JPRS Report, Science and Technology, China: Energy.

DTIC Science & Technology

1991-01-16

10 First Unit of Sichuan’s Longqiao Plant Now Operational [Wang Dingguo, Yang Qingwen; SICHUAN RIBAO, 8 Aug 90...Zhao Zhilin , et al.; SICHUAN RIBAO, 31 May 90] ..................................................... 23 Low Temperature Heat-Supply Reactor Opens New...and SICHUAN the first phase for the power plant. RIBAO reporter Yang Qingwen [2799 3237 2429]: "Fuling JPRS-CEN-91-001 12 THERMAL POWER 16 January

Integrated identification, qualification and quantification strategy for pharmacokinetic profile study of Guizhi Fuling capsule in healthy volunteers

PubMed Central

Zhong, Yun-Xi; Jin, Xiao-Liang; Gu, Shi-Yin; Peng, Ying; Zhang, Ke-Rong; Ou-Yang, Bing-Chen; Wang, Yu; Xiao, Wei; Wang, Zhen-Zhong; Aa, Ji-Ye; Wang, Guang-Ji; Sun, Jian-Guo

2016-01-01

Guizhi Fuling capsule (GZFL), a traditional Chinese medicine formulation, is widely used in China to relieve pain from dysmenorrhea and is now in a Phase II clinical trial in the USA. Due to the low exposure of the five main medicative ingredients (amygdalin, cinnamic acid, gallic acid, paeoniflorin and paeonol) of GZFL in human, a strategy was built to qualitatively and quantitatively identify the possible metabolites of GZFL and to describe the pharmacokinetic profiles of GZFL in human. In this strategy, LC-Q-TOF/MS was used to identify and structurally elucidate the possible metabolites of GZFL in vivo; and a time-based metabolite-confirming step (TBMCs) was used to confirm uncertain metabolites. The simultaneously quantitation results by LC-MS/MS showed low exposure of the five medicative ingredients. According to the strategy we built, a total of 36 metabolites were found and structurally elucidated. The simultaneously semi-quantitative analysis by LC-MS/MS showed that obvious time-concentration curves could be established for 12 of the metabolites, and most of them showed a relatively higher exposure. This study provides a better understanding of the metabolic processes of GZFL in human. PMID:27527657

Integrated identification, qualification and quantification strategy for pharmacokinetic profile study of Guizhi Fuling capsule in healthy volunteers.

PubMed

Zhong, Yun-Xi; Jin, Xiao-Liang; Gu, Shi-Yin; Peng, Ying; Zhang, Ke-Rong; Ou-Yang, Bing-Chen; Wang, Yu; Xiao, Wei; Wang, Zhen-Zhong; Aa, Ji-Ye; Wang, Guang-Ji; Sun, Jian-Guo

2016-08-16

Guizhi Fuling capsule (GZFL), a traditional Chinese medicine formulation, is widely used in China to relieve pain from dysmenorrhea and is now in a Phase II clinical trial in the USA. Due to the low exposure of the five main medicative ingredients (amygdalin, cinnamic acid, gallic acid, paeoniflorin and paeonol) of GZFL in human, a strategy was built to qualitatively and quantitatively identify the possible metabolites of GZFL and to describe the pharmacokinetic profiles of GZFL in human. In this strategy, LC-Q-TOF/MS was used to identify and structurally elucidate the possible metabolites of GZFL in vivo; and a time-based metabolite-confirming step (TBMCs) was used to confirm uncertain metabolites. The simultaneously quantitation results by LC-MS/MS showed low exposure of the five medicative ingredients. According to the strategy we built, a total of 36 metabolites were found and structurally elucidated. The simultaneously semi-quantitative analysis by LC-MS/MS showed that obvious time-concentration curves could be established for 12 of the metabolites, and most of them showed a relatively higher exposure. This study provides a better understanding of the metabolic processes of GZFL in human.

75 FR 49549 - ABC & D Recycling, Inc.-Lease and Operation Exemption-a Line of Railroad in Ware, MA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-13

... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35397] ABC & D Recycling, Inc.--Lease and Operation Exemption--a Line of Railroad in Ware, MA ABC & D Recycling, Inc. (ABC & D..., ABC & D Recycling, Inc.--Lease and Operation Exemption--a Line of Railroad in Ware, Massachusetts (STB...

The impact of male burials on the construction of Corded Ware identity: Reconstructing networks of information in the 3rd millennium BC.

PubMed

Bourgeois, Quentin; Kroon, Erik

2017-01-01

The emergence of Corded Ware Groups throughout Europe in the 3rd millennium BC is one of the most defining events in European history. From the Wolga to the Rhine communities start to speak Indo-European languages and bury their dead in an extremely similar fashion. Recent ancient DNA-analyses identify a massive migration from the Eurasian steppe as the prime cause for this event. However, there is a fundamental difference between expressing a Corded Ware identity-the sharing of world views and ideas-and having a specific DNA-profile. Therefore, we argue that investigating the exchange of cultural information on burial rites between these communities serves as a crucial complement to the exchange of biological information. By adopting a practice perspective to 1161 Corded Ware burials throughout north-western Europe, combined with similarity indexes and network representations, we demonstrate a high degree of information sharing on the burial ritual between different regions. Moreover, we show that male burials are much more international in character than female burials and as such can be considered as the vector along which cultural information and Corded Ware identity was transmitted. This finding highlights an underlying complex societal organization of Corded Ware burial rites in which gender roles had a significant impact on the composition and transmission of cultural information. Our findings corroborate recent studies that suggest the Corded Ware was a male focused society.

KeyWare: an open wireless distributed computing environment

NASA Astrophysics Data System (ADS)

Shpantzer, Isaac; Schoenfeld, Larry; Grindahl, Merv; Kelman, Vladimir

1995-12-01

Deployment of distributed applications in the wireless domain lack equivalent tools, methodologies, architectures, and network management that exist in LAN based applications. A wireless distributed computing environment (KeyWareTM) based on intelligent agents within a multiple client multiple server scheme was developed to resolve this problem. KeyWare renders concurrent application services to wireline and wireless client nodes encapsulated in multiple paradigms such as message delivery, database access, e-mail, and file transfer. These services and paradigms are optimized to cope with temporal and spatial radio coverage, high latency, limited throughput and transmission costs. A unified network management paradigm for both wireless and wireline facilitates seamless extensions of LAN- based management tools to include wireless nodes. A set of object oriented tools and methodologies enables direct asynchronous invocation of agent-based services supplemented by tool-sets matched to supported KeyWare paradigms. The open architecture embodiment of KeyWare enables a wide selection of client node computing platforms, operating systems, transport protocols, radio modems and infrastructures while maintaining application portability.

76 FR 90 - Antidumping or Countervailing Duty Order, Finding, or Suspended Investigation; Opportunity To...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-03

... Concrete Steel Wire Strand A-580-852 1/1/10--12/31/10 Top-of-the Stove Stainless Steel Cooking Ware\\2\\ A... South Korea: Top-of-the-Stove Stainless Steel Cooking Ware \\3\\ C-580-602 1/1/10--11/21/10 The People's... antidumping duty order on Top-of-the Stove Stainless Steel Cooking Ware was revoked due to sunset review...

Design Enhancements to Facilitate a Sustainable and Energy Efficient Dining Facility (DFAC) in a Contingency Environment

DTIC Science & Technology

2014-09-01

resources, and generate large amounts of food and solid waste daily. Almost all Contingency Basecamp (CB) DFACs provide individual paper and plastic ware...which is costly in terms of purchase, transportation, and disposal. This work analyzed the effects of replacing paper and plastic ware with...reusable materials, and of adding industrial dishwashers to re- duce the logistical burden of using paper and plastic ware. Additional en- hancements

Configuring a Context-Aware Middleware for Wireless Sensor Networks

PubMed Central

Gámez, Nadia; Cubo, Javier; Fuentes, Lidia; Pimentel, Ernesto

2012-01-01

In the Future Internet, applications based on Wireless Sensor Networks will have to support reconfiguration with minimum human intervention, depending on dynamic context changes in their environment. These situations create a need for building these applications as adaptive software and including techniques that allow the context acquisition and decisions about adaptation. However, contexts use to be made up of complex information acquired from heterogeneous devices and user characteristics, making them difficult to manage. So, instead of building context-aware applications from scratch, we propose to use FamiWare, a family of middleware for Ambient Intelligence specifically designed to be aware of contexts in sensor and smartphone devices. It provides both, several monitoring services to acquire contexts from devices and users, and a context-awareness service to analyze and detect context changes. However, the current version of FamiWare does not allow the automatic incorporation related to the management of new contexts into the FamiWare family. To overcome this shortcoming, in this work, we first present how to model the context using a metamodel to define the contexts that must to be taken into account in an instantiation of FamiWare for a certain Ambient Intelligence system. Then, to configure a new context-aware version of FamiWare and to generate code ready-to-install within heterogeneous devices, we define a mapping that automatically transforms metamodel elements defining contexts into elements of the FamiWare family, and we also use the FamiWare configuration process to customize the new context-aware variant. Finally, we evaluate the benefits of our process, and we analyze both that the new version of the middleware works as expected and that it manages the contexts in an efficient way. PMID:23012505

Advantages and disadvantages of using intravenous tissue Plasminogen activator as salvage therapy for inoperable HeartWare thrombosis.

PubMed

Basken, Robyn; Bazzell, Charles M; Smith, Richard; Janardhanan, Rajesh; Khalpey, Zain

2017-07-01

Device thrombosis is a devastating complication of left ventricular assist devices. The definitive treatment has been device exchange or explant. Evidence of increasing morbidity and mortality with device exchange has shifted strategies toward conservative management. In this report, we detail the use of thrombolytics as salvage therapy in a patient with an occlusive HeartWare ventricular assist device (HeartWare Inc., Framingham, MA) thrombus, resulting in long-term survival without further intervention. © 2017 Wiley Periodicals, Inc.

Different surgical strategies for implantation of continuous-flow VADs—Experience from Deutsches Herzzentrum Berlin

PubMed Central

Drews, Thorsten; Potapov, Evgenij; Weng, Yugo; Pasic, Miralem; Hetzer, Roland

2014-01-01

Objective This manuscript summarizes our surgical experience with the implantation of recent continuous-flow left ventricular assist devices (LVADs), with special emphasis on the HeartWare HVAD pump. Methods The HeartWare HVAD is, in our experience currently implanted in four different techniques: (I) “Classical” LVAD implantation with heart-lung machine and median sternotomy; (II) “Minimally-invasive” implantation without sternotomy and without heart-lung machine; (III) “Lateral implantation” to the descending aorta; (IV) Using two continuous-flow LVADs for implantable biventricular support. Results Five-hundred and four HeartWare HVADs have been implanted using the described techniques in our institution up to now. Conclusions The HeartWare HVAD is a versatile device. It has been found to be eminently suited to these four different modes of implantation. PMID:25452906

Superior accuracy of model-based radiostereometric analysis for measurement of polyethylene wear

PubMed Central

Stilling, M.; Kold, S.; de Raedt, S.; Andersen, N. T.; Rahbek, O.; Søballe, K.

2012-01-01

Objectives The accuracy and precision of two new methods of model-based radiostereometric analysis (RSA) were hypothesised to be superior to a plain radiograph method in the assessment of polyethylene (PE) wear. Methods A phantom device was constructed to simulate three-dimensional (3D) PE wear. Images were obtained consecutively for each simulated wear position for each modality. Three commercially available packages were evaluated: model-based RSA using laser-scanned cup models (MB-RSA), model-based RSA using computer-generated elementary geometrical shape models (EGS-RSA), and PolyWare. Precision (95% repeatability limits) and accuracy (Root Mean Square Errors) for two-dimensional (2D) and 3D wear measurements were assessed. Results The precision for 2D wear measures was 0.078 mm, 0.102 mm, and 0.076 mm for EGS-RSA, MB-RSA, and PolyWare, respectively. For the 3D wear measures the precision was 0.185 mm, 0.189 mm, and 0.244 mm for EGS-RSA, MB-RSA, and PolyWare respectively. Repeatability was similar for all methods within the same dimension, when compared between 2D and 3D (all p > 0.28). For the 2D RSA methods, accuracy was below 0.055 mm and at least 0.335 mm for PolyWare. For 3D measurements, accuracy was 0.1 mm, 0.2 mm, and 0.3 mm for EGS-RSA, MB-RSA and PolyWare respectively. PolyWare was less accurate compared with RSA methods (p = 0.036). No difference was observed between the RSA methods (p = 0.10). Conclusions For all methods, precision and accuracy were better in 2D, with RSA methods being superior in accuracy. Although less accurate and precise, 3D RSA defines the clinically relevant wear pattern (multidirectional). PolyWare is a good and low-cost alternative to RSA, despite being less accurate and requiring a larger sample size. PMID:23610688

Stroke and Intracranial Hemorrhage in HeartMate II and HeartWare Left Ventricular Assist Devices: A Systematic Review.

PubMed

Cho, Sung M; Moazami, Nader; Frontera, Jennifer A

2017-08-01

Ischemic stroke and intracranial hemorrhage (ICH) following left ventricular assist device (LVAD) placement are major causes of morbidity. The incidence and mortality associated with these events stratified by device type have not been systematically explored. A systematic review of PubMed was conducted from January 2007 through June 2016 for all English-language articles involving HeartMate II (HMII) and HeartWare LVAD patients. Ischemic stroke and/or ICH incidence (events per patient-year) and associated mortality rates were abstracted for each device type. Of 735 articles reviewed, 48 (11,310 patients) met inclusion criteria (33 HMII, six HeartWare, eight both devices, and one unspecified). The median duration of device support was 112 days (total 13,723 patient-years). Overall, ischemic stroke or ICH occurred in 9.8% (1110 persons and 0.08 events per patient year [EPPY]). Ischemic stroke occurred in a median of 6.0% or 0.06 EPPY (range 0-16% or 0-0.21 EPPY) of HMII patients versus 7.5% or 0.09 EPPY (range 4-17.1% or 0.01-0.94 EPPY) of HeartWare patients. ICH occurred in a median of 3.0% or 0.04 EPPY (range 0-13.5% or 0-0.13 EPPY) of HMII and 8.0% or 0.08 EPPY (range 3-23% or 0.01-0.56 EPPY) of HeartWare patients. The median mortality rate for LVAD-associated ischemic stroke was 31% (HMII: 33%, [range 2.4-75%] and HeartWare: 11.5% [range 3.9-40%]), and the median mortality rate following ICH was 71% (HMII: 75%, [range 3.9-100%] and HeartWare: 44%, [range 3.1-88%]). Ischemic stroke and ICH are common after LVAD placement, but heterogeneous event rates are reported in the literature. Given the high associated mortality, further prospective study is warranted.

XpressWare Installation User guide

NASA Astrophysics Data System (ADS)

Duffey, K. P.

XpressWare is a set of X terminal software, released by Tektronix Inc, that accommodates the X Window system on a range of host computers. The software comprises boot files (the X server image), configuration files, fonts, and font tools to support the X terminal. The files can be installed on one host or distributed across multiple hosts The purpose of this guide is to present the system or network administrator with a step-by-step account of how to install XpressWare, and how subsequently to configure the X terminals appropriately for the environment in which they operate.

Results of the post-market Registry to Evaluate the HeartWare Left Ventricular Assist System (ReVOLVE).

PubMed

Strueber, Martin; Larbalestier, Robert; Jansz, Paul; Zimpfer, Daniel; Fiane, Arnt E; Tsui, Steven; Simon, André; Schmitto, Jan D; Khaghani, Asghar; Wieselthaler, George M; Najarian, Kevin; Schueler, Stephan

2014-05-01

The post-market Registry to Evaluate the HeartWare Left Ventricular Assist System (ReVOLVE) is an investigator-initiated registry established to collect post-CE Mark Trial clinical data on patients receiving a HeartWare ventricular assist device (HVAD) in the European Union and Australia. The ReVOLVE is a multi-center, prospective, single-arm registry performed at seven centers in Europe and two in Australia. Herein we describe a total of 254 commercial HVAD implants according to labeled indications between February 2009 and November 2012. Summary statistics included patients' demographics, adverse events, length of support and outcomes. Compared with the clinical trial supporting the CE Mark of the HeartWare system, patient selection differed in that patients were older, and there were higher proportions of females and patients with idiopathic cardiomyopathies in the ReVOLVE cohort. Duration of support ranged from 1 to 1,057 days, with a mean of 363 ± 280 days (median 299.5 days). Transplantation was done in 56 patients (22%), explant for recovery was performed in 3 patients (1%), 43 died while on support (17%), and 152 (60%) remain on the device. Success in patients with the HeartWare system was 87% at 6 months, 85% at 1 year, 79% at 2 years and 73% at 3 years. Adverse event rates were low, comparable or improved when compared to the CE Mark Trial. Real-world use of the HeartWare system continues to demonstrate excellent clinical outcomes in patients supported with the device. Copyright © 2014 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Star Ware: The Amateur Astronomer's Guide to Choosing, Buying, and Using Telescopes and Accessories, 3rd Edition

NASA Astrophysics Data System (ADS)

Harrington, Philip S.

2002-05-01

Praise for the Second Edition of Star Ware "Star Ware is still a tour de force that any experienced amateur will find invaluable, and which hardware-minded beginners will thoroughly enjoy." -Robert Burnham, Sky & Telescope magazine "Star Ware condenses between two covers what would normally take a telescope buyer many months to accumulate." -John Shibley, Astronomy magazine Now more than ever, the backyard astronomer has a dazzling array of choices when it comes to telescope shopping-which can make choosing just the right sky-watching equipment a formidable challenge. In this revised and updated edition of Star Ware, the essential guide to buying astronomical equipment, award-winning astronomy writer Philip Harrington does the work for you, analyzing and exploring today's astronomy market and offering point-by-point comparisons of everything you need. Whether you're an experienced amateur astronomer or just getting started, Star Ware, Third Edition will prepare you to explore the farthest reaches of space with: Extensive, expanded reviews of leading models and accessories, including dozens of new products, to help you buy smart

75 FR 1333 - Antidumping or Countervailing Duty Order, Finding, or Suspended Investigation; Opportunity To...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-11

... KOREA: Top-of-the Stove Stainless Steel Cooking Ware A-580-601 1/1/09 - 12/31/09 THAILAND: Prestressed...-of-the-Stove Stainless Steel Cooking Ware C-580-602 1/1/09 - 12/31/09 Suspension Agreements MEXICO...

HeartWare HVAD for Biventricular Support in Children and Adolescents: The Stanford Experience.

PubMed

Stein, Mary Lyn; Yeh, Justin; Reinhartz, Olaf; Rosenthal, David N; Kaufman, Beth D; Almond, Chris S; Hollander, Seth A; Maeda, Katsuhide

2016-01-01

Despite increasing use of mechanical circulatory support in children, experience with biventricular device implantation remains limited. We describe our experience using the HeartWare HVAD to provide biventricular support to three patients and compare these patients with five patients supported with HeartWare left ventricular assist device (LVAD). At the end of the study period, all three biventricular assist device (BiVAD) patients had been transplanted and were alive. LVAD patients were out of bed and ambulating a median of 10.5 days postimplantation. The BiVAD patients were out of bed a median of 31 days postimplantation. Pediatric patients with both left ventricular and biventricular heart failure can be successfully bridged to transplantation with the HeartWare HVAD. Rapid improvement in functional status following HVAD implantation for isolated left ventricular support is seen. Patients supported with BiVAD also demonstrate functional recovery, albeit more modestly. In the absence of infection, systemic inflammatory response raises concern for inadequate support.

46 CFR 390.5 - Agreement vessels.

Code of Federal Regulations, 2010 CFR

2010-10-01

... water-borne carriage of men, materials, goods or wares between: (i) Two points in the United States; (ii..., Great Lakes, noncontiguous domestic, or short sea transportation trade. (iv) Engaged primarily in the water-borne carriage of men, materials, goods or wares; and (v) Designated in the agreement as a...

46 CFR 390.5 - Agreement vessels.

Code of Federal Regulations, 2012 CFR

2012-10-01

... water-borne carriage of men, materials, goods or wares between: (i) Two points in the United States; (ii..., Great Lakes, noncontiguous domestic, or short sea transportation trade. (iv) Engaged primarily in the water-borne carriage of men, materials, goods or wares; and (v) Designated in the agreement as a...

46 CFR 390.5 - Agreement vessels.

Code of Federal Regulations, 2013 CFR

2013-10-01

... water-borne carriage of men, materials, goods or wares between: (i) Two points in the United States; (ii..., Great Lakes, noncontiguous domestic, or short sea transportation trade. (iv) Engaged primarily in the water-borne carriage of men, materials, goods or wares; and (v) Designated in the agreement as a...

46 CFR 390.5 - Agreement vessels.

Code of Federal Regulations, 2014 CFR

2014-10-01

... water-borne carriage of men, materials, goods or wares between: (i) Two points in the United States; (ii..., Great Lakes, noncontiguous domestic, or short sea transportation trade. (iv) Engaged primarily in the water-borne carriage of men, materials, goods or wares; and (v) Designated in the agreement as a...

46 CFR 390.5 - Agreement vessels.

Code of Federal Regulations, 2011 CFR

2011-10-01

... water-borne carriage of men, materials, goods or wares between: (i) Two points in the United States; (ii..., Great Lakes, noncontiguous domestic, or short sea transportation trade. (iv) Engaged primarily in the water-borne carriage of men, materials, goods or wares; and (v) Designated in the agreement as a...

78 FR 60245 - Privacy Act Systems of Records; LabWare Laboratory Information Management System

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-01

... Services Laboratories (NVSL). Diagnostic testing provides official test results for animal imports, exports.... Diagnostic testing is also done in connection with suspected foreign animal disease investigations and... of Records; LabWare Laboratory Information Management System AGENCY: Animal and Plant Health...

Improving the Performance of Highly Constrained Water Resource Systems using Multiobjective Evolutionary Algorithms and RiverWare

NASA Astrophysics Data System (ADS)

Smith, R.; Kasprzyk, J. R.; Zagona, E. A.

2015-12-01

Instead of building new infrastructure to increase their supply reliability, water resource managers are often tasked with better management of current systems. The managers often have existing simulation models that aid their planning, and lack methods for efficiently generating and evaluating planning alternatives. This presentation discusses how multiobjective evolutionary algorithm (MOEA) decision support can be used with the sophisticated water infrastructure model, RiverWare, in highly constrained water planning environments. We first discuss a study that performed a many-objective tradeoff analysis of water supply in the Tarrant Regional Water District (TRWD) in Texas. RiverWare is combined with the Borg MOEA to solve a seven objective problem that includes systemwide performance objectives and individual reservoir storage reliability. Decisions within the formulation balance supply in multiple reservoirs and control pumping between the eastern and western parts of the system. The RiverWare simulation model is forced by two stochastic hydrology scenarios to inform how management changes in wet versus dry conditions. The second part of the presentation suggests how a broader set of RiverWare-MOEA studies can inform tradeoffs in other systems, especially in political situations where multiple actors are in conflict over finite water resources. By incorporating quantitative representations of diverse parties' objectives during the search for solutions, MOEAs may provide support for negotiations and lead to more widely beneficial water management outcomes.

CD-ROM Networking: Navigating through VINES and NetWare and the New Software Technologies.

ERIC Educational Resources Information Center

Lieberman, Paula

1995-01-01

Provides an overview of developments in CD-ROM networking technology and describes products offered by Axis, Banyan (VINES--network operating environment), CD Connection, Celerity, Data/Ware, Document Imaging Systems Corporation (DISC), Imagery, Jodian, Meridian, Micro Design International, Microsoft, Microtest, Novell, OnLine Computer Systems,…

Paleo-ocean environments before and after the Ordovician glaciation and the correlation with heterogeneous marine black shale: a stratigraphic case study of Wufeng-Longmaxi formation in Fuling, Sichuan basin, SW China

NASA Astrophysics Data System (ADS)

Lu, Yangbo; Hao, Fang; Lu, Yongchao

2017-04-01

The discovery of Fuling gas field in the Sichuan basin led China shale gas exploration to an unprecedented boom. The most important shale gas plays are the upper Ordovician Wufeng formation and Lower Silurian Longmaxi formation which demonstrate intriguing characteristics which are comprising of stable regional distribution, high abundance of organic matter, high thermal maturity and high brittle mineral content etc. As the Ordovician-Silurian transition was a critical interval in Earth's history marked by dramatic climatic, oceanic, and biological turnovers; these two advantageous organic rich shale deposited before and after Hirnantian glaciation are showing differences in many aspects. In this study, the stratigraphy and lithofacies within the stratigraphy framework of the upper Ordovician Wufeng formation and Lower Silurian Longmaxi formation in Fuling were quantitatively analyzed based on outcrops, cores, well logs data, and geochemical proxies. A total of three third-order sequences were divided based on the recognition of four third-order boundaries. The Wufeng Formation is equivalent to a third-order sequence and is subdivided into a transgressive system tract (TST) (black shale of lower Wufeng Formation) and a highstand system tract (HST) (Guanyinqiao Member of upper Wufeng Formation). Long-1 Member is equivalent to a third-order sequence and is subdivided into a TST, an early highstand system tract (EHST) and a late highstand system tract (LHST); Long-2 and Long-3 Member are combined to be one third-order sequence and is subdivided into a lowstand system tract (LST), a TST and a HST. Sequence development and sedimentary environment characteristics were analyzed within each system tract unit. TOC% was correlated to V/Cr and EF-Ni respectively within each system tract unit, suggesting paleoproductivity and water redox condition are the main controlling factors of organic enrichment and its preservation. The heterogeneity in shale lithofacies throughout the stratigraphic frame work reflects the vertical evolution of the paleo-climate and paleo-ocean environment across the Ordovician-Silurian transition. We suggest that the high primary productivity of Wufeng formation was due to the boom of diatom triggered by large scale coverage of volcanic ash before Hirnantian glaciation. Marine anoxia may have been a kill mechanism that cause the mass extinction of marine macro-organism during the glacial period. And the up sequence TOC deterioration of Longmaxi formation is likely subjected to influence of ocean bottom flow and slow recovery of marine organism after the glaciation.

Impact of OpenCourseWare Publication on Higher Education Participation and Student Recruitment

ERIC Educational Resources Information Center

Carson, Stephen; Kanchanaraksa, Sukon; Gooding, Ira; Mulder, Fred; Schuwer, Robert

2012-01-01

The free and open publication of course materials (OpenCourseWare or OCW) was initially undertaken by Massachusetts Institute of Technology (MIT) and other universities primarily to share educational resources among educators (Abelson, 2007). OCW, however, and more in general open educational resources (OER), have also provided well-documented…

The OpenCourseWare Model: High-Impact Open Educational Content

ERIC Educational Resources Information Center

Carson, Stephen

2007-01-01

OpenCourseWare (OCW) is one among several models for offering open educational resources (OER). This article explains the OCW model and its position within the broader OER context. OCW primarily represents publication of existing course materials already in use for teaching purposes. OCW projects are most often institutional, carrying the…

75 FR 74682 - Antidumping or Countervailing Duty Order, Finding, or Suspended Investigation; Opportunity To...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-01

...-605... 12/1/09-11/30/10 Porcelain-On-Steel Cooking Ware A-583-508........ 12/1/09-11/30/10 Welded Astm... Fittings A-570-881...... 12/1/09-11/30/10 Porcelain-on-Steel Cooking Ware A-570-506........ 12/1/09-11/30...

Fine bakery wares with label claims in Europe and their categorisation by nutrient profiling models.

PubMed

Trichterborn, J; Harzer, G; Kunz, C

2011-03-01

This study assesses a range of commercially available fine bakery wares with nutrition or health related on-pack communication against the criteria of selected nutrient profiling models. Different purposes of the application of nutrient profiles were considered, including front-of-pack signposting and the regulation of claims or advertising. More than 200 commercially available fine bakery wares carrying claims were identified in Germany, France, Spain, Sweden and United Kingdom and evaluated against five nutrient profiling models. All models were assessed regarding their underlying principles, generated results and inter-model agreement levels. Total energy, saturated fatty acids, sugars, sodium and fibre were critical parameters for the categorisation of products. The Choices Programme was the most restrictive model in this category, while the Food and Drug Administration model allowed the highest number of products to qualify. According to all models, more savoury than sweet products met the criteria. On average, qualifying products contained less than half the amounts of nutrients to limit and more than double the amount of fibre compared with all the products in the study. None of the models had a significant impact on the average energy contents. Nutrient profiles can be applied to identify fine bakery wares with a significantly better nutritional composition than the average range of products positioned as healthier. Important parameters to take into account include energy, saturated fatty acids, sugars, sodium and fibre. Different criteria sets for subcategories of fine bakery wares do not seem necessary.

Pots, plates and provenance: sourcing Indian coarse wares from Mleiha using X-ray fluorescence (XRF) spectrometry analysis

NASA Astrophysics Data System (ADS)

Reddy, A.; Attaelmanan, A. G.; Mouton, M.

2012-07-01

The identification of more than 25% of the pottery sherds from the late PIR.D period (ca. 2nd - mid. 3rd c. AD) assemblage from the recently excavated building H at Mleiha as Indian is based on form and fabric, but using only visual assessment. Petrographic analysis of the fabrics can provide more precise indicators of the geographical origin of the wares. In this study, a total of 21 sherds from various key sites in Western India were compared with 7 different 'Indian' coarse-ware vessels sampled at Mleiha using X-ray fluorescence (XRF) spectrometry. The analyses were conducted on powdered samples collected from the core of each sherd. Each sample was irradiated for 1000 seconds using a 1.2 mm diameter X-ray beam. The resulting spectra were used for quantification of the X-ray intensity and elemental concentration. Levels of correlation in the elemental ratios of the sherds were statistically tested using an F-test as well as a Chi-test. Initial review of the XRF results indicates that the Maharashtra and Gujarat regions of India are probable source areas for at least two of the types of wares. Collection of additional samples from these areas and other regions of India, and further statistical analysis through methods such as Principal Component Analysis will help to isolate groups of wares from India and correlate them with types of vessels imported into the Oman peninsula in antiquity.

Modeling Dissolved Solids in the Rincon Valley, New Mexico Using RiverWare

NASA Astrophysics Data System (ADS)

Abudu, S.; Ahn, S. R.; Sheng, Z.

2017-12-01

Simulating transport and storage of dissolved solids in surface water and underlying alluvial aquifer is essential to evaluate the impacts of surface water operations, groundwater pumping, and climate variability on the spatial and temporal variability of salinity in the Rio Grande Basin. In this study, we developed a monthly RiverWare water quantity and quality model to simulate the both concentration and loads of dissolved solids for the Rincon Valley, New Mexico from Caballo Reservoir to Leasburg Dam segment of the Rio Grande. The measured flows, concentration and loads of dissolved solids in the main stream and drains were used to develop RiveWare model using 1980-1988 data for calibration, and 1989-1995 data for validation. The transport of salt is tracked using discretized salt and post-process approaches. Flow and salt exchange between the surface water and adjacent groundwater objects is computed using "soil moisture salt with supplemental flow" method in the RiverWare. In the groundwater objects, the "layered salt" method is used to simulate concentration of the dissolved solids in the shallow groundwater storage. In addition, the estimated local inflows under different weather conditions by using a calibrated Soil Water Assessment Tool (SWAT) were fed into the RiverWare to refine the simulation of the flow and dissolved solids. The results show the salt concentration and loads increased at Leasburg Dam, which indicates the river collects salts from the agricultural return flow and the underlying aquifer. The RiverWare model with the local inflow fed by SWAT delivered the better quantification of temporal and spatial salt exchange patterns between the river and the underlying aquifer. The results from the proposed modeling approach can be used to refine the current mass-balance budgets for dissolved-solids transport in the Rio Grande, and provide guidelines for planning and decision-making to control salinity in arid river environment.

Outcomes of HeartWare Ventricular Assist System support in 141 patients: a single-centre experience.

PubMed

Wu, Long; Weng, Yu-Guo; Dong, Nian-Guo; Krabatsch, Thomas; Stepanenko, Alexander; Hennig, Ewald; Hetzer, Roland

2013-07-01

A third-generation ventricular assist device, the HeartWare Ventricular Assist System, has demonstrated its reliability and durability in animal models and clinical experience. However, studies of a large series of applications are still lacking. We evaluate the safety and efficacy of the HeartWare pump in 141 patients with end-stage heart failure at a single centre. A total of 141 patients (116 men and 25 women with a mean age of 52 years) in New York Heart Association (NYHA) Class IV received implantation of the HeartWare Ventricular Assist System between August 2009 and April 2011 at the Deutsches Herzzentrum Berlin. The outcomes were measured in terms of laboratory data, adverse events, NYHA functional class and survival during device support. The HeartWare system provided an adequate haemodynamic support for patients both inside and outside the hospital. NYHA class improved to I-II. Organ function and pulmonary vascular resistance improved significantly. In this cohort of patients, 14 patients underwent heart transplantation, one had had the device explanted following myocardial recovery, one had changed to another assist device, 81 were on ongoing support and 44 died. The overall actuarial survival rates at 6 and 12 months were 70 and 67%, respectively, and the 3-, 6- and 12-month survival rates on a left ventricular assist device (LVAD) support for bridge to transplantation patients were 82, 81 and 79%, respectively. Infection and bleeding were the main adverse events. Four patients underwent an LVAD exchange for pump thrombosis. The HeartWare system provides a safe and effective circulatory support in a population with a wide range of body surface areas, with a satisfactory actuarial survival time and an improved quality of life. It can be used for univentricular or biventricular support, being implanted into the pericardial space with simplified surgical techniques.

The radiological impact of electricity generation by U.K. coal and nuclear systems.

PubMed

Robson, A

1984-05-01

Radiological impact is discussed for U.K. coal and nuclear power cycles under normal operation. The type having the greater impact depends on the radiological basis of the comparison, the particular nuclear reactor system considered and whether or not the whole fuel cycle, especially irradiated nuclear fule reprocessing , is included in the analysis. More importantly, the various impacts are shown to be generally acceptable in an absolute sense i.e. exposures are less than and usually low in comparison with radiological safety guidelines and everyday natural radiation exposures.

Positioning New Patterns of Privilege in Learning: A Response to Ware

ERIC Educational Resources Information Center

Paxton-Buursma, Debra J.; Mariage, Troy V.

2011-01-01

This special series represents collective courage because what is willing to be risked may be profound. At center is a willingness to reach out and cultivate new conversations on disability. Indeed, the artists who contribute to Ware's article are key co-authors; their art ushers us into a new disability literacy that extends and challenges…

On the Waring problem for polynomial rings

PubMed Central

Fröberg, Ralf; Ottaviani, Giorgio; Shapiro, Boris

2012-01-01

In this note we discuss an analog of the classical Waring problem for . Namely, we show that a general homogeneous polynomial of degree divisible by k≥2 can be represented as a sum of at most kn k-th powers of homogeneous polynomials in . Noticeably, kn coincides with the number obtained by naive dimension count. PMID:22460787

OpenCourseWare Resources for Advanced High School Study

ERIC Educational Resources Information Center

Carson, Steve

2008-01-01

In 2000, the Massachusetts Institute of Technology (MIT) faculty first proposed putting the course materials from all 1,800 MIT classes online, free of charge. The idea behind MIT OpenCourseWare (OCW) was to use the Internet for more than just distance learning. When MIT began placing the course materials online in 2002 and 2003, the audience…

The OpenCourseWare Story: New England Roots, Global Reach

ERIC Educational Resources Information Center

Carson, Stephen

2008-01-01

The OpenCourseWare movement has its roots in New England. The concept emerged in 2000 at Massachusetts Institute of Technology (MIT) where then-President Charles Vest charged a faculty committee with answering two questions: "How is the Internet going to change education?" and "What should MIT do about it?" MIT moved quickly to…

Impact of Shale Gas Development on Water Resource in Fuling, China

NASA Astrophysics Data System (ADS)

Yang, Hong; Huang, Xianjin; Yang, Qinyuan; Tu, Jianjun

2015-04-01

As a low-carbon energy, shale gas rapidly developed in U.S. in last years due to the innovation of the technique of hydraulic fracture, or fracking. Shale gas boom produces more gas with low price and reduced the reliance on fuel import. To follow the American shale gas success, China made an ambitious plan of shale gas extraction, 6.5 billion m3 by 2015. To extract shale gas, huge amount water is needed to inject into each gas well. This will intensify the competition of water use between industry, agricultural and domestic sectors. It may finally exacerbate the water scarcity in China. After the extraction, some water was returned to the ground. Without adequate treatment, the flowback water can introduce heavy metal, acids, pesticides, and other toxic material into water and land. This may inevitably worsen the water and land contamination. This study analysed the potential water consumption and wastewater generation in shale gas development in Fuling, Southwest China. The survey found the average water consumption is 30,000 cubic meter for one well, higher than shale well in U.S. Some 2%-20% water flowed back to the ground. The water quality monitoring showed the Total Suspended Solid (TSS) and Chemical Oxygen Demand (COD) were the main factors above those specified by China's water regulation. Shale gas is a lower-carbon energy, but it is important to recognize the water consuming and environmental pollution during the fracking. Strict monitoring and good coordination during the shale gas exploitation is urgently needed for the balance of economic development, energy demand and environmental protection.

Second Language Vocabulary Acquisition from Language Input and from Form-Focused Activities

ERIC Educational Resources Information Center

Laufer, Batia

2009-01-01

Interest in L2 vocabulary learning and teaching started long before the nineteen-eighties (for references to earlier studies, see Rob Waring's database http://www1.harenet.ne.jp/~waring/vocab/vocrefs/vocref.html) but it declined with the advent of generative linguistics to the point of discrimination and neglect (Meara 1980). In 1986, I argued…

Evaluating NTU's OpenCourseWare Project with Google Analytics: User Characteristics, Course Preferences, and Usage Patterns

ERIC Educational Resources Information Center

Sheu, Feng-Ru; Shih, Meilun

2017-01-01

As freely adoptable digital resources, OpenCourseWare (OCW) have become a prominent form of Open Educational Resources (OER). More than 275 institutions in the worldwide OCW consortium have committed to creating free access open course materials. Despite the resources and efforts to create OCW worldwide, little understanding of its use exists.…

Challenges in the Adoption and Use of OpenCourseWare: Experience of the United Nations University

ERIC Educational Resources Information Center

Barrett, Brendan F. D.; Grover, Velma I.; Janowski, Tomasz; van Lavieren, Hanneke; Ojo, Adegboyega; Schmidt, Philipp

2009-01-01

This paper provides insights on the adoption or use of OpenCourseWare (OCW) to support broader research, training and institutional capacity development goals, based on the experience of the United Nations University. Specifically, it explains the strategic context for the use of OCW in the university through its related efforts in the area of…

75 FR 11991 - ABC & D Recycling, Inc.-Lease and Operation Exemption-a Line of Railroad in Ware, MA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-12

... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [STB Finance Docket No. 35356] ABC & D Recycling, Inc.--Lease and Operation Exemption--a Line of Railroad in Ware, MA ABC & D Recycling, Inc. (ABC & D), a noncarrier, has filed a verified notice of exemption under 49 CFR 1150.31 to lease from O...

OpenCourseWare, Global Access and the Right to Education: Real Access or Marketing Ploy?

ERIC Educational Resources Information Center

Huijser, Henk; Bedford, Tas; Bull, David

2008-01-01

This paper explores the potential opportunities that OpenCourseWare (OCW) offers in providing wider access to tertiary education, based on the ideal of "the right to education." It first discusses the wider implications of OCW, and its underlying philosophy, before using a case study of a tertiary preparation program (TPP) at the…

OpenCourseWare and Open Educational Resources: The Next Big Thing in Technology-Enhanced Education?

ERIC Educational Resources Information Center

Caudill, Jason G.

2012-01-01

OpenCourseWare (OCW) and Open Educational Resources (OER) are two new and closely related educational technologies. Both provide open access to learning materials for students and instructors via the Internet. These are for the moment still very young technologies. While they have grown dramatically in just ten years there is still relatively…

Explaining the Paradox: Perceived Instructor Benefits and Costs of Contributing to Massachusetts Institute of Technology OpenCourseWare

ERIC Educational Resources Information Center

Parker, Preston Paul

2011-01-01

This study examines perceived benefits and costs of instructors who contributed to the Massachusetts Institute of Technology (MIT) OpenCourseWare (OCW) project. While previous research has investigated the benefits and costs of OCW from the perspectives of the users and institution, the instructor's perspective is the focus of this qualitative…

Understanding the Self-Directed Online Learning Preferences, Goals, Achievements, and Challenges of MIT OpenCourseWare Subscribers

ERIC Educational Resources Information Center

Bonk, Curtis J.; Lee, Mimi Miyoung; Kou, Xiaojing; Xu, Shuya; Sheu, Feng-Ru

2015-01-01

This research targeted the learning preferences, goals and motivations, achievements, challenges, and possibilities for life change of self-directed online learners who subscribed to the monthly OpenCourseWare (OCW) e-newsletter from MIT. Data collection included a 25-item survey of 1,429 newsletter subscribers; 613 of whom also completed an…

It Is More than Knowledge Seeking: Examining the Effects of OpenCourseWare Lectures on Vocabulary Acquisition in English as a Foreign Language (EFL) Context

ERIC Educational Resources Information Center

Yang, Hui-Chi; Sun, Yu-Chih

2013-01-01

OpenCourseWare (OCW) has received increasing attention over the past few years in higher education. These courses provide appealing opportunities to view classes taught in well-established universities worldwide. The current study aims to examine how OCW lectures can serve as authentic learning materials to facilitate vocabulary acquisition for…

Advanced vehicle systems assessment. Volume 4: Supporting analyses

NASA Technical Reports Server (NTRS)

Hardy, K.

1985-01-01

Volume 4 (Supporting Analyses) is part of a five-volume report, Advanced Vehicle Systems Assessment. Thirty-nine individuals, knowledgeable in advanced technology, were interviewed to obtain their preferences. Rankings were calculated for the eight groups they represented, using multiplicative and additive utility models. The four topics for consideration were: (1) preferred range for various battery technologies; (2) preferred battery technology for each of a variety of travel ranges; (3) most promising battery technology, vehicle range combination; and (4) comparison of the most preferred electric vehicle with the methanol-fuled, spark-ignition engine vehicle and with the most preferred of the hybrid vehicles.

The Kinome of Edible and Medicinal Fungus Wolfiporia cocos

PubMed Central

Wei, Wei; Shu, Shaohua; Zhu, Wenjun; Xiong, Ying; Peng, Fang

2016-01-01

Wolfiporia cocos is an edible and medicinal fungus that grows in association with pine trees, and its dried sclerotium, known as Fuling in China, has been used as a traditional medicine in East Asian countries for centuries. Nearly 10% of the traditional Chinese medicinal preparations contain W. cocos. Currently, the commercial production of Fuling is limited because of the lack of pine-based substrate and paucity of knowledge about the sclerotial development of the fungus. Since protein kinase (PKs) play significant roles in the regulation of growth, development, reproduction, and environmental responses in filamentous fungi, the kinome of W. cocos was analyzed by identifying the PKs genes, studying transcript profiles and assigning PKs to orthologous groups. Of the 10 putative PKs, 11 encode atypical PKs, and 13, 10, 2, 22, and 11 could encoded PKs from the AGC, CAMK, CK, CMGC, STE, and TLK Groups, respectively. The level of transcripts from PK genes associated with sclerotia formation in the mycelium and sclerotium stages were analyzed by qRT-PCR. Based on the functions of the orthologs in Sclerotinia sclerotiorum (a sclerotia-formation fungus) and Saccharomyces cerevisiae, the potential roles of these W. cocos PKs were assigned. To the best of our knowledge, our study is the first identification and functional discussion of the kinome in the edible and medicinal fungus W. cocos. Our study systematically suggests potential roles of W. cocos PKs and provide comprehensive and novel insights into W. cocos sclerotial development and other economically important traits. Additionally, based on our result, genetic engineering can be employed for over expression or interference of some significant PKs genes to promote sclerotial growth and the accumulation of active compounds. PMID:27708635

Saylorville Stage 3 Contract Completion Report: Testing of Priority 1 Archaeological Sites 1980-1981.

DTIC Science & Technology

1982-02-01

ware porcelain vessel fragments 26 23 3 25 1 - - Porcelain "china" doll fragments 3 3 - 3 - - Porcelain door knob A insulator fraqments 6 6 - 6...34 doll fragments 3 3 - 3 - Porcelain door knob & insulator fraqments 6 6 - 6 - Decorated & white ware ironstone vessel fragments 85 82 3 85 - Stoneware...77 - - - - Stoneware or kaolin pipe fragments 2 2 - - 2 - - - - Porcelain insulator fragment 1 1 - - I - - - - Glazed brick fraqment I I - - I

Localized soft elasticity in liquid crystal elastomers (POSTPRINT)

DTIC Science & Technology

2016-02-23

AFRL-RX-WP-JA-2016-0280 LOCALIZED SOFT ELASTICITY IN LIQUID CRYSTAL ELASTOMER (POSTPRINT) Taylor H. Ware, Andreas F. Shick, and...MM-YY) 2. REPORT TYPE 3. DATES COVERED (From - To) 11 August 2015 Interim 31 January 2014 – 11 July 2015 4. TITLE AND SUBTITLE LOCALIZED SOFT ...2016 Localized soft elasticity in liquid crystal elastomers Taylor H. Ware1,2, John S. Biggins3, Andreas F. Shick1, Mark Warner3 & Timothy J. White1

Metalorganic vapor phase epitaxy of AlN on sapphire with low etch pit density

NASA Astrophysics Data System (ADS)

Koleske, D. D.; Figiel, J. J.; Alliman, D. L.; Gunning, B. P.; Kempisty, J. M.; Creighton, J. R.; Mishima, A.; Ikenaga, K.

2017-06-01

Using metalorganic vapor phase epitaxy, methods were developed to achieve AlN films on sapphire with low etch pit density (EPD). Key to this achievement was using the same AlN growth recipe and only varying the pre-growth conditioning of the quartz-ware. After AlN growth, the quartz-ware was removed from the growth chamber and either exposed to room air or moved into the N2 purged glove box and exposed to H2O vapor. After the quartz-ware was exposed to room air or H2O, the AlN film growth was found to be more reproducible, resulting in films with (0002) and (10-12) x-ray diffraction (XRD) rocking curve linewidths of 200 and 500 arc sec, respectively, and EPDs < 100 cm-2. The EPD was found to correlate with (0002) linewidths, suggesting that the etch pits are associated with open core screw dislocations similar to GaN films. Once reproducible AlN conditions were established using the H2O pre-treatment, it was found that even small doses of trimethylaluminum (TMAl)/NH3 on the quartz-ware surfaces generated AlN films with higher EPDs. The presence of these residual TMAl/NH3-derived coatings in metalorganic vapor phase epitaxy (MOVPE) systems and their impact on the sapphire surface during heating might explain why reproducible growth of AlN on sapphire is difficult.

[Study on extraction technology of soyasaponins from residual of bean ware].

PubMed

Lu, Rumei; Zhang, Yizhen; Bi, Yi

2003-04-01

To find out the optimum extraction technology of soyasaponins from residual of bean ware. The optimum extraction conditions were investigated by the orthogonal design, and the content of soyasaponins was determined by UV-spectro-pho-tometry. The optimum extraction technology was A3B1C1, that is adding 7 times and 6 times amount of 70% alcohol and refluxing for two times and each time for 1.0 h. The selected technology showed higher yield of soyasaponins, good stability and high efficient.

Cenozoic Antarctic DiatomWare/BugCam: An aid for research and teaching

USGS Publications Warehouse

Wise, S.W.; Olney, M.; Covington, J.M.; Egerton, V.M.; Jiang, S.; Ramdeen, D.K.; ,; Schrader, H.; Sims, P.A.; Wood, A.S.; Davis, A.; Davenport, D.R.; Doepler, N.; Falcon, W.; Lopez, C.; Pressley, T.; Swedberg, O.L.; Harwood, D.M.

2007-01-01

Cenozoic Antarctic DiatomWare/BugCam© is an interactive, icon-driven digital-image database/software package that displays over 500 illustrated Cenozoic Antarctic diatom taxa along with original descriptions (including over 100 generic and 20 family-group descriptions). This digital catalog is designed primarily for use by micropaleontologists working in the field (at sea or on the Antarctic continent) where hard-copy literature resources are limited. This new package will also be useful for classroom/lab teaching as well as for any paleontologists making or refining taxonomic identifications at the microscope. The database (Cenozoic Antarctic DiatomWare) is displayed via a custom software program (BugCam) written in Visual Basic for use on PCs running Windows 95 or later operating systems. BugCam is a flexible image display program that utilizes an intuitive thumbnail “tree” structure for navigation through the database. The data are stored on Micrsosoft EXCEL spread sheets, hence no separate relational database program is necessary to run the package

The medium is NOT the message or Indefinitely long-term file storage at Leeds University

NASA Technical Reports Server (NTRS)

Holdsworth, David

1996-01-01

Approximately 3 years ago we implemented an archive file storage system which embodies experiences gained over more than 25 years of using and writing file storage systems. It is the third in-house system that we have written, and all three systems have been adopted by other institutions. This paper discusses the requirements for long-term data storage in a university environment, and describes how our present system is designed to meet these requirements indefinitely. Particular emphasis is laid on experiences from past systems, and their influence on current system design. We also look at the influence of the IEEE-MSS standard. We currently have the system operating in five UK universities. The system operates in a multi-server environment, and is currently operational with UNIX (SunOS4, Solaris2, SGI-IRIX, HP-UX), NetWare3 and NetWare4. PCs logged on to NetWare can also archive and recover files that live on their hard disks.

Characterization of newfound natural luminescent properties of melamine, and development and validation of a method of high performance liquid chromatography with fluorescence detection for its determination in kitchen plastic ware.

PubMed

Finete, Virginia de Lourdes Mendes; Gouvêa, Marcos Martins; Marques, Flávia Ferreira de Carvalho; Netto, Annibal Duarte Pereira

2014-06-01

Experimental studies of the natural photoluminescence of melamine in aqueous solutions showed that its fluorescence intensity (at 250/365 nm) was appropriated for analytical purposes. The exploitation of such melamine property provided the basis of development of a new, simple, precise and accurate method based on high performance liquid chromatography with fluorescence detection (HPLC-Fluo) to determine melamine in kitchen plastic ware following aqueous extraction using a microwave oven. Optimization of analytical parameters such as solvent composition, pH and extraction conditions led to limits of detection and quantification of melamine of 0.0081 and 0.027 μg mL(-1), respectively, with a linear range up to 10 μg mL(-1). Sample extracts fortified with melamine at three concentration levels produced an average recovery of 98±6%, which was in agreement with the results achieved with a reference HPLC-UV method. Different samples of kitchen plastic ware analyzed by the developed and optimized method showed melamine concentrations in the aqueous extract up to 17 µg mL(-1), which corresponded to 86.0 mg kg(-1) in these utensils. The results obtained indicate that the use of kitchen plastic ware made of melamine can contaminate food with this compound after heating in a microwave oven. Copyright © 2014. Published by Elsevier B.V.

SeqWare Query Engine: storing and searching sequence data in the cloud.

PubMed

O'Connor, Brian D; Merriman, Barry; Nelson, Stanley F

2010-12-21

Since the introduction of next-generation DNA sequencers the rapid increase in sequencer throughput, and associated drop in costs, has resulted in more than a dozen human genomes being resequenced over the last few years. These efforts are merely a prelude for a future in which genome resequencing will be commonplace for both biomedical research and clinical applications. The dramatic increase in sequencer output strains all facets of computational infrastructure, especially databases and query interfaces. The advent of cloud computing, and a variety of powerful tools designed to process petascale datasets, provide a compelling solution to these ever increasing demands. In this work, we present the SeqWare Query Engine which has been created using modern cloud computing technologies and designed to support databasing information from thousands of genomes. Our backend implementation was built using the highly scalable, NoSQL HBase database from the Hadoop project. We also created a web-based frontend that provides both a programmatic and interactive query interface and integrates with widely used genome browsers and tools. Using the query engine, users can load and query variants (SNVs, indels, translocations, etc) with a rich level of annotations including coverage and functional consequences. As a proof of concept we loaded several whole genome datasets including the U87MG cell line. We also used a glioblastoma multiforme tumor/normal pair to both profile performance and provide an example of using the Hadoop MapReduce framework within the query engine. This software is open source and freely available from the SeqWare project (http://seqware.sourceforge.net). The SeqWare Query Engine provided an easy way to make the U87MG genome accessible to programmers and non-programmers alike. This enabled a faster and more open exploration of results, quicker tuning of parameters for heuristic variant calling filters, and a common data interface to simplify development of analytical tools. The range of data types supported, the ease of querying and integrating with existing tools, and the robust scalability of the underlying cloud-based technologies make SeqWare Query Engine a nature fit for storing and searching ever-growing genome sequence datasets.

SeqWare Query Engine: storing and searching sequence data in the cloud

PubMed Central

2010-01-01

Background Since the introduction of next-generation DNA sequencers the rapid increase in sequencer throughput, and associated drop in costs, has resulted in more than a dozen human genomes being resequenced over the last few years. These efforts are merely a prelude for a future in which genome resequencing will be commonplace for both biomedical research and clinical applications. The dramatic increase in sequencer output strains all facets of computational infrastructure, especially databases and query interfaces. The advent of cloud computing, and a variety of powerful tools designed to process petascale datasets, provide a compelling solution to these ever increasing demands. Results In this work, we present the SeqWare Query Engine which has been created using modern cloud computing technologies and designed to support databasing information from thousands of genomes. Our backend implementation was built using the highly scalable, NoSQL HBase database from the Hadoop project. We also created a web-based frontend that provides both a programmatic and interactive query interface and integrates with widely used genome browsers and tools. Using the query engine, users can load and query variants (SNVs, indels, translocations, etc) with a rich level of annotations including coverage and functional consequences. As a proof of concept we loaded several whole genome datasets including the U87MG cell line. We also used a glioblastoma multiforme tumor/normal pair to both profile performance and provide an example of using the Hadoop MapReduce framework within the query engine. This software is open source and freely available from the SeqWare project (http://seqware.sourceforge.net). Conclusions The SeqWare Query Engine provided an easy way to make the U87MG genome accessible to programmers and non-programmers alike. This enabled a faster and more open exploration of results, quicker tuning of parameters for heuristic variant calling filters, and a common data interface to simplify development of analytical tools. The range of data types supported, the ease of querying and integrating with existing tools, and the robust scalability of the underlying cloud-based technologies make SeqWare Query Engine a nature fit for storing and searching ever-growing genome sequence datasets. PMID:21210981

Learning from the past: Rare ε-Fe2O3 in the ancient black-glazed Jian (Tenmoku) wares

PubMed Central

Dejoie, Catherine; Sciau, Philippe; Li, Weidong; Noé, Laure; Mehta, Apurva; Chen, Kai; Luo, Hongjie; Kunz, Martin; Tamura, Nobumichi; Liu, Zhi

2014-01-01

Ancient Jian wares are famous for their lustrous black glaze that exhibits unique colored patterns. Some striking examples include the brownish colored “Hare's Fur” (HF) strips and the silvery “Oil Spot” (OS) patterns. Herein, we investigated the glaze surface of HF and OS samples using a variety of characterization methods. Contrary to the commonly accepted theory, we identified the presence of ε-Fe2O3, a rare metastable polymorph of Fe2O3 with unique magnetic properties, in both HF and OS samples. We found that surface crystals of OS samples are up to several micrometers in size and exclusively made of ε-Fe2O3. Interestingly, these ε-Fe2O3 crystals on the OS sample surface are organized in a periodic two dimensional fashion. These results shed new lights on the actual mechanisms and kinetics of polymorphous transitions of Fe2O3. Deciphering technologies behind the fabrication of ancient Jian wares can thus potentially help researchers improve the ε-Fe2O3 synthesis. PMID:24820819

[Analysis of on medication rules for Qi-deficiency and blood-stasis syndrome of chronic heart failure based on data mining technology].

PubMed

Wang, Qian; Yao, Geng-Zhen; Pan, Guang-Ming; Huang, Jing-Yi; An, Yi-Pei; Zou, Xu

2017-01-01

To analyze the medication features and the regularity of prescriptions of traditional Chinese medicine in treating patients with Qi-deficiency and blood-stasis syndrome of chronic heart failure based on modern literature. In this article, CNKI Chinese academic journal database, Wanfang Chinese academic journal database and VIP Chinese periodical database were all searched from January 2000 to December 2015 for the relevant literature on traditional Chinese medicine treatment for Qi-deficiency and blood-stasis syndrome of chronic heart failure. Then a normalized database was established for further data mining and analysis. Subsequently, the medication features and the regularity of prescriptions were mined by using traditional Chinese medicine inheritance support system(V2.5), association rules, improved mutual information algorithm, complex system entropy clustering and other mining methods. Finally, a total of 171 articles were included, involving 171 prescriptions, 140 kinds of herbs, with a total frequency of 1 772 for the herbs. As a result, 19 core prescriptions and 7 new prescriptions were mined. The most frequently used herbs included Huangqi(Astragali Radix), Danshen(Salviae Miltiorrhizae Radix et Rhizoma), Fuling(Poria), Renshen(Ginseng Radix et Rhizoma), Tinglizi(Semen Lepidii), Baizhu(Atractylodis Macrocephalae Rhizoma), and Guizhi(Cinnamomum Ramulus). The core prescriptions were composed of Huangqi(Astragali Radix), Danshen(Salviae Miltiorrhizae Radix et Rhizoma) and Fuling(Poria), etc. The high frequent herbs and core prescriptions not only highlight the medication features of Qi-invigorating and blood-circulating therapy, but also reflect the regularity of prescriptions of blood-circulating, Yang-warming, and urination-promoting therapy based on syndrome differentiation. Moreover, the mining of the new prescriptions provide new reference and inspiration for clinical treatment of various accompanying symptoms of chronic heart failure. In conclusion, this article provides new reference for traditional Chinese medicine in the treatment of chronic heart failure. Copyright© by the Chinese Pharmaceutical Association.

[Using Raman spectrum analysis to research corrosive productions occurring in alloy of ancient bronze wares].

PubMed

Jia, La-jiang; Jin, Pu-jun

2015-01-01

The present paper analyzes the interior rust that occurred in bronze alloy sample from 24 pieces of Early Qin bronze wares. Firstly, samples were processed by grinding, polishing and ultrasonic cleaning-to make a mirror surface. Then, a confocal micro-Raman spectrometer was employed to carry out spectroscopic study on the inclusions in samples. The conclusion indicated that corrosive phases are PbCO3 , PbO and Cu2O, which are common rusting production on bronze alloy. The light-colored circular or massive irregular areas in metallographic structure of samples are proved as Cu2O, showing that bronze wares are not only easy to be covered with red Cu2O rusting layer, but also their alloy is easy to be eroded by atomic oxygen. In other words, the rust Cu2O takes place in both the interior and exterior parts of the bronze alloy. In addition, Raman spectrum analysis shows that the dark grey materials are lead corrosive products--PbCO3 and PbO, showing the corroding process of lead element as Pb -->PbO-->PbCO3. In the texture of cast state of bronze alloy, lead is usually distributed as independent particles between the different alloy phases. The lead particles in bronze alloy would have oxidation reaction and generate PbO when buried in the soil, and then have chemical reaction with CO3(2-) dissolved in the underground water to generate PbCO3, which is a rather stable lead corrosive production. A conclusion can be drawn that the external corrosive factors (water, dissolved oxygen and carbonate, etc) can enter the bronze ware interior through the passageway between different phases and make the alloy to corrode gradually.

Minimally Invasive Implantation of HeartWare Assist Device and Simultaneous Tricuspid Valve Reconstruction Through Partial Upper Sternotomy.

PubMed

Hillebrand, Julia; Hoffmeier, Andreas; Djie Tiong Tjan, Tonny; Sindermann, Juergen R; Schmidt, Christoph; Martens, Sven; Scherer, Mirela

2017-05-01

Left ventricular assist device (LVAD) implantation is a well-established therapy to support patients with end-stage heart failure. However, the operative procedure is associated with severe trauma. Third generation LVADs like the HeartWare assist device (HeartWare, Inc., Framingham, MA, USA) are characterized by enhanced technology despite smaller size. These devices offer new minimally invasive surgical options. Tricuspid regurgitation requiring valve repair is frequent in patients with the need for mechanical circulatory support as it is strongly associated with ischemic and nonischemic cardiomyopathy. We report on HeartWare LVAD implantation and simultaneous tricuspid valve reconstruction through minimally invasive access by partial upper sternotomy to the fifth left intercostal space. Four male patients (mean age 51.72 ± 11.95 years) suffering from chronic heart failure due to dilative (three patients) and ischemic (one patient) cardiomyopathy and also exhibiting concomitant tricuspid valve insufficiency due to annular dilation underwent VAD implantation and tricuspid valve annuloplasty. Extracorporeal circulation was established via the ascending aorta, superior vena cava, and right atrium. In all four cases the LVAD implantation and tricuspid valve repair via partial median sternotomy was successful. During the operative procedure, no conversion to full sternotomy was necessary. One patient needed postoperative re-exploration because of pericardial effusion. No postoperative focal neurologic injury was observed. New generation VADs are advantageous because of the possibility of minimally invasive implantation procedure which can therefore minimize surgical trauma. Concomitant tricuspid valve reconstruction can also be performed simultaneously through partial upper sternotomy. Nevertheless, minimally invasive LVAD implantation is a challenging operative technique. © 2016 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

A study on the oil-based drilling cutting pyrolysis residue resource utilization by the exploration and development of shale gas.

PubMed

Wang, Chao-Qiang; Jin, Ji-Zhong; Lin, Xiao-Yan; Xiong, De-Ming; Mei, Xu-Dong

2017-07-01

Based on the requirement of national energy conservation and environmental protection, attention has been given to building an environment-friendly and resource-saving society. Shale gas oil-based drilling cutting pyrolysis residues (ODPRs) have been used as the main research object to developing new technology which can convert the residues into a harmless and recyclable material. Using the test data of ODPR, we analyze the development prospect in the building material industry and provide a scheme to utilize this particular solid-waste efficiently. Theoretically speaking, the ODPR resource utilization such as admixture of cement, making sintered brick, and non-fired brick, by the exploration and development of Fuling shale gas is feasible.

[Antimony and other heavy metals in metallic kitchen ware].

PubMed

Ishiwata, H; Sugita, T; Yoshihira, K

1989-01-01

The antimony in metallic kitchen ware was determined. The content of this element in metals used for the production or repairing of utensils, containers and packaging which come in contact with foods is regulated and should be less than 5% in under the Japanese Food Sanitation Law. In eight metallic samples, antimony was detected in solder used for the production of a can for green tea and an eggbeater. The contents were 1.30% in the former and 1.90% in the latter. No antimony was detected in solder used for a cookie cutter. A sample of solder used for electric work, not for food utensils, contained 0.81% of antimony. In other metallic utensils which come in contact with food such as aluminum foil, a brass spoon, a stainless steel fork, a wire netting, and an iron rock for vegetable color stabilizing, antimony was not detected at a 0.05% detection limit. A qualitative test using rhodamine B also showed positive results in only three solder samples. Lead concentrations in solder used for the kitchen ware were from 39.3 to 51.3%. These concentrations were higher than the limit (20%) of lead content by the Law. No cadmium was detected in any samples.

Provenance analysis of the Pliocene Ware Formation in the Guajira Peninsula, northern Colombia: Paleodrainage implications

NASA Astrophysics Data System (ADS)

Pérez-Consuegra, Nicolás; Parra, Mauricio; Jaramillo, Carlos; Silvestro, Daniele; Echeverri, Sebastián; Montes, Camilo; Jaramillo, José María; Escobar, Jaime

2018-01-01

The Cocinetas Basin in the Guajira Peninsula, the northernmost tip of South America, today has a dry climate with low rainfall (<500 mm/yr), a long dry season (>ten months) and no year-long rivers or permanent standing bodies of fresh water. In contrast, the fossil and geological record indicate that the Cocinetas Basin was much wetter during the Miocene-Pliocene (∼17-2.8 Ma). Water needed to sustain the paleofauna could either have originated from local sources or been brought by a larger river system (e.g. proto Magdalena/Orinoco river) with headwaters either in Andean ranges or the Guyana shield. We present a provenance study of the Pliocene Ware Formation, using petrographic analysis of conglomerate clasts and heavy minerals, and U-Pb dating of 140 detrital zircons. Clasts and heavy minerals are typical of ensialic metamorphic and igneous sources. The detrital zircon age distribution indicates the Guajira ranges as the most probable sediment source. The overall results indicate that the fluvial system of the Ware Formation drained the surrounding ranges. The water was probably derived by local precipitation onto the Guajira peninsula.

Study on the property of the production for Fengdongyan kiln in Early Ming dynasty by INAA and EDXRF

NASA Astrophysics Data System (ADS)

Li, L.; Huang, Y.; Sun, H. Y.; Yan, L. T.; Feng, S. L.; Xu, Q.; Feng, X. Q.

2016-08-01

A lot of official wares carved "Guan" or the dragon patterns were excavated on the strata of Ming dynasty of the Fengdongyan kiln site at Dayao County. The imperial porcelain was fired in Hongwu and Yongle eras. However, the emergence of this imperial porcelain has triggered academic debate about the property of Fengdongyan kiln in the Early Ming dynasty. Based on the differences of the official kiln management, some scholars have determined that the property of the production for this kiln was the civilian kiln. According to the historical textural records and typology, others preliminary confirmed that Fengdongyan kiln was the official kiln. In this paper, the elemental compositions of body and glaze in imperial and civilian porcelain are study by INAA and EDXRF for determining the property of the production for this kiln in Early Ming dynasty. After the processing of experimental data by geochemical analysis and principal component analysis, the result show that the raw materials for making body and glaze in imperial porcelain are similar with those of the civilian porcelain and the degrees of elutriation for body can be slightly different in HW-M period of Ming dynasty. The analytical results support the view that the Fengdongyan kiln is civilian not official.

PRODUCTION OF THORIA WARE

DOEpatents

Murray, P.; Denton, I.; Wilkinson, D.

1957-10-01

The production of thoria ware of very low porosity by the slip casting of pure thoria is described. It comprises dry milling calcined thoria to obtain particles ranging up to 11 microns in size and having 60% of particles less than 2 microns, forming an aqueous slip of the milled thoric casting the slip and firing the dry cast at a sintering temperature of from 1600 to 1825 d C. The preferred composition of the slip is 1600 grams of thoria in each liter of slip. The preferred pH of the slip is 1. When thoria of 99.9% purity is used the slip is suitable for casting for as long as six weeks after preparation.

Adsorption of Ten Microcystin Congeners to Common Laboratory-Ware Is Solvent and Surface Dependent.

PubMed

Altaner, Stefan; Puddick, Jonathan; Wood, Susanna A; Dietrich, Daniel R

2017-04-06

Cyanobacteria can produce heptapetides called microcystins (MC) which are harmful to humans due to their ability to inhibit cellular protein phosphatases. Quantitation of these toxins can be hampered by their adsorption to common laboratory-ware during sample processing and analysis. Because of their structural diversity (>100 congeners) and different physico-chemical properties, they vary in their adsorption to surfaces. In this study, the adsorption of ten different MC congeners (encompassing non-arginated to doubly-arginated congeners) to common laboratory-ware was assessed using different solvent combinations. Sample handling steps were mimicked with glass and polypropylene pipettes and vials with increasing methanol concentrations at two pH levels, before analysis by liquid chromatography-tandem mass spectrometry. We demonstrated that MC adsorb to polypropylene surfaces irrespective of pH. After eight successive pipet actions using polypropylene tips ca. 20% of the MC were lost to the surface material, which increased to 25%-40% when solutions were acidified. The observed loss was alleviated by changing the methanol (MeOH) concentration in the final solvent. The required MeOH concentration varied depending on which congener was present. Microcystins only adsorbed to glass pipettes (loss up to 30% after eight pipet actions) when in acidified aqueous solutions. The latter appeared largely dependent on the presence of ionizable groups, such as arginine residues.

Use of lead-glazed ceramic ware and lead-based folk remedies in a rural community of Baja California, Mexico.

PubMed

Welton, Michael; Rodriguez-Lainz, Alfonso; Loza, Oralia; Brodine, Stephanie; Fraga, Miguel

2018-03-01

Lead exposure from lead-glazed ceramics (LGCs) and traditional folk remedies have been identified as significant sources of elevated blood lead levels in Mexico and the United States. This study took place from 2005 to 2012 in a rural community in Baja California, Mexico. 1) Investigate the knowledge, attitudes, and practices related to lead and lead exposures from LGCs and two lead-based folk remedies ( azarcon and greta); and 2) evaluate a pilot intervention to provide alternative lead-safe cookware. A baseline household survey was conducted in 2005, followed by the pilot intervention in 2006, and follow-up surveys in 2007 and 2012. For the pilot intervention, families who reported using LGCs were given lead-safe alternative cookware to try and its acceptance was evaluated in the following year. The community was mostly of indigenous background from Oaxaca and a high proportion of households had young children. In 2006, all participants using traditional ceramic ware at the time ( n = 48) accepted lead-safe alternative cookware to try, and 97% reported that they were willing to exchange traditional ceramic ware for lead-safe alternatives. The use of ceramic cookware decreased from over 90% during respondents' childhood household use in Oaxaca to 47% in 2006 among households in Baja California, and further reduced to 16.8% in 2012. While empacho, a folk illness, was widely recognized as an intestinal disorder, there was almost universal unfamiliarity with the use and knowledge of azarcon and greta for its treatment. This pilot evaluation provides evidence 1) for an effective and innovative strategy to reduce lead exposure from LGCs and 2) of the feasibility of substituting lead-free alternative cookware for traditional ceramic ware in a rural indigenous community, when delivered in a culturally appropriate manner with health education. This strategy could complement other approaches to reduce exposure to lead from LGCs.

Left thoracotomy HeartWare implantation with outflow graft anastomosis to the descending aorta: a simplified bridge for patients with multiple previous sternotomies.

PubMed

Umakanthan, Ramanan; Haglund, Nicholas A; Stulak, John M; Joyce, Lyle D; Ahmad, Rashid; Keebler, Mary E; Maltais, Simon

2013-01-01

Advances in mechanical circulatory support have been critical in bridging patients awaiting heart transplantation. In addition, improvement in device durability has enabled left ventricular assist device therapy to be applied as destination therapy in those not felt to be transplant candidate. Because of the increasing complexity of patients, there continues to be a need for alternative strategies for device implantation to bridge high-risk patients awaiting heart transplantation, wherein the risks of numerous previous sternotomies may be prohibitive. We present a unique technique for placement of the HeartWare ventricular assist device via left anterior thoracotomy to the descending aorta in a patient awaiting heart transplantation with a history of multiple previous sternotomies.

Roman mosaic glass: a study of production processes, using PIXE spectrometry

NASA Astrophysics Data System (ADS)

Fleming, S. J.; Swann, C. P.

1999-04-01

The most attractive Roman glass produced during the early part of the 1st century A.D. was mosaic ware - bowls and dishes molded from arrays of multi-colored canes that created abstract floral and geometric designs. Yet ancient literature tells us little about the organization of the glassworking industry in which such wares were produced. We have focused upon two kinds of mosaic decoration that include a component of white glass in their cane construction and have purple glass as their matrix. A consistent pattern in the minor levels of lead in each kind of glass suggests that they were the products of two separate workshops, each with separate sources of supply for their glass stock.

Low-cost real-time 3D PC distributed-interactive-simulation (DIS) application for C4I

NASA Astrophysics Data System (ADS)

Gonthier, David L.; Veron, Harry

1998-04-01

A 3D Distributed Interactive Simulation (DIS) application was developed and demonstrated in a PC environment. The application is capable of running in the stealth mode or as a player which includes battlefield simulations, such as ModSAF. PCs can be clustered together, but not necessarily collocated, to run a simulation or training exercise on their own. A 3D perspective view of the battlefield is displayed that includes terrain, trees, buildings and other objects supported by the DIS application. Screen update rates of 15 to 20 frames per second have been achieved with fully lit and textured scenes thus providing high quality and fast graphics. A complete PC system can be configured for under $2,500. The software runs under Windows95 and WindowsNT. It is written in C++ and uses a commercial API called RenderWare for 3D rendering. The software uses Microsoft Foundation classes and Microsoft DirectPlay for joystick input. The RenderWare libraries enhance the performance through optimization for MMX and the Pentium Pro processor. The RenderWare and the Righteous 3D graphics board from Orchid Technologies with an advertised rendering rate of up to 2 million texture mapped triangles per second. A low-cost PC DIS simulator that can partake in a real-time collaborative simulation with other platforms is thus achieved.

Adsorption of Ten Microcystin Congeners to Common Laboratory-Ware Is Solvent and Surface Dependent

PubMed Central

Altaner, Stefan; Puddick, Jonathan; Wood, Susanna A.; Dietrich, Daniel R.

2017-01-01

Cyanobacteria can produce heptapetides called microcystins (MC) which are harmful to humans due to their ability to inhibit cellular protein phosphatases. Quantitation of these toxins can be hampered by their adsorption to common laboratory-ware during sample processing and analysis. Because of their structural diversity (>100 congeners) and different physico-chemical properties, they vary in their adsorption to surfaces. In this study, the adsorption of ten different MC congeners (encompassing non-arginated to doubly-arginated congeners) to common laboratory-ware was assessed using different solvent combinations. Sample handling steps were mimicked with glass and polypropylene pipettes and vials with increasing methanol concentrations at two pH levels, before analysis by liquid chromatography-tandem mass spectrometry. We demonstrated that MC adsorb to polypropylene surfaces irrespective of pH. After eight successive pipet actions using polypropylene tips ca. 20% of the MC were lost to the surface material, which increased to 25%–40% when solutions were acidified. The observed loss was alleviated by changing the methanol (MeOH) concentration in the final solvent. The required MeOH concentration varied depending on which congener was present. Microcystins only adsorbed to glass pipettes (loss up to 30% after eight pipet actions) when in acidified aqueous solutions. The latter appeared largely dependent on the presence of ionizable groups, such as arginine residues. PMID:28383495

Early Feasibility Testing and Engineering Development of the Transapical Approach for the HeartWare MVAD Ventricular Assist System

PubMed Central

Tamez, Daniel; LaRose, Jeffrey A.; Shambaugh, Charles; Chorpenning, Katherine; Soucy, Kevin G; Sobieski, Michael A; Sherwood, Leslie; Giridharan, Guruprasad A; Monreal, Gretel; Koenig, Steven C; Slaughter, Mark S

2014-01-01

Implantation of ventricular assist devices (VADs) for treatment of end-stage heart failure (HF) falls decidedly short of clinical demand, which exceeds 100,000 HF patients per year. VAD implantation often requires major surgical intervention with associated risk of adverse events and long recovery periods. To address these limitations, HeartWare, Inc. (Miami Lakes, FL) has developed a platform of miniature ventricular devices with progressively reduced surgical invasiveness and innovative patient peripherals. One surgical implant concept is a transapical version of the miniaturized left ventricular assist device (MVAD). The HeartWare MVAD Pump® is a small, continuous flow, full-support device that has a displacement volume of 22mL. A new cannula configuration has been developed for transapical implantation, where the outflow cannula is positioned across the aortic valve. The two primary objectives for this feasibility study were to evaluate anatomic fit and surgical approach and efficacy of the transapical MVAD configuration. Anatomic fit and surgical approach were demonstrated using human cadavers (n=4). Efficacy was demonstrated in acute (n =2) and chronic (n = 1) bovine model experiments and assessed by improvements in hemodynamics, biocompatibility, flow dynamics, and histopathology. Potential advantages of the MVAD Pump include flow support in the same direction as the native ventricle, elimination of cardiopulmonary bypass, and minimally-invasive implantation. PMID:24399057

Microstructure and properties of ceramics

NASA Technical Reports Server (NTRS)

Hamano, K.

1984-01-01

The history of research into the microstructure and properties of ceramic ware is discussed; methods of producing ceramics with particular characteristics are investigated. Bubbles, sintering, cracks, and electron microscopy are discussed.

Anne Elizabeth Ware | NREL

Science.gov Websites

Accumulation in Leaves of Sorghum bicolor (L.) Moench: A Source of Natural Food Pigment," J. Agricultural and Food Chemistry (2014) "Catalytic deoxygenation of triglycerides and fatty acids to

Applied analysis of lacquer films based on pyrolysis-gas chromatography/mass spectrometry.

PubMed

Lu, Rong; Kamiya, Yukio; Miyakoshi, Tetsuo

2006-09-15

Ancient lacquer film, a Nanban lacquer film, an old lacquer-ware object imported from an Asian country, and the Baroque and Rococo lacquer films were analyzed by pyrolysis-gas chromatography/mass spectrometry. Compared with the results of the natural lacquer film, it was revealed that the ancient lacquer film and Nanban lacquer film were made from Rhus vernicifera, and the old lacquer-ware imported from an Asian country was made from Melanorrhoea usitata. However, the Baroque and Rococo lacquer films obtained from the Doerner Institute in Munich, Germany were made from natural resins. 3-Pentadecylcatechol (MW=320) (urushiol), 3-heptadecylcatechol (MW=348) (laccol), and 4-heptadecylcatechol (MW=348) (thitsiol) were the main products of the pyrolysis of R. vernicifera, Rhus succedanea, and M. usitata.

Left Thoracotomy HeartWare Implantation With Outflow Graft Anastomosis to the Descending Aorta: A Simplified Bridge for Patients With Multiple Previous Sternotomies

PubMed Central

Umakanthan, Ramanan; Haglund, Nicholas A.; Stulak, John M.; Joyce, Lyle D.; Ahmad, Rashid; Keebler, Mary E.; Maltais, Simon

2014-01-01

Advances in mechanical circulatory support have been critical in bridging patients awaiting heart transplantation. In addition, improvement in device durability has enabled left ventricular assist device therapy to be applied as destination therapy in those not felt to be transplant candidate. Because of the increasing complexity of patients, there continues to be a need for alternative strategies for device implantation to bridge high-risk patients awaiting heart transplantation, wherein the risks of numerous previous sternotomies may be prohibitive. We present a unique technique for placement of the HeartWare ventricular assist device via left anterior thoracotomy to the descending aorta in a patient awaiting heart transplantation with a history of multiple previous sternotomies. PMID:24172273

29 CFR 784.14 - “Goods.”

Code of Federal Regulations, 2011 CFR

2011-07-01

... FISHING AND OPERATIONS ON AQUATIC PRODUCTS General Some Basic Definitions § 784.14 “Goods.” The definition... marine equipment), wares, products, commodities, merchandise, or articles or subjects of commerce of any...

29 CFR 784.14 - “Goods.”

Code of Federal Regulations, 2010 CFR

2010-07-01

... FISHING AND OPERATIONS ON AQUATIC PRODUCTS General Some Basic Definitions § 784.14 “Goods.” The definition... marine equipment), wares, products, commodities, merchandise, or articles or subjects of commerce of any...

Back table outflow graft anastomosis technique for HeartWare HVAD implantation.

PubMed

Basher, S; Bick, J; Maltais, S

2015-12-01

The management of concomitant aortic and aortic valve disease with left ventricular assist device (LVAD) implantation for patients with severe cardiomyopathy is challenging, and has not been established given the complexity of LVAD surgery with concomitant aortic interventions. A 45-year-old patient presented to our institution with end-stage heart failure symptoms and non-ischemic cardiomyopathy. The patient was found to have a bicuspid aortic valve, severe native aortic regurgitation, a significant ascending aortic aneurysm, and severely depressed left ventricular (LV) function requiring two inotropes. He underwent a successful hemiarch repair of the ascending aortic aneurysm using a back table outflow graft anastomosis technique, and subsequent placement of a HeartWare Ventricular Assist Device (HVAD) with concomitant aortic valve closure with a modified Park's stitch. The patient did well postoperatively and is currently listed for heart transplantation.

[Aluminum--occurrence and toxicity for organisms].

PubMed

Ochmański, W; Barabasz, W

2000-01-01

Aluminium (Al.) is an ubiquitous element found in every food product. The sources of Al. are especially corn, yellow cheese, salt, herbs, spices, tea and tap water. In household Al.-made ware is a major source of the element. Al. may cause diseases in humans, especially hampers many metabolic processes especially turnover of calcium, phosphorus and iron. Salts of Al. may bind to DNA, RNA, inhibit such enzymes as hexokinase, acid and alkaline phosphatases, phosphodiesterase and phosphooxydase. Al. salts are especially harmful to nervous, hematopoietic systems and to skeleton. Al. gets to organism with food, water, cosmetics, from aluminium ware and containers. Toxicity comes from substitution of Mg and Fe ions effecting in disturbances in intracellular signaling, excretory functions and cellular growth. Neurotoxic action of Al. probably comes from substitution of Mg ions in ATP, what finally influences function of every ATP using-enzymes. There are observations in experimental models proving Al. salts are responsible for Alzheimer disease development. Toxicity of Al. to skeletal system results in diminished resistance thus tendencies to breaking, and comes from lower collagen synthesis and slowing down of mineralisation. Low erythropoietin production, inhibition of hem-synthesing enzymes and binding of Al. to transferrin, effects in anaemia. Carcinogenic effects of Al. were nor proved nor denied, but high concentrations of Al. were found in many neoplastic cells. In conclusion, we should introduce prophylactic measures effecting in less Al. intake esp. avoiding use of Al.-made ware nad controlling food for Al. content.

1. Historic American Buildings Survey E. W. Russell, Photographer, March ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey E. W. Russell, Photographer, March 14, 1936 REAR VIEW, NORTH OF SLAVE QUARTERS - Waring House, Slave Quarters, 351 Government Street (now South Claiborne Street), Mobile, Mobile County, AL

38 CFR 3.810 - Clothing allowance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... wears or uses certain prosthetic or orthopedic appliances which tend to wear or tear clothing (including... or used which tends to ware or tear the veteran's clothing, or that because of the use of a physician...

Worldwide Report, Arms Control

DTIC Science & Technology

1985-09-21

Intersoft- ware, Logic Control Control y Aplicaciones , Dielsa, Eliop, EISA, Sainco CTNE, Fagor Electronica, Standard CTNE, Fagor Electronica, Piher...regulation systems Industrial turbine of advanced design Alfa Sewing Machines Control y Aplicaciones , Danobat, Etxe-Tar C02, CO and ultraviolet lasers

Comparison of methods for measuring travel time at Florida freeways and arterials : [summary].

DOT National Transportation Integrated Search

2014-07-01

In this project, University of Florida researchers : collected field data along several highways to : evaluate travel time measurements from several : sources: STEWARD, BlueTOAD, INRIX, and HERE. : STEWARD (Statewide Transportation Engineering : Ware...

40 CFR 63.11440 - What are the monitoring requirements for new and existing sources?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Clay Ceramics Manufacturing Area Sources Standards, Compliance, and Monitoring Requirements § 63.11440... ceramic ware, you must conduct a daily check of the peak firing temperature. If the peak temperature...

Knowledge Retrieval Solutions.

ERIC Educational Resources Information Center

Khan, Kamran

1998-01-01

Excalibur RetrievalWare offers true knowledge retrieval solutions. Its fundamental technologies, Adaptive Pattern Recognition Processing and Semantic Networks, have capabilities for knowledge discovery and knowledge management of full-text, structured and visual information. The software delivers a combination of accuracy, extensibility,…

47 CFR 90.614 - Segments of the 806-824/851-869 MHz band for non-border areas.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., Jasper, Jeff Davis, Jefferson, Jenkins, Johnson, Jones, Lamar, Lanier, Laurens, Lee, Liberty, Lincoln..., Thomas, Tift, Toombs, Towns, Treutlen, Troup, Turner, Twiggs, Union, Upson, Walker, Walton, Ware, Warren...

47 CFR 90.614 - Segments of the 806-824/851-869 MHz band for non-border areas.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., Jasper, Jeff Davis, Jefferson, Jenkins, Johnson, Jones, Lamar, Lanier, Laurens, Lee, Liberty, Lincoln..., Thomas, Tift, Toombs, Towns, Treutlen, Troup, Turner, Twiggs, Union, Upson, Walker, Walton, Ware, Warren...

47 CFR 90.614 - Segments of the 806-824/851-869 MHz band for non-border areas.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., Jasper, Jeff Davis, Jefferson, Jenkins, Johnson, Jones, Lamar, Lanier, Laurens, Lee, Liberty, Lincoln..., Thomas, Tift, Toombs, Towns, Treutlen, Troup, Turner, Twiggs, Union, Upson, Walker, Walton, Ware, Warren...

Assessing the goodness-of-fit of the Laird and Ware model--an example: the Jimma Infant Survival Differential Longitudinal Study.

PubMed

Lesaffre, E; Asefa, M; Verbeke, G

1999-04-15

The Jimma Infant Survival Differential Longitudinal Study is an Ethiopian study, set up to establish risk factors affecting infant survival and to investigate socio-economic, maternal and infant-rearing factors that contribute most to the child's early survival. Here, a subgroup of about 1500 children born in Jimma town is examined for their first year's weight gain. Of special interest is the impact of certain cultural practices like uvulectomy, milk teeth extraction and butter swallowing, on child's weight gain; these have never been thoroughly investigated in any study. In this context, the linear mixed model (Laird and Ware) is employed. The purpose of this paper is to illustrate the practical issues when constructing the longitudinal model. Recently developed diagnostics will be used herefor. Finally, special attention will be paid to the two-stage interpretation of the linear mixed model.

Recent applications of PIXE spectrometry in archaeology II. Characterization of Chinese pottery exported to the Islamic world

NASA Astrophysics Data System (ADS)

Fleming, S. J.; Swann, C. P.

1992-02-01

The early 9th century A.D. trade links between China's Tang dynasty and the Western world, by land along the caravan routes of the Silk Road and by sea via India and the Gulf, encouraged a taste for many kinds of Chinese ceramics among the affluent societies of the Islamic empire. Using PIXE analysis to determine the primary composition and minor element patterns of the clay fabrics of a wide range of pottery recovered from the Islamic city of Siraf (in southern Iran), we have established clear differences between Chinese wares imported to that region and a variety of imitative wares of local origin. Parallels and contrasts are drawn between our data and those obtained by Chinese scholars in recent years for the products of various Tang kiln sites, particularly for a series of distinctive stonewares from Tongguan (Hunan province).

Heat Generation in Axial and Centrifugal Flow Left Ventricular Assist Devices.

PubMed

Yost, Gardner; Joseph, Christine Rachel; Royston, Thomas; Tatooles, Antone; Bhat, Geetha

Despite increasing use of left ventricular assist devices (LVADs) as a surgical treatment for advanced heart failure in an era of improved outcomes with LVAD support, the mechanical interactions between these pumps and the cardiovascular system are not completely understood. We utilized an in vitro mock circulatory loop to analyze the heat production incurred by operation of an axial flow and centrifugal flow LVAD. A HeartMate II and a HeartWare HVAD were connected to an abbreviated flow loop and were implanted in a viscoelastic gel. Temperature was measured at the surface of each LVAD. Device speed and fluid viscosity were altered and, in the HeartMate II, as artificial thrombi were attached to the inflow stator, impeller, and outflow stator. The surface temperatures of both LVADs increased in all trials and reached a plateau within 80 minutes of flow initiation. Rate of heat generation and maximum system temperature were greater when speed was increased, when viscosity was increased, and when artificial thrombi were attached to the HeartMate II impeller. Normal operation of these two widely utilized LVADs results in appreciable heat generation in vitro. Increased pump loading resulted in more rapid heat generation, which was particularly severe when a large thrombus was attached to the impeller of the HeartMate II. While heat accumulation in vivo is likely minimized by greater dissipation in the blood and soft tissues, focal temperature gains with the pump housing of these two devices during long-term operation may have negative hematological consequences.

76 FR 64102 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-17

... District, Roughly bounded by S. Philpot St., East Ave, E. Ware & Park Sts., Cedartown, 11000776 IDAHO Ada... following resource: MAINE Androscoggin County Cowan Mill Island Mill St., Lewiston, 85001656 [FR Doc. 2011...

A Survey of Fuel and Energy Information Sources: Volume II

EPA Pesticide Factsheets

... con"",,, alld r~~i~~1' ,rl~'~~~i!~S' than who.ld Tau! ... I'ART of the year, plenoc fill out thio form. ... effect and na'ure of any impor- \\ant ware acale chanl ...

Real-Time High-Dynamic Range Texture Mapping

DTIC Science & Technology

2001-01-01

the renderings produced by radiosity and global illumination algorithms. As a particular example, Greg Ward’s RADIANCE synthetic imaging system [32...in soft- ware only. [26] presented a technique for performing Ward’s tone reproduction algo- rithm interactively to visualize radiosity solutions

The development of the time-keeping clock with TS-1 single chip microcomputer.

NASA Astrophysics Data System (ADS)

Zhou, Jiguang; Li, Yongan

The authors have developed a time-keeping clock with Intel 8751 single chip microcomputer that has been successfully used in time-keeping station. The hard-soft ware design and performance of the clock are introduced.

JPRS Report, China.

DTIC Science & Technology

1993-06-08

size, with some of its industrial wares entering international markets. Overall, however, because of the shortage of capital and some irrational ...time. Japan’s exuberance makes it a formidable adversary of the United States and the USSR in the scientific and high technology fields. The grim

Upper Blackstone Water Pollution Abatement District Chief Operator Recognized for Outstanding Service

EPA Pesticide Factsheets

Joseph Nowak, a resident of Ware Mass. and Chief Operator of the Upper Blackstone Water Pollution Abatement District (District) in Milbury, Mass., was honored by EPA with a 2016 Regional Wastewater Treatment Plant Operator of the Year Excellence Award.

Rewards for Good Marketing

ERIC Educational Resources Information Center

Germain, Carol Anne, Ed.

2009-01-01

Many professional library associations and affiliates "strongly encourage" the marketing of libraries and their wares. These organizations present awards, certificates, and monetary enticements to honor outstanding marketing programs. For most individuals or teams who are already working on and implementing marketing programs, the added effort of…

Coating method for graphite

DOEpatents

Banker, John G.; Holcombe, Jr., Cressie E.

1977-01-01

A method of limiting carbon contamination from graphite ware used in induction melting of uranium alloys is provided comprising coating the graphite surface with a suspension of Y.sub.2 O.sub.3 particles in water containing about 1.5 to 4% by weight sodium carboxymethylcellulose.

Coating method for graphite

DOEpatents

Banker, J.G.; Holcombe, C.E. Jr.

1975-11-06

A method of limiting carbon contamination from graphite ware used in induction melting of uranium alloys is provided. The graphite surface is coated with a suspension of Y/sub 2/O/sub 3/ particles in water containing about 1.5 to 4 percent by weight sodium carboxymethylcellulose.

Marine Debris and Plastic Source Reduction Toolkit

EPA Pesticide Factsheets

Many plastic food service ware items originate on college and university campuses—in cafeterias, snack rooms, cafés, and eateries with take-out dining options. This Campus Toolkit is a detailed “how to” guide for reducing plastic waste on college campuses.

Categorical regression dose-response modeling

EPA Science Inventory

The goal of this training is to provide participants with training on the use of the U.S. EPA’s Categorical Regression soft¬ware (CatReg) and its application to risk assessment. Categorical regression fits mathematical models to toxicity data that have been assigned ord...

Featured Molecules: Sucrose and Vanillin

NASA Astrophysics Data System (ADS)

Coleman, William F.; Wildman, Randall J.

2003-04-01

The WebWare molecules of the month for April relate to the sense of taste. Apple Fool, the JCE Classroom Activity, mentions sucrose and vanillin and their use as flavorings. Fully manipulable (Chime) versions of these and other molecules are available at Only@JCE Online.

Compositional data supports decentralized model of production and circulation of artifacts in the pre-Columbian south-central Andes.

PubMed

Lazzari, Marisa; Pereyra Domingorena, Lucas; Stoner, Wesley D; Scattolin, María Cristina; Korstanje, María Alejandra; Glascock, Michael D

2017-05-16

The circulation and exchange of goods and resources at various scales have long been considered central to the understanding of complex societies, and the Andes have provided a fertile ground for investigating this process. However, long-standing archaeological emphasis on typological analysis, although helpful to hypothesize the direction of contacts, has left important aspects of ancient exchange open to speculation. To improve understanding of ancient exchange practices and their potential role in structuring alliances, we examine material exchanges in northwest Argentina (part of the south-central Andes) during 400 BC to AD 1000 (part of the regional Formative Period), with a multianalytical approach (petrography, instrumental neutron activation analysis, laser ablation inductively coupled plasma mass spectrometry) to artifacts previously studied separately. We assess the standard centralized model of interaction vs. a decentralized model through the largest provenance database available to date in the region. The results show: ( i ) intervalley heterogeneity of clays and fabrics for ordinary wares; ( ii ) intervalley homogeneity of clays and fabrics for a wide range of decorated wares (e.g., painted Ciénaga); ( iii ) selective circulation of two distinct polychrome wares (Vaquerías and Condorhuasi); ( iv ) generalized access to obsidian from one major source and various minor sources; and ( v ) selective circulation of volcanic rock tools from a single source. These trends reflect the multiple and conflicting demands experienced by people in small-scale societies, which may be difficult to capitalize by aspiring elites. The study undermines centralized narratives of exchange for this period, offering a new platform for understanding ancient exchange based on actual material transfers, both in the Andes and beyond.

Compositional data supports decentralized model of production and circulation of artifacts in the pre-Columbian south-central Andes

PubMed Central

Pereyra Domingorena, Lucas; Stoner, Wesley D.; Scattolin, María Cristina; Korstanje, María Alejandra; Glascock, Michael D.

2017-01-01

The circulation and exchange of goods and resources at various scales have long been considered central to the understanding of complex societies, and the Andes have provided a fertile ground for investigating this process. However, long-standing archaeological emphasis on typological analysis, although helpful to hypothesize the direction of contacts, has left important aspects of ancient exchange open to speculation. To improve understanding of ancient exchange practices and their potential role in structuring alliances, we examine material exchanges in northwest Argentina (part of the south-central Andes) during 400 BC to AD 1000 (part of the regional Formative Period), with a multianalytical approach (petrography, instrumental neutron activation analysis, laser ablation inductively coupled plasma mass spectrometry) to artifacts previously studied separately. We assess the standard centralized model of interaction vs. a decentralized model through the largest provenance database available to date in the region. The results show: (i) intervalley heterogeneity of clays and fabrics for ordinary wares; (ii) intervalley homogeneity of clays and fabrics for a wide range of decorated wares (e.g., painted Ciénaga); (iii) selective circulation of two distinct polychrome wares (Vaquerías and Condorhuasi); (iv) generalized access to obsidian from one major source and various minor sources; and (v) selective circulation of volcanic rock tools from a single source. These trends reflect the multiple and conflicting demands experienced by people in small-scale societies, which may be difficult to capitalize by aspiring elites. The study undermines centralized narratives of exchange for this period, offering a new platform for understanding ancient exchange based on actual material transfers, both in the Andes and beyond. PMID:28461485

Examining the Role of Metadata in Testing IED Detection Systems

DTIC Science & Technology

2009-09-01

energy management, crop assessment, weather forecasting, disaster alerts, and endangered species assessment [ Biagioni and Bridges 2002; Main- waring et...accessed June 10, 2008). Biagioni , E. and K. Bridges. 2002. The application of remote sensor technology to assist the recovery of rare endangered species

Long-Term Storage Studies on Dehydrated Ration Items and Food Packets

DTIC Science & Technology

1976-06-01

and onions, bacon, corn, fruit salad, steamed fruitcake, chocolate nut bread, plums, rolled oats, raspberry and strawberry Jams , and one brand of... strawberry jam , biscuit spread, and canned peachsa ware unacceptable; scores for chocolate bera, beef and apaghetti, chicksn soup, canned plums

Research on corrosion mechanism of suspension insulator steel foot of direct current system and measures for corrosion inhibition

NASA Astrophysics Data System (ADS)

Chen, He; Yang, Yueguang; Su, Guolei; Wang, Xiaoqing; Zhang, Hourong; Sun, Xiaoyu; Fan, Youping

2017-09-01

There are increasingly serious electrocorrosion phenomena on insulator hardware caused by direct current transmission due to the wide-range popularization of extra high voltage direct current transmission engineering in our country. Steel foot corrosion is the main corrosion for insulators on positive polarity side of transmission lines. On one hand, the corrosion leads to the tapering off of steel foot diameter, having a direct influence on mechanical property of insulators; on the other hand, in condition of corrosion on steel foot wrapped in porcelain ware, the volume of the corrosion product is at least 50% more than that of the original steel foot, leading to bursting of porcelain ware, threatening safe operation of transmission lines. Therefore, it is necessary to conduct research on the phenomenon and propose feasible measures for corrosion inhibition. Starting with the corrosion mechanism, this article proposes two measures for corrosion inhibition, and verifies the inhibition effect in laboratory conditions, providing reference for application in engineering.

Original Courseware for Introductory Psychology: Implementation and Evaluation.

ERIC Educational Resources Information Center

Slotnick, Robert S.

1988-01-01

Describes the implementation and field testing of PsychWare, a courseware package for introductory psychology developed and field tested at New York Institute of Technology. Highlights include the courseware package (10 software programs, a faculty manual, and a student workbook), and instructional design features (simulations, real-time…

Language Development and Scaffolding in a Sino-American Telecollaborative Project

ERIC Educational Resources Information Center

Jin, Li

2013-01-01

Previous research (e.g., Belz & Thorne, 2006; Ware & O'Dowd, 2008) has discovered that language learning can be afforded through intercultural telecollaboration. From a sociocultural theoretical perspective, the current study investigated the language development outcomes and process in a 10-week Sino-American telecollaborative project…

33 CFR 101.105 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... without containers or labels, and that is received and handled without mark or count. Bunkers means a..., part A. Cargo means any goods, wares, or merchandise carried, or to be carried, for consideration... interested in the vessel, facility, or OCS facility, except dredge spoils. Cargo vessel means a vessel that...

33 CFR 101.105 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... without containers or labels, and that is received and handled without mark or count. Bunkers means a..., part A. Cargo means any goods, wares, or merchandise carried, or to be carried, for consideration... interested in the vessel, facility, or OCS facility, except dredge spoils. Cargo vessel means a vessel that...

33 CFR 101.105 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... without containers or labels, and that is received and handled without mark or count. Bunkers means a..., part A. Cargo means any goods, wares, or merchandise carried, or to be carried, for consideration... interested in the vessel, facility, or OCS facility, except dredge spoils. Cargo vessel means a vessel that...

33 CFR 101.105 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... without containers or labels, and that is received and handled without mark or count. Bunkers means a..., part A. Cargo means any goods, wares, or merchandise carried, or to be carried, for consideration... interested in the vessel, facility, or OCS facility, except dredge spoils. Cargo vessel means a vessel that...

Traditional Chinese medicine Guizhi Fuling capsule used for therapy of dysmenorrhea via attenuating uterus contraction.

PubMed

Sun, Lan; Liu, Lina; Zong, Shaobo; Wang, Zhengzhong; Zhou, Jun; Xu, Zhiliang; Ding, Gang; Xiao, Wei; Kou, Junping

2016-09-15

Guizhi Fuling formula, a well-known Chinese herbal formula recorded in the Eastern Han Dynasty, is composed of Cinnamomum cassia (L.) J.Presl (Cassia bark), Poria cocos (Schw.) Wolf (Poria), Paeonia suffruticosa andrews (Moutan Cortex), Paeonia lactiflora Pall (Herbaceous peony), and Amygdalus persica L.(Persicae Semen). It has clinical efficacy of activating blood circulation to dissipate blood stasis and is commonly used for the treatment of primary dysmenorrhea. However, its therapeutic mechanism has not been clearly elucidated. The aim of this study is to reveal molecular mechanisms of action using in vivo and in vitro experimental models. The ICR mouse uterine contraction was induced by oxytocin exposure following estradiol benzoate pretreatment. Mice were given GZFLC (0.54, 1.08g/kg) by gavage. The levels of NO, PGF2α and Ca(2+) in uterine tissue were determined according to instructions. Cyclooxygenase-2 (COX-2) and oxytocin receptor (OTR) proteins in uterine tissue were assessed by Western Blot. Mouse isolated uterus strips were mounted in tissue organ baths containing Locke's solution. The contractile responses were recorded with Power Lab recording system. The effect of GZFLC on spontaneous uterine contraction, and uterine contraction induced by oxytocin, PGF2α was observed. Myometrial cells were exposed to oxytocin (5U/L) to induce calcium release, and the effect of GZFLC and its components (PL, PGG, CA) on intracellular Ca(2+) was analyzed with fluorometry imaging. In vivo study demonstrated that GZFLC significantly reduced oxytocin-induced writhing responses with a maximal inhibition of 55%. It also decreased the levels of NO, PGF2α and Ca(2+) in oxytocin-induced mice uterine tissue. Moreover, Western blot analysis showed that COX-2 and OTR expressions in uterine tissue of dysmenorrhea mice were significantly reduced. GZFLC inhibited spontaneous uterus contractions in a dose-dependent manner, and the IC50 value was 0.99mg/ml. The IC50 values of GZFLC on PGF2α, oxytocin-induced contractions were 1.45mg/ml, 3.53mg/ml, respectively. Further in vitro studies indicated that GZFLC and its components (PL, PGG, CA) could restrain intracellular calcium levels in favour of uteri relaxation. Both in vivo and in vitro results indicated that GZFLC possessed a significant spasmolytic effect on uterine tetanic contraction. The present study provides in vivo and in vitro experimental evidence to support the use of GZFLC for the clinical treatment of primary dysmenorrheal (PD). Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Computer Tutors Get Personal

ERIC Educational Resources Information Center

Johnson, David L.

2005-01-01

After decades of research in artificial intelligence (AI) and cognitive psychology, a number of companies have emerged that offer intelligent tutor system (ITS) soft ware to schools. These systems try to mimic the help that a human tutor would provide to an individual student, something nearly impossible for teachers to accomplish in the…

MOOCs, High Technology, and Higher Learning

ERIC Educational Resources Information Center

Rhoads, Robert A.

2015-01-01

In "MOOCs, High Technology, and Higher Learning," Robert A. Rhoads places the OpenCourseWare (OCW) movement into the larger context of a revolution in educational technology. In doing so, he seeks to bring greater balance to increasingly polarized discussions of massively open online courses (MOOCs) and show their ongoing relevance to…

26 CFR 301.7304-1 - Penalty for fraudulently claiming drawback.

Code of Federal Regulations, 2010 CFR

2010-04-01

... drawback on goods, wares, or merchandise on which no internal tax shall have been paid, or fraudulently claims any greater allowance of drawback than the tax actually paid, he shall forfeit triple the amount....7304-1 Section 301.7304-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY...

Developing Intercultural Communicative Competence through Online Exchanges

ERIC Educational Resources Information Center

Chun, Dorothy M.

2011-01-01

Based on Byram's (1997) definition of intercultural communicative competence (ICC) and on specific types of discourse analysis proposed by Kramsch and Thorne (2002) and Ware and Kramsch (2005), this article explores how online exchanges can play a role in second language learners' development of pragmatic competence and ICC. With data obtained…

Analysis of Learning Achievement and Teacher-Student Interactions in Flipped and Conventional Classrooms

ERIC Educational Resources Information Center

Sun, Jerry Chih-Yuan; Wu, Yu-Ting

2016-01-01

This study aimed to investigate the effectiveness of two different teaching methods on learning effectiveness. OpenCourseWare was integrated into the flipped classroom model (experimental group) and distance learning (control group). Learning effectiveness encompassed learning achievement, teacher-student interactions, and learning satisfaction.…

7 CFR 2902.52 - Disposable tableware.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 15 2011-01-01 2011-01-01 false Disposable tableware. 2902.52 Section 2902.52 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF ENERGY POLICY AND NEW USES... and used in dining, such as drink ware and dishware, including but not limited to cups, plates, bowls...

Contributory Factors to Teachers' Sense of Community in Public Urban Elementary Schools

ERIC Educational Resources Information Center

Kirkhus, Debra

2011-01-01

The purpose of this study was to investigate factors that contribute to teachers' sense of community within public, urban, elementary schools. Because previous research has touted the benefits of teacher communities within schools (Kruse, 2001; Leana & Pil, 2006; Ware & Kitsantas, 2007) educational leaders are challenged with creating…

The Hard(ware) Choice

ERIC Educational Resources Information Center

Demski, Jennifer

2012-01-01

When it comes to implementing a large-scale 1-to-1 computing initiative, deciding which device students will use every day to support their learning requires a significant amount of thought and research. Laptop, netbook, Chromebook, tablet--each device has enough similarities to make the decision seem easy, but enough differences to make a big…

40 CFR 63.11436 - What parts of my plant does this subpart cover?

Code of Federal Regulations, 2010 CFR

2010-07-01

... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Clay Ceramics... subpart cover? (a) This subpart applies to any existing or new affected source located at a clay ceramics... glazed ceramic ware located at a clay ceramics manufacturing facility. (c) An affected source is existing...

40 CFR 63.11441 - What are the notification requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Clay Ceramics Manufacturing Area... glazed ceramic ware, you must certify that you are maintaining the peak temperature below 1540 °C (2800... ceramics manufacturing facility that uses more than 227 Mg/yr (250 tpy) of wet glaze(s), you must certify...

40 CFR 63.11435 - Am I subject to this subpart?

Code of Federal Regulations, 2010 CFR

2010-07-01

...) National Emission Standards for Hazardous Air Pollutants for Clay Ceramics Manufacturing Area Sources... if you own or operate a clay ceramics manufacturing facility (as defined in § 63.11444), with an atomized glaze spray booth or kiln that fires glazed ceramic ware, that processes more than 45 megagrams...

Using Simulation Module, PCLAB, for Steady State Disturbance Sensitivity Analysis in Process Control

ERIC Educational Resources Information Center

Ali, Emad; Idriss, Arimiyawo

2009-01-01

Recently, chemical engineering education moves towards utilizing simulation soft wares to enhance the learning process especially in the field of process control. These training simulators provide interactive learning through visualization and practicing which will bridge the gap between the theoretical abstraction of textbooks and the…

Parents' Perception on De La Salle University-Dasmarinas Services

ERIC Educational Resources Information Center

Cortez-Antig, Carmelyn

2011-01-01

The study was conducted to find out the parents' perception on the De La Salle University-Dasmarinas services which are grouped as follows: (1) Academic instruction factor; (2) Quality of human ware (includes faculty, administration, staff support through medical services, guidance and discipline); (3) Quality of hardware (dorm facilities,…

Marketing: Giveaways that Give Back--Marketing with Promotional Items

ERIC Educational Resources Information Center

Germain, Carol Anne

2006-01-01

In marketing one's library wares, an effective publicity strategy is to use promotional giveaway materials, mainly personalized items that promote one's resources and services. As with any marketing effort, it is important to be clear about the promotional initiative and whom librarians are attempting to reach. This author emphasizes that…

Pressures on TV Programs: Coalition for Better Television's Case.

ERIC Educational Resources Information Center

Shipman, John M., Jr.

In 1981, the conservative Coalition for Better Television (CBTV) threatened an economic boycott against advertisers who marketed their wares on programs that the coalition felt had excessive sex and violence. Because television networks are dependent on advertising, the coalition believed economic pressure on advertisers would force a…

77 FR 52313 - Notice of Scope Rulings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-29

..., 2012. A-570-506: Porcelain-On-Steel Cooking Ware from the People's Republic of China Requestor: The Coleman Company, Inc.; the stockpot locking lid of its Signature Series All-In-One Cooking System And Max Series is within the scope of the antidumping duty order; the stockpot cooking base of its Signature...

Effectiveness of Existing Eye Safety Legislation in Arizona.

ERIC Educational Resources Information Center

Gillaspy, Roy Eugene

This study was designed to ascertain the current practices of eye safety in Arizona high school industrial education laboratories, including the enforcement of eye safety legislation, use of eye protection devices, how the eye ware meets the American National Standards Institute specifications, and the teachers' interpretations of the existing eye…

Self-Taught Visually-Guided Pointing for a Humanoid Robot

DTIC Science & Technology

2006-01-01

Brooks, R., Bryson, J., Marjanovic , M., Stein, L. A., & Wessler, M. (1996), Humanoid Soft- ware, Technical report, MIT Arti cial Intelli- gence Lab...8217, Journal of Biomechanics 19, 231{238. Marjanovic , M. (1995), Learning Functional Maps Between Sensorimotor Systems on a Humanoid Robot, Master’s thesis, MIT

Computer-Mediated Corrective Feedback and Language Accuracy in Telecollaborative Exchanges

ERIC Educational Resources Information Center

Vinagre, Margarita; Munoz, Beatriz

2011-01-01

Recent studies illustrate the potential that intercultural telecollaborative exchanges entail for language development through the use of corrective feedback from collaborating partners (Kessler, 2009; Lee, 2008; Sauro, 2009; Ware & O'Dowd, 2008). We build on this growing body of research by presenting the findings of a three-month-long…

An Analysis of Hope as a Psychological Strength

ERIC Educational Resources Information Center

Valle, Michael F.; Huebner, E. Scott; Suldo, Shannon M.

2006-01-01

Psychologists have placed an increased emphasis on identifying psychological strengths that foster healthy development. Hope, as operationalized in Snyder's hope theory [Snyder, C. R., Hoza, B., Pelham, W. E., Rapoff, M., Ware, L., & Danovsky, M., et al. (1997). The development and validation of the children's hope scale. "Journal of Pediatric…

Knowledge at No Cost

ERIC Educational Resources Information Center

Feintuch, Howard

2009-01-01

OpenCourseWare (OCW) program, offered at the Massachusetts Institute of Technology (MIT), provides open access to course materials for a large number of MIT classes. From this resource, American Megan Brewster, a recent graduate working in Guatemala, was able to formulate and implement a complete protocol to tackle Guatemala's need for a plastics…

5 CFR Appendix C to Subpart B of... - Appropriated Fund Wage and Survey Areas

Code of Federal Regulations, 2012 CFR

2012-01-01

... Thomas Tift Turner Ware Atlanta Survey Area Georgia: Butts Cherokee Clayton Cobb De Kalb Douglas Fayette... Elbert Emanuel Glascock Hart Jefferson Jenkins Lincoln Taliaferro Warren Wilkes South Carolina: Allendale... Thomas Trego Wallace Wichita Wilson Woodson Kentucky Lexington Survey Area Kentucky: Bourbon Clark...

5 CFR Appendix C to Subpart B of... - Appropriated Fund Wage and Survey Areas

Code of Federal Regulations, 2014 CFR

2014-01-01

... Thomas Tift Turner Ware Atlanta Survey Area Georgia: Butts Cherokee Clayton Cobb De Kalb Douglas Fayette... Elbert Emanuel Glascock Hart Jefferson Jenkins Lincoln Taliaferro Warren Wilkes South Carolina: Allendale... Thomas Trego Wallace Wichita Wilson Woodson Kentucky Lexington Survey Area Kentucky: Bourbon Clark...

5 CFR Appendix C to Subpart B of... - Appropriated Fund Wage and Survey Areas

Code of Federal Regulations, 2013 CFR

2013-01-01

... Thomas Tift Turner Ware Atlanta Survey Area Georgia: Butts Cherokee Clayton Cobb De Kalb Douglas Fayette... Elbert Emanuel Glascock Hart Jefferson Jenkins Lincoln Taliaferro Warren Wilkes South Carolina: Allendale... Thomas Trego Wallace Wichita Wilson Woodson Kentucky Lexington Survey Area Kentucky: Bourbon Clark...

78 FR 10172 - Lisa Anne Cornell and G. Ware Cornell, Jr. v. Princess Cruise Lines, Ltd. (Corp), Carnival PLC...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-13

.... Princess Cruise Lines, Ltd. (Corp), Carnival PLC, and Carnival Corporation; Notice of Filing of Complaint...,'' against Princess Cruise Lines, Ltd (Corp), Carnival plc, and Carnival Corporation hereinafter... from ports in the United States;'' Respondent Carnival plc ``is a corporation established under the...

VFDs: Are They Electrical Parasites?

ERIC Educational Resources Information Center

Frank, Ned

2013-01-01

Variable Frequency Drives (VFDs) are electronic speed controllers used mainly to modulate and reduce the overall speed and power consumption of an electrical motor. They can be used as soft starters for equipment that has a large rotational mass, thus reducing belt ware and large electrical peaks when starting large pieces of equipment. VFDs have…

Johns Hopkins Bloomberg School of Public Health OpenCourseWare

ERIC Educational Resources Information Center

Kanchanaraksa, Sukon; Gooding, Ira; Klaas, Brian; Yager, James D.

2009-01-01

The need for public health knowledge is ever increasing, but the educational options have been limited to coursework delivered by academics to individuals who can afford the cost of tuition at public health institutions. To overcome this disparity, Johns Hopkins Bloomberg School of Public Health (JHSPH) has joined the Massachusetts Institute of…

Fiestaware as an Icon in the Popular Culture of America.

ERIC Educational Resources Information Center

Dale, Sharon; Dale, J. Alexander

Fiestaware, the brightly colored dinnerware first introduced in the United States in 1936, has been a cultural phenomenon from its inception. This paper seeks to explain the extraordinary popularity of Fiestaware and to understand the role the ware occupies in U.S. popular culture. Fiestaware achieved enormous success, in spite of its introduction…

The Impact of Standards-Based Reform: Applying Brantlinger's Critique of "Hierarchical Ideologies"

ERIC Educational Resources Information Center

Bacon, Jessica; Ferri, Beth

2013-01-01

Brantlinger's [2004b. "Ideologies Discerned, Values Determined: Getting past the Hierarchies of Special Education." In "Ideology and the Politics of (in)Exclusion," edited by L. Ware, 11-31. New York: Peter Lang Publishing] critique of hierarchical ideologies lays bare the logics embedded in standards-based reform. Drawing on…

Range Environmental Assessment for Test Area C-52 Complex, Eglin Air Force Base, Florida

DTIC Science & Technology

2014-10-31

tourism in the region. Promotes and develops general business, trade, and tourism components of the state economy. Chapter 334 Transportation...sale in BWB. 124 Canterbury Circle. Sat. Aug. 23rd, 8am-2pm. Sports equip, house- wares, books, puzzles, linens, glassware, all must go! Indoor sale

Teaching Undergraduate Software Engineering Using Open Source Development Tools

DTIC Science & Technology

2012-01-01

ware. Some example appliances are: a LAMP stack, Redmine, MySQL database, Moodle, Tom- cat on Apache, and Bugzilla. Some of the important features...Ada, C, C++, PHP , Py- thon, etc., and also supports a wide range of SDKs such as Google’s Android SDK and the Google Web Toolkit SDK. Additionally

CrossTalk: The Journal of Defense Software Engineering. Volume 19, Number 11

DTIC Science & Technology

2006-11-01

8>. 7. Wallace, Delores R. Practical Soft- ware Reliability Modeling. Proc. of the 26th Annual NASA Goddard Software Engineering Workshop, Nov. 2001...STAR WARS TO STAR TREK To Request Back Issues on Topics Not Listed Above, Please Contact <stsc. customerservice@hill.af.mil>. About the Authors Kym

The Educational Situation in Utopia: Why "What Is," Is

ERIC Educational Resources Information Center

Seaman, Jayson; Quay, John

2015-01-01

In this response to Molly Ware's review of our 2013 book, "John Dewey and Education Outdoors," we extend her suggestion that complexity be regarded as an important, generative force in education reform. Drawing on Dewey's 1933 "Utopian Schools" speech, we discuss the "level deeper" that Dewey sought as he…

Response Acquisition under Targeted Percentile Schedules: A continuing Quandary for Molar Models of Operant Behavior

DTIC Science & Technology

1993-07-01

dimensions topics such as timing (e.g., Gibbon & Allan, from interresponse-time duration (e.g.. Alle- 1984), numerositv (e.g., Gallistel , 1989), and...Behavior, 51, 145-162. Snapper, A. G., & Inglis, G. B. (1985). SKED-li soft- Gallistel , C. R. (1989). Animal cognition: The repre- ware system. Kalamazoo

Used Jmol to Help Students Better Understand Fluxional Processes

ERIC Educational Resources Information Center

Coleman, William F.; Fedosky, Edward W.

2006-01-01

This new WebWare combines instructional text and Jmol interactive, animated illustrations that help students visualize the mechanism. It is concluded that by animating the fluxional behavior of a simple model for chiral metal catalyst Sn(amidinate)[subscript 2], in which axial/equatorial exchange within the amidinate rings occurs through a Berry…

Why Do People Share Content? Identifying Why Students Support Sharing Course Material

ERIC Educational Resources Information Center

Tromp, Gerhard Wieger; Long, Phillip D.

2013-01-01

To establish which factors predict student intentions to contribute towards an OpenCourseWare site, an online questionnaire was distributed among University of Queensland students via email. The 320 participants completed items that were based on the theory of planned behaviour and were designed to measure attitudes, subjective norms and perceived…

EXTERIOR VIEW, LOOKING SOUTHEAST, WITH FRONT FACADE AND PORCH. FREE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

EXTERIOR VIEW, LOOKING SOUTHEAST, WITH FRONT FACADE AND PORCH. FREE STANDING BRICK GABLED ROOF SHOWS EVIDENCE OF RECENT FIRE WHICH PARTIALLY DESTROYED THE PROPERTY WHICH WAS BUILT IN THE 1840S FOR THE THEN IRON MASTER HORACE WARE. - Shelby Iron Works, Iron Master's House, County Road 42, Shelby, Shelby County, AL

Hydrogeologic data from the US Geological Survey test wells near Waycross, Ware County, Georgia

USGS Publications Warehouse

Matthews, S.E.; Krause, R.E.

1983-01-01

Two wells were constructed near Waycross, Ware County, Georgia, from July 1980 to May 1981 to collect stratigraphic, structural, geophysical, hydrologic, hydraulic, and geochemical information for the U.S. Geological Survey Tertiary Limestone Regional Aquifer-System Analysis. Data collection included geologic sampling and coring, borehole geophysical logging, packer testing, water-level measuring, water-quality sampling, and aquifer testing. In the study area, the Tertiary limestone aquifer system is about 1,300 feet thick and is confined and overlain by about 610 feet of clastic sediments. The aquifer system consists of limestone, dolomite, and minor evaporites and has high porosity and permeability. A 4-day continuous discharge aquifer test was conducted, from which a transmissivity of about 1 million feet squared per day and a storage coefficient of 0.0001 were calculated. Water from the upper part of the aquifer is of a calcium bicarbonate type. The deeper highly mineralized zone produces a sodium bicarbonate type water in which concentrations of magnesium, sulfate, chloride, sodium, and some trace metals increase with depth. (USGS)

Open Course Ware, Distance Education, and 21st Century Geoscience Education

NASA Astrophysics Data System (ADS)

Connors, M. G.

2010-12-01

Open Course Ware (OCW) allows the highest quality educational materials (including videos of lectures from the best classroom lecturers) to find a wide audience. This audience may include many who wish to obtain credentials for formal study yet who are unable to be campus-based students. This opens a role for formal, credentialed and accredited distance education (DE) to efficiently integrate OCW into DE courses. OCW materials will in this manner be able to be used for education of credential-seeking students who would not otherwise benefit from them. Modern presentation methods using the Internet and video (including mobile device) technologies may offer pedagogical advantages over even traditional classroom learning. A detailed analysis of the development of Athabasca University’s PHYS 302 Vibrations and Waves course (based mainly on MIT’s OCW), and application of lessons learned to development of PHYS 305 Electromagnetism is presented. These courses are relevant to the study of geophysics, but examples of GEOL (Geology) courses will also be mentioned, along with an broad overview of OCW resources in Geoscience.

Effects of soda-lime-silica waste glass on mullite formation kinetics and micro-structures development in vitreous ceramics.

PubMed

Marinoni, Nicoletta; D'Alessio, Daniela; Diella, Valeria; Pavese, Alessandro; Francescon, Ferdinando

2013-07-30

The effects of soda-lime waste glass, from the recovery of bottle glass cullet, in partial replacement of Na-feldspar for sanitary-ware ceramic production are discussed. Attention is paid to the mullite growth kinetics and to the macroscopic properties of the final output, the latter ones depending on the developed micro-structures and vitrification grade. Measurements have been performed by in situ high temperature X-ray powder diffraction, scanning electron microscopy, thermal dilatometry, water absorption and mechanical testing. Glass substituting feldspar from 30 to 50 wt% allows one (i) to accelerate the mullite growth reaction kinetics, and (ii) to achieve macroscopic features of the ceramic output that comply with the latest technical requirements. The introduction of waste glass leads to (i) a general saving of fuel and reduction of the CO2-emissions during the firing stage, (ii) a preservation of mineral resources in terms of feldspars, and (iii) an efficient management of the bottle glass refuse by readdressing a part of it in the sanitary-ware manufacturing. Copyright © 2013 Elsevier Ltd. All rights reserved.

The educational situation in Utopia: why what is, is

NASA Astrophysics Data System (ADS)

Seaman, Jayson; Quay, John

2015-03-01

In this response to Molly Ware's review of our 2013 book, John Dewey and Education Outdoors, we extend her suggestion that complexity be regarded as an important, generative force in education reform. Drawing on Dewey's 1933 Utopian Schools speech, we discuss the "level deeper" that Dewey sought as he criticized the method/subject mater dichotomy, which he saw as an artifact of social class carried forward in the form of a curricular debate rather than a natural source of tension that would be productive to democratic education. Dewey radically argued that learning itself contained similar anti-democratic potential. Eschewing the false child versus curriculum dichotomy, Dewey believed complexity as a catalyst for educational action would be achieved by engaging children in historically formed occupations, harnessing the forces that drive technological and cultural evolution in order to spur interest, effort, and the formation of social attitudes among students. Following Ware, we suggest that reformers should seek to understand at a lever deeper the many sources of complexity they encounter as they both challenge and honor what is.

The role of turbulent suppression in the triggering ITBs on C-Mod

NASA Astrophysics Data System (ADS)

Zhurovich, K.; Fiore, C. L.; Ernst, D. R.; Bonoli, P. T.; Greenwald, M. J.; Hubbard, A. E.; Hughes, J. W.; Marmar, E. S.; Mikkelsen, D. R.; Phillips, P.; Rice, J. E.

2007-11-01

Internal transport barriers can be routinely produced in C-Mod steady EDA H-mode plasmas by applying ICRF at |r/a|>= 0.5. Access to the off-axis ICRF heated ITBs may be understood within the paradigm of marginal stability. Analysis of the Te profiles shows a decrease of R/LTe in the ITB region as the RF resonance is moved off axis. Ti profiles broaden as the ICRF power deposition changes from on-axis to off-axis. TRANSP calculations of the Ti profiles support this trend. Linear GS2 calculations do not reveal any difference in ETG growth rate profiles for ITB vs. non-ITB discharges. However, they do show that the region of stability to ITG modes widens as the ICRF resonance is moved outward. Non-linear simulations show that the outward turbulent particle flux exceeds the Ware pinch by factor of 2 in the outer plasma region. Reducing the temperature gradient significantly decreases the diffusive flux and allows the Ware pinch to peak the density profile. Details of these experiments and simulations will be presented.

Migration of formaldehyde from melamine-ware: UK 2008 survey results.

PubMed

Potter, E L J; Bradley, E L; Davies, C R; Barnes, K A; Castle, L

2010-06-01

Fifty melamine-ware articles were tested for the migration of formaldehyde - with hexamethylenetetramine (HMTA) expressed as formaldehyde - to see whether the total specific migration limit (SML(T)) was being observed. The SML(T), given in European Commission Directive 2002/72/EC as amended, is 15 mg kg(-1). Fourier transform-infrared (FT-IR) spectroscopy was carried out on the articles to confirm the plastic type. Articles were exposed to the food simulant 3% (w/v) aqueous acetic acid under conditions representing their worst foreseeable use. Formaldehyde and HMTA in food simulants were determined by a spectrophotometric derivatization procedure. Positive samples were confirmed by a second spectrophotometric procedure using an alternative derivatization agent. As all products purchased were intended for repeat use, three sequential exposures to the simulant were carried out. Formaldehyde was detected in the simulant exposed to 43 samples. Most of the levels found were well below the limits set in law such that 84% of the samples tested were compliant. However, eight samples had formaldehyde levels that were clearly above the legal maximum at six to 65 times the SML(T).

Ambient hemolysis and activation of coagulation is different between HeartMate II and HeartWare left ventricular assist devices.

PubMed

Birschmann, Ingvild; Dittrich, Marcus; Eller, Thomas; Wiegmann, Bettina; Reininger, Armin J; Budde, Ulrich; Strüber, Martin

2014-01-01

Thromboembolic and bleeding events in patients with a left ventricular assist device (LVAD) are still a major cause of complications. Therefore, the balance between anti-coagulant and pro-coagulant factors needs to be tightly controlled. The principle hypothesis of this study is that different pump designs may have an effect on hemolysis and activation of the coagulation system. Referring to this, the HeartMate II (HMII; Thoratec Corp, Pleasanton, CA) and the HeartWare HVAD (HeartWare International Inc, Framingham, MA) were investigated. For 20 patients with LVAD support (n = 10 each), plasma coagulation, full blood count, and clinical chemistry parameters were measured. Platelet function was monitored using platelet aggregometry, platelet function analyzer-100 system ( Siemens, Marburg, Germany), vasodilator-stimulated phosphoprotein phosphorylation assay, immature platelet fraction, platelet-derived microparticles, and von Willebrand diagnostic. Acquired von Willebrand syndrome could be detected in all patients. Signs of hemolysis, as measured by lactate dehydrogenase levels (mean, 470 U/liter HMII, 250 U/liter HVAD; p < 0.001), were more pronounced in the HMII patients. In contrast, D-dimer analysis indicated a significantly higher activation of the coagulation system in HVAD patients (mean, 0.94 mg/liter HMII, 2.01 mg/liter HVAD; p < 0.01). The efficacy of anti-platelet therapy using clopidogrel was not sufficient in more than 50% of the patients. Our results support the finding that all patients with rotary blood pumps suffered from von Willebrand syndrome. In addition, a distinct footprint of effects on hemolysis and the coagulation system can be attributed to different devices. As a consequence, the individual status of the coagulation system needs to be controlled in long-term patients. © 2013 Published by International Society for the Heart and Lung Transplantation on behalf of International Society for Heart and Lung Transplantation.

Identification and Management of Pump Thrombus in the HeartWare Left Ventricular Assist Device System: A Novel Approach Using Log File Analysis.

PubMed

Jorde, Ulrich P; Aaronson, Keith D; Najjar, Samer S; Pagani, Francis D; Hayward, Christopher; Zimpfer, Daniel; Schlöglhofer, Thomas; Pham, Duc T; Goldstein, Daniel J; Leadley, Katrin; Chow, Ming-Jay; Brown, Michael C; Uriel, Nir

2015-11-01

The study sought to characterize patterns in the HeartWare (HeartWare Inc., Framingham, Massachusetts) ventricular assist device (HVAD) log files associated with successful medical treatment of device thrombosis. Device thrombosis is a serious adverse event for mechanical circulatory support devices and is often preceded by increased power consumption. Log files of the pump power are easily accessible on the bedside monitor of HVAD patients and may allow early diagnosis of device thrombosis. Furthermore, analysis of the log files may be able to predict the success rate of thrombolysis or the need for pump exchange. The log files of 15 ADVANCE trial patients (algorithm derivation cohort) with 16 pump thrombus events treated with tissue plasminogen activator (tPA) were assessed for changes in the absolute and rate of increase in power consumption. Successful thrombolysis was defined as a clinical resolution of pump thrombus including normalization of power consumption and improvement in biochemical markers of hemolysis. Significant differences in log file patterns between successful and unsuccessful thrombolysis treatments were verified in 43 patients with 53 pump thrombus events implanted outside of clinical trials (validation cohort). The overall success rate of tPA therapy was 57%. Successful treatments had significantly lower measures of percent of expected power (130.9% vs. 196.1%, p = 0.016) and rate of increase in power (0.61 vs. 2.87, p < 0.0001). Medical therapy was successful in 77.7% of the algorithm development cohort and 81.3% of the validation cohort when the rate of power increase and percent of expected power values were <1.25% and 200%, respectively. Log file parameters can potentially predict the likelihood of successful tPA treatments and if validated prospectively, could substantially alter the approach to thrombus management. Copyright © 2015 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Analysis of melamine migration from melamine food contact articles.

PubMed

Chik, Z; Haron, D E Mohamad; Ahmad, E D; Taha, H; Mustafa, A M

2011-01-01

Migration of melamine has been determined for 41 types of retail melamine-ware products in Malaysia. This study was initiated by the Ministry of Health, Malaysia, in the midst of public anxiety on the possibility of melamine leaching into foods that come into contact with the melamine-ware. Thus, the objective of this study was to investigate the level of melamine migration in melamine utensils available on the market. Samples of melamine tableware, including cups and plates, forks and spoons, tumblers, bowls, etc., were collected from various retail outlets. Following the test guidelines for melamine migration set by the European Committee for Standardisation (CEN 2004) with some modifications, the samples were exposed to two types of food simulants (3% acetic acid and distilled water) at three test conditions (25°C (room temperature), 70 and 100°C) for 30 min. Melamine analysis was carried out using LC-MS/MS with a HILIC column and mobile phase consisting of ammonium acetate/formic acid (0.05%) in water and ammonium acetate/formic acid (0.05%) in acetonitrile (95 : 5, v/v). The limit of quantification (LOQ) was 5 ng/ml. Melamine migration was detected from all samples. For the articles tested with distilled water, melamine migration were [median (interquartile range)] 22.2 (32.6), 49.3 (50.9), 84.9 (89.9) ng/ml at room temperature (25°C), 70 and 100°C, respectively. In 3% acetic acid, melamine migration was 31.5 (35.7), 81.5 (76.2), 122.0 (126.7) ng/ml at room temperature (25°C), 70 and 100°C, respectively. This study suggests that excessive heat and acidity may directly affect melamine migration from melamine-ware products. However the results showed that melamine migration in the tested items were well below the specific migration limit (SML) of 30 mg/kg (30,000 ng/ml) set out in European Commission Directive 2002/72/EC.

Study on the Multi-marker Components Quantitative HPLC Fingerprint of the Compound Chinese Medicine Wuwei Changyanning Granule

PubMed Central

Yang, Xian; Yang, Shui-Ping; Zhang, Xue; Yu, Xiao-Dong; He, Qi-Yi; Wang, Bo-Chu

2014-01-01

The aim of this paper is to develop a rapid and highly sensitive quantitative HPLC fingerprint method with multiple indicators by using the Compound Chinese Medicine Wuwei Changyanning granule and 5 herbs in the prescription. The quantitative fingerprint chromatogram with multiple indicators was investigated. і)6 compositions included rutin, gallic acid, chlorogenic acid, atractylenolide Ⅰ, pachymic acid and apigenin, which originated from 5 herbs respectively, were selected as quantitative compositions, and their contents were determined using HPLC from 11 batches granules and the corresponding 5 medicinal materials. ⅱ) The precision, stability and repeatability of fingerprinting were investigated. In addition, common peaks number, the percentage of non-common peaks and similarity were also studied. Among them, 21 common peaks in the granule could find the source of peaks from the 5 herbs, among of 10 peaks from Niuerfeng, 9 peaks from Laliao, 3 peaks from Baishu, 3 peaks from Fuling and 5 peaks from Guanghuoxiang. The results showed that the identification method of fingerprinting was reliable. PMID:25587307

[Screening of anti-aging active ingredients and mechanism analysis based on molecular docking technology].

PubMed

Du, Ran-Feng; Zhang, Xiao-Hua; Ye, Xiao-Tong; Yu, Wen-Kang; Wang, Yun

2016-07-01

Dampness evil is the source of all diseases, which is easy to cause disease and promote aging, while aging could also promote the occurence and development of diseases. In this paper, the relationship between the dampness evil and aging would be discussed, to find the anti-aging active ingredients in traditional Chinese medicine (TCM), and analyze the anti-aging mechanism of dampness eliminating drug. Molecular docking technology was used, with aging-related mammalian target of rapamycin as the docking receptors, and chemical components of Fuling, Sangzhi, Mugua, Yiyiren and Houpo as the docking molecules, to preliminarily screen the anti-aging active ingredients in dampness eliminating drug. Through the comparison with active drugs already on the market (temsirolimus and everolimus), 12 kinds of potential anti-aging active ingredients were found, but their drug gability still needs further study. The docking results showed that various components in the dampness eliminating drug can play anti-aging activities by acting on mammalian target of rapamycin. This result provides a new thought and direction for the method of delaying aging by eliminating dampness. Copyright© by the Chinese Pharmaceutical Association.

Reply to "Professionals, Oaths and Flashbacks in the University" by Peodair Leihy

ERIC Educational Resources Information Center

Sharrock, Geoff

2011-01-01

This article presents the author's reply to Peodair Leihy's critique of his paper, "Two Hippocratic oaths for higher education," published in this "Journal" (Sharrock, 2010). In this article, the author focuses on several points of disagreement. The selling of wares is not a defining feature of professional work: many doctors and lawyers, for…

77 FR 56237 - Notice of Permit Applications Received Under the Antarctic Conservation Act of 1978 (Pub. L. 95-541)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

... use commercially available, freeze-dried marine bacterium, Vibrio fisheri, NRRL B-11177, for experimental use at the Crary Science and Engineering Center (CSEC) at McMurdo Station. This bacterium is used... bacterium is used with a reconstituting reagent to determine toxicity levels. All laboratory plastic-ware...

Platelet Glycoprotein Ib-IX and Malignancy

DTIC Science & Technology

2010-09-01

provide a unique microenvironment supporting the accumulation of more platelets and the elaboration of a fibrin - rich network produced by coagulation...process and can initiate the formation of a platelet - rich thrombus by tethering the platelet to a thrombogenic surface. Several ligands binding to GP Ib... Platelet Glycoprotein Ib-IX and Malignancy PRINCIPAL INVESTIGATOR: Jerry Ware, Ph.D

Ball clay

USGS Publications Warehouse

Virta, R.L.

2001-01-01

Part of the 2000 annual review of the industrial minerals sector. A general overview of the ball clay industry is provided. In 2000, sales of ball clay reached record levels, with sanitary ware and tile applications accounting for the largest sales. Ball clay production, consumption, prices, foreign trade, and industry news are summarized. The outlook for the ball clay industry is also outlined.

Grammar Package 1. MicroSIFT Courseware Evaluation.

ERIC Educational Resources Information Center

Northwest Regional Educational Lab., Portland, OR.

THE FOLLOWING IS THE FULL TEXT OF THIS DOCUMENT (Except for the Evaluation Summary Table): VERSION: TRS-80. PRODUCER: Micro Learning Ware, P.O. Box 2134, N. Mankato, MN 56001. EVALUATION COMPLETED: June 22, 1982 by the staff and constituents of the Portland Public Schools, Portland, Oregon. COST: $24.95. ABILITY LEVEL: 4-5. SUBJECT: Language arts.…

Use of Open Educational Resources: How, Why and Why Not?

ERIC Educational Resources Information Center

Islim, Omer Faruk; Gurel Koybasi, Nergis A.; Cagiltay, Kursat

2016-01-01

Open Educational Resources (OER) and OpenCourseWare (OCW) target barriers of education and learning by sharing knowledge for free to benefit self-learners, educators, and students. This study aims to investigate the use of OER both as a supplementary resource for a traditional course and as a resource for self-learners. First, the attitudes and…

The Development and Initial Evaluation of the Human Readiness Level Framework

DTIC Science & Technology

2010-06-01

View ICD Initial Capabilities Document ICW Interactive Course Ware ILE Interactive Learning Environment ILT Instructor Led Training IOC...Programmatic Environmental Safety and Health Evaluation PHA Preliminary Hazard Analysis PHL Preliminary Hazard List xiv PM Program Manager PQS...Occupational Health SOW Statement of Work SRD System Requirements Document SPS System Performance Specification SRR System Requirements Review SVR

Wicked Problems Forum: Immigration and Higher Education: From Me to We: Embracing Coperformative Witnessing and Critical Love in the Classroom

ERIC Educational Resources Information Center

Calafell, Bernadette Marie; Chuang, Andy Kai-chun

2018-01-01

Omar Swartz and Ware McGuffey's essay, "Migrating Pedagogy in American Universities: Cultivating Moral Imagination and Social Justice," available in this issue of "Communication Education," offers an overview of the current landscape in higher education and, in particular, the challenges immigrant students face, historically…

7. Detail, 1885 Sanborn Fire Insurance Map, Carlin, Nevada, in ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Detail, 1885 Sanborn Fire Insurance Map, Carlin, Nevada, in collection of Nevada Historical Society, Reno; credit Nevada Historical Society. Engine Stores Building is adjacent to R.R. Repair Shop, and is shown containing Library, Cooper Shop, Office, Ware Room, and Boiler & Engine Room. - Southern Pacific Railroad, Carlin Shops, Foot of Sixth Street, Carlin, Elko County, NV

ESPRIT II

DTIC Science & Technology

1990-01-31

and marketing . nological base for the applications, go;ithms, and soft- ware aspects of neurocomputing. The PYGMALION will lead to the coordination of...this by realizing prototypes in two fields systems, system programming, methodology for system of speech application that represent market sectors of...customer rclationrships These demonstrations will ,,c developed and assessed in throughout the internal market by facilitating product close co

Cleveland Metropolitan School District Human Ware Audit: Findings and Recommendations

ERIC Educational Resources Information Center

Osher, David; Poirier, Jeffrey M.; Dwyer, Kevin P.; Hicks, Regenia; Brown, Leah J.; Lampron, Stephanie; Rodriguez, Carlos

2008-01-01

Children and youth require safe and supportive schools and communities if they are to succeed in school and thrive. These needs are particularly great for children who struggle with the impacts of chronic poverty, lead poisoning and lead effect, community and media violence, drugs and alcohol, trauma and loss. There are many such students in…

Learner Behaviour in a MOOC Practice-Oriented Course: In Empirical Study Integrating TAM and TPB

ERIC Educational Resources Information Center

Yang, Hsi-Hsun; Su, Chung-Ho

2017-01-01

Few practice-oriented courses are currently integrated into online learning platforms, such as OpenCourseWare, Khan Academy, and Massive Open Online Courses (MOOCs). It is worthwhile to explore how learners respond to information technology and new teaching methods when practice-oriented course are placed online. Therefore, this study probes…

State-of-the-Art in Open Courseware Initiatives Worldwide

ERIC Educational Resources Information Center

Vladoiu, Monica

2011-01-01

We survey here the state-of-the-art in open courseware initiatives worldwide. First, the MIT OpenCourseWare project is overviewed, as it has been the real starting point of the OCW movement. Usually, open courseware refers to a free and open digital publication of high quality university level educational materials that are organized as courses,…

Student Initiatives and Missed Learning Opportunities in an IRF Sequence: A Single Case Analysis

ERIC Educational Resources Information Center

Li, Houxiang

2013-01-01

Most conversation analysis (CA) studies of the initiation-response-feedback (IRF; Sinclair & Coulthard, 1975) sequence have focused on teacher actions in the feedback move. In this article, I use CA to analyze student initiatives (Waring, 2011) within an IRF sequence in one excerpt from a Chinese as a foreign language class. The excerpt…

Installation Restoration Program. Preliminary Assessment: 186th Tactical Reconnaissance Group, Mississippi Air National Guard, Meridian Airport, Key Field, Meridian, Mississippi

DTIC Science & Technology

1988-10-01

previous directives and meoranda. Although the DOD IRP and the USEPA Superfund pr"gr ware essentially the sase, differences in the definition of progr...Midway and Wilcox inJ Mississimp, Bulletin 102, Mississippi Geologic Research Papers, Mississippi Geological, Ecnomic and Toporapic Survey, 1964. 16

75 FR 62144 - Porcelain-on-Steel Cooking Ware From China and Taiwan; Top-of-the-Stove Stainless Steel Cooking...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-07

... changes, if any, in the supply and demand conditions or business cycle for the Domestic Like Product that...-3088. Limited disclosure of business proprietary information (BPI) under an administrative protective... Merchandise. If you are a domestic producer, union/worker group, or trade/business association; import/export...

The Doctor Fox Research (1973) Rerevisited: "Educational Seduction" Ruled Out

ERIC Educational Resources Information Center

Peer, Eyal; Babad, Elisha

2014-01-01

In their study about the Dr. Fox lecture, Naftulin, Ware, and Donnelly (1973) claimed that an expressive speaker who delivered an attractive lecture devoid of any content could seduce students into believing that they had learned something significant. Over the decades, the study has been (and still is) cited hundreds of times and used by…

High-Speed Video Analysis in a Conceptual Physics Class

ERIC Educational Resources Information Center

Desbien, Dwain M.

2011-01-01

The use of probe ware and computers has become quite common in introductory physics classrooms. Video analysis is also becoming more popular and is available to a wide range of students through commercially available and/or free software. Video analysis allows for the study of motions that cannot be easily measured in the traditional lab setting…

77 FR 60119 - Proposed Consent Agreements: DesignerWare, LLC, Timothy Kelly and Ronald P. Koller, Aspen Way...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-02

... Rental Agent: the capacity to track the physical location of rented computers via WiFi hotspot locations. The information derived from WiFi hotspot contacts can frequently pinpoint a computer's location to a... a list of publicly available WiFi hotspots with the street addresses for the particular hotspots...

Dang An: A Brief History of the Chinese Imperial Archives and Its Administration

ERIC Educational Resources Information Center

Zhang, Wenxian

2004-01-01

Archives are preserved records of human activities. An account of Chinese archival development is as long as the written records of the Chinese history. Oracle bones, bronze ware, and wood and bamboo strips are the three most important recording forms of the early Chinese civilization, as they represented three major stages of archival development…

[Electrochemical methods of control of iodine contents in drinks].

PubMed

Zakharova, E A; Slepchenko, G B; Kolpakova, E Iu

2001-01-01

The simple and express methods of determination of iodide ions (0.01-0.20 mg/decimeter3) in iodine-enriched drinks by potentiometry and inversion voltamperometry were developed. The studies on influencing a storage time hermetically packaged carbonated beverages, a storage time of the depressurized drinks, stuff of ware on the contents of iodine in drinks are held.

Will MITx Change How We Think about Higher Education?

ERIC Educational Resources Information Center

DiSalvio, Philip

2012-01-01

While many colleges and universities are trying to adapt to the forces affecting higher education today, a recent move by the prestigious Massachusetts Institute of Technology is about to cause a seismic shift. The prototype version of MITx is scheduled for launch in spring 2012. MITx is an outgrowth of MIT OpenCourseWare (OCW), which began in…

A CBO Study. The Budget and Economic Outlook: An Update

DTIC Science & Technology

2006-08-01

Holland wrote the summary. Barry Blom, Mark Booth, and Christina Hawley Anthony wrote Chapter 1, with assistance from David Newman and Eric Schatten...Health Service Human Resources Paul Cullinan Unit Chief Christina Hawley Anthony Unemployment insurance, training programs, Administration on...management Gregory Waring Justice, community and regional development, highways, Amtrak, mass transit Susan Willie Commerce, Small Business

Solvent Effects on Emission Yield and Lifetime for Coumarin Laser Dyes. Requirements for a Rotatory Decay Mechanism.

DTIC Science & Technology

1983-10-31

spectral shifts and sizeable solvent iso- tope effects have been frequently observed for solvent exciplexes , e in contrast to our findings. The results also...49. Chandross, E. A.; "The Exciplex " Gordon, M.; Ware, W. R. (ed.) 4 Academic Press, Inc.: New York; 1975; p 187. SO. a. Beecroft, R. A.; Davidson, R

Educational and Nonprofit Institutions Receiving Prime Contract Awards for RDT&E (Research, Development, Test and Evaluation), Fiscal Year 1975.

DTIC Science & Technology

1975-01-01

i 9 CHAPEL HILL WARE ,’ WILMINGON HCAR so PENNSYLVANIA UNIVERSITY Of 2 1 FNILAOELPNIA Pfa 1 NORTN OAK"TA UNIVERSITY OF in S GRANO FOPKS NOAK • PETER...MAKE FOREST UNIVERSITY * *- *WINSTON SALEM NCAR i TEXAS CHRISTIAN UNIVERSITY ZZ FORT WORTH TEXAS 77 * WASHINGTON STATE UNIVERSITY * .* T XAS

Platelet Glycoprotein lb-1X and Malignancy

DTIC Science & Technology

2010-09-01

supporting the accumulation of more platelets and the elaboration of a fibrin - rich network produced by coagulation factors. This paradigm has been...a platelet - rich thrombus by tethering the platelet to a thrombogenic surface. Several ligands binding to GP Ib-IX have been identified, including...08-1-0576 TITLE: Platelet Glycoprotein lb-1X and Malignancy PRINCIPAL INVESTIGATOR: Dr. Jerry Ware

Reflections on Active Networking

DTIC Science & Technology

2005-01-01

Reflections on Active Networking Jonathan M. Smith CIS Department, University of Pennsylvania jms@cis.upenn.edu Abstract Interactions among...called “ Active Networking” came into being. It demonstrates the deep roots Active Networking has in the programming languages, networking and operating...broader research agenda, and the specific goals pursued in the SwitchWare project. I close by speculating on possible futures for Active Networking

Draft SEI Program Plans: 1994-1998

DTIC Science & Technology

1993-08-01

process must depersonalize risks so they are viewed as opportunities for program success. Factors for communication are in all the method devel...and the undergraduate level to adequately prepare new soft- ware engineers entering the work force. Educators and trainers of current professionals...learning opportu- nities. The technical foundation for many of these products is the evolving SEI model curricula for graduate and undergraduate degree

PRODUCTION OF SLIP CAST CALCIA HOLLOWWARE

DOEpatents

Stoddard, S.D.; Nuckolls, D.E.; Cowan, R.E.

1963-12-31

A method for producing slip cast calcia hollow ware in which a dense calcia grain is suspended in isobutyl acetate or a mixture of tertiary amyl alcohol and o-xylene is presented. A minor amount of triethanolamine and oleic acid is added to the suspension vehicle as viscosity adjusting agents and the suspension is cast in a plaster mold, dried, and fired. (AEC)

Redefining HHS International Response: Challenges and Recommendations for Interagency Partnerships

DTIC Science & Technology

2009-04-01

Approach and Enhance Interagency Planning, 1. 22 David Hinson , U.S. Military Interaction with Humanitarian Assistance Organizations During Small-Scale...Defense University Press, 1996); http://www.dodccrp.org/files/Hayes_Interagency.pdf (accessed March 2, 2009. 31 Hinson , Military Interaction with...Humanitarian Assistance Organizations, 29. 32 Benton and Ware, “Haiti: A Case Study”. 33 Hinson , Military Interaction with Humanitarian Assistance

Viking Software Data

DTIC Science & Technology

1977-05-01

RADC-TR-77-168 Final Technical Report M~ay 1977 ll VIKING SOF11WARE DATA Martin Marietta Corporation Approved for public release; distribution...practices employed on a large and complex system development by the Martin Marietta Corporation. The intent of the RADC program to which this document...the technique are described. The preparation of this report could not have been accomplished without considerable assistance from fellow Martin

40 CFR 63.11438 - What are the standards for new and existing sources?

Code of Federal Regulations, 2010 CFR

2010-07-01

... (a)(1) and (2) of this section: (1) Use natural gas, or equivalent clean-burning fuel, as the kiln fuel; or (2) Use an electric-powered kiln. (b) You must maintain annual wet glaze usage records for... for new and existing sources? (a) For each kiln that fires glazed ceramic ware, you must maintain the...

14. INTERIOR VIEW OF THIRD FLOOR OF FACTORY ADDITION, NORTHWEST ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. INTERIOR VIEW OF THIRD FLOOR OF FACTORY ADDITION, NORTHWEST CORNER OF BUILDING. AT THE CENTER IS THE BUFFING MACHINE, MANUFACTURED BY THE ACME CO. OF DETROIT, MICHIGAN. IT WAS HERE THAT ALUMINUM WARES WERE BROUGHT FOR FINAL GRINDING AND BUFFING. THE HOSES REMOVED DUST AND DEBRIS. - Illinois Pure Aluminum Company, 109 Holmes Street, Lemont, Cook County, IL

Model-It: A Case Study of Learner-Centered Software Design for Supporting Model Building.

ERIC Educational Resources Information Center

Jackson, Shari L.; Stratford, Steven J.; Krajcik, Joseph S.; Soloway, Elliot

Learner-centered software design (LCSD) guides the design of tasks, tools, and interfaces in order to support the unique needs of learners: growth, diversity and motivation. This paper presents a framework for LCSD and describes a case study of its application to the ScienceWare Model-It, a learner-centered tool to support scientific modeling and…

Effects of foliar and tuber sprout suppressants on shelf life of ware potatoes under tropical ambient conditions

USDA-ARS?s Scientific Manuscript database

Potato (Solanum tuberosum) is an important source of dietary carbohydrate and cash income for farmers in the tropical highlands of Kenya. The feasibility for cold storage at the farm level is limited due to the high costs of maintaining such a facility and there is limited data on the long-term post...

OOPS, Turning MIT Opencourseware into Chinese: An Analysis of a Community of Practice of Global Translators

ERIC Educational Resources Information Center

Lee, Mimi Miyoung; Lin, Meng-Fen Grace; Bonk, Curtis J.

2007-01-01

An all-volunteer organization called the Opensource Opencourseware Prototype System (OOPS), headquartered in Taiwan, was initially designed to translate open source materials from MIT OpenCourseWare (OCW) site into Chinese. Given the recent plethora of open educational resources (OER), such as the OCW, the growing use of such resources by the…

Braiding-Machine Operator (cot. small wares; textiles) 6-19.986--Standardization of the General Aptitude Test Battery.

ERIC Educational Resources Information Center

Manpower Administration (DOL), Washington, DC. U.S. Training and Employment Service.

The United States Training and Employment Service General Aptitude Test Battery (GATB), first published in 1947, has been included in a continuing program of research to validate the tests against success in many different occupations. The GATB consists of 12 tests which measure nine aptitudes: General Learning Ability; Verbal Aptitude; Numerical…

Design, Fabrication and Testing of Tunable RF Meta-atoms

DTIC Science & Technology

2012-06-14

Simple cantilever beam with actuation pad covered with a thin dielectric layer for short circuit protection...Cantilever actuation simulated with CoventorWare ® to determine the biasing voltage necessary to draw the cantilevers to the actuation pads ...Capacitive tunable meta-atom fabricated on quartz substrate. The meta-atom had to be cut at the metal trace leading to the cantilever actuation pads

DEVELOPMENT AND REVIEW OF MONITORING METHODS AND RISK ASSESSMENT MODELS USED TO DETERMINE THE EFFECTS OF BIOSOLIDS LAND APPLICATION ON HUMAN HEALTH AND THE ENVIRONMENT

EPA Science Inventory

Development and Review of monitoring methods and risk assessment models for biosolids land application impacts on air and land

Ronald F Herrmann (NRMRL), Mike Broder (NCEA), and Mike Ware (NERL)

Science Questions .

MYP Science Question: What additional model...

76 FR 7534 - Porcelain-on-Steel Cooking Ware from the People's Republic of China: Final Results of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-10

... (``Act''). See Initiation of Five-Year (``Sunset'') Review, 75 FR 60731 (October 1, 2010) (``Sunset...)(3)(B) of the Act and 19 CFR 351.218(e)(1)(ii)(C)(2). As a result of this sunset review, the... Commerce. SUMMARY: On October 1, 2010, the Department of Commerce (``Department'') initiated a sunset...

Management of pump thrombosis in patients with left ventricular assist devices.

PubMed

Stulak, John M; Sharma, Shashank; Maltais, Simon

2015-04-01

The gradual evolution of left ventricular assist device (LVAD) therapy has resulted in a durable option for patients as either a bridge to transplantation (BTT) or a destination therapy (DT). Outcomes with current continuous-flow devices continue to demonstrate significant patient benefit, not only in enhanced survival but also in improved functional capacity and quality of life. While the lessening of adverse events through time has resulted in more widespread adoption of this therapy, there continues to be unintended consequences, including, most notably, infection, bleeding, and thrombosis. Beginning in 2011, centers and collaborative groups began to observe a significant increase in the incidence of pump thrombosis with the HeartMate II LVAD (Thoratec Corp., Pleasanton, CA, USA). However, this clinical scourge is not limited to the HeartMate II, as the HeartWare Ventricular Assist System (HVAD; HeartWare Inc., Framingham, MA, USA) has also had these same issues, which led to pump modifications and the appreciation of more strict control of blood pressure and anticoagulation with this pump design. We review the current status of the field of mechanical circulatory support in its approach to diagnosis, management, and prevention of LVAD pump thrombosis.

Ground-Based Correction of Remote-Sensing Spectral Imagery

NASA Technical Reports Server (NTRS)

Alder-Golden, Steven M.; Rochford, Peter; Matthew, Michael; Berk, Alexander

2007-01-01

Software has been developed for an improved method of correcting for the atmospheric optical effects (primarily, effects of aerosols and water vapor) in spectral images of the surface of the Earth acquired by airborne and spaceborne remote-sensing instruments. In this method, the variables needed for the corrections are extracted from the readings of a radiometer located on the ground in the vicinity of the scene of interest. The software includes algorithms that analyze measurement data acquired from a shadow-band radiometer. These algorithms are based on a prior radiation transport software model, called MODTRAN, that has been developed through several versions up to what are now known as MODTRAN4 and MODTRAN5 . These components have been integrated with a user-friendly Interactive Data Language (IDL) front end and an advanced version of MODTRAN4. Software tools for handling general data formats, performing a Langley-type calibration, and generating an output file of retrieved atmospheric parameters for use in another atmospheric-correction computer program known as FLAASH have also been incorporated into the present soft-ware. Concomitantly with the soft-ware described thus far, there has been developed a version of FLAASH that utilizes the retrieved atmospheric parameters to process spectral image data.

Dosimetric validation of the Acuros XB Advanced Dose Calculation algorithm: fundamental characterization in water

NASA Astrophysics Data System (ADS)

Fogliata, Antonella; Nicolini, Giorgia; Clivio, Alessandro; Vanetti, Eugenio; Mancosu, Pietro; Cozzi, Luca

2011-05-01

This corrigendum intends to clarify some important points that were not clearly or properly addressed in the original paper, and for which the authors apologize. The original description of the first Acuros algorithm is from the developers, published in Physics in Medicine and Biology by Vassiliev et al (2010) in the paper entitled 'Validation of a new grid-based Boltzmann equation solver for dose calculation in radiotherapy with photon beams'. The main equations describing the algorithm reported in our paper, implemented as the 'Acuros XB Advanced Dose Calculation Algorithm' in the Varian Eclipse treatment planning system, were originally described (for the original Acuros algorithm) in the above mentioned paper by Vassiliev et al. The intention of our description in our paper was to give readers an overview of the algorithm, not pretending to have authorship of the algorithm itself (used as implemented in the planning system). Unfortunately our paper was not clear, particularly in not allocating full credit to the work published by Vassiliev et al on the original Acuros algorithm. Moreover, it is important to clarify that we have not adapted any existing algorithm, but have used the Acuros XB implementation in the Eclipse planning system from Varian. In particular, the original text of our paper should have been as follows: On page 1880 the sentence 'A prototype LBTE solver, called Attila (Wareing et al 2001), was also applied to external photon beam dose calculations (Gifford et al 2006, Vassiliev et al 2008, 2010). Acuros XB builds upon many of the methods in Attila, but represents a ground-up rewrite of the solver where the methods were adapted especially for external photon beam dose calculations' should be corrected to 'A prototype LBTE solver, called Attila (Wareing et al 2001), was also applied to external photon beam dose calculations (Gifford et al 2006, Vassiliev et al 2008). A new algorithm called Acuros, developed by the Transpire Inc. group, was built upon many of the methods in Attila, but represents a ground-up rewrite of the solver where the methods were especially adapted for external photon beam dose calculations, and described in Vassiliev et al (2010). Acuros XB is the Varian implementation of the original Acuros algorithm in the Eclipse planning system'. On page 1881, the sentence 'Monte Carlo and explicit LBTE solution, with sufficient refinement, will converge on the same solution. However, both methods produce errors (inaccuracies). In explicit LBTE solution methods, errors are primarily systematic, and result from discretization of the solution variables in space, angle, and energy. In both Monte Carlo and explicit LBTE solvers, a trade-off exists between speed and accuracy: reduced computational time may be achieved when less stringent accuracy criteria are specified, and vice versa' should cite the reference Vassiliev et al (2010). On page 1882, the beginning of the sub-paragraph The radiation transport model should start with 'The following description of the Acuros XB algorithm is as outlined by Vassiliev et al (2010) and reports the main steps of the radiation transport model as implemented in Eclipse'. The authors apologize for this lack of clarity in our published paper, and trust that this corrigendum gives full credit to Vassiliev et al in their earlier paper, with respect to previous work on the Acuros algorithm. However we wish to note that the entire contents of the data and results published in our paper are original and the work of the listed authors. References Gifford K A, Horton J L Jr, Wareing T A, Failla G and Mourtada F 2006 Comparison of a finite-element multigroup discrete-ordinates code with Monte Carlo for radiotherapy calculations Phys. Med. Biol. 51 2253-65 Vassiliev O N, Wareing T A, Davis I M, McGhee J, Barnett D, Horton J L, Gifford K, Failla G, Titt U and Mourtada F 2008 Feasibility of a multigroup deterministic solution method for three-dimensional radiotherapy dose calculations Int. J. Radiat. Oncol. Biol. Phys. 72 220-7 Vassiliev O N, Wareing T A, McGhee J, Failla G, Salehpour M R and Mourtada F 2010 Validation of a new grid based Boltzmann equation solver for dose calculation in radiotherapy with photon beams Phys. Med. Biol. 55 581-98 Wareing T A, McGhee J M, Morel J E and Pautz S D 2001 Discontinuous finite element Sn methods on three-dimensional unstructured grids Nucl. Sci. Eng. 138 256-68

Annual Electronics Manufacturing Seminar Proceedings (16th) Held in Ridgecrest, California on 19-21 February 1992

DTIC Science & Technology

1992-02-21

Retrieval Using the Data Analysis Research Tool ...................... 365 Kevin Holm Comarco, Inc. Ridgecrest, California and Richard Schlein Apple...waring locations codinUsed andsin be ailablemachieryandtechniqusLow, waerS S mple, Smple, ow Average toap rv di eag t preominatedepbishedoinforatighee h...by Kevin Holm Senior Technical Specialist Comarco, Inc. Ridgecrest, California and Richard Schlein Senior Systems Engineer Apple Cnmputer, Inc

Optically Induced Spin Gates in Coupled Quantum Dots Using the Electron-Hole Exchange Interaction

DTIC Science & Technology

2008-09-08

S. Bracker, I. V. Ponomarev, V. L. Korenev , M. E. Ware, M. F. Doty, T. L. Reinecke, and D. Gammon, Science 311, 636 2006. 16L. Wang, A. Rastelli...Doty, I. V. Ponomarev, A. S. Bracker, E. A. Stinaff, V. L. Korenev , T. L. Reinecke, and D. Gammon, Phys. Rev. B 75, 245318 2007. 26M. Bayer et al

Web-ware bioinformatical analysis and structure modelling of N-terminus of human multisynthetase complex auxiliary component protein p43.

PubMed

Deineko, Viktor

2006-01-01

Human multisynthetase complex auxiliary component, protein p43 is an endothelial monocyte-activating polypeptide II precursor. In this study, comprehensive sequence analysis of N-terminus has been performed to identify structural domains, motifs, sites of post-translation modification and other functionally important parameters. The spatial structure model of full-chain protein p43 is obtained.

Patient Satisfaction Survey, 1989-1990

DTIC Science & Technology

1990-07-01

Health Association of America was helpful in providing the GHAA Consumer Satisfaction Survey items. iv PATIENT SATISFACTION SURVEY Background The patient ...Ware, J. E., Jr. (1988). Involving consumers in quality of care assessment. Health Affairs, 2, 33-48. Fisher, A. W. (1971). Patients ’ evaluation of...of America (GHAA) Consumer Satisfaction Survey. Patient Satisfaction Surveys were mailed to 9,000 eligible beneficiaries at 37 Army medical treatment

The "peer" in "peer review"

USGS Publications Warehouse

Perry, Gad; Bertoluci, Jaime; Bury, R. Bruce; Hansen, Robert W.; Jehle, Robert; Measey, John; Moon, Brad R.; Muths, Erin L.; Zuffi, Marco A.L.

2011-01-01

Peer review is the best available mechanism for assessing and improving the quality of scientific work. As herpetology broadens its disciplinary and geographic boundaries, high-quality external review is ever more essential. We are writing this editorial jointly because the review process has become increasingly difficult. The resulting delays slow publication times, negatively affect performance reviews, tenure, promotions, and grant proposal success. It harms authors, agencies, and institutions (Ware 2011).

Developing Simulated Cyber Attack Scenarios Against Virtualized Adversary Networks

DTIC Science & Technology

2017-03-01

MAST is a custom software framework originally designed to facilitate the training of network administrators on live networks using SimWare. The MAST...or any other aspect of this collection of information, including suggestions for reducing this burden, to Washington headquarters Services ...scenario development and testing in a virtual test environment. Commercial and custom software tools that provide the ability to conduct network

Software Architecture Evolution

DTIC Science & Technology

2013-12-01

system’s major components occurring via a Java Message Service message bus [69]. This architecture was designed to promote loose coupling of soft- ware...play reconfiguration of the system. The components were Java -based and platform-independent; the interfaces by which they communicated were based on...The MPCS database, a MySQL database used for storing telemetry as well as some other information, such as logs and commanding data [68]. This

Command History. 1972-1973. Volume 2. Sanitized

DTIC Science & Technology

1973-07-15

E-48 FULL PETROLEUM STORAGE TANK POLICY .............................. E-48 FA CILITY TRA N SFER... storage mission. The actual cost and . Additionally, A.RVN supported common Items which plans ware being developed by ARVN at year end, were found in the... storage - 1 r fn(S) A, intensive -round and -Number not operationally ready for mainten-program for VNAF personnel was launched in ance- 12 November 1972

Cottonwoods of the Midwest: A Community Profile

DTIC Science & Technology

2008-05-01

and frequently abundant woody vines in floodplain forests include grape, bittersweet, greenbrier, poison ivy, Virginia creeper, and virgin’s bower...Weaver 1968). Major tree, shrub , and vine associates of eastern cottonwood are listed in Table A1. Forbs and graminoids may be understory components of...silver maple (Ware and Smith 1939, Albertson and Weaver 1945, Read 1958). Trees, shrubs , and vines associated with plains cottonwood are listed in

78 FR 59968 - Notice of Intent To Repatriate Cultural Items: U.S. Department of the Interior, Bureau of Indian...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-30

... definition of a sacred object. Lineal descendants or representatives of any Indian tribe or Native Hawaiian... the definition of sacred object under 25 U.S.C. 3001. This notice is published as part of the National... sacred object is a bowl, identified by staff at the Arizona State Museum as Tusayan White Ware, and...

Topology Optimization of an Aircraft Wing

DTIC Science & Technology

2015-06-11

Fraction VWT Virtual Wind Tunnel xvi TOPOLOGY OPTIMIZATION OF AN AIRCRAFT WING I. Introduction 1.1 Background Current aircraft wing design , which...ware in order to optimize the design of individual spars and wing-box structures for large commercial aircraft . They considered a hybrid global/local...weight in an aircraft by eliminating unnecessary material. An optimized approach has the potential to streamline the design process by allowing a

Computer-Based Learning in Open and Distance Learning Institutions in Nigeria: Cautions on Use of Internet for Counseling

ERIC Educational Resources Information Center

Okopi, Fidel Onjefu; Odeyemi, Olajumoke Janet; Adesina, Adewale

2015-01-01

The study has identified the areas of strengths and weaknesses in the current use of Computer Based Learning (CBL) tools in Open and Distance Learning (ODL) institutions in Nigeria. To achieve these objectives, the following research questions were proposed: (i) What are the computer-based learning tools (soft and hard ware) that are actually in…

Management Aspects of Software Maintenance.

DTIC Science & Technology

1984-09-01

educated in * the complex nature of software maintenance to be able to properly evaluate and manage the software maintenance effort. In this...maintenance and improvement may be called "software evolution". The soft- ware manager must be Educated in the complex nature cf soft- Iware maintenance to be...complaint of error or request for modification is also studied in order to determine what action needs tc be taken. 2. Define Objective and Approach :

The Role of Context in the Development of Second Language Interactional Competence: A Comparative Microanalysis of Topic Initiation Practices in the Study Abroad Homestay and the Language Classroom

ERIC Educational Resources Information Center

Van Booven, Christopher D.

2017-01-01

This dissertation research aims to better specify the role of context in the development of second language interactional competence. Drawing on conversation-analytic methods and Wong and Waring's (2010) model of interactional practices, I described and compared the opportunities that two study abroad contexts--the homestay and the language…

Controlling the Nuclear Polarization in Quantum Dots Using Optical Pulse Shape with a Modest Bandwidth

DTIC Science & Technology

2011-03-23

R17339 (1996). 22A. S. Bracker, E. A. Stinaff, D. Gammon, M. E. Ware, J. G. Tischler, A. Shabaev, A. L. Efros, D. Park, D. Gershoni, V. L. Korenev , and I...056603 (2010). 26V. L. Korenev , Phys. Rev. Lett. 99, 256405 (2007). 27J. J. Baumberg, S. A. Crooker, D. D. Awschalom, N. Samarth, H. Luo, and J. K

Genomic Comparison of Escherichia coli O104:H4 Isolates from 2009 and 2011 Reveals Plasmid, and Prophage Heterogeneity, Including Shiga Toxin Encoding Phage stx2

DTIC Science & Technology

2012-11-01

306. 70. Smith DL, Rooks DJ, Fogg PC, Darby AC, Thomson NR, et al. (2012) Comparative genomics of Shiga toxin encoding bacteriophages. BMC Genomics 13...genomic rearrangements to lysogenic conversion. Microbiol Mol Biol Rev 68: 560–602. 77. Smith DL, Wareing BM, Fogg PCM, Riley LM, Spencer M, et al

Bacteria, fungi and protozoa paper

EPA Pesticide Factsheets

Bacteria and fungi in source and treated drinking waterThis dataset is associated with the following publication:King , D., S. Pfaller , M. Donohue , S. Vesper , E. Villegas , M. Ware , S. Glassmeyer , M. Vogal, E. Furlong, and D. Kolpin. Microbial pathogens in source and treated waters from drinking water treatment plants in the United States and implications for human health. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 562: 987–995, (2016).

Principles and Foundations for Fractionated Networked Cyber-Physical Systems

DTIC Science & Technology

2012-07-13

spectrum between autonomy to cooperation. Our distributed comput- ing model is based on distributed knowledge sharing, and makes very few assumptions but...over the computation without the need for explicit migration. Randomization techniques will make sure that enough di- versity is maintained to allow...small UAV testbed consisting of 10 inex- pensive quadcopters at SRI. Hard ware-wise, we added heat sinks to mitigate the impact of additional heat that

CrossTalk: The Journal of Defense Software Engineering. Volume 21, Number 1

DTIC Science & Technology

2008-01-01

project manage- ment and the individual components of the software life-cycle model ; it will be awarded for...software professionals that had been formally educated in software project manage- ment. The study indicated that our industry is lacking in program managers...soft- ware developments get bigger, more complicated, and more dependent on senior software pro- fessionals to get the project on the right path

Science Education Standards

NASA Astrophysics Data System (ADS)

Moore, John W.

1998-04-01

1.National Science Education Standards; National Research Council, National Academy Press: Washington, DC, 1996. 2.Benchmarks for Science Literacy; American Association for the Advancement of Science, Oxford University Press: New York, 1993. 3.Chemistry in the National Science Education Standards; American Chemical Society Education Division, Washington, DC, 1997. 4.Crosby, G. A. J. Chem. Educ. 1996, 73, A200-A201. 5.Ware, S. A. J. Chem. Educ. 1996, 73, A307-A308.

Automating Software Design Metrics.

DTIC Science & Technology

1984-02-01

INTRODUCTION 1 ", ... 0..1 1.2 HISTORICAL PERSPECTIVE High quality software is of interest to both the software engineering com- munity and its users. As...contributions of many other software engineering efforts, most notably [MCC 77] and [Boe 83b], which have defined and refined a framework for quantifying...AUTOMATION OF DESIGN METRICS Software metrics can be useful within the context of an integrated soft- ware engineering environment. The purpose of this

Southeast Asia Report.

DTIC Science & Technology

1987-05-20

Vigilantism (Ninez Cacho-Olivares; BUSINESS DAY, 2 Apr 87) 29 - b ’Fanatical1 Anticommünist Group Initiation (THE MANILA TIMES, 3 Apr 87) J ...typical American pro- blem: the absence of effective law and order in a frontier re- gion," says Richard Maxwell Brown in an official report for the... j household wares, toys, ’ chinaware, tobacco, ply- wood, electronic, micro- circuits, tennis balls and acrylic yarn. Bananas are seen to have

Security Awareness Bulletin. Number 2-91, September 1991

DTIC Science & Technology

1991-09-01

governments, competitors, In our rapidly changing workplace, computers and those having criminal intent, that uncontrolled access routinely communicate with...same as above; rental fee is slightly higher. Securily A wareness Bulletin 10 Number 2-91 New AIS Requirements in the Defense Industrial Security...original file copy. But remember, check the original for viruses 6. Files grow in size. Infamous to the Nvir, this before locking and relying upon it as a

Stress Evaluation for the TOW Accuracy Study

DTIC Science & Technology

1991-11-01

possibi_2 effects on performance that ware because of test site factors could not be Assased . Implications of confounding order with test site were...with extended wear. There is no health risk in wearing these devices. The system is described in detail in Appendix B. The activity monitors were used... chemical protective clothing (MOPP IV). All runs were completed during daylight hoars. Each gunner completed the state questionnaire battery about 15

An Interactive Computer Program for Assessing and Using Multiattribute Utility Functions

DTIC Science & Technology

1975-06-01

involved evaluating five options for dealing with the question of legalizing prostitution in the Boston area. These options were strict prohibition...MUFCAP Has 69 Been Applied 5.4.1 Evaluating Health Plans 69 5.4.2 Evaluating Policies for Dealing with 69 Prostitution in the Boston...toleration or benign neglect, regula- tion of prostitution , licensing of individual prostitutes and decriminalization. The attributes ware chosen to

A Cultural Resources Testing Program, Holbrook, Arizona

DTIC Science & Technology

1989-01-01

suggest that the area around Holbrook was affiliated with the Kayenta Anasazi. Close ties, however, were maintained between groups residing on the Puerco...and the Little Colorado rivers, indicated by the common occurrence of early types of Cibola White ware along with the predominant Kayenta types. Most...investigators agree that the Petrified Forest represented a boundary between the Cibola and Kayenta areas (Gumerman and Skinner 1968:188; Granger and

51. UPPER CHAMBER OF BISCUIT KILN No. 4, FROM THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

51. UPPER CHAMBER OF BISCUIT KILN No. 4, FROM THE SECOND FLOOR. ALL BRICK KILNS AT THE MORAVIAN POTTERY AND TILE WORKS HAD TWO CHAMBERS. WARE WAS STACKED IN THE LOWER CHAMBERS FOR FIRING AND THE UPPER CHAMBERS PROVIDED ACCESS TO FLUES AND DAMPERS FROM THE SECOND FLOOR. - Moravian Pottery & Tile Works, Southwest side of State Route 313 (Swamp Road), Northwest of East Court Street, Doylestown, Bucks County, PA

Böttger stoneware from North America and Europe; are they authentic

NASA Astrophysics Data System (ADS)

Swann, Charles P.; Nelson, Christina H.

2000-03-01

In the early 18th century, Johann Friedrich Böttger, an alchemist recently arrived in Dresden, was assigned to ceramic experimentation under the orders of Augustus the Strong, Elector of Saxony and King of Poland. The Elector and his advisors hoped to discover the secret of making hard paste porcelain like the wares imported into Europe from China and Japan. In 1706-1707, Böttger produced his first ceramic body, a red stoneware similar to the wares produced in Yixing, China. The first objects were made following the forms of chinese prototypes or European metalwork of the period. Recently, the authenticity of a number of `Böttger' objects in various museums and private collections in North America and Europe has been questioned. To aide in resolving these questions several non-destructive analytical techniques have been employed, the most important being PIXE. This report is on an initial study of 25 objects with 16 elements from Al to Zr and Pb being analysed. The results strongly suggest three different groupings, one of objects from the Meissen factory during the 20th century, one from the work of Böttger himself early in the 18th century and one from an as yet unknown time period and site. The first two groups were previously identified by one of the authors (C.N.).

Biomimetic hydrogels for biosensor implant biocompatibility: electrochemical characterization using micro-disc electrode arrays (MDEAs).

PubMed

Justin, Gusphyl; Finley, Stephen; Abdur Rahman, Abdur Rub; Guiseppi-Elie, Anthony

2009-02-01

Our interest is in the development of engineered microdevices for continuous remote monitoring of intramuscular lactate, glucose, pH and temperature during post-traumatic hemorrhaging. Two important design considerations in the development of such devices for in vivo diagnostics are discussed; the utility of micro-disc electrode arrays (MDEAs) for electrochemical biosensing and the application of biomimetic, bioactive poly(HEMA)-based hydrogel composites for implant biocompatibility. A poly(HEMA)-based hydrogel membrane containing polyethylene glycol (PEG) was UV cross-linked with tetraethyleneglycol diacrylate following application to MDEAs (50 mum discs) and to 250 mum diameter gold electrodes within 8-well culture ware. Cyclic voltammetry (CV) of the MDEAs revealed a reduction in the apparent diffusion coefficient of ferrocenemonocarboxylic acid (FcCO(2)H), from 6.68 x 10(-5) to 6.74 x 10(-6) cm(2)/s for the uncoated and 6 mum thick hydrogel coated devices, respectively. Single frequency (4 kHz) temporal impedance measurements of the hydrogels in the 8-well culture ware showed a reversible 5% change in the absolute impedance of the hydrogels when exposed to a pH change between 6.1 to 7.2 and a 20% drop between pH 6.1 and 8.8.

Ceramic ware waste as coarse aggregate for structural concrete production.

PubMed

García-González, Julia; Rodríguez-Robles, Desirée; Juan-Valdés, Andrés; Morán-Del Pozo, Julia M; Guerra-Romero, M Ignacio

2015-01-01

The manufacture of any kind of product inevitably entails the production of waste. The quantity of waste generated by the ceramic industry, a very important sector in Spain, is between 5% and 8% of the final output and it is therefore necessary to find an effective waste recovery method. The aim of the study reported in the present article was to seek a sustainable means of managing waste from the ceramic industry through the incorporation of this type of waste in the total replacement of conventional aggregate (gravel) used in structural concrete. Having verified that the recycled ceramic aggregates met all the technical requirements imposed by current Spanish legislation, established in the Code on Structural Concrete (EHE-08), then it is prepared a control concrete mix and the recycled concrete mix using 100% recycled ceramic aggregate instead of coarse natural aggregate. The concretes obtained were subjected to the appropriate tests in order to conduct a comparison of their mechanical properties. The results show that the concretes made using ceramic sanitary ware aggregate possessed the same mechanical properties as those made with conventional aggregate. It is therefore possible to conclude that the reuse of recycled ceramic aggregate to produce recycled concrete is a feasible alternative for the sustainable management of this waste.

Left ventricular assist device: exercise capacity evolution and rehabilitation added value.

PubMed

Lamotte, Michel X; Chimenti, Sara; Deboeck, Gael; Gillet, Alexis; Kacelenenbogen, Raymond; Strapart, Jonathan; Vandeneynde, Frédéric; Van Nooten, Guido; Antoine, Martine

2018-06-01

With more than 15,000 implanted patients worldwide and a survival rate of 80% at 1-year and 59% at 5-years, left ventricular assist device (LVAD) implantation has become an interesting strategy in the management of heart failure patients who are resistant to other kinds of treatment. There are limited data in the literature on the change over time of exercise capacity in LVAD patients, as well as limited knowledge about the beneficial effects that rehabilitation might have on these patients. Therefore, the aim of our study was to evaluate the evolution of exercise capacity on a cohort of patients implanted with the same device (HeartWare © ) and to analyse the potential impact of rehabilitation. Sixty-two patients implanted with a LVAD between June 2011 and June 2015 were screened. Exercise capacity was evaluated by cardiopulmonary exercise testing at 6 weeks, 6 and 12 months after implantation. We have observed significant differences in the exercise capacity and evolution between the trained and non-trained patients. Some of the trained patients nearly normalised their exercise capacity at the end of the rehabilitation programme. Exercise capacity of patient implanted with a HeartWare © LVAD increased in the early period after implantation. Rehabilitation allowed implanted patients to have a significantly better evolution compared to non-rehabilitated patients.

Feasibility Study of Radar-Transmitting Materials.

DTIC Science & Technology

1985-03-15

ABS7RACT It is shown that it is unlikely that the principles that ware originally identified for investigation in this study can be used to obtain...transmitting materials by making the real part nr of the refractive index of the materials equal to one nr = 1. (1.1) A useful application is to obtain...reflectance great. Parrett1 suqaested the investigation of obtaining high microwave transmittance by using surace electron plasmas. Since the resonant

Compilation of Abstracts of Theses Submitted by Candidates for Degrees

DTIC Science & Technology

1987-09-30

Paral- lel, Multiple Backend Database Systems Feudo, C.V. Modern Hardware Tochnololies 88 MAJ , USA 8nd. Sof ware Techniques for Online uatabase Storage...and itsApplication in the War- gaming , Reseamth and Analysis (W.A.R.) Lab Waltens erger, G.M. On Limited War, Escalation 524 CPT,, USRF Control, and...TECHNIQIUES FOR ONLINE DATABASE ,TORAGE AND ACCESS Christopher V. Feudo Ma or, United States Army B.S., United States Military Academy# 1972

"It's Not Their Job to Share Content": A Case Study of the Role of Senior Students in Adapting Teaching Materials as Open Educational Resources at the University of Cape Town

ERIC Educational Resources Information Center

Hodgkinson-Williams, Cheryl; Paskevicius, Michael

2013-01-01

Inspired by the Massachusetts Institute of Technology's landmark decision to make its teaching and learning materials freely available to the public as OpenCourseWare (OCW), many other higher education institutions have followed suit sharing resources now more generally referred to as Open Educational Resources (OER). The University of Cape Town…

Issues Affecting Internet Use in Afghanistan and Developing Countries in the Middle East

DTIC Science & Technology

2003-03-10

World Fashion Wares for Dot-Com Market ," Wall Street Journal, June 12, 2000, pp. B1, B12. Mansell, Robin, " Information and Communication Technologies ...Societies: Information Technology for Sustainable Development, New York: Oxford University Press, 1998. Marsh, Ann, "Mapping a Pan-African Market ...access to and use of information and communication technologies (ICT).[1] This paper examines some recent literature to identify the fundamental

An Empirical Approach to Analysis of Similarities between Software Failure Regions

DTIC Science & Technology

1991-09-01

cycle costs after the soft- ware has been marketed (Alberts, 1976). 1 Unfortunately, extensive software testing is frequently necessary in spite of...incidence is primarily syntactic. This mixing of semantic and syntactic forms in the same analysis could lead to some distortion, especially since the...of formulae to improve readability or to indicate precedence of operations. * All defintions within ’Condition I’ of a failure region are assumed to

Soft X-Ray Photoemission

DTIC Science & Technology

1977-07-01

Edward R, Hahn/MS-X22 Attn: Donald R. McMorrow/MS-G30 Attn: Samuel R. Crawford/MS-531 Ford Aerospace & Comm Operations Ford & Jamboree Roads...80933 Attn: Jerry I. Lubell Attn: Walter E. Ware Attn: John R. Hoffman Attn: Donald H. Bryce Attn: Albert P. Bridges Litton Systems, Inc...International Corp, P.O. Box 3105 Anaheim, CA 92803 Attn: George C. Messenger FB61 Attn: Donald J, Stevens FA70 Attn: K. F. Hull Attn: N. J

Evaluation of the Advanced Situational Awareness Training Pilot Program

DTIC Science & Technology

2017-02-01

M., Holder, L. D., Leibrecht, B. C ., Garland, D. J ., Wampler, R. L., & Matthews, M. D. (2000). Modeling and measuring situation awareness in the...Ware, L. J ., Ratcliff, J . J ., & Irvin, C . R. (2009). Evidence of the camera perspective bias in authentic videotaped interrogations: Implications...Advanced Situational Awareness Training Pilot Program 5a. CONTRACT OR GRANT NUMBER W5J9CQ-11- C -0040 5b. PROGRAM ELEMENT NUMBER 633007 6

21st Summer Farmers’ Market Boasts Quality Goods and Great People | Poster

Cancer.gov

NCI at Frederick’s 21st summer farmers’ market has officially begun, and this year’s vendors invite all employees to visit, browse their wares, and learn about the benefits of consuming all-natural products. The market is held every Tuesday until October 16 from 10:30 a.m. to 1:00 p.m. outside of Building 549—rain, shine, or, in the case of the most recent Tuesday, snow.

STARS Conceptual Framework for Reuse Processes (CFRP). Volume 2: application Version 1.0

DTIC Science & Technology

1993-09-30

Analysis and Design DISA/CIM process x OProcess [DIS93] Feature-Oriented Domain SEI process x Analysis ( FODA ) [KCH+90] JIAWG Object-Oriented Domain JIAWG...Domain Analysis ( FODA ) Feasibility Study. Technical Report CMU/S[1 ,N. I R 21. Soft- ware Engineering Institute, Carnegie Mellon University, Pittsburgh...Electronic Systems Center Air Force Materiel Command, USAF Hanscom AFB, MA 01731-5000 Prepared by: The Boeing Company , IBM, Unisys Corporation, Defense

Feasibility of Isolating Vulnerable Equipment of the Electric Power System from Sources of EMP

DTIC Science & Technology

1978-03-01

Utilities, Colorado Springs, Colorado . Mr. Hugh Chastain, LaPlata Electric Association, Durango , Colcrado. Mr. Robert Kerger and Mr. James Ware...electric power systems, and (b) single-line diagrams for powar systems In the State of Colorado . 2. Determine the feanibility of manual isolation of...vulnerable equipment upon receipt ot’ attack warning. Feasibility should be studied in Colorado Syrings (risk area) and Fr-eemont County (host area) of

Redesign and Rehost of the BIG STICK Nuclear Wargame Simulation

DTIC Science & Technology

1988-12-01

described by Pressman [16]. The 4GT soft- ware development approach consists of four iterative phases: the requirements gathering phase, the design strategy...2. BIG STICK Instructions and Planning Guidance. Air Command and Staff College, Air University, Maxwell AFB AL, 1987. Unpublished Manual. 3. Barry W...Software Engineering Notes, 7:29-32, April 1982. 81 17. Roger S. Pressman . Software Engineering: A Practitioner’s Approach. Mc-Craw-llill Book

Association genetics of oleoresin flow in loblolly pine: discovering genes and predicting phenotype for improved resistance to bark beetles and bioenergy potential

Treesearch

Jared W. Westbrook; Marcio F. R. Resende Jr.; Patricio Munoz; Alejandro R. Walker; Jill L. Wegrzyn; C. Dana Nelson; David B. Neale; Matias Kirst; Salvador A. Gezan; Gary F. Peter; John M. Davis

2013-01-01

In the last decade, outbreaks of bark beetles in coniferous forests of North America have caused unprecedented tree mortality and economic losses (Nowak et al., 2008; van Mantgem et al., 2009; Waring et al., 2009), converting forests that were previously atmospheric carbon sinks into carbon sources (Kurz et al., 2008). Native species of bark beetle rapidly kill healthy...

A Common Programming Language for the Department of Defense--Background and Technical Requirements

DTIC Science & Technology

1976-06-01

Method Findings I. Introduction A. The Problem 1. Software Costs 2. Programming Language 3. Lack of Comrr.onality 4. Common Language 5...accessible soft- ware tools and aids. There are a number of widely held perceptions about the ill effects of the lack of programming language ...cost- effective (at lea~t during development) than de- velopi~g a new programming language specialized to the project. On the other hand,

CrossTalk: The Journal of Defense Software Engineering. Volume 20, Number 3, March 2007

DTIC Science & Technology

2007-03-01

Capability Maturity Model ® Integration (CMMI®). CMU Software Engineering Institute <www.sei.cmu.edu/cmmi>. 5. ISO /IEC 27001 :2005. Information Security...international standards bodies – International Organization for Standardi- zation ( ISO ) and International Electro- technical Commission (IEC) – are working on a...number of projects that affect soft- ware security: • The ISO Technical Management Board (TMB) performs strategic planning and coordination for ISO

Intimate partner violence, technology, and stalking.

PubMed

Southworth, Cynthia; Finn, Jerry; Dawson, Shawndell; Fraser, Cynthia; Tucker, Sarah

2007-08-01

This research note describes the use of a broad range of technologies in intimate partner stalking, including cordless and cellular telephones, fax machines, e-mail, Internet-based harassment, global positioning systems, spy ware, video cameras, and online databases. The concept of "stalking with technology" is reviewed, and the need for an expanded definition of cyberstalking is presented. Legal issues and advocacy-centered responses, including training, legal remedies, public policy issues, and technology industry practices, are discussed.

New Technologies and the World Ahead: The Top 20 Plus 5

DTIC Science & Technology

2011-01-01

Specialized Agent Software Programs. Bots represent the next great milestone in soft- ware development. The general deployment of bots is projected to be in...knowledge and areas of interest. Powerful personal- agent 206 Moving from Vision to Action programs will search the Internet and its databases based on...language- capable chatbot and avatar interfaces that can control electronic data and also change and manipulate things in the physical world. These

Program Manager: Journal of the Defense Systems Management College, Volume 17, Number 3

DTIC Science & Technology

1988-06-01

34 modernizing plants and processes, We have established a network with What does "quality" mean? First, the streamlining management, pooling trade associations...pant an opportunity to reflect on the - Network building may be the first opportunity for some organizational climate and hierarchical managers to...s devop slom p se result of the soaring cost of soft -Software Performance Testing. 3 ware enhancements. This difference in hardware and software

CyberTerrorism: Cyber Prevention vs Cyber Recovery

DTIC Science & Technology

2007-12-01

appropriate available security measures (i.e. appropriate level of spy ware, IDS, and antivirus protection software installed) are unaffected by worm attacks...a worm is a form of a virus designed to copy itself by utilizing e-mail or other software applications. The main goal of using this technique is...to permeate the network or portions of the Internet with malicious code that will affect the performance of certain software applications or will

LEGOS: Object-based software components for mission-critical systems. Final report, June 1, 1995--December 31, 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-08-01

An estimated 85% of the installed base of software is a custom application with a production quantity of one. In practice, almost 100% of military software systems are custom software. Paradoxically, the marginal costs of producing additional units are near zero. So why hasn`t the software market, a market with high design costs and low productions costs evolved like other similar custom widget industries, such as automobiles and hardware chips? The military software industry seems immune to market pressures that have motivated a multilevel supply chain structure in other widget industries: design cost recovery, improve quality through specialization, and enablemore » rapid assembly from purchased components. The primary goal of the ComponentWare Consortium (CWC) technology plan was to overcome barriers to building and deploying mission-critical information systems by using verified, reusable software components (Component Ware). The adoption of the ComponentWare infrastructure is predicated upon a critical mass of the leading platform vendors` inevitable adoption of adopting emerging, object-based, distributed computing frameworks--initially CORBA and COM/OLE. The long-range goal of this work is to build and deploy military systems from verified reusable architectures. The promise of component-based applications is to enable developers to snap together new applications by mixing and matching prefabricated software components. A key result of this effort is the concept of reusable software architectures. A second important contribution is the notion that a software architecture is something that can be captured in a formal language and reused across multiple applications. The formalization and reuse of software architectures provide major cost and schedule improvements. The Unified Modeling Language (UML) is fast becoming the industry standard for object-oriented analysis and design notation for object-based systems. However, the lack of a standard real-time distributed object operating system, lack of a standard Computer-Aided Software Environment (CASE) tool notation and lack of a standard CASE tool repository has limited the realization of component software. The approach to fulfilling this need is the software component factory innovation. The factory approach takes advantage of emerging standards such as UML, CORBA, Java and the Internet. The key technical innovation of the software component factory is the ability to assemble and test new system configurations as well as assemble new tools on demand from existing tools and architecture design repositories.« less

A comparison of two types of running wheel in terms of mouse preference, health, and welfare.

PubMed

Walker, Michael; Mason, Georgia

2018-07-01

Voluntary wheel running occurs in mice of all strains, sexes, and ages. Mice find voluntary wheel running rewarding, and it leads to numerous health benefits. For this reason wheels are used both to enhance welfare and to create models of exercise. However, many designs of running wheel are used. This makes between-study comparisons difficult, as this variability could potentially affect the amount, pattern, and/or intensity of running behaviour, and thence the wheels' effects on welfare and exercise-related changes in anatomy and physiology. This study therefore evaluated two commercially available models, chosen because safe for group-housed mice: Bio Serv®'s "fast-trac" wheel combo and Ware Manufacturing Inc.'s stainless steel mesh 5″ upright wheel. Working with a total of three hundred and fifty one female C57BL/6, DBA/2 and BALB/c mice, we assessed these wheels' relative utilization by mice when access was free; the strength of motivation for each wheel-type when access required crossing an electrified grid; and the impact each wheel had on mouse well-being (inferred from acoustic startle responses and neophobia) and exercise-related anatomical changes (BMI; heart and hind limb masses). Mice ran more on the "fast-trac" wheel regardless of whether both wheel-types were available at once, or only if one was present. In terms of motivation, subjects required to work to access a single wheel worked equally hard for both wheel-types (even if locked and thus not useable for running), but if provided with one working wheel for free and the other type of wheel (again unlocked) accessible via crossing the electrified grid, the "fast-trac" wheel emerged as more motivating, as the Maximum Price Paid for the Ware metal wheel was lower than that paid for the "fast-trac" plastic wheel, at least for C57BL/6s and DBA/2s. No deleterious consequences were noted with either wheel in terms of health and welfare, but only mice with plastic wheels developed significantly larger hearts and hind limbs than control animals with locked wheels. Thus, where differences emerged, Bio Serv®'s "fast-trac" wheel combos appeared to better meet the aims of exercise provision than Ware Manufacturing's steel upright wheels. Copyright © 2018 Elsevier Inc. All rights reserved.

Invariance Testing of the SF-36 Health Survey in Women Breast Cancer Survivors: Do Personal and Cancer-Related Variables Influence the Meaning of Quality of Life Items?

ERIC Educational Resources Information Center

Mosewich, Amber D.; Hadd, Valerie; Crocker, Peter R. E.; Zumbo, Bruno D.

2013-01-01

Quality of life (QoL) is affected by issues specific to illness trajectory and thus, may differ, and potentially take on different meanings, at different stages in the cancer process. A widely used measure of QoL is the SF-36 Health Survey (SF-36; Ware 1993); therefore, support for its appropriateness in a given population is imperative. The…

Simulation and Study of High Workload Operations

DTIC Science & Technology

1974-04-25

way to proceed. Inviting a test pilot to confess he cannot meet a challenge, or a line pilot to admit he is overpaid, is asking for more than verbal...part of the aaalyais looked for differences hstaaea the subjects. Using buskal Msllis one-way analysis of variance tests these ware found to be present...however, recog- nised that the three flights were intentionally designed to be markedly different from one another, and it remains to test the

Defense Environmental Restoration Program Annual Report to Congress for Fiscal Year 1991

DTIC Science & Technology

1992-02-01

facility site cleanups. One key area where the Experts During FY 1991, 253 remedial ( AFB ), California; Fort Dix, New Groups are focusing attention...Dover AFB , Dela- process. Current approaches for is greater than the number of instal- ware; McChord AFB , Washington; selecting remedial approaches dis...lations, as more than one type of and Robbins AFB , Georgia. This courage new and unproven tech- action was taken at some brings to 12 the number of

A Cultural Resources Reconnaissance of the Asan Flood Control Study Area, Asan, Guam,

DTIC Science & Technology

1980-01-01

dentified metal fragments, four fragments of modern ceramic mate- rial (two from plates and two from ceramic tiles), three small fragments of cement, and...applying Spoehr’s ceramic typology as Guam’s Red and Plainware varieties are more difficult to differentiate. Reinman suggested utilizing an analysis of the...temper for seriating cera- mic ware from Guam and established a distinction between Calcar- eous Sand Temper (CST) and Volcanic Sand Temper ( VST ). The

Final Environmental Assessment: Demolition/Restoration of Ipswich Antenna Test Facility

DTIC Science & Technology

2012-05-01

sourc--es \\ Veta quantified b y using fual oU e onsu.mption from the-last full yesr of use ( CY20 1 0). Buildings S-3, S-5, and S-15 ware haated b y #2...the environment. E nvironmental Consequences Environmental analyses focused on the following areas: land use, socioeconomics, utilities...the wetland as possib I e . In addition the Conservation Commission may impose additional requirements such as: staking the wetland boundaries

The German General Staff in World War I

DTIC Science & Technology

1983-06-03

sense, prisoners of a powerful trend of the times, which none oculd easily escape. In the age of Bismarck it may still have beer possible to envisage a...although it is possible that the Russians were mrore aggressive in mounting their attack than the O(ML anticipated. The British capabilities ware...docmnents and prisoners of war, aviation assets and the press. The German cavalry did not perfonn its intelligence nmission i"ell in the Battle of the

Seismological Discrimination and Yield Determination Research

DTIC Science & Technology

1980-02-01

observed short period vertical seismograms for a * Rainier Mesa explosion ....... . .68 iv * LIST OF ILLUSTRATIONS (continued) Figure Page 33. Comparison... mounted on sides 2 and 4. All signals were recorded on a FM instrumenta- tion tape machine with response from dc to 80 kHz. All the charges in each grout...detail. (Probes * were mounted on an external support and held at a nominal 0.2 mm from the Al disks.) 81 SYSTEMS. SCIENCE’ AND SOFT WARE 5.3 RESULTS

Sub-Saharan Africa Report

DTIC Science & Technology

1987-03-24

minister for planning and cooperation, Jose Brito, was referred to as "a militant in Africa’s development." Thus was stressed the " lucid realism and the...It is a dream place, with immense beaches and palm trees. Reminders of its past splendor are magnificent tiles of turquoise blue earthen- ware...fortunes through clever speculation. "Samora is dead, but there is a country to be built, a plan to be continued, a dream to made.an actuality," the pro

Air Force Physical Fitness: An Assessment of Characteristics and Programs which Affect Individual Physical Fitness.

DTIC Science & Technology

1982-09-01

34 -_..... .,.. ........ . . ....... , ::. .. m : 7"= LIST OF TABLES Table Page 2.1 Balke and Ware Correlation of Work Capacity Rating With Oxygen Intake ...it part of their duty to meet fitness standards, include antismoking and drug and a-ohol abuse drives in fitness programs, use percent body fat to...beats per minute was recorded. The researchers found that maximum oxygen intake measured in ml/kdmin was the most satisfactory means of describing

Ramifications of Illegal U.S. Arms Exports

DTIC Science & Technology

1989-03-01

the military goods may not have known and/or cared where their wares would ultimately be delivered. 5. U.S. v. Ken Park , aka Kwan Park, January 1989 The...revealed that Ken Park , acting as the Export Manager of Universal Technology, was involved in illegal export of aircraft parts to South Korea in August...transshipment to Teheran, Iran. On January 13, 1939, Ken Park admitted illegally exporting aircraft parts purchased from HTL. This case not only shows Iran’s

Intelligent Middle-Ware Architecture for Mobile Networks

NASA Astrophysics Data System (ADS)

Rayana, Rayene Ben; Bonnin, Jean-Marie

Recent advances in electronic and automotive industries as well as in wireless telecommunication technologies have drawn a new picture where each vehicle became “fully networked”. Multiple stake-holders (network operators, drivers, car manufacturers, service providers, etc.) will participate in this emerging market, which could grow following various models. To free the market from technical constraints, it is important to return to the basics of the Internet, i.e., providing embarked devices with a fully operational Internet connectivity (IPv6).

JPRS Report, China.

DTIC Science & Technology

1991-05-22

trader who had earlier appealed management work. enterprise difficulties and asked for help in solving problems: "Who asked you to invest in China...11.66 percent dumping rate extension, it may go for as long as 397 days. An appeal for China. In addition, Indian cast iron wares that have may be made...which its own ex- immutable. Upon appeal , investigation must be done on factory prices are used as a basis for deciding a fair price, the basis of the

Semantically Aware Foundation Environment (SAFE) for Clean-Slate Design of Resilient, Adaptive Secure Hosts (CRASH)

DTIC Science & Technology

2016-02-01

system consists of a high-fidelity hardware simulation using field programmable gate arrays (FPGAs), with a set of runtime services (ConcreteWare...perimeter protection, patch, and pray” is not aligned with the threat. Programmers will not bail us out of this situation (by writing defect free code...hosted on a Field Programmable Gate Array (FPGA), with a set of runtime services (concreteware) running on the hardware. Secure applications can be

The Volunteer Army: A Military History Research Collection Bibliography

DTIC Science & Technology

1972-05-01

from the United States Army. Philadelphia: Win. F. Fell and Co., 1903. 157 p. UB788B49. Atrocious food and sanitation and low pay were among the...in the regular aroy t during the Indian Ware. Robertson. Edythe L. Food , ClothinjLand Shelter for the Filghting Man. U.S.A. n.p., photocopy, 11955...Fawcett Publications, 1961. 400 p. E60757 141. Includes chapters on recruiting, food , discipline, medical care, and shelter. U.S. Laws, statutes

Three-dimensional model of the skull and the cranial bones reconstructed from CT scans designed for rapid prototyping process.

PubMed

Skrzat, Janusz; Spulber, Alexandru; Walocha, Jerzy

This paper presents the effects of building mesh models of the human skull and the cranial bones from a series of CT-scans. With the aid of computer so ware, 3D reconstructions of the whole skull and segmented cranial bones were performed and visualized by surface rendering techniques. The article briefly discusses clinical and educational applications of 3D cranial models created using stereolitographic reproduction.

Deploying TSP on a National Scale: An Experience Report from Pilot Projects in Mexico

DTIC Science & Technology

2009-03-01

the culture of Western businesses. To address this, the Ministry of Economy, in coordination with business organizations, education- al institutions...commercial desk- top client -server applications. The TSP builds on and enables the Personal Software Process. The PSP guides individual soft- ware developers...they do their day-to-day work. Al - though a great deal of data is available to manage the project and to manage individual perfor- mance, engineers

Archeological Survey of the New House Site, Harlem Plantation, Plaquemines Parish, Louisiana.

DTIC Science & Technology

1983-10-05

LA R C GOODWIN ET AL. UNCLAssIFIED 05 OCT 83 PD-Rt-83-06 DACW29-83 II 8977 F/6 5/6 N 1.0 , jj8 IM-ff9 1.05 1111_1 MICROCOP RESLUIO TEST CH2.2NIOL BRA...uniits is shown in Table 9. Red colored earthenware has a distinctive paste color, due to the presence o5f i1ron compounds in the clay. Red- ware

Operation BUSTER. Project 2.2. Thermal and Blast Effects on Idealized Forest Fuels

DTIC Science & Technology

1952-04-29

outside the test area . Naturally occurring fuels at the test site mm brush, grass clumps, and Joshua bark — ware studied before the tests and...oharrad« Conclusions based on results and observations from Operation BDSBRt 1. Under fire weather oonditionsi/ in a forest area , atomic ex...following atomic explosions over forest areas * 5* Bomb-induced conreotion does not produce surface winds follow« lag blastHTind effects and need not be

RF Photonic Link Test Bed

DTIC Science & Technology

2004-09-01

TEST BED 6. AUTHOR(S) 1Lt Charles Ware, Paul Payson, Richard Michalak and George Brost 5 . FUNDING NUMBERS C - N/A PE - 62204F...modulator [ 5 ]. As can be deduced from the above equation, biasing the modulator at Vπ/2, or quadrature, allows the device to operate in the most linear...is desirable to have access to the secure surveillance facility added to your 5 RRS badge, since room F-251 is in this area. This allows unescorted

Recent Naval Postgraduate School Publications.

DTIC Science & Technology

1985-09-30

Software and Har ware, Vaxjo, Sweden, Aug. 11-12, 1981 Proc. , (1 S8 1) . SchneidEwind, N F Disciplined approach to real - time software design: A look at...29 p. Zyda, M 3 Real - time contour surface display generation Ercpared for chief of Naval Res., Arlington, Va. Naval Postgraduate School, (NPS-.51-84-O...13), Sept., 1984. 21 p. Zyda M .3 THe fEasibility of a multi rccessor architecture for real - time contour surface is, lay generation Prcparea for Chief

Infrared view of Bangkok, Thailand

NASA Technical Reports Server (NTRS)

1992-01-01

The Bight of Bangkok and the city of Bangkok, Thailand are visible in this west looking view. The city, of almost four million people, long famous as a jewelry, silver and bronze ware trading center is also a major rice grower. Situated in a vast lowland ideal for rice agriculture, it is now a major export commodity. The vast network of canals are used for irrigation and drainage and the deforested hills of the Bilauktaung Range are seen nearby.

What the publisher can teach the patient: intellectual property and privacy in an era of trusted privication.

PubMed

Zittrain, J

2000-05-01

This article begins with a premise that intellectual property and privacy have something significant and yet understated in common: both are about balancing a creator's desire to control a particular set of data with consumers' desires to access and redistribute that data. Both law and technology influence such balancing, making it more or less palatable to use data for particular purposes--whether one is an individual making a copy of a popular song for a friend, or a hospital selling a list of maternity ward patients to a day care service. In the shadow of the Internet's rapid development and concomitant easing of barriers to data sharing, holders of intellectual property are pairing increased legal protection with the technologies of "trusted systems." I describe how these technologies might allow more thorough mass distribution of data, while allowing publishers to retain unprecedented control over their wares. For instance, an e-Book seller might charge one price for a read-only copy that could not be printed or forwarded and charge an additional fee for each copy or printout made. Taking up the case of medical privacy, I then suggest that those who worry about the confidentiality of medical records, particularly as they are digitized by recent congressional mandate, might seek to augment comparatively paltry legal protections with trusted systems technologies. For instance, a trusted system could allow a patient to specify how and by whom her records could be used; within limits, she could allow full access to her primary care physician, while allowing only time-limited access to emergency care providers, non-personally identifiable access to medical researchers, and no access at all for marketing purposes. These technologies could allow for new kinds of privacy protection, without sacrificing the legitimate interests of the consumers of medical records.

Incidence and predictors of myocardial recovery on long-term left ventricular assist device support: Results from the United Network for Organ Sharing database.

PubMed

Pan, Stephen; Aksut, Baran; Wever-Pinzon, Omar E; Rao, Shaline D; Levin, Allison P; Garan, Arthur R; Fried, Justin A; Takeda, Koji; Hiroo, Takayama; Yuzefpolskaya, Melana; Uriel, Nir; Jorde, Ulrich P; Mancini, Donna M; Naka, Yoshifumi; Colombo, Paolo C; Topkara, Veli K

2015-12-01

Mechanical circulatory support (MCS) leads to favorable changes in the failing heart at the molecular, cellular, and structural levels. However, myocardial recovery leading to device explantation is rare. We reasoned that the multicenter United Network for Organ Sharing (UNOS) registry might provide insights into clinical predictors and outcomes of the recovery process. The MCS device data set of the UNOS registry was queried for patients with long-term continuous-flow left ventricular assist devices (CF-LVADs) that were explanted for heart transplantation or indication of recovery. Analysis was restricted to adult patients (≥18 years old) who were listed for an initial heart transplantation. Patients with CF-LVADs that were explanted because of recovery were compared with patients with CF-LVADs who underwent transplantation. We identified 594 patients with HeartMate II devices and 92 patients with HeartWare devices. Duration of support was on average 500.4 ± 325.3 days. In 34 (5.0%) patients, devices were explanted secondary to myocardial recovery. Univariate predictors of recovery in patients with long-term LVADs included younger age (40 years vs 53 years), female sex, lower body mass index (25.7 kg/m(2) vs 27.9 kg/m(2)), non-ischemic etiology (91% vs 59%), lack of implantable cardioverter defibrillator at the time of listing (44% vs 79%), and lower serum creatinine (0.97 mg/dl vs 1.28 mg/dl) (all p < 0.05). In the post-explantation period, freedom from death or transplantation was 66% at 1 year. The incidence of recovery on device support is low in the current MCS era and limited to a select cohort of predominantly young patients with non-ischemic myopathy. Given the high incidence of disease recurrence, patients should be closely followed after device explantation. Copyright © 2015 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Research Investigation Directed Toward Extending the Useful Range of the Electromagnetic Spectrum.

DTIC Science & Technology

1982-03-31

A. Chandross in "The Exciplex ", M. Gordon and W. R. Ware, Ed., Academic Press, New York, 1975, p. 187. (5) K. Rotkiewicz, K. H. Grellmann, and Z. R...reaction of the end groups on the opposite sides of the chain. W_ -( 0 ) In our earlier studies (8 )’ (9 ) we determined that exciplex (excited charge...sandwich type structure. We have used picosecond laser excitation and streak camera-optical multi- channel detection of exciplex fluorescence at

Pyyromethene-BF2 Complexes as Laser Dyes

DTIC Science & Technology

1990-05-24

pyrromethene S1 state via exciplex formation, a pro- cess well known for polyamines [20], was not incompatible with the available information... exciplex formation [21]. Strong fluorescence in a bidentate BF 2 complex with nitrogen and/or oxygen atoms as ligand term’ini was afforded by P-BF2...M. Gordon and W. R. Ware, Eds., "The Exciplex ," Academic Press, New York, 1975. [21] M. E. Huston, K. W. Haider, and A. W. Czarnik, J. Amer. Chem. Soc

A Report on a Study to Explore the Characteristics of Offenders Committing Financially Motivated Crimes Related to the Acquisition, Use and Disposal of Illegal Funds

DTIC Science & Technology

1992-04-01

concept (for a review of some of the issues see Green, 1990; Hirschi & Gottfredson , 1987; Weisburd, Wheeler, Waring & Bode, 1991). The exploration of the...1990; Gross, 1980). Recently, however, Hirschi and Gottfredson (1987) have raised a challenge regarding the concept of white- collar criminals that... Gottfredson , 1987a, 1987b, 1989), they adopt the tenant of classical hedonism--the self-interested pursuit of pleasure and avoidance of pain as the

Examining the Effectiveness of Mindfulness Meditation for Chronic Pain Management in Combat Veterans with Traumatic Brain Injury

DTIC Science & Technology

2013-01-01

third had commented on issues related to his work schedule before losing contact with the researchers. Finally, one patient was excluded due to a...M., Keller, S., & Ware, J. E. (2001). Sleep problems, health- related quality of life, work functioning and health care utilization among the...et al., 2006). Military deployment to a war zone may significantly alter health status and quality of life, elevating the risk of long -term physical

A Study of Time Constraints Related to Facilities Acquisition in Support of New Weapons Systems Initial Beddowns.

DTIC Science & Technology

1981-09-01

under SPO direction in one of three ways: 1) design definition paper studies, 2) hard- ware prototyping, or 3) some combination of both (17:2...initial tooling and production is accom- plished to bring the system production to the planned peak rate . The second period is concerned with follow-on...pro- duction after the peak rate is achieved (3:5-1). Sometime during this phase, program management 20 responsibility transfer (PMRT) is also

Army Logistician. Volume 40, Issue 3, May-June 2008

DTIC Science & Technology

2008-06-01

accessible only with a common access card to mitigate security concerns. A link to the “Unit Special Products” site should be a standard fixture...out how to work it. Initially, she was a little uncertain about how to use it or the accompanying soft- ware, iTunes . But she slowly started to...explore both the iPod and iTunes , and, surprisingly, within a few hours, she was confidently rocking out and downloading music! How did she do it

Operation Unified Response: A Case Study of the Military’s Role in Foreign Disaster Relief Operations

DTIC Science & Technology

2011-05-05

disease danger was exacerbated by the introduction of cholera into post-earthquake Haiti, likely by Nepalese United Nation aiel workers, which caused... Mexico ," MSNBC; 5 September 2007.· U.S. Agency for International Development Office of Foreign Disaster Assistance, Fact Sheet #25, Fiscal Year...March 2011. 29 47 Matt Gutman, "Haiti: As Cholera Spreads, Frustration Builds," ABC News; 18 November 2010. 48 LTC James Ware (US Army, Retired

Highlights in the History of U.S. Army Dentistry

DTIC Science & Technology

2012-01-01

arrived in America in 1778.. He resigned from the navy but in 1780 as a civilian provided dental care to the Comte de Rochambeau’s 6000 man army. He was...Dr. William H. Ware was appointed to practice dentistry and upon his deployment in August 1898 established the first Army field dental clinic in...to reach ever moving troops. Photograph reproduced from Dental Cosmos. 1918;24;10 . 17 9 August 1917 MAJ William H. G. Logan, M.D., D.D.S., a

A Scalable Qubit Architecture Based on Holes in Quantum Dot Molecules

DTIC Science & Technology

2012-09-26

94, 57402 (2005). 19 E. A. Stinaff, M. Scheibner, A. S. Bracker, I. V. Pono- marev, V. L. Korenev , M. E. Ware, M. F. Doty, T. L. Reinecke, and D...Gammon, Science 311, 636 (2006). 20 M. F. Doty, M. Scheibner, I. V. Ponomarev, E. A. Sti- naff, A. S. Bracker, V. L. Korenev , T. L. Reinecke, and D...Gammon, Physical Review Letters 97, 197202 (2006). 21 M. Scheibner, M. Doty, I. Ponomarev, A. Bracker, E. Sti- naff, V. Korenev , T. Reinecke, and D

[Analysis of software for identifying spectral line of laser-induced breakdown spectroscopy based on LabVIEW].

PubMed

Hu, Zhi-yu; Zhang, Lei; Ma, Wei-guang; Yan, Xiao-juan; Li, Zhi-xin; Zhang, Yong-zhi; Wang, Le; Dong, Lei; Yin, Wang-bao; Jia, Suo-tang

2012-03-01

Self-designed identifying software for LIBS spectral line was introduced. Being integrated with LabVIEW, the soft ware can smooth spectral lines and pick peaks. The second difference and threshold methods were employed. Characteristic spectrum of several elements matches the NIST database, and realizes automatic spectral line identification and qualitative analysis of the basic composition of sample. This software can analyze spectrum handily and rapidly. It will be a useful tool for LIBS.

Journal of Special Operations Medicine Volume 1, Edition 2

DTIC Science & Technology

2001-01-01

news.... New Group Surgeons at ONE: LCDR Kevin Walters and CDR Scott Flin; at TWO: LT Jose Henao�, at DEVGRU: CDR Fenton , and at BUD/s: LT Ware. Look...be eligible for this surgery. A common belief is that refractive surgery is a � cosmetic � surgical procedure only designed to free one from wearing...corrective glasses, and that the mili- tary should not be in the � cosmetic � business. How- ever, this is a technique for enhancement of soldier readi

Provider software buyer's guide.

PubMed

1994-03-01

To help long term care providers find new ways to improve quality of care and efficiency, Provider magazine presents the fourth annual listing of software firms marketing computer programs for all areas of nursing facility operations. On the following five pages, more than 80 software firms display their wares, with programs such as minimum data set and care planning, dietary, accounting and financials, case mix, and medication administration records. The guide also charts compatible hardware, integration ability, telephone numbers, company contacts, and easy-to-use reader service numbers.

5th Annual Provider Software Buyer's Guide.

PubMed

1995-03-01

To help long term care providers find new ways to improve quality of care and efficiency, PROVIDER presents the fifth annual listing of software firms marketing computer programs for all areas of long term care operations. On the following five pages, more than 70 software firms display their wares, with programs such as minimum data set and care planning, dietary, accounting and financials, case mix, and medication administration records. The guide also charts compatible hardware, integration ability, telephone numbers, company contacts, and easy-to-use reader service numbers.

Provider software buyer's guide.

PubMed

1993-03-01

To help long term care providers find new ways to improve quality of care and efficiency. Provider magazine presents the third annual listing of software firms marketing computer programs for all areas of nursing facility operations. On the following five pages, more than 80 software firms display their wares, with programs such as minimum data set and care planning, dietary, accounting and financials, case mix, and medication administration records. The guide also charts compatible hardware, integration ability, telephone numbers, company contacts, and easy-to-use reader service numbers.

Summary of a Workshop on Plant Canopy Structure, 27-30 April 1981, Oak Ridge, Tennessee.

DTIC Science & Technology

1982-08-01

relating canopy structure to amounts of water-conducting tissue have mostly been tried for woody trees and shrubs in which sapwood area is used as...Forest Service. 20 pp. Grier, C. C. and R. H. Waring. 1974. Conifer foliage mass related to sapwood area . Forest Sci. 20:205-206. Hallg, F., R. A. A...Plant Canopy Struc- ture was held at Oak Ridge, Tenn. Over 30 individuals representing a broad range of disciplines and specific areas of expertise were

Cultural Resources Survey of Fall River Lake, Kansas.

DTIC Science & Technology

1979-07-01

vessel 1s a globular jar with a constricted orifice. The pottery 1s most often undecorated but when decorated with Incision , 1t occurs mainly on the...stream and east of Fall River. Both phases are represented by pottery (1 Butler sherd and 2 Pomona Ware). Also found was a plano -convex endscraper...Additionally, a longitudinal Incised grooved boatstone was found which according to Flnnegan and Witty (1977:25) 1s "Woodland" 1n time and culture. It

Cost-Benefit Analysis of the Implementation of an Enhanced Recovery Program in Liver Surgery.

PubMed

Joliat, Gaëtan-Romain; Labgaa, Ismaïl; Hübner, Martin; Blanc, Catherine; Griesser, Anne-Claude; Schäfer, Markus; Demartines, Nicolas

2016-10-01

Enhanced recovery after surgery (ERAS) programs have been shown to ease the postoperative recovery and improve clinical outcomes for various surgery types. ERAS cost-effectiveness was demonstrated for colorectal surgery but not for liver surgery. The present study aim was to analyze the implementation costs and benefits of a specific ERAS program in liver surgery. A dedicated ERAS protocol for liver surgery was implemented in our department in July 2013. The subsequent year all consecutive patients undergoing liver surgery were treated according to this protocol (ERAS group). They were compared in terms of real in-hospital costs with a patient series before ERAS implementation (pre-ERAS group). Mean costs per patient were compared with a bootstrap T test. A cost-minimization analysis was performed. Seventy-four ERAS patients were compared with 100 pre-ERAS patients. There were no significant pre- and intraoperative differences between the two groups, except for the laparoscopy number (n = 18 ERAS, n = 9 pre-ERAS, p = 0.010). Overall postoperative complications were observed in 36 (49 %) and 64 patients (64 %) in the ERAS and pre-ERAS groups, respectively (p = 0.046). The median length of stay was significantly shorter for the ERAS group (8 vs. 10 days, p = 0.006). The total mean costs per patient were €38,726 and €42,356 for ERAS and pre-ERAS (p = 0.467). The cost-minimization analysis showed a total mean cost reduction of €3080 per patient after ERAS implementation. ERAS implementation for liver surgery induced a non-significant decrease in cost compared to standard care. Significant decreased complication rate and hospital stay were observed in the ERAS group.

Image simulation for HardWare In the Loop simulation in EO domain

NASA Astrophysics Data System (ADS)

Cathala, Thierry; Latger, Jean

2015-10-01

Infrared camera as a weapon sub system for automatic guidance is a key component for military carrier such as missile for example. The associated Image Processing, that controls the navigation, needs to be intensively assessed. Experimentation in the real world is very expensive. This is the main reason why hybrid simulation also called HardWare In the Loop (HWIL) is more and more required nowadays. In that field, IR projectors are able to cast IR fluxes of photons directly onto the IR camera of a given weapon system, typically a missile seeker head. Though in laboratory, the missile is so stimulated exactly like in the real world, provided a realistic simulation tool enables to perform synthetic images to be displayed by the IR projectors. The key technical challenge is to render the synthetic images at the required frequency. This paper focuses on OKTAL-SE experience in this domain through its product SE-FAST-HWIL. It shows the methodology and Return of Experience from OKTAL-SE. Examples are given, in the frame of the SE-Workbench. The presentation focuses on trials on real operational complex 3D cases. In particular, three important topics, that are very sensitive with regards to IG performance, are detailed: first the 3D sea surface representation, then particle systems rendering especially to simulate flares and at last sensor effects modelling. Beyond "projection mode", some information will be given on the SE-FAST-HWIL new capabilities dedicated to "injection mode".

Mechanical circulatory support and heart transplantation in the Asia Pacific region.

PubMed

Sivathasan, Cumaraswamy; Lim, Choon Pin; Kerk, Ka Lee; Sim, David K L; Mehra, Mandeep R

2017-01-01

Globalization has resulted in epidemiologic transition in developing countries from infectious disease and nutritional deficiencies to non-communicable diseases. Epidemiologic data on heart failure (HF), particularly advanced HF therapy, in Asia are increasingly becoming available, although they remain sparse. Heart transplantation for advanced stage HF remains very low in Asia-approximately 0.075 heart transplants per 1 million population. North America, which comprises 7.5% of the world population, accounted for 55.8% of transplants recorded in the 2012 International Society for Heart and Lung Transplantation (ISHLT) Registry, whereas Asia, with 62.5% of the world population, accounted for 5.7% of transplants. There is also lack of reporting from heart transplant centers in Asia to the ISHLT Registry. Most transplant programs in Asia are in economically stable South East Asian countries, whereas in other parts of developing countries, the cost and health care infrastructures remain prohibitive for the development of these programs. Multi-cultural and racial factors, religious beliefs, and diverse traditions of many centuries have resulted in reluctance to organ donation. Mechanical circulatory support (MCS) is emerging as a viable alternative to transplantation, but despite technical capabilities, limitations in embracing MCS in Asia exist. Discrepant practices in the reimbursement of costly MCS therapy have led to differences in the availability of these devices to patients in the region. The HeartMate II (St. Jude Medical, Inc, St. Paul, MN) left ventricular assist device is currently the most widely used durable device in Asia, whereas the HeartWare HVAD (HeartWare, Inc, Framingham, MA) is used most often in Australia. By September 9, 2015, 341 HeartMate implants (293 as bridge to transplant and 48 as destination therapy) had been performed, of which 180 implants were in Japan. The overall 4-year survival is 88%. The longest duration of support is 6.5 years. By the end of 2015, 243 HeartWare HVADs had been implanted in Asia Pacific. There is a need for focused efforts at improving the reporting of data and intensifying health policy within the region to advocate organ transplantation. Individual governments need to take national responsibility to fulfill organ donation and transplantation needs of their populations. International collaboratives, coordinated by societies such as the ISHLT, will be essential in moving this field forward in Asia Pacific. Copyright © 2016 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Adaptive Significance of ERα Splice Variants in Killifish ...

EPA Pesticide Factsheets

The possibility that chronic, multigenerational exposure to environmental estrogens selects for adaptive hormone response phenotypes is a critical unanswered question. Embryos/larvae of killifish from an estrogenic polluted environment (New Bedford Harbor, NBH), as compared to those from a reference site, overexpress estrogen receptor a (ERa) mRNA but are hypo-responsive to estradiol (E2). Analysis of ERa mRNAs in the two populations revealed differences in splicing of the gene encoding ERa (esr1). Here we tested the transactivation functions of four differentially expressed ERa mRNAs and tracked their association with the hypo-responsive phenotype for three generations after transfer of NBH parents to a clean environment. Deletion variants ERaΔ6 and ERaΔ6 – 8 were specific to NBH killifish; had dominant negative functions in an in vitro reporter assay; and were heritable. Morpholino-mediated induction of ERaΔ6 mRNA in zebrafish embryos verified its role as a dominant negative ER on natural estrogen-responsive promoters. Alternate long (ERaL) and short (ERaS) 5'-variants were similar transcriptionally but differed in estrogen responsiveness (ERaS >> ERaL). ERaS accounted for high total ERa expression in F1 NBH embryos/ larvae but this trait was abolished by transfer to clean water. By contrast, the hypo-responsive phenotype of F1 NBH embryos/larvae persisted after long term lab holding but reverted to a normal or hyper-responsive phenotype after two or thre

Natural Resources Research Program: Proceedings of a Workshop on Operational Management Plans: Improving the Process Held in Arlington, Texas on 5-7 December 1989

DTIC Science & Technology

1991-03-01

direction of the work unit was changed to focus on exchanging information in the form of a workshop. It was * eyman-Dove, Linda, Waring, Michael R., and...plan should be broad in scope and evolutionary in principle to permit subsequent revisions neces- sary to fit changing conditions." Cost estimates for...began to update guidance to the field offices in the area of recreation and natural resource manage- ment. Times had changed . New water resource

An Analysis of the RCA Price-S Cost Estimation Model as it Relates to Current Air Force Computer Software Acquisition and Management.

DTIC Science & Technology

1979-12-01

because of the use of complex computational algorithms (Ref 25). Another important factor effecting the cost of soft- ware is the size of the development...involved the alignment and navigational algorithm portions of the software. The second avionics system application was the development of an inertial...001 1 COAT CONL CREA CINT CMAT CSTR COPR CAPP New Code .001 .001 .001 .001 1001 ,OO .00 Device TDAT T03NL TREA TINT Types o * Quantity OGAT OONL OREA

A Study of the Application of the Lognormal and Gamma Distributions to Corrective Maintenance Repair Time Data.

DTIC Science & Technology

1982-10-01

K-S A R A j 1 10 23 R 3 8 11 16 18 For the lognormal methods the test methods sometimes give different results. The K-S test and the chi-square...significant difference among the three test methods . A previous study has been done using 24 data sets of electronic systems and equipments, using only the W...are suitable descriptors for corrective maintenance repair times, and to estimate the difference caused in assuming an exponential distribution for

Proceedings of the Army Science Conference (15th) Held at West Point, New York on 17-19 June 1986. Volume 2. Principal Authors H through L.

DTIC Science & Technology

1986-06-20

Page Leonard, Joseph M. See Seiders, Barbara A. B. V 189 Linden, Carol D. See Canonico, Peter G. 1 127 Little, James S. A Potential Nerve Agent II 271...Semi-Automated System for Testing 11 235 Waring, Paul P. the Efficacy of Nerve Agent Hawkins, George S. Protection/Decontamination Powanda, Michael...potential uses. Among them are: 1) detection of organofluoro- phosphate chemicals, 2) non-corrosive decontamination of nerve agent mate- rials

Stannosis in Hearth Tinners

PubMed Central

Cole, C. W. D.; Davies, J. V. S. A.; Kipling, M. D.; Ritchie, G. L.

1964-01-01

There have been no published reports of stannosis in tinners. In this paper its occurrence in hearth tinners is described. In hearth tinning molten tin is poured into heated iron hollow-ware and smoothed over the internal surface with a cork bat. Ammonium chloride powder is used as a flux. It is considered that fumes arising in the process from the reaction of the flux and the tin caused a concentration of tin compounds in the atmosphere, and this was the mechanism by which stannosis was produced. The literature on stannosis and tinning is reviewed. Images PMID:14180484

Direct Detection of Time-Resolved Rabi Oscillationsin a Single Quantum Dot via Resonance Fluorescence

DTIC Science & Technology

2013-03-19

Ware, E. A. Stinaff, D. Gammon, M. F. Doty, A. S . Bracker, D. Gershoni, V. L. Korenev , S . C. Bădescu, Y. Lyanda-Geller, and T. L. Reinecke, Phys. Rev...A SINGLE QUANTUM DOT VIA RESONANCE FLUORESCENCE 5a. CONTRACT NUMBER FA8750-12-2-0333 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) J...NUMBER CH 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) University of Michigan 450 Church Street Ann Arbor MI 48109-1040 8. PERFORMING

Optical Signatures of Coupled Quantum Dots

DTIC Science & Technology

2006-02-03

Optical Signatures of Coupled Quantum Dots E. A. Stinaff,1 M. Scheibner,1 A. S . Bracker,1 I. V. Ponomarev,1 V. L. Korenev ,2 M. E. Ware,1 M. F. Doty,1...possibility of optically coupling quantum dots for application in quantum information processing. S emiconductor approaches to quantum information can...REPORTS 3 FEBRUARY 2006 VOL 311 SCIENCE www.sciencemag.org636 o n A ug us t 1 4, 2 00 7 w w w . s ci en ce m ag .o rg D ow nl oa de d fr om Report

CASTING SLIPS FOR FABRICATION OF REFRACTORY METAL WARE

DOEpatents

Stoddard, S.D.; Nuckolls, D.E.; Cowan, R.E.

1962-09-01

A composition is given for slip casting tungsten metal. The composition consists essentially of tungsten metal with an average particle size of 0.9 micron, an organic vehicle such as methyl chloroform, o-xylene, n-butyl acetate, isobutyl acetate, and 1, 1, 2, 2-tetrachlorethane, and a suspending agent such as ethyl cellulose, with the approximate ratio of said vehicle to the tungsten metal being 12 cc of a solution containing from 5 to about 20 grams of said ethyl cellulose in 400 cc of said organic vehicle per 100 grams of metal. (AEC)

Genotoxicity Assessment of Chlorotrifluoroethylene Trimer Acid Using a Battery of In Vitro and In Vivo/In Vitro Assays

DTIC Science & Technology

1990-12-01

in liquid nitrogen. Laboratory cultures were maintained as monolayers at 37 t 1.50C in a humidified atmosphere containing 5 t 1.5% CO2 and were... atmosphere containing 5% CO2. The cells were then washed twice with Dulbecco’s phosphate buffered saline (PBS) and incubated in F12 culture medium for six...time cell cultures ware treated with test or control material for 4 h at 37 t 1.SIA in a humidified atmosphere with 5% CO2 . After treatment, the

ELISA-BASE: An Integrated Bioinformatics Tool for Analyzing and Tracking ELISA Microarray Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, Amanda M.; Collett, James L.; Seurynck-Servoss, Shannon L.

ELISA-BASE is an open-source database for capturing, organizing and analyzing protein enzyme-linked immunosorbent assay (ELISA) microarray data. ELISA-BASE is an extension of the BioArray Soft-ware Environment (BASE) database system, which was developed for DNA microarrays. In order to make BASE suitable for protein microarray experiments, we developed several plugins for importing and analyzing quantitative ELISA microarray data. Most notably, our Protein Microarray Analysis Tool (ProMAT) for processing quantita-tive ELISA data is now available as a plugin to the database.

Preparing for the Implementation of the TRICARE Senior Demonstration Project at the TRICARE Region 11 Lead Agency and Madigan Army Medical Center: A Cast Study.

DTIC Science & Technology

1997-03-01

Network 5. Actuarial Analysis 6. Administration, Staffing and Costs 7. Operations i. Appeals ii. Grievances iii. Enrollment Requirements iv...Security Act as of 8/23/96 with data for 1995." Office of the Actuary (OACT), Health Care Financing Administration. Ware, John, Martha Bayliss, William...8217?’ actuaries consider the inDatient methodology for assessing Lüzz to oe aoequaic, anc p-. methods. DoD Medicare Modeling and Impact Study fWPEHr^* ft 11

Archeological Investigations in Cochiti Reservoir, New Mexico. Volume 4. Adaptive Change in the Northern Rio Grande Valley.

DTIC Science & Technology

1979-01-01

remains for the entire to irrigate their gardens of melons, squashes, onions. chiles . Cochiti region, sunflowers, and tomatoes (Clark 1928:234). Thus...red period Glaze decorated wares also occur in northern and are Agua Fria Glaze-on-red, San Clemente Glaze-polychrome, western Mexico and were...modified from Mera 1933) Group TyoeName Etimated Date of Manufacture (A.D. pre-A Los Padillas G-P 71300 to 1325? A Arenal G-P ?1315 to 13507 Agua Fria G/R

CrossTalk: The Journal of Defense Software Engineering. Volume 19, Number 4

DTIC Science & Technology

2006-04-01

by each task order organization; however, an ACA is only a piece of paper that asks a contrac- tor to play nice. To help socialize the ACAs, the...facu l t y. e rau .edu/kor n/ papers / ESREL04KorneckiZalewski.pdf>. 7. Lougee, H. “DO-178B Certified Soft- ware: A Formal Reuse Analysis Ap- proach...Québec à Montréal as an industrial researcher, and is a member of the International Electronics and En- gineers. He has published more than 10 papers in

The Effects of Personnel Policies on the Retention of Service Couples

DTIC Science & Technology

1982-12-01

Cnealtve an ’ews•e aid II ofned ep Md 1a1milp1f 660 Seek ,nmdbw) Service couples Joint Service couples Dual-career families R727ACY (Ceftef...1wC NGcii OWSOLKT9 / 0 -CU-’UITV :L.*WFICA ION OF T6416 PAGE[ (;aim 5*40e EnerWd)I. separttion from family , and better civilian job. An additional...from family , ana better civiLian job. An 1 additional issue of major importance was the reiuirement for childcars. A number of iasquities ware found

See-What-I-Do: Increasing mentor and trainee sense of co-presence in trauma surgeries with the STAR platform

DTIC Science & Technology

2015-04-30

an named lecture/oration "Present and future of Urologic Robotic Surgery ". Co-PI Popescu described project goals and results to computer science... robotic surgery : a case study’, International Journal of Social Robotics , 5(1):75–88. Darcy, A. E., Hancock, L. E. & Ware, E. J. (2008) ‘A descriptive...Journal of Robotic Surgery , 6(1):53–63. Jacob, M. G., Li, Y. T. & Wachs, J. P. (2012) Gestonurse: a multimodal robotic scrub nurse. In Proceedings

Changing outcomes after heart transplantation in patients with amyloid cardiomyopathy.

PubMed

Davis, Margot K; Lee, Peter H U; Witteles, Ronald M

2015-05-01

Amyloid cardiomyopathy (ACM) is associated with a poor prognosis. Previous reports have suggested unfavorable post-heart transplant (HT) survival in this population compared with other HT recipients. Data from the United Network for Organ Sharing (UNOS) registry were used to study outcomes among ACM patients undergoing HT in the modern era (Era 2, 2008 to 2013) as compared with the historical era (Era 1, 1987 to 2007). One hundred eighty-eight ACM patients underwent primary single-organ HT. Ninety-seven patients (51.6%) were transplanted in Era 1 and 91 (48.4%) in Era 2. ACM patients undergoing HT in Era 2 were older (p < 0.0001), had higher body mass index (p = 0.008) and longer ischemic times (p = 0.02), and were more likely to be African-American (p < 0.0001), UNOS Status 1A (p < 0.0001), male (p = 0.01) and highly sensitized (p < 0.0001) compared with those in Era 1. Compared with patients with other etiologies of restrictive cardiomyopathy (RCM; n = 339 in Era 1, n = 164 in Era 2), adjusted hazard ratios (HRs) for post-HT mortality of ACM were 2.08 (p < 0.0001) in Era 1 and 1.22 (p = not statistically significant) in Era 2. Adjusted HRs for mortality of ACM vs all other diagnoses (n = 36,334 in Era 1, n = 9,225 in Era 2) were 1.84 (p < 0.0001) in Era 1 and 1.38 (p = NS) in Era 2. Although post-HT survival did not change with time among non-ACM RCM patients, post-HT mortality was lower in Era 2 compared with Era 1 among ACM patients (HR 0.49, p = 0.03). Although historically associated with inferior survival, post-HT outcomes in ACM patients in the modern era are now approaching those of non-ACM patients. Changes in patients' demographics suggest that this may be related to improved patient selection, including an increased proportion of patients with transthyretin ACM. HT should be considered for appropriate candidates with ACM. Copyright © 2015 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Maxwell's Enduring Legacy

NASA Astrophysics Data System (ADS)

Longair, Malcolm

2016-07-01

Preface; Acknowledgements; Figure credits; Part I. To 1874: 1. Physics in the nineteenth century; 2. Mathematics and physics in Cambridge in the nineteenth century; Part II. 1874 to 1879: 3. The Maxwell era; Part III. 1879 to 1884: 4. Rayleigh's Quinquennium; Part IV. 1884 to 1919: 5. The challenges facing J. J. Thomson; 6. The J. J. Thomson era, 1884-1900 - the electron; 7. The Thomson era, 1900-19 - atomic structure; Part V. 1919 to 1937: 8. Rutherford at McGill and Manchester Universities - new challenges in Cambridge; 9. The Rutherford era - the radioactivists; 10. Rutherford era - the seeds of the new physics; Part VI. 1938 to 1953: 11. Bragg and the war years; 12. Bragg and the post-war years; Part VII. 1953 to 1971: 13. The Mott era - an epoch of expansion; 14. The Mott era - radio astronomy and high energy physics; 15. The Mott era - the growth of condensed matter physics; Part VIII. 1971 to 1982: 16. The Pippard era - a new laboratory and a new vision; 17. The Pippard era - radio astronomy, high energy physics and laboratory astrophysics; 18. The Pippard era - condensed matter physics; Part IX. 1984 to 1995: 19. The Edwards era - a new epoch of expansion; 20. The Edwards era - new directions in condensed matter physics; 21. The Edwards era - high energy physics and radio astronomy; Part X. 1995 to present: 22. Towards the new millennium and beyond; 23. The evolution of the New Museums site; Notes; Bibliography; Author index; Index.

[Investigation and analysis of status in simulation education of anesthesiology of China].

PubMed

Wang, Tian-long; Xue, Ji-xiu; Xiao, Wei; Wu, Xin-min

2010-03-09

To investigate the status of simulation education of anesthesiology in China. Five hundreds questionnaires were mailed to chairmen of department of anesthesiology in teaching hospitals in 29 provinces and autonomous regions in China. The retrieved questionnaires and data were processed and analyzed with statistics. Sixty one questionnaires were retrieved, and retrieved rate is 12.2%. The result indicated that the theory and knowledge of anesthesiology was adopted for the training of medical students and residents in 2% teaching hospitals, theory and knowledge of anesthesiology combined with problem-based learning discussion in 52% teaching hospitals, theory and knowledge of anesthesiology combined with problem-based learning discussion and simulation training in 46% teaching hospitals. The order of simulation devices possessed was as follows: Basic Life Support (BLS) (79.6%), training model for clinical anesthesia techniques (53.1%) and Advances Life Support (ALS) (51.0%). There were only six teaching hospitals utilized Human Patient Simulator for anesthesia training. The result of evaluation of simulation education showed that 91.2% anesthesiologists recognized it as applicable, 90.1% anesthesiologists recognized it as medical ethic requirement and 86.0% anesthesiologists recognized it as partly close to clinical situation. The degree of cognition of anesthesiologists to simulation education was ordered as follows: manipulation correcting ability (92.6%), procedure controllability (87.0%), training adjustability (76.0%) and patients safety (68.5%). The simulation education of anesthesiology in China is still in the preliminary period. The executive departments of education should enhance supports to the simulation education in both hard ware and in soft ware.

How do the work environment and work safety differ between the dry and wet kitchen foodservice facilities?

PubMed Central

Kim, Jeong-Won; Ju, Se-Young; Go, Eun-Sun

2012-01-01

In order to create a worker-friendly environment for institutional foodservice, facilities operating with a dry kitchen system have been recommended. This study was designed to compare the work safety and work environment of foodservice between wet and dry kitchen systems. Data were obtained using questionnaires with a target group of 303 staff at 57 foodservice operations. Dry kitchen facilities were constructed after 2006, which had a higher construction cost and more finishing floors with anti-slip tiles, and in which employees more wore non-slip footwear than wet kitchen (76.7%). The kitchen temperature and muscular pain were the most frequently reported employees' discomfort factors in the two systems, and, in the wet kitchen, "noise of kitchen" was also frequently reported as a discomfort. Dietitian and employees rated the less slippery and slip related incidents in dry kitchens than those of wet kitchen. Fryer area, ware-washing area, and plate waste table were the slippery areas and the causes were different between the functional areas. The risk for current leakage was rated significantly higher in wet kitchens by dietitians. In addition, the ware-washing area was found to be where employees felt the highest risk of electrical shock. Muscular pain (72.2%), arthritis (39.1%), hard-of-hearing (46.6%) and psychological stress (47.0%) were experienced by employees more than once a month, particularly in the wet kitchen. In conclusion, the dry kitchen system was found to be more efficient for food and work safety because of its superior design and well managed practices. PMID:22977692

How do the work environment and work safety differ between the dry and wet kitchen foodservice facilities?

PubMed

Chang, Hye-Ja; Kim, Jeong-Won; Ju, Se-Young; Go, Eun-Sun

2012-08-01

In order to create a worker-friendly environment for institutional foodservice, facilities operating with a dry kitchen system have been recommended. This study was designed to compare the work safety and work environment of foodservice between wet and dry kitchen systems. Data were obtained using questionnaires with a target group of 303 staff at 57 foodservice operations. Dry kitchen facilities were constructed after 2006, which had a higher construction cost and more finishing floors with anti-slip tiles, and in which employees more wore non-slip footwear than wet kitchen (76.7%). The kitchen temperature and muscular pain were the most frequently reported employees' discomfort factors in the two systems, and, in the wet kitchen, "noise of kitchen" was also frequently reported as a discomfort. Dietitian and employees rated the less slippery and slip related incidents in dry kitchens than those of wet kitchen. Fryer area, ware-washing area, and plate waste table were the slippery areas and the causes were different between the functional areas. The risk for current leakage was rated significantly higher in wet kitchens by dietitians. In addition, the ware-washing area was found to be where employees felt the highest risk of electrical shock. Muscular pain (72.2%), arthritis (39.1%), hard-of-hearing (46.6%) and psychological stress (47.0%) were experienced by employees more than once a month, particularly in the wet kitchen. In conclusion, the dry kitchen system was found to be more efficient for food and work safety because of its superior design and well managed practices.

Mycology at a distance.

PubMed

Koneman, Elmer; Gade, Wayne

2002-01-01

GermWare Mycology is an image-rich, CD-ROM-based instruction divided into tutorial and reference programs. The tutorial program, designed for new students, provides only for sequential progress through each of the subject modules, so that each page of information is seen. In contrast, the reference program allows the more experienced learner with random and direct access to each facet of information. The aspergilli, the agents of chromomycosis, the dermatophytes, the dimorphic fungi, the hyaline molds, the dematiaceous molds, the yeasts, and the zygomyces are divided into separate modules. The tutorial program also includes an opening 'isolation procedures' module, in which details of specimen collection, culture media, and microscopic techniques are presented. The random access program includes system maps separating out each of the fungal species, and flow diagrams allowing an algorithm approach to species identifications. A global map is also included through which each fungal species can be directly accessed by the simple click of the mouse. Random access to information on the ecology, clinical presentations, pathology and therapy of the various mycotic diseases is also a feature of the reference program. A series of self-assessment exercises is included at the end of each module, with immediate 'pop-up' feedback to both correct and incorrect answers. The entire program includes over 2500 screens and over 700 color images and diagrams. GermWare Mycology is available through the Colorado Association for Continuing Medical Laboratory Education (CACMLE), who also can provide continuing education credits for individuals who complete a separate examination. For more information contact CACMLE at (303) 321-1734 or info@cacmle.org.

The Development of Enhanced Recovery After Surgery Across Surgical Specialties.

PubMed

Senturk, James C; Kristo, Gentian; Gold, Jason; Bleday, Ronald; Whang, Edward

2017-09-01

Enhanced recovery after surgery (ERAS ® ) principles have gained traction in variety of surgical disciplines. The promise of a reduced length of stay without compromising patient safety or increasing readmission rates has produced a body of literature examining the implementation of ERAS in the care of general, thoracic, urologic, and gynecologic surgery patients. We performed a review of the literature pertaining to studies of ERAS implementation across colorectal surgery, general surgery, thoracic surgery, urology, and gynecology. The extent of ERAS implementation and reported outcomes across key studies as well as systematic reviews and meta-analyses in each field were summarized. The implementation of ERAS protocols has not been uniform across surgical specialties. Despite this, ERAS has produced improvements in patient outcomes. The most commonly described benefit of ERAS application has been reduced length of stay; complication and readmission rates are most consistently decreased in the colorectal literature. Studies have started to measure more nuanced measures of postoperative patient well-being. Efforts are growing to standardize ERAS protocols across diverse fields and call attention to the need for quality control. Challenges remain in the study and execution of ERAS. Controlling for adherence to ERAS components and implementing uniform ERAS protocols across studies are burgeoning topics that have significant implications for study design. The practice of ERAS and its benefits to patients are expected to evolve. Assessing improvements in postdischarge quality of life, timing of return to work and independent living, and adherence to scheduled delivery of adjuvant treatments will strengthen future ERAS investigations.

The effect of pneumococcal conjugate vaccines on incidence and microbiology associated with complicated acute otitis media.

PubMed

Laursen, B B; Danstrup, C S; Hoffmann, S; Nørskov-Lauritsen, N; Christensen, A L B; Ovesen, T

2017-10-01

The objectives of this study were to investigate the incidence of complicated acute otitis media (cAOM) as well as the associated microbiology before and after introduction of the 7- and 13-valent pneumococcal conjugate vaccines (PCV-7 and -13), respectively. CAOM comprises "heavy" AOM (AOM demanding hospitalization), mastodismus (M) and acute mastoiditis (AM). A retrospective cohort study of the incidence and microbiology associated with cAOM during the non-PCV era, the PCV-7 and 13 eras, respectively. Clinical and microbiological data were prospectively registered in a local database. The incidences of cAOM as well as the distribution of various bacterial strains in the three eras were compared. A total of 246 cases of cAOM (125 in the pre-vaccine period (2001-2006), 50 in the PCV-7 period (2007-2010) and 71 in the PCV-13 period (2011-2015)) were identified. The incidence of hAOM decreased by 62% in the PCV7-era but increased to almost pre-vaccine levels in the PCV-13 era. In the M + AM group, a decrease by almost 21% in the PCV7-era was found compared to the pre vaccine era, whereas the decrease was only 12% in the PCV13-era. The three most common findings in both hAOM and M + AM were Streptococcus pneumonia (SP), group A streptococcus (GAS) and "no growth". In the hAOM group, SP decreased from 38% in the pre-vaccine era to 31% in the PCV7-era and further to 16% in the PCV13-era. GAS decreased from 17% in the pre-vaccine era to 0% in the PCV7-era and 16% in the PCV13-era. The percentage of "no growth" increased from 12% to 38% and 44%, respectively. In the M + AM group, SP decreased to 10% in the PCV13-era compared with 44% in the pre-vaccine era and 41% in the PCV7-era. An increase in GAS from 15% in the pre-vaccine era and PCV7-era to 30% in the PCV13-era was observed. The "no growth" percentage increased from 13% in the pre-vaccine era to 26% in the PCV7-era and 33% in the PCV13-era. Introduction of PCV7 and PCV13 has been associated with an overall reduction of cAOM in Central Region Denmark. Pneumococci were still one of the two most common bacteria species related to cAOM though a decrease in pneumococci positive cases was observed. We found an increase in M + AM induced by GAS and a relatively large increase in "no growth", which might be caused by a more aggressive pre-hospital approach to treatment with antibiotics. Consequently, it is not evident whether the reduction of incidences is caused by the vaccines or a more aggressive antimicrobial attitude to manage AOM. The shift to GAS from SP is worrisome, and therefore continuous surveillance of the microbiology associated with AOM is warranted. Copyright © 2017 Elsevier B.V. All rights reserved.

Recent Reanalysis Activities at ECMWF: Results from ERA-20C and Plans for ERA5

NASA Astrophysics Data System (ADS)

Dragani, R.; Hersbach, H.; Poli, P.; Pebeuy, C.; Hirahara, S.; Simmons, A.; Dee, D.

2015-12-01

This presentation will provide an overview of the most recent reanalysis activities performed at the European Centre for Medium-Range Weather Forecasts (ECMWF). A pilot reanalysis of the 20th-century (ERA-20C) has recently been completed. Funded through the European FP7 collaborative project ERA-CLIM, ERA-20C is part of a suite of experiments that also includes a model-only integration (ERA-20CM) and a land-surface reanalysis (ERA-20CL). Its data assimilation system is constrained by only surface observations obtained from ISPD (3.2.6) and ICOADS (2.5.1). Surface boundary conditions are provided by the Hadley Centre (HadISST2.1.0.0) and radiative forcing follows CMIP5 recommended data sets. First-guess uncertainty estimates are based on a 10-member ensemble of Data Assimilations, ERA-20C ensemble, run prior to ERA-20C using ten SST and sea-ice realizations from the Hadley Centre. In November 2014, the European Commission entrusted ECMWF to run on its behalf the Copernicus Climate Change Service (C3S) aiming at producing quality-assured information about the past, current and future states of the climate at both European and global scales. Reanalysis will be one of the main components of the C3S portfolio and the first one to be produced is a global modern era reanalysis (ERA5) covering the period from 1979 onwards. Based on a recent version of the ECMWF data assimilation system, ERA5 will replace the widely used ERA-Interim dataset. This new production will benefit from a much improved model, and better characterized and exploited observations compared to its predecessor. The first part of the presentation will focus on the ERA-20C production, provide an overview of its main characteristics and discuss some of the key results from its assessment. The second part of the talk will give an overview of ERA5, and briefly discuss some of its challenges.

[Multidisciplinary team building in enhanced recovery after surgery].

PubMed

Jia, W D

2018-01-01

There has been 10 years to explore the road in line with China's actual enhanced recovery after surgery(ERAS) since Academician Li Jieshou introduced the view of ERAS into China. ERAS has been widely carried out in the field of surgery, and gradually formed with Chinese characteristics of ERAS clinical pathway.The clinical implementation of ERAS relies on the effective integration of a series of perioperative methods, and any single technique or method can't completely reduce the perioperative physiological and psychological traumatic stress of the patient, so as to achieve the patient's rapid rehabilitation patient-centered multidisciplinary team(MDT)collaboration is an inevitable trend in ERAS development. On the basis of drawing lessons from foreign experience, the establishment of ERAS-MDT model in line with China's national conditions is a new subject that needs to be studied at present. The construction of ERAS-MDT might promote the development of new ERAS services, new technologies, and ultimately promote the improvement of surgical treatment, and bring the greatest clinical benefit to the society and patients.

Structural insights into cell cycle control by essential GTPase Era.

PubMed

Ji, Xinhua

Era (Escherichia coli Ras-like protein), essential for bacterial cell viability, is composed of an N-terminal GTPase domain and a C-terminal KH domain. In bacteria, it is required for the processing of 16S ribosomal RNA (rRNA) and maturation of 30S (small) ribosomal subunit. Era recognizes 10 nucleotides ( 1530 GAUCACCUCC 1539 ) near the 3' end of 16S rRNA and interacts with helix 45 (h45, nucleotides 1506-1529). GTP binding enables Era to bind RNA, RNA binding stimulates Era's GTP-hydrolyzing activity, and GTP hydrolysis releases Era from matured 30S ribosomal subunit. As such, Era controls cell growth rate via regulating the maturation of the 30S ribosomal subunit. Ribosomes manufacture proteins in all living organisms. The GAUCA sequence and h45 are highly conserved in all three kingdoms of life. Homologues of Era are present in eukaryotic cells. Hence, the mechanism of bacterial Era action also sheds light on the cell cycle control of eukaryotes.

[Soft- and hardware support for the setup for computer tracking of radiation teletherapy].

PubMed

Tarutin, I G; Piliavets, V I; Strakh, A G; Minenko, V F; Golubovskiĭ, A I

1983-06-01

A hard and soft ware computer assisted complex has been worked out for gamma-beam therapy. The complex included all radiotherapeutic units, including a Siemens program controlled betatron with an energy of 42 MEV computer ES-1022, a Medigraf system of the processing of graphic information, a Mars-256 system for control over the homogeneity of distribution of dose rate on the field of irradiation and a package of mathematical programs to select a plan of irradiation of various tumor sites. The prospects of the utilization of such complexes in the dosimetric support of radiation therapy are discussed.

Vibrations of Railroad Due to The Passage of The Underground Train

NASA Astrophysics Data System (ADS)

Konowrocki, Robert; Bajer, Czesław

2010-03-01

In the paper we present results of vibration measurements in the train and on the base of the railroad in tunnels of Warsaw Underground. Measurements were performed at straight and curved sections of the track. The paper is focused on the influence of the lateral slip in rail/wheel contact zone on the generation of vibrations and a noise. Vibrations were analyzed in terms of accelerations, velocities or displacements as a function of time and frequency. Results ware compared with the experiment of rolling of the wheel with lateral sleep. In both cases we observed double periodic oscillations.

National Program for Inspection of Non-Federal Dams. Winsor Dam (MA 00588), Quabbin Spillway (MA 00589), Goodnough Dike (MA 00590), Connecticut River Basin, Ware, Massachusetts. Phase I Inspection Report.

DTIC Science & Technology

1978-09-01

at the en- trance to the channel. Another rockfall occurs along the right side of the channel, about 280 ft. downstream from the channel entrance. The...new level survey on seven settlement observation points at Goodnough Dike, in particular to check the 1973 data at * 27 ,nn lnmnnnm u u ~ l I • lI gI ...Spillway weir masonry to maintain the structure in good condition. 3. Periodically remove brush, saplings and rockfalls from the I spiliway discharge

Software Acquisition Management Practical Experience

DTIC Science & Technology

2009-04-23

t a comp ete m ss on so tware su te n ar Air Force Air Mobility Command declared Initial Operation ...or revised controls areR i t t i f d t l t t ll d d di i li d 43 necessary equ remen s managemen s un amen a o a con ro e an sc p ne...Warner Robins, GA 31088 FAA NAS Plan (TDWR) SOW S ft d l t t d i i t b d t do ware eve opmen managemen an eng neer ng o e con uc e in

Completely non-destructive elemental analysis of bulky samples by PGAA

NASA Astrophysics Data System (ADS)

Oura, Y.; Nakahara, H.; Sueki, K.; Sato, W.; Saito, A.; Tomizawa, T.; Nishikawa, T.

1999-01-01

NBAA (neutron beam activation analysis), which is a combination of PGAA and INAA by a single neutron irradiation, using an internal monostandard method is proposed as a very unique and promising method for the elemental analysis of voluminous and invaluable archaeological samples which do not allow even a scrape of the surface. It was applied to chinawares, Sueki ware, and bronze mirrors, and proved to be a very effective method for nondestructive analysis of not only major elements but also some minor elements such as boron that help solve archaeological problems of ears and sites of their production.

Lightcurve Photometry and H-G Parameters for 1077 Campanula

NASA Astrophysics Data System (ADS)

Franco, Lorenzo

2012-04-01

Photometric observations of main-belt asteroid 1077 Campanula ware made at two observatories over 10 nights from 2011 September-November. Analysis of the resulting data found a synodic period P = 3.85085 ± 0.00005 h with an amplitude AV = 0.24 ± 0.01 mag (corrected to zero phase). The measured absolute magnitude, H = 12.50 ± 0.02 mag, slope parameter G = 0.24 ± 0.03, and color index V-R = 0.40 ± 0.07 mag are consistent with a medium albedo M or S-type object. The diameter is estimated to be D = 9 ± 2 km.

Optimizing Hemodynamic Support of Acute Spinal Cord Injury Based on Injury Mechanism

DTIC Science & Technology

2016-10-01

lnJury Specifics Force Weig Tre.tment Notes ht (k&) 8178 Andrew the Giant Yucatan 1-Apr-16 2585.52 25.0 CNTR PILOTTING: unst1ble MAP 8177 Brett...Hart Yucatan 6-Apr-16 3210.77 26.0 CNTR MAP inf11sion: 8202 Coco B. Ware Yucatan 24-Apr-16 2967.00 26.5 NEQJmp(30 min) 60-min Norepinephrine 20...mmHg above BSL 8192 Diamond D. Page Yucatan 27-Apr-16 3609.00 25.0 CNTR 8179 Edge Yucatan 3-May-16 Contusion: 3423.00 26.0 CNTR Groups: - CNTR: no

Entomological indicators during transmission season of dengue in Silvassa (India).

PubMed

Khan, V; Zala, D B; Srivastava, H C

2015-06-01

The entomological surveillance was conducted in urban, semi-urban/slum, industrial and residential areas during main transmission period from June to November 2012. In residential sites house index was 41.7-35.0, breteau index 71.7-136.7 and container index 11.6-20.2. During transmission period all the values ware much higher than the threshold level. The causes of high values of entomological indicator appeared to be rapid industrialization, unawareness of the conditions or factors that can exacerbate mosquito breeding, water storage habits in community and un-implementation of health related legislation.

Proceedings of the Annual DARPA/AFGL Seismic Research Symposium (10th) Held in Fallbrook, California on May 3-5, 1988. Addendum

DTIC Science & Technology

1990-12-17

were measured with LVDT’s mounted on rings encircling the sample. Axial force was generated from an amplified D/A sinusoidal voltage and up to 1000...19 inch rack mount or stand-alone, 7.0 inches high 10 Mbit Ethernet With on-board Transceiver 1.5 Mb/Sec Asynchronous SCSI Bus UNIX and C right to...use license HA RD WARE 4 or 12 MByte Expansion Memory Boards Monochrome or Color Video, Monitor, Keyboard, and Mouse 19-inch Rack- Mount Removable Disk

Development and Implementation of GPS Correlator Structures in MATLAB and Simulink with Focus on SDR Applications: Implementation of a Standard GPS Correlator Architecture (Baseline) Implementation of the MIT Quicksynch Sparse Algorithm Development and Implementation of Parallel Circular Correlator Constructs

DTIC Science & Technology

2014-05-01

software is available for a wide variety of operating systems , including Unix, FreeBSD, Linux, Solaris, Novell NetWare, OS X, Microsoft Windows, OS/2, TPF...Word for Xenix systems . Subsequent versions were later written for several other platforms including IBM PCs running DOS (1983), Apple Macintosh ...this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204

Volume reduction of hot cell plastic wastes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dykes, F W; Henscheid, J P; Lewis, L C

1989-09-19

The disposal of radioactively-contaminated solid wastes has become a national crisis. In such circumstances, it is imperative that this waste be reduced to minimum volume and be packaged to prevent pollution of the environment. The majority of the solid waste generated at the hot cell under consideration is plastic lab ware. Cutting this waste into small pieces with a hot wire technique reduced the volume 66%. Melting the waste, although more time consuming, reduced the volume 90%. The hot wire technique can also be used to cut up damaged master slave manipulator boots, greatly reducing their disposal volume.

The evolution of the ISOLDE control system

NASA Astrophysics Data System (ADS)

Jonsson, O. C.; Catherall, R.; Deloose, I.; Drumm, P.; Evensen, A. H. M.; Gase, K.; Focker, G. J.; Fowler, A.; Kugler, E.; Lettry, J.; Olesen, G.; Ravn, H. L.; Isolde Collaboration

The ISOLDE on-line mass separator facility is operating on a Personal Computer based control system since spring 1992. Front End Computers accessing the hardware are controlled from consoles running Microsoft Windows ™ through a Novell NetWare4 ™ local area network. The control system is transparently integrated in the CERN wide office network and makes heavy use of the CERN standard office application programs to control and to document the running of the ISOLDE isotope separators. This paper recalls the architecture of the control system, shows its recent developments and gives some examples of its graphical user interface.

The evolution of the ISOLDE control system

NASA Astrophysics Data System (ADS)

Jonsson, O. C.; Catherall, R.; Deloose, I.; Evensen, A. H. M.; Gase, K.; Focker, G. J.; Fowler, A.; Kugler, E.; Lettry, J.; Olesen, G.; Ravn, H. L.; Drumm, P.

1996-04-01

The ISOLDE on-line mass separator facility is operating on a Personal Computer based control system since spring 1992. Front End Computers accessing the hardware are controlled from consoles running Microsoft Windows® through a Novell NetWare4® local area network. The control system is transparently integrated in the CERN wide office network and makes heavy use of the CERN standard office application programs to control and to document the running of the ISOLDE isotope separators. This paper recalls the architecture of the control system, shows its recent developments and gives some examples of its graphical user interface.

Tools and Techniques for Basin-Scale Climate Change Assessment

NASA Astrophysics Data System (ADS)

Zagona, E.; Rajagopalan, B.; Oakley, W.; Wilson, N.; Weinstein, P.; Verdin, A.; Jerla, C.; Prairie, J. R.

2012-12-01

The Department of Interior's WaterSMART Program seeks to secure and stretch water supplies to benefit future generations and identify adaptive measures to address climate change. Under WaterSMART, Basin Studies are comprehensive water studies to explore options for meeting projected imbalances in water supply and demand in specific basins. Such studies could be most beneficial with application of recent scientific advances in climate projections, stochastic simulation, operational modeling and robust decision-making, as well as computational techniques to organize and analyze many alternatives. A new integrated set of tools and techniques to facilitate these studies includes the following components: Future supply scenarios are produced by the Hydrology Simulator, which uses non-parametric K-nearest neighbor resampling techniques to generate ensembles of hydrologic traces based on historical data, optionally conditioned on long paleo reconstructed data using various Markov Chain techniuqes. Resampling can also be conditioned on climate change projections from e.g., downscaled GCM projections to capture increased variability; spatial and temporal disaggregation is also provided. The simulations produced are ensembles of hydrologic inputs to the RiverWare operations/infrastucture decision modeling software. Alternative demand scenarios can be produced with the Demand Input Tool (DIT), an Excel-based tool that allows modifying future demands by groups such as states; sectors, e.g., agriculture, municipal, energy; and hydrologic basins. The demands can be scaled at future dates or changes ramped over specified time periods. Resulting data is imported directly into the decision model. Different model files can represent infrastructure alternatives and different Policy Sets represent alternative operating policies, including options for noticing when conditions point to unacceptable vulnerabilities, which trigger dynamically executing changes in operations or other options. The over-arching Study Manager provides a graphical tool to create combinations of future supply scenarios, demand scenarios, infrastructure and operating policy alternatives; each scenario is executed as an ensemble of RiverWare runs, driven by the hydrologic supply. The Study Manager sets up and manages multiple executions on multi-core hardware. The sizeable are typically direct model outputs, or post-processed indicators of performance based on model outputs. Post processing statistical analysis of the outputs are possible using the Graphical Policy Analysis Tool or other statistical packages. Several Basin Studies undertaken have used RiverWare to evaluate future scenarios. The Colorado River Basin Study, the most complex and extensive to date, has taken advantage of these tools and techniques to generate supply scenarios, produce alternative demand scenarios and to set up and execute the many combinations of supplies, demands, policies, and infrastructure alternatives. The tools and techniques will be described with example applications.

Rework of the ERA software system: ERA-8

NASA Astrophysics Data System (ADS)

Pavlov, D.; Skripnichenko, V.

2015-08-01

The software system that has been powering many products of the IAA during decades has undergone a major rework. ERA has capabilities for: processing tables of observations of different kinds, fitting parameters to observations, integrating equations of motion of the Solar system bodies. ERA comprises a domain-specific language called SLON, tailored for astronomical tasks. SLON provides a convenient syntax for reductions of observations, choosing of IAU standards to use, applying rules for filtering observations or selecting parameters for fitting. Also, ERA includes a table editor and a graph plotter. ERA-8 has a number of improvements over previous versions such as: integration of the Solar system and TT xA1 TDB with arbitrary number of asteroids; option to use different ephemeris (including DE and INPOP); integrator with 80-bit floating point. The code of ERA-8 has been completely rewritten from Pascal to C (for numerical computations) and Racket (for running SLON programs and managing data). ERA-8 is portable across major operating systems. The format of tables in ERA-8 is based on SQLite. The SPICE format has been chosen as the main format for ephemeris in ERA-8.

The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3; end of 16S rRNA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tu, Chao; Zhou, Xiaomei; Tarasov, Sergey G.

2012-03-26

Era, composed of a GTPase domain and a K homology domain, is essential for bacterial cell viability. It is required for the maturation of 16S rRNA and assembly of the 30S ribosomal subunit. We showed previously that the protein recognizes nine nucleotides (1531{sup AUCACCUCC}1539) near the 3{prime} end of 16S rRNA, and that this recognition stimulates GTP-hydrolyzing activity of Era. In all three kingdoms of life, the 1530{sup GAUCA}1534 sequence and helix 45 (h45) (nucleotides 1506-1529) are highly conserved. It has been shown that the 1530{sup GA}1531 to 1530{sup AG}1531 double mutation severely affects the viability of bacteria. However, whethermore » Era interacts with G1530 and/or h45 and whether such interactions (if any) contribute to the stimulation of Era's GTPase activity were not known. Here, we report two RNA structures that contain nucleotides 1506-1542 (RNA301), one in complex with Era and GDPNP (GNP), a nonhydrolysable GTP-analogue, and the other in complex with Era, GNP, and the KsgA methyltransferase. The structures show that Era recognizes 10 nucleotides, including G1530, and that Era also binds h45. Moreover, GTPase assay experiments show that G1530 does not stimulate Era's GTPase activity. Rather, A1531 and A1534 are most important for stimulation and h45 further contributes to the stimulation. Although G1530 does not contribute to the intrinsic GTPase activity of Era, its interaction with Era is important for binding and is essential for the protein to function, leading to the discovery of a new cold-sensitive phenotype of Era.« less

Mechanistic Basis Of Calmodulin Mediated Estrogen Receptor Alpha Activation and Antiestrogen Resistance

DTIC Science & Technology

2010-06-01

for solubility (Figure 5). We call this protein Trx -ERA241-320. We also produced a similar protein construct, but with only residues 241-273 of...ERa, as a “control” (Figure 5). We call this protein Trx -ERA241-273. Because CaM binds tightly to the N-terminal extended ligand binding domain of...ERa (residues 286- 552, see above), we hypothesized that Trx - ERA241-320 would bind tightly to CaM, but that Trx -ERA241-273 would not. The genetic

Singular F(R) cosmology unifying early- and late-time acceleration with matter and radiation domination era

NASA Astrophysics Data System (ADS)

Odintsov, S. D.; Oikonomou, V. K.

2016-06-01

We present some cosmological models which unify the late- and early-time acceleration eras with the radiation and the matter domination era, and we realize the cosmological models by using the theoretical framework of F(R) gravity. Particularly, the first model unifies the late- and early-time acceleration with the matter domination era, and the second model unifies all the evolution eras of our Universe. The two models are described in the same way at early and late times, and only the intermediate stages of the evolution have some differences. Each cosmological model contains two Type IV singularities which are chosen to occur one at the end of the inflationary era and one at the end of the matter domination era. The cosmological models at early times are approximately identical to the R 2 inflation model, so these describe a slow-roll inflationary era which ends when the slow-roll parameters become of order one. The inflationary era is followed by the radiation era and after that the matter domination era follows, which lasts until the second Type IV singularity, and then the late-time acceleration era follows. The models have two appealing features: firstly they produce a nearly scale invariant power spectrum of primordial curvature perturbations and a scalar-to-tensor ratio which are compatible with the most recent observational data and secondly, it seems that the deceleration-acceleration transition is crucially affected by the presence of the second Type IV singularity which occurs at the end of the matter domination era. As we demonstrate, the Hubble horizon at early times shrinks, as expected for an initially accelerating Universe, then during the matter domination era, it expands and finally after the Type IV singularity, the Hubble horizon starts to shrink again, during the late-time acceleration era. Intriguingly enough, the deceleration-acceleration transition, occurs after the second Type IV singularity. In addition, we investigate which F(R) gravity can successfully realize each of the four cosmological epochs.

The Function of Embryonic Stem Cell-expressed RAS (E-RAS), a Unique RAS Family Member, Correlates with Its Additional Motifs and Its Structural Properties.

PubMed

Nakhaei-Rad, Saeideh; Nakhaeizadeh, Hossein; Kordes, Claus; Cirstea, Ion C; Schmick, Malte; Dvorsky, Radovan; Bastiaens, Philippe I H; Häussinger, Dieter; Ahmadian, Mohammad Reza

2015-06-19

E-RAS is a member of the RAS family specifically expressed in embryonic stem cells, gastric tumors, and hepatic stellate cells. Unlike classical RAS isoforms (H-, N-, and K-RAS4B), E-RAS has, in addition to striking and remarkable sequence deviations, an extended 38-amino acid-long unique N-terminal region with still unknown functions. We investigated the molecular mechanism of E-RAS regulation and function with respect to its sequence and structural features. We found that N-terminal extension of E-RAS is important for E-RAS signaling activity. E-RAS protein most remarkably revealed a different mode of effector interaction as compared with H-RAS, which correlates with deviations in the effector-binding site of E-RAS. Of all these residues, tryptophan 79 (arginine 41 in H-RAS), in the interswitch region, modulates the effector selectivity of RAS proteins from H-RAS to E-RAS features. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

The roles of ERAS during cell lineage specification of mouse early embryonic development.

PubMed

Zhao, Zhen-Ao; Yu, Yang; Ma, Huai-Xiao; Wang, Xiao-Xiao; Lu, Xukun; Zhai, Yanhua; Zhang, Xiaoxin; Wang, Haibin; Li, Lei

2015-08-01

Eras encodes a Ras-like GTPase protein that was originally identified as an embryonic stem cell-specific Ras. ERAS has been known to be required for the growth of embryonic stem cells and stimulates somatic cell reprogramming, suggesting its roles on mouse early embryonic development. We now report a dynamic expression pattern of Eras during mouse peri-implantation development: its expression increases at the blastocyst stage, and specifically decreases in E7.5 mesoderm. In accordance with its expression pattern, the increased expression of Eras promotes cell proliferation through controlling AKT activation and the commitment from ground to primed state through ERK activation in mouse embryonic stem cells; and the reduced expression of Eras facilitates primitive streak and mesoderm formation through AKT inhibition during gastrulation. The expression of Eras is finely regulated to match its roles in mouse early embryonic development during which Eras expression is negatively regulated by the β-catenin pathway. Thus, beyond its well-known role on cell proliferation, ERAS may also play important roles in cell lineage specification during mouse early embryonic development. © 2015 The Authors.

Risk of death and myocardial infarction in patients with peripheral arterial disease undergoing percutaneous coronary intervention (from the National Heart, Lung and Blood Institute Dynamic Registry).

PubMed

Parikh, Shailja V; Saya, Shoaib; Divanji, Punag; Banerjee, Subhash; Selzer, Faith; Abbott, J Dawn; Naidu, Srihari S; Wilensky, Robert L; Faxon, David P; Jacobs, Alice K; Holper, Elizabeth M

2011-04-01

Patients with peripheral arterial disease (PAD) undergoing percutaneous coronary intervention (PCI) are at high risk for adverse cardiovascular events. Trends over time in outcomes with advances in PCI and medical therapy are unknown. We evaluated 866 patients with PAD in the National Heart, Lung, and Blood Institute (NHLBI) Dynamic Registry undergoing PCI according to treatment eras: the early bare metal stent (BMS) era (wave 1, 1997 to 1998, n = 180), the BMS era (waves 2 and 3, 1999 and 2001 to 2002, n = 339), and the drug-eluting stent (DES) era (waves 4 and 5, 2004 and 2006, n = 347). We compared in-hospital and 1-year outcomes by recruitment era. In-hospital coronary artery bypass graft surgery rates were significantly lower in the later eras (3.9%, 0.9%, and 0.6% for the early BMS, BMS, and DES eras, respectively, p for trend = 0.005), and an increasing percentage of patients were discharged on aspirin, β blockers, statins, and thienopyridines (p for trend <0.001 for all comparisons). Cumulative 1-year event rates in patients with PAD in the early BMS era, BMS era, and DES era for death were 13.7%, 10.5%, and 9.8% (p for trend = 0.21), those for myocardial infarction (MI) were 9.8%, 8.8%, and 10.0% (p for trend = 0.95), and those for repeat revascularization were 26.8%, 21.0%, and 17.2% (p for trend = 0.008). The 1-year adjusted hazard ratios of adverse events in patients with PAD using the early BMS era as the reference were 0.84 for death in the BMS era (95% confidence interval [CI] 0.46 to 1.55, p = 0.58) and 1.35 in the DES era (95% CI 0.71 to 2.56, p = 0.36), 0.89 for MI in the BMS era (95% CI 0.48 to 1.66, p = 0.72) and 1.02 in the DES era (95% CI 0.55 to 1.87, p = 0.95), and 0.63 for repeat revascularization in the BMS era (95% CI 0.41 to 0.97, p = 0.04) and 0.46 in the DES era (95% CI 0.29 to 0.73, p = 0.001). In conclusion, despite significant improvements in medical therapy and a decrease in repeat revascularization over time, patients with PAD who undergo PCI have a persistent high rate of death and MI. Copyright © 2011 Elsevier Inc. All rights reserved.

Development and psychometrics of the five item daily index in a psychiatric sample.

PubMed

Dyer, Kale; Hooke, Geoff; Page, Andrew C

2014-01-01

Effective treatment of affective disorders requires the ability to reliably monitor patient progress and outcome. The current study aimed to establish the Daily Index-5 (DI-5) as a psychometrically sound and clinically valid measure of treatment response in psychiatric care for use as a companion measure with the WHO Wellbeing Index (WHO-5; Bech et al., 1996. Psychother. Psychosom. 65, 183-190.). Eight hundred and ninety four consecutive inpatients and day-patients at a psychiatric facility completed the DI-5, WHO-5, SF-36 (Ware et al., 1993. SF-36 Health Survey: Manual and Interpretation Guide. The Health Institute, New England Medical Centre, Boston, MA.) and DASS-21 (Lovibond and Lovibond, 1995b. Manual for the Depression Anxiety Stress Scales. Psychology Foundation, Sydney, Australia.; Ware et al., 1993. SF-36 Health Survey: Manual and Interpretation Guide. The Health Institute, New England Medical Centre, Boston, MA.) routinely during treatment. The DI-5 was shown to be a measure with high reliability and validity. In addition criteria for clinically significant recovery are presented with an example implementation of a Clinical Significance Monitoring system. Finally, the latent structure of the DI-5 is established as a uni-dimensional index of affective disorder. The results may be generalized to samples with primary diagnoses of depressive and/or anxiety disorders though assessment of the DI-5 as a measure of treatment response is warranted in patients with other primary diagnoses. The current study indicates that the DI-5 is a quick to administer and interpret, reliable and valid measure for assessing patient outcome that is appropriate for use in monitoring patient change. © 2013 Published by Elsevier B.V.

Analysis of polyethylene wear in plain radiographs

PubMed Central

2009-01-01

Background and purpose Two-dimensional computerized radiographic techniques are frequently used to measure in vivo polyethylene (PE) wear after total hip arthroplasty (THA), and several variables in the clinical set-up may influence the amount of wear that is measured. We compared the repeatability and concurrent validity of linear PE wear on plain radiographs using the same software but a different number of radiographs. Methods We used either 1, 2, or 6 anteroposterior (AP) hip radiographs of 11 patients from a clinical THA series with 12 years of follow-up, and measured the PE wear with the software PolyWare 3D Pro. Repeatability within and concurrent validity between the different numbers of radiograph strategies were assessed using limits of agreement (LOAs) and bias. Results Observed median wear (range) in mm was 3.4 (1.6–4.6), 2.3 (0.7–4.9), and 4.0 (2.6–6.2) for the 1-, 2-, and 6-radiograph strategies. For repeatability, no bias (p > 0.41) was observed. LOAs around the bias were ± 0.6, ± 0.4, and ± 1.2 mm for the 1-, 2-, and 6-radiograph strategies. For concurrent validity, a bias (± LOA) between all pairwise comparisons was observed (p < 0.02) with 0.8 mm (± 2.5) between the 1- and 2-radiograph strategies, 1.0 mm (± 2.2) between the 1- and 6-radiograph strategies, and 1.8 mm (± 1.2) between the 2- and 6-radiograph strategies. Interpretation The number of radiographs used for wear measurement with a shadow-casting analysis method on plain AP radiographs influences the amount of linear wear measured. Results of PE wear obtained with PolyWare in studies using a different number of radiographs are not comparable. PMID:19995318

The Watershed and River Systems Management Program: Decision Support for Water- and Environmental-Resource Management

NASA Astrophysics Data System (ADS)

Leavesley, G.; Markstrom, S.; Frevert, D.; Fulp, T.; Zagona, E.; Viger, R.

2004-12-01

Increasing demands for limited fresh-water supplies, and increasing complexity of water-management issues, present the water-resource manager with the difficult task of achieving an equitable balance of water allocation among a diverse group of water users. The Watershed and River System Management Program (WARSMP) is a cooperative effort between the U.S. Geological Survey (USGS) and the Bureau of Reclamation (BOR) to develop and deploy a database-centered, decision-support system (DSS) to address these multi-objective, resource-management problems. The decision-support system couples the USGS Modular Modeling System (MMS) with the BOR RiverWare tools using a shared relational database. MMS is an integrated system of computer software that provides a research and operational framework to support the development and integration of a wide variety of hydrologic and ecosystem models, and their application to water- and ecosystem-resource management. RiverWare is an object-oriented reservoir and river-system modeling framework developed to provide tools for evaluating and applying water-allocation and management strategies. The modeling capabilities of MMS and Riverware include simulating watershed runoff, reservoir inflows, and the impacts of resource-management decisions on municipal, agricultural, and industrial water users, environmental concerns, power generation, and recreational interests. Forecasts of future climatic conditions are a key component in the application of MMS models to resource-management decisions. Forecast methods applied in MMS include a modified version of the National Weather Service's Extended Streamflow Prediction Program (ESP) and statistical downscaling from atmospheric models. The WARSMP DSS is currently operational in the Gunnison River Basin, Colorado; Yakima River Basin, Washington; Rio Grande Basin in Colorado and New Mexico; and Truckee River Basin in California and Nevada.

Master Middle Ware: A Tool to Integrate Water Resources and Fish Population Dynamics Models

NASA Astrophysics Data System (ADS)

Yi, S.; Sandoval Solis, S.; Thompson, L. C.; Kilduff, D. P.

2017-12-01

Linking models that investigate separate components of ecosystem processes has the potential to unify messages regarding management decisions by evaluating potential trade-offs in a cohesive framework. This project aimed to improve the ability of riparian resource managers to forecast future water availability conditions and resultant fish habitat suitability, in order to better inform their management decisions. To accomplish this goal, we developed a middleware tool that is capable of linking and overseeing the operations of two existing models, a water resource planning tool Water Evaluation and Planning (WEAP) model and a habitat-based fish population dynamics model (WEAPhish). First, we designed the Master Middle Ware (MMW) software in Visual Basic for Application® in one Excel® file that provided a familiar framework for both data input and output Second, MMW was used to link and jointly operate WEAP and WEAPhish, using Visual Basic Application (VBA) macros to implement system level calls to run the models. To demonstrate the utility of this approach, hydrological, biological, and middleware model components were developed for the Butte Creek basin. This tributary of the Sacramento River, California is managed for both hydropower and the persistence of a threatened population of spring-run Chinook salmon (Oncorhynchus tschawytscha). While we have demonstrated the use of MMW for a particular watershed and fish population, MMW can be customized for use with different rivers and fish populations, assuming basic data requirements are met. This model integration improves on ad hoc linkages for managing data transfer between software programs by providing a consistent, user-friendly, and familiar interface across different model implementations. Furthermore, the data-viewing capabilities of MMW facilitate the rapid interpretation of model results by hydrologists, fisheries biologists, and resource managers, in order to accelerate learning and management decision making.

Producing regionally-relevant multiobjective tradeoffs to engage with Colorado water managers

NASA Astrophysics Data System (ADS)

Smith, R.; Kasprzyk, J. R.; Basdekas, L.; Dilling, L.

2016-12-01

Disseminating results from water resources systems analysis research can be challenging when there are political or regulatory barriers associated with real-world models, or when a research model does not incorporate management context to which practitioners can relate. As part of a larger transdisciplinary study, we developed a broadly-applicable case study in collaboration with our partners at six diverse water utilities in the Front Range of Colorado, USA. Our model, called the "Eldorado Utility Planning Model", incorporates realistic water management decisions and objectives and achieves a pragmatic balance between system complexity and simplicity. Using the sophisticated modeling platform RiverWare, we modeled a spatially distributed regional network in which, under varying climate scenarios, the Eldorado Utility can meet growing demand from its variety of sources and by interacting with other users in the network. In accordance with complicated Front Range water laws, ownership, priority of use, and restricted uses of water are tracked through RiverWare's accounting functionality. To achieve good system performance, Eldorado can make decisions such as expand/build a reservoir, purchase rights from one or more actors, and enact conservation. This presentation introduces the model, and motivates how it can be used to aid researchers in developing multi-objective evolutionary algorithm (MOEA)-based optimization for similar multi-reservoir systems in Colorado and the Western US. Within the optimization, system performance is quantified by 5 objectives: minimizing time in restrictions; new storage capacity; newly developed supply; and uncaptured water; and maximizing year-end storage. Our results demonstrate critical tradeoffs between the objectives and show how these tradeoffs are affected by several realistic climate change scenarios. These results were used within an interactive workshop that helped demonstrate the application of MOEA-based optimization for water management in the western US.

An economic evaluation of the Enhanced Recovery After Surgery (ERAS) multisite implementation program for colorectal surgery in Alberta

PubMed Central

Thanh, Nguyen X.; Chuck, Anderson W.; Wasylak, Tracy; Lawrence, Jeannette; Faris, Peter; Ljungqvist, Olle; Nelson, Gregg; Gramlich, Leah M.

2016-01-01

Background In February 2013, Alberta Health Services established an Enhanced Recovery After Surgery (ERAS) implementation program for adopting the ERAS Society colorectal guidelines into 6 sites (initial phase) that perform more than 75% of all colorectal surgeries in the province. We conducted an economic evaluation of this initiative to not only determine its cost-effectiveness, but also to inform strategy for the spread and scale of ERAS to other surgical protocols and sites. Methods We assessed the impact of ERAS on patients’ health services utilization (HSU; length of stay [LOS], readmissions, emergency department visits, general practitioner and specialist visits) within 30 days of discharge by comparing pre- and post-ERAS groups using multilevel negative binomial regressions. We estimated the net health care costs/savings and the return on investment (ROI) associated with those impacts for post-ERAS patients using a decision analytic modelling technique. Results We included 331 pre- and 1295 post-ERAS patients in our analyses. ERAS was associated with a reduction in all HSU outcomes except visits to specialists. However, only the reduction in primary LOS was significant. The net health system savings were estimated at $2 290 000 (range $1 191 000–$3 391 000), or $1768 (range $920–$2619) per patient. The probability for the program to be cost-saving was 73%–83%. In terms of ROI, every $1 invested in ERAS would bring $3.8 (range $2.4–$5.1) in return. Conclusion The initial phase of ERAS implementation for colorectal surgery in Alberta is cost-saving. The total savings has the potential to be more substantial when ERAS is spread for other surgical protocols and across additional sites. PMID:28445024

Early-time cosmology with stiff era from modified gravity

NASA Astrophysics Data System (ADS)

Odintsov, S. D.; Oikonomou, V. K.

2017-11-01

In this work, we shall incorporate a stiff era in the Universe's evolution in the context of F (R ) gravity. After deriving the vacuum F (R ) gravity, which may realize a stiff evolution, we combine the stiff F (R ) gravity with an R2 model, and we construct a qualitative model for the inflationary and stiff era, with the latter commencing after the end of the inflationary era. We assume that the baryogenesis occurs during the stiff era, and we calculate the baryon to entropy ratio, which effectively constraints the functional form of the stiff F (R ) gravity. Further constraints on the stiff F (R ) gravity may come from the primordial gravitational waves, and particularly their scalar mode, which is characteristic of the F (R ) gravity theory. The stiff era presence does not contradict the standard cosmology era, namely, inflation, and the radiation-matter domination eras. Furthermore, we investigate which F (R ) gravity may realize a dust and stiff matter dominated Einstein-Hilbert evolution.

Vocational Education in Corrections. Information Series No. 237.

ERIC Educational Resources Information Center

Day, Sherman R.; McCane, Mel R.

Vocational education programs in America's correctional institutions have been financially handicapped, since security demands the greatest portion of resource allocations. Four eras in the development of the correctional system are generally identified: era of punishment and retribution, era of restraint or reform, era of rehabilitation and…

The Changing College Admissions Scene.

ERIC Educational Resources Information Center

Sjogren, Cliff

1983-01-01

Discusses the status of college admissions and some of the forces that influenced college admissions policies during each of four three-year periods: the Sputnik Era (1957-60), the Postwar Baby Boom Era (1964-67), the "New Groups" Era (1971-74), and the Stable Enrollment Era (1978-81). (PGD)

38 CFR 21.5020 - Post-Vietnam era veterans' educational assistance.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Post-Vietnam era veterans... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-Vietnam Era Veterans' Educational Assistance Under 38 U.S.C. Chapter 32 General § 21.5020 Post-Vietnam era veterans' educational assistance...

38 CFR 21.5020 - Post-Vietnam era veterans' educational assistance.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Post-Vietnam era veterans... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-Vietnam Era Veterans' Educational Assistance Under 38 U.S.C. Chapter 32 General § 21.5020 Post-Vietnam era veterans' educational assistance...

38 CFR 21.5020 - Post-Vietnam era veterans' educational assistance.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Post-Vietnam era veterans... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-Vietnam Era Veterans' Educational Assistance Under 38 U.S.C. Chapter 32 General § 21.5020 Post-Vietnam era veterans' educational assistance...

38 CFR 21.5020 - Post-Vietnam era veterans' educational assistance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Post-Vietnam era veterans... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-Vietnam Era Veterans' Educational Assistance Under 38 U.S.C. Chapter 32 General § 21.5020 Post-Vietnam era veterans' educational assistance...

38 CFR 21.5020 - Post-Vietnam era veterans' educational assistance.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Post-Vietnam era veterans... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-Vietnam Era Veterans' Educational Assistance Under 38 U.S.C. Chapter 32 General § 21.5020 Post-Vietnam era veterans' educational assistance...

Characterization of Gas-Hydrate Sediment: In Situ Evaluation of Hydrate Saturation in Pores of Pressured Sedimental Samples

NASA Astrophysics Data System (ADS)

Jin, Y.; Konno, Y.; Kida, M.; Nagao, J.

2014-12-01

Hydrate saturation of gas-hydrate bearing sediment is a key of gas production from natural gas-hydrate reservoir. Developable natural gas-hydrates by conventional gas/oil production apparatus almost exist in unconsolidated sedimental layer. Generally, hydrate saturations of sedimental samples are directly estimated by volume of gas generated from dissociation of gas hydrates in pore spaces, porosity data and volume of the sediments. Furthermore, hydrate saturation can be also assessed using velocity of P-wave through sedimental samples. Nevertheless, hydrate saturation would be changed by morphological variations (grain-coating, cementing and pore-filling model) of gas hydrates in pore spaces. Jin et al.[1,2] recently observed the O-H stretching bands of H2O molecules of methane hydrate in porous media using an attenuated total reflection IR (ATR-IR) spectra. They observed in situ hydrate formation/dissociation process in sandy samples (Tohoku Keisya number 8, grain size of ca. 110 μm). In this presentation, we present IR spectroscopy approach to in situ evaluation of hydrate saturation of pressured gas-hydrate sediments. This work was supported by funding from the Research Consortium for Methane Hydrate Resources in Japan (MH21 Research Consortium) planned by the Ministry of Economy, Trade and Industry (METI), Japan. [1] Jin, Y.; Konno, Y.; Nagao, J. Energy Fules, 2012, 26, 2242-2247. [2] Jin, Y.; Oyama, H.; Nagao, J. Jpn. J. Appl. Phys. 2009, 48, No. 108001.

Infrared view of Bangkok, Thailand

NASA Image and Video Library

1992-04-02

The Bight of Bangkok and the city of Bangkok, Thailand are visible in this west looking view. The city of Bangkok, with an estimated population in excess of 3.7 million people, can be seen in the lower right-hand corner of the view. The city, famous as a jewelry trading center, dealing in precious stones and silver and bronze ware, is situated in a vast lowland. This lowland is a major rice growing area interspersed with canals used for irrigation and drainage. Rice is a major export commodity of Thailand. The deforested hills of the Bilauktaung Range can be seen at the top of the view.

Accumulation of Background Impurities in Hydride Vapor Phase Epitaxy Grown GaN Layers

NASA Astrophysics Data System (ADS)

Usikov, Alexander; Soukhoveev, Vitali; Kovalenkov, Oleg; Syrkin, Alexander; Shapovalov, Liza; Volkova, Anna; Ivantsov, Vladimir

2013-08-01

We report on accumulation of background Si and O impurities measured by secondary ion mass spectrometry (SIMS) at the sub-interfaces in undoped, Zn- and Mg-doped multi-layer GaN structures grown by hydride vapor phase epitaxy (HVPE) on sapphire substrates with growth interruptions. The impurities accumulation is attributed to reaction of ammonia with the rector quartz ware during the growth interruptions. Because of this effect, HVPE-grown GaN layers had excessive Si and O concentration on the surface that may hamper forming of ohmic contacts especially in the case of p-type layers and may complicate homo-epitaxial growth of a device structure.

Crystallographic CourseWare

NASA Astrophysics Data System (ADS)

Kastner, Margaret E.; Vasbinder, Eric; Kowalcyzk, Deborah; Jackson, Sean; Giammalvo, Joseph; Braun, James; Dimarco, Keith

2000-09-01

Literature Cited

1. International Tables for Crystallography: Volume A: Space Group Symmetry; Hanh, T., Ed.; D. Reidel: Boston, 1983.
2. International Tables for Crystallography, Brief Teaching Edition of Volume A, Space-Group Symmetry, 3rd ed.; Hanh, T., Ed.; Dordrecht: Boston, 1993.
3. Kastner, M. E. J. Appl. Crystallogr. 1999, 32, 327-331.
4. Macromedia Director, version 6.5; Macromedia, Inc., San Francisco, CA; 1998.
5. QuickTime, version 3.0; Apple Computer: Cupertino, CA, 1998.
6. ToolBook II, Instructor, version 6.0; Asymetrix: Bellevue, WA, 1998.
7. HyperCard 2.3.5; Apple Computer: Cupertino, CA, 1998.

Optical Pumping of the Electronic and Nuclear Spin of Single Charge-Tunable Quantum Dots

DTIC Science & Technology

2005-02-02

Optical Pumping of the Electronic and Nuclear Spin of Single Charge-Tunable Quantum Dots A. S . Bracker,1 E. A. Stinaff,1 D. Gammon,1 M. E. Ware,1 J...G. Tischler,1 A. Shabaev,1 Al. L. Efros,1 D. Park,1 D. Gershoni,2 V. L. Korenev ,3 and I. A. Merkulov3 1Naval Research Laboratory, Washington, D.C...intensity (open circles), the PRL 94, 047402 (2005) P H Y S I C A L R E V I E W L E T T E R S week ending 4 FEBRUARY 2005 0031-9007=05=94(4)=047402(4

Adaptation of the Camera Link Interface for Flight-Instrument Applications

NASA Technical Reports Server (NTRS)

Randall, David P.; Mahoney, John C.

2010-01-01

COTS (commercial-off-the-shelf) hard ware using an industry-standard Camera Link interface is proposed to accomplish the task of designing, building, assembling, and testing electronics for an airborne spectrometer that would be low-cost, but sustain the required data speed and volume. The focal plane electronics were designed to support that hardware standard. Analysis was done to determine how these COTS electronics could be interfaced with space-qualified camera electronics. Interfaces available for spaceflight application do not support the industry standard Camera Link interface, but with careful design, COTS EGSE (electronics ground support equipment), including camera interfaces and camera simulators, can still be used.

Face Detection and Modeling for Recognition

DTIC Science & Technology

2002-01-01

gi st er ed ra n ge an d co lo r im ag es . 16 F ig u re 1. 12 . S y st em d ia gr...it h an d w it h ou t th e tr an sf or m ar e sh ow n . F or ea ch ex am p le , th e im ag es sh ow n in th e fi rs t co lu m n ar e sk in re gi on s...software/products /perflib/ipl/index.htm>. [187] Intel Open Source Computer Vision Library, <http://developer.intel.com/ soft- ware/opensource/cvfl/ opencv

Taking in a Show.

PubMed

Boden, Timothy W

2016-01-01

Many medical practices have cut back on education and staff development expenses, especially those costs associated with conventions and conferences. But there are hard-to-value returns on your investment in these live events--beyond the obvious benefits of acquired knowledge and skills. Major vendors still exhibit their services and wares at many events, and the exhibit hall is a treasure-house of information and resources for the savvy physician or administrator. Make and stick to a purposeful plan to exploit the trade show. You can compare products, gain new insights and ideas, and even negotiate better deals with representatives anxious to realize returns on their exhibition investments.

Noninvasive express diagnostics of pulmonary diseases based on control of patient's gas emission using methods of IR and terahertz laser spectroscopy

NASA Astrophysics Data System (ADS)

Starikova, M. K.; Bulanova, A. A.; Bukreeva, E. B.; Karapuzikov, A. A.; Karapuzikov, A. I.; Kistenev, Y. V.; Klementyev, V. M.; Kolker, D. B.; Kuzmin, D. A.; Nikiforova, O. Y.; Ponomarev, Yu. N.; Sherstov, I. V.; Boyko, A. A.

2013-11-01

Pulmonary diseases diagnostics always occupies one of the key positions in medicine practices. A large variety of high technology methods are used today, but none of them cannot be used for early screening of pulmonary diseases. We discuss abilities of methods of IR and terahertz laser spectroscopy for noninvasive express diagnostics of pulmonary diseases on a base of analysis of absorption spectra of patient's gas emission, in particular, exhaled air. Experience in the field of approaches to experimental data analysis and hard-ware realization of gas analyzers for medical applications is also discussed.

Expectations Regarding Aging, Physical Activity, and Physical Function in Older Adults

PubMed Central

Breda, Aili I.; Watts, Amber S.

2017-01-01

Objective: The present study examined how expectations regarding aging (ERA) influence physical activity participation and physical function. Method: We surveyed 148 older adults about their ERA (ERA-38), health-promoting lifestyles (HPLP-II), and self-rated health (RAND-36). We tested the mediating effect of physical activity on the relationships between ERA and physical function. Results: Positive expectations were associated with more engagement in physical activity (B = 0.016, p < .05) and better physical function (B = 0.521, p < .01). Physical activity mediated the relationship between ERA and physical function (B = 5.890, p < .01, indirect effect 0.092, CI = [0.015, 0.239]). Discussion: ERA play an important role in adoption of physically active lifestyles in older adults and may influence health outcomes, such as physical function. Future research should evaluate whether attempts to increase physical activity are more successful when modifications to ERA are also targeted. PMID:28491915

77 FR 12080 - Era Systems, LLC, Formerly Era Systems Corporation, a Subsidiary of Systems Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-28

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,047] Era Systems, LLC, Formerly Era Systems Corporation, a Subsidiary of Systems Research and Applications Corporation, Syracuse, NY; Notice of Affirmative Determination Regarding Application for Reconsideration By application dated February 2, 2012, a worker requested...

The Vietnam Era Veteran: Challenge for Change. Administrator's Seminars on Vietnam Era Veterans.

ERIC Educational Resources Information Center

Veterans Administration, Washington, DC.

This report covers 5 regional seminars designed to increase the Veterans Administration understanding of Vietnam Era veterans. The process used was one of involvement and interaction of Veterans Administration officials with returning Vietnam Era veterans and other young people. After the traditional introductions and keynote remarks, there was a…

Validity and reliability of the expectations regarding aging (ERA-12) instrument among middle-aged Singaporeans.

PubMed

Joshi, Veena D; Malhotra, Rahul; Lim, Jeremy F Y; Østbye, Truls; Wong, Michael

2010-05-01

The 12-item Expectations Regarding Aging (ERA-12) instrument measures expectations that individuals have about how their health and cognitive function will be when they age. To date, primarily assessed among older adults in Western settings, expectations regarding ageing have been associated with physical activity and healthcare seeking behaviour. It has been suggested that it may be possible to develop interventions that promote positive expectations about ageing. Assessment of expectations regarding ageing among today's middle-aged population would allow for earlier interventions to help give them positive (but realistic) ageing expectations, and age successfully. We assess the reliability and validity of ERA-12 for middle-aged Singaporeans. A questionnaire that included ERA-12 was administered to 1020 patients aged 41 to 62 years attending 2 SingHealth polyclinics in Singapore. Data from 981 respondents who completed the ERA-12 instrument were analysed. ERA-12's construct validity was determined using Exploratory Factor Analysis (EFA), and through its correlation with depressive symptoms, and self-rated health and education. Internal consistency reliability was assessed using Cronbach's alpha. EFA confirmed that the ERA-12 consisted of 3 factors (each with 4 items)--expectations regarding physical health, mental health and cognitive function, together explaining 64% of the variance in ERA-12 total score with high factor loadings (range, 0.6 to 0.8). The ERA-12 total score was positively correlated with self-rated health (r = 0.13) and education (r = 0.19), and negatively correlated with depressive symptoms (r = -0.25). Cronbach's alpha exceeded 0.7 for ERA-12 overall, and for each subscale. ERA-12 can be used to evaluate expectations regarding ageing not only among elderly populations in the West, but also among middle-aged Singaporeans.

Changing trends in prognostic factors for patients with multiple myeloma after autologous stem cell transplantation during the immunomodulator drug/proteasome inhibitor era

PubMed Central

Takamatsu, Hiroyuki; Honda, Sumihisa; Miyamoto, Toshihiro; Yokoyama, Kenji; Hagiwara, Shotaro; Ito, Toshiro; Tomita, Naoto; Iida, Shinsuke; Iwasaki, Toshihiro; Sakamaki, Hisashi; Suzuki, Ritsuro; Sunami, Kazutaka

2015-01-01

We evaluated the clinical significance of prognostic factors including the International Staging System (ISS) and modified European Group for Blood and Marrow Transplantation response criteria in 1650 Japanese patients with multiple myeloma (MM) who underwent upfront single autologous stem cell transplantation (ASCT). We categorized patients into two treatment cohorts: pre-novel agent era (1995–2006) and novel agent era (2008–2011). The combined percentage of pre-ASCT complete response and very good partial response cases (463 of 988, 47%) significantly increased during the novel agent era compared with the pre-novel agent era (164 of 527, 31%; P < 0.0001). The 2-year overall survival (OS) rate of 87% during the novel agent era was a significant improvement relative to that of 82% during the pre-novel agent era (P = 0.019). Although significant differences in OS were found among ISS stages during the pre-novel agent era, no significant difference was observed between ISS I and II (P = 0.107) during the novel agent era. The factors independently associated with a superior OS were female gender (P = 0.002), a good performance status (P = 0.024), lower ISS (P < 0.001), pre-ASCT response at least partial response (P < 0.001) and ASCT during the novel agent era (P = 0.017). These results indicate that the response rate and OS were significantly improved, and the ISS could not clearly stratify the prognoses of Japanese patients with MM who underwent upfront single ASCT during the novel agent era. PMID:25530023

Improving National Results in Liver Transplantation Using Grafts From Donation After Cardiac Death Donors.

PubMed

Croome, Kristopher P; Lee, David D; Keaveny, Andrew P; Taner, C Burcin

2016-12-01

Published reports describing the national experience with liver grafts from donation after cardiac death (DCD) donors have resulted in reservations with their widespread utilization. The present study aimed to investigate if temporal improvements in outcomes have been observed on a national level and to determine if donor and recipient selection have been modified in a fashion consistent with published data on DCD use in liver transplantation (LT). Patients undergoing DCD LT between 2003 and 2014 were obtained from the United Network of Organ Sharing Standard Transplant Analysis and Research file and divided into 3 equal eras based on the date of DCD LT: era 1 (2003-2006), era 2 (2007-2010), and era 3 (2011-2014). Improvement in graft survival was seen between era 1 and era 2 (P = 0.001) and between era 2 and era 3 (P < 0.001). Concurrently, an increase in the proportion of patients with hepatocellular carcinoma and a decrease in critically ill patients, retransplant recipients, donor age, warm ischemia time greater than 30 minutes and cold ischemic time also occurred over the same period. On multivariate analysis, significant predictors of graft survival included: recipient age, biologic MELD score, recipient on ventilator, recipient hepatitis C virus + serology, donor age and cold ischemic time. In addition, even after adjustment for all of the aforementioned variables, both era 2 (hazard ratio, 0.81; confidence interval, 0.69-0.94; P = 0.007), and era 3 (hazard ratio, 0.61; confidence interval, 0.5-0.73; P < 0.001) had a protective effect compared to era 1. The national outcomes for DCD LT have improved over the last 12 years. This change was associated with modifications in both recipient and donor selection. Furthermore, an era effect was observed, even after adjustment for all recipient and donor variables on multivariate analysis.

The evolution of anterior sector venous drainage in right lobe living donor liver transplantation: does one technique fit all?

PubMed Central

Tokat, Yaman

2016-01-01

In living donor liver transplantation (LDLT), an adequate hepatic venous outflow constitutes one of the basic principles of a technically successful procedure. The issue of whether the anterior sector (AS) of the right lobe (RL) graft should or should not be routinely drained has been controversial. The aim of this 10-year, single-center, retrospective cohort study was to review the evolution of our hepatic venous outflow reconstruction technique in RL grafts and evaluate the impact of routine AS drainage strategy on the outcome. The study group consisted of 582 primary RL LDLT performed between July 2004 and December 2014. The cases were divided into 3 consecutive periods with different AS venous outflow reconstruction techniques, which included middle hepatic vein (MHV) drainage in Era 1 (n=119), a more selective AS drainage with cryopreserved homologous grafts in Era 2 (n=391), and routine segment 5 and/or 8 oriented AS drainage with synthetic grafts in Era 3 (n=72). Intraoperative portal flow measurement with routine splenic artery ligation (SAL) technique (in RL grafts with a portal flow of ≥ 250 mL/min/100 g liver tissue) was added later in Era 3. These 3 groups were compared in terms of recipient and donor demographics, surgical characteristics and short-term outcome. The rate of AS venous drainage varied from 58.8% in Era 1 and 35.0% in Era 2 to 73.6% in Era 3 (P<0.001). Perioperative mortality rate of recipients significantly decreased over the years (15.1% in Era 1 and 8.7% in Era 2 vs. 2.8% in Era 3, P=0.01). After the addition of SAL technique in the 45 cases, there was only 1 graft loss and no perioperative mortality. One-year recipient survival rate was also significantly higher in Era 3 (79.6% in Era 1 and 86.1% in Era 2 vs. 92.1% in Era 3, P=0.002). Routine AS drainage via segment 5 and/or 8 veins using synthetic grafts is a technique to fit all RL grafts in LDLT. Addition of SAL effectively prevents early graft dysfunction and significantly improves the outcome. PMID:27115010

A History of Sex Education in the United States since 1900

ERIC Educational Resources Information Center

Huber, Valerie J.; Firmin, Michael W.

2014-01-01

We provide a historical perspective toward the current public school practices of American sex education. The primary time frames include the progressive era (1880-1920), intermediate era (1920-1960), the sexual revolution era (1960s and 1970s), and the modern sex education era (1980s to the present). In each period, we highlight key developments…

[The development of the Japanese pharmaceutical industry (part 7). Histories of medical advertisements from Taisho Era till Showa Era].

PubMed

Takehara, J; Yamada, H

1999-01-01

Medical advertisements in newspapers have been used quite often as a means of sales promotion since the Meiji Era. Medical advertisements were quantitatively the leading advertisements in Japanese newspapers from the Taisho Era to early in the Showa Era. When World War II broke out, the quanity of advertisements in newspapers decreased markedly. After the war ended, the quantity of radio commercials for medicine increased quite rapidly. In the 1960s, however, pharmaceutical companies were criticized for over-promoting and improperly using medicines.

Conductivity and structure of ErAs nanoparticles embedded in GaAs pn junctions analyzed via conductive atomic force microscopy

NASA Astrophysics Data System (ADS)

Park, K. W.; Dasika, V. D.; Nair, H. P.; Crook, A. M.; Bank, S. R.; Yu, E. T.

2012-06-01

We have used conductive atomic force microscopy to investigate the influence of growth temperature on local current flow in GaAs pn junctions with embedded ErAs nanoparticles grown by molecular beam epitaxy. Three sets of samples, one with 1 ML ErAs deposited at different growth temperatures and two grown at 530 °C and 575 °C with varying ErAs depositions, were characterized. Statistical analysis of local current images suggests that the structures grown at 575 °C have about 3 times thicker ErAs nanoparticles than structures grown at 530 °C, resulting in degradation of conductivity due to reduced ErAs coverage. These findings explain previous studies of macroscopic tunnel junctions.

Biliary atresia: the Canadian experience.

PubMed

Schreiber, Richard A; Barker, Collin C; Roberts, Eve A; Martin, Steven R; Alvarez, Fernando; Smith, Lesley; Butzner, J Decker; Wrobel, Iwona; Mack, David; Moroz, Stanley; Rashid, Mohsin; Persad, Rabin; Levesque, Dominique; Brill, Herbert; Bruce, Garth; Critch, Jeff

2007-12-01

To determine the outcomes of Canadian children with biliary atresia. Health records of infants born in Canada between January 1, 1985 and December 31, 1995 (ERA I) and between January 1, 1996 and December 31, 2002 (ERA II) who were diagnosed with biliary atresia at a university center were reviewed. 349 patients were identified. Median patient age at time of the Kasai operation was 55 days. Median age at last follow-up was 70 months. The 4-year patient survival rate was 81% (ERA I = 74%; ERA II = 82%; P = not significant [NS]). Kaplan-Meier survival curves for patients undergoing the Kasai operation at age < or = 30, 31 to 90, and > 90 days showed 49%, 36%, and 23%, respectively, were alive with their native liver at 4 years (P < .0001). This difference continued through 10 years. The 2- and 4-year post-Kasai operation native liver survival rates were 47% and 35% for ERA I and 46% and 39% for ERA II (P = NS). A total of 210 patients (60%) underwent liver transplantation; the 4-year transplantation survival rate was 82% (ERA I = 83%, ERA II = 82%; P = NS). This is the largest outcome series of North American children with biliary atresia at a time when liver transplantation was available. Results in each era were similar. Late referral remains problematic; policies to ensure timely diagnosis are required. Nevertheless, outcomes in Canada are comparable to those reported elsewhere.

Changing Management of the Patent Ductus Arteriosus: Effect on Neonatal Outcomes and Resource Utilization.

PubMed

Chock, Valerie Y; Goel, Veena V; Palma, Jonathan P; Luh, Thomas M; Wang, Nichole A; Gaskari, Shabnam; Punn, Rajesh; Silverman, Norman H; Benitz, William E

2017-08-01

Objective  This historical cohort study investigated how a shift toward a more conservative approach of awaiting spontaneous closure of the patent ductus arteriosus (PDA) in preterm infants has affected neonatal outcomes and resource utilization. Methods  We retrospectively studied very low birth weight infants diagnosed with a PDA by echocardiogram (ECHO) in 2006-2008 (era 1), when medical or surgical PDA management was emphasized, to those born in 2010-2012 (era 2) when conservative PDA management was encouraged. Multiple regression analyses adjusted for gestational age were performed to assess differences in clinical outcomes and resource utilization between eras. Results  More infants in era 2 (35/89, 39%) compared with era 1 (22/120, 18%) had conservative PDA management ( p  < 0.01). Despite no difference in surgical ligation rate, infants in era 2 had ligation later (median 24 vs. 8 days, p  < 0.0001). There was no difference in clinical outcomes between eras, while number of ECHOs per patient was the only resource measure that increased in era 2 (median 3 vs. 2 ECHOs, p  = 0.003). Conclusion  In an era of more conservative PDA management, no increase in adverse clinical outcomes or significant change in resource utilization was found. Conservative PDA management may be a safe alternative for preterm infants. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Empowerment of Teachers in Implementing Thematic Learning Method

ERIC Educational Resources Information Center

Istiningsih

2017-01-01

The way of looking at something in the present era is different from the past era. In the past era, something is looked at partially. The effect of this situation is harm for the life. At present era and the future, look at something should comprehensively and integral. The profile of human beings who are able to think comprehensively and integral…

Marine ecological risk assessment methods for radiation accidents.

PubMed

Ye, Sufen; Zhang, Luoping; Feng, Huan

2017-12-01

Ecological risk assessment (ERA) is a powerful technical tool that can be used to analyze potential and extreme adverse environmental impacts. With the rapid development of nuclear power plants in coastal areas around the world, the establishment of approaches and methodologies for marine ERA with a focus on radiation accidents is an urgent requirement for marine environmental management. In this study, the approaches and methodologies for ERA pertaining to marine radiation accidents (MRA) are discussed and summarized with applications in case studies, such as the nuclear accident in Fukushima, Japan, and a hypothetical accident in Daya Bay, China. The concepts of ERA and Risk Degree of ERA on MRA are defined for the first time to optimize the ERA system. The results of case studies show that the ERA approach and methodology for MRA are scientifically sound and effective in both the early and late stage of MRAs along with classic ERA Approach and the ERICA Integrated Approach. The results can be useful in the decision-making processes and the risk management at the beginning of accident as well as the ecological restoration after the accident. Copyright © 2017 Elsevier Ltd. All rights reserved.

Study on the elemental features of ancient Chinese white porcelain at Jingdezhen by INAA

NASA Astrophysics Data System (ADS)

Xie, Guoxi; Feng, Songlin; Feng, Xiangqian; Li, Yongqiang; Han, Hongye; Wang, Yanqing; Zhu, Jihao; Yan, Lingtong; Li, Li

2009-03-01

Shards of ancient Chinese white porcelain, which were excavated at Maojiawan in the city of Beijing, were analyzed by instrumental neutron activation analysis (INAA). These shards were fired in the period between the Yuan (AD 1271-1368) and Ming (AD 1368-1644) dynasties at Jingdezhen in southern China. According to the analytical results, different raw materials were used for making porcelain body in this period. Fe and Na are the characteristic elements which can be used for identifying the specific date of these porcelains. Furthermore, shards of Hongwu era (AD 1368-1398), Yongle-Xuande era (AD 1403-1435) and Chenghua-Zhengde era (AD 1465-1561) of the Ming dynasty can be clearly distinguished by their elemental body composition. The temporal chemical variation in the porcelain body of these eras is observed. The elemental body composition of Zhengde-Tianshun era (AD 1436-1464) is mainly similar to that of the Hongwu and Yongle-Xuande eras. The temporal chemical feature of Zhengtong-Tianshun era was not found.

Recommended Capacities for Educational Leadership: Pre-Reform Era Scholars versus Reform-Era Scholars versus National Standards

ERIC Educational Resources Information Center

Gordon, Stephen P.; Taylor-Backor, Karen; Croteau, Susan

2017-01-01

We reviewed the scholarship on capacities for educational leadership for the past decade of the pre-reform era (1976-1985), as well as a recent decade of the reform era (2005-2015), and compared scholarship from both decades with the current Professional Standards for Educational Leaders. We found that scholars in the past decade of the pre-reform…

The Nomadic Existence of the Eternal Improviser and Diasporic Co-Poiesis in the Era of Mega-Speed

ERIC Educational Resources Information Center

Gurze'ev, Ilan

2010-01-01

The history of transcendence and nomadism in face of the call for "home-returning" is marked figuratively by four milestones: (1) the "era" of immanence and dwelling in total harmony as a manifestation of self-sustained holiness; (2) the "era" of relating to holiness by mediation of God, especially in the monotheistic religions; (3) the "era" of…

Surgical mentors' and mentees' productivity from 1993 to 2006.

PubMed

Orandi, Babak J; Blackburn, Susan; Henke, Peter K

2011-02-01

Mentorship in academic surgery is reflected in part by senior surgeon support of younger individuals with their scholarly contributions to the literature. Scholarship is also reflected in the procurement of extramural funding. This study sought to quantify this process in recent years. All active American Surgical Association and Society of University Surgeons members in the following 2 eras were defined as being mentors (N = 559): 1993 to 1999 (I) and 2000 to 2006 (II). Mentees (N = 7,037) were defined as a primary author associated with the mentor. MEDLINE-cited papers of mentors and mentees were abstracted. Randomly selected mentees from era I and II were examined for academic productivity. The National Institutes of Health (NIH) Computer Retrieval of Information on Scientific Projects database was queried for federal research funding for the mentors and mentees. Continuous categoric and logistical regression was used as appropriate. Combining both eras, mentors published a total of 23,558 articles, of which 3,854 were primary and 9,881 were senior authored. Mentor primary-authored papers were more common in era I than era II (mean = 8 vs 6 articles, P < .01), whereas the number of senior-authored papers was similar in both eras (mean = 18 vs 17 papers, P = .09). Fewer mentors had federal funding in era I compared with era II (42% vs 51%, P = .04). More mentees per mentor existed in era I compared with era II (15 ± 5 vs 9 ± 4, P < .001). Era I mentees examined in era II (n = 187) were primary and senior author of a mean of 2.5 and 5 articles, respectively. Of this group, 14 (7.5%) had federal funding. The number of primary- and senior-authored articles from the mentee but not their prior mentor correlated with federal funding (P < .05). The number of mentees per mentor has decreased in recent years as has primary-authored authors, whereas federal funding has increased for mentors. Overall NIH funding for mentees was low but is related to their productivity with the mentor. Copyright © 2011 Elsevier Inc. All rights reserved.

The pros and cons of ecological risk assessment based on data from different levels of biological organization

PubMed Central

Rohr, Jason R.; Salice, Christopher J.; Nisbet, Roger M.

2016-01-01

Ecological risk assessment (ERA) is the process used to evaluate the safety of manufactured chemicals to the environment. Here we review the pros and cons of ERA across levels of biological organization, including suborganismal (e.g. biomarkers), individual, population, community, ecosystem, and landscapes levels. Our review revealed that level of biological organization is often related negatively with ease at assessing cause-effect relationships, ease of high-throughput screening of large numbers of chemicals (it is especially easier for suborganismal endpoints), and uncertainty of the ERA because low levels of biological organization tend to have a large distance between their measurement (what is quantified) and assessment endpoints (what is to be protected). In contrast, level of biological organization is often related positively with sensitivity to important negative and positive feedbacks and context dependencies within biological systems, and ease at capturing recovery from adverse contaminant effects. Some endpoints did not show obvious trends across levels of biological organization, such as the use of vertebrate animals in chemical testing and ease at screening large numbers of species, and other factors lacked sufficient data across levels of biological organization, such as repeatability, variability, cost per study, and cost per species of effects assessment, the latter of which might be a more defensible way to compare costs of ERAs than cost per study. To compensate for weaknesses of ERA at any particular level of biological organization, we also review mathematical modeling approaches commonly used to extrapolate effects across levels of organization. Finally, we provide recommendations for next generation ERA, submitting that if there is an ideal level of biological organization to conduct ERA, it will only emerge if ERA is approached simultaneously from the bottom of biological organization up as well as from the top down, all while employing mathematical modeling approaches where possible to enhance ERA. Because top-down ERA is unconventional, we also offer some suggestions for how it might be implemented efficaciously. We hope this review helps researchers in the field of ERA fill key information gaps and helps risk assessors identify the best levels of biological organization to conduct ERAs with differing goals. PMID:27340745

[Assessing the Current Status of Enhanced Recovery after Surgery in the Usage of Web-based Survey Questionnaires by Thoracic Surgeons and Nurses Attending the Meeting in Mainland China].

PubMed

Du, Na; Guo, Chenglin; Yang, Mei; Ji, Yanli; Wang, Wei; Li, Jie; Li, Chuan; Liu, Lunxu; Che, Guowei

2017-03-20

Though the concept of enhanced recovery after surgery (ERAS) has been progressively known by the surgeons and applied clinically, the current status of its cognition among thoracic surgeons and application in thoracic surgery is still unknown. Based on the analysis of a survey of thoracic surgeons and nurses on chest ERAS during a national conference, we aimed to analyze the status and difficulties of the application of ERAS in thoracic surgery. A total of 773 questionnaires were collected during the first West China chest ERAS Forum and analyzed. The content of the questionnaire can be divided into two parts, including the respondents' institute and personal information, 10 questions on ERAS. (1) Current status of clinical application of ERAS is the concept rather than the practice: 69.6% of the surgeons and 58.7% of the nurses agreed with this view; in addition, 88.5% of the doctors and 85.7% of the nurses believed that the concept of ERAS may be applicable to every branches of surgery; (2) 55.6% of the doctors and 69.1% of the nurses believed that the reason of poor clinical application of ERAS included no mature procedure, lack of consensus and specifications; (3) The best team for the clinical practice of ERAS should be based on surgeon-centered multidisciplinary cooperation and integration of medical care: 62.1% of the surgeons and 70.7% of nurses agreed with this view; (4) 73.7% of the surgeons and 81.9% of the nurses agreed that mean hospital stay, patients' experience in hospital and social satisfaction should be the evaluation standard of ERAS practice. The application of ERAS in thoracic surgery is still the concept rather than the practice. The reason included the lack of clinical applicable specifications and scheme.

Enhanced recovery care versus traditional care after laparoscopic liver resections: a randomized controlled trial.

PubMed

Liang, Xiao; Ying, Hanning; Wang, Hongwei; Xu, Hongxia; Liu, Minjun; Zhou, Haiyan; Ge, Huiqing; Jiang, Wenbin; Feng, Lijun; Liu, Hui; Zhang, Yingchun; Mao, Zhiying; Li, Jianhua; Shen, Bo; Liang, Yuelong; Cai, Xiujun

2018-06-01

Enhanced recovery after surgery (ERAS), with several evidence-based elements, has been shown to shorten length of hospital stay and reduce perioperative hospital costs in many operations. This randomized clinical trial was performed to compare complications and hospital stay of laparoscopic liver resection between ERAS and traditional care. A randomized controlled trial was performed for laparoscopic liver resection from August 2015 to August 2016. Patients were randomly divided into ERAS group and traditional care group. The primary outcome was length of hospital stay (LOS) after surgery. Second outcomes included postoperative complications, hospital cost, and 30-day readmissions. Elements used in ERAS group included more perioperative education, nurse navigators, nutrition support for liver diseases, respiratory therapy, oral carbohydrate 2 h before operation, early mobilization and oral intake, goal-directed fluid therapy, less drainages, postoperative nausea and vomiting (PONV) prophylaxis and multimodal analgesia. The study included 58 (two conversion to laparotomy) patients in ERAS group and 61 (three conversion to laparotomy) patients in the traditional care group. Postoperative LOS was significantly shorter in the ERAS group than traditional care group (5 vs. 8 days; p < 0.001). ERAS program significantly reduced the hospital costs (CNY 45413.1 vs. 55794.1; p = 0.006) and complications (36.2 vs. 55.7%; p = 0.033). Duration till first flatus and PONV were significantly reduced in ERAS group. Pain control was better in ERAS (Visual analogue scale (VAS) POD1 (≥ 4) 19.0 vs. 39.3%, p = 0.017; VAS POD1 2.5 vs. 3.1, p = 0.010). There was no difference in the rate of 30-day readmissions (6.9 vs. 8.2%; p = 1.000). ERAS protocol is feasible and safe for laparoscopic liver resection. Patients in ERAS group have less pain and complications.

Transversus Abdominis Plane Blockade as Part of a Multimodal Postoperative Analgesia Plan in Patients Undergoing Radical Cystectomy.

PubMed

Matulewicz, Richard S; Patel, Mehul; Jordan, Brian J; Morano, Jacqueline; Frainey, Brendan; Bhanji, Yasin; Bux, Mahreen; Nader, Antoun; Kundu, Shilajit D; Meeks, Joshua J

2018-04-26

Radical cystectomy (RC) is a morbid procedure with frequent complications that may benefit from implementation of an enhanced recovery after surgery (ERAS) protocol. To examine the benefits of a multimodal analgesic plan that uses continuous transversus abdominis plane (TAP) blockade as part of an ERAS protocol after RC. A retrospective comparison of consecutive patients undergoing RC over a 4-year period was conducted. Patients were designated as having surgery either before or after implementation of an ERAS protocol. A major component of the ERAS protocol was a multi-modal analgesia plan with TAP blockade. Patient demographics, comorbidities, operative details, and outcomes, including days to flatus, bowel movement (BM), narcotic usage, and length of stay (LOS) were compared. In total, 171 patients were included: 100 pre-ERAS and 71 ERAS. There were no differences in age, smoking status, operative approach, or diversion type. The patients in the ERAS cohort were less likely to be male, had a higher median BMI, and more likely to have received neoadjuvant chemotherapy. Total and early postoperative narcotic use were lower in the ERAS cohort: 89 vs. 336 mg ( p  < 0.001) and 62 vs 203 mg ( p  = 0.001), respectively. The ERAS cohort had fewer days to flatus (3 vs. 4, p  < 0.001) and fewer days to bowel movement (4 vs. 5, p  < 0.001). Median LOS was shorter in the ERAS cohort (7 vs. 8.5d, p  = 0.001). There were no differences in complications or readmission rates between the two cohorts. TAP blockade as part of an ERAS multi-modal pain plan is associated with low narcotic usage, and significant improvement in time to flatus, BM, and LOS compared to traditional post-RC pain management.

An investigation into the nutritional status of patients receiving an Enhanced Recovery After Surgery (ERAS) protocol versus standard care following Oesophagectomy.

PubMed

Benton, Katie; Thomson, Iain; Isenring, Elisabeth; Mark Smithers, B; Agarwal, Ekta

2018-06-01

Enhanced Recovery After Surgery (ERAS) protocols have been effectively expanded to various surgical specialities including oesophagectomy. Despite nutrition being a key component, actual nutrition outcomes and specific guidelines are lacking. This cohort comparison study aims to compare nutritional status and adherence during implementation of a standardised post-operative nutritional support protocol, as part of ERAS, compared to those who received usual care. Two groups of patients undergoing resection of oesophageal cancer were studied. Group 1 (n = 17) underwent oesophagectomy between Oct 2014 and Nov 2016 during implementation of an ERAS protocol. Patients in group 2 (n = 16) underwent oesophagectomy between Jan 2011 and Dec 2012 prior to the implementation of ERAS. Demographic, nutritional status, dietary intake and adherence data were collected. Ordinal data was analysed using independent t tests, and categorical data using chi-square tests. There was no significant difference in nutrition status, dietary intake or length of stay following implementation of an ERAS protocol. Malnutrition remained prevalent in both groups at day 42 post surgery (n = 10, 83% usual care; and n = 9, 60% ERAS). A significant difference was demonstrated in adherence with earlier initiation of oral free fluids (p <0.008), transition to soft diet (p <0.004) and continuation of jejunostomy feeds on discharge (p <0.000) for the ERAS group. A standardised post-operative nutrition protocol, within an ERAS framework, results in earlier transition to oral intake; however, malnutrition remains prevalent post surgery. Further large-scale studies are warranted to examine individualised decision-making regarding nutrition support within an ERAS protocol.

Women veterans' healthcare delivery preferences and use by military service era: findings from the National Survey of Women Veterans.

PubMed

Washington, Donna L; Bean-Mayberry, Bevanne; Hamilton, Alison B; Cordasco, Kristina M; Yano, Elizabeth M

2013-07-01

The number of women Veterans (WVs) utilizing the Veterans Health Administration (VA) has doubled over the past decade, heightening the importance of understanding their healthcare delivery preferences and utilization patterns. Other studies have identified healthcare issues and behaviors of WVs in specific military service eras (e.g., Vietnam), but delivery preferences and utilization have not been examined within and across eras on a population basis. To identify healthcare delivery preferences and healthcare use of WVs by military service era to inform program design and patient-centeredness. Cross-sectional 2008-2009 survey of a nationally representative sample of 3,611 WVs, weighted to the population. Healthcare delivery preferences measured as importance of selected healthcare features; types of healthcare services and number of visits used; use of VA or non-VA; all by military service era. Military service era differences were present in types of healthcare used, with World War II and Korea era WVs using more specialty care, and Vietnam era-to-present WVs using more women's health and mental health care. Operations Enduring Freedom, Iraqi Freedom, New Dawn (OEF/OIF/OND) WVs made more healthcare visits than WVs of earlier military eras. The greatest healthcare delivery concerns were location convenience for Vietnam and earlier WVs, and cost for Gulf War 1 and OEF/OIF/OND WVs. Co-located gynecology with general healthcare was also rated important by a sizable proportion of WVs from all military service eras. Our findings point to the importance of ensuring access to specialty services closer to home for WVs, which may require technology-supported care. Younger WVs' higher mental health care use reinforces the need for integration and coordination of primary care, reproductive health and mental health care.

Energy Research Abstracts. [DOE abstract journal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1981-01-01

Energy Research Abstracts (ERA) provides abstracting and indexing coverage of all scientific and technical reports, journal articles, conference papers and proceedings, books, patents, theses, and monographs originated by the US Department of Energy, its laboratories, energy centers, and contractors. ERA also covers other energy information prepared in report form by federal and state government organizations, foreign governments, and domestic and foreign universities and research organizations. ERA coverage of non-report literature is limited to that generated by Department of Energy activity. ERA is comprehensive in its subject scope, encompassing the DOE's research, development, demonstration, and technological programs resulting from its broadmore » charter for energy sources, conservation, safety, environmental impacts, and regulation. Corporate, author, subject, report number, and contract number indexes are included. ERA is available on an exchange basis to universities, research intitutions, industrial firms, and publishers of scientific information. Federal, state, and municipal agencies concerned with energy development, conservation, and usage may obtain ERA free of charge. Inquiries should be directed to the Technical Information Center, P.O. Box 62, Oak Ridge, Tennessee 37830. ERA is available to the public on a subscription basis for 24 semimonthly issues including a semiannual index and an annual index. All citations announced in ERA exist as separate records in the DOE Energy Data Base.« less

SPECIAL SECTION: Perspectives of the Scientific Community on the Status of Ecological Risk Assessment

PubMed

Power; Adams

1997-11-01

/ Views from a wide variety of practicing environmental professionals on the current status of ecological risk assessment (ERA) indicate consensus and divergence of opinion on the utility and practice of risk assessment. Central to the debate were the issues of whether ERA appropriately incorporates ecological and scientific principle into its conceptual paradigm. Advocates argue that ERA effectively does both, noting that much of the fault detractors find with the process has more to do with its practice than its purpose. Critics argue that failure to validate ERA predictions and the tendency to over-simplify ecological principles compromise the integrity of ERA and may lead to misleading advice on the appropriate responses to environmental problems. All authors felt that many improvements could be made, including validation, better definition of the ecological questions and boundaries of ERA, improved harmonization of selected methods, and improvements in the knowledge base. Despite identified deficiencies, most authors felt that ERA was a useful process undergoing evolutionary changes that will inevitably determine the range of environmental problems to which it can be appropriately applied. The views expressed give ERA a cautious vote of approval and highlight many of the critical strengths and weaknesses in one of our most important environmental assessment tools.KEY WORDS: Ecological risk assessment; Ecology; Probability

Enhanced Recovery after Emergency Surgery: A Systematic Review.

PubMed

Paduraru, Mihai; Ponchietti, Luca; Casas, Isidro Martinez; Svenningsen, Peter; Zago, Mauro

2017-04-01

To evaluate the current scientific evidence for the applicability, safety and effectiveness of pathways of enhanced recovery after emergency surgery (ERAS). We undertook a search using PubMed and Cochrane databases for ERAS protocols in emergency cases. The search generated 65 titles; after eliminating the papers not meeting search criteria, we selected 4 cohort studies and 1 randomized clinical trial (RCT). Data extracted for analysis consisted of: patient age, type of surgery performed, ERAS elements implemented, surgical outcomes in terms of postoperative complications, mortality, length of stay (LOS) and readmission rate. The number of ERAS items applied was good, ranging from 11 to 18 of the 20 recommended by the ERAS Society. The implementation resulted in fewer postoperative complications. LOS for ES patients was shorter when compared to conventional care. Mortality, specifically reported in three studies, was equal or lower with ERAS. Readmission rates varied widely and were generally higher for the intervention group but without statistical significance. The studies reviewed agreed that ERAS in emergency surgery (ES) was feasible and safe with generally better outcomes. Lower compliance with some of the ERAS items shows the need for the protocol to be adapted to ES patients. More evidence is clearly required as to what can improve outcomes and how this can be formulated into an effective care pathway for the heterogeneous ES patient.

Implementation of the Spanish ERAS program in bariatric surgery.

PubMed

Ruiz-Tovar, Jaime; Muñoz, José Luis; Royo, Pablo; Duran, Manuel; Redondo, Elisabeth; Ramirez, Jose Manuel

2018-03-08

The essence of Enhanced Recovery After Surgery (ERAS) programs is the multimodal approach, and many authors have demonstrated safety and feasibility in fast track bariatric surgery. According to this concept, a multidisciplinary ERAS program for bariatric surgery has been developed by the Spanish Fast Track Group (ERAS Spain). The aim of this study was to analyze the initial implementation of this Spanish National ERAS protocol in bariatric surgery, comparing it with a historical cohort receiving standard care. A multi-centric prospective study was performed, including 233 consecutive patients undergoing bariatric surgery during 2015 and following ERAS protocol. It was compared with a historical cohort of 286 patients, who underwent bariatric surgery at the same institutions between 2013 and 2014 and following standard care. Compliance with the protocol, morbidity, mortality, hospital stay and readmission were evaluated. Bariatric techniques performed were Roux-en-Y gastric bypass and sleeve gastrectomy. There were no significant differences in complications, mortality and readmission. Postoperative pain and hospital stay were significantly lower in the ERAS group. The total compliance to protocol was 80%. The Spanish National ERAS protocol is a safe issue, obtaining similar results to standard care in terms of complications, reoperations, mortality and readmissions. It is associated with less postoperative pain and earlier hospital discharge.

Isotropic cosmological models in F(T,TG) theory

NASA Astrophysics Data System (ADS)

Sharif, M.; Nazir, Kanwal

2016-09-01

This paper is devoted to study evolution of the isotropic universe models in the framework of F(T,TG) gravity (T represents torsion scalar and TG is the teleparallel equivalent of the Gauss-Bonnet (GB) term). We construct F(T,TG) models by taking different eras of the universe like non-relativistic and relativistic matter eras, dark energy (DE) dominated era and their combinations. It is found that the reconstructed models indicate decreasing behavior for DE dominated era and its combination with other eras. We also discuss stability of each reconstructed model. Finally, we evaluate equation of state (EoS) parameter by considering two models and study its behavior graphically.

Inflation with a smooth constant-roll to constant-roll era transition

NASA Astrophysics Data System (ADS)

Odintsov, S. D.; Oikonomou, V. K.

2017-07-01

In this paper, we study canonical scalar field models, with a varying second slow-roll parameter, that allow transitions between constant-roll eras. In the models with two constant-roll eras, it is possible to avoid fine-tunings in the initial conditions of the scalar field. We mainly focus on the stability of the resulting solutions, and we also investigate if these solutions are attractors of the cosmological system. We shall calculate the resulting scalar potential and, by using a numerical approach, we examine the stability and attractor properties of the solutions. As we show, the first constant-roll era is dynamically unstable towards linear perturbations, and the cosmological system is driven by the attractor solution to the final constant-roll era. As we demonstrate, it is possible to have a nearly scale-invariant power spectrum of primordial curvature perturbations in some cases; however, this is strongly model dependent and depends on the rate of the final constant-roll era. Finally, we present, in brief, the essential features of a model that allows oscillations between constant-roll eras.

Imported acquired immunodeficiency syndrome-related histoplasmosis in metropolitan France: a comparison of pre-highly active anti-retroviral therapy and highly active anti-retroviral therapy eras.

PubMed

Peigne, Vincent; Dromer, Françoise; Elie, Caroline; Lidove, Olivier; Lortholary, Olivier

2011-11-01

Histoplasma capsulatum var. capsulatum infection is rare outside disease-endemic areas. Clinical presentation and outcome of acquired immunodeficiency syndrome-related histoplasmosis are unknown in non-endemic areas with wide access to highly active anti-retroviral therapy (HAART). Retrospective analysis of cases recorded at the French National Reference Center for Mycoses and Antifungals during two decades: pre-HAART (1985-1994) and HAART (1997-2006). Clinical features and outcome of all adults with proven acquired immunodeficiency syndrome-related histoplasmosis were compared between the two periods. One hundred four patients were included (40 during the pre-HAART era and 64 during the HAART era). Diagnosis was established a mean of 62 days after onset of symptoms. One-year overall mortality rates decreased from 53% (pre-HAART era) to 22% (HAART era). Diagnosis during the pre-HAART era and an older age were the only independent factors associated with death. Histoplasmosis is a rare invasive fungal infection outside disease-endemic areas. Its prognosis improved significantly during the HAART era.

Imported Acquired Immunodeficiency Syndrome–Related Histoplasmosis in Metropolitan France: A Comparison of Pre–Highly Active Anti-Retroviral Therapy and Highly Active Anti-Retroviral Therapy Eras

PubMed Central

Peigne, Vincent; Dromer, Françoise; Elie, Caroline; Lidove, Olivier; Lortholary, Olivier

2011-01-01

Histoplasma capsulatum var. capsulatum infection is rare outside disease-endemic areas. Clinical presentation and outcome of acquired immunodeficiency syndrome–related histoplasmosis are unknown in non-endemic areas with wide access to highly active anti-retroviral therapy (HAART). Retrospective analysis of cases recorded at the French National Reference Center for Mycoses and Antifungals during two decades: pre-HAART (1985–1994) and HAART (1997–2006). Clinical features and outcome of all adults with proven acquired immunodeficiency syndrome–related histoplasmosis were compared between the two periods. One hundred four patients were included (40 during the pre-HAART era and 64 during the HAART era). Diagnosis was established a mean of 62 days after onset of symptoms. One-year overall mortality rates decreased from 53% (pre-HAART era) to 22% (HAART era). Diagnosis during the pre-HAART era and an older age were the only independent factors associated with death. Histoplasmosis is a rare invasive fungal infection outside disease-endemic areas. Its prognosis improved significantly during the HAART era. PMID:22049053

Anomaly Detection in Power Quality at Data Centers

NASA Technical Reports Server (NTRS)

Grichine, Art; Solano, Wanda M.

2015-01-01

The goal during my internship at the National Center for Critical Information Processing and Storage (NCCIPS) is to implement an anomaly detection method through the StruxureWare SCADA Power Monitoring system. The benefit of the anomaly detection mechanism is to provide the capability to detect and anticipate equipment degradation by monitoring power quality prior to equipment failure. First, a study is conducted that examines the existing techniques of power quality management. Based on these findings, and the capabilities of the existing SCADA resources, recommendations are presented for implementing effective anomaly detection. Since voltage, current, and total harmonic distortion demonstrate Gaussian distributions, effective set-points are computed using this model, while maintaining a low false positive count.

Thermo Gravimetric and Differential Thermal Analysis of Clay of Western Rajasthan (india)

NASA Astrophysics Data System (ADS)

Shekhawat, M. S.

The paper presents the study of thermo gravimetric and differential thermal analysis of blended clay. Western part of Rajasthan (India) is rich resource of Ball clays and it is mainly used by porcelain, sanitary ware, and tile industry. The quality and grade of clay available in the region vary from one deposit to other. To upgrade the fired colour and strength properties, different variety of clays may be blended together. The paper compares the results of thermal analysis one of blended clay B2 with reference clay of Ukraine which is imported by industries owners. The result revealed that the blended clay is having mineral kaolinite while the Ukrainian clay is Halloysite.

Sierra Toolkit Manual Version 4.48.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sierra Toolkit Team

This report provides documentation for the SIERRA Toolkit (STK) modules. STK modules are intended to provide infrastructure that assists the development of computational engineering soft- ware such as finite-element analysis applications. STK includes modules for unstructured-mesh data structures, reading/writing mesh files, geometric proximity search, and various utilities. This document contains a chapter for each module, and each chapter contains overview descriptions and usage examples. Usage examples are primarily code listings which are generated from working test programs that are included in the STK code-base. A goal of this approach is to ensure that the usage examples will not fall outmore » of date. This page intentionally left blank.« less

A Feasibility Study of Incorporating ARPANET Type Technology at United States Naval Installations

DTIC Science & Technology

1980-03-01

8217^ of t’^e r-^n ^’^?as of ’’esearcn effort for HAPpA is in 1-hp fie1o of roTi-nAoi, Control and CoTrrunications (C3) or Cee-cu’^ed. ithin this fiel-^ is...the Adv/^pced Con^nand ana Control ^rrnyfaQt^Jr^’^ ’’’esthe^-’/ freouently calleo aCCAJ, One function o* ACCAT is to exolore areas of coTimana and... control in the "nited Stat-^-x; "-iavy. The cvjroose c^ tnp ACCAT effort is to -’eve^’^o r p. val!j>»:e ?nH tes*" hard ’ware and software technolooy

Application of liquid chromatography-electrospray ionization mass spectrometry for study of steroid-converting enzymes.

PubMed

Miksík, Ivan; Mikulíková, Katerina; Pácha, Jirí; Kucka, Marek; Deyl, Zdenek

2004-02-05

A high-performance liquid chromatography-atmospheric pressure ionization-electrospray ionization mass spectrometry (HPLC-API-ESI-MS) method was developed for the analysis of steroids in a study of steroid-converting enzymes. Separations ware done on a Zorbax Eclipse XDB-C18 column (eluted with a linear methanol-water-acetic acid gradient) and identification of the steroids involved was done by API-ESI-MS using positive ion mode and extracted ion analysis. The applicability of the present method for studying steroid metabolism was proven in assaying two steroid-converting enzymes (20beta-hydroxysteroid dehydrogenase and 11beta-hydroxysteroid dehydrogenase) in various biological samples (rat and chicken intestine, chicken oviduct).

Strategic Integration of Open Educational Resources in Higher Education

NASA Astrophysics Data System (ADS)

Schaffert, Sandra

Open Educational Resources (OERs) can be seen as social movement but are also implemented as strategic measures in higher education institutions (HEIs). This chapter describes the current aims and experiences of OERs in HEIs. Starting with definitions and milestones in respect of the current status, this chapter gives an overview of projects and implementation objectives and it describes two concrete case studies, i.e., the Massachusetts Institute of Technology Open CourseWare project and the OpenLearn project at the Open University in the United Kingdom. The aim of this chapter is to give a comprehensive overview to decision makers and policy drivers within higher education organizations, and thus it develops a blueprint of an implementation model.

Simulating Terrestrial Gamma-ray Flashes using SWORD (Invited)

NASA Astrophysics Data System (ADS)

Gwon, C.; Grove, J.; Dwyer, J. R.; Mattson, K.; Polaski, D.; Jackson, L.

2013-12-01

We report on simulations of the relativistic feedback discharges involved with the production of terrestrial gamma-ray flashes (TGFs). The simulations were conducted using Geant4 using the SoftWare for the Optimization of Radiation Detectors (SWORD) framework. SWORD provides a graphical interface for setting up simulations in select high-energy radiation transport engines. Using Geant4, we determine avalanche length, the energy spectrum of the electrons and gamma-rays as they leave the field region, and the feedback factor describing the degree to which the production of energetic particles is self-sustaining. We validate our simulations against previous work in order to determine the reliability of our results. This work is funded by the Office of Naval Research.

Radioactivity of Consumer Products

NASA Astrophysics Data System (ADS)

Peterson, David; Jokisch, Derek; Fulmer, Philip

2006-11-01

A variety of consumer products and household items contain varying amounts of radioactivity. Examples of these items include: FiestaWare and similar glazed china, salt substitute, bananas, brazil nuts, lantern mantles, smoke detectors and depression glass. Many of these items contain natural sources of radioactivity such as Uranium, Thorium, Radium and Potassium. A few contain man-made sources like Americium. This presentation will detail the sources and relative radioactivity of these items (including demonstrations). Further, measurements of the isotopic ratios of Uranium-235 and Uranium-238 in several pieces of china will be compared to historical uses of natural and depleted Uranium. Finally, the presenters will discuss radiation safety as it pertains to the use of these items.

Remote Acoustic Emission Monitoring of Metal Ware and Welded Joints

NASA Astrophysics Data System (ADS)

Kapranov, Boris I.; Sutorikhin, Vladimir A.

2017-10-01

An unusual phenomenon was revealed in the metal-ultrasound interaction. Microwave sensor generates surface electric conductivity oscillations from exposure to elastic ultrasonic vibrations on regions of defects embracing micro-defects termed as “crack mouth.” They are known as the region of “acoustic activity,” method of Acoustic Emission (AE) method. It was established that the high phase-modulation coefficient of reflected field generates intentional Doppler radar signal with the following parameters: amplitude-1-5 nm, 6-30 dB adjusted to 70- 180 mm. This phenomenon is termed as “Gorbunov effect,” which is applied as a remote non-destructive testing method replacing ultrasonic flaw detection and acoustic emission methods.

Development of a structured observational method for the systematic assessment of school food-choice architecture.

PubMed

Ozturk, Orgul D; McInnes, Melayne M; Blake, Christine E; Frongillo, Edward A; Jones, Sonya J

2016-01-01

The objective of this study is to develop a structured observational method for the systematic assessment of the food-choice architecture that can be used to identify key points for behavioral economic intervention intended to improve the health quality of children's diets. We use an ethnographic approach with observations at twelve elementary schools to construct our survey instrument. Elements of the structured observational method include decision environment, salience, accessibility/convenience, defaults/verbal prompts, number of choices, serving ware/method/packaging, and social/physical eating environment. Our survey reveals important "nudgeable" components of the elementary school food-choice architecture, including precommitment and default options on the lunch line.

Herbological studies of Coptidis rhizoma (Part 2): on the old Japanese name of Coptis japonica makino.

PubMed

Kawamoto, M; Mikage, M

1999-01-01

The rhizome of Coptis plant of the family ranunculaceae has been used in traditional Chinese medicine as a crude drug (Huanglian in present Chinese). In Japan, the rhizome of Coptis japonica Makino (the botanical name of which is "Ohren" in modern Japanese) has been utilized as a crude drug since the Nara era. The Japanese name in those days was "Kakumakusa based on descriptions in old books written in the Heian era. It changed to "Kakumikusa" early in the Edo era, and then changed again to Kakumakusa later in the Edo era. Through this herbological study, it was conjectured as follows: The resemblance between Chinese characters (or MA) and (or MI) in cursive style caused mis-copying of the character. After the "Honzo-wamyo, written in the Heian era, was revised in the late Edo era, and on which the name was accurately written as Kakumakusa, the mistake was corrected.

The influence of HLA mismatches and immunosuppression on kidney graft survival: an analysis of more than 1300 patients.

PubMed

Martins, L; Fonseca, I; Sousa, S; Matos, C; Santos, J; Dias, L; Henriques, A C; Sarmento, A M; Cabrita, A

2007-10-01

New immunosuppressive drugs used in kidney transplantation decreased the incidence of acute rejection. It was hypothesized that, with their power, the importance of HLA matching was decreased. To evaluate the influence of HLA matching, immunosuppression, and other possible risk factors, we analyzed data of 1314 consecutive deceased donor kidney transplantation. We divided the patient population into 4 cohorts, according to the era of transplantation: era 1, before 1990, azathioprine (Aza) and cyclosporine (Csa) no microemulsion; era 2, between 1990 and 1995, Csa microemulsion; era 3, between 1996 and 2000, wide use of mycophenolate mofetil (MMF) and anti-thymocyte globulin (ATG); and era 4, after 2000, marked by sirolimus and tacrolimus (TAC) use. Multivariate analysis compared death-censored graft survival. Using as reference the results obtained with 0 HLA mismatches, we verified, during era 1 and era 2, an increased risk of graft loss for all of the subgroups with HLA mismatch >0. However, during era 3 and era 4, the number of HLA mismatches did not influence graft survival. Although acute rejection and delayed graft function, which decreased in the later periods, remained as prognostic factors for graft loss. Considering the immunosuppressive protocol with Csa+Aza+Pred as reference, protocols used after 1995 with Pred+Csa+ATG, with Pred+Csa+MMF, and with Pred+Tac+MMF presented better survival results. Results showed that the significance of HLA matching decreased while the results improved with the new immunosuppressant drugs. These observations support the hypothesis that the weakened importance of HLA matching may be a consequence of the increasing efficacy of the immunosuppression.

Application of enhanced recovery after gastric cancer surgery: An updated meta-analysis

PubMed Central

Wang, Liu-Hua; Zhu, Ren-Fei; Gao, Cheng; Wang, Shou-Lin; Shen, Li-Zong

2018-01-01

AIM To provide an updated assessment of the safety and efficacy of enhanced recovery after surgery (ERAS) protocols in elective gastric cancer (GC) surgery. METHODS PubMed, Medline, EMBASE, World Health Organization International Trial Register, and Cochrane Library were searched up to June 2017 for all available randomized controlled trials (RCTs) comparing ERAS protocols and standard care (SC) in GC surgery. Thirteen RCTs, with a total of 1092 participants, were analyzed in this study, of whom 545 underwent ERAS protocols and 547 received SC treatment. RESULTS No significant difference was observed between ERAS and control groups regarding total complications (P = 0.88), mortality (P = 0.50) and reoperation (P = 0.49). The incidence of pulmonary infection was significantly reduced (P = 0.03) following gastrectomy. However, the readmission rate after GC surgery nearly tripled under ERAS (P = 0.009). ERAS protocols significantly decreased the length of postoperative hospital stay (P < 0.00001) and medical costs (P < 0.00001), and accelerated bowel function recovery, as measured by earlier time to the first flatus (P = 0.0004) and the first defecation (P < 0.0001). Moreover, ERAS protocols were associated with a lower level of serum inflammatory response, higher serum albumin, and superior short-term quality of life (QOL). CONCLUSION Collectively, ERAS results in accelerated convalescence, reduction of surgical stress and medical costs, improved nutritional status, and better QOL for GC patients. However, high-quality multicenter RCTs with large samples and long-term follow-up are needed to more precisely evaluate ERAS in radical gastrectomy. PMID:29662294

Retrospective case-control non-inferiority analysis of intravenous lidocaine in a colorectal surgery enhanced recovery program.

PubMed

Naik, Bhiken I; Tsang, Siny; Knisely, Anne; Yerra, Sandeep; Durieux, Marcel E

2017-01-31

Enhanced recovery after surgery (ERAS) programs typically utilizes multi-modal analgesia to reduce perioperative opioid consumption. Systemic lidocaine is used in several of these ERAS algorithms and has been shown to reduce opioid use after colorectal surgery. However it is unclear how much the other components of an ERAS protocol contribute to the final outcome. Using a noninferiority analysis we sought to assess the role of perioperative lidocaine in an ERAS program for colorectal surgery, using pain and opioid consumption as outcomes. We conducted a retrospective review of patients who had received intravenous lidocaine perioperatively during colorectal surgery. We matched them with patients who were managed using a multi-component ERAS protocol, which included perioperative lidocaine. We tested a joint hypothesis of noninferiority of lidocaine infusion to ERAS protocol in postoperative pain scores and opioid consumption. We assigned a noninferiority margin of 1 point (on an 11-point numerical rating scale) difference in pain and a ratio [mean (lidocaine) / mean (ERAS)] of 1.2 in opioid consumption, respectively. Fifty-two patients in the lidocaine group were matched with patients in the ERAS group. With regards to opioid consumption, in the overall [1.68 (1.43-1.98)] [odds ratio (95% confidence interval)] analysis and on postoperative day (POD) 1 [2.38 (1.74-3.31)] lidocaine alone was inferior to multi-modal analgesia. On POD 2 and beyond, although the mean odds ratio for opioid consumption was 1.43 [1.43 (1.17-1.73)], the lower limit extended beyond the pre-defined cut-off of 1.2, rendering the outcome inconclusive. For pain scores lidocaine is non-inferior to ERAS [-0.17 (-1.08-0.74)] on POD 2 and beyond. Pain scores on POD 1 and in the overall cohort were inconclusive based on the noninferiority analysis. The addition of a multi-component ERAS protocol to intravenous lidocaine incrementally reduces opioid consumption, most evident on POD 1. For pain scores the data is inconclusive on POD 1, however on POD 2 and beyond lidocaine alone is non-inferior to an ERAS program with lidocaine. Opioid-related complications, including return of bowel function, were not different between the groups despite reduced opioid use in the ERAS group.

Enhanced recovery after surgery in children: Promising, evidence-based multidisciplinary care.

PubMed

Rove, Kyle O; Edney, John C; Brockel, Megan A

2018-06-01

Enhanced recovery after surgery (ERAS) is a multimodal approach to the care of the surgical patient focused on reducing the stress response and associated physiologic changes that accompany surgery. Over the past 20 years, ERAS programs have been found to result in reduced LOS and complications in adult patients. Despite abundant adult literature describing implementation and outcomes of enhanced recovery programs, pediatric data in this area is sparse. This educational review describes the history and elements of ERAS protocols, reviews the available evidence in adult and pediatric populations, compares and contrasts ERAS with the PSH, and offers strategies for implementation and ideas for future directions of ERAS in children. © 2018 John Wiley & Sons Ltd.

The potential for a new era of supersonic and hypersonic aviation

NASA Technical Reports Server (NTRS)

Harris, Roy V.

1990-01-01

A new era of supersonic and hypersonic aviation is envisioned. The potential for supersonic and hypersonic flight vehicles in this new era is analyzed. Technology challenges that must be met in order to bring in this new era of flight are discussed. The current technical status and future potential are cited in the areas of aerodynamics, propulsion, and structural materials. A next major step in the development of high-speed air transportation is suggested.

Enhanced Recovery after Emergency Surgery: A Systematic Review

PubMed Central

Paduraru, Mihai; Ponchietti, Luca; Casas, Isidro Martinez; Svenningsen, Peter; Zago, Mauro

2017-01-01

Objective: To evaluate the current scientific evidence for the applicability, safety and effectiveness of pathways of enhanced recovery after emergency surgery (ERAS). Methods: We undertook a search using PubMed and Cochrane databases for ERAS protocols in emergency cases. The search generated 65 titles; after eliminating the papers not meeting search criteria, we selected 4 cohort studies and 1 randomized clinical trial (RCT). Data extracted for analysis consisted of: patient age, type of surgery performed, ERAS elements implemented, surgical outcomes in terms of postoperative complications, mortality, length of stay (LOS) and readmission rate. Results: The number of ERAS items applied was good, ranging from 11 to 18 of the 20 recommended by the ERAS Society. The implementation resulted in fewer postoperative complications. LOS for ES patients was shorter when compared to conventional care. Mortality, specifically reported in three studies, was equal or lower with ERAS. Readmission rates varied widely and were generally higher for the intervention group but without statistical significance. Conclusions: The studies reviewed agreed that ERAS in emergency surgery (ES) was feasible and safe with generally better outcomes. Lower compliance with some of the ERAS items shows the need for the protocol to be adapted to ES patients. More evidence is clearly required as to what can improve outcomes and how this can be formulated into an effective care pathway for the heterogeneous ES patient. PMID:28507993

Trends in Wait-list Mortality in Children Listed for Heart Transplantation in the United States

PubMed Central

Singh, Tajinder P.; Almond, Christopher S.; Piercey, Gary; Gauvreau, Kimberlee

2014-01-01

We sought to evaluate trends in overall and race-specific pediatric heart transplant (HT) wait-list mortality in the United States (US) during the last 20 years. We identified all children <18 years old listed for primary HT in the US during 1989–2009 (N=8096, 62% white, 19% black, 13% Hispanic, 6% other) using the Organ Procurement and Transplant Network database. Wait-list mortality was assessed in 4 successive eras (1989–1994, 1995–1999, 2000–2004, and 2005–2009). Overall wait-list mortality declined in successive eras (26%, 23%, 18% and 13%, respectively). The decline across eras remained significant in adjusted analysis (hazard ratio [HR] 0.70 in successive eras, 95% confidence interval [CI] 0.67, 0.74) and was 67% lower for children listed during 2005–2009 vs. those listed during 1989–1994 (HR 0.33, CI 0.28, 0.39). In models stratified by race, wait-list mortality decreased in all racial groups in successive eras. In models stratified by era, minority children were not at higher risk of wait-list mortality in the most recent era. We conclude that the risk of wait-list mortality among US children listed for HT has decreased by two-thirds during the last 20 years. Racial gaps in wait-list mortality present variably in the past are not present in the current era. PMID:21883920

Classroom Activities for the Progressive Era and the World War I Draft.

ERIC Educational Resources Information Center

Mills, Randy

1986-01-01

Provides discussion questions, activities, and projects to be used with EJ515083, "The Progressive Era and the World War I Draft." Includes three political cartoons and two World War I-era songs of opposing viewpoints. (JDH)

Modified enhanced recovery after surgery (ERAS) protocols for patients with obstructive colorectal cancer.

PubMed

Shida, Dai; Tagawa, Kyoko; Inada, Kentaro; Nasu, Keiichi; Seyama, Yasuji; Maeshiro, Tsuyoshi; Miyamoto, Sachio; Inoue, Satoru; Umekita, Nobutaka

2017-02-16

Enhanced recovery after surgery (ERAS) protocols are now well-known to be useful for elective colorectal surgery, as they result in shorter hospital stays without adversely affecting morbidity. However, the efficacy and safety of ERAS protocols for patients with obstructive colorectal cancer have yet to be clarified. We evaluated 122 consecutive resections for obstructive colorectal cancer performed between July 2008 and November 2012 at Tokyo Metropolitan Bokutoh Hospital. Patients with rupture or impending rupture and those who received simple colostomy were excluded. The first set of 42 patients was treated based on traditional protocols, and the latter 80 according to modified ERAS protocols. The main endpoints were length of postoperative hospital stay, postoperative short-term morbidity, rate of readmission within 30 days, and mortality. Differences in modified ERAS protocols relative to traditional care include intensive preoperative counseling (by both surgeons and anesthesiologists), perioperative fluid management (avoidance of sodium/fluid overload), shortening of postoperative fasting period and early provision of oral nutrition, intraoperative warm air body heating, enforced postoperative mobilization, stimulation of gut motility, early removal of urinary catheter, and a multidisciplinary team approach to care. Median (interquartile range) postoperative hospital stay was 10 (10-14.25) days in the traditional group, and seven (7-8.75) days in the ERAS group, showing a 3-day reduction in hospital stay (p < 0.01). According to the Clavien-Dindo classification, overall incidences of grade 2 or higher postoperative complications for the traditional and ERAS groups were 15 and 10% (p = 0.48), and 30-day readmission rates were 0 and 1.3% (p = 1.00), respectively. As for mortality, one patient in the traditional group died and none in the ERAS group (p = 0.34). Modified ERAS protocols for obstructive colorectal cancer reduced hospital stay without adversely affecting morbidity, indicating that ERAS protocols are feasible for patients with obstructive colorectal cancer.

Reduction in liver transplant wait-listing in the era of direct-acting antiviral therapy.

PubMed

Flemming, Jennifer A; Kim, W Ray; Brosgart, Carol L; Terrault, Norah A

2017-03-01

Direct-acting antiviral (DAA) therapy, recently approved for patients with decompensated cirrhosis (DC) secondary to hepatitis C virus (HCV), is associated with improved hepatic function. We analyzed trends in liver transplant (LT) wait-listing (WL) to explore potential impact of effective medical therapy on WL registration. This is a cohort study using the Scientific Registry of Transplant Recipients database from 2003 to 2015. A total of 47,591 adults wait-listed for LT from HCV, hepatitis B virus (HBV), and nonalcoholic steatohepatitis (NASH) were identified. LT indication was defined as DC if the Model for End-Stage Liver Disease (MELD) at WL was ≥15 or hepatocellular carcinoma (HCC). Era of listing was divided into interferon (IFN; 2003-2010), protease inhibitor (PI; 2011-2013), and direct-acting antiviral (DAA; 2014-2015). Annual standardized incidence rates of WL were analyzed using Poisson regression. Adjusted incidences of LT WL for DC in HCV patients decreased by 5% in the PI era (P = 0.004) and 32% in the DAA era (P < 0.001) compared to the IFN era. Listing for DC in HBV also decreased in the PI (-17%; P = 0.002) and DAA eras (-24%; P < 0.001). Conversely, WL for DC in NASH increased by 41% in the PI era (P < 0.001) and 81% in the DAA era (P < 0.001). WL for HCC in both the HCV and NASH populations increased in both the PI and DAA eras (P < 0.001 for all) whereas HCC WL in HBV remained stable (P > 0.05 for all). The rate of LT WL for HCV complicated by DC has decreased by over 30% in the era of DAA therapy. Further reductions in WL are anticipated with increased testing, linkage to care, and access to DAA therapy. (Hepatology 2017;65:804-812). © 2016 by the American Association for the Study of Liver Diseases.

Narcotics reduction, quality and safety in gynecologic oncology surgery in the first year of enhanced recovery after surgery protocol implementation.

PubMed

Bergstrom, Jennifer E; Scott, Marla E; Alimi, Yewande; Yen, Ting-Tai; Hobson, Deborah; Machado, Karime K; Tanner, Edward J; Fader, Amanda N; Temkin, Sarah M; Wethington, Stephanie; Levinson, Kimberly; Sokolinsky, Sam; Lau, Brandyn; Stone, Rebecca L

2018-06-01

Enhanced Recovery After Surgery (ERAS) programs are mechanisms for achieving value-based improvements in surgery. This report provides a detailed analysis of the impact of an ERAS program on patient outcomes as well as quality and safety measures during implementation on a gynecologic oncology service at a major academic medical center. A retrospective review of gynecologic oncology patients undergoing elective laparotomy during the implementation phase of an ERAS program (January 2016 through December 2016) was performed. Patient demographics, surgical variables, postoperative outcomes, and adherence to core safety measures, including antimicrobial and venous thromboembolism (VTE) prophylaxis, were compared to a historical patient cohort (January 2015 through December 2015). Statistical analyses were performed using t-tests, Wilcoxon rank sum tests, and Chi squared tests. The inaugural 109 ERAS program participants were compared to a historical patient cohort (n=158). There was no difference in BMI, race, malignancy, or complexity of procedure between cohorts. ERAS patients required less narcotics (70.7 vs 127.4, p=0.007, oral morphine equivalents) and PCA use (32.1% vs. 50.6%, p=0.002). Despite this substantial reduction in narcotics, ERAS patients did not report more pain and in fact reported significantly less pain by postoperative day 3. There were no differences in length of stay (5days), complication rates (13.8% vs. 20.3%, p=0.17) or 30-day readmission rates (9.5 vs 11.9%, p=0.54) between ERAS and historical patients, respectively. Compliance with antimicrobial prophylaxis was 97.2%. However, 33.9% of ERAS patients received substandard preoperative VTE prophylaxis. ERAS program implementation resulted in reductions in narcotic requirements and PCA use without changes in length of stay or readmission rates. Compliance should be diligently audited during the implementation phase of ERAS programs, with special attention to adherence to pre-existing core safety measures. Copyright © 2018 Elsevier Inc. All rights reserved.

Toward Current Standards of Donor Right Hepatectomy for Adult-to-Adult Live Donor Liver Transplantation Through the Experience of 200 Cases

PubMed Central

Chan, See Ching; Fan, Sheung Tat; Lo, Chung Mau; Liu, Chi Leung; Wong, John

2007-01-01

Objective: To define the current standards of donor right hepatectomy, including the middle hepatic vein for adult-to-adult live donor liver transplantation. Summary Background Data: Donor morbidity and mortality are inevitable given the ultra-major nature of the donor operation. Results from a matured center could define the true impact of this donor procedure most accurately. Patients and Methods: From May 9, 1996 to April 13, 2005, 200 consecutive donors underwent donor right hepatectomy at the University of Hong Kong Medical Center. All right liver grafts except one included the middle hepatic vein. Donor characteristics, operation time, blood loss, hospital stay, laboratory results, and complications graded by Clavien's classification divided into four eras (each consecutive 50 cases) were compared. Results: Donor characteristics of the four eras were generally comparable. Operative outcomes improved progressively through the four eras. From era 1 to era 4, operation time decreased from 598 minutes (range, 378–932 minutes) to 391 minutes (range, 304–635 minutes). Blood loss also decreased from 500 mL (200–1600 mL) of era 1 to 251 mL (range, 95–595 mL) of era 4. Overall complication rate was 20.5% (41 of 200). Complications rates from eras 1 to 4 were 34%, 16%, 16%, and 16%, respectively. The most common complications were of grade I (24 of 41, 58.5%). A late donor death occurred in era 4 from the development of a duodenocaval fistula 10 weeks postoperation, giving a donor mortality of 0.5% (1 of 200). Conclusions: This study validated the estimated morbidity and mortality of donor right hepatectomy of 20% and 0.5%, respectively. The data provide reference for counseling potential donors and setting the standards of donor right hepatectomy in the current era. PMID:17197973

[Effects of chlorides on Cd transformation in a simulated grate incinerator during sludge incineration process ].

PubMed

Liu, Jing-yong; Zhuo, Zhong-xu; Sun, Shui-yu; Luo, Guang-qian; Li, Xiao-ming; Xie, Wu-ming; Wang, Yu- jie; Yang, Zuo-yi; Zhao, Su-ying

2014-09-01

The effects of organic chloride-PVC and inorganic chloride-NaCl on Cd partitioning during sludge incineration with adding Cd(CH3COO)2 . 2H2O to the real sludge were investigated using a simulated tubular incineration furnace. And transformation and distribution of Cd were studied in different sludge incineration operation conditions. The results indicated that the partitioning of Cd tended to be enhanced in the fly ash and fule gas as the chloride content increasing. The migration and transformation of Cd-added sludge affected by different chloride were not obvious with the increasing of chloride content. With increasing temperature, organic chloride (PVC) and inorganic chloride (NaC1) can reduce the Cd distribution in the bottom ash. However, the effect of chlorides, the initial concentration and incineration time on Cd emissions had no significant differences. Using SEM-EDS and XRD technique, different Cd compounds including CdCl2, Na2CdCl4, K2CdCl6, K2CdSiO4 and NaCdO2 were formed in the bottom ash and fly ash after adding NaCl to the sludge. In contrast, after adding PVC to the sludge, the Na2CdCl4 and CdCl2 were the main forms of Cd compounds, at the same time, K4CdCI6 and K6CdO4 were also formed. The two different mechanisms of chlorides effects on Cd partitioning were affected by the products of Cd compound types and forms.

Prophylactic effect of four prescriptions of traditional Chinese medicine on alpha-naphthylisothiocyanate and carbon tetrachloride induced toxicity in rats.

PubMed

Lin, K J; Chen, J C; Tsauer, W; Lin, C C; Lin, J G; Tsai, C C

2001-12-01

To study the prophylactic effects of four Chinese traditional prescriptions against experimental liver injury. Liver toxins, alpha-naphthylisothiocyanate (ANIT), and carbon tetrachloride (CCl4) were used to induce acute liver injury. Simo Yin(SMY), Guizhi Fuling Wan (GFW), Xieqing Wan (XQW), and Sini San (SNS) were fed (500 mg/kg, in saline, po) to the rats before toxin administration. All the animals were killed 48 h after toxin insulted. Serum index of liver function and hepatic lipid peroxidation (LPO) were estimated. Histopathological observation was conducted simultaneously. The rats treated with ANIT exhibited elevations of serum total bilirubin (TBI), alkaline phosphatase (ALP), glutamate-oxalate- transaminase (GOT), glutamate-pyruvate-transaminase (GPT), as well as cholestasis and parenchyma necrosis. In rats, challenged with ANIT, receiving the pre-treatment of prescriptions of SMY, XQW, and SNS, the biochemical and morphological parameters of liver injury were significantly reduced. The increased LPO level in liver tissue, associated with the provoked serum GOT and GPT levels were the salient features observed in CCl4-insulting rats. Pre-treatment of four prescriptions showed a remarkable protective effect, and also was effective in counteracting the free radical toxicity by bringing about a significant decrease in peroxidative level. These recipes ameliorate liver damage induced by both ANIT and CCl4 despite the differences in their mechanisms of injury. Therefore they may be able to exert hepatoprotective effects through more than one mechanism of action because they contained a mixture of anti-hepatotoxic ingredients with mutual reinforcement and assistance.

Use hyperspectral remote sensing technique to monitoring pine wood nomatode disease preliminary

NASA Astrophysics Data System (ADS)

Qin, Lin; Wang, Xianghong; Jiang, Jing; Yang, Xianchang; Ke, Daiyan; Li, Hongqun; Wang, Dingyi

2016-10-01

The pine wilt disease is a devastating disease of pine trees. In China, the first discoveries of the pine wilt disease on 1982 at Dr. Sun Yat-sen's Mausoleum in Nanjing. It occurred an area of 77000 hm2 in 2005, More than 1540000 pine trees deaths in the year. Many districts of Chongqing in Three Gorges Reservoir have different degrees of pine wilt disease occurrence. It is a serious threat to the ecological environment of the reservoir area. Use unmanned airship to carry high spectrum remote sensing monitoring technology to develop the study on pine wood nematode disease early diagnosis and early warning and forecasting in this study. The hyper spectral data and the digital orthophoto map data of Fuling District Yongsheng Forestry had been achieved In September 2015. Using digital image processing technology to deal with the digital orthophoto map, the number of disease tree and its distribution is automatic identified. Hyper spectral remote sensing data is processed by the spectrum comparison algorithm, and the number and distribution of disease pine trees are also obtained. Two results are compared, the distribution area of disease pine trees are basically the same, indicating that using low air remote sensing technology to monitor the pine wood nematode distribution is successful. From the results we can see that the hyper spectral data analysis results more accurate and less affected by environmental factors than digital orthophoto map analysis results, and more environment variable can be extracted, so the hyper spectral data study is future development direction.

Analysis of Marine Corps Renewable Energy Planning to Meet Installation Energy Security Requirements

DTIC Science & Technology

2013-12-03

experimentation eventually gives way to the era of ferment . A few new technologies break through in the industry and are applied to a growing number of niche...experimentation and ferment eventually give way to an era of incremental change, where the industry down-selects to the most successful and efficient...clearly in the later part of the era of incremental change. Most renewables, however, are only just now moving into the second phase, the era of ferment

Elevated levels of Era GTPase improve growth, 16S rRNA processing, and 70S ribosome assembly of Escherichia coli lacking highly conserved multifunctional YbeY endoribonuclease.

PubMed

Ghosal, Anubrata; Babu, Vignesh M P; Walker, Graham C

2018-06-18

YbeY is a highly conserved, multifunctional endoribonuclease that plays a significant role in ribosome biogenesis and has several additional roles. Here, we show in Escherichia coli that overexpressing the conserved GTPase, Era, partially suppresses the growth defect of a ΔybeY strain while improving 16S rRNA processing and 70S ribosome assembly. This suppression requires both Era's ability to hydrolyze GTP and the function of three exoribonucleases, RNase II, RNase R and RNase PH, suggesting a model for Era's action. Overexpressing Vibrio cholerae Era similarly partially suppresses the defects of an E. coli ΔybeY strain indicating this property of Era is conserved in bacteria other than E. coli Importance This work provides additional insights into the critical, but still incompletely understood, mechanism of the processing of the E. coli 16S rRNA 3'-terminus. The highly conserved GTPase, Era, is known to bind to the precursor of the 16S rRNA near its 3-end. Both the endoribonuclease YbeY, which binds to Era, and four exoribonucleases have been implicated in this 3'-end processing. Results reported here offer additional insights into the role of Era in 16S rRNA 3'-maturation and into the relationship between the action of the endoribonuclease YbeY and the four exoribonucleases. This study also hints at why YbeY is only essential in some bacteria and suggests that the YbeY could be a target for a new class of antibiotic in these bacteria. Copyright © 2018 American Society for Microbiology.

Towards a landscape scale management of pesticides: ERA using changes in modelled occupancy and abundance to assess long-term population impacts of pesticides.

PubMed

Topping, Chris J; Craig, Peter S; de Jong, Frank; Klein, Michael; Laskowski, Ryszard; Manachini, Barbara; Pieper, Silvia; Smith, Rob; Sousa, José Paulo; Streissl, Franz; Swarowsky, Klaus; Tiktak, Aaldrik; van der Linden, Ton

2015-12-15

Pesticides are regulated in Europe and this process includes an environmental risk assessment (ERA) for non-target arthropods (NTA). Traditionally a non-spatial or field trial assessment is used. In this study we exemplify the introduction of a spatial context to the ERA as well as suggest a way in which the results of complex models, necessary for proper inclusion of spatial aspects in the ERA, can be presented and evaluated easily using abundance and occupancy ratios (AOR). We used an agent-based simulation system and an existing model for a widespread carabid beetle (Bembidion lampros), to evaluate the impact of a fictitious highly-toxic pesticide on population density and the distribution of beetles in time and space. Landscape structure and field margin management were evaluated by comparing scenario-based ERAs for the beetle. Source-sink dynamics led to an off-crop impact even when no pesticide was present off-crop. In addition, the impacts increased with multi-year application of the pesticide whereas current ERA considers only maximally one year. These results further indicated a complex interaction between landscape structure and pesticide effect in time, both in-crop and off-crop, indicating the need for NTA ERA to be conducted at landscape- and multi-season temporal-scales. Use of AOR indices to compare ERA outputs facilitated easy comparison of scenarios, allowing simultaneous evaluation of impacts and planning of mitigation measures. The landscape and population ERA approach also demonstrates that there is a potential to change from regulation of a pesticide in isolation, towards the consideration of pesticide management at landscape scales and provision of biodiversity benefits via inclusion and testing of mitigation measures in authorisation procedures. Copyright © 2015 Elsevier B.V. All rights reserved.

Enhanced Recovery After Surgery: A Review.

PubMed

Ljungqvist, Olle; Scott, Michael; Fearon, Kenneth C

2017-03-01

Enhanced Recovery After Surgery (ERAS) is a paradigm shift in perioperative care, resulting in substantial improvements in clinical outcomes and cost savings. Enhanced Recovery After Surgery is a multimodal, multidisciplinary approach to the care of the surgical patient. Enhanced Recovery After Surgery process implementation involves a team consisting of surgeons, anesthetists, an ERAS coordinator (often a nurse or a physician assistant), and staff from units that care for the surgical patient. The care protocol is based on published evidence. The ERAS Society, an international nonprofit professional society that promotes, develops, and implements ERAS programs, publishes updated guidelines for many operations, such as evidence-based modern care changes from overnight fasting to carbohydrate drinks 2 hours before surgery, minimally invasive approaches instead of large incisions, management of fluids to seek balance rather than large volumes of intravenous fluids, avoidance of or early removal of drains and tubes, early mobilization, and serving of drinks and food the day of the operation. Enhanced Recovery After Surgery protocols have resulted in shorter length of hospital stay by 30% to 50% and similar reductions in complications, while readmissions and costs are reduced. The elements of the protocol reduce the stress of the operation to retain anabolic homeostasis. The ERAS Society conducts structured implementation programs that are currently in use in more than 20 countries. Local ERAS teams from hospitals are trained to implement ERAS processes. Audit of process compliance and patient outcomes are important features. Enhanced Recovery After Surgery started mainly with colorectal surgery but has been shown to improve outcomes in almost all major surgical specialties. Enhanced Recovery After Surgery is an evidence-based care improvement process for surgical patients. Implementation of ERAS programs results in major improvements in clinical outcomes and cost, making ERAS an important example of value-based care applied to surgery.

Implementation Costs of an Enhanced Recovery After Surgery Program in the United States: A Financial Model and Sensitivity Analysis Based on Experiences at a Quaternary Academic Medical Center.

PubMed

Stone, Alexander B; Grant, Michael C; Pio Roda, Claro; Hobson, Deborah; Pawlik, Timothy; Wu, Christopher L; Wick, Elizabeth C

2016-03-01

Despite positive results from several international Enhanced Recovery After Surgery (ERAS) protocols, the United States has been slow to adopt ERAS protocols, in part due to concern regarding the expenses of such a program. We sought to evaluate the potential annual net cost savings of implementing a US-based ERAS program. Using data from existing publications and experience with an ERAS program, a model of net financial costs was developed for surgical groups of escalating numbers of annual cases. Our example scenario provided a financial analysis of the implementation of an ERAS program at a United States academic institution based on data from the ERAS Program for Colorectal Surgery at The Johns Hopkins Hospital. Based on available data from the United States, ERAS programs lead to reductions in lengths of hospital stay that range from 0.7 to 2.7 days and substantial direct cost savings. Using example data from a quaternary hospital, the considerable cost of $552,783 associated with implementation of an ERAS program was offset by even greater savings in the first year of nearly $948,500, yielding a net savings of $395,717. Sensitivity analysis across several caseload and direct cost scenarios yielded similar savings in 20 of the 27 projections. Enhanced Recovery After Surgery protocols have repeatedly led to reduction in length of hospital stay and improved surgical outcomes. A financial model, based on published data and experience, projects that investment in an ERAS program can also lead to net financial savings for US hospitals. Copyright © 2016 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

Fever as an Initial Manifestation of Enthesitis-Related Arthritis Subtype of Juvenile Idiopathic Arthritis: Retrospective Study

PubMed Central

Guo, Ruru; Cao, Lanfang; Kong, Xianming; Liu, Xuesong; Xue, Haiyan; Shen, Lijuan; Li, Xiaoli

2015-01-01

Objective We wished to determine the prevalence of fever as one of the first symptoms of the enthesitis-related arthritis (ERA) subtype of juvenile idiopathic arthritis. Also, we wished to ascertain if ERA patients with fever at disease onset differed from those without fever. Methods Consecutive cases of ERA were diagnosed and followed in a retrospective observational study from 1998 to 2013. Information about clinical/laboratory data, medications, magnetic resonance imaging (MRI), and disease activity during the study period was also recorded. Results A total of 146 consecutive ERA patients were assessed. Among them, 52 patients (35.6%) had fever as one of the first symptoms at disease onset. Compared with ERA patients without fever at disease onset, patients with fever had significantly more painful joints (3.5 vs. 2.8), more swollen joints (1.1 vs. 0.8), and more enthesitis (1.0 vs. 0.4) (p<0.05 for all comparisons). Patients with fever had significantly higher mean values of erythrocyte sedimentation rate, C-reactive protein, platelet count, and child health assessment questionnaire (CHAQ) scores (40.8 vs. 26.4 mm/h; 20.7 vs. 9.7 mg/dL; 353.2×109/L vs. 275.6×109/L; 1.0 vs. 0.8, respectively; all p<0.05). During two-year follow-up, CHAQ score, number of flares, as well as the number of patients treated with oral non-steroidal anti-inflammatory drugs, corticosteroids and combination therapy with disease-modifying anti-rheumatic drugs, were significantly higher in ERA patients with fever. Conclusions Fever was a frequent manifestation of ERA. ERA patients with fever had more active disease at disease onset and poorer outcomes than ERA patients without fever. PMID:26030261

The Use of Pediatric Ventricular Assist Devices in Children's Hospitals From 2000 to 2010: Morbidity, Mortality, and Hospital Charges.

PubMed

Mansfield, Robert T; Lin, Kimberly Y; Zaoutis, Theoklis; Mott, Antonio R; Mohamad, Zeinab; Luan, Xianqun; Kaufman, Beth D; Ravishankar, Chitra; Gaynor, J William; Shaddy, Robert E; Rossano, Joseph W

2015-07-01

The use of ventricular assist devices has increased dramatically in adult heart failure patients. However, the overall use, outcome, comorbidities, and resource utilization of ventricular assist devices in pediatric patients have not been well described. We sought to demonstrate that the use of ventricular assist devices in pediatric patients has increased over time and that mortality has decreased. A retrospective study of the Pediatric Health Information System database was performed for patients 20 years old or younger undergoing ventricular assist device placement from 2000 to 2010. None. Four hundred seventy-five pediatric patients were implanted with ventricular assist devices during the study period: 69 in 2000-2003 (era 1), 135 in 2004-2006 (era 2), and 271 in 2007-2010 (era 3). Median age at ventricular assist device implantation was 6.0 years (interquartile range, 0.5-13.8), and the proportion of children who were 1-12 years old increased from 29% in era 1 to 47% in era 3 (p = 0.002). The majority of patients had a diagnosis of cardiomyopathy; this increased from 52% in era 1 to 72% in era 3 (p = 0.003). Comorbidities included arrhythmias (48%), pulmonary hypertension (16%), acute renal failure (34%), cerebrovascular disease (28%), and sepsis/systemic inflammatory response syndrome (34%). Two hundred forty-seven patients (52%) underwent heart transplantation and 327 (69%) survived to hospital discharge. Hospital mortality decreased from 42% in era 1 to 25% in era 3 (p = 0.004). Median hospital length of stay increased (37 d [interquartile range, 12-64 d] in era 1 vs 69 d [interquartile range, 35-130] in era 3; p < 0.001) and median adjusted hospital charges increased ($630,630 [interquartile range, $227,052-$853,318] in era 1 vs $1,577,983 [interquartile range, $874,463-$2,280,435] in era 3; p < 0.001). Factors associated with increased mortality include age less than 1 year (odds ratio, 2.04; 95% CI, 1.01-3.83), acute renal failure (odds ratio, 2.1; 95% CI, 1.26-3.65), cerebrovascular disease (odds ratio, 2.1; 95% CI, 1.25-3.62), and extracorporeal membrane oxygenation (odds ratio, 3.16; 95% CI, 1.79-5.60). Ventricular assist device placement in era 3 (odds ratio, 0.3; 95% CI, 0.15-0.57) and a diagnosis of cardiomyopathy (odds ratio, 0.5; 95% CI, 0.32-0.84), were associated with decreased mortality. Large-volume centers had lower mortality (odds ratio, 0.55; 95% CI, 0.34-0.88), lower use of extracorporeal membrane oxygenation, and higher charges. The use of ventricular assist devices and survival after ventricular assist device placement in pediatric patients have increased over time, with a concomitant increase in resource utilization. Age under 1 year, certain noncardiac morbidities, and the use of extracorporeal membrane oxygenation are associated with worse outcomes. Lower mortality was seen at larger volume ventricular assist device centers.

Novel analytical model for optimizing the pull-in voltage in a flexured MEMS switch incorporating beam perforation effect

NASA Astrophysics Data System (ADS)

Guha, K.; Laskar, N. M.; Gogoi, H. J.; Borah, A. K.; Baishnab, K. L.; Baishya, S.

2017-11-01

This paper presents a new method for the design, modelling and optimization of a uniform serpentine meander based MEMS shunt capacitive switch with perforation on upper beam. The new approach is proposed to improve the Pull-in Voltage performance in a MEMS switch. First a new analytical model of the Pull-in Voltage is proposed using the modified Mejis-Fokkema capacitance model taking care of the nonlinear electrostatic force, the fringing field effect due to beam thickness and etched holes on the beam simultaneously followed by the validation of same with the simulated results of benchmark full 3D FEM solver CoventorWare in a wide range of structural parameter variations. It shows a good agreement with the simulated results. Secondly, an optimization method is presented to determine the optimum configuration of switch for achieving minimum Pull-in voltage considering the proposed analytical mode as objective function. Some high performance Evolutionary Optimization Algorithms have been utilized to obtain the optimum dimensions with less computational cost and complexity. Upon comparing the applied algorithms between each other, the Dragonfly Algorithm is found to be most suitable in terms of minimum Pull-in voltage and higher convergence speed. Optimized values are validated against the simulated results of CoventorWare which shows a very satisfactory results with a small deviation of 0.223 V. In addition to these, the paper proposes, for the first time, a novel algorithmic approach for uniform arrangement of square holes in a given beam area of RF MEMS switch for perforation. The algorithm dynamically accommodates all the square holes within a given beam area such that the maximum space is utilized. This automated arrangement of perforation holes will further improve the computational complexity and design accuracy of the complex design of perforated MEMS switch.

The Modular Modeling System (MMS): A modeling framework for water- and environmental-resources management

USGS Publications Warehouse

Leavesley, G.H.; Markstrom, S.L.; Viger, R.J.

2004-01-01

The interdisciplinary nature and increasing complexity of water- and environmental-resource problems require the use of modeling approaches that can incorporate knowledge from a broad range of scientific disciplines. The large number of distributed hydrological and ecosystem models currently available are composed of a variety of different conceptualizations of the associated processes they simulate. Assessment of the capabilities of these distributed models requires evaluation of the conceptualizations of the individual processes, and the identification of which conceptualizations are most appropriate for various combinations of criteria, such as problem objectives, data constraints, and spatial and temporal scales of application. With this knowledge, "optimal" models for specific sets of criteria can be created and applied. The U.S. Geological Survey (USGS) Modular Modeling System (MMS) is an integrated system of computer software that has been developed to provide these model development and application capabilities. MMS supports the integration of models and tools at a variety of levels of modular design. These include individual process models, tightly coupled models, loosely coupled models, and fully-integrated decision support systems. A variety of visualization and statistical tools are also provided. MMS has been coupled with the Bureau of Reclamation (BOR) object-oriented reservoir and river-system modeling framework, RiverWare, under a joint USGS-BOR program called the Watershed and River System Management Program. MMS and RiverWare are linked using a shared relational database. The resulting database-centered decision support system provides tools for evaluating and applying optimal resource-allocation and management strategies to complex, operational decisions on multipurpose reservoir systems and watersheds. Management issues being addressed include efficiency of water-resources management, environmental concerns such as meeting flow needs for endangered species, and optimizing operations within the constraints of multiple objectives such as power generation, irrigation, and water conservation. This decision support system approach is being developed, tested, and implemented in the Gunni-son, Yakima, San Juan, Rio Grande, and Truckee River basins of the western United States. Copyright ASCE 2004.

The environmental conditionings of the location of primeval settlements in the Wieprz River valley

NASA Astrophysics Data System (ADS)

Kozieł, Marcin; Kozieł, Wojciech

2012-01-01

The Wieprz River along the section currently occupied by the Nadwieprzański Landscape Park (NLP) constituted a convenient place of human settlement from the moment of retreat of the last ice sheet. Depending on the types of economy preferred by representatives of individual archaeological cultures, the river valley from Spiczyn to Dorohucza offered continuous access to water. This obviously gained additional importance from the moment of appearance of Neolithic cultures, particularly the Globular Amphora culture and Corded Ware culture with semi-nomadic style of life, dealing with breeding. Neolithic hunters-gatherers exploited the animal resources available in the river and its vicinity. The further role of fishing, i.e. providing a diet element or supplementation already in the conditions of agricultural-breeding economy, seems to be evidenced by findings of fishing hooks at Lusatian and Wielbark sites. Another factor affecting the location of settlements in NLP was also its close vicinity to the crops of the Rejowiec flint. According to archaeologists, this is particularly obvious in the case of the Late Palaeolithic and the turn of the Neolithic and Bronze Age. The communication function of the river could also be of importance: in the case of seasonal animal migrations of animals and hunters (Late Palaeolithic); livestock and shepherds (Globular Amphora culture and Corded Ware culture); or people alone (migration of the population of the Wielbark culture to the Red Sea). The fact that a commercial trail fragment was located along the Wieprz River is probably evidenced by the abundance of import from various parts of Europe at site 53 in Spiczyn. Fertile soils (black soils, silt-peat soils) prevailing in the valley also favoured the settlement of cultures with an agricultural-breeding model of economy, providing good conditions for horticulture. Meadows near the river could be used as pastures.

Five decades of promotion techniques in cigarette advertising: a longitudinal content analysis.

PubMed

Paek, Hye-Jin; Reid, Leonard N; Jeong, Hyun Ju; Choi, Hojoon; Krugman, Dean

2012-01-01

This study examines frequencies and types of promotion techniques featured in five decades of cigarette advertising relative to five major smoking eras. Analysis of 1,133 cigarette advertisements collected through multistage sampling of 1954 through 2003 issues of three youth-oriented magazines found that 7.6% of the analyzed ads featured at least one promotion technique. Across smoking eras the proportion of promotion in the ads steadily increased from 1.6% in the "pre-broadcast ban era" to 10.9% in the "the pre-Master Settlement Agreement (MSA) era" and 9% in "post-MSA era." The increased use of sponsorships/events in cigarette ads for youth-oriented brands warrants more attention from tobacco control experts and government regulators.

The environment of the last hunters-gatherers and first agro-pastoralists in the western Mediterranean region, between the Rhone and the Northern Apennines (7th - 6th millennium cal. BCE): Attractiveness of the landscape units and settlement patterns

NASA Astrophysics Data System (ADS)

Battentier, Janet; Binder, Didier; Guillon, Sebastien; Maggi, Roberto; Negrino, Fabio; Sénépart, Ingrid; Tozzi, Carlo; Théry-Parisot, Isabelle; Delhon, Claire

2018-03-01

In the north western Mediterranean, in the area between the Rhone River and the Northern Apennines, the last Mesolithic societies (Castelnovian) and the first Neolithic societies (Impressed Ware or Impressa) coexisted during the first half of the 6th millennium cal. BCE (Before Common Era). Linking the two settlement distribution patterns (mainly high lands and low lands for the Castelnovian versus Mediterranean coastal areas for the Impressa) to their specific environmental backgrounds during that period of coexistence enables us to document the attractiveness of the various available landscape units as a function of the subsistence practices (hunting, fishing and gathering versus agro-pastoralism). Pollen and charcoal data from 41 archaeological sites along with contemporaneous natural (off archaeological sites) sequences (hereafter referred to as "off-site sequences") from three windows (Provence/Western Liguria, the middle Rhone valley/Prealps and Southern Alps, Eastern Liguria/Northern Apennines) were examined in order to reconstruct the vegetal landscape in the surroundings of the Mesolithic and Neolithic settlements between 6500 and 5400 cal. BCE. The importance of environmental versus cultural factors in the settlement preferences of both groups is discussed in order to document our reflection concerning non-consensual issues, such as the existence of interaction or avoidance behaviours or the sharing (or not) of parts or all of the territory and of its natural resources. The results notably highlight the expansion of fir forests that, based on ecological and accessibility criteria, could be considered as rather inauspicious for settlement and hunting as well as for pastoral activities. This expansion may have influenced the settlement patterns of both cultural complexes, leading populations to locate their settlements principally within landscape units that remained clear of extensive fir forests. It appears that, despite being motivated by the prevailing subsistence activities, the choice of an area of land for settlement is deeply guided by various other cultural factors which are less directly dependent upon natural resources. Thus, in an area providing a large range of possibilities, the landscape in which the groups establish themselves could be considered as just one of many cultural characteristics.

Six Decades of Flight Research: Dryden Flight Research Center, 1946 - 2006 [DVD

NASA Technical Reports Server (NTRS)

Fisher, David F.; Parcel, Steve

2007-01-01

This DVD contains an introduction by Center Director Kevin Peterson, two videos on the history of NASA Dryden Flight Research Center and a bibliography of NASA Dryden Flight Research Center publications from 1946 through 2006. The NASA Dryden 60th Anniversary Summary Documentary video is narrated by Michael Dorn and give a brief history of Dryden. The Six Decades of Flight Research at NASA Dryden lasts approximately 75 minutes and is broken up in six decades: 1. The Early X-Plane Era; 2. The X-15 Era; 3. The Lifting Body Era; 4. The Space Shuttle Era; 5. The High Alpha and Thrust Vectoring Era; and 6. The technology Demonstration Era. The bibliography provides citations for NASA Technical Reports and Conference Papers, Tech Briefs, Contractor Reports, UCLA Flight Systems Research Center publications and Dryden videos. Finally, a link is provided to the NASA Dryden Gallery that features video clips and photos of the many unique aircraft flown at NASA Dryden and its predecessor organizations.

Biodiversity, ecosystem functions and services in environmental risk assessment: introduction to the special issue.

PubMed

Schäfer, Ralf B

2012-01-15

This Special Issue focuses on the questions if and how biodiversity, ecosystem functions and resulting services could be incorporated into the Ecological Risk Assessment (ERA). Therefore, three articles provide a framework for the integration of ecosystem services into ERA of soils, sediments and pesticides. Further articles demonstrate ways how stakeholders can be integrated into an ecosystem service-based ERA for soils and describe how the current monitoring could be adapted to new assessment endpoints that are directly linked to ecosystem services. Case studies show that the current ERA may not be protective for biodiversity, ecosystem functions and resulting services and that both pesticides and salinity currently adversely affect ecosystem functions in the field. Moreover, ecological models can be used for prediction of new protection goals and could finally support their implementation into the ERA. Overall, the Special Issue stresses the urgent need to enhance current procedures of ERA if biodiversity, ecosystem functions and resulting services are to be protected. Copyright © 2011 Elsevier B.V. All rights reserved.

Safety, efficacy, and cost of intraoperative indocyanine green angiography compared to intraoperative catheter angiography in cerebral aneurysm surgery.

PubMed

Hardesty, Douglas A; Thind, Harjot; Zabramski, Joseph M; Spetzler, Robert F; Nakaji, Peter

2014-08-01

Intraoperative angiography in cerebrovascular neurosurgery can drive the repositioning or addition of aneurysm clips. Our institution has switched from a strategy of intraoperative digital subtraction angiography (DSA) universally, to a strategy of indocyanine green (ICG) videoangiography with DSA on an as-needed basis. We retrospectively evaluated whether the rates of perioperative stroke, unexpected postoperative aneurysm residual, or parent vessel stenosis differed in 100 patients from each era (2002, "DSA era"; 2007, "ICG era"). The clip repositioning rate for neck residual or parent vessel stenosis did not differ significantly between the two eras. There were no differences in the rate of perioperative stroke or rate of false-negative studies. The per-patient cost of intraoperative imaging within the DSA era was significantly higher than in the ICG era. The replacement of routine intraoperative DSA with ICG videoangiography and selective intraoperative DSA in cerebrovascular aneurysm surgery is safe and effective. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

A qualitative study to understand the barriers and enablers in implementing an enhanced recovery after surgery program.

PubMed

Pearsall, Emily A; Meghji, Zahida; Pitzul, Kristen B; Aarts, Mary-Anne; McKenzie, Marg; McLeod, Robin S; Okrainec, Allan

2015-01-01

Explore the barriers and enablers to adoption of an Enhanced Recovery after Surgery (ERAS) program by the multidisciplinary perioperative team responsible for the care of elective colorectal surgical patients. ERAS programs include perioperative interventions that when used together have led to decreased length of stay while increasing patient recovery and satisfaction. Despite the known benefits of ERAS programs, uptake remains slow. Semistructured interviews were conducted with general surgeons, anesthesiologists, and ward nurses at 7 University of Toronto-affiliated hospitals to identify potential barriers and enablers to adoption of 18 ERAS interventions. Grounded theory was used to thematically analyze the transcribed interviews. Nineteen general surgeons, 18 anesthesiologists, and 18 nurses participated. The mean time of each interview was 18 minutes. Lack of manpower, poor communication and collaboration, resistance to change, and patient factors were cited by most as barriers. Discipline-specific issues were identified although most related to resistance to change. Overall, interviewees were supportive of implementation of a standardized ERAS program and agreed that a standardized guideline based on best evidence; standardized order sets; and education of the staff, patients, and families are essential. Multidisciplinary perioperative staff supported the implementation of an ERAS program at the University of Toronto-affiliated hospitals. However, major barriers were identified, including the need for patient education, increased communication and collaboration, and better evidence for ERAS interventions. Identifying these barriers and enablers is the first step toward successfully implementing an ERAS program.

Ten years' evaluation of potential pancreas donors in São Paulo, Brazil.

PubMed

Pinheiro, R S; Rocha-Santos, V; Pecora, R A; Macedo, R A; Nacif, L S; Andraus, W; David, A I; Pantanali, C A; Benites, C M; d'Albuquerque, L A C

2014-01-01

Pancreas transplantation is a treatment for advanced type 1 diabetes and offers significant improvement in quality of life. Recent advances in surgical techniques and immunosuppression regimes lead to good outcomes. However, despite significant higher rates of multiorgan donors in Brazil, pancreas transplantation seems to have remained stable. This study aimed to investigate the acceptance rate of potential pancreas donors in the past 10 years in São Paulo State. We retrospectively evaluated potential pancreas donors characteristics and its acceptance rate in São Paulo State in the past 10 years. We divided this period into 2 eras: 1st era from January 2003 to January 2008; and 2nd era from January 2008 to January 2013. Data were obtained from São Paulo's government official website. During the whole period, 5,005 deceased donors of all ages were available for pancreas transplantation. According to eras, we had 1,588 donors in the 1st and 3,417 in the 2nd era. In the 2nd era, donors >49 years old were significantly more common (P < .001). Blood test abnormalities, donor comorbidities, and high dosage of vasopressors also were significantly higher in the 2nd era. Rate of graft acceptance had a significant decrease in the 2nd era, from 46.4% to 25% (P < .05). Despite greater organ availability, pancreas transplantations performed in São Paulo State remained stable. Rate of graft acceptance is dramatically lower in more recent years. Copyright © 2014 Elsevier Inc. All rights reserved.

What happens when the patent ductus arteriosus is treated less aggressively in very low birth weight infants?

PubMed

Kaempf, J W; Wu, Y X; Kaempf, A J; Kaempf, A M; Wang, L; Grunkemeier, G

2012-05-01

It remains unclear whether indomethacin (INDO) and/or surgical ligation (LIGATE) are necessary to improve outcomes in premature infants with a patent ductus arteriosus (PDA). We have adopted a conservative approach to PDA management that emphasizes waiting for spontaneous closure unless certain cardiorespiratory distress criteria are met. This was a before-after observational study in infants born 501 to 1,500 g in two distinct epochs. Era 1 (January 2005 to December 2007) featured traditional management with INDO and LIGATE used early to close all moderate and large PDAs in infants receiving any respiratory support. Era 2 (January 2008 to June 2009) emphasized modest fluid restriction, watchful waiting and limited INDO and LIGATE to only those infants with large PDAs who met certain cardiorespiratory distress criteria. Era 1 included 139 infants with a PDA, mean (s.d.) gestational age 27.5 (2) weeks; Era 2 72 infants, mean (s.d.) gestational age 27.5 (2) weeks. In Era 2, INDO use significantly decreased (79% of infants to 26%, P<0.001), and 28 day total fluids decreased (140 vs. 130  ml kg(-1) day(-1), P<0.001). LIGATE rate was 45% in Era 1, 33% in Era 2 (P=0.11). There were no significant differences in supplemental oxygen, nasal continuous positive airway pressure, or mechanical ventilation days. There were no significant differences in mortality or individual morbidities. The combined outcome of chronic lung disease (CLD) or mortality after Day 7 significantly increased (Era 1, 40%, Era 2, 54%, P=0.04). More infants were discharged home with a PDA in Era 2, but most resolved spontaneously and the need for closure therapy after discharge from the neonatal intensive care unit (NICU) did not increase. Multiple regression analysis demonstrated Era 2 management did not predict an increased risk of one or more interlinked morbidities. Tolerance of the PDA with watchful waiting for spontaneous closure, modest fluid reduction, and less INDO use is a reasonable treatment strategy that is not associated with significant changes in NICU mortality or individual morbidities. We did note an increase in the combined outcome of CLD or mortality after Day 7, thus our investigation supports the urgency of a randomized controlled trial comparing traditional PDA management with a true control group similar to our Era 2 management to answer important questions of short and long-term outcomes.

Evaluation of ERA-Interim precipitation data in complex terrain

NASA Astrophysics Data System (ADS)

Gao, Lu; Bernhardt, Matthias; Schulz, Karsten

2013-04-01

Precipitation controls a large variety of environmental processes, which is an essential input parameter for land surface models e.g. in hydrology, ecology and climatology. However, rain gauge networks provides the necessary information, are commonly sparse in complex terrains, especially in high mountainous regions. Reanalysis products (e.g. ERA-40 and NCEP-NCAR) as surrogate data are increasing applied in the past years. Although they are improving forward, previous studies showed that these products should be objectively evaluated due to their various uncertainties. In this study, we evaluated the precipitation data from ERA-Interim, which is a latest reanalysis product developed by ECMWF. ERA-Interim daily total precipitation are compared with high resolution gridded observation dataset (E-OBS) at 0.25°×0.25° grids for the period 1979-2010 over central Alps (45.5-48°N, 6.25-11.5°E). Wet or dry day is defined using different threshold values (0.5mm, 1mm, 5mm, 10mm and 20mm). The correspondence ratio (CR) is applied for frequency comparison, which is the ratio of days when precipitation occurs in both ERA-Interim and E-OBS dataset. The result shows that ERA-Interim captures precipitation occurrence very well with a range of CR from 0.80 to 0.97 for 0.5mm to 20mm thresholds. However, the bias of intensity increases with rising thresholds. Mean absolute error (MAE) varies between 4.5 mm day-1 and 9.5 mm day-1 in wet days for whole area. In term of mean annual cycle, ERA-Interim almost has the same standard deviation of the interannual variability of daily precipitation with E-OBS, 1.0 mm day-1. Significant wet biases happened in ERA-Interim throughout warm season (May to August) and dry biases in cold season (November to February). The spatial distribution of mean annual daily precipitation shows that ERA-Interim significant underestimates precipitation intensity in high mountains and northern flank of Alpine chain from November to March while pronounced overestimate in the southern flank of Alps. The poor topographical and flow related characteristic representation of ERA-Interim model is possibly responsible for the bias. Particularly, the mountain block effect of moisture is weak captured. The comparison demonstrates that ERA-Interim precipitation intensity needs bias correction for further alpine climate studies, although it reasonably captures precipitation frequency. This critical evaluation not only diagnosed the data quality of ERA-Interim, but also provided the evidence for reanalysis products downscaling and bias correction in complex terrain.

Visualizing estrogen receptor-a-expressing neurons using a new ERa-ZsGreen reporter mouse line

USDA-ARS?s Scientific Manuscript database

A variety of biological functions of estrogens, including regulation of energy metabolism, are mediated by neurons expressingestrogen receptor-a (ERa) in the brain. However, complex intracellular processes in these ERa-expressing neurons are difficult to unravel, due to the lack of strategy to visua...

76 FR 62793 - Combined Notice Of Filings #1

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-11

.... Docket Numbers: ER11-4676-000. Applicants: Puget Sound Energy, Inc. Description: Puget Sound Energy, Inc...: NextEra Energy Montezuma II Wind, LLC. Description: NextEra Energy Montezuma II Wind, LLC submits tariff filing per 35.12: NextEra Energy Montezuma II Wind, LLC Market-Based Rate Tariff to be effective...

A New Era for Research Education in Australia?

ERIC Educational Resources Information Center

Marsh, Helene; Smith, Bradley; King, Max; Evans, Terry

2012-01-01

Use of the Australian research assessment exercise, Excellence in Research for Australia (ERA) to influence the policy and practice of research education in Australia will undoubtedly have many consequences, some of them unintended and potentially deleterious. ERA is a retrospective measure of research quality; research education is prospective.…

[Attenuated rabies virus, ERA strain, in cattle and dogs vaccinated with multiple doses].

PubMed

Titoli, F; Pestalozza, S; Irsara, A; Palliola, E; Frescura, T; Civardi, A

1982-01-01

Investigation on the vaccination of 18 cattle and 5 dogs against rabies is reported. Each animal received multiple doses of ERA strain vaccine intramuscularly in the gluteal or masseter region. The saliva, the brain and salivary glands of the vaccinated animals were examined to detect the presence of ERA virus using immunofluorescent test and mouse inoculation. The virus was never found in the saliva and organs of treated animals. Circulating antibodies against ERA rabies virus were detected in all vaccinated cattle and dogs.

Growth of semimetallic ErAs films epitaxially embedded in GaAs

NASA Astrophysics Data System (ADS)

Crook, Adam M.; Nair, Hari P.; Lee, Jong H.; Ferrer, Domingo A.; Akinwande, Deji; Bank, Seth R.

2011-10-01

We present models for the growth and electrical conductivity of ErAs films grown with the nanoparticle-seeded film growth technique. This growth mode overcomes the mismatch in rotational symmetry between the rocksalt ErAs crystal structure and the zincblende GaAs crystal structure. This results in films of ErAs grown through a thin film of GaAs that preserves the symmetry of the substrate. The conductivity of the films, as a function of film thickness, are investigated and a surface roughness model is used to explain observed trends. Transmission electron micrographs confirm the suppression of anti-phase domains. A simple diffusion model is developed to describe the diffusion and incorporation of surface erbium into subsurface ErAs layers and predict potential failure mechanisms of the growth method.

Stacking InAs quantum dots over ErAs semimetal nanoparticles on GaAs (0 0 1) using molecular beam epitaxy

NASA Astrophysics Data System (ADS)

Zhang, Yuanchang; Eyink, Kurt G.; Grazulis, Lawrence; Hill, Madelyn; Peoples, Joseph; Mahalingam, Krishnamurthy

2017-11-01

Hybrid nanostructures are known to elicit an enhanced optical response. We study the directed alignment of ErAs metal nanoparticle (NP) and InAs quantum dot (QD) using molecular beam eptaxy (MBE) in a GaAs matrix. Due to high surface free energy caused by the crystal structure difference, overgrowth of an ErAs NP with GaAs forms a depression that condenses subsequent InAs adatoms to form an inverted QD self-aligned to the underlying ErAs NP. The ErAs NP growth, GaAs overgrowth, and InAs QD deposition were carefully controlled and studied with transmission electron microscopy (TEM) and atomic force microscopy (AFM) to investigate their effects on the QD-NP alignment.

On the beginning of the Christian era (A.D.) and the miscount of Dionysius

NASA Astrophysics Data System (ADS)

Umlenski, Vasil

The beginning of the Christian era (A. D.; common era; our era; new era) is connected with Christ's birth. It is the usual practice that Dionysius Exiguus made a miscount by determining the years of Jesus' birth and Crucifix. In the present work we make an attempt to determine this miscount through astronomical computations of the newmoons (The Crucifix is on Friday, the day before the Jewish Passover i.e. on the 14-th day of the Moon). It was found that the miscount of Dionysius is 9 years regarding Christmas and 11 years regarding the Resurrection (the first Easter). The obtained results are in accordance with St. John's Gospel and with the information of competent ancient annalists as Eusebius of Caesarea.

An eigensystem realization algorithm using data correlations (ERA/DC) for modal parameter identification

NASA Technical Reports Server (NTRS)

Juang, Jer-Nan; Cooper, J. E.; Wright, J. R.

1987-01-01

A modification to the Eigensystem Realization Algorithm (ERA) for modal parameter identification is presented in this paper. The ERA minimum order realization approach using singular value decomposition is combined with the philosophy of the Correlation Fit method in state space form such that response data correlations rather than actual response values are used for modal parameter identification. This new method, the ERA using data correlations (ERA/DC), reduces bias errors due to noise corruption significantly without the need for model overspecification. This method is tested using simulated five-degree-of-freedom system responses corrupted by measurement noise. It is found for this case that, when model overspecification is permitted and a minimum order solution obtained via singular value truncation, the results from the two methods are of similar quality.

Outcomes after implementing the enhanced recovery after surgery protocol for patients undergoing tuberculous empyema operations.

PubMed

Xia, Zhaohua; Qiao, Kun; Wang, Haijiang; Ning, Xinzhong; He, Jianxing

2017-07-01

Enhanced recovery after surgery (ERAS) protocols provide recommendations for care in various surgical fields. However, there is scarce information on the application of these protocols in tuberculous empyema surgery. The purpose of this research is to evaluate the outcomes of ERAS recommendations for patients who received tuberculous empyema surgery. A retrospective analysis was performed on patients who underwent tuberculous empyema surgery in our hospital from March 2011 to March 2016. The patients were divided into an ERAS group and a conventional control group. The main outcome measure was the postoperative median length of stay (including readmissions). Principles related to ERAS were documented, and the postoperative median hospital stay was analyzed statistically between the two groups. A total of 92 patients underwent 93 consecutive tuberculous empyema surgical treatments. The postoperative fasting time, chest tube duration, and length of stay were shorter in the ERAS group compared with the control group. The volume of chest tube drainage in the ERAS group was significantly smaller than that of the control group. No statistical differences were observed in the postoperative complications and reasons for readmission between the two groups. Application of ERAS recommendations in patients receiving tuberculous empyema operations decreased the length of stay and chest tube drainage compared to the control group.

Assessment of Precipitation Trends over Europe by Comparing ERA-20C with a New Homogenized Observational GPCC Dataset

NASA Astrophysics Data System (ADS)

Rustemeier, E.; Ziese, M.; Meyer-Christoffer, A.; Finger, P.; Schneider, U.; Becker, A.

2015-12-01

Reliable data is essential for robust climate analysis. The ERA-20C reanalysis was developed during the projects ERA-CLIM and ERA-CLIM2. These projects focus on multi-decadal reanalyses of the global climate system. To ensure data quality and provide end users with information about uncertainties in these products, the 4th work package of ERA_CLIM2 deals with the quality assessment of the products including quality control and error estimation.In doing so, the monthly totals of the ERA-20C reanalysis are compared to two corresponding Global Precipitation Climatology Centre (GPCC) products; the Full Data Reanalysis Version 7 and the new HOMogenized PRecipitation Analysis of European in-situ data (HOMPRA Europe).ERA-20C reanalysis was produced based on ECMWFs IFS version Cy38r1 with a spatial resolution of about 125 km. It covers the time period 1900 to 2010. Only surface observations are assimilated namely marine winds and pressure. This allows the comparison with independent, not assimilated data. The GPCC Full Data Reanalysis Version 7 comprises monthly land-surface precipitation from approximately 75,000 rain-gauges covering the time period 1901-2013. For this paper, the version with 1° resolution is utilized. For trend analysis, a monthly European subset of the ERA-20C reanalysis is investigated spanning the years 1951-2005. The European subset will be compared to a new homogenized GPCC data set HOMPRA Europe. The latter is based on a collective of 5373 homogenized monthly rain gauge time series, carefully chosen from the GPCC archive of precipitation data.For the spatial and temporal evaluation of ERA-20C, global scores on monthly, seasonal and annual time scales are calculated. These include contingency table scores, correlation, along with spatial scores such as the fractional skill score. Unsurprisingly regions with strongest deviations are those of data scarcity, mountainous regions with their luv and lee effects, and monsoon regions. They all exhibit strong biases throughout their series, and severe shifts in the means. The new HOMPRA Europe data set is useful in particular for trend analysis. Therefore it is compared to a monthly European subset of the ERA-20C reanalysis for the same period, i.e. the years 1951-2005, to study the ERA-20C capability in reproducing observed trends across Europe.

Role of protein farnesylation events in the ABA-mediated regulation of the Pinoresinol-Lariciresinol Reductase 1 (LuPLR1) gene expression and lignan biosynthesis in flax (Linum usitatissimum L.).

PubMed

Corbin, Cyrielle; Decourtil, Cédric; Marosevic, Djurdjica; Bailly, Marlène; Lopez, Tatiana; Renouard, Sullivan; Doussot, Joël; Dutilleul, Christelle; Auguin, Daniel; Giglioli-Guivarc'h, Nathalie; Lainé, Eric; Lamblin, Frédéric; Hano, Christophe

2013-11-01

A Linum usitatissimum LuERA1 gene encoding a putative ortholog of the ERA1 (Enhanced Response to ABA 1) gene of Arabidopsis thaliana (encoding the beta subunit of a farnesyltransferase) was analyzed in silico and for its expression in flax. The gene and the protein sequences are highly similar to other sequences already characterized in plants and all the features of a farnesyltransferase were detected. Molecular modeling of LuERA1 protein confirmed its farnesyltransferase nature. LuERA1 is expressed in the vegetative organs and also in the outer seedcoat of the flaxseed, where it could modulate the previously observed regulation operated by ABA on lignan synthesis. This effect could be mediated by the regulation of the transcription of a key gene for lignan synthesis in flax, the LuPLR1 gene, encoding a pinoresinol lariciresinol reductase. The positive effect of manumycin A, a specific inhibitor of farnesyltransferase, on lignan biosynthesis in flax cell suspension systems supports the hypothesis of the involvement of such an enzyme in the negative regulation of ABA action. In Arabidopsis, ERA1 is able to negatively regulate the ABA effects and the mutant era1 has an enhanced sensitivity to ABA. When expressed in an Arabidopsis cell suspension (heterologous system) LuERA1 is able to reverse the effect of the era1 mutation. RNAi experiments in flax targeting the farnesyltransferase β-subunit encoded by the LuERA1 gene led to an increase LuPLR1 expression level associated with an increased content of lignan in transgenic calli. Altogether these results strongly suggest a role of the product of this LuERA1 gene in the ABA-mediated upregulation of lignan biosynthesis in flax cells through the activation of LuPLR1 promoter. This ABA signaling pathway involving ERA1 probably acts through the ABRE box found in the promoter sequence of LuPLR1, a key gene for lignan synthesis in flax, as demonstrated by LuPLR1 gene promoter-reporter experiments in flax cells using wild type and mutated promoter sequences. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Generation of a novel live rabies vaccine strain with a high level of safety by introducing attenuating mutations in the nucleoprotein and glycoprotein.

PubMed

Nakagawa, Keisuke; Nakagawa, Kento; Omatsu, Tsutomu; Katayama, Yukie; Oba, Mami; Mitake, Hiromichi; Okada, Kazuma; Yamaoka, Satoko; Takashima, Yasuhiro; Masatani, Tatsunori; Okadera, Kota; Ito, Naoto; Mizutani, Tetsuya; Sugiyama, Makoto

2017-10-09

The current live rabies vaccine SAG2 is attenuated by only one mutation (Arg-to-Glu) at position 333 in the glycoprotein (G333). This fact generates a potential risk of the emergence of a pathogenic revertant by a back mutation at this position during viral propagation in the body. To circumvent this risk, it is desirable to generate a live vaccine strain highly and stably attenuated by multiple mutations. However, the information on attenuating mutations other than that at G333 is very limited. We previously reported that amino acids at positions 273 and 394 in the nucleoprotein (N273/394) (Leu and His, respectively) of fixed rabies virus Ni-CE are responsible for the attenuated phenotype by enhancing interferon (IFN)/chemokine gene expressions in infected neural cells. In this study, we found that amino acid substitutions at N273/394 (Phe-to-Leu and Tyr-to-His, respectively) attenuated the pathogenicity of the oral live vaccine ERA, which has a virulent-type Arg at G333. Then we generated ERA-N273/394-G333 attenuated by the combination of the above attenuating mutations at G333 and N273/394, and checked its safety. Similar to the ERA-G333, which is attenuated by only the mutation at G333, ERA-N273/394-G333 did not cause any symptoms in adult mice after intracerebral inoculation, indicating a low level of residual pathogenicity of ERA-N273/394-G333. Further examination revealed that infection with ERA-N273/394-G333 induces IFN-β and CXCL10 mRNA expressions more strongly than ERA-G333 infection in a neuroblastoma cell line. Importantly, we found that the ERA-N273/394-G333 stain has a lower risk for emergence of a pathogenic revertant than does the ERA-G333. These results indicate that ERA-N273/394-G333 has a potential to be a promising candidate for a live rabies vaccine strain with a high level of safety. Copyright © 2017 Elsevier Ltd. All rights reserved.

Bacterial Survival in Laundered Fabrics

PubMed Central

Walter, William G.; Schillinger, John E.

1975-01-01

Bacterial survival was determined in linens (i) inoculated with Staphylococcus aureus (ii), taken from hospital isolation patients' beds, and (iii) used by students in their homes. Two different washers using temperatures of 38, 49, 54 and 60 C, respectively, for different times were employed along with a commercial tumbler dryer. Findings, after macerating the linens in a Waring blender and enumerating on nonselective media, indicate that acceptable levels of survivors can be achieved in motel and hotel linens by an 8- to 10-min wash cycle at 54 C followed by adequate drying. However, it is recommended that a wash cycle with 60 C for 10 to 13 min be employed for linens in health care factilities. The microbial significance of various laundering practices is discussed. PMID:1090256

Reducing firing of an early pottery making kiln at Batán Grande, Peru: A Mössbauer study

NASA Astrophysics Data System (ADS)

Wagner, U.; Gebhard, R.; Häusler, W.; Hutzelmann, T.; Riederer, J.; Shimada, I.; Sosa, J.; Wagner, F. E.

1999-11-01

Material from field firing experiments using a 2,700-year old Formative kiln at Batán Grande, Peru, was studied by X-ray diffraction and Mössbauer spectroscopy. The experiments explore the technology involved in producing the gray and black reduced ware for which Cupisnique and other Formative ceramics are justly known. During firing, the iron-bearing compounds in clays undergo characteristic changes which depend on kiln temperature and atmosphere. These changes can be observed in the Mössbauer spectra. By comparing spectra of an appropriate clay fired in field experiments and in the laboratory with the spectra of ancient ceramics, a description of Formative firing techniques in a reducing environment is attempted.

Accessibility and usability OCW data: The UTPL OCW.

PubMed

Rodríguez, Germania; Perez, Jennifer; Cueva, Samanta; Torres, Rommel

2017-08-01

This data article provides a data description on article entitled "A framework for improving web accessibility and usability of Open Course Ware sites" [3] This Data in Brief presents the data obtained from the accessibility and usability evaluation of the UTPL OCW. The data obtained from the framework evaluation consists of the manual evaluation of the standards criteria and the automatic evaluation of the tools Google PageSpeed and Google Analytics. In addition, this article presents the synthetized tables from standards that are used by the framework to evaluate the accessibility and usability of OCW, and the questionnaires required to extract the data. As a result, the article also provides the data required to reproduce the evaluation of other OCW.

A Standard Platform for Testing and Comparison of MDAO Architectures

NASA Technical Reports Server (NTRS)

Gray, Justin S.; Moore, Kenneth T.; Hearn, Tristan A.; Naylor, Bret A.

2012-01-01

The Multidisciplinary Design Analysis and Optimization (MDAO) community has developed a multitude of algorithms and techniques, called architectures, for performing optimizations on complex engineering systems which involve coupling between multiple discipline analyses. These architectures seek to efficiently handle optimizations with computationally expensive analyses including multiple disciplines. We propose a new testing procedure that can provide a quantitative and qualitative means of comparison among architectures. The proposed test procedure is implemented within the open source framework, OpenMDAO, and comparative results are presented for five well-known architectures: MDF, IDF, CO, BLISS, and BLISS-2000. We also demonstrate how using open source soft- ware development methods can allow the MDAO community to submit new problems and architectures to keep the test suite relevant.

Environmental risk assessment of chemicals and nanomaterials--The best foundation for regulatory decision-making?

PubMed

Syberg, Kristian; Hansen, Steffen Foss

2016-01-15

Environmental risk assessment (ERA) is often considered as the most transparent, objective and reliable decision-making tool for informing the risk management of chemicals and nanomaterials. ERAs are based on the assumption that it is possible to provide accurate estimates of hazard and exposure and, subsequently, to quantify risk. In this paper we argue that since the quantification of risk is dominated by uncertainties, ERAs do not provide a transparent or an objective foundation for decision-making and they should therefore not be considered as a "holy grail" for informing risk management. We build this thesis on the analysis of two case studies (of nonylphenol and nanomaterials) as well as a historical analysis in which we address the scientific foundation for ERAs. The analyses show that ERAs do not properly address all aspects of actual risk, such as the mixture effect and the environmentally realistic risk from nanomaterials. Uncertainties have been recognised for decades, and assessment factors are used to compensate for the lack of realism in ERAs. The assessment factors' values were pragmatically determined, thus lowering the scientific accuracy of the ERAs. Furthermore, the default choice of standard assay for assessing a hazard might not always be the most biologically relevant, so we therefore argue that an ERA should be viewed as a pragmatic decision-making tool among several, and it should not have a special status for informing risk management. In relation to other relevant decision-making tools we discuss the use of chemical alternative assessments (CAAs) and the precautionary principle. Copyright © 2015 Elsevier B.V. All rights reserved.

The Physical State of the Universe in the Planck Era

NASA Astrophysics Data System (ADS)

Riggs, Peter J.

2018-06-01

The Planck Era cannot be given an accurate mathematical description until the full theory of quantum gravity is available. However, some aspects of the physical state of the Planck Era can be revealed by order of the magnitude considerations which also have implications for the low entropy of the very early universe.

76 FR 36532 - Iberdrola Renewables, Inc., PacifiCorp, NextEra Energy Resources, LLC, Invenergy Wind North...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-22

... Renewables, Inc., PacifiCorp, NextEra Energy Resources, LLC, Invenergy Wind North America LLC, Horizon Wind...), Iberdrola Renewables, Inc., PacifiCorp, NextEra Energy Resources, LLC, Invenergy Wind North America LLC, and Horizon Wind Energy LLC (Complainants) filed a formal complaint against Bonneville Power Administration...

75 FR 74040 - Intent To Prepare an Environmental Impact Statement and To Conduct Scoping Meetings...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-30

... Proposed Project NextEra's proposed Project would consist of up to 100 wind turbine generators with a... roads. NextEra has secured leases with willing landowners for its wind generation turbines and related... substantial natural resources conflicts. NextEra's siting process for the wind turbine strings and associated...

The ERa-PI3K cascade in proopiomelanocortin progenitor neurons regulates feeding and glucose balance in female mice

USDA-ARS?s Scientific Manuscript database

Estrogens act upon estrogen receptor (ER)a to inhibit feeding and improve glucose homeostasis in female animals. However, the intracellular signals that mediate these estrogenic actions remain unknown. Here, we report that anorexigenic effects of estrogens are blunted in female mice that lack ERa sp...

Progressive-Era Resources on the World Wide Web.

ERIC Educational Resources Information Center

Howenstein, Amanda

1999-01-01

Provides a list of Progressive-era websites with the address and a detailed description of each of the websites. Includes topics such as the womens suffrage movement, the Triangle Shirtwaist Factory fire, the Prohibition, labor-management conflicts, the Hull House, the Chicago fire, Emma Goldman, Progressive-era entertainment, and the Worlds Fair.…

The Struggles of Women Industrial Workers To Improve Work Conditions in the Progressive Era.

ERIC Educational Resources Information Center

Barrett, Nancy J.

1999-01-01

Offers a lesson plan that addresses the working conditions endured by women in the Progressive Era and their struggles for womens rights in the workplace. Strives to demonstrate the similarities between the plights of the Progressive Era women to those of women workers in the 1990s. (CMK)

38 CFR 21.7045 - Eligibility based on involuntary separation, voluntary separation, or participation in the Post...

Code of Federal Regulations, 2013 CFR

2013-07-01

... involuntary separation, voluntary separation, or participation in the Post-Vietnam Era Veterans' Educational..., voluntary separation, or participation in the Post-Vietnam Era Veterans' Educational Assistance Program. An.... (Authority: 38 U.S.C. 3018B) (d) Alternate eligibility requirements for participants in the Post-Vietnam Era...

38 CFR 21.7045 - Eligibility based on involuntary separation, voluntary separation, or participation in the Post...

Code of Federal Regulations, 2014 CFR

2014-07-01

... involuntary separation, voluntary separation, or participation in the Post-Vietnam Era Veterans' Educational..., voluntary separation, or participation in the Post-Vietnam Era Veterans' Educational Assistance Program. An.... (Authority: 38 U.S.C. 3018B) (d) Alternate eligibility requirements for participants in the Post-Vietnam Era...

38 CFR 21.7045 - Eligibility based on involuntary separation, voluntary separation, or participation in the Post...

Code of Federal Regulations, 2011 CFR

2011-07-01

... involuntary separation, voluntary separation, or participation in the Post-Vietnam Era Veterans' Educational..., voluntary separation, or participation in the Post-Vietnam Era Veterans' Educational Assistance Program. An.... (Authority: 38 U.S.C. 3018B) (d) Alternate eligibility requirements for participants in the Post-Vietnam Era...

38 CFR 21.7045 - Eligibility based on involuntary separation, voluntary separation, or participation in the Post...

Code of Federal Regulations, 2012 CFR

2012-07-01

... involuntary separation, voluntary separation, or participation in the Post-Vietnam Era Veterans' Educational..., voluntary separation, or participation in the Post-Vietnam Era Veterans' Educational Assistance Program. An.... (Authority: 38 U.S.C. 3018B) (d) Alternate eligibility requirements for participants in the Post-Vietnam Era...

38 CFR 21.7045 - Eligibility based on involuntary separation, voluntary separation, or participation in the Post...

Code of Federal Regulations, 2010 CFR

2010-07-01

... involuntary separation, voluntary separation, or participation in the Post-Vietnam Era Veterans' Educational..., voluntary separation, or participation in the Post-Vietnam Era Veterans' Educational Assistance Program. An.... (Authority: 38 U.S.C. 3018B) (d) Alternate eligibility requirements for participants in the Post-Vietnam Era...