Cyber Warfare: New Character with Strategic Results

DTIC Science & Technology

2013-03-01

The advent of cyber warfare has sparked a debate amongst theorists as to whether timeless Clausewitzian principles remain true in the 21st century...Violence, uncertainty, and rationality still accurately depict the nature of cyber warfare , however, its many defining attributes and means by which...this style of warfare is conducted has definitively changed the character of war. Although cyber warfare is contested in the cyber domain, it often

Chemical warfare agent and biological toxin-induced pulmonary toxicity: could stem cells provide potential therapies?

PubMed

Angelini, Daniel J; Dorsey, Russell M; Willis, Kristen L; Hong, Charles; Moyer, Robert A; Oyler, Jonathan; Jensen, Neil S; Salem, Harry

2013-01-01

Chemical warfare agents (CWAs) as well as biological toxins present a significant inhalation injury risk to both deployed warfighters and civilian targets of terrorist attacks. Inhalation of many CWAs and biological toxins can induce severe pulmonary toxicity leading to the development of acute lung injury (ALI) as well as acute respiratory distress syndrome (ARDS). The therapeutic options currently used to treat these conditions are very limited and mortality rates remain high. Recent evidence suggests that human stem cells may provide significant therapeutic options for ALI and ARDS in the near future. The threat posed by CWAs and biological toxins for both civilian populations and military personnel is growing, thus understanding the mechanisms of toxicity and potential therapies is critical. This review will outline the pulmonary toxic effects of some of the most common CWAs and biological toxins as well as the potential role of stem cells in treating these types of toxic lung injuries.

The Art of Aerial Warfare

DTIC Science & Technology

2005-03-01

14 3 THE POLITICAL DIMENSIONS OF AERIAL WARFARE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 How Political Effects in...Aerial Warfare . . . . . . Outweigh Military Effects . . . . . . . . . . . . . . . 19 Political Targets Versus Military Targets . . . . . 22...34 4 MILITARY AND POLITICAL EFFECTS OF STRATEGIC ATTACK . . . . . . . . . . . . . . . . . . 35 The Premise of

Intrafamily and intragenomic conflicts in human warfare

PubMed Central

2017-01-01

Recent years have seen an explosion of multidisciplinary interest in ancient human warfare. Theory has emphasized a key role for kin-selected cooperation, modulated by sex-specific demography, in explaining intergroup violence. However, conflicts of interest remain a relatively underexplored factor in the evolutionary-ecological study of warfare, with little consideration given to which parties influence the decision to go to war and how their motivations may differ. We develop a mathematical model to investigate the interplay between sex-specific demography and human warfare, showing that: the ecology of warfare drives the evolution of sex-biased dispersal; sex-biased dispersal modulates intrafamily and intragenomic conflicts in relation to warfare; intragenomic conflict drives parent-of-origin-specific patterns of gene expression—i.e. ‘genomic imprinting’—in relation to warfare phenotypes; and an ecological perspective of conflicts at the levels of the gene, individual, and social group yields novel predictions as to pathologies associated with mutations and epimutations at loci underpinning human violence. PMID:28228515

Intrafamily and intragenomic conflicts in human warfare.

PubMed

Micheletti, Alberto J C; Ruxton, Graeme D; Gardner, Andy

2017-02-22

Recent years have seen an explosion of multidisciplinary interest in ancient human warfare. Theory has emphasized a key role for kin-selected cooperation, modulated by sex-specific demography, in explaining intergroup violence. However, conflicts of interest remain a relatively underexplored factor in the evolutionary-ecological study of warfare, with little consideration given to which parties influence the decision to go to war and how their motivations may differ. We develop a mathematical model to investigate the interplay between sex-specific demography and human warfare, showing that: the ecology of warfare drives the evolution of sex-biased dispersal; sex-biased dispersal modulates intrafamily and intragenomic conflicts in relation to warfare; intragenomic conflict drives parent-of-origin-specific patterns of gene expression-i.e. 'genomic imprinting'-in relation to warfare phenotypes; and an ecological perspective of conflicts at the levels of the gene, individual, and social group yields novel predictions as to pathologies associated with mutations and epimutations at loci underpinning human violence. © 2017 The Authors.

Replication Does Survive Information Warfare Attacks

DTIC Science & Technology

1997-01-01

warfare, storage jamming, unauthorized modification, Trojan horse 1 INTRODUCTION Ammann, Jajodia, McCollum, and Blaustein define information warfare as the...information warfare, and we adopt the latter term. To provide context, Amman et al. specifically do not consider Trojan horses within the database system...called internal jammers (McDermott and Goldschalg, 1996b)), but instead consider a wide range of attacks other than Trojan horses . Both groups agree that

14th Annual Expeditionary Warfare Conference

DTIC Science & Technology

2009-11-19

Untitled Document 2009expedition.html[5/12/2016 8:33:22 AM] 14th ANNUAL EXPEDITIONARY WARFARE CONFERENCE “Expeditionary Warfare in a Complex Joint...WWW.NDIA.ORG/MEETINGS/0700 “Expeditionary Warfare in a Complex Joint Operating Environment” BAY POINT MARRIOTT HOTEL, PANAMA CITY, FL...Focus: The purpose of the Quadrennial Defense Review (QDR) is to determine the nation’s defense strategy and establish a defense program for

Cyber Warfare: Protecting Military Systems

DTIC Science & Technology

2000-01-01

Software is a key component in nearly every critical system used by the Department of Defense. Attacking the software in a system- cyber warfare - is a...revolutionary method of pursuing war. This article describes various cyber warfare approaches and suggests methods to counter them.

Cyber Warfare as an Operational Fire

DTIC Science & Technology

2010-04-03

This paper explores cyber warfare as an option for creating operational fires effects. Initially, cyberspace is defined and explained from the...fires are defined and the advantages of their use are explained. From there, discussion focuses on how cyber warfare fulfills the purposes of...operational fires. Finally, the paper draws conclusions about the viability of cyber warfare as an operational fire and makes recommendations about how to prioritize the activities of the newly approved U.S. Cyber Command.

Chemical warfare agents

PubMed Central

Ganesan, K.; Raza, S. K.; Vijayaraghavan, R.

2010-01-01

Among the Weapons of Mass Destruction, chemical warfare (CW) is probably one of the most brutal created by mankind in comparison with biological and nuclear warfare. Chemical weapons are inexpensive and are relatively easy to produce, even by small terrorist groups, to create mass casualties with small quantities. The characteristics of various CW agents, general information relevant to current physical as well as medical protection methods, detection equipment available and decontamination techniques are discussed in this review article. A brief note on Chemical Weapons Convention is also provided. PMID:21829312

The evolution of human warfare.

PubMed

Pitman, George R

2011-01-01

Here we propose a new theory for the origins and evolution of human warfare as a complex social phenomenon involving several behavioral traits, including aggression, risk taking, male bonding, ingroup altruism, outgroup xenophobia, dominance and subordination, and territoriality, all of which are encoded in the human genome. Among the family of great apes only chimpanzees and humans engage in war; consequently, warfare emerged in their immediate common ancestor that lived in patrilocal groups who fought one another for females. The reasons for warfare changed when the common ancestor females began to immigrate into the groups of their choice, and again, during the agricultural revolution.

Glycoprotein Biochemistry--Some Clinical Aspects of Interest to Biochemistry Students.

ERIC Educational Resources Information Center

Smith, Christopher A.; And Others

1991-01-01

Authors describe some clinical features of glycoprotein biochemistry, including recognition, selected blood glycoproteins, glycated proteins, histochemistry, and cancer. The material presented has largely been taught to medical laboratory students; however, it can be used to teach premedical students and pure biochemistry students. Includes two…

Cyber Warfare: China’s Strategy to Dominate in Cyber Space

DTIC Science & Technology

2011-06-10

CYBER WARFARE : CHINA‘S STRATEGY TO DOMINATE IN CYBER SPACE A thesis presented to the Faculty of the U.S. Army Command and...warfare supports the use of cyber warfare in future conflict. The IW militia unit organization provides each Chinese military region commander with...China, Strategy, Cyber Warfare , Cyber Space, Information Warfare, Electronic Warfare 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18

Strategic Impact of Cyber Warfare Rules for the United States

DTIC Science & Technology

2010-03-01

Despite the growing complexities of cyberspace and the significant strategic challenge cyber warfare poses on the United States’ vital interests few...specific rules for cyber warfare exist. The United States should seek to develop and maintain cyber warfare rules in order to establish...exemplify the need for multilaterally prepared cyber warfare rules that will reduce the negative influence cyber warfare presently has on the United States’ national interests.

Initial Report of the Deans Cyber Warfare Ad Hoc Committee

DTIC Science & Technology

2011-12-22

in a cyber warfare environment. Among the more notable recent developments have been the establishment of a new Cyber Warfare Command (USCYBERCOM) at...information-warfare-centric organization. Clearly, future Naval Academy graduates will be expected to know more about cyber warfare than those we have...graduated in the past. The Academic Dean and Provost tasked an ad hoc committeethe Cyber Warfare ad hoc Committeeto examine how USNA can best ensure that

The Theory of Unconventional Warfare: Win, Lose, and Draw

DTIC Science & Technology

2008-12-01

UNCONVENTIONAL WARFARE MODEL ...................................12 1. Planning Phase...Superiority over Time........................................................................11  Figure 3.  Unconventional Warfare Model ...superiority through the six principles of UW illustrated below in the UW model . . B. THE UNCONVENTIONAL WARFARE MODEL Figure 3. Unconventional

Employing U.S. Information Operations Against Hybrid Warfare Threats

DTIC Science & Technology

2013-03-01

Article 51.24 Cyber warfare is unique in that vulnerabilities that a network target may have could be discovered by software developers who then... cyber warfare rather than physical combat, a future subject to air strikes or ground-forces raids would likely be a powerful deterrent. Some in the U.S...Manwaring, The Complexity of Modern Asymmetric Warfare, (Norman, OK: Univ. of Oklahoma Press, 2012), 126-129. 23 Arie J. Schaap, “ Cyber Warfare Operations

RFID as a Tool in Cyber Warfare

DTIC Science & Technology

2010-11-01

RTO-MP-IST-091 P4 - 1 RFID as a Tool in Cyber Warfare Mikko Kiviharju P.O.Box 10 FIN-11311 Riihimaki FINLAND mikko.kiviharju@mil.fi...auditing existing systems and planning new establishments. 1 INTRODUCTION Cyber warfare , especially computer network operations (CNO) have a deep...SUBTITLE RFID as a Tool in Cyber Warfare 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK

The Impacts of Modern Warfare on Freshwater Ecosystems

NASA Astrophysics Data System (ADS)

Francis, Robert A.

2011-11-01

There is increasing recognition and concern regarding the impacts of modern industrial warfare on the environment. Freshwater ecosystems are perhaps the most vulnerable to warfare-related impacts, which is of concern given that they provide so many essential environmental resources and services to society. Despite this, there has been little work to establish and quantify the types of impacts (both negative and positive) that warfare may have on such systems. This paper firstly highlights why rivers and lakes may be susceptible to warfare-related impacts, before synthesizing the available literature to explore the following main themes: intensification of wartime resource acquisition, use of water as an offensive or defensive weapon, direct and indirect effects of explosive ordnance, increased pollution, introduction of invasive alien species, and positive ecological impacts. This is then followed by a discussion of the implications of such impacts in relation to future warfare, including a consideration of the efficacy of existing legal instruments to protect the environment during conflict, and the trend for war to become more localized and `informal', and therefore less regulated. Finally, the paper identifies key research foci for understanding and mitigating the effects of warfare on freshwater ecosystems.

Chemical Warfare: Many Unanswered Questions.

DTIC Science & Technology

1983-04-29

of Defense DSB Defense Science Board GAO U.S. General Accounting Office IDA Institute for Defense Analyses JCS Joint Chiefs of Staff SIPRI Stockholm...Defense Science Board in 1980, DOD specifically asked it to review intelligence data on chemical warfare, and DSB’s 1981 report accordingly presents its...Defense Science Board report suggests, however, that its com- - ments are based on a composite of intelligence information on Soviet chemical warfare

Examining U.S. Irregular Warfare Doctrine

DTIC Science & Technology

2008-06-01

48 Future Theories ...Questions, and Hypotheses The classic warfare theories (i.e. Sun Tzu, Clausewitz, and so forth) directly apply to this research since they form the...Tzu, their theories on the conduct of warfare, and its close tie to politics, form the basis for examining the content of the manuals. The Marine

Department of Defenses Enhanced Requirement for Offensive Cyber Warfare Operations

DTIC Science & Technology

2010-04-01

The Department of Defense (DoD) needs to further develop its offensive cyber warfare capabilities at all levels. In an asymmetric environment...battlefields. If the DoD does not prosecute offensive cyber warfare tactics then the DoD has effectively allowed a significant advantage to be given...offensive cyber warfare operations, These states utilize their cyber warfare capabilities to support their national, operational and strategic

Beyond Mission Command: Maneuver Warfare for Cyber Command and Control

DTIC Science & Technology

2015-05-18

operation in an A2AD environment. 15. SUBJECT TERMS command and control; maneuver warfare; cyberspace; cyberspace operations; cyber warfare , mission...Some Principles of Cyber Warfare (NWC 2160) (U.S. Naval War College, Joint Military Operations Department, Newport, RI: U.S. Naval War College...research/ innovationleadership.pdf. Crowell, Richard M. Some Principles of Cyber Warfare (NWC 2160). U.S. Naval War College, Joint Military Operations

Maneuver Warfare revisited: a plea for balance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hamilton, M,R.

1986-04-01

This paper is a plea for balance in the current pursuit of understanding of the concept and the teaching of Maneuver Warfare. It specifically addresses the need for a more-complete analysis of some of the more-common historical examples commonly offered as examples of the supremecy of Maneuver Warfare. The paper in no way disagrees with the desirability of conducting the kinds of operations associated with the ill-defined concepts offered by advocates of Maneuver Warfare but suggests that the desirable results of historical battles may be too readily ascribed to the dynamic, offensive actions of the victorious side. Secondly, the papermore » points out the lack of utility and applicability of some common buzzwords being used in today's Army. Specifically assailed is the concept of turning within a decision cycle. The paper describes the reasons that this commonly used phrase has little applicability to ground warfare. Finally, the paper mentions the tendency for the Maneuver Warfare camp to cloud discussion of doctrine in a kind of intellectualism and elitism that has no use in forming the necessary consensus demanded by doctrine.« less

The role of rewards in motivating participation in simple warfare.

PubMed

Glowacki, Luke; Wrangham, Richard W

2013-12-01

In the absence of explicit punitive sanctions, why do individuals voluntarily participate in intergroup warfare when doing so incurs a mortality risk? Here we consider the motivation of individuals for participating in warfare. We hypothesize that in addition to other considerations, individuals are incentivized by the possibility of rewards. We test a prediction of this "cultural rewards war-risk hypothesis" with ethnographic literature on warfare in small-scale societies. We find that a greater number of benefits from warfare is associated with a higher rate of death from conflict. This provides preliminary support for the relationship between rewards and participation in warfare.

Beyond-the-Box Thinking on Future War: The Art and Science of Unrestricted Warfare

DTIC Science & Technology

2009-04-01

Studies Institute, US Army War College, 2008. Mattis , James N., and Frank Hoffman. “Future Warfare: The Rise of Hybrid Warfare.” Proceedings...nanotechnologies will augment the current bio -chemical capabilities, moving the battlefield into a microscopic arena. As seen before, the traditional American way...Military Trans-military Non-military Atomic Warfare Diplomatic Warfare Financial Warfare Conventional Warfare Network Warfare Trade Warfare Bio

Nodes and Codes: The Reality of Cyber Warfare

DTIC Science & Technology

2012-05-17

Nodes and Codes explores the reality of cyber warfare through the story of Stuxnet, a string of weaponized code that reached through a domain...nodes. Stuxnet served as a proof-of-concept for cyber weapons and provided a comparative laboratory to study the reality of cyber warfare from the...military powers most often associated with advanced, offensive cyber attack capabilities. The reality of cyber warfare holds significant operational

Smart Climatology Applications for Undersea Warfare

DTIC Science & Technology

2008-09-01

Comparisons of these climatologies with existing Navy climatologies based on the Generalized Digital Environmental Model ( GDEM ) reveal differences in sonic...undersea warfare. 15. NUMBER OF PAGES 117 14. SUBJECT TERMS antisubmarine warfare, climate variations, climatology, GDEM , ocean, re...climatologies based on the Generalized Digital Environmental Model ( GDEM ) to our smart ocean climatologies reveal a number of differences. The

Cyber Warfare: A Need for Beyond Goldwater-Nichols

DTIC Science & Technology

2011-05-13

of Military Studies Research Paper September 2010- May 2011 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Cyber Warfare : "A Need for Beyond Goldwater...22134-5068 MASTER OF MlLIT AR Y STUDJES Cyber Warfare : "A Need for Beyond Goldwater Nichols" SlffiMITTED IN PARTIAL FULFitLMENT OF THE...DOCUMENT IS PERMITTED PROVIDED PROPER ACKNOWLEDGEMENT IS MADE.· l . ii EXECUTIVE SUMMARY Title: Cyber Warfare : "A Need for Beyond Goldwater Nichols

Adapting Unconventional Warfare Doctrine to Cyberspace Operations: An Examination of Hacktivist Based Insurgencies

DTIC Science & Technology

2015-06-12

Unconventional Warfare, Cyberspace Operations, Cyber Warfare , Hacktivism, China, Russia, Georgia, Estonia, Umbrella Revolution, UW, Cyber, Guerilla, Hacktivist...6 Cyber Warfare ............................................................................................................. 7...Internet, and cyber warfare , the nature of the human element in cyberspace exhibits only a scientific advancement in the evolution of warfare, not a

Anxiety, depression, and posttraumatic stress in Iranian survivors of chemical warfare.

PubMed

Hashemian, Farnoosh; Khoshnood, Kaveh; Desai, Mayur M; Falahati, Farahnaz; Kasl, Stanislav; Southwick, Steven

2006-08-02

In the 1980-1988 Iran-Iraq War, extensive use of chemical weapons resulted in high rates of morbidity and mortality. While much is known about the physical consequences of chemical warfare, there is a paucity of information about the long-term effects of chemical attacks on mental health. To assess the long-term psychological impact of chemical warfare on a civilian population. Cross-sectional randomized survey conducted in July 2004 of 153 civilians in 3 towns exposed to warfare in northwestern Iran: Oshnaviyeh (low-intensity conventional warfare), Rabat (high-intensity conventional warfare), and Sardasht (both high-intensity conventional warfare and chemical weapons). Full or partial posttraumatic stress disorder (PTSD) diagnosis, anxiety symptoms, and depressive symptoms were assessed using Farsi versions of the Clinician-Administered PTSD Scale, Hamilton Scale for Anxiety, and Beck Depression Inventory, respectively. Overall participation rate was 93%. Respondents had a mean age of 45 years and were all of Kurdish ethnicity. Among individuals exposed to both high-intensity warfare and chemical weapons, prevalence rates for lifetime PTSD, current PTSD, major anxiety symptoms, and severe depressive symptoms were 59%, 33%, 65%, and 41%, respectively. Among the low-intensity warfare group, the corresponding rates were 8%, 2%, 18%, and 6%, respectively, while intermediate rates were found among those exposed to high-intensity warfare but not to chemical weapons (31%, 8%, 26%, and 12%, respectively). Compared with individuals exposed to low-intensity warfare, those exposed to both high-intensity warfare and chemical weapons were at higher risk for lifetime PTSD (odds ratio [OR], 18.6; 95% confidence interval [CI], 5.8-59.4), current PTSD (OR, 27.4; 95% CI, 3.4-218.2), increased anxiety symptoms (OR, 14.6; 95% CI, 6.0-35.6), and increased depressive symptoms (OR, 7.2; 95% CI, 3.3-15.9). Exposure to high-intensity warfare but not to chemical weapons was also

Chemical warfare, past and future. Study project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tzihor, A.

1992-05-15

World War I was arena for the first use of chemical warfare. The enormous tactical success brought about by this first time use of chemical weapons caused the continued development of more sophisticated tactics and weapons in this category of unconventional warfare. This phenomenon has carried through to today. However, at present, because of technological developments, the global economic situation, and political factors, coupled with the inability of the western world to control the proliferation of chemical weapons, a situation weapon of mass destruction. Recent use by Iraq against Kurdish civilian indicates that chemical warfare is no longer limited tomore » the battlefield. The western nations have a need to understand the risk. This paper conducts an analysis of past lessons and the factors which will affect the use of chemical warfare in the future. From this analysis, the paper reaches conclusions concerning the significant threat chemical weapons pose for the entire world in the not too distant future.« less

New Edition of Chinese Biochemistry Textbook.

ERIC Educational Resources Information Center

Jian-Chuan, Ma

1988-01-01

Discusses the four previous editions of the biochemistry medical textbooks called the "Nationwide Unified Textbooks." Notes the new (1989) edition is much smaller, is organized differently, has new material, has a reorganized Dynamic Biochemistry core, and shows great importance to clinical biochemistry. (MVL)

Environmental Warfare

ERIC Educational Resources Information Center

Barnaby, Frank

1976-01-01

Recent discussions at the Conference of the Committee on Disarmament have focused on the use of artificial changes in the environment as a method of warfare. A far more urgent task is development of a specific ban on already available techniques of environmental damage and a general and complete disarmament. (BT)

What Good Are Warfare Models?

DTIC Science & Technology

1981-05-01

PROFESSIONAL PAPER 306 / May 1981 WHAT GOOD ARE WARFARE MODELS? Thomas E. Anger DTICS E LECTE ,JUN 2198 1 j CENTER FOR NAVAL ANALYSES 81 6 19 025 V...WHAT GOOD ARE WARFARE MODELS? Thomas E. /Anger J Accession For !ETIS GRA&I DTIC TAB thonnounceldŕ 5 By-C Availability Codes iAva il aand/or Di1st...least flows from a life-or-death incenLive to make good guesses when choosing weapons, forces, or strategies. It is not surprising, however, that

Small Ships Revival: From Cold War Anti-Invasion and Guerrilla Warfare Tactics to Highly Capable Force Multiplier in Littoral and Expeditionary Warfare

DTIC Science & Technology

2010-05-03

this gap might be filled. It will focus on the surface warfare aspect of sea control, though it touches on antiair warfare, mine warfare and...Sea As the flotilla acquired battle power […] the vital, most difficult, and most absorbing problem has become not how to increase the power of a...proving that their performance is absolutely necessary to these operations. Com Fr Amphib TG of the NATO Reaction Force-8 after Exercise Brilliant Midas

Development of JSDF Cyber Warfare Defense Critical Capability

DTIC Science & Technology

2010-03-01

attack identification capability is essential for a nation to defend her vital infrastructures against offensive cyber warfare . Although the necessity of...cyber-attack identification capability is quite clear, the Japans preparation against cyber warfare is quite limited.

[Research activity in clinical biochemistry].

PubMed

Jørgensen, Henrik L; Larsen, Birger; Ingwersen, Peter; Rehfeld, Jens F

2008-09-01

Quantitative bibliometric measurements of research activity are frequently used, e.g. for evaluating applicants for academic positions. The purpose of this investigation is to assess research activity within the medical speciality of Clinical Biochemistry by comparing it with a matched control group from other medical specialities in Denmark. A list of all physicians registered in Denmark (23,127 persons) was drawn from the database "Laeger.dk". Of these, 5,202 were generalists (not included) while 11,691 were from other specialities. Of the 126 specialists from Clinical Biochemistry, 57 fulfilled the inclusion criteria. Each of these 57 was matched according to medical title with two randomly chosen specialists from other specialities, totaling 114. Using Medline and the Web of Science, the number of publications and the number of citations were then ascertained. 25% of the 11,691 specialists held a PhD degree or doctoral degree, DMSci, (Clinical Biochemistry: 61%). The 171 specialists included in the study had 9,823 papers in Medline and 10,140 papers in the Web of Science. The number of Medline papers per specialist was 71 for Clinical Biochemistry compared to 51 for the control group. The number of citations per specialist was 1,844 for Clinical Biochemistry compared to 816 for the control group. The top ten H-indices (of which 8 were in Clinical Biochemistry) ranged from 30 to 69. Both the number of papers and the number of citations were higher for Clinical Biochemistry than for the control group. The difference was most pronounced among professors.

Biochemistry

USDA-ARS?s Scientific Manuscript database

Part of the framework for effective control or management of cyst nematodes depends upon the detailed understanding of their biology. This chapter summarizes fundamental knowledge and recent discoveries about the biochemistry of cyst nematodes, particularly areas related to lipids, carbohydrates and...

Software Acquisition in the Age of Cyber Warfare

DTIC Science & Technology

2011-05-01

s c h o o l o f S Y S T E M S a n d L O G I S T I C S education service research Software Acquisition in the Age of Cyber Warfare Maj...DATE MAY 2011 2. REPORT TYPE 3. DATES COVERED 00-00-2011 to 00-00-2011 4. TITLE AND SUBTITLE Software Acquisition in the Age of Cyber Warfare 5a...AFIT Cyber 200/300 Courses Cyber Warfare IDE Program 34 Special Emphasis On… Enterprise Integration (Active Directory, PKI) Security

Warfare or partnership: which way for health care?

PubMed

MacStravic, R S

1990-01-01

There are many voices urging health care organizations to adopt aggressive competitive warfare, but a careful look at the dynamics affecting health care suggests that partnership may be at least as promising a strategy as warfare to promote mission and survival.

The Fate of Chemical Warfare Agents in the Environment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Talmage, Sylvia Smith; Munro, Nancy B; Watson, Annetta Paule

2007-01-01

Chemical Warfare Agents, Second Edition has been totally revised since the successful first edition and expanded to about three times the length, with many new chapters and much more in-depth consideration of all the topics. The chapters have been written by distinguished international experts in various aspects of chemical warfare agents and edited by an experienced team to produce a clear review of the field. The book now contains a wealth of material on the mechanisms of action of the major chemical warfare agents, including the nerve agent cyclosarin, formally considered to be of secondary importance, as well as ricinmore » and abrin. Chemical Warfare Agents, Second Edition discusses the physico-chemical properties of chemical warfare agents, their dispersion and fate in the environment, their toxicology and management of their effects on humans, decontamination and protective equipment. New chapters cover the experience gained after the use of sarin to attack travelers on the Tokyo subway and how to deal with the outcome of the deployment of riot control agents such as CS gas. This book provides a comprehensive review of chemical warfare agents, assessing all available evidence regarding the medical, technical and legal aspects of their use. It is an invaluable reference work for physicians, public health planners, regulators and any other professionals involved in this field.« less

Remote sensing of chemical warfare agent by CO2 -lidar

NASA Astrophysics Data System (ADS)

Geiko, Pavel P.; Smirnov, Sergey S.

2014-11-01

The possibilities of remote sensing of chemical warfare agent by differential absorption method were analyzed. The CO2 - laser emission lines suitable for sounding of chemical warfare agent with provision for disturbing absorptions by water vapor were choose. The detection range of chemical warfare agents was estimated for a lidar based on CO2 - laser The other factors influencing upon echolocation range were analyzed.

The Biochemistry Tetrahedron and the Development of the Taxonomy of Biochemistry External Representations (TOBER)

ERIC Educational Resources Information Center

Towns, Marcy H.; Raker, Jeffrey R.; Becker, Nicole; Harle, Marissa; Sutcliffe, Jonathan

2012-01-01

Visual literacy, the ability to interpret and create external representations (ERs), is essential to success in biochemistry. Studies have been conducted that describe students' abilities to use and interpret specific types of ERs. However, a framework for describing ERs derived through a naturalistic inquiry of biochemistry classrooms has not…

Surface Warfare Officers Initial Training For Future Success

DTIC Science & Technology

2018-03-01

updating and creating learning modules and Surface Warfare Officer School (SWOS) staffing as well as weaknesses in the methodologies used for...and Surface Warfare Officer School (SWOS) staffing as well as weaknesses in the methodologies used for training. We conclude that the Basic Division... METHODOLOGY ....................................................................................9 1. Staff Interviews

Studies of biochemistry and clinical biochemistry. Studies at sample medical schools in 13 EU countries regarding biochemistry and clinical biochemistry teaching.

PubMed

Stern, Petr; Sebesta, Ivan; Trnkova, Bohuslava; Zima, Tomas

2008-07-01

The study summarizes the results obtained during personal visits to 53 medical schools in the 13 original EU countries during 2004--2006. Data from the Czech Republic is shown for comparison. The possibilities of acquiring information from the websites of the medical schools in the local language and English are assessed. The admission process to medical schools and the organization of studies of medicine, dentistry, and non-medical healthcare fields are briefly characterized. Significant attention is paid to the forms of education in biochemistry and clinical (bio)chemistry in the medical study field. The position of these subjects in the studies of dentistry and non-medical healthcare fields is also noted. In addition, the course of subject exams is described. The methods of funding and postgraduate studies at the medical schools are also briefly addressed.

A Better State of War: Surmounting the Ethical Cliff in Cyber Warfare

DTIC Science & Technology

2014-06-01

This study analyzes the emergent field of cyber warfare through the lens of commonly-accepted tenets of ethical warfare. By comparing the...foundational understanding of concepts that determine the justice of wars (jus ad bellum) and justice in war (jus en bello) with the capabilities cyber warfare offers...analyzing how cyber warfare affects each of the core concepts introduced above. The fourth chapter presents a case study that tests the theoretical

The Future of Warfare and Impact of Space Operations

DTIC Science & Technology

2011-01-01

cyber warfare is occurring as a preferred method of conflict between large players on the global stage. Smaller players also have reasons to avoid conventional warfare and remain hidden. In Iraq and Afghanistan, those who fight against us attempt to remain hidden. The individual who places an improvised explosive device (IED) attempts to engage us without exposure or identification. Those who aid the individual emplacing an IED do so with hidden networks of support. The IED is an anonymous weapon. Both cyber warfare and insurgent use of IEDs depend

Education in Medical Biochemistry in Serbia

PubMed Central

2010-01-01

Medical biochemistry is the usual name for clinical biochemistry or clinical chemistry in Serbia. Medical biochemistry laboratories and medical biochemists as a profession are part of Health Care System and are regulated through: the Health Care Law and rules issued by the Chamber of Medical Biochemists of Serbia. The first continuous and organized education for Medical Biochemists in Serbia dates from 1945, when Department of Medical Biochemistry was established at Pharmaceutical Faculty in Belgrade. In 1987 at the same Faculty a five years undergraduate branch was established, educating Medical Biochemists under a special program. Since 2006 the new five year undergraduate (according to Bologna Declaration) and postgraduate program of four-year specialization according to EC4 European Syllabus for Post-Graduate Training in Clinical Chemistry and Laboratory Medicine has been established. The Ministry of Education and Ministry of Public Health accredits the programs. There are four requirements for practicing medical biochemistry in the Health Care System: University Diploma of the Faculty of Pharmacy (Medical Biochemistry), successful completion of the profession exam at the Ministry of Health after completion of one additional year of obligatory practical training in medical laboratories, membership in the Serbian Chamber of Medical Biochemists and licence for skilled work issued by Serbian Chamber of Medical Biochemists. PMID:27683360

Education in Medical Biochemistry in Serbia.

PubMed

Majkic-Sing, Nada

2010-06-01

Medical biochemistry is the usual name for clinical biochemistry or clinical chemistry in Serbia. Medical biochemistry laboratories and medical biochemists as a profession are part of Health Care System and are regulated through: the Health Care Law and rules issued by the Chamber of Medical Biochemists of Serbia. The first continuous and organized education for Medical Biochemists in Serbia dates from 1945, when Department of Medical Biochemistry was established at Pharmaceutical Faculty in Belgrade. In 1987 at the same Faculty a five years undergraduate branch was established, educating Medical Biochemists under a special program. Since 2006 the new five year undergraduate (according to Bologna Declaration) and postgraduate program of four-year specialization according to EC4 European Syllabus for Post-Graduate Training in Clinical Chemistry and Laboratory Medicine has been established. The Ministry of Education and Ministry of Public Health accredits the programs. There are four requirements for practicing medical biochemistry in the Health Care System: University Diploma of the Faculty of Pharmacy (Medical Biochemistry), successful completion of the profession exam at the Ministry of Health after completion of one additional year of obligatory practical training in medical laboratories, membership in the Serbian Chamber of Medical Biochemists and licence for skilled work issued by Serbian Chamber of Medical Biochemists.

Biochemistry Textbooks for Effective Learning.

ERIC Educational Resources Information Center

Vella, F.

1992-01-01

Suggests that more attention be paid by biochemistry textbook authors to the breadth of contemporary learning strategies, given the fact that an increasing number of medical schools have adopted an integrated, self-paced, problem-based curriculum. Discusses the theoretical characteristics desirable in the ideal biochemistry textbook. (JJK)

Teaching biochemistry online at Oregon State University.

PubMed

Ahern, Kevin

2017-01-02

A strategy for growing online biochemistry courses is presented based on successes in ecampus at Oregon State University. Four free drawing cards were key to the effort-YouTube videos, iTunes U online free course content, an Open Educational Resource textbook-Biochemistry Free and Easy, and a fun set of educational songs known as the Metabolic Melodies. © 2016 by The International Union of Biochemistry and Molecular Biology, 45(1):25-30, 2017. © 2016 The International Union of Biochemistry and Molecular Biology.

History of the Chemical Warfare Service in World War II. Biological Warfare Research in the United States, Volume 2

DTIC Science & Technology

1947-11-01

of proteins and other substances of high molecular weight derived from bacteria, or from natural products with antibacterial activity Proteins and...WARFARE RESEARCH IS THE UNITED r STATES, is one of a series of historical monographs on the research and development activities of the Chemical...TSC Committee 16 War Research Service 13 A5C Committee •• 21 CWS Activities Under TSRS 22 Transfer of Biological Warfare Program to TTar

Developing a Hybrid Virtualization Platform Design for Cyber Warfare Training and Education

DTIC Science & Technology

2010-06-01

CYBER WARFARE TRAINING AND EDUCATION THESIS Kyle E. Stewart 2nd...Government. AFIT/GCE/ENG/10-06 DEVELOPING A HYBRID VIRTUALIZATION PLATFORM DESIGN FOR CYBER WARFARE TRAINING...APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED. AFIT/GCE/ENG/10-06 DEVELOPING A HYBRID VIRTUALIZATION PLATFORM DESIGN FOR CYBER WARFARE

At the Crossroads of Cyber Warfare: Signposts for the Royal Australian Air Force

DTIC Science & Technology

2011-06-01

At the Crossroads of Cyber Warfare : Signposts for the Royal Australian Air Force by Craig Stallard, Squadron leader, Royal...in the conduct of cyber warfare . The 2009 Defence White Paper provided some clarity by indentifying cyber warfare as critical to the maintenance...of national security, but left open the most important issue: should cyber warfare be a joint engagement or a service oriented fight? The RAAF

Searching for Alien Life Having Unearthly Biochemistry

NASA Technical Reports Server (NTRS)

Jones, Harry

2003-01-01

The search for alien life in the solar system should include exploring unearth-like environments for life having an unearthly biochemistry. We expect alien life to conform to the same basic chemical and ecological constraints as terrestrial life, since inorganic chemistry and the laws of ecosystems appear to be universal. Astrobiologists usually assume alien life will use familiar terrestrial biochemistry and therefore hope to find alien life by searching near water or by supplying hydrocarbons. The assumption that alien life is likely to be based on carbon and water is traditional and plausible. It justifies high priority for missions to search for alien life on Mars and Europa, but it unduly restricts the search for alien life. Terrestrial carbon-water biochemistry is not possible on most of the bodies of our solar system, but all alien life is not necessarily based on terrestrial biochemistry. If alien life has a separate origin from Earth life, and if can survive in an environment extremely different from Earth's, then alien life may have unearthly biochemistry. There may be other solvents than water that support alien life and other elements than carbon that form complex life enabling chain molecules. Rather than making the exploration-restricting assumption that all life requires carbon, water, and terrestrial biochemistry, we should make the exploration-friendly assumption that indigenous, environmentally adapted, alien life forms might flourish using unearthly biochemistry in many places in the solar system. Alien life might be found wherever there is free energy and a physical/chemical system capable of using that energy to build living structures. Alien life may be discovered by the detection of some general non-equilibrium chemistry rather than of terrestrial biochemistry. We should explore all the potential abodes of life in the solar system, including those where life based on terrestrial biochemistry can not exist.

Naval Warfare

DTIC Science & Technology

2010-03-01

Naval Doctrine Publication 1 Naval Warfare March 2010 Doctrine The only satisfactory method of ensuring unity of effort lies in due...LCDR Dudley W. Knox, USN “The Role of Doctrine in Naval Warfare” U.S. Naval Institute Proceedings, 1915 01 March 2010 FOREWORD United States (US...naval doctrine is the foundation upon which our tactics, techniques, and procedures are built. It articulates operational concepts that govern the

Nuclear, biological and chemical warfare. Part I: Medical aspects of nuclear warfare.

PubMed

Kasthuri, A S; Pradhan, A B; Dham, S K; Bhalla, I P; Paul, J S

1990-04-01

Casualties in earlier wars were due much more to diseases than to weapons. Mention has been made in history of the use of biological agents in warfare, to deny the enemy food and water and to cause disease. In the first world war chemical agents were used to cause mass casualties. Nuclear weapons were introduced in the second world war. Several countries are now involved in developing nuclear, biological and chemical weapon systems, for the mass annihilation of human beings, animals and plants, and to destroy the economy of their enemies. Recently, natural calamities and accidents in nuclear, chemical and biological laboratories and industries have caused mass instantaneous deaths in civilian population. The effects of future wars will not be restricted to uniformed persons. It is time that physicians become aware of the destructive potential of these weapons. Awareness, immediate protective measures and first aid will save a large number of persons. This series of articles will outline the medical aspects of nuclear, biological and chemical weapon systems in three parts. Part I will deal with the biological effects of a nuclear explosion. The short and long term effects due to blast, heat and associated radiation are highlighted. In Part II, the role of biological agents which cause commoner or new disease patterns is mentioned. Some of the accidents from biological warfare laboratories are a testimony to its potential deleterious effects. Part III deals with medical aspects of chemical warfare agents, which in view of their mass effects can overwhelm the existing medical resources, both civilian and military.(ABSTRACT TRUNCATED AT 250 WORDS)

Defending Our Satellites: The Need for Electronic Warfare Education and Training

DTIC Science & Technology

2015-12-01

intercept Allied bombers attacking at night.9 As a result of the electronic warfare advantage that systems like Window and Airborne Cigar be- stowed...74 | Air & Space Power Journal Defending Our Satellites The Need for Electronic Warfare Education and Training Lt Col E. Lincoln Bonner, USAF...expanding education and training in the use of electronic warfare to defend US satellites and improve their survivability. The following discussion

Biodegradation of Organophosphate Chemical Warfare Agents by Activated Sludge

DTIC Science & Technology

2012-03-01

Holmstedt, B. (1963). Structure- activity relationships of the organophosphorus anticholinesterase agents. In: Koelle, G.B. (ed.), Handbuch...BIODEGRADATION OF ORGANOPHOSPHATE CHEMICAL WARFARE AGENTS BY ACTIVATED SLUDGE Steven J. Schuldt...AFIT/GES/ENV/12-M04 BIODEGRADATION OF ORGANOPHOSPHATE CHEMICAL WARFARE AGENTS BY ACTIVATED SLUDGE THESIS Presented to the

[Scientific and practical activity of the Department of Muscle Biochemistry of the Palladin Institute of Biochemistry of NAS of Ukraine].

PubMed

Vynogradova, R P; Danilova, V M; Yurasova, S P

2017-01-01

The article focuses on scientific and practical activity of the Department of Muscle Biochemistry of the Palladin Institute of Biochemistry of NAS of Ukraine in the context of its foundation and development. Main findings and practical achievements in the area of muscle biochemistry are summarized and discussed.

75 FR 6642 - Notice of Proposed Information Collection; Naval Special Warfare Recruiting Directorate

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

... Information Collection; Naval Special Warfare Recruiting Directorate AGENCY: Department of the Navy, DoD. ACTION: Notice. SUMMARY: The Naval Special Warfare (NSW) Recruiting Directorate announces the submission... the proposal and associated collection instruments, write to the Director, Naval Special Warfare...

A Deeper Level of Network Intelligence: Combating Cyber Warfare

DTIC Science & Technology

2010-04-01

A Deeper Level of Network Intelligence: Combating Cyber Warfare This information is provided for your review only and is not for any distribution...A Deeper Level of Network Intelligence: Combating Cyber Warfare 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d

The Handicap Principle, Strategic Information Warfare and the Paradox of Asymmetry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ma, Zhanshan; Sheldon, Frederick T; Krings, Axel

2010-01-01

The term asymmetric threat (or warfare) often refers to tactics utilized by countries, terrorist groups, or individuals to carry out attacks on a superior opponent while trying to avoid direct confrontation. Information warfare is sometimes also referred to as a type of asymmetric warfare perhaps due to its asymmetry in terms of cost and efficacy. Obviously, there are differences and commonalities between two types of asymmetric warfare. One major difference lies in the goal to avoid confrontation and one commonality is the asymmetry. Regardless, the unique properties surrounding asymmetric warfare warrant a strategic-level study. Despite enormous studies conducted in themore » last decade, a consensus on the strategy a nation state should take to deal with asymmetric threat seems still intriguing. In this article, we try to shed some light on the issue from the handicap principle in the context of information warfare. The Handicap principle was first proposed by Zahavi (1975) to explain the honesty or reliability of animal communication signals. He argued that in a signaling system such as one used in mate selection, a superior male is able to signal with a highly developed "handicap" to demonstrate its quality, and the handicap serves "as a kind of (quality) test imposed on the individual" (Zahavi 1975, Searcy and Nowicki 2005). The underlying thread that inspires us for the attempt to establish a connection between the two apparently unrelated areas is the observation that competition, communication and cooperation (3C), which are three fundamental processes in nature and against which natural selection optimize living things, may also make sense in human society. Furthermore, any communication networks, whether it is biological networks (such as animal communication networks) or computer networks (such as the Internet) must be reasonably reliable (honest in the case of animal signaling) to fulfill its missions for transmitting and receiving messages. The

Biochemistry for dietetic students: course content and format.

PubMed

Sirota, L H

1984-12-01

This article presents the results of a survey of the 251 undergraduate dietetic programs for course content and level of the biochemistry course most frequently used to satisfy competencies in biochemistry under Plan IV of the ADA in 1979-80. It showed that a common core of information was stressed by all biochemistry instructors, but there was great variability in content and level of material covered and the textbook chosen, depending on whether the biochemistry course was offered to dietetic majors only, in classes with other nonchemistry majors, or in classes with chemistry majors. Variability was also seen in the time allotted for biochemistry--39 to 280 hours (total lecture and required laboratory hours); laboratory requirements--only 71%; and departmental affiliation of the instructor--17 different departments, primarily of chemistry (80%), biology (8%), and home economics (4%). Topics given greatest emphasis were descriptive ones, such as definitions, simple structures, and reactions of intermediary metabolism in general terms. Topics given least emphasis were those involving mechanistic and quantitative biochemistry, such as respiratory quotient (RQ), enzyme kinetics, calculations of energy from fat and carbohydrates, and specific structures of vitamins, ketones, and metabolic intermediates. The lack of communication between biochemistry and nutrition instructors and the great differences in the preparation of dietetic majors in biochemistry are sources of concern.

Identification of Threshold Concepts for Biochemistry

PubMed Central

Green, David; Lewis, Jennifer E.; Lin, Sara; Minderhout, Vicky

2014-01-01

Threshold concepts (TCs) are concepts that, when mastered, represent a transformed understanding of a discipline without which the learner cannot progress. We have undertaken a process involving more than 75 faculty members and 50 undergraduate students to identify a working list of TCs for biochemistry. The process of identifying TCs for biochemistry was modeled on extensive work related to TCs across a range of disciplines and included faculty workshops and student interviews. Using an iterative process, we prioritized five concepts on which to focus future development of instructional materials. Broadly defined, the concepts are steady state, biochemical pathway dynamics and regulation, the physical basis of interactions, thermodynamics of macromolecular structure formation, and free energy. The working list presented here is not intended to be exhaustive, but rather is meant to identify a subset of TCs for biochemistry for which instructional and assessment tools for undergraduate biochemistry will be developed. PMID:25185234

Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and Hardware Development

DTIC Science & Technology

2016-09-01

ARL-TN-0779 ● SEP 2016 US Army Research Laboratory Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and...Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and Hardware Development by Neal Tesny Sensors and Electron Devices Directorate...TITLE AND SUBTITLE Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and Hardware Development 5a. CONTRACT NUMBER 5b

Homeland Biological Warfare Consequence Management: Capabilities and Needs Assessment

DTIC Science & Technology

2001-04-01

AU/ACSC/105/2001-04 AIR COMMAND AND STAFF COLLEGE AIR UNIVERSITY HOMELAND BIOLOGICAL WARFARE CONSEQUENCE MANAGEMENT: CAPABILITIES AND NEEDS...Dates Covered (from... to) - Title and Subtitle Homeland biological Warfare Consequence Management: Capabilities and Needs Assessment Contract...FEMA, DoJ, DoD, HHS, etc.) make a comprehensive, organized solution to the problem difficult. Focusing on the consequence management functions

Simulating cyber warfare and cyber defenses: information value considerations

NASA Astrophysics Data System (ADS)

Stytz, Martin R.; Banks, Sheila B.

2011-06-01

Simulating cyber warfare is critical to the preparation of decision-makers for the challenges posed by cyber attacks. Simulation is the only means we have to prepare decision-makers for the inevitable cyber attacks upon the information they will need for decision-making and to develop cyber warfare strategies and tactics. Currently, there is no theory regarding the strategies that should be used to achieve objectives in offensive or defensive cyber warfare, and cyber warfare occurs too rarely to use real-world experience to develop effective strategies. To simulate cyber warfare by affecting the information used for decision-making, we modify the information content of the rings that are compromised during in a decision-making context. The number of rings affected and value of the information that is altered (i.e., the closeness of the ring to the center) is determined by the expertise of the decision-maker and the learning outcome(s) for the simulation exercise. We determine which information rings are compromised using the probability that the simulated cyber defenses that protect each ring can be compromised. These probabilities are based upon prior cyber attack activity in the simulation exercise as well as similar real-world cyber attacks. To determine which information in a compromised "ring" to alter, the simulation environment maintains a record of the cyber attacks that have succeeded in the simulation environment as well as the decision-making context. These two pieces of information are used to compute an estimate of the likelihood that the cyber attack can alter, destroy, or falsify each piece of information in a compromised ring. The unpredictability of information alteration in our approach adds greater realism to the cyber event. This paper suggests a new technique that can be used for cyber warfare simulation, the ring approach for modeling context-dependent information value, and our means for considering information value when assigning cyber

Television Medical Dramas as Case Studies in Biochemistry

ERIC Educational Resources Information Center

Millard, Julie T.

2009-01-01

Several case studies from popular television medical dramas are described for use in an undergraduate biochemistry course. These cases, which illustrate fundamental principles of biochemistry, are used as the basis for problems that can be discussed further in small groups. Medical cases provide an interesting context for biochemistry with video…

The Characterization and Measurement of Cyber Warfare, Spring 2008 - Project 08-01

DTIC Science & Technology

2008-05-01

Global Innovation and Strategy Center The Characterization and Measurement of Cyber Warfare Spring 2008 – Project 08-01 May 2008...and Measurement of Cyber Warfare N/A N/A N/A 08-01Dobitz, Kyle Haas, Brad Holtje, Michael Jokerst, Amanda Ochsner, Geoff Silva, Stephanie...research team as critical for purposes of cyber act characterization: Motivation, Intent, Target, Effects, and Actors. cyberspace, cyber warfare , targets

Femoral vessel injuries in modern warfare since Vietnam.

PubMed

Pearl, Jonathan P; McNally, Michael P; Perdue, Philip W

2003-09-01

The incidence of lower extremity injuries is high in modern warfare; however the mortality rate from these injuries is low. Despite the overall low mortality of lower extremity injuries, many deaths in modern conflicts are due to femoral vessel injury. The modern warfare literature was reviewed. In Somalia, 1 of the 14 reported deaths was due to a laceration of the superficial femoral artery. In the Persian Gulf, three deaths were reported in an Army field hospital, one resulted from uncontrolled hemorrhage from a profunda femoris artery wound and two others resulted from traumatic amputations with consequent major arterial injury. Despite the advances in modern body armor, the groin is left unprotected. A strategy to help minimize U.S. casualties in modern warfare may be a method of field hemostasis specifically designed for femoral vessel injury.

The Physics of Warfare

NASA Astrophysics Data System (ADS)

Giordano, Gerardo

2015-03-01

Recently, I was tasked with the creation and execution of a new themed general education physics class called The Physics of Warfare. In the past, I had used the theme of a class, such as the physics of sports medicine, as a way to create homework and in-class activities, generate discussions, and provide an application to demonstrate that physics isn't always abstract. It is true that the examples and applications in this warfare class practically wrote themselves, but I wanted more for my students. I wanted them to embrace the iterative nature of scientific understanding. I wanted them to yearn for the breakthroughs that lead to paradigm shifts. I wanted them to demand experimental verification of each novel idea. This paper discusses the formation and implementation of a conceptual physics course, full of in-class demonstrations and solidly rooted in the context of humankind's ever-evolving methods of waging war.

Information Warfare and the Principles of War.

DTIC Science & Technology

1997-02-07

information dominance , control of ’cyberspace’ or the ’Infosphere’ and Information Warfare. Some argue that Information Warfare (IW) is just a repackaging of old concepts and current practices, while others contend it is the next Revolution in Military Affairs (RMA). The question that needs to be addressed is; can IW achieve strategic and operational military objectives on its on merit? A way to answer this questions is to analyze IW against our current doctrine. Using the principles of war as a framework, does IW fit (or can it be employed) in the

Design and implementation of intelligent electronic warfare decision making algorithm

NASA Astrophysics Data System (ADS)

Peng, Hsin-Hsien; Chen, Chang-Kuo; Hsueh, Chi-Shun

2017-05-01

Electromagnetic signals and the requirements of timely response have been a rapid growth in modern electronic warfare. Although jammers are limited resources, it is possible to achieve the best electronic warfare efficiency by tactical decisions. This paper proposes the intelligent electronic warfare decision support system. In this work, we develop a novel hybrid algorithm, Digital Pheromone Particle Swarm Optimization, based on Particle Swarm Optimization (PSO), Ant Colony Optimization (ACO) and Shuffled Frog Leaping Algorithm (SFLA). We use PSO to solve the problem and combine the concept of pheromones in ACO to accumulate more useful information in spatial solving process and speed up finding the optimal solution. The proposed algorithm finds the optimal solution in reasonable computation time by using the method of matrix conversion in SFLA. The results indicated that jammer allocation was more effective. The system based on the hybrid algorithm provides electronic warfare commanders with critical information to assist commanders in effectively managing the complex electromagnetic battlefield.

Biomaterials for mediation of chemical and biological warfare agents.

PubMed

Russell, Alan J; Berberich, Jason A; Drevon, Geraldine F; Koepsel, Richard R

2003-01-01

Recent events have emphasized the threat from chemical and biological warfare agents. Within the efforts to counter this threat, the biocatalytic destruction and sensing of chemical and biological weapons has become an important area of focus. The specificity and high catalytic rates of biological catalysts make them appropriate for decommissioning nerve agent stockpiles, counteracting nerve agent attacks, and remediation of organophosphate spills. A number of materials have been prepared containing enzymes for the destruction of and protection against organophosphate nerve agents and biological warfare agents. This review discusses the major chemical and biological warfare agents, decontamination methods, and biomaterials that have potential for the preparation of decontamination wipes, gas filters, column packings, protective wear, and self-decontaminating paints and coatings.

Chemical warfare agents. Classes and targets.

PubMed

Schwenk, Michael

2018-09-01

Synthetic toxic chemicals (toxicants) and biological poisons (toxins) have been developed as chemical warfare agents in the last century. At the time of their initial consideration as chemical weapon, only restricted knowledge existed about their mechanisms of action. There exist two different types of acute toxic action: nonspecific cytotoxic mechanisms with multiple chemo-biological interactions versus specific mechanisms that tend to have just a single or a few target biomolecules. TRPV1- and TRPA-receptors are often involved as chemosensors that induce neurogenic inflammation. The present work briefly surveys classes and toxicologically relevant features of chemical warfare agents and describes mechanisms of toxic action. Copyright © 2017 Elsevier B.V. All rights reserved.

Teaching of biochemistry in medical school: A well-trodden pathway?

PubMed

Mathews, Michael B; Stagnaro-Green, Alex

2008-11-01

Biochemistry and molecular biology occupy a unique place in the medical school curriculum. They are frequently studied prior to medical school and are fundamental to the teaching of biomedical sciences in undergraduate medical education. These two circumstances, and the trend toward increased integration among the disciplines, have led to reconsideration of biochemistry instruction in many medical schools. We conducted a survey to explore the evolving trends in biochemistry education. A broad diversity was evident in parameters including course content, faculty, governance, prerequisites, and teaching methods. Notably, sharp differences were apparent between freestanding biochemistry courses and those in which biochemistry is integrated with other subjects. Furthermore, the data imply a likely trend toward increased integration of biochemistry with other disciplines in the medical school curriculum. Copyright © 2008 International Union of Biochemistry and Molecular Biology, Inc.

Counter-Unmanned Aerial Vehicle Warfare: Kill Authorizations for the Carrier Strike Group

DTIC Science & Technology

2016-06-10

COUNTER-UNMANNED AERIAL VEHICLE WARFARE: KILL AUTHORIZATIONS FOR THE CARRIER STRIKE GROUP A thesis presented to the Faculty...the Carrier Strike Group 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) LCDR Joshua C. Mattingly, U.S...including armed UAVs in an offensive role, but counter- UAV warfare is a new warfare area within the larger realm of air defense. Small Group 1 and 2

Genesis of "Biochemistry: A Problems Approach"

ERIC Educational Resources Information Center

Wood, William B.

2002-01-01

When the author began teaching as a young assistant professor at Caltech in 1966, his assignment was to take over the undergraduate biochemistry course taught for many years by Henry Borsook, who was about to retire. Students dreaded this course. Having delighted in biochemistry during his graduate training at Stanford, he was determined to put…

Commentary: PhDs in biochemistry education-5 years later.

PubMed

Offerdahl, Erika G; Momsen, Jennifer L; Osgood, Marcy

2014-01-01

In this commentary, the discussion of PhDs in biochemistry education research is expanded to explore a number of diverse pathways leading to a competitive research program in biochemistry education research. © 2013 by The International Union of Biochemistry and Molecular Biology.

Medical Biochemistry as Subdiscipline of Laboratory Medicine in Serbia.

PubMed

Jovičić, Snežana; Majkić-Singh, Nada

2017-04-01

Medical biochemistry is the usual name for clinical biochemistry or clinical chemistry in Serbia, and medical biochemist is the official name for the clinical chemist (or clinical biochemist). This is the largest sub-discipline of the laboratory medicine in Serbia. It includes all aspects of clinical chemistry, and also laboratory hematology with coagulation, immunology, etc. Medical biochemistry laboratories in Serbia and medical biochemists as a profession are part of Health Care System and their activities are regulated through: the Health Care Law and rules issued by the Chamber of Medical Biochemists of Serbia. The first continuous and organized education for Medical Biochemists (Clinical Chemists) in Serbia dates from 1945, when the Department of Medical Biochemistry was established at the Pharmaceutical Faculty in Belgrade. In 1987 at the same Faculty a five years undergraduate study program was established, educating Medical Biochemists under a special program. Since the academic year 2006/2007 the new five year undergraduate (according to Bologna Declaration) and four-year postgraduate program according to EC4 European Syllabus for Postgraduate Training in Clinical Chemistry and Laboratory Medicine has been established. The Ministry of Education and Ministry of Public Health accredited these programs. There are four requirements for practicing medical biochemistry in the Health Care System: University Diploma of the Faculty of Pharmacy (Study of Medical Biochemistry), successful completion of the professional exam at the Ministry of Health after completion of one additional year of obligatory practical training in the medical biochemistry laboratories, membership in the Serbian Chamber of Medical Biochemists and licence for skilled work issued by the Serbian Chamber of Medical Biochemists. In order to present laboratory medical biochemistry practice in Serbia this paper will be focused on the following: Serbian national legislation, healthcare services

Medical Biochemistry as Subdiscipline of Laboratory Medicine in Serbia

PubMed Central

Jovičić, Snežana

2017-01-01

Summary Medical biochemistry is the usual name for clinical biochemistry or clinical chemistry in Serbia, and medical biochemist is the official name for the clinical chemist (or clinical biochemist). This is the largest sub-discipline of the laboratory medicine in Serbia. It includes all aspects of clinical chemistry, and also laboratory hematology with coagulation, immunology, etc. Medical biochemistry laboratories in Serbia and medical biochemists as a profession are part of Health Care System and their activities are regulated through: the Health Care Law and rules issued by the Chamber of Medical Biochemists of Serbia. The first continuous and organized education for Medical Biochemists (Clinical Chemists) in Serbia dates from 1945, when the Department of Medical Biochemistry was established at the Pharmaceutical Faculty in Belgrade. In 1987 at the same Faculty a five years undergraduate study program was established, educating Medical Biochemists under a special program. Since the academic year 2006/2007 the new five year undergraduate (according to Bologna Declaration) and four-year postgraduate program according to EC4 European Syllabus for Postgraduate Training in Clinical Chemistry and Laboratory Medicine has been established. The Ministry of Education and Ministry of Public Health accredited these programs. There are four requirements for practicing medical biochemistry in the Health Care System: University Diploma of the Faculty of Pharmacy (Study of Medical Biochemistry), successful completion of the professional exam at the Ministry of Health after completion of one additional year of obligatory practical training in the medical biochemistry laboratories, membership in the Serbian Chamber of Medical Biochemists and licence for skilled work issued by the Serbian Chamber of Medical Biochemists. In order to present laboratory medical biochemistry practice in Serbia this paper will be focused on the following: Serbian national legislation, healthcare

15th Annual Expeditionary Warfare Conference - Expeditionary Operations - What’s Next

DTIC Science & Technology

2010-10-07

00 PM - 5:00 PM Mine Warfare Capabilities Essential for Expeditionary Warfare Salon 1 (limited to first 120 registrants) Session Focus...have priority – Requires additional conceptual development, gaming & exercises Questions? 23

Use of General Principles in Teaching Biochemistry.

ERIC Educational Resources Information Center

Fernandez, Rolando Hernandez; Tomey, Agustin Vicedo

1991-01-01

Presents Principles of Biochemistry for use as main focus of a biochemistry course. The nine guiding ideas are the principles of continual turnover, macromolecular organization, molecular recognition, multiplicity of utilization, maximum efficiency, gradual change, interrelationship, transformational reciprocity, and information transfer. In use…

Immobilized alpha-Galactosidase in the Biochemistry Laboratory

ERIC Educational Resources Information Center

Mulimani, V. H.; Dhananjay, K.

2007-01-01

This laboratory experiment was designed to demonstrate the application of immobilized galactosidase in food industry to hydrolyze raffinose family oligosaccharides in soymilk. This laboratory experiment was conducted for postgraduate students of biochemistry and developed for graduate and undergraduate students of biochemistry, biotechnology,…

Writing throughout the biochemistry curriculum: Synergistic inquiry-based writing projects for biochemistry students.

PubMed

Mertz, Pamela; Streu, Craig

2015-01-01

This article describes a synergistic two-semester writing sequence for biochemistry courses. In the first semester, students select a putative protein and are tasked with researching their protein largely through bioinformatics resources. In the second semester, students develop original ideas and present them in the form of a research grant proposal. Both projects involve multiple drafts and peer review. The complementarity of the projects increases student exposure to bioinformatics and literature resources, fosters higher-order thinking skills, and develops teamwork and communication skills. Student feedback and responses on perception surveys demonstrated that the students viewed both projects as favorable learning experiences. © 2015 The International Union of Biochemistry and Molecular Biology.

Status of dental health in chemical warfare victims: the case of Isfahan, Iran.

PubMed

Mottaghi, Ahmad; Hoseinzade, Abolfath; Zamani, Elham; Araghizade, Habib Allah

2012-01-01

Little evidence is available regarding the dental health of victims of chemical warfare in Iran. Therefore, in this study, we examined the decayed, missing, and filled teeth index (DMFT), community periodontal index of treatment needs (CPITN), and saliva secretion rate of chemical warfare victims living in the province of Isfahan in Iran. This case-control study was conducted with 300 chemical warfare victims as the treatment group and 300 age-matched individuals without exposure to chemical warfare as the control group. DMFT and CPITN indices and saliva secretion rate were measured and compared between the two groups. Chemical warfare victims had significantly higher scores than the control group for decayed teeth (4.25 ± 3.88 vs 3.52 ± 2.81; P=0.009), missing teeth (8.79 ± 9.3 vs 6.15 ± 8.43; P<0.001), total DMFT index (17.00 ± 6.72 vs 13.20 ± 6.89; P<0.001), and CPTIN (2.81 ± 0.81 vs 1.71 ± 1.04; P<0.001). However, no significant difference was observed between the two groups in filled teeth (4.00 ± 4.2 vs 3.59 ± 2.48; P=0.148). The level of saliva secretion in warfare victims was significantly lower than that in the control group (1.71 ± 0.05 vs 3.85 ± 1.95 cc/5 min; P<0.001). Chemical warfare victims have relatively poor dental/oral health. Chemical injury might cause a dysfunction in saliva secretion, with decrease in saliva secretion increasing the risk for tooth decay and periodontal disorders. Further research is required to find out the exact underlying mechanisms and the factors associated with poor dental/oral health in chemical warfare victims.

LESSONS FROM THE FRONT: A CASE STUDY OF RUSSIAN CYBER WARFARE

DTIC Science & Technology

2015-12-01

Lessons From The Front: A Case Study Of Russian Cyber Warfare looks to capitalize on the lessons learned from the alleged Russian cyber-offensive on...through the careful analysis and comparison of two disparate conflicts related by their collision with Russian cyber - warfare . Following case study

Air Force Cyber Warfare: Now and the Future

DTIC Science & Technology

2013-10-01

cyber warfare in popular culture. Most of them focus on the individual s uncanny grasp of technology the ability to exploit any system with a dizzying flurry of keystrokes or to fend off adversaries with a smartphone, a paper clip, and an ingenious plan. These socially awkward heroes and heroines fill the silver screen with visions of a new kind of warfare. Contradicting these stereotypes, Air Force cyber operations are carefully planned and controlled by disciplined, rigorously trained operators. Rather than acting alone, these professionals produce effects in support of

Navy Operational Planner: Anti-Submarine Warfare with Time-Dependent Performance

DTIC Science & Technology

2017-09-01

PLANNER: ANTI-SUBMARINE WARFARE WITH TIME -DEPENDENT PERFORMANCE by Anthony M. Baldessari September 2017 Thesis Advisor: W. Matthew...reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instruction, searching...REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE NAVY OPERATIONAL PLANNER: ANTI-SUBMARINE WARFARE WITH TIME -DEPENDENT

US Army Special Warfare. Its Origins: Psychological and Unconventional Warfare, 1941-1952

DTIC Science & Technology

1982-01-01

remained a fundamental military organization. Simultaneously, however, a few thinkers began to consider the possibility of forces capable of operating at...guerrilla warfare. He had been impressed as well by the British system of intelligence and counter- intelligence, as conducted by their Secret Intelligence...highly respected Columbia Broadcasting System reporter like Elmer Davis as its first director. Although most existing information services were trans

BOREAS TE-9 NSA Canopy Biochemistry

NASA Technical Reports Server (NTRS)

Hall, Forrest G. (Editor); Curd, Shelaine (Editor); Margolis, Hank; Charest, Martin; Sy, Mikailou

2000-01-01

The BOREAS TE-9 team collected several data sets related to chemical and photosynthetic properties of leaves. This data set contains canopy biochemistry data collected in 1994 in the NSA at the YJP, OJR, OBS, UBS, and OA sites, including biochemistry lignin, nitrogen, cellulose, starch, and fiber concentrations. These data were collected to study the spatial and temporal changes in the canopy biochemistry of boreal forest cover types and how a high-resolution radiative transfer model in the mid-infrared could be applied in an effort to obtain better estimates of canopy biochemical properties using remote sensing. The data are available in tabular ASCII files. The data files are available on a CD-ROM (see document number 20010000884), or from the Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC).

About the bears and the bees: Adaptive responses to asymmetric warfare

NASA Astrophysics Data System (ADS)

Ryan, Alex

Conventional military forces are organised to generate large scale effects against similarly structured adversaries. Asymmetric warfare is a 'game' between a conventional military force and a weaker adversary that is unable to match the scale of effects of the conventional force. In asymmetric warfare, an insurgents' strategy can be understood using a multi-scale perspective: by generating and exploiting fine scale complexity, insurgents prevent the conventional force from acting at the scale they are designed for. This paper presents a complex systems approach to the problem of asymmetric warfare, which shows how future force structures can be designed to adapt to environmental complexity at multiple scales and achieve full spectrum dominance.

About the bears and the bees: Adaptive responses to asymmetric warfare

NASA Astrophysics Data System (ADS)

Ryan, Alex

Conventional military forces are organised to generate large scale effects against similarly structured adversaries. Asymmetric warfare is a `game' between a conventional military force and a weaker adversary that is unable to match the scale of effects of the conventional force. In asymmetric warfare, an insurgents' strategy can be understood using a multi-scale perspective: by generating and exploiting fine scale complexity, insurgents prevent the conventional force from acting at the scale they are designed for. This paper presents a complex systems approach to the problem of asymmetric warfare, which shows how future force structures can be designed to adapt to environmental complexity at multiple scales and achieve full spectrum dominance.

Fluorescent sensors for the detection of chemical warfare agents.

PubMed

Burnworth, Mark; Rowan, Stuart J; Weder, Christoph

2007-01-01

Along with biological and nuclear threats, chemical warfare agents are some of the most feared weapons of mass destruction. Compared to nuclear weapons they are relatively easy to access and deploy, which makes them in some aspects a greater threat to national and global security. A particularly hazardous class of chemical warfare agents are the nerve agents. Their rapid and severe effects on human health originate in their ability to block the function of acetylcholinesterase, an enzyme that is vital to the central nervous system. This article outlines recent activities regarding the development of molecular sensors that can visualize the presence of nerve agents (and related pesticides) through changes of their fluorescence properties. Three different sensing principles are discussed: enzyme-based sensors, chemically reactive sensors, and supramolecular sensors. Typical examples are presented for each class and different fluorescent sensors for the detection of chemical warfare agents are summarized and compared.

The Physics of Warfare

ERIC Educational Resources Information Center

Giordano, Gerardo

2015-01-01

Recently, I was tasked with the creation and execution of a new themed general education physics class called The Physics of Warfare. In the past, I had used the theme of a class, such as the physics of sports medicine, as a way to create homework and in-class activities, generate discussions, and provide an application to demonstrate that physics…

"No practical capabilities": American biological and chemical warfare programs during the Korean war.

PubMed

Crane, Conrad C

2002-01-01

Much controversy still surrounds accusations that American forces in the Far East during the Korean War used biological warfare against North Korea and China. An analysis of recently declassified documents reveals that, although the United States attempted to accelerate its development and acquisition of such weapons during that period, its efforts to create a viable biological warfare capability were unsuccessful. Plans to similarly expand chemical warfare stocks and capabilities were also frustrated. Technological difficulties, personnel shortages, bureaucratic battles between the armed services, and policy limitations combined to hold back advances in American chemical and biological warfare. In light of the recent fears of terrorist attacks with such weapons, this analysis highlights the great difficulties involved in developing, acquiring, and delivering such capabilities.

Technological advancements for the detection of and protection against biological and chemical warfare agents.

PubMed

Eubanks, Lisa M; Dickerson, Tobin J; Janda, Kim D

2007-03-01

There is a growing need for technological advancements to combat agents of chemical and biological warfare, particularly in the context of the deliberate use of a chemical and/or biological warfare agent by a terrorist organization. In this tutorial review, we describe methods that have been developed both for the specific detection of biological and chemical warfare agents in a field setting, as well as potential therapeutic approaches for treating exposure to these toxic species. In particular, nerve agents are described as a typical chemical warfare agent, and the two potent biothreat agents, anthrax and botulinum neurotoxin, are used as illustrative examples of potent weapons for which countermeasures are urgently needed.

CYBER WARFARE GOVERNANCE: EVALUATION OF CURRENT INTERNATIONAL AGREEMENTS ON THE OFFENSIVE USE OF CYBER

DTIC Science & Technology

2015-10-01

AIR COMMAND AND STAFF COLLEGE DISTANCE LEARNING AIR UNIVERSITY CYBER WARFARE GOVERNANCE: EVALUATION OF CURRENT INTERNATIONAL AGREEMENTS ON THE...order to prevent catastrophic second and third order effects. Rule 43 “prohibits means or methods of cyber warfare that indiscriminate by nature...Means and methods of cyber warfare are indiscriminate by nature if they cannot be: directed at a specific military objective, or limited in their

Identification of threshold concepts for biochemistry.

PubMed

Loertscher, Jennifer; Green, David; Lewis, Jennifer E; Lin, Sara; Minderhout, Vicky

2014-01-01

Threshold concepts (TCs) are concepts that, when mastered, represent a transformed understanding of a discipline without which the learner cannot progress. We have undertaken a process involving more than 75 faculty members and 50 undergraduate students to identify a working list of TCs for biochemistry. The process of identifying TCs for biochemistry was modeled on extensive work related to TCs across a range of disciplines and included faculty workshops and student interviews. Using an iterative process, we prioritized five concepts on which to focus future development of instructional materials. Broadly defined, the concepts are steady state, biochemical pathway dynamics and regulation, the physical basis of interactions, thermodynamics of macromolecular structure formation, and free energy. The working list presented here is not intended to be exhaustive, but rather is meant to identify a subset of TCs for biochemistry for which instructional and assessment tools for undergraduate biochemistry will be developed. © 2014 J. Loertscher et al. CBE—Life Sciences Education © 2014 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

Strategic Analysis of Irregular Warfare

DTIC Science & Technology

2010-03-01

the same mathematical equations used by Lanchester .10 Irregular Warfare Theory and Doctrine It is time to develop new analytical methods and models...basis on which to build, similar to what Lanchester provided almost 100 years ago. Figure 9 portrays both Lanchester’s approach and an irregular 17

Sources of Occupational Stress and Prevalence of Burnout and Clinical Distress Among U.S. Air Force Cyber Warfare Operators

DTIC Science & Technology

2013-01-01

distress within the cyber warfare community. This study involved cyber warfare operators including active duty (n = 376) and civilian contractor and...revealed that when compared to civilian cyber warfare operators, active duty cyber warfare operators are more likely to suffer from the facets of...8217 write-in responses revealed cyber warfare operators attributed shift work, shift changes, and hours worked as the primary sources of high occupational

Raising environmental awareness through applied biochemistry laboratory experiments.

PubMed

Salman Ashraf, S

2013-01-01

Our environment is under constant pressure and threat from various sources of pollution. Science students, in particular chemistry students, must not only be made aware of these issues, but also be taught that chemistry (and science) can provide solutions to such real-life issues. To this end, a newly developed biochemistry laboratory experiment is described that guides students to learn about the applicability of peroxidase enzymes to degrade organic dyes (as model pollutants) in simulated waste water. In addition to showing how enzymes can potentially be used for waste water remediation, various factors than can affect enzyme-based reactions such as pH, temperature, concentration of substrates/enzymes, and denaturants can also be tested. This "applied biotechnology" experiment was successfully implemented in an undergraduate biochemistry laboratory course to enhance students' learning of environmental issues as well important biochemistry concepts. Student survey confirmed that this laboratory experiment was successful in achieving the objectives of raising environmental awareness in students and illustrating the usefulness of chemistry in solving real-life problems. This experiment can be easily adopted in an introductory biochemistry laboratory course and taught as an inquiry-guided exercise. © 2013 by The International Union of Biochemistry and Molecular Biology.

The Airpower Advantage in Future Warfare: The Need for Strategy

DTIC Science & Technology

2007-12-01

political situation which gener- ates war and therefore warfare, foreign and domestic; the social- cultural ideologies , attitudes, habits of mind, and...the ideological rivalries that contributed so powerfully to interstate rivalry, ambition, and anxiety are all but defunct, save only in two respects...instead to fit that still improving competence into a truly holistic approach to warfare. That approach, in its turn, needs to fit into a genu - inely

Sub state Unconventional Warfare: Expanding United States Military Political Options

DTIC Science & Technology

2016-05-26

phases due to competing incumbent efforts. Giap was influenced in his understanding of revolutionary war phasing by Sun Tzu who Giap called one of his...Challenge of Unconventional Warfare. London: Routledge, 2012. Ames, Roger T. Sun - Tzu The Art of Warfare. New York: Ballantine Books, 1993. Amin, Samir...Guerrilla: Insurgents, Patriots, and Terrorists from Sun Tzu to Bin Laden. London: Brassey’s Inc., 2004. Rosenau, William, Subversion and Insurgency

Oceanography and Mine Warfare

DTIC Science & Technology

2000-03-13

of breaking waves , the position and strength of surface currents, and the propagation of the tide into very shallow waters. In the surf zone...6) sediment properties determine shock wave propagation , a method for mine neutralization in the surf zone. 48 OCEANOGRAPHY AND MINE WARFARE...mines will be buried in the sediments, sedimentary explosive shock wave propagation is critical for determining operational performance. Presently, we

Teaching Biochemistry Online at Oregon State University

ERIC Educational Resources Information Center

Ahern, Kevin

2017-01-01

A strategy for growing online biochemistry courses is presented based on successes in ecampus at Oregon State University. Four free drawing cards were key to the effort--YouTube videos, iTunes U online free course content, an Open Educational Resource textbook--Biochemistry Free and Easy, and a fun set of educational songs known as the Metabolic…

CUREs in biochemistry-where we are and where we should go.

PubMed

Bell, Jessica K; Eckdahl, Todd T; Hecht, David A; Killion, Patrick J; Latzer, Joachim; Mans, Tamara L; Provost, Joseph J; Rakus, John F; Siebrasse, Erica A; Ellis Bell, J

2017-01-02

Integration of research experience into classroom is an important and vital experience for all undergraduates. These course-based undergraduate research experiences (CUREs) have grown from independent instructor lead projects to large consortium driven experiences. The impact and importance of CUREs on students at all levels in biochemistry was the focus of a National Science Foundation funded think tank. The state of biochemistry CUREs and suggestions for moving biochemistry forward as well as a practical guide (supplementary material) are reported here. © 2016 by The International Union of Biochemistry and Molecular Biology, 45(1):7-12, 2017. © 2016 The Authors Biochemistry and Molecular Biology Education published by Wiley Periodicals, Inc. on behalf of International Union of Biochemistry and Molecular Biology.

Nutritional Biochemistry

NASA Technical Reports Server (NTRS)

Smith, Scott M.

2010-01-01

This slide presentation reviews some of the effects that space flight has on humans nutritional biochemistry. Particular attention is devoted to the study of protein breakdown, inflammation, hypercatabolism, omega 3 fatty acids, vitamin D, calcium, urine, folate and nutrient stability of certain vitamins, the fluid shift and renal stone risk, acidosis, iron/hematology, and the effects on bone of dietary protein, potassium. inflammation, and omega-3 fatty acids

Gray Zone Warfare: German and Russian Political Warfare, 1935-1939, and 2001

DTIC Science & Technology

2017-06-09

Stretching and Exploiting Thresholds for High -Order War: How Russia, China, and Iran are Eroding American Influence Using Time-Tested Measures...PSYOP Terminology,” in American Institutes for Research, Department of the Army Pamphlet 525-7-1-2, The Art and Science of Psychological Operations...efforts to attack the enemies’ “ power , influence, and will.”88 In the United States, Irregular Warfare was not a part of doctrine until 2007, when the

Cyberspace as a Complex Adaptive System and the Policy and Operational Implications for Cyber Warfare

DTIC Science & Technology

2014-05-22

CYBERSPACE AS A COMPLEX ADAPTIVE SYSTEM AND THE POLICY AND OPERTIONAL IMPLICATIONS FOR CYBER WARFARE A Monograph by Major Albert O. Olagbemiro...serves the US, especially in regards to the protect ion o f the 1S. SUBJECT TERMS omplex Adaptive System, Cyberspace, lnfosphere, Cyber Warfare ber...System and the Policy and Operational Implications for Cyber Warfare Approved by: __________________________________, Monograph Director Jeffrey

Metal organic frameworks for the catalytic detoxification of chemical warfare nerve agents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hupp, Joseph T.; Farha, Omar K.; Katz, Michael J.

A method of using a metal organic framework (MOF) comprising a metal ion and an at least bidendate organic ligand to catalytically detoxify chemical warfare nerve agents including exposing the metal-organic-framework (MOF) to the chemical warfare nerve agent and catalytically decomposing the nerve agent with the MOF.

Effective Laboratory Work in Biochemistry Subject: Students' and Lecturers' Perspective in Indonesia

ERIC Educational Resources Information Center

Anwar, Yunita Arian Sani; Senam; Laksono F. X., Endang Widjajanti

2017-01-01

Biochemistry subject had problem in learning and teaching, especially in laboratory work. We explored laboratory learning implementation in Biochemistry subject. Participants of this research were 195 students who took biochemistry subject and 4 lecturers of biochemistry in three universities in Indonesia. We obtained data using questionnaires and…

Chemical warfare and the Gulf War: a review of the impact on Gulf veterans' health.

PubMed

Riddle, James R; Brown, Mark; Smith, Tyler; Ritchie, Elspeth Cameron; Brix, Kelley Ann; Romano, James

2003-08-01

It is unlikely that Gulf War veterans are suffering chronic effects from illnesses caused by chemical warfare nerve agent exposure. Extensive investigation and review by several expert panels have determined that no evidence exists that chemical warfare nerve agents were used during the Gulf War. At no time before, during, or after the war was there confirmation of symptoms among anyone, military or civilian, caused by chemical warfare nerve agent exposure. However, studies of Gulf War veterans have found belief that chemical weapons were used, significantly associated with both severe and mild-moderate illnesses. The psychological impact of a chemical warfare attack, either actual or perceived, can result in immediate and long-term health consequences. The deployment or war-related health impact from life-threatening experiences of the Gulf War, including the perceived exposure to chemical warfare agents, should be considered as an important cause of morbidity among Gulf War veterans.

Chemical and biological warfare: General studies. (Latest citations from the NTIS bibliographic database). NewSearch

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-10-01

The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology. (Contains 250 citations and includes a subject term index andmore » title list.)« less

Intelligence, Information Technology, and Information Warfare.

ERIC Educational Resources Information Center

Davies, Philip H. J.

2002-01-01

Addresses the use of information technology for intelligence and information warfare in the context of national security and reviews the status of clandestine collection. Discusses hacking, human agent collection, signal interception, covert action, counterintelligence and security, and communications between intelligence producers and consumers…

Oxidative decontamination of chemical and biological warfare agents using L-Gel.

PubMed

Raber, Ellen; McGuire, Raymond

2002-08-05

A decontamination method has been developed using a single reagent that is effective both against chemical warfare (CW) and biological warfare (BW) agents. The new reagent, "L-Gel", consists of an aqueous solution of a mild commercial oxidizer, Oxone, together with a commercial fumed silica gelling agent, Cab-O-Sil EH-5. L-Gel is non-toxic, environmentally friendly, relatively non-corrosive, maximizes contact time because of its thixotropic nature, clings to walls and ceilings, and does not harm carpets or painted surfaces. The new reagent also addresses the most demanding requirements for decontamination in the civilian sector, including availability, low maintenance, ease of application and deployment by a variety of dispersal mechanisms, minimal training and acceptable expense. Experiments to test the effectiveness of L-Gel were conducted at Lawrence Livermore National Laboratory and independently at four other locations. L-Gel was tested against all classes of chemical warfare agents and against various biological warfare agent surrogates, including spore-forming bacteria and non-virulent strains of real biological agents. Testing showed that L-Gel is as effective against chemical agents and biological materials, including spores, as the best military decontaminants.

Commentary: PhDs in Biochemistry Education--5 Years Later

ERIC Educational Resources Information Center

Offerdahl, Erika G.; Momsen, Jennifer L.; Osgood, Marcy

2014-01-01

In this commentary, the discussion of PhDs in biochemistry education research is expanded to explore a number of diverse pathways leading to a competitive research program in biochemistry education research.

Efficacy Evaluation of Current and Future Naval Mine Warfare Neutralization Method

DTIC Science & Technology

2016-12-01

Distribution is unlimited. EFFICACY EVALUATION OF CURRENT AND FUTURE NAVAL MINE WARFARE NEUTRALIZATION METHOD by Team MIW Cohort SE311-152O...EFFICACY EVALUATION OF CURRENT AND FUTURE NAVAL MINE WARFARE NEUTRALIZATION METHOD 5. FUNDING NUMBERS 6. AUTHOR (S) Team MIW, Systems Engineering...NEUTRALIZATION METHOD Team MIW, Systems Engineering Cohort SE311-152O Submitted in partial fulfillment of the requirements for the degrees of

Calming the Churn: Resolving the Dilemma of Rotational Warfare in Counterinsurgency

DTIC Science & Technology

2013-12-01

warfare in counterinsurgency Publisher Monterey, California: Naval Postgraduate School Issue Date 2013-12 URL http://hdl.handle.net/10945/38873... TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE CALMING THE CHURN: RESOLVING THE DILEMMA OF ROTATIONAL WARFARE IN COUNTERINSURGENCY...operations, however, would not last and, after only a year, MacArthur was sent to other duties thanks to personality conflicts with Taft. His replacement

Rethinking Cultural Influences on Warfare

DTIC Science & Technology

2012-05-17

36 Jarole B. Manheim, Richard C. Lars Willnat, and Craig Brians , Empirical Political...Willnat, and Craig Brians , Empirical Political Analysis: Quantitative and Qualitative Research Methods (New York: Pearson Education Inc, 2008... Boxer Rebellions. In 1950, China was emerging from 13 years of protracted warfare with Japan and a civil war between the Chinese Communist Party (CCP

Coalition Warfare: the Leadership Challenges

DTIC Science & Technology

2011-05-19

Approved for Public Release; Distribution is Unlimited Coalition Warfare: The leadership challenges A Monograph by Colonel Mark J Thornhill...The leadership challenges . 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Colonel Mark J. Thornhill...multinational operations, leadership challenges , leadership attributes, unity of command. 16. SECURITY CLASSIFICATION OF: UNCLASSIFIED 17. LIMITATION OF

A 13-Week Research-Based Biochemistry Laboratory Curriculum

ERIC Educational Resources Information Center

Lefurgy, Scott T.; Mundorff, Emily C.

2017-01-01

Here, we present a 13-week research-based biochemistry laboratory curriculum designed to provide the students with the experience of engaging in original research while introducing foundational biochemistry laboratory techniques. The laboratory experience has been developed around the directed evolution of an enzyme chosen by the instructor, with…

Reproduction, physiology and biochemistry

USDA-ARS?s Scientific Manuscript database

This chapter summarizes fundamental knowledge and recent discoveries about the reproduction, physiology and biochemistry of plant-parasitic nematodes. Various types of reproduction are reviewed, including sexual reproduction and mitotic and meiotic parthenogenesis. Although much is known about the p...

Chemical and biological warfare: General studies. (Latest citations from the NTIS bibliographic database). Published Search

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-11-01

The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology.(Contains 50-250 citations and includes a subject term index and titlemore » list.) (Copyright NERAC, Inc. 1995)« less

Chemical and biological warfare: General studies. (Latest citations from the NTIS bibliographic database). Published Search

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-10-01

The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology. (Contains 50-250 citations and includes a subject term index andmore » title list.) (Copyright NERAC, Inc. 1995)« less

Chemical and biological warfare: General studies. (Latest citations from the NTIS bibliographic database). Published Search

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-09-01

The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology.(Contains 50-250 citations and includes a subject term index and titlemore » list.) (Copyright NERAC, Inc. 1995)« less

Enhanced Podcasts for Teaching Biochemistry to Veterinary Students

ERIC Educational Resources Information Center

Gough, Kevin C.

2011-01-01

The teaching of biochemistry within medical disciplines presents certain challenges; firstly to relay a large body of complex facts and abstract concepts, and secondly to motivate students that this relatively difficult topic is worth their time to study. Here, nutrient biochemistry was taught within a multidisciplinary module as part of an…

Antidotes and treatments for chemical warfare/terrorism agents: an evidence-based review.

PubMed

Rodgers, G C; Condurache, C T

2010-09-01

This article reviews the evidence supporting the efficacy of antidotes used or recommended for the potential chemical warfare agents of most concern. Chemical warfare agents considered include cyanide, vesicants, pulmonary irritants such as chlorine and phosgene, and nerve agents. The strength of evidence for most antidotes is weak, highlighting the need for additional research in this area.

Remaining Relevant: Historical Contributions, Civil-Military Challenges, and Anti-Submarine Warfare Capabilities on Coast Guard Cutters

DTIC Science & Technology

2018-03-01

HISTORICAL CONTRIBUTIONS, CIVIL-MILITARY CHALLENGES, AND ANTI-SUBMARINE WARFARE CAPABILITIES ON COAST GUARD CUTTERS by Brian A. Smicklas...CONTRIBUTIONS, CIVIL- MILITARY CHALLENGES, AND ANTI-SUBMARINE WARFARE CAPABILITIES ON COAST GUARD CUTTERS 5. FUNDING NUMBERS 6. AUTHOR(S) Brian A...MILITARY CHALLENGES, AND ANTI-SUBMARINE WARFARE CAPABILITIES ON COAST GUARD CUTTERS Brian A. Smicklas Commander, U.S. Coast Guard B.S., Coast

Estimated Chemical Warfare Agent Surface Clearance Goals for Remediation Pre-Planning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dolislager, Frederick; Bansleben, Dr. Donald; Watson, Annetta Paule

2010-01-01

Health-based surface clearance goals, in units of mg/cm2, have been developed for the persistent chemical warfare agents sulfur mustard (HD) and nerve agent VX as well as their principal degradation products. Selection of model parameters and critical receptor (toddler child) allow calculation of surface residue estimates protective for the toddler child, the general population and adult employees of a facilty that has undergone chemical warfare agent attack.

The Strategic and Political Impacts of Collateral Damage from Strike Warfare

DTIC Science & Technology

2015-03-01

damage from strike warfare focuses on legal, humanitarian, and moral issues . To oversimplify, killing non-combatants is bad, but it happens, and not...humanitarian, and moral issues . To oversimplify, killing non- combatants is bad, but it happens, and not always by accident. Therefore, it is instructive...method of bombing. A significant amount of research on the effects of collateral damage from strike warfare focuses on humanitarian and moral issues

Gender Differences in the Impact of Warfare Exposure on Self-Rated Health

PubMed Central

Wang, Joyce M.; Lee, Lewina O.; Spiro, Avron

2014-01-01

BACKGROUND This study examined gender differences in the impact of warfare exposure on self-reported physical health. METHODS Data are from the 2010 National Survey of Veterans, a nationally representative survey of veterans from multiple eras of service. Regression analyses assessed gender differences in the association between warfare exposure (deployment to a war zone, exposure to casualties) and health status and functional impairment, adjusting for sociodemographics. FINDINGS Women reported better health status but greater functional impairment than men. In men, those who experienced casualties only or both casualties and deployment to a war zone had worse health compared to those who experienced neither stressor or deployment to a war zone only. In women, those who experienced casualties only or both stressors reported worse health than those who experienced war zone only, who did not differ from the unexposed. No association was found between warfare exposure and functional impairment in women, but in men, those who experienced exposure to casualties or both stressors had greater odds of functional impairment compared to those who experienced war zone only or neither stressor. CONCLUSIONS Exposure to casualties may be more predictive of health than deployment to a war zone, especially for men. We did not find a stronger association between warfare exposure and health for women than men. Given that the expansion of women's military roles has allowed them to serve in direct combat, their degree and scope of warfare exposure is likely to increase in the future. PMID:25442366

Technology Transition for Hybrid Warfare

DTIC Science & Technology

2010-02-16

and Iraq. At the same time, the science and technology base must provide the disruptive technologies to defeat future conventional enemies. This... disruptive technologies will be needed to retain long-term technological superiority in conventional warfare. Incremental improvement is the most...technology to be missed. Disruptive technologies are the second type of technological change and involve revolutionary concepts involving large technological

Can biochemistry drive drug discovery beyond simple potency measurements?

PubMed

Chène, Patrick

2012-04-01

Among the fields of expertise required to develop drugs successfully, biochemistry holds a key position in drug discovery at the interface between chemistry, structural biology and cell biology. However, taking the example of protein kinases, it appears that biochemical assays are mostly used in the pharmaceutical industry to measure compound potency and/or selectivity. This limited use of biochemistry is surprising, given that detailed biochemical analyses are commonly used in academia to unravel molecular recognition processes. In this article, I show that biochemistry can provide invaluable information on the dynamics and energetics of compound-target interactions that cannot be obtained on the basis of potency measurements and structural data. Therefore, an extensive use of biochemistry in drug discovery could facilitate the identification and/or development of new drugs. Copyright © 2012 Elsevier Ltd. All rights reserved.

Blaptica dubia as sentinels for exposure to chemical warfare agents - a pilot study.

PubMed

Worek, Franz; Seeger, Thomas; Neumaier, Katharina; Wille, Timo; Thiermann, Horst

2016-11-16

The increased interest of terrorist groups in toxic chemicals and chemical warfare agents presents a continuing threat to our societies. Early warning and detection is a key component for effective countermeasures against such deadly agents. Presently available and near term solutions have a number of major drawbacks, e.g. lack of automated, remote warning and detection of primarily low volatile chemical warfare agents. An alternative approach is the use of animals as sentinels for exposure to toxic chemicals. To overcome disadvantages of vertebrates the present pilot study was initiated to investigate the suitability of South American cockroaches (Blaptica dubia) as warning system for exposure to chemical warfare nerve and blister agents. Initial in vitro experiments with nerve agents showed an increasing inhibitory potency in the order tabun - cyclosarin - sarin - soman - VX of cockroach cholinesterase. Exposure of cockroaches to chemical warfare agents resulted in clearly visible and reproducible reactions, the onset being dependent on the agent and dose. With nerve agents the onset was related to the volatility of the agents. The blister agent lewisite induced signs largely comparable to those of nerve agents while sulfur mustard exposed animals exhibited a different sequence of events. In conclusion, this first pilot study indicates that Blaptica dubia could serve as a warning system to exposure of chemical warfare agents. A cockroach-based system will not detect or identify a particular chemical warfare agent but could trigger further actions, e.g. specific detection and increased protective status. By designing appropriate boxes with (IR) motion sensors and remote control (IR) camera automated off-site warning systems could be realized. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

78 FR 53109 - Security Zones; Naval Base Point Loma; Naval Mine Anti-Submarine Warfare Command; San Diego Bay...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-28

...-AA87 Security Zones; Naval Base Point Loma; Naval Mine Anti-Submarine Warfare Command; San Diego Bay... Anti-Submarine Warfare Command to protect the relocated marine mammal program. These security zone... Warfare Command, the Commander of Naval Region Southwest, or a designated representative of those...

Biochemistry Off the Shelf.

ERIC Educational Resources Information Center

Wilson, Jerry L.

1985-01-01

Provides sources of nonanimal biochemical materials (which are relatively inexpensive, readily available, and require no special storage) suitable for use in biochemistry experiments. They are presented under these headings: (1) enzymes and other proteins; (2) carbohydrates; (3) lipids; (4) nucleic acids; and (5) metabolism. (JN)

Neglected issues concerning teaching human adrenal steroidogenesis in popular biochemistry textbooks.

PubMed

Han, Zhiyong; Elliott, Mark S

2017-11-01

In the human body, the adrenal steroids collectively regulate a plethora of fundamental functions, including electrolyte and water balance, blood pressure, stress response, intermediary metabolism, inflammation, and immunity. Therefore, adrenal steroidogenesis is an important biochemistry topic for students to learn in order for them to understand health consequences caused by deficiencies of enzymes in the adrenal steroidogenic pathways. However, popular biochemistry textbooks contain insufficient information and may sometimes give students a misimpression about certain aspects of human adrenal steroidogenesis. This article highlights two neglected issues in teaching human adrenal steroidogenesis in popular biochemistry textbooks. The purpose of this article is to draw attention to these issues. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(6):469-474, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

Technical Support Services for the Office of Naval Research Littoral Warfare Advanced Development Project

DTIC Science & Technology

2005-09-30

Technical Support Services for the Office of Naval Research Littoral Warfare Advanced Development Project William R. Metzger Marine...Support Services for the Office of Naval Research Littoral Warfare Advanced Development Project 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

Vertical integration of biochemistry and clinical medicine using a near-peer learning model.

PubMed

Gallan, Alexander J; Offner, Gwynneth D; Symes, Karen

2016-11-12

Vertical integration has been extensively implemented across medical school curricula but has not been widely attempted in the field of biochemistry. We describe a novel curricular innovation in which a near-peer learning model was used to implement vertical integration in our medical school biochemistry course. Senior medical students developed and facilitated a case-based small group session for first year biochemistry students. Students were surveyed before and after the session on their attitudes about biochemistry, as well as the effectiveness of the session. Prior to the session, the students believed biochemistry was more important to understanding the basic science of medicine than it was to understanding clinical medicine or becoming a good physician. The session improved students' attitudes about the importance of biochemistry in clinical medicine, and after the session they now believe that understanding biochemistry is equally important to the basic sciences as clinical medicine. Students would like more sessions and believe the senior student facilitators were knowledgeable and effective teachers. The facilitators believe they improved their teaching skills. This novel combination of near-peer learning and vertical integration in biochemistry provided great benefit to both first year and senior medical students, and can serve as a model for other institutions. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(6):507-516, 2016. © 2016 The International Union of Biochemistry and Molecular Biology.

Electronic Warfare and Radar Systems Engineering Handbook

DTIC Science & Technology

1999-04-01

EWRL Electronic Warfare Reprogrammable ELNOT Emitter Library Notation Library (USN) EM Electromagnetic EWSI EW Systems Integration E-Mail Electronic...ram air turbine (RAT) propellers used to power aircraft pods, helicopter rotor blades, and protruding surfaces of automobile hubcaps will all provide

Special Operations And Cyber Warfare

DTIC Science & Technology

2016-12-01

with the high level of Soldier competency in the 95th for CA Soldiers to retrain and fulfill the cyber requirement. With the reorganization of the...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release. Distribution is unlimited. SPECIAL OPERATIONS AND CYBER...OPERATIONS AND CYBER WARFARE 5. FUNDING NUMBERS 6. AUTHOR(S) Jason C. Tebedo 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School

Gender differences in the impact of warfare exposure on self-rated health.

PubMed

Wang, Joyce M; Lee, Lewina O; Spiro, Avron

2015-01-01

This study examined gender differences in the impact of warfare exposure on self-reported physical health. Data are from the 2010 National Survey of Veterans, a nationally representative survey of veterans from multiple eras of service. Regression analyses assessed gender differences in the association between warfare exposure (deployment to a war zone, exposure to casualties) and health status and functional impairment, adjusting for sociodemographics. Women reported better health status but greater functional impairment than men. Among men, those who experienced casualties only or both casualties and deployment to a war zone had worse health compared with those who experienced neither stressor or deployment to a war zone only. Among women, those who experienced casualties only or both stressors reported worse health than those who experienced war zone only, who did not differ from the unexposed. No association was found between warfare exposure and functional impairment in women; in men, however, those who experienced exposure to casualties or both stressors had greater odds of functional impairment compared with those who experienced war zone only or neither stressor. Exposure to casualties may be more predictive of health than deployment to a war zone, especially for men. We did not find a stronger association between warfare exposure and health for women than men. Given that the expansion of women's military roles has allowed them to serve in direct combat, their degree and scope of warfare exposure is likely to increase in the future. Copyright © 2015 Jacobs Institute of Women's Health. All rights reserved.

Submarine Warfare in the 20th & 21st Centuries: A Bibliography

DTIC Science & Technology

2003-12-01

International studies series ser. no. 02-019). 49 p. Bailey, Thomas Andrew and Paul B. Ryan. The Lusitania disaster: an episode in modern warfare and...verlagshandlung, 1939. 212 p. Ellis, Frederick D. The tragedy of the Lusitania : embracing authentic stories by the survivors and eye-witnesses of the disaster...warfare; a study of its methods and spirit, including the crime of the " Lusitania ," a record of observations and evidence. New York, London, D. Appleton

Reciprocity within biochemistry and biology service-learning.

PubMed

Santas, Amy J

2009-05-01

Service-learning has become a popular pedagogy because of its numerous and far-reaching benefits (e.g. student interest, engagement, and retention). In part, the benefits are a result of the student learning while providing a service that reflects a true need-not simply an exercise. Although service-learning projects have been developed in the areas of Biochemistry and Biology, many do not require reciprocity between the student and those being served. A reciprocal relationship enables a depth in learning as students synthesize and integrate their knowledge while confronting a real-life need. A novel reciprocal service-learning project within a three-semester undergraduate research course in the areas of Biochemistry and Biology is presented. The goal of the project was agreed upon through joint meetings with the partner institution (The Wilds) to develop an in-house competitive ELISA pregnane diol assay. Student progress and achievements were followed through the use of rubrics and progress-meetings with The Wilds. A portfolio provided a visual of progress as it contained both the written assignments as well as the rubric. The article describes a specific reciprocal biochemistry and biology service-learning project and provides recommendations on how to adapt this service-learning design for use in other research courses. Copyright © 2009 International Union of Biochemistry and Molecular Biology, Inc.

A guide to using case-based learning in biochemistry education.

PubMed

Kulak, Verena; Newton, Genevieve

2014-01-01

Studies indicate that the majority of students in undergraduate biochemistry take a surface approach to learning, associated with rote memorization of material, rather than a deep approach, which implies higher cognitive processing. This behavior relates to poorer outcomes, including impaired course performance and reduced knowledge retention. The use of case-based learning (CBL) into biochemistry teaching may facilitate deep learning by increasing student engagement and interest. Abundant literature on CBL exists but clear guidance on how to design and implement case studies is not readily available. This guide provides a representative review of CBL uses in science and describes the process of developing CBL modules to be used in biochemistry. Included is a framework to implement a directed CBL assisted with lectures in a content-driven biochemistry course regardless of class size. Moreover, this guide can facilitate adopting CBL to other courses. Consequently, the information presented herein will be of value to undergraduate science educators with an interest in active learning pedagogies. © 2014 The International Union of Biochemistry and Molecular Biology.

Biochemistry at High School and University Levels in Saudi Arabia.

ERIC Educational Resources Information Center

Abu-Salah, Khalid M.; And Others

1988-01-01

Describes the assessment process for students in Saudi Arabia who are interested in pursuing a higher education in biochemistry. Provides recommendations for improving biochemistry education in both high schools and universities. (TW)

Circular dichroism spectroscopy: Enhancing a traditional undergraduate biochemistry laboratory experience.

PubMed

Lewis, Russell L; Seal, Erin L; Lorts, Aimee R; Stewart, Amanda L

2017-11-01

The undergraduate biochemistry laboratory curriculum is designed to provide students with experience in protein isolation and purification protocols as well as various data analysis techniques, which enhance the biochemistry lecture course and give students a broad range of tools upon which to build in graduate level laboratories or once they begin their careers. One of the most common biochemistry protein purification experiments is the isolation and characterization of cytochrome c. Students across the country purify cytochrome c, lysozyme, or some other well-known protein to learn these common purification techniques. What this series of experiments lacks is the use of sophisticated instrumentation that is rarely available to undergraduate students. To give students a broader background in biochemical spectroscopy techniques, a new circular dichroism (CD) laboratory experiment was introduced into the biochemistry laboratory curriculum. This CD experiment provides students with a means of conceptualizing the secondary structure of their purified protein, and assessments indicate that students' understanding of the technique increased significantly. Students conducted this experiment with ease and in a short time frame, so this laboratory is conducive to merging with other data analysis techniques within a single laboratory period. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(6):515-520, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

Quality of Life in Iranian Chemical Warfare Veteran's.

PubMed

Ebadi, Abbas; Moradian, Tayeb; Mollahadi, Mohsen; Saeed, Yaser; Refahi, Ali Akbar

2014-05-01

Mustard gas has different effects on different body systems such as respiratory tract, blood, gastrointestinal, skin, eye, endocrine and peripheral nervous system. The purpose of this study was to determine the quality of life in chemical warfare veterans due to sulfur mustard exposure. In a cross-sectional and analytic study, 242 patients who had a chemical injury during the Iran-Iraq war (1980-1983) and their lung damage was proven were investigated in our study. The quality of life was measured in these patients using an extensively validated Iranian version of SF-36. The mean age of veterans was 44.12 ± 4.9 ranging from 22 to 62 years. Our results showed that chemical warfare had a decreased quality of life in all subscales of the SF-36. The lowest scores in SF-36 subscales were related to role physical and general health. The data also showed a significant relationship between the number of organs involved and the quality of life in these patients (P < 0.001, r = - 0.33). So that the patients who had more than three organs involved had lower quality of life. 95.4% of our participants experienced another complication with respiratory complication and the ophthalmologic complications were the most frequent accompanying condition. The results imply that chemical warfare survivors suffering from late complications have a low health related quality of life.

78 FR 72025 - Security Zones; Naval Base Point Loma; Naval Mine Anti Submarine Warfare Command; San Diego Bay...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-02

...-AA87 Security Zones; Naval Base Point Loma; Naval Mine Anti Submarine Warfare Command; San Diego Bay... establishing a new security zone at the Naval Mine and Anti-Submarine Warfare Command to protect the relocated... Commander of Naval Base Point Loma, the Commander of the Naval Mine Anti Submarine Warfare Command, and the...

Metabolism and biochemistry in hypogravity

NASA Technical Reports Server (NTRS)

Leach, Carolyn S.

1991-01-01

The headward shift of body fluid and increase in stress-related hormones that occur in hypogravity bring about a number of changes in metabolism and biochemistry of the human body. Such alterations may have important effects on health during flight and during a recovery period after return to earth. Body fluid and electrolytes are lost, and blood levels of several hormones that control metabolism are altered during space flight. Increased serum calcium may lead to an increased risk of renal stone formation during flight, and altered drug metabolism could influence the efficacy of therapeutic agents. Orthostatic intolerance and an increased risk of fracturing weakened bones are concerns at landing. It is important to understand biochemistry and metabolism in hypogravity so that clinically important developments can be anticipated and prevented or ameliorated.

A Streamlined Molecular Biology Module for Undergraduate Biochemistry Labs

ERIC Educational Resources Information Center

Muth, Gregory W.; Chihade, Joseph W.

2008-01-01

Site-directed mutagenesis and other molecular biology techniques, including plasmid manipulation and restriction analysis, are commonly used tools in the biochemistry research laboratory. In redesigning our biochemistry lab curricula, we sought to integrate these techniques into a term-long, project-based course. In the module presented here,…

33 CFR 165.1103 - Security Zone; Naval Mine Anti Submarine Warfare Command; San Diego Bay, San Diego, CA.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Submarine Warfare Command; San Diego Bay, San Diego, CA. 165.1103 Section 165.1103 Navigation and Navigable... Eleventh Coast Guard District § 165.1103 Security Zone; Naval Mine Anti Submarine Warfare Command; San... the Naval Mine Anti Submarine Warfare Command, bound by the following coordinates: 32°43′40.9″ N, 117...

Moral Warfare in Counterinsurgency Operations

DTIC Science & Technology

2007-05-11

Moral Warfare in Counterinsurgency Operations A Monograph by MAJOR David C. Chiarenza US Army School of Advanced Military Studies United...OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 11-05-2007 2. REPORT TYPE AMSP Monograph 3...Public Release; Distribution is Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT This study explores the moral level of war in the context of

German Views of Irregular Warfare

DTIC Science & Technology

2015-06-01

closely observed much of the Napoleonic Wars (1803–1815). His military experiences occurred during the end of the Age of Absolutism10 in Europe when...10 The Age of Absolutism refers to a period when absolute monarchs controlled much of Europe and is commonly considered to...concluded with a chapter related to irregular warfare and the nuclear age and an appendix dedicated to the training notes of the famed English

Biochemistry Students' Ideas about Shape and Charge in Enzyme-Substrate Interactions

ERIC Educational Resources Information Center

Linenberger, Kimberly J.; Bretz, Stacey Lowery

2014-01-01

Biochemistry is a visual discipline that requires students to develop an understanding of numerous representations. However, there is very little known about what students actually understand about the representations that are used to communicate ideas in biochemistry. This study investigated biochemistry students' understanding of multiple…

Using augmented reality to teach and learn biochemistry.

PubMed

Vega Garzón, Juan Carlos; Magrini, Marcio Luiz; Galembeck, Eduardo

2017-09-01

Understanding metabolism and metabolic pathways constitutes one of the central aims for students of biological sciences. Learning metabolic pathways should be focused on the understanding of general concepts and core principles. New technologies such Augmented Reality (AR) have shown potential to improve assimilation of biochemistry abstract concepts because students can manipulate 3D molecules in real time. Here we describe an application named Augmented Reality Metabolic Pathways (ARMET), which allowed students to visualize the 3D molecular structure of substrates and products, thus perceiving changes in each molecule. The structural modification of molecules shows students the flow and exchange of compounds and energy through metabolism. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(5):417-420, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

Toward a global approach of biochemistry in hospitals.

PubMed

Boigne, J M; Moisdon, J C; Tonneau, D

1985-01-01

This article summarizes three different presentations delivered at the CRESGE congress by three members of GREBIO, a reflection group about biochemistry; created in the Paris hospitals, this group was concerned with these problems at a time of great technological change. Physicians, biochemists and administrators have been working in GREBIO for 7 years, with the methodological assistance of management from the School of Mines; they used new approaches, and careful investigations on the field and proposed analyses sometimes upsetting but always enriching the questionings. Starting from these results, briefly described, GREBIO proposed the creation of an observatory for biochemistry, that could take into account both the complexity and diversity in the laboratories. It also proposed that current reform in analytical accountancy allow biochemistry to work its own managing tools separately from accountancy purposes.

Incorporation of Bioinformatics Exercises into the Undergraduate Biochemistry Curriculum

ERIC Educational Resources Information Center

Feig, Andrew L.; Jabri, Evelyn

2002-01-01

The field of bioinformatics is developing faster than most biochemistry textbooks can adapt. Supplementing the undergraduate biochemistry curriculum with data-mining exercises is an ideal way to expose the students to the common databases and tools that take advantage of this vast repository of biochemical information. An integrated collection of…

U.S. Command Relationships in the Conduct of Cyber Warfare: Establishment, Exercise, and Institutionalization of Cyber Coordinating Authority

DTIC Science & Technology

2010-05-03

FINAL 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE U.S. Command Relationships in the Conduct of Cyber Warfare : Establishment...U.S. Command Relationships in the Conduct of Cyber Warfare : Establishment, Exercise, and Institutionalization of Cyber Coordinating Authority...Relationships in the Conduct of Cyber Warfare : Establishment, Exercise, and Institutionalization of Cyber Coordinating Authority The character of

Tissue-based water quality biosensors for detecting chemical warfare agents

DOEpatents

Greenbaum, Elias [Oak Ridge, TN; Sanders, Charlene A [Knoxville, TN

2003-05-27

A water quality sensor for detecting the presence of at least one chemical or biological warfare agent includes: a cell; apparatus for introducing water into the cell and discharging water from the cell adapted for analyzing photosynthetic activity of naturally occurring, free-living, indigenous photosynthetic organisms in water; a fluorometer for measuring photosynthetic activity of naturally occurring, free-living, indigenous photosynthetic organisms drawn into the cell; and an electronics package that analyzes raw data from the fluorometer and emits a signal indicating the presence of at least one chemical or biological warfare agent in the water.

Tissue-based standoff biosensors for detecting chemical warfare agents

DOEpatents

Greenbaum, Elias; Sanders, Charlene A.

2003-11-18

A tissue-based, deployable, standoff air quality sensor for detecting the presence of at least one chemical or biological warfare agent, includes: a cell containing entrapped photosynthetic tissue, the cell adapted for analyzing photosynthetic activity of the entrapped photosynthetic tissue; means for introducing an air sample into the cell and contacting the air sample with the entrapped photosynthetic tissue; a fluorometer in operable relationship with the cell for measuring photosynthetic activity of the entrapped photosynthetic tissue; and transmitting means for transmitting analytical data generated by the fluorometer relating to the presence of at least one chemical or biological warfare agent in the air sample, the sensor adapted for deployment into a selected area.

Computer-Assisted Performance Evaluation for Navy Anti-Air Warfare Training: Concepts, Methods, and Constraints.

ERIC Educational Resources Information Center

Chesler, David J.

An improved general methodological approach for the development of computer-assisted evaluation of trainee performance in the computer-based simulation environment is formulated in this report. The report focuses on the Tactical Advanced Combat Direction and Electronic Warfare system (TACDEW) at the Fleet Anti-Air Warfare Training Center at San…

Detection of biological warfare agents using ultra violet-laser induced fluorescence LIDAR

NASA Astrophysics Data System (ADS)

Joshi, Deepti; Kumar, Deepak; Maini, Anil K.; Sharma, Ramesh C.

This review has been written to highlight the threat of biological warfare agents, their types and detection. Bacterial biological agent Bacillus anthracis (bacteria causing the disease anthrax) which is most likely to be employed in biological warfare is being discussed in detail. Standoff detection of biological warfare agents in aerosol form using Ultra violet-Laser Induced Fluorescence (UV-LIF) spectroscopy method has been studied. Range-resolved detection and identification of biological aerosols by both nano-second and non-linear femto-second LIDAR is also discussed. Calculated received fluorescence signal for a cloud of typical biological agent Bacillus globigii (Simulants of B. anthracis) at a location of ˜5.0 km at different concentrations in presence of solar background radiation has been described. Overview of current research efforts in internationally available working UV-LIF LIDAR systems are also mentioned briefly.

Commentary: Biochemistry Re-Natured

ERIC Educational Resources Information Center

White, Harold B.

2010-01-01

In his last commentary on "Biochemistry Denatured," this author dealt with his perception that college students today have spent too little of their childhood years playing outside in nature and as a consequence have not learned basic things about the world from personal experience. This "nature-deficit disorder" removes many opportunities for…

Writing throughout the Biochemistry Curriculum: Synergistic Inquiry-Based Writing Projects for Biochemistry Students

ERIC Educational Resources Information Center

Mertz, Pamela; Streu, Craig

2015-01-01

This article describes a synergistic two-semester writing sequence for biochemistry courses. In the first semester, students select a putative protein and are tasked with researching their protein largely through bioinformatics resources. In the second semester, students develop original ideas and present them in the form of a research grant…

Using Pamphlets to Teach Biochemistry: A Service-Learning Project

ERIC Educational Resources Information Center

Harrison, Melinda A.; Dunbar, David; Lopatto, David

2013-01-01

A service-learning project appropriate for a biochemistry or advanced biochemistry course was designed and implemented. The project involved students partnering with a homeless shelter to design informational pamphlets to be displayed at the shelter for the clients' use. The pamphlet topics were based on diseases studied within the course.…

Commentary: Biochemistry and Molecular Biology Educators Launch National Network

ERIC Educational Resources Information Center

Bailey, Cheryl; Bell, Ellis; Johnson, Margaret; Mattos, Carla; Sears, Duane; White, Harold B.

2010-01-01

The American Society of Biochemistry and Molecular Biology (ASBMB) has launched an National Science Foundation (NSF)-funded 5 year project to support biochemistry and molecular biology educators learning what and how students learn. As a part of this initiative, hundreds of life scientists will plan and develop a rich central resource for…

Blog construction as an effective tool in biochemistry active learning.

PubMed

Cubas Rolim, Estêvão; Martins de Oliveira, Julia; Dalvi, Luana T; Moreira, Daniel C; Garcia Caldas, Natasha; Fernandes Lobo, Felipe; André Polli, Démerson; Campos, Élida G; Hermes-Lima, Marcelo

2017-05-01

To boost active learning in undergraduate students, they were given the task of preparing blogs on topics of clinical biochemistry. This "experiment" lasted for 12 teaching-semesters (from 2008 to 2013), and included a survey on the blogs' usefulness at the end of each semester. The survey (applied in the 2008-2010 period) used a Likert-like questionnaire with eight questions and a 1-to-6 scale, from "totally disagree" to "fully agree." Answers of 428 students were analyzed and indicated overall approval of the blog activity: 86% and 35% of the responses scored 4-to-6 and 6, respectively. Considering the survey results, the high grades obtained by students on their blogs (averaging 8.3 in 2008-2010), and the significant increase in average grades of the clinical biochemistry exam after the beginning of the blog system (from 5.5 in 2007 to 6.4 in 2008-2010), we concluded that blogging activity on biochemistry is a promising tool for boosting active learning. © 2016 by The International Union of Biochemistry and Molecular Biology, 45(3):205-215, 2017. © 2016 The International Union of Biochemistry and Molecular Biology.

Biochemistry and biomedicine of quantum dots: from biodetection to bioimaging, drug discovery, diagnostics, and therapy.

PubMed

Yao, Jun; Li, Pingfan; Li, Lin; Yang, Mei

2018-07-01

According to recent research, nanotechnology based on quantum dots (QDs) has been widely applied in the field of bioimaging, drug delivery, and drug analysis. Therefore, it has become one of the major forces driving basic and applied research. The application of nanotechnology in bioimaging has been of concern. Through in vitro labeling, it was found that luminescent QDs possess many properties such as narrow emission, broad UV excitation, bright fluorescence, and high photostability. The QDs also show great potential in whole-body imaging. The QDs can be combined with biomolecules, and hence, they can be used for targeted drug delivery and diagnosis. The characteristics of QDs make them useful for application in pharmacy and pharmacology. This review focuses on various applications of QDs, especially in imaging, drug delivery, pharmaceutical analysis, photothermal therapy, biochips, and targeted surgery. Finally, conclusions are made by providing some critical challenges and a perspective of how this field can be expected to develop in the future. Quantum dots (QDs) is an emerging field of interdisciplinary subject that involves physics, chemistry, materialogy, biology, medicine, and so on. In addition, nanotechnology based on QDs has been applied in depth in biochemistry and biomedicine. Some forward-looking fields emphatically reflected in some extremely vital areas that possess inspiring potential applicable prospects, such as immunoassay, DNA analysis, biological monitoring, drug discovery, in vitro labelling, in vivo imaging, and tumor target are closely connected to human life and health and has been the top and forefront in science and technology to date. Furthermore, this review has not only involved the traditional biochemical detection but also particularly emphasized its potential applications in life science and biomedicine. Copyright © 2018 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Development of vaccines for bio-warfare agents.

PubMed

Rosenthal, S R; Clifford, J C M

2002-01-01

There is a recognized need for the development of new vaccines (as well as other biologicals and drugs) to counteract the effects of a potential bio-terrorist or bio-warfare event in the U.S. domestic population and military forces. Regulation of products to protect against potential bio-warfare agents poses unique challenges since the usual measures of efficacy that require exposure to natural disease may not currently be possible, for epidemiological and ethical reasons. To help to address this issue, the FDA has published and requested comments on a proposed animal rule intended to address certain efficacy issues for new agents for use against lethal or permanently disabling toxic substances. Recent product development activity has focused on Bacillus anthracis (anthrax) and variola major (smallpox), agents that are regarded as highest priority in posing a risk to national security. FDA resources exist to assist vaccine developers with regard to the novel challenges posed in the dinical development of these products.

Computational models of intergroup competition and warfare.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Letendre, Kenneth; Abbott, Robert G.

2011-11-01

This document reports on the research of Kenneth Letendre, the recipient of a Sandia Graduate Research Fellowship at the University of New Mexico. Warfare is an extreme form of intergroup competition in which individuals make extreme sacrifices for the benefit of their nation or other group to which they belong. Among animals, limited, non-lethal competition is the norm. It is not fully understood what factors lead to warfare. We studied the global variation in the frequency of civil conflict among countries of the world, and its positive association with variation in the intensity of infectious disease. We demonstrated that themore » burden of human infectious disease importantly predicts the frequency of civil conflict and tested a causal model for this association based on the parasite-stress theory of sociality. We also investigated the organization of social foraging by colonies of harvester ants in the genus Pogonomyrmex, using both field studies and computer models.« less

Update: Biochemistry of Genetic Manipulation.

ERIC Educational Resources Information Center

Barker, G. R.

1983-01-01

Various topics on the biochemistry of genetic manipulation are discussed. These include genetic transformation and DNA; genetic expression; DNA replication, repair, and mutation; technology of genetic manipulation; and applications of genetic manipulation. Other techniques employed are also considered. (JN)

My Lifelong Passion for Biochemistry and Anaerobic Microorganisms.

PubMed

Thauer, Rudolf Kurt

2015-01-01

Early parental influence led me first to medical school, but after developing a passion for biochemistry and sensing the need for a deeper foundation, I changed to chemistry. During breaks between semesters, I worked in various biochemistry labs to acquire a feeling for the different areas of investigation. The scientific puzzle that fascinated me most was the metabolism of the anaerobic bacterium Clostridium kluyveri, which I took on in 1965 in Karl Decker's lab in Freiburg, Germany. I quickly realized that little was known about the biochemistry of strict anaerobes such as clostridia, methanogens, acetogens, and sulfate-reducing bacteria and that these were ideal model organisms to study fundamental questions of energy conservation, CO2 fixation, and the evolution of metabolic pathways. My passion for anaerobes was born then and is unabated even after 50 years of study.

The Biochemistry of Mitosis

PubMed Central

Wieser, Samuel; Pines, Jonathon

2015-01-01

In this article, we will discuss the biochemistry of mitosis in eukaryotic cells. We will focus on conserved principles that, importantly, are adapted to the biology of the organism. It is vital to bear in mind that the structural requirements for division in a rapidly dividing syncytial Drosophila embryo, for example, are markedly different from those in a unicellular yeast cell. Nevertheless, division in both systems is driven by conserved modules of antagonistic protein kinases and phosphatases, underpinned by ubiquitin-mediated proteolysis, which create molecular switches to drive each stage of division forward. These conserved control modules combine with the self-organizing properties of the subcellular architecture to meet the specific needs of the cell. Our discussion will draw on discoveries in several model systems that have been important in the long history of research on mitosis, and we will try to point out those principles that appear to apply to all cells, compared with those in which the biochemistry has been specifically adapted in a particular organism. PMID:25663668

USAF Cyber Capability Development: A Vision for Future Cyber Warfare & a Concept for Education of Cyberspace Leaders

DTIC Science & Technology

2009-04-01

Significant and interrelated problems are hindering the Air Force’s development of cyber warfare capabilities. The first is a lack of awareness about...why the AF has chosen to take cyber warfare on as a core capability on par with air and space. The second stems from the lack of a commonly...the cyber capabilities needed in the future? The contributions of this research include a strategic vision for future cyber warfare capabilities that

Capability of the People’s Republic of China to Conduct Cyber Warfare and Computer Network Exploitation

DTIC Science & Technology

2009-10-09

Capability of the People’s Republic of China to Conduct Cyber Warfare and Computer Network Exploitation Prepared for The US-China Economic and...the People?s Republic of China to Conduct Cyber Warfare and Computer Network Exploitation 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT...Capability of the People’s Republic of China to Conduct Cyber Warfare and Computer Network Exploitation 2 US-China Economic and Security Review

Teaching Biochemistry to Medical Technology Students.

ERIC Educational Resources Information Center

Gomez-Silva, Benito; And Others

1997-01-01

Describes the biochemistry component of study to become a medical technologist in a Chilean university. Provides details of program structure, course content descriptions, and teaching strategies. (DDR)

Integrating Defense, Diplomacy, and Development (3 D) in the Naval Special Warfare Operator

DTIC Science & Technology

2010-12-01

DIPLOMACY, AND DEVELOPMENT (3 D) IN THE NAVAL SPECIAL WARFARE OPERATOR by William Fiack William Roberts Tim Sulick December 2010...Development (3 D) in the Naval Special Warfare Operator 6. AUTHOR(S) William Fiack, William Roberts, Timothy Sulick 5. FUNDING NUMBERS 7. PERFORMING...MONITORING AGENCY NAME(S) AND ADDRESS(ES) N/A 10. SPONSORING/MONITORING AGENCY REPORT NUMBER 11. SUPPLEMENTARY NOTES The views expressed in

Quality of Life in Iranian Chemical Warfare Veteran's

PubMed Central

Ebadi, Abbas; Moradian, Tayeb; Mollahadi, Mohsen; Saeed, Yaser; Refahi, Ali Akbar

2014-01-01

Background: Mustard gas has different effects on different body systems such as respiratory tract, blood, gastrointestinal, skin, eye, endocrine and peripheral nervous system. Objectives: The purpose of this study was to determine the quality of life in chemical warfare veterans due to sulfur mustard exposure. Patients and Methods: In a cross-sectional and analytic study, 242 patients who had a chemical injury during the Iran-Iraq war (1980-1983) and their lung damage was proven were investigated in our study. The quality of life was measured in these patients using an extensively validated Iranian version of SF-36. Results: The mean age of veterans was 44.12 ± 4.9 ranging from 22 to 62 years. Our results showed that chemical warfare had a decreased quality of life in all subscales of the SF-36. The lowest scores in SF-36 subscales were related to role physical and general health. The data also showed a significant relationship between the number of organs involved and the quality of life in these patients (P < 0.001, r = − 0.33). So that the patients who had more than three organs involved had lower quality of life. 95.4% of our participants experienced another complication with respiratory complication and the ophthalmologic complications were the most frequent accompanying condition. Conclusions: The results imply that chemical warfare survivors suffering from late complications have a low health related quality of life. PMID:25031863

New Developments in Chinese Strategic Psychological Warfare

DTIC Science & Technology

2005-01-01

Taoism , which coupled hardness with softness in warfare, was not the only influence on the theory of psychological operations in ancient China. Other...portraying Islamic martyrs who appear to speak to soldiers from the clouds.38 In contemporary wars, such as the Gulf War, the first targets attacked have

Optimal Learning for Efficient Experimentation in Nanotechnology and Biochemistry

DTIC Science & Technology

2015-12-22

AFRL-AFOSR-VA-TR-2016-0018 Optimal Learning for Efficient Experimentation in Nanotechnology , Biochemistry Warren Powell TRUSTEES OF PRINCETON...3. DATES COVERED (From - To) 01-07-2012 to 30-09-2015 4. TITLE AND SUBTITLE Optimal Learning for Efficient Experimentation in Nanotechnology and...in Nanotechnology and Biochemistry Principal Investigators: Warren B. Powell Princeton University Department of Operations Research and

Medical biochemistry in Macedonia: a profession for physicians and natural scientists.

PubMed

Traikovska, S; Dzhekova-Stojkova, S

2001-06-01

Medical biochemistry or clinical chemistry in its roots is an interdisciplinary science between natural sciences and medicine. The largest part of medical biochemistry is natural science (chemistry, biochemistry, biology, physics, mathematics), which is very well integrated in deduction of medical problems. Medical biochemistry throughout the world, including Macedonia, should be a professional field open to both physicians and natural scientists, according to its historical development, theoretical characteristics and applied practice. Physicians and natural scientists follow the same route in clinical chemistry during the postgraduate training of specialization in medical biochemistry/clinical chemistry. However, in Macedonia the specialization in medical biochemistry/clinical chemistry is today regulated by law only for physicians and pharmacists. The study of clinical chemistry in Europe has shown its interdisciplinary character. In most European countries different professions, such as physicians, chemists/biochemists, pharmacists, biologists and others could specialize in clinical chemistry. The question for the next generation of specialists in Macedonia is whether to accept the present conditions or to attempt to change the law to include chemists/biochemists and biologists as well. The latter used to be a practice in Macedonia 20 years ago, and still is in many European countries. Such change in law would also result in changes in the postgraduate educational program in medical biochemistry in Macedonia. The new postgraduate program has to follow the European Syllabus, recommended by EC4. To obtain sufficient knowledge in clinical chemistry, the duration of vocational training (undergraduate and postgraduate) for all trainees (physicians, pharmaceutics, chemists/biochemists and biologists) should be 8 years.

Situation Awareness Information Dominance & Information Warfare.

DTIC Science & Technology

1997-02-01

Information warfare and its primary objective of achieving information dominance over enemy forces have arisen as a major area of emphasis for future...military actions. The concept of information dominance and the issues involved in attaining it are explored through a model of situation awareness...directions for the development of systems to support the goal of information dominance can be established.

Defining Islamic Way of Warfare and Its Comparison with Al Qaeda Doctrine

DTIC Science & Technology

2012-06-08

DEFINING ISLAMIC WAY OF WARFARE AND ITS COMPARISON WITH AL QAEDA DOCTRINE A thesis presented to the Faculty of the U.S. Army...subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO...Islamic way of warfare. It is important to understand that anything, to be qualified as Islamic, has to have a reference from the core sources of Islam

Detection of biological warfare agents using ultra violet-laser induced fluorescence LIDAR.

PubMed

Joshi, Deepti; Kumar, Deepak; Maini, Anil K; Sharma, Ramesh C

2013-08-01

This review has been written to highlight the threat of biological warfare agents, their types and detection. Bacterial biological agent Bacillus anthracis (bacteria causing the disease anthrax) which is most likely to be employed in biological warfare is being discussed in detail. Standoff detection of biological warfare agents in aerosol form using Ultra violet-Laser Induced Fluorescence (UV-LIF) spectroscopy method has been studied. Range-resolved detection and identification of biological aerosols by both nano-second and non-linear femto-second LIDAR is also discussed. Calculated received fluorescence signal for a cloud of typical biological agent Bacillus globigii (Simulants of B. anthracis) at a location of ~5.0 km at different concentrations in presence of solar background radiation has been described. Overview of current research efforts in internationally available working UV-LIF LIDAR systems are also mentioned briefly. Copyright © 2013 Elsevier B.V. All rights reserved.

Emerging Roles of Combat Communication Squadrons in Cyber Warfare as Related to Computer Network Attack, Defense and Exploitation

DTIC Science & Technology

2011-06-01

EMERGING ROLES OF COMBAT COMMUNICATION SQUADRONS IN CYBER WARFARE AS RELATED TO COMPUTER NETWORK ATTACK, DEFENSE AND EXPLOITATION GRADUATE RESEARCH...Communication Squadrons in Cyber Warfare as Related to Computer Network Attack, Defense and Exploitation GRADUATE RESEARCH PROJECT Presented to the Faculty...Education and Training Command In Partial Fulfillment of the Requirements for the Degree of Master of Cyber Warfare Michael J. Myers Major, USAF June 2011

IMS software developments for the detection of chemical warfare agent

NASA Technical Reports Server (NTRS)

Klepel, ST.; Graefenhain, U.; Lippe, R.; Stach, J.; Starrock, V.

1995-01-01

Interference compounds like gasoline, diesel, burning wood or fuel, etc. are presented in common battlefield situations. These compounds can cause detectors to respond as a false positive or interfere with the detector's ability to respond to target compounds such as chemical warfare agents. To ensure proper response of the ion mobility spectrometer to chemical warfare agents, two special software packages were developed and incorporated into the Bruker RAID-1. The programs suppress interferring signals caused by car exhaust or smoke gases resulting from burning materials and correct the influence of variable sample gas humidity which is important for detection and quantification of blister agents like mustard gas or lewisite.

A National Comparison of Biochemistry and Molecular Biology Capstone Experiences

ERIC Educational Resources Information Center

Aguanno, Ann; Mertz, Pamela; Martin, Debra; Bell, Ellis

2015-01-01

Recognizing the increasingly integrative nature of the molecular life sciences, the "American Society for Biochemistry and Molecular Biology" (ASBMB) recommends that Biochemistry and Molecular Biology (BMB) programs develop curricula based on concepts, content, topics, and expected student outcomes, rather than courses. To that end,…

The Age of Irregular Warfare: So What?

DTIC Science & Technology

2010-01-01

Lynne Rienner, 2002), and Michael Vlahos , Fighting Identity: Sacred War and World Change (Westport, CT: Praeger Security Interna- tional, 2009). 7...the forms that warfare will take.” 8 I agree with Michael Vlahos that we poten- tially make matters worse by using the image of a triangle to depict

Clinical biochemistry education in Spain.

PubMed

Queraltó, J M

1994-12-31

Clinical biochemistry in Spain was first established in 1978 as an independent specialty. It is one of several clinical laboratory sciences specialties, together with haematology, microbiology, immunology and general laboratory (Clinical analysis, análisis clinicos). Graduates in Medicine, Pharmacy, Chemistry and Biological Sciences can enter post-graduate training in Clinical Chemistry after a nation-wide examination. Training in an accredited Clinical Chemistry department is 4 years. A national committee for medical and pharmacist specialties advises the government on the number of trainees, program and educational units accreditation criteria. Technical staff includes nurses and specifically trained technologists. Accreditation of laboratories is developed at different regional levels. The Spanish Society for Clinical Biochemistry and Molecular Pathology (SECQ), the national representative in the IFCC, has 1600 members, currently publishes a scientific journal (Química Clinica) and a newsletter. It organizes a continuous education program, a quality control program and an annual Congress.

Military Engineers and Chemical Warfare Troops (Inzhenernye Voiska Khimicheskie Voiska),

DTIC Science & Technology

MILITARY FORCES(FOREIGN), *MILITARY ORGANIZATIONS, MILITARY ENGINEERING , INFANTRY, AMPHIBIOUS OPERATIONS, MINELAYING, ARMORED VEHICLES, NUCLEAR...RADIATION, DOSIMETERS, CHEMICAL WARFARE, PROTECTIVE CLOTHING, DECONTAMINATION, HEALTH PHYSICS.

Unorthodox Thoughts about Asymmetric Warfare

DTIC Science & Technology

2003-01-01

Unorthodox Thoughts about Asymmetric Warfare MONTGOMERY C. MEIGS “Bad terminology is the enemy of good thinking.” — Warren Buffett 1 I n the last few...Mr. Buffett , the Sage of Omaha, and agree on a set of definitions that will provide our tools for analysis. In preempting the terrorist are we really...still apt. 10. Warren Bennis and Burt Nanus, Leaders (New York: HarperCollins, 1997), pp. 102-40. Bennis and Nanus provide a useful construct for

Information Warfare and International Law

DTIC Science & Technology

1998-01-01

OMB control number. 1. REPORT DATE 1998 2. REPORT TYPE 3. DATES COVERED 00-00-1998 to 00-00-1998 4. TITLE AND SUBTITLE Information Warfare and...international law where those dictates endanger or conflict with the pursuit of their fundamental interests , including national security. The Legal...34war," and may not be covered by the humanitarian provisions that attempt to lessen war’s cruelty.28 FIGURE 3 The Purpose of This Book The

Modeling Anti-Air Warfare With Discrete Event Simulation and Analyzing Naval Convoy Operations

DTIC Science & Technology

2016-06-01

WARFARE WITH DISCRETE EVENT SIMULATION AND ANALYZING NAVAL CONVOY OPERATIONS by Ali E. Opcin June 2016 Thesis Advisor: Arnold H. Buss Co...REPORT DATE June 2016 3. REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE MODELING ANTI-AIR WARFARE WITH DISCRETE EVENT...In this study, a discrete event simulation (DES) was built by modeling ships, and their sensors and weapons, to simulate convoy operations under

Glycobiology, How to Sugar-Coat an Undergraduate Advanced Biochemistry Laboratory

ERIC Educational Resources Information Center

McReynolds, Katherine D.

2006-01-01

A second semester biochemistry laboratory has been implemented as an independent projects course at California State University, Sacramento since 1999. To incorporate aspects of carbohydrate biochemistry, or glycobiology, into our curriculum, projects in lectin isolation and purification were undertaken over the course of two semesters. Through…

A 13-week research-based biochemistry laboratory curriculum.

PubMed

Lefurgy, Scott T; Mundorff, Emily C

2017-09-01

Here, we present a 13-week research-based biochemistry laboratory curriculum designed to provide the students with the experience of engaging in original research while introducing foundational biochemistry laboratory techniques. The laboratory experience has been developed around the directed evolution of an enzyme chosen by the instructor, with mutations designed by the students. Ideal enzymes for this curriculum are able to be structurally modeled, solubly expressed, and monitored for activity by UV/Vis spectroscopy, and an example curriculum for haloalkane dehalogenase is given. Unique to this curriculum is a successful implementation of saturation mutagenesis and high-throughput screening of enzyme function, along with bioinformatics analysis, homology modeling, structural analysis, protein expression and purification, polyacrylamide gel electrophoresis, UV/Vis spectroscopy, and enzyme kinetics. Each of these techniques is carried out using a novel student-designed mutant library or enzyme variant unique to the lab team and, importantly, not described previously in the literature. Use of a well-established set of protocols promotes student data quality. Publication may result from the original student-generated hypotheses and data, either from the class as a whole or individual students that continue their independent projects upon course completion. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(5):437-448, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

An evolutionary theory of large-scale human warfare: Group-structured cultural selection.

PubMed

Zefferman, Matthew R; Mathew, Sarah

2015-01-01

When humans wage war, it is not unusual for battlefields to be strewn with dead warriors. These warriors typically were men in their reproductive prime who, had they not died in battle, might have gone on to father more children. Typically, they are also genetically unrelated to one another. We know of no other animal species in which reproductively capable, genetically unrelated individuals risk their lives in this manner. Because the immense private costs borne by individual warriors create benefits that are shared widely by others in their group, warfare is a stark evolutionary puzzle that is difficult to explain. Although several scholars have posited models of the evolution of human warfare, these models do not adequately explain how humans solve the problem of collective action in warfare at the evolutionarily novel scale of hundreds of genetically unrelated individuals. We propose that group-structured cultural selection explains this phenomenon. © 2015 Wiley Periodicals, Inc.

Changing the Scale and Efficiency of Chemical Warfare Countermeasure Discovery Using the Zebrafish

PubMed Central

Peterson, Randall T.; MacRae, Calum A.

2013-01-01

As the scope of potential chemical warfare agents grows rapidly and as the diversity of potential threat scenarios expands with non-state actors, so a need for innovative approaches to countermeasure development has emerged. In the last few years, the utility of the zebrafish as a model organism that is amenable to high-throughput screening has become apparent and this system has been applied to the unbiased discovery of chemical warfare countermeasures. This review summarizes the in vivo screening approach that has been pioneered in the countermeasure discovery arena, and highlights the successes to date as well as the potential challenges in moving the field forward. Importantly, the establishment of a zebrafish platform for countermeasure discovery would offer a rapid response system for the development of antidotes to the continuous stream of new potential chemical warfare agents. PMID:24273586

Biological Warfare at the 1346 Siege of Caffa

PubMed Central

2002-01-01

On the basis of a 14th-century account by the Genoese Gabriele de’ Mussi, the Black Death is widely believed to have reached Europe from the Crimea as the result of a biological warfare attack. This is not only of great historical interest but also relevant to current efforts to evaluate the threat of military or terrorist use of biological weapons. Based on published translations of the de’ Mussi manuscript, other 14th-century accounts of the Black Death, and secondary scholarly literature, I conclude that the claim that biological warfare was used at Caffa is plausible and provides the best explanation of the entry of plague into the city. This theory is consistent with the technology of the times and with contemporary notions of disease causation; however, the entry of plague into Europe from the Crimea likely occurred independent of this event. PMID:12194776

Electronic warfare microwave components

NASA Astrophysics Data System (ADS)

Cosby, L. A.

1984-09-01

The current and projected state-of-the-art for electronic warfare (EW) microwave components is reviewed, with attention given to microwave components used extensively in EW systems for reconnaissance, threat warning, direction finding, and repeater jamming. It is emphasized that distributed EW systems must be able to operate from manned tactical and strategic platforms, with requirements including remote aerospace and space elements, as well as the need for expandable devices for detection, location, and denial/deception functions. EW coordination, or battle management, across a distributed system is a rapidly emerging requirement that must be integrated into current and projected command-and-control programs.

The use of multiple tools for teaching medical biochemistry.

PubMed

Sé, Alexandre B; Passos, Renato M; Ono, André H; Hermes-Lima, Marcelo

2008-03-01

In this work, we describe the use of several strategies employing the philosophies of active learning and problem-based learning (PBL) that may be used to improve the teaching of metabolic biochemistry to medical and nutritional undergraduate students. The main activities are as follows: 1) a seminar/poster system in a mini-congress format (using topics of applied biochemistry); 2) a true/false applied biochemistry exam (written by peer tutors); 3) a 9-h exam on metabolism (based in real publications); 4) the Advanced Biochemistry course (directed to peer tutors, where students learn how to read and criticize real medical papers); 5) experiments about nutrition and metabolism, using students as volunteers, and about free radicals (real science for students); 6) the BioBio blog (taking advantage of the "web age," this enhances out of class exchanges of information between the professor, students, and peer tutors); 7) student lectures on public health issues and metabolic disorders directed to the community and lay people; and 8) the BioBio quiz show. The main objective of these activities is to provide students with a more practical and interesting approach to biochemistry, such as the application of theoretical knowledge to real situations (diseases, experiments, media information, and scientific discoveries). In addition, we emphasize the importance of peer tutor activities for optimized learning of both students and peer tutors, the importance of a closer interaction between students and teaching staff, and the necessity to initiate students precociously in two broad fields of medical activity: "real" basic science and contact with the public (also helping students--future doctors and nutritionists--to be able to communicate with lay people). Most activities were evaluated by the students through written questionnaires and informal conversations, along various semesters, indicating good acceptance and approval of these methods. Good student scores in the

Concept mapping enhances learning of biochemistry.

PubMed

Surapaneni, Krishna M; Tekian, Ara

2013-03-05

Teaching basic science courses is challenging in undergraduate medical education because of the ubiquitous use of didactic lectures and reward for recall of factual information during examinations. The purpose of this study is to introduce concept maps with clinical cases (the innovative program) to improve learning of biochemistry course content. Participants were first year medical students (n=150) from Saveetha Medical College and Hospital (India); they were randomly divided into two groups of 75, one group attending the traditional program, the other the innovative program. Student performance was measured using three written knowledge tests (each with a maximum score of 20). The students also evaluated the relevance of the learning process using a 12-item questionnaire. Students in the innovative program using concept mapping outperformed those in the traditional didactic program (means of 7.13-8.28 vs. 12.33-13.93, p<0.001). The students gave high positive ratings for the innovative course (93-100% agreement). The new concept-mapping program resulted in higher academic performance compared to the traditional course and was perceived favorably by the students. They especially valued the use of concept mapping as learning tools to foster the relevance of biochemistry to clinical practice, and to enhance their reasoning and learning skills, as well as their deeper understanding for biochemistry.

Concept mapping enhances learning of biochemistry

PubMed Central

Surapaneni, Krishna M.; Tekian, Ara

2013-01-01

Background Teaching basic science courses is challenging in undergraduate medical education because of the ubiquitous use of didactic lectures and reward for recall of factual information during examinations. The purpose of this study is to introduce concept maps with clinical cases (the innovative program) to improve learning of biochemistry course content. Methods Participants were first year medical students (n=150) from Saveetha Medical College and Hospital (India); they were randomly divided into two groups of 75, one group attending the traditional program, the other the innovative program. Student performance was measured using three written knowledge tests (each with a maximum score of 20). The students also evaluated the relevance of the learning process using a 12-item questionnaire. Results Students in the innovative program using concept mapping outperformed those in the traditional didactic program (means of 7.13–8.28 vs. 12.33–13.93, p<0.001). The students gave high positive ratings for the innovative course (93–100% agreement). Conclusion The new concept-mapping program resulted in higher academic performance compared to the traditional course and was perceived favorably by the students. They especially valued the use of concept mapping as learning tools to foster the relevance of biochemistry to clinical practice, and to enhance their reasoning and learning skills, as well as their deeper understanding for biochemistry. PMID:23464600

Concept mapping enhances learning of biochemistry.

PubMed

Surapaneni, KrishnaM; Tekian, Ara

2013-01-01

Teaching basic science courses is challenging in undergraduate medical education because of the ubiquitous use of didactic lectures and reward for recall of factual information during examinations. The purpose of this study is to introduce concept maps with clinical cases (the innovative program) to improve learning of biochemistry course content. Participants were first year medical students (n=150) from Saveetha Medical College and Hospital (India); they were randomly divided into two groups of 75, one group attending the traditional program, the other the innovative program. Student performance was measured using three written knowledge tests (each with a maximum score of 20). The students also evaluated the relevance of the learning process using a 12-item questionnaire. Students in the innovative program using concept mapping outperformed those in the traditional didactic program (means of 7.13-8.28 vs. 12.33-13.93, p<0.001). The students gave high positive ratings for the innovative course (93-100% agreement). The new concept-mapping program resulted in higher academic performance compared to the traditional course and was perceived favorably by the students. They especially valued the use of concept mapping as learning tools to foster the relevance of biochemistry to clinical practice, and to enhance their reasoning and learning skills, as well as their deeper understanding for biochemistry.

Blended Learning in Biochemistry Education: Analysis of Medical Students' Perceptions

ERIC Educational Resources Information Center

Wardenski, Rosilaine de Fatima; de Espindola, Marina Bazzo; Struchiner, Miriam; Giannella, Tais Rabetti

2012-01-01

The objective of this study was to analyze first-year UFRJ medical students' perceptions about the implementation of a blended learning (BL) experience in their Biochemistry I course. During the first semester of 2009, three Biochemistry professors used the Constructore course management system to develop virtual learning environments (VLEs) for…

Circular Dichroism Spectroscopy: Enhancing a Traditional Undergraduate Biochemistry Laboratory Experience

ERIC Educational Resources Information Center

Lewis, Russell L.; Seal, Erin L.; Lorts, Aimee R.; Stewart, Amanda L.

2017-01-01

The undergraduate biochemistry laboratory curriculum is designed to provide students with experience in protein isolation and purification protocols as well as various data analysis techniques, which enhance the biochemistry lecture course and give students a broad range of tools upon which to build in graduate level laboratories or once they…

Known structure, unknown function: An inquiry-based undergraduate biochemistry laboratory course.

PubMed

Gray, Cynthia; Price, Carol W; Lee, Christopher T; Dewald, Alison H; Cline, Matthew A; McAnany, Charles E; Columbus, Linda; Mura, Cameron

2015-01-01

Undergraduate biochemistry laboratory courses often do not provide students with an authentic research experience, particularly when the express purpose of the laboratory is purely instructional. However, an instructional laboratory course that is inquiry- and research-based could simultaneously impart scientific knowledge and foster a student's research expertise and confidence. We have developed a year-long undergraduate biochemistry laboratory curriculum wherein students determine, via experiment and computation, the function of a protein of known three-dimensional structure. The first half of the course is inquiry-based and modular in design; students learn general biochemical techniques while gaining preparation for research experiments in the second semester. Having learned standard biochemical methods in the first semester, students independently pursue their own (original) research projects in the second semester. This new curriculum has yielded an improvement in student performance and confidence as assessed by various metrics. To disseminate teaching resources to students and instructors alike, a freely accessible Biochemistry Laboratory Education resource is available at http://biochemlab.org. © 2015 The Authors Biochemistry and Molecular Biology Education published by Wiley Periodicals, Inc. on behalf of International Union of Biochemistry and Molecular Biology.

Known structure, unknown function: An inquiry‐based undergraduate biochemistry laboratory course

PubMed Central

Gray, Cynthia; Price, Carol W.; Lee, Christopher T.; Dewald, Alison H.; Cline, Matthew A.; McAnany, Charles E.

2015-01-01

Abstract Undergraduate biochemistry laboratory courses often do not provide students with an authentic research experience, particularly when the express purpose of the laboratory is purely instructional. However, an instructional laboratory course that is inquiry‐ and research‐based could simultaneously impart scientific knowledge and foster a student's research expertise and confidence. We have developed a year‐long undergraduate biochemistry laboratory curriculum wherein students determine, via experiment and computation, the function of a protein of known three‐dimensional structure. The first half of the course is inquiry‐based and modular in design; students learn general biochemical techniques while gaining preparation for research experiments in the second semester. Having learned standard biochemical methods in the first semester, students independently pursue their own (original) research projects in the second semester. This new curriculum has yielded an improvement in student performance and confidence as assessed by various metrics. To disseminate teaching resources to students and instructors alike, a freely accessible Biochemistry Laboratory Education resource is available at http://biochemlab.org. © 2015 The Authors Biochemistry and Molecular Biology Education published by Wiley Periodicals, Inc. on behalf of International Union of Biochemistry and Molecular Biology, 43(4):245–262, 2015. PMID:26148241

Biochemistry students' ideas about shape and charge in enzyme-substrate interactions.

PubMed

Linenberger, Kimberly J; Bretz, Stacey Lowery

2014-01-01

Biochemistry is a visual discipline that requires students to develop an understanding of numerous representations. However, there is very little known about what students actually understand about the representations that are used to communicate ideas in biochemistry. This study investigated biochemistry students' understanding of multiple representations of enzyme-substrate interactions through both student interviews (N = 25) and responses by a national sample (N = 707) to the Enzyme-Substrate Interactions Concept Inventory. This manuscript reports the findings regarding one category of misconceptions measured by the concept inventory, namely, students' understandings of shape and charge in the context of enzyme-substrate interactions. Students interpret molecular representations depicting such interactions by determining the complementarity between enzyme and substrate by focusing upon charge and hydrogen bonding, but with a disregard for stereochemistry. Copyright © 2014 by The International Union of Biochemistry and Molecular Biology.

Jmol-Enhanced Biochemistry Research Projects

ERIC Educational Resources Information Center

Saderholm, Matthew; Reynolds, Anthony

2011-01-01

We developed a protein research project for a one-semester biochemistry lecture class to enhance learning and more effectively train students to understand protein structure and function. During this semester-long process, students select a protein with known structure and then research its structure, sequence, and function. This project…

Soil Microbiology, Ecology, and Biochemistry

USDA-ARS?s Scientific Manuscript database

The 4th edition of Soil Microbiology, Ecology, and Biochemistry Edited by Eldor Paul continues in the vein of the 3rd edition by providing an excellent, broad-reaching introduction to soil biology. The new edition improves on the previous by providing extensive supplementary materials, links to outs...

United States Coast Guard Antisubmarine Warfare (ASW) in the Maritime Defense Zone (MDZ) - A Strategic Approach

DTIC Science & Technology

1989-03-01

RIC ILE COPY AIR WAR COLLGE REEAC R~pCR UNITED STATES COAST GUARD ANTISUBMARINE WARFARE (ASW) IN THE MARITIME DEFENSE ZONE (MDZ) -A STRATEGIC...going to perform in these MDZs. Those tasks identified so far include: port and coastal physical security & preventive safety, mine warfare

Irregular Warfare Centric Foreign Internal Defense

DTIC Science & Technology

2013-06-01

goods, its weak security forces and the gap unfilled by international forces.126 Scott Mann conducted a video interview on October 3 , 2012 and...Reduction Project (0704–0188) Washington DC 20503. 1. AGENCY USE ONLY (Leave blank) 2. REPORT DATE June 2013 3 . REPORT TYPE AND DATES COVERED...DISTRIBUTION CODE A 13. ABSTRACT (maximum 200 words) Conflict over the past few decades has changed drastically. Warfare changed with the conflict

Interagency Cooperation for Irregular Warfare at the Combatant Command

DTIC Science & Technology

2009-01-01

Directorate, and the USSOCOM Interagency Task Force ( IATF ) offer examples of JIACGs coping with the issues of IW. Each organization possesses strengths...46 USSOCOM IATF History...Force for Irregular Warfare ( IATF IW).33 EUCOM conducts interagency

A history of biological and chemical warfare and terrorism.

PubMed

Malloy, C D

2000-07-01

This article provides a brief history of biological warfare and terrorism. It contends that examining disease in history provides public health specialists with the knowledge necessary to improve our surveillance system for potential acts of bioterrorism.

War-Gaming Network-Centric Warfare

DTIC Science & Technology

2001-01-01

games as well. 6 2 N A V A L W A R C O L L E G E R E V I E W War games are also classified...traditional gaming . All war games , whether they involve fighting sail R U B E L 6 3 Until a tactical network of units, each of them exercising a great degree... gaming and simulation. R U B E L 6 5 The principal requirements for achieving network-centric warfare are a network and shared awareness. By a

[Perspectives in the treatments of poisonings by organophosphorus insecticides and warfare nerve agents].

PubMed

Sogorb-Sánchez, M A; Vilanova-Gisbert, E; Carrera-González, V

Organophosphorus compounds are worldwide employed as insecticides and are yearly responsible of several millions of poisonings. The chemical structure of most of the warfare nerve agents also corresponds with an organophosphorus compound. Organophosphorus insecticides and warfare nerve agents exert their main toxicological effects through inhibition of acetylcholinesterase. Current treatments of patients poisoned with organophosphorus compounds include atropine (in order to protect muscarinic receptors), oximes (in order to accelerate the reactivation of the inhibited acetylcholinesterase) and benzodiazepines (in order to avoid convulsions). The administration of phosphotriesterases (enzymes involved in the detoxication of organophosphorus compounds through hydrolysis) is a very effective treatment against poisonings by organophosphorus insecticides and warfare nerve agents. There are experimental preventive treatments based on the simultaneous administration of carbamates and certain antimuscarinic drugs, different from atropine, which notably improve the efficacy of the classical treatments applied after poisonings by warfare nerve agents. The treatments based in the administration of phosphotriesterases might be the response to the call of the World Health Organization for searching new treatments with capability to reduce the high mortality recorded in the cases of poisonings by organophosphorus compounds. These treatments can be applied in a preventive way without the intrinsic neurotoxicity associated to the preventive treatments based on carbamates and antimuscarinic drugs. Therefore, these treatments are specially interesting for people susceptible to suffer severe exposures, i.e. sprayers in the farms.

Assessment of learning gains in a flipped biochemistry classroom.

PubMed

Ojennus, Deanna Dahlke

2016-01-01

The flipped classroom has become an increasingly popular pedagogical approach to teaching and learning. In this study, learning gains were assessed in a flipped biochemistry course and compared to gains in a traditional lecture. Although measured learning gains were not significantly different between the two courses, student perception of learning gains did differ and indicates a higher level of satisfaction with the flipped lecture format. © 2015 The International Union of Biochemistry and Molecular Biology.

Oxygen-Free Biochemistry: The Putative CHN Foundation for Exotic Life in a Hydrocarbon World?

PubMed

Lv, Kong-Peng; Norman, Lucy; Li, Yi-Liang

2017-11-01

Since Earth's biochemistry is carbon-based and water-borne, the main strategies for searching for life elsewhere are "follow the carbon" and "follow the water." Recently, however, there is a growing focus on the prospect that putative exotic life on other planets could rely on unearthly biochemistries. Here, we hypothesize a novel oxygen-free organic chemistry for supporting potential exotic biosystems, which is named CHN biochemistry. This oxygen-free CHN biochemistry starts from simple oxygen-free species (including hydrocarbons, hydrogen cyanide, and nitriles) and produces a range of functional macromolecules that may function in similar ways to terran macromolecules, such as sugars (cyanosugars), acids (cyanoacids), amino acids (amino cyanoacids), and nucleobases (cyanonucleobases). These CHN macromolecules could further interact with each other to generate higher "cyanoester" and "cyanoprotein" systems. In addition, theoretical calculations indicate that the energy changes of some reactions are consistent with their counterparts in Earth's biochemistry. The CHN biochemistry-based life would be applicable in habitats with a low bioavailability of oxygen, such as the alkane lakes of Titan and non-aquatic liquids on extrasolar bodies. Key Words: Oxygen-free biochemistry-Titan-Hydrocarbons-Hydrogen cyanide-Nitriles. Astrobiology 17, 1173-1181.

Identifying Opportunities for Vertical Integration of Biochemistry and Clinical Medicine.

PubMed

Wendelberger, Karen J.; Burke, Rebecca; Haas, Arthur L.; Harenwattananon, Marisa; Simpson, Deborah

1998-01-01

Objectives: Retention of basic science knowledge, as judged by National Board of Medical Examiners' (NBME) data, suffers due to lack of apparent relevance and isolation of instruction from clinical application, especially in biochemistry. However, the literature reveals no systematic process for identifying key biochemical concepts and associated clinical conditions. This study systematically identified difficult biochemical concepts and their common clinical conditions as a critical step towards enhancing relevance and retention of biochemistry.Methods: A multi-step/ multiple stakeholder process was used to: (1) identify important biochemistry concepts; (2) determine students' perceptions of concept difficulty; (3) assess biochemistry faculty, student, and clinical teaching scholars' perceived relevance of identified concepts; and (4) identify associated common clinical conditions for relevant and difficult concepts. Surveys and a modified Delphi process were used to gather data, subsequently analyzed using SPSS for Windows.Results: Sixteen key biochemical concepts were identified. Second year medical students rated 14/16 concepts as extremely difficult while fourth year students rated nine concepts as moderately to extremely difficult. On average, each teaching scholar generated common clinical conditions for 6.2 of the 16 concepts, yielding a set of seven critical concepts and associated clinical conditions.Conclusions: Key stakeholders in the instructional process struggle to identify biochemistry concepts that are critical, difficult to learn and associated with common clinical conditions. However, through a systematic process beginning with identification of concepts and associated clinical conditions, relevance of basic science instruction can be enhanced.

IW Cyberlaw. The Legal Issues of Information Warfare

DTIC Science & Technology

1999-01-01

actions. The Information Warfare Center at Kelly AFB, Texas, casts a wide net in its definition of information war- fare. Its view is that... Maura T. McGowan, in an unpublished study en- titled “Law of Armed Conflict” (Colorado Springs, Colo.: United States Air Force Academy, Department of

Foundational concepts and underlying theories for majors in "biochemistry and molecular biology".

PubMed

Tansey, John T; Baird, Teaster; Cox, Michael M; Fox, Kristin M; Knight, Jennifer; Sears, Duane; Bell, Ellis

2013-01-01

Over the past two years, through an NSF RCN UBE grant, the ASBMB has held regional workshops for faculty members and science educators from around the country that focused on identifying: 1) core principles of biochemistry and molecular biology, 2) essential concepts and underlying theories from physics, chemistry, and mathematics, and 3) foundational skills that undergraduate majors in biochemistry and molecular biology must understand to complete their major coursework. Using information gained from these workshops, as well as from the ASBMB accreditation working group and the NSF Vision and Change report, the Core Concepts working group has developed a consensus list of learning outcomes and objectives based on five foundational concepts (evolution, matter and energy transformation, homeostasis, information flow, and macromolecular structure and function) that represent the expected conceptual knowledge base for undergraduate degrees in biochemistry and molecular biology. This consensus will aid biochemistry and molecular biology educators in the development of assessment tools for the new ASBMB recommended curriculum. © 2013 by The International Union of Biochemistry and Molecular Biology.

The concept lens diagram: a new mechanism for presenting biochemistry content in terms of "big ideas".

PubMed

Rowland, Susan L; Smith, Christopher A; Gillam, Elizabeth M A; Wright, Tony

2011-07-01

A strong, recent movement in tertiary education is the development of conceptual, or "big idea" teaching. The emphasis in course design is now on promoting key understandings, core competencies, and an understanding of connections between different fields. In biochemistry teaching, this radical shift from the content-based tradition is being driven by the "omics" information explosion; we can no longer teach all the information we have available. Biochemistry is a core, enabling discipline for much of modern scientific research, and biochemistry teaching is in urgent need of a method for delivery of conceptual frameworks. In this project, we aimed to define the key concepts in biochemistry. We find that the key concepts we defined map well onto the core science concepts recommended by the Vision and Change project. We developed a new method to present biochemistry through the lenses of these concepts. This new method challenged the way we thought about biochemistry as teachers. It also stimulated the majority of the students to think more deeply about biochemistry and to make links between biochemistry and material in other courses. This method is applicable to the full spectrum of content usually taught in biochemistry. Copyright © 2011 Wiley Periodicals, Inc.

Serum biochemistry and morbidity among runners presenting for medical care after an Australian mountain ultramarathon.

PubMed

Reid, Stephen A; King, M Jonathan

2007-07-01

To determine if exercise-associated hyponatremia (EAH) was a cause of morbidity among runners requiring medical care at an Australian mountain ultramarathon. Case series. Six Foot Track mountain ultramarathon, New South Wales, Australia, March 2006. Runners presenting to the medical facility. Serum biochemistry. No cases of exercise-associated hyponatremia were identified among 9 athletes (from 775 starters) who were treated with intravenous fluid therapy. Unwell runners had a mean serum (Na) of 143 mmol/L (range 138-147 mmol/L). All runners tested had elevated serum urea and creatinine concentrations. In this setting, EAH was not a significant cause of morbidity.

Biochemistry Students' Ideas about How an Enzyme Interacts with a Substrate

ERIC Educational Resources Information Center

Linenberger, Kimberly J.; Bretz, Stacey Lowery

2015-01-01

Enzyme-substrate interactions are a fundamental concept of biochemistry that is built upon throughout multiple biochemistry courses. Central to understanding enzyme-substrate interactions is specific knowledge of exactly how an enzyme and substrate interact. Within this narrower topic, students must understand the various binding sites on an…

Military medicine and the ethics of war: British colonial warfare during the Seven Years War (1756-63).

PubMed

Charters, Erica

2010-01-01

This article examines 18th-century European warfare, tracing the first formal codifications of conventions of war, frequently introduced by military physicians and initially regarding the treatment of the sick and wounded. It outlines to what extent these conventions were followed in practice, particularly in the challenging environment of American irregular warfare, with a focus on the most well-known incident of "biological warfare" in the period: the deliberate spread of smallpox by British officers among Amerindians in 1763. More broadly, it demonstrates that the history of military medicine provides a fruitful method with which to uncover assumptions about the ethics of war.

Simulated experiment for elimination of chemical and biological warfare agents by making use of microwave plasma torch

NASA Astrophysics Data System (ADS)

Hong, Yong C.; Kim, Jeong H.; Uhm, Han S.

2004-02-01

The threat of chemical and biological warfare agents in a domestic terrorist attack and in military conflict is increasing worldwide. Elimination and decontamination of chemical and biological warfare (CBW) agents are immediately required after such an attack. Simulated experiment for elimination of CBW agents by making use of atmospheric-pressure microwave plasma torches is carried out. Elimination of biological warfare agents indicated by the vitrification or burnout of sewage sludge powders and decomposition of toluene gas as a chemical agent stimulant are presented. A detailed characterization for the elimination of the simulant chemicals using Fourier transform infrared and gas chromatography is also presented.

Reflections on my career in analytical chemistry and biochemistry

PubMed Central

SWEELEY, Charles C.

2010-01-01

My career has been focused in two major areas, analytical chemistry and biochemistry of complex lipids and glycoconjugates. Included here are the pioneering work on the gas chromatography of long-chain sphingolipid bases, carbohydrates, steroids and urinary organic acids. Mass spectrometry was utilized extensively in structural studies of sphingolipids, fatty acids, carbohydrates, steroids, urinary organic acids, polyisoprenoid alcohols, and juvenile hormone. Computer systems were developed for the acquisition and analysis of mass spectra, and were used for development of automated metabolic profiling of complex mixtures of metabolites. Fabry’s disease was discovered to be a glycosphingolipidosis. Enzymes of lysosomal metabolism of glycosphingolipids were purified, characterized, and used in one of the first demonstrations of the feasibility of enzyme replacement therapy in a lysosomal storage disorder (Fabry’s disease). Extracellular sialidases were studied to evaluate the hypothesis that they might be involved in the regulation of membrane growth factor receptors. The enzyme for hematoside synthesis was purified and characterized. PMID:20948176

Promising New Directions in Biochemistry

ERIC Educational Resources Information Center

Olivera, Baldomero M.

2003-01-01

"Biochemistry," by Lubert Stryer, has become one of the standard textbooks for the field. The Fifth Edition has two new authors: Jeremy Berg, Professor and Director of Biophysics and Biophysical Chemistry at Johns Hopkins University School of Medicine; and John Tymoczko, the Towsley Professor of Biology at Carleton College. The new edition does,…

The Human Domain and the Future of Army Warfare: Present as Prelude to 2050

DTIC Science & Technology

2017-07-01

ERDC/CERL MP-17-2 ii Abstract Studies on the future of warfare tend to focus on technology and place but largely overlook the actors. Warfare in 2050...will be predominantly urban, utilizing robotics and other advanced technologies , but at the core will re- main an inherently human and political...collaboration for success. Despite the ap- peal of advanced technology , the U.S. Army could greatly benefit by looking beyond strictly technological

Nanoplatforms for Detection, Remediation and Protection Against Chem-Bio Warfare

NASA Astrophysics Data System (ADS)

Denkbaş, E. B.; Bayram, C.; Kavaz, D.; Çirak, T.; Demirbilek, M.

Chemical and biological substances have been used as warfare agents by terrorists by varying degree of sophistication. It is critical that these agents be detected in real-time with high level of sensitively, specificity, and accuracy. Many different types of techniques and systems have been developed to detect these agents. But there are some limitations in these conventional techniques and systems. Limitations include the collection, handling and sampling procedures, detection limits, sample transfer, expensive equipment, personnel training, and detection materials. Due to the unique properties such as quantum effect, very high surface/volume ratio, enhanced surface reactivity, conductivity, electrical and magnetic properties of the nanomaterials offer great opportunity to develop very fast, sensitive, accurate and cost effective detection techniques and systems to detect chemical and biological (chem.-bio) warfare agents. Furthermore, surface modification of the materials is very easy and effective way to get functional or smart surfaces to be used as nano-biosensor platform. In that respect many different types of nanomaterials have been developed and used for the detection, remediation and protection, such as gold and silver nanoparticles, quantum dots, Nano chips and arrays, fluorescent polymeric and magnetic nanoparticles, fiber optic and cantilever based nanobiosensors, nanofibrillar nanostructures etc. This study summarizes preparation and characterization of nanotechnology based approaches for the detection of and remediation and protection against chem.-bio warfare agents.

Case Study of How Turkish University Students Improve Their Biochemistry Achievement

ERIC Educational Resources Information Center

Sadi, Özlem

2013-01-01

Biochemistry courses have an important place as a common subject in faculties of medicine, food engineering, biology and chemistry. MSLQ, Metacognitive Awareness Inventory and Learning Approach Questionnaire were used. The study also involves repeated observations of the same instructor in a biochemistry class over eight weeks to describe…

A Biochemistry of Human Disease Course for Undergraduate and Graduate Students.

ERIC Educational Resources Information Center

Glew, Robert H.; VanderJagt, David L.

2001-01-01

Describes the experiences of a medical school faculty who have been offering for more than 10 years a two-course series in the biochemistry of human disease to undergraduate students majoring in biochemistry, biology, or chemistry. Recommends the teaching of specialized, advanced courses to undergraduate, pre-professional students. (DDR)

The Cyber Warfare Professional: Realizations for Developing the Next Generation

DTIC Science & Technology

2011-01-01

consequences for the others. However, just as airpower soon emerged as a revolution in military affairs during the early twentieth century, so may cyber warfare become the next revolution for the new millennium.

Use of mushroom tyrosinase to introduce michaelis-menten enzyme kinetics to biochemistry students.

PubMed

Flurkey, William H; Inlow, Jennifer K

2017-05-01

An inexpensive enzyme kinetics laboratory exercise for undergraduate biochemistry students is described utilizing tyrosinase from white button mushrooms. The exercise can be completed in one or two three-hour lab sessions. The optimal amounts of enzyme, substrate (catechol), and inhibitor (kojic acid) are first determined, and then kinetic data is collected in the absence and presence of the inhibitor. A Microsoft Excel template is used to plot the data and to fit the Michaelis-Menten equation to the data to determine the kinetic parameters V max and K m . The exercise is designed to clarify and reinforce concepts covered in an accompanying biochemistry lecture course. It has been used with positive results in an upper-level biochemistry laboratory course for junior/senior students majoring in chemistry or biology. © 2016 by The International Union of Biochemistry and Molecular Biology, 45(3):270-276, 2017. © 2016 The International Union of Biochemistry and Molecular Biology.

History of chemical and biological warfare agents.

PubMed

Szinicz, L

2005-10-30

Chemical and biological warfare agents constitute a low-probability, but high-impact risk both to the military and to the civilian population. The use of hazardous materials of chemical or biological origin as weapons and for homicide has been documented since ancient times. The first use of chemicals in terms of weapons of mass destruction goes back to World War I, when on April 22, 1915 large amounts of chlorine were released by German military forces at Ypres, Belgium. Until around the 1970s of the 20th century, the awareness of the threat by chemical and biological agents had been mainly confined to the military sector. In the following time, the development of increasing range delivery systems by chemical and biological agents possessors sensitised public attention to the threat emanating from these agents. Their proliferation to the terrorists field during the 1990s with the expanding scale and globalisation of terrorist attacks suggested that these agents are becoming an increasing threat to the whole world community. The following article gives a condensed overview on the history of use and development of the more prominent chemical and biological warfare agents.

Management of chemical warfare injuries (on CD-ROM). Data file

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-08-01

The threat of use of chemical warfare agents (agents of `mass destruction`) is no longer confined to the battlefield. Agent releases by terrorists in Japan in 1995 served to awaken the world to the dangers faced by civilian communities far removed from centers of armed conflict. The ability to save lives in the event of a chemical agent release turns on provision of immediate and correct medical care in the field and hospital. Being able to ensure availability of life-saving care depends on reaching both military and civilian medical personnel with information on chemical warfare agents and on keeping theirmore » skills and knowledge current. While this is of critical importance both to the Department of Defense and to civilian agencies charged with protecting the public, it also is a daunting and potentially expensive task in view of the numbers and geographic dispersion of persons to be trained. The Department of Defense has addressed and overcome these challenges, to the benefit of the military and civilians, by using computer technology as the vehicle by which cost-effective chemical warfare agent training may be conveniently delivered to all who require it. The multi-media instructional program, Management of Chemical Warfare Injuries, was developed for military use by the Naval Health Sciences Education and Training Command, with the technical assistance of the U.S. Army Medical Command. It was originally designed for delivery via video disc, a format used extensively within the Navy. However, in response to a request from the Federal Emergency Management Agency, the Office of the Secretary of Defense agreed to repackage the materials for delivery on CD-ROM in order to make them accessible to a larger audience. In addition, the Navy agreed to include on the two CD-ROMs which contain the program a ready reference not found on the video disc: the Army`s `Medical Management of Chemical Casualties` handbooks for field and medical personnel.« less

Air Power and Warfare: A Supplement

DTIC Science & Technology

2002-02-01

The Aeronautical History Collection of Colonel Richard Gimbel. , This bibliography, Number 99 in the Library’s Special Bibliography Series, was...H848 1992) Kohn, Richard H., and Joseph P. Harahan. Air Superiority in World War II and Korea: An Interview with Gen. James Fereuson, Gen. Robert M...Mark A. "Airpower as a Second Front." Airpowcr Journal 9 (Fall 1995): 63-73 Hallion, Richard P. "Airpower and the Changing Nature of Warfare." Joint

The Use of Contextual Learning to Teach Biochemistry to Dietetic Students

ERIC Educational Resources Information Center

Macaulay, J. O.; Van Damme, M. -P.; Walker, K. Z.

2009-01-01

This article describes the use of contextualized and "blended" learning to teach biochemistry to dietetic students during the second year of their professional training in a 4-year undergraduate degree (Bachelor of Nutrition and Dietetics). Contextualized content was used to engage students and motivate them to learn biochemistry, which many…

Oxygen-Free Biochemistry: The Putative CHN Foundation for Exotic Life in a Hydrocarbon World?

NASA Astrophysics Data System (ADS)

Lv, Kong-Peng; Norman, Lucy; Li, Yi-Liang

2017-11-01

Since Earth's biochemistry is carbon-based and water-borne, the main strategies for searching for life elsewhere are "follow the carbon" and "follow the water." Recently, however, there is a growing focus on the prospect that putative exotic life on other planets could rely on unearthly biochemistries. Here, we hypothesize a novel oxygen-free organic chemistry for supporting potential exotic biosystems, which is named CHN biochemistry. This oxygen-free CHN biochemistry starts from simple oxygen-free species (including hydrocarbons, hydrogen cyanide, and nitriles) and produces a range of functional macromolecules that may function in similar ways to terran macromolecules, such as sugars (cyanosugars), acids (cyanoacids), amino acids (amino cyanoacids), and nucleobases (cyanonucleobases). These CHN macromolecules could further interact with each other to generate higher "cyanoester" and "cyanoprotein" systems. In addition, theoretical calculations indicate that the energy changes of some reactions are consistent with their counterparts in Earth's biochemistry. The CHN biochemistry-based life would be applicable in habitats with a low bioavailability of oxygen, such as the alkane lakes of Titan and non-aquatic liquids on extrasolar bodies.

Unconventional Warfare in the American Civil War

DTIC Science & Technology

2004-06-18

Miller Thesis Title: Unconventional Warfare in the American Civil War Approved by: , Thesis Committee Chair LTC ( R ) Gregory T. Beck...M.A. , Member LTC ( R ) Richard Barbuto, Ph.D. , Consulting Faculty LTC ( R ) James B. Martin, Ph.D. Accepted this 18th day of...troops and supplies to forward areas. In official correspondence dated 26 May 1864 from Captain A. V. Barringer , Chief Quartermaster, Department of West

Electronic warfare antenna systems - Past and present

NASA Astrophysics Data System (ADS)

Yaw, D.

1981-09-01

In discussing fixed beam arrays, it is noted that an array may be used to create simultaneous fixed beams or to form asymmetric beams of a desired shape. Attention is also given to arrays and beam control, noting that for some electronic warfare applications combinations of broad and narrow beam antenna response are needed. Other topics include ECM jamming antenna techniques and advanced array systems.

Predictors of performance of students in biochemistry in a doctor of chiropractic curriculum.

PubMed

Shaw, Kathy; Rabatsky, Ali; Dishman, Veronica; Meseke, Christopher

2014-01-01

Objective : This study investigated the effect of completion of course prerequisites, undergraduate grade point average (GPA), undergraduate degree, and study habits on the performance of students in the biochemistry course at Palmer College of Chiropractic Florida. Methods : Students self-reported information regarding academic preparation at the beginning of the semester using a questionnaire. Final exam grade and final course grade were noted and used as measures of performance. Multivariate analysis of variance was used to determine if number of prerequisites completed, undergraduate GPA, undergraduate degree, hours spent studying in undergraduate study, and hours spent studying in the first quarter of the chiropractic program were associated significantly with the biochemistry final exam grade or the final grade for the biochemistry course. Results : The number of prerequisites completed, undergraduate degree, hours spent studying in undergraduate study, and hours spent studying in the first quarter of the chiropractic program did not significantly affect the biochemistry final exam grade or the final grade for the biochemistry course, but undergraduate GPA did. Subsequent univariate analysis and Tukey's post hoc comparisons revealed that students with an undergraduate GPA in the 3.5 to 3.99 range earned significantly higher final course grades than students with an undergraduate GPA in the 2.5 to 2.99 range. Conclusion : No single variable was determined to be a factor that determines student success in biochemistry. The interrelationship between the factors examined warrants further investigation to understand fully how to predict the success of a student in the biochemistry course.

Lignin biochemistry and soil N determine crop residue decomposition and soil priming

USDA-ARS?s Scientific Manuscript database

Cropping history can affect soil properties, including available N, but little is known about the interactive effects of residue biochemistry, temperature and cropping history on residue decomposition. A laboratory incubation examined the role of residue biochemistry and temperature on the decomposi...

Pirates of the Nuclear Age: The Role of U.S. Submarines in Modern Trade Warfare

DTIC Science & Technology

2016-07-14

have sought to influence the outcome of the conflict by targeting enemy commerce . This influence historically called for the use of privateers...submarines took the position of privateers as the ideal force for conducting commerce warfare. Throughout World War Two (WWII) commerce warfare using... commerce ) remains. From the time of Greek city-states, to the privateers of the age of sail, to the submarines of WWI and WWII, targeting the

Biochemistry students' ideas about how an enzyme interacts with a substrate.

PubMed

Linenberger, Kimberly J; Bretz, Stacey Lowery

2015-01-01

Enzyme-substrate interactions are a fundamental concept of biochemistry that is built upon throughout multiple biochemistry courses. Central to understanding enzyme-substrate interactions is specific knowledge of exactly how an enzyme and substrate interact. Within this narrower topic, students must understand the various binding sites on an enzyme and be able to reason from simplistic lock and key or induced fit models to the more complex energetics model of transition state theory. Learning to understand these many facets of enzyme-substrate interactions and reasoning from multiple models present challenges where students incorrectly make connections between concepts or make no connection at all. This study investigated biochemistry students' understanding of enzyme-substrate interactions through the use of clinical interviews and a national administration (N = 707) of the Enzyme-Substrate Interactions Concept Inventory. Findings include misconceptions regarding the nature of enzyme-substrate interactions, naïve ideas about the active site, a lack of energetically driven interactions, and an incomplete understanding of the specificity pocket. © 2015 by the International Union of Biochemistry and Molecular Biology.

Gender Performance Differences in Biochemistry

ERIC Educational Resources Information Center

Rauschenberger, Matthew M.; Sweeder, Ryan D.

2010-01-01

This study examined the historical performance of students at Michigan State University in a two-part biochemistry series Biochem I (n = 5,900) and Biochem II (n = 5,214) for students enrolled from 1997 to 2009. Multiple linear regressions predicted 54.9-87.5% of the variance in student from Biochem I grade and 53.8-76.1% of the variance in…

Useful Demonstrations for a Medial Biochemistry Course.

ERIC Educational Resources Information Center

Ragatz, Barth H.; Modrak, Gina

1986-01-01

Describes six demonstrations used in a medical biochemistry course. These demonstrations focus on: (1) platelet aggregometry; (2) ion-transporting antibiotics; (3) glycosylated hemoglobin; (4) molecular models; (5) serum preparation; and (6) bioluminescence. (JN)

Countering Gray-Zone Hybrid Threats: An Analysis of Russias New Generation Warfare and Implications for the US Army

DTIC Science & Technology

2016-10-18

education ...Publication (JP) 1, Doctrine for the Armed Forces of the United States, there are two forms of warfare, traditional and irregular, and...combat mission in 2010. Looking at OIF, the US Army participated in both traditional and irregular warfare and the characterization of

Suitable Class Experiments in Biochemistry for High-school Chemistry and Biology Courses.

ERIC Educational Resources Information Center

Myers, A.

1987-01-01

Illustrates the scope of experimental investigations for biochemistry education in high school biology and chemistry courses. Gives a brief overview of biochemistry experiments with proteins, enzymes, carbohydrates, lipids, nucleic acids, vitamins, metabolism, electron transport, and photosynthesis including materials, procedures, and outcomes.…

Biochemistry of epidermal stem cells.

PubMed

Eckert, Richard L; Adhikary, Gautam; Balasubramanian, Sivaprakasam; Rorke, Ellen A; Vemuri, Mohan C; Boucher, Shayne E; Bickenbach, Jackie R; Kerr, Candace

2013-02-01

The epidermis is an important protective barrier that is essential for maintenance of life. Maintaining this barrier requires continuous cell proliferation and differentiation. Moreover, these processes must be balanced to produce a normal epidermis. The stem cells of the epidermis reside in specific locations in the basal epidermis, hair follicle and sebaceous glands and these cells are responsible for replenishment of this tissue. A great deal of effort has gone into identifying protein epitopes that mark stem cells, in identifying stem cell niche locations, and in understanding how stem cell populations are related. We discuss these studies as they apply to understanding normal epidermal homeostasis and skin cancer. An assortment of stem cell markers have been identified that permit assignment of stem cells to specific regions of the epidermis, and progress has been made in understanding the role of these cells in normal epidermal homeostasis and in conditions of tissue stress. A key finding is the multiple stem cell populations exist in epidermis that give rise to different structures, and that multiple stem cell types may contribute to repair in damaged epidermis. Understanding epidermal stem cell biology is likely to lead to important therapies for treating skin diseases and cancer, and will also contribute to our understanding of stem cells in other systems. This article is part of a Special Issue entitled Biochemistry of Stem Cells. Copyright © 2012 Elsevier B.V. All rights reserved.

Biochemistry of epidermal stem cells☆

PubMed Central

Eckert, Richard L.; Adhikary, Gautam; Balasubramanian, Sivaprakasam; Rorke, Ellen A.; Vemuri, Mohan C.; Boucher, Shayne E.; Bickenbach, Jackie R.; Kerr, Candace

2014-01-01

Background The epidermis is an important protective barrier that is essential for maintenance of life. Maintaining this barrier requires continuous cell proliferation and differentiation. Moreover, these processes must be balanced to produce a normal epidermis. The stem cells of the epidermis reside in specific locations in the basal epidermis, hair follicle and sebaceous glands and these cells are responsible for replenishment of this tissue. Scope of review A great deal of effort has gone into identifying protein epitopes that mark stem cells, in identifying stem cell niche locations, and in understanding how stem cell populations are related. We discuss these studies as they apply to understanding normal epidermal homeostasis and skin cancer. Major conclusions An assortment of stem cell markers have been identified that permit assignment of stem cells to specific regions of the epidermis, and progress has been made in understanding the role of these cells in normal epidermal homeostasis and in conditions of tissue stress. A key finding is the multiple stem cell populations exist in epidermis that give rise to different structures, and that multiple stem cell types may contribute to repair in damaged epidermis. General significance Understanding epidermal stem cell biology is likely to lead to important therapies for treating skin diseases and cancer, and will also contribute to our understanding of stem cells in other systems. This article is part of a Special Issue entitled Biochemistry of Stem Cells. PMID:22820019

The Physiology and Biochemistry of Receptors.

ERIC Educational Resources Information Center

Spitzer, Judy A., Ed.

1983-01-01

The syllabus for a refresher course on the physiology and biochemistry of receptors (presented at the 1983 American Physiological Society meeting) is provided. Topics considered include receptor regulation, structural/functional aspects of receptors for insulin and insulin-like growth factors, calcium channel inhibitors, and role of lipoprotein…

Comparative biochemistry and physiology in Brazil: a critical appraisal.

PubMed

Navas, Carlos Arturo; Chaui-Berlinck, José Guilherme; Bicudo, José Eduardo P W; Pivello, Vânia R; Martins, Marcio

2007-07-01

Brazil stood out as the country with the highest number of submissions to the editorial project dedicated to Latin America by the journal Comparative Biochemistry and Physiology. Therefore, we felt that it was important to critically discuss the state of comparative biochemistry and physiology in this country. Our study is based on data collected from the ISI Web-of-Science. We analyzed publication trends through time, availability of novel approaches and techniques, patterns of collaboration among different geographical regions, patterns of collaboration with researchers abroad, and relative efforts dedicated to the study of biochemical and physiological adaptation of native fauna representing different terrestrial Brazilian biomes. Overall, our data shows that comparative biochemistry and physiology is a lively and productive discipline, but that some biases limit the scope of the field in Brazil. Some important limitations are the very heterogeneous distribution of research nuclei throughout the country and the absence of some important approaches, such as remote sensing and the use of molecular biology techniques in a comparative or evolutionary context. We also noticed that international collaboration far surpasses interregional collaboration, and discuss the possible causes and consequences of this situation. Finally, we found that Brazilian comparative biochemistry and physiology is biome-biased, as the Amazonian fauna has received far more attention than the whole pool of fauna representing other terrestrial biomes. We discuss the possible causes of these biases, and propose some directions that may contribute to invigorate the field in the country.

Plasma biochemistry RIs and age effect in European Strigiformes.

PubMed

Agusti Montolio, Susana; Cuenca Valera, Rafaela; Lavín González, Santiago; Cray, Carolyn; Molina López, Rafael; Ferron, Emmanuel Serrano; Francisco, Olga Nicolás; Marco Sánchez, Ignasi; Casas-Díaz, Encarna

2018-03-01

Blood biochemistry and hematology are essential in the laboratory diagnosis of disease. In Strigiformes, little information regarding reference values and influence of different preanalytic factors is available, while age is known to have an effect on some biochemistry analytes, especially in early life characterized by a rapid growth rate and increase in body mass. The objective of this study was to determine baseline data for 29 blood biochemistry variables in 5 species of Iberian Strigiformes assigned to different age classes. Healthy nocturnal birds living in wildlife health centers of Catalonia, Northeastern Spain were assigned to different age classes (chicks, juveniles, adults where possible and available) and their blood was collected and analyzed for different standard biochemistry variables. Species included Tawny owls, Little owls, Long-eared owls, Scop owls, and Barn owls. A total of 276 clinically healthy animals were sampled, including between 179 chicks, 52 juveniles, and 45 adults. The RIs of cholesterol, albumin, and osmolality were the only variables that did not show interspecific variability. Common trends between age class groups were observed in 4 species. Phosphorus and calcium concentrations and ALP activities decreased with increasing age, while concentrations of sodium and γ-globulins tended to increase in the Strigidae family. Differences were concentrated in chicks and no differences were observed between juveniles and adults in any variable. Our results demonstrate the importance of defining biochemical RIs specific for certain age classes. © 2018 American Society for Veterinary Clinical Pathology.

Glycobiology, how to sugar-coat an undergraduate advanced biochemistry laboratory.

PubMed

McReynolds, Katherine D

2006-09-01

A second semester biochemistry laboratory has been implemented as an independent projects course at California State University, Sacramento since 1999. To incorporate aspects of carbohydrate biochemistry, or glycobiology, into our curriculum, projects in lectin isolation and purification were undertaken over the course of two semesters. Through this modification in course content, this class now offers a diverse, hands-on treatment of not only standard protein purification techniques but also carbohydrate techniques, specifically the study of carbohydrate-protein interactions through hemagglutination assays, a novel commercial assay known as the Instant™Chek assay, and the generation and use of appropriate affinity chromatography matrices. Throughout the semester, the students are in charge of all aspects of their projects, from planning to execution and completion. Specific examples of student projects are highlighted such that the breadth of protein-carbohydrate chemistry pursued in a 15-week semester can be appreciated. The feedback of the course was very favorable, indicating that the students came away with skills necessary for them to be successful in their future careers. Most importantly, however, aspects of glycobiology have now been incorporated effectively into a mainstream undergraduate biochemistry laboratory class. Copyright © 2006 International Union of Biochemistry and Molecular Biology, Inc.

Biodiversity conservation and armed conflict: a warfare ecology perspective.

PubMed

Hanson, Thor

2018-04-23

The activities involved in preparing for, executing, and recovering from armed conflict are globally pervasive and consequential, with significant impacts on natural systems. Effects on biodiversity are predominantly negative, produced by direct and indirect battlefield impacts, as well as the general breakdown of social, economic, and governance systems during wartime. Certain conservation opportunities do occur, however, particularly on lands set aside for training exercises, buffer zones, and peace parks. Here, the relationship between armed conflict and biodiversity is reviewed using the temporal framework of warfare ecology, which defines warfare as an ongoing process of three overlapping stages: preparations, war (armed conflict), and postwar activities. Several themes emerge from recent studies, including a heightened awareness of biodiversity conservation on military lands, the potential for scientific and conservation engagement to mitigate negative biodiversity impacts in war zones, and the importance of the postwar period for incorporating biodiversity priorities into reconstruction and recovery efforts. Research limitations and knowledge gaps are also discussed. © 2018 New York Academy of Sciences.

The United States and biological warfare: secrets from the early cold war and Korea.

PubMed

Bruwer, A

2001-01-01

The United States and Biological Warfare is about accusations that the United States resorted to bacteriological warfare at a time of great military stress during the Korean War. In December 1951, the then US Secretary of Defense ordered early readiness for offensive use of biological weapons. Soon afterwards, the North Korean and Chinese armies accused the United States of starting a large-scale biological warfare experiment in Korea. The US State Department denied the accusation. Both parties to the dispute maintain their positions today. The authors spent 20 years researching the accusations in North America, Europe and Japan. They were the first foreigners to be given access to Chinese classified documents. The reader is also introduced to the concept of 'plausible denial', an official US policy which allowed responsible governmental representatives to deny knowledge of certain events. The authors hope that their work will contribute to the understanding of a time when modern war expanded into a new type of violence.

Impact of e-resources on learning in biochemistry: first-year medical students' perceptions.

PubMed

Varghese, Joe; Faith, Minnie; Jacob, Molly

2012-05-16

E-learning resources (e-resources) have been widely used to facilitate self-directed learning among medical students. The Department of Biochemistry at Christian Medical College (CMC), Vellore, India, has made available e-resources to first-year medical students to supplement conventional lecture-based teaching in the subject. This study was designed to assess students' perceptions of the impact of these e-resources on various aspects of their learning in biochemistry. Sixty first-year medical students were the subjects of this study. At the end of the one-year course in biochemistry, the students were administered a questionnaire that asked them to assess the impact of the e-resources on various aspects of their learning in biochemistry. Ninety-eight percent of students had used the e-resources provided to varying extents. Most of them found the e-resources provided useful and of a high quality. The majority of them used these resources to prepare for periodic formative and final summative assessments in the course. The use of these resources increased steadily as the academic year progressed. Students said that the extent to which they understood the subject (83%) and their ability to answer questions in assessments (86%) had improved as a result of using these resources. They also said that they found biochemistry interesting (73%) and felt motivated to study the subject (59%). We found that first-year medical students extensively used the e-resources in biochemistry that were provided. They perceived that these resources had made a positive impact on various aspects of their learning in biochemistry. We conclude that e-resources are a useful supplement to conventional lecture-based teaching in the medical curriculum.

Why people believe they were exposed to biological or chemical warfare: a survey of Gulf War veterans.

PubMed

Brewer, Noel T; Lillie, Sarah E; Hallman, William K

2006-04-01

The study sought to understand better how people come to believe they have been exposed to biological and chemical warfare. We conducted telephone interviews with 1,009 American veterans (65% response rate) deployed and not deployed to the Gulf War, a conflict during which there were credible threats that such warfare could be used. Only 6% of non-Gulf War veterans reported exposure to biological or chemical warfare, but most of Gulf War veterans reported exposure (64%). The majority of these were unsure whether the exposure was chemical or biological in nature. The most commonly reported exposure indicators were receiving an alert from the military and having physical symptoms. Veterans who were certain of the type of exposure (biological or chemical) were more likely to recall having been told by the military and to recall physical symptoms. Future communications with soldiers and the general public about biological and chemical warfare may need to emphasize the uncertain nature of such risk information. Evaluations of exposure diagnostic technologies should take into account the problem of people initially believing, but not later discounting, false positive results.

Playing with a double-edged sword: Analogies in biochemistry

NASA Astrophysics Data System (ADS)

Orgill, Marykay

Analogy pervades our everyday reasoning. No situation we encounter is exactly like a situation we have encountered previously, and our ability to learn and survive in the world is based on our ability to find similarities between past and present situations and use the knowledge we have gained from past situations to manage current situations. Analogies can be powerful teaching tools because they can make new material intelligible to students by comparing it to material that is already familiar. It is clear, though, that not all analogies are good and that not all good analogies are useful to all students. In this study, I have used textbook analysis, classroom observations, student interviews and instructor interviews to determine the role that analogies play in biochemistry learning. Analogies are an important teaching technique in biochemistry classes, being used more often in both biochemistry classes and textbooks than they are in high school chemistry classes and textbooks. Most biochemistry students like, pay particular attention to, and remember the analogies their instructors provide; and they use these analogies to understand, visualize, and recall information from class. Even though students like and use analogies, they do not understand what analogies are or the mechanism by which they improve learning. For the students, analogies are simply any teaching technique that eases understanding, visualization, or recall. Instructors, on the other hand, have a good understanding of what analogies are and of how they should be presented in class; but they do not use analogies as effectively as they should. They do not plan, explain or identify the limitations of the analogies they use in class. However, regardless of how effectively instructors present analogies in class, this study indicates that, in general, analogies are useful in promoting understanding, visualization, recall, and motivation in biochemistry students at all levels. They would be even more

Teaching Receptor Theory to Biochemistry Undergraduates

ERIC Educational Resources Information Center

Benore-Parsons, Marilee; Sufka, Kenneth J.

2003-01-01

Receptor:ligand interactions account for numerous reactions critical to biochemistry and molecular biology. While students are typically exposed to some examples, such as hemoglobin binding of oxygen and signal transduction pathways, the topic could easily be expanded. Theory and kinetic analysis, types of receptors, and the experimental assay…

Rhetorical Structure of Biochemistry Research Articles

ERIC Educational Resources Information Center

Kanoksilapatham, Budsaba

2005-01-01

This paper reports on the results of a move analysis [Swales, J. (1990). "Genre analysis." Cambridge: Cambridge University Press] of 60 biochemistry research articles. First, a corpus was systematically compiled to ensure that it represents core journals in the focused discipline. Then, coding reliability analysis was conducted to…

Al Qaeda and Fourth Generation Warfare as its Strategy

DTIC Science & Technology

2008-01-01

and materia ~ as well as money, from one point ofthe non- linear battlefield to another, thereby giving more flexibility to obtain the right materials...translated by Griffith, Samuel B., On Guerilla Warfare, (1937),21-22. 14 Bodansky, Yossef, Bin Laden The Man Who Declared War on America (Rocklin: Prima

Tagging and purifying proteins to teach molecular biology and advanced biochemistry.

PubMed

Roecklein-Canfield, Jennifer A; Lopilato, Jane

2004-11-01

Two distinct courses, "Molecular Biology" taught by the Biology Department and "Advanced Biochemistry" taught by the Chemistry Department, complement each other and, when taught in a coordinated and integrated way, can enhance student learning and understanding of complex material. "Molecular Biology" is a comprehensive lecture-based course with a 3-h laboratory once a week, while "Advanced Biochemistry" is a completely laboratory-based course with lecture fully integrated around independent student projects. Both courses emphasize and utilize cutting-edge technology. Teaching across departmental boundaries allows students access to faculty expertise and techniques rarely used at the undergraduate level, namely the tagging of proteins and their use in protein purification. Copyright © 2004 International Union of Biochemistry and Molecular Biology, Inc.

Evolutionary biochemistry: revealing the historical and physical causes of protein properties

PubMed Central

Harms, Michael J.; Thornton, Joseph W.

2014-01-01

The repertoire of proteins and nucleic acids in the living world is determined by evolution; their properties are determined by the laws of physics and chemistry. Explanations of these two kinds of causality — the purviews of evolutionary biology and biochemistry, respectively — are typically pursued in isolation, but many fundamental questions fall squarely at the interface of fields. Here we articulate the paradigm of evolutionary biochemistry, which aims to dissect the physical mechanisms and evolutionary processes by which biological molecules diversified and to reveal how their physical architecture facilitates and constrains their evolution. We show how an integration of evolution with biochemistry moves us towards a more complete understanding of why biological molecules have the properties that they do. PMID:23864121

Teaching arrangements of carbohydrate metabolism in biochemistry curriculum in Peking University Health Science Center.

PubMed

Chen, Hao; Ni, Ju-Hua

2013-01-01

Biochemistry occupies a unique place in the medical school curricula, but the teaching of biochemistry presents certain challenges. One of these challenges is facilitating students' interest in and mastery of metabolism. The many pathways and modes of regulation can be overwhelming for students to learn and difficult for professors to teach in an engaging manner. The first chapter of the metabolism section in current Chinese biochemistry textbooks covers carbohydrate metabolism. Medical students usually complain about the difficulty of this subject. Here we discuss how to facilitate learning by rearranging the subjects in this introductory chapter of biochemical metabolism and to lay a solid foundation for future study. The strategy involves reorganizing the order in which subjects are taught from simple to complex and from short to long metabolic pathways. Most students taking the curriculum consider that the strategy engages their learning interests in biochemistry and enhances their learning outcomes. Copyright © 2013 International Union of Biochemistry and Molecular Biology, Inc.

Identification of Threshold Concepts for Biochemistry

ERIC Educational Resources Information Center

Loertscher, Jennifer; Green, David; Lewis, Jennifer E.; Lin, Sara; Minderhout, Vicky

2014-01-01

Threshold concepts (TCs) are concepts that, when mastered, represent a transformed understanding of a discipline without which the learner cannot progress. We have undertaken a process involving more than 75 faculty members and 50 undergraduate students to identify a working list of TCs for biochemistry. The process of identifying TCs for…

Combining Content and Elements of Communication into an Upper-Level Biochemistry Course

ERIC Educational Resources Information Center

Whittington, Carli P.; Pellock, Samuel J.; Cunningham, Rebecca L.; Cox, James R.

2014-01-01

This report describes how a science communication module was incorporated into an advanced biochemistry course. Elements of communication were taught synergistically with biochemistry content in this course in an effort to expose students to a variety of effective oral communication strategies. Students were trained to use these established…

Blended learning in biochemistry education: analysis of medical students' perceptions.

PubMed

de Fátima Wardenski, Rosilaine; de Espíndola, Marina Bazzo; Struchiner, Miriam; Giannella, Taís Rabetti

2012-07-01

The objective of this study was to analyze first-year UFRJ medical students' perceptions about the implementation of a blended learning (BL) experience in their Biochemistry I course. During the first semester of 2009, three Biochemistry professors used the Constructore course management system to develop virtual learning environments (VLEs) for complementing course Modules I, II, and IV, using different resources and activities. Forty-nine students (46%) took part in the study. Results show that, in general, students gave positive evaluations to their experiences with BL, indicating that the VLEs have not only motivated but also facilitated learning. Most of the students reported that access to resources in the three modules provided a more in-depth approach to Biochemistry education and greater study autonomy. Students suggested that the VLEs could be better used for promoting greater communication among participants. Copyright © 2012 Wiley Periodicals, Inc.

Naval Surface Warfare Center Carderock Division, Technical Digest

DTIC Science & Technology

2001-12-01

Survivability Systems: An Overview Fred J. Fisch 139 Modeling and Simulation of Weapons Effects on Ships Robert R. Wunderlick 143 Intelligent Networks ...communications capability of forces afloat to support emerging network -centric warfare doc- trines. Stealth, for our next generation of warships...fully-inte- grated, fully- networked electronic countermeasures system, developed in parallel and in close coordination with sister systems. An

A course director's perspectives on problem-based learning curricula in biochemistry.

PubMed

Smith, Harold C

2002-12-01

Knowledge of the applications of biochemistry, molecular biology, and genetics in the practice of medicine has been and continues to be a vital part of medical students' and continuing education. The technical background and the rapid expansion of information and new applications have made it an arduous task to learn and teach this material within the already crowded medical school curriculum. Problem-based learning (PBL) formats are rapidly being adopted at all levels of education as not only a major paradigm shift in education but also a solution for the instruction of biochemistry in medical school. Designing an effective biochemistry curriculum with PBL-based or lecture-based formats requires an appreciation for their strengths and weakness. The author's experiences in the Double Helix Curriculum at the University of Rochester School of Medicine and Dentistry (which employs PBL cases and complementing lectures) has shown that students are excited about learning in the PBL environment and explore in depth ways of integrating biochemistry, cell biology, genetics, and molecular biology into the practice of medicine. At the same time, complementary lectures greatly enhance uniformity in the quality and, importantly, the accuracy of the students' learning.

Impact of e-resources on learning in biochemistry: first-year medical students’ perceptions

PubMed Central

2012-01-01

Background E-learning resources (e-resources) have been widely used to facilitate self-directed learning among medical students. The Department of Biochemistry at Christian Medical College (CMC), Vellore, India, has made available e-resources to first-year medical students to supplement conventional lecture-based teaching in the subject. This study was designed to assess students’ perceptions of the impact of these e-resources on various aspects of their learning in biochemistry. Methods Sixty first-year medical students were the subjects of this study. At the end of the one-year course in biochemistry, the students were administered a questionnaire that asked them to assess the impact of the e-resources on various aspects of their learning in biochemistry. Results Ninety-eight percent of students had used the e-resources provided to varying extents. Most of them found the e-resources provided useful and of a high quality. The majority of them used these resources to prepare for periodic formative and final summative assessments in the course. The use of these resources increased steadily as the academic year progressed. Students said that the extent to which they understood the subject (83%) and their ability to answer questions in assessments (86%) had improved as a result of using these resources. They also said that they found biochemistry interesting (73%) and felt motivated to study the subject (59%). Conclusions We found that first-year medical students extensively used the e-resources in biochemistry that were provided. They perceived that these resources had made a positive impact on various aspects of their learning in biochemistry. We conclude that e-resources are a useful supplement to conventional lecture-based teaching in the medical curriculum. PMID:22510159

Enhanced podcasts for teaching biochemistry to veterinary students.

PubMed

Gough, Kevin C

2011-01-01

The teaching of biochemistry within medical disciplines presents certain challenges; firstly to relay a large body of complex facts and abstract concepts, and secondly to motivate students that this relatively difficult topic is worth their time to study. Here, nutrient biochemistry was taught within a multidisciplinary module as part of an undergraduate veterinary curriculum. The teaching approach was initially focussed on a mixture of didactic lectures and student-centred activities such as directed group/self learning. In subsequent years the core didactic lectures were replaced with enhanced podcasts covering the same material, along with the introduction of student presentations delivered within groups with both peer and facilitator assessment. These changes were accompanied by an increase in the time dedicated to this topic to allow sufficient time for students to work through podcasts and prepare presentations. The combination of these changes resulted in significant improvements in student performance within an in-course biochemistry long essay. These changes in the teaching approach, and particularly the introduction of extensive podcasts, was well received by students who perceived the process of going through the podcasts as time consuming but allowing them flexibility in both the pace that they studied this topic as well as the location and times that they studied it. Copyright © 2011 Wiley Periodicals, Inc.

Teaching and learning of medical biochemistry according to clinical realities: A case study.

PubMed

Jabaut, Joshua M; Dudum, Ramzi; Margulies, Samantha L; Mehta, Akshita; Han, Zhiyong

2016-01-01

To foster medical students to become physicians who will be lifelong independent learners and critical thinkers with healthy skepticism and provide high-quality patient care guided by the best evidence, teaching of evidence-based medicine (EBM) has become an important component of medical education. Currently, the teaching and learning of biochemistry in medical schools incorporates its medical relevance and applications. However, to our knowledge there have been no reports on integrating EBM with teaching and learning medical biochemistry. Here, we present a case study to illustrate the significance of this approach. This case study was based on a biochemistry/nutrition question in a popular board review book about whether a homeless alcoholic man is at risk of developing a deficiency of vitamin E. The possible answers and explanation provided in the book raised a question about the correct answer, which provided us with an opportunity to adapt the philosophy and certain basic EBM principles to find evidence for the clinical applicability of a commonly taught biochemistry topic. The outcome of this case study not only taught us how to conduct an EBM exercise to answer a specific patient question, but also provided us with an opportunity for in-depth teaching and learning of the medical relevance of a specific biochemistry topic based on the best clinical evidence obtained from a systematic research of medical literature. © 2015 The International Union of Biochemistry and Molecular Biology.

Particle Swarm Social Adaptive Model for Multi-Agent Based Insurgency Warfare Simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cui, Xiaohui; Potok, Thomas E

2009-12-01

To better understand insurgent activities and asymmetric warfare, a social adaptive model for modeling multiple insurgent groups attacking multiple military and civilian targets is proposed and investigated. This report presents a pilot study using the particle swarm modeling, a widely used non-linear optimal tool to model the emergence of insurgency campaign. The objective of this research is to apply the particle swarm metaphor as a model of insurgent social adaptation for the dynamically changing environment and to provide insight and understanding of insurgency warfare. Our results show that unified leadership, strategic planning, and effective communication between insurgent groups are notmore » the necessary requirements for insurgents to efficiently attain their objective.« less

Bridging the Gap in the Realm of Information Dominance: A Concept of Operations for the Naval Postgraduate School Center for Cyber Warfare

DTIC Science & Technology

2010-09-01

THE REALM OF INFORMATION DOMINANCE : A CONCEPT OF OPERATIONS FOR THE NAVAL POSTGRADUATE SCHOOL CENTER FOR CYBER WARFARE by Cynthia R. Duke...Bridging the Gap in the Realm of Information Dominance : A Concept of Operations for the Naval Postgraduate School Center for Cyber Warfare 6...of importance to the U.S. Military service and its allies. 15. NUMBER OF PAGES 102 14. SUBJECT TERMS Cyber Warfare, Information Dominance 16

New studies disputing allegations of bacteriological warfare during the Korean War.

PubMed

Rolicka, M

1995-03-01

In the television series Korea the Unknown War produced jointly by Thames Television (London) and WGBH (Boston) in 1990, General Matthew Ridgway, Commander in Chief of United Nations forces during the Korean War, called the accusations that the United States waged bacteriological warfare "black propaganda." The charges discredited the United States and, despite denials and many international discussions, have not been completely refuted until new. Following studies in archives previously not available for research and after uncovering new sources, many specific examples of black propaganda were discovered that contained false information and lies discrediting the United States. The mechanism of lies, which convinced the Korean population that bacteriological warfare was going on and that the only way not to become victims of the United States' inhuman cruelty was to fight, are shown in this paper.

Public Discussion of Nuclear Warfare: A Time for Hope.

ERIC Educational Resources Information Center

Cooper, Martha

Anti-nuclear discourse, which peaked in 1981-82, signaled an emergence of public discourse on the nuclear warfare issue. During the development of the original atomic bomb, public discussion of the issue was severely restricted, but immediately after the bombing of Hiroshima and Nagasaki, discourse on the subject increased. During the Cold War…

Punishment sustains large-scale cooperation in prestate warfare

PubMed Central

Mathew, Sarah; Boyd, Robert

2011-01-01

Understanding cooperation and punishment in small-scale societies is crucial for explaining the origins of human cooperation. We studied warfare among the Turkana, a politically uncentralized, egalitarian, nomadic pastoral society in East Africa. Based on a representative sample of 88 recent raids, we show that the Turkana sustain costly cooperation in combat at a remarkably large scale, at least in part, through punishment of free-riders. Raiding parties comprised several hundred warriors and participants are not kin or day-to-day interactants. Warriors incur substantial risk of death and produce collective benefits. Cowardice and desertions occur, and are punished by community-imposed sanctions, including collective corporal punishment and fines. Furthermore, Turkana norms governing warfare benefit the ethnolinguistic group, a population of a half-million people, at the expense of smaller social groupings. These results challenge current views that punishment is unimportant in small-scale societies and that human cooperation evolved in small groups of kin and familiar individuals. Instead, these results suggest that cooperation at the larger scale of ethnolinguistic units enforced by third-party sanctions could have a deep evolutionary history in the human species. PMID:21670285

Miniaturized low-cost ion mobility spectrometer for fast detection of chemical warfare agents.

PubMed

Zimmermann, Stefan; Barth, Sebastian; Baether, Wolfgang K M; Ringer, Joachim

2008-09-01

Ion mobility spectrometry (IMS) is a well-known method for detecting hazardous compounds in air. Typical applications are the detection of chemical warfare agents, highly toxic industrial compounds, explosives, and drugs of abuse. Detection limits in the low part per billion range, fast response times, and simple instrumentation make this technique more and more popular. In particular, there is an increasing demand for miniaturized low-cost IMS for hand-held devices and air monitoring of public areas by sensor networks. In this paper, we present a miniaturized aspiration condenser type ion mobility spectrometer for fast detection of chemical warfare agents. The device is easy to manufacture and allows single substance identification down to low part per billion-level concentrations within seconds. The improved separation power results from ion focusing by means of geometric constraints and fluid dynamics. A simple pattern recognition algorithm is used for the identification of trained substances in air. The device was tested at the German Armed Forces Scientific Institute for Protection Technologies-NBC-Protection. Different chemical warfare agents, such as sarin, tabun, soman, US-VX, sulfur mustard, nitrogen mustard, and lewisite were tested. The results are presented here.

An Undergraduate Biochemistry Laboratory Course with an Emphasis on a Research Experience

ERIC Educational Resources Information Center

Caspers, Mary Lou; Roberts-Kirchhoff, Elizabeth S.

2003-01-01

In their junior or senior year, biochemistry majors at the University of Detroit Mercy are required to take a two-credit biochemistry laboratory course. Five years ago, the format of this course was changed from structured experiments to a more project-based approach. Several structured experiments were included at the beginning of the course…

Need assessment of enhancing the weightage of applied biochemistry in the undergraduate curriculum at MGIMS, sevagram.

PubMed

Kumar, Satish; Jena, Lingaraja; Vagha, Jayant

2016-05-06

In order to review the need assessment of enhancing the weightage of Applied Biochemistry in the undergraduate curriculum at Mahatma Gandhi Institute of Medical Sciences (MGIMS), Sevagram, a validated questionnaire was sent to 453 participants which include 387 undergraduate students, 11 interns, 23 postgraduate students, and 32 faculty members. A web-based data collection and analysis tool was designed for online questionnaire distribution, data collection, and analysis. Response rate was 100%. Most of the respondents agreed that the subject Biochemistry has relevance in clinical practice (81.24%) and applied based learning of Biochemistry by medical undergraduates would help in overall improvement in the health standards/patients care (83.44%). According to 65.12% respondents, most of the medical undergraduates read Biochemistry just for examination purpose only. Nearly half of the respondents agreed that minute details of biochemical reactions were not much useful in clinical practice (53.86%) and the vast majority of diagrammatic cycles memorized by the medical undergraduates had no relevance in clinical practice (51.21%), the decreased interest in learning the Applied Biochemistry was due to more amount of clinically irrelevant information taught to medical undergraduates (73.51%), there was a need to rethink for removing the diagrammatic biochemical cycles from curriculum for medical undergraduates (48.12%), the less learning of Applied Biochemistry or competencies would affect the clinical skills and knowledge of medical undergraduates (70.42%). The result of this study suggests that there is need for restructuring the Biochemistry curriculum with more clinical relevance. © 2016 by The International Union of Biochemistry and Molecular Biology, 44:230-240, 2016. © 2016 The International Union of Biochemistry and Molecular Biology.

Learning effectiveness and satisfaction of international medical students: Introducing a Hybrid-PBL curriculum in biochemistry.

PubMed

Yan, Qiu; Ma, Li; Zhu, Lina; Zhang, Wenli

2017-07-08

A biochemistry course is a fundamental but important subject in medical education in China. In recent years, the number of international medical students has increased. Curriculum reform in biochemistry teaching is needed because of the knowledge limitations of students, a close linkage of biochemical content with clinics, the shortcomings of lecture-centered teaching, and the requirements for early clinical practice training and competence. In this study, we analyzed a novel curriculum reform, "Hybrid-PBL," which combined problem-based learning (PBL) with biochemistry lectures and was implemented for biochemical teaching at Dalian Medical University (DMU) in China. The change in curriculum affected 189 international medical students. This study selected two PBL cases concerning the basic biochemical issues of carbohydrate metabolism and liver biochemistry for the analysis, and ten examples of learning issues for each case were reported by the international students. A questionnaire was utilized to evaluate students' perceptions of the Hybrid-PBL, and examination scores were analyzed to assess the curriculum reform in biochemistry teaching. A statistical analysis revealed that the Hybrid-PBL curriculum was well accepted by the international students as an effective supplement to lecture-centered teaching programs. The students obtained more abilities, higher examination scores, and an improved understanding of biomedical information from the Hybrid-PBL program than from conventional teaching methods. Our study was an innovative trial that applied a PBL curriculum to the specific discipline of biochemistry and may provide a potential and promising new teaching method that can be widely utilized. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(4):336-342, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

The biochemistry of hematopoietic stem cell development.

PubMed

Kaimakis, P; Crisan, M; Dzierzak, E

2013-02-01

The cornerstone of the adult hematopoietic system and clinical treatments for blood-related disease is the cohort of hematopoietic stem cells (HSC) that is harbored in the adult bone marrow microenvironment. Interestingly, this cohort of HSCs is generated only during a short window of developmental time. In mammalian embryos, hematopoietic progenitor and HSC generation occurs within several extra- and intraembryonic microenvironments, most notably from 'hemogenic' endothelial cells lining the major vasculature. HSCs are made through a remarkable transdifferentiation of endothelial cells to a hematopoietic fate that is long-lived and self-renewable. Recent studies are beginning to provide an understanding of the biochemical signaling pathways and transcription factors/complexes that promote their generation. The focus of this review is on the biochemistry behind the generation of these potent long-lived self-renewing stem cells of the blood system. Both the intrinsic (master transcription factors) and extrinsic regulators (morphogens and growth factors) that affect the generation, maintenance and expansion of HSCs in the embryo will be discussed. The generation of HSCs is a stepwise process involving many developmental signaling pathways, morphogens and cytokines. Pivotal hematopoietic transcription factors are required for their generation. Interestingly, whereas these factors are necessary for HSC generation, their expression in adult bone marrow HSCs is oftentimes not required. Thus, the biochemistry and molecular regulation of HSC development in the embryo are overlapping, but differ significantly from the regulation of HSCs in the adult. HSC numbers for clinical use are limiting, and despite much research into the molecular basis of HSC regulation in the adult bone marrow, no panel of growth factors, interleukins and/or morphogens has been found to sufficiently increase the number of these important stem cells. An understanding of the biochemistry of HSC

Exploring protein structure and dynamics through a project-oriented biochemistry laboratory module.

PubMed

Lipchock, James M; Ginther, Patrick S; Douglas, Bonnie B; Bird, Kelly E; Patrick Loria, J

2017-09-01

Here, we present a 10-week project-oriented laboratory module designed to provide a course-based undergraduate research experience in biochemistry that emphasizes the importance of biomolecular structure and dynamics in enzyme function. This module explores the impact of mutagenesis on an important active site loop for a biomedically-relevant human enzyme, protein tyrosine phosphatase 1B (PTP1B). Over the course of the semester students guide their own mutant of PTP1B from conception to characterization in a cost-effective manner and gain exposure to fundamental techniques in biochemistry, including site-directed DNA mutagenesis, bacterial recombinant protein expression, affinity column purification, protein quantitation, SDS-PAGE, and enzyme kinetics. This project-based approach allows an instructor to simulate a research setting and prepare students for productive research beyond the classroom. Potential modifications to expand or contract this module are also provided. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(5):403-410, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

Airborne exposure limits for chemical and biological warfare agents: is everything set and clear?

PubMed

Sabelnikov, Alex; Zhukov, Vladimir; Kempf, C Ruth

2006-08-01

Emergency response strategies (guidelines) for biological, chemical, nuclear, or radiological terrorist events should be based on scientifically established exposure limits for all the agents or materials involved. In the case of a radiological terrorist event, emergency response guidelines (ERG) have been worked out. In the case of a terrorist event with the use of chemical warfare (CW) agents the situation is not that clear, though the new guidelines and clean-up values are being generated based on re-evaluation of toxicological and risk data. For biological warfare (BW) agents, such guidelines do not yet exist. In this paper the current status of airborne exposure limits (AELs) for chemical and biological warfare (CBW) agents are reviewed. Particular emphasis is put on BW agents that lack such data. An efficient, temporary solution to bridge the gap in experimental infectious data and to set provisional AELs for BW agents is suggested. It is based on mathematically generated risks of infection for BW agents grouped by their alleged ID50 values in three categories: with low, intermediate and high ID50 values.

Camouflage and Deception Techniques for Urban Warfare

DTIC Science & Technology

1980-10-01

ý 1 97418W / 7. AU"Olil’a) . CONTRACT GA GRANT NUMBER~o) 06. 01911TRMUINORGANIATIOENT NAME AND ADRSS1. RGRMELM ROETTS Cappoulagad forpubl apic ...of air to achieve rigidity as well as~ flotation . lii’ dco br g wohll le iul~lvel iiear real rilbbonl bridlges in order to con1fuse ellicini...A.. (PT. Spain. "~Attackingr and Defending, Populated Places?" Military Review, (October 19414). Felts. Robert. "Urban Warfare. Emerging Material

Thumping the Hive: Russian Neocortical Warfare in Chechnya

DTIC Science & Technology

2004-09-01

against the determined, resourceful Muslim tribes of the mountains and forests of the Central Caucasus, Russia’s military forces compiled a frustrating...warfare against minds and envisioning weapons as any means used to change the enemy’s will.” The merging of these two hemispheric approaches produces... single adviser in the Soviet system 40 Ibid., 5. 41 Szafranski, 409. 19 can allow himself to

Potassium Ferrate: A Novel Chemical Warfare Agent Decontaminant

DTIC Science & Technology

2004-11-16

POTASSIUM FERRATE : A NOVEL CHEMICAL WARFARE AGENT DECONTAMINANT Russell Greene greener@battelle.org (Battelle Memorial Institute, West...difficulties, and/or unsatisfactory CWA destruction efficiencies. Potassium ferrate (K2FeO4) addresses all of these issues through its high oxidation...used and proposed, are unstable (with respect to loss of activity) and/or difficult to prepare, store and transport. Potassium ferrate (K2FeO4) has

Combining content and elements of communication into an upper-level biochemistry course.

PubMed

Whittington, Carli P; Pellock, Samuel J; Cunningham, Rebecca L; Cox, James R

2014-01-01

This report describes how a science communication module was incorporated into an advanced biochemistry course. Elements of communication were taught synergistically with biochemistry content in this course in an effort to expose students to a variety of effective oral communication strategies. Students were trained to use these established techniques and incorporated them into various presentations throughout the course. Three students describe their use of specific resources and how the skills learned relate to their future career. The importance and relevance of science communication are receiving unprecedented national attention. The academic scientific community must respond by incorporating more communication-centered instruction and opportunities in the classroom and laboratory. © 2013 by The International Union of Biochemistry and Molecular Biology.

Teaching biochemistry to medical students in Singapore--from organic chemistry to problem-based learning.

PubMed

Khoo, H E

2005-07-01

The medical faculty in the National University of Singapore started in 1905 but the Chair in Biochemistry was only established in 1927. For many years the biochemistry course consisted of the teaching of the organic chemistry of substances of physiological importance, nutrition, metabolism and hormones. In 1961, clinical biochemistry was introduced and in the 1980s, genetics and molecular biology were included. By then, most of the organic chemistry content had been removed as greater emphasis was placed on clinical correlation. Laboratory classes consisted of mock glucose tolerance tests and the measurement of various enzymes. By the 1990s, students were no longer interested in such practical classes, so a bold decision was made around 1995 to remove laboratory classes from the curriculum. Unfortunately, this meant that the medical students who might have been interested in laboratory work could no longer do such work. However, the new curriculum in 1999 gave the department an opportunity to offer a laboratory course as an elective for interested students. This new curriculum adopted an integrated approach with Genetics being taught as part of Paediatrics, and a new module (Structural and Cell Biology) comprising aspects of cell biology and biochemistry was introduced. This module is currently taught by staff from Anatomy, Physiology and Biochemistry. Some biochemistry content is now incorporated into the clinical problem scenarios of problem-based learning such as jaundice, diabetes mellitus, anorexia nervosa, etc. So the evolution of teaching biochemistry to medical students in Singapore has paralleled worldwide trends and moved from the didactic teaching of organic chemistry of biomolecules to problem-based learning using clinical cases.

Reference intervals for selected serum biochemistry analytes in cheetahs Acinonyx jubatus.

PubMed

Hudson-Lamb, Gavin C; Schoeman, Johan P; Hooijberg, Emma H; Heinrich, Sonja K; Tordiffe, Adrian S W

2016-02-26

Published haematologic and serum biochemistry reference intervals are very scarce for captive cheetahs and even more for free-ranging cheetahs. The current study was performed to establish reference intervals for selected serum biochemistry analytes in cheetahs. Baseline serum biochemistry analytes were analysed from 66 healthy Namibian cheetahs. Samples were collected from 30 captive cheetahs at the AfriCat Foundation and 36 free-ranging cheetahs from central Namibia. The effects of captivity-status, age, sex and haemolysis score on the tested serum analytes were investigated. The biochemistry analytes that were measured were sodium, potassium, magnesium, chloride, urea and creatinine. The 90% confidence interval of the reference limits was obtained using the non-parametric bootstrap method. Reference intervals were preferentially determined by the non-parametric method and were as follows: sodium (128 mmol/L - 166 mmol/L), potassium (3.9 mmol/L - 5.2 mmol/L), magnesium (0.8 mmol/L - 1.2 mmol/L), chloride (97 mmol/L - 130 mmol/L), urea (8.2 mmol/L - 25.1 mmol/L) and creatinine (88 µmol/L - 288 µmol/L). Reference intervals from the current study were compared with International Species Information System values for cheetahs and found to be narrower. Moreover, age, sex and haemolysis score had no significant effect on the serum analytes in this study. Separate reference intervals for captive and free-ranging cheetahs were also determined. Captive cheetahs had higher urea values, most likely due to dietary factors. This study is the first to establish reference intervals for serum biochemistry analytes in cheetahs according to international guidelines. These results can be used for future health and disease assessments in both captive and free-ranging cheetahs.

Prognostication: Do the Services See the Same Future of Warfare?

DTIC Science & Technology

2008-05-01

conduct of war, warfare. 24 Dana Johnson, Scott Pace, C. Bryan Gabbard , Space: Emerging Options for National Power, (RAND, 1998), 10. 25 Creveld, 145...Bryan Gabbard . Space: Emerging Options for National Power, RAND http://www.rand.org/pubs/monograph_reports/MR517/, 1998. (Accessed 5 January 2008

Operational advantages of using Cyber Electronic Warfare (CEW) in the battlefield

NASA Astrophysics Data System (ADS)

Yasar, Nurgul; Yasar, Fatih M.; Topcu, Yucel

2012-06-01

While cyberspace is emerging as a new battlefield, conventional Electronic Warfare (EW) methods and applications are likely to change. Cyber Electronic Warfare (CEW) concept which merges cyberspace capabilities with traditional EW methods, is a new and enhanced form of the electronic attack. In this study, cyberspace domain of the battlefield is emphazised and the feasibility of integrating Cyber Warfare (CW) concept into EW measures is researched. The SWOT (Strengths, Weaknesses, Opportunities and Threats) analysis method is used to state the operational advantages of using CEW concept in the battlefield. The operational advantages of CEW are assessed by means of its effects on adversary air defense systems, communication networks and information systems. Outstanding technological and operational difficulties are pointed out as well. As a result, a comparison of CEW concept and conventional EW applications is presented. It is concluded that, utilization of CEW concept is feasible at the battlefield and it may yield important operational advantages. Even though the computers of developed military systems are less complex than normal computers, they are not subjected to cyber threats since they are closed systems. This concept intends to show that these closed systems are also open to the cyber threats. As a result of the SWOT analysis, CEW concept provides Air Forces to be used in cyber operations effectively. On the other hand, since its Collateral Damage Criteria (CDC) is low, the usage of cyber electronic attack systems seems to grow up.

A Kinetic Experiment for the Biochemistry Laboratory.

ERIC Educational Resources Information Center

Palmer, Richard E.

1986-01-01

Discusses the use of specific reactions of metabolic pathways to make measurements in the laboratory. Describes an adaptation of an experiment used in undergraduate biochemistry laboratories involving the induction of an enzyme in E. coli, as well as its partial purification and characterization. (TW)

Personal protection during resuscitation of casualties contaminated with chemical or biological warfare agents--a survey of medical first responders.

PubMed

Brinker, Andrea; Prior, Kate; Schumacher, Jan

2009-01-01

The threat of mass casualties caused by an unconventional terrorist attack is a challenge for the public health system, with special implications for emergency medicine, anesthesia, and intensive care. Advanced life support of patients injured by chemical or biological warfare agents requires an adequate level of personal protection. The aim of this study was to evaluate the personal protection knowledge of emergency physicians and anesthetists who would be at the frontline of the initial health response to a chemical/biological warfare agent incident. After institutional review board approval, knowledge of personal protection measures among emergency medicine (n = 28) and anesthetics (n = 47) specialty registrars in the South Thames Region of the United Kingdom was surveyed using a standardized questionnaire. Participants were asked for the recommended level of personal protection if a chemical/biological warfare agent(s) casualty required advanced life support in the designated hospital resuscitation area. The best awareness within both groups was regarding severe acute respiratory syndrome, and fair knowledge was found regarding anthrax, plague, Ebola, and smallpox. In both groups, knowledge about personal protection requirements against chemical warfare agents was limited. Knowledge about personal protection measures for biological agents was acceptable, but was limited for chemical warfare agents. The results highlight the need to improve training and education regarding personal protection measures for medical first receivers.

The role of the sand in chemical warfare agent exposure among Persian Gulf War veterans: Al Eskan disease and "dirty dust".

PubMed

Korényi-Both, A L; Svéd, L; Korényi-Both, G E; Juncer, D J; Korényi-Both, A L; Székely, A

2000-05-01

The purpose of this paper is to inquire into the relationship between Al Eskan disease and the probable exposure to chemical warfare agents by Persian Gulf War veterans. Al Eskan disease, first reported in 1991, compromises the body's immunological defense and is a result of the pathogenic properties of the extremely fine, dusty sand located in the central and eastern region of the Arabian peninsula. The disease manifests with localized expression of multisystem disorder. Signs and symptoms of Al Eskan disease have been termed by the news media "Persian Gulf syndrome." The dust becomes a warfare agent when toxic chemicals are microimpregnated into inert particles. The "dirty dust" concept, that the toxicity of an agent could be enhanced by absorption into inactive particles, dates from World War I. A growing body of evidence shows that coalition forces have encountered Iraqi chemical warfare in the theater of operation/Persian Gulf War to a much greater extent than early U.S. Department of Defense information had indicated. Veterans of that war were exposed to chemical warfare agents in the form of direct (deliberate) attacks by chemical weapons, such as missiles and mines, and indirect (accidental) contamination from demolished munition production plants and storage areas, or otherwise. We conclude that the microimpregnated sand particles in the theater of operation/Persian Gulf War depleted the immune system and simultaneously acted as vehicles for low-intensity exposure to chemical warfare agents and had a modifying-intensifying effect on the toxicity of exposed individuals. We recommend recognition of a new term, "dirty sand," as a subcategory of dirty dust/dusty chemical warfare agents. Our ongoing research efforts to investigate the health impact of chemical warfare agent exposure among Persian Gulf War veterans suggest that Al Eskan disease is a plausible and preeminent explanation for the preponderance of Persian Gulf War illnesses.

Correlation of preadmission organic chemistry courses and academic performance in biochemistry at a midwest chiropractic doctoral program.

PubMed

McRae, Marc P

2010-01-01

Organic chemistry has been shown to correlate with academic success in the preclinical years of medicine, dentistry, and graduate physiology. The purpose of this study is to examine the relationship between undergraduate organic chemistry grades and first-semester biochemistry grades at a Midwest chiropractic doctoral program. Students enrolled in a first-semester biochemistry course who had completed the prerequisite courses in organic chemistry offered at this same institution were entered into the study. The total grade for each of the three courses was calculated using the midterm and final exam raw scores with a weighting of 50% each. Analysis consisted of obtaining correlation coefficients between the total grades of organic 1 with biochemistry and organic 2 with biochemistry. Using the biochemistry total grade, the students were divided into quartiles and course grades for both organic chemistry 1 and 2 were calculated. For the 109 students in the study, the correlation coefficient between the biochemistry and organic chemistry 1 and biochemistry and organic chemistry 2 courses was r = 0.744 and r = 0.725, respectively. The difference in organic chemistry grades between those in the first and fourth quartiles was 63.2% and 86.9% for organic chemistry 1 (p < .001) and 60.9% and 79.4% for organic chemistry 2 (p < .001). This study shows that organic chemistry can be used as an indicator of future academic success in a chiropractic biochemistry course. Knowledge of such a relationship could prove useful to identify students who may potentially run into academic difficulty with first-year biochemistry.

A Heuristic Decision Making Model to Mitigate Adverse Consequences in a Network Centric Warfare/Sense and Respond System

DTIC Science & Technology

2005-05-01

made. 4. Do military decision makers identify / analyze adverse consequences presently? Few do based on this research and most don’t do it effectively ...A HEURISTIC DECISION MAKING MODEL TO MITIGATE ADVERSE CONSEQUENCES IN A NETWORK CENTRIC WARFARE / SENSE AND RESPOND SYSTEM...ENS/05-01 A HEURISTIC DECISION MAKING MODEL TO MITIGATE ADVERSE CONSEQUENCES IN A NETWORK CENTRIC WARFARE / SENSE AND RESPOND SYSTEM

Reactivity II: A Second Foundation-Level Course in Integrated Organic, Inorganic, and Biochemistry

ERIC Educational Resources Information Center

Schaller, Chris P.; Graham, Kate J.; McIntee, Edward J.; Jones, T. Nicholas; Johnson, Brian J.

2016-01-01

A foundation-level course is described that integrates material related to reactivity in organic, inorganic, and biochemistry. Designed for second-year students, the course serves majors in chemistry, biochemistry, and biology, as well as prehealth-professions students. Building on an earlier course that developed concepts of nucleophiles and…

Littoral Combat Ship Open Ocean Anti-Submarine Warfare

DTIC Science & Technology

2014-06-01

maintain stealth and its defense in order to properly conduct an attack on a surface vessel (Sternhell and Thorndike 2014, 102). This statement...its target, the surface combatants can counter by increasing their speed (Sternhell and Thorndike 2014). While the maximum speed of the current...120316_PS.pdf Sternhell, Charles M, and Alan M Thorndike . 2014. “Antisubmarine Warfare in World War II.” CNA Analysis & Solutions. Accessed April 14, 2014

Strategic Information Warfare: Challenges for the United States.

DTIC Science & Technology

1998-05-01

Professor Richard H. Shultz Jr. as Director of the International Security Studies Program at the Fletcher School, helped provide both the academic...of Information Warfare and Strategy at National Defense University; and Larry Rothenberg, Institute for Foreign Policy Analysis. Captain Richard P...War in the Information Age" in War in the Information Age. Robert L. Pfaltzgraff, Jr. and Richard P. Shultz, Jr., eds. London: Brassey’s, 1997

Russian and Chinese Information Warfare: Theory and Practice

DTIC Science & Technology

2004-06-01

Integral neurolinguistic programming •Placing essential programs into the conscious or sub- conscious mind •Subconscious suggestions that modify human...Generators of special rays •Optical systems • Neurolinguistic programming •Computer psychotechnology •The mass media •Audiovisual effects •Special effects...Information Warfare: Theory and Practice 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e

Destruction of chemical warfare surrogates using a portable atmospheric pressure plasma jet

NASA Astrophysics Data System (ADS)

Škoro, Nikola; Puač, Nevena; Živković, Suzana; Krstić-Milošević, Dijana; Cvelbar, Uroš; Malović, Gordana; Petrović, Zoran Lj.

2018-01-01

Today's reality is connected with mitigation of threats from the new chemical and biological warfare agents. A novel investigation of cold plasmas in contact with liquids presented in this paper demonstrated that the chemically reactive environment produced by atmospheric pressure plasma jet (APPJ) is potentially capable of rapid destruction of chemical warfare agents in a broad spectrum. The decontamination of three different chemical warfare agent surrogates dissolved in liquid is investigated by using an easily transportable APPJ. The jet is powered by a kHz signal source connected to a low-voltage DC source and with He as working gas. The detailed investigation of electrical properties is performed for various plasmas at different distances from the sample. The measurements of plasma properties in situ are supported by the optical spectrometry measurements, whereas the high performance liquid chromatography measurements before and after the treatment of aqueous solutions of Malathion, Fenitrothion and Dimethyl Methylphosphonate. These solutions are used to evaluate destruction and its efficiency for specific neural agent simulants. The particular removal rates are found to be from 56% up to 96% during 10 min treatment. The data obtained provide basis to evaluate APPJ's efficiency at different operating conditions. The presented results are promising and could be improved with different operating conditions and optimization of the decontamination process.

Thiol biochemistry of prokaryotes

NASA Technical Reports Server (NTRS)

Fahey, Robert C.

1986-01-01

The present studies have shown that GSH metabolism arose in the purple bacteria and cyanobacteria where it functions to protect against oxygen toxicity. Evidence was obtained indicating that GSH metabolism was incorporated into eucaryotes via the endosymbiosis giving rise to mitochrondria and chloroplasts. Aerobic bacteria lacking GSH utilize other thiols for apparently similar functions, the thiol being coenzyme A in Gram positive bacteria and chi-glutamylcysteine in the halobacteria. The thiol biochemistry of prokaryotes is thus seen to be much more highly diversified than that of eucaryotes and much remains to be learned about this subject.

Sink or Swim: The Marine Corps Capacity to Conduct a Marine Expeditionary Brigade Amphibious Assault using Expeditionary Maneuver Warfare

DTIC Science & Technology

2010-03-01

Expeditionary Maneuver Warfare? This study addresses the equipment issues surrounding the Marine expeditionary brigade ’s’ ability to conduct an amphibious...addresses the equipment issues surrounding the expeditionary brigade’s ability to conduct an amphibious assault under expeditionary maneuver warfare in...1 Issues and Elements of the Modern-Day MEB Assault .................................................................. 2 The Marine Corps

[Modeling and implementation method for the automatic biochemistry analyzer control system].

PubMed

Wang, Dong; Ge, Wan-cheng; Song, Chun-lin; Wang, Yun-guang

2009-03-01

In this paper the system structure The automatic biochemistry analyzer is a necessary instrument for clinical diagnostics. First of is analyzed. The system problems description and the fundamental principles for dispatch are brought forward. Then this text puts emphasis on the modeling for the automatic biochemistry analyzer control system. The objects model and the communications model are put forward. Finally, the implementation method is designed. It indicates that the system based on the model has good performance.

Uncovering protein-protein interactions through a team-based undergraduate biochemistry course.

PubMed

Cookmeyer, David L; Winesett, Emily S; Kokona, Bashkim; Huff, Adam R; Aliev, Sabina; Bloch, Noah B; Bulos, Joshua A; Evans, Irene L; Fagre, Christian R; Godbe, Kerilyn N; Khromava, Maryna; Konstantinovsky, Daniel M; Lafrance, Alexander E; Lamacki, Alexandra J; Parry, Robert C; Quinn, Jeanne M; Thurston, Alana M; Tsai, Kathleen J S; Mollo, Aurelio; Cryle, Max J; Fairman, Robert; Charkoudian, Louise K

2017-11-01

How can we provide fertile ground for students to simultaneously explore a breadth of foundational knowledge, develop cross-disciplinary problem-solving skills, gain resiliency, and learn to work as a member of a team? One way is to integrate original research in the context of an undergraduate biochemistry course. In this Community Page, we discuss the development and execution of an interdisciplinary and cross-departmental undergraduate biochemistry laboratory course. We present a template for how a similar course can be replicated at other institutions and provide pedagogical and research results from a sample module in which we challenged our students to study the binding interface between 2 important biosynthetic proteins. Finally, we address the community and invite others to join us in making a larger impact on undergraduate education and the field of biochemistry by coordinating efforts to integrate research and teaching across campuses.

Uncovering protein–protein interactions through a team-based undergraduate biochemistry course

PubMed Central

Cookmeyer, David L.; Winesett, Emily S.; Kokona, Bashkim; Huff, Adam R.; Aliev, Sabina; Bloch, Noah B.; Bulos, Joshua A.; Evans, Irene L.; Fagre, Christian R.; Godbe, Kerilyn N.; Khromava, Maryna; Konstantinovsky, Daniel M.; Lafrance, Alexander E.; Lamacki, Alexandra J.; Parry, Robert C.; Quinn, Jeanne M.; Thurston, Alana M.; Tsai, Kathleen J. S.; Mollo, Aurelio; Cryle, Max J.; Fairman, Robert

2017-01-01

How can we provide fertile ground for students to simultaneously explore a breadth of foundational knowledge, develop cross-disciplinary problem-solving skills, gain resiliency, and learn to work as a member of a team? One way is to integrate original research in the context of an undergraduate biochemistry course. In this Community Page, we discuss the development and execution of an interdisciplinary and cross-departmental undergraduate biochemistry laboratory course. We present a template for how a similar course can be replicated at other institutions and provide pedagogical and research results from a sample module in which we challenged our students to study the binding interface between 2 important biosynthetic proteins. Finally, we address the community and invite others to join us in making a larger impact on undergraduate education and the field of biochemistry by coordinating efforts to integrate research and teaching across campuses. PMID:29091712

An Analysis of the Effectiveness of Analogy Use in College-Level Biochemistry Textbooks

ERIC Educational Resources Information Center

Orgill, MaryKay; Bodner, George M.

2006-01-01

Science instructors and textbook authors often use analogies to help their students use information they already understand to develop an understanding of new concepts. This study reports the results of an analysis of the use of analogies in eight biochemistry textbooks, which included textbooks written for one-semester survey biochemistry courses…

Vertical Integration of Biochemistry and Clinical Medicine Using a Near-Peer Learning Model

ERIC Educational Resources Information Center

Gallan, Alexander J.; Offner, Gwynneth D.; Symes, Karen

2016-01-01

Vertical integration has been extensively implemented across medical school curricula but has not been widely attempted in the field of biochemistry. We describe a novel curricular innovation in which a near-peer learning model was used to implement vertical integration in our medical school biochemistry course. Senior medical students developed…

Assessment of Molecular Construction in Undergraduate Biochemistry

ERIC Educational Resources Information Center

Booth, Deborah; Bateman, Robert C., Jr.; Sirochman, Rudy; Richardson, David C.; Richardson, Jane S.; Weiner, Steven W.; Farwell, Mary; Putnam-Evans, Cindy

2005-01-01

White and group used a two question, open-ended tests to separately evaluate students' learning of specific biochemical concepts in the general biology lecture and laboratory, in the first performance assessment of molecular visualization in teaching biochemistry. Two studies were devoted to protein structure using globins followed by one…

Impact of Virtual Patients as Optional Learning Material in Veterinary Biochemistry Education.

PubMed

Kleinsorgen, Christin; von Köckritz-Blickwede, Maren; Naim, Hassan Y; Branitzki-Heinemann, Katja; Kankofer, Marta; Mándoki, Míra; Adler, Martin; Tipold, Andrea; Ehlers, Jan P

2018-01-01

Biochemistry and physiology teachers from veterinary faculties in Hannover, Budapest, and Lublin prepared innovative, computer-based, integrative clinical case scenarios as optional learning materials for teaching and learning in basic sciences. These learning materials were designed to enhance attention and increase interest and intrinsic motivation for learning, thus strengthening autonomous, active, and self-directed learning. We investigated learning progress and success by administering a pre-test before exposure to the virtual patients (vetVIP) cases, offered vetVIP cases alongside regular biochemistry courses, and then administered a complementary post-test. We analyzed improvement in cohort performance and level of confidence in rating questions. Results of the performance in biochemistry examinations in 2014, 2015, and 2016 were correlated with the use of and performance in vetVIP cases throughout biochemistry courses in Hannover. Surveys of students reflected that interactive cases helped them understand the relevance of basic sciences in veterinary education. Differences between identical pre- and post-tests revealed knowledge improvement (correct answers: +28% in Hannover, +9% in Lublin) and enhanced confidence in decision making ("I don't know" answers: -20% in Hannover, -7.5% in Lublin). High case usage and voluntary participation (use of vetVIP cases in Hannover and Lublin >70%, Budapest <1%; response rates in pre-test 72% and post-test 48%) indicated a good increase in motivation for the subject of biochemistry. Despite increased motivation, there was only a weak correlation between performance in final exams and performance in the vetVIP cases. Case-based e-learning could be extended and generated cases should be shared across veterinary faculties.

Correlation of Preadmission Organic Chemistry Courses and Academic Performance in Biochemistry at a Midwest Chiropractic Doctoral Program*

PubMed Central

McRae, Marc P.

2010-01-01

Purpose: Organic chemistry has been shown to correlate with academic success in the preclinical years of medicine, dentistry, and graduate physiology. The purpose of this study is to examine the relationship between undergraduate organic chemistry grades and first-semester biochemistry grades at a Midwest chiropractic doctoral program. Methods: Students enrolled in a first-semester biochemistry course who had completed the prerequisite courses in organic chemistry offered at this same institution were entered into the study. The total grade for each of the three courses was calculated using the midterm and final exam raw scores with a weighting of 50% each. Analysis consisted of obtaining correlation coefficients between the total grades of organic 1 with biochemistry and organic 2 with biochemistry. Using the biochemistry total grade, the students were divided into quartiles and course grades for both organic chemistry 1 and 2 were calculated. Results: For the 109 students in the study, the correlation coefficient between the biochemistry and organic chemistry 1 and biochemistry and organic chemistry 2 courses was r = 0.744 and r = 0.725, respectively. The difference in organic chemistry grades between those in the first and fourth quartiles was 63.2% and 86.9% for organic chemistry 1 (p < .001) and 60.9% and 79.4% for organic chemistry 2 (p < .001). Conclusion: This study shows that organic chemistry can be used as an indicator of future academic success in a chiropractic biochemistry course. Knowledge of such a relationship could prove useful to identify students who may potentially run into academic difficulty with first-year biochemistry PMID:20480012

Unmanned Warfare: Second and Third Order Effects Stemming from the Afghan Operational Environment between 2001 and 2010

DTIC Science & Technology

2011-06-10

the very nature of warfare took a dramatic step into the future. With new assets capable of remaining airborne for nearly 24 hours and live video ...warfare took a dramatic step into the future. With new assets capable of remaining airborne for nearly 24 hours and live video feeds streaming to...shape the battlefield during protracted combat operations. From the real time video feeds, to the 24 hour coverage of an area of interest, tangible

Biochemistry Instructors' Views toward Developing and Assessing Visual Literacy in Their Courses

ERIC Educational Resources Information Center

Linenberger, Kimberly J.; Holme, Thomas A.

2015-01-01

Biochemistry instructors are inundated with various representations from which to choose to depict biochemical phenomena. Because of the immense amount of visual know-how needed to be an expert biochemist in the 21st century, there have been calls for instructors to develop biochemistry students' visual literacy. However, visual literacy has…

Incorporation of Ethical and Societal Issues in Biochemistry into a Senior Seminar Course

ERIC Educational Resources Information Center

Caspers, Mary Lou; Roberts-Kirchhoff, Elizabeth S.

2003-01-01

In their senior year, biochemistry majors at the University of Detroit Mercy take a senior seminar course entitled "Recent Advances in Biochemistry Related to Societal Issues." Students read papers selected from the current literature and take turns presenting these papers to the class. Papers are grouped into units dealing with molecular biology,…

Introduction to electronic warfare

NASA Astrophysics Data System (ADS)

Schleher, D. C.

A broad overview of electronic warfare (EW) is given, emphasizing radar-related EW applications. A broad perspective of the EW field is first given, defining EW terms and giving methods of EW threat analysis and simulation. Electronic support measures and electronic countermeasures (ECM) systems are described, stressing their application to radar EW. Radars are comprehensively discussed from a system viewpoint with emphasis on their application in weapon systems and their electronic counter-countermeasures capabilities. Some general topics in C3 systems are described, stressing communication systems, C3I systems, and air defense systems. Performance calculations for EW and radar systems are covered, and modern EW signal processing is described from an airborne ECM perspective. Future trends and technology in the EW world are considered, discussing such topics as millimeter-wave EW, low-observable EW technology, GaAs monolithic circuits, VHSIC, and AI.

Just War and Postmodern Warfare: A German Case Study

DTIC Science & Technology

2015-04-01

warfare construct, Germany is shaping a military concept based on recent conflicts and unfettered by biases of conventional strategies, organizations...remain sovereign while subconsciously evolving toward liberal democratic ideas. In respecting each country’s political sensitivities, Germany’s...before exhausting all diplomatic, economic and information instruments. Whereas the term AU/ACSC/PINSON/AY15 13 “interests” may bias the United

Unconventional Warfare and Counterinsurgency in Pakistan: A Brief History

DTIC Science & Technology

2012-11-01

inter-connected. Punjabi Pakistani militants with sophisticated asymmetric warfare training and experience fighting Indian forces in Kashmir...factions. These Punjabi Pakistani militants would prove to be some of the most dangerous opponents of the government after 2006. From 2003 to 2006, the...68 Khan. “Untangling the Punjabi Taliban Network”. CTC Sentinel, March 2010; Franco, “Tehrik-e-Taliban Pakistan.” 69 Iqbal

Modeling the transport of chemical warfare agents and simulants in polymeric substrates for reactive decontamination

NASA Astrophysics Data System (ADS)

Pearl, Thomas; Mantooth, Brent; Varady, Mark; Willis, Matthew

2014-03-01

Chemical warfare agent simulants are often used for environmental testing in place of highly toxic agents. This work sets the foundation for modeling decontamination of absorbing polymeric materials with the focus on determining relationships between agents and simulants. The correlations of agents to simulants must consider the three way interactions in the chemical-material-decontaminant system where transport and reaction occur in polymer materials. To this end, diffusion modeling of the subsurface transport of simulants and live chemical warfare agents was conducted for various polymer systems (e.g., paint coatings) with and without reaction pathways with applied decontamination. The models utilized 1D and 2D finite difference diffusion and reaction models to simulate absorption and reaction in the polymers, and subsequent flux of the chemicals out of the polymers. Experimental data including vapor flux measurements and dynamic contact angle measurements were used to determine model input parameters. Through modeling, an understanding of the relationship of simulant to live chemical warfare agent was established, focusing on vapor emission of agents and simulants from materials.

Textbook of Military Medicine. Part 1. Warfare, Weaponry, and the Casualty. Part 5. Conventional Warfare. Ballistic, Blast, and Burn Injuries

DTIC Science & Technology

1991-01-01

United States. Because the vast majority of our patients are not active -duty military personnel, it may seem that our day-to-day ac- tivities are far... activated . A designated time-delay fuse uses an Source: Reference 8 15 Conventional Warfare: Ballistic, Blast, and Burn Injuries explosion and the...be found embedded and unexploded in tissue. The fuse is located at the tip of the warhead, and is activated and will deionate on contact only after

The Venus "Shell-over-Star" hieroglyph and Maya warfare: An examination of the interpretation of a Mayan symbol

NASA Astrophysics Data System (ADS)

Voit, Claudia Ann

For decades, Maya scholars have associated the Mayan "Shell-Star" (also referred to as "Star-War") hieroglyph with Maya warfare. Put forward by scholars such as Floyd Lounsbury and David Kelley, and later advanced by Linda Schele, David Freidel, Ian Graham, Peter Matthews, Anthony Aveni and others, there are now dozens of published articles and chapters relating the hieroglyph to Venus and warfare. Venus is one of the most notable celestial objects outside of the Sun and Moon and was highly visible to the inhabitants of the Maya world. The Dresden Codex (an astronomical almanac) contains important information about the planet Venus, and the calendar section was deciphered by the librarian and mathematician, Ernst Förstemann in the late 1800s. In his decipherment, he deduced that the numbers contained in the tables must be connected to the orbital period of the planet. There is no other planet with the same orbital period 3 as Venus. Förstemann suggested that the decoded astronomy tables were used by the Maya to determine when to wage war. This interpretation, along with others, like Floyd Lounsbury`s study of Venus and the Long Count date at Bonampak were the seeds that have led to methodological errors that first began to take root in Maya research. The idea of the Venus association with warfare took hold and continues to propagate. Many scholars continue to assert that the "shell-star" glyph is related to warfare events. Others, like Gerardo Aldana, and Stanley Guenter, have recently come forward to reexamine and question the hieroglyph and its relationship, if any, to Maya warfare. I suggest, further, that methodological errors may have occurred along the way. I propose that these errors include data lost in translation, and inaccurate translations. In addition, the statistical analysis of Venus cycles has weak points. If this identification of the errors is correct, we need to re-evaluate the weakened foundation on which we are building our assertions about

Stormy Waters: Technology, Sea Control and Regional Warfare

DTIC Science & Technology

1994-06-01

AD-A283 945 NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA "DTIC TI ELECTETHESIS • S Sop()z 994 v G STOwM NATERS "T"CDOLOGY, SEA CNTROL AND REGIONAL... S . FUNDING NUMBERS Stormy Waters: Technology, Sea Control and Regional Warfare 6. AUTHOR( S ) David A. Schnell 7. PERFORMING ORGANIZATION NAME( S ) AND...ADDRESSRES) 8. PERFORMING ORGANIZATION Naval Postgraduate School REPORT NUMBER Monterey, CA 93943-5000 9. SPONSORING/MONITORING AGENCY NAME( S ) AND

WASTE MINIZATION OPPORTUNITY ASSESSMENT: NAVAL UNDERSEA WARFARE ENGINEERING STATION - KEYPORT, WA

EPA Science Inventory

This report describes the application of EPA's waste minimization assessment procedures to a torpedo maintenance facility at the Naval Undersea Warfare Engineering Station, Keyport, WA. he assessment focused on the Mark 48 shop and the Mark 46 shop. hese shops service the Mark 48...

Destruction of chemical warfare agents using metal-organic frameworks

NASA Astrophysics Data System (ADS)

Mondloch, Joseph E.; Katz, Michael J.; Isley, William C., III; Ghosh, Pritha; Liao, Peilin; Bury, Wojciech; Wagner, George W.; Hall, Morgan G.; Decoste, Jared B.; Peterson, Gregory W.; Snurr, Randall Q.; Cramer, Christopher J.; Hupp, Joseph T.; Farha, Omar K.

2015-05-01

Chemical warfare agents containing phosphonate ester bonds are among the most toxic chemicals known to mankind. Recent global military events, such as the conflict and disarmament in Syria, have brought into focus the need to find effective strategies for the rapid destruction of these banned chemicals. Solutions are needed for immediate personal protection (for example, the filtration and catalytic destruction of airborne versions of agents), bulk destruction of chemical weapon stockpiles, protection (via coating) of clothing, equipment and buildings, and containment of agent spills. Solid heterogeneous materials such as modified activated carbon or metal oxides exhibit many desirable characteristics for the destruction of chemical warfare agents. However, low sorptive capacities, low effective active site loadings, deactivation of the active site, slow degradation kinetics, and/or a lack of tailorability offer significant room for improvement in these materials. Here, we report a carefully chosen metal-organic framework (MOF) material featuring high porosity and exceptional chemical stability that is extraordinarily effective for the degradation of nerve agents and their simulants. Experimental and computational evidence points to Lewis-acidic ZrIV ions as the active sites and to their superb accessibility as a defining element of their efficacy.

Destruction of chemical warfare agents using metal-organic frameworks.

PubMed

Mondloch, Joseph E; Katz, Michael J; Isley, William C; Ghosh, Pritha; Liao, Peilin; Bury, Wojciech; Wagner, George W; Hall, Morgan G; DeCoste, Jared B; Peterson, Gregory W; Snurr, Randall Q; Cramer, Christopher J; Hupp, Joseph T; Farha, Omar K

2015-05-01

Chemical warfare agents containing phosphonate ester bonds are among the most toxic chemicals known to mankind. Recent global military events, such as the conflict and disarmament in Syria, have brought into focus the need to find effective strategies for the rapid destruction of these banned chemicals. Solutions are needed for immediate personal protection (for example, the filtration and catalytic destruction of airborne versions of agents), bulk destruction of chemical weapon stockpiles, protection (via coating) of clothing, equipment and buildings, and containment of agent spills. Solid heterogeneous materials such as modified activated carbon or metal oxides exhibit many desirable characteristics for the destruction of chemical warfare agents. However, low sorptive capacities, low effective active site loadings, deactivation of the active site, slow degradation kinetics, and/or a lack of tailorability offer significant room for improvement in these materials. Here, we report a carefully chosen metal-organic framework (MOF) material featuring high porosity and exceptional chemical stability that is extraordinarily effective for the degradation of nerve agents and their simulants. Experimental and computational evidence points to Lewis-acidic Zr(IV) ions as the active sites and to their superb accessibility as a defining element of their efficacy.

International Environmental Law and Biochemistry: An Innovative Teaching Opportunity.

ERIC Educational Resources Information Center

Candlish, John

1998-01-01

Explores the ties between international environmental law and biochemistry with respect to genetically modified organisms, biodiversity, marine pollution, cancer biology, and pesticide contamination of food. Contains 30 references. (DDR)

Continuous Acoustic Sensing With an Unmanned Aerial Vehicle System for Anti-Submarine Warfare in a High-Threat Area

DTIC Science & Technology

2015-12-01

strive in multiple warfare areas. This research benefits not only the Navy, through enhancement of offensive warfighting by testing the next...multiple warfare areas. This research benefits not only the Navy, through enhancement of offensive warfighting by testing the next generation of...produce and definitely worth the research and testing to be a positive asset for the Navy. It not only can stay on station for an exponential amount of

Winning the Counterinsurgency Fight in Iraq: The Role of Political Culture in Counterinsurgency Warfare 2003-2006 in Iraq

DTIC Science & Technology

2006-05-26

Winning the Counterinsurgency Fight in Iraq: The Role of Political Culture in Counterinsurgency Warfare 2003-2006 in Iraq A Monograph by Major...Counterinsurgency Fight in Iraq: The Role of Political Culture in Counterinsurgency Warfare 2003-2006 in Iraq 5c. PROGRAM ELEMENT NUMBER 5d. PROJECT NUMBER 5e...14. ABSTRACT This monograph provides insight into the importance of political culture in relation to developing a counterinsurgency strategy. This

Space and Naval Warfare Systems Command and Overall Navy Needs to Improve Management of Waiver and Deferral Requests

DTIC Science & Technology

2015-10-08

Management of Waiver and Deferral Requests Visit us at www.dodig.mil Objective Our objective for this audit was to evaluate the Space and Naval Warfare...We conducted this audit in accordance with generally accepted government auditing standards. We considered management comments on a draft of...OFFICIAL USE ON Y Introduction DODIG-2016-003 │ 1 Introduction Objective Our objective for this audit was to evaluate the Space and Naval Warfare

Feasibility Study for the Use of Green, Bio-Based, Efficient Reactive Sorbent Material to Neutralize Chemical Warfare Agents

DTIC Science & Technology

2012-08-02

REPORT Feasibility study for the use of green, bio-based, efficient reactive sorbent material to neutralize chemical warfare agents 14. ABSTRACT 16...way cellulose, lignin and hemicelluloses interact as well as whole wood dissolution occurs in ILs. The present project was conducted to 1. REPORT...Feasibility study for the use of green, bio-based, efficient reactive sorbent material to neutralize chemical warfare agents Report Title ABSTRACT Over the

Lanchester-Type Models of Warfare. Volume I

DTIC Science & Technology

1980-10-01

1 / - -I SLEVEL 0 LANCHESTER-TYPE MODELS OF WARFARE VOLUME I$ by James G. Taylor Professor of Operations Research Naval Postgraduate School Monterey...California a DTIC¢-• 1 tELECTED S• OCT 28 1980 • D bFiFTr--••5i•:hii:rfl 8 00 O 20 01 9 Approved for public 8e0 -.;209-’ )Distribution Unlimited KL...34’:•-~ l,,, I " .. .. .. . . .. ... , . . , • •_. . .• .: _ - •’ .. - ..A ] . ......LJ- srcr.’NTY CL ASS 1CATl.,N OF’ TNH 4 a. , 1 A t HI At) IN .TWV

Recognizing and Adapting to Unrestricted Warfare Practices by China

DTIC Science & Technology

2012-02-15

Sun Zi, are of particular significance. These men taught obedience to the state, the primacy of relationships over law, and the importance of...Von Clausewitz and Baron Antoine Jomini. Whereas Clausewitz provided a theoretical strategic framework for warfare where “war is a continuation of...of family (filial Piety), ritual, loyalty, meritocracy, relationships , and the desire to avoid shame and losing face.17 Chinese rulers often used

TDPAC and β-NMR applications in chemistry and biochemistry

NASA Astrophysics Data System (ADS)

Jancso, Attila; Correia, Joao G.; Gottberg, Alexander; Schell, Juliana; Stachura, Monika; Szunyogh, Dániel; Pallada, Stavroula; Lupascu, Doru C.; Kowalska, Magdalena; Hemmingsen, Lars

2017-06-01

Time differential perturbed angular correlation (TDPAC) of γ-rays spectroscopy has been applied in chemistry and biochemistry for decades. Herein we aim to present a comprehensive review of chemical and biochemical applications of TDPAC spectroscopy conducted at ISOLDE over the past 15 years, including elucidation of metal site structure and dynamics in proteins and model systems. β-NMR spectroscopy is well established in nuclear physics, solid state physics, and materials science, but only a limited number of applications in chemistry have appeared. Current endeavors at ISOLDE advancing applications of β-NMR towards chemistry and biochemistry are presented, including the first experiment on 31Mg2+ in an ionic liquid solution. Both techniques require the production of radioisotopes combined with advanced spectroscopic instrumentation present at ISOLDE.

Health-related quality of life of chemical warfare victims: an assessment with the use of a specific tool.

PubMed

Biat Saeed, Khaled; Parandeh, Akram; Alhani, Fatemeh; Salaree, Mohammad Mehdi

2014-02-01

Exposure to chemical warfare gases significantly changes the quality of life (QoL) of victims and has significant chronic adverse effects. This study sought to assess the health-related QoL (HRQoL) of chemical victims by means of a tool specifically designed for this purpose. The correlation of their QoL with several demographic factors was evaluated as well. In this descriptive cross-sectional study, 120 chemical warfare victims were selected from subjects presenting to selected medical centers in Tehran in 2012 using convenience sampling. Two questionnaires of demographic information and HRQoL of chemical warfare victims (specific tool) were used for data collection. The data were analyzed using SPSS version 20 software (IBM, Armonk, NY, USA). The mean and standard deviation (mean ± SD) of scores obtained by chemical warfare victims in physical, psychosocial and spiritual domains was 39.6 ± 16.5, 42.1 ± 15.2 and 82.4 ± 15.4, respectively. Different age groups showed a significant difference in the psychosocial domain score (P < 0.01). Also, the physical and spiritual domain scores had significant differences with respect to the level of education (P < 0.001). The occupational status showed significant differences in the psychosocial and spiritual domains scores of QoL (P < 0.001). The physical and psychosocial domain scores also accounted for a significant difference with respect to the duration and severity of pulmonary symptoms (P < 0.05). Considering the importance and high value of spirituality in chemical warfare victims, it can be used as strategically for these patients to help them cope with their injury and improve their physical and psychosocial health and QoL.

Proximal detection of chemical warfare agents using PMIRRAS

NASA Astrophysics Data System (ADS)

Petryk, Michael W. P.; Marenco, Armando J.

2010-04-01

Non-contact chemical warfare agent detection has been demonstrated on military painted surfaces using polarization modulation infrared reflection-absorption spectroscopy (PMIRRAS). Notably, VX has been detected on chemical agent resistance coating (CARC) paint at a distance of approximately 10 cm. PMIRRAS does not rely on the presence of chemical vapors and is not affected by many common battlefield interferants such as aerosolized dust, water and diesel vapors, etc., making it highly suitable for use in operational environments.

Positron Emission Tomography: Human Brain Function and Biochemistry.

ERIC Educational Resources Information Center

Phelps, Michael E.; Mazziotta, John C.

1985-01-01

Describes the method, present status, and application of positron emission tomography (PET), an analytical imaging technique for "in vivo" measurements of the anatomical distribution and rates of specific biochemical reactions. Measurements and image dynamic biochemistry link basic and clinical neurosciences with clinical findings…

The Future Russian Navy: Interests of the Military

DTIC Science & Technology

1993-05-01

plasma, pulse, membrane, biochemistry , and radiology.’𔃿 Soviet science had to discover and apply "as yet unknown properties of matter, natural laws...agree that large armored forces have become " dinosaurs " in modern warfare.1 Second, all parties agree that the Russian armed forces must be smaller

Factors Affecting the Retention Decisions of Female Surface Warfare Officers

DTIC Science & Technology

2003-03-01

NAVAL POSTGRADUATE SCHOOL Monterey, California THESIS Approved for public release; distribution is unlimited. FACTORS AFFECTING THE RETENTION...Warfare Officers 6. AUTHOR(S) Clifton, Elizabeth A. 5. FUNDING NUMBERS 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School ...for the degree of MASTER OF SCIENCE IN LEADERSHIP AND HUMAN RESOURCE DEVELOPMENT from the NAVAL POSTGRADUATE SCHOOL March 2003

MOFwich: Sandwiched Metal-Organic Framework-Containing Mixed Matrix Composites for Chemical Warfare Agent Removal.

PubMed

Peterson, Gregory W; Lu, Annie X; Hall, Morgan G; Browe, Matthew A; Tovar, Trenton; Epps, Thomas H

2018-02-28

This work describes a new strategy for fabricating mixed matrix composites containing layered metal-organic framework (MOF)/polymer films as functional barriers for chemical warfare agent protection. Through the use of mechanically robust polymers as the top and bottom encasing layers, a high-MOF-loading, high-performance-core layer can be sandwiched within. We term this multifunctional composite "MOFwich". We found that the use of elastomeric encasing layers enabled core layer reformation after breakage, an important feature for composites and membranes alike. The incorporation of MOFs into the core layer led to enhanced removal of chemical warfare agents while simultaneously promoting moisture vapor transport through the composite, showcasing the promise of these composites for protection applications.

Developing and Supporting Students' Autonomy to Plan, Perform, and Interpret Inquiry-Based Biochemistry Experiments

ERIC Educational Resources Information Center

Silva, Thanuci; Galembeck, Eduardo

2017-01-01

Laboratory sessions are designed to develop the experimental skills and the acquaintance with instruments that may contribute to a successful career in Biochemistry and associated fields. This study is a report on improving a traditional Biochemistry course by devising the laboratory sessions as an inquiry-based environment to develop the…

75 FR 8147 - Notice of Consideration of Amendment Request for Decommissioning of Analytical Bio-Chemistry...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

... NUCLEAR REGULATORY COMMISSION [Docket No. 030-05154; NRC-2010-0056] Notice of Consideration of Amendment Request for Decommissioning of Analytical Bio-Chemistry Laboratories, Inc. Sanitary Lagoon... license amendment to Byproduct Material License No. 24- 13365-01 issued to Analytical Bio-Chemistry...

A Problem-Based Learning Design for Teaching Biochemistry.

ERIC Educational Resources Information Center

Dods, Richard F.

1996-01-01

Describes the design of a biochemistry course that uses problem-based learning. Provides opportunities for students to question, dispute, confirm, and disconfirm their understanding of basic concepts. Emphasizes self-correction through dialogue. Topics covered include amino acids, metabolic pathways and inherited disease, proteins, enzymes and…

Baseline hematology and serum biochemistry results for Indian leopards (Panthera pardus fusca)

PubMed Central

Shanmugam, Arun Attur; Muliya, Sanath Krishna; Deshmukh, Ajay; Suresh, Sujay; Nath, Anukul; Kalaignan, Pa; Venkataravanappa, Manjunath; Jose, Lyju

2017-01-01

Aim: The aim of the study was to establish the baseline hematology and serum biochemistry values for Indian leopards (Panthera pardus fusca), and to assess the possible variations in these parameters based on age and gender. Materials and Methods: Hemato-biochemical test reports from a total of 83 healthy leopards, carried out as part of routine health evaluation in Bannerghatta Biological Park and Manikdoh Leopard Rescue Center, were used to establish baseline hematology and serum biochemistry parameters for the subspecies. The hematological parameters considered for the analysis included hemoglobin (Hb), packed cell volume, total erythrocyte count (TEC), total leukocyte count (TLC), mean corpuscular volume (MCV), mean corpuscular Hb (MCH), and MCH concentration. The serum biochemistry parameters considered included total protein (TP), albumin, globulin, aspartate aminotransferase, alanine aminotransferase (ALT), blood urea nitrogen, creatinine, triglycerides, calcium, and phosphorus. Results: Even though few differences were observed in hematologic and biochemistry values between male and female Indian leopards, the differences were statistically not significant. Effects of age, however, were evident in relation to many hematologic and biochemical parameters. Sub-adults had significantly greater values for Hb, TEC, and TLC compared to adults and geriatric group, whereas they had significantly lower MCV and MCH compared to adults and geriatric group. Among, serum biochemistry parameters the sub-adult age group was observed to have significantly lower values for TP and ALT than adult and geriatric leopards. Conclusion: The study provides a comprehensive analysis of hematologic and biochemical parameters for Indian leopards. Baselines established here will permit better captive management of the subspecies, serve as a guide to assess the health and physiological status of the free ranging leopards, and may contribute valuable information for making effective

Teaching Arrangements of Carbohydrate Metabolism in Biochemistry Curriculum in Peking University Health Science Center

ERIC Educational Resources Information Center

Chen, Hao; Ni, Ju-Hua

2013-01-01

Biochemistry occupies a unique place in the medical school curricula, but the teaching of biochemistry presents certain challenges. One of these challenges is facilitating students' interest in and mastery of metabolism. The many pathways and modes of regulation can be overwhelming for students to learn and difficult for professors to teach in an…

Conflict Without Casualties: Non-Lethal Weapons in Irregular Warfare

DTIC Science & Technology

2007-09-01

the body,” and the Geneva Protocol of 1925, bans the use of chemical and biological weapons .11 On 8 April 1975, President Ford issued Executive...E Funding – PE 63851M) (accessed 15 December 2006). The American Journal of Bioethics . “Medical Ethics and Non-Lethal Weapons .” Bioethics.net...CASUALTIES: NON-LETHAL WEAPONS IN IRREGULAR WARFARE by Richard L. Scott September 2007 Thesis Advisor: Robert McNab Second Reader

U.S. Army Special Forces Roles in Asymmetric Warfare

DTIC Science & Technology

2001-06-01

1Jonathan B . Tucker, “Asymmetric Warfare: An Emerging Threat to U.S. Security,” Forum For Applied Research and Public Policy (Monterey...8Ibid., 34. 9Tucker, 11. 10Ibid., 2. 11 Henry H . Shelton, GEN, USA, Commander in Chief, U.S. Special Operations Command...the Senate Armed Services Committee, “Military Threats and Security Challenges Through 2015,” (Washington: 3 February 2000), 3. 26GEN Henry H

Divisional Electronic Warfare Combat (DEWCOM) Model - User Manual.

DTIC Science & Technology

1980-09-01

ulated combat hours. DTIC TA% 1~ Il m I UNCLASSIFIED SIECURITY CLASSIFICATION Or THIS PAGEft7n Date Entered) 4 ’ ./ .7"* t l DIVISIONAL ELECTRONIC WARFARE...277 4.2.1 Report M (Unit Status) ....... .......................... 277 4.2.2 Report M2 (Link Status...NONE in the first 4 spaces. 27 Mai -RF DEWCOM M S aoNE_ DAF INPUT DATA PREPARATI toI 2 4 . 8 1() 1 12 ,1 14 15 1 1718 lq2n2122 21242526 2728293031 3233

Approaches to enhance the teaching quality of experimental biochemistry for MBBS students in TSMU, China.

PubMed

Yu, Lijuan; Yi, Shuying; Zhai, Jing; Wang, Zhaojin

2017-07-08

With the internationalization of medical education in China, the importance of international students' education in medical schools is also increasing. Except foreign students majoring in Chinese language, English Bachelor of Medicine, Bachelor of Surgery (MBSS) students are the largest group of international students. Based on problems in the teaching process for experimental biochemistry, we designed teaching models adapted to the background of international students and strengthened teachers' teaching ability at Taishan Medical University. Several approaches were used in combination to promote teaching effects and increase the benefit of teaching to teachers. The primary data showed an increased passion for basic medical biochemistry and an improved theoretical background for MBSS students, which will be helpful for their later clinical medicine studies. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(4):360-364, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

Essential concepts and underlying theories from physics, chemistry, and mathematics for "biochemistry and molecular biology" majors.

PubMed

Wright, Ann; Provost, Joseph; Roecklein-Canfield, Jennifer A; Bell, Ellis

2013-01-01

Over the past two years, through an NSF RCN UBE grant, the ASBMB has held regional workshops for faculty members from around the country. The workshops have focused on developing lists of Core Principles or Foundational Concepts in Biochemistry and Molecular Biology, a list of foundational skills, and foundational concepts from Physics, Chemistry, and Mathematics that all Biochemistry or Molecular Biology majors must understand to complete their major coursework. The allied fields working group created a survey to validate foundational concepts from Physics, Chemistry, and Mathematics identified from participant feedback at various workshops. One-hundred twenty participants responded to the survey and 68% of the respondents answered yes to the question: "We have identified the following as the core concepts and underlying theories from Physics, Chemistry, and Mathematics that Biochemistry majors or Molecular Biology majors need to understand after they complete their major courses: 1) mechanical concepts from Physics, 2) energy and thermodynamic concepts from Physics, 3) critical concepts of structure from chemistry, 4) critical concepts of reactions from Chemistry, and 5) essential Mathematics. In your opinion, is the above list complete?" Respondents also delineated subcategories they felt should be included in these broad categories. From the results of the survey and this analysis the allied fields working group constructed a consensus list of allied fields concepts, which will help inform Biochemistry and Molecular Biology educators when considering the ASBMB recommended curriculum for Biochemistry or Molecular Biology majors and in the development of appropriate assessment tools to gauge student understanding of how these concepts relate to biochemistry and molecular biology. © 2013 by The International Union of Biochemistry and Molecular Biology.

Above the Influence: The Strategic Effects of Airpower in Irregular Warfare

DTIC Science & Technology

2010-06-01

INDOCHINA. . . . . . . . . . . . . . . . . . . . . 105 APPENDIX B: MAP OF LAOS . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 APPENDIX...perspectives. These perspectives involve the use of airpower in North Vietnam, South Vietnam, and Laos . The overarching political endstate or...Nagl, ―Principles, Imperatives, and Paradoxes of Counterinsurgency,‖ 50; Mao Tse -Tung, Problems of Strategy in Guerrilla Warfare, 215-216; Gray

Using Augmented Reality to Teach and Learn Biochemistry

ERIC Educational Resources Information Center

Vega Garzón, Juan Carlos; Magrini, Marcio Luiz; Galembeck, Eduardo

2017-01-01

Understanding metabolism and metabolic pathways constitutes one of the central aims for students of biological sciences. Learning metabolic pathways should be focused on the understanding of general concepts and core principles. New technologies such Augmented Reality (AR) have shown potential to improve assimilation of biochemistry abstract…

Health-Related Quality of Life of Chemical Warfare Victims: An Assessment with the Use of a Specific Tool

PubMed Central

Biat Saeed, Khaled; Parandeh, Akram; Alhani, Fatemeh; Salaree, Mohammad Mehdi

2014-01-01

Background: Exposure to chemical warfare gases significantly changes the quality of life (QoL) of victims and has significant chronic adverse effects. Objective: This study sought to assess the health-related QoL (HRQoL) of chemical victims by means of a tool specifically designed for this purpose. The correlation of their QoL with several demographic factors was evaluated as well. Patients and Methods: In this descriptive cross-sectional study, 120 chemical warfare victims were selected from subjects presenting to selected medical centers in Tehran in 2012 using convenience sampling. Two questionnaires of demographic information and HRQoL of chemical warfare victims (specific tool) were used for data collection. The data were analyzed using SPSS version 20 software (IBM, Armonk, NY, USA). Results: The mean and standard deviation (mean ± SD) of scores obtained by chemical warfare victims in physical, psychosocial and spiritual domains was 39.6 ± 16.5, 42.1 ± 15.2 and 82.4 ± 15.4, respectively. Different age groups showed a significant difference in the psychosocial domain score (P < 0.01). Also, the physical and spiritual domain scores had significant differences with respect to the level of education (P < 0.001). The occupational status showed significant differences in the psychosocial and spiritual domains scores of QoL (P < 0.001). The physical and psychosocial domain scores also accounted for a significant difference with respect to the duration and severity of pulmonary symptoms (P < 0.05). Conclusions: Considering the importance and high value of spirituality in chemical warfare victims, it can be used as strategically for these patients to help them cope with their injury and improve their physical and psychosocial health and QoL. PMID:24719824

[Decontamination of chemical and biological warfare agents].

PubMed

Seto, Yasuo

2009-01-01

Chemical and biological warfare agents (CBWA's) are diverse in nature; volatile acute low-molecular-weight toxic compounds, chemical warfare agents (CWA's, gaseous choking and blood agents, volatile nerve gases and blister agents, nonvolatile vomit agents and lacrymators), biological toxins (nonvolatile low-molecular-weight toxins, proteinous toxins) and microbes (bacteria, viruses, rickettsiae). In the consequence management against chemical and biological terrorism, speedy decontamination of victims, facilities and equipment is required for the minimization of the damage. In the present situation, washing victims and contaminated materials with large volumes of water is the basic way, and additionally hypochlorite salt solution is used for decomposition of CWA's. However, it still remains unsolved how to dispose large volumes of waste water, and the decontamination reagents have serious limitation of high toxicity, despoiling nature against the environments, long finishing time and non-durability in effective decontamination. Namely, the existing decontamination system is not effective, nonspecifically affecting the surrounding non-target materials. Therefore, it is the urgent matter to build up the usable decontamination system surpassing the present technologies. The symposiast presents the on-going joint project of research and development of the novel decontamination system against CBWA's, in the purpose of realizing nontoxic, fast, specific, effective and economical terrorism on-site decontamination. The projects consists of (1) establishment of the decontamination evaluation methods and verification of the existing technologies and adaptation of bacterial organophosphorus hydrolase, (2) development of adsorptive elimination technologies using molecular recognition tools, and (4) development of deactivation technologies using photocatalysis.

Common student misconceptions in exercise physiology and biochemistry.

PubMed

Morton, James P; Doran, Dominic A; Maclaren, Don P M

2008-06-01

The present study represents a preliminary investigation designed to identify common misconceptions in students' understanding of physiological and biochemical topics within the academic domain of sport and exercise sciences. A specifically designed misconception inventory (consisting of 10 multiple-choice questions) was administered to a cohort of level 1, 2, and 3 undergraduate students enrolled in physiology and biochemistry-related modules of the BSc Sport Science degree at the authors' institute. Of the 10 misconceptions proposed by the authors, 9 misconceptions were confirmed. Of these nine misconceptions, only one misconception appeared to have been alleviated by the current teaching strategy employed during the progression from level 1 to 3 study. The remaining eight misconceptions prevailed throughout the course of the degree program, suggesting that students enter and leave university with the same misconceptions in certain areas of exercise physiology and biochemistry. The possible origins of these misconceptions are discussed, as are potential teaching strategies to prevent and/or remediate them for future years.

Teaching foundational topics and scientific skills in biochemistry within the conceptual framework of HIV protease.

PubMed

Johnson, R Jeremy

2014-01-01

HIV protease has served as a model protein for understanding protein structure, enzyme kinetics, structure-based drug design, and protein evolution. Inhibitors of HIV protease are also an essential part of effective HIV/AIDS treatment and have provided great societal benefits. The broad applications for HIV protease and its inhibitors make it a perfect framework for integrating foundational topics in biochemistry around a big picture scientific and societal issue. Herein, I describe a series of classroom exercises that integrate foundational topics in biochemistry around the structure, biology, and therapeutic inhibition of HIV protease. These exercises center on foundational topics in biochemistry including thermodynamics, acid/base properties, protein structure, ligand binding, and enzymatic catalysis. The exercises also incorporate regular student practice of scientific skills including analysis of primary literature, evaluation of scientific data, and presentation of technical scientific arguments. Through the exercises, students also gain experience accessing computational biochemical resources such as the protein data bank, Proteopedia, and protein visualization software. As these HIV centered exercises cover foundational topics common to all first semester biochemistry courses, these exercises should appeal to a broad audience of undergraduate students and should be readily integrated into a variety of teaching styles and classroom sizes. © 2014 The International Union of Biochemistry and Molecular Biology.

A semester-long project-oriented biochemistry laboratory based on Helicobacter pylori urease.

PubMed

Farnham, Kate R; Dube, Danielle H

2015-01-01

Here we present the development of a 13 week project-oriented biochemistry laboratory designed to introduce students to foundational biochemical techniques and then enable students to perform original research projects once they have mastered these techniques. In particular, we describe a semester-long laboratory that focuses on a biomedically relevant enzyme--Helicobacter pylori (Hp) urease--the activity of which is absolutely required for the gastric pathogen Hp to colonize the human stomach. Over the course of the semester, students undertake a biochemical purification of Hp urease, assess the success of their purification, and investigate the activity of their purified enzyme. In the final weeks of the semester, students design and implement their own experiments to study Hp urease. This laboratory provides students with an understanding of the importance of biochemistry in human health while empowering them to engage in an active area of research. © 2015 The International Union of Biochemistry and Molecular Biology.

Trends in electro-optical electronic warfare

NASA Astrophysics Data System (ADS)

Smith, Carl R.; Grasso, Robert; Pledger, Jack; Murarka, Naveen

2012-09-01

Protection of military aircraft from hostile threats is paramount to ensure the survivability of aircrews, platforms, and mission success. While the threat environment continues to become more complex, shrinking defense budgets places new challenges on the development of electronic warfare (EW) systems. This paper presents the trends in electro-optical EW system development including 1) features, 2) affordability, 3) open architecture, 4) multi-functionality, 5) integrated avionics survivability equipment, and 6) enabling technologies for sensors, and optical sources. While these system attributes are not new, they have grown in importance in the design of EW systems. And, if treated correctly can have a beneficial symbiotic relationship to each other and to the airframe they support.

Biochemistry in Undergraduate Health Courses: Structure and Organization

ERIC Educational Resources Information Center

Silva, Irani F.; Batista, Nildo A.

2003-01-01

This article describes the following aspects of teaching biochemistry in undergraduate health courses: objectives, number of hours, time in which the subject is studied, selection of content, teaching strategies, and evaluation methodologies used. Fifty-three courses distributed in 13 areas within the health field and offered by 12 institutions…

Ultrasensitive detection of explosives and chemical warfare agents by low-pressure photoionization mass spectrometry.

PubMed

Sun, Wanqi; Liang, Miao; Li, Zhen; Shu, Jinian; Yang, Bo; Xu, Ce; Zou, Yao

2016-08-15

On-spot monitoring of threat agents needs high sensitive instrument. In this study, a low-pressure photoionization mass spectrometer (LPPI-MS) was employed to detect trace amounts of vapor-phase explosives and chemical warfare agent mimetics under ambient conditions. Under 10-s detection time, the limits of detection of 2,4-dinitrotoluene, nitrotoluene, nitrobenzene, and dimethyl methyl phosphonate were 30, 0.5, 4, and 1 parts per trillion by volume, respectively. As compared to those obtained previously with PI mass spectrometric techniques, an improvement of 3-4 orders of magnitude was achieved. This study indicates that LPPI-MS will open new opportunities for the sensitive detection of explosives and chemical warfare agents. Copyright © 2016 Elsevier B.V. All rights reserved.

Metal-organic frameworks for the removal of toxic industrial chemicals and chemical warfare agents.

PubMed

Bobbitt, N Scott; Mendonca, Matthew L; Howarth, Ashlee J; Islamoglu, Timur; Hupp, Joseph T; Farha, Omar K; Snurr, Randall Q

2017-06-06

Owing to the vast diversity of linkers, nodes, and topologies, metal-organic frameworks can be tailored for specific tasks, such as chemical separations or catalysis. Accordingly, these materials have attracted significant interest for capture and/or detoxification of toxic industrial chemicals and chemical warfare agents. In this paper, we review recent experimental and computational work pertaining to the capture of several industrially-relevant toxic chemicals, including NH 3 , SO 2 , NO 2 , H 2 S, and some volatile organic compounds, with particular emphasis on the challenging issue of designing materials that selectively adsorb these chemicals in the presence of water. We also examine recent research on the capture and catalytic degradation of chemical warfare agents such as sarin and sulfur mustard using metal-organic frameworks.

Drone warfare

NASA Astrophysics Data System (ADS)

Gusterson, Hugh

2017-11-01

Crude drones existed as early as World War I, but the technology matured in the Yugoslav Wars of the 1990s and the current wars around the Middle East. The U.S. first used a weaponized drone in late 2001, in Afghanistan. Drones may cause more or less civilian casualties depending on the targeting protocols employed by their operators. There is an inherent ambiguity in determining who is an insurgent from several thousand feet, but civilian casualties are likely to be higher if targeters emphasize "signature strikes" over "personality strikes," if they engage in "double-tap strikes," if they rely too much on local informants, and if they rely too heavily on cellphone identification in the absence of corroboration from other intelligence sources. The legality of drone warfare is fairly clear in established battle zones such as Afghanistan, but is more problematic in terms of both international and domestic law when it comes to drone strikes in countries such as Yemen, Pakistan and Somalia with which the U.S. is not at war. Looking to the future, the U.S. would be well advised to sponsor negotiations for an international drone convention that might establish clear international rules for the use of drones, ban autonomous smart drones, and establish adjudicatory procedures to handle allegations of war crimes.

Myoglobin structure and function: A multiweek biochemistry laboratory project.

PubMed

Silverstein, Todd P; Kirk, Sarah R; Meyer, Scott C; Holman, Karen L McFarlane

2015-01-01

We have developed a multiweek laboratory project in which students isolate myoglobin and characterize its structure, function, and redox state. The important laboratory techniques covered in this project include size-exclusion chromatography, electrophoresis, spectrophotometric titration, and FTIR spectroscopy. Regarding protein structure, students work with computer modeling and visualization of myoglobin and its homologues, after which they spectroscopically characterize its thermal denaturation. Students also study protein function (ligand binding equilibrium) and are instructed on topics in data analysis (calibration curves, nonlinear vs. linear regression). This upper division biochemistry laboratory project is a challenging and rewarding one that not only exposes students to a wide variety of important biochemical laboratory techniques but also ties those techniques together to work with a single readily available and easily characterized protein, myoglobin. © 2015 International Union of Biochemistry and Molecular Biology.

Probing Changes in the Conformation of tRNA[superscript Phe]: An Integrated Biochemistry Laboratory Course

ERIC Educational Resources Information Center

Kirk, Sarah R.; Silverstein, Todd P.; McFarlane Holman, Karen L.; Taylor, Buck L. H.

2008-01-01

We have designed a new guided-inquiry laboratory for an advanced biochemistry course. This integrated laboratory focuses on the biomolecule tRNA[superscript Phe] and combines elements of bioorganic and bioinorganic chemistry with biochemistry. Throughout the semester students work together to study tRNA[superscript Phe] structure and ligand…

Undergraduate Performance in Solving Ill-Defined Biochemistry Problems

ERIC Educational Resources Information Center

Sensibaugh, Cheryl A.; Madrid, Nathaniel J.; Choi, Hye-Jeong; Anderson, William L.; Osgood, Marcy P.

2017-01-01

With growing interest in promoting skills related to the scientific process, we studied performance in solving ill-defined problems demonstrated by graduating biochemistry majors at a public, minority-serving university. As adoption of techniques for facilitating the attainment of higher-order learning objectives broadens, so too does the need to…

Iron-montmorillonite clays as active sorbents for the decontamination of hazardous chemical warfare agents.

PubMed

Carniato, F; Bisio, C; Evangelisti, C; Psaro, R; Dal Santo, V; Costenaro, D; Marchese, L; Guidotti, M

2018-02-27

A class of heterogeneous catalysts based on commercial bentonite from natural origin, containing at least 80 wt% of montmorillonite clay, was designed to transform selectively and under mild conditions toxic organosulfur and organophosphorus chemical warfare agents into non-noxious products with a reduced impact on health and environment. The bentonite from the natural origin was modified by introducing iron species and acid sites in the interlayer space, aiming to obtain a sorbent with strong catalytic oxidising and hydrolytic properties. The catalytic performance of these materials was evaluated in the oxidative abatement of (2-chloroethyl)ethyl sulfide (CEES), a simulant of sulfur mustard, in the presence of aqueous hydrogen peroxide as an oxidant. A new decontamination formulation was, moreover, proposed and obtained by mixing sodium perborate, as a solid oxidant, to iron-bentonite catalysts. Solid-phase decontamination tests, performed on a cotton textile support contaminated with organosulfide and organophosphonate simulant agents revealed the good activity of the solid formulation, especially in the in situ detoxification of blistering agents. Tests carried out on the real blistering warfare agent, sulfur mustard (HD agent), showed that, thanks to the co-presence of the iron-based clay together with the solid oxidant component, a good decontamination of the test surface from the real warfare agent could be achieved (80% contaminant degradation, under ambient conditions, in 24 h).

A review of multi-threat medical countermeasures against chemical warfare and terrorism.

PubMed

Cowan, Fred M; Broomfield, Clarence A; Stojiljkovic, Milos P; Smith, William J

2004-11-01

The Multi-Threat Medical Countermeasure (MTMC) hypothesis has been proposed with the aim of developing a single countermeasure drug with efficacy against different pathologies caused by multiple classes of chemical warfare agents. Although sites and mechanisms of action and the pathologies caused by different chemical insults vary, common biochemical signaling pathways, molecular mediators, and cellular processes provide targets for MTMC drugs. This article will review the MTMC hypothesis for blister and nerve agents and will expand the scope of the concept to include other chemicals as well as briefly consider biological agents. The article will also consider how common biochemical signaling pathways, molecular mediators, and cellular processes that contribute to clinical pathologies and syndromes may relate to the toxicity of threat agents. Discovery of MTMC provides the opportunity for the integration of diverse researchers and clinicians, and for the exploitation of cutting-edge technologies and drug discovery. The broad-spectrum nature of MTMC can augment military and civil defense to combat chemical warfare and chemical terrorism.

Experimental examination of ultraviolet Raman cross sections of chemical warfare agent simulants

NASA Astrophysics Data System (ADS)

Kullander, F.; Landström, L.; Lundén, H.; Wästerby, Pär.

2015-05-01

Laser induced Raman scattering from the commonly used chemical warfare agent simulants dimethyl sulfoxide, tributyl phosphate, triethyl phosphonoacetate was measured at excitation wavelengths ranging from 210 to 410 nm using a pulsed laser based spectrometer system with a probing distance of 1.4 m and with a field of view on the target of less than 1mm. For the purpose of comparison with well explored reference liquids the Raman scattering from simulants was measured in the form of an extended liquid surface layer on top of a silicon wafer. This way of measuring enabled direct comparison to the Raman scattering strength from cyclohexane. The reference Raman spectra were used to validate the signal strength of the simulants and the calibration of the experimental set up. Measured UV absorbance functions were used to calculate Raman cross sections. Established Raman cross sections of the simulants make it possible to use them as reference samples when measuring on chemical warfare agents in droplet form.

Learning Effectiveness and Satisfaction of International Medical Students: Introducing a Hybrid-PBL Curriculum in Biochemistry

ERIC Educational Resources Information Center

Yan, Qiu; Ma, Li; Zhu, Lina; Zhang, Wenli

2017-01-01

A biochemistry course is a fundamental but important subject in medical education in China. In recent years, the number of international medical students has increased. Curriculum reform in biochemistry teaching is needed because of the knowledge limitations of students, a close linkage of biochemical content with clinics, the shortcomings of…

Multifunctional ultra-high vacuum apparatus for studies of the interactions of chemical warfare agents on complex surfaces

NASA Astrophysics Data System (ADS)

Wilmsmeyer, Amanda R.; Gordon, Wesley O.; Davis, Erin Durke; Mantooth, Brent A.; Lalain, Teri A.; Morris, John R.

2014-01-01

A fundamental understanding of the surface chemistry of chemical warfare agents is needed to fully predict the interaction of these toxic molecules with militarily relevant materials, catalysts, and environmental surfaces. For example, rules for predicting the surface chemistry of agents can be applied to the creation of next generation decontaminants, reactive coatings, and protective materials for the warfighter. Here, we describe a multifunctional ultra-high vacuum instrument for conducting comprehensive studies of the adsorption, desorption, and surface chemistry of chemical warfare agents on model and militarily relevant surfaces. The system applies reflection-absorption infrared spectroscopy, x-ray photoelectron spectroscopy, and mass spectrometry to study adsorption and surface reactions of chemical warfare agents. Several novel components have been developed to address the unique safety and sample exposure challenges that accompany the research of these toxic, often very low vapor pressure, compounds. While results of vacuum-based surface science techniques may not necessarily translate directly to environmental processes, learning about the fundamental chemistry will begin to inform scientists about the critical aspects that impact real-world applications.

Multifunctional ultra-high vacuum apparatus for studies of the interactions of chemical warfare agents on complex surfaces.

PubMed

Wilmsmeyer, Amanda R; Gordon, Wesley O; Davis, Erin Durke; Mantooth, Brent A; Lalain, Teri A; Morris, John R

2014-01-01

A fundamental understanding of the surface chemistry of chemical warfare agents is needed to fully predict the interaction of these toxic molecules with militarily relevant materials, catalysts, and environmental surfaces. For example, rules for predicting the surface chemistry of agents can be applied to the creation of next generation decontaminants, reactive coatings, and protective materials for the warfighter. Here, we describe a multifunctional ultra-high vacuum instrument for conducting comprehensive studies of the adsorption, desorption, and surface chemistry of chemical warfare agents on model and militarily relevant surfaces. The system applies reflection-absorption infrared spectroscopy, x-ray photoelectron spectroscopy, and mass spectrometry to study adsorption and surface reactions of chemical warfare agents. Several novel components have been developed to address the unique safety and sample exposure challenges that accompany the research of these toxic, often very low vapor pressure, compounds. While results of vacuum-based surface science techniques may not necessarily translate directly to environmental processes, learning about the fundamental chemistry will begin to inform scientists about the critical aspects that impact real-world applications.

Multifunctional ultra-high vacuum apparatus for studies of the interactions of chemical warfare agents on complex surfaces

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilmsmeyer, Amanda R.; Morris, John R.; Gordon, Wesley O.

2014-01-15

A fundamental understanding of the surface chemistry of chemical warfare agents is needed to fully predict the interaction of these toxic molecules with militarily relevant materials, catalysts, and environmental surfaces. For example, rules for predicting the surface chemistry of agents can be applied to the creation of next generation decontaminants, reactive coatings, and protective materials for the warfighter. Here, we describe a multifunctional ultra-high vacuum instrument for conducting comprehensive studies of the adsorption, desorption, and surface chemistry of chemical warfare agents on model and militarily relevant surfaces. The system applies reflection-absorption infrared spectroscopy, x-ray photoelectron spectroscopy, and mass spectrometry tomore » study adsorption and surface reactions of chemical warfare agents. Several novel components have been developed to address the unique safety and sample exposure challenges that accompany the research of these toxic, often very low vapor pressure, compounds. While results of vacuum-based surface science techniques may not necessarily translate directly to environmental processes, learning about the fundamental chemistry will begin to inform scientists about the critical aspects that impact real-world applications.« less

Operational Ethics: Just War and Implications for Contemporary American Warfare

DTIC Science & Technology

2003-05-22

will mutually share those values.12 Today, those values are manifested in the secular society in the form of ethics and basic human morality, what is...Approved for Public Release; Distribution is Unlimited Operational Ethics : Just War and Implications for Contemporary American Warfare A Monograph...a denkschrift through which the author hopes to inspire discussions on operational ethics among professional officers and civilian proponents of

Evaluation of Organisational Interoperabiity in a Network Centric Warfare Environment

DTIC Science & Technology

2004-09-01

understanding developed. Command and Coordination examines issues related to command structure, command and leadership styles . Ethos covers socio...harmonisation of command arrangements and the accommodation of differences in command and leadership styles . 3.2.4 Ethos Future warfare will... leadership styles . • changes to give less emphasis to hierarchy and command and more to coordination. Any reference to a single chain of command has been

Constitution aims to bring an end to health economy warfare.

PubMed

Harding, Mary-Louise; Martin, Daniel

2005-02-10

A rough new constitution is being drawn up for the NHS in a bid to prevent health economies sliding into bitter 'Bradford-style' warfare in the era of foundations trusts and payment by results. The rules of engagement are part of a package of measures designed to rescue some of the government's flagship reforms amid warnings from audit chiefs on the impact of PbR.

Marine Biochemistry: A New Interdisciplinary Course for the Interim

ERIC Educational Resources Information Center

Goldberg, Arthur S.

1976-01-01

Discusses an undergraduate course which includes lectures, laboratory, and field trips and is designed for the interim winter semester. The course is interdisciplinary, involving a study of the biochemistry, pharmacology, and physiological significance of compounds from marine flora and fauna. (MLH)

Application of Solid Phase Microextraction Coupled with Gas Chromatography/Mass Spectrometry as a Rapid Method for Field Sampling and Analysis of Chemical Warfare Agents and Toxic Industrial Chemicals

DTIC Science & Technology

2003-01-01

PHASE MICROEXTRACTION COUPLED WITH GAS CHROMATOGRAPHY/MASS SPECTROMETRY AS A RAPID METHOD FOR FIELD SAMPLING AND ANALYSIS OF CHEMICAL WARFARE AGENTS...SAMPLING AND ANALYSIS OF CHEMICAL WARFARE AGENTS AND TOXIC INDUSTRIAL CHEMICALS 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...GAS CHROMATOGRAPHY/MASS SPECTROMETRY AS A RAPID METHOD FOR FIELD SAMPLING AND ANALYSIS OF CHEMICAL WARFARE AGENTS AND TOXIC INDUSTRIAL CHEMICALS

North Korean Protective Mine Warfare: An Analysis of the Naval Minefields at Wonsan, Chinnampo and Hungnam during the Korean War

DTIC Science & Technology

2010-04-01

the United States Navy and the general military history community as well. As a result, studies involving mine warfare have been neglected. In...that particular campaign. The Navy, lulled into a sense of complacency, has neglected mine warfare studies . Naval Intelligence has made little attempt...Farragut famously ignored the mineline there to destroy the Confederate fleet nearby. While extensive mining also occurred during World War One , the United

PERMANENCE OF BIOLOGICAL AND CHEMICAL WARFARE AGENTS IN MUNICIPAL SOLID WASTE LANDFILL LEACHATES

EPA Science Inventory

The objective of this work is to permit EPA/ORD's National Homeland Security Research Center (NHSRC) and Edgewood Chemical Biological Center to collaborate together to test the permanence of biological and chemical warfare agents in municipal solid waste landfills. Research into ...

Raising Environmental Awareness through Applied Biochemistry Laboratory Experiments

ERIC Educational Resources Information Center

Salman Ashraf, S.

2013-01-01

Our environment is under constant pressure and threat from various sources of pollution. Science students, in particular chemistry students, must not only be made aware of these issues, but also be taught that chemistry (and science) can provide solutions to such real-life issues. To this end, a newly developed biochemistry laboratory experiment…

Intraosseous vascular access in the treatment of chemical warfare casualties assessed by advanced simulation: proposed alteration of treatment protocol.

PubMed

Vardi, Amir; Berkenstadt, Haim; Levin, Inbal; Bentencur, Ariel; Ziv, Amitai

2004-06-01

Current treatment protocols for chemical warfare casualties assume no IV access during the early treatment stages. Time constraints in mass casualty scenarios, impaired manual dexterity of medical personnel wearing protective gear, and victims' complex clinical presentations render standard IV access techniques impractical. A newly developed spring-driven, trigger-operated intraosseous infusion device may offer an effective solution. Sophisticated simulators were developed and used to mimic scenarios of chemical warfare casualties for assessing the feasibility of intraosseous infusion delivery. We evaluated the clinical performance of medical teams in full protective gear. The success rate in intraosseous insertion, time to completion of treatment goals, and outcome were measured in a simulated setting. Medical teams from major hospitals in Israel, designated for emergency response in a real chemical warfare mass casualty scenario, were trained in a simulated setting. All 94 participating physicians were supplied with conventional treatment modalities: only the 64 study group physicians received intraosseous devices. The simulated survival rate was 73.4% for the study group and 3.3% for the controls (P < 0.001). Treatment goals were achieved within 3.5 min (range, 1-9 min) in the study group and within >10 min for controls (P < 0.001), and the complication rate for intraosseous use was 13.8%. Personnel satisfaction with the intraosseous device was unanimous and high. New-generation intraosseous infusions have great potential value in the early treatment stages of chemical warfare casualties. In a chemical warfare mass casualty scenario, the protective gear worn by medical personnel, the time constraints, and the casualties' medical condition impose limitations on the establishment of IV access during early treatment of the victims. A spring-driven, trigger-operated intraosseous infusion delivery system may offer an effective solution.

Chemical-warfare techniques for insect control: insect 'pests' in Germany before and after World War I.

PubMed

Jansen, S

2000-01-01

During World War I, chemical-warfare practices were introduced into economic entomology in Germany. Fritz Haber, 'the father of chemical warfare', realized that Germany could not win the war and thus looked for 'civilian' uses for his chemical arsenal. Before the war, there was a rhetoric of dangerous 'masses' of insects but the large-scale techniques needed to deal with them had not been developed. The gap between rhetoric and practices enabled entomology to integrate chemical weapons into its working methods. This article traces transformations in the ways of seeing insects and their control from the mid-nineteenth century to after World War I.

Getting the Next War Right: Beyond Population-centric Warfare

DTIC Science & Technology

2010-06-01

respectively: Che Guevara and Mao Tse -tung. Che’s foco theory, as we have discussed, advocates mobilizing from the top. The armed challenger chooses an...example, Thomas A. Marks, “Guerrillas in the Mist: Hmong Resistance Continues in Laos ,” Combat and Survival 8, no. 5 (August 1996), 4–11. 12 Theory and...Mao Tse -tung, On Guerrilla Warfare, trans. and ed. Samuel B. Grif!th (Mineola, NY: Dover Publications, 2005). The book is available from a wide

Characterizing and Exploring the Implications of Maritime Irregular Warfare

DTIC Science & Technology

2012-01-01

1 The study’s dependent variable was conflict processes and outcomes in maritime warfare environments, and the independent variable was IW...capabilities are improving, or it may mean that the fre- quency of SPSS voyages is increasing, which would bode poorly for U.S. efforts to halt these shipments...Red Sea in the west to 76 degrees longitude in the east, 22 degrees in the south, and 21.5 degrees in the north (Bandel and Crowley, 2008; GAO, 2010

The Effect of Shipboard Design Decisions in Amphibious Warfare

DTIC Science & Technology

2012-06-01

appreciate all that you have done for me over the past 18 months. Lastly, I would like to thank The Bosn for teaching me all about amphibs and...amphibious warfare field of expertise were also conducted to gain firsthand knowledge and gather data. Once all of the data were collected, a comparative...the U.S. entered World War II, Japan was able to extend their empire across the entire Pacific Ocean relatively unopposed, which in all probably led

Reevaluation of 1999 Health-Based Environmental Screening Levels (HBESLs) for Chemical Warfare Agents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watson, Annetta Paule; Dolislager, Fredrick G

2007-05-01

This report evaluates whether new information and updated scientific models require that changes be made to previously published health-based environmental soil screening levels (HBESLs) and associated environmental fate/breakdown information for chemical warfare agents (USACHPPM 1999). Specifically, the present evaluation describes and compares changes that have been made since 1999 to U.S. Environmental Protection Agency (EPA) risk assessment models, EPA exposure assumptions, as well as to specific chemical warfare agent parameters (e.g., toxicity values). Comparison was made between screening value estimates recalculated with current assumptions and earlier health-based environmental screening levels presented in 1999. The chemical warfare agents evaluated include themore » G-series and VX nerve agents and the vesicants sulfur mustard (agent HD) and Lewisite (agent L). In addition, key degradation products of these agents were also evaluated. Study findings indicate that the combined effect of updates and/or changes to EPA risk models, EPA default exposure parameters, and certain chemical warfare agent toxicity criteria does not result in significant alteration to the USACHPPM (1999) health-based environmental screening level estimates for the G-series and VX nerve agents or the vesicant agents HD and L. Given that EPA's final position on separate Tier 1 screening levels for indoor and outdoor worker screening assessments has not yet been released as of May 2007, the study authors find that the 1999 screening level estimates (see Table ES.1) are still appropriate and protective for screening residential as well as nonresidential sites. As such, risk management decisions made on the basis of USACHPPM (1999) recommendations do not require reconsideration. While the 1999 HBESL values are appropriate for continued use as general screening criteria, the updated '2007' estimates (presented below) that follow the new EPA protocols currently under development are also

Protein Science by DNA Sequencing: How Advances in Molecular Biology Are Accelerating Biochemistry.

PubMed

Higgins, Sean A; Savage, David F

2018-01-09

A fundamental goal of protein biochemistry is to determine the sequence-function relationship, but the vastness of sequence space makes comprehensive evaluation of this landscape difficult. However, advances in DNA synthesis and sequencing now allow researchers to assess the functional impact of every single mutation in many proteins, but challenges remain in library construction and the development of general assays applicable to a diverse range of protein functions. This Perspective briefly outlines the technical innovations in DNA manipulation that allow massively parallel protein biochemistry and then summarizes the methods currently available for library construction and the functional assays of protein variants. Areas in need of future innovation are highlighted with a particular focus on assay development and the use of computational analysis with machine learning to effectively traverse the sequence-function landscape. Finally, applications in the fundamentals of protein biochemistry, disease prediction, and protein engineering are presented.

Synthesis of Vitamin K Expoxide: An Undergraduate Biochemistry Experiment.

ERIC Educational Resources Information Center

Thierry-Palmer, M.

1984-01-01

Provides procedures for synthesizing and purifying a vitamin K metabolite (2,3-epoxide) to introduce many of the techniques used in lipid biochemistry. Includes typical results obtained as well as an optional experiment designed to test the purity of the epoxide obtained. (JM)

Biochemistry Instructors' Perceptions of Analogies and Their Classroom Use

ERIC Educational Resources Information Center

Orgill, MaryKay; Bussey, Thomas J.; Bodner, George M.

2015-01-01

Biochemistry education relies heavily on students' abilities to conceptualize abstract cellular and molecular processes, mechanisms, and components. From a constructivist standpoint, students build their understandings of these abstract processes by connecting, expanding, or revising their prior conceptions and experiences. As such, biochemistry…

Summary report of a workshop on research opportunities in plant biochemistry, December 11--13, 1992, Kona, Hawaii

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-12-31

A DOE-sponsored workshop was held December 11--13, 1992 in Kona, Hawaii to discuss those aspects of fundamental research in plant biochemistry deemed essential to provide the basic information base necessary for exploiting plant biotechnology to meet future societal needs. Twenty nine scientists, with interests representing many of the various areas of plant biochemistry, participated. The workshop was intended to define in both broad and specific terms the current state of knowledge in the general area of metabolic biochemistry, and to identify those areas that afford unusual opportunity or that are relatively underdeveloped in comparison with other areas of plant biology.more » Participants provided critiques of the state of knowledge of the major areas of metabolic biochemistry in relation to a series of questions that are presented herein.« less

MRAPs, Irregular Warfare, and Pentagon Reform

DTIC Science & Technology

2009-01-01

76 JFQ / issue 55, 4 th quarter 2009 ndupress .ndu.edu MRAPs, Irregular Warfare, and Pentagon Reform By C h r i s t o p h e r J . l a m b , m...a t t h e w J . s C h m i D t , and b e r i t g . F i t z s i m m o n s Mine resistant ambush protected (MRAP) vehicles offer an excellent...issue 55, 4 th quarter 2009 / JFQ 77 LAMB, SCHMIDT, and FITZSIMMONS By C h r i s t o p h e r J . l a m b , m a t t h e w J . s C h m i D t

Design of a comprehensive biochemistry and molecular biology experiment: phase variation caused by recombinational regulation of bacterial gene expression.

PubMed

Sheng, Xiumei; Xu, Shungao; Lu, Renyun; Isaac, Dadzie; Zhang, Xueyi; Zhang, Haifang; Wang, Huifang; Qiao, Zheng; Huang, Xinxiang

2014-01-01

Scientific experiments are indispensable parts of Biochemistry and Molecular Biology. In this study, a comprehensive Biochemistry and Molecular Biology experiment about Salmonella enterica serovar Typhi Flagellar phase variation has been designed. It consisted of three parts, namely, inducement of bacterial Flagellar phase variation, antibody agglutination test, and PCR analysis. Phase variation was observed by baterial motility assay and identified by antibody agglutination test and PCR analysis. This comprehensive experiment can be performed to help students improve their ability to use the knowledge acquired in Biochemistry and Molecular Biology. Copyright © 2014 by The International Union of Biochemistry and Molecular Biology.

Chymotrypsin effects on the determination of sperm parameters and seminal biochemistry markers.

PubMed

Chen, Fang; Lu, Jin-Chun; Xu, Hui-Ru; Huang, Yu-Feng; Lu, Nian-Qing

2006-01-01

Few reports of the effects of treatment with chymotrypsin on the determination of sperm parameters and seminal biochemistry markers are documented. Sperm parameters of 63 liquefied and 27 non-liquefied samples, untreated or treated with chymotrypsin, were evaluated using computer-assisted semen analysis. In addition, biochemistry markers such as gamma-glutamyltranspeptidase, alpha-glucosidase and fructose in 50 liquefied and 39 non-liquefied samples, untreated or treated with chymotrypsin, were determined. Treatment with chymotrypsin had no effect on sperm concentration, motility, motility a and b, straightness, curvilinear velocity, straight line velocity, average path velocity and beat cross frequency in both liquefied and non-liquefied semen. However, linearity (p=0.025) decreased and the amplitude of the lateral head (p=0.029) increased significantly in non-liquefied semen after treatment with chymotrypsin. The levels of gamma-glutamyltranspeptidase, alpha-glucosidase and fructose in seminal plasma were unaffected by chymotrypsin, regardless of liquefaction status. Chymotrypsin had no effects on the detection of sperm parameters and biochemistry markers, and could be used to treat non-liquefied samples before semen analysis in the andrology laboratory.

Identification of the students' critical thinking skills through biochemistry laboratory work report

NASA Astrophysics Data System (ADS)

Anwar, Yunita Arian Sani; Senam, Laksono, Endang W.

2017-08-01

This work aims to (1) identify the critical thinking skills of student based on their ability to set up laboratory work reports, and (2) analyze the implementation of biochemistry laboratory work. The method of quantitative content analysis was employed. Quantitative data were in the form of critical thinking skills through the assessment of students' laboratory work reports and questionnaire data. Hoyo rubric was used to measure critical thinking skills with 10 indicators, namely clarity, accuracy, precision, consistency, relevance, evidence, reason, depth, breadth, and fairness. The research sample consisted of 105 students (35 male, 70 female) of Mataram University who took a Biochemistry course and 2 lecturers of Biochemistry course. The results showed students' critical thinking skills through laboratory work reports were still weak. Analysis of the questionnaire showed that three indicators become the biggest problems during the laboratory work implementation, namely, lecturers' involved in laboratory work implementation, the integration of laboratory work implementation of learning in the classroom has not been done optimally and laboratory work implementation as an effort to train critical thinking skills is not optimal yet.

Chemistry and Biochemistry of Dietary Polyphenols

PubMed Central

Tsao, Rong

2010-01-01

Polyphenols are the biggest group of phytochemicals, and many of them have been found in plant-based foods. Polyphenol-rich diets have been linked to many health benefits. This paper is intended to review the chemistry and biochemistry of polyphenols as related to classification, extraction, separation and analytical methods, their occurrence and biosynthesis in plants, and the biological activities and implications in human health. The discussions are focused on important and most recent advances in the above aspects, and challenges are identified for future research. PMID:22254006

Comparison of student confidence and perceptions of biochemistry concepts using a team-based learning versus traditional lecture-based format.

PubMed

Gryka, Rebecca; Kiersma, Mary E; Frame, Tracy R; Cailor, Stephanie M; Chen, Aleda M H

To evaluate differences in student confidence and perceptions of biochemistry concepts using a team-based learning (TBL) format versus a traditional lecture-based format at two universities. Two pedagogies (TBL vs lecture-based) were utilized to deliver biochemistry concepts at two universities in a first-professional year, semester-long biochemistry course. A 21-item instrument was created and administered pre-post semester to assess changes in confidence in learning biochemistry concepts using Bandura's Social Cognitive Theory (eight items, 5-point, Likert-type) and changes in student perceptions of biochemistry utilizing the theory of planned behavior (TPB) domains (13 items, 7- point, Likert-type). Wilcoxon signed-rank tests were used to evaluate pre-post changes, and Mann Whitney U tests for differences between universities. All students (N=111) had more confidence in biochemistry concepts post-semester, but TBL students (N=53) were significantly more confident. TBL students also had greater agreement that they are expected to actively engage in science courses post-semester, according to the perceptions of biochemistry subscale. No other differences between lecture and TBL were observed post-semester. Students in a TBL course had greater gains in confidence. Since students often engage in tasks where they feel confident, TBL can be a useful pedagogy to promote student learning. Copyright © 2017 Elsevier Inc. All rights reserved.

Textile/metal-organic-framework composites as self-detoxifying filters for chemical-warfare agents.

PubMed

López-Maya, Elena; Montoro, Carmen; Rodríguez-Albelo, L Marleny; Aznar Cervantes, Salvador D; Lozano-Pérez, A Abel; Cenís, José Luis; Barea, Elisa; Navarro, Jorge A R

2015-06-01

The current technology of air-filtration materials for protection against highly toxic chemicals, that is, chemical-warfare agents, is mainly based on the broad and effective adsorptive properties of hydrophobic activated carbons. However, adsorption does not prevent these materials from behaving as secondary emitters once they are contaminated. Thus, the development of efficient self-cleaning filters is of high interest. Herein, we report how we can take advantage of the improved phosphotriesterase catalytic activity of lithium alkoxide doped zirconium(IV) metal-organic framework (MOF) materials to develop advanced self-detoxifying adsorbents of chemical-warfare agents containing hydrolysable P-F, P-O, and C-Cl bonds. Moreover, we also show that it is possible to integrate these materials onto textiles, thereby combining air-permeation properties of the textiles with the self-detoxifying properties of the MOF material. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Organizing for Irregular Warfare: Implications for the Brigade Combat Team

DTIC Science & Technology

2007-12-01

suggestions to improve his beloved institution. xii THIS PAGE INTENTIONALLY LEFT BLANK 1 I. INTRODUCTION The Army ended up trying to fight...Secretary of Defense and supported by the Chairman of the Joint Chiefs of Staff, was improving Special Operations Forces (SOF) and general purpose...applicable to all three missions within the larger term of irregular warfare. This paper may interchange some terms due their associations from varying

American Military History and its Insights into Fourth Generation Warfare

DTIC Science & Technology

2006-01-01

8William S . Lind, Colonel Keith Nightengale (USA), Captain John F. Schmitt (USMC), Colonel Joseph W. Sutton (USA), and Lieutenant Colonel Gary I. Wilson...Lind, William S ., Colonel Keith Nightengale (USA), Captain John F. Schmitt (USMC), Colonel Joseph W. Sutton (USA), and Lieutenant Colonel Gary I...military history and its insights into fourth generation warfare. 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S

An Integrated Approach to Teaching Biochemistry for Pharmacy Students.

ERIC Educational Resources Information Center

Poirier, Therese I.; Borke, Mitchell L.

1982-01-01

A Duquesne course integrating biochemistry lectures, clinical applications lectures, and laboratory sessions has the objectives of (1) making the course more relevant to students' perceived needs; (2) enhancing the learning process; (3) introducing clinical applications early in the students' program; and (4) demonstrating additional…

An Appraisal of a New Undergraduate Biochemistry Research Project.

ERIC Educational Resources Information Center

Adamson, Ishola

1980-01-01

Described is the first part of a two-term project involving final-year students in biochemistry. Listed are the required experiments compiled to test students' abilities to search biochemical literature, extract experiments from journals and carry them out, generate data, and interpret results. (CS)

Teaching Structure: Student Use of Software Tools for Understanding Macromolecular Structure in an Undergraduate Biochemistry Course

ERIC Educational Resources Information Center

Jaswal, Sheila S.; O'Hara, Patricia B.; Williamson, Patrick L.; Springer, Amy L.

2013-01-01

Because understanding the structure of biological macromolecules is critical to understanding their function, students of biochemistry should become familiar not only with viewing, but also with generating and manipulating structural representations. We report a strategy from a one-semester undergraduate biochemistry course to integrate use of…

Differentiating Biochemistry Course Laboratories Based on Student Experience

ERIC Educational Resources Information Center

Jakubowski, Henry V.

2011-01-01

Content and emphases in undergraduate biochemistry courses can be readily tailored to accommodate the standards of the department in which they are housed, as well as the backgrounds of the students in the courses. A more challenging issue is how to construct laboratory experiences for a class with both chemistry majors, who usually have little or…

Isotopic inferences of ancient biochemistries - Carbon, sulfur, hydrogen, and nitrogen

NASA Technical Reports Server (NTRS)

Schidlowski, M.; Hayes, J. M.; Kaplan, I. R.

1983-01-01

In processes of biological incorporation and subsequent biochemical processing sizable isotope effects occur as a result of both thermodynamic and kinetic fractionations which take place during metabolic and biosynthetic reactions. In this chapter a review is provided of earlier work and recent studies on isotope fractionations in the biogeochemical cycles of carbon, sulfur, hydrogen, and nitrogen. Attention is given to the biochemistry of carbon isotope fractionation, carbon isotope fractionation in extant plants and microorganisms, isotope fractionation in the terrestrial carbon cycle, the effects of diagenesis and metamorphism on the isotopic composition of sedimentary carbon, the isotopic composition of sedimentary carbon through time, implications of the sedimentary carbon isotope record, the biochemistry of sulfur isotope fractionation, pathways of the biogeochemical cycle of nitrogen, and the D/H ratio in naturally occurring materials.

Modern Warfare: NATO’s War amongst the People in Kosovo

DTIC Science & Technology

2013-05-23

Defense Initiative and director of research for the Foreign Policy program at the Brookings Institution; Misha Glenny, then the Central... the Kosovo military campaign and offers useful incites regarding future 21st century warfare for those who are interested in advancing their...estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the

Asymmetric Warfare in the Simulation and Training Environment: Comprehensive Approach Wanted!

DTIC Science & Technology

2009-10-01

Covering Support to Operations, Human Behaviour Representation, Irregular Warfare, Defence against Terrorism and Coalition Tactical Force Integration...learned behaviours arising from shared knowledge and it is passed on from one generation to the next. The behaviours that have become embedded as part of...symbols and behaviours . While culture changes, the change is usually slow, particularly in terms of military operations timeframes. Urban environments

Fluorescent discrimination between traces of chemical warfare agents and their mimics.

PubMed

Díaz de Greñu, Borja; Moreno, Daniel; Torroba, Tomás; Berg, Alexander; Gunnars, Johan; Nilsson, Tobias; Nyman, Rasmus; Persson, Milton; Pettersson, Johannes; Eklind, Ida; Wästerby, Pär

2014-03-19

An array of fluorogenic probes is able to discriminate between nerve agents, sarin, soman, tabun, VX and their mimics, in water or organic solvent, by qualitative fluorescence patterns and quantitative multivariate analysis, thus making the system suitable for the in-the-field detection of traces of chemical warfare agents as well as to differentiate between the real nerve agents and other related compounds.

Integrating bio-inorganic and analytical chemistry into an undergraduate biochemistry laboratory.

PubMed

Erasmus, Daniel J; Brewer, Sharon E; Cinel, Bruno

2015-01-01

Undergraduate laboratories expose students to a wide variety of topics and techniques in a limited amount of time. This can be a challenge and lead to less exposure to concepts and activities in bio-inorganic chemistry and analytical chemistry that are closely-related to biochemistry. To address this, we incorporated a new iron determination by atomic absorption spectroscopy exercise as part of a five-week long laboratory-based project on the purification of myoglobin from beef. Students were required to prepare samples for chemical analysis, operate an atomic absorption spectrophotometer, critically evaluate their iron data, and integrate these data into a study of myoglobin. © 2015 The International Union of Biochemistry and Molecular Biology.

A Curriculum Skills Matrix for Development and Assessment of Undergraduate Biochemistry and Molecular Biology Laboratory Programs

ERIC Educational Resources Information Center

Caldwell, Benjamin; Rohlman, Christopher; Benore-Parsons, Marilee

2004-01-01

We have designed a skills matrix to be used for developing and assessing undergraduate biochemistry and molecular biology laboratory curricula. We prepared the skills matrix for the Project Kaleidoscope Summer Institute workshop in Snowbird, Utah (July 2001) to help current and developing undergraduate biochemistry and molecular biology program…

A Comparison of Neutron-Based Non-Destructive Assessment Methods for Chemical Warfare Materiel and High Explosives

DOE Office of Scientific and Technical Information (OSTI.GOV)

E.H. Seabury; D.L. Chichester; C.J. Wharton

2008-08-01

Prompt Gamma Neutron Activation Analysis (PGNAA) systems employ neutrons as a probe to interrogate items, e.g. chemical warfare materiel-filled munitions. The choice of a neutron source in field-portable systems is determined by its ability to excite nuclei of interest, operational concerns such as radiological safety and ease-of-use, and cost. Idaho National Laboratory’s PINS Chemical Assay System has traditionally used a Cf-252 isotopic neutron source, but recently a Deuterium-Tritium (DT) Electronic Neutron Generator (ENG) has been tested as an alternate neutron source. This paper presents the results of using both of these neutron sources to interrogate chemical warfare materiel (CWM) andmore » high explosive (HE) filled munitions.« less

A Comparison of Neutron-Based Non-Destructive Assessment Methods for Chemical Warfare Material and High Explosives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seabury, E. H.; Chichester, D. L.; Wharton, C. J.

2009-03-10

Prompt Gamma Neutron Activation Analysis (PGNAA) systems employ neutrons as a probe to interrogate items, e.g. chemical warfare materiel-filled munitions. The choice of a neutron source in field-portable systems is determined by its ability to excite nuclei of interest, operational concerns such as radiological safety and ease-of-use, and cost. Idaho National Laboratory's PINS Chemical Assay System has traditionally used a {sup 252}Cf isotopic neutron source, but recently a deuterium-tritium (DT) electronic neutron generator (ENG) has been tested as an alternate neutron source. This paper presents the results of using both of these neutron sources to interrogate chemical warfare materiel (CWM)more » and high explosive (HE) filled munitions.« less

Brain Biochemistry and Personality: A Magnetic Resonance Spectroscopy Study

PubMed Central

Ryman, Sephira G.; Gasparovic, Chuck; Bedrick, Edward J.; Flores, Ranee A.; Marshall, Alison N.; Jung, Rex E.

2011-01-01

To investigate the biochemical correlates of normal personality we utilized proton magnetic resonance spectroscopy (1H-MRS). Our sample consisted of 60 subjects ranging in age from 18 to 32 (27 females). Personality was assessed with the NEO Five-Factor Inventory (NEO-FFI). We measured brain biochemistry within the precuneus, the cingulate cortex, and underlying white matter. We hypothesized that brain biochemistry within these regions would predict individual differences across major domains of personality functioning. Biochemical models were fit for all personality domains including Neuroticism, Extraversion, Openness, Agreeableness, and Conscientiousness. Our findings involved differing concentrations of Choline (Cho), Creatine (Cre), and N-acetylaspartate (NAA) in regions both within (i.e., posterior cingulate cortex) and white matter underlying (i.e., precuneus) the Default Mode Network (DMN). These results add to an emerging literature regarding personality neuroscience, and implicate biochemical integrity within the default mode network as constraining major personality domains within normal human subjects. PMID:22073190

Development of biosensors for the detection of biological warfare agents: its issues and challenges.

PubMed

Kumar, Harish; Rani, Renu

2013-01-01

This review discusses current development in biosensors for the detection of biological warfare agents (BWAs). BWAs include bacteria, virus and toxins that are added deliberately into air water and food to spread terrorism and cause disease or death. The rapid and unambiguous detection and identification of BWAs with early warning signals for detecting possible biological attack is a major challenge for government agencies particularly military and health. The detection devices--biosensors--can be classified (according to their physicochemical transducers) into four types: electrochemical, nucleic acid, optical and piezoelectric. Advantages and limitations of biosensors are discussed in this review followed by an assessment of the current state of development of different types of biosensors. The research and development in biosensors for biological warfare agent detection is of great interest for the public as well as for governments.

Comprehensive experiment-clinical biochemistry: determination of blood glucose and triglycerides in normal and diabetic rats.

PubMed

Jiao, Li; Xiujuan, Shi; Juan, Wang; Song, Jia; Lei, Xu; Guotong, Xu; Lixia, Lu

2015-01-01

For second year medical students, we redesigned an original laboratory experiment and developed a combined research-teaching clinical biochemistry experiment. Using an established diabetic rat model to detect blood glucose and triglycerides, the students participate in the entire experimental process, which is not normally experienced during a standard clinical biochemistry exercise. The students are not only exposed to techniques and equipment but are also inspired to think more about the biochemical mechanisms of diseases. When linked with lecture topics about the metabolism of carbohydrates and lipids, the students obtain a better understanding of the relevance of abnormal metabolism in relation to diseases. Such understanding provides a solid foundation for the medical students' future research and for other clinical applications. © 2014 Biochemistry and Molecular Biology Education.

A model for warfare in stratified small-scale societies: The effect of within-group inequality.

PubMed

Pandit, Sagar; Pradhan, Gauri; van Schaik, Carel

2017-01-01

In order to predict the features of non-raiding human warfare in small-scale, socially stratified societies, we study a coalitionary model of war that assumes that individuals participate voluntarily because their decisions serve to maximize fitness. Individual males join the coalition if war results in a net economic and thus fitness benefit. Within the model, viable offensive war ensues if the attacking coalition of males can overpower the defending coalition. We assume that the two groups will eventually fuse after a victory, with ranks arranged according to the fighting abilities of all males and that the new group will adopt the winning group's skew in fitness payoffs. We ask whether asymmetries in skew, group size and the amount of resources controlled by a group affect the likelihood of successful war. The model shows, other things being equal, that (i) egalitarian groups are more likely to defeat their more despotic enemies, even when these are stronger, (ii) defection to enemy groups will be rare, unless the attacked group is far more despotic than the attacking one, and (iii) genocidal war is likely under a variety of conditions, in particular when the group under attack is more egalitarian. This simple optimality model accords with several empirically observed correlations in human warfare. Its success underlines the important role of egalitarianism in warfare.

A model for warfare in stratified small-scale societies: The effect of within-group inequality

PubMed Central

Pandit, Sagar; van Schaik, Carel

2017-01-01

In order to predict the features of non-raiding human warfare in small-scale, socially stratified societies, we study a coalitionary model of war that assumes that individuals participate voluntarily because their decisions serve to maximize fitness. Individual males join the coalition if war results in a net economic and thus fitness benefit. Within the model, viable offensive war ensues if the attacking coalition of males can overpower the defending coalition. We assume that the two groups will eventually fuse after a victory, with ranks arranged according to the fighting abilities of all males and that the new group will adopt the winning group’s skew in fitness payoffs. We ask whether asymmetries in skew, group size and the amount of resources controlled by a group affect the likelihood of successful war. The model shows, other things being equal, that (i) egalitarian groups are more likely to defeat their more despotic enemies, even when these are stronger, (ii) defection to enemy groups will be rare, unless the attacked group is far more despotic than the attacking one, and (iii) genocidal war is likely under a variety of conditions, in particular when the group under attack is more egalitarian. This simple optimality model accords with several empirically observed correlations in human warfare. Its success underlines the important role of egalitarianism in warfare. PMID:29228014

Unconventional Warfare: A Mission Metamorphosis for the 21st Century?

DTIC Science & Technology

2000-06-01

technology, the trend for insurgent groups to use the internet to advance their cause or exploit propaganda is sure to increase. Insurgent groups using ...Zapatistas, they used “social net war” to put pressure on the Mexican government. Efforts such as this are expected to continue and are extremely important...authority of the local government or occupying power, and using primarily irregular and informal groupings and measures.246 FM 31-21 Guerrilla Warfare

Bio Warfare and Terrorism: Toxins and Other Mid-Spectrum Agents

DTIC Science & Technology

2005-01-01

biotechnology, toxicogenomics, toxin, tetrodotoxin, and others. Once an agent has and proteomics may also help to open the door to the 276 Bio Warfare...also interferon gamma, interleukin-6, and tumor alsointrfern gmma intrlekin6, ad tmor by the mold Aspergillus flavus and commonly conta- necrosis factor...as bullets. No the new sciences of genomics and proteomics to alter toxoid or antitoxin is available, genetic code and to affect the expression of

The Entomological Institute of the Waffen-SS: evidence for offensive biological warfare research in the third Reich.

PubMed

Reinhardt, Klaus

2013-12-01

In January 1942, Heinrich Himmler, head of the Schutzstaffel (SS) and police in Nazi Germany, ordered the creation of an entomological institute to study the physiology and control of insects that inflict harm to humans. Founded in the grounds of the concentration camp at Dachau, it has been the focus of previous research, notably into the question of whether it was involved in biological warfare research. This article examines research protocols by the appointed leader Eduard May, presented here for the first time, which confirm the existence of an offensive biological warfare research programme in Nazi Germany. Copyright © 2013 Elsevier Ltd. All rights reserved.

Technology Transfer Summary Report (FY92), Naval Surface Warfare Center Dahlgren Division

DTIC Science & Technology

1994-04-20

communications; no formal records are kept of these. Community Technical Outreach NSWCDD participates in the "Science and Engineering Apprentice" and the " Bay ...ADMINISTRATOR’S OFFICE NAVAL UNDERSEA WARFARE CENTER PO BOX 545 DIVISION NEWPORT SEQUIM WA 98382 NEWPORI’ RI 02841-5047 ATTN GIFT AND EXCHANGE DIV 4 ATTN CODE 00

Assessment of Learning Gains in a Flipped Biochemistry Classroom

ERIC Educational Resources Information Center

Ojennus, Deanna Dahlke

2016-01-01

The flipped classroom has become an increasingly popular pedagogical approach to teaching and learning. In this study, learning gains were assessed in a flipped biochemistry course and compared to gains in a traditional lecture. Although measured learning gains were not significantly different between the two courses, student perception of…

Using Assessment to Improve Learning in the Biochemistry Classroom

ERIC Educational Resources Information Center

Loertscher, Jennifer

2010-01-01

In recent years, major drivers of undergraduate science education reform including the National Science Foundation (NSF) and the Howard Hughes Medical Institute (HHMI) have called on college and university instructors to take a more scientific approach to their teaching. Although many biochemistry instructors are gaining confidence in using…

Ultraviolet Raman scattering from persistent chemical warfare agents

NASA Astrophysics Data System (ADS)

Kullander, Fredrik; Wästerby, Pär.; Landström, Lars

2016-05-01

Laser induced Raman scattering at excitation wavelengths in the middle ultraviolet was examined using a pulsed tunable laser based spectrometer system. Droplets of chemical warfare agents, with a volume of 2 μl, were placed on a silicon surface and irradiated with sequences of laser pulses. The Raman scattering from V-series nerve agents, Tabun (GA) and Mustard gas (HD) was studied with the aim of finding the optimum parameters and the requirements for a detection system. A particular emphasis was put on V-agents that have been previously shown to yield relatively weak Raman scattering in this excitation band.

Drug Synthesis and Analysis on a Dime: A Capstone Medicinal Chemistry Experience for the Undergraduate Biochemistry Laboratory

ERIC Educational Resources Information Center

Streu, Craig N.; Reif, Randall D.; Neiles, Kelly Y.; Schech, Amanda J.; Mertz, Pamela S.

2016-01-01

Integrative, research-based experiences have shown tremendous potential as effective pedagogical approaches. Pharmaceutical development is an exciting field that draws heavily on organic chemistry and biochemistry techniques. A capstone drug synthesis/analysis laboratory is described where biochemistry students synthesize azo-stilbenoid compounds…

Personalized System of Instruction (Keller Method) for Medical School Biochemistry

ERIC Educational Resources Information Center

Weisman, Robert A.; Shapiro, David M.

1973-01-01

The Keller Method requires abolishing lectures as a vehicle of information transfer in favor of a study guide and breaking the biochemistry course into a number of units each to be mastered at the student's own pace. (Editor)

Network Centric Warfare Case Study: U.S. V Corps and 3rd Infantry Division (Mechanized) During Operation Iraqi Freedom Combat Operations (Mar-Apr 2003). Volume 3. Network Centric Warfare Insights

DTIC Science & Technology

2003-01-01

OPSEC), military deception, psychological operations (PSYOPS), special information operations (IO), information assurance, physical security...nonlethal effects, such as operational 8 Network Centric Warfare Case Study security (OPSEC), military deception, psychological operations (PSYOP...Support Operations Group ASR Alternate Supply Route; or, Ammunition Supply Rate ATACMS Army Tactical Missile System ATARS Advanced

Abnormal hepatic biochemistries and clinical liver disease in patients with primary Sjögren's syndrome.

PubMed

Montaño-Loza, Aldo J; Crispín-Acuña, José Carlos; Remes-Troche, José María; Uribe, Misael

2007-01-01

Patients with primary Sjögren's syndrome may present liver involvement. Our goals were to establish the prevalence of abnormal hepatic biochemistries and clinical liver disease in patients with primary Sjögren's syndrome and correlate their presence with other clinical and laboratory features. Ninety-five patients with diagnosis of primary Sjögren's syndrome were studied. Data on gender, age, clinical features, liver biochemistries, tests of inflammation and autoimmunity, and concomitant diseases were collected. Forty-two patients (44%) had abnormal hepatic biochemistries, and of these 19 patients (20%) had clinical liver disease. Patients with abnormal hepatic biochemistries had higher frequency of autoimmune hypotiroidism, arthritis, vasculitis, Raynaud's phenomenon, higher sedimentation rate,and higher frequency of antinuclear and antimitochondrial antibodies than patients with normal liver biochemistries (P < 0.05 for each). Patients with clinical liver disease had higher frequency of arthritis, vasculitis, and higher frequency of antimitochondrial antibodies than patients without clinical liver disease (P < 0.05 for each). Twenty-one patients had diagnosis of a specific liver disease, such as hepatitis C virus infection (n = 11), autoimmune hepatitis (n = 2), primary biliary cirrhosis (n =5),nonalcoholic fatty liver disease (n = 2), and hepatitis B virus infection (n = 1). In half of patients with liver involvement a definitive cause could not be identified. Liver involvement is frequently found in patients with primary Sjögren's syndrome, and its presence is associated with clinical features of systemic disease, and markers of autoimmunity and inflammation. There may be a subgroup of patients with liver involvement secondary to primary Sjögren's syndrome.

Enhancing Predictive Accuracy of Cardiac Autonomic Neuropathy Using Blood Biochemistry Features and Iterative Multitier Ensembles.

PubMed

Abawajy, Jemal; Kelarev, Andrei; Chowdhury, Morshed U; Jelinek, Herbert F

2016-01-01

Blood biochemistry attributes form an important class of tests, routinely collected several times per year for many patients with diabetes. The objective of this study is to investigate the role of blood biochemistry for improving the predictive accuracy of the diagnosis of cardiac autonomic neuropathy (CAN) progression. Blood biochemistry contributes to CAN, and so it is a causative factor that can provide additional power for the diagnosis of CAN especially in the absence of a complete set of Ewing tests. We introduce automated iterative multitier ensembles (AIME) and investigate their performance in comparison to base classifiers and standard ensemble classifiers for blood biochemistry attributes. AIME incorporate diverse ensembles into several tiers simultaneously and combine them into one automatically generated integrated system so that one ensemble acts as an integral part of another ensemble. We carried out extensive experimental analysis using large datasets from the diabetes screening research initiative (DiScRi) project. The results of our experiments show that several blood biochemistry attributes can be used to supplement the Ewing battery for the detection of CAN in situations where one or more of the Ewing tests cannot be completed because of the individual difficulties faced by each patient in performing the tests. The results show that AIME provide higher accuracy as a multitier CAN classification paradigm. The best predictive accuracy of 99.57% has been obtained by the AIME combining decorate on top tier with bagging on middle tier based on random forest. Practitioners can use these findings to increase the accuracy of CAN diagnosis.

Revolution or Evolution: Combined Arms Warfare in the Twenty-First Century

DTIC Science & Technology

1999-06-04

of the relationship of technological development and its impact on the military . Technology has always been a major factor in the initiation, execution...this technology revolutionized warfare? 1 There has been much argument lately that the U.S. Army is participating in the latest revolution in military ...their impact on strategic concerns: The emergence of technology that has military applications is accelerating, but revolutionary changes in military

History of Biochemistry at the University of Geneva From the Boulevard des Philosophes to Quai Ernest-Ansermet.

PubMed

Deshusses, Jacques; Riezman, Howard

2009-12-01

A brief account of the developments in biochemistry at the Faculty of Science of the University of Geneva is given from its emergence from organic chemistry at the Ancienne Ecole de chimie to today's Department of Biochemistry at the Section de chimie et biochimie.

Conventional Warfare and United States Military Involvement in Latin America: Early Adolescents' Views.

ERIC Educational Resources Information Center

Roscoe, Bruce; And Others

1988-01-01

Assessed adolescents' views concerning conventional war and compared views to those of adolescents 15 years ago. Surveyed 362 seventh graders regarding conventional warfare and United States military involvement in Latin America. Compared to adolescents in 1971, adolescents in 1986 were somewhat more accepting of war. Many were skeptical of…

Adjusting a biochemistry course for physical education majors: A case study.

PubMed

da Costa, Caetano; Torres, Bayardo B

2004-03-01

The purpose of this study was to investigate and analyze the events responsible for curricular characteristics that lead to positive outcomes in university teaching using a biochemistry course taught to physical education students as a model. The research was carried out as a case study, supported by questionnaires, classroom observation, document analysis, and interviews. The overall analyses of obtained data were validated by means of triangulation protocols, which proved the following reasons for the course achievements: 1) teaching staff deeply committed to the course; 2) contents adaptation to students' careers; 3) gradual adjustment of the teaching strategies and evaluation tools; 4) valorization of formative evaluation; and 5) providing a suitable affective milieu. Copyright © 2004 International Union of Biochemistry and Molecular Biology, Inc.

Chance and necessity in biochemistry: implications for the search for extraterrestrial biomarkers in Earth-like environments.

PubMed

Davila, Alfonso F; McKay, Christopher P

2014-06-01

In this paper, we examine a restricted subset of the question of possible alien biochemistries. That is, we look into how different life might be if it emerged in environments similar to that required for life on Earth. We advocate a principle of chance and necessity in biochemistry. According to this principle, biochemistry is in some fundamental way the sum of two processes: there is an aspect of biochemistry that is an endowment from prebiotic processes, which represents the necessity, plus an aspect that is invented by the process of evolution, which represents the chance. As a result, we predict that life originating in extraterrestrial Earth-like environments will share biochemical motifs that can be traced back to the prebiotic world but will also have intrinsic biochemical traits that are unlikely to be duplicated elsewhere as they are combinatorially path-dependent. Effective and objective strategies to search for biomarkers, and evidence for a second genesis, on planets with Earth-like environments can be built based on this principle.

Undergraduate Performance in Solving Ill-Defined Biochemistry Problems

PubMed Central

Sensibaugh, Cheryl A.; Madrid, Nathaniel J.; Choi, Hye-Jeong; Anderson, William L.; Osgood, Marcy P.

2017-01-01

With growing interest in promoting skills related to the scientific process, we studied performance in solving ill-defined problems demonstrated by graduating biochemistry majors at a public, minority-serving university. As adoption of techniques for facilitating the attainment of higher-order learning objectives broadens, so too does the need to appropriately measure and understand student performance. We extended previous validation of the Individual Problem Solving Assessment (IPSA) and administered multiple versions of the IPSA across two semesters of biochemistry courses. A final version was taken by majors just before program exit, and student responses on that version were analyzed both quantitatively and qualitatively. This mixed-methods study quantifies student performance in scientific problem solving, while probing the qualitative nature of unsatisfactory solutions. Of the five domains measured by the IPSA, we found that average graduates were only successful in two areas: evaluating given experimental data to state results and reflecting on performance after the solution to the problem was provided. The primary difficulties in each domain were quite different. The most widespread challenge for students was to design an investigation that rationally aligned with a given hypothesis. We also extend the findings into pedagogical recommendations. PMID:29180350

Detection of warfare agents in liquid foods using the brine shrimp lethality assay.

PubMed

Lumor, Stephen E; Diez-Gonzalez, Francisco; Labuza, Theodore P

2011-01-01

The brine shrimp lethality assay (BSLA) was used for rapid and non-specific detection of biological and chemical warfare agents at concentrations considerably below that which will cause harm to humans. Warfare agents detected include T-2 toxin, trimethylsilyl cyanide, and commercially available pesticides such as dichlorvos, diazinon, dursban, malathion, and parathion. The assay was performed by introducing 50 μL of milk or orange juice contaminated with each analyte into vials containing 10 freshly hatched brine shrimp nauplii in seawater. This was incubated at 28 °C for 24 h, after which mortality was determined. Mortality was converted to probits and the LC(50) was determined for each analyte by plotting probits of mortality against analyte concentration (log(10)). Our findings were the following: (1) the lethal effects of toxins dissolved in milk were observed, with T-2 toxin being the most lethal and malathion being the least, (2) except for parathion, the dosage (based on LC(50)) of analyte in a cup of milk (200 mL) consumed by a 6-y-old (20 kg) was less than the respective published rat LD(50) values, and (3) the BSLA was only suitable for detecting toxins dissolved in orange juice if incubation time was reduced to 6 h. Our results support the application of the BSLA for routine, rapid, and non-specific prescreening of liquid foods for possible sabotage by an employee or an intentional bioterrorist act. Practical Application: The findings of this study strongly indicate that the brine shrimp lethality assay can be adapted for nonspecific detection of warfare agents or toxins in food at any point during food production and distribution.

Using Adobe Flash animations of electron transport chain to teach and learn biochemistry.

PubMed

Teplá, Milada; Klímová, Helena

2015-01-01

Teaching the subject of the electron transport chain is one of the most challenging aspects of the chemistry curriculum at the high school level. This article presents an educational program called "Electron Transport Chain" which consists of 14 visual animations including a biochemistry quiz. The program was created in the Adobe Flash CS3 Professional animation program and is designed for high school chemistry students. Our goal is to develop educational materials that facilitate the comprehension of this complex subject through dynamic animations which show the course of the electron transport chain and simultaneously explain its nature. We record the process of the electron transport chain, including connections with oxidative phosphorylation, in such a way as to minimize the occurrence of discrepancies in interpretation. The educational program was evaluated in high schools through the administration of a questionnaire, which contained 12 opened-ended items and which required participants to evaluate the graphics of the animations, chemical content, student preferences, and its suitability for high school biochemistry teaching. © 2015 The International Union of Biochemistry and Molecular Biology.

HEMATOLOGY, SERUM BIOCHEMISTRY, AND URINALYSIS VALUES IN THE ADULT GIANT PANDA ( AILUROPODA MELANOLEUCA).

PubMed

Burrell, Caitlin; Zhang, Hemin; Li, Desheng; Wang, Chengdong; Li, Caiwu; Aitken-Palmer, Copper

2017-12-01

The giant panda ( Ailuropoda melanoleuca) is a high-profile threatened species with individuals in captivity worldwide. As a result of advances in captive animal management and veterinary medicine, the ex situ giant panda population is aging, and improved understanding of age-related changes is necessary. Urine and blood samples were collected in April and July 2015 and analyzed for complete blood count, serum biochemistry, and biochemical and microscopic urine analysis for all individuals sampled ( n = 7, 7-16 yr of age) from giant panda housed at the China Research and Conservation Centre for the Giant Panda in Bifengxia, Sichuan Province, China. Hematology and serum biochemistry values were similar to those previously reported for giant panda aged 2-20 yr and to Species360 (formerly International Species Information System) values. Urine was overall dilute (urine specific gravity range: 1.001-1.021), acellular, and acidic (pH range: 6-7). This is the first report of hematologic and serum biochemistry, with associated urinalysis values, in the giant panda aged 7-16 yr.

U.S. Army Chemical Corps Historical Studies, Gas Warfare in World War I: The 5th Division Captures Frapelle, August 1918

DTIC Science & Technology

1958-03-01

U. S . ARMY CHEMICAL CORPS HISTORICAL STUDIES GAS WARFARE IN WORLD WAR I THE 5t1h DIVISION CAPTURES FRAPELLF, 00 August 1918 CTD Offce t e Chef Ch mal...j JNSPECrrr / D~iJ f ; t t] GA o WARFARE IN WORLD WAR I By - --------- St ixdy Number 7 t:a . • ’ I : : . .. s U.S. ARMY CHEIICAL CORPS [ist...Analysi s Concerning the Weight of Shell . . . . . . . ... . 38 The Cost of Frapelle . . . . . . . . . . . .. 41 Medical Department Comments

The New Biochemistry: Blending the Traditional with the Other.

ERIC Educational Resources Information Center

Boyer, Rodney

2000-01-01

Points out the difficulties in designing and presenting a modern chemistry course with an overabundance of topics to cover in a limited amount of class time. Presents a model syllabi for biochemistry majors and the shorter survey course for non-majors, usually consisting of health professionals and biological science majors. (Contains 24…

Waste minimization opportunity assessment: Naval Undersea Warfare Engineering Station, Keyport, Washington. Project summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The Environmental Protection Agency (EPA) has developed a systematic approach to identify, select and implement options to reduce or eliminate hazardous waste. The report describes the application of the waste minimization assessment procedures to a torpedo maintenance facility at the Naval Undersea Warfare Engineering Station in Keyport, WA (NUWES Keyport).

Integrated Biological Warfare Technology Platform (IBWTP). Intelligent Software Supporting Situation Awareness, Response, and Operations

DTIC Science & Technology

2007-01-01

15 4.2.3. Users of Systems for Combating Biological Warfare ................................ 16 4.2.4...21 4.3.1. Existing Biosurveillance Systems .............................................................. 22 4.3.2. Automatic Integration...74 6.4.4. Multi-Agent System Management System (MMS).................................... 75 6.4.5. Agent Glossary

Naval Special Warfare: Identifying and Prioritizing Core Attributes of the Profession

DTIC Science & Technology

2014-12-01

literature review supports the need for research that is designed to advance the NSW profession. Analytic rigor could inform how NSW should refine its...B. SKILLS REQUIRED - WHAT (QUESTIONS 10–25, 26, 30) This research was designed to answer the following question: “What are the practical skills...NSW PRODEV: Naval Special Warfare Professional Development This research is designed to answer the following question. What are the practical

Surface Warfare Junior Officer Retention; Spouses’ Influence on Career Decisions

DTIC Science & Technology

1981-08-01

1974), and (4) Self - esteem ( Rosenberg , 1965 ). In November 1978, the survey questionnaire was mailed to a random sample of 691 male surface warfare... Rosenberg , M. Society and the adolescent self -image. Princeton, NJ: Princeton University Press, 1965 . 29 ___________ Stumpf, S. 5., & Kieckhaefer, N...these services with no loss in st.- is or self - esteem . If this approach is not sLIccessful, a separate branch of Family Service. may be required

A national comparison of biochemistry and molecular biology capstone experiences.

PubMed

Aguanno, Ann; Mertz, Pamela; Martin, Debra; Bell, Ellis

2015-01-01

Recognizing the increasingly integrative nature of the molecular life sciences, the American Society for Biochemistry and Molecular Biology (ASBMB) recommends that Biochemistry and Molecular Biology (BMB) programs develop curricula based on concepts, content, topics, and expected student outcomes, rather than courses. To that end, ASBMB conducted a series of regional workshops to build a BMB Concept Inventory containing validated assessment tools, based on foundational and discipline-specific knowledge and essential skills, for the community to use. A culminating activity, which integrates the educational experience, is often part of undergraduate molecular life science programs. These "capstone" experiences are commonly defined as an attempt to measure student ability to synthesize and integrate acquired knowledge. However, the format, implementation, and approach to outcome assessment of these experiences are quite varied across the nation. Here we report the results of a nation-wide survey on BMB capstone experiences and discuss this in the context of published reports about capstones and the findings of the workshops driving the development of the BMB Concept Inventory. Both the survey results and the published reports reveal that, although capstone practices do vary, certain formats for the experience are used more frequently and similarities in learning objectives were identified. The use of rubrics to measure student learning is also regularly reported, but details about these assessment instruments are sparse in the literature and were not a focus of our survey. Finally, we outline commonalities in the current practice of capstones and suggest the next steps needed to elucidate best practices. © 2015 The International Union of Biochemistry and Molecular Biology.

Audio Podcasting in a Tablet PC-Enhanced Biochemistry Course

ERIC Educational Resources Information Center

Lyles, Heather; Robertson, Brian; Mangino, Michael; Cox, James R.

2007-01-01

This report describes the effects of making audio podcasts of all lectures in a large, basic biochemistry course promptly available to students. The audio podcasts complement a previously described approach in which a tablet PC is used to annotate PowerPoint slides with digital ink to produce electronic notes that can be archived. The fundamentals…

The Use of Multiple Tools for Teaching Medical Biochemistry

ERIC Educational Resources Information Center

Se, Alexandre B.; Passos, Renato M.; Ono, Andre H.; Hermes-Lima, Marcelo

2008-01-01

In this work, we describe the use of several strategies employing the philosophies of active learning and problem-based learning (PBL) that may be used to improve the teaching of metabolic biochemistry to medical and nutritional undergraduate students. The main activities are as follows: 1) a seminar/poster system in a mini-congress format (using…

Active Learning of Biochemistry Made Easy (for the Teacher)

ERIC Educational Resources Information Center

Bobich, Joseph A.

2008-01-01

This active learning pedagogical technique aims to improve students' learning in a two-semester, upper-division biochemistry course sequence in which the vast majority of students enrolled will continue on to medical or graduate schools. Instead of lecturing, the Instructor moves to the side of the room, thereby becoming "the guide on the side".…

Uncovering Students' Incorrect Ideas about Foundational Concepts for Biochemistry

ERIC Educational Resources Information Center

Villafane, Sachel M.; Loertscher, Jennifer; Minderhout, Vicky; Lewis, Jennifer E.

2011-01-01

This paper presents preliminary data on how an assessment instrument with a unique structure can be used to identify common incorrect ideas from prior coursework at the beginning of a biochemistry course, and to determine whether these ideas have changed by the end of the course. The twenty-one multiple-choice items address seven different…

Promoting active learning of graduate student by deep reading in biochemistry and microbiology pharmacy curriculum.

PubMed

Peng, Ren

2017-07-08

To promote graduate students' active learning, deep reading of high quality papers was done by graduate students enrolled in biochemistry and microbiology pharmacy curriculum offered by college of life science, Jiangxi Normal University from 2013 to 2015. The number of graduate students, who participated in the course in 2013, 2014, and 2015 were eleven, thirteen and fifteen, respectively. Through deep reading of papers, presentation, and group discussion in the lecture, these graduate students have improved their academic performances effectively, such as literature search, PPT document production, presentation management, specialty document reading, academic inquiry, and analytical and comprehensive ability. The graduate students also have increased their understanding level of frontier research, scientific research methods, and experimental methods. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(4):305-312, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

Strategic Choice: United States Special Forces’ Comparative Advantage in Irregular Warfare

DTIC Science & Technology

2017-03-01

UNITED STATES SPECIAL FORCES’ COMPARATIVE ADVANTAGE IN IRREGULAR WARFARE by Steven F. Payne March 2017 Thesis Advisor: Hy S. Rothstein...REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE STRATEGIC CHOICE: UNITED STATES SPECIAL FORCES’ COMPARATIVE ADVANTAGE IN...methodology, this thesis concludes that U.S. Army Special Forces have a comparative advantage over conventional forces to provide the National Command

Israel’s Second Lebanon War: A Failure of Afghan Model Warfare?

DTIC Science & Technology

2007-05-10

Israeli experience in the Second Lebanon War will be compared against the American experience in Afghanistan as analyzed by Dr. Stephen Biddle in his...Biddle’s arguments regarding the so-called “Afghan Model” reinforces the validity of the conclusions Dr. Biddle derives regarding the U.S. success in...an irregular guerilla force. 2 Stephen Biddle , Afghanistan and the Future of Warfare

Biochemistry of fish stomach chitinase.

PubMed

Ikeda, Mana; Kakizaki, Hiromi; Matsumiya, Masahiro

2017-11-01

Fish are reported to exhibit chitinase activity in the stomach. Analyses of fish stomach chitinases have shown that these enzymes have the physiological function of degrading chitinous substances ingested as diets. Osteichthyes, a group that includes most of the fishes, have several chitinases in their stomachs. From a phylogenetic analysis of the chitinases of vertebrates, these particular molecules were classified into a fish-specific group and have different substrate specificities, suggesting that they can degrade ingested chitinous substances efficiently. On the other hand, it has been suggested that coelacanth (Sarcopterygii) and shark (Chondrichthyes) have a single chitinase enzyme in their stomachs, which shows multiple functions. This review focuses on recent research on the biochemistry of fish stomach chitinases. Copyright © 2017 Elsevier B.V. All rights reserved.

Titration of Alanine Monitored by NMR Spectroscopy: A Biochemistry Laboratory Experiment

ERIC Educational Resources Information Center

Waller, Francis J.; And Others

1977-01-01

The experiment described here involves simultaneous monitoring of pH and NMR chemical shifts during an aqueous titration of alpha- and beta-alanine. This experiment is designed for use in an undergraduate biochemistry course. (MR)

Reactivity I: A Foundation-Level Course for Both Majors and Nonmajors in Integrated Organic, Inorganic, and Biochemistry

ERIC Educational Resources Information Center

Schaller, Chris P.; Graham, Kate J.; Johnson, Brian J.; Jones, T. Nicholas; McIntee, Edward J.

2015-01-01

A foundation level course is presented that integrates aspects of organic, inorganic and biochemistry in the context of reactivity. The course was designed to serve majors in chemistry and other sciences (biochemistry, biology, nutrition), as well as nursing and pre-health professions students. Themes of the course were designed to highlight a…

Chance and Necessity in Biochemistry: Implications for the Search for Extraterrestrial Biomarkers in Earth-like Environments

PubMed Central

McKay, Christopher P.

2014-01-01

Abstract In this paper, we examine a restricted subset of the question of possible alien biochemistries. That is, we look into how different life might be if it emerged in environments similar to that required for life on Earth. We advocate a principle of chance and necessity in biochemistry. According to this principle, biochemistry is in some fundamental way the sum of two processes: there is an aspect of biochemistry that is an endowment from prebiotic processes, which represents the necessity, plus an aspect that is invented by the process of evolution, which represents the chance. As a result, we predict that life originating in extraterrestrial Earth-like environments will share biochemical motifs that can be traced back to the prebiotic world but will also have intrinsic biochemical traits that are unlikely to be duplicated elsewhere as they are combinatorially path-dependent. Effective and objective strategies to search for biomarkers, and evidence for a second genesis, on planets with Earth-like environments can be built based on this principle. Key Words: Origin of life—Biomarkers—Exobiology—Extraterrestrial life—Prebiotic chemistry. Astrobiology 14, 534–540. PMID:24867145

Plasma flame for mass purification of contaminated air with chemical and biological warfare agents

NASA Astrophysics Data System (ADS)

Uhm, Han S.; Shin, Dong H.; Hong, Yong C.

2006-09-01

An elimination of airborne simulated chemical and biological warfare agents was carried out by making use of a plasma flame made of atmospheric plasma and a fuel-burning flame, which can purify the interior air of a large volume in isolated spaces such as buildings, public transportation systems, and military vehicles. The plasma flame generator consists of a microwave plasma torch connected in series to a fuel injector and a reaction chamber. For example, a reaction chamber, with the dimensions of a 22cm diameter and 30cm length, purifies an airflow rate of 5000lpm contaminated with toluene (the simulated chemical agent) and soot from a diesel engine (the simulated aerosol for biological agents). Large volumes of purification by the plasma flame will free mankind from the threat of airborne warfare agents. The plasma flame may also effectively purify air that is contaminated with volatile organic compounds, in addition to eliminating soot from diesel engines as an environmental application.

A Guide to Using Case-Based Learning in Biochemistry Education

ERIC Educational Resources Information Center

Kulak, Verena; Newton, Genevieve

2014-01-01

Studies indicate that the majority of students in undergraduate biochemistry take a surface approach to learning, associated with rote memorization of material, rather than a deep approach, which implies higher cognitive processing. This behavior relates to poorer outcomes, including impaired course performance and reduced knowledge retention. The…

Using Myoglobin Denaturation to Help Biochemistry Students Understand Protein Structure

ERIC Educational Resources Information Center

Miao, Yilan; Thomas, Courtney L.

2017-01-01

Analyzing and understanding data directly from primary literature can be a daunting task for undergraduates. However, if information is put into context, students will be more successful when developing data analysis skills. A classroom activity is presented using protein denaturation to help undergraduate biochemistry students examine myoglobin…

An Integrated Strategy for Teaching Biochemistry to Biotechnology Specialty Students

ERIC Educational Resources Information Center

Ouyang, Liming; Ou, Ling; Zhang, Yuanxing

2007-01-01

The faculty of biochemistry established an integrated teaching strategy for biotechnology specialty students, by intermeshing the case-study method, web-assistant teaching, and improved lecture format with a brief content and multimedia courseware. Teaching practice showed that the integrated teaching strategy could retain the best features of…

Creation and implementation of a flipped jigsaw activity to stimulate interest in biochemistry among medical students.

PubMed

Williams, Charlene; Perlis, Susan; Gaughan, John; Phadtare, Sangita

2018-05-06

Learner-centered pedagogical methods that are based on clinical application of basic science concepts through active learning and problem solving are shown to be effective for improving knowledge retention. As the clinical relevance of biochemistry is not always apparent to health-profession students, effective teaching of medical biochemistry should highlight the implications of biochemical concepts in pathology, minimize memorization, and make the concepts memorable for long-term retention. Here, we report the creation and successful implementation of a flipped jigsaw activity that was developed to stimulate interest in learning biochemistry among medical students. The activity combined the elements of a flipped classroom for learning concepts followed by a jigsaw activity to retrieve these concepts by solving clinical cases, answering case-based questions, and creating concept maps. The students' reception of the activity was very positive. They commented that the activity provided them an opportunity to review and synthesize information, helped to gage their learning by applying this information and work with peers. Students' improved performance especially for answering the comprehension-based questions correctly in the postquiz as well as the depth of information included in the postquiz concept maps suggested that the activity helped them to understand how different clinical scenarios develop owing to deviations in basic biochemical pathways. Although this activity was created for medical students, the format of this activity can also be useful for other health-professional students as well as undergraduate and graduate students. © 2018 by The International Union of Biochemistry and Molecular Biology, 2018. © 2018 The International Union of Biochemistry and Molecular Biology.

A Survey on Faculty Perspectives on the Transition to a Biochemistry Course-Based Undergraduate Research Experience Laboratory

ERIC Educational Resources Information Center

Craig, Paul A.

2017-01-01

It will always remain a goal of an undergraduate biochemistry laboratory course to engage students hands-on in a wide range of biochemistry laboratory experiences. In 2006, our research group initiated a project for "in silico" prediction of enzyme function based only on the 3D coordinates of the more than 3800 proteins "of unknown…

Information Operations and Warfare: Fundamental Challenges for the 21st Century

DTIC Science & Technology

1997-05-01

Perritt, Jr., Access To The National Information Infrastructure, 30 WAKE FOREST L. REV. 51 (1995); John I. Alger, Declaring Information War, JANE’S...Sought For Info Warfare, COMPUTERWORLD, Jun. 5, 1995, at 55 [hereinafter New Laws]; John Arquilla & David Ronfeldt, Cyberwat is Coming!, COMPARATIVE...at 82. See also John T. Correll, Signs of a Revolution, AIR FORCE MAG., Aug. 1995, at 2 ("Over the years, there have been periodic innovations

Seeking Shadows in the Sky: The Strategy of Air Guerrilla Warfare

DTIC Science & Technology

2001-11-01

Structuring Air Power for the Small Air Force,” in Air Power Confronts an Unstable World, ed. Richard P. Hallion (London: Brassey’s, 1997), 181. 12...Santa Monica, Calif.: RAND, 1997), 207. 6. Air Commodore Andrew G. B. Vallance , “The Changing Nature of Air Warfare,” in Air Power Confronts an...Unstable World, ed. Richard P. Hallion (London: Brassey’s, 1997), xv; and Alan Stephens, The Implications of Modern Airpower for Defence Strategy, Air

Measuring the Operational Readiness of an Air Force Network Warfare Squadron

DTIC Science & Technology

2008-06-01

Abstract As part of its unit activation, the 315th Network Warfare Squadron (NWS) needed to measure and report its progression of unit readiness...NWS unit readiness should be measured and reported by SORTS Category Levels (C-Level) to support wartime missions, not by IOC and FOC milestones...This paper reviews SORTS computations and provides a case study of a notional Air Force NWS to propose that any new cyber squadron should report

An Empirical Examination of the Warfare Metaphor with Respect to Pre-Service Elementary Teachers

ERIC Educational Resources Information Center

Cobern, William W.; Loving, Cathleen C.; Davis, Edward B.; Terpstra, Jeff

2013-01-01

Since its origination in the late nineteenth century, the warfare metaphor has been used to characterize the relationship between science and religion, especially orthodox Christianity. Though thoroughly discredited by historians of science, the ideological descendants of Thomas Huxley, who spoke of science in quasi-religious terms, have kept the…

Planning an objective and need based curriculum: the logistics with reference to the undergraduate medical education in biochemistry.

PubMed

Ramasamy, Ramesh; Gopal, Niranjan; Srinivasan, A R; Murugaiyan, Sathish Babu

2013-03-01

The medical education is recently being transformed into several domains in order to adapt to the need and the value based academics which is required for the quality doctors who serve the community. Presently, the biochemistry curricula for the graduate students of medicine have been questioned by as many experts, because of their multiple lacunae. In this review, we would like to highlight the scenario which is related to the existing biochemistry curricula for graduate medical students, which have been followed in several medical schools and universities and we also hope to share our ideas for implementing objective and pragmatic curricula. Evidence based research, wherein the articles which are related to innovative teaching-learning tools are collected and the pros and cons which are related to the different methods analyzed in biochemistry point of view. Rapid changes in the content of the curriculum may not be required, but a gradual introduction of the novel approach and the methods of teaching biochemistry can be adopted into the curriculum.

Information Warfare: Legal, Regulatory, Policy and Organizational Considerations for Assurance. Second Edition.

DTIC Science & Technology

1996-07-04

of Information Warfare and Strategy graduated 32 students from its 10-month senior level (war college ) program on 12 June 1996. The event marked the...1989 prosecution of Robert Tappan Morris, a Cornell University graduate student who, on November 2, 1988, released a computer worm across the...2-25 2-2-1 Constitutional Amendments with Privacy Implications .................................... 2-28 2-2-2 Privacy and Access to Government

Teaching of Biochemistry in Medical School: A Well-Trodden Pathway?

ERIC Educational Resources Information Center

Mathews, Michael B.; Stagnaro-Green, Alex

2008-01-01

Biochemistry and molecular biology occupy a unique place in the medical school curriculum. They are frequently studied prior to medical school and are fundamental to the teaching of biomedical sciences in undergraduate medical education. These two circumstances, and the trend toward increased integration among the disciplines, have led to…

Osmotic Stressing, Membrane Leakage, and Fluorescence: An Introductory Biochemistry Demonstration

ERIC Educational Resources Information Center

Seu, Kalani J.

2015-01-01

A fluorescence demonstration is described that incorporates several fundamental aspects of an introductory biochemistry course. A variation of a known leakage assay is utilized to prepare vesicles containing a quenched fluorophore. The vesicles are exposed to several osmotic environments ranging from isotonic to hypotonic. The degree of vesicle…

Learning Medical School Biochemistry Through Self-Directed Case-Oriented Study.

ERIC Educational Resources Information Center

Morley, Colin G. D.; Blumberg, Phyllis

1987-01-01

Describes an alternative medical school curriculum for the first two years of preclinical basic science studies. Discusses student and faculty selection for the program. Details the format for teaching biochemistry in the Alternative Curriculum, including program structure, content organization and exams. Evaluates the success of the program. (CW)

An "in Silico" DNA Cloning Experiment for the Biochemistry Laboratory

ERIC Educational Resources Information Center

Elkins, Kelly M.

2011-01-01

This laboratory exercise introduces students to concepts in recombinant DNA technology while accommodating a major semester project in protein purification, structure, and function in a biochemistry laboratory for junior- and senior-level undergraduate students. It is also suitable for forensic science courses focused in DNA biology and advanced…

A Laboratory Course in Clinical Biochemistry Emphasizing Interest and Relevance

ERIC Educational Resources Information Center

Schwartz, Peter L.

1975-01-01

Ten laboratory experiments are described which are used in a successful clinical biochemistry laboratory course (e.g. blood alcohol, glucose tolerance, plasma triglycerides, coronary risk index, gastric analysis, vitamin C and E). Most of the experiments are performed on the students themselves using simple equipment with emphasis on useful…

50 years of comparative biochemistry: The legacy of Peter Hochachka.

PubMed

Buck, L T; Burness, G; Campbell, K L; Darveau, C-A; Driedzic, W; Guderley, H; McClelland, G B; Moon, T W; Moyes, C D; Schulte, P M

2018-02-28

Peter Hochachka was an early pioneer in the field of comparative biochemistry. He passed away in 2002 after 4 decades of research in the discipline. To celebrate his contributions and to coincide with what would have been his 80th birthday, a group of his former students organized a symposium that ran as a satellite to the 2017 Canadian Society of Zoologists annual meeting in Winnipeg, Manitoba (Canada). This Special Issue of CBP brings together manuscripts from symposium attendees and other authors who recognize the role Peter played in the evolution of the discipline. In this article, the symposium organizers and guest editors look back on his career, celebrating his many contributions to research, acknowledging his role in training of generations of graduate students and post-doctoral fellows in comparative biochemistry and physiology. Copyright © 2018. Published by Elsevier Inc.

Reactive skin decontamination lotion (RSDL) for the decontamination of chemical warfare agent (CWA) dermal exposure.

PubMed

Schwartz, M D; Hurst, C G; Kirk, M A; Reedy, S J D; Braue, E H

2012-08-01

Rapid decontamination of the skin is the single most important action to prevent dermal absorption of chemical contaminants in persons exposed to chemical warfare agents (CWA) and toxic industrial chemicals (TICs) as a result of accidental or intentional release. Chemicals on the skin may be removed by mechanical means through the use of dry sorbents or water. Recent interest in decontamination systems which both partition contaminants away from the skin and actively neutralize the chemical has led to the development of several reactive decontamination solutions. This article will review the recently FDA-approved Reactive Skin Decontamination Lotion (RSDL) and will summarize the toxicity and efficacy studies conducted to date. Evidence of RSDL's superior performance against vesicant and organophosphorus chemical warfare agents compared to water, bleach, and dry sorbents, suggests that RSDL may have a role in mass human exposure chemical decontamination in both the military and civilian arenas.

An Experiment Using Sucrose Density Gradients in the Undergraduate Biochemistry Laboratory.

ERIC Educational Resources Information Center

Turchi, Sandra L.; Weiss, Monica

1988-01-01

Describes an experiment to be performed in an undergraduate biochemistry laboratory that is based on a gradient centrifugation system employing a simple bench top centrifuge, a freezer, and frozen surcose gradient solution to separate macromolecules and subcellular components. (CW)