynes wrote of his personal experience at the Paris Peace Conference where the Treaty of...Of future consequence, the Germans had imposed an armistice on Russia the previous December at Brest -Litovsk. The Russians were in no place to

  11. U.S. Department of Defense Official Website

    Science.gov Websites

    DefenseLink.mil Aug. 04, 2015 War on Terror Transformation News Products Press Resources Images Websites Contact presidential election expected to be a major stabilizing effort in a lynchpin country in the war on terror

  12. Stability Operations: From the Post-Vietnam War Era to Today

    DTIC Science & Technology

    2011-12-01

    Peacekeeping Doctrine, and Practice after the Cold War (Westport, CT: Praeger, 2004), 88. 14 John D. Waghelstein, “What’s Wrong in Iraq? Or Ruminations of a...stability operations. “I don’t think our troops ought to be used for what’s called nation-building,” Bush contended during the 2000 presidential...Waghelstein John D. “What’s Wrong in Iraq? Or Ruminations of a Pachyderm.” Military Review 86, no. 1 (January-February 2006). Warner, Volney J., and James H

  13. Strategic defense initiative: critical issues

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nuckolls, J.H.

    The objectives of the Strategic Defense Initiative (SDI) as outlined by President Reagan are discussed. The principal objective for SDI is as a defense against ballistic missiles. Soviet objections and a summary of US-USSR dialogue on the subject are reviewed. Most US studies have been critical of SDI. Four critical issues are addressed in depth: are defense weapons technologically feasible which have high economic leverage relative to offensive ballistic missiles; would the defense feasibility and leverage be degraded or enhanced in the technological race between weapons innovation and countermeasures; could stability be achieved during and after the transition to themore » defense dominated world envisioned by SDI proponents; would the deployment of high leverage defensive weapons increase or decrease the security of NATO Europe, and the probability of major conventional or nuclear wars. The issue of SDI may lead to a paradox that contains the seeds of catastrophe. The author concludes by warning that nuclear disarmament may eliminate the highly successful deterrent mechanism for avoiding another major world war. In a world made safe for major conventional wars by the apparent ''elimination'' of nuclear weapons, the leaders in a conventional World War III - involving unimaginable suffering, hatred, terror, and death - would be strongly motivated to introduce nuclear weapons in the crucial decisive battles. Even if diplomacy could ''eliminate'' nuclear weapons, man's knowledge of nuclear weapons can never be eliminated. The paradox is the attempt to eliminate nuclear weapons may maximize the probability of their use. (DMC)« less

  14. Army Medical Department Support to Stability Operations

    DTIC Science & Technology

    2007-02-28

    eliminate bubonic plague , vaccinate against smallpox, and institute measures for a safe water supply.21 Lieutenant General Arthur MacArthur, military...the war.36 Though the many medical assistance programs were plagued with unending challenges, and the overall outcome of the war has yet to be

  15. Medicolegal characteristics of firearm homicides in Belgrade, Serbia: before, during, and after the war in the Former Yugoslavia.

    PubMed

    Rancic, Nemanja; Erceg, Milena; Radojevic, Nemanja; Savic, Slobodan

    2013-11-01

    A comparative analysis of firearm homicides committed in Belgrade was performed including four representative years: 1987 (before the civil war in the Former Yugoslavia), 1991 (beginning of the war), 1997 (end of the war), and 2007 (period of social stabilization). The increase in the number of homicides was established in 1991 and 1997 compared with 1987, with the decrease in 2007, but with the continuous increase in the percentage of firearm homicides in the total number of homicides, from 12% in 1987 up to 56% in 2007. The significant increase in firearm homicides during the last decade of the 20th century can be explained by the social disturbances and the high availability of firearms, while their reduction in 2007 could be linked to the gradual stabilization of social circumstances. The results showed that the actual social, political, and economical changes strongly influenced medicolegal characteristics of homicides and particularly firearm homicides. © 2013 American Academy of Forensic Sciences.

  16. Planning and Assessing Stability Operations: A Proposed Value Focus Thinking Approach

    DTIC Science & Technology

    2007-03-01

    to avoid double -counting of possible consequences. 8... Taxes War Profiteering Arms Smuggling Grey Economy Avoidance of taxes Violation of regulations Smuggling Evasion of economic embargoes... Taxes War Profiteering Arms Smuggling Grey Economy Avoidance of taxes Violation of regulations Smuggling Evasion of economic embargoes

  17. Removal of cardiothoracic war-related shrapnel using video-assisted thoracoscopic surgery.

    PubMed

    Khalifa, Mohammed; Abu-Zidan, Fikri M; Khan, Navidul; Black, Edward

    2017-07-01

    This is the first report in the literature to describe removing war-related cardiothoracic shrapnel using video-assisted thoracoscopic surgery (VATS). War blast caused penetrating thoracic and extremity injuries in 30-year-old man. He was referred to our hospital after stabilization. Magnetic resonance imaging was required to evaluate brachial plexus injury. Large, penetrating shrapnel fragment in the right posterior chest wall, retained shrapnel in apex of the right lung, and another fragment in the pericardium were removed using VATS in staged approach. Postoperative period was uneventful. VATS is useful in managing complex, war-related cardiothoracic injuries.

  18. Congreve Rockets

    NASA Technical Reports Server (NTRS)

    2004-01-01

    The British fired Congreve rockets against the United States in the War of 1812. As a result Francis Scott Key coined the phrase the 'rocket's red glare.' Congreve had used a 16-foot guide stick to help stabilize his rocket. William Hale, another British inventor, invented the stickless rocket in 1846. The U.S. Army used the Hale rocket more than 100 years ago in the war with Mexico. Rockets were also used to a limited extent by both sides in the American Civil War.

  19. Early Rockets

    NASA Image and Video Library

    2004-04-15

    The British fired Congreve rockets against the United States in the War of 1812. As a result Francis Scott Key coined the phrase the "rocket's red glare." Congreve had used a 16-foot guide stick to help stabilize his rocket. William Hale, another British inventor, invented the stickless rocket in 1846. The U.S. Army used the Hale rocket more than 100 years ago in the war with Mexico. Rockets were also used to a limited extent by both sides in the American Civil War.

  20. Ballistic Missile Defense Deployment in Japan: Regional Reaction and the Future Stability of East Asia

    DTIC Science & Technology

    2004-01-01

    cited in Paine, The Sino-Japanese War of 1894-1895, 242. 9 Paine, 210. 10 J. Creelman , “The Massacre at Port Arthur,” The world (New York), 20 Dec...Manchuria during the Second Sino-Japanese War. The rape of Korea by the Japanese during this period was complete in physical , cultural...past. POST WORLD WAR II OCCUPATION The defeat of Japan in 1945 was total not only in terms of physical destruction of the country’s capacity

  1. The Families of U.S. Navy Prisoners of War from Vietnam Five Years after Reunion.

    ERIC Educational Resources Information Center

    Nice, D. Stephen; And Others

    1981-01-01

    Investigated marital stability and perceptions of marital adjustment and family environment among Navy prisoners of war repatriated from Vietnam (RPWs) and a Navy comparison group. Results indicated that the post-repatriation divorce rate among the RWP group was significantly higher than for the comparison group. (Author)

  2. Networks of military alliances, wars, and international trade

    PubMed Central

    Jackson, Matthew O.; Nei, Stephen

    2015-01-01

    We investigate the role of networks of alliances in preventing (multilateral) interstate wars. We first show that, in the absence of international trade, no network of alliances is peaceful and stable. We then show that international trade induces peaceful and stable networks: Trade increases the density of alliances so that countries are less vulnerable to attack and also reduces countries’ incentives to attack an ally. We present historical data on wars and trade showing that the dramatic drop in interstate wars since 1950 is paralleled by a densification and stabilization of trading relationships and alliances. Based on the model we also examine some specific relationships, finding that countries with high levels of trade with their allies are less likely to be involved in wars with any other countries (including allies and nonallies), and that an increase in trade between two countries correlates with a lower chance that they will go to war with each other. PMID:26668370

  3. Networks of military alliances, wars, and international trade.

    PubMed

    Jackson, Matthew O; Nei, Stephen

    2015-12-15

    We investigate the role of networks of alliances in preventing (multilateral) interstate wars. We first show that, in the absence of international trade, no network of alliances is peaceful and stable. We then show that international trade induces peaceful and stable networks: Trade increases the density of alliances so that countries are less vulnerable to attack and also reduces countries' incentives to attack an ally. We present historical data on wars and trade showing that the dramatic drop in interstate wars since 1950 is paralleled by a densification and stabilization of trading relationships and alliances. Based on the model we also examine some specific relationships, finding that countries with high levels of trade with their allies are less likely to be involved in wars with any other countries (including allies and nonallies), and that an increase in trade between two countries correlates with a lower chance that they will go to war with each other.

  4. More than War: Teachers' Stories from Israel and Northern Ireland

    ERIC Educational Resources Information Center

    Kendall, Stefanie Karin

    2010-01-01

    Increasingly, the effects of war--threat towards health, socio-economic stability, and social trust--are felt on the streets of cities and towns in conflict zones. Teachers in two locations, one a conflict zone, one post conflict, talk about the ways they respond to violent conflict in their community. Sderot, Israel, sits two kilometers from…

  5. ILE a Casualty of War

    DTIC Science & Technology

    2008-05-21

    field grade positions. Officer career progression to the field 68 Jamie Gayton, Force...to produce leaders for war. But the deferred cost of curtailing military education is very high.” - General J. Lawton Collins112 For many...Statistical data on ILE backlog by email 27 October 2007. Gayton, Jamie . “Force Stabilization.” Soldiers Magazine, June 2001 Hillen, John. "Must US

  6. Deterrence and Engagement: A Blended Strategic Approach to a Resurgent Russia

    DTIC Science & Technology

    2016-04-15

    Expansionism “If you know the enemy and know yourself, you need not fear the result of a hundred battles.” – Sun Tzu , The Art of War. An analysis...55 Bibliography ...the U.S. and its European allies, could achieve greater stability and security for Europe. 57 Bibliography Adamsky, Dmitry. “If War Comes

  7. Stability Operations: Policy and Doctrine Awaiting Implementation

    DTIC Science & Technology

    2013-03-01

    periods move through offense and defense (or reverse ) sequentially while stability is presented throughout the rotation. This causes stability to...The author’s personal experience in Afghanistan and having studied the complex nature of stability operations suggests the reverse is true. June...climate change, Euro/EU collapse, a democratic or collapsed China, a reformed Iran, nuclear war or WMD/cyber-attack, solar geomagnetic storms, U.S

  8. The principle of phase stability and the accelerator program at Berkeley, 1945--1954

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lofgren, E.J.

    1994-07-01

    The discovery of the Principle of Phase Stability by Vladimir Veksler and Edwin McMillian and the end of the war released a surge of accelerator activity at the Lawrence Berkeley Laboratory (then The University of California Radiation Laboratory). Six accelerators incorporating the Principle of Phase Stability were built in the period 1945--1954.

  9. British Military Mission (BMM) to Greece, 1942-44

    DTIC Science & Technology

    2009-05-21

    Terrorism. Failure to take into account and accurately assess political and military actions in such environments can lead to unintended consequences ...such environments can lead to unintended consequences (potential civil war) affecting the stability of a country. Accurate assessment of the political...take into account and accurately assess political and military actions in such environments can lead to unintended consequences (potential civil war

  10. Reconstruction versus Transformation: Post-War Education and the Struggle for Gender Equity in Sierra Leone

    ERIC Educational Resources Information Center

    Maclure, Richard; Denov, Myriam

    2009-01-01

    In post-war contexts, education is widely regarded as essential not only for civic reconciliation, but also as a key force for gender equity. In Sierra Leone, however, despite enhanced educational opportunities for girls, much of the emphasis on post-war educational reconstruction is unlikely to rectify gender inequities that remain entrenched…

  11. Association of Islamic Prayer with Psychological Stability in Bosnian War Veterans.

    PubMed

    Pajević, Izet; Sinanović, Osman; Hasanović, Mevludin

    2017-12-01

    To compare the outcomes among war veterans who pray/do not pray and who were not suffering mental disorders after the Bosnia-Herzegovina war (1992-95). The sample consists of 100 healthy Bosnian war veterans divided in two equal groups-one, a highly religious group inside which were individuals who perform five obligatory prayers every day, and another group of individuals who do not practice any daily prayer. We used Minnesota Multiphase Personal Inventory (MMPI), Profile Index of Emotions (PIE) and Life Style Questionnaire (LSQ). War veterans who prayed had significantly higher levels for: incorporation, self-protection, and for reactive formation; but significantly lower levels for regression, compensation, transfer, no-controlling, oppositional and aggressiveness than their peers who did not pray. Practicing religion (regular performing daily prayers) is associated with reduction of tendencies towards the tendency for risk, impulsiveness, and aggression. It is also associated with successful overcoming of emotional conflicts in war veterans who practiced religion than their peers who did not practice religion.

  12. Iraq: Post-Saddam Governance and Security

    DTIC Science & Technology

    2008-12-17

    Ottomans in World War I and took control of the territory in 1918 . Britain had tried to take Iraq from the Ottomans earlier in World War I but were...population. Sources: CIA The World Factbook; State Department International Religions Freedom Report, September 2008; DOD Measuring Stability...politically. Similarly, the September 19, 2008 report on International Religious Freedom attributed restrictions on the free exercise of religion (by

  13. Using the Arts to Teach Vietnam War Literature.

    ERIC Educational Resources Information Center

    Johannessen, Larry R.

    Starting a unit on Vietnam War literature by having students view slides of the Vietnam Veterans Memorial and listen to letters left there is just the first step in how an English teacher uses the arts to enhance student learning about the Vietnam War and its literature. After discussing their reactions to the slides and the offerings left at the…

  14. The War for Yemen

    DTIC Science & Technology

    2016-03-01

    coalition in Yemen with vital approaches that can speed recovery and stability. As Sun Tzu taught, we must know the enemy and know ourselves, and that...Iranian control, and work for stability in Yemen and use that as lessons for the region. AU/ACSC/J WATSON/AY16 17 Bibliography AlAhmad, Safa

  15. Afghanistan and Stability in Central Asia

    DTIC Science & Technology

    2009-03-23

    St ra te gy Re se ar ch Pr oj ec t AFGHANISTAN AND STABILITY IN CENTRAL ASIA BY LIEUTENANT COLONEL ABDULLAH HALIM Afghan Army U.S. Army War College...2. REPORT TYPE 3. DATES COVERED 4. TITLE AND SUBTITLE Afghanistan and Stability in Central Asia 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...STABILITY IN CENTRAL ASIA by Lieutenant Colonel Abdullah Halim Afghan Army Colonel David A. Kelley Project Adviser Only a work of the United States

  16. School of the Americas: At War With Democracy? Study Guide. Episode #804. America's Defense Monitor, Educational TV for the Classroom.

    ERIC Educational Resources Information Center

    Flaherty, Sean L.

    This program examines the 50-year practice of the U.S. training of Latin American soldiers at the School of the Americas. Originally designed as a jungle warfare training center in the 1950s, the program evolved into a Cold War program to promote stability and democracy in Latin America. Human rights abuses have been charged against these elite…

  17. Iraq: Post-Saddam Governance and Security

    DTIC Science & Technology

    2009-02-05

    defeated the Ottomans in World War I and took control of the territory in 1918 . Britain had tried to take Iraq from the Ottomans earlier in World War...World Factbook; State Department International Religions Freedom Report, September 2008; DOD Measuring Stability Report, December 2008; various press and...restrictions on the free exercise of religion (by religious minorities) to “terrorists, extremists, and criminal gangs,” while praising the Iraqi government

  18. Stability Operations in East Timor 1999-2000: A Case Study

    DTIC Science & Technology

    2016-04-11

    Institute April 11, 2016 Raymond A. Millen Senior Editor The views expressed in this report are those of the authors and do not necessarily reflect...Stability Operations Institute (PKSOI) publications enjoy full academic freedom, pro- vided they do not disclose classified information, jeopardize...to this report are invited and should be forwarded to: Director, Peacekeeping and Stability Operations Institute , U.S. Army War College, 22 Ashburn

  19. An Assessment of China’s Anti-Satellite and Space Warfare Programs, Policies and Doctrines

    DTIC Science & Technology

    2008-01-19

    selling their ballistic missile assets and space launch capabilities.” 14 8. According to Steven Lambakis, a 1994 U.S. Navy war game showed that China...of China conducted at the Naval War College in the spring of 1994. The war game , set in the year 2010, was a part of the Pentagon’s ongoing study of...enhance the effectiveness of their own forces. U.S. players in this war game were routed, their forces hit before they could throw up adequate defenses

  20. The Russian Federation Islamic Republic of Dagestan: Curricular Decentralization, Social Cohesion, and Stability

    ERIC Educational Resources Information Center

    Eaton, Jana Sackman

    2005-01-01

    This article focuses on the curricular decentralization-sociopolitical stability nexus in the predominantly Muslim Russian Federation Republic of Dagestan, adjacent to war-torn Chechnya. Concomitant with the metamorphoses taking place in the economic and political sectors of society is the overhaul of institutionalized education. A major reform…

  1. Stability Operations: Getting It Right in the Global War on Terrorism

    DTIC Science & Technology

    2005-03-18

    the United States of America (Washington, D.C.: The White House, September 2002), 1 " John Pike, "Where are the Legions? [ SPQR ] Global Deployments of...for a Postconflict Stability Force. Washington, D.C.: United States Institute of Peace Press, 2004. Pike, John. "Where Are the Legions? [ SPQR ] Global

  2. Harnessing Post-Conflict Transitions: A Conceptual Primer

    DTIC Science & Technology

    2010-09-01

    aid community uses transition as a key indi- cator of success for development and aid programs (Cliffe et al., 2003; Crane et al., 2009; Crichton ...3, pp. 345-365. Barnett, M ., (2006), “Building a republican peace: Stabilizing states after war,” International Security, Vol. 30, No. 4, pp. 87-112...Security, Vol. 29, No. 4, pp. 157-195. Berdal, M . R., (2009), Building Peace After War, Abingdon, UK; New York; London, UK: Routledge: International

  3. Ethiopian-Eritrean Conflict: Security Implications for the Horn of Africa

    DTIC Science & Technology

    2012-03-19

    and Eritrea accepted a diplomatic team from the United States and Rwanda to discuss and prevent the war from being pushed to its logical conclusion...2001), p. 6. 16 Medhane Tadesse ,The Djibouti-Eritrea Conflict, ( Inter Africa Group, Center for Dialogue on Humanitarian, Peace and Development...Tonui, Future Stability in the Horn of Africa, Strategy Research Project (U.S. Army War College, 2000), p. 18. 36 Medhane Tadesse ,The Djibouti

  4. Minerals Strategic Impact on Regional Stability in Africa

    DTIC Science & Technology

    2007-03-30

    very valuable. Diamonds are used primarily in one of two markets . One is the jewelry market and the other market is the industrial market . African...diamonds heading to the jewelry market were a central theme in two recent movies: The Lord of War and Blood Diamonds. In both movies, diamonds were...of the Master of Strategic Studies Degree. The U.S. Army War College is accredited by the Commission on Higher Education of the Middle States

  5. Gulf War Air Power Survey. Volume 5. A Statistical Compendium and Chronology

    DTIC Science & Technology

    1993-01-01

    documentation proved to be a blessing and a curse. While students and analysts of the Gulf War can tap an especially broad spectrum of information collected...to target folders and pre- and post-strike photos. They include interviews and oral history materials, SITREPS from several different Services and...these limits. You will note the first "day" lasted longer than one day and included two nights. Subsequently, the system stabilized according to a

  6. Ukraine: Current Issues and U.S. Policy

    DTIC Science & Technology

    2014-09-04

    received the first two tranches of the loan. Given the deterioration in the economy caused by the war , the IMF has agreed to combine the third and...shortcomings in the rule of law. The war has added to these problems, including the destruction of infrastructure in the Donbas and a steep drop in the...value of Ukraine’s currency. The Ukrainian government has received the first two installments of a $17 billion IMF loan designed to stabilize its

  7. Standardizing psycho-medical torture during the War on Terror: Why it happened, how it happened, and why it didn't work.

    PubMed

    Balfe, Myles

    2016-12-01

    After 9/11/2001 the United States launched a global War on Terror. As part of this War, terrorism suspects were detained by the U.S. military and by the C.I.A. It is now widely recognized that the United States tortured a number of these detainees in the context of its 'enhanced interrogation' programme. This article examines how and why U.S. organizations developed standards that allowed healthcare professionals to become involved in torture; why the standards developed by U.S. security institutions failed to control the actions of enhanced interrogation personnel on the ground; and what the role of standards were in stopping the enhanced interrogation initiative. The article concludes by discussing the general lessons that the enhanced interrogation programme has for social science research on standards, namely that individuals can experience ambivalence when caught between competing organizational and professional standards and that it might be inherently difficult to successfully enact certain protocols when these relate to deviant or destructive acts. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Star Wars?

    ERIC Educational Resources Information Center

    Berry, John

    1981-01-01

    Likening the relationship of the ALA and its professional divisions to that of the sun and its planets, this editorial explores the organizational characteristics and stability of the present system and solicits opinions. (RAA)

  9. The US Military’s Experience in Stability Operations, 1789-2005

    DTIC Science & Technology

    2006-01-01

    better trained in IO technical procedures than they were in how to produce a persuasive message . In the Dominican Republic in 1965, for example, the ...Yates, provides his thoughts and analysis of the US Army’s participation in stability operations (SO) since 1789. Dr. Yates, a member of the CSI Team...experience in the conduct of stability operations prior to the Global War on Terrorism can be divided chronologically into four periods: the country’s

  10. Religious Moral Beliefs Inversely Related to Trauma Experiences Severity and Presented Posttraumatic Stress Disorder Among Bosnia and Herzegovina War Veterans.

    PubMed

    Hasanović, Mevludin; Pajević, Izet

    2015-08-01

    The aim of this study was to determine the correlation of the level of religious moral beliefs (RMB) with trauma experiences and posttraumatic stress disorder (PTSD) severity in war veterans of Bosnia and Herzegovina. The sample consists of 120 Bosnian war veterans divided into two equal groups-one with and one without PTSD. We used the Harvard Trauma Questionnaire and the RMB belief scale. We then correlated the severity of trauma experiences and PTSD symptoms with veterans' scores on the RMB scale. The score on the RMB scale was negatively correlated to severity of trauma experiences and PTSD symptoms (Pearson's r = -0.509, P = 0.004; Pearson's r = -0.325, P < 0.001, respectively). The RMB may have protective role in the mental health stability of severely traumatized war veterans.

  11. Differential regulation of polarized synaptic vesicle trafficking and synapse stability in neural circuit rewiring in Caenorhabditis elegans

    PubMed Central

    Kurup, Naina; Kono, Karina

    2017-01-01

    Neural circuits are dynamic, with activity-dependent changes in synapse density and connectivity peaking during different phases of animal development. In C. elegans, young larvae form mature motor circuits through a dramatic switch in GABAergic neuron connectivity, by concomitant elimination of existing synapses and formation of new synapses that are maintained throughout adulthood. We have previously shown that an increase in microtubule dynamics during motor circuit rewiring facilitates new synapse formation. Here, we further investigate cellular control of circuit rewiring through the analysis of mutants obtained in a forward genetic screen. Using live imaging, we characterize novel mutations that alter cargo binding in the dynein motor complex and enhance anterograde synaptic vesicle movement during remodeling, providing in vivo evidence for the tug-of-war between kinesin and dynein in fast axonal transport. We also find that a casein kinase homolog, TTBK-3, inhibits stabilization of nascent synapses in their new locations, a previously unexplored facet of structural plasticity of synapses. Our study delineates temporally distinct signaling pathways that are required for effective neural circuit refinement. PMID:28636662

  12. War, Law and Order - Case Study: Australian Whole-of-Government Efforts to Develop the Security and Criminal Justice Sectors in Stabilization

    DTIC Science & Technology

    2012-05-01

    sought independence from Russia in 1991, resulting in a Russian military response and a brutal conflict that continues to this day. In the new...UN Secretary-General, Address to the UN Association of the UK, 31 January 2006, available at: http:// www.un.org/News/ossg/sg/ stories ... the Path to Victory, Centre for Strategic and International Studies, 27 July 2009. Cordesman, Anthony, ‘Sorry Story of Spin and lies in Afghan War

  13. Limited War Under the Nuclear Umbrella: An Analysis of India’s Cold Start Doctrine and Its Implications for Stability on the Subcontinent

    DTIC Science & Technology

    2010-06-01

    theory, by creating an offensive oriented 10 Tariq M. Ashraf , “Doctrinal Reawakening of the Indian...5Cpapers23%5Cpaper2293.html (accessed July 19, 2009). 19 Ashraf , “Doctrinal Reawakening,” 58. 10 nuclear threshold emerges as one of the major constraints...20 Ashraf , “Doctrinal Reawakening,” 59. 21 Ikram Sehgal, “War-Gaming Nuclear Armageddon,” The News, 29 January 2009

  14. Is the Botswana Defence Force Poised to Attain the Level of Military Effectiveness Espoused by Its Vision

    DTIC Science & Technology

    2014-02-13

    powerful adversaries in South Africa and Rhodesia . As southern Africa attained stability and endured the Cold War, there was rise in non-state actor...halt the acts of aggression from Rhodesia and South Africa 5 During wars of liberation, history attributes the country’s survival to the diplomatic...More than any other profession, military turns to history in much broader ways for reference and guidance.” 5 The Selous Scouts of Rhodesia

  15. United States Constabulary in Post-World War Two Germany: What Can Cowboys Tell Us About Stability Operations Today?

    DTIC Science & Technology

    2011-04-07

    Constabulary, colloquially known at the Circle C Cowboys for their distinct .unit insignia , provides lessons regarding the importance of specialized...fraternization with the German people. The goal of the directive was U.S. military governanc.e until local, n~ri- Nazi personnel could govern themselves. At the...end of the war and as the occupation began, insurrection from hard-line Nazis was the principal concern; however, it became evident that then~ were

  16. Crisis Stability and Long-Range Strike: A Comparative Analysis of Fighters, Bombers, and Missiles

    DTIC Science & Technology

    2013-01-01

    1947–1949 Crisis pakistan: Seize Kashmir hawker tempests , but not brandished or employed no India: Deny pakistan control of Kashmir hawker... tempests , but not brandished or employed no war Berlin 1948–1949 Crisis uSSR: Force western powers out of west Berlin Bombers and strike aircraft...resolution to border dispute B-24, B-57, hF-24, tempest , Mystère IV, Ouragan aircraft, but none brandished or employed no war Table C.1

  17. Planning for Action: Campaign Concepts and Tools

    DTIC Science & Technology

    2012-08-01

    142 10-15. Stability Mechanisms – Army .................................... 143 10-16. Stability Mechanisms – Joint...defeat mechanisms, which focus 143 the destructive and coercive capabilities of the force to provide security and public order and safety for...Matthew B. Ridgway. GEN Ridgway successfully led the 82d Airborne Division and XVIII Airborne Corps in the ETO during World War II and Eighth (US

  18. Educational Experiences and Mental Health among War-Zone Immigrants in Toronto

    ERIC Educational Resources Information Center

    Stermac, Lana; Brazeau, Paulette; Martin, Krystle

    2008-01-01

    Previous research suggested that educational engagement may enhance posttraumatic and post-migration adjustment and contribute to overall wellbeing among war-zone immigrants (Stermac et al., 2008). This study examined this further and compared the educational experiences and the health outcomes of immigrant students and non-students who had…

  19. Lions in the Path of Stability and Security: Oman’s Response to Pressing Issues in the Middle East

    DTIC Science & Technology

    2008-12-01

    brothers and sisters who have given their lives in service to their country - your love for your fellow man provides me eternal motivation, may you all...conditions of war. This thesis will explain how one little-known country in the heart of the region achieved a comfortable level of stability and...security. It will analyze Oman’s stability by explaining how the country has dealt with two sources of insecurity first an insurgency and then an

  20. Characterization of chemical warfare G-agent hydrolysis products by surface-enhanced Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Inscore, Frank E.; Gift, Alan D.; Maksymiuk, Paul; Farquharson, Stuart

    2004-12-01

    The United States and its allies have been increasingly challenged by terrorism, and since the September 11, 2001 attacks and the war in Afghanistan and Iraq, homeland security has become a national priority. The simplicity in manufacturing chemical warfare agents, the relatively low cost, and previous deployment raises public concern that they may also be used by terrorists or rogue nations. We have been investigating the ability of surface-enhanced Raman spectroscopy (SERS) to detect extremely low concentrations (e.g. part-per-billion) of chemical agents, as might be found in poisoned water. Since trace quantities of nerve agents can be hydrolyzed in the presence of water, we have expanded our studies to include such degradation products. Our SERS-active medium consists of silver or gold nanoparticles incorporated into a sol-gel matrix, which is immobilized in a glass capillary. The choice of sol-gel precursor allows controlling hydrophobicity, while the porous silica network offers a unique environment for stabilizing the SERS-active metals. Here we present the use of these metal-doped sol-gels to selectively enhance the Raman signal of the hydrolyzed products of the G-series nerve agents.

  1. The Calculus of War: The Role and Use of Quantitative Decision Aids at the Tactical Level of War

    DTIC Science & Technology

    1993-01-01

    significantly. Ceilings of unbroken clouds came down to only several hundred feet altitude. Blowing sand mixed with heavy oil smoke to further obscure...Analysts go off into the murky world of materiel marketing . Allow the OR scientists return to the pure mode of enhancing combat operations. If necessary...Roots of Stategy , Book 2 (Harrisburg, Pa.: Stackpole Books, 1987), p. 66. 36 Larry H. Addington, The Patterns of War Since the 18th Century

  2. Roundup

    ERIC Educational Resources Information Center

    Intercom, 1971

    1971-01-01

    This consists of several topical selections: World Affairs. General; Arms Control and Disarmament; International Organizations; Regional Problems and how they relate to World Stability; Air, Trade and Development; and Ethics and War. Each section covers organizational activity and resources. (JB)

  3. Notes on the Gulf War, Racism, and African-American Social Thought: Ramifications for Teaching.

    ERIC Educational Resources Information Center

    Childs, John Brown

    1991-01-01

    Development and enhancement of multicultural and antiracist educational objectives in classes and educational materials that analyze the connection between racism and militarism are crucial for the development of opposition to U.S. interventionism and war making. African-American community resistance to expressed government explanations of Gulf…

  4. Assuming Identities, Enhancing Understanding: Applying Active Learning Principles to Research Projects

    ERIC Educational Resources Information Center

    Williams, Victoria C.

    2006-01-01

    This paper describes a pedagogical technique employed for an interdisciplinary course on Cold War America. Students had to "become" a fictional person and discuss how political and social changes during the Cold War era would have impacted that person. By doing a semester-long project that required primary source research, this…

  5. Vaccine innovation: lessons from World War II.

    PubMed

    Hoyt, Kendall

    2006-01-01

    World War II marked a watershed in the history of vaccine development as the military, in collaboration with academia and industry, achieved unprecedented levels of innovation in response to war-enhanced disease threats such as influenza and pneumococcal pneumonia. In the 1940s alone, wartime programs contributed to the development of new or significantly improved vaccines for 10 of the 28 vaccine-preventable diseases identified in the 20th century. This article examines the historical significance of military organizations and national security concerns for vaccine development in the United States.

  6. 76 FR 45395 - National Korean War Veterans Armistice Day, 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... Agreement at Panmunjom secured the border near the 38th parallel. Together, American service members and... cause of freedom and stability in East Asia and around the world. Today, we honor the tens of thousands...

  7. Aggressive strategic planning for oral health in Kuwait: a decade of post-war successes.

    PubMed

    Morris, R E; Gillespie, G M; Al Za'abi, F; Al Rashed, B; Al Mahmeed, B E

    2008-01-01

    Strategic planning and implementation of oral health care and disease prevention programmes after the 1990/91 Gulf war are discussed. The key concept was to develop access to care and disease prevention for all Kuwaiti children in government kindergarten/primary schools and to eliminate emphasis on extractions and restorations. Resources were restored to pre-war levels and then increased. Prevention programmes for 150 000 children were established. Prevention funds increased from 7% to 20% of the oral health budget. Prevention-based dentists increased from 9.7% to 28.0% of staff. Rising caries trends were stabilized or reduced by up to 36.8%. Percentage of caries-free primary dentition in children increased up to 37.6%, permanent dentition up to 27.0%. A dentistry school was established.

  8. Kosovo’s Support of NATO Stability and Humanitarian Operations

    DTIC Science & Technology

    2013-12-13

    America. In this aspect, non-recognition of Kosovo’s independence from Spain, Greece, Slovakia and Romania (all NATO member countries) is affecting...including: General Staff Publication, and publication of The War College, and Army Command and General Staff College. However, some sources (mostly...countries faced during the first phase of deployment, during deployment and after deployment in stability operations. 3. Kosovo’s national interest to be

  9. AMERICA’S BASE NETWORK: CREDIBLE DETERRENCE

    DTIC Science & Technology

    2017-04-06

    reduction occurring after World War I.13 Both eras saw decades of instability and warfare replace the economic stability provided by the US and its global...is still in effect today and is based on shared interests in security and stability . The alliance was formally established via an Economic and...Abstract This essay looks at historical US basing strategy in order to understand the geopolitical and economic complexity facing diplomacy of future

  10. War Comes to Bala Morghab: A Tragedy of Policy and Action in Three Acts

    DTIC Science & Technology

    2011-12-01

    real shower in December—a full 5 months after operations had commenced. The North Atlantic Treaty Organization (NATO) side of the FOB improved...Security Assistance Force (ISAF), Stability Operations Integration Cell ( SOIC ), “Murghab District, Badghis District Narrative Assessment, 5 May 2010...available at <http://publicintelligence. net/ufouo-stability-operations-information-center- soic -murghab-district-assessment/>. 3 Ibid. 4 Most facts

  11. Climate control: United States weather modification in the cold war and beyond.

    PubMed

    Harper, Kristine C

    2008-03-01

    Rainmaking, hail busting, fog lifting, snowpack enhancing, lightning suppressing, hurricane snuffing...weather control. At the lunatic fringe of scientific discussion in the early twentieth century--and the subject of newspaper articles with tones ranging from skeptical titters to awestruck wonder--weather modification research became more serious after World War II. In the United States, the 'seeds' of silver iodide and dry ice purported to enhance rainfall and bust hailstorms soon became seeds of controversy from which sprouted attempts by federal, state and local government to control the controllers and exploit 'designer weather' for their own purposes.

  12. Ensuring Strategic Stability In The Second Nuclear Age

    DTIC Science & Technology

    2016-02-16

    War College Carlisle Barracks, PA: Strategic Studies Institute, 2013), 5. 7. John C. Wohlstetter, Sleepwalking with the Bomb, (Seattle, WA...2015_national_security_strategy.pdf. Wohlstetter, John C. Sleepwalking with the Bomb. Seattle, WA: Discovery Institute Press, 2012.

  13. Israeli Emergency Social and Mental Health Services in the Gulf War: Observations and Experiences of a Mental Health Professional.

    ERIC Educational Resources Information Center

    Granot, Hayim

    1995-01-01

    During the Gulf War, Israeli mental health professionals played an invaluable role, but their efforts raise questions about what constitutes an appropriate, supportive response for a population suddenly faced with a hazardous event, whether hostile or not. Discusses the strategies used, with lessons that might enhance the disaster services of any…

  14. Gulf Cooperation Council: search for security in the Persian Gulf

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kechichian, J.A.

    1985-01-01

    This study purports to analyze the conservative Arab monarchies' search for regional security in the Persian Gulf. It speculates on the GCC's future prospects as a vehicle of cooperation in the field of security. Threats to the member states of the GCC stem from the policies pursued by revolutionary Iran, Israel, the Soviet Union and its proxies, and a regime in Iraq. The proposition is developed that these sources of threat present an overwhelming challenge to the security and stability of GCC states. Second, it examines the capabilities of the GCC member states for coping with threats. Conceived broadly, bothmore » military and non-military capabilities are examined. Security relations of the GCC states with external powers as a means of enhancing their abilities to cope more effectively with both internal and external threats are examined. Particular attention is devoted to the domestic consequences of these special relations. Third, it discusses the GCC's reactions to perceived regional threats. These include the Iran-Iraq War, the Arab-Israeli conflict, the Soviet threat, and potential political sources of dissidence in member states. It is argued that although GCC states have adopted a number of joint policies, they did not respond to or initiate action on either the Iranian Revolution, the Palestine conflict, the Soviet occupation of Afghanistan, the Gulf war or the recent Israeli invasion of Lebanon.« less

  15. The survival of 19th-century scientific optimism: the public discourse on science in Belgium in the aftermath of the Great War (ca. 1919-1930).

    PubMed

    Onghena, Sofie

    2011-01-01

    In historiography there is a tendency to see the Great War as marking the end of scientific optimism and the period that followed the war as a time of discord. Connecting to current (inter)national historiographical debate on the question of whether the First World War meant a disruption from the pre-war period or not, this article strives to prove that faith in scientific progress still prevailed in the 1920s. This is shown through the use of Belgium as a case study, which suggests that the generally adopted cultural pessimism in the post-war years did not apply to the public rhetoric of science in this country. Diverse actors -- scientists, industrialists, politicians, the public opinion, and the military staff -- declared a confidence in science, enhanced by wartime results. Furthermore, belief in science in Belgium was not affected by public outcry over the use of mustard gas, unlike in the former belligerent countries where the gas became an unpleasant reminder of how science was used during the war. Even German science with its industrial applications remained the norm after 1918. In fact, the faith in science exhibited during the pre-war years continued to exist, at least until the 1920s, despite anti-German sentiments being voiced by many sections of Belgian society in the immediate aftermath of the war.

  16. 3 CFR 8695 - Proclamation 8695 of July 26, 2011. National Korean War Veterans Armistice Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Armistice Agreement at Panmunjom secured the border near the 38th parallel. Together, American service... cause of freedom and stability in East Asia and around the world. Today, we honor the tens of thousands...

  17. Navigating the profits and pitfalls of governmental partnerships: the ICRC and intergovernmental relief, 1918-23.

    PubMed

    Lowe, Kimberly A

    2015-10-01

    The International Committee of the Red Cross (ICRC) is today a staunch proponent of the need for humanitarian organisations to remain independent of state interests, yet it deliberately solicited intergovernmental intervention in international relief after the First World War of 1914-18. This paper examines why an organisation committed to upholding the independence and impartiality of humanitarian action might still choose to partner with governmental bodies. It also highlights the historical beginnings of a linkage between international aid and geopolitics. To secure governmental funding for refugee relief during the 1920s, the ICRC argued that the humanitarian crises of the post-war years were a threat to the political and social stability of Europe. While this has become axiomatic, the interwar history of the ICRC demonstrates that the perceived connection between relief and geopolitical stability is historically constructed, and that it must continue to be asserted persuasively to be effective. © 2015 The Author(s). Disasters © Overseas Development Institute, 2015.

  18. The relationship between climate change and wars waged between nomadic and farming groups from the Western Han Dynasty to the Tang Dynasty period

    NASA Astrophysics Data System (ADS)

    Su, Y.; Liu, L.; Fang, X. Q.; Ma, Y. N.

    2016-01-01

    In ancient China, shifts in regional productivity of agriculture and animal husbandry, caused by climate change, either led to wars or peaceful relations between nomadic and farming groups. During the period spanning the Western Han Dynasty to the Tang Dynasty, 367 wars were waged between these groups. While 69 % of the wars were initiated by nomads, 62.4 % were won by the farming groups. On a centennial timescale, the battlegrounds were mostly in northern areas (at an average latitude of 38.92° N) during warm periods, moving southward (at an average latitude of 34.66° N) during cold periods. On a decadal timescale, warm climates corresponded to a high incidence of wars (a correlation coefficient of 0.293). While farming groups were inclined to initiate wars during dry and cold periods, their chances of achieving victory were reduced at such times. The main reasons for this are, first, that a warm climate provided a solid material foundation for nomadic and farming groups, contributing especially to enhanced productivity among the former. However, the overriding desire of nomadic groups to expand essential subsistence means led to wars. Second, during cold periods, farming groups moved to and settled in the south, while nomadic groups occupied the Central Plain. Thus, the locations of the battlefields also changed. While other factors also influenced these wars, climate change served as a backdrop, playing an indirect role in wars between these groups.

  19. Monosodium Luminol for Improving Brain Function in Gulf War Illness

    DTIC Science & Technology

    2016-10-01

    Specific Aim 2 studies are focused on examining whether long - term administration of an apt dose of MSL-GVT would alleviate mood and memory dysfunction...and inflammation. 15. SUBJECT TERMS DEET, Gulf war illness, hippocampal neurogenesis, Memory dysfunction, Mood dysfunction, neuroinflammation...doses of MSL-GVT, in comparison to age-matched naive control rats. Thus, short - term (3 weeks of) MSL-GVT treatment is not efficacious for enhancing

  20. Self-report and longitudinal predictors of violence in Iraq and Afghanistan war era veterans.

    PubMed

    Elbogen, Eric B; Johnson, Sally C; Newton, Virginia M; Fuller, Sara; Wagner, H Ryan; Beckham, Jean C

    2013-10-01

    This study, using a longitudinal design, attempted to identify whether self-reported problems with violence were empirically associated with future violent behavior among Iraq and Afghanistan war veterans and whether and how collateral informant interviews enhanced the risk assessment process. Data were gathered from N = 300 participants (n = 150 dyads of Iraq and Afghanistan war veterans and family/friends). The veterans completed baseline and follow-up interviews 3 years later on average, and family/friends provided collateral data on dependent measures at follow-up. Analyses showed that aggression toward others at follow-up was associated with younger age, posttraumatic stress disorder, combat exposure, and a history of having witnessed parental violence growing up. Self-reported problems controlling violence at baseline had robust statistical power in predicting aggression toward others at follow-up. Collateral report enhanced detection of dependent variables: 20% of cases positive for violence toward others would have been missed relying only on self-report. The results identify a subset of Iraq and Afghanistan war veterans at higher risk for problematic postdeployment adjustment and indicate that the veterans' self-report of violence was useful in predicting future aggression. Underreporting of violence was not evidenced by most veterans but could be improved upon by obtaining collateral information.

  1. Nursing Care of Women Veterans of the Iraq and Afghanistan Wars.

    PubMed

    Conard, Patricia L; Armstrong, Myrna L

    2018-04-01

    The Iraq and Afghanistan wars are unlike earlier wars, and the women veterans who have served in them are unlike veterans of earlier wars. Now these veterans are presenting with distinctive general, genitourinary, reproductive, and behavioral health issues. When seeking health care after deployment, they may be accessing multiple health care providers across numerous sites, including the Veterans Health Administration and civilian facilities. Enhanced levels of understanding, respect, and concern for the many combat-related health challenges experienced by these veterans will help civilian nurses and other clinicians provide optimum care. Provision of health care to women veterans should be multidisciplinary and effectively coordinated among various health care providers and facilities to ensure that their post-deployment health and wellness needs are met. © 2018 AWHONN, the Association of Women’s Health, Obstetric and Neonatal Nurses.

  2. (Mutual Security Mutual Affluence) Negative Factors = Sustained Stability: A Framework for Establishing Stability Between Like States

    DTIC Science & Technology

    2017-03-31

    160-163. 2 The Concept of Mutually Assured Destruction (MAD) dates back to the post-WWFI em and the Cold War where the United States and Soviet Unions...United States. Following its defeat in W\\VH, Japan was in shambles. The bombing campaigns left nine million Japanese homeless and three million more...the United States, the Charlie Hebdo attacks in Paris in 2015, and the bombings in Istanbul in 2016. Michael Bamier, “From Mutual Assistance to

  3. The Impact of Globalization on African Conflicts

    DTIC Science & Technology

    2003-01-01

    There is no region of this world that not experienced wars, but while many parts of the world have moved towards greater political and economic ... stability and co-operation, sub-Saharan Africa remains a cauldron of instability and economic deprivation. Globalization, which in simple terms means a

  4. The End of the End of Ideology

    ERIC Educational Resources Information Center

    Jost, John T.

    2006-01-01

    The "end of ideology" was declared by social scientists in the aftermath of World War II. They argued that: (1) ordinary citizens' political attitudes lack the kind of stability, consistency, and constraint that ideology requires; (2) ideological constructs such as liberalism and conservatism lack motivational potency and behavioral…

  5. The pebbles that started the tea and ohelo berry projects in Hawaii

    USDA-ARS?s Scientific Manuscript database

    Hawaii farmers face many challenges in production including high cost of operation, limitation of affordable land, infra-structure, energy and human resources. After World War II, success in agricultural research into new crops contributed to the economic development and stability in Hawaii. Some...

  6. U.S. Foreign Policy Priorities.

    ERIC Educational Resources Information Center

    Pell, Claiborne

    1983-01-01

    The three highest priorities for American foreign policy are avoiding nuclear war by working with the Soviet leadership to alter our present collision course, demonstrating our commitment to human rights throughout the world, and ensuring American economic prosperity by strengthening exports and ensuring the stability of the international monetary…

  7. A Non-Conventional Interdiction Strategy for the Global War on Terror

    DTIC Science & Technology

    2007-06-01

    thesis is to explore an alternative strategic focus for the Department of Defense to implement in the conduct of the Global War on Terrorism. Our...thesis is as follows: A non-conventional approach to strategic policy, led by an enhanced Foreign Internal Defense concept, and judicious execution of...been and continues to be limited by its conventional tactical successes, when what is required is strategic application of FID, UW, and limited

  8. South Sudan and the Emerging Security Implications for East Africa

    ERIC Educational Resources Information Center

    Akuey, Aldo Ajou Deng

    2018-01-01

    South Sudan achieved political independence in 2011, before plunging into a series of civil wars that have culminated with the signing of the Inter-Governmental Authority for Development, IGAD, driven peace agreement. The Sudan People's Liberation Movement, SPLM, Government has not created conducive environment for political stability in South…

  9. Legitimacy and Penetration in Stability Operations; Setting the Conditions for Perpetual Failure

    DTIC Science & Technology

    2011-12-02

    District or Provincial level. Taking the lessons from Vietnam and 124 Michael Crawshaw , Running a Country: The British Colonial Experience and its Relevance...Metrics of the Afghan War. CSIS presentation, Washington DC: Center for Strategic and International Studies, 2010. Crawshaw , Michael. Running a Country

  10. Shaping Columbia’s Stability through Strategic Communication: Evaluating U.S. Effectiveness

    DTIC Science & Technology

    2009-05-21

    113-114. The authors have adapted the 10 Step framework for military applicability from Philip Kotler , Ned Roberto, and Nancy Lee, Social Marketing...Qaida. Santa Monica: RAND Corporation, 2008. Keegan, John. The Iraq War. New York: Alfred A. Knopf, 2004. Kotler , Philip , Ned Roberto, and Nancy

  11. Strategic Analysis of the Asia-Pacific Region: Is a Forward-Based Aircraft Carrier Required in the Post-Cold War Era?

    DTIC Science & Technology

    1991-06-07

    in maintaining regional stability moreso than forward-deploying from CONUS. See regional perspectives above and caveats. - Although the fcrwarcd-based...retainz defense responsibilities moreso than a forward-deployed strategy could, barring increaed deployment lengths. (Cost Comparison) A cost

  12. The potential of treating Gulf War Illness with curcumin.

    PubMed

    Leibowitz, Jeffrey A; Ormerod, Brandi K

    2018-05-01

    A large proportion of Gulf War Veterans suffer from Gulf War Illness (GWI) - a devastating chronic disorder characterized by heterogeneous fatigue, pain and neuropsychological symptoms. In their recent Brain, Behavior and Immunity publication entitled "Curcumin Treatment Leads to Better Cognitive and Mood Function in a Model of Gulf War Illness with Enhanced Neurogenesis, and Alleviation of Inflammation and Mitochondrial Dysfunction in the Hippocampus", Kodali and colleagues (2018) report that the polyphenol curcumin improves cognition and mood in a rat model of GWI, potentially by increasing the expression of antioxidant genes and by reversing the effects of chronic combined acetylcholinesterase inhibitor exposure on neuroinflammation, mitochondrial respiration and hippocampal neurogenesis. This preclinical work is encouraging for our veterans who suffer chronically from GWI as well as for developing strategies to protect our troops during future deployments in similar environments. Copyright © 2018 Elsevier Inc. All rights reserved.

  13. [The organization of maternity and child care in the Buryat-Mongolskaya ASSR during the Great Patriotic War].

    PubMed

    Batoev, S D

    2010-01-01

    In Ulan-Ude, in 1942, the mortality of children at the age from 0 to 15 years consisted 64% of total numbers of died persons. The main causes of children mortality during all the war were tuberculosis, pneumonia, toxic dyspepsia and diarrhea. In October 1942, the government adopted a special decree obligated Narcomzdrav of the USSR to re-establish the system of maternity and child care existed before the war. The focus was made on the district principle of functioning of women and children consultations and polyclinics and to take measures to enhance the children diet and food vitaminization. In Buryat-Mongolskaya ASSR, during the war period, no epidemics of infectious diseases were allowed. In this difficult period of life the first multifield children hospital and municipal infection hospital with children beds were established and functioned with success.

  14. War, terrorism, and children.

    PubMed

    DeRanieri, Joseph T; Clements, Paul T; Clark, Kathleen; Kuhn, Douglas Wolcik; Manno, Martin S

    2004-04-01

    Many caregivers are encountering the issue of communicating with children and adolescents about current world events, specifically war and terrorism. As health care providers, it is important to raise awareness of how children may understand, interpret, and respond to related fears and concerns. Although honesty and reassurance are clearly the best approach, it is important to provide information that is developmentally appropriate. Providing education and guidance can reduce stress and enhance understanding of the chaotic events confronting our nation. It also provides a platform for communication and exploration should additional terrorist attacks or acts of war occur. It is important to examine how to approach children and adolescents to communicate with them about these sensitive issues.

  15. Postwar City: Importance of Recycling Construction and Demolition Waste

    NASA Astrophysics Data System (ADS)

    Al-Qaraghuli, Hanan; Alsayed, Yaman; Almoghazy, Ali

    2017-10-01

    Wars and armed conflicts have heavy tolls on the built environment when they take place in cities. It is not only restricted to the actually fighting which destroys or damages buildings and infrastructure, but the damage and destruction inflicts its impacts way beyond the cessation of military actions. They can even have another impact through physical segregation of city quarters through walls and checkpoints that complicates, or even terminates, mobility of citizens, goods, and services in the post-war scenario. The accumulation of debris in the streets often impedes the processes of rescue, distribution of aid and services, and other forms of city life as well. Also, the amount of effort and energy needed to remove those residual materials to their final dumping sites divert a lot of urgently needed resources. In this paper, the components of construction and demolition waste found in post-war cities are to be discussed, relating each one to its origins and potential reuses. Then the issues related to the management of construction waste and demolition debris resulting from military actions are to be discussed. First, an outlook is to be given on the historical example of Berlin and how the city was severely damaged during World War II, and how the reconstruction of the city was aided in part by the reuse of demolition debris. Then two more recent examples will be given, the cities of Baghdad in Iraq, and Homs in Syria. In Baghdad, though major military actions have ceased but not all rubble is cleared out, some security structures in the form of concrete walls separate the cities into quarters and impede city life and lie around as poorly allocated resource needed for reconstruction. While in the case of Homs, and the wider Syrian context, major military operations are still raging, making more pressure on the resources needed for reconstruction. This recycling of demolition debris can bring economic and social stability through the conservation of resources, creation of jobs, and - eventually - the stabilization of the society in the midst of an atrocious war. Suggestions for relevant solutions will be given in both cities.

  16. Experiences of a support group for interns in the setting of war and political turmoil.

    PubMed

    El Jamil, Fatima; Hamadeh, Ghassan N; Osman, Hibah

    2007-10-01

    Intern support groups have been instituted in many residency programs to improve resident well-being. In this article, we discuss the themes that emerged in intern support group meetings in a family medicine program operating in a setting of war and political instability. We held support groups, led by a family physician and a psychologist, that met monthly. Participants were residents in the family medicine program at the American University of Beirut. These residents began their training days after the commencement of the 34-day war between Israel and Hizbollah in 2006. Themes and issues discussed by the residents were noted and are reported in this article. We found that despite the stressors of the political situation, our interns focused on the usual stress of internship, such as the difficulties of functioning as interns in other departments and dealing with the time demands of internship as their main sources of stress at the beginning of internship. The stresses associated with the war did not emerge in the group until later in the year. These included tension with patients and political confrontations with staff, as well as personal struggles with the lack of political stability and depressed mood. This paper serves to share our experience and highlight some areas of concern that residents experience when training in a country or region that is at war.

  17. Dual-hormone stress reactivity predicts downstream war-zone stress-evoked PTSD.

    PubMed

    Josephs, Robert A; Cobb, Adam R; Lancaster, Cynthia L; Lee, Han-Joo; Telch, Michael J

    2017-04-01

    The crucial role of the hypothalamic-pituitary-adrenal axis (HPA) in stress-related homeostasis suggests dysregulated HPA involvement in the pathogenesis of post-traumatic stress disorder (PTSD), yet most studies examining linkages between HPA axis measures and PTSD have yielded null findings. One untested explanation for this inconsistency is a failure to account for simultaneous adrenal and gonadal influence. Here we tested the singular and interactive effects of cortisol (C R ) and testosterone (T R ) reactivity as moderators of war-zone stress evoked PTSD emergence in the war-zone. U.S. soldiers (N=120) scheduled for deployment to Iraq completed pre-deployment measures of C R and T R stress reactivity to a CO 2 inhalation challenge. Once deployed, monthly assessments of exposure to traumatic war-zone stressors and PTSD symptoms were collected via a web-based assessment system. Cortisol hypo-reactivity potentiated the pathogenic impact of war-zone stressors only in soldiers for whom the CO 2 challenge did not elevate testosterone, suggesting that the dual hormone stress reactivity profile of blunted cortisol and testosterone may confer increased risk for PTSD emergence by potentiating the pathogenic effects of war-zone stressors. Findings underscore the utility of assessing both HPA and HPG stress reactivity when assessing PTSD vulnerability and may help inform efforts for enhanced soldier screening and inoculation to war-zone stressors. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Brief Psychoeducational Group Treatment with Re-Traumatized Refugees and Asylum Seekers

    ERIC Educational Resources Information Center

    Akinsulure-Smith, Adeyinka M.

    2009-01-01

    This article describes the implementation of a psychoeducational group treatment with students with a history of refugee trauma, war, and human rights abuses who were further traumatized by the 9/11 attacks in New York City. The rationale for group intervention and specific techniques utilized to promote emotional and behavioral stabilization and…

  19. A Global Outreach Plan for Colleges

    ERIC Educational Resources Information Center

    Skorton, David J.

    2007-01-01

    Speaking at a Harvard University commencement 60 years ago, Secretary of State George C. Marshall proposed a massive program of aid and redevelopment--since known as the Marshall Plan--to bring a war-ravaged Europe back to economic health, political stability, and peace. Today colleges and universities need a new such plan, with university…

  20. Linguistic Markets in Rwanda: Language Use in Advertisements and on Signs

    ERIC Educational Resources Information Center

    Rosendal, Tove

    2009-01-01

    Rwanda has experienced major changes during the last decade due to the genocide in 1994. After the civil war, in addition to establishing political and economical stability, peace and reconciliation, the government was faced with the return of refugees from neighbouring, mostly English-speaking, countries. The new socio-demographic conditions…

  1. On the history of the development of solid-propellant rockets in the Soviet Union

    NASA Technical Reports Server (NTRS)

    Pobedonostsev, Y. A.

    1977-01-01

    Pre-World War II Soviet solid-propellant rocket technology is reviewed. Research and development regarding solid composite preparations of pyroxyline TNT powder is described, as well as early work on rocket loading calculations, problems of flight stability, and aircraft rocket launching and ground rocket launching capabilities.

  2. Meeting EFA: Afghanistan Community Schools

    ERIC Educational Resources Information Center

    Balwanz; David

    2007-01-01

    From 1979 to 2002, Afghanistan was in a near constant state of war and exhibited some of the lowest levels of development in the world. While local conflicts and Taliban remnants continue to challenge Afghanistan's reconstruction and stabilization, significant progress has been made since the 2001 U.S. led invasion and subsequent fall of the…

  3. Croatian Membership in NATO: One of the Crucial Prerequisites for Stabilization of Southeastern Europe

    DTIC Science & Technology

    2002-03-01

    CROATIA – A HISTORICAL OVERVIEW..........................................................15 A. CROATIA UNTIL 1918 ...16 B. CROATIA UNDER SERBIAN DOMINATION 1918 -1991 ......................21 1. World War II...Hungarian Empire, and finally a part of Yugoslavia from 1918 -1991. Despite their lack of independence for a period of almost nine centuries

  4. The Need for Transition

    DTIC Science & Technology

    2013-05-01

    scrambling to recover ever since.39 Major Isaiah Wilson, who served as an official historian of the campaign and later as a war planner in Iraq, wrote...2 Headquarters Department of the Army, Stability Operations. FM 3-07 (Washington, DC: U.S. Army, October 2008), 1-1. 3 Thomas E. Ricks...38 Crane, 12. 39 Thomas

  5. The World's Women: Fighting a Battle, Losing the War.

    ERIC Educational Resources Information Center

    Abernethy, Virginia

    1993-01-01

    Promulgates the position that the overpopulation issue is being coopted for women's health and social status. Questions whether or not raising women's status in itself will have any significant impact on lowering fertility rates. Suggests that the attempt to stabilize populations through empowerment of women is a dangerous mistake in societies…

  6. The Specter of Sunni Military Mobilization in Lebanon

    DTIC Science & Technology

    2013-11-01

    stabilization  Future national security environment and forces  European security issues, especially the Mediterranean littoral  West Africa...5  More space for militant narratives .......................................................... 8  The Syrian war comes...their political dominance  Sunni officials and elites attack the legitimacy of state institu- tions, particularly the Lebanese Army  The Future

  7. Entering the New Millennium: Dilemmas in Arms Control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    BROWN,JAMES

    The end of the Cold War finds the international community no longer divided into two opposing blocks. The concerns that the community now faces are becoming more fluid, less focused, and, in many ways, much less predictable. Issues of religion, ethnicity, and nationalism; the possible proliferation of Weapons of Mass Destruction; and the diffusion of technology and information processing throughout the world community have greatly changed the international security landscape in the last decade. Although our challenges appear formidable, the United Nations, State Parties, nongovernmental organizations, and the arms control community are moving to address and lessen these concerns throughmore » both formal and informal efforts. Many of the multilateral agreements (e.g., NPT, BWC, CWC, CTBT, MTCR), as well as the bilateral efforts that are taking place between Washington and Moscow employ confidence-building and transparency measures. These measures along with on-site inspection and other verification procedures lessen suspicion and distrust and reduce uncertainty, thus enhancing stability, confidence, and cooperation.« less

  8. Offshore wind farms as productive sites or ecological traps for gadoid fishes?--impact on growth, condition index and diet composition.

    PubMed

    Reubens, Jan T; Vandendriessche, Sofie; Zenner, Annemie N; Degraer, Steven; Vincx, Magda

    2013-09-01

    With the construction of wind farms all across the North Sea, numerous artificial reefs are created. These windmill artificial reefs (WARs) harbour high abundances of fish species which can be attracted from elsewhere or can be the result of extra production induced by these wind farms. To resolve the attraction-production debate in suddenly altered ecosystems (cf. wind farms), the possible consequences of attraction should be assessed; thereby bearing in mind that ecological traps may arise. In this paper we investigated whether the wind farms in the Belgian part of the North Sea act as ecological traps for pouting and Atlantic cod. Length-at-age, condition and diet composition of fish present at the windmill artificial reefs was compared to local and regional sandy areas. Fish data from the period 2009-2012 were evaluated. Mainly I- and II-group Atlantic cod were present around the WARs; while the 0- and I-group dominated for pouting. For Atlantic cod, no differences in length were observed between sites, indicating that fitness was comparable at the WARs and in sandy areas. No significant differences in condition index were observed for pouting. At the WARs, they were slightly larger and stomach fullness was enhanced compared to the surrounding sandy areas. Also diet differed considerably among the sites. The outcome of the proxies indicate that fitness of pouting was slightly enhanced compared to the surrounding sandy areas. No evidence was obtained supporting the hypothesis that the WARs act as an ecological trap for Atlantic cod and pouting. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Auditory processing assessment suggests that Wistar audiogenic rat neural networks are prone to entrainment.

    PubMed

    Pinto, Hyorrana Priscila Pereira; Carvalho, Vinícius Rezende; Medeiros, Daniel de Castro; Almeida, Ana Flávia Santos; Mendes, Eduardo Mazoni Andrade Marçal; Moraes, Márcio Flávio Dutra

    2017-04-07

    Epilepsy is a neurological disease related to the occurrence of pathological oscillatory activity, but the basic physiological mechanisms of seizure remain to be understood. Our working hypothesis is that specific sensory processing circuits may present abnormally enhanced predisposition for coordinated firing in the dysfunctional brain. Such facilitated entrainment could share a similar mechanistic process as those expediting the propagation of epileptiform activity throughout the brain. To test this hypothesis, we employed the Wistar audiogenic rat (WAR) reflex animal model, which is characterized by having seizures triggered reliably by sound. Sound stimulation was modulated in amplitude to produce an auditory steady-state-evoked response (ASSR; -53.71Hz) that covers bottom-up and top-down processing in a time scale compatible with the dynamics of the epileptic condition. Data from inferior colliculus (IC) c-Fos immunohistochemistry and electrographic recordings were gathered for both the control Wistar group and WARs. Under 85-dB SLP auditory stimulation, compared to controls, the WARs presented higher number of Fos-positive cells (at IC and auditory temporal lobe) and a significant increase in ASSR-normalized energy. Similarly, the 110-dB SLP sound stimulation also statistically increased ASSR-normalized energy during ictal and post-ictal periods. However, at the transition from the physiological to pathological state (pre-ictal period), the WAR ASSR analysis demonstrated a decline in normalized energy and a significant increase in circular variance values compared to that of controls. These results indicate an enhanced coordinated firing state for WARs, except immediately before seizure onset (suggesting pre-ictal neuronal desynchronization with external sensory drive). These results suggest a competing myriad of interferences among different networks that after seizure onset converge to a massive oscillatory circuit. Copyright © 2017 IBRO. Published by Elsevier Ltd. All rights reserved.

  10. How did Japanese rural dwellers become rapidly healthier in the two decades following World War II?: Examining the diverse policy interventions that improved the population's health.

    PubMed

    Yuasa, Motoyuki

    2017-01-01

    Objective During the two decades following Japan's World War II surrender in 1945, tremendous improvement in the population's health was observed, particularly in infant mortality and life expectancy. How did Japanese rural dwellers achieve such remarkable health improvement during this relatively short time span while its economy remained heavily damaged following the war? While the efforts from government-driven public health strategies and programs are well known, relatively little is known about the contributions of policies in non-health sectors. Therefore, the main aim is to verify, using literature based sources, whether non-health sectors contributed to the betterment of the population's health in addition to the public health sector policies.Hypotheses Synergistic efforts of diverse interventions from different policies and programs likely catalyzed the drastic health improvement observed in the Japanese population in the two decades after World War II. The Ministry of Health and Welfare, for example, implemented programs to provide health care services. These are thought to have contributed directly to reducing maternal and child mortality, as well as tuberculosis-related mortality. Additionally, the Ministry of Agriculture and Forestry carried out a nationwide livelihood improvement program to enhance individual and family lifestyles, improve indoor and outdoor environments, and strengthen social solidarity. The ministry also attempted to generate income stability for farmers through an agricultural improvement program to ensure allocation of household income to family health. The Ministry of Education also had an initiative to disseminate the concepts of democracy and rational thought to the Japanese population through a social education program. Through these efforts, superstition and pre-modern customs were reduced, and subsequently health awareness increased, leading to an improvement in the population's health.Conclusion The public health policies implemented in Japan as well as the integration of various policies and programs addressing livelihoods, economics, and education greatly improved the population's health in a relatively short time. These non-health initiatives intersected with a wide range of health determinants. Verifying these hypotheses in detail would help develop effective measures for international aid to poverty-stricken regions. It also encourages alternative ways through which Japan could overcome its present-day challenges such as a rapidly aging population with limited access to national schemes for social security.

  11. Designing, Testing and Using Command, Control, Communications, Computer, and Intelligence (C4I) Systems: What Causes the Disconnects and What Can Be Done About Them?

    DTIC Science & Technology

    1994-06-01

    numbers on a Cathode Ray Tube (CRT) visual display or monochrome monitor. Gradually, pictures and color were added to enhance this interaction...apparent that there are very strong interactions among the political, economic, and military aspects of national power. Although the NCA will...classified according to the levels of war. Which level of war best describes your experience with C4I systems? Strategic - NCA (Nuclear) Operational

  12. Violence and reproductive health preceding flight from war: accounts from Somali born women in Sweden.

    PubMed

    Byrskog, Ulrika; Olsson, Pia; Essén, Birgitta; Allvin, Marie Klingberg

    2014-08-30

    Political violence and war are push factors for migration and social determinants of health among migrants. Somali migration to Sweden has increased threefold since 2004, and now comprises refugees with more than 20 years of war experiences. Health is influenced by earlier life experiences with adverse sexual and reproductive health, violence, and mental distress being linked. Adverse pregnancy outcomes are reported among Somali born refugees in high-income countries. The aim of this study was to explore experiences and perceptions on war, violence, and reproductive health before migration among Somali born women in Sweden. Qualitative semi-structured individual interviews were conducted with 17 Somali born refugee women of fertile age living in Sweden. Thematic analysis was applied. Before migration, widespread war-related violence in the community had created fear, separation, and interruption in daily life in Somalia, and power based restrictions limited access to reproductive health services. The lack of justice and support for women exposed to non-partner sexual violence or intimate partner violence reinforced the risk of shame, stigmatization, and silence. Social networks, stoicism, and faith constituted survival strategies in the context of war. Several factors reinforced non-disclosure of violence exposure among the Somali born women before migration. Therefore, violence-related illness might be overlooked in the health care system. Survival strategies shaped by war contain resources for resilience and enhancement of well-being and sexual and reproductive health and rights in receiving countries after migration.

  13. Conventional Prompt Global Strike: Valuable Military Option or Threat to Global Stability?

    DTIC Science & Technology

    2005-09-01

    The Strategic Rocket Forces, 1991-2002,” in Russian Military Reform : 1992- 2002, ed. Anne C. Aldis and Roger McDermott (Portland, OR: Frank Cass...Redefining the Threat and the War on Terrorism,” in Russian Military Reform 1992-2002, ed. Anne C. Aldis and Roger N. Mc Dermott (Portland, OR: Frank...

  14. Siegfried S. Hecker, Plutonium, and Nonproliferation

    Science.gov Websites

    controversy involving the stability of certain structures (or phases) in plutonium alloys near equilibrium Cold War is Over. What Now?, DOE Technical Report, April, 1995 6th US-Russian Pu Science Workshop * Aging of Plutonium and Its Alloys * A Tale of Two Diagrams * Plutonium and Its Alloys-From Atoms to

  15. Center for Strategic Leadership Issue Paper, August 2007, Volume 8-07. Military Education Workshop Addresses Threats to Stability and Security.

    DTIC Science & Technology

    2007-08-01

    upcoming National Intelligence Estimate (NIE), the National Inteligence Council (NIC) has reached out to a broad group of U.S. government organizations and...USAF (Retired) Major Shannon Beebe U.S. ARMY WAR COLLEGE Center for Strategic Leadership 650 Wright Avenue Carlisle, PA 17103-5049 OFFICIAL BUSINESS

  16. Cyberspace Human Capital: Building a Cadre Today to Win Tomorrows War

    DTIC Science & Technology

    2016-04-28

    sustainable and flexible framework that manages and develops a cyberspace cadre, today and into the future. This professional paper examines USAF and DoD...future conflicts, USAF leadership must develop a sustainable and flexible framework that manages and develops cyberspace cadre...international security and stability. CYBERSPACE FORCE MANAGEMENT ACCESSIONS RETENTION INSTITUTIONAL STRUCTURE FORCE DEVELOPMENT EDUCATION TRAINING

  17. From world war to class war: the rebound of the rich.

    PubMed

    Evans, Robert G

    2006-07-01

    Incomes in Canada, as in many other countries, are becoming increasingly unequal. In North America this process has several notable features. First, after 40 years of stability, income has since 1980 been increasingly concentrated in the hands of the top 0.01% of earners. Second, this concentration correlates with an explosion in the relative earnings of corporate CEOs, a sort of "corporate kleptocracy." Third, the top earners have appropriated most of the productivity gains over this period. The resources and political influence of the super-rich underlie the growing prominence of the "elite" agenda: lower taxes, smaller government and privatization or shrinkage of social programs. The marketing of this agenda may explain much of the nonsense that contaminates health policy debates.

  18. Emergence of social cohesion in a model society of greedy, mobile individuals

    PubMed Central

    Roca, Carlos P.; Helbing, Dirk

    2011-01-01

    Human wellbeing in modern societies relies on social cohesion, which can be characterized by high levels of cooperation and a large number of social ties. Both features, however, are frequently challenged by individual self-interest. In fact, the stability of social and economic systems can suddenly break down as the recent financial crisis and outbreaks of civil wars illustrate. To understand the conditions for the emergence and robustness of social cohesion, we simulate the creation of public goods among mobile agents, assuming that behavioral changes are determined by individual satisfaction. Specifically, we study a generalized win-stay-lose-shift learning model, which is only based on previous experience and rules out greenbeard effects that would allow individuals to guess future gains. The most noteworthy aspect of this model is that it promotes cooperation in social dilemma situations despite very low information requirements and without assuming imitation, a shadow of the future, reputation effects, signaling, or punishment. We find that moderate greediness favors social cohesionby a coevolution between cooperation and spatial organization, additionally showing that those cooperation-enforcing levels of greediness can be evolutionarily selected. However, a maladaptive trend of increasing greediness, although enhancing individuals’ returns in the beginning, eventually causes cooperation and social relationships to fall apart. Our model is, therefore, expected to shed light on the long-standing problem of the emergence and stability of cooperative behavior. PMID:21709245

  19. Emergence of social cohesion in a model society of greedy, mobile individuals.

    PubMed

    Roca, Carlos P; Helbing, Dirk

    2011-07-12

    Human wellbeing in modern societies relies on social cohesion, which can be characterized by high levels of cooperation and a large number of social ties. Both features, however, are frequently challenged by individual self-interest. In fact, the stability of social and economic systems can suddenly break down as the recent financial crisis and outbreaks of civil wars illustrate. To understand the conditions for the emergence and robustness of social cohesion, we simulate the creation of public goods among mobile agents, assuming that behavioral changes are determined by individual satisfaction. Specifically, we study a generalized win-stay-lose-shift learning model, which is only based on previous experience and rules out greenbeard effects that would allow individuals to guess future gains. The most noteworthy aspect of this model is that it promotes cooperation in social dilemma situations despite very low information requirements and without assuming imitation, a shadow of the future, reputation effects, signaling, or punishment. We find that moderate greediness favors social cohesion by a coevolution between cooperation and spatial organization, additionally showing that those cooperation-enforcing levels of greediness can be evolutionarily selected. However, a maladaptive trend of increasing greediness, although enhancing individuals' returns in the beginning, eventually causes cooperation and social relationships to fall apart. Our model is, therefore, expected to shed light on the long-standing problem of the emergence and stability of cooperative behavior.

  20. Defense Logistics: Enhanced Policy and Procedures Needed to Improve Management of Sensitive Conventional Ammunition

    DTIC Science & Technology

    2016-02-01

    Information System-Retail OIS-MC Ordnance Information System-Marine Corps SAAS -MOD Standard Army Ammunition System-Modernization SRC Security Risk...automated information systems. For the Army we used LMP, SAAS , and WARS-NT; for the Navy and Marine Corps we used OIS-W, OIS-R, and OIS-MC; and for the Air...Army we used LMP, SAAS , and WARS-NT; for the Navy and Marine Corps we used OIS-W, OIS-R, and OIS-MC; and for the Air Force we used CAS. Military

  1. Why Did U.S. Healthcare Professionals Become Involved in Torture During the War on Terror?

    PubMed

    Balfe, Myles

    2016-09-01

    This article examines why U.S. healthcare professionals became involved in "enhanced interrogation," or torture, during the War on Terror. A number of factors are identified including a desire on the part of these professionals to defend their country and fellow citizens from future attack; having their activities approved and authorized by legitimate command structures; financial incentives; and wanting to prevent serious harm from occurring to prisoners/detainees. The factors outlined here suggest that psychosocial factors can influence health professionals' ethical decision-making.

  2. The Analytic Hierarchy Process: Enhancing Operational Level Decision Making

    DTIC Science & Technology

    1993-03-10

    USN 13 TPEOFWO713b. ?WE COVERED 4L. DAT! OF, RIM" ( fta *. NWkO Isi P*MA 001MFAMo to__ / izI 16. SUP"LE MNIARY NOTATION A p ibaikitted the Pl Faat o b...TakQrce The FaajdsWar,.9-82 (New York: Viking Penguin , Inc, Rev. ed., 1988). 26 1. MISSION. To seize the Falkland Islands and eject Argentinian...Falklands War4 1982 (New York: Viking Penguin , Inc, Rev. ed., 1988). Max Hastings and Simon Jenkins, The Battle for the Falklands (New York: W. W. Norton

  3. Thrust and parry of the SIOP (single integrated operational plan) and sdi (strategic defense initiative). Research report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zank, G.D.

    1989-05-01

    The relationship between strategic offensive capabilities (reflected in the SIOP) and emerging strategic defensive capabilities (reflected by SDI) is not being adequately addressed. A summary of the existing nuclear war planning process is provided, and an analagous defensive process is postulated. Parallels and differences between the two processes are discussed. Potential areas for information exchange and cooperation are identified to enhance deterrence and improve war fighting potential. Operational, technical and political issues requiring resolution are raised and recommendations to resolve these issues are made.

  4. Cyber Deterrence and Stability

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goychayev, Rustam; Carr, Geoffrey A.; Weise, Rachel A.

    Throughout the 20th and early 21st centuries, deterrence and arms control have been cornerstones of strategic stability between the superpowers. However, the weaponization of the cyber realm by State actors and the multipolar nature of cyber conflict now undermines that stability. Strategic stability is the state in which nations believe that if they act aggressively to undermine U.S. national interests and the post-World War II liberal democratic order, the consequences will outweigh the benefits. The sense of lawlessness and lack of consequences in the cyber realm embolden States to be more aggressive in taking actions that undermine stability. Accordingly, thismore » paper examines 1) the role of deterrence and arms control in securing cyber stability, and 2) the limitations and challenges associated with these traditional national security paradigms as applied to this emerging threat domain. This paper demonstrates that many 20th-century deterrence and arms control concepts are not particularly applicable in the cyber realm. However, they are not entirely irrelevant. The United States can distill lessons learned from this rich deterrence and arms control experience to develop and deploy a strategy to advance cyber stability.« less

  5. Neal Lane: Science in a Flat World

    ScienceCinema

    Lane, Neal

    2017-12-22

    Lane discusses the changes that have taken place in the world since World War II that have made it "flatter," referring to Thomas L. Friedman's book, The World is Flat. Friedman's main premise is that inexpensive telecommunications is bringing about unhampered international competition, the demise of economic stability, and a trend toward outsourcing services, such as computer programming, engineering and science research.

  6. 3 CFR 8543 - Proclamation 8543 of July 26, 2010. National Korean War Veterans Armistice Day, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... of the United States of America A Proclamation Today we celebrate the signing of the Military... respect, and this partnership is vital to peace and stability in Asia and the world. Since our Nation’s... rallied to the young republic’s defense. Tens of thousands of our Nation’s servicemembers lost their lives...

  7. Iraq: Post-Saddam Governance and Security

    DTIC Science & Technology

    2009-04-02

    after British forces defeated the Ottomans in World War I and took control of the territory in 1918 . Britain had tried to take Iraq from the Ottomans...International Religions Freedom Report, September 2008; DOD Measuring Stability Report, March 2009; various press and other documents...September 19, 2008, report on International Religious Freedom attributed restrictions on the free exercise of religion (by religious minorities) to

  8. Human Cognitive Enhancement Ethical Implications for Airman-Machine Teaming

    DTIC Science & Technology

    2017-04-06

    34 Psychological Constructs versus Neural Mechanisms: Different Perspectives for Advanced Research of Cognitive Processes and Development of Neuroadaptive...AIR WAR COLLEGE AIR UNIVERSITY HUMAN COGNITIVE ENHANCEMENT ETHICAL IMPLICATIONS FOR AIRMAN-MACHINE TEAMING by William M. Curlin...increasingly challenging adversarial threats. It is hypothesized that by the year 2030, human system operators will be “ cognitively challenged” to keep pace

  9. Enhancing the Future Strategic Corporal

    DTIC Science & Technology

    2006-01-01

    with greater firepower than ever before, the Strategic Corporal will be charged with greater responsibility than ever before, while the potential for...translation of “Strategic Corporal ”, and the article responsible for popularizing the term, see General Charles C. Krulak, “The Strategic Corporal ...Quantico, Virginia 22134-5068 FUTURE WAR PAPER ENHANCING THE FUTURE STRATEGIC CORPORAL SUBMITTED IN PARTIAL FULFILLMENT OF THE

  10. NASA Astrophysics Data System (ADS)

    Schweber, Silvan S.

    2014-06-01

    Some facets of the life of Hans Bethe after World War II are presented to illustrate how Paul Forman's works, and in particular his various theses—on mathematics and physics in Wilhelmine and Weimar Germany, on physics in the immediate post-World War II period, and on postmodernity—have influenced my biography of Bethe. Some aspects of the history of post-World War II quantum field theory, of solid state/condensed matter physics, and of the development of neoliberalism—the commitment to the belief that the market knows best, to free trade, to enhanced privatization, and to a drastic reduction of the government's role in regulating the economy—are reviewed in order to make some observations regarding certain "top-down" views in solid state physics in postmodernity, the economic and cultural condition of many Western societies since the 1980s, the decade in which many historians assume modernity to have ended.

  11. The early days of optical coatings

    NASA Astrophysics Data System (ADS)

    Macleod, Angus

    1999-12-01

    The history of optical coatings is a long one with many observations and publications but little industrial activity until a period of explosive growth began in the 1940s. The trigger was World War II and the need on all sides for improved optical instruments ranging from binoculars to periscopes and bombsights, but it is certain that the growth would have occurred, perhaps a year or two later, even without the war. After the war the growth continued, partly because of military needs, but much more because of other factors such as the continuing growth in general optics, the enormous expansion of the chemical industry and its need for infrared and visible analytical tools, the need for narrowband contrast enhancing filters in astronomy, and then, very significantly, the laser. Nowadays, optical coatings are indispensible features of virtually all optical systems.

  12. Using art as a self-regulating tool in a war situation: a model for social workers.

    PubMed

    Huss, Ephrat; Sarid, Orly; Cwikel, Julie

    2010-08-01

    War poses a challenge for social workers, adding exposure to direct risk of personal harm to the general stress of social work practice. Artworks are frequently used in health care settings with people in high distress. This study had three goals: (1) to characterize the stressors of social workers living in a war zone, (2) to teach social workers in crisis situations to identify stress and resilience factors in their artworks, and (3) to develop a general self-care model for arts intervention for professionals in these situations. Common stressors experienced by participants were anxiety and fear as a result of bombs, sirens, worry over loved ones, and overexposure to media. These were layered onto professional stressors, including constant work communication on cell phones during war and dilemmas related to work-family conflicts. Allowing social workers to name and identity the sources of their stress and then change their artwork to enhance resilience helped them to gain a sense of control over diffuse sources of anxiety. The authors propose this method as an effective intervention model with social workers in high-stress situations.

  13. [Epidemiological situation of infectious diseases in Lvov and Cracow during and after World War I (until the year 1922)].

    PubMed

    Berner, Włodzimierz

    2009-01-01

    In Lvov and Cracow at the times of World War I, the infectious diseases such as tuberculosis followed by typhus fever, typhoid fever, dysentery, as well as scarlet fever, diphtheria, measles, whooping cough, smallpox, cholera and venereal diseases (particularly syphilis) posed one of the most significant and dangerous problems for inhabitants. Their increased prevalence was the result of deteriorating sanitary and living conditions of the city population. The spread of epidemic infectious diseases was enhanced by marching troops, migration of civilians and war prisoners, return of large groups of displaced people and demobilized soldiers after regaining independence in November 1918. Additionally, unfavorable epidemiological situation in Lvov deteriorated at the time of the war with Ukrainians (November 1918-April 1919) and Bolsheviks (July-August 1920). The control of infectious diseases was in the hands of regional local physicians who referred patients to hospitals, isolated homes, bath and disinfection institutions, and conducted vaccinations against smallpox. A decrease in infectious diseases prevalence and deaths to the prewar levels occurred in 1922.

  14. Periodic climate cooling enhanced natural disasters and wars in China during AD 10–1900

    PubMed Central

    Zhang, Zhibin; Tian, Huidong; Cazelles, Bernard; Kausrud, Kyrre L.; Bräuning, Achim; Guo, Fang; Stenseth, Nils Chr

    2010-01-01

    Recent studies have linked climatic and social instabilities in ancient China; the underlying causal mechanisms have, however, often not been quantitatively assessed. Here, using historical records and palaeoclimatic reconstructions during AD 10–1900, we demonstrate that war frequency, price of rice, locust plague, drought frequency, flood frequency and temperature in China show two predominant periodic bands around 160 and 320 years where they interact significantly with each other. Temperature cooling shows direct positive association with the frequency of external aggression war to the Chinese dynasties mostly from the northern pastoral nomadic societies, and indirect positive association with the frequency of internal war within the Chinese dynasties through drought and locust plagues. The collapses of the agricultural dynasties of the Han, Tang, Song and Ming are more closely associated with low temperature. Our study suggests that food production during the last two millennia has been more unstable during cooler periods, resulting in more social conflicts owing to rebellions within the dynasties or/and southward aggressions from northern pastoral nomadic societies in ancient China. PMID:20630883

  15. Periodic climate cooling enhanced natural disasters and wars in China during AD 10-1900.

    PubMed

    Zhang, Zhibin; Tian, Huidong; Cazelles, Bernard; Kausrud, Kyrre L; Bräuning, Achim; Guo, Fang; Stenseth, Nils Chr

    2010-12-22

    Recent studies have linked climatic and social instabilities in ancient China; the underlying causal mechanisms have, however, often not been quantitatively assessed. Here, using historical records and palaeoclimatic reconstructions during AD 10-1900, we demonstrate that war frequency, price of rice, locust plague, drought frequency, flood frequency and temperature in China show two predominant periodic bands around 160 and 320 years where they interact significantly with each other. Temperature cooling shows direct positive association with the frequency of external aggression war to the Chinese dynasties mostly from the northern pastoral nomadic societies, and indirect positive association with the frequency of internal war within the Chinese dynasties through drought and locust plagues. The collapses of the agricultural dynasties of the Han, Tang, Song and Ming are more closely associated with low temperature. Our study suggests that food production during the last two millennia has been more unstable during cooler periods, resulting in more social conflicts owing to rebellions within the dynasties or/and southward aggressions from northern pastoral nomadic societies in ancient China.

  16. Wistar audiogenic rats display abnormal behavioral traits associated with artificial selection for seizure susceptibility.

    PubMed

    Castro, Gabriel Perfeito; Medeiros, Daniel de Castro; Guarnieri, Leonardo de Oliveira; Mourão, Flávio Afonso Gonçalves; Pinto, Hyorrana Priscila Pereira; Pereira, Grace Schenatto; Moraes, Márcio Flávio Dutra

    2017-06-01

    Accumulating evidence from different animal models has contributed to the understanding of the bidirectional comorbidity associations between the epileptic condition and behavioral abnormalities. A strain of animals inbred to enhance seizure predisposition to high-intensity sound stimulation, the Wistar audiogenic rat (WAR), underwent several behavioral tests: forced swim test (FST), open-field test (OFT), sucrose preference test (SPT), elevated plus maze (EPM), social preference (SP), marble burying test (MBT), inhibitory avoidance (IAT), and two-way active avoidance (TWAA). The choice of tests aimed to investigate the correlation between underlying circuits believed to be participating in both WAR's innate susceptibility to sound-triggered seizures and the neurobiological substrates associated with test performance. Comparing WAR with its Wistar counterpart (i.e., resistant to audiogenic seizures) showed that WARs present behavioral despair traits (e.g., increased FST immobility) but no evidence of anhedonic behavior (e.g., increased sucrose consumption in SPT) or social impairment (e.g., no difference regarding juvenile exploration in SP). In addition, tests suggested that WARs are unable to properly evaluate degrees of aversiveness (e.g., performance on OFT, EPM, MBT, IAT, and TWAA). The particularities of the WAR model opens new venues to further untangle the neurobiology underlying the co-morbidity of behavioral disorders and epilepsy. This article is part of a Special Issue entitled "Genetic and Reflex Epilepsies, Audiogenic Seizures and Strains: From Experimental Models to the Clinic". Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Financial Well-Being and Post-Deployment Adjustment among Iraq and Afghanistan War Veterans

    PubMed Central

    Elbogen, Eric B.; Johnson, CAPT Sally C.; Wagner, H. Ryan; Newton, Virginia M.; Beckham, Jean C.

    2012-01-01

    Research has yet to examine the relationship between financial well-being and community reintegration of veterans. To address this, we analyzed data from n=1,388 Iraq and Afghanistan War Era Veterans who completed a national survey on post-deployment adjustment. The results indicated that probable major depressive disorder, posttraumatic stress disorder, and traumatic brain injury were associated with financial difficulties. However, regardless of diagnosis, veterans who reported having money to cover basic needs were significantly less likely to have post-deployment adjustment problems such as criminal arrest, homelessness, substance abuse, suicidal behavior, and aggression. Statistical analyses also indicated that poor money management (e.g. incurring significant debt or writing bad checks) was related to maladjustment, even among veterans at higher income levels. Given these findings, efforts aimed at enhancing financial literacy and promoting meaningful employment may have promise to enhance outcomes and improve quality of life among returning veterans. PMID:22730842

  18. Explosive Remnants of War in Stability Operations

    DTIC Science & Technology

    2012-09-01

    strategic partner capacity building, global ERW and Counter-IED (C-IED) efforts, while adhering to global Mine /UXO awareness efforts. 15. NUMBER OF...PAGES 139 14. SUBJECT TERMS Explosive Remnants of War—Collection Point (ERW - CP), Landmine, Anti- Personnel Mine , Mine Action, Cluster Munitions...strategic partner capacity building, global ERW and Counter- IED (C-IED) efforts, while adhering to global Mine /UXO awareness efforts. vi THIS PAGE

  19. Global Arms Trade: Commerce in Advanced Military Technology and Weapons,

    DTIC Science & Technology

    1991-06-01

    executive branch interactions over secu- rity assistance and conventional arms control is presented. Those already familiar with this area may...Aerospatiale MBB OTO Melara Matra Thomson-CSF Thyssen Contraves Oerlikon Plessey British Manufacturing & Research British Aerospace...buying 50 Shaldags to use in its war on drugs . Toward the close of the decade Israel Shipyards’ financial situation stabilized thanks to extensive cost

  20. Stability in Pakistan: Realizing the Vision of Enlightened Moderation

    DTIC Science & Technology

    2006-06-01

    official policy or position of the Department of Defense or the U.S. Government. 12a. DISTRIBUTION / AVAILABILITY STATEMENT Approved for public...the region and the United States’ War on Terror as his constraints, President General Pervez Musharraf finds himself in a position where success now...General Pervez Musharraf finds himself in a position where success now is crucial, not optional. vi THIS

  1. Enabling Persistent Peace After Negotiated Settlements

    DTIC Science & Technology

    2016-12-01

    event either party fails to comply with the agreements, especially on the issue of power sharing, recurrence of conflict is high . Another cause...persistent peace after a negotiated settlement when the government holds a majority of the power . Additionally, an examination of Mozambique’s civil war...provisions can be used to stabilize expectations and reduce uncertainty. When adversaries agree to share power , this action can prolong the peace by

  2. Annual Report to Congress

    DTIC Science & Technology

    2008-05-01

    other product areas. Where unmet requirements are identified and where S&T is required to meet cost objectives, the CBRN defense homeland security... industrial base, which has scaled down since the end of the Cold War, has stabilized. Ongoing military operations and homeland defense initiatives...as well as shelf-life expirations for stockpiles built in the 1980s, have contributed to demand for industrial base services and products

  3. War and Escalation in South Asia

    DTIC Science & Technology

    2006-01-01

    their foreign area officer expertise in the region, especially through language training (p. 85). Summary xv • Review special operations forces...stability, based on an effective central gov- ernment and denial of safe haven for terrorists. In Nepal and Sri Lanka, we will support processes to...U.S.-Pakistan Defense Consultative Group processes — has historically proven the highest-leverage U.S. policy instrument. The Near East South Asia

  4. Iraq: Post-Saddam Governance and Security

    DTIC Science & Technology

    2008-11-19

    control of the territory in 1918 . Britain had tried to take Iraq from the Ottomans earlier in World War I but were defeated at Al Kut in 1916...Sources: CIA The World Factbook; State Department International Religions Freedom Report, September 2007; DOD Measuring Stability Report, September...2008 report on International Religious Freedom attributed restrictions on the free exercise of religion (by religious minorities) to “terrorists

  5. Influence: Maximizing Effects to Create Long-Term Stability

    DTIC Science & Technology

    2010-05-03

    Kilcullen, in a 2007 NOETIC brief, delineates popular perception into the emotive (“hearts”) component and the cognitive (“minds”) component. x...viii Zachary Abuza, “Balik Islam: The Return of Abu Sayyaf” (information paper, Carlisle, PA: U. S. Army War College, Strategic Studies Institute), 2...Strategic Studies Institute, 2005. Abuza, Zachary. Militant Islam in Southeast Asia: Crucible of Terror. Boulder, CO: Lynne Rienner Publishers, Inc

  6. Borrowed buildings: Canada's temporary hospitals during World War I.

    PubMed

    Adams, A

    1999-01-01

    This article explores the alterations and additions made to houses, colleges, and larger public buildings in their temporary use as convalescent homes for wounded Canadian soldiers during World War I. These ''borrowed buildings'' anticipated and emphasized three important characteristics of subsequent hospital architecture by suggesting that domestic environments enhanced healing, that hospitals should be accessible, and that patients should be segregated according to social status and disease. The broader implications of the study are that temporarily appropriated spaces contribute to the definition of many institutions and often act as arenas of resistance to established practices.

  7. The Libyan civil conflict: selected case series of orthopaedic trauma managed in Malta in 2014.

    PubMed

    Ng, Colin; Mifsud, Max; Borg, Joseph N; Mizzi, Colin

    2015-11-20

    The purpose of this series of cases was to analyse our management of orthopaedic trauma casualties in the Libyan civil war crisis in the European summer of 2014. We looked at both damage control orthopaedics and for case variety of war trauma at a civilian hospital. Due to our geographical proximity to Libya, Malta was the closest European tertiary referral centre. Having only one Level 1 trauma care hospital in our country, our Trauma and Orthopaedics department played a pivotal role in the management of Libyan battlefield injuries. Our aims were to assess acute outcomes and short term mortality of surgery within the perspective of a damage control orthopaedic strategy whereby aggressive wound management, early fixation using relative stability principles, antibiotic cover with adequate soft tissue cover are paramount. We also aim to describe the variety of war injuries we came across, with a goal for future improvement in regards to service providing. Prospective collection of six interesting cases with severe limb and spinal injuries sustained in Libya during the Libyan civil war between June and November 2014. We applied current trends in the treatment of war injuries, specifically in damage control orthopaedic strategy and converting to definitive treatment where permissible. The majority of our cases were classified as most severe (Type IIIB/C) according to the Gustilo-Anderson classification of open fractures. The injuries treated reflected the type of standard and improved weaponry available in modern warfare affecting both militants and civilians alike with increasing severity and extent of damage. Due to this fact, multidisciplinary team approach to patient centred care was utilised with an ultimate aim of swift recovery and early mobilisation. It also highlighted the difficulties and complex issues required on a hospital management level as a neighbouring country to war zone countries in transforming care of civil trauma to military trauma.

  8. The role of the sand in chemical warfare agent exposure among Persian Gulf War veterans: Al Eskan disease and "dirty dust".

    PubMed

    Korényi-Both, A L; Svéd, L; Korényi-Both, G E; Juncer, D J; Korényi-Both, A L; Székely, A

    2000-05-01

    The purpose of this paper is to inquire into the relationship between Al Eskan disease and the probable exposure to chemical warfare agents by Persian Gulf War veterans. Al Eskan disease, first reported in 1991, compromises the body's immunological defense and is a result of the pathogenic properties of the extremely fine, dusty sand located in the central and eastern region of the Arabian peninsula. The disease manifests with localized expression of multisystem disorder. Signs and symptoms of Al Eskan disease have been termed by the news media "Persian Gulf syndrome." The dust becomes a warfare agent when toxic chemicals are microimpregnated into inert particles. The "dirty dust" concept, that the toxicity of an agent could be enhanced by absorption into inactive particles, dates from World War I. A growing body of evidence shows that coalition forces have encountered Iraqi chemical warfare in the theater of operation/Persian Gulf War to a much greater extent than early U.S. Department of Defense information had indicated. Veterans of that war were exposed to chemical warfare agents in the form of direct (deliberate) attacks by chemical weapons, such as missiles and mines, and indirect (accidental) contamination from demolished munition production plants and storage areas, or otherwise. We conclude that the microimpregnated sand particles in the theater of operation/Persian Gulf War depleted the immune system and simultaneously acted as vehicles for low-intensity exposure to chemical warfare agents and had a modifying-intensifying effect on the toxicity of exposed individuals. We recommend recognition of a new term, "dirty sand," as a subcategory of dirty dust/dusty chemical warfare agents. Our ongoing research efforts to investigate the health impact of chemical warfare agent exposure among Persian Gulf War veterans suggest that Al Eskan disease is a plausible and preeminent explanation for the preponderance of Persian Gulf War illnesses.

  9. Oral history: Validating contributions of elders.

    PubMed

    Taft, Lois B; Stolder, Mary Ellen; Knutson, Alice Briolat; Tamke, Karolyn; Platt, Jennifer; Bowlds, Tara

    2004-01-01

    Recording memories of World War II is an intervention that can humanize geriatric care in addition to the historical significance provided. Participants in this oral history project described memories of World War II and expressed themes of patriotism, loss, tense moments, makeshift living, self-sufficiency, and uncertain journey. Their ethnic roots were primarily Scandinavian, Dutch, German, and English. The nursing home participants were slightly older than the community participants (mean ages: 85.5 and 82.4 years, respectively). More women (58%) than men (42%) participated, and 35% of the participants were veterans (eight men one woman). Nursing home and community residents participated in this project, and reciprocal benefits were experienced by participants and listeners alike. Memories of World War II provide a meaningful topic for oral histories. Listening and valuing oral history supports, involves, and validates elders. Oral history has reciprocal benefits that can create a culture to enhance a therapeutic environment.

  10. Thermal-inertial ratchet effects: negative mobility, resonant activation, noise-enhanced stability, and noise-weakened stability.

    PubMed

    Li, Jing-hui; Łuczka, Jerzy

    2010-10-01

    Transport properties of a Brownian particle in thermal-inertial ratchets subject to an external time-oscillatory drive and a constant bias force are investigated. Since the phenomena of negative mobility, resonant activation and noise-enhance stability were reported before, in the present paper, we report some additional aspects of negative mobility, resonant activation and noise-enhance stability, such as the ingredients for the appearances of these phenomena, multiple resonant activation peaks, current reversals, noise-weakened stability, and so on.

  11. GPR and ERT detection and characterization of a mass burial, Spanish Civil War, Northern Spain.

    PubMed

    Rubio-Melendi, David; Gonzalez-Quirós, Andrés; Roberts, Daniel; García García, María Del Carmen; Caunedo Domínguez, Amaya; Pringle, Jamie K; Fernández-Álvarez, José-Paulino

    2018-06-01

    Around 27,000 people were killed in the province of Asturias during the Spanish Civil War, with several thousands killed after the war ended. There are currently over 2,000 known mass burial locations throughout Spain, but many more are unknown. Geophysics is a useful tool employed to help in the active attempts to document and improve knowledge about victims from this conflict. This paper details a non-invasive study of the Cementerio de El Salvador, in the city of Oviedo, Northern Spain. Part of the cemetery contains a known mass burial with approximately 1,300 individuals from the Spanish Civil War and post-war repression eras. Multi-frequency near-surface geophysical techniques were undertaken, after permission, to enhance knowledge about which, if any, techniques should be used to detect, delineate and analyse such mass graves. Multi-frequency (250MHz and 500MHz) ground-penetrating radar surveys were acquired together with 2D and 3D Electrical Resistivity Tomography datasets. The results have established the limits of the mass grave and improve the knowledge of the internal mass grave structure. The paper also shows the importance of considering the climatic conditions during data acquisition. This has important implications for the successful detection of recent historical mass burials using near-surface geophysics. Copyright © 2018 Elsevier B.V. All rights reserved.

  12. DECISION SUPPORT SYSTEM TO ENHANCE AND ENCOURAGE SUSTAINABLE CHEMICAL PROCESS DESIGN

    EPA Science Inventory

    There is an opportunity to minimize the potential environmental impacts (PEIs) of industrial chemical processes by providing process designers with timely data nad models elucidating environmentally favorable design options. The second generation of the Waste Reduction (WAR) algo...

  13. More a plowshare than a sword: the legacy of US Cold War agricultural diplomacy.

    PubMed

    McGlade, Jacqueline

    2009-01-01

    Recently, agriculture has assumed an elevated role in world diplomacy due to pressing issues like international poverty relief, changing environmental conditions, farm trade imbalances, rising food prices, and the diversion of crops into bio-fuel production. Consequently, agricultural interests and production have become increasingly entwined with the politics of national protectionism and identity, domestic security, and the preservation of trading advantage in developed and developing countries alike. This study examines the current impasse in world agricultural negotiations as an outgrowth of US foreign aid and trade policymaking as it evolved during the Cold War. In particular, it chronicles the historic shift in US foreign policy away from "give-away" food aid and surplus sales and toward the championing of global agricultural redevelopment under such programs as the Marshall Plan and PL 480, the Food for Peace program. As more a plowshare than a sword, the American Cold War push for worldwide agricultural modernization led many countries to experience new levels of food self-efficiency and export capabilities. Along with production parity, however, has come escalating levels of trade competition and national protectionism, which challenges again the achievement of world agricultural stability and prosperity.

  14. Refugee Children in Sweden: Post-Traumatic Stress Disorder in Iranian Preschool Children Exposed to Organized Violence.

    ERIC Educational Resources Information Center

    Almqvist, Kjerstin; Brandell-Forsberg, Margareta

    1997-01-01

    Evaluation of the incidence of post-traumatic stress disorder (PTSD) in 50 preschool children from 47 Iranian families living as refugees in Sweden found a rise of PTSD from 2% to 21% in the 42 children with traumatic exposure through war and political persecution. Stability of prevalence was high in follow-up 2 and 2.5 years later. (Author/DB)

  15. Hard Lessons: The Iraq Reconstruction Experience

    DTIC Science & Technology

    2009-02-01

    late to influence pre- war planning.81 Moreover, the completed reports proved of varying utility . The Transitional Justice Working Group, for example...the import of more than a billion dollars in spare parts and equipment under the Oil-for-Food program, Iraq’s production capacity only marginally ...from the Future of Iraq Project and experts across the government to draft contingency plans to prevent a mone - tary collapse and stabilize Iraqi

  16. Revitalizing Nuclear Operations in the Joint Environment

    DTIC Science & Technology

    2014-02-01

    height of the Cold War, US schol - ars and joint operational planners were working simultaneously on weapons development and operational art to employ...leadership’s large-target- category withholds thought necessary to maintain stability in a strategic crisis. The inclusion of nuclear effects and...escalation. The inclusion of these points in tomorrow’s doctrine as well as an intellec- tual discussion on the topic will inform Joint Staff planners

  17. The DTIC Review, Urban Warfare. Volume 4, Number 4

    DTIC Science & Technology

    1999-08-01

    International Committee of the Red Cross (ICRC), Handbook on the Law of War for Armed Forces, by Frederic de Mulinen (Geneva: International Committee of the Red...or developing logistical stabilizing force within a volatile region - or as Cupporfornatng oravopng logistica demonstration of US political...attack. It can be described as an in combat formations. After seizing the objec- arrow or dagger thrust into the enemy de -in ombt frmaion

  18. Independent Assessment of the Afghan National Security Forces

    DTIC Science & Technology

    2014-01-01

    increase the likelihood of ANSF success through 2018 , thereby improving the longer-term prospects for a negotiated political settlement to end the war. We...Afghanistan through 2018 ; con- ducted a troop-to-task analysis of ANSF force structure required to achieve these operational objectives; identified...the Taliban insurgency will become a greater threat to Afghanistan’s stability in the 2015– 2018 timeframe than it is now. The insurgency has been

  19. The 2015 Transition of Wartime Operational Control: A Threat or Opportunity for the ROK /US Alliance

    DTIC Science & Technology

    2014-06-13

    effects in regional stability. In other words, as Matthew J. Jordan pointed out, multilateral efforts will complement and not supplant established...operations. 46Matthew J. Jordan , “Multilateralism in North East Asia” (Master’s Naval War College...dismantling DPRK’s nuclear program. The impetus for these talks emerged in 2003 when the DPRK revealed its uranium enrichment program. This enrichment

  20. ASEAN and Indochina: A Strategy for Regional Stability in the 1980’s.

    DTIC Science & Technology

    1984-12-01

    regional powers. The resultant regional balance of power is precarious, unstable, and ever threatens to deteriorate into armed conflict. The unequal...an armed force that is capable of large scale defense. Ironically, while ostensibly defensively motivated, these efforts have resulted in a war machine... resulted in the atmosphere of tense uncertainty in Southeast Asia today. In contrast to Vietnamese motivations for their force -- structure, the other

  1. Wage and Salary Stabilization in a National Security Emergency

    DTIC Science & Technology

    1984-10-01

    Arkansas Houston, Texas Eldorado, AR Bryan, TX Fayetteville, AR Lufkin, TX 2-8 Wage and Salary 2 - 9 . Region VI cont. Fort Smith, AR Waco, TX Jonesboro , AR ...applied to: financial and monetary systems: wages, salaries, and benefits; prices; rents; and rationing of essential goods. These measures are ...in terms of a number of conditions. They are : CONDITION I: Peacetime CONDITION II: National emergency (Threat of war) CONDITION ILIA: Mobilization

  2. Stability in the Offense: The Evolution of Civil Affairs During World War II

    DTIC Science & Technology

    2014-05-22

    Department of State ETO European Theater of Operation ETOUSA European Theater United States Army FACT Field Advance Civilian Teams FM Field Manual...monograph. Official histories include Harry L. Cole and Albert K . Weinberg’s Civil Affairs: Soldiers Become Governors, which provides an extensive...US Historical Experience with Civil Affairs: 10Harry L. Coles and Albert K . Weinberg, Civil Affairs: Soldiers Become Governors, CMH Pub 11-5

  3. Not the Drones You’re Looking for: Civil Drones Invading Stability Operations

    DTIC Science & Technology

    2016-06-01

    APPROVAL The undersigned certify that this thesis meets master’s-level standards of research , argumentation, and expression...Naval War College in 2015. His career as a developmental engineer and acquisition officer has included assignments at the Air Force Research ...culmination of not only an extensive research effort, but of an academic and intellectual journey two years in the making and I would be remiss to end

  4. Do Fewer Resources Mean Less Influence? A Comparative Historical Case Study of Military Influence in a Time of Austerity

    DTIC Science & Technology

    2015-01-01

    including suggestions for reducing this burden, to Washington Headquarters Services , Directorate for Information Operations and Reports, 1215 Jefferson...and DEVELOPMENT The United States Army War College educates and develops leaders for service at the strategic level while advancing knowledge in the...expert knowledge, and provides solutions to strategic Army issues affecting the national security community . The Peacekeeping and Stability Operations

  5. Strategic Stability in the Cold War: Lessons for Continuing Challenges

    DTIC Science & Technology

    2011-01-01

    Moltz, Daniel Moran, Thomas Parker, Joseph Pilat , Pavel Podvig, Brad Roberts, Michael Rühle, Diego Ruiz Palmer, Thomas Scheber, Mark Schneider, Paul...differ. As Joseph Pilat has observed, terrorist organizations “have historically mimicked states in key areas and are thus subject to constraints and...Press, 2008, p. 60. 62 Joseph F. Pilat , “Dissuasion of Terrorists and Other Non-State Actors”, Strategic Insights, Vol.III, Issue 10, October

  6. Iraq: Post-Saddam Governance and Security

    DTIC Science & Technology

    2008-10-02

    the Ottoman empire after British forces defeated the Ottomans in World War I and took control of the territory in 1918 . Britain had tried to take Iraq... Religions Freedom Report, September 2007; DOD Measuring Stability Report, September 2008. CRS-3 1 Bush, George H.W., and Brent Scowcroft. A World...politically. Similarly, the September 19, 2008 report on International Religious Freedom attributed restrictions on the free exercise of religion (by

  7. Iraq: Post-Saddam Governance and Security

    DTIC Science & Technology

    2008-08-12

    took control of the territory in 1918 . Britain had tried to take Iraq from the Ottomans earlier in World War I but were defeated at Al Kut in 1916... Religions Freedom Report, September 2007; DOD Measuring Stability Report, June 2008. CRS-3 1 Bush, George H.W., and Brent Scowcroft. A World Transformed...Armenia, Slovakia, Denmark, El Salvador, Ukraine, Romania , Lithuania, Latvia, Mongolia, and Kazakhstan. Polish forces number 900, down from a high

  8. Great Power Concert: Competition, Cooperation, and Stability in East Africa

    DTIC Science & Technology

    2013-06-01

    PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) School Of Advanced Air And Space Studies,,Air University,,Maxwell Air Force Base,,AL 8. PERFORMING... ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT...alliances. Establishing international institutions like the United Nations and the North Atlantic Treaty Organization during the post-World War II era, the

  9. Thermonuclear peace, the tightrope of deterrence

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Uscher, A.R.

    This policy analysis focuses on the actions and approaches that will best reduce the chances of nuclear war in a MAD world, where mutual terror and mutual dependence will define our bipolar environment for the foreseeable future. The general approach to this broad and complex issue can be summarized as follows: since plans for conducting and preventing nuclear war are likely to be self-fulfilling prophecies, the US should strive for rational declaratory and deployment policies that reduce the chance of nuclear conflict while maintaining our national-security interests. Stability, probably the single most-important and unifying theme in nuclear deterrence, is visualizedmore » as a set of incentive structures that create no perceived advantages in escalating at any point along a hypothetical-force continuum. The key element in establishing and maintaining superpower stability is the inability to achieve adequate damage limitation through a preemptive first strike. The power and number of nuclear weapons compared to the fragility and limited number of priority targets seriously challenge the utility of most defensive measures. Successfully walking the tightrope of deterrence will require careful balancing of legitimate and competing values. This is a difficult task, but with a clear and realistic vision of the future, it is a feasible one.« less

  10. Mental health in Japanese members of the United Nations peacekeeping contingent in the Golan Heights: effects of deployment and the Middle East situation.

    PubMed

    Sawamura, Takehito; Shimizu, Kunio; Masaki, Yoshinori; Kobayashi, Nobuhisa; Sugawara, Mariko; Tsunoda, Tomoya; Kikuchi, Akihito; Yamamoto, Taisuke; Toda, Hiroyuki; Nomura, Soichiro; Takahashi, Yoshitomo; Oryu, Takashi; Ogasawara, Tsuneyuki; Ogata, Katsuhiko

    2008-01-01

    This study evaluates the mental health of Japan Self-Defense Force (JSDF) members of the peacekeeping contingent in the Golan Heights before and since the Second Gulf War between 1998 and 2003. Before the war, the General Health Questionnaire 30 (GHQ30) scores during and after duty tended to be lower than those before duty; all scores were lower than those of adult Japanese men in general. After the war, GHQ30 scores did not significantly change between before, during, and after duty. Manifest Anxiety Scale (MAS) scores were not significantly different between groups. Stressors identified included problems with foreign language and familial matters at home. Post war stressors included work content and relationships with collaborating foreign army units. These findings suggest that the mental health of contingent members remained stable, with some variation in mental health conditions influenced by the situation in the Middle East. This study suggests that the stable mental condition of JSDF personnel during their deployment in the absence of combat, and that this could be enhanced by education about mental health issues and by providing counseling support to their families. (c) 2008 APA, all rights reserved

  11. Preparing the Field for Feasibility Testing of a Parenting Intervention for War-Affected Mothers in Northern Uganda.

    PubMed

    Wieling, Elizabeth; Mehus, Christopher; Yumbul, Cigdem; Möllerherm, Julia; Ertl, Verena; Laura, Achan; Forgatch, Marion; Neuner, Frank; Catani, Claudia

    2017-06-01

    In this article, we discuss the successful implementation of an adapted evidence-based parenting intervention for families affected by two decades of war in Northern Uganda. The adaptation and adoption of such interventions to support mental health and family functioning is widely endorsed by prevention scientists and considered a priority in global mental health. The preparation and early adoption phases of engaging with a highly vulnerable community affected by war trauma are documented in this paper along with a discussion of the steps taken to adapt a parenting intervention for cultural and contextual fit. This study is a component of an overall program of research aimed at reducing the long-term negative effects of war on parenting practices and childhood outcomes, which have considerable implications for preventing mental, neurological, and substance-use disorders. The processes described here cover a 4-year period culminating in the implementation of the nine-session Enhancing Family Connection intervention piloted with a group of 14 mothers. The lessons in cultural adaptation have been valuable and the feasibility results promising for further testing the intervention. © 2015 Family Process Institute.

  12. Military medical advances resulting from the conflict in Korea, Part I: Systems advances that enhanced patient survival.

    PubMed

    Baker, Michael S

    2012-04-01

    The Korean War started several years after the World War II had ended and no recognition of the threat or preparation was made for this possibility. The military and its medical service had been downsized after World War II and had to quickly ramp up to meet the surprise attack. The war provided the laboratory for trials and experimentation with the new technological developments of the era. The Korean conflict led to numerous advances in medical systems and patient care. The Mobile Army Surgical Hospital came of age, and was instrumental in saving many lives. Helicopters saw their first regular use as flying ambulances to take the injured to definitive care in a timely fashion. The national blood banking program was rapidly geared up and new techniques such as plastic bags for collection and delivery resulted. Body armor was developed that would allow mobility while offering protection and was widely used for the first time. Each of these systems improvements saved the lives of soldiers in combat and were soon to be used in the civilian sector to save and improve lives around the world.

  13. Plastic Surgery Challenges in War Wounded I: Flap-Based Extremity Reconstruction

    PubMed Central

    Sabino, Jennifer M.; Slater, Julia; Valerio, Ian L.

    2016-01-01

    Scope and Significance: Reconstruction of traumatic injuries requiring tissue transfer begins with aggressive resuscitation and stabilization. Systematic advances in acute casualty care at the point of injury have improved survival and allowed for increasingly complex treatment before definitive reconstruction at tertiary medical facilities outside the combat zone. As a result, the complexity of the limb salvage algorithm has increased over 14 years of combat activities in Iraq and Afghanistan. Problem: Severe poly-extremity trauma in combat casualties has led to a large number of extremity salvage cases. Advanced reconstructive techniques coupled with regenerative medicine applications have played a critical role in the restoration, recovery, and rehabilitation of functional limb salvage. Translational Relevance: The past 14 years of war trauma have increased our understanding of tissue transfer for extremity reconstruction in the treatment of combat casualties. Injury patterns, flap choice, and reconstruction timing are critical variables to consider for optimal outcomes. Clinical Relevance: Subacute reconstruction with specifically chosen flap tissue and donor site location based on individual injuries result in successful tissue transfer, even in critically injured patients. These considerations can be combined with regenerative therapies to optimize massive wound coverage and limb salvage form and function in previously active patients. Summary: Traditional soft tissue reconstruction is integral in the treatment of war extremity trauma. Pedicle and free flaps are a critically important part of the reconstructive ladder for salvaging extreme extremity injuries that are seen as a result of the current practice of war. PMID:27679751

  14. The enhanced stability and biodegradation of dispersed crude oil droplets by Xanthan Gum as an additive of chemical dispersant.

    PubMed

    Wang, Aiqin; Li, Yiming; Yang, Xiaolong; Bao, Mutai; Cheng, Hua

    2017-05-15

    It is necessary for chemical dispersant to disperse oil effectively and maintain the stability of oil droplets. In this work, Xanthan Gum (XG) was used as an environmentally friendly additive in oil dispersant formulation to enhance the stability and biodegradation of dispersed crude oil droplets. When XG was used together with chemical dispersant 9500A, the dispersion effectiveness of crude oil in artificial sea water (ASW) and the oil droplet stability were both greatly enhanced. In the presence of XG, lower concentration of 9500A was needed to achieve the effective dispersion and stabilization. In addition to the enhancement of dispersion and stabilization, it was found that the biodegradation rate of crude oil by bacteria was dramatically enhanced when a mixture of 9500A and XG was used as a dispersant. Because of the low environmental impact of XG, this would be a potential way to formulate the dispersant with lower toxicity. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Disaster-Proofing Senior Leadership: Preventing Technological Failure in Future Nano-War

    DTIC Science & Technology

    2009-02-01

    phenomenon beyond Globalization 3.0, where the empowered individual becomes the empowered machine-enhanced human or cyborg in 50 to 100 years. This merging...gain control of their bodies, could turn into superhuman cyborg - like upgrades. Further, the ability to understand and replicate brain functions in...The implications of nano-enhanced humans and cyborgs on the battlefield are legion. With ubiquitous sensing via the quantum dot-sized sensor nets

  16. Charting Russia's Future in the Post-Soviet Era. Eighth Edition. Teacher Resource Book [and Student Text]. Public Policy Debate in the Classroom. Choices for the 21st Century.

    ERIC Educational Resources Information Center

    Fox, Sarah Cleveland

    Russia struggle with questions of identity and economic stability sine ending its Cold War relationship with the United States. In this unit students are asked to see the world through Russian eyes and to contemplate Russian choices in the areas of economic development, political organization, and foreign policy. The unit focuses on three distinct…

  17. Measuring Oman’s Food Security Outlook for Crisis Aversion

    DTIC Science & Technology

    2015-05-18

    unemployment benefits as well as more powers to the Majlis al-Shura.7 However, Oman could lose political stability in another food price spike, so it remains...population growth, arid climate, and government mismanagement has led to failing agricultural sectors and economic vulnerability.12 Today, most Arab...and two civil wars in Yemen and Syria continue today.19 While international organizations and non- governmental organizations like the World Bank and

  18. Measuring the Immeasurable: Applying Hierarchical Holographic Modeling to Developing Measures of Effectiveness for Stability, Security, Transition, and Reconstruction Operations

    DTIC Science & Technology

    2006-05-16

    and Internally Displaced Persons (IDPs) Judicial Personnel and Infrastructure Trafficking in Persons Property Food Security Legal System Reform...Shelter and Non- Food Relief Human Rights Humanitarian Demining Corrections Public Health War Crime Courts and Tribunals Education Truth...Risk Analysis, 22(2) (2002): 385. 26 Ibid. 27 Ibid. 28 Dombroski, 20. 29 Keith R. Hayes, “Final Report: Inductive Hazard Analysis for GMOs

  19. Longitudinal Effects of Job Change Upon Interest Utilization and Satisfaction Attitudes.

    DTIC Science & Technology

    1980-10-01

    USAF Commander SUBJECT TO EXPORT CONTROL LAWS This document contains information for manufacturing or using munitions of war. Export of the information...contained herein, or release to foreign nationals within the United States, without first obtaining an export license, is a violation of the...information was then interpreted as an index of the stability of a job type over time. The second kind of information indicating which job types the

  20. Analysis of United Nations Millennium Summit Speeches

    DTIC Science & Technology

    2001-04-01

    Development 36 46 Taiwan 14 16 Terrorism 32 60 Transnational Crime 31 40 Urban-Rural 2 12 War 65 108 Water 15 20 Weapons 36 62 Women/ Gender ...Concept Number of Countries Freq. of Mention Governance 47 59 Aid/Assistance for Dev. 44 58 Sovereignty 36 53 Women/ Gender Equality 38 50...take into consideration how different cultures consider the special status of elders and gender responsibilities. Social stability has to be considered

  1. Operating in the Gray Zone: An Alternative Paradigm for U.S. Military Strategy

    DTIC Science & Technology

    2016-04-01

    labeling, or re-labeling, may have been to draw the attention of busy policymakers to rapidly emerging security issues , it has evolved into something... issues affecting the national security community. The Peacekeeping and Stability Operations Institute provides subject matter expertise, technical...SSI) is part of the U.S. Army War College and is the strategic-level study agent for issues related to national security and military strategy with

  2. Sustainment of Expeditionary Forces in the Pacific Theater during the Second World War: The Development of the Advanced Base and Mobile Base Programs and Their Relevance Today

    DTIC Science & Technology

    2013-04-19

    37 7 Preface As a logistics officer, I am naturally inclined to see military...providing a stabilizing presence, conducting humanitarian assistance and disaster response, and deterring and defeating aggression.5 These missions will...Context In retrospect, it is tempting to consider the underway replenishment of seagoing vessels and the advanced base concept as a natural

  3. Robust Intelligence (RI) Under Uncertainty: Mathematical Foundations of Autonomous Hybrid (Human-Machine-Robot) Teams, Organizations and Systems

    DTIC Science & Technology

    2013-01-01

    seeds of chaos. Stability and internal peace bring prosperity; prosperity causes population increase. Demographic growth leads to overpopulation ... overpopulation causes lower wages, higher land rents, and falling per-capita incomes … [Eventually, the] collapse of order brings … famine, war...one of the most innovative, competitive and largest firms in the world (e.g., Investors Business Daily, 2000, 10/31; Bloomberg’s Businessweek, 2001, 9

  4. World War II, post-war reconstruction and British women chemists.

    PubMed

    Horrocks, Sally

    2011-07-01

    This paper draws on evidence from a range of sources to consider the extent to which World War II served as a turning point in the employment opportunities open to women chemists in Britain. It argues that wartime conditions expanded women's access to some areas of employment, but that these opportunities represented, in many ways, an expansion of existing openings rather than wholly new ones, and not all of them proved permanent. Instead, women chemists benefited more permanently from increased state expenditure on higher education and on research and development after the war. This enabled some women to remain in what had originally been temporary wartime posts and others to secure employment in wholly new positions. Women were most successful in securing positions created by the expansion of state welfare and support for agriculture, but also found new employment opportunities as a result of the heavy investment in weapons development that accelerated with the advent of the Cold War. In higher education, an initial expansion of openings was not sustained, and the proportion of women in university chemistry departments actually fell during the second half of the 1950s. Industry presents a rather ambiguous picture, with many firms continuing to refuse to employ women chemists, whereas elsewhere they enjoyed enhanced opportunities and better salaries than those offered before the war. This did not mean, however, that women chemists received equal treatment to their male colleagues, and, despite the changes, they remained concentrated in subordinate positions and were expected to concentrate on routine work. Prospects in the 1950s were certainly better than they had been during the 1930s, but they remained strongly gendered.

  5. Defying the activity-stability trade-off in enzymes: taking advantage of entropy to enhance activity and thermostability.

    PubMed

    Siddiqui, Khawar Sohail

    2017-05-01

    The biotechnological applications of enzymes are limited due to the activity-stability trade-off, which implies that an increase in activity is accompanied by a concomitant decrease in protein stability. This premise is based on thermally adapted homologous enzymes where cold-adapted enzymes show high intrinsic activity linked to enhanced thermolability. In contrast, thermophilic enzymes show low activity around ambient temperatures. Nevertheless, genetically and chemically modified enzymes are beginning to show that the activity-stability trade-off can be overcome. In this review, the origin of the activity-stability trade-off, the thermodynamic basis for enhanced activity and stability, and various approaches for escaping the activity-stability trade-off are discussed. The role of entropy in enhancing both the activity and the stability of enzymes is highlighted with a special emphasis placed on the involvement of solvent water molecules. This review is concluded with suggestions for further research, which underscores the implications of these findings in the context of productivity curves, the Daniel-Danson equilibrium model, catalytic antibodies, and life on cold planets.

  6. Bridging psychological barriers between the child and the father after his returning from the war: Could group art therapy help?

    PubMed

    Mandić-Gajić, Gordana

    2016-07-01

    War veterans with chronic post-traumatic stress disorder (PTSD) have poorer family and parenting functioning, but little research has focused on these impairments. This paper presented how the series of drawings and the group art therapy process enhanced bridging the psychological barriers of a 33-year-old male PTSD war veteran to engagement with the child. After two years of deployment he returned home and suffered mostly from PTSD numbness and avoidance symptoms. The veteran had the family readjustment difficulties and felt guilty for being detached from his 3-year-old son. He under-went integrative treatment in the Day Unit Program. The drawings series were made by free associations. Clinical observations and group discussions were recorded in the group art therapy protocols. The presented patient got gratifications and support from the group members for his illustration of popular cartoon heroes, and decided to draw Mickey Mouse at home. On the next session he shared his satisfaction for bridging the gap between him and his son, having done the same drawings with his son at home. Beck's depression inventory (BDI) was used for self-rating of depression and a reduction of BDI score from 18 to 6 during the treatment course was recorded. Series of drawings illustrated shift from war related past toward current family life of the war veteran. Group art therapy gave him gratification and support with hope and a sense of belonging, thus facilitated his parenting readjustment.

  7. Aid in a city at war: the case of Mogadishu, Somalia.

    PubMed

    Grünewald, François

    2012-07-01

    Mogadishu, the capital of Somalia, has been central to life, war, and peace in the country for almost two decades. Its urban characteristics, though, have been put to one side for the most part. In recent years, Mogadishu-related issues have been merged mostly into a global agenda for South and Central Somalia, resulting in the technical and coordination approaches employed in the city largely being reproductions of solutions utilised in refugee camps and rural areas. Unfortunately, urban problems require urban solutions. The aid system is just starting to discover how specific aid in cities at war should be, both from an organisational and a technical standpoint. The enhancement of aid practices in an urban setting implies, among other things, a more strategic approach to the specific spatial characteristics of the city, a more fine-tuned analysis of the technical requirements of the urban service delivery systems, and a better understanding of the role of urban institutions. © 2012 The Author(s). Journal compilation © Overseas Development Institute, 2012.

  8. 100 million refugees. The world stabilizes through population stability.

    PubMed

    Sakaiya, T

    1993-09-01

    Global change has come about due to shifts in the business cycle, a new undeveloped paradigm to replace the Cold War, and a stabilization of expansion and development of modern industrial society. Japan has been transfixed with its own internal domestic affairs, but will feel the consequences of the Industrial Age nearing its end. Industrialization had relied on unlimited resources from the natural environment and the belief that a free-market economy would automatically lead to orderliness and a state of economic equilibrium. Population control has been an issue that has slid over the years as a priority status. In 1800, the population in developed countries was 4 times the population in developing countries; the reverse is becoming true. Mass migration was an unusual phenomena and not the problem it is today. There is a gap between population and productive capacity. Developed countries believed in humanitarian aid for refugees and impoverished peoples, but the numbers were unanticipated. There is no shame for war or civil unrest to drive boat people and hugh numbers to another country. The notion of nation state has changed. The boat people from Cuba were a beginning example of how governments were unconcerned about the loss of population. Afghanistan in 1979 was another example of refugees fleeing civil war. Iraq bombed the Kurds until there was no choice but to leave. Turkey was required to use troops to drive the Kurds back into Iraq. To increase aid indefinitely, or to send out more refugees than it takes in, or to use military forces to kill the invading refugees are not acceptable. An international framework with consensus from developed and developing countries is needed for dealing with mass migrations. Conventions adopted would have to be recognized as in each countries self-interest; disregard of the regulations would have to reflect significant disadvantages to a nation. Several issues are discussed as key in such a global framework: assuring productivity for all by absorbing some refugees, and developing new training programs for the private sector at home, and assuring development aid (technology, capital, markets). A self perpetuating cycle of growth and expansion must be set in motion. Infrastructure development must be replaced with stable employment in the home country.

  9. History of internal fixation with plates (part 2): new developments after World War II; compressing plates and locked plates.

    PubMed

    Hernigou, Philippe; Pariat, Jacques

    2017-07-01

    The first techniques of operative fracture with plates were developed in the 19th century. In fact, at the beginning these methods consisted of an open reduction of the fracture usually followed by a very unstable fixation. As a consequence, the fracture had to be opened with a real risk of (sometimes lethal) infection, and due to unstable fixation, protection with a cast was often necessary. During the period between World Wars I and II, plates for fracture fixation developed with great variety. It became increasingly recognised that, because a fracture of a long bone normally heals with minimal resorption at the bone ends, this may result in slight shortening and collapse, so a very rigid plate might prevent such collapse. However, as a consequence, delayed healing was observed unless the patient was lucky enough to have the plate break. One way of dealing with this was to use a slotted plate in which the screws could move axially, but the really important advance was recognition of the role of compression. After the first description of compression by Danis with a "coapteur", Bagby and Müller with the AO improved the technique of compression. The classic dynamic compression plates from the 1970s were the key to a very rigid fixation, leading to primary bone healing. Nevertheless, the use of strong plates resulted in delayed union and the osteoporosis, cancellous bone, comminution, and/or pathological bone resulted in some failures due to insufficient stability. Finally, new devices represented by locking plates increased the stability, contributing to the principles of a more biological osteosynthesis while giving enough stability to allow immediate full weight bearing in some patients.

  10. Enhancing the performance of tungsten doped InZnO thin film transistors via sequential ambient annealing

    NASA Astrophysics Data System (ADS)

    Park, Hyun-Woo; Song, Aeran; Kwon, Sera; Choi, Dukhyun; Kim, Younghak; Jun, Byung-Hyuk; Kim, Han-Ki; Chung, Kwun-Bum

    2018-03-01

    This study suggests a sequential ambient annealing process as an excellent post-treatment method to enhance the device performance and stability of W (tungsten) doped InZnO thin film transistors (WIZO-TFTs). Sequential ambient annealing at 250 °C significantly enhanced the device performance and stability of WIZO-TFTs, compared with other post-treatment methods, such as air ambient annealing and vacuum ambient annealing at 250 °C. To understand the enhanced device performance and stability of WIZO-TFT with sequential ambient annealing, we investigate the correlations between device performance and stability and electronic structures, such as band alignment, a feature of the conduction band, and band edge states below the conduction band. The enhanced performance of WIZO-TFTs with sequential ambient annealing is related to the modification of the electronic structure. In addition, the dominant mechanism responsible for the enhanced device performance and stability of WIZO-TFTs is considered to be a change in the shallow-level and deep-level band edge states below the conduction band.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Helms, C.M.

    Iraq, holding oil reserves second only to those of Saudi Arabia in the Middle East, is locked in a war with Iran whose outcome will affect Western energy supplies and the prospects for stability in the Arabian Gulf. Yet Iraq even now remains little known to Western governments and publics. This study is intended to enlarge understanding of Iraqi behavior and of the concerns that motivate its leaders. Rather than selecting issues of importance to other countries, the author focuses on the forces that influence policy formulation in Iraq and evokes the perspective from which the Iraqi government itself viewsmore » its problems and sets its priorities. Part 1 examines the country's evolution into modern Iraq, explaining why problems that have recurred throughout Iraqi history have bedeviled all recent Iraqi governments and created tension between ''Iraq the nation'' and ''Iraq the state.'' Part 2 discusses the Arab Ba'th Socialist party, which has dominated Iraqi political life since 1968. The author neither condemns nor praises this controversial party and its current leader, President Saddam Husain, but seeks to explain why they have adopted the positions and taken the actions that have characterized their rule. Part 3 analyzes the war between Iraq and Iran, its causes, and the decisions Iraq has made in light of its goals and its assumptions about Iran. The author finds that this is not simply ''a war over borders'' but a deeper conflict between Islamic conservatism and Arab nationalism. Looking beyond the war, the final chapter assesses Iraq's potential importance in the Middle East and to the world economy. 8 figs.« less

  12. The troublesome birth of hydrodynamic stability theory: Sommerfeld and the turbulence problem

    NASA Astrophysics Data System (ADS)

    Eckert, M.

    2010-07-01

    More than a hundred years ago William McFadden Orr and Arnold Sommerfeld conceived an approach to account for the transition from laminar to turbulent flow in terms of hydrodynamic stability theory. But the “turbulence problem”, as this challenge became notoriously famous, could not be solved by this method. By 1920, it was widely recognized as an outstanding riddle. Although famous theoretical physicists like Werner Heisenberg dedicated a considerable effort to this problem, the “Orr-Sommerfeld method” has never found the attention of historians of science. This article describes its early perception and development in Germany, and how the “turbulence problem” reached center stage after the First World war as a major challenge for theorists with different perspectives.

  13. SIOP for Perestroika. Research report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Szafranski, R.

    1990-04-01

    The pursuit of greater stability through arms reductions is an important component of perestroika. Assuming strategic weapons reductions, the general nuclear war plan, the Single Integrated Operational Plan (SIOP), will change to employ fewer nuclear arms. If stability and threat reduction are authentic goals, the composition of nuclear offensive forces and the SIOP alert force will evolve accordingly. Greater reliance will likely be placed on bombers. The United States and the Soviet Union can use the opportunity provided by perestroika to agree that the only legitimate role of nuclear weapons is to deter nuclear weapons by threatening nuclear reprisal ormore » punishment. Both sides can then share a strategic catechism that would allow them to move toward small reprisal forces.« less

  14. Insomnia in a displaced population is related to war-associated remembered stress.

    PubMed

    Basishvili, Tamar; Eliozishvili, Marine; Maisuradze, Lia; Lortkipanidze, Nani; Nachkebia, Nargiz; Oniani, Tengiz; Gvilia, Irma; Darchia, Nato

    2012-08-01

    Although traumatic events are presumed to cause sleep disturbances, particularly insomnia, sleep in populations subjected to forced displacement has received little attention. The present study examined the prevalence of insomnia and associated factors in internally displaced persons (IDPs) from Abkhazia 15 years after displacement to Tbilisi. Detailed subjective information about sleep-wake habits, sleep-related and stress-related parameters were obtained from 87 IDPs categorized into good sleepers and insomniacs. The Insomnia Severity Index, Perceived Stress Scale and Beck Depression Inventory were administered. The incidence of insomnia was 41.4%. The majority of insomniacs strongly believed that war-related stress accounted for the onset of their insomnia. Stepwise regression (95% confidence interval) revealed four variables significantly associated with insomnia status: self-estimated influence of war related stress (odds ratio (OR) = 2.51), frequency of nightmares (OR = 1.6), Perceived Stress Scale score (OR = 1.14) and Beck Depression Inventory score (OR = 1.12). Insomnia in IDPs was strongly related to war-associated remembered stress. ‛Over thinking' about major stress exposure enhanced IDPs' vulnerability to insomnia. These findings have implications for the management of insomnia and associated impairment of daytime functioning in IDPs. Copyright © 2011 John Wiley & Sons, Ltd.

  15. The new front in the war on doping: Amateur athletes.

    PubMed

    Henning, April D; Dimeo, Paul

    2018-01-01

    The war on drugs is usually associated with criminal policies aimed at stemming consumption of drugs such as heroin, cocaine, and cannabis, less so with enhancement drugs like those used in sport. As drug use in sport, or doping, has become more visibly widespread, policies aimed at combating the issue have become more restrictive, intrusive, and harsh. In this article we draw new comparisons between the wider war on drugs and recent developments in sports anti-doping. We identify a growing trend towards criminalisation of traffickers and users, and associate that with another growing trend: the testing of amateur athletes. This article reviews the current anti-doping system, including the recent amateur policies, then considers of the results of one such program in amateur cycling. We then shift to consider the possible implications for amateurs of criminal doping laws and the recent debates about allowing medical exemptions for therapeutic use of banned substances. We show that drug use in sport can be understood as a new front in the war on drugs, with some extreme measures and many negative unintended consequences. To remedy this, we argue that amateur athletes require a separate anti-doping policy focused on minimising harms of use. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Nuclear winter - Global consequences of multiple nuclear explosions

    NASA Technical Reports Server (NTRS)

    Turco, R. P.; Toon, O. B.; Ackerman, T. P.; Pollack, J. B.; Sagan, C.

    1983-01-01

    The results of a computerized simulation of the potential global environmental effects of dust and smoke clouds that would be generated by a nuclear war are presented. Short term effects of blast, fire, and radiation are neglected in the series of physical models that include a nuclear war scenario, a particle microphysics model, and a radiative convective model. Account is taken of the altitude-dependent dust, smoke, radioactivity, and NO(x) injections, the temporal evolution of dust and smoke clouds, land and ocean environments, and temperature contrasts. A nuclear exchange would produce thousands of individual smoke and dust clouds rising up to 30 km altitude in the midlatitudes. The smoke, dust, and radioactive debris would cover the entire midlatitudes within 1-2 weeks. The smoke would arise from conflagrations of forests, suburbs, and urban areas. Obscuration of sunlight would induce subfreezing temperatures for several months, disruption of the global circulation patterns, and the arrival of a nuclear winter, followed and accompanied by radioactive fallout, pyrogenic air pollution, and UV-B flux enhancements. It is estimated that a total of only 100 Mtons would be sufficient to plunge the Northern Hemisphere summer to subfreezing temperatures lasting months. Since the probable exchange in a nuclear war would exceed 5000 Mtons, it is expected that many species, including humans, may not survive the war.

  17. Submarine and Autonomous Vessel Proliferation: Implications for Future Strategic Stability at Sea

    DTIC Science & Technology

    2012-12-01

    missile.4 These important details of the legacy of the Cold War at sea are too often forgotten in today’s retelling of the story . Yet, as CDR (USN...vented deadly fumes. The damaged and still-burning vessel was scuttled with its nuclear weapons and reactors aboard. 8 Pavel Podvig, ed., Russian ...exception of China in the 1950s,13 the Russians generally did not provide production technology and refrained from offering sophisticated offensive systems

  18. Implications of China’s Growing Military Diplomatic Clout for the United States: Cooperation, Competition or Conflict

    DTIC Science & Technology

    2009-03-01

    conflicts and wars; • Stands for effective disarmament and arms control that are just, reasonable, comprehensive and balanced in nature; • Opposes nuclear ...proliferation, and endeavors to advance the process of international nuclear disarmament; • Observes the purposes and principles of the UN Charter... disaster relief operations; and • Plays an active part in maintaining global and regional peace and stability.16 The CPC, Foreign Ministry, and

  19. Journal of Rehabilitation Research and Development - Winter 1992. Volume 29, Number 1, 1992

    DTIC Science & Technology

    1992-01-01

    in El Salvador (1985), was the early use of internal causes of injury, following "soldiering activity" fracture stabilization in open war wounds. Now...soft from activities such as: anti-tank warfare, grenades, tissue wound healing and provided for fracture helicopter accidents, cluster bombs, mortar...sur- Of the injured cared for at LARMC (444), gery, is an area of surgical medicine which has there were 194 open fractures , 49 meniscal injuries

  20. Strategic Studies Quarterly. Volume 5, Number 1, Spring 2011

    DTIC Science & Technology

    2011-01-01

    2010). 17. The White House, National Space Policy of the United States of America (Washington: White House, 28 June 2010), 3. 18. John Oneal and Bruce... censors and vigilantes) model operating on many levels at once. In this model, China is expressing a long-standing concern for the stability and...Ansfield, “China’s Censors Tackle and Trip Over the Internet,” New York Times, 8 April 2010. 32. Ching Cheong, “Fighting the Digital War with the

  1. Revolution or Realism? United States-Iran Relations in the Post-Cold War Era

    DTIC Science & Technology

    1993-12-01

    to mirror the American situation. 27 Tho wirhdawal of Soviet forces from Afghanistan, the subsequent disintegration of the Soviet Union, and the... Kozyrev met with Rafsanjani in Tehran in March. The purpose of the visit was apparently to increase bilateral economic and strategic ties in order to...strengthen stability in Central Asia. Kozyrev also said his task was to demonstrate Moscow’s support for the presidents reforms. "There is no doubt that

  2. Lebanon: The Israel-Hamas Hezbollah Conflict

    DTIC Science & Technology

    2006-09-15

    cut across a number of U.S. policy issues in the Middle East. This report provides an assessment of the month-long war and its implications for...regional stability and other key U.S. policy issues . This report will be updated periodically. A number of CRS analysts have contributed to this report. For...RL33487, Syria: U.S. Relations and Bilateral Issues ; CRS Report RL32048, Iran: U.S. Concerns and Policy Responses; and CRS Report RL33530, Israeli

  3. The Trilateral Force: The Atlantic Alliance and the Future of Nuclear Weapons Strategy

    DTIC Science & Technology

    2013-01-01

    2010), 10. 4 Robert Manning, Envisioning 2030: U.S. Strategy for a Post-Western World, Atlantic Council (2013), 46. 5 Paul Bracken, The Second...Strategic Stability: Contending Interpretations, U.S. Army War College Strategic Studies Institute (2013); Paul Bracken, “The Bomb Returns for a Second...U.S. Nuclear Strategy, Force Structure and Posture, Global Zero (2012), 6. 27 Dana Johnson, et al., “Triad, Dyad, Monad? Shaping the U.S. Force of

  4. Protecting Interests and Preventing War: An Analysis of PACAF Force Posture Alternatives

    DTIC Science & Technology

    2015-05-01

    The overall goal was to maintain US leadership in the region and to ensure stability and economic prosperity. Nye claimed, “Our national interests...Kadena Air Base, Okinawa, was perfectly situated to influence events in Taiwan and the East China Sea, but its runways and other key facilities were...Army and Marine forces was extremely risky. America faced major power-projection problems in a key economic region, while China began a period of

  5. Insights into Appreciation and Learning Systems

    NASA Astrophysics Data System (ADS)

    Vickers, Geoffrey

    [. . .] I grew to manhood before the FirstWorldWar in an England that took stability for granted and regarded order - national and international - both as a self-regulating process of betterment called progress and also as a field for human design directed to the same end. These two not wholly consistent ideas applied in the political-social, the financial-economic, and the scientific-technological fields; all these fields are regarded as benign partners, the first still the most prized.

  6. The Civilian Uplift and Unified Action: Organizing for Stability Operations in Regional Command-East

    DTIC Science & Technology

    2012-03-01

    Intelligence Relevant in Afghanistan,”18 began sending capabilities to SOIC –East to flesh out the organization , and provided guidance for synthesizing...military organizations throughout the area of operations. This “civilian uplift” represented the largest deployment of U.S. agencies to a combat zone since...the Vietnam War.1 The CJTF–82/RC–E headquarters was organized around the headquarters, tactical opera- tions centers, and the special troops

  7. Salience of the Nuclear Threat: Operationalization through Spontaneous Concern.

    ERIC Educational Resources Information Center

    Mayton, Daniel M., II

    An indirect/nonreactive technique of assessing spontaneous concern should be used to examine the salience of the threat of nuclear war. Direct/reactive techniques may produce inconsistent results and inadvertently enhance a false consensus. The procedures for the administration, scoring, and interpretation of a spontaneous concern measure along…

  8. The Woman's Land Army: 1918-1920.

    ERIC Educational Resources Information Center

    Laughlin, Margaret

    1994-01-01

    Describes the origins and work of the Women's Land Army, a World War I British volunteer agricultural production unit. Details similar program in the United States. Identifies the impact of the Women's Land Army including enhanced political, economic, and physical freedom for the participants and future generations of women. (CFR)

  9. A Modern City--Its Geography.

    ERIC Educational Resources Information Center

    Mayer, Harold M.; And Others

    This publication contains nine articles intended to enhance teachers' understanding of urban geography. The articles are reprinted from issues of the 1969 volume of the Journal of Geography. Urban studies has been one of the most rapidly developing fields of geography during the post World War II generation. There has been extensive research and…

  10. From Containment to Integration: A Grand Strategy for the 21st Century

    DTIC Science & Technology

    2006-03-06

    Under the theory that democracies do not go to war with each other, an assertion first made by Immanuel Kant and echoed by President Bush; George W...nations and societies under the belief that promotion of democracy enhances the security of the United States, if one accepts the Kantian premise that...world would enhance U.S. security under the Kantian rubric, current conditions for much of the populations of those areas is more Hobbesian – short and

  11. Tuneable enhancement of the salt and thermal stability of polymeric micelles by cyclized amphiphiles

    PubMed Central

    Honda, Satoshi; Yamamoto, Takuya; Tezuka, Yasuyuki

    2013-01-01

    Cyclic molecules provide better stability for their aggregates. Typically in nature, the unique cyclic cell membrane lipids allow thermophilic archaea to inhabit extreme conditions. By mimicking the biological design, the robustness of self-assembled synthetic nanostructures is expected to be improved. Here we report topology effects by cyclized polymeric amphiphiles against their linear counterparts, demonstrating a drastic enhancement in the thermal, as well as salt stability of self-assembled micelles. Furthermore, through coassembly of the linear and cyclic amphiphiles, the stability was successfully tuned for a wide range of temperatures and salt concentrations. The enhanced thermal/salt stability was exploited in a halogen exchange reaction to stimulate the catalytic activity. The mechanism for the enhancement was also investigated. These topology effects by the cyclic amphiphiles offer unprecedented opportunities in polymer materials design unattainable by traditional means. PMID:23481382

  12. Housing the Citizen-Consumer in Post-war Britain: The Parker Morris Report, Affluence and the Even Briefer Life of Social Democracy.

    PubMed

    Kefford, Alistair

    2018-06-01

    This article examines debates about the design and provision of post-war housing within the papers and report of the Parker Morris committee. It does so to show how the models of citizens' rights and expectations which underpinned post-war welfare provision were transformed by mass affluence and the dynamic sphere of commercial consumption. Parker Morris's deliberations demonstrate that, as early as the 1950s, the citizen-subject was reimagined as a consuming individual, with requirements based on their expressive needs and consuming desires, and that this had far-reaching consequences for social democratic systems of universal welfare provision. The introduction of consumerist imperatives into publicly defined models of citizens' needs enhanced the political and cultural authority of the commercial domain, prompted a heightened role for commercial experts and market logics within public governance, and served to devalue socialized forms of provision in favour of consumer choice in the private market. The article thus engages with the growing scholarship on the politics of mass consumerism by showing how the material and emotional comforts of post-war affluence came to be constructed as critical to social democratic citizenship and selfhood. Situating this uneasy entanglement of social democratic rights with consumer satisfaction as part of a wider trajectory of political change, the piece suggests that Parker Morris marks an early but significant moment in the transition from post-war welfarism and social democracy to the consumer- and market-oriented forms of governance which came to dominate British politics and society in the latter part of the twentieth century.

  13. Petite Guerre: Brigadier General George Cook, Commander of the Department of Arizona, Application of Small War Doctrine Against the Apache 1870-1873

    DTIC Science & Technology

    2014-05-22

    31John Bourke , The Diaries of John Gregory Bourque November 20, 1872 thru July 28, 1876, 2nd ed. (Denton: University of North Texas Press, 2003), 19. In...his diaries, Bourke captures official correspondence between Crook and his higher headquarters specifically cited is his correspondence with AAG...1876). Bourke captures Crooks’ response to higher headquarters about going on the offensive against hostiles to create stability the in the area of

  14. The Joint Chiefs of Staff and National Policy: 1965-1968 (History of the Joint Chiefs of Staff)

    DTIC Science & Technology

    2012-01-01

    Johnson was under fire from "doves" on the left who had turned against the Vietnam War and "hawks" on the right who claimed that stronger action... resisting a major assault in Europe. In addition, conduct specialized counterinsurgency operations or a stabilizing action, as in the Dominican...unprotected, 120-140 SLBM tubes which were mostly short-range and surface- fired , and about 200 heavy bombers.2 Secretary McNamara planned to level

  15. Searching for Stability: The U.S. Development of Constabulary Forces in Latin America and the Philippines

    DTIC Science & Technology

    2010-01-01

    Receiverships in Haiti and the Dominican Republic.3 The Navy ran the Virgin Islands until 1931, Guam until 1950, and Ameri- can Samoa until 1951...in Puerto Rico, at both ends of the Canal Zone in Panama, at Guantanamo Bay in Cuba, and in the Virgin Islands. In addition, interest was...Panamanian holiday island of Taboga. Panama quickly followed the US lead in declaring war on the Central Powers, but its major role was harassing resident

  16. Civilian Skills for African Military Officers to Resolve the Infrastructure, Economic Development, and Stability Crisis in Sub-Saharan Africa

    DTIC Science & Technology

    2011-03-01

    AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Army War College,Strategic... projects build - ing Chinese infrastructure in both rural and urban ar- eas.53 The Chinese model thus instills a lifelong dedica- tion to and...Studies Institute,122 Forbes Avenue,Carlisle,PA,17013 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES

  17. Transition Delay in Hypervelocity Boundary Layers by Means of Vibrational Relaxation and Acoustic Instability Interactions

    DTIC Science & Technology

    2014-01-04

    Ca, 93536 Stuart Laurence2, Amy War-Kei Beierholm3, Hans G. Hornung4 Caltech, Pasadena, Ca, 91125 and Ross Wagnild5, Graham Candler6 University...The shots refer to particular conditions tested in the T5 facility for a 45-degree swept cylinder. Taken from [10]. The theory of how relaxation...0. 25 14 /6 .2 00 9- 12 87 27 American Institute of Aeronautics and Astronautics 15 3 Mack, L.M., “Boundary-layer stability theory ,” In

  18. United States Counterinsurgency Doctrine and Implementation in Iraq

    DTIC Science & Technology

    2004-06-18

    combat force until the host nation can stabilize the situation and that, The primary role for US military forces in combat operations is to support...they are to the insurgent as the water is to a fish . Not only does water sustain the life of the fish , it also drowns the enemy. Discipline in the...the populous by building trust and then sharing ideology. Because this process can take time, he makes the point in his Primer on Guerrilla War that

  19. The Influence of Key International Actors (U.S.-E.U.) and Kemalists on Turkey’s Attitude Toward its Kurdish Minority

    DTIC Science & Technology

    2008-06-01

    U.S. relations. Until the fall of the Berlin wall, the Americans viewed Turkey’s political stability and territorial integrity as indispensable to...the aftermath of World War I. Therefore, as Hakan Ozoglu argues, Kurdish nationalism was not a cause, but rather the result of the Empire’s fall .15...especially the British. Lord Curzon, head of the British delegation to Sèvres, was reported arguing that “after enquiries in Constantinople

  20. Building Up a Strategy for De-Balkanizing the Balkans: Stability and Prosperity in South Eastern Europe

    DTIC Science & Technology

    2002-12-01

    Serbian Orthodox church . As a model for fevering nationalist passions served the Serbian medieval Empire of Stephen Dusan. Serbian national sentiment...prominent” was the one at the end of the Great War when, as Austro-Hungary disintegrated in 1918 , Romania being in the Allies’ side entered her armies in...West. This Schism became definitive in 1054 dividing the Christian world into the Roman Catholic and the Greek Orthodox churches . 103 From the

  1. U.S. Stabilization and Reconstruction Doctrine: A Failure to Address the Specifics of Authoritarian Regime Transition

    DTIC Science & Technology

    2009-12-03

    A. Frick U.S. Army School of Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas AY 2009...involvement. The expansion of free markets , the advent of two world wars and the rise of communism shifted U.S. policy to a focus on global leadership...improvements in technology and the expansion of free markets . Free markets , a principle of classical liberalism, slowly pushed America into the global realm

  2. U.S. Stabilization and Reconstruction Doctrine: A Failure to Address the Specifics of Authoritarian Regime Transition

    DTIC Science & Technology

    2009-05-21

    A. Frick U.S. Army School of Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas AY 2009...involvement. The expansion of free markets , the advent of two world wars and the rise of communism shifted U.S. policy to a focus on global leadership...improvements in technology and the expansion of free markets . Free markets , a principle of classical liberalism, slowly pushed America into the global realm

  3. Iraq Stability: Foreign Military Sales in a New War Environment

    DTIC Science & Technology

    2015-05-06

    htlp;/Jwww.bbc.oornlnewsfworld-middle-east-24179084 (accessed September 2, 20 14 ). 13 Michael Knights , "Bringing Iraq’s ’Ghost’ Forces Back to Life... Knights , Michael "Bringing Iraq’s ’Ghost’ Forces Back to Life." Aljazeera.com. http://www .aljazeera.com/indepth/opinion/20 14/ 12/bringing-irag-ghost...VITA Mr. Jamie Jones is a supervisory intelligence officer and serves as U.S. Marine Corps Reserve Middle East Regional Affairs Officer. Jamie has

  4. Fires, A Joint Professional Bulletin for US Field & Air Defense Artillerymen. July-August 07

    DTIC Science & Technology

    2007-08-01

    Zafaraniya area of southeast Baghdad in the Karada Security District. (Photo by SSgt Bronco Suzuki, USAF) The Fires staff wishes to thank RCW...not “cut and run.” External Support. The UN was suc- cessful in stabilizing El Salvador after an exceptionally bloody civil war, in large part by...involving neighboring states that were desperate to keep the conflict from spilling over El Salvador’s borders onto their soil. A family in Northern

  5. Memristor-integrated voltage-stabilizing supercapacitor system.

    PubMed

    Liu, Bin; Liu, Boyang; Wang, Xianfu; Wu, Xinghui; Zhao, Wenning; Xu, Zhimou; Chen, Di; Shen, Guozhen

    2014-08-06

    Voltage-stabilized supercapacitors: A single supercapacitor formed with PCBM/Pt/IPS nanorod-array electrodes is designed and delivers enhanced areal capacitance, capacitance retention, and excellent electrical stability under bending, while a significant voltage-decrease is observed during the discharging process. Once integrated with the memristor, the memristor-integrated supercapacitor systems deliver an extremely low voltage-drop, indicating greatly enhanced voltage-stabilizing features. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. A Quasi-Steady Flexible Launch Vehicle Stability Analysis Using Steady CFD with Unsteady Aerodynamic Enhancement

    NASA Technical Reports Server (NTRS)

    Bartels, Robert E.

    2011-01-01

    Launch vehicles frequently experience a reduced stability margin through the transonic Mach number range. This reduced stability margin is caused by an undamping of the aerodynamics in one of the lower frequency flexible or rigid body modes. Analysis of the behavior of a flexible vehicle is routinely performed with quasi-steady aerodynamic lineloads derived from steady rigid computational fluid dynamics (CFD). However, a quasi-steady aeroelastic stability analysis can be unconservative at the critical Mach numbers where experiment or unsteady computational aeroelastic (CAE) analysis show a reduced or even negative aerodynamic damping. This paper will present a method of enhancing the quasi-steady aeroelastic stability analysis of a launch vehicle with unsteady aerodynamics. The enhanced formulation uses unsteady CFD to compute the response of selected lower frequency modes. The response is contained in a time history of the vehicle lineloads. A proper orthogonal decomposition of the unsteady aerodynamic lineload response is used to reduce the scale of data volume and system identification is used to derive the aerodynamic stiffness, damping and mass matrices. The results of the enhanced quasi-static aeroelastic stability analysis are compared with the damping and frequency computed from unsteady CAE analysis and from a quasi-steady analysis. The results show that incorporating unsteady aerodynamics in this way brings the enhanced quasi-steady aeroelastic stability analysis into close agreement with the unsteady CAE analysis.

  7. History of Astronomy Under the Auspices of the IAU

    NASA Astrophysics Data System (ADS)

    Kochhar, Rajesh; Sun, Xiaochun; Ruggles, Clive; Avilés, Juan Antonio Belmonte; Corbin, Brenda; Milone, Eugene; Norris, Raymond; Oigatto, Luisa; Sōma, Mitsuru

    2016-04-01

    International Astronomical Union was formed after the First World War although it became truly international only after the Second World War. Its Commission 41 on History of Astronomy (C41) was set up in 1948 and in a few years established itself as an active and influential unit. It has the distinction of being a joint Commission, the other partner being International Union of History and Philosophy of Science and Technology (IUHPS). Since IAU is an internationally respected body of professional astronomers, its support for history of astronomy enhances the credibility of the discipline in the eyes of scientists as well as science establishments of individual countries. C41 is committed to advancing objective and rigorous world history of astronomy taking into account all its aspects.

  8. Coping with post-war mental health problems among survivors of violence in Northern Uganda: Findings from the WAYS study.

    PubMed

    Amone-P'Olak, Kennedy; Omech, Bernard

    2018-05-01

    Cognitive emotion regulation strategies and mental health problems were assessed in a sample of war-affected youth in Northern Uganda. Univariable and multivariable regression models were fitted to assess the influence of CERS on mental health problems. Maladaptive cognitive emotion regulation strategies (e.g., rumination) were significantly associated with more mental health problems while adaptive cognitive emotion regulation strategies (e.g., putting into perspective) were associated with reporting fewer symptoms of mental health problems. The youth with significant scores on mental health problems (scores ≥ 85th percentile) reported more frequent use of maladaptive than adaptive strategies. Interventions to reduce mental health problems should focus on enhancing the use of adaptive strategies.

  9. Double-Layer Structured CO2 Adsorbent Functionalized with Modified Polyethyleneimine for High Physical and Chemical Stability.

    PubMed

    Jeon, Sunbin; Jung, Hyunchul; Kim, Sung Hyun; Lee, Ki Bong

    2018-06-18

    CO 2 capture using polyethyleneimine (PEI)-impregnated silica adsorbents has been receiving a lot of attention. However, the absence of physical stability (evaporation and leaching of amine) and chemical stability (urea formation) of the PEI-impregnated silica adsorbent has been generally established. Therefore, in this study, a double-layer impregnated structure, developed using modified PEI, is newly proposed to enhance the physical and chemical stabilities of the adsorbent. Epoxy-modified PEI and diepoxide-cross-linked PEI were impregnated via a dry impregnation method in the first and second layers, respectively. The physical stability of the double-layer structured adsorbent was noticeably enhanced when compared to the conventional adsorbents with a single layer. In addition to the enhanced physical stability, the result of simulated temperature swing adsorption cycles revealed that the double-layer structured adsorbent presented a high potential working capacity (3.5 mmol/g) and less urea formation under CO 2 -rich regeneration conditions. The enhanced physical and chemical stabilities as well as the high CO 2 working capacity of the double-layer structured adsorbent were mainly attributed to the second layer consisting of diepoxide-cross-linked PEI.

  10. Establishment of Institutional Policies for Enhancing Education Quality in Cambodian Universities

    ERIC Educational Resources Information Center

    Rany, Sam; Zain, Ahmad Nurulazam Md; Jamil, Hazri

    2012-01-01

    In the context of global and national economic development, higher education in Cambodia plays a significant role to develop human capital with technical knowledge, skills, values, and attitudes for sustainable economic growth, social development, and alleviation of poverty. When the civil war in 1998 was over, the Royal Government of Cambodia…

  11. Enhanced Cyberspace Defense through Covert Publish-Subscribe Broker Pattern Communications

    DTIC Science & Technology

    2008-06-01

    http://www.cnn.com/TECH/computing/9902/26/t_t/internet.time/, accessed June 2008. [3] C. V. Clausewitz, On War, 1st ed.. London, England: Kegan ...34 2003. [17] T. Greene . (2008 , Apr.) Network World. [Online]. http://www.networkworld.com/news/2008/040908-rsa-hack-power-grid.html, accessed

  12. Post 9/11 Gi Bill: A Proposal for Enhanced Services

    ERIC Educational Resources Information Center

    Bordley-Hughes, Shannon L.

    2018-01-01

    According to the Democratic Staff of the Joint Economic Committee, United States Congress (2017), "over 3.9 million soldiers have served in wartime, since September 11, 2001" ("Gulf War-era II Veterans," para. 1). The Post-9/11 Veterans Assistance Act of 2008 (GI Bill) "offers the 2 million Servicemembers who have served…

  13. Factors that Can Enhance and Limit Resilience for Children of War

    ERIC Educational Resources Information Center

    McAdam-Crisp, Jacqueline L.

    2006-01-01

    This article builds on the author's research in East and Central Africa, specifically Kenya, Rwanda and Ethiopia. It examines minority world resilience theory and explores its application in the majority world, for children in need of protection (CINP). The term "minority world" refers to those in the developed world where the minority…

  14. THE FUTURE OF THE EUROPEAN AIR TRANSPORT COMMAND: AN ANALYSIS OF CAPABILITY ENHANCEMENTS FROM THE ITALIAN AIR FORCE AND AIR MOBILITY COMMAND

    DTIC Science & Technology

    2016-02-15

    25 Bibliography Bowie, Christopher, Fred Frostic, Kevin Lewis, John Lunch, David Ochmanek, and Philip Proppe. The New Calculus : Analyzing...a critical analysis. Carlisle, Pennsylvania: US Army War College, class 2012. Stewart , Rory. The Place in Between. Orlando, FL: Harcourt Books

  15. Mosquito and filth fly control in desert and temperate environments with a synergized pesticide mister and barrier treatment

    USDA-ARS?s Scientific Manuscript database

    U.S. military operations face significant negative impacts on mission readiness from disease-vector and nuisance filth flies, mosquitoes, and sand flies. Through the Deployed War Fighter Protection Program (DWFP) we previously developed small scale 9 ft by 3 ft pesticide-treated perimeters enhanced ...

  16. White matter abnormalities in Gulf War veterans with posttraumatic stress disorder: A pilot study.

    PubMed

    Bierer, Linda M; Ivanov, Iliyan; Carpenter, David M; Wong, Edmund W; Golier, Julia A; Tang, Cheuk Y; Yehuda, Rachel

    2015-01-01

    Gulf War veterans were exposed to environmental toxins not present in other combat theaters resulting in a unique biological signature that only partially resembles that seen in other combat veterans with PTSD. Thus it is important to determine if brain abnormalities seen in non-Gulf War veterans with PTSD are also present in Gulf War veterans. In this pilot study, diffusion tensor imaging (DTI) tractography was used to assess the ultra-structural integrity of fronto-limbic white matter connections in Gulf War veterans with and without PTSD. The effects of chronic multisymptom illness on DTI measures was also evaluated. Subjects were 20 previously studied Gulf War veterans on whom MRIs had been obtained. Mean diffusivity (MD) and fractional anisotropy (FA) were determined for left and right cingulum bundle by DTI tractography and compared in separate analyses for 12 veterans with, and 8 without PTSD. The effect of chronic multisymptom illness and it's interaction with PTSD, were similarly investigated using multivariate ACOVA. Partial correlations were used to test the associations of both DTI indices with PTSD severity and plasma cortisol, controlling for whole brain volume. Significantly lower MD was demonstrated in the right cingulum bundle among Gulf War veterans with PTSD. There were no significant differences in MD or FA in the left cingulum bundle. The presence of chronic multisymptom illness significantly attenuated the PTSD associated decrement in right cingulum MD. Clinician and self-rated PTSD symptom severity scores were significantly associated with reduced MD and increased FA in the right cingulum. Similar associations were observed for 8am plasma cortisol in a subset of participants. The preliminary findings indicate increased structural integrity - supporting enhanced connectivity - between right amygdala and anterior cingulate cortex in PTSD. This effect was strongest among Gulf War veterans without chronic multisymptom illness. The association of both MD and FA in the right cingulum with PTSD severity, and with heightened glucocorticoid responsivity, suggests that these DTI findings are a reflection of current PTSD illness expression. Although based on a small sample, these microstructural observations are consistent with a functional model suggesting increased amygdala responsivity in association with anterior cingulate modulation in PTSD. Copyright © 2014. Published by Elsevier Ltd.

  17. [Medecine, Law, and Knowledge Production about the "Civilized" War in the Long 19th Century].

    PubMed

    Goltermann, Svenja

    2015-01-01

    The aim to 'civilize' warfare accompanied Medicine and International Law ever since the mid-19th century. However, the entanglement of Medicine and Law, crucial for such an endeavour, has not been taken into consideration so far; likewise, the huge importance of medical knowledge for the perception of wars and their ramifications did not garner much attention in historical research. Hence, by focusing on the 'long' 19th century, this paper shows, firstly, that the production of surgical knowledge during warfare aimed at measuring the effects of combat on human bodies in order to develop prognostic medical knowledge for future wars, as well as maintaining the combat strength of soldiers. Moreover, this knowledge production during warfare strived for the enhancement of medical competence in the diagnosis and treatment of wounds in general. Secondly, I show that this medical knowledge was not only relevant for warfare, but also crucial for the design of International Law: it served to nourish the debates among the so called 'civilized' nations about legitimate and illegitimate weaponry and warfare.

  18. Inching toward Armageddon: a psychiatric view.

    PubMed

    Abraham, H D

    1983-01-01

    The existence of thermonuclear arsenals capable of destroying much of humanity takes its origins from, and has an influence on, processes that are largely psychological. The threat to use a single nuclear bomb to resolve contemporary conflict is an anathema in part because complex nation-states did not evolve with surviving a nuclear war in mind. The atomic arms race has proceeded apace because of maladaptive psychological mechanism including denial, distortion, projection, and, most relevantly, the need to enhance bonding within groups by creating stereotypes. One consequence of the arms race is a climate of fear and hopelessness, and especially destructive effect of which is seen in children. The physician's role in the prevention of nuclear war is critical, but divided between contradictory roles. On one hand, the physician is traditionally identified as a non-political advocate of the sick; on the other, as an advocate for the public health. It is this second model that enables physicians most legitimately to work for the prevention of nuclear war and to deal with the psychiatric concomitants of a planet drifting toward disaster.

  19. Inching toward Armageddon: a psychiatric view.

    PubMed Central

    Abraham, H. D.

    1983-01-01

    The existence of thermonuclear arsenals capable of destroying much of humanity takes its origins from, and has an influence on, processes that are largely psychological. The threat to use a single nuclear bomb to resolve contemporary conflict is an anathema in part because complex nation-states did not evolve with surviving a nuclear war in mind. The atomic arms race has proceeded apace because of maladaptive psychological mechanism including denial, distortion, projection, and, most relevantly, the need to enhance bonding within groups by creating stereotypes. One consequence of the arms race is a climate of fear and hopelessness, and especially destructive effect of which is seen in children. The physician's role in the prevention of nuclear war is critical, but divided between contradictory roles. On one hand, the physician is traditionally identified as a non-political advocate of the sick; on the other, as an advocate for the public health. It is this second model that enables physicians most legitimately to work for the prevention of nuclear war and to deal with the psychiatric concomitants of a planet drifting toward disaster. PMID:6636836

  20. Religious moral beliefs as mental health protective factor of war veterans suffering from PTSD, depressiveness, anxiety, tobacco and alcohol abuse in comorbidity.

    PubMed

    Hasanović, Mevludin; Pajević, Izet

    2010-06-01

    Our aim was to investigate is there association between level of religious moral beliefs and severity of PTSD symptoms, depressiion symptoms, anxiety and severity of alcohol abuse we tested 152 war veterans on presence of PTSD, depression symptoms, anxiety, alcohol misuse and level of religious moral beliefs. We used Harvard trauma questionnaire (HTQ), Hopkins Check Scale SBCL 25, check list for alcohol misuse MAST. Subjects were assessed with regard to the level of belief in some basic ethical principles that arise from religious moral values. The score of religious moral belief index was used to correlate with severity of PTSD symptoms, depression symptoms, anxiety and severity of alcohol misuse. Mean age of tested subjects was 40.8 (SD=6.6) years. The score of the moral belief index was negatively correlated to PTSD symptom severity and depressiveness (Pearson's r=-0.325, p<0.001; r=-0.247, p=0.005, respectively). Besides that the score of moral belief index negatively correlated with presented anxiety (Pearson's r=-0.199,p=0.026). Related to severity of tobacco and alcohol misuse we found negative association of these with the moral belief index (Pearson's r=-0.227, p=0.011; r=-0.371, p<0.001, respectively). A higher index of religious moral beliefs in war veterans enables better control distress, providing better mental health stability. It enables post traumatic conflicts typical for combatants' survivors to be more easily overcome. It also causes healthier reactions to external stimuli. A higher index of religious moral beliefs of war veterans provides a healthier and more efficient mechanism of tobacco and alcohol misuse control. In this way, it helps overcoming postwar psychosocial problems and socialization of the personality, leading to the improvement in mental health.

  1. Mobile mental health interventions following war and disaster

    PubMed Central

    Kuhn, Eric; Jaworski, Beth K.; Owen, Jason E.; Ramsey, Kelly M.

    2016-01-01

    Mobile technologies offer potentially critical ways of delivering mental health support to those experiencing war, ethnic conflict, and human-caused and natural disasters. Research on Internet interventions suggests that effective mobile mental health technologies can be developed, and there are early indications that they will be acceptable to war and disaster survivors, and prove capable of greatly increasing the reach of mental health services. Promising mhealth interventions include video teleconferencing, text messaging, and smartphone-based applications. In addition, a variety of social media platforms has been used during and immediately after disasters to increase agility in responding, and strengthen community and individual resilience. Globally, PTSD Coach has been downloaded over 243,000 times in 96 countries, and together with large-scale use of social media for communication during disasters, suggests the potential for reach of app technology. In addition to enabling improved self-management of post-trauma problems, mobile phone interventions can also enhance delivery of face-to-face care by mental health providers and increase the effectiveness of peer helpers and mutual aid organizations. More research is needed to establish the efficacy of mhealth interventions for those affected by war and disaster. Research should also focus on the identification of active elements and core processes of change, determination of effective ways of increasing adoption and engagement, and explore ways of combining the various capabilities of mobile technologies to maximize their impact. PMID:28293610

  2. Mobile mental health interventions following war and disaster.

    PubMed

    Ruzek, Josef I; Kuhn, Eric; Jaworski, Beth K; Owen, Jason E; Ramsey, Kelly M

    2016-01-01

    Mobile technologies offer potentially critical ways of delivering mental health support to those experiencing war, ethnic conflict, and human-caused and natural disasters. Research on Internet interventions suggests that effective mobile mental health technologies can be developed, and there are early indications that they will be acceptable to war and disaster survivors, and prove capable of greatly increasing the reach of mental health services. Promising mhealth interventions include video teleconferencing, text messaging, and smartphone-based applications. In addition, a variety of social media platforms has been used during and immediately after disasters to increase agility in responding, and strengthen community and individual resilience. Globally, PTSD Coach has been downloaded over 243,000 times in 96 countries, and together with large-scale use of social media for communication during disasters, suggests the potential for reach of app technology. In addition to enabling improved self-management of post-trauma problems, mobile phone interventions can also enhance delivery of face-to-face care by mental health providers and increase the effectiveness of peer helpers and mutual aid organizations. More research is needed to establish the efficacy of mhealth interventions for those affected by war and disaster. Research should also focus on the identification of active elements and core processes of change, determination of effective ways of increasing adoption and engagement, and explore ways of combining the various capabilities of mobile technologies to maximize their impact.

  3. The effect of peer support groups on family adaptation from the perspective of wives of war veterans with posttraumatic stress disorder.

    PubMed

    Vagharseyyedin, Seyyed Abolfazl; Gholami, Mojtaba; Hajihoseini, Morteza; Esmaeili, Aliakbar

    2017-11-01

    The aim of this study was to examine the effect of peer group support on family adaptation of wives of war veterans suffering from post-traumatic stress disorder (PTSD). In this randomized controlled trial, 80 wives of war veterans with PTSD were incorporated, and selected participants were randomly assigned into intervention and control groups (n = 40 per group). The intervention group was divided into four subgroups, with each participating in eight weekly based 1.5-hr peer support group sessions and the control group received no intervention. Demographics form and Family Adaptation Scale (FAS) developed by Antonovsky and Sourani (1988) were applied. The total mean scores of family adaptation increased significantly more in the intervention group than in the control group (p = .033). Furthermore, the time × group interaction effects were significant for internal family fit (p = .013) and a combination of both family fit and family community fit (p = .020) dimensions. Nonetheless family fit dimensions mean scores had no significant increase in the intervention group than the control group over time (p = .948). Peer support group can be a useful tool for health care professionals to enhance family adaptation in spouses of war veterans with PTSD. © 2017 Wiley Periodicals, Inc.

  4. Long-term follow-up of unilateral transfemoral amputees from the Vietnam war.

    PubMed

    Dougherty, Paul J

    2003-04-01

    Despite their frequency, few reports exist concerning the initial and long-term consequences of battle-incurred unilateral transfemoral amputations. A retrospective cohort design was used to measure the long-term health of transfemoral battle amputees treated at a single hospital during the Vietnam War. Data collection consisted of medical record abstraction and a follow-up questionnaire that included the SF-36 Health Survey. Forty-six patients responded to the survey an average of 28 years after injury. Compared with the controls, patient responses to the SF-36 were significantly (p < 0.01) less in all categories except Mental Health and Vitality. Forty-three (93.5%) are or have been married. Forty-one (89.1%) are or have been employed an average of 20.1 years. Forty patients (87%) wore a prosthesis an average of 13.5 h/day. Although the patients do relatively well with employment and marriage stability, the low SF-36 scores suggest a significant disability.

  5. Both solubility and chemical stability of curcumin are enhanced by solid dispersion in cellulose derivative matrices.

    PubMed

    Li, Bin; Konecke, Stephanie; Wegiel, Lindsay A; Taylor, Lynne S; Edgar, Kevin J

    2013-10-15

    Amorphous solid dispersions (ASD) of curcumin (Cur) in cellulose derivative matrices, hydroxypropylmethylcellulose acetate succinate (HPMCAS), carboxymethylcellulose acetate butyrate (CMCAB), and cellulose acetate adipate propionate (CAAdP) were prepared in order to investigate the structure-property relationship and identify polymer properties necessary to effectively increase Cur aqueous solution concentration. XRD results indicated that all investigated solid dispersions were amorphous, even at a 9:1 Cur:polymer ratio. Both stability against crystallization and Cur solution concentration from these ASDs were significantly higher than those from physical mixtures and crystalline Cur. Remarkably, curcumin was also stabilized against chemical degradation in solution. Chemical stabilization was polymer-dependent, with stabilization in CAAdP>CMCAB>HPMCAS>PVP, while matrices enhanced solution concentration as PVP>HPMCAS>CMCAB≈CAAdP. HPMCAS/Cur dispersions have useful combinations of pH-triggered release profile, chemical stabilization, and strong enhancement of Cur solution concentration. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Climatic Consequences and Agricultural Impact of Regional Nuclear Conflict

    NASA Astrophysics Data System (ADS)

    Toon, O. B.; Robock, A.; Mills, M. J.; Xia, L.

    2013-05-01

    A nuclear war between India and Pakistan, with each country using 50 Hiroshima-sized atom bombs as airbursts on urban areas, would inject smoke from the resulting fires into the stratosphere.This could produce climate change unprecedented in recorded human history and global-scale ozone depletion, with enhanced ultraviolet (UV) radiation reaching the surface.Simulations with the Whole Atmosphere Community Climate Model (WACCM), run at higher vertical and horizontal resolution than a previous simulation with the NASA Goddard Institute for Space Studies ModelE, and incorporating ozone chemistry for the first time, show a longer stratospheric residence time for smoke and hence a longer-lasting climate response, with global average surface air temperatures still 1.1 K below normal and global average precipitation 4% below normal after a decade.The erythemal dose from the enhanced UV radiation would greatly increase, in spite of enhanced absorption by the remaining smoke, with the UV index more than 3 units higher in the summer midlatitudes, even after a decade. Scenarios of changes in temperature, precipitation, and downward shortwave radiation from the ModelE and WACCM simulations, applied to the Decision Support System for Agrotechnology Transfer crop model for winter wheat, rice, soybeans, and maize by perturbing observed time series with anomalies from the regional nuclear war simulations, produce decreases of 10-50% in yield averaged over a decade, with larger decreases in the first several years, over the midlatitudes of the Northern Hemisphere. The impact of the nuclear war simulated here, using much less than 1% of the global nuclear arsenal, would be devastating to world agricultural production and trade, possibly sentencing a billion people now living marginal existences to starvation.The continued environmental threat of the use of even a small number of nuclear weapons must be considered in nuclear policy deliberations in Russia, the U.S., and the rest of the world.

  7. Climatic Consequences and Agricultural Impact of Regional Nuclear Conflict

    NASA Astrophysics Data System (ADS)

    Robock, Alan; Mills, Michael; Toon, Owen Brian; Xia, Lili

    2013-04-01

    A nuclear war between India and Pakistan, with each country using 50 Hiroshima-sized atom bombs as airbursts on urban areas, would inject smoke from the resulting fires into the stratosphere. This could produce climate change unprecedented in recorded human history and global-scale ozone depletion, with enhanced ultraviolet (UV) radiation reaching the surface. Simulations with the NCAR Whole Atmosphere Community Climate Model (WACCM), run at higher vertical and horizontal resolution than a previous simulation with the NASA Goddard Institute for Space Studies ModelE, and incorporating ozone chemistry for the first time, show a longer stratospheric residence time for smoke and hence a longer-lasting climate response, with global average surface air temperatures still 1.1 K below normal and global average precipitation 4% below normal after a decade. The erythemal dose from the enhanced UV radiation would greatly increase, in spite of enhanced absorption by the remaining smoke, with the UV index more than 3 units higher in the summer midlatitudes, even after a decade. Scenarios of changes in temperature, precipitation, and downward shortwave radiation from the ModelE and WACCM simulations, applied to the Decision Support System for Agrotechnology Transfer crop model for winter wheat, rice, soybeans, and maize by perturbing observed time series with anomalies from the regional nuclear war simulations, produce decreases of 10-50% in yield averaged over a decade, with larger decreases in the first several years, over several regions in the midlatitudes of the Northern Hemisphere. The impact of the nuclear war simulated here, using much less than 1% of the global nuclear arsenal, would be devastating to world agricultural production and trade, possibly sentencing a billion people now living marginal existences to starvation. The continued environmental threat of the use of even a small number of nuclear weapons must be considered in nuclear policy deliberations in Russia, the U.S., and the rest of the world

  8. Successful Stabilization of Graphene Oxide in Electrolyte Solutions: Enhancement of Bio-functionalization and Cellular Uptake

    PubMed Central

    Hong, Bong Jin; Compton, Owen C.; An, Zhi; Eryzazici, Ibrahim; Nguyen, SonBinh T.

    2013-01-01

    Aqueous dispersions of graphene oxide are inherently unstable in the presence of electrolytes, which screen the electrostatic surface charge on these nanosheets and induce irreversible aggregation. Two complementary strategies, utilizing either electrostatic or steric stabilization, have been developed to enhance the stability of graphene oxide in electrolyte solutions, allowing it to stay dispersed in cell culture media and serum. The electrostatic stabilization approach entails further oxidation of graphene oxide to low C/O ratio (~1.03) and increases ionic tolerance of these nanosheets. The steric stabilization technique employs an amphiphilic block copolymer that serves as a non-covalently bound surfactant to minimize the aggregate-induced nanosheets-nanosheet interactions. Both strategies can stabilize graphene oxide nanosheets with large dimensions (>300 nm) in biological media, allowing for an enhancement of >250% in the bioconjugation efficiency of streptavidin in comparison to untreated nanosheets. Notably, both strategies allow the stabilized nanosheets to be readily uptake by cells, demonstrating their excellent performance as potential drug delivery vehicles. PMID:22017285

  9. Enhancement of colour stability of anthocyanins in model beverages by gum arabic addition.

    PubMed

    Chung, Cheryl; Rojanasasithara, Thananunt; Mutilangi, William; McClements, David Julian

    2016-06-15

    This study investigated the potential of gum arabic to improve the stability of anthocyanins that are used in commercial beverages as natural colourants. The degradation of purple carrot anthocyanin in model beverage systems (pH 3.0) containing L-ascorbic acid proceeded with a first-order reaction rate during storage (40 °C for 5 days in light). The addition of gum arabic (0.05-5.0%) significantly enhanced the colour stability of anthocyanin, with the most stable systems observed at intermediate levels (1.5%). A further increase in concentration (>1.5%) reduced its efficacy due to a change in the conformation of the gum arabic molecules that hindered their exposure to the anthocyanins. Fluorescence quenching measurements showed that the anthocyanin could have interacted with the glycoprotein fractions of the gum arabic through hydrogen bonding, resulting in enhanced stability. Overall, this study provides valuable information about enhancing the stability of anthocyanins in beverage systems using natural ingredients. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Double polymer sheathed carbon nanotube supercapacitors show enhanced cycling stability

    NASA Astrophysics Data System (ADS)

    Zhao, Wenqi; Wang, Shanshan; Wang, Chunhui; Wu, Shiting; Xu, Wenjing; Zou, Mingchu; Ouyang, An; Cao, Anyuan; Li, Yibin

    2015-12-01

    Pseudo-materials are effective in boosting the specific capacitance of supercapacitors, but during service their degradation may also be very strong, causing reduced cycling stability. Here, we show that a carbon nanotube sponge grafted by two conventional pseudo-polymer layers in sequence can serve as a porous supercapacitor electrode with significantly enhanced cycling stability compared with single polymer grafting. Creating conformal polymer coatings on the nanotube surface and the resulting double-sheath configuration are important structural factors leading to the enhanced performance. Combining different polymers as double sheaths as reported here might be a potential route to circumvent the dilemma of pseudo-materials, and to simultaneously improve the capacitance and stability for various energy storage devices.Pseudo-materials are effective in boosting the specific capacitance of supercapacitors, but during service their degradation may also be very strong, causing reduced cycling stability. Here, we show that a carbon nanotube sponge grafted by two conventional pseudo-polymer layers in sequence can serve as a porous supercapacitor electrode with significantly enhanced cycling stability compared with single polymer grafting. Creating conformal polymer coatings on the nanotube surface and the resulting double-sheath configuration are important structural factors leading to the enhanced performance. Combining different polymers as double sheaths as reported here might be a potential route to circumvent the dilemma of pseudo-materials, and to simultaneously improve the capacitance and stability for various energy storage devices. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr05978j

  11. Mood and Memory Deficits in a Model of Gulf War Illness Are Linked with Reduced Neurogenesis, Partial Neuron Loss, and Mild Inflammation in the Hippocampus

    PubMed Central

    Parihar, Vipan K; Hattiangady, Bharathi; Shuai, Bing; Shetty, Ashok K

    2013-01-01

    Impairments in mood and cognitive function are the key brain abnormalities observed in Gulf war illness (GWI), a chronic multisymptom health problem afflicting ∼25% of veterans who served in the Persian Gulf War-1. Although the precise cause of GWI is still unknown, combined exposure to a nerve gas prophylaxis drug pyridostigmine bromide (PB) and pesticides DEET and permethrin during the war has been proposed as one of the foremost causes of GWI. We investigated the effect of 4 weeks of exposure to Gulf war illness-related (GWIR) chemicals in the absence or presence of mild stress on mood and cognitive function, dentate gyrus neurogenesis, and neurons, microglia, and astrocytes in the hippocampus. Combined exposure to low doses of GWIR chemicals PB, DEET, and permethrin induced depressive- and anxiety-like behavior and spatial learning and memory dysfunction. Application of mild stress in the period of exposure to chemicals exacerbated the extent of mood and cognitive dysfunction. Furthermore, these behavioral impairments were associated with reduced hippocampal volume and multiple cellular alterations such as chronic reductions in neural stem cell activity and neurogenesis, partial loss of principal neurons, and mild inflammation comprising sporadic occurrence of activated microglia and significant hypertrophy of astrocytes. The results show the first evidence of an association between mood and cognitive dysfunction and hippocampal pathology epitomized by decreased neurogenesis, partial loss of principal neurons, and mild inflammation in a model of GWI. Hence, treatment strategies that are efficacious for enhancing neurogenesis and suppressing inflammation may be helpful for alleviation of mood and cognitive dysfunction observed in GWI. PMID:23807240

  12. A Review of Military Health Research Using a Social-Ecological Framework.

    PubMed

    Lubens, Pauline; Bruckner, Tim A

    2018-05-01

    We aim to contextualize the growing body of research on the sequelae of military service in the wars in Afghanistan and Iraq. We employ a social-ecological (SE) framework for the taxonomy of military health research and classify risk as arising from the individual, family, community, and the institutional levels. We intend for this review to inform enhanced health promotion efforts in military communities. Articles reviewed were extracted from Web of Science, PubMed, and Scopus. Research focused on somatic and psychological sequelae of combat deployment published from 2001-the year the war in Afghanistan began-through the end of 2014. We excluded studies of non-US military personnel, other systematic reviews, meta-analyses, book chapters, and theoretical papers. We examined and summarized the aims, participants, methods, study design, SE framework tier, risk factors, and health outcomes. Studies were categorized according to SE tier, whether they focused on somatic, behavioral, or psychological outcomes, and by risk factor. Of the 352 peer-reviewed papers, 84% focused on war's sequelae on the index military personnel, and 75% focused on mental or behavioral health outcomes-mostly on post-traumatic stress disorder. We find comparatively little research focusing on the family, community, or institutional tiers. We know relatively little about how family and community respond to the return of personnel from combat deployment; how family resources affect the health of returning military personnel; and how a war's persistence presents challenges for federal, state, and local agencies to meet military health-care needs. Such work is especially salient as US troops return home from war-particularly in communities where there are substantial military populations.

  13. Enhanced Physical Stability of Amorphous Drug Formulations via Dry Polymer Coating.

    PubMed

    Capece, Maxx; Davé, Rajesh

    2015-06-01

    Although amorphous solid drug formulations may be advantageous for enhancing the bioavailability of poorly soluble active pharmaceutical ingredients, they exhibit poor physical stability and undergo recrystallization. To address this limitation, this study investigates stability issues associated with amorphous solids through analysis of the crystallization behavior for acetaminophen (APAP), known as a fast crystallizer, using a modified form of the Avrami equation that kinetically models both surface and bulk crystallization. It is found that surface-enhanced crystallization, occurring faster at the free surface than in the bulk, is the major impediment to the stability of amorphous APAP. It is hypothesized that a novel use of a dry-polymer-coating process referred to as mechanical-dry-polymer-coating may be used to inhibit surface crystallization and enhance stability. The proposed process, which is examined, simultaneously mills and coats amorphous solids with polymer, while avoiding solvents or solutions, which may otherwise cause stability or crystallization issues during coating. It is shown that solid dispersions of APAP (64% loading) with a small particle size (28 μm) could be prepared and coated with the polymer, carnauba wax, in a vibratory ball mill. The resulting amorphous solid was found to have excellent stability as a result of inhibition of surface crystallization. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

  14. δ-Catenin Increases the Stability of EGFR by Decreasing c-Cbl Interaction and Enhances EGFR/Erk1/2 Signaling in Prostate Cancer.

    PubMed

    Shrestha, Nensi; Shrestha, Hridaya; Ryu, Taeyong; Kim, Hangun; Simkhada, Shishli; Cho, Young-Chang; Park, So-Yeon; Cho, Sayeon; Lee, Kwang-Youl; Lee, Jae-Hyuk; Kim, Kwonseop

    2018-04-30

    δ-Catenin, a member of the p120-catenin subfamily of armadillo proteins, reportedly increases during the late stage of prostate cancer. Our previous study demonstrates that δ-catenin increases the stability of EGFR in prostate cancer cell lines. However, the molecular mechanism behind δ-catenin-mediated enhanced stability of EGFR was not explored. In this study, we hypothesized that δ-catenin enhances the protein stability of EGFR by inhibiting its lysosomal degradation that is mediated by c-casitas b-lineage lymphoma (c-Cbl), a RING domain E3 ligase. c-Cbl monoubiquitinates EGFR and thus facilitates its internalization, followed by lysosomal degradation. We observed that δ-catenin plays a key role in EGFR stability and downstream signaling. δ-Catenin competes with c-Cbl for EGFR binding, which results in a reduction of binding between c-Cbl and EGFR and thus decreases the ubiquitination of EGFR. This in turn increases the expression of membrane bound EGFR and enhances EGFR/Erk1/2 signaling. Our findings add a new perspective on the role of δ-catenin in enhancing EGFR/Erk1/2 signaling-mediated prostate cancer.

  15. "A Step Away from Complacent Knowing": Reinvigorating Democracy through the Humanities

    ERIC Educational Resources Information Center

    Musil, Caryn McTighe

    2015-01-01

    "A step away from complacent knowing" argues that the humanities have long been understood as enhancing civic life and human intellectual and moral development. At moments when democratic societies seem at risk, however, such as the birth of the new US Republic, the aftermath of World War II, and in the face of an anemic…

  16. Gathering Data from the Field: Personal Communication Device Usage on Site

    ERIC Educational Resources Information Center

    Morris, Ronald V.

    2016-01-01

    This article describes a lesson plan that encouraged the usage of digital tools to enhance inquiry as a key tool in teaching elementary social studies. The lesson revolved around a field trip to the home of Civil War Governor Oliver P. Morton (Centerville, Indiana). The active, investigative, and questioning nature of inquiry in social studies…

  17. A Simulated Learning Environment of History Games for Enhancing Players' Cultural Awareness

    ERIC Educational Resources Information Center

    Shih, Ju-Ling; Jheng, Shun-Cian; Tseng, Jia-Jiun

    2015-01-01

    This research attempted to create the historical context of Southern Taiwan in the late nineteenth century based on the martial art novel "Xiao-Mao" (Pussy) by designing a role-play digital game "Taiwan Epic Game" about the war time; in which, Taiwanese history, geography, and culture are presented in an innovative way with…

  18. Teaching about Pearl Harbor. Curriculum Enhancement Series #1.

    ERIC Educational Resources Information Center

    Shields, Anna Marshall

    These materials consist of sample lesson plans for teaching about the Japanese attack on Pearl Harbor on December 7, 1941, in both U.S. and world history classes. The lesson plans challenge students to examine how current attitudes toward the Japanese may be rooted in World War II and Pearl Harbor. Selected bibliographies on Pearl Harbor, World…

  19. Military pain management in 21st century war.

    PubMed

    Buckenmaier, Chester C; Griffith, Scott

    2010-07-01

    Morphine and other opioid drugs have played a major role in austere environment pain management since the Civil War, particularly in the military. While the pre-eminence and success of such medications is without question, their use is accompanied by significant side effects that are undesirable in the most advanced medical settings, and are potentially devastating in the field environment. Recently, there have been significant improvements in pain care for America's wounded service members, along with a shift in how many care providers view pain management. An increasing number of healthcare providers are seeing pain not merely as a symptom, but as a disease process. In addition to dramatically improving care for wounded service members, the evolution in the military's approach to pain is enhancing care for civilians.

  20. Conflict, sticks and carrots: war increases prosocial punishments and rewards.

    PubMed

    Gneezy, Ayelet; Fessler, Daniel M T

    2012-01-22

    Unlike most species, humans cooperate extensively with group members who are not closely related to them, a pattern sustained in part by punishing non-cooperators and rewarding cooperators. Because internally cooperative groups prevail over less cooperative rival groups, it is thought that violent intergroup conflict played a key role in the evolution of human cooperation. Consequently, it is plausible that propensities to punish and reward will be elevated during intergroup conflict. Using experiments conducted before, during and after the 2006 Israel-Hezbollah war, we show that, during wartime, people are more willing to pay costs to punish non-cooperative group members and reward cooperative group members. Rather than simply increasing within-group solidarity, violent intergroup conflict thus elicits behaviours that, writ large, enhance cooperation within the group, thereby making victory more likely.

  1. Rational Design of Biobetters with Enhanced Stability.

    PubMed

    Courtois, Fabienne; Schneider, Curtiss P; Agrawal, Neeraj J; Trout, Bernhardt L

    2015-08-01

    Biotherapeutics are the fastest growing class of pharmaceutical with a rapidly evolving market facing the rise of biosimilar and biobetter products. In contrast to a biosimilar, which is derived from the same gene sequence as the innovator product, a biobetter has enhanced properties, such as enhanced efficacy or reduced immunogenicity. Little work has been carried out so far to increase the intrinsic stability of biotherapeutics via sequence changes, even though, aggregation, the primary degradation pathway of proteins, leads to issues ranging from manufacturing failure to immunological response and to loss of therapeutic activity. Using our spatial aggregation propensity tool as a first step to a rational design approach to identify aggregation-prone regions, biobetters of rituximab have been produced with enhanced stability by introducing site-specific mutations. Significant stabilization against aggregation was achieved for rituximab with no decrease in its binding affinity to the antigen. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

  2. Magnetoconvection and universality of heat transport enhancement

    NASA Astrophysics Data System (ADS)

    Lim, Zi Li; Chong, Kai Leong; Xia, Ke-Qing

    2017-11-01

    We numerically investigate how a vertical external magnetic field affects the convective flow in a Rayleigh-Benard turbulent convection. We observed an enhancement of heat transport under certain range of the Hartmann number Ha that characterizes the strength of the stabilizing Lorentz force. Heat transport enhancement caused by a stabilizing force is also observed in several other systems. We find that the heat transport behaviour in the present system may also be understood in terms of an interplay between the stabilizing and destabilizing forces of the system and the observed optimum heat transport enhancement can be explained by an optimal coupling between thermal boundary layer and the momentum boundary layer. Therefore, the observed behaviour in magnetoconvection appears to belong to the same universality class of stabilizing-destabilizing (SD) flows reported recently. This work was supported by the Research Grants Council (RGC) of HKSAR (No. CUHK14301115) and a NSFC/RGC Joint Research Project (Ref. N_CUHK437/15).

  3. Stabilization of a protein conferred by an increase in folded state entropy.

    PubMed

    Dagan, Shlomi; Hagai, Tzachi; Gavrilov, Yulian; Kapon, Ruti; Levy, Yaakov; Reich, Ziv

    2013-06-25

    Entropic stabilization of native protein structures typically relies on strategies that serve to decrease the entropy of the unfolded state. Here we report, using a combination of experimental and computational approaches, on enhanced thermodynamic stability conferred by an increase in the configurational entropy of the folded state. The enhanced stability is observed upon modifications of a loop region in the enzyme acylphosphatase and is achieved despite significant enthalpy losses. The modifications that lead to increased stability, as well as those that result in destabilization, however, strongly compromise enzymatic activity, rationalizing the preservation of the native loop structure even though it does not provide the protein with maximal stability or kinetic foldability.

  4. Conflict, famine and the arms trade.

    PubMed

    Judd, F

    1995-01-01

    Armed conflict has had horrendous humanitarian effects, causing 22 million deaths, over 80 per cent of them civilian, since 1945 and resulting today in 19 million refugees and 24 million displaced persons. War results in economic collapse, and high levels of military spending decrease regional stability. Benefits to the producers are limited or negative and developed countries should diversify away from arms production. There is a need for greater awareness in the developed countries, an end to the secrecy besetting the arms trade, and restructuring of the industry. A Code of Conduct governing arms exports is proposed.

  5. Wind-Tunnel Investigation of the Effect of Jet-Motor Operation on Stability

    DTIC Science & Technology

    1944-07-01

    authorized group requiring them for the war effort. They were pre- viously held under a security status but are PPT y»",i««<Hl«d. Some of these reports...gas turbine and le finally ejected as a high- velocity hlgh-tcmperature jet. In general, the diffusion of such e. jet is the result of the...is to remain constant, the decrepse in velocity must be accompanied by an increase in ma3S flow . This means, of course, that part of the fluid in

  6. Anion-conducting polymer, composition, and membrane

    DOEpatents

    Pivovar, Bryan S [Los Alamos, NM; Thorn, David L [Los Alamos, NM

    2011-11-22

    Anion-conducing polymers and membranes with enhanced stability to aqueous alkali include a polymer backbone with attached sulfonium, phosphazenium, phosphazene, and guanidinium residues. Compositions also with enhanced stability to aqueous alkali include a support embedded with sulfonium, phosphazenium, and guanidinium salts.

  7. Anion-conducting polymer, composition, and membrane

    DOEpatents

    Pivovar, Bryan S [Los Alamos, NM; Thorn, David L [Los Alamos, NM

    2009-09-01

    Anion-conducing polymers and membranes with enhanced stability to aqueous alkali include a polymer backbone with attached sulfonium, phosphazenium, phosphazene, and guanidinium residues. Compositions also with enhanced stability to aqueous alkali include a support embedded with sulfonium, phosphazenium, and guanidinium salts.

  8. Anion-conducting polymer, composition, and membrane

    DOEpatents

    Pivovar, Bryan S.; Thorn, David L.

    2010-12-07

    Anion-conducing polymers and membranes with enhanced stability to aqueous alkali include a polymer backbone with attached sulfonium, phosphazenium, phosphazene, and guanidinium residues. Compositions also with enhanced stability to aqueous alkali include a support embedded with sulfonium, phosphazenium, and guanidinium salts.

  9. Anion-Conducting Polymer, Composition, and Membrane

    DOEpatents

    Pivovar, Bryan S.; Thorn, David L.

    2008-10-21

    Anion-conducing polymers and membranes with enhanced stability to aqueous alkali include a polymer backbone with attached sulfonium, phosphazenium, phosphazene, and guanidinium residues. Compositions also with enhanced stability to aqueous alkali include a support embedded with sulfonium, phosphazenium, and guanidinium salts.

  10. Stabilization of Li Metal Anode in DMSO-Based Electrolytes via Optimization of Salt-Solvent Coordination for Li-O 2 Batteries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Bin; Xu, Wu; Yan, Pengfei

    The conventional DMSO-based electrolyte (1 M lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) in DMSO) is unstable against the Li metal anode and therefore cannot be used directly in practical Li-O2 batteries. Here, we demonstrate that a highly concentrated electrolyte based on LiTFSI in DMSO (with a molar ratio of 1:3) can greatly improve the stability of the Li metal anode against DMSO and significantly improve the cycling stability of Li-O2 batteries. This highly concentrated electrolyte contains no free DMSO solvent molecules, but only complexes of (TFSI–)a-Li+-(DMSO)b (where a + b = 4), and thus enhances their stability with Li metal anodes. In addition,more » such salt-solvent complexes have higher Gibbs activation energy barriers than the free DMSO solvent molecules, indicating improved stability of the electrolyte against the attack of superoxide radical anions. Therefore, the stability of this highly concentrated electrolyte at both Li metal anodes and carbon-based air electrodes has been greatly enhanced, resulting in improved cyclic stability of Li-O2 batteries. The fundamental stability of the electrolyte with free-solvent against the chemical and electrochemical reactions can also be used to enhance the stability of other electrochemical systems.« less

  11. Geological and Tectonic Evidence for the Formation and Extensional Collapse of the West Antarctic Plateau: Implications for the Formation of the West Antarctic Rift System and the Transantarctic Mountains

    NASA Astrophysics Data System (ADS)

    Fitzgerald, P. G.; Studinger, M.; Bialas, R. W.; Buck, W.

    2007-12-01

    The Transantarctic Mountains (TAM), the world's longest and highest non-contractional intracontinental mountain belt, define the western boundary of the West Antarctic rift system (WARS). The WARS is a broad region of extended continental lithosphere, ca. 750-1000 km wide, lying dominantly below sea-level. A new model (Bialas et al., 2007), proposes that a region of thickened continental crust and high-standing topography, the "West Antarctic Plateau", underwent extensional collapse to leave a remnant edge representing the proto-TAM. Tectonic and paleogeographic reconstructions indicate the plateau formed inboard of a continental arc along the paleo- Pacific margin of Antarctica, active throughout the Paleozoic until the late Mesozoic. This high-standing region was responsible for confining sediments (Beacon Supergroup) to elongate basins along the length of the TAM. Much of the present region of the WARS has been correlated with the Lachlan Fold belt of southeastern Australia. This belt formed from the Ordovician to Carboniferous during back-arc basin formation associated with slab roll- back with short periods of compression. Convergence along the paleo-Pacific margin, perhaps enhanced by subduction of more buoyant oceanic lithosphere as the Phoenix-Pacific ridge was obliquely subducted, resulted in crustal thickening and formation of high-standing terrain (the plateau). Extensional collapse of the plateau most likely began in the Jurassic during initial rifting between East and West Antarctica, but was mainly accomplished during distributed rifting in the Cretaceous (ca. 105-85) following subduction of the Phoenix-Pacific ridge and prior to the separation of New Zealand from Marie Byrd Land. Continued formation of the TAM continued in the Cenozoic concomitant with extension in the WARS that was localized along its western margin adjacent to the TAM. Glacial erosion in the Oligocene and early-Miocene enhanced peak height in the TAM. In this presentation we discuss the diverse geological, geophysical, thermochronological and tectonic evidence for the West Antarctic Plateau and the implications for the formation of the Transantarctic Mountains.

  12. Rapid stabilization of thawing soils For enhanced vehicle mobility: a field demonstration project

    DOT National Transportation Integrated Search

    1999-02-01

    Thawing soil presents a formidable challenge for vehicle operations cross-country and on unsurfaced roads. To mitigate the problem, a variety of stabilization techniques were evaluated for their suitability for rapid employment to enhance military ve...

  13. Environmental Planning While Deployed: Mission Hindrance or Enhancement?

    DTIC Science & Technology

    2013-01-01

    unsani- tary conditions and close quarters such as dysentery, typhoid fever , pneumonia, and influenza were responsible for DNBI. As early as the...illness such as hepatitis, typhoid fever , plague, malaria, or cholera.7 During Operations Iraqi Freedom and Enduring Freedom from 2001 to 2006...Peloponnesian War, Thucydides documented vomiting, convulsions, painful sores, uncontrollable diarrhea, and extreme fever among Athenians jammed

  14. Validity and Reliability of the 3-E Tool for Evaluating the Curriculum Support Intervention in Uganda

    ERIC Educational Resources Information Center

    Mutto, Milton; Mukasa, Immaculate; Avasi, Victor; Kilibo, Charles; Kamwesigye, Charles; Duku, Tom

    2015-01-01

    This study determined psychometric properties of 3-ET, an instrument specifically designed to track the effects of a curriculum support intervention created to enhance the delivery of the national curriculum in a war zone in Uganda. The instrument was developed through brain storm and expert review before being committed to structural and…

  15. Training Teachers to Build Resilience in Children in the Aftermath of War: A Cluster Randomized Trial

    ERIC Educational Resources Information Center

    Baum, Naomi L.; Cardozo, Barbara Lopes; Pat-Horenczyk, Ruth; Ziv, Yuval; Blanton, Curtis; Reza, Avid; Weltman, Alon; Brom, Danny

    2013-01-01

    Background: There is growing interest in school-based interventions for building resilience in children facing trauma and adversity. Recent studies focus on teacher training as an effective way to enhance resilience in their students, and emphasize the need for additional evidence-based practice. Objective: The aim of this study was to evaluate…

  16. Comprehensive Soldier Fitness: A Vision for Psychological Resilience in the U.S. Army

    ERIC Educational Resources Information Center

    Casey, George W., Jr.

    2011-01-01

    The stress and strain on the U.S. Army's community due to nearly a decade of protracted war is well documented in the press and in scientific literature. In response, the Army's Comprehensive Soldier Fitness (CSF) program is a preventive program that seeks to enhance psychological resilience among all members of the Army community, which includes…

  17. An exploration of reminiscence and post-war European immigrants living in a multicultural aged-care setting in Australia.

    PubMed

    Hodges, Cherie; Schmidt, Rachael

    2009-01-01

    This phenomenological study explores the experiences and perceptions of the telling of life stories of four post-war immigrants living in a multicultural residential aged-care setting in Australia. This study aims to shed light on what participants feel about life stories, and the prospect of involvement in the documentation of their life story in order to provide insight and understanding for optimum programme facilitation and better resident care.Semi-structured interviews were conducted with the four participants. Data were audiotaped and transcribed. Phenomenological methods were used to explicate data.Three main themes emerged: diminution of guilt, social sharing - common bonds and, the urge to 'feel' the past to 'fill' the present. It is apparent that aged survivors of war, and displacement to a new country, feel residual guilt regarding the leaving of their homeland. The prospect of documenting their life stories offers an opportunity to provide an explanation for their decision.Immersion in life stories allows the re-experiencing and sharing of past emotions and sensations. Engagement in occupational reminiscence enhances understanding a person's lived life experience, which adds meaning to one's life. Copyright (c) 2009 John Wiley & Sons, Ltd.

  18. Improving the stability of subnano-MoO3/meso-SiO2 catalyst through amino-functionalization

    NASA Astrophysics Data System (ADS)

    Wang, Jiasheng; Wu, Wenpei; Yang, Qianfan; Wang, Wan-Hui; Bao, Ming

    Subnano-MoO3 clusters (below 1nm) have excellent catalytic activity on oxidative desulfurization (ODS). However, the stability is not very satisfactory due to the leaching of MoO3 during the reaction. To enhance the stability, here we developed a method by grafting NH2 to silica. NH2 could form coordination bond with MoO3, as proved by solid state 1H NMR, which can prevent MoO3 from leaching and thus significantly enhance the stability.

  19. Some socio-economic aspects of population growth in the USSR.

    PubMed

    Simchera, V

    1974-01-01

    This summarizes population trends in the U.S.S.R. since the early 19 00's. On August 9, 1973, the population topped 250 million, almost precisely double that of Russia at the time of the 1st general census in 1897. Since 1922 it had increased by more than 84%. Russia has suffered more population loss in wars than any other country in modern times. The First World War, the Civil War, and the Second World War took a toll of more than 30 million, more than 20 million during the Second World War alone. The extent of these loses can be judged from the following: between 1897 and 1913 the population of Russia increased at the rate of 1.55% per annum or 34.6 million; if this had continued the population would have been at least 182.8 million by the end of 1922. As it was, the population was 136.1 million by 1922 and the hypothetical 182.8 million was not reached until 1952. More than 4/5 of today's population have been born since the October Revolution. Only 43 million were born before the revolution and only 7.5 were born in the last century. The economic base has grown much more rapidly than the population. For the period 1940-1972 the population increased 1.27 times, national income 9.51 times, fixed assets, 8.76 times, industrial production, 13.65 times, agricultural output, 2.14 times, and capital investment 14.52 times. The birthrate has been falling since World War 1 but total population growth has increased steadily. Birthrates have declined from 45.5/1000 in 1913 to 17.8/1000 in 1972 and a slight upturn is seen. It is expected that the birthrate will continue to increase slightly, then stabilize. Much of the population increase has come from significantly reduced mortality rates. 1st and 2nd children now account for 71% of all births. Family allowances, child care, free health care, and other social benefits encourage births while high employment levels for women, a shortage of men in the marriageable age ranges, and late marriages tend to depress the birthrate. The shortage of men is directly the result of the losses during World War 2. Employment opportunities have changed dramatically. The country has gone from a primarily agricultural nation to one in which 80% of the people are working class wage or salary earners. The current problem is closing the urban-rural gap and equalizing population density. 3/5 of the people are town-dwellers. To fight declining population in the villages and in the areas of Siberia and the Far East, new towns and new industrial and cultural centers are being established such as Bratsk, Ust-Ilim, Norilsk, and others.

  20. Amorphous stabilization and dissolution enhancement of amorphous ternary solid dispersions: combination of polymers showing drug-polymer interaction for synergistic effects.

    PubMed

    Prasad, Dev; Chauhan, Harsh; Atef, Eman

    2014-11-01

    The purpose of this study was to understand the combined effect of two polymers showing drug-polymer interactions on amorphous stabilization and dissolution enhancement of indomethacin (IND) in amorphous ternary solid dispersions. The mechanism responsible for the enhanced stability and dissolution of IND in amorphous ternary systems was studied by exploring the miscibility and intermolecular interactions between IND and polymers through thermal and spectroscopic analysis. Eudragit E100 and PVP K90 at low concentrations (2.5%-40%, w/w) were used to prepare amorphous binary and ternary solid dispersions by solvent evaporation. Stability results showed that amorphous ternary solid dispersions have better stability compared with amorphous binary solid dispersions. The dissolution of IND from the ternary dispersion was substantially higher than the binary dispersions as well as amorphous drug. Melting point depression of physical mixtures reveals that the drug was miscible in both the polymers; however, greater miscibility was observed in ternary physical mixtures. The IR analysis confirmed intermolecular interactions between IND and individual polymers. These interactions were found to be intact in ternary systems. These results suggest that the combination of two polymers showing drug-polymer interaction offers synergistic enhancement in amorphous stability and dissolution in ternary solid dispersions. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

  1. The enhanced anti-tissue adhesive effect of injectable pluronic-HA hydrogel by poly(γ-glutamic acid).

    PubMed

    Kim, Manse; Hwang, Youngmin; Tae, Giyoong

    2016-12-01

    The stability of tissue barrier in physiological condition is a key factor to isolate the damaged site from adjacent tissue for anti-tissue adhesion. Although pluronic or pluronic-hyaluronic acid (HA) hydrogel as an injectable formulation can prevent tissue adhesion at the injection site, the anti-tissue adhesion effect is limited due to its poor stability. Herein, we prepared tissue barrier formulations composed of pluronic F127 (F127) and HA mixture (F127-HA) and the effect of the addition of poly(γ-glutamic acid) (PGA) was characterized. All of F127, HA, and F127-HA mixture showed the poor in vitro residence stability less than 3 days. However, by adding PGA into F127-HA mixture, their stability was significantly enhanced by the control of the molecular weight and concentration of PGA. Thus, F127-HA with 10wt% PGA (2000kDa) showed the long-term stability over 10 days. Similarly, the enhanced stability of F127-HA with PGA resulted in the enhanced and excellent in vivo anti-tissue adhesion effect, evidenced by histological analysis and grading of tissue adhesion. Therefore, F127-HA containing PGA could be applied as an efficient injectable tissue barrier for anti-tissue adhesion. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. Frequency stability improvement for piezoresistive micromechanical oscillators via synchronization

    NASA Astrophysics Data System (ADS)

    Pu, Dong; Huan, Ronghua; Wei, Xueyong

    2017-03-01

    Synchronization phenomenon first discovered in Huygens' clock shows that the rhythms of oscillating objects can be adjusted via an interaction. Here we show that the frequency stability of a piezoresistive micromechanical oscillator can be enhanced via synchronization. The micromechanical clamped-clamped beam oscillator is built up using the electrostatic driving and piezoresistive sensing technique and the synchronization phenomenon is observed after coupling it to an external oscillator. An enhancement of frequency stability is obtained in the synchronization state. The influences of the synchronizing perturbation intensity and frequency detuning applied on the oscillator are studied experimentally. A theoretical analysis of phase noise leads to an analytical formula for predicting Allan deviation of the frequency output of the piezoresistive oscillator, which successfully explains the experimental observations and the mechanism of frequency stability enhancement via synchronization.

  3. Conflict, sticks and carrots: war increases prosocial punishments and rewards

    PubMed Central

    Gneezy, Ayelet; Fessler, Daniel M. T.

    2012-01-01

    Unlike most species, humans cooperate extensively with group members who are not closely related to them, a pattern sustained in part by punishing non-cooperators and rewarding cooperators. Because internally cooperative groups prevail over less cooperative rival groups, it is thought that violent intergroup conflict played a key role in the evolution of human cooperation. Consequently, it is plausible that propensities to punish and reward will be elevated during intergroup conflict. Using experiments conducted before, during and after the 2006 Israel–Hezbollah war, we show that, during wartime, people are more willing to pay costs to punish non-cooperative group members and reward cooperative group members. Rather than simply increasing within-group solidarity, violent intergroup conflict thus elicits behaviours that, writ large, enhance cooperation within the group, thereby making victory more likely. PMID:21653590

  4. The American Home Front: Revolutionary War, Civil War, World War I, World War II

    DTIC Science & Technology

    1983-01-01

    ledgm ents ................................................... xvii WAR AND SOCIETY IN AMERICA: SOME QUESTIONS ..... I 1. THE AMERICAN REVOLUTION 5 The...Price of War ...................................... 6 A Revolutionary Society at War ............................ 8 The Revolutionary Economy...obilizing the Union for War .................................... 67 Civil War and American Society . ................................ 71 O rganizing the

  5. Journey in Aeronautical Research: A Career at NASA Langley Research Center. No. 12; Monographs in Aerospace History

    NASA Technical Reports Server (NTRS)

    Phillips, W. Hewitt

    1998-01-01

    An autobiography, of a noted aeronautical engineer, W. Hewitt Phillips, whose career spanned 58 years (1940-1998) at NASA Langley is presented. This work covers his early years to the Sputnik launch. His interests have been in research in aeronautics and in the related problems of spaceflight. After an introduction, his early life through the college years is reviewed, and his early interest in model airplanes is described. The first assignment for the National Advisory Committee for Aeronautics (NACA), which would later become NASA, was with the Flight Research Division. His early work involved "Flying Qualities", i.e., the stability and control characteristics of an airplane. The next chapter describes his early analytical studies. His work during World War II in the design of military airplanes, and the other effects of the war on research activities, is covered in the next two chapters. This research was involved in such innovations and refinements as the swept wing, the flettner tabs, servo tabs, spring tabs and whirlerons. The rest of the work covers the research which Mr. Hewitt was involved in, after the war until the Sputnik launch. These areas include unsteady lift, measurements of turbulence in the atmosphere, gust alleviation, and lateral response to random turbulence. He was also involved in several investigations of airplane accidents. The last two chapters cover the administration of the Langley Research Center, and the dawn of the Space Age. A complete bibliography of reports written by Mr. Hewitt, is included.

  6. Nuclear deterrence in the Arab-Israeli conflict. A case study in Egyptian-Israeli relations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shikaki, K.I.

    1986-01-01

    In order to achieve security and stability, and maximize the chances for resolving the Arab-Israeli conflict, should Egypt and Israel adopt declared nuclear deterrence doctrines. Or would such a move be ineffective, dangerous, or even disastrous. The nuclearization of the Middle East is not necessary: military threats to the survival of the states in the region do not justify the introduction of nuclear weapons. Nuclearization is not desirable: deterrence theory's assumptions and implications exhibit intellectual weakness and its explanatory power is unsatisfactory; nuclear deterrence may reduce the frequency of war, but it pays little attention to the consequences of war;more » and in comparison to defense, nuclear deterrence may lack credibility. Presently, Israel has nuclear capability and delivery systems sufficient to provide security to its vital areas through deterrence of or defense against Arab attacks. The Arabs do not, however, believe that such security extends to the Arab territories occupied by Israel during the June 1967 war. To supply security, nuclear deterrence must be effective, stable, and credible. In a multinuclear environment, the Egyptians and Israelis are likely to meet the requirement for an effective deterrence: the possession of a nuclear capability sufficient to inflict an enormous amount of death and destruction. If the Arabs and Israelis sought and adopted strategies of deterrence, they might be able to meet the requirement for a stable deterrence: the acquisition of second strike capabilities.« less

  7. N-Allyl- N, N-Bis(trimethylsilyl)amine as a Novel Electrolyte Additive To Enhance the Interfacial Stability of a Ni-Rich Electrode for Lithium-Ion Batteries.

    PubMed

    Zheng, Qinfeng; Xing, Lidan; Yang, Xuerui; Li, Xiangfeng; Ye, Changchun; Wang, Kang; Huang, Qiming; Li, Weishan

    2018-05-16

    Enhancing the electrode/electrolyte interface stability of high-capacity LiNi 0.8 Co 0.15 Al 0.05 O 2 (LNCA) cathode material is urgently required for its application in next-generation lithium-ion battery. Herein, we demonstrate that enhanced interfacial stability of LNCA can be achieved by simply introducing 2 wt % N-allyl- N, N-bis(trimethylsilyl)amine (NNB) electrolyte additive. Electrolyte oxidation reactions and electrode structural destruction are greatly suppressed in the electrolyte with NNB additive, leading to improved cyclic stability of LNCA from 72.8 to 86.2% after 300 cycles. The mechanism of NNB on improving the cyclic stability of LNCA has been verified to its excellent solid electrolyte interface (SEI) film-forming capability. Moreover, the X-ray diffraction and X-ray photoelectron spectroscopy results indicate that the NNB-derived Si-containing SEI film restrains the Li/Ni disorder of LNCA during cycling, which further improves the cyclic stability of Ni-rich LNCA. Importantly, the charging/discharging test reveals that the NNB additive effectively improves the cyclic stability of the LNCA/graphite full cell.

  8. Examination of molecular mechanism for the enhanced thermal stability of anthocyanins by metal cations and polysaccharides.

    PubMed

    Tachibana, Noriko; Kimura, Yukihiro; Ohno, Takashi

    2014-01-15

    Anthocyanins exhibit colour variation over wide pH range but the colour stability is relatively low at the physiological pH. To improve the stability of anthocyanins in neutral to weakly acidic pH region, effects of metal cations and polysaccharides on the colour stability of cyanidin-3-glucoside (C3G) were examined by ultraviolet-visible and resonance Raman spectroscopies. C3G was thermally stabilized by the addition of Fe(3+) but formed aggregation. However, further addition of anionic polysaccharides enhanced the thermal stability of C3G without aggregation. Similar stabilisation was confirmed for delphinidin-3-glucoside (D3G) but not for pelargonidin-3-glucoside. The stability of anthocyanins considerably varied depending on pHs and kinds of metal cations, polysaccharides and buffer molecules. The characteristic resonance Raman bands of C3G-Fe(3+) and D3G-Fe(3+) complexes were significantly affected by the addition of alginate, (18)O/(16)O-isotope substitution, and Fe(2+)/Fe(3+)-replacement. These results suggest that alginate associates with C3G through Fe(3+) to form a stable complex, which enhances the thermal stability of C3G. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion

    NASA Astrophysics Data System (ADS)

    Zhao, Zhao; Fu, Jinglin; Dhakal, Soma; Johnson-Buck, Alexander; Liu, Minghui; Zhang, Ting; Woodbury, Neal W.; Liu, Yan; Walter, Nils G.; Yan, Hao

    2016-02-01

    Cells routinely compartmentalize enzymes for enhanced efficiency of their metabolic pathways. Here we report a general approach to construct DNA nanocaged enzymes for enhancing catalytic activity and stability. Nanocaged enzymes are realized by self-assembly into DNA nanocages with well-controlled stoichiometry and architecture that enabled a systematic study of the impact of both encapsulation and proximal polyanionic surfaces on a set of common metabolic enzymes. Activity assays at both bulk and single-molecule levels demonstrate increased substrate turnover numbers for DNA nanocage-encapsulated enzymes. Unexpectedly, we observe a significant inverse correlation between the size of a protein and its activity enhancement. This effect is consistent with a model wherein distal polyanionic surfaces of the nanocage enhance the stability of active enzyme conformations through the action of a strongly bound hydration layer. We further show that DNA nanocages protect encapsulated enzymes against proteases, demonstrating their practical utility in functional biomaterials and biotechnology.

  10. Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion

    PubMed Central

    Zhao, Zhao; Fu, Jinglin; Dhakal, Soma; Johnson-Buck, Alexander; Liu, Minghui; Zhang, Ting; Woodbury, Neal W.; Liu, Yan; Walter, Nils G.; Yan, Hao

    2016-01-01

    Cells routinely compartmentalize enzymes for enhanced efficiency of their metabolic pathways. Here we report a general approach to construct DNA nanocaged enzymes for enhancing catalytic activity and stability. Nanocaged enzymes are realized by self-assembly into DNA nanocages with well-controlled stoichiometry and architecture that enabled a systematic study of the impact of both encapsulation and proximal polyanionic surfaces on a set of common metabolic enzymes. Activity assays at both bulk and single-molecule levels demonstrate increased substrate turnover numbers for DNA nanocage-encapsulated enzymes. Unexpectedly, we observe a significant inverse correlation between the size of a protein and its activity enhancement. This effect is consistent with a model wherein distal polyanionic surfaces of the nanocage enhance the stability of active enzyme conformations through the action of a strongly bound hydration layer. We further show that DNA nanocages protect encapsulated enzymes against proteases, demonstrating their practical utility in functional biomaterials and biotechnology. PMID:26861509

  11. Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion.

    PubMed

    Zhao, Zhao; Fu, Jinglin; Dhakal, Soma; Johnson-Buck, Alexander; Liu, Minghui; Zhang, Ting; Woodbury, Neal W; Liu, Yan; Walter, Nils G; Yan, Hao

    2016-02-10

    Cells routinely compartmentalize enzymes for enhanced efficiency of their metabolic pathways. Here we report a general approach to construct DNA nanocaged enzymes for enhancing catalytic activity and stability. Nanocaged enzymes are realized by self-assembly into DNA nanocages with well-controlled stoichiometry and architecture that enabled a systematic study of the impact of both encapsulation and proximal polyanionic surfaces on a set of common metabolic enzymes. Activity assays at both bulk and single-molecule levels demonstrate increased substrate turnover numbers for DNA nanocage-encapsulated enzymes. Unexpectedly, we observe a significant inverse correlation between the size of a protein and its activity enhancement. This effect is consistent with a model wherein distal polyanionic surfaces of the nanocage enhance the stability of active enzyme conformations through the action of a strongly bound hydration layer. We further show that DNA nanocages protect encapsulated enzymes against proteases, demonstrating their practical utility in functional biomaterials and biotechnology.

  12. Enhanced stability of ZnO-based inverted organic photovoltaic devices by phosphonic acid modification

    NASA Astrophysics Data System (ADS)

    MacLeod, Bradley; Tremolet de Villers, Bertrand; Cowan, Sarah; Ratcliff, Erin; Olson, Dana

    2014-03-01

    Solution-processed ZnO thin films are now commonly used as n-type bottom contacts in inverted-geometry organic photovoltaics (OPVs). The use of ZnO eliminates the need for highly-reactive top-contact (air-interface) electrode material, such as calcium and aluminum which are commonly used in conventional geometries, which enables operational lifetimes of unencapsulated devices to shift from minutes or hours to days. Modification of the ZnO film by self-assembled monolayers (SAMs) has been shown to enhance performance as well as air-stability during storage. We modify ZnO with dipolar phosphonic acids and observe enhanced performance and stability. We show for the first time devices measured under continuous illumination at one-sun intensity which have significantly enhanced stability when utilizing SAM-modified ZnO. These continuous-illumination stability measurements allow us to investigate the degradation mechanisms of these more stable inverted OPV devices. This work was was supported by of the Center for Interface Science: Solar Electric Materials (CISSEM), an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Award Number DE-SC0001084.

  13. Enhanced Luminescent Stability through Particle Interactions in Silicon Nanocrystal Aggregates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, Joseph B.; Dandu, Naveen; Velizhanin, Kirill A.

    2015-10-27

    Close-packed assemblies of ligand-passivated colloidal nanocrystals can exhibit enhanced photoluminescent stability, but the origin of this effect is unclear. Here, we use experiment, simulation, and ab initio computation to examine the influence of interparticle interactions on the photoluminescent stability of silicon nanocrystal aggregates. The time-dependent photoluminescence emitted by structures ranging in size from a single quantum dot to agglomerates of more than a thousand is compared with Monte Carlo simulations of noninteracting ensembles using measured single-particle blinking data as input. In contrast to the behavior typically exhibited by the metal chalcogenides, the measured photoluminescent stability shows an enhancement with respectmore » to the noninteracting scenario with increasing aggregate size. We model this behavior using time-dependent density functional theory calculations of energy transfer between neighboring nanocrystals as a function of nanocrystal size, separation, and the presence of charge and/or surface-passivation defects. Our results suggest that rapid exciton transfer from “bright” nanocrystals to surface trap states in nearest-neighbors can efficiently fill such traps and enhance the stability of emission by promoting the radiative recombination of slowly diffusing excited electrons.« less

  14. Commercial aviation alternative fuels initiative

    DOT National Transportation Integrated Search

    2010-04-22

    This presentation looks at alternative fuels to enhance environmental stability, reduction of greenhouse gas emissions, air quality benefits (e.g., SOx and PM), fuel supply stability, and fuel price stability.

  15. Glass composition development for stabilization of lead based paints

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marra, J.C.

    1996-10-01

    Exposure to lead can lead to adverse health affects including permanent damage to the central nervous system. Common means of exposure to lead are from ingestion of lead paint chips or breathing of dust from deteriorating painted surfaces. The U.S. Army has over 101 million square feet of buildings dating to World War II or earlier. Many of these structures were built before the 1978 ban on lead based paints. The U.S. Army Corps of Engineers CERL is developing technologies to remove and stabilize lead containing organic coatings. Promising results have been achieved using a patented flame spray process thatmore » utilizes a glass frit to stabilize the hazardous constituents. When the glass frit is sprayed onto the paint containing substrate, differences in thermal expansion coefficients between the frit and the paint results in spalling of the paint from the substrate surface. The removed fragments are then collected and remelted to stabilize the hazardous constituents and allow for disposal as non-hazardous waste. Similar successful results using a patented process involving microwave technology for paint removal have also been achieved. In this process, the painted surface is coated with a microwave coupling compound that when exposed to microwave energy results in the spalling of the hazardous paint from the surface. The fragments can again be accumulated and remelted for stabilization and disposal.« less

  16. Highly thermostable fluorescent proteins

    DOEpatents

    Bradbury, Andrew M [Santa Fe, NM; Waldo, Geoffrey S [Santa Fe, NM; Kiss, Csaba [Los Alamos, NM

    2011-11-29

    Thermostable fluorescent proteins (TSFPs), methods for generating these and other stability-enhanced proteins, polynucleotides encoding such proteins, and assays and method for using the TSFPs and TSFP-encoding nucleic acid molecules are provided. The TSFPs of the invention show extremely enhanced levels of stability and thermotolerance. In one case, for example, a TSFP of the invention is so stable it can be heated to 99.degree. C. for short periods of time without denaturing, and retains 85% of its fluorescence when heated to 80.degree. C. for several minutes. The invention also provides a method for generating stability-enhanced variants of a protein, including but not limited to fluorescent proteins.

  17. Highly thermostable fluorescent proteins

    DOEpatents

    Bradbury, Andrew M [Santa Fe, NM; Waldo, Geoffrey S [Santa Fe, NM; Kiss, Csaba [Los Alamos, NM

    2011-03-22

    Thermostable fluorescent proteins (TSFPs), methods for generating these and other stability-enhanced proteins, polynucleotides encoding such proteins, and assays and method for using the TSFPs and TSFP-encoding nucleic acid molecules are provided. The TSFPs of the invention show extremely enhanced levels of stability and thermotolerance. In one case, for example, a TSFP of the invention is so stable it can be heated to 99.degree. C. for short periods of time without denaturing, and retains 85% of its fluorescence when heated to 80.degree. C. for several minutes. The invention also provides a method for generating stability-enhanced variants of a protein, including but not limited to fluorescent proteins.

  18. Highly thermostable fluorescent proteins

    DOEpatents

    Bradbury, Andrew M [Santa Fe, NM; Waldo, Geoffrey S [Santa Fe, NM; Kiss, Csaba [Los Alamos, NM

    2012-05-01

    Thermostable fluorescent proteins (TSFPs), methods for generating these and other stability-enhanced proteins, polynucleotides encoding such proteins, and assays and method for using the TSFPs and TSFP-encoding nucleic acid molecules are provided. The TSFPs of the invention show extremely enhanced levels of stability and thermotolerance. In one case, for example, a TSFP of the invention is so stable it can be heated to 99.degree. C. for short periods of time without denaturing, and retains 85% of its fluorescence when heated to 80.degree. C. for several minutes. The invention also provides a method for generating stability-enhanced variants of a protein, including but not limited to fluorescent proteins.

  19. National E-Learning Strategy to Enhance and Enrich the Iraqi Universities

    ERIC Educational Resources Information Center

    Elameer, Amer Saleem; Idrus, Rozhan M.

    2011-01-01

    Nowadays, the HE (higher education) sector of Iraq has suffered severe disruption and mass destruction due to the war and, in general, only 10% of its remaining operational sectors are in the acceptable conditions. This research is an attempt to plan a PS (proposed strategy) for the Iraqi HE sector that can be executed easily in Iraq as a part of…

  20. Learning Online during Active Duty and after Separation: Gulf War Veterans' Experience

    ERIC Educational Resources Information Center

    Garvey, Kim V.

    2017-01-01

    Higher education has a long-standing relationship with veterans. Under the auspices of federal funding such as the 1862 Morrill Land-Grant Act and the 1944 GI Bill, scores of veterans and active duty personnel have used their educational benefits to earn a college degree. In the 21st century, the 2009 enhancements to the post-9/11 GI Bill amounted…

  1. Globe Watch. Teachers' Guide for Globe Watch IV: Mexico, Canada, Finland, Japan, the Arms Race, the Iran-Iraq War.

    ERIC Educational Resources Information Center

    Turner, Ginny

    To enhance the use of the Globe Watch IV public television series, produced jointly by Hampden-Sydney College (Virginia) and the University of North Carolina Center for Public Television, each lesson in this guide provides: (1) a statement of the objective of the program; (2) a synopsis of the issue discussed; (3) background information; (4) brief…

  2. Stabilization of ultrathin (hydroxy)oxide films on transition metal substrates for electrochemical energy conversion

    DOE PAGES

    Zeng, Zhenhua; Chang, Kee-Chul; Kubal, Joseph; ...

    2017-05-08

    Design of cost-effective electrocatalysts with enhanced stability and activity is of paramount importance for the next generation of energy conversion systems, including fuel cells and electrolyzers. However, electrocatalytic materials generally improve one of these properties at the expense of the other. Here, using Density Functional Theory calculations and electrochemical surface science measurements, we explore atomic-level features of ultrathin (hydroxy)oxide films on transition metal substrates and demonstrate that these films exhibit both excellent stability and activity for electrocatalytic applications. The films adopt structures with stabilities that significantly exceed bulk Pourbaix limits, including stoichiometries not found in bulk and properties that aremore » tunable by controlling voltage, film composition, and substrate identity. Using nickel (hydroxy)oxide/Pt(111) as an example, we further show how the films enhance activity for hydrogen evolution through a bifunctional effect. Finally, the results suggest design principles for a new class of electrocatalysts with simultaneously enhanced stability and activity for energy conversion.« less

  3. Stabilization of ultrathin (hydroxy)oxide films on transition metal substrates for electrochemical energy conversion

    NASA Astrophysics Data System (ADS)

    Zeng, Zhenhua; Chang, Kee-Chul; Kubal, Joseph; Markovic, Nenad M.; Greeley, Jeffrey

    2017-06-01

    Design of cost-effective electrocatalysts with enhanced stability and activity is of paramount importance for the next generation of energy conversion systems, including fuel cells and electrolysers. However, electrocatalytic materials generally improve one of these properties at the expense of the other. Here, using density functional theory calculations and electrochemical surface science measurements, we explore atomic-level features of ultrathin (hydroxy)oxide films on transition metal substrates and demonstrate that these films exhibit both excellent stability and activity for electrocatalytic applications. The films adopt structures with stabilities that significantly exceed bulk Pourbaix limits, including stoichiometries not found in bulk and properties that are tunable by controlling voltage, film composition, and substrate identity. Using nickel (hydroxy)oxide/Pt(111) as an example, we further show how the films enhance activity for hydrogen evolution through a bifunctional effect. The results suggest design principles for this class of electrocatalysts with simultaneously enhanced stability and activity for energy conversion.

  4. Japan.

    PubMed

    1989-02-01

    Japan consists of 3900 islands and lies off the east coast of Asia. Even though Japan is one of the most densely populated nations in the world, its growth rate has stabilized at .5%. 94% of all children go to senior high school and almost 90% finish. Responsibility for the sick, aged, and infirmed is changing from the family and private sector to government. Japan was founded in 600 BC and its 1st capital was in Nara (710-1867). The Portuguese, the 1st Westerners to make contact with Japan in 1542, opened trade which lasted until the mid 17th century. US Navy Commodore Matthew Perry forced Japan to reopen in 1854. Following wars with China and Russia in the late 1800s and early 1900s respectively, Japan took part in World Wars I and II. In between these wars Japan invaded Manchuria and China. The US dropped an atomic bomb on Hiroshima and Nagasaki and the Japanese surrendered in September, 1945 ending World War II (WWII). Following, WWII, the Allied Powers guided Japan's establishment as a nonthreatening nation and a democratic parliamentary government (a constitutional monarchy) with a limited defense force. Japan remains one of the most politically stable of all postwar democracies. The Liberal Democratic Party's Noboru Takeshita became prime minister in 1987. Japan has limited natural resources and only 19% of the land is arable. Japanese ingenuity and skill combine to produce one of the highest per hectare crop yields in the world. Japan is a major economic power, and its and the US economies are becoming more interdependent. Its exports, making up only 13% of the gross national product, mainly go to Canada and the US. Many in the US are concerned, however, with the trade deficit with Japan and are seeking ways to make trade more equitable. Japan wishes to maintain good relations with its Asian neighbors and other nations. The US and Japan enjoy a strong, productive relationship.

  5. Microbial stability of worm castings and sugarcane filter mud compost blended with biochar

    USDA-ARS?s Scientific Manuscript database

    Organic amendments such as worm castings and filter mud compost can provide nutrient rich substrates for enhanced plant growth. Physico-chemical and microbial stability of these substrates might be enhanced with the addition of biochar. A series of experiments was carried out to determine the stab...

  6. Posttraumatic Growth and Dyadic Adjustment among War Veterans and their Wives

    PubMed Central

    Lahav, Yael; Kanat-Maymon, Yaniv; Solomon, Zahava

    2017-01-01

    The controversy regarding the nature of posttraumatic growth includes two main competing claims: one which argues that posttraumatic growth reflects authentic positive changes and the other which argues that posttraumatic growth reflects illusory defenses. While the former might suggest that posttraumatic growth enhances intimacy and close relationships, the latter might imply that posttraumatic growth hinders interpersonal relations. The present study aimed to test these claims by investigating the association between posttraumatic growth and dyadic adjustment over time at both the individual and dyadic levels, and the potential role of posttraumatic stress symptoms. Former prisoners of war and comparable war veterans and their wives (n = 229) were assessed twice, 30–31 (T1) and 35–38 (T2) years after the 1973 Yom Kippur War in Israel, with regard to posttraumatic growth, posttraumatic stress symptoms and dyadic adjustment. Results indicated that posttraumatic growth was associated with both elevated posttraumatic stress symptoms and low dyadic adjustment among both husbands and wives. Posttraumatic stress symptoms at T1 and T2 mediated the association between posttraumatic growth and dyadic adjustment. Wives' posttraumatic growth at T1 predicted posttraumatic growth and dyadic adjustment of the husbands at T2. The higher the wives' posttraumatic growth, the higher the posttraumatic growth and the lower the dyadic adjustment of the husbands in the subsequent measure. The findings suggest that posttraumatic growth reflects defensive beliefs which undermine marital relationships and that posttraumatic growth might be transmitted between spouses and implicated in the deterioration of the marital relationship over time. PMID:28713307

  7. A recurrent WARS mutation is a novel cause of autosomal dominant distal hereditary motor neuropathy.

    PubMed

    Tsai, Pei-Chien; Soong, Bing-Wen; Mademan, Inès; Huang, Yen-Hua; Liu, Chia-Rung; Hsiao, Cheng-Tsung; Wu, Hung-Ta; Liu, Tze-Tze; Liu, Yo-Tsen; Tseng, Yen-Ting; Lin, Kon-Ping; Yang, Ueng-Cheng; Chung, Ki Wha; Choi, Byung-Ok; Nicholson, Garth A; Kennerson, Marina L; Chan, Chih-Chiang; De Jonghe, Peter; Cheng, Tzu-Hao; Liao, Yi-Chu; Züchner, Stephan; Baets, Jonathan; Lee, Yi-Chung

    2017-05-01

    Distal hereditary motor neuropathy is a heterogeneous group of inherited neuropathies characterized by distal limb muscle weakness and atrophy. Although at least 15 genes have been implicated in distal hereditary motor neuropathy, the genetic causes remain elusive in many families. To identify an additional causal gene for distal hereditary motor neuropathy, we performed exome sequencing for two affected individuals and two unaffected members in a Taiwanese family with an autosomal dominant distal hereditary motor neuropathy in which mutations in common distal hereditary motor neuropathy-implicated genes had been excluded. The exome sequencing revealed a heterozygous mutation, c.770A > G (p.His257Arg), in the cytoplasmic tryptophanyl-tRNA synthetase (TrpRS) gene (WARS) that co-segregates with the neuropathy in the family. Further analyses of WARS in an additional 79 Taiwanese pedigrees with inherited neuropathies and 163 index cases from Australian, European, and Korean distal hereditary motor neuropathy families identified the same mutation in another Taiwanese distal hereditary motor neuropathy pedigree with different ancestries and one additional Belgian distal hereditary motor neuropathy family of Caucasian origin. Cell transfection studies demonstrated a dominant-negative effect of the p.His257Arg mutation on aminoacylation activity of TrpRS, which subsequently compromised protein synthesis and reduced cell viability. His257Arg TrpRS also inhibited neurite outgrowth and led to neurite degeneration in the neuronal cell lines and rat motor neurons. Further in vitro analyses showed that the WARS mutation could potentiate the angiostatic activities of TrpRS by enhancing its interaction with vascular endothelial-cadherin. Taken together, these findings establish WARS as a gene whose mutations may cause distal hereditary motor neuropathy and alter canonical and non-canonical functions of TrpRS. © The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  8. Damping Goes the Distance in Golf

    NASA Technical Reports Server (NTRS)

    2004-01-01

    In the late 1980s, Dr. Benjamin Dolgin of NASA s Jet Propulsion Laboratory developed a concept for a high-damping graphite/viscoelastic material for the Strategic Defense Initiative (popularly referred to as "Star Wars"), as part of a space-based laser anti-missile program called "Asterix." Dolgin drummed up this concept with the intention of stabilizing weapons launch platforms in space, where there is no solid ground to firmly support these structures. Without the inclusion of high-damping material, the orbital platforms were said to vibrate for 20 minutes after force was applied - a rate deemed "unacceptable" by leaders of the Strategic Defense Initiative.

  9. War experiences and psychotic symptoms among former child soldiers in Northern Uganda: the mediating role of post-war hardships – the WAYS Study

    PubMed Central

    Amone-P’Olak, Kennedy; Otim, Balaam Nyeko; Opio, George; Ovuga, Emilio; Meiser-Stedman, Richard

    2014-01-01

    Psychotic symptoms have been associated with post-traumatic stress disorder and war experiences. However, the relationships between types of war experiences, the onset and course of psychotic symptoms, and post-war hardships in child soldiers have not been investigated. This study assessed whether various types of war experiences contribute to psychotic symptoms differently and whether post-war hardships mediated the relationship between war experiences and later psychotic symptoms. In an ongoing longitudinal cohort study (the War-Affected Youths Survey), 539 (61% male) former child soldiers were assessed for psychotic symptoms, post-war hardships, and previous war experiences. Regression analyses were used to assess the contribution of different types of war experiences on psychotic symptoms and the mediating role of post-war hardships in the relations between previous war experiences and psychotic symptoms. The findings yielded ‘witnessing violence’, ‘deaths and bereavement’, ‘involvement in hostilities’, and ‘sexual abuse’ as types of war experiences that significantly and independently predict psychotic symptoms. Exposure to war experiences was related to psychotic symptoms through post-war hardships (β = .18, 95% confidence interval = [0.10, 0.25]) accounting for 50% of the variance in their relationship. The direct relation between previous war experiences and psychotic symptoms attenuated but remained significant (β = .18, 95% confidence interval = [0.12, 0.26]). Types of war experiences should be considered when evaluating risks for psychotic symptoms in the course of providing emergency humanitarian services in post-conflict settings. Interventions should consider post-war hardships as key determinants of psychotic symptoms among war-affected youths. PMID:24718435

  10. Does it matter how I perceive my nation? National symbols, national identification and attitudes toward immigrants.

    PubMed

    Finell, Eerika; Olakivi, Antero; Liebkind, Karmela; Lipsanen, Jari

    2013-12-01

    We examined how the ways of imagining one's own nation relate to the relationship between national identification and individuals' attitudes towards immigrants. National imagination is studied through two types of national symbols representing the nation in terms of confrontation between groups (i.e., war and sports) and a unique entity (i.e., nature and traditional culture). We found that national identification was positively associated with the degree to which individuals perceived their nation through a historical war and sports, which, in turn, enhanced negative attitudes toward immigrants. Unexpectedly, the degree to which individuals perceived their nation through nature and traditional culture was positively associated with positive intergroup attitudes. The results emphasize that the degree to which individuals perceive their nation through different national symbols is an important factor for understanding intergroup relations. © 2013 The Scandinavian Psychological Associations.

  11. Teacher-delivered resilience-focused intervention in schools with traumatized children following the second Lebanon War.

    PubMed

    Wolmer, Leo; Hamiel, Daniel; Barchas, Jack D; Slone, Michelle; Laor, Nathaniel

    2011-06-01

    The 2006 Lebanon War exposed children in the north of Israel to daily rocket attacks. To cope with the massive psychological needs, a teacher-delivered protocol focusing on enhancing personal resilience was implemented. Children were assessed for risk factors, symptoms, and adaptation before the 16-week program (Time 1; n = 983) and after its completion (Time 2; n = 563). At a 3-month follow-up (Time 3; n = 754) children were assessed together with a waiting-list comparison group (n = 1,152). Participating children showed a significant symptom decrease at Time 2 and significantly fewer symptoms than the control group at Time 3. Six or more risk factors were associated with greater symptoms and parental concern about the child's adaptive functioning. Teachers are valuable cost-effective providers for clinically informed interventions after mass trauma and disaster. Copyright © 2011 International Society for Traumatic Stress Studies.

  12. C-5 Propynyl Modifications Enhance the Mechanical Stability of DNA.

    PubMed

    Aschenbrenner, Daniela; Baumann, Fabian; Milles, Lukas F; Pippig, Diana A; Gaub, Hermann E

    2015-07-20

    Increased thermal or mechanical stability of DNA duplexes is desired for many applications in nanotechnology or -medicine where DNA is used as a programmable building block. Modifications of pyrimidine bases are known to enhance thermal stability and have the advantage of standard base-pairing and easy integration during chemical DNA synthesis. Through single-molecule force spectroscopy experiments with atomic force microscopy and the molecular force assay we investigated the effect of pyrimidines harboring C-5 propynyl modifications on the mechanical stability of double-stranded DNA. Utilizing these complementary techniques, we show that propynyl bases significantly increase the mechanical stability if the DNA is annealed at high temperature. In contrast, modified DNA complexes formed at room temperature and short incubation times display the same stability as non-modified DNA duplexes. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Improved image reconstruction of low-resolution multichannel phase contrast angiography

    PubMed Central

    P. Krishnan, Akshara; Joy, Ajin; Paul, Joseph Suresh

    2016-01-01

    Abstract. In low-resolution phase contrast magnetic resonance angiography, the maximum intensity projected channel images will be blurred with consequent loss of vascular details. The channel images are enhanced using a stabilized deblurring filter, applied to each channel prior to combining the individual channel images. The stabilized deblurring is obtained by the addition of a nonlocal regularization term to the reverse heat equation, referred to as nonlocally stabilized reverse diffusion filter. Unlike reverse diffusion filter, which is highly unstable and blows up noise, nonlocal stabilization enhances intensity projected parallel images uniformly. Application to multichannel vessel enhancement is illustrated using both volunteer data and simulated multichannel angiograms. Robustness of the filter applied to volunteer datasets is shown using statistically validated improvement in flow quantification. Improved performance in terms of preserving vascular structures and phased array reconstruction in both simulated and real data is demonstrated using structureness measure and contrast ratio. PMID:26835501

  14. Stability and thermophysical studies on deep eutectic solvent based carbon nanotube nanofluid

    NASA Astrophysics Data System (ADS)

    Chen, Yan Yao; Walvekar, Rashmi; Khalid, Mohammad; Shahbaz, Kaveh; Gupta, T. C. S. M.

    2017-07-01

    Commercial coolants such as water, ethylene glycol and triethylene glycol possess very low thermal conductivity, high vapor pressure, corrosion issues and low thermal stability thus limiting the thermal enhancement of the nanofluids. Thus, a new type of base fluid known as deep eutectic solvents (DESs) is proposed in this work as a potential substitute for the conventional base fluid due to their unique solvent properties such as low vapor pressure, high thermal stability, biodegradability and non-flammability. In this work, 33 different DESs derived from phosphonium halide salt and ammonium halide salts were synthesised. Carbon nantubes (CNTs) with different concentrations (0.01 wt%-0.08 wt%) were dispersed into DESs with the help of sonication. Stability of the nanofluids were determined using both qualitative (visual observation) and quantitative (UV spectroscopy) approach. In addition, thermo-physical properties such as thermal conductivity, specific heat, viscosity and density were investigated. The stability results indicated that phosphonium based DESs have higher stability (up to 4 d) as compared to ammonium-based DESs (up to 3 d). Thermal enhancement of 30% was observed for ammonium based DES-CNT nanofluid whereas negative thermal enhancement was observed in phosphonium based DES-CNT nanofluid.

  15. Enhancing Economic Stability Utilizing the High Technologies in Community Colleges: A Case Study.

    ERIC Educational Resources Information Center

    Mehnert, Barbara H.; Kurki, Allan W.

    Strategies to enhance the economic stability of community colleges through high technology approaches are discussed in this paper. First, general economic problems facing higher education are identified, and the ways in which they influence community colleges are described. Next, 10 strategies to aid in the economic recovery of community colleges…

  16. Predicting domestic and community violence by soldiers living in a conflict region.

    PubMed

    Nandi, Corina; Elbert, Thomas; Bambonye, Manassé; Weierstall, Roland; Reichert, Manfred; Zeller, Anja; Crombach, Anselm

    2017-11-01

    Past research revealed war trauma and posttraumatic stress disorder (PTSD) symptoms as potential predictors for domestic and community violence in crisis regions and among soldiers in different armed conflicts. The impact of family violence and other adversities experienced in childhood as well as of a combat-enhanced appeal for aggressive behavior (appetitive aggression) remains to be specified. In the present study, the authors separately predicted violence against children, intimate partner violence and community violence in 381 Burundian soldiers returning from foreign deployment and living in a post- conflict region. Using path analysis, they aimed to disentangle the independent contributions and pathways of the following variables: Exposure to war trauma and childhood familial violence, PTSD and depression symptom severity, and appetitive aggression. Childhood familial violence had an independent effect on all contexts of violence and was the only significant predictor for violence against the soldiers' own children. Intimate partner violence was additionally predicted by depression symptom severity, while community violence was additionally predicted by PTSD symptom severity and appetitive aggression. Besides war-related mental ill-health and appetitive aggression, violent experiences during childhood development must not be overlooked as a factor fueling the cycle of violence in conflict regions. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  17. An assessment of survey measures used across key epidemiologic studies of United States Gulf War I Era Veterans

    PubMed Central

    2013-01-01

    Over the past two decades, 12 large epidemiologic studies and 2 registries have focused on U.S. veterans of the 1990–1991 Gulf War Era. We conducted a review of these studies’ research tools to identify existing gaps and overlaps of efforts to date, and to advance development of the next generation of Gulf War Era survey tools. Overall, we found that many of the studies used similar instruments. Questions regarding exposures were more similar across studies than other domains, while neurocognitive and psychological tools were the most variable. Many studies focused on self-reported survey results, with a range of validation practices. However, physical exams, biomedical assessments, and specimen storage were not common. This review suggests that while research may be able to pool data from past surveys, future surveys need to consider how their design can yield data comparable with previous surveys. Additionally, data that incorporate recent technologies in specimen and genetic analyses would greatly enhance such survey data. When combined with existing data on deployment-related exposures and post-deployment health conditions, longitudinal follow-up of existing studies within this collaborative framework could represent an important step toward improving the health of veterans. PMID:23302181

  18. Effectiveness of psychosocial intervention enhancing resilience among war-affected children and the moderating role of family factors.

    PubMed

    Diab, Marwan; Peltonen, Kirsi; Qouta, Samir R; Palosaari, Esa; Punamäki, Raija-Leena

    2015-02-01

    The study examines, first, the effectiveness of a psychosocial intervention based on Teaching Recovery Techniques (TRT) to increase resiliency among Palestinian children, exposed to a major trauma of war. Second, it analyses the role of family factors (maternal attachment and family atmosphere) as moderating the intervention impacts on resilience. School classes in Gaza were randomized into intervention (N=242) and control (N=240) groups. The percentage of girls (49.4%) and boys (50.6%) were equal, and the child age was 10-13 years in both groups. Children reported positive indicators of their mental health (prosocial behaviour and psychosocial well-being) at baseline (T1), post-intervention (T2) and at a six-month follow-up (T3). At T1 they accounted their exposure to war trauma. Mothers reported about their willingness to serve as an attachment figure, and the child reported about the family atmosphere. Resilience was conceptualized as a presence of positive indications of mental health despite trauma exposure. Against our hypothesis, the intervention did not increase the level of resilience statistically significantly, nor was the effect of the intervention moderated by maternal attachment responses or family atmosphere. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Assessing the Impact of Electrostatic Drag on Processive Molecular Motor Transport.

    PubMed

    Smith, J Darby; McKinley, Scott A

    2018-06-04

    The bidirectional movement of intracellular cargo is usually described as a tug-of-war among opposite-directed families of molecular motors. While tug-of-war models have enjoyed some success, recent evidence suggests underlying motor interactions are more complex than previously understood. For example, these tug-of-war models fail to predict the counterintuitive phenomenon that inhibiting one family of motors can decrease the functionality of opposite-directed transport. In this paper, we use a stochastic differential equations modeling framework to explore one proposed physical mechanism, called microtubule tethering, that could play a role in this "co-dependence" among antagonistic motors. This hypothesis includes the possibility of a trade-off: weakly bound trailing molecular motors can serve as tethers for cargoes and processing motors, thereby enhancing motor-cargo run lengths along microtubules; however, this introduces a cost of processing at a lower mean velocity. By computing the small- and large-time mean-squared displacement of our theoretical model and comparing our results to experimental observations of dynein and its "helper protein" dynactin, we find some supporting evidence for microtubule tethering interactions. We extrapolate these findings to predict how dynein-dynactin might interact with the opposite-directed kinesin motors and introduce a criterion for when the trade-off is beneficial in simple systems.

  20. A room temperature strategy towards enhanced performance and bias stability of oxide thin film transistor with a sandwich structure channel layer

    NASA Astrophysics Data System (ADS)

    Zeng, Yong; Ning, Honglong; Zheng, Zeke; Zhang, Hongke; Fang, Zhiqiang; Yao, Rihui; Xu, Miao; Wang, Lei; Lan, Linfeng; Peng, Junbiao; Lu, Xubing

    2017-04-01

    Thermal annealing is a conventional and effective way to improve the bias stress stability of oxide thin film transistors (TFT) on solid substrates. However, it is still a challenge for enhancing the bias stress stability of oxide TFTs on flexible substrates by high-temperature post-treatment due to the thermal sensitivity of flexible substrates. Here, a room temperature strategy is presented towards enhanced performance and bias stability of oxide TFTs by intentionally engineering a sandwich structure channel layer consisting of a superlattice with aluminum doped zinc oxide (AZO) and Al2O3 thin films. The Al2O3/AZO/Al2O3-TFTs not only exhibit a saturation mobility of 9.27 cm2 V-1 s-1 and a linear mobility of 11.38 cm2 V-1 s-1 but also demonstrate a better bias stress stability than AZO/Al2O3-TFT. Moreover, the underlying mechanism of this enhanced electrical performance of TFTs with a sandwich structure channel layer is that the bottom Al2O3 thin films can obviously improve the crystalline phase of AZO films while decreasing electrical trapping centers and adsorption sites for undesirable molecules such as water and oxygen.

  1. Synthesis of urease hybrid nanoflowers and their enhanced catalytic properties.

    PubMed

    Somturk, Burcu; Yilmaz, Ismail; Altinkaynak, Cevahir; Karatepe, Aslıhan; Özdemir, Nalan; Ocsoy, Ismail

    2016-05-01

    Increasing numbers of materials have been extensively used as platforms for enzyme immobilization to enhance catalytic activity and stability. Although stability of enzyme was accomplished with immobilization approaches, activity of the most of the enzymes was declined after immobilization. Herein, we synthesize the flower shaped-hybrid nanomaterials called hybrid nanoflower (HNF) consisting of urease enzyme and copper ions (Cu(2+)) and report a mechanistic elucidation of enhancement in both activity and stability of the HNF. We demonstrated how experimental factors influence morphology of the HNF. We proved that the HNF (synthesized from 0.02mgmL(-1) urease in 10mM PBS (pH 7.4) at +4°C) exhibited the highest catalytic activity of ∼2000% and ∼4000% when stored at +4°C and RT, respectively compared to free urease. The highest stability was also achieved by this HNF by maintaining 96.3% and 90.28% of its initial activity within storage of 30 days at +4°C and RT, respectively. This dramatically enhanced activity is attributed to high surface area, nanoscale-entrapped urease and favorable urease conformation of the HNF. The exceptional catalytic activity and stability properties of HNF can be taken advantage of to use it in fields of biomedicine and chemistry. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Bio-Inspired Innovation and National Security

    DTIC Science & Technology

    2010-01-01

    legal and illegal, to enhance athlete performance. While legality is not a critical issue for combat soldiers, safety is. Current strength...Operating critical infrastructure? How do we operate when the families of our Servicepeople are exposed to the same threat? Clearly, we are unprepared to...against their will because of the belief that Iraq would use weapons of mass destruction against American forces. After the war, it was discovered that

  3. Enhancing Human Resource Capability in the Tanzania Peoples Defense Force (TPDF)

    DTIC Science & Technology

    2006-06-01

    Tanzania’s elephants , thus making the Selous a big attraction to tourists (Pan- African News Agency, 1999). The problem of poaching is not only confined...the Cold War and the collapse of the Soviet Union changed the strategic environment. Refugees from conflict torn areas, poaching , small arms...changed the strategic environment. Refugees from conflict torn areas, poaching , small arms proliferation, political and religious fundamentalism, drug

  4. From Sputnik to Minerva: Education and American National Security (Defense Horizons, Number 65, January 2009

    DTIC Science & Technology

    2009-01-01

    training (along with a living stipend), loan guarantees for homes, farms, and businesses, and unemployment pay for returning Servicemembers...16 million World War II veterans had participated in education and training programs. A sizeable percentage of the American population benefited...provided for U.S. training on a grant basis to students from abroad to enhance civil-military relationships and provide professional military

  5. A Single Superpower in a Quasi-Unipolar Political System: Who Defines the Role of the United States?

    ERIC Educational Resources Information Center

    De Villier, Paul Wayne

    For U.S. neo-idealists, the 1990s represented a moment to be seized, a time in which the strategies of conflict and confrontation of the Cold War period could be replaced by strategies designed to enhance cooperation among the nation-states. In 2001, the George W. Bush administration found itself in the position of continuing the same Bill Clinton…

  6. Dirty snow after nuclear war

    NASA Technical Reports Server (NTRS)

    Warren, S. G.; Wiscombe, W. J.

    1985-01-01

    It is shown that smoke from fires started by nuclear explosions could continue to cause significant disruption even after it has fallen from the atmosphere, by lowering the reflectivity of snow and sea ice surfaces, with possible effects on climate in northern latitudes caused by enhanced absorption of sunlight. The reduced reflectivity could persist for several years on Arctic sea ice and on the ablation area of the Greenland ice sheet.

  7. Enhancing U.S. National Security: The Case for Hemispheric Free Trade

    DTIC Science & Technology

    1992-04-15

    to shape much of the post-World War II international order. Institutions created then at U.S. behest, and which still guide the world’s affairs today... the United Nations, the World Bank, the International Monetary Fund, the General Agreement on Tariffs and Trade, the Organization of American...those services or agricultural products effectively. Given this erosion in international trade discipline, the GATT has understandably come under

  8. Management Sciences Division Annual Report (10th)

    DTIC Science & Technology

    1993-01-01

    of the Weapon System Management Information System (WSMIS). TheI Aircraft Sustainability Model ( ASM ) is the computational technique employed by...provisioning. We enhanced the capabilities of RBIRD by using the Aircraft Sustainability Model ( ASM ) for the spares calculation. ASM offers many... ASM for several years to 3 compute spares for war. It is also fully compatible with the Air Force’s peacetime spares computation system (D041). This

  9. Refugees and Evacuees: Enhancing Historical Understanding through Irish Historical Fiction with Key Stage 2 and Early Key Stage 3 Pupils

    ERIC Educational Resources Information Center

    Bracey, Paul; Gove-Humphries, Alison; Jackson, Darius

    2006-01-01

    This article explores the use of historical fiction as a means of undertaking a historical enquiry into the experiences of refugees and evacuees with Key Stage 2 and 3 pupils. The authors reflect on the reasons why people have come to Britain before focussing on specific circumstances associated with World War 2. This is undertaken through the use…

  10. Maintaining Space Superiority

    DTIC Science & Technology

    2014-02-01

    object that may present a threat to his or h er satellites must still provide direction that responds to that threat This article discusses a dilemma...space-based threats .ŕ The Air Force achieves space superiority by conducting operations that support the war fighter (space force enhancement); by...the space era, threats and issues have arisen to chal- lenge US operations in these areas. Indeed, as declared in the National Security Space Strategy

  11. Enhancing U.S. Counterterrorism Efforts: The Role of State and Local Actors

    DTIC Science & Technology

    2013-04-01

    for LAPD ; A Panel Created by the Mayor Says Local Efforts in the War on Terror Would Benefit from Placing Officers with Foreign Departments ,” Los ...it is far more likely that cities may undertake smaller regional variations on the theme.”47 Indeed, other police forces from Los Angeles , Chicago...24 CHAPTER 4: THE NEW YORK CITY POLICE DEPARTMENT (NYPD): .................28 A BOTTOM-UP APPROACH

  12. Coming home from prison: Adapting military resilience training to enhance successful community reintegration for justice-involved Iraq-Afghanistan veterans.

    PubMed

    Sreenivasan, Shoba; Rosenthal, Joel; Smee, Daniel E; Wilson, Keith; McGuire, Jim

    2018-05-01

    We propose a veteran-centric justice model of resilience training developed by the military for assisting service members coming home from war and modify it to assist Iraq/Afghanistan veterans coming home from prison. Incarceration has been identified as a stress aftereffect of the prolonged Iraq and Afghanistan combat deployments. Notably, the rate of Iraq and Afghanistan-era incarcerated veterans increased from 4% to 13% between 2004 and 2012 for all incarcerated veterans. Successful reentry to the community from prison incarceration is difficult, with rearrest and reincarceration a frequent occurrence. Moreover, combat stress conditions may weaken the justice-involved Iraq/Afghanistan's veteran's ability to face challenges posed by the return home from prison. As in the war zone, the return home from prison may be idealized with unrealistic expectations and/or goals, thus setting up the returning veteran for disappointment, anger, deepening of alienation and disconnection from larger civilian society, and the risk of return to maladaptive mechanisms for coping. Resilience training can be provided in psychoeducational venues prior to prison release and with follow-up postrelease. Resilience building offers promise as an intervention to enhance the justice-involved veteran's successful community reentry. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  13. Confined Rayleigh-Bénard, Rotating Rayleigh-Bénard, and Double Diffusive Convection: A Unifying View on Turbulent Transport Enhancement through Coherent Structure Manipulation

    NASA Astrophysics Data System (ADS)

    Chong, Kai Leong; Yang, Yantao; Huang, Shi-Di; Zhong, Jin-Qiang; Stevens, Richard J. A. M.; Verzicco, Roberto; Lohse, Detlef; Xia, Ke-Qing

    2017-08-01

    Many natural and engineering systems are simultaneously subjected to a driving force and a stabilizing force. The interplay between the two forces, especially for highly nonlinear systems such as fluid flow, often results in surprising features. Here we reveal such features in three different types of Rayleigh-Bénard (RB) convection, i.e., buoyancy-driven flow with the fluid density being affected by a scalar field. In the three cases different stabilizing forces are considered, namely (i) horizontal confinement, (ii) rotation around a vertical axis, and (iii) a second stabilizing scalar field. Despite the very different nature of the stabilizing forces and the corresponding equations of motion, at moderate strength we counterintuitively but consistently observe an enhancement in the flux, even though the flow motion is weaker than the original RB flow. The flux enhancement occurs in an intermediate regime in which the stabilizing force is strong enough to alter the flow structures in the bulk to a more organized morphology, yet not too strong to severely suppress the flow motions. Near the optimal transport enhancements all three systems exhibit a transition from a state in which the thermal boundary layer (BL) is nested inside the momentum BL to the one with the thermal BL being thicker than the momentum BL. The observed optimal transport enhancement is explained through an optimal coupling between the suction of hot or fresh fluid and the corresponding scalar fluctuations.

  14. The "War Poets": Evolution of a Literary Conscience in World War I.

    ERIC Educational Resources Information Center

    Galambos, Ellen

    1983-01-01

    Pre-World War I poetry often used picturesque images which blinded people to the actual horrors of war. The war poets, who experienced the destruction of World War I, led the way in expressing new images of the devastation and death of war, rather than focusing on honor and glory. (IS)

  15. The lifelong struggle of Finnish World War II veterans.

    PubMed

    Nivala, Sirkka; Sarvimäki, Anneli

    2015-01-01

    In many countries veterans from World War II are growing old. Research has shown that war experiences continue to impact those who have been involved in war for a long time. The present study targets old injured war veterans from World War II in Finland. The aim of this study was to produce knowledge of the impact of war experiences and injuries on the lifespan of Finnish war veterans. The method used was grounded theory. Data were collected by interviewing 20 aged war veterans in their homes. The analysis resulted in four categories, with also subcategories: (1) lost childhood and youth; (2) war traumas impacting life; (3) starting life from scratch; and (4) finding one's own place. A substantive theory of war veterans' lifelong struggle for freedom throughout the lifespan was outlined. The war overshadowed the whole lifespan of the veterans, but in old age they finally felt free. Since war experiences vary depending on historical context, a formal theory would require additional research.

  16. Long-term outcomes of war-related death of family members in Kosovar civilian war survivors.

    PubMed

    Morina, Nexhmedin; Reschke, Konrad; Hofmann, Stefan G

    2011-04-01

    Exposure to war-related experiences can comprise a broad variety of experiences and the very nature of certain war-related events has generally been neglected. To examine the long-term outcomes of war-related death of family members, the authors investigated the prevalence rates of major depressive episode (MDE), anxiety disorders, and quality of life among civilian war survivors with or without war-related death of first-degree family members 9 years after the war in Kosovo. Compared to participants without war-related death of family members, those who had experienced such loss had signficantly higher prevalence rates of MDE, posttraumatic stress disorder, and generalized anxiety disorder, and reported a lower quality of life 9 years after the war. These results indicate that bereaved civilian survivors of war experience significant mental health problems many years after the war.

  17. Enhanced enzyme kinetic stability by increasing rigidity within the active site.

    PubMed

    Xie, Yuan; An, Jiao; Yang, Guangyu; Wu, Geng; Zhang, Yong; Cui, Li; Feng, Yan

    2014-03-14

    Enzyme stability is an important issue for protein engineers. Understanding how rigidity in the active site affects protein kinetic stability will provide new insight into enzyme stabilization. In this study, we demonstrated enhanced kinetic stability of Candida antarctica lipase B (CalB) by mutating the structurally flexible residues within the active site. Six residues within 10 Å of the catalytic Ser(105) residue with a high B factor were selected for iterative saturation mutagenesis. After screening 2200 colonies, we obtained the D223G/L278M mutant, which exhibited a 13-fold increase in half-life at 48 °C and a 12 °C higher T50(15), the temperature at which enzyme activity is reduced to 50% after a 15-min heat treatment. Further characterization showed that global unfolding resistance against both thermal and chemical denaturation also improved. Analysis of the crystal structures of wild-type CalB and the D223G/L278M mutant revealed that the latter formed an extra main chain hydrogen bond network with seven structurally coupled residues within the flexible α10 helix that are primarily involved in forming the active site. Further investigation of the relative B factor profile and molecular dynamics simulation confirmed that the enhanced rigidity decreased fluctuation of the active site residues at high temperature. These results indicate that enhancing the rigidity of the flexible segment within the active site may provide an efficient method for improving enzyme kinetic stability.

  18. Lipid cross-linking of nanolipoprotein particles substantially enhances serum stability and cellular uptake [Lipid crosslinking enhances the stability of nanolipoprotein particles in serum by multiple orders of magnitude

    DOE PAGES

    Gilmore, Sean F.; Blanchette, Craig D.; Scharadin, Tiffany M.; ...

    2016-07-13

    Nanolipoprotein particles (NLPs) consist of a discoidal phospholipid lipid bilayer confined by an apolipoprotein belt. NLPs are a promising platform for a variety of biomedical applications due to their biocompatibility, size, definable composition, and amphipathic characteristics. However, poor serum stability hampers the use of NLPs for in vivo applications such as drug formulation. In this study, NLP stability was enhanced upon the incorporation and subsequent UV-mediated intermolecular cross-linking of photoactive DiynePC phospholipids in the lipid bilayer, forming cross-linked nanoparticles (X-NLPs). Both the concentration of DiynePC in the bilayer and UV exposure time significantly affected the resulting X-NLP stability in 100%more » serum, as assessed by size exclusion chromatography (SEC) of fluorescently labeled particles. Cross-linking did not significantly impact the size of X-NLPs as determined by dynamic light scattering and SEC. X-NLPs had essentially no degradation over 48 h in 100% serum, which is a drastic improvement compared to non-cross-linked NLPs (50% degradation by ~10 min). X-NLPs had greater uptake into the human ATCC 5637 bladder cancer cell line compared to non-cross-linked particles, indicating their potential utility for targeted drug delivery. X-NLPs also exhibited enhanced stability following intravenous administration in mice. Lastly, these results collectively support the potential utility of X-NLPs for a variety of in vivo applications.« less

  19. Lipid cross-linking of nanolipoprotein particles substantially enhances serum stability and cellular uptake [Lipid crosslinking enhances the stability of nanolipoprotein particles in serum by multiple orders of magnitude

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gilmore, Sean F.; Blanchette, Craig D.; Scharadin, Tiffany M.

    Nanolipoprotein particles (NLPs) consist of a discoidal phospholipid lipid bilayer confined by an apolipoprotein belt. NLPs are a promising platform for a variety of biomedical applications due to their biocompatibility, size, definable composition, and amphipathic characteristics. However, poor serum stability hampers the use of NLPs for in vivo applications such as drug formulation. In this study, NLP stability was enhanced upon the incorporation and subsequent UV-mediated intermolecular cross-linking of photoactive DiynePC phospholipids in the lipid bilayer, forming cross-linked nanoparticles (X-NLPs). Both the concentration of DiynePC in the bilayer and UV exposure time significantly affected the resulting X-NLP stability in 100%more » serum, as assessed by size exclusion chromatography (SEC) of fluorescently labeled particles. Cross-linking did not significantly impact the size of X-NLPs as determined by dynamic light scattering and SEC. X-NLPs had essentially no degradation over 48 h in 100% serum, which is a drastic improvement compared to non-cross-linked NLPs (50% degradation by ~10 min). X-NLPs had greater uptake into the human ATCC 5637 bladder cancer cell line compared to non-cross-linked particles, indicating their potential utility for targeted drug delivery. X-NLPs also exhibited enhanced stability following intravenous administration in mice. Lastly, these results collectively support the potential utility of X-NLPs for a variety of in vivo applications.« less

  20. Public Health Crisis: the Need for Primary Prevention in Failed and Fragile States.

    PubMed

    Quinn, John; Stoeva, Preslava; Zelený, Tomáš; Nanda, Toozy; Tomanová, Alžběta; Bencko, Vladimír

    2017-09-01

    A new 'normal' in global affairs may be erupting from large global powers to that of non-state actors and proxies committing violence through scaled conflict in a post-Westphalian world generating significant global health policy challenges. Health security of populations are multifactorial and indirectly proportional to war, conflict and disaster. Preventing conflict and avoiding the health vacuum that occurs in war and violence may be best practices for policy makers. This paper considers an approach of applying clinical primary prevention principles to global health policy. Brief policy review of current standards and practices in health security in fragile and failed states and prevention; and definitions discussion. A short case study series are presented with best practices, with risk and outcome review. The global balance of power and order may be shifting through geopolitical transference and inadequate action by major global power brokers. Health security in at risk nation-states may be decreasing as a result. Small scale conflict with large-scale violence threatens health security and may experience increased incidence and prevalence in fragile and failed states. Preventative policy to resuscitate fragile and failed states and prevent further external and internal shocks may support health and promote a positive feedback loop of further state stability and increased health security. Public health policy shift to mitigate state failure and public health crisis in war and conflict through the basis of primary prevention may provide best practices and maximize health security for at risk populations. Copyright© by the National Institute of Public Health, Prague 2017

  1. Corporate interests, philanthropies, and the peace movement.

    PubMed

    Wright, T; Rodriguez, F; Waitzkin, H

    1986-01-01

    Corporate and philanthropic involvement in the peace movement is growing. In considering medical peace groups as examples, we have studied the ways that corporate and philanthropic funding have shaped the course of activism. Our methods have included: review of the Foundations Grant Index from 1974-1983; analysis of corporations' and foundations' criteria for grants in the categories of peace, arms control, and disarmament; interviews with leaders of activist organizations and with foundation officials; and our own experiences in the peace movement. Corporate interests in preventing nuclear war stem from a concern for global stability in which world markets may expand, and from a hope to frame issues posed by the peace movement in a way that will not challenge basic structures of power and finance. Several general features make peace groups respectable and attractive to philanthropies; an uncritical stance toward corporate participation in the arms race; a viewpoint that the main danger of nuclear war stems from a profound, bilateral conflict between the United States and the Soviet Union; and a single-issue focus that does not deal with the many related problems reflecting the injustices of capitalism. The two major medical groups working for peace, Physicians for Social Responsibility (PSR) and International Physicians for the Prevention of Nuclear War (IPPNW), have accomplished many goals; however, their adherence to subtle criteria of respectability and their dependence on philanthropic funding have limited the scope of their activism. The struggle for peace can not succeed without fundamental changes in the corporate system that initiates, maintains, and promotes the arms race.

  2. War Finance: Economic and Historic Lessons

    ERIC Educational Resources Information Center

    Boldt, David J.; Kassis, Mary Mathewes

    2004-01-01

    In this article, the authors provide a historical review of how the U.S. government has funded its participation in major wars during the past 150 years. They focus attention on five conflicts--the Civil War, World War I, World War II, the Korean War and the Vietnam War. Those conflicts were funded in different ways, with each funding method…

  3. Enhancing Activity and Stability of Uricase from Lactobacillus plantarum by Zeolite immobilization

    NASA Astrophysics Data System (ADS)

    Iswantini, D.; Nurhidayat, N.; Sarah

    2017-03-01

    Lactobacillus plantarum has been known be able to produce uricase for uric acid biosensor. Durability and stability of L. plantarum in generating uricase enzyme was low. Hence, we tried to enhance its durability and stability by immobilizing it onto activated 250 mg zeolite at room temperature using 100 μL L.plantarum suspension and 2.87 mM uric acid, while Michaelis-Menten constant (KM) and Vmax were obtained at 6.7431 mM and 0.9171 µA consecutively, and the linearity range was 0.1-3.3 mM (R2 = 0.9667). Limit of detection (LOD) and limit of quantification (LOQ) value of the measurement were 0.4827 mM and 1.6092 mM respectively. Biosensor stability treatment was carried out in two different treatments, using the same electrode and using disposable electrode. The disposable electrode stability showed better result based on repeated measurements, but stability was still need improvement.

  4. Biopolyester-based systems containing naturally occurring compounds with enhanced thermo-oxidative stability.

    PubMed

    Arrigo, Rossella; Morici, Elisabetta; Dintcheva, Nadka Tzankova

    2016-11-02

    This work presents a sustainable approach for the stabilization of polylactic acid (PLA) against thermo-oxidative aging. Naturally occurring phenolic and polyphenolic compounds, such as ferulic acid (FerAc), vanillic acid (VanAc), quercetin (Querc) and vitamin E (VitE), were introduced into PLA. The preliminary characterization of the systems formulated containing different amounts of natural stabilizers showed that all compounds used acted as plasticizers, leading to a decrease in rheological functions with respect to neat PLA, without significantly modifying the crystallinity of the raw material. The study of the thermo-oxidative behavior of neat PLA and PLA/natural compound systems, performed by spectrometric and thermal analyses, indicated that all stabilizers considered were able to exert a remarkable antioxidant action against thermo-oxidative phenomena. All natural compounds considered are thus proposed as ecofriendly stabilizers, to get fully bio-based polymer systems with enhanced thermo-oxidative stability, suitable for biomedical applications.

  5. Enhanced superconductivity of fullerenes

    DOEpatents

    Washington, II, Aaron L.; Teprovich, Joseph A.; Zidan, Ragaiy

    2017-06-20

    Methods for enhancing characteristics of superconductive fullerenes and devices incorporating the fullerenes are disclosed. Enhancements can include increase in the critical transition temperature at a constant magnetic field; the existence of a superconducting hysteresis over a changing magnetic field; a decrease in the stabilizing magnetic field required for the onset of superconductivity; and/or an increase in the stability of superconductivity over a large magnetic field. The enhancements can be brought about by transmitting electromagnetic radiation to the superconductive fullerene such that the electromagnetic radiation impinges on the fullerene with an energy that is greater than the band gap of the fullerene.

  6. 36 CFR 1229.12 - What are the requirements during a state of war or threatened war?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... during a state of war or threatened war? 1229.12 Section 1229.12 Parks, Forests, and Public Property... § 1229.12 What are the requirements during a state of war or threatened war? (a) Destruction of records... war between the United States and any other nation or when hostile action appears imminent, the head...

  7. 77 FR 43117 - Meeting of the Cold War Advisory Committee for the Cold War Theme Study

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... the Cold War Advisory Committee for the Cold War Theme Study AGENCY: National Park Service, Interior... Committee Act, 5 U.S.C. Appendix, that the Cold War Advisory Committee for the Cold War Theme Study will... National Park Service (NPS) concerning the Cold War Theme Study. DATES: The teleconference meeting will be...

  8. Enhanced structural stability and photo responsiveness of CH 3NH 3SnI 3 perovskite via pressure-induced amorphization and recrystallization

    DOE PAGES

    Lu, Xujie; Wang, Yonggang; Stoumpos, Constantinos C.; ...

    2016-10-01

    An organic–inorganic halide CH 3NH 3SnI 3 perovskite with significantly improved structural stability is obtained via pressure-induced amorphization and recrystallization. In situ high-pressure resistance measurements reveal an increased electrical conductivity by 300% in the pressure-treated perovskite. Photocurrent measurements also reveal a substantial enhancement in visible-light responsiveness. In conclusion, the mechanism underlying the enhanced properties is shown to be associated with the pressure-induced structural modification.

  9. Enhanced stability of monomer fold correlates with extreme drug resistance of HIV-1 protease.

    PubMed

    Louis, John M; Tözsér, József; Roche, Julien; Matúz, Krisztina; Aniana, Annie; Sayer, Jane M

    2013-10-29

    During treatment, mutations in HIV-1 protease (PR) are selected rapidly that confer resistance by decreasing affinity to clinical protease inhibitors (PIs). As these unique drug resistance mutations can compromise the fitness of the virus to replicate, mutations that restore conformational stability and activity while retaining drug resistance are selected on further evolution. Here we identify several compensating mechanisms by which an extreme drug-resistant mutant bearing 20 mutations (PR20) with >5-fold increased Kd and >4000-fold decreased affinity to the PI darunavir functions. (1) PR20 cleaves, albeit poorly, Gag polyprotein substrates essential for viral maturation. (2) PR20 dimer, which exhibits distinctly enhanced thermal stability, has highly attenuated autoproteolysis, thus likely prolonging its lifetime in vivo. (3) The enhanced stability of PR20 results from stabilization of the monomer fold. Both monomeric PR20(T26A) and dimeric PR20 exhibit Tm values 6-7.5 °C higher than those for their PR counterparts. Two specific mutations in PR20, L33F and L63P at sites of autoproteolysis, increase the Tm of monomeric PR(T26A) by ~8 °C, similar to PR20(T26A). However, without other compensatory mutations as seen in PR20, L33F and L63P substitutions, together, neither restrict autoproteolysis nor significantly reduce binding affinity to darunavir. To determine whether dimer stability contributes to binding affinity for inhibitors, we examined single-chain dimers of PR and PR(D25N) in which the corresponding identical monomer units were covalently linked by GGSSG sequence. Linking of the subunits did not appreciably change the ΔTm on inhibitor binding; thus stabilization by tethering appears to have little direct effect on enhancing inhibitor affinity.

  10. Effects of dual tasks and dual-task training on postural stability: a systematic review and meta-analysis

    PubMed Central

    Ghai, Shashank; Ghai, Ishan; Effenberg, Alfred O

    2017-01-01

    The use of dual-task training paradigm to enhance postural stability in patients with balance impairments is an emerging area of interest. The differential effects of dual tasks and dual-task training on postural stability still remain unclear. A systematic review and meta-analysis were conducted to analyze the effects of dual task and training application on static and dynamic postural stability among various population groups. Systematic identification of published literature was performed adhering to Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines, from inception until June 2016, on the online databases Scopus, PEDro, MEDLINE, EMBASE, and SportDiscus. Experimental studies analyzing the effects of dual task and dual-task training on postural stability were extracted, critically appraised using PEDro scale, and then summarized according to modified PEDro level of evidence. Of 1,284 records, 42 studies involving 1,480 participants met the review’s inclusion criteria. Of the studies evaluating the effects of dual-task training on postural stability, 87.5% of the studies reported significant enhancements, whereas 30% of the studies evaluating acute effects of dual tasks on posture reported significant enhancements, 50% reported significant decrements, and 20% reported no effects. Meta-analysis of the pooled studies revealed moderate but significant enhancements of dual-task training in elderly participants (95% CI: 1.16–2.10) and in patients suffering from chronic stroke (−0.22 to 0.86). The adverse effects of complexity of dual tasks on postural stability were also revealed among patients with multiple sclerosis (−0.74 to 0.05). The review also discusses the significance of verbalization in a dual-task setting for increasing cognitive–motor interference. Clinical implications are discussed with respect to practical applications in rehabilitation settings. PMID:28356727

  11. Effects of dual tasks and dual-task training on postural stability: a systematic review and meta-analysis.

    PubMed

    Ghai, Shashank; Ghai, Ishan; Effenberg, Alfred O

    2017-01-01

    The use of dual-task training paradigm to enhance postural stability in patients with balance impairments is an emerging area of interest. The differential effects of dual tasks and dual-task training on postural stability still remain unclear. A systematic review and meta-analysis were conducted to analyze the effects of dual task and training application on static and dynamic postural stability among various population groups. Systematic identification of published literature was performed adhering to Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines, from inception until June 2016, on the online databases Scopus, PEDro, MEDLINE, EMBASE, and SportDiscus. Experimental studies analyzing the effects of dual task and dual-task training on postural stability were extracted, critically appraised using PEDro scale, and then summarized according to modified PEDro level of evidence. Of 1,284 records, 42 studies involving 1,480 participants met the review's inclusion criteria. Of the studies evaluating the effects of dual-task training on postural stability, 87.5% of the studies reported significant enhancements, whereas 30% of the studies evaluating acute effects of dual tasks on posture reported significant enhancements, 50% reported significant decrements, and 20% reported no effects. Meta-analysis of the pooled studies revealed moderate but significant enhancements of dual-task training in elderly participants (95% CI: 1.16-2.10) and in patients suffering from chronic stroke (-0.22 to 0.86). The adverse effects of complexity of dual tasks on postural stability were also revealed among patients with multiple sclerosis (-0.74 to 0.05). The review also discusses the significance of verbalization in a dual-task setting for increasing cognitive-motor interference. Clinical implications are discussed with respect to practical applications in rehabilitation settings.

  12. Relevance of Linear Stability Results to Enhanced Oil Recovery

    NASA Astrophysics Data System (ADS)

    Ding, Xueru; Daripa, Prabir

    2012-11-01

    How relevant can the results based on linear stability theory for any problem for that matter be to full scale simulation results? Put it differently, is the optimal design of a system based on linear stability results is optimal or even near optimal for the complex nonlinear system with certain objectives of interest in mind? We will address these issues in the context of enhanced oil recovery by chemical flooding. This will be based on an ongoing work. Supported by Qatar National Research Fund (a member of the Qatar Foundation).

  13. Inhomogeneous degradation in metal halide perovskites

    NASA Astrophysics Data System (ADS)

    Yang, Rong; Zhang, Li; Cao, Yu; Miao, Yanfeng; Ke, You; Wei, Yingqiang; Guo, Qiang; Wang, Ying; Rong, Zhaohua; Wang, Nana; Li, Renzhi; Wang, Jianpu; Huang, Wei; Gao, Feng

    2017-08-01

    Although the rapid development of organic-inorganic metal halide perovskite solar cells has led to certified power conversion efficiencies of above 20%, their poor stability remains a major challenge, preventing their practical commercialization. In this paper, we investigate the intrinsic origin of the poor stability in perovskite solar cells by using a confocal fluorescence microscope. We find that the degradation of perovskite films starts from grain boundaries and gradually extend to the center of the grains. Firmly based on our findings, we further demonstrate that the device stability can be significantly enhanced by increasing the grain size of perovskite crystals. Our results have important implications to further enhance the stability of optoelectronic devices based on metal halide perovskites.

  14. Enhancement of Peroxidase Stability Against Oxidative Self-Inactivation by Co-immobilization with a Redox-Active Protein in Mesoporous Silicon and Silica Microparticles

    NASA Astrophysics Data System (ADS)

    Sahare, P.; Ayala, M.; Vazquez-Duhalt, R.; Pal, U.; Loni, A.; Canham, L. T.; Osorio, I.; Agarwal, V.

    2016-09-01

    The study of the stability enhancement of a peroxidase immobilized onto mesoporous silicon/silica microparticles is presented. Peroxidases tend to get inactivated in the presence of hydrogen peroxide, their essential co-substrate, following an auto-inactivation mechanism. In order to minimize this inactivation, a second protein was co-immobilized to act as an electron acceptor and thus increase the stability against self-oxidation of peroxidase. Two heme proteins were immobilized into the microparticles: a fungal commercial peroxidase and cytochrome c from equine heart. Two types of biocatalysts were prepared: one with only covalently immobilized peroxidase (one-protein system) and another based on covalent co-immobilization of peroxidase and cytochrome c (two-protein system), both immobilized by using carbodiimide chemistry. The amount of immobilized protein was estimated spectrophotometrically, and the characterization of the biocatalyst support matrix was performed using Brunauer-Emmett-Teller (BET), scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDX), and Fourier transform infrared (FTIR) analyses. Stability studies show that co-immobilization with the two-protein system enhances the oxidative stability of peroxidase almost four times with respect to the one-protein system. Thermal stability analysis shows that the immobilization of peroxidase in derivatized porous silicon microparticles does not protect the protein from thermal denaturation, whereas biogenic silica microparticles confer significant thermal stabilization.

  15. How Much War Should Be Included in a Course on World War II?

    ERIC Educational Resources Information Center

    Schilling, Donald G.

    1993-01-01

    Contends that end of Cold War increases need for students to understand causes and aftermath of World War II. Recommends spending less time on military aspects of the war and more time on the economic, social, and cultural impact of total war. Provides a selected list of resources to be used in a college level course on the war. (CFR)

  16. Alternative materials for the modification and stabilization of unstable subgrade soils

    DOT National Transportation Integrated Search

    1997-05-01

    This study examines two lime by-products and two fly ashes for treatment of unstable (CBR<6) subgrade soils. The treatment methods include both modification and stabilization. Modification is temporily enhancing subgrade stability to improve construc...

  17. Biodiversity simultaneously enhances the production and stability of community biomass, but the effects are independent.

    PubMed

    Cardinale, Bradley J; Gross, Kevin; Fritschie, Keith; Flombaum, Pedro; Fox, Jeremy W; Rixen, Christian; van Ruijven, Jasper; Reich, Peter B; Scherer-Lorenzen, Michael; Wilsey, Brian J

    2013-08-01

    To predict the ecological consequences of biodiversity loss, researchers have spent much time and effort quantifying how biological variation affects the magnitude and stability of ecological processes that underlie the functioning of ecosystems. Here we add to this work by looking at how biodiversity jointly impacts two aspects of ecosystem functioning at once: (1) the production of biomass at any single point in time (biomass/area or biomass/ volume), and (2) the stability of biomass production through time (the CV of changes in total community biomass through time). While it is often assumed that biodiversity simultaneously enhances both of these aspects of ecosystem functioning, the joint distribution of data describing how species richness regulates productivity and stability has yet to be quantified. Furthermore, analyses have yet to examine how diversity effects on production covary with diversity effects on stability. To overcome these two gaps, we reanalyzed the data from 34 experiments that have manipulated the richness of terrestrial plants or aquatic algae and measured how this aspect of biodiversity affects community biomass at multiple time points. Our reanalysis confirms that biodiversity does indeed simultaneously enhance both the production and stability of biomass in experimental systems, and this is broadly true for terrestrial and aquatic primary producers. However, the strength of diversity effects on biomass production is independent of diversity effects on temporal stability. The independence of effect sizes leads to two important conclusions. First, while it may be generally true that biodiversity enhances both productivity and stability, it is also true that the highest levels of productivity in a diverse community are not associated with the highest levels of stability. Thus, on average, diversity does not maximize the various aspects of ecosystem functioning we might wish to achieve in conservation and management. Second, knowing how biodiversity affects productivity gives no information about how diversity affects stability (or vice versa). Therefore, to predict the ecological changes that occur in ecosystems after extinction, we will need to develop separate mechanistic models for each independent aspect of ecosystem functioning.

  18. The association between attachment and mental health symptoms among school-going adolescents in northern Uganda: the moderating role of war-related trauma.

    PubMed

    Okello, James; Nakimuli-Mpungu, Etheldreda; Musisi, Seggane; Broekaert, Eric; Derluyn, Ilse

    2014-01-01

    The association between attachment and mental health symptoms in adolescents in a post-conflict low resource setting has not been documented. We investigated the relationship between parent and peer attachment and posttraumatic stress, depression and anxiety symptoms in a sample of 551 adolescents aged 13-21 years old. Attachment quality was assessed using the Inventory of Parent and Peer Attachment (IPPA). Post-traumatic stress, depression and anxiety symptoms were assessed using the Impact of Events Scale Revised (IESR) and Hopkins Symptom Checklist for Adolescents (HSCL-37A) respectively. Gender differences in attachment relationships were determined using independent t-tests. Multivariate logistic regression was used to assess whether attachment relationships were independently associated with posttraumatic stress, depression and anxiety symptoms. Hierarchical linear regression analyses were conducted to explore the moderating role of war-related trauma. Our analyses revealed gender differences in attachment to parents, with males reporting stronger attachment than females. Parental attachment was protective against depression and anxiety symptoms but not posttraumatic stress symptoms after adjusting for potential confounders. Alienation by parents was independently associated with an increase in these mental health symptoms while peer attachment was not associated with any of these symptoms. However, in situations of severe trauma, our analyses showed that peer attachment was significantly protective against post-traumatic stress symptoms. Secure parental attachment is associated with better psychosocial adjustment in adolescents affected by war. Further, adolescents with secure peer attachment relationships in situations of severe war trauma may be less likely to develop posttraumatic stress symptoms. Interventions to enhance peer support in this post conflict setting would benefit this vulnerable population.

  19. The psychological impact of forced displacement and related risk factors on Eastern Congolese adolescents affected by war.

    PubMed

    Mels, Cindy; Derluyn, Ilse; Broekaert, Eric; Rosseel, Yves

    2010-10-01

    While the current knowledge base on the mental health effects of displacement is mainly limited to refugees residing in industrialised countries, this paper examines the impact of war-induced displacement and related risk factors on the mental health of Eastern Congolese adolescents, and compares currently internally displaced adolescents to returnees and non-displaced peers. Data were collected from a community sample of 819 adolescents aged 13 to 21 years, attending one of 10 selected schools across the Ituri district in the Democratic Republic of Congo. Respondents completed culturally adapted self-report measures of posttraumatic stress symptoms (using the Impact of Event Scale - Revised) and internalising and externalising behaviour problems (by means of the Hopkins Symptoms Checklist - 37 for Adolescents). Associated factors studied were age, sex, parental death, exposure to war-related violence and daily stressors. Internally displaced persons (IDPs) reported highest mean scores for the IES-R and the HSCL-37A internalising scale, followed by returnees, while non-displaced adolescents scored significantly lower. However, ANCOVA tests showed that posttraumatic stress and internalising symptoms were mainly associated with traumatic exposure and daily stressors and not with displacement status. Externalising problem scores were associated with traumatic exposure, daily stressors and displacement. Remarkably, death of father was associated with fewer externalising problems. Sex was differently associated with internalising and externalising problems through traumatic and daily stressors. As IDPs are highly exposed to violence and daily stressors, they report most psychological distress, when compared to returnees and non-displaced peers. The distinct mental health outcomes for returned youngsters illustrate how enhancing current socio-economic living conditions of war-affected adolescents could stimulate resilient outcomes, despite former trauma or displacement.

  20. The Association between Attachment and Mental Health Symptoms among School-Going Adolescents in Northern Uganda: The Moderating Role of War-Related Trauma

    PubMed Central

    Okello, James; Nakimuli-Mpungu, Etheldreda; Musisi, Seggane; Broekaert, Eric; Derluyn, Ilse

    2014-01-01

    Background The association between attachment and mental health symptoms in adolescents in a post-conflict low resource setting has not been documented. Methods We investigated the relationship between parent and peer attachment and posttraumatic stress, depression and anxiety symptoms in a sample of 551 adolescents aged 13–21 years old. Attachment quality was assessed using the Inventory of Parent and Peer Attachment (IPPA). Post-traumatic stress, depression and anxiety symptoms were assessed using the Impact of Events Scale Revised (IESR) and Hopkins Symptom Checklist for Adolescents (HSCL-37A) respectively. Gender differences in attachment relationships were determined using independent t-tests. Multivariate logistic regression was used to assess whether attachment relationships were independently associated with posttraumatic stress, depression and anxiety symptoms. Hierarchical linear regression analyses were conducted to explore the moderating role of war-related trauma. Results Our analyses revealed gender differences in attachment to parents, with males reporting stronger attachment than females. Parental attachment was protective against depression and anxiety symptoms but not posttraumatic stress symptoms after adjusting for potential confounders. Alienation by parents was independently associated with an increase in these mental health symptoms while peer attachment was not associated with any of these symptoms. However, in situations of severe trauma, our analyses showed that peer attachment was significantly protective against post-traumatic stress symptoms. Conclusions Secure parental attachment is associated with better psychosocial adjustment in adolescents affected by war. Further, adolescents with secure peer attachment relationships in situations of severe war trauma may be less likely to develop posttraumatic stress symptoms. Interventions to enhance peer support in this post conflict setting would benefit this vulnerable population. PMID:24614005

  1. Climatic Consequences of Nuclear Conflict

    NASA Astrophysics Data System (ADS)

    Robock, A.

    2011-12-01

    A nuclear war between Russia and the United States could still produce nuclear winter, even using the reduced arsenals of about 4000 total nuclear weapons that will result by 2017 in response to the New START treaty. A nuclear war between India and Pakistan, with each country using 50 Hiroshima-sized atom bombs as airbursts on urban areas, could produce climate change unprecedented in recorded human history. This scenario, using much less than 1% of the explosive power of the current global nuclear arsenal, would produce so much smoke from the resulting fires that it would plunge the planet to temperatures colder than those of the Little Ice Age of the 16th to 19th centuries, shortening the growing season around the world and threatening the global food supply. Crop model studies of agriculture in the U.S. and China show massive crop losses, even for this regional nuclear war scenario. Furthermore, there would be massive ozone depletion with enhanced ultraviolet radiation reaching the surface. These surprising conclusions are the result of recent research (see URL) by a team of scientists including those who produced the pioneering work on nuclear winter in the 1980s, using the NASA GISS ModelE and NCAR WACCM GCMs. The soot is self-lofted into the stratosphere, and the effects of regional and global nuclear war would last for more than a decade, much longer than previously thought. Nuclear proliferation continues, with nine nuclear states now, and more working to develop or acquire nuclear weapons. The continued environmental threat of the use of even a small number of nuclear weapons must be considered in nuclear policy deliberations in Russia, the U.S., and the rest of the world.

  2. The evolution of communities in the international oil trade network

    NASA Astrophysics Data System (ADS)

    Zhong, Weiqiong; An, Haizhong; Gao, Xiangyun; Sun, Xiaoqi

    2014-11-01

    International oil trade is a subset of global trade and there exist oil trade communities. These communities evolve over time and provide clues of international oil trade patterns. A better understanding of the international oil trade patterns is necessary for governments in policy making. To study the evolution of trade communities in the international oil trade network, we set up unweighted and weighted oil trade network models based on complex network theory using data from 2002 to 2011. We detected the communities in the oil trade networks and analyzed their evolutionary properties and stabilities over time. We found that the unweighted and weighted international oil trade networks show many different features in terms of community number, community scale, distribution of countries, quality of partitions, and stability of communities. Two turning points occurred in the evolution of community stability in the international oil trade network. One is the year 2004-2005 which correlates with changes in demand and supply in the world oil market after the Iraq War, and the other is the year 2008-2009 which is connected to the 2008 financial crisis. Different causations of instability show different features and this should be considered by policy makers.

  3. Is crisis stability still achievable?

    NASA Astrophysics Data System (ADS)

    Pollack, Joshua

    During the Cold War, the idea of crisis stability concerned whether the United States and the Soviet Union would be faced with powerful incentives to strike each other first with their nuclear weapons during periods of tension. This idea influenced the design of nuclear forces and guided aspects of nuclear arms control. The United States and Russia continue to operate large, alert nuclear forces, but at least three new factors have emerged that add significantly greater complexity to this picture. The first new factor consists of the development and deployment of new strategic military technologies that are entangled with nuclear weapons. These include strategic ballistic missile defenses, counter-space weapons, and strategic conventional weapons. The second new factor consists of new dyads of interacting strategic forces beyond US-Russia. These include US-China, US-North Korea, India-Pakistan, and India-China. The third new factor consists of the emergence of three-actor crisis stability dynamics, where the third actor is not necessarily nuclear-armed. This paper illustrates the concept with the US-North Korea-South Korea triangle. It briefly discusses the implications of these developments and reflects on the broad policy options that may be available.

  4. Next Generation Catalyst Engineering via Support Modification

    DTIC Science & Technology

    2016-01-21

    the effect of specific N functionalities on the stability of PtRu. DFT calculations show that N-defects such as pyrrolic and pyridinic N enhance the...stability of Pt in PtRu and that pyrrolic N improves the stability of PtRu by stabilizing both Pt and Ru. Hence, a balance between pyrrolic and

  5. Full-frame video stabilization with motion inpainting.

    PubMed

    Matsushita, Yasuyuki; Ofek, Eyal; Ge, Weina; Tang, Xiaoou; Shum, Heung-Yeung

    2006-07-01

    Video stabilization is an important video enhancement technology which aims at removing annoying shaky motion from videos. We propose a practical and robust approach of video stabilization that produces full-frame stabilized videos with good visual quality. While most previous methods end up with producing smaller size stabilized videos, our completion method can produce full-frame videos by naturally filling in missing image parts by locally aligning image data of neighboring frames. To achieve this, motion inpainting is proposed to enforce spatial and temporal consistency of the completion in both static and dynamic image areas. In addition, image quality in the stabilized video is enhanced with a new practical deblurring algorithm. Instead of estimating point spread functions, our method transfers and interpolates sharper image pixels of neighboring frames to increase the sharpness of the frame. The proposed video completion and deblurring methods enabled us to develop a complete video stabilizer which can naturally keep the original image quality in the stabilized videos. The effectiveness of our method is confirmed by extensive experiments over a wide variety of videos.

  6. The Evolution of Joint Operations during the Civil War

    DTIC Science & Technology

    2009-06-12

    requested a large quantity of anti-personnel mines to enhance the minefield in front of the land face.64 Lamb‘s requests did not elicit a significant... mines the Confederates had buried. Several of the men realized what they were (buried anti-personnel torpedoes) and systematically disabled them by...devices which today would include booby traps, land mines , naval mines and others. 118 Traverse--A fortified gun emplacement in a fortified position

  7. Finland, Sweden, and NATO: From Virtual to Formal Allies?

    DTIC Science & Technology

    2011-02-01

    NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION...rapid waning of the Cold War ideological conflict and growing attractiveness of Euro- pean integration eroded Finnish and Swedish motiva - tions for...membership? What would be NATO’s equities? These are important questions as NATO considers how best to implement the enhanced dialogue and

  8. State of the Science Review: Advances in Pain Management in Wounded Service Members over a Decade at War

    DTIC Science & Technology

    2014-01-01

    are subject to the development of tolerance and dependence and have a high abuse potential . For example, the average duration of hospitalization of...tions33,34 with the potential added benefits of mood elevation, sleep pattern normalization, and muscle relaxation. However, pain management with...vice members while reducing the development of tolerance with the potential added benefits of mood enhancement. Targeting Glia to Attenuate Morphine

  9. Army Sustainment. Volume 42, Issue 1, January-February 2010

    DTIC Science & Technology

    2010-02-01

    JANUARY–FEBRUARY 2010 5 n 2008, Faiza Elmasry noted on Voice of America that for more than 40 years after World War II, the United States and the...August Army Logistician Commentary: Logisticians Are Sustainers, Not Targeters MAJ Donald A. MacCuish 18 Contracting Agility in LOGCAP-Kuwait COL Scott...Service to the Field MG James E. Chambers 5 Army Strategic Management System: Enhancing Logistics Readiness David Lewis, Charles Glover , and Rob Frye 34

  10. Medical Effects of a Transuranic "Dirty Bomb".

    PubMed

    Durakovic, Asaf

    2017-03-01

    The modern military battlefields are characterized by the use of nonconventional weapons such as encountered in the conflicts of the Gulf War I and Gulf War II. Recent warfare in Iraq, Afghanistan, and the Balkans has introduced radioactive weapons to the modern war zone scenarios. This presents the military medicine with a new area of radioactive warfare with the potential large scale contamination of military and civilian targets with the variety of radioactive isotopes further enhanced by the clandestine use of radioactive materials in the terrorist radioactive warfare. Radioactive dispersal devices (RDDs), including the "dirty bomb," involve the use of organotropic radioisotopes such as iodine 131, cesium 137, strontium 90, and transuranic elements. Some of the current studies of RDDs involve large-scale medical effects, social and economic disruption of the society, logistics of casualty management, cleanup, and transportation preparedness, still insufficiently addressed by the environmental and mass casualty medicine. The consequences of a dirty bomb, particularly in the terrorist use in urban areas, are a subject of international studies of multiple agencies involved in the management of disaster medicine. The long-term somatic and genetic impact of some from among over 400 radioisotopes released in the nuclear fission include somatic and transgenerational genetic effects with the potential challenges of the genomic stability of the biosphere. The global contamination is additionally heightened by the presence of transuranic elements in the modern warzone, including depleted uranium recently found to contain plutonium 239, possibly the most dangerous substance known to man with one pound of plutonium capable of causing 8 billion cancers. The planning for the consequences of radioactive dirty bomb are being currently studied in reference to the alkaline earths, osteotropic, and stem cell hazards of internally deposited radioactive isotopes, in particular uranium and transuranic elements. The spread of radioactive materials in the area of the impact would expose both military and civilian personnel to the blast and dust with both inhalational, somatic, and gastrointestinal exposure, in the aftermath of the deployment of RDDs. The quantities of radioactive materials have proliferated from the original quantity of plutonium first isolated in 1941 from 0.5 mg to the current tens of thousands of kilograms in the strategic nuclear arsenal with the obvious potential consequences to the biosphere and mankind. In an event of RDD employment, the immediate goal of disaster and mass casualty medicine would be a synchronized effort to contain the scope of the event, followed by cleanup and treatment procedures. A pragmatic approach to this problem is not always possible because of unpredictability of the terrorist-use scenarios. Reprint & Copyright © 2017 Association of Military Surgeons of the U.S.

  11. The effect of nanoparticle aggregation on surfactant foam stability.

    PubMed

    AlYousef, Zuhair A; Almobarky, Mohammed A; Schechter, David S

    2018-02-01

    The combination of nanoparticles (NPs) and surfactant may offer a novel technique of generating stronger foams for gas mobility control. This study evaluates the potential of silica NPs to enhance the foam stability of three nonionic surfactants. Results showed that the concentration of surfactant and NPs is a crucial parameter for foam stability and that there is certain concentrations for strong foam generation. A balance in concentration between the nonionic surfactants and the NPs can enhance the foam stability as a result of forming flocs in solutions. At fixed surfactant concentration, the addition of NPs at low to intermediate concentrations can produce a more stable foam compared to the surfactant. The production of small population of flocs as a result of mixing the surfactant and NPs can enhance the foam stability by providing a barrier between the gas bubbles and delaying the coalescence of bubbles. Moreover, these flocs can increase the solution viscosity and, therefore, slow the drainage rate of thin aqueous film (lamellae). The measurements of foam half-life, bubble size, and mobility tests confirmed this conclusion. However, the addition of more solid particles or surfactant might have a negative impact on foam stability and reduce the maximum capillary pressure of coalescence as a result of forming extensive aggregates. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Novel formulations enhance the thermal stability of live-attenuated flavivirus vaccines

    PubMed Central

    Wiggan, O’Neil; Silengo, Shawn J.; Kinney, Richard M.; Osorio, Jorge E.; Huang, Claire Y.-H.; Stinchcomb, Dan T.

    2011-01-01

    Thermal stability is important for the manufacture, distribution and administration of vaccines, especially in tropical developing countries, where particularly adverse field conditions exist. Current live-attenuated flavivirus vaccines exhibit relatively poor liquid stability in clinical settings, and clinicians are instructed to discard the yellow fever vaccine 1h after reconstitution. We have identified novel combinations of excipients that greatly enhance the thermal stability of live-attenuated DEN-2 PDK-53-based flavivirus vaccine candidates. Liquid formulations comprising a sugar, albumin and a pluronic polymer minimized the loss of flavivirus infectious titer to less than 0.5log(10)pfu after storage for at least 8h at 37°C, 7 days at room temperature or at least 11 weeks at 4°C. Additionally, these formulations prevented reduction of viral infectivity after two freeze-thaw cycles of virus. Formulated candidate vaccines were readily lyophilized and reconstituted with minimal loss of viral titers. In mice, the formulations were safe and did not hinder the ability of the vaccine virus to generate a potent, protective immune response. These formulations provided significantly greater liquid-phase stability than has been reported previously for other flavivirus vaccine formulations. The enhanced thermal stability provided by the formulations described here will facilitate the effective distribution of flavivirus vaccines worldwide. PMID:21803103

  13. Understanding mail survey response rates among male reserve component Gulf War era veterans.

    PubMed

    Schumm, W R; Bollman, S R; Jurich, A P; Castelo, C; Sanders, D; Webb, F J

    2000-12-01

    In this study of current and former male Reserve and National Guard members from the State of Ohio, it was expected that veterans who were older, had more years of military service, who had participated in the Persian Gulf War, who were Euro-Americans, who were higher in rank, who had higher residential stability in Ohio, who belonged to the Air Force, who had higher formal education, and who belonged to the National Guard would have a greater investment in U.S. society as defined by 11 demographic variables. It was assumed that those with greater investment in society would more often have valid addresses and would be more likely to respond to a survey on military issues, thereby biasing sample outcomes in those directions. Results for male veterans were consistent with the hypothesis that investment in the society system would predict validity of addresses and response rates. In other words, results supported the idea that those veterans who might be expected to have a greater investment in U.S. society were more likely to be located and to respond (once located) to a survey concerning Desert Storm-era military service and its aftermath. Implications for future Desert Storm research are discussed.

  14. Treatment of war injuries of the shoulder with external fixators.

    PubMed

    Davila, Slavko; Mikulić, Danko; Davila, Neda Jarza; Popović, Ljiljana; Zupancić, Bozidar

    2005-05-01

    In this retrospective study, 18 patients with war injuries of the shoulder were reviewed to evaluate the technical problems associated with external fixation and to analyze the incidence of infection and late functional results. The average patient age was 28.5 years. All patients were male. Thirteen patients had explosive wounds, whereas five wounds were caused by gunshot missiles. All injuries were extensive in terms of bone and soft tissue defects. Six patients presented with complex injuries involving neurovascular structures. Sixteen patients were treated with external fixation. Application of the proximal pins of the external fixator through the humeral head was possible in eight patients, the scapula served as the site of proximal fixation in four patients, only the clavicle was available for placement of pins in two patients, and both the scapula and the clavicle had to be pinned to achieve proximal stabilization in two patients. In two patients, fixation was not possible and early amputation was performed. Infection was eventually eradicated in all patients, allowing for adequate soft tissue coverage of the wounds. Analysis of functional results at an average of 6 years after the injury showed a considerable degree of functional deficit in most patients.

  15. Enhancing Security and Stability in Afghanistan

    DTIC Science & Technology

    2015-12-01

    developing Afghan institutional capacity to enhance security and stability across Afghanistan. During the June 1 through November 30, 2015, reporting...aerial fires. Nonetheless, the AAF will require coalition support for several years in order to build institutional functions and continue development...during this reporting period have been positive steps towards institutional change within the ministries. After a government-wide overhaul of the

  16. Surface-stabilized gold nanocatalysts

    DOEpatents

    Dai, Sheng [Knoxville, TN; Yan, Wenfu [Oak Ridge, TN

    2009-12-08

    A surface-stabilized gold nanocatalyst includes a solid support having stabilizing surfaces for supporting gold nanoparticles, and a plurality of gold nanoparticles having an average particle size of less than 8 nm disposed on the stabilizing surfaces. The surface-stabilized gold nanocatalyst provides enhanced stability, such as at high temperature under oxygen containing environments. In one embodiment, the solid support is a multi-layer support comprising at least a first layer having a second layer providing the stabilizing surfaces disposed thereon, the first and second layer being chemically distinct.

  17. Curcumin Encapsulated in Milk Exosomes Resists Human Digestion and Possesses Enhanced Intestinal Permeability in Vitro.

    PubMed

    Vashisht, Monika; Rani, Payal; Onteru, Suneel Kumar; Singh, Dheer

    2017-11-01

    Exosomes, the extracellular secretary nano-vesicles, act as carriers of biomolecules to the target cells. They exhibit several attributes of an efficient drug delivery system. Curcumin, despite having numerous bioactive and therapeutic properties, has limited pharmaceutical use due to its poor water solubility, stability, and low systemic bioavailability. Hence, this study aims to enhance the therapeutic potential of curcumin, a model hydrophobic drug, by its encapsulation into milk exosomes. In the present study, we investigated the stability of free curcumin and exosomal curcumin in PBS and in vitro digestive processes. Additionally, their uptake and trans-epithelial transport were studied on Caco-2 cells. Curcumin in milk exosomes had higher stability in PBS, sustained harsh digestive processes, and crossed the intestinal barrier than free curcumin. In conclusion, the encapsulation of curcumin into the exosomes enhances its stability, solubility, and bioavailability. Therefore, the present study demonstrated that milk exosomes act as stable oral drug delivery vehicles.

  18. Bacterial lipopolysaccharide binding enhances virion stability and promotes environmental fitness of an enteric virus

    PubMed Central

    Robinson, Christopher M.; Jesudhasan, Palmy R.; Pfeiffer, Julie K.

    2014-01-01

    Summary Enteric viruses, including poliovirus and reovirus, encounter a vast microbial community in the mammalian gastrointestinal tract, which has been shown to promote virus replication and pathogenesis. Investigating the underlying mechanisms, we find that poliovirus binds bacterial surface polysaccharides, which enhances virion stability and cell attachment by increasing binding to the viral receptor. Additionally, we identified a poliovirus mutant, VP1-T99K, with reduced lipopolysaccharide (LPS) binding. Although T99K and WT poliovirus cell attachment, replication and pathogenesis in mice are equivalent, following peroral inoculation of mice, VP1-T99K poliovirus was unstable in feces. Consequently, the ratio of mutant virus in feces is reduced following additional cycles of infection in mice. Thus, the mutant virus incurs a fitness cost when environmental stability is a factor. These data suggest that poliovirus binds bacterial surface polysaccharides, enhancing cell attachment and environmental stability, potentially promoting transmission to a new host. PMID:24439896

  19. The influence of the war on perinatal and maternal mortality in Bosnia and Herzegovina.

    PubMed

    Fatusić, Z; Kurjak, A; Grgić, G; Tulumović, A

    2005-10-01

    To investigate the influence of the war on perinatal and maternal mortality during the war conflict in Bosnia and Herzegovina. In a retrospective study we analysed perinatal and maternal mortality in the pre-war period (1988-1991), the war period (1992-1995) and the post-war period (1996-2003). We also analysed the number of deliveries, the perinatal and maternal mortality rates and their causes. During the analysed period we had a range of 3337-6912 deliveries per year, with a decreased number in the war period. During the war period and immediately after the war, the perinatal mortality rate increased to 20.9-26.3% (average 24.28%). After the war the rate decreased to 8.01% in 2003 (p < 0.05). Maternal mortality before the war was 39/100,000 deliveries, during the war it increased to 65/100,000 and after the war it decreased to 12/100,000 deliveries (p < 0.05). The increase in maternal mortality during the war was because of an increased number of uterine ruptures, sepsis and bleeding due to shell injury of pregnant women. During the war we could expect a decreased number of deliveries, and an increased rate of perinatal and maternal mortality and preterm deliveries due to: inadequate nutrition, stress factors (life in refugee's centers, bombing, deaths of relatives, uncertain future...), and break down of the perinatal care system (lack of medical staff, impossibility of collecting valid health records, particularly perinatal information, and the destruction of medical buildings).

  20. Reuse fo a Cold War Surveillance Drone to Flight Test a NASA Rocket Based Combined Cycle Engine

    NASA Technical Reports Server (NTRS)

    Brown, T. M.; Smith, Norm

    1999-01-01

    Plans for and early feasibility investigations into the modification of a Lockheed D21B drone to flight test the DRACO Rocket Based Combined Cycle (RBCC) engine are discussed. Modifications include the addition of oxidizer tanks, modern avionics systems, actuators, and a vehicle recovery system. Current study results indicate that the D21B is a suitable candidate for this application and will allow demonstrations of all DRACO engine operating modes at Mach numbers between 0.8 and 4.0. Higher Mach numbers may be achieved with more extensive modification. Possible project risks include low speed stability and control, and recovery techniques.

  1. Kurdistan Region, Asia as seen from STS-58

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Lake Urmia (Orumiyeh) in the high desert palteau of northwest Iran dominates the center of the northeast-looking view. The left edge of the view cuts Lake Van in eastern Turkey. The Caucasus mountains in war-torn Georgia appear just beyond. Mount Ararat is a major peak north of Lake Van. The Caspian Sea, an international body of water, stretches across the top right of the view. Countries bordering the Caspian are Iran in the south, Kazakhstan in the west, and Russia and Azerbaijan in the west. The shuttle stabilizer, OMS pods and open payload bay can also be seen just above the horizon.

  2. Trusses Of Tensegrity Type In A Concept Of Train Station Renovation In Żary

    NASA Astrophysics Data System (ADS)

    Lechocka, Paulina

    2015-09-01

    The first railway station in Żary was built in 1843 in Germany. After the Second World War and years of socialism in Poland the meaning of railway decreased and its technical condition deteriorated. Now the building needs renovation and change of function. Tensegrity structures may be useful in renovation of platforms shelter. They are strut and tie construction, in which there is self-stabilization between compressed and tensioned elements. Conception of new platform shelter is based on exemplary tensegrity module consist of three struts and nine cables (called "Simplex"). Tensegrity would make railway station more modern, but not cover its original elevation.

  3. Wavelet modeling and prediction of the stability of states: the Roman Empire and the European Union

    NASA Astrophysics Data System (ADS)

    Yaroshenko, Tatyana Y.; Krysko, Dmitri V.; Dobriyan, Vitalii; Zhigalov, Maksim V.; Vos, Hendrik; Vandenabeele, Peter; Krysko, Vadim A.

    2015-09-01

    How can the stability of a state be quantitatively determined and its future stability predicted? The rise and collapse of empires and states is very complex, and it is exceedingly difficult to understand and predict it. Existing theories are usually formulated as verbal models and, consequently, do not yield sharply defined, quantitative prediction that can be unambiguously validated with data. Here we describe a model that determines whether the state is in a stable or chaotic condition and predicts its future condition. The central model, which we test, is that growth and collapse of states is reflected by the changes of their territories, populations and budgets. The model was simulated within the historical societies of the Roman Empire (400 BC to 400 AD) and the European Union (1957-2007) by using wavelets and analysis of the sign change of the spectrum of Lyapunov exponents. The model matches well with the historical events. During wars and crises, the state becomes unstable; this is reflected in the wavelet analysis by a significant increase in the frequency ω (t) and wavelet coefficients W (ω, t) and the sign of the largest Lyapunov exponent becomes positive, indicating chaos. We successfully reconstructed and forecasted time series in the Roman Empire and the European Union by applying artificial neural network. The proposed model helps to quantitatively determine and forecast the stability of a state.

  4. Enhanced Engine Control for Emergency Operation

    NASA Technical Reports Server (NTRS)

    Litt, Jonathan S.

    2012-01-01

    C-MAPSS40k engine simulation has been developed and is available to the public. The authenticity of the engine performance and controller enabled the development of realistic enhanced control modes through controller modification alone. Use of enhanced control modes improved stability and control of an impaired aircraft. - Fast Response is useful for manual manipulation of the throttles - Use of Fast Response improved stability as part of a yaw rate feedback system. - Use of Overthrust shortened takeoff distance, but was generally useful in flight, too. Initial lack of pilot familiarity resulted in discomfort, especially with yaw rate feedback, but that was the only drawback, overall the pilot found the enhanced modes very helpful.

  5. Effectiveness and specificity of a classroom-based group intervention in children and adolescents exposed to war in Lebanon.

    PubMed

    Karam, Elie G; Fayyad, John; Nasser Karam, Aimee; Cordahi Tabet, Caroline; Melhem, Nadine; Mneimneh, Zeina; Dimassi, Hani

    2008-01-01

    The purpose of this study was to examine the effectiveness and specificity of a classroom-based psychosocial intervention after war. All students (n=2500) of six villages in Southern Lebanon designated as most heavily exposed to war received a classroom-based intervention delivered by teachers, consisting of cognitive-behavioural and stress inoculation training strategies. A random sample of treated students (n=101) and a matched control group (n=93) were assessed one month post-war and one year later. Mental disorders and psychosocial stressors were assessed using the Diagnostic Interview for Children and Adolescents - Revised with children and parents. War exposure was measured using the War Events Questionnaire. The prevalence of major depressive disorder (MDD), separation anxiety disorder (SAD) and post-traumatic stress disorder (PTSD) was examined pre-war, one month post-war (pre-intervention), and one year post-war. Specificity of treatment was determined by rating teachers' therapy diaries. The rates of disorders peaked one month post-war and decreased over one year. There was no significant effect of the intervention on the rates of MDD, SAD or PTSD. Post-war MDD, SAD and PTSD were associated with pre-war SAD and PTSD, family violence parameters, financial problems and witnessing war events. These findings have significant policy and public health implications, given current practices of delivering universal interventions immediately post-war.

  6. The Effect of War on Children.

    ERIC Educational Resources Information Center

    Goldson, Edward

    1996-01-01

    This paper discusses the effects of modern war on children in the 20th century, focusing on direct and indirect effects of World War II, Vietnam War, war in Afghanistan, conflicts in Africa and in Central America, and Persian Gulf War. The paper notes the devastating effects on children of disruption of education and other public services in…

  7. Resurrecting Limited War Theory

    DTIC Science & Technology

    2008-05-01

    indirectly with an appreciation of the principles and guidelines for limited war. 15. SUBJECT TERMS Limited War, Political Objectives, Total War...conflict between other nations may require the United States to act indirectly with an appreciation of the principles and guidelines for limited war...in war, echoing Clausewitz’s principle of political primacy. Like Clausewitz, he was also a student of

  8. Women and War, Children and War: Stretching the Bonds of Caregiving.

    ERIC Educational Resources Information Center

    McNamee, Abigail S.

    Many things stretch the bonds between caregiver and child, such as war, stress, and trauma. This paper reviews the literature on children who are in direct contact with war or indirect contact with war through television or others' conversations. It also describes the effects of war on children and their families, and children's psychological…

  9. Examining the Audio Images of War: Lyrical Perspectives of America's Major Military Crusades, 1914-1991.

    ERIC Educational Resources Information Center

    Cooper, B. Lee

    1992-01-01

    Explores the differing lyrical perceptions of war and military activity depicted in popular songs during World War I, World War II, the Vietnam War, and the Persian Gulf War. The role of music in reinforcing patriotism is discussed, as well as the antiwar sentiment of the Vietnam era. (31 references) (LRW)

  10. As-grown graphene/copper nanoparticles hybrid nanostructures for enhanced intensity and stability of surface plasmon resonance

    PubMed Central

    Li, Yun-Fei; Dong, Feng-Xi; Chen, Yang; Zhang, Xu-Lin; Wang, Lei; Bi, Yan-Gang; Tian, Zhen-Nan; Liu, Yue-Feng; Feng, Jing; Sun, Hong-Bo

    2016-01-01

    The transfer-free fabrication of the high quality graphene on the metallic nanostructures, which is highly desirable for device applications, remains a challenge. Here, we develop the transfer-free method by direct chemical vapor deposition of the graphene layers on copper (Cu) nanoparticles (NPs) to realize the hybrid nanostructures. The graphene as-grown on the Cu NPs permits full electric contact and strong interactions, which results in a strong localization of the field at the graphene/copper interface. An enhanced intensity of the localized surface plasmon resonances (LSPRs) supported by the hybrid nanostructures can be obtained, which induces a much enhanced fluorescent intensity from the dye coated hybrid nanostructures. Moreover, the graphene sheets covering completely and uniformly on the Cu NPs act as a passivation layer to protect the underlying metal surface from air oxidation. As a result, the stability of the LSPRs for the hybrid nanostructures is much enhanced compared to that of the bare Cu NPs. The transfer-free hybrid nanostructures with enhanced intensity and stability of the LSPRs will enable their much broader applications in photonics and optoelectronics. PMID:27872494

  11. All-Cause Mortality Among US Veterans of the Persian Gulf War: 13-Year Follow-up.

    PubMed

    Barth, Shannon K; Kang, Han K; Bullman, Tim

    2016-11-01

    We determined cause-specific mortality prevalence and risks of Gulf War deployed and nondeployed veterans to determine if deployed veterans were at greater risk than nondeployed veterans for death overall or because of certain diseases or conditions up to 13 years after conflict subsided. Follow-up began when the veteran left the Gulf War theater or May 1, 1991, and ended on the date of death or December 31, 2004. We studied 621   901 veterans who served in the 1990-1991 Persian Gulf War and 746   247 veterans who served but were not deployed during the Gulf War. We used Cox proportional hazard models to calculate rate ratios adjusted for age at entry to follow-up, length of follow-up, race, sex, branch of service, and military unit. We compared the mortality of (1) Gulf War veterans with non-Gulf War veterans and (2) Gulf War army veterans potentially exposed to nerve agents at Khamisiyah in March 1991 with those not exposed. We compared standardized mortality ratios of deployed and nondeployed Gulf War veterans with the US population. Male Gulf War veterans had a lower risk of mortality than male non-Gulf War veterans (adjusted rate ratio [aRR] = 0.97; 95% confidence interval [CI], 0.95-0.99), and female Gulf War veterans had a higher risk of mortality than female non-Gulf War veterans (aRR = 1.15; 95% CI, 1.03-1.28). Khamisiyah-exposed Gulf War army veterans had >3 times the risk of mortality from cirrhosis of the liver than nonexposed army Gulf War veterans (aRR = 3.73; 95% CI, 1.64-8.48). Compared with the US population, female Gulf War veterans had a 60% higher risk of suicide and male Gulf War veterans had a lower risk of suicide (standardized mortality ratio = 0.84; 95% CI, 0.80-0.88). The vital status and mortality risk of Gulf War and non-Gulf War veterans should continue to be investigated.

  12. Prevalence of Gulf war veterans who believe they have Gulf war syndrome: questionnaire study

    PubMed Central

    Chalder, T; Hotopf, M; Unwin, C; Hull, L; Ismail, K; David, A; Wessely, S

    2001-01-01

    Objectives To determine how many veterans in a random sample of British veterans who served in the Gulf war believe they have “Gulf war syndrome,” to examine factors associated with the presence of this belief, and to compare the health status of those who believe they have Gulf war syndrome with those who do not. Design Questionnaire study asking British Gulf war veterans whether they believe they have Gulf war syndrome and about symptoms, fatigue, psychological distress, post-traumatic stress, physical functioning, and their perception of health. Participants 2961 respondents to questionnaires sent out to a random sample of 4250 Gulf war veterans (69.7%). Main outcome measure The proportion of veterans who believe they have Gulf war syndrome. Results Overall, 17.3% (95% confidence interval 15.9 to 18.7) of the respondents believed they had Gulf war syndrome. The belief was associated with the veteran having poor health, not serving in the army when responding to the questionnaire, and having received a high number of vaccinations before deployment to the Gulf. The strongest association was knowing another person who also thought they had Gulf war syndrome. Conclusions Substantial numbers of British Gulf war veterans believe they have Gulf war syndrome, which is associated with psychological distress, a high number of symptoms, and some reduction in activity levels. A combination of biological, psychological, and sociological factors are associated with the belief, and these factors should be addressed in clinical practice. What is already known on this topicThe term Gulf war syndrome has been used to describe illnesses and symptoms experienced by veterans of the 1991 Gulf warConcerns exist over the validity of Gulf war syndrome as a unique entityWhat this study adds17% of Gulf war veterans believe they have Gulf war syndromeHolding the belief is associated with worse health outcomesKnowing someone else who believes they have Gulf war syndrome and receiving more vaccinations were associated with holding the belief PMID:11532836

  13. All-Cause Mortality Among US Veterans of the Persian Gulf War

    PubMed Central

    Kang, Han K.; Bullman, Tim

    2016-01-01

    Objective: We determined cause-specific mortality prevalence and risks of Gulf War deployed and nondeployed veterans to determine if deployed veterans were at greater risk than nondeployed veterans for death overall or because of certain diseases or conditions up to 13 years after conflict subsided. Methods: Follow-up began when the veteran left the Gulf War theater or May 1, 1991, and ended on the date of death or December 31, 2004. We studied 621   901 veterans who served in the 1990-1991 Persian Gulf War and 746   247 veterans who served but were not deployed during the Gulf War. We used Cox proportional hazard models to calculate rate ratios adjusted for age at entry to follow-up, length of follow-up, race, sex, branch of service, and military unit. We compared the mortality of (1) Gulf War veterans with non–Gulf War veterans and (2) Gulf War army veterans potentially exposed to nerve agents at Khamisiyah in March 1991 with those not exposed. We compared standardized mortality ratios of deployed and nondeployed Gulf War veterans with the US population. Results: Male Gulf War veterans had a lower risk of mortality than male non–Gulf War veterans (adjusted rate ratio [aRR] = 0.97; 95% confidence interval [CI], 0.95-0.99), and female Gulf War veterans had a higher risk of mortality than female non–Gulf War veterans (aRR = 1.15; 95% CI, 1.03-1.28). Khamisiyah-exposed Gulf War army veterans had >3 times the risk of mortality from cirrhosis of the liver than nonexposed army Gulf War veterans (aRR = 3.73; 95% CI, 1.64-8.48). Compared with the US population, female Gulf War veterans had a 60% higher risk of suicide and male Gulf War veterans had a lower risk of suicide (standardized mortality ratio = 0.84; 95% CI, 0.80-0.88). Conclusion: The vital status and mortality risk of Gulf War and non–Gulf War veterans should continue to be investigated. PMID:28123229

  14. War-related experiences of former child soldiers in northern Uganda: comparison with non-recruited youths.

    PubMed

    Vindevogel, Sofie; Schryver, Maarten de; Broekaert, Eric; Derluyn, Ilse

    2013-11-01

    Armed conflict imposes huge hardship on young people living in war zones. This study assessed former child soldiers' experience and perception of stress in common war events during the armed conflict in northern Uganda and compares it with their non-recruited counterparts. To investigate whether child soldiers experienced more severe exposure to war events, and explore how war might affect youths differently, depending on the co-occurrence of these events. The study was undertaken in four northern Ugandan districts in 22 secondary schools with a sample size of 981 youths, about half of whom had been child soldiers. The participants completed a questionnaire on socio-demographic characteristics and stressful war events which was analyzed using descriptive statistics, a probabilistic index and correlation network analysis. Former child soldiers had significantly greater experience of war events than their non-recruited counterparts. The violence of war is more central in their experience and perception of stress, whereas the scarcity of resources and poor living conditions are most central for non-recruited participants. The extent to which a war event, such as separation from the family, is perceived as stressful depends on the experience and perception of other stressful war events, such as confrontation with war violence for former child soldiers and life in an Internally Displaced Persons' camp for non-recruited participants. The network approach permitted demonstration of the many ways in which war-affected youths encounter and appraise stressful war events. War events might function as moderators or mediators of the effect that other war events exert on the lives and well-being of young people living in war zones. This demands comprehensive and individualized assessment.

  15. Active war in Sri Lanka: Children's war exposure, coping, and posttraumatic stress disorder symptom severity.

    PubMed

    Soysa, Champika K; Azar, Sandra T

    2016-01-01

    Posttraumatic stress disorder (PTSD) in response to active war is understudied among Sinhalese children in Sri Lanka. We investigated PTSD symptom severity in children using child (n = 60) and mother (n = 60) reports; child-reported war exposure and coping; as well as self-reported maternal PTSD symptom severity. The study addressed active war in 2 rural locations (acute and chronic community war exposure). Child-reports were significantly greater than mother-reports of child PTSD symptom severity. Furthermore, children's war exposure, child-reported and mother-reported child PTSD symptom severity, and maternal PTSD symptom severity were significantly greater in the acute versus chronic community war exposure location, but children's approach and avoidance coping did not significantly differ, indicating a potential ceiling effect. Children's war exposure significantly, positively predicted child-reported child PTSD symptom severity, controlling for age, gender, and maternal PTSD symptom severity, but only maternal PTSD symptom severity significantly, positively predicted mother-reported child PTSD symptom severity. Avoidance coping (in both acute and chronic war) significantly positively mediated the children's war exposure-child-reported child PTSD symptom severity relation, but not mother-reports of the same. Approach coping (in chronic but not acute war) significantly, positively mediated the children's war exposure-child-reported and mother-reported child PTSD symptom severity relations. We advanced the literature on long-term active war by confirming the value of children's self-reports, establishing that both approach and avoidance coping positively mediated the war-exposure-PTSD symptom severity relation, and that the mediation effect of approach coping was situationally moderated by acute verses chronic community war exposure among Sri Lankan children. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    This report contains papers on the following topics: NREN Security Issues: Policies and Technologies; Layer Wars: Protect the Internet with Network Layer Security; Electronic Commission Management; Workflow 2000 - Electronic Document Authorization in Practice; Security Issues of a UNIX PEM Implementation; Implementing Privacy Enhanced Mail on VMS; Distributed Public Key Certificate Management; Protecting the Integrity of Privacy-enhanced Electronic Mail; Practical Authorization in Large Heterogeneous Distributed Systems; Security Issues in the Truffles File System; Issues surrounding the use of Cryptographic Algorithms and Smart Card Applications; Smart Card Augmentation of Kerberos; and An Overview of the Advanced Smart Card Access Control System.more » Selected papers were processed separately for inclusion in the Energy Science and Technology Database.« less

  17. [The war at home: "war amenorrhea" in the First World War].

    PubMed

    Stukenbrock, Karin

    2008-01-01

    In 1917, the Göttingen gynaecologist Dietrich published a short article about a phenomenon which he called "war amenorrhea" ("Kriegsamenorrhoe"). The article attracted the attention of his colleagues. While the affected women did not pay much attention to their amenorrhea, the physicians considered the phenomenon a new disease which was mainly caused by the war. This new disease gave the gynaecologists the opportunity to present their specialty as a discipline with high relevance for medicine in times of war. Nevertheless, there was no consensus about the importance, the incidence, the diagnostic criteria, the causes and the appropriate therapy of"war amenorrhea". Although the gynaecologists failed to define a uniform clinical syndrome, they maintained the construction of "war amenorrhea" after the war and subsumed it under well known types of amenorrhea. We can conclude that under the conditions of war a new disease emerged which was not sharply defined.

  18. Trajectories of attachment in older age: interpersonal trauma and its consequences.

    PubMed

    Bachem, Rahel; Levin, Yafit; Solomon, Zahava

    2018-06-04

    Previous studies suggest that attachment insecurities may increase after trauma exposure, an effect documented only at a group level. This study explores the heterogeneity of changes over time and examines the associations of the nature of the traumatic event (interpersonal and nonpersonal), and its consequences (posttraumatic stress disorder [PTSD] and loneliness) with attachment trajectories. Two groups of Israeli veterans participated: 164 former prisoners-of-war and 185 combat veterans. Attachment was assessed at four points (1991-2015). Risk factors were evaluated in 1991. Using latent growth mixture modeling, trajectories of attachment insecurities were explored. Three avoidance trajectories (stability, decrease, inverse u-shaped) and two anxiety trajectories (stability, decrease) were identified. The inverse u-shaped avoidance trajectory was associated with captivity, humiliation, loneliness, and PTSD, and stable avoidance was associated with loneliness. Stable anxiety was associated with captivity and loneliness. Attachment insecurities can change during aging and persist decades after a trauma. Trauma-related risk factors are related to more deleterious trajectories.

  19. Uganda--rehabilitation, or redefinition of health services?

    PubMed

    Dodge, C P

    1986-01-01

    Uganda had one of the best health care delivery systems in Africa. The decade of misrule by Amin saw a collapse of the country and an exodus of doctors and other professions. The 1979 liberation war and subsequent political instability and insecurity further aggravated the poor health services then available. When political stability was temporarily restored in December 1980 the cash crop export sector took priority over social services and the health budget declined to only 3.5% compared to a former level of 7.5% of government budget. Emergencies in West Nile, Karamoja and the Luwero triangle continued to plague rehabilitation efforts upto 1985. Alternate strategies for improving health are proposed including female education, increased budget allocations, food and nutrition policy and health information. Uganda's prospect for rebuilding the health services has begun with immunization, control of diarrhoeal diseases, nutrition surveillance in Karamoja and an essential drugs programme, but the success of these is dependent upon political stability and improvement in overall security.

  20. Enhanced electrical stability of flexible indium tin oxide films prepared on stripe SiO 2 buffer layer-coated polymer substrates by magnetron sputtering

    NASA Astrophysics Data System (ADS)

    Yu, Zhi-nong; Zhao, Jian-jian; Xia, Fan; Lin, Ze-jiang; Zhang, Dong-pu; Leng, Jian; Xue, Wei

    2011-03-01

    The electrical stability of flexible indium tin oxide (ITO) films fabricated on stripe SiO 2 buffer layer-coated polyethylene terephthalate (PET) substrates by magnetron sputtering was investigated by the bending test. The ITO thin films with stripe SiO 2 buffer layer under bending have better electrical stability than those with flat SiO 2 buffer layer and without buffer layer. Especially in inward bending text, the ITO thin films with stripe SiO 2 buffer layer only have a slight resistance change when the bending radius r is not less than 8 mm, while the resistances of the films with flat SiO 2 buffer layer and without buffer layer increase significantly at r = 16 mm with decreasing bending radius. This improvement of electrical stability in bending test is due to the small mismatch factor α in ITO-SiO 2, the enhanced interface adhesion and the balance of residual stress. These results indicate that the stripe SiO 2 buffer layer is suited to enhance the electrical stability of flexible ITO film under bending.

  1. Plasma Density Effects on Toroidal Flow Stabilization of Edge Localized Modes

    NASA Astrophysics Data System (ADS)

    Cheng, Shikui; Zhu, Ping; Banerjee, Debabrata

    2016-10-01

    Recent EAST experiments have demonstrated mitigation and suppression of edge localized modes (ELMs) with toroidal rotation flow in higher collisionality regime, suggesting potential roles of plasma density. In this work, the effects of plasma density on the toroidal flow stabilization of the high- n edge localized modes have been extensively studied in linear calculations for a circular-shaped limiter H-mode tokamak, using the initial-value extended MHD code NIMROD. In the single MHD model, toroidal flow has a weak stabilizing effects on the high- n modes. Such a stabilization, however, can be significantly enhanced with the increase in plasma density. Furthermore, our calculations show that the enhanced stabilization of high- n modes from toroidal flow with higher edge plasma density persists in the 2-fluid MHD model. These findings may explain the ELM mitigation and suppression by toroidal rotation in higher collisionality regime due to the enhancement of plasma density obtained in EAST experiment. Supported by the National Magnetic Confinement Fusion Program of China under Grant Nos. 2014GB124002 and 2015GB101004, the 100 Talent Program and the President International Fellowship Initiative of Chinese Academy of Sciences.

  2. First War Syndrome: Military Culture, Professionalization, and Counterinsurgency Doctrine

    DTIC Science & Technology

    2010-02-01

    in Ivan Musicant, The Banana Wars: A History of U.S. Intervention in Latin America from the Spanish-A merican War to the Invasion of Panama, (New...the " banana wars," many Marines grew very comfortable with these conflicts and Corps’ role as de facto imperial police force. 2 289 Millet, pp. 278-280...focus on the " banana wars" under the leadership of World War I veterans like John Lejeune. See also Bickel, pg. 54-55. 157 The war predictably disrupted

  3. Bouncing Back From War Trauma: Resiliency in Global War on Terror’s Wounded Warriors

    DTIC Science & Technology

    2015-02-11

    Casualties of the Global War on Terror and Their Future Impact on Health Care and Society: A Looming Public Health Crisis .” Military Medicine 179 (April...Casualties of the Global War on Terror and Their Future Impact on Health Care and Society: A Looming Public Health Crisis .” Military Medicine 179...AIR WAR COLLEGE AIR UNIVERSITY BOUNCING BACK FROM WAR TRAUMA: RESILIENCY IN GLOBAL WAR ON TERROR’S WOUNDED WARRIORS by Katherine H

  4. Invalid corps.

    PubMed

    Lande, R Gregory

    2008-06-01

    This article explores America's historical experience with medical disability compensation programs during the Revolutionary War and the Civil War. Contemporary newspaper reports, complemented by book and journal articles, provide an understanding of the medical disability compensation programs offered during the Revolutionary War and the Civil War. Military planners, politicians, and service members struggled to develop a fair and balanced medical disability compensation program during the Revolutionary War and the Civil War. Based on America's extensive experience with the Civil War Invalid Corps, an alternative for motivated military personnel could be developed.

  5. Air Force, Cyberpower, Targeting: Airpower Lessons for an Air Force Cyberpower Targeting Theory

    DTIC Science & Technology

    2013-06-01

    apply in future war. Following World War I, Airmen at the Air Corps Tactical School (ACTS) developed an “Industrial Web Theory” for targeting to...throughout its use. The targeting theory was employed with mixed results from World War II through the Vietnam War. In the late 20th century, Colonel...A review of the Inter-War period, World War II, Korean War, and Desert Storm intends to evaluate airpower targeting theories in order to develop

  6. Enhanced Structural Stability and Photo Responsiveness of CH3 NH3 SnI3 Perovskite via Pressure-Induced Amorphization and Recrystallization.

    PubMed

    Lü, Xujie; Wang, Yonggang; Stoumpos, Constantinos C; Hu, Qingyang; Guo, Xiaofeng; Chen, Haijie; Yang, Liuxiang; Smith, Jesse S; Yang, Wenge; Zhao, Yusheng; Xu, Hongwu; Kanatzidis, Mercouri G; Jia, Quanxi

    2016-10-01

    An organic-inorganic halide CH 3 NH 3 SnI 3 perovskite with significantly improved structural stability is obtained via pressure-induced amorphization and recrystallization. In situ high-pressure resistance measurements reveal an increased electrical conductivity by 300% in the pressure-treated perovskite. Photocurrent measurements also reveal a substantial enhancement in visible-light responsiveness. The mechanism underlying the enhanced properties is shown to be associated with the pressure-induced structural modification. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Persuasive History: A Critical Comparison of Television's "Victory at Sea" and "The World at War."

    ERIC Educational Resources Information Center

    Mattheisen, Donald J.

    1992-01-01

    Discusses the television series "Victory at Sea" and "The World at War" and their use in teaching about World War II. Contrasts that war's glorious portrayal in "Victory at Sea" with the more ambiguous presentation of "The World at War." Suggests that students can learn a great deal about war and film itself…

  8. Middle Adolescents' Views of War and American Military Involvement in the Persian Gulf.

    ERIC Educational Resources Information Center

    Schroeder, Daniel F.; And Others

    1993-01-01

    Surveyed 189 eleventh graders to assess attitudes toward war in general and attitudes toward Persian Gulf War. Reactions to war were associated with gender, race, and school setting. Students in study were slightly less supportive of war, in general, but more supportive of Gulf War than were past subjects on conflicts of their day (Vietnam and…

  9. Combined Action Platoons in Vietnam

    DTIC Science & Technology

    2012-04-27

    Action Platoons; The US Marines’ Other War (New York: Praeger Publishers 1989) 2 Ibid. 3 Al Hemingway , Our War Was Different: Marine Combined...USMC Archives: Vietnam War Collection 1954-75 Box 7 folder 25 coll/3808 38 Al Hemingway , Our War Was...Platoons; The US Marines’ Other War (New York: Praeger Publishers 1989), 37 40 Al Hemingway , Our War Was Different: Marine Combined Action Platoons

  10. British Muslims and the UK government's 'war on terror' within: evidence of a clash of civilizations or emergent de-civilizing processes?

    PubMed

    Vertigans, Stephen

    2010-03-01

    In the immediate aftermath of the September 2001 attacks on America, defending civilization was quickly established at the core of the 'war on terror'. Unintentionally or otherwise this incorporation of civilization connected with Samuel Huntington's 'Clash of Civilizations' thesis. Within the 'war on terror' the dark side of counterterrorism has become apparent through international practices like extrajudicial killing, extraordinary rendition and torture. The impact of Western governments' policies upon their indigenous Muslim populations has also been problematic but social and political analysis has been relatively limited. This paper seeks to help address the scarcity of sociological contributions. Hidden costs of the UK government's attempts to utilize violence and enhance social constraints within the nation-state are identified. It is argued that although counterterrorism strategies are contributing to a self-fulfilling spiral of hatred that could be considered evidence in support of the 'Clash of Civilizations', the thesis is unhelpful when trying to grasp the underlying processes. Instead the paper draws upon Norbert Elias's application of the concepts of 'civilizing' and 'de-civilizing' to help improve levels of understanding about the processes and consequences of particular Muslim communities being targeted by security forces. The paper concludes with an exploration of the majority of the population's acquiescence and willingness to accept restraints upon Muslims in order to safeguard their own security.

  11. Noise enhanced stability of a metastable state containing coupled Brownian particles

    NASA Astrophysics Data System (ADS)

    Singh, R. K.

    2017-05-01

    Dynamics of coupled Brownian particles with color correlated additive Gaussian colored noises in a metastable state is analyzed to study the phenomenon of noise enhanced stability. The lifetime of such a metastable state is found to depend on the noise correlations and initial conditions. Dynamics of the slow variable is analyzed using the method of adiabatic elimination in the weak color limit.

  12. Enhanced stabilization of Pb, Zn, and Cd in contaminated soils using oxalic acid-activated phosphate rocks.

    PubMed

    Zhang, Zhuo; Guo, Guanlin; Wang, Mei; Zhang, Jia; Wang, Zhixin; Li, Fasheng; Chen, Honghan

    2018-01-01

    Phosphate amendments, especially phosphate rock (PR), are one of the most commonly used materials to stabilize heavy metals in contaminated soils. However, most of PR reserve consists of low-grade ore, which limits the efficiency of PR for stabilizing heavy metals. This study was to enhance the stabilization of heavy metals through improving the available phosphorous (P) release of PR by oxalic acid activation. Raw PR and activated PR (APR) were characterized by scanning electron microscopy-energy dispersive X-ray spectroscopy (SEM-EDS), X-ray powder diffraction (XRD), Brunauer-Emmett-Teller (BET) surface analysis, and laser diffraction to determine the changes of structure and composition of APR. The stabilization effectiveness of lead (Pb), zinc (Zn), and cadmium (Cd) in soils by APR was investigated through toxicity leaching test and speciation analysis. The results indicated that after treatment by oxalic acid, (1) the crystallinity of the fluorapatite phase of PR transformed into the weddellite phase; (2) the surface area of PR increased by 37%; (3) the particle size of PR became homogenized (20-70 μm); and (4) the available P content in PR increased by 22 times. These changes of physicochemical characteristics of PR induced that APR was more effective to transform soil heavy metals from the non-residual fraction to the residual fraction and enhance the stabilization efficiency of Pb, Zn, and Cd than PR. These results are significant for the future use of low-grade PR to stabilize heavy metals.

  13. Chitosan based atorvastatin nanocrystals: effect of cationic charge on particle size, formulation stability, and in-vivo efficacy

    PubMed Central

    Kurakula, Mallesh; El-Helw, AM; Sobahi, Tariq R; Abdelaal, Magdy Y

    2015-01-01

    Cationic charged chitosan as stabilizer was evaluated in preparation of nanocrystals using probe sonication method. The influence of cationic charge densities of chitosan (low CSL, medium CSM, high CSH molecular weights) and Labrasol® in solubility enhancement and modifying the release was investigated, using atorvastatin (ATR) as poorly soluble model drug. Compared to CSM and CSH; low cationic charge of CSL acted as both electrostatic and steric stabilizer by significant size reduction to 394 nm with charge of 21.5 meV. Solubility of ATR-CSL increased to 60-fold relative to pure ATR and ATR-L. Nanocrystals were characterized for physiochemical properties. Scanning electron microscopy revealed scaffold-like structures with high surface area. X-ray powder diffractometry and differential scanning calorimetry revealed crystalline to slight amorphous state changes after cationic charge size reduction. Fourier transform-infrared spectra indicated no potent drug-excipient interactions. The enhanced dissolution profile of ATR-CSL indicates that sustained release was achieved compared with ATR-L and Lipitor®. Anti-hyperlipidemic performance was pH dependent where ATR-CSL exhibited 2.5-fold higher efficacy at pH 5 compared to pH 6 and Lipitor®. Stability studies indicated marked changes in size and charge for ATR-L compared to ATR-CSL exemplifying importance of the stabilizer. Therefore, nanocrystals developed with CSL as a stabilizer is a promising choice to enhance dissolution, stability, and in-vivo efficacy of major Biopharmaceutical Classification System II/IV drugs. PMID:25609947

  14. Leveraging Venture Capital and Commercial Business: Enhancing Stability Operations

    DTIC Science & Technology

    2011-03-24

    Economic Stability Operations have emerged as a new element of United States national strategic power. The creation of jobs, through commercial...examine the key strategic factors influencing long-term economic stability following the withdrawal of combat forces. This paper provides a model for

  15. 21 CFR 864.9400 - Stabilized enzyme solution.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Products Used In Establishments That Manufacture Blood and Blood Products § 864.9400 Stabilized enzyme solution. (a) Identification. A stabilized enzyme solution is a reagent intended for medical purposes that is used to enhance the reactivity of red blood...

  16. 21 CFR 864.9400 - Stabilized enzyme solution.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Products Used In Establishments That Manufacture Blood and Blood Products § 864.9400 Stabilized enzyme solution. (a) Identification. A stabilized enzyme solution is a reagent intended for medical purposes that is used to enhance the reactivity of red blood...

  17. 21 CFR 864.9400 - Stabilized enzyme solution.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Products Used In Establishments That Manufacture Blood and Blood Products § 864.9400 Stabilized enzyme solution. (a) Identification. A stabilized enzyme solution is a reagent intended for medical purposes that is used to enhance the reactivity of red blood...

  18. Enhanced Product Stability in the Hammerhead Ribozyme†

    PubMed Central

    Shepotinovskaya, Irina; Uhlenbeck, Olke C.

    2010-01-01

    The rate of dissociation of P1, the 5′ product of hammerhead cleavage, is 100–300-fold slower in full-length hammerheads than in hammerheads that either lack or have disrupting mutations in the loop-loop tertiary interaction. The added stability requires the presence of residue 17 at the 3′ terminus of P1 but not the 2′, 3′ terminal phosphate. Since residue 17 is buried within the catalytic core of the hammerhead in the x-ray structure, we propose that the enhanced P1 stability is the result of the cooperative folding of the hammerhead around this residue. However, since the P1 is fully stabilized above 2.5 mM MgCl2 while hammerhead activity continues to increase with increasing MgCl2, it is clear that the hammerhead structure in the transition state must differ from that of the product complex. The product stabilization assay is used to test our earlier proposal that different tertiary interactions modulate the cleavage rate by differentially stabilizing the core. PMID:20423112

  19. Enhanced emulsifying properties of wood-based cellulose nanocrystals as Pickering emulsion stabilizer.

    PubMed

    Gong, Xiaoyu; Wang, Yixiang; Chen, Lingyun

    2017-08-01

    Cellulose nanocrystals are hydrophilic nanomaterials, which limits their applications as interfacial compounds. Herein, we propose using modified wood-based cellulose nanocrystals as Pickering emulsion stabilizer. Wood cellulose was consecutively oxidized and modified with phenyltrimethylammonium chloride to create hydrophobic domains comprised of phenyl groups. These modified oxidized cellulose nanocrystals (m-O-CNCs) were homogeneous/electrostatically stable in water and they can stabilize O/W Pickering emulsions. The dispersed phase volume fraction (DPVF) of the Pickering emulsion was 0.7 at around 1.5g/L, whereas the tween-20 control needed a 13-fold greater concentration to have a similar DPVR. In addition, these m-O-CNC stabilized Pickering emulsions also showed good mechanical and thermal stability against centrifugation and heat, as well as size controllability. In terms of stability, size controllability, surfactant-free status, these m-O-CNCs possess superior and enhanced emulsifying properties. Future research for these new interfacial materials have potential in applications, for personal care, cosmetic and pharmaceutic industries. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Intergenerational effects of war trauma among Palestinian families mediated via psychological maltreatment.

    PubMed

    Palosaari, Esa; Punamäki, Raija-Leena; Qouta, Samir; Diab, Marwan

    2013-11-01

    We tested the hypothesis that intergenerational effects of parents' war trauma on offspring's attachment and mental health are mediated by psychological maltreatment. Two hundred and forty children and their parents were sampled from a war-prone area, Gaza, Palestine. The parents reported the number and type of traumatic experiences of war they had had during their lifetime before the child's birth and during a current war when the child was 10-12 years old. The children reported their war traumas, experiences of psychological maltreatment, attachment security, and symptoms of posttraumatic stress (PTSS), depression, and aggression. The direct and indirect intergenerational effects of war trauma were tested in structural equation models. The hypotheses were confirmed for father's past war exposure, and disconfirmed for mother's war exposure. The father's past war trauma had a negative association with attachment security and positive association with the child's mental health problems mediated by increased psychological maltreatment. In contrast, the mother's past war trauma had a negative association with the child's depression via decreased psychological maltreatment. The mother's current war trauma had a negative association with the child's depression and aggression via decreased psychological maltreatment. Among fathers, past war exposure should be considered as a risk factor for psychological maltreatment of children and the associated attachment insecurity and mental health problems. Among mothers, war exposure as such could be given less clinical attention than PTSS in the prevention of psychological maltreatment of children. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. Stability of the Baseline Holder in Readout Circuits For Radiation Detectors

    PubMed Central

    Chen, Y.; Cui, Y.; O’Connor, P.; Seo, Y.; Camarda, G. S.; Hossain, A.; Roy, U.; Yang, G.; James, R. B.

    2016-01-01

    Baseline holder (BLH) circuits are used widely to stabilize the analog output of application-specific integrated circuits (ASICs) for high-count-rate applications. The careful design of BLH circuits is vital to the overall stability of the analog-signal-processing chain in ASICs. Recently, we observed self-triggered fluctuations in an ASIC in which the shaping circuits have a BLH circuit in the feedback loop. In fact, further investigations showed that methods of enhancing small-signal stabilities cause an even worse situation. To resolve this problem, we used large-signal analyses to study the circuit’s stability. We found that a relatively small gain for the error amplifier and a small current in the non-linear stage of the BLH are required to enhance stability in large-signal analysis, which will compromise the properties of the BLH. These findings were verified by SPICE simulations. In this paper, we present our detailed analysis of the BLH circuits, and propose an improved version of them that have only minimal self-triggered fluctuations. We summarize the design considerations both for the stability and the properties of the BLH circuits. PMID:27182081

  2. Z-scheme Ag3PO4/POM/GO heterojunction with enhanced photocatalytic performance for degradation and water splitting.

    PubMed

    Liu, Guodong; Zhao, Xinfu; Zhang, Jian; Liu, Shaojie; Sha, Jingquan

    2018-05-01

    To develop solar light-driven photocatalysts with high activity and structural stability, Ag3PO4/POM/GO heterojunction has been successfully prepared by a facile method at room temperature. Ag3PO4/POM/GO shows remarkably enhanced activity and stability for photocatalytic degradation and H2 production from water-splitting under simulated solar light. The degradation rate of Ag3PO4/POM/GO is 1.8 times and 1.2 times those of Ag3PO4 and Ag3PO4/POMs, respectively. H2 production using Ag3PO4/POM/GO is 2.0 times that of Ag3PO4/GO. The enhanced photocatalytic performance of Ag3PO4/POM/GO is attributed to the increased surface area, electronegativity and structure stability. The Z-scheme system of Ag3PO4/POM/GO effectively promotes charge separation, resulting in enhanced photocatalytic performance under simulated solar light.

  3. Enhancing Resilience through Post-Deployment Decompression: A Softer Approach to Sharpening the Warrior Edge

    DTIC Science & Technology

    2012-04-25

    of burnout , psychological stress , and physical danger due to impaired functional abilities.” --CJCSI 3405.01 (Chairman’s Total Force Fitness...tenuous transition from combat to family life and its reciprocal, coping with the loss of loved ones or the horror of past experiences, and the stress ...2010. Hoge, Charles W. “Interventions for War-Related Posttraumatic Stress Disorder: Meeting Veterans Where They Are.” Journal of the American Medical

  4. Children at the Front: A Different View of the War on Alcohol and Drugs. The CWLA North American Commission on Chemical Dependency and Child Welfare. Final Report and Recommendations.

    ERIC Educational Resources Information Center

    Child Welfare League of America, Inc., Washington, DC.

    This report explores the impact of alcohol and drug problems on the children and families served by the child welfare system and outlines a comprehensive strategy to better respond to their needs. It contains more than 100 policy and action recommendations to enhance services to children and families affected by alcohol and other drugs (AOD), to…

  5. Moral Support, Strategic Reasoning, or Domestic Politics: America’s Continual Support to Israel

    DTIC Science & Technology

    2007-12-01

    were enhanced by key events to include the Eichmann trial, the Six-Day War, and popular cultural influences, which contributed to the remembrance of...the Holocaust and support for Israel.46 The Eichmann trail was one event that undoubtedly produced a growing awareness of the Holocaust memory for...not only America but the world as well. Although the facts of the Holocaust were always available to the public, the Eichmann trail reiterated

  6. Ain't Gonna Study War No More? Explorations of War through Picture Books

    ERIC Educational Resources Information Center

    Crawford, Patricia A.; Roberts, Sherron Killingsworth

    2009-01-01

    At the height of the Vietnam War, Down by the Riverside was transformed from a traditional folk song to a popular anti-war anthem. The raucous and repetitive chorus, "I ain't gonna study war no more ...," became a rallying cry for those who wanted nothing to do with the war and the pain and controversy that surrounded it. Although it seems…

  7. Outcomes of primary repair and primary anastomosis in war-related colon injuries.

    PubMed

    Vertrees, Amy; Wakefield, Matthew; Pickett, Chris; Greer, Lauren; Wilson, Abralena; Gillern, Sue; Nelson, Jeffery; Aydelotte, Jayson; Stojadinovic, Alexander; Shriver, Craig

    2009-05-01

    The role of primary repair (PR) of modern day war-related colon injuries remains controversial. Retrospective review of medical records of combat-wounded soldiers with colon injuries sustained during March 2003 to August 2006 was conducted. Injuries were analyzed according to location: right (n = 30), transverse (n = 13), and left (n = 24) sided colon injuries. Two-tailed Fisher's Exact or chi tests were used for statistical analysis. Seventy-seven soldiers returned to Walter Reed Army Medical Center with colon injuries suffered during Operations Enduring Freedom and Iraqi Freedom. Twelve patients with minor colon injuries were excluded. The remaining 65 patients (mean age, 28 +/- 7 years) sustained 67 colon injuries from secondary blast (n = 38); gunshot (n = 27); motor vehicle crash (n = 1) and crush injury (n = 1). Patients arrived at Walter Reed Army Medical Center 5 days (range, 2-16 days) after injury and damage control operations (n = 27, 42%), and were hospitalized for a median of 22 days (range, 1-306 days). Follow-up averaged 311 days (median, 198 days). PR was attempted in right (n = 18, 60%), transverse (n = 11, 85%), and left (n = 9, 38%) sided colon injuries. Delayed definitive treatment of colon injuries occurred in 42% of patients. Failure of repair occurred in 16% of patients and was more likely with concomitant pancreatic, stomach, splenic, diaphragm, and renal injuries. Overall morbidity for ostomy closure after primary ostomy formation was 30%, but increased to 75% for ostomy closure after primary anastomotic or repair failure. PR of war-related colon injuries can be performed safely in selected circumstances in the absence of concomitant organ injury. Delayed anastomosis can often be performed after damage control operations once the patient stabilizes. Ostomy closure complications are more likely after anastomotic failure.

  8. Social and traditional practices and their implications for family planning: a participatory ethnographic study in Renk, South Sudan.

    PubMed

    Elmusharaf, Khalifa; Byrne, Elaine; O'Donovan, Diarmuid

    2017-01-17

    Understanding what determines family size is crucial for programmes that aim to provide family planning services during and after conflicts. Recent research found that development agents in post conflict settings do not necessarily take time to understand the context adequately, translate their context understanding into programming, or adjust programming in the light of changes. South Sudan, a country that has been suffering from war for almost 50 years, has one of the highest maternal death rates and the lowest contraceptive utilization rates in the world. This research used Participatory Ethnographic Evaluation and Research (PEER) to provide a contextualised understanding of social and traditional practices and their implications for family planning. Fourteen women were recruited from 14 villages in Renk County in South Sudan in the period 2010-2012. They were trained to design research instruments, conduct interviews, collect narratives and stories and analyse data to identify, prioritize and address their maternal health concerns. As a result of wars, people are under pressure to increase their family sizes and thus increase the nation's population. This is to compensate for the men perished in war and the high child death rates. Large family size is regarded as a national obligation. Women are caught up in a vicious cycle of high fertility and a high rate of child mortality. Determinants of large family size include: 1) Social and cultural practices, 2) Clan lineage and 3) Compensation for loss of family members. Three strategies are used to increase family size: 1) Marry several women, 2) Husbands taking care of women, and 3) Financial stability. Consequences of big families include: 1) Financial burden, 2) Fear of losing children, 3) Borrowing children and 4) Husband shirking responsibility. The desire to have a big family will remain in South Sudan until families realise that their children will live longer, that their men will not be taken by the war, and that the costs of living will be met. In order to generate demand for family planning in South Sudan, priority should be given first to improve infant and child health.

  9. Effect of war on the menstrual cycle.

    PubMed

    Hannoun, Antoine B; Nassar, Anwar H; Usta, Ihab M; Zreik, Tony G; Abu Musa, Antoine A

    2007-04-01

    To study the effect of a short period of war on the menstrual cycles of exposed women. Six months after a 16-day war, women in exposed villages aged 15-45 years were asked to complete a questionnaire relating to their menstrual history at the beginning, 3 months after, and 6 months after the war. A control group, not exposed to war, was also interviewed. The data collected were analyzed to estimate the effect of war on three groups of women: those who stayed in the war zone for 3-16 days (Group A), those who were displaced within 2 days to safer areas (Group B), and women not exposed to war or displacement (Group C-control). More than 35% of women in Group A and 10.5% in Group B had menstrual aberrations 3 months after the cessation of the war. These percentages were significantly different from each other and from that in Group C (2.6%). Six months after the war most women regained their regular menstrual cycles with the exception of 18.6% in Group A. We found a short period of war, acting like an acute stressful condition, resulted in menstrual abnormalities in 10-35% of women and is probably related to the duration of exposure to war. This might last beyond the war time and for more than one or two cycles. In most women the irregular cycles reversed without any medical intervention. II.

  10. 46 CFR 308.539 - Application.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Facultative War Risk Cargo Insurance § 308.539 Application. (a) Preliminary request. Application for a... bind war risk in writing; for security reasons, if the applicant is submitting the order to bind war...

  11. Gender, Attitudes Toward War, and Masculinities in Japan.

    PubMed

    Morinaga, Yasuko; Sakamoto, Yuiri; Nakashima, Ken'ichiro

    2017-06-01

    Previous studies have argued that masculinity is linked to war. We conducted a web-based survey to examine relationships between gender, attitudes toward war, and masculinities within a sample of Japanese adults of both sexes ( N = 366). Our results indicated that while men were more likely than women to accept war, the relationship between attitudes toward war and masculinities was inconclusive. Moreover, the results suggested that favorable attitudes toward war among men could be attenuated by interpersonal orientations. Based on our findings, we recommend a reexamination of attitudes toward war within the Japanese population.

  12. Cavity Self-Stabilization and Enhancement of Laser Gyroscopes by (Coupled) Optical Resonators

    NASA Technical Reports Server (NTRS)

    Smith, David D.

    2006-01-01

    We analyze the effect of a highly dispersive element placed inside a modulated optical cavity on the frequency and amplitude of the modulation to determine the conditions for cavity self-stabilization and enhanced gyroscopic sensitivity. Hence, we model cavity rotation or instability by an arbitrary AM/FM modulation, and the dispersive element as a phase and amplitude filter. We find that anomalous dispersion may be used to self-stabilize a laser cavity, provided the magnitude of the group index of refraction is smaller than the phase index of refraction in the cavity. The optimal stabilization is found to occur when the group index is zero. Group indices with magnitudes larger than the phase index (both normal and anomalous dispersion) are found to enhance the sensitivity of a laser gyroscope to rotation. Furthermore, our results indicate that atomic media, even coherent superpositions in multilevel atoms, are not useful for these applications, because the amplitude and phase filters work against one another, i.e., decreasing the modulation frequency increases its amplitude and vice versa, with one exception: negative group indices whose magnitudes are larger than the phase index result in negative, but enhanced, beat frequencies. On the other hand, for optical resonators the dispersion reversal associated with critical coupling enables the amplitude and phase filters to work together under a greater variety of circumstances than for atomic media. We find that for single over-coupled resonators, or in the case of under-coupled coupled-resonator-induced absorption, the absorption and normal dispersion on-resonance increase the contrast and frequency of the beat-note, respectively, resulting in a substantial enhancement of the gyroscopic response. Moreover, for cavity self-stabilization, we propose the use of a variety of coupled-resonator induced transparency that is accompanied by anomalous dispersion.

  13. Is there an Iraq war syndrome? Comparison of the health of UK service personnel after the Gulf and Iraq wars.

    PubMed

    Horn, Oded; Hull, Lisa; Jones, Margaret; Murphy, Dominic; Browne, Tess; Fear, Nicola T; Hotopf, Matthew; Rona, Roberto J; Wessely, Simon

    2006-05-27

    UK armed forces personnel who took part in the 1991 Gulf war experienced an increase in symptomatic ill health, colloquially known as Gulf war syndrome. Speculation about an Iraq war syndrome has already started. We compared the health of male regular UK armed forces personnel deployed to Iraq during the 2003 war (n=3642) with that of their colleagues who were not deployed (n=4295), and compared these findings with those from our previous survey after the 1991 war. Data were obtained by questionnaire. Graphs comparing frequencies of 50 non-specific symptoms in the past month in deployed and non-deployed groups did not show an increase in prevalence of symptoms equivalent to that observed after the Gulf war. For the Iraq war survey, odds ratios (ORs) for self-reported symptoms ranged from 0.8 to 1.3. Five symptoms were significantly increased, and two decreased, in deployed individuals, whereas prevalence greatly increased for all symptoms in the Gulf war study (ORs 1.9-3.9). Fatigue was not increased after the 2003 Iraq war (OR 1.08; 95% CI 0.98-1.19) but was greatly increased after the 1991 Gulf war (3.39; 3.00-3.83). Personnel deployed to the Gulf war were more likely (2.00, 1.70-2.35) than those not deployed to report their health as fair or poor; no such effect was found for the Iraq war (0.94, 0.82-1.09). Increases in common symptoms in the 2003 Iraq war group were slight, and no pattern suggestive of a new syndrome was present. We consider several explanations for these differences.

  14. Own and parental war experience as a risk factor for mental health problems among adolescents with an immigrant background: results from a cross sectional study in Oslo, Norway

    PubMed Central

    2006-01-01

    Background An increasing proportion of immigrants to Western countries in the past decade are from war affected countries. The aim of this study was to estimate the prevalence of war experience among adolescents and their parents and to investigate possible differences in internalizing and externalizing mental health problems between adolescents exposed and unexposed to own and parental war experience. Method The study is based on a cross-sectional population-based survey of all 10th grade pupils in Oslo for two consecutive years. A total of 1,758 aadolescents were included, all with both parents born outside of Norway. Internalizing and externalizing mental health problems were measured by Hopkins Symptom Checklist-10 and subscales of the Strengths and Difficulties Questionnaire, respectively. Own and parental war experience is based on adolescent self-report. Results The proportion of adolescents with own war experience was 14% with the highest prevalence in immigrants from Eastern Europe and Sub-Saharan Africa. The proportion of parental war experience was 33% with Sub-Saharan Africa being highest. Adolescents reporting own war experience had higher scores for both internalizing and externalizing mental health problems compared to immigrants without war experience, but only externalizing problems reached statistically significant differences. For parental war experience there was a statistically significant relationship between parental war experience and internalizing mental health problems. The association remained significant after adjustment for parental educational level and adolescents' own war experience. Conclusion War exposure is highly prevalent among immigrants living in Oslo, Norway, both among adolescents themselves and their parents. Among immigrants to Norway, parental war experience appears to be stronger associated with mental health problems than adolescents own exposure to war experience. PMID:17081315

  15. Synthesis and Characterisation of Biocompatible Polymer-Conjugated Magnetic Beads for Enhancement Stability of Urease.

    PubMed

    Doğaç, Yasemin Ispirli; Teke, Mustafa

    2016-04-01

    We reported natural polymer-conjugated magnetic featured urease systems for removal of urea effectively. The optimum temperature (20-60 °C), optimum pH (3.0-10.0), kinetic parameters, thermal stability (4-70 °C), pH stability (4.0-9.0), operational stability (0-250 min), reusability (18 times) and storage stability (24 weeks) were studied for characterisation of the urease-encapsulated biocompatible polymer-conjugated magnetic beads. Also, the surface groups and chemical structure of the magnetic beads were determined by using attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR). The all urease-encapsulated magnetic beads protected their stability of 30-45 % relative activity at 70 °C. A significant increase was observed at their pH stability compared with the free urease for both acidic and alkaline medium. Besides this, their repeatability activity were approximately 100 % during 4(th) run. They showed residual activity of 50 % after 16 weeks. The importance of this work is enhancement stability of immobilised urease by biocompatible polymer-conjugated magnetic beads for the industrial application based on removal of urea.

  16. Fuels and Lubrication Researcher at the Aircraft Engine Research Laboratory

    NASA Image and Video Library

    1943-08-21

    A researcher at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory studies the fuel ignition process. Improved fuels and lubrication was an area of particular emphasis at the laboratory during World War II. The military sought to use existing types of piston engines in order to get large numbers of aircraft into the air as quickly as possible. To accomplish its goals, however, the military needed to increase the performance of these engines without having to wait for new models or extensive redesigns. The Aircraft Engine Research Laboratory was called on to lead this effort. The use of superchargers successfully enhanced engine performance, but the resulting heat increased engine knock [fuel detonation] and structural wear. These effects could be offset with improved cooling, lubrication, and fuel mixtures. The NACA researchers in the Fuels and Lubrication Division concentrated on new synthetic fuels, higher octane fuels, and fuel-injection systems. The laboratory studied 16 different types of fuel blends during the war, including extensive investigations of triptane and xylidine.

  17. Developing information-space Confidence Building Measures (CBMs) between India and Pakistan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yamin, Tughral

    The Internet has changed the world in ways hitherto unknown. The international financial system, air, land and maritime transport systems are all digitally linked. Similarly most militaries are fully or partially networked. This has not only sped up the decision making processes at all levels, it has also rendered these systems vulnerable to cyber-attacks. Cyber-warfare is now recognized as the most potent form of non-kinetic war fighting. In order to prevent large scale network-attacks, cyber-powers are simultaneously spending a lot of time, money and effort to erect redundant cyber-defenses and enhancing their offensive cyber capabilities. Difficulties in creating a stablemore » environment in information-space stem from differing national perceptions regarding the freedom of the Internet, application of international law and problems associated with attribution. This paper discusses a range of Confidence Building Measures that can be created between India and Pakistan in information-space to control malicious cyber behavior and avert an inadvertent war.« less

  18. The influence of mindfulness, self-compassion, psychological flexibility, and posttraumatic stress disorder on disability and quality of life over time in war veterans.

    PubMed

    Meyer, Eric C; Frankfurt, Sheila B; Kimbrel, Nathan A; DeBeer, Bryann B; Gulliver, Suzy B; Morrisette, Sandra B

    2018-07-01

    Posttraumatic stress disorder (PTSD) strongly predicts greater disability and lower quality of life (QOL). Mindfulness-based and other third-wave behavior therapy interventions improve well-being by enhancing mindfulness, self-compassion, and psychological flexibility. We hypothesized that these mechanisms of therapeutic change would comprise a single latent factor that would predict disability and QOL after accounting for PTSD symptom severity. Iraq and Afghanistan war veterans (N = 117) completed a study of predictors of successful reintegration. Principal axis factor analysis tested whether mindfulness, self-compassion, and psychological flexibility comprised a single latent factor. Hierarchical regression tested whether this factor predicted disability and QOL 1 year later. Mindfulness, self-compassion, and psychological flexibility comprised a single factor that predicted disability and QOL after accounting for PTSD symptom severity. PTSD symptoms remained a significant predictor of disability but not QOL. Targeting these mechanisms may help veterans achieve functional recovery, even in the presence of PTSD symptoms. © 2018 Wiley Periodicals, Inc.

  19. Surgical and Resuscitation Capabilities for the "Next War" Based on Lessons Learned From "This War".

    PubMed

    Freel, David; Warr, Bradley J

    2016-01-01

    The Army gleaned many lessons regarding the provision of medical care to casualties during the past 14 years of combat. Using these lessons learned in the Joint Capabilities and Integration Development process and through the analysis of an integrated process action team, the Army recently approved 3 changes to medical organizations that are intended to provide trauma management farther forward on the battlefield. These changes include the substitution of an emergency medicine trained physician and emergency medicine physician assistant (PA) in lieu of a general medical officer and primary care PA within the brigade combat team; reorganization of the forward surgical team into a forward surgical and resuscitative team; and the modularization of the traditional 248 bed combat support hospital. The Army anticipates that these changes related to personnel, organizations, doctrine, and materiel will enable Army medicine to provide enhanced trauma management closer to the point of a combatant's injury. These modifications are projected to begin in fiscal year 2016.

  20. Counterproliferation strategy: The influence of technology, budget, and arms control on theater missile defenses. Strategic research project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parlier, G.H.

    1996-05-20

    This paper describes the historical evolution of the theater missile threat during World War II and the Persian Gulf War, and analyzes current technological challenges, budgetary pressures, and arms control restraints which constrain the development and deployment of effective theater missile defenses. The impact of these trends on strategic concepts as outlined in the National Military Strategy and their implications for attaining national policy objectives is assessed. A systems approach is used to described analyze, and evaluate the effectiveness of emerging counterproliferation strategy within the framework of an ends-ways-means strategy formulation paradigm. I conclude that current trends will lead tomore » a self-deterring strategy: resources are inadequate to support the ways we intend to achieve our national objectives. Recommendations are made to eliminate unacceptable risk and enhance the concept of `extended conventional deterrence` consistent with U.S. national values and security interests for our role in a new world order.« less

  1. Positive Adjustment Among American Repatriated Prisoners of the Vietnam War: Modeling the Long-Term Effects of Captivity.

    PubMed

    King, Daniel W; King, Lynda A; Park, Crystal L; Lee, Lewina O; Kaiser, Anica Pless; Spiro, Avron; Moore, Jeffrey L; Kaloupek, Danny G; Keane, Terence M

    2015-11-01

    A longitudinal lifespan model of factors contributing to later-life positive adjustment was tested on 567 American repatriated prisoners from the Vietnam War. This model encompassed demographics at time of capture and attributes assessed after return to the U.S. (reports of torture and mental distress) and approximately 3 decades later (later-life stressors, perceived social support, positive appraisal of military experiences, and positive adjustment). Age and education at time of capture and physical torture were associated with repatriation mental distress, which directly predicted poorer adjustment 30 years later. Physical torture also had a salutary effect, enhancing later-life positive appraisals of military experiences. Later-life events were directly and indirectly (through concerns about retirement) associated with positive adjustment. Results suggest that the personal resources of older age and more education and early-life adverse experiences can have cascading effects over the lifespan to impact well-being in both positive and negative ways.

  2. Positive Adjustment Among American Repatriated Prisoners of the Vietnam War: Modeling the Long-Term Effects of Captivity

    PubMed Central

    King, Daniel W.; King, Lynda A.; Park, Crystal L.; Lee, Lewina O.; Kaiser, Anica Pless; Spiro, Avron; Moore, Jeffrey L.; Kaloupek, Danny G.; Keane, Terence M.

    2015-01-01

    A longitudinal lifespan model of factors contributing to later-life positive adjustment was tested on 567 American repatriated prisoners from the Vietnam War. This model encompassed demographics at time of capture and attributes assessed after return to the U.S. (reports of torture and mental distress) and approximately 3 decades later (later-life stressors, perceived social support, positive appraisal of military experiences, and positive adjustment). Age and education at time of capture and physical torture were associated with repatriation mental distress, which directly predicted poorer adjustment 30 years later. Physical torture also had a salutary effect, enhancing later-life positive appraisals of military experiences. Later-life events were directly and indirectly (through concerns about retirement) associated with positive adjustment. Results suggest that the personal resources of older age and more education and early-life adverse experiences can have cascading effects over the lifespan to impact well-being in both positive and negative ways. PMID:26693100

  3. Think tank (2) Its development and the current situation of the key organizations in Japan

    NASA Astrophysics Data System (ADS)

    Obara, Michio

    There were some think tank businesses in Japan before the war. South Manchuria Railway Company established its Research Department for the purpose of getting power to control Manchuria as a colony, and got the good results. Think tank business was flourishing three times after the war. This business attracts much attention when the social and economic paradigm is going to change. Among the key large-scale think tanks in Japan, Nomura Research Institute, Ltd. (NRI) was the first to enhance the system functions by the merger, and posted think tank function up in the SI business. Mitsubishi Research Institute, Inc. (MRI) intends to be an orthodox think tank, and established an advanced research institute and the laboratory for R&D. Daiwa Institute of Research, Ltd. (DIR) focuses on economic forecast by using system. Fuji Research Institute. Corp. (FUJI RIC) focuses on survey and policy proposing in macro-economics, and analyzing technology. The Japan Research Institute, Ltd. (JRI) focuses on regional development, and R&D in advanced technology.

  4. Think tank (3) - Present activities of other representative organizations

    NASA Astrophysics Data System (ADS)

    Obara, Michio

    There were some think tank businesses in Japan before the war. South Manchuria Railway Company established its Research Department for the purpose of getting power to control Manchuria as a colony, and got the good results. Think tank business was flourishing three times after the war. This business attracts much attention when the social and economic paradigm is going to change. Among the key large-scale think tanks in Japan, Nomura Research Institute, Ltd. (NRI) was the first to enhance the system functions by the merger, and posted think tank function up in the SI business. Mitsubishi Research Institute, Inc. (MRI) intends to be an orthodox think tank, and established an advanced research institute and the laboratory for R&D. Daiwa Institute of Research, Ltd. (DIR) focuses on economic forecast by using system. Fuji Research Institute, Corp. (FUJI RIC) focuses on survey and policy proposing in macro-economics, and analyzing technology. The Japan Research Institute, Ltd. (JRI) focuses on regional development, and R&D in advanced technology.

  5. VMCast: A VM-Assisted Stability Enhancing Solution for Tree-Based Overlay Multicast

    PubMed Central

    Gu, Weidong; Zhang, Xinchang; Gong, Bin; Zhang, Wei; Wang, Lu

    2015-01-01

    Tree-based overlay multicast is an effective group communication method for media streaming applications. However, a group member’s departure causes all of its descendants to be disconnected from the multicast tree for some time, which results in poor performance. The above problem is difficult to be addressed because overlay multicast tree is intrinsically instable. In this paper, we proposed a novel stability enhancing solution, VMCast, for tree-based overlay multicast. This solution uses two types of on-demand cloud virtual machines (VMs), i.e., multicast VMs (MVMs) and compensation VMs (CVMs). MVMs are used to disseminate the multicast data, whereas CVMs are used to offer streaming compensation. The used VMs in the same cloud datacenter constitute a VM cluster. Each VM cluster is responsible for a service domain (VMSD), and each group member belongs to a specific VMSD. The data source delivers the multicast data to MVMs through a reliable path, and MVMs further disseminate the data to group members along domain overlay multicast trees. The above approach structurally improves the stability of the overlay multicast tree. We further utilized CVM-based streaming compensation to enhance the stability of the data distribution in the VMSDs. VMCast can be used as an extension to existing tree-based overlay multicast solutions, to provide better services for media streaming applications. We applied VMCast to two application instances (i.e., HMTP and HCcast). The results show that it can obviously enhance the stability of the data distribution. PMID:26562152

  6. VMCast: A VM-Assisted Stability Enhancing Solution for Tree-Based Overlay Multicast.

    PubMed

    Gu, Weidong; Zhang, Xinchang; Gong, Bin; Zhang, Wei; Wang, Lu

    2015-01-01

    Tree-based overlay multicast is an effective group communication method for media streaming applications. However, a group member's departure causes all of its descendants to be disconnected from the multicast tree for some time, which results in poor performance. The above problem is difficult to be addressed because overlay multicast tree is intrinsically instable. In this paper, we proposed a novel stability enhancing solution, VMCast, for tree-based overlay multicast. This solution uses two types of on-demand cloud virtual machines (VMs), i.e., multicast VMs (MVMs) and compensation VMs (CVMs). MVMs are used to disseminate the multicast data, whereas CVMs are used to offer streaming compensation. The used VMs in the same cloud datacenter constitute a VM cluster. Each VM cluster is responsible for a service domain (VMSD), and each group member belongs to a specific VMSD. The data source delivers the multicast data to MVMs through a reliable path, and MVMs further disseminate the data to group members along domain overlay multicast trees. The above approach structurally improves the stability of the overlay multicast tree. We further utilized CVM-based streaming compensation to enhance the stability of the data distribution in the VMSDs. VMCast can be used as an extension to existing tree-based overlay multicast solutions, to provide better services for media streaming applications. We applied VMCast to two application instances (i.e., HMTP and HCcast). The results show that it can obviously enhance the stability of the data distribution.

  7. The First World War and Its Implications for Education in British Museums.

    ERIC Educational Resources Information Center

    Kavanagh, Gaynor

    1988-01-01

    Examines how the First World War prompted British museums to change their educational functions. Discusses museums in pre-war Britain, wartime exhibitions and educational activities, the outcome of the war experience, and First World War's implications for education in museums. (GEA)

  8. 46 CFR 308.540 - Premiums.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Facultative War Risk Cargo Insurance § 308.540 Premiums. (a) Rates. Rate Schedules for war risk facultative... without notice. If no rate is published for a voyage on which war risk facultative cargo insurance is...

  9. The Civil War on the Internet: A Selection of the Best Web Sources for Educators and Students

    ERIC Educational Resources Information Center

    Dyson, Rick

    2004-01-01

    The American Civil War, the War between the States, War of the Rebellion, the Second American Revolution, and the War of Southern Independence are all names for the bloodiest conflict in American history. That war of many names has inspired authors to write thousands of books and articles. With the advent of the Internet came a plethora of Web…

  10. Whose History? An Analysis of the Korean War in History Textbooks from the United States, South Korea, Japan, and China

    ERIC Educational Resources Information Center

    Lin, Lin; Zhao, Yali; Ogawa, Masato; Hoge, John; Kim, Bok Young

    2009-01-01

    This article examines how recent history textbooks from the United States, Japan, China, and South Korea present the Korean War. The comparative analysis focuses on four areas: the causes of the Korean War, American involvement in the war, Chinese involvement in the war, and the results of the war. Analysis of the central story lines reveals that…

  11. 20 CFR 404.1363 - Treatment of social security benefits or payments where Federal benefit payable other than by...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-sum death payment based on World War II or post-World War II wage credits after we receive notice from... War II or post-World War II active service, our payments to you are erroneous to the extent the payments are based on the World War II or post-World War II wage credits. The payments are erroneous...

  12. 20 CFR 404.1363 - Treatment of social security benefits or payments where Federal benefit payable other than by...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...-sum death payment based on World War II or post-World War II wage credits after we receive notice from... War II or post-World War II active service, our payments to you are erroneous to the extent the payments are based on the World War II or post-World War II wage credits. The payments are erroneous...

  13. Impacts on Chinese Agriculture of Geoengineering and Smoke from Fires Ignited by Nuclear War

    NASA Astrophysics Data System (ADS)

    Xia, L.; Robock, A.

    2013-12-01

    Climate is one of the most important factors determining crop yields and world food supplies. To be well prepared for possible futures, it is necessary to study yield changes of major crops under different climate scenarios. Here we consider two situations: stratospheric sulfate geoengineering and nuclear war. Although we certainly do not advocate either scenario, we cannot exclude the possibilities: if global warming is getting worse, society might consider deliberately manipulating global temperature; if nuclear weapons still exist, we might face a nuclear war catastrophe. Since in both scenarios there would be reductions of temperature, precipitation, and insolation, which are three controlling factors on crop growth, it is important to study food supply changes under the two cases. We conducted our simulations for China, because it has the highest population and crop production in the world and it is under the strong influence of the summer monsoon, which would be altered in geoengineering and nuclear war scenarios. To examine the effects of climate changes induced by geoengineering and nuclear war on Chinese agriculture, we use the Decision Support System for Agrotechnology Transfer (DSSAT) crop model. We first evaluated the model by forcing it with daily weather data and management practices for the period 1978-2008 for 24 provinces in China, and compared the results to observations of the yields of major crops in China (middle season rice, winter wheat, and maize). Then we perturbed observed weather data using climate anomalies for geoengineering and nuclear war simulations. For geoengineering, we consider the G2 scenario of the Geoengineering Model Intercomparison Project (GeoMIP), which prescribes an insolation reduction to balance a 1% per year increase in CO2 concentration (1pctCO2). We used results from ten climate models participating in G2. For the nuclear war scenario, we consider the effects of 5 Tg of soot that could be injected into the upper troposphere by a war between India and Pakistan using only 100 Hiroshima-size atomic bombs dropped on cities. We used results from three climate models that did the same simulation. For the geoengineering scenario, without changes of agricultural technology, the combined effect of climate changes due to geoengineering and CO2 fertilization would change rice production in China by -4.6×6.0 Mt (4.5×5.9%) as compared with 1pctCO2 and would increase Chinese maize production by 20.9×6.9 Mt (14.8×4.9%) the period 46-50 years after the CO2 increase and compensating insolation reduction began. The CO2 fertilization effect compensates for the deleterious impacts of climate changes due to geoengineering on rice production, increasing rice production by 8.2 Mt and the elevated CO2 concentration enhances maize production in G2, contributing 35.5% to the total increase. While agricultural impacts may not be a serious problem for geoengineering, there are many other potential risks that need to be evaluated before geoengineering should be considered. Climate changes due to nuclear war would decrease Chinese rice production by 20×4.7%, maize production by 15×6.2% and winter wheat production by 35×19.3% for a five-year period after the soot injection, producing a major world food security crisis.

  14. [The prevalence of war-related post-traumatic stress disorder in children from Cundinamarca, Colombia].

    PubMed

    Pérez-Olmos, Isabel; Fernández-Piñeres, Patricia E; Rodado-Fuentes, Sonia

    2005-01-01

    Determining the prevalence of post-traumatic stress disorder (PTSD) related to the type of war exposure and associated factors in school-aged children from three Colombian towns. Cross-sectional epidemiological study. Representative randomised sample of 493 children aged 5-14. The children were evaluated during 2002 using semi-structured psychiatric interviews and the clinician administered PTSD scale. 167 children were evaluated in La Palma who had been chronically exposed to war, 164 in Arbeláez who had had recent war-exposure and 162 in Sopó who had not been exposed to war. War-related PTSD prevalence was calculated in each municipality. Odds ratio (OR) and chi-square were used for evaluating the association between exposure to war and PTSD and the related risk. Multivariate analysis used the logistic regression model. The affected children required specialised mental health counselling. The prevalence of PTSD resulting from war was 16,8 % in La Palma, 23,2 % in Arbeláez and 1.2% in Sopó. A 19.9 OR (CI 4.7, 119.2), 30,5 Chi-square and p = 0.000 revealed war-related PTSD association and risk for children when comparing the exposed towns to Sopó. The logistic regression showed that geographical closeness to war zone and intense emotional reaction to war increased the probability of war-related PTSD. Vulnerability factors were predominant in war-exposed towns. Poverty, parents' low educational level and child abuse predominated in La Palma. Attention-deficit and psychosomatic disorders were more prevalent in Arbeláez. War affects children's mental health; the children from the exposed towns had 19 times greater probability of war-related PTSD than those from a non-exposed town. Early therapeutic intervention is a public health priority. The results are useful for countries suffering from war, internal conflict and/or terrorism.

  15. 46 CFR 308.544 - Facultative binder, Form MA-315.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.544 Facultative binder, Form MA-315. The standard form of War Risk Facultative Cargo Binder, which may be obtained from the American War...

  16. 46 CFR 308.544 - Facultative binder, Form MA-315.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.544 Facultative binder, Form MA-315. The standard form of War Risk Facultative Cargo Binder, which may be obtained from the American War...

  17. 46 CFR 308.540 - Premiums.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.540 Premiums. (a) Rates. Rate Schedules for war risk facultative... without notice. If no rate is published for a voyage on which war risk facultative cargo insurance is...

  18. 46 CFR 308.540 - Premiums.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.540 Premiums. (a) Rates. Rate Schedules for war risk facultative... without notice. If no rate is published for a voyage on which war risk facultative cargo insurance is...

  19. 46 CFR 308.104 - Additional war risk insurance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false Additional war risk insurance. 308.104 Section 308.104 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Hull and Disbursements Insurance § 308.104 Additional war risk insurance. Owners or charterers may...

  20. 46 CFR 308.104 - Additional war risk insurance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Additional war risk insurance. 308.104 Section 308.104 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Hull and Disbursements Insurance § 308.104 Additional war risk insurance. Owners or charterers may...

  1. 46 CFR 308.540 - Premiums.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.540 Premiums. (a) Rates. Rate Schedules for war risk facultative... without notice. If no rate is published for a voyage on which war risk facultative cargo insurance is...

  2. 46 CFR 308.544 - Facultative binder, Form MA-315.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.544 Facultative binder, Form MA-315. The standard form of War Risk Facultative Cargo Binder, which may be obtained from the American War...

  3. 46 CFR 308.104 - Additional war risk insurance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Additional war risk insurance. 308.104 Section 308.104 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Hull and Disbursements Insurance § 308.104 Additional war risk insurance. Owners or charterers may...

  4. 46 CFR 308.544 - Facultative binder, Form MA-315.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.544 Facultative binder, Form MA-315. The standard form of War Risk Facultative Cargo Binder, which may be obtained from the American War...

  5. 46 CFR 308.104 - Additional war risk insurance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Additional war risk insurance. 308.104 Section 308.104 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Hull and Disbursements Insurance § 308.104 Additional war risk insurance. Owners or charterers may...

  6. 46 CFR 308.540 - Premiums.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.540 Premiums. (a) Rates. Rate Schedules for war risk facultative... without notice. If no rate is published for a voyage on which war risk facultative cargo insurance is...

  7. 46 CFR 308.104 - Additional war risk insurance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false Additional war risk insurance. 308.104 Section 308.104 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Hull and Disbursements Insurance § 308.104 Additional war risk insurance. Owners or charterers may...

  8. Effects of ionic strength and sugars on the aggregation propensity of monoclonal antibodies: influence of colloidal and conformational stabilities.

    PubMed

    Saito, Shuntaro; Hasegawa, Jun; Kobayashi, Naoki; Tomitsuka, Toshiaki; Uchiyama, Susumu; Fukui, Kiichi

    2013-05-01

    To develop a general strategy for optimizing monoclonal antibody (MAb) formulations. Colloidal stabilities of four representative MAbs solutions were assessed based on the second virial coefficient (B 2) at 20°C and 40°C, and net charges at different NaCl concentrations, and/or in the presence of sugars. Conformational stabilities were evaluated from the unfolding temperatures. The aggregation propensities were determined at 40°C and after freeze-thawing. The electrostatic potential of antibody surfaces was simulated for the development of rational formulations. Similar B 2 values were obtained at 20°C and 40°C, implying little dependence on temperature. B 2 correlated quantitatively with aggregation propensities at 40°C. The net charge partly correlated with colloidal stability. Salts stabilized or destabilized MAbs, depending on repulsive or attractive interactions. Sugars improved the aggregation propensity under freeze-thaw stress through improved conformational stability. Uneven and even distributions of potential surfaces were attributed to attractive and strong repulsive electrostatic interactions. Assessment of colloidal stability at the lowest ionic strength is particularly effective for the development of formulations. If necessary, salts are added to enhance the colloidal stability. Sugars further improved aggregation propensities by enhancing conformational stability. These behaviors are rationally predictable according to the surface potentials of MAbs.

  9. Efficient affinity maturation of antibody variable domains requires co-selection of compensatory mutations to maintain thermodynamic stability

    PubMed Central

    Julian, Mark C.; Li, Lijuan; Garde, Shekhar; Wilen, Rebecca; Tessier, Peter M.

    2017-01-01

    The ability of antibodies to accumulate affinity-enhancing mutations in their complementarity-determining regions (CDRs) without compromising thermodynamic stability is critical to their natural function. However, it is unclear if affinity mutations in the hypervariable CDRs generally impact antibody stability and to what extent additional compensatory mutations are required to maintain stability during affinity maturation. Here we have experimentally and computationally evaluated the functional contributions of mutations acquired by a human variable (VH) domain that was evolved using strong selections for enhanced stability and affinity for the Alzheimer’s Aβ42 peptide. Interestingly, half of the key affinity mutations in the CDRs were destabilizing. Moreover, the destabilizing effects of these mutations were compensated for by a subset of the affinity mutations that were also stabilizing. Our findings demonstrate that the accumulation of both affinity and stability mutations is necessary to maintain thermodynamic stability during extensive mutagenesis and affinity maturation in vitro, which is similar to findings for natural antibodies that are subjected to somatic hypermutation in vivo. These findings for diverse antibodies and antibody fragments specific for unrelated antigens suggest that the formation of the antigen-binding site is generally a destabilizing process and that co-enrichment for compensatory mutations is critical for maintaining thermodynamic stability. PMID:28349921

  10. Long-term rice cultivation stabilizes soil organic carbon and promotes soil microbial activity in a salt marsh derived soil chronosequence

    PubMed Central

    Wang, Ping; Liu, Yalong; Li, Lianqing; Cheng, Kun; Zheng, Jufeng; Zhang, Xuhui; Zheng, Jinwei; Joseph, Stephen; Pan, Genxing

    2015-01-01

    Soil organic carbon (SOC) sequestration with enhanced stable carbon storage has been widely accepted as a very important ecosystem property. Yet, the link between carbon stability and bio-activity for ecosystem functioning with OC accumulation in field soils has not been characterized. We assessed the changes in microbial activity versus carbon stability along a paddy soil chronosequence shifting from salt marsh in East China. We used mean weight diameter, normalized enzyme activity (NEA) and carbon gain from straw amendment for addressing soil aggregation, microbial biochemical activity and potential C sequestration, respectively. In addition, a response ratio was employed to infer the changes in all analyzed parameters with prolonged rice cultivation. While stable carbon pools varied with total SOC accumulation, soil respiration and both bacterial and fungal diversity were relatively constant in the rice soils. Bacterial abundance and NEA were positively but highly correlated to total SOC accumulation, indicating an enhanced bio-activity with carbon stabilization. This could be linked to an enhancement of particulate organic carbon pool due to physical protection with enhanced soil aggregation in the rice soils under long-term rice cultivation. However, the mechanism underpinning these changes should be explored in future studies in rice soils where dynamic redox conditions exist. PMID:26503629

  11. Long-term rice cultivation stabilizes soil organic carbon and promotes soil microbial activity in a salt marsh derived soil chronosequence

    NASA Astrophysics Data System (ADS)

    Wang, Ping; Liu, Yalong; Li, Lianqing; Cheng, Kun; Zheng, Jufeng; Zhang, Xuhui; Zheng, Jinwei; Joseph, Stephen; Pan, Genxing

    2015-10-01

    Soil organic carbon (SOC) sequestration with enhanced stable carbon storage has been widely accepted as a very important ecosystem property. Yet, the link between carbon stability and bio-activity for ecosystem functioning with OC accumulation in field soils has not been characterized. We assessed the changes in microbial activity versus carbon stability along a paddy soil chronosequence shifting from salt marsh in East China. We used mean weight diameter, normalized enzyme activity (NEA) and carbon gain from straw amendment for addressing soil aggregation, microbial biochemical activity and potential C sequestration, respectively. In addition, a response ratio was employed to infer the changes in all analyzed parameters with prolonged rice cultivation. While stable carbon pools varied with total SOC accumulation, soil respiration and both bacterial and fungal diversity were relatively constant in the rice soils. Bacterial abundance and NEA were positively but highly correlated to total SOC accumulation, indicating an enhanced bio-activity with carbon stabilization. This could be linked to an enhancement of particulate organic carbon pool due to physical protection with enhanced soil aggregation in the rice soils under long-term rice cultivation. However, the mechanism underpinning these changes should be explored in future studies in rice soils where dynamic redox conditions exist.

  12. Long-term rice cultivation stabilizes soil organic carbon and promotes soil microbial activity in a salt marsh derived soil chronosequence.

    PubMed

    Wang, Ping; Liu, Yalong; Li, Lianqing; Cheng, Kun; Zheng, Jufeng; Zhang, Xuhui; Zheng, Jinwei; Joseph, Stephen; Pan, Genxing

    2015-10-27

    Soil organic carbon (SOC) sequestration with enhanced stable carbon storage has been widely accepted as a very important ecosystem property. Yet, the link between carbon stability and bio-activity for ecosystem functioning with OC accumulation in field soils has not been characterized. We assessed the changes in microbial activity versus carbon stability along a paddy soil chronosequence shifting from salt marsh in East China. We used mean weight diameter, normalized enzyme activity (NEA) and carbon gain from straw amendment for addressing soil aggregation, microbial biochemical activity and potential C sequestration, respectively. In addition, a response ratio was employed to infer the changes in all analyzed parameters with prolonged rice cultivation. While stable carbon pools varied with total SOC accumulation, soil respiration and both bacterial and fungal diversity were relatively constant in the rice soils. Bacterial abundance and NEA were positively but highly correlated to total SOC accumulation, indicating an enhanced bio-activity with carbon stabilization. This could be linked to an enhancement of particulate organic carbon pool due to physical protection with enhanced soil aggregation in the rice soils under long-term rice cultivation. However, the mechanism underpinning these changes should be explored in future studies in rice soils where dynamic redox conditions exist.

  13. Breaking New Ground on War and Peace.

    ERIC Educational Resources Information Center

    Bock, Paul

    1983-01-01

    The American Catholic Church, which has historically supported America's involvement in wars through the concept of just wars, has broken new ground with its Pastoral Letter on War, Armaments, and Peace, which challenges the morality of present defense policy and nuclear war. Reasons for the change in attitude are discussed. (IS)

  14. 20 CFR 404.1301 - Introduction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., through December 31, 1956. These individuals are considered World War II or post-World War II veterans... military or naval service of an allied country during World War II. These individuals are considered World.... These individuals are considered members of the uniformed services. (b) World War II or post-World War...

  15. 20 CFR 404.1301 - Introduction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., through December 31, 1956. These individuals are considered World War II or post-World War II veterans... military or naval service of an allied country during World War II. These individuals are considered World.... These individuals are considered members of the uniformed services. (b) World War II or post-World War...

  16. 20 CFR 404.1301 - Introduction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., through December 31, 1956. These individuals are considered World War II or post-World War II veterans... military or naval service of an allied country during World War II. These individuals are considered World.... These individuals are considered members of the uniformed services. (b) World War II or post-World War...

  17. American Women and the Great War.

    ERIC Educational Resources Information Center

    Dumenil, Lynn

    2002-01-01

    Provides information on the idealized images of women during World War I. Features the use of posters and propaganda during the war. Focuses on voluntary activities in which women participated, the fight for women's suffrage during the war, and the effect of the war on women working. Includes poster reproductions. (CMK)

  18. The Implications of Preemptive and Preventive War Doctrines: A Reconsideration

    DTIC Science & Technology

    2007-07-01

    geopolitics, ideology , and personality as combining to produce the fatal brew which resulted in 42 years of nuclear shadowed global menace.26 But...preventive war. 49 1. Preventive war is war, and preventive warfare is warfare. It is not a distinctive genus of war and warfare. The distinguishing

  19. 37 CFR 5.18 - Arms, ammunition, and implements of war.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... implements of war. 5.18 Section 5.18 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK... implements of war. (a) The exportation of technical data relating to arms, ammunition, and implements of war... parts 120 through 130); the articles designated as arms, ammunitions, and implements of war are...

  20. War and Children's Mortality.

    ERIC Educational Resources Information Center

    Carlton-Ford, Steve; Houston, Paula; Hamill, Ann

    2000-01-01

    Examines impact of war on young children's mortality in 137 countries. Finds that years recently at war (1990-5) interact with years previously at war (1946-89) to elevate mortality rates. Religious composition interacts with years recently at war to reduce effect. Controlling for women's literacy and access to safe water eliminates effect for…

  1. 46 CFR 308.107 - War risk hull insurance policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false War risk hull insurance policy. 308.107 Section 308.107 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Hull and Disbursements Insurance § 308.107 War risk hull insurance policy. Standard Form MA-240...

  2. Vietnam: Historians at War

    ERIC Educational Resources Information Center

    Moyar, Mark

    2008-01-01

    Although the Vietnam War ended more than thirty years ago, historians remain as divided on what happened as the American people were during the war. Mark Moyar maps the ongoing battle between "orthodox" and "revisionist" Vietnam War historians: the first group, those who depict Vietnam as a bad war that the United States should…

  3. 46 CFR 308.204 - Additional war risk protection and indemnity insurance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false Additional war risk protection and indemnity insurance. 308.204 Section 308.204 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.204 Additional war risk...

  4. 46 CFR 308.204 - Additional war risk protection and indemnity insurance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Additional war risk protection and indemnity insurance. 308.204 Section 308.204 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.204 Additional war risk...

  5. 75 FR 57839 - National POW/MIA Recognition Day, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... prisoners of war in distant lands, and to all servicemembers who have defended American lives and liberties... bring them home. Each year, specialists in our Department of Defense scour foreign battlefields and... those missing from the Vietnam War, Korean War, Cold War, World War II, and other conflicts. Their work...

  6. 46 CFR 308.204 - Additional war risk protection and indemnity insurance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Additional war risk protection and indemnity insurance. 308.204 Section 308.204 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.204 Additional war risk...

  7. 46 CFR 308.107 - War risk hull insurance policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false War risk hull insurance policy. 308.107 Section 308.107 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Hull and Disbursements Insurance § 308.107 War risk hull insurance policy. Standard Form MA-240...

  8. 46 CFR 308.207 - War risk protection and indemnity insurance policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false War risk protection and indemnity insurance policy. 308.207 Section 308.207 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.207 War risk protection and...

  9. 46 CFR 308.207 - War risk protection and indemnity insurance policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false War risk protection and indemnity insurance policy. 308.207 Section 308.207 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.207 War risk protection and...

  10. 46 CFR 308.207 - War risk protection and indemnity insurance policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false War risk protection and indemnity insurance policy. 308.207 Section 308.207 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.207 War risk protection and...

  11. 46 CFR 308.207 - War risk protection and indemnity insurance policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false War risk protection and indemnity insurance policy. 308.207 Section 308.207 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.207 War risk protection and...

  12. 46 CFR 308.107 - War risk hull insurance policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false War risk hull insurance policy. 308.107 Section 308.107 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Hull and Disbursements Insurance § 308.107 War risk hull insurance policy. Standard Form MA-240...

  13. 46 CFR 308.207 - War risk protection and indemnity insurance policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false War risk protection and indemnity insurance policy. 308.207 Section 308.207 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.207 War risk protection and...

  14. 46 CFR 308.204 - Additional war risk protection and indemnity insurance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Additional war risk protection and indemnity insurance. 308.204 Section 308.204 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.204 Additional war risk...

  15. 46 CFR 308.107 - War risk hull insurance policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false War risk hull insurance policy. 308.107 Section 308.107 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Hull and Disbursements Insurance § 308.107 War risk hull insurance policy. Standard Form MA-240...

  16. 46 CFR 308.204 - Additional war risk protection and indemnity insurance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false Additional war risk protection and indemnity insurance. 308.204 Section 308.204 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Protection and Indemnity Insurance § 308.204 Additional war risk...

  17. 46 CFR 308.107 - War risk hull insurance policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false War risk hull insurance policy. 308.107 Section 308.107 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Hull and Disbursements Insurance § 308.107 War risk hull insurance policy. Standard Form MA-240...

  18. The stability of portfolio investment in stock crashes

    NASA Astrophysics Data System (ADS)

    Li, Yun-Xian; Qian, Zhen-Wei; Li, Jiang-Cheng; Tang, Nian-Sheng; Mei, Dong-Cheng

    2016-08-01

    The stability of portfolio investment in stock market crashes with Markowitz portfolio is investigated by the method of theoretical and empirical simulation. From numerical simulation of the mean escape time (MET), we conclude that: (i) The increasing number (Np) of stocks in Markowitz portfolio induces a maximum in the curve of MET versus the initial position; (ii) A critical value of Np in the behavior of MET versus the long-run variance or amplitude of volatility fluctuations maximumlly enhances the stability of portfolio investment. When Np takes value below the critical value, the increasing Np enhances the stability of portfolio investment, but restrains it when Np takes value above the critical value. In addition, a good agreement of both the MET and probability density functions of returns is found between real data and theoretical results.

  19. 20 CFR 404.1343 - When the limits on granting World War II and post-World War II wage credits do not apply.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false When the limits on granting World War II and post-World War II wage credits do not apply. 404.1343 Section 404.1343 Employees' Benefits SOCIAL... When the limits on granting World War II and post-World War II wage credits do not apply. The limits on...

  20. 20 CFR 404.1343 - When the limits on granting World War II and post-World War II wage credits do not apply.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false When the limits on granting World War II and post-World War II wage credits do not apply. 404.1343 Section 404.1343 Employees' Benefits SOCIAL... When the limits on granting World War II and post-World War II wage credits do not apply. The limits on...

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