75 FR 1274 - Implantation or Injectable Dosage Form New Animal Drugs; Hyaluronate Sodium
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-11
... safety warning for use of hyaluronate sodium injectable solution in horses. DATES: This rule is effective... human food safety warning on product labeling. The supplemental NADA is approved as of December 11, 2009...
DOT National Transportation Integrated Search
1994-09-01
This report presents the results of research on human performance on detectable warning surfaces. The first portion of the report presents an evaluation of the underfoot detectability of nine detectable warning surfaces for persons having varied phys...
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Labeling of cosmetic products for which adequate..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.10 Labeling of cosmetic products for which adequate substantiation of safety has not been...
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Labeling of cosmetic products for which adequate..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.10 Labeling of cosmetic products for which adequate substantiation of safety has not been...
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Labeling of cosmetic products for which adequate..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.10 Labeling of cosmetic products for which adequate substantiation of safety has not been...
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Labeling of cosmetic products for which adequate..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.10 Labeling of cosmetic products for which adequate substantiation of safety has not been...
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Labeling of cosmetic products for which adequate..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.10 Labeling of cosmetic products for which adequate substantiation of safety has not been...
Security warning method and system for worker safety during live-line working
NASA Astrophysics Data System (ADS)
Jiang, Chilong; Zou, Dehua; Long, Chenhai; Yang, Miao; Zhang, Zhanlong; Mei, Daojun
2017-09-01
Live-line working is an essential part in the operations in an electric power system. Live-line workers are required to wear shielding clothing. Shielding clothing, however, acts as a closed environment for the human body. Working in a closed environment for a long time can change the physiological responses of the body and even endanger personal safety. According to the typical conditions of live-line working, this study synthesizes environmental factors related to shielding clothing and the physiological factors of the body to establish the heart rate variability index RMSSD and the comprehensive security warning index SWI. On the basis of both indices, this paper proposes a security warning method and system for the safety live-line workers. The system can monitor the real-time status of workers during live-line working to provide security warning and facilitate the effective safety supervision by the live operation center during actual live-line working.
DOT National Transportation Integrated Search
2008-02-01
The IVBSS program is a four-year, two-phase project to design and evaluate an integrated crash warning system for forward collision, lateral drift, lane-change merge, and curve speed warnings for both light vehicles and heavy trucks. This report, cov...
USDA-ARS?s Scientific Manuscript database
Floods have negative impacts on society, causing damages in infrastructures and industry, and in the worst cases, causing loss of human lives. Thus early and accurate warning is crucial to significantly reduce the impacts on public safety and economy. Reliable flood warning can be generated using ...
NASA Astrophysics Data System (ADS)
Riyahi, Pouria
This thesis is part of current research at Center for Intelligence Systems Research (CISR) at The George Washington University for developing new in-vehicle warning systems via Brain-Computer Interfaces (BCIs). The purpose of conducting this research is to contribute to the current gap between BCI and in-vehicle safety studies. It is based on the premise that accurate and timely monitoring of human (driver) brain's signal to external stimuli could significantly aide in detection of driver's intentions and development of effective warning systems. The thesis starts with introducing the concept of BCI and its development history while it provides a literature review on the nature of brain signals. The current advancement and increasing demand for commercial and non-medical BCI products are described. In addition, the recent research attempts in transportation safety to study drivers' behavior or responses through brain signals are reviewed. The safety studies, which are focused on employing a reliable and practical BCI system as an in-vehicle assistive device, are also introduced. A major focus of this thesis research has been on the evaluation and development of the signal processing algorithms which can effectively filter and process brain signals when the human subject is subjected to Visual LED (Light Emitting Diodes) stimuli at different frequencies. The stimulated brain generates a voltage potential, referred to as Steady-State Visual Evoked Potential (SSVEP). Therefore, a newly modified analysis algorithm for detecting the brain visual signals is proposed. These algorithms are designed to reach a satisfactory accuracy rate without preliminary trainings, hence focusing on eliminating the need for lengthy training of human subjects. Another important concern is the ability of the algorithms to find correlation of brain signals with external visual stimuli in real-time. The developed analysis models are based on algorithms which are capable of generating results for real-time processing of BCI devices. All of these methods are evaluated through two sets of recorded brain signals which were recorded by g.TEC CO. as an external source and recorded brain signals during our car driving simulator experiments. The final discussion is about how the presence of an SSVEP based warning system could affect drivers' performances which is defined by their reaction distance and Time to Collision (TTC). Three different scenarios with and without warning LEDs were planned to measure the subjects' normal driving behavior and their performance while they use a warning system during their driving task. Finally, warning scenarios are divided into short and long warning periods without and with informing the subjects, respectively. The long warning period scenario attempts to determine the level of drivers' distraction or vigilance during driving. The good outcome of warning scenarios can bridge between vehicle safety studies and online BCI system design research. The preliminary results show some promise of the developed methods for in-vehicle safety systems. However, for any decisive conclusion that considers using a BCI system as a helpful in-vehicle assistive device requires far deeper scrutinizing.
Basic Collision Warning and Driver Information Systems: Human Factors Research Needs
DOT National Transportation Integrated Search
1998-11-01
As part of the U.S. Department of Transportation's Intelligent Vehicle Initiative (IVI) program, the Federal Highway Administration (FHWA) investigated the human factors research needs for integrating in-vehicle safety and driver information technolo...
Improving tractor safety warnings: readability is missing.
Tebeaux, E
2010-07-01
Research on tractor safety has not focused on user manuals. This study focuses on tractor operator manuals, specifically safety warnings, selected from the files of the Tractor Test facility at University of Nebraska-Lincoln. Analysis of many common warnings, based on readability and legibility research, shows that many warnings contain excessive information, confusing visuals and safety icons, poor document design, and illegible typefaces. The result is unreadable warnings that do not communicate quickly and correctly, and discourage readers rather than clarify critical information. Many tractor operator warnings are cluttered, "over-written," and contain information needed to protect the manufacturer rather than to inform operators. What is needed is a careful analysis and revision of many safety warnings with the goal of encouraging operators to read the warnings and follow their message.
Tire aging: a human factors analysis of failure to warn and inform.
Wogalter, Michael S; Laughery, Kenneth R
2012-01-01
A scenario of an automotive accident caused by tire failure is given followed by a human factors analysis of the information available to consumers on tire aging. Consumers have not been told that the age of the tire is a safety concern. It is not easy to decode the date of manufacture on tires. More publicity and prominent warnings are needed to communicate the dangers of older tires. Also, better ways to present the date of manufacture so that consumers can more easily and accurately assess tire age are needed.
Evaluation of Pre-marketing Factors to Predict Post-marketing Boxed Warnings and Safety Withdrawals.
Schick, Andreas; Miller, Kathleen L; Lanthier, Michael; Dal Pan, Gerald; Nardinelli, Clark
2017-06-01
An important goal in drug regulation is understanding serious safety issues with new drugs as soon as possible. Achieving this goal requires us to understand whether information provided during the Food and Drug Administration (FDA) drug review can predict serious safety issues that are usually identified after the product is approved. However, research on this topic remains understudied. In this paper, we examine whether any pre-marketing drug characteristics are associated with serious post-marketing safety actions. We study this question using an internal FDA database containing every new small molecule drug submitted to the FDA's Center for Drug Evaluation and Research (CDER) on or after November 21, 1997, and approved and commercially launched before December 31, 2009. Serious post-marketing safety actions include whether these drugs ever experienced either a post-marketing boxed warning or a withdrawal from the market due to safety concerns. A random effects logistic regression model was used to test whether any pre-marketing characteristics were associated with either post-marketing safety action. A total of 219 new molecular entities were analyzed. Among these drugs, 11 experienced a safety withdrawal and 30 received boxed warnings by July 31, 2016. Contrary to prevailing hypotheses, we find that neither clinical trial sample sizes nor review time windows are associated with the addition of a post-marketing boxed warning or safety withdrawal. However, we do find that new drugs approved with either a boxed warning or priority review are more likely to experience post-marketing boxed warnings. Furthermore, drugs approved with boxed warnings tend to receive post-marketing boxed warnings resulting from new safety information that are unrelated to the original warning. Drugs approved with a boxed warning are 3.88 times more likely to receive a post-marketing boxed warning, while drugs approved with a priority review are 3.51 times more likely to receive a post-marketing boxed warning. Although drugs approved with a boxed warning or priority review are more likely to experience serious post-marketing safety events, other information provided during the FDA drug review that is easy to quantify is generally not associated with post-marketing safety events. It appears that these post-marketing events are not discernible during a pre-marketing review and therefore might not be avoidable using current review data.
Aircraft Cabin Turbulence Warning Experiment
NASA Technical Reports Server (NTRS)
Bogue, Rodney K.; Larcher, Kenneth
2006-01-01
New turbulence prediction technology offers the potential for advance warning of impending turbulence encounters, thereby allowing necessary cabin preparation time prior to the encounter. The amount of time required for passengers and flight attendants to be securely seated (that is, seated with seat belts fastened) currently is not known. To determine secured seating-based warning times, a consortium of aircraft safety organizations have conducted an experiment involving a series of timed secured seating trials. This demonstrative experiment, conducted on October 1, 2, and 3, 2002, used a full-scale B-747 wide-body aircraft simulator, human passenger subjects, and supporting staff from six airlines. Active line-qualified flight attendants from three airlines participated in the trials. Definitive results have been obtained to provide secured seating-based warning times for the developers of turbulence warning technology
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-12
... the second experiment will evaluate the lack of effectiveness in current audible warnings designed to...: Title: Recruitment of human subjects for observational experiments regarding keyless ignition controls... motor vehicle safety standards (FMVSSs). Human factors observational experiments are proposed to support...
Environmental Change & Fragile States Early Warning and Intervention
2011-05-12
data needed , and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of this...power to effectively meet the most challenging international objectives 7 Addressing Basic Human Needs Self- Actualization Ego (Esteem) Social...Belonging) Safety/Security Physiological Physical survival needs : water, food, shelter, warmth, sleep, etc. Physical safety, economic security, freedom
49 CFR 193.2917 - Warning signs.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 3 2012-10-01 2012-10-01 false Warning signs. 193.2917 Section 193.2917 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Security § 193.2917 Warning signs. (a) Warning signs must be conspicuously placed...
49 CFR 193.2917 - Warning signs.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 3 2011-10-01 2011-10-01 false Warning signs. 193.2917 Section 193.2917 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Security § 193.2917 Warning signs. (a) Warning signs must be conspicuously placed...
49 CFR 193.2917 - Warning signs.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 3 2013-10-01 2013-10-01 false Warning signs. 193.2917 Section 193.2917 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Security § 193.2917 Warning signs. (a) Warning signs must be conspicuously placed...
49 CFR 193.2917 - Warning signs.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 3 2014-10-01 2014-10-01 false Warning signs. 193.2917 Section 193.2917 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Security § 193.2917 Warning signs. (a) Warning signs must be conspicuously placed...
49 CFR 193.2917 - Warning signs.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 3 2010-10-01 2010-10-01 false Warning signs. 193.2917 Section 193.2917 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Security § 193.2917 Warning signs. (a) Warning signs must be conspicuously placed...
30 CFR 57.14214 - Train warnings.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Train warnings. 57.14214 Section 57.14214 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Equipment Safety Practices and Operational Procedures § 57.14214 Train warnings. A warning that is audible...
30 CFR 56.14214 - Train warnings.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Train warnings. 56.14214 Section 56.14214 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Safety Practices and Operational Procedures § 56.14214 Train warnings. A warning that is audible above...
30 CFR 56.14214 - Train warnings.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Train warnings. 56.14214 Section 56.14214 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Safety Practices and Operational Procedures § 56.14214 Train warnings. A warning that is audible above...
30 CFR 56.14214 - Train warnings.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Train warnings. 56.14214 Section 56.14214 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Safety Practices and Operational Procedures § 56.14214 Train warnings. A warning that is audible above...
30 CFR 56.14214 - Train warnings.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Train warnings. 56.14214 Section 56.14214 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Safety Practices and Operational Procedures § 56.14214 Train warnings. A warning that is audible above...
30 CFR 56.14214 - Train warnings.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Train warnings. 56.14214 Section 56.14214 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Safety Practices and Operational Procedures § 56.14214 Train warnings. A warning that is audible above...
30 CFR 57.14214 - Train warnings.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Train warnings. 57.14214 Section 57.14214 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Equipment Safety Practices and Operational Procedures § 57.14214 Train warnings. A warning that is audible...
30 CFR 57.14214 - Train warnings.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Train warnings. 57.14214 Section 57.14214 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Equipment Safety Practices and Operational Procedures § 57.14214 Train warnings. A warning that is audible...
30 CFR 57.14214 - Train warnings.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Train warnings. 57.14214 Section 57.14214 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Equipment Safety Practices and Operational Procedures § 57.14214 Train warnings. A warning that is audible...
30 CFR 57.14214 - Train warnings.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Train warnings. 57.14214 Section 57.14214 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Equipment Safety Practices and Operational Procedures § 57.14214 Train warnings. A warning that is audible...
14 CFR 29.1413 - Safety belts: passenger warning device.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Safety belts: passenger warning device. 29.1413 Section 29.1413 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF....1413 Safety belts: passenger warning device. (a) If there are means to indicate to the passengers when...
18 CFR 12.42 - Warning and safety devices.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Warning and safety devices. 12.42 Section 12.42 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.42 Warning and safety devices. To the...
14 CFR 29.1413 - Safety belts: passenger warning device.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Safety belts: passenger warning device. 29.1413 Section 29.1413 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF....1413 Safety belts: passenger warning device. (a) If there are means to indicate to the passengers when...
14 CFR 29.1413 - Safety belts: passenger warning device.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Safety belts: passenger warning device. 29.1413 Section 29.1413 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF....1413 Safety belts: passenger warning device. (a) If there are means to indicate to the passengers when...
18 CFR 12.42 - Warning and safety devices.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Warning and safety devices. 12.42 Section 12.42 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.42 Warning and safety devices. To the...
18 CFR 12.42 - Warning and safety devices.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Warning and safety devices. 12.42 Section 12.42 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.42 Warning and safety devices. To the...
14 CFR 29.1413 - Safety belts: passenger warning device.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Safety belts: passenger warning device. 29.1413 Section 29.1413 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF....1413 Safety belts: passenger warning device. (a) If there are means to indicate to the passengers when...
14 CFR 29.1413 - Safety belts: passenger warning device.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Safety belts: passenger warning device. 29.1413 Section 29.1413 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF....1413 Safety belts: passenger warning device. (a) If there are means to indicate to the passengers when...
18 CFR 12.42 - Warning and safety devices.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Warning and safety devices. 12.42 Section 12.42 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.42 Warning and safety devices. To the...
18 CFR 12.42 - Warning and safety devices.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Warning and safety devices. 12.42 Section 12.42 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.42 Warning and safety devices. To the...
21 CFR 201.316 - Drugs with thyroid hormone activity for human use; required warning.
Code of Federal Regulations, 2011 CFR
2011-04-01
..., use in the treatment of obesity, although their safety and effectiveness for that use have never been... with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients...
21 CFR 201.316 - Drugs with thyroid hormone activity for human use; required warning.
Code of Federal Regulations, 2010 CFR
2010-04-01
..., use in the treatment of obesity, although their safety and effectiveness for that use have never been... with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients...
21 CFR 201.316 - Drugs with thyroid hormone activity for human use; required warning.
Code of Federal Regulations, 2014 CFR
2014-04-01
..., use in the treatment of obesity, although their safety and effectiveness for that use have never been... with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients...
21 CFR 201.316 - Drugs with thyroid hormone activity for human use; required warning.
Code of Federal Regulations, 2012 CFR
2012-04-01
..., use in the treatment of obesity, although their safety and effectiveness for that use have never been... with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients...
21 CFR 201.316 - Drugs with thyroid hormone activity for human use; required warning.
Code of Federal Regulations, 2013 CFR
2013-04-01
..., use in the treatment of obesity, although their safety and effectiveness for that use have never been... with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients...
Liu, Yan; Xu, Zhen-Jun
2013-01-01
As a high-risk subindustry involved in construction projects, highway construction safety has experienced major developments in the past 20 years, mainly due to the lack of safe early warnings in Chinese construction projects. By combining the current state of early warning technology with the requirements of the State Administration of Work Safety and using case-based reasoning (CBR), this paper expounds on the concept and flow of highway construction safety early warnings based on CBR. The present study provides solutions to three key issues, index selection, accident cause association analysis, and warning degree forecasting implementation, through the use of association rule mining, support vector machine classifiers, and variable fuzzy qualitative and quantitative change criterion modes, which fully cover the needs of safe early warning systems. Using a detailed description of the principles and advantages of each method and by proving the methods' effectiveness and ability to act together in safe early warning applications, effective means and intelligent technology for a safe highway construction early warning system are established. PMID:24191134
Liu, Yan; Yi, Ting-Hua; Xu, Zhen-Jun
2013-01-01
As a high-risk subindustry involved in construction projects, highway construction safety has experienced major developments in the past 20 years, mainly due to the lack of safe early warnings in Chinese construction projects. By combining the current state of early warning technology with the requirements of the State Administration of Work Safety and using case-based reasoning (CBR), this paper expounds on the concept and flow of highway construction safety early warnings based on CBR. The present study provides solutions to three key issues, index selection, accident cause association analysis, and warning degree forecasting implementation, through the use of association rule mining, support vector machine classifiers, and variable fuzzy qualitative and quantitative change criterion modes, which fully cover the needs of safe early warning systems. Using a detailed description of the principles and advantages of each method and by proving the methods' effectiveness and ability to act together in safe early warning applications, effective means and intelligent technology for a safe highway construction early warning system are established.
An investigation of reports of Controlled Flight Toward Terrain (CFTT)
NASA Technical Reports Server (NTRS)
Porter, R. F.; Loomis, J. P.
1981-01-01
Some 258 reports from more than 23,000 documents in the files of the Aviation Safety Reporting System (ASRS) were found to be to the hazard of flight into terrain with no prior awareness by the crew of impending disaster. Examination of the reports indicate that human error was a casual factor in 64% of the incidents in which some threat of terrain conflict was experienced. Approximately two-thirds of the human errors were attributed to controllers, the most common discrepancy being a radar vector below the Minimum Vector Altitude (MVA). Errors by pilots were of a much diverse nature and include a few instances of gross deviations from their assigned altitudes. The ground proximity warning system and the minimum safe altitude warning equipment were the initial recovery factor in some 18 serious incidents and were apparently the sole warning in six reported instances which otherwise would most probably have ended in disaster.
Effect of directional speech warnings on road hazard detection.
Serrano, Jesús; Di Stasi, Leandro L; Megías, Alberto; Catena, Andrés
2011-12-01
In the last 2 decades, cognitive science and the transportation psychology field have dedicated a lot of effort to designing advanced driver support systems. Verbal warning systems are increasingly being implemented in modern automobiles in an effort to increase road safety. The study presented here investigated the impact of directional speech alert messages on the participants' speed to judge whether or not naturalistic road scenes depicted a situation of impending danger. Thirty-eight volunteers performed a computer-based key-press reaction time task. Findings indicated that semantic content of verbal warning signals can be used for increasing driving safety and improving hazard detection. Furthermore, the classical result regarding signal accuracy is confirmed: directional informative speech messages lead to faster hazard detection compared to drivers who received a high rate of false alarms. Notwithstanding some study limitations (lack of driver experience and low ecological validity), this evidence could provide important information for the specification of future Human-Machine-interaction (HMI) design guidelines.
Driver Support Functions under Resource-Limited Situations
NASA Astrophysics Data System (ADS)
Inagaki, Toshiyuki; Itoh, Makoto; Nagai, Yoshitomo
This paper reports results of an experiment with a driving simulator in order to answer the following question: What type of support should be given to an automobile driver when it is determined, via some monitoring method, that the driver's situation awareness may not be appropriate to a given traffic condition? This paper compares (a) warning type support in which an auditory warning is given to the driver to enhance situation awareness and (b) action type support in which an autonomous safety control is executed as a soft protection for avoiding an accident. Although the both types of driver support are effective, the former sometimes fail to assure safety, which suggests a limitation of the human locus of control assumption, while efficacy of the latter may be degraded by an incorrect human reasoning that can happen under uncertainty. This paper discusses viewpoints needed in the design of systems for supporting drivers in resource-limited situations in which information or time available for a driver is limited in a given traffic condition.
30 CFR 57.4101 - Warning signs.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Warning signs. 57.4101 Section 57.4101 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Prohibitions/precautions/housekeeping § 57.4101 Warning signs. Readily visible signs prohibiting smoking and...
30 CFR 56.4101 - Warning signs.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Warning signs. 56.4101 Section 56.4101 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Prohibitions/precautions/housekeeping § 56.4101 Warning signs. Readily visible signs prohibiting smoking and...
30 CFR 57.4101 - Warning signs.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Warning signs. 57.4101 Section 57.4101 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Prohibitions/precautions/housekeeping § 57.4101 Warning signs. Readily visible signs prohibiting smoking and...
30 CFR 57.4101 - Warning signs.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Warning signs. 57.4101 Section 57.4101 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Prohibitions/precautions/housekeeping § 57.4101 Warning signs. Readily visible signs prohibiting smoking and...
30 CFR 56.4101 - Warning signs.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Warning signs. 56.4101 Section 56.4101 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Prohibitions/precautions/housekeeping § 56.4101 Warning signs. Readily visible signs prohibiting smoking and...
30 CFR 56.4101 - Warning signs.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Warning signs. 56.4101 Section 56.4101 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Prohibitions/precautions/housekeeping § 56.4101 Warning signs. Readily visible signs prohibiting smoking and...
30 CFR 57.4101 - Warning signs.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Warning signs. 57.4101 Section 57.4101 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Prohibitions/precautions/housekeeping § 57.4101 Warning signs. Readily visible signs prohibiting smoking and...
30 CFR 56.4101 - Warning signs.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Warning signs. 56.4101 Section 56.4101 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Prohibitions/precautions/housekeeping § 56.4101 Warning signs. Readily visible signs prohibiting smoking and...
Safety evaluation of intersection conflict warning system.
DOT National Transportation Integrated Search
2016-06-01
FHWA organized a pooled fund study of 40 States to evaluate low-cost safety strategies as part of its strategic highway safety effort. One of the strategies selected for evaluation was intersection conflict warning systems (ICWSs). This strategy is i...
The effects of compliance cost and specific consequence information on the use of safety equipment.
Hathaway, J A; Dingus, T A
1992-12-01
The effects of compliance cost and warning content on the use of protective eyewear by racquetball players were evaluated. Four-hundred-twenty subjects were observed for use of eye protection in a field setting. Results indicate that proximal placement of eyewear and the inclusion of specific consequence warning information increased safety equipment use. Implications of this research for augmenting warning effectiveness and safety are discussed.
30 CFR 75.1101-10 - Water sprinkler systems; fire warning devices at belt drives.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Water sprinkler systems; fire warning devices..., DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire Protection § 75.1101-10 Water sprinkler systems; fire warning devices at belt drives. Each water sprinkler...
30 CFR 75.1101-10 - Water sprinkler systems; fire warning devices at belt drives.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Water sprinkler systems; fire warning devices..., DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire Protection § 75.1101-10 Water sprinkler systems; fire warning devices at belt drives. Each water sprinkler...
30 CFR 75.1101-10 - Water sprinkler systems; fire warning devices at belt drives.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Water sprinkler systems; fire warning devices..., DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire Protection § 75.1101-10 Water sprinkler systems; fire warning devices at belt drives. Each water sprinkler...
30 CFR 75.1101-10 - Water sprinkler systems; fire warning devices at belt drives.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Water sprinkler systems; fire warning devices..., DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire Protection § 75.1101-10 Water sprinkler systems; fire warning devices at belt drives. Each water sprinkler...
30 CFR 75.1101-10 - Water sprinkler systems; fire warning devices at belt drives.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Water sprinkler systems; fire warning devices..., DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire Protection § 75.1101-10 Water sprinkler systems; fire warning devices at belt drives. Each water sprinkler...
Research on Early Warning of Chinese Food Safety Based on Social Physics
NASA Astrophysics Data System (ADS)
Ma, Yonghuan; Niu, Wenyuan; Li, Qianqian
Based on social physics, this paper designs the index system of food safety, builds early warning model of food safety, calculates the degree of food safety, and assesses the state of early warning of 2007 in China. The result shows the degree of food safety is near 0.7 in securer state, belonging to slight emergency. It is much lower in eastern areas of developed regions, belonging to insecure state in the mass. That the food safety is ensured in major grain producing areas, Inner Mongolia, Ningxia and Xinjiang is the prerequisite of realizing the food safety of China. The result also shows four significant indices, grain production capacity, grain circulation order, grain demand and grain supply, which are important indicatio to control food safety.
Warning Signs of Childhood Emergencies
... Health & Safety Tips » Warning Signs of Childhood Emergencies Warning Signs of Childhood Emergencies Because their bodies are ... if your child exhibits any of the following warning signs of a medical emergency: Any significant change ...
Recall of indoor tanning salon warnings and safety guidelines among a national sample of tanners.
Day, Ashley K; Coups, Elliot J; Manne, Sharon L; Stapleton, Jerod L
2016-12-01
Indoor tanning (IT) is a known carcinogen, and regulation has increased across the USA. However, there is minimal point-of-sale regulation for adult users. The purpose of the present study is to explore whether IT users recall being provided with warnings or safety guidelines at tanning salons. A national sample of 273 young adult, female IT users (mean age = 22.26, SD = 2.38) was surveyed regarding the frequency that they recalled being provided with six different warnings and safety guidelines when at tanning salons. Between 65 and 90.1 % of participants reported recalling the various warnings and guidelines. Having very fair skin was reported by 16.8 % of participants, and these high-risk individuals were less likely to recall having read and signed a consent form than other IT users (p = .002). The current level of regulation is insufficient to provide IT users with consistent warnings and safety guidelines at tanning salons.
30 CFR 57.19108 - Posting warning signs during shaft work.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Posting warning signs during shaft work. 57.19108 Section 57.19108 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL...
30 CFR 56.14208 - Warning devices.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Warning devices. 56.14208 Section 56.14208... Safety Practices and Operational Procedures § 56.14208 Warning devices. (a) Visible warning devices shall... feet beyond the rear of the equipment shall have a warning flag at the end of the projection. Under...
30 CFR 56.14208 - Warning devices.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Warning devices. 56.14208 Section 56.14208... Safety Practices and Operational Procedures § 56.14208 Warning devices. (a) Visible warning devices shall... feet beyond the rear of the equipment shall have a warning flag at the end of the projection. Under...
30 CFR 56.14208 - Warning devices.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Warning devices. 56.14208 Section 56.14208... Safety Practices and Operational Procedures § 56.14208 Warning devices. (a) Visible warning devices shall... feet beyond the rear of the equipment shall have a warning flag at the end of the projection. Under...
30 CFR 57.14208 - Warning devices.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Warning devices. 57.14208 Section 57.14208... Equipment Safety Practices and Operational Procedures § 57.14208 Warning devices. (a) Visible warning... four feet beyond the rear of the equipment shall have a warning flag at the end of the projection...
30 CFR 57.14208 - Warning devices.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Warning devices. 57.14208 Section 57.14208... Equipment Safety Practices and Operational Procedures § 57.14208 Warning devices. (a) Visible warning... four feet beyond the rear of the equipment shall have a warning flag at the end of the projection...
30 CFR 56.14208 - Warning devices.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Warning devices. 56.14208 Section 56.14208... Safety Practices and Operational Procedures § 56.14208 Warning devices. (a) Visible warning devices shall... feet beyond the rear of the equipment shall have a warning flag at the end of the projection. Under...
30 CFR 57.14208 - Warning devices.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Warning devices. 57.14208 Section 57.14208... Equipment Safety Practices and Operational Procedures § 57.14208 Warning devices. (a) Visible warning... four feet beyond the rear of the equipment shall have a warning flag at the end of the projection...
30 CFR 57.14208 - Warning devices.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Warning devices. 57.14208 Section 57.14208... Equipment Safety Practices and Operational Procedures § 57.14208 Warning devices. (a) Visible warning... four feet beyond the rear of the equipment shall have a warning flag at the end of the projection...
30 CFR 57.14208 - Warning devices.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Warning devices. 57.14208 Section 57.14208... Equipment Safety Practices and Operational Procedures § 57.14208 Warning devices. (a) Visible warning... four feet beyond the rear of the equipment shall have a warning flag at the end of the projection...
30 CFR 56.14208 - Warning devices.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Warning devices. 56.14208 Section 56.14208... Safety Practices and Operational Procedures § 56.14208 Warning devices. (a) Visible warning devices shall... feet beyond the rear of the equipment shall have a warning flag at the end of the projection. Under...
NASA Technical Reports Server (NTRS)
Wiener, Earl L.
1988-01-01
The aims and methods of aircraft cockpit automation are reviewed from a human-factors perspective. Consideration is given to the mixed pilot reception of increased automation, government concern with the safety and reliability of highly automated aircraft, the formal definition of automation, and the ground-proximity warning system and accidents involving controlled flight into terrain. The factors motivating automation include technology availability; safety; economy, reliability, and maintenance; workload reduction and two-pilot certification; more accurate maneuvering and navigation; display flexibility; economy of cockpit space; and military requirements.
Enhanced proximity warning system (EPWS) for locomotives
DOT National Transportation Integrated Search
1997-10-01
The primary focus of the Enhanced Proximity Warning System (EPWS) is to provide a cost effective means to improve safety of railroad operations, with the ability to implement on an incremental, building block approach. The main safety objective...
In-Vehicle Safety Advisory And Warning System (Ivsaws), Volume I: Executive Summary
DOT National Transportation Integrated Search
1996-03-01
THE INVEHICLE SAFETY ADVISORY AND WARNING SYSTEM (IVSAWS) IS A FEDERAL HIGHWAY ADMINISTRATION EFFORT TO DEVELOP A NATIONWIDE VEHICULAR INFORMATION SYSTEM THAT PROVIDES DRIVERS WITH ADVANCE, SUPPLEMENTAL NOTIFICATION OF DANGEROUS ROAD CONDITIONS USING...
Effectiveness of safety belt warning and interlock systems
DOT National Transportation Integrated Search
1973-04-01
Rental cars in Fayetteville, N.C., were equipped with four seat belt and warning systems: (Phase I) detachable shoulder and lap belt, no warning system; (Phase II) detachable shoulder and lap belt, warning system (January 1, 1972 standard); (Phase II...
33 CFR 150.622 - What are the warning sign requirements?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false What are the warning sign... SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: OPERATIONS Workplace Safety and Health Warning Signs § 150.622 What are the warning sign requirements? The construction and use of warning signs must be in...
33 CFR 150.622 - What are the warning sign requirements?
Code of Federal Regulations, 2012 CFR
2012-07-01
... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false What are the warning sign... SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: OPERATIONS Workplace Safety and Health Warning Signs § 150.622 What are the warning sign requirements? The construction and use of warning signs must be in...
30 CFR 56.14201 - Conveyor start-up warnings.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Conveyor start-up warnings. 56.14201 Section 56... Equipment Safety Practices and Operational Procedures § 56.14201 Conveyor start-up warnings. (a) When the... audible warning shall be installed and operated to warn persons that the conveyor will be started. Within...
33 CFR 150.622 - What are the warning sign requirements?
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false What are the warning sign... SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: OPERATIONS Workplace Safety and Health Warning Signs § 150.622 What are the warning sign requirements? The construction and use of warning signs must be in...
33 CFR 150.622 - What are the warning sign requirements?
Code of Federal Regulations, 2014 CFR
2014-07-01
... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false What are the warning sign... SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: OPERATIONS Workplace Safety and Health Warning Signs § 150.622 What are the warning sign requirements? The construction and use of warning signs must be in...
30 CFR 57.14201 - Conveyor start-up warnings.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Conveyor start-up warnings. 57.14201 Section 57... Equipment Safety Practices and Operational Procedures § 57.14201 Conveyor start-up warnings. (a) When the... audible warning shall be installed and operated to warn persons that the conveyor will be started. Within...
30 CFR 57.14201 - Conveyor start-up warnings.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Conveyor start-up warnings. 57.14201 Section 57... Equipment Safety Practices and Operational Procedures § 57.14201 Conveyor start-up warnings. (a) When the... audible warning shall be installed and operated to warn persons that the conveyor will be started. Within...
30 CFR 57.14201 - Conveyor start-up warnings.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Conveyor start-up warnings. 57.14201 Section 57... Equipment Safety Practices and Operational Procedures § 57.14201 Conveyor start-up warnings. (a) When the... audible warning shall be installed and operated to warn persons that the conveyor will be started. Within...
30 CFR 57.14201 - Conveyor start-up warnings.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Conveyor start-up warnings. 57.14201 Section 57... Equipment Safety Practices and Operational Procedures § 57.14201 Conveyor start-up warnings. (a) When the... audible warning shall be installed and operated to warn persons that the conveyor will be started. Within...
30 CFR 56.14201 - Conveyor start-up warnings.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Conveyor start-up warnings. 56.14201 Section 56... Equipment Safety Practices and Operational Procedures § 56.14201 Conveyor start-up warnings. (a) When the... audible warning shall be installed and operated to warn persons that the conveyor will be started. Within...
30 CFR 56.14201 - Conveyor start-up warnings.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Conveyor start-up warnings. 56.14201 Section 56... Equipment Safety Practices and Operational Procedures § 56.14201 Conveyor start-up warnings. (a) When the... audible warning shall be installed and operated to warn persons that the conveyor will be started. Within...
30 CFR 56.14201 - Conveyor start-up warnings.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Conveyor start-up warnings. 56.14201 Section 56... Equipment Safety Practices and Operational Procedures § 56.14201 Conveyor start-up warnings. (a) When the... audible warning shall be installed and operated to warn persons that the conveyor will be started. Within...
30 CFR 57.14201 - Conveyor start-up warnings.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Conveyor start-up warnings. 57.14201 Section 57... Equipment Safety Practices and Operational Procedures § 57.14201 Conveyor start-up warnings. (a) When the... audible warning shall be installed and operated to warn persons that the conveyor will be started. Within...
30 CFR 56.14201 - Conveyor start-up warnings.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Conveyor start-up warnings. 56.14201 Section 56... Equipment Safety Practices and Operational Procedures § 56.14201 Conveyor start-up warnings. (a) When the... audible warning shall be installed and operated to warn persons that the conveyor will be started. Within...
An analysis of legal warnings after drug approval in Thailand.
Sriphiromya, Pakawadee; Theeraroungchaisri, Anuchai
2015-02-01
Drug risk management has many tools for minimizing risk and black-boxed warnings (BBWs) are one of those tools. Some serious adverse drug reactions (ADRs) emerge only after a drug is marketed and used in a larger population. In Thailand, additional legal warnings after drug approval, in the form of black-boxed warnings, may be applied. Review of their characteristics can assist in the development of effective risk mitigation. This study was a cross sectional review of all legal warnings imposed in Thailand after drug approval (2003-2012). Any boxed warnings for biological products and revised warnings which were not related to safety were excluded. Nine legal warnings were evaluated. Seven related to drugs classes and two to individual drugs. The warnings involved four main types of predictable ADRs: drug-disease interactions, side effects, overdose and drug-drug interactions. The average time from first ADRs reported to legal warnings implementation was 12 years. The triggers were from both safety signals in Thailand and regulatory measures in other countries outside Thailand. Copyright © 2014 Elsevier Inc. All rights reserved.
Early identification systems for emerging foodborne hazards.
Marvin, H J P; Kleter, G A; Prandini, A; Dekkers, S; Bolton, D J
2009-05-01
This paper provides a non-exhausting overview of early warning systems for emerging foodborne hazards that are operating in the various places in the world. Special attention is given to endpoint-focussed early warning systems (i.e. ECDC, ISIS and GPHIN) and hazard-focussed early warning systems (i.e. FVO, RASFF and OIE) and their merit to successfully identify a food safety problem in an early stage is discussed. Besides these early warning systems which are based on monitoring of either disease symptoms or hazards, also early warning systems and/or activities that intend to predict the occurrence of a food safety hazard in its very beginning of development or before that are described. Examples are trend analysis, horizon scanning, early warning systems for mycotoxins in maize and/or wheat and information exchange networks (e.g. OIE and GIEWS). Furthermore, recent initiatives that aim to develop predictive early warning systems based on the holistic principle are discussed. The assumption of the researchers applying this principle is that developments outside the food production chain that are either directly or indirectly related to the development of a particular food safety hazard may also provide valuable information to predict the development of this hazard.
Early warning reporting categories analysis of recall and complaints data.
DOT National Transportation Integrated Search
2001-12-31
This analysis was performed to assist the National Highway Traffic Safety Administration (NHTSA) in identifying components and systems to be included in early warning reporting (EWR) categories that would be based upon historical safety-related recal...
Code of Federal Regulations, 2010 CFR
2010-04-01
... obesity, although their safety and effectiveness for that use have never been established. (b) Digitalis... the treatment of obesity. This use of digoxin or other digitalis glycosides is unwarranted. Moreover... the treatment of obesity is dangerous. (c) This section does not apply to digoxin products for oral...
Code of Federal Regulations, 2011 CFR
2011-04-01
... obesity, although their safety and effectiveness for that use have never been established. (b) Digitalis... the treatment of obesity. This use of digoxin or other digitalis glycosides is unwarranted. Moreover... the treatment of obesity is dangerous. (c) This section does not apply to digoxin products for oral...
Code of Federal Regulations, 2014 CFR
2014-04-01
... obesity, although their safety and effectiveness for that use have never been established. (b) Digitalis... the treatment of obesity. This use of digoxin or other digitalis glycosides is unwarranted. Moreover... the treatment of obesity is dangerous. (c) This section does not apply to digoxin products for oral...
Code of Federal Regulations, 2013 CFR
2013-04-01
... obesity, although their safety and effectiveness for that use have never been established. (b) Digitalis... the treatment of obesity. This use of digoxin or other digitalis glycosides is unwarranted. Moreover... the treatment of obesity is dangerous. (c) This section does not apply to digoxin products for oral...
Code of Federal Regulations, 2012 CFR
2012-04-01
... obesity, although their safety and effectiveness for that use have never been established. (b) Digitalis... the treatment of obesity. This use of digoxin or other digitalis glycosides is unwarranted. Moreover... the treatment of obesity is dangerous. (c) This section does not apply to digoxin products for oral...
Warnings and Human Response in the Oroville Dam Crisis, February 2017
NASA Astrophysics Data System (ADS)
Sorensen, J. H.; Mileti, D. S.; Needham, J. T.
2017-12-01
On February 7, 2017, erosion was detected in the primary spillway for Oroville Dam in northern California, causing an elevated concern for the safety of downstream communities. The situation seemed stable until heavy rains on February 11 resulted in the flow of water over the emergency spillway. On February 12, erosion below the emergency spillway was observed. At 4:21 PM on February 12, the Butte County Sheriff issued an evacuation order for "low levels of Oroville and downstream areas". Counties downstream followed with evacuation warnings. The purpose of this paper is to present preliminary results of research, conducted for the U.S. Army Corp of Engineers, on the Oroville event. This investigation is part of a research program designed to collect and analyze data on: 1) The timing of the decisions to order public evacuation warnings including the flow of information between engineers and geologist monitoring the hazard and local officials. 2) The method and timing of the dissemination of those warnings including the diffusion or warning by various communication channels. 3) The interpretation and response of the public to those warnings, including the timing of protective action decisions. The findings from these studies will be incorporated into risk assessment models used in assessing the impacts of dam and levee failures on a national basis.
33 CFR 127.1207 - Warning alarms.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Warning alarms. 127.1207 Section... Waterfront Facilities Handling Liquefied Hazardous Gas Equipment § 127.1207 Warning alarms. (a) Each marine... the local COTP additional or alternative warning devices that provide an equivalent level of safety...
33 CFR 127.1207 - Warning alarms.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Warning alarms. 127.1207 Section... Waterfront Facilities Handling Liquefied Hazardous Gas Equipment § 127.1207 Warning alarms. (a) Each marine... the local COTP additional or alternative warning devices that provide an equivalent level of safety...
33 CFR 127.1207 - Warning alarms.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Warning alarms. 127.1207 Section... Waterfront Facilities Handling Liquefied Hazardous Gas Equipment § 127.1207 Warning alarms. (a) Each marine... the local COTP additional or alternative warning devices that provide an equivalent level of safety...
33 CFR 127.1207 - Warning alarms.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Warning alarms. 127.1207 Section... Waterfront Facilities Handling Liquefied Hazardous Gas Equipment § 127.1207 Warning alarms. (a) Each marine... the local COTP additional or alternative warning devices that provide an equivalent level of safety...
33 CFR 127.1207 - Warning alarms.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Warning alarms. 127.1207 Section... Waterfront Facilities Handling Liquefied Hazardous Gas Equipment § 127.1207 Warning alarms. (a) Each marine... the local COTP additional or alternative warning devices that provide an equivalent level of safety...
DOT National Transportation Integrated Search
1998-10-01
This report presents the recommendations to improve the vehicle and equipment warning light policy for the Texas Department of Transportation, and improve the safety of the Department's pavement data collection activities. Research efforts include a ...
Safety impact of an integrated crash warning system based on field test data.
DOT National Transportation Integrated Search
2011-06-13
This paper provides the results of an analysis : conducted to assess the safety impact of an integrated : vehicle-based crash warning system based on : naturalistic driving data collected from a field : operational test. The system incorporates four ...
In-vehicle low-cost signing system
NASA Astrophysics Data System (ADS)
Greneker, Eugene F.
1997-02-01
There are approximately 20 million police radar detectors used on the highways of the United States daily. A highway hazard safety warning system has been developed by the Georgia Tech Research Institute, working under the sponsorship of the radar detector industry, to communicate highway safety alerts to the driver of any vehicle equipped with a police radar detector. In addition, the system causes the new generation of detectors that are already available to display a safety warning message on an alpha-numeric display. The Safety Warning SystemTM consists of a transmitter and a radar detector receiver or stand-alone safety warning receiver/display system. The transmitter can be mounted on police cars, emergency vehicles, utility vehicles, highly repair vehicles, and on stationary structures at fixed locations along the highway. The reception range of the transmitted signal is between 0.5 and 1.0 miles, depending on terrain. The system to be described may be one of the first applications of in-vehicle signing in the Intelligent Transportation System to be implemented, because the required infrastructure of receivers already exists.
30 CFR 57.14200 - Warnings prior to starting or moving equipment.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Warnings prior to starting or moving equipment... NONMETAL MINES Machinery and Equipment Safety Practices and Operational Procedures § 57.14200 Warnings... equipment, equipment operators shall sound a warning that is audible above the surrounding noise level or...
30 CFR 57.14200 - Warnings prior to starting or moving equipment.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Warnings prior to starting or moving equipment... NONMETAL MINES Machinery and Equipment Safety Practices and Operational Procedures § 57.14200 Warnings... equipment, equipment operators shall sound a warning that is audible above the surrounding noise level or...
30 CFR 75.208 - Warning devices.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Warning devices. 75.208 Section 75.208 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.208 Warning devices. Except during the installation of roof supports, the end of permanent roof support shall be posted with a readily visible warning...
30 CFR 75.208 - Warning devices.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Warning devices. 75.208 Section 75.208 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.208 Warning devices. Except during the installation of roof supports, the end of permanent roof support shall be posted with a readily visible warning...
30 CFR 56.20011 - Barricades and warning signs.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Barricades and warning signs. 56.20011 Section... § 56.20011 Barricades and warning signs. Areas where health or safety hazards exist that are not immediately obvious to employees shall be barricaded, or warning signs shall be posted at all approaches...
30 CFR 56.20011 - Barricades and warning signs.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Barricades and warning signs. 56.20011 Section... § 56.20011 Barricades and warning signs. Areas where health or safety hazards exist that are not immediately obvious to employees shall be barricaded, or warning signs shall be posted at all approaches...
30 CFR 56.20011 - Barricades and warning signs.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Barricades and warning signs. 56.20011 Section... § 56.20011 Barricades and warning signs. Areas where health or safety hazards exist that are not immediately obvious to employees shall be barricaded, or warning signs shall be posted at all approaches...
30 CFR 75.208 - Warning devices.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Warning devices. 75.208 Section 75.208 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.208 Warning devices. Except during the installation of roof supports, the end of permanent roof support shall be posted with a readily visible warning...
30 CFR 75.208 - Warning devices.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Warning devices. 75.208 Section 75.208 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.208 Warning devices. Except during the installation of roof supports, the end of permanent roof support shall be posted with a readily visible warning...
30 CFR 56.20011 - Barricades and warning signs.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Barricades and warning signs. 56.20011 Section... § 56.20011 Barricades and warning signs. Areas where health or safety hazards exist that are not immediately obvious to employees shall be barricaded, or warning signs shall be posted at all approaches...
30 CFR 56.20011 - Barricades and warning signs.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Barricades and warning signs. 56.20011 Section... § 56.20011 Barricades and warning signs. Areas where health or safety hazards exist that are not immediately obvious to employees shall be barricaded, or warning signs shall be posted at all approaches...
30 CFR 75.208 - Warning devices.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Warning devices. 75.208 Section 75.208 Mineral... SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.208 Warning devices. Except during the installation of roof supports, the end of permanent roof support shall be posted with a readily visible warning...
Advanced driver assistance systems: Using multimodal redundant warnings to enhance road safety.
Biondi, Francesco; Strayer, David L; Rossi, Riccardo; Gastaldi, Massimiliano; Mulatti, Claudio
2017-01-01
This study investigated whether multimodal redundant warnings presented by advanced assistance systems reduce brake response times. Warnings presented by assistance systems are designed to assist drivers by informing them that evasive driving maneuvers are needed in order to avoid a potential accident. If these warnings are poorly designed, they may distract drivers, slow their responses, and reduce road safety. In two experiments, participants drove a simulated vehicle equipped with a forward collision avoidance system. Auditory, vibrotactile, and multimodal warnings were presented when the time to collision was shorter than five seconds. The effects of these warnings were investigated with participants performing a concurrent cell phone conversation (Exp. 1) or driving in high-density traffic (Exp. 2). Braking times and subjective workload were measured. Multimodal redundant warnings elicited faster braking reaction times. These warnings were found to be effective even when talking on a cell phone (Exp. 1) or driving in dense traffic (Exp. 2). Multimodal warnings produced higher ratings of urgency, but ratings of frustration did not increase compared to other warnings. Findings obtained in these two experiments are important given that faster braking responses may reduce the potential for a collision. Copyright © 2016 Elsevier Ltd. All rights reserved.
Zhang, Nan; Huang, Hong; Su, Boni; Zhao, Jinlong; Zhang, Bo
2014-01-01
Knowing the information dissemination mechanisms of different media and having an efficient information dissemination plan for disaster pre-warning plays a very important role in reducing losses and ensuring the safety of human beings. In this paper we established models of information dissemination for six typical information media, including short message service (SMS), microblogs, news portals, cell phones, television, and oral communication. Then, the information dissemination capability of each medium concerning individuals of different ages, genders, and residential areas was simulated, and the dissemination characteristics were studied. Finally, radar graphs were used to illustrate comprehensive assessments of the six media; these graphs show directly the information dissemination characteristics of all media. The models and the results are essential for improving the efficiency of information dissemination for the purpose of disaster pre-warning and for formulating emergency plans which help to reduce the possibility of injuries, deaths and other losses in a disaster. PMID:24878739
Zhang, Nan; Huang, Hong; Su, Boni; Zhao, Jinlong; Zhang, Bo
2014-01-01
Knowing the information dissemination mechanisms of different media and having an efficient information dissemination plan for disaster pre-warning plays a very important role in reducing losses and ensuring the safety of human beings. In this paper we established models of information dissemination for six typical information media, including short message service (SMS), microblogs, news portals, cell phones, television, and oral communication. Then, the information dissemination capability of each medium concerning individuals of different ages, genders, and residential areas was simulated, and the dissemination characteristics were studied. Finally, radar graphs were used to illustrate comprehensive assessments of the six media; these graphs show directly the information dissemination characteristics of all media. The models and the results are essential for improving the efficiency of information dissemination for the purpose of disaster pre-warning and for formulating emergency plans which help to reduce the possibility of injuries, deaths and other losses in a disaster.
Nonyelum, Stanley Catherine; Nkem, Nwachukwu; Ifeyinwa, Chijoke-Nwauche; Orisakwe, Orish Ebere
2010-10-01
To investigate the adequacy of safety warnings and first aid instructions on the labels of pharmaceutical and consumer products in Nigeria. A market basket method (total collection of all available samples) was used to investigate the adequacy of safety warnings and first aid instructions on the labels of 600 pharmaceutical and consumer products in Nigeria. The results showed that 69.8% of the products had adequate warnings whereas 385 (64.1%) of the products screened had legible product warnings. Only 52 (8.7%) of the total number of products had appropriate first aid instructions while only 25 (4.12%) of the products described symptoms and full treatment of poisoning by the product and 319 (53.2%) products surveyed recommended calling a health professional. A total of 31 (5.2%) products had labels that were considered too technical (non English). Of the 600 products, 386 (64.3%) had dosage instructions that were considered adequate while 538 (89.6%) had adequate storage instructions. About 68% of the products had partially correct warnings while 44 or 7.3% had partially correct first aid instructions. Some products had neither warnings nor first aid instructions. This study suggests a not too impressive improvement in the correctness and appropriateness of label information.
Prototype Rail Crossing Violation Warning Application Project Report.
DOT National Transportation Integrated Search
2017-09-05
This report is the Project Report for the Rail Crossing Violation Warning (RCVW) safety application developed for the project on Rail Crossing Violation Warning Application and Infrastructure Connection, providing a means for equipped connected vehic...
Aviation safety and automation technology for subsonic transports
NASA Technical Reports Server (NTRS)
Albers, James A.
1991-01-01
Discussed here are aviation safety human factors and air traffic control (ATC) automation research conducted at the NASA Ames Research Center. Research results are given in the areas of flight deck and ATC automations, displays and warning systems, crew coordination, and crew fatigue and jet lag. Accident investigation and an incident reporting system that is used to guide the human factors research is discussed. A design philosophy for human-centered automation is given, along with an evaluation of automation on advanced technology transports. Intelligent error tolerant systems such as electronic checklists are discussed along with design guidelines for reducing procedure errors. The data on evaluation of Crew Resource Management (CRM) training indicates highly significant positive changes in appropriate flight deck behavior and more effective use of available resources for crew members receiving the training.
Connoted hazard and perceived importance of fluorescent, neon, and standard safety colors.
Zielinska, O A; Mayhorn, C B; Wogalter, M S
2017-11-01
The perceived hazard and rated importance of standard safety, fluorescent, and neon colors are investigated. Colors are used in warnings to enhance hazard communication. Red has consistently been rated as the highest in perceived hazard. Orange, yellow, and black are the next highest in connoted hazard; however, there is discrepancy in their ordering. Safety standards, such as ANSI Z535.1, also list colors to convey important information, but little research has examined the perceived importance of colors. In addition to standard safety colors, fluorescent colors are more commonly used in warnings. Understanding hazard and importance perceptions of standard safety and fluorescent colors is necessary to create effective warnings. Ninety participants rated and ranked a total of 33 colors on both perceived hazard and perceived importance. Rated highest were the safety red colors from the American National Standard Institute (ANSI), International Organization for Standardization (ISO), and Federal Highway Administration (FHWA) together with three fluorescent colors (orange, yellow, and yellow-green) from 3 M on both dimensions. Rankings were similar to ratings except that fluorescent orange was the highest on perceived hazard, while fluorescent orange and safety red from the ANSI were ranked as the highest in perceived importance. Fluorescent colors convey hazard and importance levels as high as the standard safety red colors. Implications for conveying hazard and importance in warnings through color are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Fakhruddin, S. H. M.; Babel, Mukand S.; Kawasaki, Akiyuki
2014-05-01
Coastal inundations are an increasing threat to the lives and livelihoods of people living in low-lying, highly-populated coastal areas. According to a World Bank Report in 2005, at least 2.6 million people may have drowned due to coastal inundation, particularly caused by storm surges, over the last 200 years. Forecasting and prediction of natural events, such as tropical and extra-tropical cyclones, inland flooding, and severe winter weather, provide critical guidance to emergency managers and decision-makers from the local to the national level, with the goal of minimizing both human and economic losses. This guidance is used to facilitate evacuation route planning, post-disaster response and resource deployment, and critical infrastructure protection and securing, and it must be available within a time window in which decision makers can take appropriate action. Recognizing this extreme vulnerability of coastal areas to inundation/flooding, and with a view to improve safety-related services for the community, research should strongly enhance today's forecasting, prediction and early warning capabilities in order to improve the assessment of coastal vulnerability and risks and develop adequate prevention, mitigation and preparedness measures. This paper tries to develop an impact-oriented quantitative coastal inundation forecasting and early warning system with social and economic assessment to address the challenges faced by coastal communities to enhance their safety and to support sustainable development, through the improvement of coastal inundation forecasting and warning systems.
Light vehicle forward-looking, rear-end collision warning system performance guidelines
DOT National Transportation Integrated Search
1998-05-01
This document presents performance guidelines for forward-looking, rear-end collision warning systems (abbreviated FCW) for improving vehicular safety by preventing or mitigating vehicular rear-end collisions through driver notification or warning. T...
CPSC Warns of Carbon Monoxide Poisoning with Camping Equipment
... Warns of Carbon Monoxide Poisoning Hazard with Camping Equipment The U.S. Consumer Product Safety Commission (CPSC) warns ... about the carbon monoxide (CO) hazard with camping equipment. CO can kill you! From 2002–2006, CPSC ...
30 CFR 56.14200 - Warnings prior to starting or moving equipment.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Warnings prior to starting or moving equipment... MINES Machinery and Equipment Safety Practices and Operational Procedures § 56.14200 Warnings prior to... operators shall sound a warning that is audible above the surrounding noise level or use other effective...
49 CFR 571.125 - Standard No. 125; Warning devices.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 6 2010-10-01 2010-10-01 false Standard No. 125; Warning devices. 571.125 Section... Motor Vehicle Safety Standards § 571.125 Standard No. 125; Warning devices. S1. Scope. This standard... affixed to both faces of the warning device. Alternatively, a dual purpose orange fluorescent and red...
30 CFR 56.14200 - Warnings prior to starting or moving equipment.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Warnings prior to starting or moving equipment... MINES Machinery and Equipment Safety Practices and Operational Procedures § 56.14200 Warnings prior to... operators shall sound a warning that is audible above the surrounding noise level or use other effective...
49 CFR 571.125 - Standard No. 125; Warning devices.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 6 2011-10-01 2011-10-01 false Standard No. 125; Warning devices. 571.125 Section... Motor Vehicle Safety Standards § 571.125 Standard No. 125; Warning devices. S1. Scope. This standard... affixed to both faces of the warning device. Alternatively, a dual purpose orange fluorescent and red...
30 CFR 77.1102 - Warning signs; smoking and open flame.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Warning signs; smoking and open flame. 77.1102 Section 77.1102 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE... COAL MINES Fire Protection § 77.1102 Warning signs; smoking and open flame. Signs warning against...
49 CFR 571.125 - Standard No. 125; Warning devices.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 6 2012-10-01 2012-10-01 false Standard No. 125; Warning devices. 571.125 Section... Motor Vehicle Safety Standards § 571.125 Standard No. 125; Warning devices. S1. Scope. This standard... affixed to both faces of the warning device. Alternatively, a dual purpose orange fluorescent and red...
30 CFR 57.20011 - Barricades and warning signs.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Barricades and warning signs. 57.20011 Section... Miscellaneous § 57.20011 Barricades and warning signs. Areas where health or safety hazards exist that are not immediately obvious to employees shall be barricaded, or warning signs shall be posted at all approaches...
49 CFR 571.125 - Standard No. 125; Warning devices.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 6 2013-10-01 2013-10-01 false Standard No. 125; Warning devices. 571.125 Section... Motor Vehicle Safety Standards § 571.125 Standard No. 125; Warning devices. S1. Scope. This standard... affixed to both faces of the warning device. Alternatively, a dual purpose orange fluorescent and red...
30 CFR 57.20011 - Barricades and warning signs.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Barricades and warning signs. 57.20011 Section... Miscellaneous § 57.20011 Barricades and warning signs. Areas where health or safety hazards exist that are not immediately obvious to employees shall be barricaded, or warning signs shall be posted at all approaches...
30 CFR 57.20011 - Barricades and warning signs.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Barricades and warning signs. 57.20011 Section... Miscellaneous § 57.20011 Barricades and warning signs. Areas where health or safety hazards exist that are not immediately obvious to employees shall be barricaded, or warning signs shall be posted at all approaches...
30 CFR 57.20011 - Barricades and warning signs.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Barricades and warning signs. 57.20011 Section... Miscellaneous § 57.20011 Barricades and warning signs. Areas where health or safety hazards exist that are not immediately obvious to employees shall be barricaded, or warning signs shall be posted at all approaches...
30 CFR 57.20011 - Barricades and warning signs.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Barricades and warning signs. 57.20011 Section... Miscellaneous § 57.20011 Barricades and warning signs. Areas where health or safety hazards exist that are not immediately obvious to employees shall be barricaded, or warning signs shall be posted at all approaches...
30 CFR 77.1102 - Warning signs; smoking and open flame.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Warning signs; smoking and open flame. 77.1102 Section 77.1102 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE... COAL MINES Fire Protection § 77.1102 Warning signs; smoking and open flame. Signs warning against...
30 CFR 56.14200 - Warnings prior to starting or moving equipment.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Warnings prior to starting or moving equipment... MINES Machinery and Equipment Safety Practices and Operational Procedures § 56.14200 Warnings prior to... operators shall sound a warning that is audible above the surrounding noise level or use other effective...
30 CFR 56.14200 - Warnings prior to starting or moving equipment.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Warnings prior to starting or moving equipment... MINES Machinery and Equipment Safety Practices and Operational Procedures § 56.14200 Warnings prior to... operators shall sound a warning that is audible above the surrounding noise level or use other effective...
49 CFR 571.125 - Standard No. 125; Warning devices.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 6 2014-10-01 2014-10-01 false Standard No. 125; Warning devices. 571.125 Section... Motor Vehicle Safety Standards § 571.125 Standard No. 125; Warning devices. S1. Scope. This standard... affixed to both faces of the warning device. Alternatively, a dual purpose orange fluorescent and red...
30 CFR 77.1102 - Warning signs; smoking and open flame.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Warning signs; smoking and open flame. 77.1102 Section 77.1102 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE... COAL MINES Fire Protection § 77.1102 Warning signs; smoking and open flame. Signs warning against...
Acquisition, extinction and temporal discrimination in human conditioned avoidance.
Molet, Mikaël; Leconte, Claire; Rosas, Juan M
2006-09-01
Two experiments were conducted with the aim of designing a videogame for the study of human conditioned avoidance. Participants had to destroy enemy spaceships with the goal of increasing the score in a counter. Coloured signals might announce the launching of a bomb that could hit participant's spaceship producing a 30 points decrease in participant's score. Three groups of participants were trained in discriminating between a warning signal (W) and a safety signal (S) in Experiment 1. Instrumental group could avoid the loss of points by hiding the spaceship before the offset of W. Participants in the Yoked group received the same treatment received by their instrumental partners, regardless of their behaviour. In the Pavlovian group, W was always followed by the loss of points, regardless of participant's behaviour. Discrimination between W and S was better in the Instrumental groups than in the Yoked and Pavlovian control groups. Experiment 2 found extinction of avoidance when the warning signal was not followed by the bomb. Temporal discrimination was found within the participants that received the instrumental contingency in both experiments, with higher avoidance response towards the end of the warning signal. Temporal discrimination disappeared after extinction in Experiment 2.
33 CFR 165.14-1414 - Safety Zones; Hawaiian Islands Commercial Harbors; HI.
Code of Federal Regulations, 2014 CFR
2014-07-01
... harbors, or all of these harbors, dependent upon details in the tsunami warning. These safety zones extend... period. Paragraph (b) of this section will be enforced when a tsunami warning has been issued for the... Coast Guard's Homeport Web site. Following the passage of the tsunami or tsunami threat and harbor...
30 CFR 75.1103-5 - Automatic fire warning devices; actions and response.
Code of Federal Regulations, 2012 CFR
2012-07-01
... hours after the belt is stopped, unless an examination for hot rollers and fire is made as prescribed in... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Automatic fire warning devices; actions and... OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire...
30 CFR 75.1103-5 - Automatic fire warning devices; actions and response.
Code of Federal Regulations, 2014 CFR
2014-07-01
... hours after the belt is stopped, unless an examination for hot rollers and fire is made as prescribed in... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Automatic fire warning devices; actions and... OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire...
Automated Safety Warning Controller (ASWC) Phase I - Proof of Concept
DOT National Transportation Integrated Search
2010-07-07
Automated warning systems are not a new concept within the transportation community. There are several projects on the state highway that use the concept of a roadway sensor initiating some type of motorist warning. To date, all of these systems are ...
Lane change warning threshold based on driver perception characteristics.
Wang, Chang; Sun, Qinyu; Fu, Rui; Li, Zhen; Zhang, Qiong
2018-08-01
Lane Change Warning system (LCW) is exploited to alleviate driver workload and improve the safety performance of lane changes. Depending on the secure threshold, the lane change warning system could transmit caution to drivers. Although the system possesses substantial benefits, it may perturb the conventional operating of the driver and affect driver judgment if the warning threshold does not conform to the driver perception of safety. Therefore, it is essential to establish an appropriate warning threshold to enhance the accuracy rate and acceptability of the lane change warning system. This research aims to identify the threshold that conforms to the driver perception of the ability to safely change lanes with a rear vehicle fast approaching. We propose a theoretical warning model of lane change based on a safe minimum distance and deceleration of the rear vehicle. For the purpose of acquiring the different safety levels of lane changes, 30 licensed drivers are recruited and we obtain the extreme moments represented by driver perception characteristics from a Front Extremity Test and a Rear Extremity Test implemented on the freeway. The required deceleration of the rear vehicle corresponding to the extreme time is calculated according to the proposed model. In light of discrepancies in the deceleration in these extremity experiments, we determine two levels of a hierarchical warning system. The purpose of the primary warning is to remind drivers of the existence of potentially dangerous vehicles and the second warning is used to warn the driver to stop changing lanes immediately. We use the signal detection theory to analyze the data. Ultimately, we confirm that the first deceleration threshold is 1.5 m/s 2 and the second deceleration threshold is 2.7 m/s 2 . The findings provide the basis for the algorithm design of LCW and enhance the acceptability of the intelligent system. Copyright © 2018 Elsevier Ltd. All rights reserved.
Putting Safety First in the Sky
NASA Technical Reports Server (NTRS)
2003-01-01
As a result of technology developed at NASA s Kennedy Space Center, pilots now have a hand-held personal safety device to warn them of potentially dangerous or deteriorating cabin pressure altitude conditions before hypoxia becomes a threat. The Personal Cabin Pressure Altitude Monitor and Warning System monitors cabin pressure to determine when supplemental oxygen should be used according to Federal Aviation Regulations. The device benefits both pressurized and nonpressurized aircraft operations - warning pressurized aircraft when the required safe cabin pressure altitude is compromised, and reminding nonpressurized aircraft when supplemental oxygen is needed.
Coastal Warning Display Program
! Boating Safety Beach Hazards Rip Currents Hypothermia Hurricanes Thunderstorms Lightning Coastal Flooding Tsunamis 406 EPIRB's National Weather Service Marine Forecasts COASTAL WARNING DISPLAY PROGRAM Marine COASTAL WARNING DISPLAY PROGRAM As of February 15, 1989, the National Weather Service retired its Coastal
DOT National Transportation Integrated Search
2010-10-01
The Volvo-Ford-UMTRI project: Safety Impact Methodology (SIM) for Lane Departure Warning is part of the U.S. Department of Transportation's Advanced Crash Avoidance Technologies (ACAT) program. The project developed a basic analytical framework for e...
NASA Astrophysics Data System (ADS)
Li, N.; Zhang, X. Y.; Zhou, X. T.; Leng, J.; Liang, Z.; Zheng, C.; Sun, X. F.
2008-03-01
Though the brief introduction of the completed structural health and safety monitoring warning systems for Shenzhen-Hongkong western corridor Shenzhen bay highway bridge (SZBHMS), the self-developed system frame, hardware and software scheme of this practical research project are systematically discussed in this paper. The data acquisition and transmission hardware and the basic software based on the NI (National Instruments) Company virtual instruments technology were selected in this system, which adopted GPS time service receiver technology and so on. The objectives are to establish the structural safety monitoring and status evaluation system to monitor the structural responses and working conditions in real time and to analyze the structural working statue using information obtained from the measured data. It will be also provided the scientific decision-making bases for the bridge management and maintenance. Potential technical approaches to the structural safety warning systems, status identification and evaluation method are presented. The result indicated that the performance of the system has achieved the desired objectives, ensure the longterm high reliability, real time concurrence and advanced technology of SZBHMS. The innovate achievement which is the first time to implement in domestic, provide the reference for long-span bridge structural health and safety monitoring warning systems design.
30 CFR 57.19108 - Posting warning signs during shaft work.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Posting warning signs during shaft work. 57.19108 Section 57.19108 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... MINES Personnel Hoisting Shafts § 57.19108 Posting warning signs during shaft work. When persons are...
30 CFR 57.19108 - Posting warning signs during shaft work.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Posting warning signs during shaft work. 57.19108 Section 57.19108 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... MINES Personnel Hoisting Shafts § 57.19108 Posting warning signs during shaft work. When persons are...
75 FR 51178 - Safety Standard for Infant Walkers; Correction
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-19
... provision concerning warning statements on walkers with parking brakes. DATES: Effective on December 21... the last sentence. Another provision, at Sec. 1216.2(b)(21)(i), concerning a warning statement for walkers with parking brakes omitted a phrase indicating that the warning is only required for walkers that...
Research on early-warning index of the spatial temperature field in concrete dams.
Yang, Guang; Gu, Chongshi; Bao, Tengfei; Cui, Zhenming; Kan, Kan
2016-01-01
Warning indicators of the dam body's temperature are required for the real-time monitoring of the service conditions of concrete dams to ensure safety and normal operations. Warnings theories are traditionally targeted at a single point which have limitations, and the scientific warning theories on global behavior of the temperature field are non-existent. In this paper, first, in 3D space, the behavior of temperature field has regional dissimilarity. Through the Ward spatial clustering method, the temperature field was divided into regions. Second, the degree of order and degree of disorder of the temperature monitoring points were defined by the probability method. Third, the weight values of monitoring points of each regions were explored via projection pursuit. Forth, a temperature entropy expression that can describe degree of order of the spatial temperature field in concrete dams was established. Fifth, the early-warning index of temperature entropy was set up according to the calculated sequential value of temperature entropy. Finally, project cases verified the feasibility of the proposed theories. The early-warning index of temperature entropy is conducive to the improvement of early-warning ability and safety management levels during the operation of high concrete dams.
30 CFR 56.19108 - Posting warning signs during shaft work.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Posting warning signs during shaft work. 56.19108 Section 56.19108 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... Personnel Hoisting Shafts § 56.19108 Posting warning signs during shaft work. When persons are working in a...
30 CFR 56.19108 - Posting warning signs during shaft work.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Posting warning signs during shaft work. 56.19108 Section 56.19108 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... Personnel Hoisting Shafts § 56.19108 Posting warning signs during shaft work. When persons are working in a...
30 CFR 56.19108 - Posting warning signs during shaft work.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Posting warning signs during shaft work. 56.19108 Section 56.19108 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... Personnel Hoisting Shafts § 56.19108 Posting warning signs during shaft work. When persons are working in a...
30 CFR 56.19108 - Posting warning signs during shaft work.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Posting warning signs during shaft work. 56.19108 Section 56.19108 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... Personnel Hoisting Shafts § 56.19108 Posting warning signs during shaft work. When persons are working in a...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-26
... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration 49 CFR Parts 573, 577, and 579 [Docket No. NHTSA--2012-0068; Notice 3] RIN 2127-AK72 Early Warning Reporting, Foreign Defect... final rule. Id. Manufacturers with early warning reporting (EWR) accounts may obtain a copy of the VIN...
Work vehicle warning lights : color options and effectiveness.
DOT National Transportation Integrated Search
2015-09-01
KTC reviewed existing regulations, guidance, and practices to assess the Kentucky Transportation Cabinets warning : lights program on highway work vehicles. The Kentucky Revised Statutes categorizes KYTC vehicles as public safety : vehicles ...
Halloran, Kylene; Barash, Paul G
2010-06-01
To evaluate the United States Food and Drug Administration use of the black-box warning system to promote drug safety and to examine the droperidol black-box warning as a case study. Scientific studies report that there is no basis to issue a black-box warning for perioperative administration of droperidol for postoperative nausea and vomiting on the basis of the potential of adverse cardiac events (prolongation of the QT interval and/or development of torsades de pointes). Rather than relying on well conducted clinical investigations, the Food and Drug Administration subjectively issued a black-box warning to droperidol, which effectively removed droperidol from clinical practice for the indication of postoperative nausea and vomiting. Newer data suggest that the incidence of prolongation of the QT interval and the occurrence of torsades de pointes is similar to more expensive alternative medications used to treat postoperative nausea and vomiting.
NASA Technical Reports Server (NTRS)
Ray, Paul S.
1992-01-01
The safety and survival of the crewmembers has been the prime concern of NASA. Previous studies have been conducted mainly for emergencies occurring during the operating mode of the fully assembled Station. The present study was conducted to evaluate the emergency requirements for the caution and warning, logistics, maintenance, and assembly stage MB-6 of the Station in space. Effective caution and warning is essential to achieve safe egress in emergencies. In order to survive a long period in space, the safety and emergency requirements for maintenance, logistics, and extravehicular assembly operation in space must be met.
30 CFR 75.1103-3 - Automatic fire sensor and warning device systems; minimum requirements; general.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Automatic fire sensor and warning device systems; minimum requirements; general. 75.1103-3 Section 75.1103-3 Mineral Resources MINE SAFETY AND...-UNDERGROUND COAL MINES Fire Protection § 75.1103-3 Automatic fire sensor and warning device systems; minimum...
Hostenkamp, Gisela; Fischer, Katharina Elisabeth; Borch-Johnsen, Knut
2016-12-01
To analyse the impact of drug safety warnings from the European Medicines Agency (EMA) on drug utilisation and their interaction with information released through national reimbursement bodies. Insurance claims data on anti-diabetic drug prescriptions in primary care in Germany and Denmark were analysed using interrupted time series analysis, with EMA drug warnings for thiazolidinediones (TZDs) in 2007 and 2011 as the intervention. Monthly drug utilisation data per substance in defined daily dosages (DDD) consumed per 1000 insurees were retrieved from the Danish national drug prescriptions register and one large statutory sickness fund in Germany. TZDs were generally reimbursed in Germany but restricted to individual reimbursement in Denmark. Consequently, utilisation of TZDs was much higher in Germany in 2007 compared with Denmark. For rosiglitazone, the drug warning had a significant impact on utilisation, reducing the number of DDD per 1000 insurees per day by -0.0105 in Denmark and -0.0312 in Germany (p-values<0.05). For pioglitazone, neither of the drug warnings had a significant effect on utilisation. The impact of EMA drug warnings differed across countries and might be mediated by information released through national reimbursement bodies and physician associations. Increasing complexity of new drugs and modified approval procedures require a strengthening of information exchange between drug regulation bodies and physicians to ensure patient safety. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Lai, Yeong-Lin; Chou, Yung-Hua; Chang, Li-Chih
2018-01-01
Collisions between emergency vehicles for emergency medical services (EMS) and public road users have been a serious problem, impacting on the safety of road users, emergency medical technicians (EMTs), and the patients on board. The aim of this study is to develop a novel intelligent emergency vehicle warning system for EMS applications. The intelligent emergency vehicle warning system is developed by Internet of Things (IoT), radio-frequency identification (RFID), and Wi-Fi technologies. The system consists of three major parts: a system trigger tag, an RFID system in an emergency vehicle, and an RFID system at an intersection. The RFID system either in an emergency vehicle or at an intersection contains a controller, an ultrahigh-frequency (UHF) RFID reader module, a Wi-Fi module, and a 2.4-GHz antenna. In addition, a UHF ID antenna is especially designed for the RFID system in an emergency vehicle. The IoT system provides real-time visual warning at an intersection and siren warning from an emergency vehicle in order to effectively inform road users about an emergency vehicle approaching. The developed intelligent IoT emergency vehicle warning system demonstrates the capabilities of real-time visual and siren warnings for EMS safety.
The design of the light-flash warning light
NASA Astrophysics Data System (ADS)
Wang, Junli
2018-05-01
In today's society, the warning light has been used widely in people's daily life and various industries and agricultures. It is important to protect people's life and security. Light-flashing warning light is a kind of warning light control equipment which can control warning light automatically open and work in the state of blinking after dark, and it can automatically shut down after the dawn. It can achieve the flashing light automatic control and dual function. At present, light-flashing warning lights are mainly used in the projects of municipal construction. It is helpful to warn people and vehicles that passed in the construction site and ensure personal safety through using light-flashing warning light. Its design is simple, its performance is stable and it is also very convince to use it.
Evaluation of NDOR's actuated advance warning systems.
DOT National Transportation Integrated Search
2011-12-01
"Driver behavior within the dilemma zone can be a major safety concern at high-speed signalized intersections. The : Nebraska Department of Roads (NDOR) has developed and implemented an actuated advance warning (AAW) dilemma : zone protection system....
NASA Astrophysics Data System (ADS)
Khanam, Mosammat Samia; Biswas, Debasish; Rashid, Mohsina; Salam, Md Abdus
2017-12-01
Safety is one of the most important factors in the field of aviation. Though, modern aircraft are equipped with many instruments/devices to enhance the flight safety but it is seen that accidents/incidents are never reduced to zero. Analysis of the statistical summary of Commercial Jet Airplane accidents highlights that fatal accidents that occurred worldwide from 2006 through 2015 is 11% during taxing, loading/unloading, parking and towing. Human, handling the aircrafts is one of the most important links in aircraft maintenance and hence play a significant role in aviation safety. Effort has been made in this paper to obviate human error in aviation and outline an affordable system that monitors the uneven surface &obstacles for safe "towing in" and "towing out" of an aircraft by the ground crew. The system revolves around implementation of sonar technology by microcontroller. Ultrasonic sensors can be installed on aircraft wings and tail section to identify the uneven surface &obstacles ahead and provide early warning to the maintenance ground crews.
Design of vehicle intelligent anti-collision warning system
NASA Astrophysics Data System (ADS)
Xu, Yangyang; Wang, Ying
2018-05-01
This paper mainly designs a low cost, high-accuracy, micro-miniaturization, and digital display and acousto-optic alarm features of the vehicle intelligent anti-collision warning system that based on MCU AT89C51. The vehicle intelligent anti-collision warning system includes forward anti-collision warning system, auto parking systems and reversing anti-collision radar system. It mainly develops on the basis of ultrasonic distance measurement, its performance is reliable, thus the driving safety is greatly improved and the parking security and efficiency enhance enormously.
47 CFR 80.1109 - Distress, urgency, and safety communications.
Code of Federal Regulations, 2010 CFR
2010-10-01
... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS... communications include: navigational and meteorological warnings and urgent information; ship-to-ship safety...
47 CFR 80.1109 - Distress, urgency, and safety communications.
Code of Federal Regulations, 2014 CFR
2014-10-01
... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS... communications include: navigational and meteorological warnings and urgent information; ship-to-ship safety...
47 CFR 80.1109 - Distress, urgency, and safety communications.
Code of Federal Regulations, 2012 CFR
2012-10-01
... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS... communications include: navigational and meteorological warnings and urgent information; ship-to-ship safety...
47 CFR 80.1109 - Distress, urgency, and safety communications.
Code of Federal Regulations, 2013 CFR
2013-10-01
... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS... communications include: navigational and meteorological warnings and urgent information; ship-to-ship safety...
47 CFR 80.1109 - Distress, urgency, and safety communications.
Code of Federal Regulations, 2011 CFR
2011-10-01
... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS... communications include: navigational and meteorological warnings and urgent information; ship-to-ship safety...
Brake reactions of distracted drivers to pedestrian Forward Collision Warning systems.
Lubbe, Nils
2017-06-01
Forward Collision Warning (FCW) can be effective in directing driver attention towards a conflict and thereby aid in preventing or mitigating collisions. FCW systems aiming at pedestrian protection have been introduced onto the market, yet an assessment of their safety benefits depends on the accurate modeling of driver reactions when the system is activated. This study contributes by quantifying brake reaction time and brake behavior (deceleration levels and jerk) to compare the effectiveness of an audio-visual warning only, an added haptic brake pulse warning, and an added Head-Up Display in reducing the frequency of collisions with pedestrians. Further, this study provides a detailed data set suited for the design of assessment methods for car-to-pedestrian FCW systems. Brake response characteristics were measured for heavily distracted drivers who were subjected to a single FCW event in a high-fidelity driving simulator. The drivers maintained a self-regulated speed of 30km/h in an urban area, with gaze direction diverted from the forward roadway by a secondary task. Collision rates and brake reaction times differed significantly across FCW settings. Brake pulse warnings resulted in the lowest number of collisions and the shortest brake reaction times (mean 0.8s, SD 0.29s). Brake jerk and deceleration were independent of warning type. Ninety percent of drivers exceeded a maximum deceleration of 3.6m/s 2 and a jerk of 5.3m/s 3 . Brake pulse warning was the most effective FCW interface for preventing collisions. In addition, this study presents the data required for driver modeling for car-to-pedestrian FCW similar to Euro NCAP's 2015 car-to-car FCW assessment. Practical applications: Vehicle manufacturers should consider the introduction of brake pulse warnings to their FCW systems. Euro NCAP could introduce an assessment that quantifies the safety benefits of pedestrian FCW systems and thereby aid the proliferation of effective systems. Copyright © 2017 National Safety Council and Elsevier Ltd. All rights reserved.
Fagan, Pebbles; Pokhrel, Pallav; Herzog, Thaddeus A; Guy, Mignonne C; Sakuma, Kari-Lyn K; Trinidad, Dennis R; Cassel, Kevin; Jorgensen, Dorothy; Lynch, Tania; Felicitas-Perkins, Jamie Q; Palafox, Sherilyn; Hamamura, Faith; Maloney, Sarah; Degree, Kaylah; Sterling, Kymberle; Moolchan, Eric; Clanton, Mark S; Eissenberg, Thomas
2017-05-18
Prior to the Food and Drug Administration's (FDA) regulation of electronic cigarettes and warning statements related to nicotine addiction, there was no critical examination of manufacturer/distributor voluntary practices that could potentially inform FDA actions aimed to protect consumers. This study examined the content of warning statements and safety characteristics of electronic cigarette liquid bottles using a national sample. Research staff randomly selected four electronic cigarette liquid manufacturers/distributors from four U.S. geographic regions. Staff documented the characteristics of product packaging and content of warning statements on 147 electronic cigarette liquids (0-30 mg/ml of nicotine) purchased online from 16 manufacturers/distributors in April of 2016. Data showed that 97.9% of the electronic cigarette liquid bottles included a warning statement, most of which focused on nicotine exposure rather than health. Only 22.4% of bottles used a warning statement that indicated the product "contained nicotine". Of bottles that advertised a nicotine-based concentration of 12 mg/ml, 26% had a warning statements stated that the product "contains nicotine". None of the statements that indicated that the product "contained nicotine" stated that nicotine was "addictive". All bottles had a safety cap and 12% were in plastic shrink-wrap. Fifty-six percent of the websites had a minimum age requirement barrier that prevented under-aged persons from entering. Most manufacturers/distributors printed a warning statement on electronic cigarette liquid bottles, but avoided warning consumers about the presence and the addictiveness of nicotine. Studies are needed to examine manufacturer/distributor modifications to product packaging and how packaging affects consumer behaviors. These data can inform future FDA requirements related to the packaging and advertising of e-cigarette liquids; regulation related to the content of warning statements, including exposure warning statements, which are not currently mandated; and requirements on websites or language on packaging to help manufacturers adhere to the minimum age of purchase regulation. The data can also be used to help FDA develop additional guidance on the framing of statements on packaging that helps consumers make informed decisions about purchasing the product or protecting young people from use or unintentional exposure to the product. © The Author 2017. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
76 FR 22019 - Safety Standard for Toddler Beds
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-20
... warnings should increase consumers' understanding of the connection between the relevant behaviors and... CONSUMER PRODUCT SAFETY COMMISSION 16 CFR Part 1217 RIN 3041-AC79 Safety Standard for Toddler Beds AGENCY: Consumer Product Safety Commission. ACTION: Final rule. SUMMARY: The Consumer Product Safety...
A Detection Device for the Signs of Human Life in Accident
NASA Astrophysics Data System (ADS)
Ning, Li; Ruilan, Zhang; Jian, Liu; Ruirui, Cheng; Yuhong, Diao
2017-12-01
A detection device for the signs of human life in accidents is a device used in emergency situations, such as the crash site. the scene of natural disasters, the battlefield ruins. it designed to detect the life signs of the distress under the injured ambulance vital signs devices. The device can on human vital signs, including pulse, respiration physiological signals to make rapid and accurate response. After some calculations, and after contrast to normal human physiological parameters given warning signals, in order for them to make timely ambulance judgment. In this case the device is required to do gymnastics convenience, ease of movement, power and detection of small flexible easy realization. This device has the maximum protection of the wounded safety significance.
RESEARCH ON ENVIRONMENTAL HEALTH INTERVENTIONS: ETHICAL PROBLEMS AND SOLUTIONS
RESNIK, DAVID B.; ZELDIN, DARRYL C.; SHARP, RICHARD R.
2014-01-01
This article reviews a variety of ethical issues one must consider when conducting research on environmental health interventions on human subjects. The paper uses the Kennedy Krieger Institute lead abatement study as well as a hypothetical asthma study to discuss questions concerning benefits and risks, risk minimization, safety monitoring, the duty to warn, the duty to report, the use of control groups, informed consent, equitable subject selection, privacy, conflicts of interest, and community consultation. Research on environmental health interventions can make an important contribution to our understanding of human health and disease prevention, provided it is conducted in a manner that meets prevailing scientific, ethical, and legal standards for research on human subjects. PMID:16220621
Early Warning: Development of Confidential Incident Reporting Systems
NASA Technical Reports Server (NTRS)
OLeary, Mike J.; Chappell, Sheryl L.; Connell, Linda (Technical Monitor)
1996-01-01
Accidents hardly ever happen without warning. The combination, or sequence, of failures and mistakes that cause an accident may indeed be unique but the individual failures and mistakes rarely are. In the USA in 1974 the crews on two different aircraft misunderstood the same aeronautical chart and descended towards their destination dangerously early towards a mountain. The first crew were in good weather conditions and could see the mountain and resolved their misinterpretation of the chart. The second crew six weeks later were not so lucky. In cloud they had no clues to point out their mistake nor the presence of the mountain. The resulting crash and the ensuing inquiry, which brought to light the previous incident, shocked the country but gave it the impetus to instigate a safety reporting system. This system eventually became the NASA's Aviation Safety Reporting System (ASRS). The programme collects incident reports from pilots, controllers, mechanics, cabin attendants and many others involved in aviation operations. By disseminating this safety information the ASRS has helped enormously to give US airlines and airspace the highest safety standards. Accident prevention is a goal sought by everyone in the aviation industry and establishing effective incident reporting programmes can go a long way toward achieving that goal. This article will describe the steps and issues required to establish an incident reporting system. The authors summarize the lessons learned from the ASRS, now in its twentieth year of operation and from the Confidential Human Factors Reporting (HER) Programme run by British Airways, an airline that is a recognized world leader in safety reporting and analysis. The differences between government and airline operation of confidential safety reporting systems will be addressed.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-12
...The Food and Drug Administration (FDA) is announcing the availability of a guidance for industry entitled ``Warnings and Precautions, Contraindications, and Boxed Warning Sections of Labeling for Human Prescription Drug and Biological Products--Content and Format.'' This guidance is intended to assist applicants and reviewers in drafting the ``Warnings and Precautions, Contraindications, and Boxed Warning'' sections of labeling for human prescription drug and biological products. The recommendations in this guidance will help ensure that the labeling is clear, useful, informative, and to the extent possible, consistent in content and format.
Effectiveness of various safety belt warning systems
DOT National Transportation Integrated Search
1976-07-01
This observation study among rental car customers was conducted at the Sky Harbor Airport, Phoenix, Arizona, during the period August 4 - December 12, 1975. Overall objectives were (1) to determine if the warning system now required on 1975 and 1976 ...
Vehicle-to-infrastructure rail crossing violation warning : concept of operations.
DOT National Transportation Integrated Search
2016-03-31
This Concept of Operations (ConOps) document describes the operational characteristics of a Vehicle-to-Infrastructure (V2I) Rail Crossing Violation Warning (RCVW) safety application. The development of this document was completed with an advisory tea...
47 CFR 80.329 - Safety signals and messages.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 47 Telecommunication 5 2013-10-01 2013-10-01 false Safety signals and messages. 80.329 Section 80... Safety Procedures § 80.329 Safety signals and messages. (a) The safety signal indicates that the station... warnings. (b) In radiotelegraphy, the safety signal consists of three repetitions of the group TTT, sent...
47 CFR 80.329 - Safety signals and messages.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 47 Telecommunication 5 2014-10-01 2014-10-01 false Safety signals and messages. 80.329 Section 80... Safety Procedures § 80.329 Safety signals and messages. (a) The safety signal indicates that the station... warnings. (b) In radiotelegraphy, the safety signal consists of three repetitions of the group TTT, sent...
47 CFR 80.329 - Safety signals and messages.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 47 Telecommunication 5 2012-10-01 2012-10-01 false Safety signals and messages. 80.329 Section 80... Safety Procedures § 80.329 Safety signals and messages. (a) The safety signal indicates that the station... warnings. (b) In radiotelegraphy, the safety signal consists of three repetitions of the group TTT, sent...
DOT National Transportation Integrated Search
2009-05-01
As a major ITS initiative, the Vehicle Infrastructure Integration (VII) program is to revolutionize : transportation by creating an enabling communication infrastructure that will open up a wide range of : safety applications. The road-condition warn...
Performance of advance warning systems in a coordinated system : final report.
DOT National Transportation Integrated Search
2016-09-01
The Advance Warning System (AWS), developed by the Nebraska Department of Roads (NDOR) has proven to be effective at improving traffic safety at isolated signalized intersections. However, the effectiveness of the system has not been analyzed at sign...
Human Milk Handling and Storage Practices Among Peer Milk-Sharing Mothers.
Reyes-Foster, Beatriz M; Carter, Shannon K; Hinojosa, Melanie Sberna
2017-02-01
Peer milk sharing, the noncommercial sharing of human milk from one parent or caretaker directly to another for the purposes of feeding a child, appears to be an increasing infant-feeding practice. Although the U.S. Food and Drug Administration has issued a warning against the practice, little is known about how people who share human milk handle and store milk and whether these practices are consistent with clinical safety protocols. Research aim: This study aimed to learn about the milk-handling practices of expressed human milk by milk-sharing donors and recipient caretakers. In this article, we explore the degree to which donors and recipients adhere to the Academy of Breastfeeding Medicine clinical recommendations for safe handling and storage. Online surveys were collected from 321 parents engaged in peer milk sharing. Univariate descriptive statistics were used to describe the safe handling and storage procedures for milk donors and recipients. A two-sample t-test was used to compare safety items common to each group. Multivariate ordinary least squares regression analysis was used to examine sociodemographic correlates of milk safety practices within the sample group. Findings indicate that respondents engaged in peer milk sharing report predominantly positive safety practices. Multivariate analysis did not reveal any relationship between safety practices and sociodemographic characteristics. The number of safe practices did not differ between donors and recipients. Parents and caretakers who participate in peer human milk sharing report engaging in practices that should reduce risk of bacterial contamination of expressed peer shared milk. More research on this particular population is recommended.
Does direct human eye contact function as a warning cue for domestic sheep (Ovis aries)?
Beausoleil, Ngaio J; Stafford, Kevin J; Mellor, David J
2006-08-01
Direct eye contact may function as a warning cue during interspecific interactions, and human staring has been shown to influence the behavior of many species. The authors used an arena test to assess whether human staring altered the behavior of domestic sheep (Ovis aries) compared with no human eye contact. Sheep glanced at the staring human's face more often in the first 2 min of the test, indicating that they perceived a difference between the human stimuli. Staring also elicited more locomotor activity and urination than averted gaze. However, there were no differences in fear-related behaviors, suggesting that a staring human did not represent a greater immediate threat than a nonwatching human. These results imply that human staring is a warning cue for domestic sheep, but no more. Without further reinforcement, sheep quickly habituated to the warning cue. ((c) 2006 APA, all rights reserved).
Smart Roadside System for Driver Assistance and Safety Warnings: Framework and Applications
Jang, Jeong Ah; Kim, Hyun Suk; Cho, Han Byeog
2011-01-01
The use of newly emerging sensor technologies in traditional roadway systems can provide real-time traffic services to drivers through Telematics and Intelligent Transport Systems (ITSs). This paper introduces a smart roadside system that utilizes various sensors for driver assistance and traffic safety warnings. This paper shows two road application models for a smart roadside system and sensors: a red-light violation warning system for signalized intersections, and a speed advisory system for highways. Evaluation results for the two services are then shown using a micro-simulation method. In the given real-time applications for drivers, the framework and certain algorithms produce a very efficient solution with respect to the roadway type features and sensor type use. PMID:22164025
DOT National Transportation Integrated Search
2016-05-01
Collisions in the work zone have always been a contributing factor to compromising safety on urban roadways. The National Highway Traffic Safety Administration (NHTSA) and the State Transportation Authorities have implemented many safety countermeasu...
Benchekroun, Tahar Hakim; Pierlot, Sandrine
2012-01-01
Our world of industry and technology has, over the years, has seen undeniable successes in terms of safety and reliability. But major catastrophes and dramatic accidents continue, even today, to cause major human and material losses and to threaten the environment with pollution on a massive scale. Could these disasters and these accidents have been foreseen and avoided? Would it have been possible to anticipate their occurrence by detecting signals of potential hazards? It is unsettling to notice, through retrospective analysis of such events, that warnings had been issued long before the catastrophe or accident took place. This raises several questions, which we will attempt to address in this paper. Why are whistleblowers often not listened to, threatened, or simply ignored? Why are their warnings viewed as "bad omens" instead of essential resources to ensure safety? Do whistleblowers stand idly by, or do they implement individual and collective strategies to make themselves heard? Which managerial and organizational conditions are conducive to developing empowerment in whistleblowers? Based on four case studies, we attempt to address these questions, and offer a first level of analysis and explanation by proposing and defining two new concepts: operative resilience and strategic resilience.
Experimental Design for Evaluating the Safety Benefits of Railroad Advance Warning Signs
DOT National Transportation Integrated Search
1979-04-01
The report presents the findings and conclusions of a study to develop an experimental design and analysis plan for field testing and evaluation of the accident reduction potential of a proposed new railroad grade crossing advance warning sign. Sever...
2013-01-01
Background In March, 2007, a black box warning was issued by the Food and Drug Administration (FDA) to use the lowest possible erythropoiesis-stimulating agents (ESA) doses for treatment of anemia associated with renal disease. The goal is to determine if a change in ESA use was observed following the warning among US dialysis patients. Methods ESA therapy was examined from September 2004 through August 2009 (thirty months before and after the FDA black box warning) among adult Medicare hemodialysis patients. An interrupted time series model assessed the impact of the warnings. Results The FDA black box warning did not appear to influence ESA prescribing among the overall dialysis population. However, significant declines in ESA therapy after the FDA warnings were observed for selected populations. Patients with a hematocrit ≥36% had a declining month-to-month trend before (−164 units/week, p = <0.0001) and after the warnings (−80 units/week, p = .001), and a large drop in ESA level immediately after the black box (−4,744 units/week, p = <.0001). Not-for-profit facilities had a declining month-to-month trend before the warnings (−90 units/week, p = .009) and a large drop in ESA dose immediately afterwards (−2,487 units/week, p = 0.015). In contrast, for-profit facilities did not have a significant change in ESA prescribing. Conclusions ESA therapy had been both profitable for providers and controversial regarding benefits for nearly two decades. The extent to which a FDA black box warning highlighting important safety concerns influenced use of ESA therapy among nephrologists and dialysis providers was unknown. Our study found no evidence of changes in ESA prescribing for the overall dialysis population resulting from a FDA black box warning. PMID:23927675
Hoang, Toan Minh; Hong, Hyung Gil; Vokhidov, Husan; Park, Kang Ryoung
2016-08-18
With the increasing need for road lane detection used in lane departure warning systems and autonomous vehicles, many studies have been conducted to turn road lane detection into a virtual assistant to improve driving safety and reduce car accidents. Most of the previous research approaches detect the central line of a road lane and not the accurate left and right boundaries of the lane. In addition, they do not discriminate between dashed and solid lanes when detecting the road lanes. However, this discrimination is necessary for the safety of autonomous vehicles and the safety of vehicles driven by human drivers. To overcome these problems, we propose a method for road lane detection that distinguishes between dashed and solid lanes. Experimental results with the Caltech open database showed that our method outperforms conventional methods.
Hoang, Toan Minh; Hong, Hyung Gil; Vokhidov, Husan; Park, Kang Ryoung
2016-01-01
With the increasing need for road lane detection used in lane departure warning systems and autonomous vehicles, many studies have been conducted to turn road lane detection into a virtual assistant to improve driving safety and reduce car accidents. Most of the previous research approaches detect the central line of a road lane and not the accurate left and right boundaries of the lane. In addition, they do not discriminate between dashed and solid lanes when detecting the road lanes. However, this discrimination is necessary for the safety of autonomous vehicles and the safety of vehicles driven by human drivers. To overcome these problems, we propose a method for road lane detection that distinguishes between dashed and solid lanes. Experimental results with the Caltech open database showed that our method outperforms conventional methods. PMID:27548176
NASA Astrophysics Data System (ADS)
Lee, T.; Lee, C.; Kim, H.
2016-12-01
Abstract Song-do international city was constructed by reclaiming land from the coastal waters of Yeonsu-gu, Incheon Metropolitan City, Republic of Korea. The □-shaped cyclic artificial water way has been considered for improving water quality, waterfront and internal drainage in Song-do international city. By improving water quality, various marine facilities, such as marina, artificial beach, marine terminal, and so on, will be set up around the artificial water way for the waterfront. Since the water stage of the artificial water way changes depending on water gates operations, it is necessary to develop an urban inundation warning model to evaluate safeties of the waterfront facilities and its passengers. By considering characteristics of urban watershed, we calculate discharge flowing into the water way using XP-SWMM model. As a result of estimating 100-year flood frequency, although there are slight differences in drainage sections, the maximum flood discharge occurs in 90-min rainfall duration. In order to consider impacts of tide and hydraulic structure, we establish Inland drainage plans through the analysis of unsteady flow using HEC-RAS. The urban inundation warning model is configured to issue a warning when the water plain elevation exceeds EL. 1.5m which is usually managed at EL. 1.0m. In this study, the design flood stage of artificial water way and urban inundation warning model are developed for Song-do international city, and therefore it is expected that a reliability of management and operation of the waterfront facilities is improved. Keywords : Artificial Water Way; Waterfront; Urban Inundation Warning Model. Acknowlegement This research was supported by a grant [MPSS-NH-2015-79] through the Disaster and Safety Management Institute funded by Ministry of Public Safety and Security of Korean government.
DOT National Transportation Integrated Search
1988-02-01
THIS EVALUATION OF THE VEHICLE RADAR SAFETY SYSTEMS? ANTI-COLLISION DEVICE (HEREAFTER VRSS) WAS UNDERTAKEN BY THE OPERATOR PERFORMANCE AND SAFETY ANALYSIS DIVISION OF THE TRANSPORTATION SYSTEMS CENTER AT THE REQUEST OF THE NATIONAL HIGHWAY TRAFFIC SA...
Validation of Essential Acoustic Parameters for Highly Urgent In-Vehicle Collision Warnings.
Lewis, Bridget A; Eisert, Jesse L; Baldwin, Carryl L
2018-03-01
Objective The aim of this study was to validate the importance of key acoustic criteria for use as in-vehicle forward collision warning (FCW) systems. Background Despite recent advances in vehicle safety, automobile crashes remain one of the leading causes of death. As automation allows for more control of noncritical functions by the vehicle, the potential for disengagement and distraction from the driving task also increases. It is, therefore, as important as ever that in-vehicle safety-critical interfaces are intuitive and unambiguous, promoting effective collision avoidance responses upon first exposure even under divided-attention conditions. Method The current study used a driving simulator to assess the effectiveness of two warnings, one that met all essential acoustic parameters, one that met only some essential parameters, and a no-warning control in the context of a lead vehicle-following task in conjunction with a cognitive distractor task and collision event. Results Participants receiving an FCW comprising five essential acoustic components had improved collision avoidance responses relative to a no-warning condition and an FCW missing essential elements on their first exposure. Responses to a consistently good warning (GMU Prime) improved with subsequent exposures, whereas continued exposure to the less optimal FCW (GMU Sub-Prime) resulted in poorer performance even relative to receiving no warning at all. Conclusions This study provides support for previous warning design studies and for the validity of five key acoustic parameters essential for the design of effective in-vehicle FCWs. Application Results from this study have implications for the design of auditory FCWs and in-vehicle display design.
Wan, Jingyan; Wu, Changxu; Zhang, Yiqi
2016-09-01
Under the connected vehicle environment, vehicles will be able to exchange traffic information with roadway infrastructure and other vehicles. With such information, collision warning systems (CWSs) will be able to warn drivers with potentially hazardous situations within or out of sight and reduce collision accidents. The lead time of warning messages is a crucial factor in determining the effectiveness of CWSs in the prevention of traffic accidents. Accordingly, it is necessary to understand the effects of lead time on driving behaviors and explore the optimal lead time in various collision scenarios. The present driving simulator experiment studied the effects of controlled lead time at 16 levels (predetermined time headway from the subject vehicle to the collision location when the warning message broadcasted to a driver) on driving behaviors in various collision scenarios. Maximum effectiveness of warning messages was achieved when the controlled lead time was within the range of 5s to 8s. Specifically, the controlled lead time ranging from 4s to 8s led to the optimal safety benefit; and the controlled lead time ranging from 5s to 8s led to more gradual braking and shorter reaction time. Furthermore, a trapezoidal distribution of warning effectiveness was found by building a statistic model using curve estimation considering lead time, lifetime driving experience, and driving speed. The results indicated that the controlled lead time significantly affected driver performance. The findings have implications for the design of collision warning systems. Copyright © 2016 Elsevier Ltd and National Safety Council. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang, Kejian, E-mail: kejian.wang.bio@gmail.com; Weng, Zuquan; Sun, Liya
Adverse drug reaction (ADR) is of great importance to both regulatory agencies and the pharmaceutical industry. Various techniques, such as quantitative structure–activity relationship (QSAR) and animal toxicology, are widely used to identify potential risks during the preclinical stage of drug development. Despite these efforts, drugs with safety liabilities can still pass through safety checkpoints and enter the market. This situation raises the concern that conventional chemical structure analysis and phenotypic screening are not sufficient to avoid all clinical adverse events. Genomic expression data following in vitro drug treatments characterize drug actions and thus have become widely used in drug repositioning. Inmore » the present study, we explored prediction of ADRs based on the drug-induced gene-expression profiles from cultured human cells in the Connectivity Map (CMap) database. The results showed that drugs inducing comparable ADRs generally lead to similar CMap expression profiles. Based on such ADR-gene expression association, we established prediction models for various ADRs, including severe myocardial and infectious events. Drugs with FDA boxed warnings of safety liability were effectively identified. We therefore suggest that drug-induced gene expression change, in combination with effective computational methods, may provide a new dimension of information to facilitate systematic drug safety evaluation. - Highlights: • Drugs causing common toxicity lead to similar in vitro gene expression changes. • We built a model to predict drug toxicity with drug-specific expression profiles. • Drugs with FDA black box warnings were effectively identified by our model. • In vitro assay can detect severe toxicity in the early stage of drug development.« less
30 CFR 56.4101 - Warning signs.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Fire Prevention and Control... open flames shall be posted where a fire or explosion hazard exists. ...
30 CFR 57.4101 - Warning signs.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire Prevention and Control... open flames shall be posted where a fire or explosion hazard exists. ...
Visual warning system for worker safety on roadside work-zones.
DOT National Transportation Integrated Search
2016-08-01
Growing traffic on US roadways and heavy construction machinery on road construction sites pose a critical safety : threat to construction workers. This report summarizes the design and development of a worker safety system using : Dedicated Short Ra...
Study on the early warning mechanism for the security of blast furnace hearths
NASA Astrophysics Data System (ADS)
Zhao, Hong-bo; Huo, Shou-feng; Cheng, Shu-sen
2013-04-01
The campaign life of blast furnace (BF) hearths has become the limiting factor for safety and high efficiency production of modern BFs. However, the early warning mechanism of hearth security has not been clear. In this article, based on heat transfer calculations, heat flux and erosion monitoring, the features of heat flux and erosion were analyzed and compared among different types of hearths. The primary detecting elements, mathematical models, evaluating standards, and warning methods were discussed. A novel early warning mechanism with the three-level quantificational standards was proposed for BF hearth security.
Thomas, Matthew A.; Mirus, Benjamin B.; Collins, Brian D.; Lu, Ning; Godt, Jonathan W.
2018-01-01
Rainfall-induced shallow landsliding is a persistent hazard to human life and property. Despite the observed connection between infiltration through the unsaturated zone and shallow landslide initiation, there is considerable uncertainty in how estimates of unsaturated soil-water retention properties affect slope stability assessment. This source of uncertainty is critical to evaluating the utility of physics-based hydrologic modeling as a tool for landslide early warning. We employ a numerical model of variably saturated groundwater flow parameterized with an ensemble of texture-, laboratory-, and field-based estimates of soil-water retention properties for an extensively monitored landslide-prone site in the San Francisco Bay Area, CA, USA. Simulations of soil-water content, pore-water pressure, and the resultant factor of safety show considerable variability across and within these different parameter estimation techniques. In particular, we demonstrate that with the same permeability structure imposed across all simulations, the variability in soil-water retention properties strongly influences predictions of positive pore-water pressure coincident with widespread shallow landsliding. We also find that the ensemble of soil-water retention properties imposes an order-of-magnitude and nearly two-fold variability in seasonal and event-scale landslide susceptibility, respectively. Despite the reduced factor of safety uncertainty during wet conditions, parameters that control the dry end of the soil-water retention function markedly impact the ability of a hydrologic model to capture soil-water content dynamics observed in the field. These results suggest that variability in soil-water retention properties should be considered for objective physics-based simulation of landslide early warning criteria.
Water Safety and Lead Regulation: Physicians' Community Health Responsibilities.
Jennings, Bruce; Duncan, Leslie Lyons
2017-10-01
This article reviews the regulation of lead in drinking water, highlighting its epidemiological, engineering, and ethical aspects with a focus on the Flint water crisis. We first discuss water quality policy and its implementation with a focus on lead contamination of water, primarily from pipe systems between a water treatment facility and a tap. We then discuss physicians' roles and ethical responsibilities regarding safe drinking water using a human rights framework. We argue that physicians can play an important role in safeguarding drinking water in their communities by being vigilant, honoring the community's trust in them, and warning, educating, and empowering patients and broader communities so as to protect tap water safety and public health. © 2017 American Medical Association. All Rights Reserved.
Civilian helicopter accidents into water: analysis of 46 cases, 1979-2006.
Brooks, Christopher James; MacDonald, Conor Vaughan; Donati, Leo; Taber, Michael John
2008-10-01
When a helicopter crashes or ditches into water the crew and passengers must often make an escape from underwater and a number of the occupants do not survive. This paper examined fatality rates, human factors problems with escape, and causes of death in Canadian civilian registered helicopter accidents in water (1979-2006). Data obtained from the Transportation Safety Board of Canada was reviewed. Key issues such as fatalities, injuries, warning time, sinking, and inversion were examined. There were 46 helicopters that ditched into water. There were 124 crew and passengers involved. Of those, 27 (23%) crew and passengers died. Lack of warning time (55%), rapid sinking (72%), and inversion (35%) were the most common issues in the accidents. Survival rates for Canadian registered helicopter accidents into water (78%) show little change from previously reported worldwide data. Lack of warning time, rapid sinking, and inversion were the significant factors in the survival rate. The practical implication is that crew and passengers involved in planned flights over water must wear all the life support equipment on strap-in and not have it stowed on the back of the seat or in the cabin.
Incorporation of EGPWS in the NASA Ames Research Center 747-400 Flight Simulator
NASA Technical Reports Server (NTRS)
Sallant, Ghislain; DeGennaro, Robert A.
2001-01-01
The NASA Ames Research Center CAE Boeing 747300 flight simulator is used primarily for the study of human factors in aviation safety. The simulator is constantly upgraded to maintain a configuration match to a specific United Airlines aircraft and maintains the highest level of FAA certification to ensure credibility to the results of research programs. United's 747-400 fleet and hence the simulator are transitioning from the older Ground Proximity Warning System (GPWS) to the state-of-the-art Enhanced Ground Proximity Warning System (EGPWS). GPWS was an early attempt to reduce or eliminate Controlled Flight Into Terrain (CFIT). Basic GPWS alerting modes include: excessive descent rate, excessive terrain closure rate, altitude loss after takeoff, unsafe terrain clearance, excessive deviation below glideslope, advisory callouts and windshear alerting. However, since GPWS uses the radar altimeter which looks straight down, ample warning is not always provided. EGPWS retains all of the basic functions of GPWS but adds the ability to look ahead by comparing the aircraft position to an internal database and provide additional alerting and display capabilities. This paper evaluates three methods of incorporating EGPWS in the simulator and describes the implementation and architecture of the preferred option.
47 CFR 80.1133 - Transmission of safety communications.
Code of Federal Regulations, 2013 CFR
2013-10-01
... SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Operating... calling station has an important navigational or meteorological warning to transmit. (e) In radiotelephony...
47 CFR 80.1133 - Transmission of safety communications.
Code of Federal Regulations, 2011 CFR
2011-10-01
... SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Operating... calling station has an important navigational or meteorological warning to transmit. (e) In radiotelephony...
47 CFR 80.1133 - Transmission of safety communications.
Code of Federal Regulations, 2012 CFR
2012-10-01
... SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Operating... calling station has an important navigational or meteorological warning to transmit. (e) In radiotelephony...
47 CFR 80.1133 - Transmission of safety communications.
Code of Federal Regulations, 2014 CFR
2014-10-01
... SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Operating... calling station has an important navigational or meteorological warning to transmit. (e) In radiotelephony...
29 CFR 1915.2 - Scope and application.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS FOR SHIPYARD EMPLOYMENT General Provisions § 1915.2... States Coast Guard with respect to lights, warning devices, safety equipment and other matters relating...
29 CFR 1915.2 - Scope and application.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS FOR SHIPYARD EMPLOYMENT General Provisions § 1915.2... States Coast Guard with respect to lights, warning devices, safety equipment and other matters relating...
Some human factors issues in the development and evaluation of cockpit alerting and warning systems
NASA Technical Reports Server (NTRS)
Randle, R. J., Jr.; Larsen, W. E.; Williams, D. H.
1980-01-01
A set of general guidelines for evaluating a newly developed cockpit alerting and warning system in terms of human factors issues are provided. Although the discussion centers around a general methodology, it is made specifically to the issues involved in alerting systems. An overall statement of the current operational problem is presented. Human factors problems with reference to existing alerting and warning systems are described. The methodology for proceeding through system development to system test is discussed. The differences between traditional human factors laboratory evaluations and those required for evaluation of complex man-machine systems under development are emphasized. Performance evaluation in the alerting and warning subsystem using a hypothetical sample system is explained.
Revised text for TxDOT manual procedures for establishing speed zones, chapter 5, section 2.
DOT National Transportation Integrated Search
2010-02-01
Warning signs are intended to improve curve safety by alerting the driver to a change in : geometry that may not be apparent or expected. These signs notify drivers of the change : through the use of one or more of the curve warning signs identified ...
49 CFR 213.347 - Automotive or railroad crossings at grade.
Code of Federal Regulations, 2010 CFR
2010-10-01
... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRACK SAFETY STANDARDS Train Operations at Track Classes 6 and.../barrier system to address the protection of highway traffic and high speed trains. Trains shall not...-approved warning/barrier system exists on that track segment; and (2) All elements of that warning/barrier...
9 CFR 307.7 - Safety requirements for electrical stimulating (EST) equipment.
Code of Federal Regulations, 2011 CFR
2011-01-01
... beam sensors form the enclosure, the stimulating equipment shall be automatically shut off when the sensor signals are broken. (3) Mandatory Warning Devices and Signals. The following warning devices or.... (ii) An ANSI Z53.1-Color Code sign reading (a) “Danger Electrical Hazard” for stimulating voltage...
9 CFR 307.7 - Safety requirements for electrical stimulating (EST) equipment.
Code of Federal Regulations, 2010 CFR
2010-01-01
... beam sensors form the enclosure, the stimulating equipment shall be automatically shut off when the sensor signals are broken. (3) Mandatory Warning Devices and Signals. The following warning devices or.... (ii) An ANSI Z53.1-Color Code sign reading (a) “Danger Electrical Hazard” for stimulating voltage...
SU-E-T-599: Patient Safety Enhancements Through a Study of R&V System Override Data
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hendrickson, K; Vimolchalao, S
2015-06-15
Purpose: Record and verify (R&V) software systems include safety checks that compare actual machine parameters with prescribed values for a patient’s treatment, such as treatment couch position, linac, energy, and MUs. The therapist is warned of a mismatch with a pop-up and prompted to approve an override in order to continue without changes. Override approval is often legitimate, but the pop-up can also genuinely indicate a problem that would Result in the wrong treatment. When there are numerous pop-up warnings, human nature leads us to approve any override without careful reading, undermining the effectiveness of the safety mechanism. Methods: Overridemore » data was collected from our R&V system for all patients treated between October 8 and 29, 2012, on four linacs and entered into a spreadsheet. Additional data collected included treatment technique, disease site, immobilization, time, linac, and whether localization images were obtained. Data were analyzed using spreadsheet tools to reveal trends, patterns and associations that might suggest appropriate process changes that could decrease the total number of overrides. Results: 76 out of 113 patients had overrides. Out of the 944 treatments, 599 override items were generated. The majority were due to couch positions. 74 of the 84 overrides on a linac equipped with a 6D couch were due to the use of the rotational corrections and the fact that the 6D couch control does not communicate with the R&V system; translations required to rotate the couch appear to the R&V system as translations outside the tolerance range. Conclusion: Many findings were interesting but did not suggest a process change. Proposed process changes include creating site-specific instead of just technique-specific tolerance tables for couch shifts. Proposed improvements to the vendor are to facilitate direct communication between the 6D couch and the R&V system to eliminate those override warnings related to lack of communication.« less
Safety evaluation of intersection conflict warning systems (ICWS), TechBrief
DOT National Transportation Integrated Search
2016-02-02
The Federal Highway Administration (FHWA) organized 40 States to participate in the FHWA Evaluation of LowCost Safety Improvements Pooled Fund Study (ELCSI-PFS) as part of its strategic highway safety plan support effort. The goal of the ELCSI-PFS re...
DOT National Transportation Integrated Search
2012-07-01
This document describes the system requirements for three connected vehicle V2I safety applications related to intersection safety and speed management. Specifically, these applications include: Red-Light Violation Warning (RLVW) Stop Sign Ga...
Fifty years of driving safety research.
Lee, John D
2008-06-01
This brief review covers the 50 years of driving-related research published in Human Factors, its contribution to driving safety, and emerging challenges. Many factors affect driving safety, making it difficult to assess the impact of specific factors such as driver age, cell phone distractions, or collision warnings. The author considers the research themes associated with the approximately 270 articles on driving published in Human Factors in the past 50 years. To a large extent, current and past research has explored similar themes and concepts. Many articles published in the first 25 years focused on issues such as driver impairment, individual differences, and perceptual limits. Articles published in the past 25 years address similar issues but also point toward vehicle technology that can exacerbate or mitigate the negative effect of these issues. Conceptual and computational models have played an important role in this research. Improved crash-worthiness has contributed to substantial improvements in driving safety over the past 50 years, but future improvements will depend on enhancing driver performance and perhaps, more important, improving driver behavior. Developing models to guide this research will become more challenging as new technology enters the vehicle and shifts the focus from driver performance to driver behavior. Over the past 50 years, Human Factors has accumulated a large base of driving-related research that remains relevant for many of today's design and policy concerns.
The application of a piezo-resistive cardiorespiratory sensor system in an automobile safety belt.
Hamdani, Syed Talha Ali; Fernando, Anura
2015-03-30
Respiratory and heart failure are conditions that can occur with little warning and may also be difficult to predict. Therefore continuous monitoring of these bio-signals is advantageous for ensuring human health. The car safety belt is mainly designed to secure the occupants of the vehicle in the event of an accident. In the current research a prototype safety belt is developed, which is used to acquire respiratory and heart signals, under laboratory conditions. The current safety belt is constructed using a copper ink based nonwoven material, which works based on the piezo-resistive effect due to the pressure exerted on the sensor as a result of expansion of the thorax/abdomen area of the body for respiration and due to the principle of ballistocardiography (BCG) in heart signal sensing. In this research, the development of a theoretical model to qualitatively describe the piezo-resistive material is also presented in order to predict the relative change in the resistance of the piezo-resistive material due to the pressure applied.
Highway Performance Monitoring System reassessment
DOT National Transportation Integrated Search
2012-05-01
This document describes the concept of operations for three connected vehicle V2I safety applications related to intersection safety and speed management. Specifically, these applications include: Red-Light Violation Warning (RLVW) Stop Sign ...
Working together to ensure safety at hydro projects
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bartel, J.W.
Providing for public safety around a hydroelectric facility can be critically important to the welfare of a hydro-power producer. With this in mind, Wisconsin Electric Power Company and Wisconsin Public Service Corporation have worked together to develop consistent safety signage and several for their hydro projects. Although the two utilities sometimes compete for electric customers, they cooperate to ensure the safety to those customers. Both WE and WPS took steps in 1986 to make their operations safer through involvement in the Wisconsin/Michigan Hydro User Group. The organization has 25 members-primarily of electric utilities and paper companies-who operate hydro facilities inmore » the two states. The two areas that the HUG studied in public safety were signs and warning systems. HUG established a sign committee to study how to increase safety of people around hydro plants through signs, explained Ted Handrick, hydro plant superintendent at WPS. The committee's recommendations led to development of a statewide uniform sign system adopted by all HUG members. The committee used Wisconsin Department of Natural Resources' guidelines for warning signs and portages in developing the signage standards. HUG members are converting to these new sign standards as they replace old signs and/or install new signs. Notices describing the new signage system have been placed near each hydro plant, at boat landings, and in campgrounds. The signs are mounted well above ground level so they can be seen and easily read by recreationalists. Warning systems, in accordance with HUG warning standards, were installed at WE and WPS hydro facilities. These systems alert nearby recreational users of rapid increases in water flow when generating units are turned on or when spillway gates are opened. Soon after the authors installed equipment to remotely operate its hydro facilities, the utility experienced a dramatic increase increase in intrusion on dams and other structures at the projects.« less
NASA Technical Reports Server (NTRS)
1972-01-01
Safety requirements and guidelines are listed for the sortie module, upper stage vehicle, and space station for the earth orbit operations of the space shuttle program. The requirements and guidelines are for vehicle design, safety devices, warning devices, operational procedures, and residual hazards.
23 CFR 970.212 - Federal lands safety management system (SMS).
Code of Federal Regulations, 2011 CFR
2011-04-01
...) An inventory of safety appurtenances such as signs, delineators, and guardrails (including terminals... upgrading safety appurtenances including highway-rail crossing warning devices, signs, highway elements, and... standards) for low volume roads may be tailored to be consistent with the functional classification of the...
23 CFR 970.212 - Federal lands safety management system (SMS).
Code of Federal Regulations, 2012 CFR
2012-04-01
...) An inventory of safety appurtenances such as signs, delineators, and guardrails (including terminals... upgrading safety appurtenances including highway-rail crossing warning devices, signs, highway elements, and... standards) for low volume roads may be tailored to be consistent with the functional classification of the...
23 CFR 970.212 - Federal lands safety management system (SMS).
Code of Federal Regulations, 2013 CFR
2013-04-01
...) An inventory of safety appurtenances such as signs, delineators, and guardrails (including terminals... upgrading safety appurtenances including highway-rail crossing warning devices, signs, highway elements, and... standards) for low volume roads may be tailored to be consistent with the functional classification of the...
23 CFR 970.212 - Federal lands safety management system (SMS).
Code of Federal Regulations, 2014 CFR
2014-04-01
...) An inventory of safety appurtenances such as signs, delineators, and guardrails (including terminals... upgrading safety appurtenances including highway-rail crossing warning devices, signs, highway elements, and... standards) for low volume roads may be tailored to be consistent with the functional classification of the...
Is More Better? - Night Vision Enhancement System's Pedestrian Warning Modes and Older Drivers.
Brown, Timothy; He, Yefei; Roe, Cheryl; Schnell, Thomas
2010-01-01
Pedestrian fatalities as a result of vehicle collisions are much more likely to happen at night than during day time. Poor visibility due to darkness is believed to be one of the causes for the higher vehicle collision rate at night. Existing studies have shown that night vision enhancement systems (NVES) may improve recognition distance, but may increase drivers' workload. The use of automatic warnings (AW) may help minimize workload, improve performance, and increase safety. In this study, we used a driving simulator to examine performance differences of a NVES with six different configurations of warning cues, including: visual, auditory, tactile, auditory and visual, tactile and visual, and no warning. Older drivers between the ages of 65 and 74 participated in the study. An analysis based on the distance to pedestrian threat at the onset of braking response revealed that tactile and auditory warnings performed the best, while visual warnings performed the worst. When tactile or auditory warnings were presented in combination with visual warning, their effectiveness decreased. This result demonstrated that, contrary to general sense regarding warning systems, multi-modal warnings involving visual cues degraded the effectiveness of NVES for older drivers.
Is More Better? — Night Vision Enhancement System’s Pedestrian Warning Modes and Older Drivers
Brown, Timothy; He, Yefei; Roe, Cheryl; Schnell, Thomas
2010-01-01
Pedestrian fatalities as a result of vehicle collisions are much more likely to happen at night than during day time. Poor visibility due to darkness is believed to be one of the causes for the higher vehicle collision rate at night. Existing studies have shown that night vision enhancement systems (NVES) may improve recognition distance, but may increase drivers’ workload. The use of automatic warnings (AW) may help minimize workload, improve performance, and increase safety. In this study, we used a driving simulator to examine performance differences of a NVES with six different configurations of warning cues, including: visual, auditory, tactile, auditory and visual, tactile and visual, and no warning. Older drivers between the ages of 65 and 74 participated in the study. An analysis based on the distance to pedestrian threat at the onset of braking response revealed that tactile and auditory warnings performed the best, while visual warnings performed the worst. When tactile or auditory warnings were presented in combination with visual warning, their effectiveness decreased. This result demonstrated that, contrary to general sense regarding warning systems, multi-modal warnings involving visual cues degraded the effectiveness of NVES for older drivers. PMID:21050616
Winter Weather: Outdoor Safety
... Hot Weather Tips Warning Signs and Symptoms FAQs Social Media How to Stay Cool Missouri Cooling Centers Extreme ... PSAs for Disasters Resources for Emergency Health Professionals Social Media Health and Safety Concerns for All Disasters Animals ...
Human factors research problems in electronic voice warning system design
NASA Technical Reports Server (NTRS)
Simpson, C. A.; Williams, D. H.
1975-01-01
The speech messages issued by voice warning systems must be carefully designed in accordance with general principles of human decision making processes, human speech comprehension, and the conditions in which the warnings can occur. The operator's effectiveness must not be degraded by messages that are either inappropriate or difficult to comprehend. Important experimental variables include message content, linguistic redundancy, signal/noise ratio, interference with concurrent tasks, and listener expectations generated by the pragmatic or real world context in which the messages are presented.
2006-06-01
nuclear disaster warning systems,” and “preparedness and planning to reduce the consequences of major terrorist incidents.” In addition, the order...assistance functions,” in addition to dam safety, “natural and nuclear disaster warning systems,” and “the coordination of preparedness and planning to
49 CFR 214.511 - Required audible warning devices for new on-track roadway maintenance machines.
Code of Federal Regulations, 2011 CFR
2011-10-01
... roadway maintenance machines. 214.511 Section 214.511 Transportation Other Regulations Relating to... SAFETY On-Track Roadway Maintenance Machines and Hi-Rail Vehicles § 214.511 Required audible warning devices for new on-track roadway maintenance machines. Each new on-track roadway maintenance machine shall...
49 CFR 214.511 - Required audible warning devices for new on-track roadway maintenance machines.
Code of Federal Regulations, 2010 CFR
2010-10-01
... roadway maintenance machines. 214.511 Section 214.511 Transportation Other Regulations Relating to... SAFETY On-Track Roadway Maintenance Machines and Hi-Rail Vehicles § 214.511 Required audible warning devices for new on-track roadway maintenance machines. Each new on-track roadway maintenance machine shall...
21 CFR 369.10 - Conspicuousness of warning statements.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Conspicuousness of warning statements. 369.10... (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.10 Conspicuousness of warning statements. Necessary...
21 CFR 369.10 - Conspicuousness of warning statements.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Conspicuousness of warning statements. 369.10... (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.10 Conspicuousness of warning statements. Necessary...
21 CFR 369.10 - Conspicuousness of warning statements.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Conspicuousness of warning statements. 369.10... (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.10 Conspicuousness of warning statements. Necessary...
21 CFR 369.10 - Conspicuousness of warning statements.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Conspicuousness of warning statements. 369.10... (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.10 Conspicuousness of warning statements. Necessary...
21 CFR 369.10 - Conspicuousness of warning statements.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Conspicuousness of warning statements. 369.10... (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.10 Conspicuousness of warning statements. Necessary...
Development of a consortium for water security and safety: Planning for an early warning system
Clark, R.M.; Adam, N.R.; Atluri, V.; Halem, M.; Vowinkel, E.F.; ,
2004-01-01
The events of September 11, 2001 have raised concerns over the safety and security of the Nation's critical infrastructure including water and waste water systems. In June 2002, the U.S. EPA's Region II Office (New York City), in response to concerns over water security, in collaboration with Rutgers University agreed to establish a Regional Drinking Water Security and Safety Consortium (RDWSSC). Members of the consortium include: Rutgers University's Center for Information Management, Integration and Connectivity (CIMIC), American Water (AW), the Passaic Valley Water Commission (PVWC), the North Jersey District Water Supply Commission (NJDWSC), the N.J. Department of Environmental Protection, the U.S. Geological Survey (USGS), and the U.S. Environmental Protection Agencies, Region II Office. In December of 2002 the consortium members signed a memorandum of understanding (MOU) to pursue activities to enhance regional water security. Development of an early warning system for source and distributed water was identified as being of primary importance by the consortium. In this context, an early warning system (EWS) is an integrated system of monitoring stations located at strategic points in a water utilities source waters or in its distribution system, designed to warn against contaminants that might threaten the health and welfare of drinking water consumers. This paper will discuss the consortium's progress in achieving these important objectives.
NASA Technical Reports Server (NTRS)
Obrien, Maureen E.
1990-01-01
Telerobotic operations, whether under autonomous or teleoperated control, require a much more sophisticated safety system than that needed for most industrial applications. Industrial robots generally perform very repetitive tasks in a controlled, static environment. The safety system in that case can be as simple as shutting down the robot if a human enters the work area, or even simply building a cage around the work space. Telerobotic operations, however, will take place in a dynamic, sometimes unpredictable environment, and will involve complicated and perhaps unrehearsed manipulations. This creates a much greater potential for damage to the robot or objects in its vicinity. The Procedural Safety System (PSS) collects data from external sensors and the robot, then processes it through an expert system shell to determine whether an unsafe condition or potential unsafe condition exists. Unsafe conditions could include exceeding velocity, acceleration, torque, or joint limits, imminent collision, exceeding temperature limits, and robot or sensor component failure. If a threat to safety exists, the operator is warned. If the threat is serious enough, the robot is halted. The PSS, therefore, uses expert system technology to enhance safety thus reducing operator work load, allowing him/her to focus on performing the task at hand without the distraction of worrying about violating safety criteria.
30 CFR 57.4363 - Underground evacuation instruction.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Section 57.4363 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire... and evacuation plans and procedures and fire warning signals in effect at the mine. (b) Whenever a...
Brennan, Peter A; Brands, Marieke T; Caldwell, Lucy; Fonseca, Felipe Paiva; Turley, Nic; Foley, Susie; Rahimi, Siavash
2018-02-01
Essential communication between healthcare staff is considered one of the key requirements for both safety and quality care when patients are handed over from one clinical area to other. This is particularly important in environments such as the operating theatre and intensive care where mistakes can be devastating. Health care has learned from other high-risk organisations (HRO) such as aviation where the use of checklists and human factors awareness has virtually eliminated human error and mistakes. To our knowledge, little has been published around ways to improve pathology specimen handover following surgery, with pathology request forms often conveying the bare minimum of information to assist the laboratory staff. Furthermore, the request form might not warn staff about potential hazards. In this article, we provide a brief summary of the factors involved in human error and introduce a novel checklist that can be readily completed at the same time as the routine pathology request form. This additional measure enhances safety, can help to reduce processing and mislabelling errors and provides essential information in a structured way assisting both laboratory staff and pathologists when handling head and neck surgical specimens. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
21 CFR 369.9 - General warnings re accidental ingestion by children.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 5 2012-04-01 2012-04-01 false General warnings re accidental ingestion by... SERVICES (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.9 General warnings re accidental ingestion...
21 CFR 369.7 - Warnings required by official compendia.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Warnings required by official compendia. 369.7... (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.7 Warnings required by official compendia. Any drug...
21 CFR 369.7 - Warnings required by official compendia.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Warnings required by official compendia. 369.7... (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.7 Warnings required by official compendia. Any drug...
21 CFR 369.9 - General warnings re accidental ingestion by children.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 5 2011-04-01 2011-04-01 false General warnings re accidental ingestion by... SERVICES (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.9 General warnings re accidental ingestion...
21 CFR 369.7 - Warnings required by official compendia.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Warnings required by official compendia. 369.7... (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.7 Warnings required by official compendia. Any drug...
21 CFR 369.7 - Warnings required by official compendia.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Warnings required by official compendia. 369.7... (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.7 Warnings required by official compendia. Any drug...
21 CFR 369.7 - Warnings required by official compendia.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Warnings required by official compendia. 369.7... (CONTINUED) DRUGS FOR HUMAN USE INTERPRETATIVE STATEMENTS RE WARNINGS ON DRUGS AND DEVICES FOR OVER-THE-COUNTER SALE Definitions and Interpretations § 369.7 Warnings required by official compendia. Any drug...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-05
...] Draft Guidance for Industry on Organ-Specific Warnings: Internal Analgesic, Antipyretic, and... Warnings: Internal Analgesic, Antipyretic, and Antirheumatic Drug Products for Over-the-Counter Human Use... enforcement discretion with regard to the liver warning required in the labeling. DATES: Although you can...
21 CFR 330.2 - Pregnancy-nursing warning.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Pregnancy-nursing warning. 330.2 Section 330.2 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS... AND NOT MISBRANDED General Provisions § 330.2 Pregnancy-nursing warning. A pregnancy-nursing warning...
21 CFR 330.2 - Pregnancy-nursing warning.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Pregnancy-nursing warning. 330.2 Section 330.2 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS... AND NOT MISBRANDED General Provisions § 330.2 Pregnancy-nursing warning. A pregnancy-nursing warning...
21 CFR 330.2 - Pregnancy-nursing warning.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Pregnancy-nursing warning. 330.2 Section 330.2 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS... AND NOT MISBRANDED General Provisions § 330.2 Pregnancy-nursing warning. A pregnancy-nursing warning...
21 CFR 330.2 - Pregnancy-nursing warning.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Pregnancy-nursing warning. 330.2 Section 330.2 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS... AND NOT MISBRANDED General Provisions § 330.2 Pregnancy-nursing warning. A pregnancy-nursing warning...
21 CFR 330.2 - Pregnancy-nursing warning.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Pregnancy-nursing warning. 330.2 Section 330.2 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS... AND NOT MISBRANDED General Provisions § 330.2 Pregnancy-nursing warning. A pregnancy-nursing warning...
Women in Transportation: Changing America's History - Reference Materials
DOT National Transportation Integrated Search
2013-03-01
This document describes the system requirements for two connected vehicle V2I safety applications related to work zone safety and speed management. Specifically, these applications are: Spot Weather Information Warning (SWIW) Reduced Speed Zo...
DOT National Transportation Integrated Search
1971-01-01
Signing that effectively warns the motorist of temporary obstructions on or near a roadway is essential to traffic safety. The general objective of this study was to become familiar with and investigate the suitability of various temporary maintenanc...
30 CFR 57.3200 - Correction of hazardous conditions.
Code of Federal Regulations, 2010 CFR
2010-07-01
... permitted in the affected area. Until corrective work is completed, the area shall be posted with a warning... Section 57.3200 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Ground...
Malouff, John M.; Johnson, Caitlin E.; Rooke, Sally E.
2016-01-01
Abstract Introduction: Although cannabis use creates health risks, governments have recently been legalizing either medical use or leisure use. These governments can mandate health warnings on cannabis packages. Prior research examined recommended warnings of cannabis experts. The aim of this study was to obtain suggested cannabis health and safety warnings from cannabis users. Methods: We used a media release, Facebook postings, and announcements in university classes to seek individuals who had used cannabis at least once according to their own report. Using online data collection software that keeps participants anonymous, we asked the individuals to suggest a warning that governments could mandate on cannabis packages. Results: In total, 288 users suggested warnings. Categorizing the warnings into content categories led to six warning topics: (1) risk of harm to mental health and psychological functioning; (2) risk of operating machinery while under the influence; (3) short-term physical side effects; (4) responsible use; (5) long-term negative physical effects; and (6) dependence, addiction, or abuse. The user-suggested warnings overlapped with six expert-recommended warnings identified in prior survey research and included two content areas that did not feature in expert-recommended warnings: short-term physical side effects and the importance of responsible use. Conclusions: The results are consistent with prior findings that some youths perceive cannabis use as potentially harmful. The current findings provide possible new content for warnings on cannabis packages. PMID:28861495
Malouff, John M; Johnson, Caitlin E; Rooke, Sally E
2016-01-01
Introduction: Although cannabis use creates health risks, governments have recently been legalizing either medical use or leisure use. These governments can mandate health warnings on cannabis packages. Prior research examined recommended warnings of cannabis experts. The aim of this study was to obtain suggested cannabis health and safety warnings from cannabis users. Methods: We used a media release, Facebook postings, and announcements in university classes to seek individuals who had used cannabis at least once according to their own report. Using online data collection software that keeps participants anonymous, we asked the individuals to suggest a warning that governments could mandate on cannabis packages. Results: In total, 288 users suggested warnings. Categorizing the warnings into content categories led to six warning topics: (1) risk of harm to mental health and psychological functioning; (2) risk of operating machinery while under the influence; (3) short-term physical side effects; (4) responsible use; (5) long-term negative physical effects; and (6) dependence, addiction, or abuse. The user-suggested warnings overlapped with six expert-recommended warnings identified in prior survey research and included two content areas that did not feature in expert-recommended warnings: short-term physical side effects and the importance of responsible use. Conclusions: The results are consistent with prior findings that some youths perceive cannabis use as potentially harmful. The current findings provide possible new content for warnings on cannabis packages.
What you don't know can hurt you: household products and events.
Leonard, S D; Wogalter, M S
2000-05-01
Product safety is affected by product design and by the knowledge of the user, either through the user's own background or through instructions and warnings presented with the product. Given adequate knowledge, warnings can serve primarily to remind individuals of the hazards and precautions that can be taken. This study examined people in the USA (represented by two diverse samples) to evaluate their knowledge about the hazards associated with common household products and situations using both multiple choice and open-ended surveys. The results indicated that the respondents were aware of a substantial number of hazards, but their knowledge often did not extend to the specific circumstances that could produce personal injury and property damage. Further, comparisons of cued and non-cued responses suggested some hazards are not well recognized without the cue. The results indicate warnings are needed both as reminders and to provide safety information.
Hancock, Holly E; Fisk, Arthur D; Rogers, Wendy A
2005-01-01
Two experiments were conducted to determine if age affects comprehension for explicit and implied warning information and, if so, to reveal the nature of such effects. Experiment 1 measured younger (18-23 years) and older (65-75 years) adults' comprehension for real-world warnings via a verification test presented immediately after reading the warnings or after a delay. In Experiment 2, younger (18-22 years) and older (64-76 years) participants also read fabricated warnings that were inconsistent with real-world knowledge. In both experiments, older adults frequently failed to infer the correct hazard and safety information. The older adults also had trouble understanding warning information even when it was explicitly stated (when no inferences were required), especially when memory demands were high and product-specific knowledge could not be used. That many of the older adults did not understand commonly used product warnings indicates that the wording on many household products is not conducive to being understood by everyone who uses them. Actual or potential applications of this research include the recommendation that designers of product labels, warnings, and instructions should consider minimizing memory load and maximizing opportunities for knowledge application when designing consumer warnings.
77 FR 53898 - Collection of Information Under Review by Office of Management and Budget
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-04
... following collections of information: 1625-0016, Welding and Hot Work Permits; Posting of Warning Signs.... Title: Welding and Hot Work Permits; Posting of Warning Signs. OMB Control Number: 1625-0016. Type of... facilities and vessels are in compliance with safety standards. A permit must be issued prior to welding or...
49 CFR Appendix A to Part 222 - Approved Supplementary Safety Measures
Code of Federal Regulations, 2010 CFR
2010-10-01
... crossings located within New Partial Quiet Zones shall be closed from 10 p.m. until 7 a.m. every day. Public... apply only to New Quiet Zones or New Partial Quiet Zones. Constant warning time devices and power-out...-Rule Partial Quiet Zones are renewed, or new automatic warning device systems are installed, power-out...
49 CFR 193.2507 - Monitoring operations.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS FACILITIES... watching or listening from an attended control center for warning alarms, such as gas, temperature...
Forward Collision Warning Systems (CWS)
DOT National Transportation Integrated Search
2005-07-01
The Federal Motor Carrier Safety Administrations (FMCSAs) safety goal is to reduce the number and severity of large truck fatalities and crashes. During the last several years, FMCSA has collaborated with the trucking industry to test and evalu...
Early warning signals of regime shifts in coupled human–environment systems
Bauch, Chris T.; Sigdel, Ram; Pharaon, Joe; Anand, Madhur
2016-01-01
In complex systems, a critical transition is a shift in a system’s dynamical regime from its current state to a strongly contrasting state as external conditions move beyond a tipping point. These transitions are often preceded by characteristic early warning signals such as increased system variability. However, early warning signals in complex, coupled human–environment systems (HESs) remain little studied. Here, we compare critical transitions and their early warning signals in a coupled HES model to an equivalent environment model uncoupled from the human system. We parameterize the HES model, using social and ecological data from old-growth forests in Oregon. We find that the coupled HES exhibits a richer variety of dynamics and regime shifts than the uncoupled environment system. Moreover, the early warning signals in the coupled HES can be ambiguous, heralding either an era of ecosystem conservationism or collapse of both forest ecosystems and conservationism. The presence of human feedback in the coupled HES can also mitigate the early warning signal, making it more difficult to detect the oncoming regime shift. We furthermore show how the coupled HES can be “doomed to criticality”: Strategic human interactions cause the system to remain perpetually in the vicinity of a collapse threshold, as humans become complacent when the resource seems protected but respond rapidly when it is under immediate threat. We conclude that the opportunities, benefits, and challenges of modeling regime shifts and early warning signals in coupled HESs merit further research. PMID:27815533
Safety evaluation of curve warning speed signs.
DOT National Transportation Integrated Search
2011-06-01
This report presents a review of a research effort to evaluate the safety implications of advisory speeds at horizontal curve locations on Oregon rural two-lane highways. The primary goals of this research effort were to characterize driving operatio...
Hagiwara, Hiromi; Nakano, Shun; Ogawa, Yoshihiro; Tohkin, Masahiro
2015-06-01
We evaluated the effectiveness of warning letters published by the pharmaceutical regulatory agency in Japan on communication of drug safety and risk by quantitative analysis of the national health insurance claims database (NHICD). We then explored what factors may have affected risk communication. We measured the implementation rate of the hepatitis virus-monitoring test among methotrexate (MTX)-treated patients; a warning letter had been issued regarding the use of MTX, as it apparently activates the hepatitis virus. Data from the NHICD, which include 99·3% of Japanese residents, were used. A total of 4,933,481 patients with rheumatoid arthritis (RA) (January-June, 2010) were the focus of this study. The implementation rate of the hepatitis virus-monitoring test increased from 1·4% before to 1·8% after the warning letter announcement. Logistic regression analysis suggested that the installation of a drug information management room is one of the important factors affecting risk communication. Further analysis revealed that the hepatitis virus monitoring rates in hospitals without drug information management rooms increased from 2·3% to 4·1% due to the issue of the warning letter. The warning letter from the regulatory agency plays an important role in risk communication in hospitals without drug information management rooms. © 2015 John Wiley & Sons Ltd.
NASA Technical Reports Server (NTRS)
1981-01-01
The impact of modern technology on the role, responsibility, authority, and performance of human operators in modern aircraft and ATC systems was examined in terms of principles defined by Paul Fitts. Research into human factors in aircraft operations and the use of human factors engineering for aircraft safety improvements were discussed, and features of the man-machine interface in computerized cockpit warning systems are examined. The design and operational features of computerized avionics displays and HUDs are described, along with results of investigations into pilot decision-making behavior, aircrew procedural compliance, and aircrew judgment training programs. Experiments in vision and visual perception are detailed, as are behavioral studies of crew workload, coordination, and complement. The effectiveness of pilot selection, screening, and training techniques are assessed, as are methods for evaluating pilot performance.
DOT National Transportation Integrated Search
2016-05-05
Train-vehicle/train collisions at highway-rail grade crossings (crossings) continue to be a major issue in the US and around the world. Although the United States has made great strides in improving safety at crossings since the 1970s, vehicle-train ...
In-vehicle crash avoidance warning systems : human factors considerations
DOT National Transportation Integrated Search
1997-02-01
This document represents the final report of the work performed under contract DTNH22-91 C-07004, In-Vehicle Crash Avoidance Warning Systems: Human Factors Considerations. This project was performed to develop guidelines for the interface desig...
76 FR 27882 - Safety Standard for Toddler Beds
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-13
..., must meet the warning requirements specified in section 8 of ASTM F 1169-10, instead of the... toddler bed that can convert from a full-size crib, and has the warning specified in section 8.1.3 of ASTM.... (7) In addition to figure 10 of ASTM F 1821-09, use the following: [FR Doc. C1-2011-9421 Filed 5-12...
Intelligent tires for improved tire safety using wireless strain measurement
NASA Astrophysics Data System (ADS)
Matsuzaki, Ryosuke; Todoroki, Akira
2008-03-01
From a traffic safety point-of-view, there is an urgent need for intelligent tires as a warning system for road conditions, for optimized braking control on poor road surfaces and as a tire fault detection system. Intelligent tires, equipped with sensors for monitoring applied strain, are effective in improving reliability and control systems such as anti-lock braking systems (ABSs). In previous studies, we developed a direct tire deformation or strain measurement system with sufficiently low stiffness and high elongation for practical use, and a wireless communication system between tires and vehicle that operates without a battery. The present study investigates the application of strain data for an optimized braking control and road condition warning system. The relationships between strain sensor outputs and tire mechanical parameters, including braking torque, effective radius and contact patch length, are calculated using finite element analysis. Finally, we suggested the possibility of optimized braking control and road condition warning systems. Optimized braking control can be achieved by keeping the slip ratio constant. The road condition warning would be actuated if the recorded friction coefficient at a certain slip ratio is lower than a 'safe' reference value.
CSPMS supported by information technology
NASA Astrophysics Data System (ADS)
Zhang, Hudan; Wu, Heng
This paper will propose a whole new viewpoint about building a CSPMS(Coal-mine Safety Production Management System) by means of information technology. This system whose core part is a four-grade automatic triggered warning system achieves the goal that information transmission will be smooth, nondestructive and in time. At the same time, the system provides a comprehensive and collective technology platform for various Public Management Organizations and coal-mine production units to deal with safety management, advance warning, unexpected incidents, preplan implementation, and resource deployment at different levels. The database of this system will support national related industry's resource control, plan, statistics, tax and the construction of laws and regulations effectively.
Volvo drivers' experiences with advanced crash avoidance and related technologies.
Eichelberger, Angela H; McCartt, Anne T
2014-01-01
Crash avoidance technologies can potentially prevent or mitigate many crashes, but their success depends in part on driver acceptance. Owners of 2010-2012 model Volvo vehicles with several technologies were interviewed about their experiences. Interviews were conducted in summer 2012 with 155 owners of vehicles with City Safety as a standard feature; 145 owners with an optional technology package that included adaptive cruise control, distance alert, collision warning with full auto brake (and pedestrian detection on certain models), driver alert control, and lane departure warning; and 172 owners with both City Safety and the technology package. The survey response rates were 21 percent for owners with City Safety, 30 percent for owners with the technology package, and 27 percent for owners with both. Ten percent of owners opted out before the telephone survey began, and 18 percent declined to participate when called. Despite some annoyance, most respondents always leave the systems on, although fewer do so for lane departure warning (59%). For each of the systems, at least 80 percent of respondents with the system would want it on their next vehicle. Many respondents reported safer driving habits with the systems (e.g., following less closely with adaptive cruise control, using turn signals more often with lane departure warning). Fewer respondents reported potentially unsafe behavior, such as allowing the vehicle to brake for them at least some of the time. About one third of respondents experienced autonomous braking when they believed they were at risk of crashing, and about one fifth of respondents thought it had prevented a crash. About one fifth of respondents with the technology package reported that they were confused or misunderstood which safety system had activated in their vehicle. Consistent with the results for early adopters in the previous survey of Volvo and Infiniti owners, the present survey found that driver acceptance of the technologies remains high, although less so for lane departure warning. This study is the first to report drivers' experiences with City Safety, a collision avoidance system provided as standard equipment on certain Volvo 2010-2012 models, and driver acceptance of this system was high, although not to the same extent as the optional forward collision avoidance system. Future research should continue to monitor drivers' experiences with these technologies as they become available in more vehicles.
Safety evaluation of joint and conventional lane merge configurations for freeway work zones.
Ishak, Sherif; Qi, Yan; Rayaprolu, Pradeep
2012-01-01
Inefficient operation of traffic in work zone areas not only leads to an increase in travel time delays, queue length, and fuel consumption but also increases the number of forced merges and roadway accidents. This study evaluated the safety performance of work zones with a conventional lane merge (CLM) configuration in Louisiana. Analysis of variance (ANOVA) was used to compare the crash rates for accidents involving fatalities, injuries, and property damage only (PDO) in each of the following 4 areas: (1) advance warning area, (2) transition area, (3) work area, and (4) termination area. The analysis showed that the advance warning area had higher fatality, injury, and PDO crash rates when compared to the transition area, work area, and termination area. This finding confirmed the need to make improvements in the advance warning area where merging maneuvers take place. Therefore, a new lane merge configuration, called joint lane merge (JLM), was proposed and its safety performance was examined and compared to the conventional lane merge configuration using a microscopic simulation model (VISSIM), which was calibrated with real-world data from an existing work zone on I-55 and used to simulate a total of 25 different scenarios with different levels of demand and traffic composition. Safety performance was evaluated using 2 surrogate measures: uncomfortable decelerations and speed variance. Statistical analysis was conducted to determine whether the differences in safety performance between both configurations were significant. The safety analysis indicated that JLM outperformed CLM in most cases with low to moderate flow rates and that the percentage of trucks did not have a significant impact on the safety performance of either configuration. Though the safety analysis did not clearly indicate which lane merge configuration is safer for the overall work zone area, it was able to identify the possibly associated safety changes within the work zone area under different traffic conditions. Copyright © 2012 Taylor & Francis Group, LLC
Implementing Obstetric Early Warning Systems.
Friedman, Alexander M; Campbell, Mary L; Kline, Carolyn R; Wiesner, Suzanne; D'Alton, Mary E; Shields, Laurence E
2018-04-01
Severe maternal morbidity and mortality are often preventable and obstetric early warning systems that alert care providers of potential impending critical illness may improve maternal safety. While literature on outcomes and test characteristics of maternal early warning systems is evolving, there is limited guidance on implementation. Given current interest in early warning systems and their potential role in care, the 2017 Society for Maternal-Fetal Medicine (SMFM) Annual Meeting dedicated a session to exploring early warning implementation across a wide range of hospital settings. This manuscript reports on key points from this session. While implementation experiences varied based on factors specific to individual sites, common themes relevant to all hospitals presenting were identified. Successful implementation of early warnings systems requires administrative and leadership support, dedication of resources, improved coordination between nurses, providers, and ancillary staff, optimization of information technology, effective education, evaluation of and change in hospital culture and practices, and support in provider decision-making. Evolving data on outcomes on early warning systems suggest that maternal risk may be reduced. To effectively reduce maternal, risk early warning systems that capture deterioration from a broad range of conditions may be required in addition to bundles tailored to specific conditions such as hemorrhage, thromboembolism, and hypertension.
Summary of DOT Rail-Highway Crossing Resource Allocation Procedure - Revised
DOT National Transportation Integrated Search
1987-06-01
The Highway Safety Acts of 1973 and 1976, and the Surface Transportation Assistance Acts of 1978 and 1982 provide funding authorizations to individual states to improve safety at public rail-highway crossings. The installation of active motorist warn...
Safety belt interlock system usage survey
DOT National Transportation Integrated Search
1976-08-01
This research is intended to measure the effectiveness of various use-inducing systems in increasing safety belt usage. Specifically, the objectives are: (1) to determine if the 1975 warning system issued in response to P.L. 93-492 is effective in in...
Washington, Simon; Oh, Jutaek
2006-03-01
Transportation professionals are sometimes required to make difficult transportation safety investment decisions in the face of uncertainty. In particular, an engineer may be expected to choose among an array of technologies and/or countermeasures to remediate perceived safety problems when: (1) little information is known about the countermeasure effects on safety; (2) information is known but from different regions, states, or countries where a direct generalization may not be appropriate; (3) where the technologies and/or countermeasures are relatively untested, or (4) where costs prohibit the full and careful testing of each of the candidate countermeasures via before-after studies. The importance of an informed and well-considered decision based on the best possible engineering knowledge and information is imperative due to the potential impact on the numbers of human injuries and deaths that may result from these investments. This paper describes the formalization and application of a methodology to evaluate the safety benefit of countermeasures in the face of uncertainty. To illustrate the methodology, 18 countermeasures for improving safety of at grade railroad crossings (AGRXs) in the Republic of Korea are considered. Akin to "stated preference" methods in travel survey research, the methodology applies random selection and laws of large numbers to derive accident modification factor (AMF) densities from expert opinions. In a full Bayesian analysis framework, the collective opinions in the form of AMF densities (data likelihood) are combined with prior knowledge (AMF density priors) for the 18 countermeasures to obtain 'best' estimates of AMFs (AMF posterior credible intervals). The countermeasures are then compared and recommended based on the largest safety returns with minimum risk (uncertainty). To the author's knowledge the complete methodology is new and has not previously been applied or reported in the literature. The results demonstrate that the methodology is able to discern anticipated safety benefit differences across candidate countermeasures. For the 18 at grade railroad crossings considered in this analysis, it was found that the top three performing countermeasures for reducing crashes are in-vehicle warning systems, obstacle detection systems, and constant warning time systems.
Indications and Warning Methodology for Strategic Intelligence
2017-12-01
WARNING METHODOLOGY FOR STRATEGIC INTELLIGENCE by Susann Kimmelman December 2017 Thesis Co-Advisors: Robert Simeral James Wirtz THIS...Master’s thesis 4. TITLE AND SUBTITLE INDICATIONS AND WARNING METHODOLOGY FOR STRATEGIC INTELLIGENCE 5. FUNDING NUMBERS 6. AUTHOR(S) Susann...enterprise. The research found that, for homeland security, implementing a human-centric indications and warning methodology that focuses on the actor as
Early warnings, weak signals and learning from healthcare disasters.
Macrae, Carl
2014-06-01
In the wake of healthcare disasters, such as the appalling failures of care uncovered in Mid Staffordshire, inquiries and investigations often point to a litany of early warnings and weak signals that were missed, misunderstood or discounted by the professionals and organisations charged with monitoring the safety and quality of care. Some of the most urgent challenges facing those responsible for improving and regulating patient safety are therefore how to identify, interpret, integrate and act on the early warnings and weak signals of emerging risks-before those risks contribute to a disastrous failure of care. These challenges are fundamentally organisational and cultural: they relate to what information is routinely noticed, communicated and attended to within and between healthcare organisations-and, most critically, what is assumed and ignored. Analysing these organisational and cultural challenges suggests three practical ways that healthcare organisations and their regulators can improve safety and address emerging risks. First, engage in practices that actively produce and amplify fleeting signs of ignorance. Second, work to continually define and update a set of specific fears of failure. And third, routinely uncover and publicly circulate knowledge on the sources of systemic risks to patient safety and the improvements required to address them. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
Chen, Yulong; Irfan, Muhammad; Uchimura, Taro; Zhang, Ke
2018-03-27
Rainfall-induced landslides are one of the most widespread slope instability phenomena posing a serious risk to public safety worldwide so that their temporal prediction is of great interest to establish effective warning systems. The objective of this study is to determine the effectiveness of elastic wave velocities in the surface layer of the slope in monitoring, prediction and early warning of landslide. The small-scale fixed and varied, and large-scale slope model tests were conducted. Analysis of the results has established that the elastic wave velocity continuously decreases in response of moisture content and deformation and there was a distinct surge in the decrease rate of wave velocity when failure was initiated. Based on the preliminary results of this analysis, the method using the change in elastic wave velocity proves superior for landslide early warning and suggests that a warning be issued at switch of wave velocity decrease rate.
The Application of a Piezo-Resistive Cardiorespiratory Sensor System in an Automobile Safety Belt
Hamdani, Syed Talha Ali; Fernando, Anura
2015-01-01
Respiratory and heart failure are conditions that can occur with little warning and may also be difficult to predict. Therefore continuous monitoring of these bio-signals is advantageous for ensuring human health. The car safety belt is mainly designed to secure the occupants of the vehicle in the event of an accident. In the current research a prototype safety belt is developed, which is used to acquire respiratory and heart signals, under laboratory conditions. The current safety belt is constructed using a copper ink based nonwoven material, which works based on the piezo-resistive effect due to the pressure exerted on the sensor as a result of expansion of the thorax/abdomen area of the body for respiration and due to the principle of ballistocardiography (BCG) in heart signal sensing. In this research, the development of a theoretical model to qualitatively describe the piezo-resistive material is also presented in order to predict the relative change in the resistance of the piezo-resistive material due to the pressure applied. PMID:25831088
The design of the intelligent monitoring system for dam safety
NASA Astrophysics Data System (ADS)
Yuan, Chun-qiao; Jiang, Chen-guang; Wang, Guo-hui
2008-12-01
Being a vital manmade water-control structure, a dam plays a very important role in the living and production of human being. To make a dam run safely, the best design and the superior construction quality are paramount; moreover, with working periods increasing, various dynamic, alternative and bad loads generate little by little various distortions on the dam structure inevitably, which shall lead to potential safety problems or further a disaster (dam burst). There are many signs before the occurrence of a dam accident, so the timely and effective surveying on the distortion of a dam is important. On the basis of the cause supra, two intelligent (automatic) monitoring systems about the dam's safety based on the RTK-GPS technology and the measuring robot has been developed. The basic principle, monitoring method and monitoring process of these two intelligent (automatic) monitoring systems are introduced. It presents examples of monitor and puts forward the basic rule of dam warning based on data of actual monitor.
78 FR 45052 - Critical Parts for Airplane Propellers; Correction
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-26
..., early warning devices, maintenance checks, and other similar equipment or procedures. If items of the..., and maintenance processes for propeller critical parts. An unintentional error was introduced in Sec... transportation, Aircraft, Aviation safety, Safety. The Correcting Amendment In consideration of the foregoing...
DOT National Transportation Integrated Search
2011-10-01
This report presents the methodology and results of the independent evaluation of a prototype integrated crash warning system for : light vehicles as part of the Integrated Vehicle-Based Safety Systems initiative of the United States Department of : ...
Remember, remember, firework safety.
1998-01-01
A&E nurses at Blackburn Royal Infirmary talk to local youngsters to warn them about the dangers of being reckless with fireworks. Sister Alison Walmsley (left) and auxiliary Frances Walsh are pictured giving safety tips to ten-year-old Louise Greenwood at the hospital's awareness stand.
Fire Won't Wait--Plan Your Escape!
ERIC Educational Resources Information Center
PTA Today, 1991
1991-01-01
Discusses the importance of home fire escape drills, detailing fire safety plans. Early detection and warning (smoke detectors) coupled with well-rehearsed escape plans help prevent serious injury. Children need to be taught about fire safety beginning at a very early age. (SM)
[Drug safety warnings in psychiatry: adverse drug reactions' signaling from 2002 to 2014].
Prisco, Vincenzo; Iannaccone, Teresa; Tusciano, Adriano; Boccardi, Mariangela; Perris, Francesco; Capuano, Annalisa; Catapano, Francesco; Fabrazzo, Michele
2016-01-01
Monitoring drug-related side effects in psychiatric patients is highly recommended. In fact, frequent exposure to long-term polipharmacotherapy, poor compliance to pharmachological treatment and comorbidity with organic illnesses requiring the prescription of other drugs are causes of pharmacokinetic/pharmacodynamic interactions. These vulnerability factors result in a certain increase in adverse drug reactions (ADRs). This study performes an analysis of Italian Medicine Agency data, in the section "signal analysis", to attempt an assessment of the safety warnings among the different psychotropic drug classes, belonging to the ATC class: N03 (antiepileptics), N05 (antipsychotics), N06 (psycho-analectic drugs). Then we analysed, in a descriptive way, the different association between the drug and the related ADR, evaluating the different safety profiles, in relation to experimental studies, supporting the importance of the signal. In the last years, among the new 25 ADRs, 10 were related to antidepressant drugs (8 SSRI, 1 mirtazapine, 1 agomelatine). In relation to antipsychotic drugs, 6 new correlations were found between drug and ADR onset, mainly among atypical antispychotics. Other correlations (6 above all) were found among antiepileptic drugs. Among benzodiazepines, a signal linked to rabdomylysis onset was found. It is also recommended an evaluation of safety profile in relation to zolpidem prescription. The results of our systematic review are a motivational input, considering the continuous increase of safety warnings, to attentively monitor drug's prescription. Spontaneous ADRs' signaling is a classical system to provide the required attention in relation to a potential risk. The clinician in charge must report this because he is the key figure in the drugs' safety process. In psychiatry, in which a long-term pharmachological therapy is frequent, clinicians are requested to find and signal ADRs to the competent authority.
Code of Federal Regulations, 2012 CFR
2012-04-01
... display of health warnings in an advertisement for cigarettes if the advertisement is not created by or on... open to the public, an advertisement that does not contain a health warning or that contains a warning... AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) TOBACCO PRODUCTS...
Risk management policy and black-box warnings: a qualitative analysis of US FDA proceedings.
Cook, Daniel M; Gurugubelli, Rama K; Bero, Lisa A
2009-01-01
The US FDA increasingly applies risk management to drug safety policy. Little is known about the process by which the FDA approves labelling changes. Although advisory committees can recommend any of the risk management tools, including the use of 'black-box warnings', it is unknown whether they deliberate on these questions or how they apply the principles of risk minimization or management during their considerations of drug licensing. To examine the process by which risk management is considered by the FDA, including the role of FDA advisory committees. We also aimed to identify and describe drug labelling changes and additions, including the prevalence of black-box warnings. We electronically obtained publicly available information regarding drug approvals, drug revisions and advisory committee meetings over 3 years (2004-6) from the FDA. Data in the form of meeting transcripts and full histories of labelling changes were collected on drugs discussed by advisory committees. We then searched and qualitatively analysed the meeting transcripts to identify themes in the discussion. We also created a database of all prescription drug labelling changes for 3 years and examined which drugs have had the most changes. We describe the risk management consideration process and report the frequency and characteristics of labelling changes. Excerpts from the transcripts are selected to illustrate both typical and atypical features of the discussion. A total of 174 black-box changes were made in the 3-year period of our study, of which 77 were new black-box warnings and 97 were revisions in black-box warnings. Of 77 new black-box warning additions, only 11 drugs were discussed by the advisory committees. Of the 17 most frequently revised drug labels in these 3 years, two were discussed in the advisory committee meetings. Advisory meeting discussions revealed confusion about black-box warnings and emphasized potential consequences of the warnings rather than their content. The safety labelling of drugs on the market is changed often. Panels of advisors consider only a few drugs, rarely discuss the labelling requirements, and display confusion about applying black-box warnings. The creation and application of black-box warnings on prescription medications should receive closer attention from the FDA and its advisors.
Era of faster FDA drug approval has also seen increased black-box warnings and market withdrawals.
Frank, Cassie; Himmelstein, David U; Woolhandler, Steffie; Bor, David H; Wolfe, Sidney M; Heymann, Orlaith; Zallman, Leah; Lasser, Karen E
2014-08-01
After approval, many prescription medications that patients rely on subsequently receive new black-box warnings or are withdrawn from the market because of safety concerns. We examined whether the frequency of these safety problems has increased since 1992, when the Prescription Drug User Fee Act, legislation designed to accelerate the drug approval process at the Food and Drug Administration, was passed. We found that drugs approved after the act's passage were more likely to receive a new black-box warning or be withdrawn than drugs approved before its passage (26.7 per 100.0 drugs versus 21.2 per 100.0 drugs at up to sixteen years of follow-up). We could not establish causality, however. Our findings suggest the need for reforms to reduce patients' exposure to unsafe drugs, such as a statement or symbol in the labeling, medication guides for patients, and marketing materials indicating that a drug was approved only recently. Project HOPE—The People-to-People Health Foundation, Inc.
21 CFR 814.82 - Postapproval requirements.
Code of Federal Regulations, 2010 CFR
2010-04-01
... periodic reporting on the safety, effectiveness, and reliability of the device for its intended use. FDA... a device and in the advertising of any restricted device of warnings, hazards, or precautions... extent required for the medical welfare of the individual, to determine the safety or effectiveness of...
Rail-Highway Crossing Warning Device Life Cycle Cost Analysis
DOT National Transportation Integrated Search
1980-09-01
The Highway Safety Acts of 1973 and 1976, and the Surface Transportation Assistance Act of 1978 provide funds to individual states to improve safety at public rail-highway crossings. This report was undertaken in support of a U.S. DOT effort to impro...
DOT National Transportation Integrated Search
1982-09-01
The Highway Safety Acts of 1973 and 1976, and the Surface Transportation Assistance Act of 1978, provide funding authorizations to individual states to improve safety at public rail-highway crossings. The installation of active motorist warning devic...
Training Requirements in OSHA Standards and Training Guidelines.
ERIC Educational Resources Information Center
Occupational Safety and Health Administration, Washington, DC.
This booklet contains Occupational Safety and Health Administration (OSHA) training requirements, excerpted from OSHA standards. The booklet is designed to help employers, safety and health professionals, training directors, and others who need to know training requirements. (Requirements for posting information, warning signs, labels, and the…
Ruscio, D; Bos, A J; Ciceri, M R
2017-06-01
The interaction with Advanced Driver Assistance Systems has several positive implications for road safety, but also some potential downsides such as mental workload and automation complacency. Malleable attentional resources allocation theory describes two possible processes that can generate workload in interaction with advanced assisting devices. The purpose of the present study is to determine if specific analysis of the different modalities of autonomic control of nervous system can be used to discriminate different potential workload processes generated during assisted-driving tasks and automation complacency situations. Thirty-five drivers were tested in a virtual scenario while using head-up advanced warning assistance system. Repeated MANOVA were used to examine changes in autonomic activity across a combination of different user interactions generated by the advanced assistance system: (1) expected take-over request without anticipatory warning; (2) expected take-over request with two-second anticipatory warning; (3) unexpected take-over request with misleading warning; (4) unexpected take-over request without warning. Results shows that analysis of autonomic modulations can discriminate two different resources allocation processes, related to different behavioral performances. The user's interaction that required divided attention under expected situations produced performance enhancement and reciprocally-coupled parasympathetic inhibition with sympathetic activity. At the same time, supervising interactions that generated automation complacency were described specifically by uncoupled sympathetic activation. Safety implications for automated assistance systems developments are considered. Copyright © 2017 Elsevier Ltd. All rights reserved.
Effectiveness and acceptance of the intelligent speeding prediction system (ISPS).
Zhao, Guozhen; Wu, Changxu
2013-03-01
The intelligent speeding prediction system (ISPS) is an in-vehicle speed assistance system developed to provide quantitative predictions of speeding. Although the ISPS's prediction of speeding has been validated, whether the ISPS can regulate a driver's speed behavior or whether a driver accepts the ISPS needs further investigation. Additionally, compared to the existing intelligent speed adaptation (ISA) system, whether the ISPS performs better in terms of reducing excessive speeds and improving driving safety needs more direct evidence. An experiment was conducted to assess and compare the effectiveness and acceptance of the ISPS and the ISA. We conducted a driving simulator study with 40 participants. System type served as a between-subjects variable with four levels: no speed assistance system, pre-warning system developed based on the ISPS, post-warning system ISA, and combined pre-warning and ISA system. Speeding criterion served as a within-subjects variable with two levels: lower (posted speed limit plus 1 mph) and higher (posted speed limit plus 5 mph) speed threshold. Several aspects of the participants' driving speed, speeding measures, lead vehicle response, and subjective measures were collected. Both pre-warning and combined systems led to greater minimum time-to-collision. The combined system resulted in slower driving speed, fewer speeding exceedances, shorter speeding duration, and smaller speeding magnitude. The results indicate that both pre-warning and combined systems have the potential to improve driving safety and performance. Copyright © 2012 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Gensch, S.; Wächter, J.; Schnor, B.
2014-12-01
Early warning systems (EWS) are safety-critical IT-infrastructures that serve the purpose of potentially saving lives or assets by observing real-world phenomena and issuing timely warning products to authorities and communities. An EWS consists of sensors, communication networks, data centers, simulation platforms, and dissemination channels. The components of this cyber-physical system may all be affected by both natural hazards and malfunctions of components alike. Resilience engineering so far has mostly been applied to safety-critical systems and processes in transportation (aviation, automobile), construction and medicine. Early warning systems need equivalent techniques to compensate for failures, and furthermore means to adapt to changing threats, emerging technology and research findings. We present threats and pitfalls from our experiences with the German and Indonesian tsunami early warning system, as well as architectural, technological and organizational concepts employed that can enhance an EWS' resilience. The current EWS is comprised of a multi-type sensor data upstream part, different processing and analysis engines, a decision support system, and various warning dissemination channels. Each subsystem requires a set of approaches towards ensuring stable functionality across system layer boundaries, including also institutional borders. Not only must services be available, but also produce correct results. Most sensors are distributed components with restricted resources, communication channels and power supply. An example for successful resilience engineering is the power capacity based functional management for buoy and tide gauge stations. We discuss various fault-models like cause and effect models on linear pathways, interaction of multiple events, complex and non-linear interaction of assumedly reliable subsystems and fault tolerance means implemented to tackle these threats.
Donley, Greer
Pregnant women are routinely faced with the stressful decision of whether to consume needed medications during their pregnancies. Because the risks associated with pharmaceutical drug consumption during pregnancy are largely unknown, pregnant women both inadvertently consume dangerous medications and avoid needed drugs. Both outcomes are harmful to pregnant women and their fetuses. This unparalleled lack of drug safety information is a result of ill-conceived, paternalistic regulations in two areas of the law: regulations governing ethical research in human subjects and regulations that dictate the required labels on drugs. The former categorizes pregnant women as "vulnerable" and thus precludes them from most medical research. The result is that ninety-one percent of drugs lack any reliable safety information for pregnant consumers. The latter currently requires all drug labels to encourage drug avoidance during pregnancy, despite ample evidence that avoiding needed medications can harm pregnant women. On June 30, 2015, new pregnancy labeling regulations took effect. Though these regulations make important improvements, they continue to treat pregnant women unlike any population, including other unique subpopulations, such as children. As a result, the new regulations do not fix the problem of over-warning pregnant women about the risks of drug consumption. This article questions the legitimacy of both regulations and suggests three reforms for how to improve access to vital safety information: (1) amend the regulations governing ethical research in human subjects to reclassify pregnant women as non-vulnerable adults; (2) create incentives to generate safety data in pregnant women by granting a period of market exclusivity for drug companies that invest in this research; and (3) make the FDA pregnancy labeling regulations consistent with the routine FDA practice of requiring the display of balanced, human data on risk.
Helicopter crashes into water: warning time, final position, and other factors affecting survival.
Brooks, Christopher J; MacDonald, Conor V; Baker, Susan P; Shanahan, Dennis F; Haaland, Wren L
2014-04-01
According to 40 yr of data, the fatality rate for a helicopter crash into water is approximately 25%. Does warning time and the final position of the helicopter in the water influence the survival rate? The National Transportation Safety Board (NTSB) database was queried to identify helicopter crashes into water between 1981 and 2011 in the Gulf of Mexico and Hawaii. Fatality rate, amount of warning time prior to the crash, and final position of the helicopter were identified. There were 133 helicopters that crashed into water with 456 crew and passengers. Of these, 119 occupants (26%) did not survive; of those who did survive, 38% were injured. Twelve died after making a successful escape from the helicopter. Crashes with < 15 s warning had a fatality rate of 22%, compared to 12% for 16-60 s warning and 5% for > 1 min. However, more than half of fatalities (57%) came from crashes for which the warning time could not be determined. Lack of warning time and how to survive in the water after the crash should be a topic for study in all marine survival/aircraft ditching courses. Investigators should be trained to provide estimates of warning time when investigating helicopter crashes into water.
Database for Safety-Oriented Tracking of Chemicals
NASA Technical Reports Server (NTRS)
Stump, Jacob; Carr, Sandra; Plumlee, Debrah; Slater, Andy; Samson, Thomas M.; Holowaty, Toby L.; Skeete, Darren; Haenz, Mary Alice; Hershman, Scot; Raviprakash, Pushpa
2010-01-01
SafetyChem is a computer program that maintains a relational database for tracking chemicals and associated hazards at Johnson Space Center (JSC) by use of a Web-based graphical user interface. The SafetyChem database is accessible to authorized users via a JSC intranet. All new chemicals pass through a safety office, where information on hazards, required personal protective equipment (PPE), fire-protection warnings, and target organ effects (TOEs) is extracted from material safety data sheets (MSDSs) and recorded in the database. The database facilitates real-time management of inventory with attention to such issues as stability, shelf life, reduction of waste through transfer of unused chemicals to laboratories that need them, quantification of chemical wastes, and identification of chemicals for which disposal is required. Upon searching the database for a chemical, the user receives information on physical properties of the chemical, hazard warnings, required PPE, a link to the MSDS, and references to the applicable International Standards Organization (ISO) 9000 standard work instructions and the applicable job hazard analysis. Also, to reduce the labor hours needed to comply with reporting requirements of the Occupational Safety and Health Administration, the data can be directly exported into the JSC hazardous- materials database.
Sefton, Gerri; Lane, Steven; Killen, Roger; Black, Stuart; Lyon, Max; Ampah, Pearl; Sproule, Cathryn; Loren-Gosling, Dominic; Richards, Caitlin; Spinty, Jean; Holloway, Colette; Davies, Coral; Wilson, April; Chean, Chung Shen; Carter, Bernie; Carrol, E D
2017-05-01
Pediatric Early Warning Scores are advocated to assist health professionals to identify early signs of serious illness or deterioration in hospitalized children. Scores are derived from the weighting applied to recorded vital signs and clinical observations reflecting deviation from a predetermined "norm." Higher aggregate scores trigger an escalation in care aimed at preventing critical deterioration. Process errors made while recording these data, including plotting or calculation errors, have the potential to impede the reliability of the score. To test this hypothesis, we conducted a controlled study of documentation using five clinical vignettes. We measured the accuracy of vital sign recording, score calculation, and time taken to complete documentation using a handheld electronic physiological surveillance system, VitalPAC Pediatric, compared with traditional paper-based charts. We explored the user acceptability of both methods using a Web-based survey. Twenty-three staff participated in the controlled study. The electronic physiological surveillance system improved the accuracy of vital sign recording, 98.5% versus 85.6%, P < .02, Pediatric Early Warning Score calculation, 94.6% versus 55.7%, P < .02, and saved time, 68 versus 98 seconds, compared with paper-based documentation, P < .002. Twenty-nine staff completed the Web-based survey. They perceived that the electronic physiological surveillance system offered safety benefits by reducing human error while providing instant visibility of recorded data to the entire clinical team.
30 CFR 56.4330 - Firefighting, evacuation, and rescue procedures.
Code of Federal Regulations, 2010 CFR
2010-07-01
... METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Fire Prevention and Control Firefighting Procedures/alarms/drills § 56.4330 Firefighting, evacuation... organizations. (b) Fire alarm procedures or systems shall be established to pomptly warn every person who could...
Informing Workers of Chemical Hazards: The OSHA Hazard Communication Standard.
ERIC Educational Resources Information Center
American Chemical Society, Washington, DC.
Practical information on how to implement a chemical-related safety program is outlined in this publication. Highlights of the federal Occupational Safety and Health Administrations (OSHA) Hazard Communication Standard are presented and explained. These include: (1) hazard communication requirements (consisting of warning labels, material safety…
48 CFR 252.223-7001 - Hazard warning labels.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...
48 CFR 252.223-7001 - Hazard warning labels.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...
48 CFR 252.223-7001 - Hazard warning labels.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...
48 CFR 252.223-7001 - Hazard warning labels.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...
48 CFR 252.223-7001 - Hazard warning labels.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...
44 CFR 206.62 - Available assistance.
Code of Federal Regulations, 2012 CFR
2012-10-01
... community services; (2) Issuance of warnings of risks or hazards; (3) Public health and safety information, including dissemination of such information; (4) Provision of health and safety measures; and (5) Management... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Available assistance. 206.62...
44 CFR 206.62 - Available assistance.
Code of Federal Regulations, 2011 CFR
2011-10-01
... community services; (2) Issuance of warnings of risks or hazards; (3) Public health and safety information, including dissemination of such information; (4) Provision of health and safety measures; and (5) Management... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Available assistance. 206.62...
44 CFR 206.62 - Available assistance.
Code of Federal Regulations, 2014 CFR
2014-10-01
... community services; (2) Issuance of warnings of risks or hazards; (3) Public health and safety information, including dissemination of such information; (4) Provision of health and safety measures; and (5) Management... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Available assistance. 206.62...
44 CFR 206.62 - Available assistance.
Code of Federal Regulations, 2013 CFR
2013-10-01
... community services; (2) Issuance of warnings of risks or hazards; (3) Public health and safety information, including dissemination of such information; (4) Provision of health and safety measures; and (5) Management... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Available assistance. 206.62...
New and incremental FDA black box warnings from 2008 to 2015.
Solotke, Michael T; Dhruva, Sanket S; Downing, Nicholas S; Shah, Nilay D; Ross, Joseph S
2018-02-01
The boxed warning (also known as 'black box warning [BBW]') is one of the strongest drug safety actions that the U.S. Food & Drug Administration (FDA) can implement, and often warns of serious risks. The objective of this study was to comprehensively characterize BBWs issued for drugs after FDA approval. We identified all post-marketing BBWs from January 2008 through June 2015 listed on FDA's MedWatch and Drug Safety Communications websites. We used each drug's prescribing information to classify its BBW as new, major update to a preexisting BBW, or minor update. We then characterized these BBWs with respect to pre-specified BBW-specific and drug-specific features. There were 111 BBWs issued to drugs on the US market, of which 29% (n = 32) were new BBWs, 32% (n = 35) were major updates, and 40% (n = 44) were minor updates. New BBWs and major updates were most commonly issued for death (51%) and cardiovascular risk (27%). The new BBWs and major updates impacted 200 drug formulations over the study period, of which 64% were expected to be used chronically and 58% had available alternatives without a BBW. New BBWs and incremental updates to existing BBWs are frequently added to drug labels after regulatory approval.
Earthquake Early Warning: A Prospective User's Perspective (Invited)
NASA Astrophysics Data System (ADS)
Nishenko, S. P.; Savage, W. U.; Johnson, T.
2009-12-01
With more than 25 million people at risk from high hazard faults in California alone, Earthquake Early Warning (EEW) presents a promising public safety and emergency response tool. EEW represents the real-time end of an earthquake information spectrum which also includes near real-time notifications of earthquake location, magnitude, and shaking levels; as well as geographic information system (GIS)-based products for compiling and visually displaying processed earthquake data such as ShakeMap and ShakeCast. Improvements to and increased multi-national implementation of EEW have stimulated interest in how such information products could be used in the future. Lifeline organizations, consisting of utilities and transportation systems, can use both onsite and regional EEW information as part of their risk management and public safety programs. Regional EEW information can provide improved situational awareness to system operators before automatic system protection devices activate, and allow trained personnel to take precautionary measures. On-site EEW is used for earthquake-actuated automatic gas shutoff valves, triggered garage door openers at fire stations, system controls, etc. While there is no public policy framework for preemptive, precautionary electricity or gas service shutdowns by utilities in the United States, gas shut-off devices are being required at the building owner level by some local governments. In the transportation sector, high-speed rail systems have already demonstrated the ‘proof of concept’ for EEW in several countries, and more EEW systems are being installed. Recently the Bay Area Rapid Transit District (BART) began collaborating with the California Integrated Seismic Network (CISN) and others to assess the potential benefits of EEW technology to mass transit operations and emergency response in the San Francisco Bay region. A key issue in this assessment is that significant earthquakes are likely to occur close to or within the BART system, limiting the time available for an EEW-based response (i.e., slowing or stopping trains). While EEW systems are currently being tested in California, the societal benefits may be even more pronounced in other earthquake-prone parts of the United States. In the central and eastern United States, strong ground motions are felt over significantly larger areas than in California, enabling both a larger area and longer lead times for warnings ahead of the arrival of strong shaking. Because these regions are less resistant to earthquake shaking, such warnings may be even more important for safety and emergency response. However, in many areas a significant increase in the instrumentation density would be required for EEW to become a reality. Although the details of EEW systems are specific to earthquakes, the operation of sensor networks, real-time data analysis, and rapid notification to lifelines is an emerging technology that can be used for real-time detection and early warning of other types of natural and human-caused disasters and emergencies.
2007-05-01
and hand-holds: “The lack of handles on the ladder or adequate hand-holds to help crew members get on/off the cargo bed is unsafe.” (See appendix A...time 1 Why can’t the chief and gunner be in 4-meter circle at same time? Get rid of requirement. There is no safety issue. 2 Encountered no...warning lights. 1 HIMARS is a great piece of equipment all around although it can use a lot of work getting some additional “ bugs ” out and can still
The Influence of Sugar-Sweetened Beverage Health Warning Labels on Parents' Choices.
Roberto, Christina A; Wong, Diandra; Musicus, Aviva; Hammond, David
2016-02-01
US states have introduced bills requiring sugar-sweetened beverages (SSBs) to display health warning labels. This study examined how such labels may influence parents and which labels are most impactful. In this study, 2381 demographically and educationally diverse parents participated in an online survey. Parents were randomly assigned to 1 of 6 conditions: (1) no warning label (control); (2) calorie label; or (3-6) 1 of 4 text versions of a warning label (eg, Safety Warning: Drinking beverages with added sugar[s] contributes to obesity, diabetes, and tooth decay). Parents chose a beverage for their child in a vending machine choice task, rated perceptions of different beverages, and indicated interest in receiving beverage coupons. Regression analyses controlling for frequency of beverage purchases were used to compare the no warning label group, calorie label group, and all warning label groups combined. Significantly fewer parents chose an SSB for their child in the warning label condition (40%) versus the no label (60%) and calorie label conditions (53%). Parents in the warning label condition also chose significantly fewer SSB coupons, believed that SSBs were less healthy for their child, and were less likely to intend to purchase SSBs. All P values <.05 after correcting for multiple comparisons. There were no consistent differences among different versions of the warning labels. Health warning labels on SSBs improved parents' understanding of health harms associated with overconsumption of such beverages and may reduce parents' purchase of SSBs for their children. Copyright © 2016 by the American Academy of Pediatrics.
Research on Occupational Safety, Health Management and Risk Control Technology in Coal Mines.
Zhou, Lu-Jie; Cao, Qing-Gui; Yu, Kai; Wang, Lin-Lin; Wang, Hai-Bin
2018-04-26
This paper studies the occupational safety and health management methods as well as risk control technology associated with the coal mining industry, including daily management of occupational safety and health, identification and assessment of risks, early warning and dynamic monitoring of risks, etc.; also, a B/S mode software (Geting Coal Mine, Jining, Shandong, China), i.e., Coal Mine Occupational Safety and Health Management and Risk Control System, is developed to attain the aforementioned objectives, namely promoting the coal mine occupational safety and health management based on early warning and dynamic monitoring of risks. Furthermore, the practical effectiveness and the associated pattern for applying this software package to coal mining is analyzed. The study indicates that the presently developed coal mine occupational safety and health management and risk control technology and the associated software can support the occupational safety and health management efforts in coal mines in a standardized and effective manner. It can also control the accident risks scientifically and effectively; its effective implementation can further improve the coal mine occupational safety and health management mechanism, and further enhance the risk management approaches. Besides, its implementation indicates that the occupational safety and health management and risk control technology has been established based on a benign cycle involving dynamic feedback and scientific development, which can provide a reliable assurance to the safe operation of coal mines.
Research on Occupational Safety, Health Management and Risk Control Technology in Coal Mines
Zhou, Lu-jie; Cao, Qing-gui; Yu, Kai; Wang, Lin-lin; Wang, Hai-bin
2018-01-01
This paper studies the occupational safety and health management methods as well as risk control technology associated with the coal mining industry, including daily management of occupational safety and health, identification and assessment of risks, early warning and dynamic monitoring of risks, etc.; also, a B/S mode software (Geting Coal Mine, Jining, Shandong, China), i.e., Coal Mine Occupational Safety and Health Management and Risk Control System, is developed to attain the aforementioned objectives, namely promoting the coal mine occupational safety and health management based on early warning and dynamic monitoring of risks. Furthermore, the practical effectiveness and the associated pattern for applying this software package to coal mining is analyzed. The study indicates that the presently developed coal mine occupational safety and health management and risk control technology and the associated software can support the occupational safety and health management efforts in coal mines in a standardized and effective manner. It can also control the accident risks scientifically and effectively; its effective implementation can further improve the coal mine occupational safety and health management mechanism, and further enhance the risk management approaches. Besides, its implementation indicates that the occupational safety and health management and risk control technology has been established based on a benign cycle involving dynamic feedback and scientific development, which can provide a reliable assurance to the safe operation of coal mines. PMID:29701715
Edwards, Brian; Hugman, Bruce; Tobin, Mary; Whalen, Matthew
2012-04-01
Robust, active cooperation, and effective, open communication between all stakeholders is essential for ensuring regulatory compliance and healthcare product safety; avoiding the necessity for whistle-blowing; and, most essentially, meeting the transparency requirements of public trust.The focus here is on what can be done within a healthcare product organization (HPO) to achieve actionable, sustainable policies and practices such as leadership, management, and supervision role-modelling of best practice; ongoing process review and improvements in every department; protection of those who report concerns through robust policies endorsed at Board level throughout an organization to eliminate the fear of retaliation; training in open, non-defensive team-working principles; and mediation structure and process for resolution of differences of opinion or interpretation of contradictory and volatile data.Based on analyses of other safety systems, workplace silence and interpersonal breakdowns are warning signs of defective systems underlying poor compliance and compromising safety. Remedying the situation requires attention to the root causes underlying such symptoms of dysfunction, especially the human factor, i.e. those factors that influence human performance. It is essential that leadership and management listen to employees' concerns about systems and processes, assess them impartially and reward contributions that improve safety.Fundamentally, the safety, transparency, and trustworthiness of HPOs, both commercial and regulatory, can be judged by the extent of the freedom of their staff to 'speak up' when the time is right. This, in turn, consolidates the trust of external stakeholders in the safety of a system and its products. The promotion of 'speaking up' in an organization provides an important safeguard against the risk of poor compliance and the undermining of societal confidence in the safety of healthcare products.
30 CFR 57.14132 - Horns and backup alarms for surface equipment.
Code of Federal Regulations, 2010 CFR
2010-07-01
... NONMETAL MINES Machinery and Equipment Safety Devices and Maintenance Requirements § 57.14132 Horns and backup alarms for surface equipment. (a) Manually-operated horns or other audible warning devices provided on self-propelled mobile equipment as a safety device shall be maintained in a functional...
18 CFR 12.20 - General requirements.
Code of Federal Regulations, 2010 CFR
2010-04-01
..., DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT SAFETY OF WATER POWER PROJECTS AND PROJECT WORKS... local agencies responsible for public health and safety; and (2) Designed to provide early warning to... users, and other persons in the vicinity who might be affected by a project emergency as defined in § 12...
30 CFR 57.4363 - Underground evacuation instruction.
Code of Federal Regulations, 2014 CFR
2014-07-01
... and evacuation plans and procedures and fire warning signals in effect at the mine. (b) Whenever a change is made in escape and evacuation plans and procedures for any area of the mine, all persons... NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire...
30 CFR 57.4363 - Underground evacuation instruction.
Code of Federal Regulations, 2013 CFR
2013-07-01
... and evacuation plans and procedures and fire warning signals in effect at the mine. (b) Whenever a change is made in escape and evacuation plans and procedures for any area of the mine, all persons... NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire...
Fire Safety for Retired Adults: Participant's Coursebook.
ERIC Educational Resources Information Center
Walker (Bonnie) and Associates, Inc., Crofton, MD.
The risk of dying from fire increases substantially among older adults. This document contains a collection of fire safety information for elderly people. Information includes procedures to follow in case of fire and early warning technologies such as smoke alarms. The booklet describes potential sources of fires (smoking, home heating, kitchens,…
30 CFR 57.4363 - Underground evacuation instruction.
Code of Federal Regulations, 2011 CFR
2011-07-01
... and evacuation plans and procedures and fire warning signals in effect at the mine. (b) Whenever a change is made in escape and evacuation plans and procedures for any area of the mine, all persons... NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire...
DOT National Transportation Integrated Search
2015-08-01
This document is the third of a seven volume report that describe the Performance Requirements for the connected vehicle vehicle-to-infrastructure (V2I) safety applications developed for the U.S. Department of Transportation (U.S. DOT). This volume d...
DOT National Transportation Integrated Search
2015-08-01
This document is the second of a seven volume report that describe the Performance Requirements for the connected vehicle vehicle-to-infrastructure (V2I) safety applications developed for the U.S. Department of Transportation (U.S. DOT). This volume ...
Wu, Yina; Abdel-Aty, Mohamed; Ding, Yaoxian; Jia, Bin; Shi, Qi; Yan, Xuedong
2018-07-01
The Type II dilemma zone describes the road segment to a signalized intersection where drivers have difficulties to decide either stop or go at the onset of yellow signal. Such phenomenon can result in an increased crash risk at signalized intersections. Different types of warning systems have been proposed to help drivers make decisions. Although the warning systems help to improve drivers' behavior, they also have several disadvantages such as increasing rear-end crashes or red-light running (RLR) violations. In this study, a new warning system called pavement marking with auxiliary countermeasure (PMAIC) is proposed to reduce the dilemma zone and enhance the traffic safety at signalized intersections. The proposed warning system integrates the pavement marking and flashing yellow system which can provide drivers with better suggestions about stop/go decisions based on their arriving time and speed. In order to evaluate the performance of the proposed warning system, this paper presents a cellular automata (CA) simulation study. The CA simulations are conducted for four different scenarios in total, including the typical intersection without warning system, the intersection with flashing green countermeasure, the intersection with pavement marking, and the intersection with the PMAIC warning system. Before the specific CA simulation analysis, a logistic regression model is calibrated based on field video data to predict drivers' general stop/go decisions. Also, the rules of vehicle movements in the CA models under the influence by different warning systems are proposed. The proxy indicators of rear-end crash and potential RLR violations were estimated and used to evaluate safety levels for the different scenarios. The simulation results showed that the PMAIC countermeasure consistently offered best performance to reduce rear-end crash and RLR violation. Meanwhile, the results indicate that the flashing-green countermeasure could not effectively reduce either rear-end crash risk or RLR violations. Also, it is found that the pavement-marking countermeasure has positive effects on reducing the rear-end risk while it may increase the probability of RLR violation. Lastly, the implementation of the proposed warning system is discussed with the consideration of connected-vehicle technology. It is expected that the dilemma zone issues can be efficiently addressed if the proposed countermeasure can be employed within connected vehicle technology. Copyright © 2017 Elsevier Ltd. All rights reserved.
Chen, Yulong; Irfan, Muhammad; Uchimura, Taro; Zhang, Ke
2018-01-01
Rainfall-induced landslides are one of the most widespread slope instability phenomena posing a serious risk to public safety worldwide so that their temporal prediction is of great interest to establish effective warning systems. The objective of this study is to determine the effectiveness of elastic wave velocities in the surface layer of the slope in monitoring, prediction and early warning of landslide. The small-scale fixed and varied, and large-scale slope model tests were conducted. Analysis of the results has established that the elastic wave velocity continuously decreases in response of moisture content and deformation and there was a distinct surge in the decrease rate of wave velocity when failure was initiated. Based on the preliminary results of this analysis, the method using the change in elastic wave velocity proves superior for landslide early warning and suggests that a warning be issued at switch of wave velocity decrease rate. PMID:29584699
1994-05-01
given prior to issuing or renewing an OF 346? 13. Are operators’ DA Forms 348 reviewed annually for— a. Safety awards? b. Expiration of permits...2. Family safety. Are soldiers instructed to— _ a. Rid basements, closets, and attics of old rugs, papers, mattresses, broken furniture , and...place oily polishing rags or waste in covered metal cans? d. Store paint in tightly closed containers? e. Warn family members to never use gasoline
Oliva, Ana L; La Colla, Noelia S; Arias, Andrés H; Blasina, Gabriela E; Lopez Cazorla, Andrea; Marcovecchio, Jorge E
2017-08-01
The aim of this study is to assess-for the first time-the concentration of the 16 polycyclic aromatic hydrocarbons (PAHs) in the muscle tissues of four fish species (Micropogonias furnieri, Cynoscion guatucupa, Ramnogaster arcuata, and Mustelus schmitti) from Bahía Blanca estuary, Argentina and to evaluate their sources, distribution, and the human health risks implicated. Considering the four species under study, mean total PAH concentrations showed the following decreasing accumulation trend: M. schmitti, R. arcuata, C. guatucupa, and M. furnieri. Low molecular weight PAHs, such as naphthalene and phenanthrene, were generally predominant, displaying properties of PAH mixtures generated from petrogenic pollution. Of the four fish species analyzed, M. furnieri was the only one that did not raise any human consumption warning. In the case of the other species, exceeding values were found above the safety human consumption guidelines. Nevertheless, the screening criteria for carcinogenic PAHs proposed by the USEPA indicated a good quality status for these fish species.
Requirements of a system to reduce car-to-vulnerable road user crashes in urban intersections.
Habibovic, Azra; Davidsson, Johan
2011-07-01
Intersection crashes between cars and vulnerable road users (VRUs), such as pedestrians and bicyclists, often result in injuries and fatalities. Advanced driver assistance systems (ADASs) can prevent, or mitigate, these crashes. To derive functional requirements for such systems, an understanding of the underlying contributing factors and the context in which the crashes occur is essential. The aim of this study is to use microscopic and macroscopic crash data to explore the potential of information and warning providing ADASs, and then to derive functional sensor, collision detection, and human-machine interface (HMI) requirements. The microscopic data were obtained from the European project SafetyNet. Causation charts describing contributing factors for 60 car-to-VRU crashes had been compiled and were then also aggregated using the SafetyNet Accident Causation System (SNACS). The macroscopic data were obtained from the Swedish national crash database, STRADA. A total of 9702 crashes were analyzed. The results show that the most frequent contributing factor to the crashes was the drivers' failure to observe VRUs due to reduced visibility, reduced awareness, and/or insufficient comprehension. An ADAS should therefore help drivers to observe the VRUs in time and to enhance their ability to interpret the development of events in the near future. The system should include a combination of imminent and cautionary collision warnings, with additional support in the form of information about intersection geometry and traffic regulations. The warnings should be deployed via an in-vehicle HMI and according to the likelihood of crash risk. The system should be able to operate under a variety of weather and light conditions. It should have the capacity to support drivers when their view is obstructed by physical objects. To address problems that vehicle-based sensors may face in this regard, the use of cooperative systems is recommended. Copyright © 2011 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Haque, C. Emdad
1995-09-01
Science and technology cannot control entirely the causes of natural hazards. However, by using multifaceted programs to modify the physical and human use systems, the potential losses from disasters can effectively be minized. Predicting, identifying, monitoring, and forecasting extreme meteorological events are the preliminary actions towards mitigating the cyclone-loss potential of coastal inhabitants, but without the successful dissemination of forecasts and relevant information, and without appropriate responses by the potential victims, the loss potential would probably remain the same. This study examines the process through which warning of the impending disastrous cyclone of April 1991 was received by the local communities and disseminated throughout the coastal regions of Bangladesh. It is found that identification of the threatening condition due to atmospheric disturbance, monitoring of the hazard event, and dissemination of the cyclone warning were each very successful. However, due to a number of socioeconomic and cognitive factors, the reactions and responses of coastal inhabitants to the warning were in general passive, resulting in a colossal loss, both at the individual and national level. The study recommends that the hazard mitigation policies should be integrated with national economic development plans and programs. Specifically, it is suggested that, in order to attain its goals, the cyclone warning system should regard the aspects of human response to warnings as a constituent part and accommodate human dimensions in its operational design.
77 FR 35471 - National Environmental Policy Act Implementation
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-13
... designed to promote transportation safety, security, accessibility, communication or operational efficiency... surface treatments or pavement markings, small passenger shelters, railroad warning devices, train control...
NASA Astrophysics Data System (ADS)
Morss, Rebecca E.; Mulder, Kelsey J.; Lazo, Jeffrey K.; Demuth, Julie L.
2016-10-01
This study investigates flash flood forecast and warning communication, interpretation, and decision making, using data from a survey of 418 members of the public in Boulder, Colorado, USA. Respondents to the public survey varied in their perceptions and understandings of flash flood risks in Boulder, and some had misconceptions about flash flood risks, such as the safety of crossing fast-flowing water. About 6% of respondents indicated consistent reversals of US watch-warning alert terminology. However, more in-depth analysis illustrates the multi-dimensional, situationally dependent meanings of flash flood alerts, as well as the importance of evaluating interpretation and use of warning information along with alert terminology. Some public respondents estimated low likelihoods of flash flooding given a flash flood warning; these were associated with lower anticipated likelihood of taking protective action given a warning. Protective action intentions were also lower among respondents who had less trust in flash flood warnings, those who had not made prior preparations for flash flooding, and those who believed themselves to be safer from flash flooding. Additional analysis, using open-ended survey questions about responses to warnings, elucidates the complex, contextual nature of protective decision making during flash flood threats. These findings suggest that warnings can play an important role not only by notifying people that there is a threat and helping motivate people to take protective action, but also by helping people evaluate what actions to take given their situation.
The Influence of Sugar-Sweetened Beverage Warnings
VanEpps, Eric M.; Roberto, Christina A.
2017-01-01
Introduction California, New York, and the cities of San Francisco and Baltimore have introduced bills requiring health-related warning labels for sugar-sweetened beverages. This study measures the extent to which these warning labels influence adolescents’ beliefs and hypothetical choices. Design Participants completed an online survey in which they chose a beverage in a hypothetical vending machine task, rated perceptions of different beverages, and indicated interest in coupons for beverages. Data were collected and analyzed in 2015. Setting/participants A total of 2,202 demographically diverse adolescents aged 12–18 years completed the online survey. Intervention Participants were randomly assigned to one of six conditions: (1) no warning label; (2) calorie label; (3–6) one of four text versions of a warning label (e.g., SAFETY WARNING: Drinking beverages with added sugar(s) contributes to obesity, diabetes, and tooth decay). Main outcome measures Hypothetical choices, perceptions of beverages, interest in coupons, and endorsement of warning label policies were assessed. Results Controlling for frequency of beverage purchases, significantly fewer adolescents chose a sugar-sweetened beverage in three of the four warning label conditions (65%, 63%, and 61%) than in the no label (77%) condition. Adolescents in the four warning label conditions chose fewer sugar-sweetened beverage coupons and believed that sugar-sweetened beverages were less likely to help them lead a healthy life and had more added sugar compared with the no label condition. Conclusions Health-related warning labels on sugar-sweetened beverages improved adolescents’ recognition of the sugar content of such beverages and reduced hypothetical choices to buy sugar-sweetened beverages. PMID:27617366
The Role of Cash Flow in Financial Early Warning of Agricultural Enterprises Based on Logistic Model
NASA Astrophysics Data System (ADS)
Sun, Fengru
2018-01-01
This paper chooses the agricultural listed companies as the research object, compares the financial situation of the enterprise and the theory of financial early warning, combines the financial status of the agricultural listed companies, selects the relevant cash flow indicators, discusses the application of the Logistic financial early warning model in the agricultural listed companies, Agricultural enterprises get better development. Research on financial early warning of agricultural listed companies will help the agricultural listed companies to predict the financial crisis. Financial early warning model is simple to establish, operational and strong, the use of financial early warning model, to help enterprises in the financial crisis before taking rapid and effective measures, which can avoid losses. Help enterprises to discover signs of deterioration of the financial situation in time to maintain the sustainable development of agricultural enterprises. In addition, through the financial early warning model, investors can correctly identify the financial situation of agricultural enterprises, and can evaluate the financial situation of agricultural enterprises and to help investors to invest in scientific and rational, beneficial to investors to analyze the safety of investment. But also help the relevant regulatory agencies to effectively monitor the market and promote the healthy and stable development of the market.
A graph model for preventing railway accidents based on the maximal information coefficient
NASA Astrophysics Data System (ADS)
Shao, Fubo; Li, Keping
2017-01-01
A number of factors influences railway safety. It is an important work to identify important influencing factors and to build the relationship between railway accident and its influencing factors. The maximal information coefficient (MIC) is a good measure of dependence for two-variable relationships which can capture a wide range of associations. Employing MIC, a graph model is proposed for preventing railway accidents which avoids complex mathematical computation. In the graph, nodes denote influencing factors of railway accidents and edges represent dependence of the two linked factors. With the increasing of dependence level, the graph changes from a globally coupled graph to isolated points. Moreover, the important influencing factors are identified from many factors which are the monitor key. Then the relationship between railway accident and important influencing factors is obtained by employing the artificial neural networks. With the relationship, a warning mechanism is built by giving the dangerous zone. If the related factors fall into the dangerous zone in railway operations, the warning level should be raised. The built warning mechanism can prevent railway accidents and can promote railway safety.
NASA Astrophysics Data System (ADS)
Goltz, J. D.
2016-12-01
Although variants of both earthquake early warning and short-term operational earthquake forecasting systems have been implemented or are now being implemented in some regions and nations, they have been slow to gain acceptance within the disciplines that produced them as well as among those for whom they were intended to assist. To accelerate the development and implementation of these technologies will require the cooperation and collaboration of multiple disciplines, some inside and others outside of academia. Seismologists, social scientists, emergency managers, elected officials and key opinion leaders from the media and public must be the participants in this process. Representatives of these groups come from both inside and outside of academia and represent very different organizational cultures, backgrounds and expectations for these systems, sometimes leading to serious disagreements and impediments to further development and implementation. This presentation will focus on examples of the emergence of earthquake early warning and operational earthquake forecasting systems in California, Japan and other regions and document the challenges confronted in the ongoing effort to improve seismic safety.
Zhang, Xiaoliang; Li, Jiali; Liu, Yugang; Zhang, Zutao; Wang, Zhuojun; Luo, Dianyuan; Zhou, Xiang; Zhu, Miankuan; Salman, Waleed; Hu, Guangdi; Wang, Chunbai
2017-03-01
The vigilance of the driver is important for railway safety, despite not being included in the safety management system (SMS) for high-speed train safety. In this paper, a novel fatigue detection system for high-speed train safety based on monitoring train driver vigilance using a wireless wearable electroencephalograph (EEG) is presented. This system is designed to detect whether the driver is drowsiness. The proposed system consists of three main parts: (1) a wireless wearable EEG collection; (2) train driver vigilance detection; and (3) early warning device for train driver. In the first part, an 8-channel wireless wearable brain-computer interface (BCI) device acquires the locomotive driver's brain EEG signal comfortably under high-speed train-driving conditions. The recorded data are transmitted to a personal computer (PC) via Bluetooth. In the second step, a support vector machine (SVM) classification algorithm is implemented to determine the vigilance level using the Fast Fourier transform (FFT) to extract the EEG power spectrum density (PSD). In addition, an early warning device begins to work if fatigue is detected. The simulation and test results demonstrate the feasibility of the proposed fatigue detection system for high-speed train safety.
Engineering design constraints of the lunar surface environment
NASA Technical Reports Server (NTRS)
Morrison, D. A.
1992-01-01
Living and working on the lunar surface will be difficult. Design of habitats, machines, tools, and operational scenarios in order to allow maximum flexibility in human activity will require paying attention to certain constraints imposed by conditions at the surface and the characteristics of lunar material. Primary design drivers for habitat, crew health and safety, and crew equipment are: ionizing radiation, the meteoroid flux, and the thermal environment. Secondary constraints for engineering derive from: the physical and chemical properties of lunar surface materials, rock distributions and regolith thicknesses, topography, electromagnetic properties, and seismicity. Protection from ionizing radiation is essential for crew health and safety. The total dose acquired by a crew member will be the sum of the dose acquired during EVA time (when shielding will be least) plus the dose acquired during time spent in the habitat (when shielding will be maximum). Minimizing the dose acquired in the habitat extends the time allowable for EVA's before a dose limit is reached. Habitat shielding is enabling, and higher precision in predicting secondary fluxes produced in shielding material would be desirable. Means for minimizing dose during a solar flare event while on extended EVA will be essential. Early warning of the onset of flare activity (at least a half-hour is feasible) will dictate the time available to take mitigating steps. Warning capability affects design of rovers (or rover tools) and site layout. Uncertainty in solar flare timing is a design constraint that points to the need for quickly accessible or constructible safe havens.
Engineering design constraints of the lunar surface environment
NASA Astrophysics Data System (ADS)
Morrison, D. A.
1992-02-01
Living and working on the lunar surface will be difficult. Design of habitats, machines, tools, and operational scenarios in order to allow maximum flexibility in human activity will require paying attention to certain constraints imposed by conditions at the surface and the characteristics of lunar material. Primary design drivers for habitat, crew health and safety, and crew equipment are: ionizing radiation, the meteoroid flux, and the thermal environment. Secondary constraints for engineering derive from: the physical and chemical properties of lunar surface materials, rock distributions and regolith thicknesses, topography, electromagnetic properties, and seismicity. Protection from ionizing radiation is essential for crew health and safety. The total dose acquired by a crew member will be the sum of the dose acquired during EVA time (when shielding will be least) plus the dose acquired during time spent in the habitat (when shielding will be maximum). Minimizing the dose acquired in the habitat extends the time allowable for EVA's before a dose limit is reached. Habitat shielding is enabling, and higher precision in predicting secondary fluxes produced in shielding material would be desirable. Means for minimizing dose during a solar flare event while on extended EVA will be essential. Early warning of the onset of flare activity (at least a half-hour is feasible) will dictate the time available to take mitigating steps. Warning capability affects design of rovers (or rover tools) and site layout. Uncertainty in solar flare timing is a design constraint that points to the need for quickly accessible or constructible safe havens.
DOT National Transportation Integrated Search
2014-07-01
Safety is a key concern for the North American railroad industry, particularly for their employees. However, in one particular area there is an identified urgent need for a novel solution that helps protect them better than the current approach: trac...
34 CFR 668.49 - Institutional fire safety policies and fire statistics.
Code of Federal Regulations, 2011 CFR
2011-07-01
... fire. Fire safety system: Any mechanism or system related to the detection of a fire, the warning resulting from a fire, or the control of a fire. This may include sprinkler systems or other fire extinguishing systems, fire detection devices, stand-alone smoke alarms, devices that alert one to the presence...
34 CFR 668.49 - Institutional fire safety policies and fire statistics.
Code of Federal Regulations, 2012 CFR
2012-07-01
... fire. Fire safety system: Any mechanism or system related to the detection of a fire, the warning resulting from a fire, or the control of a fire. This may include sprinkler systems or other fire extinguishing systems, fire detection devices, stand-alone smoke alarms, devices that alert one to the presence...
34 CFR 668.49 - Institutional fire safety policies and fire statistics.
Code of Federal Regulations, 2014 CFR
2014-07-01
... fire. Fire safety system: Any mechanism or system related to the detection of a fire, the warning resulting from a fire, or the control of a fire. This may include sprinkler systems or other fire extinguishing systems, fire detection devices, stand-alone smoke alarms, devices that alert one to the presence...
34 CFR 668.49 - Institutional fire safety policies and fire statistics.
Code of Federal Regulations, 2013 CFR
2013-07-01
... fire. Fire safety system: Any mechanism or system related to the detection of a fire, the warning resulting from a fire, or the control of a fire. This may include sprinkler systems or other fire extinguishing systems, fire detection devices, stand-alone smoke alarms, devices that alert one to the presence...
DOT National Transportation Integrated Search
2015-08-01
This document is the fifth of a seven volume report that describe the Performance Requirements for the connected vehicle vehicle-to-infrastructure (V2I) safety applications developed for the U.S. Department of Transportation (U.S. DOT). This volume d...
DOT National Transportation Integrated Search
2015-08-01
This document is the sixth of a seven volume report that describe the Performance Requirements for the connected vehicle vehicle-to-infrastructure (V2I) safety applications developed for the U.S. Department of Transportation (U.S. DOT). This volume d...
DOT National Transportation Integrated Search
2015-08-01
This document is the fourth of a seven volume report that describe the Performance Requirements for the connected vehicle vehicle-to-infrastructure (V2I) safety applications developed for the U.S. Department of Transportation (U.S. DOT). This volume ...
Light guide technology: using light to enhance safety
NASA Astrophysics Data System (ADS)
Lerner, William S.
2009-05-01
When used to detect extreme temperatures in harsh environments, warning devices have been placed at a distance from the "danger zone" for several reasons. The inability to mix electricity with flammable, caustic, liquid or volatile substances, the limited heat tolerances exhibited by most light sources, and the susceptibility of light sources to damage from vibration, have made the placement of a warning light directly within these harsh environments impossible. This paper describes a system that utilizes a beam of light to provide just such a warning. This system can be used with hard-wired or wireless sensors, side-light illumination, image projection and image transfer. The entire system may be self-contained and portable.
Hammond, David; Thrasher, James; Reid, Jessica L; Driezen, Pete; Boudreau, Christian; Santillán, Edna Arillo
2012-03-01
Pictorial health warnings on cigarette packages are a prominent and effective means of communicating the risks of smoking; however, there is little research on effective types of message content and socio-demographic effects. This study tested message themes and content of pictorial warnings in Mexico. Face-to-face surveys were conducted with 544 adult smokers and 528 youth in Mexico City. Participants were randomized to view 5-7 warnings for two of 15 different health effects. Warnings for each health effect included a text-only warning and pictorial warnings with various themes: "graphic" health effects, "lived experience", symbolic images, and testimonials. Pictorial health warnings were rated as more effective than text-only warnings. Pictorial warnings featuring "graphic" depictions of disease were significantly more effective than symbolic images or experiences of human suffering. Adding testimonial information to warnings increased perceived effectiveness. Adults who were female, older, had lower education, and intended to quit smoking rated warnings as more effective, although the magnitude of these differences was modest. Few interactions were observed between socio-demographics and message theme. Graphic depictions of disease were perceived by youth and adults as the most effective warning theme. Perceptions of warnings were generally similar across socio-demographic groups.
Two NextGen Air Safety Tools: An ADS-B Equipped UAV and a Wake Turbulence Estimator
NASA Astrophysics Data System (ADS)
Handley, Ward A.
Two air safety tools are developed in the context of the FAA's NextGen program. The first tool addresses the alarming increase in the frequency of near-collisions between manned and unmanned aircraft by equipping a common hobby class UAV with an ADS-B transponder that broadcasts its position, speed, heading and unique identification number to all local air traffic. The second tool estimates and outputs the location of dangerous wake vortex corridors in real time based on the ADS-B data collected and processed using a custom software package developed for this project. The TRansponder based Position Information System (TRAPIS) consists of data packet decoders, an aircraft database, Graphical User Interface (GUI) and the wake vortex extension application. Output from TRAPIS can be visualized in Google Earth and alleviates the problem of pilots being left to imagine where invisible wake vortex corridors are based solely on intuition or verbal warnings from ATC. The result of these two tools is the increased situational awareness, and hence safety, of human pilots in the National Airspace System (NAS).
Kalkstein, Adam J; Sheridan, Scott C
2007-10-01
Heat is the leading weather-related killer in the United States. Although previous research suggests that social influences affect human responses to natural disaster warnings, no studies have examined the social impacts of heat or heat warnings on a population. Here, 201 surveys were distributed in Metropolitan Phoenix to determine the social impacts of the heat warning system, or more specifically, to gauge risk perception and warning response. Consistent with previous research, increased risk perception of heat results in increased response to a warning. Different social factors such as sex, race, age, and income all play an important role in determining whether or not people will respond to a warning. In particular, there is a strong sense of perceived risk to the heat among Hispanics which translates to increased response when heat warnings are issued. Based on these findings, suggestions are presented to help improve the Phoenix Heat Warning System.
ADHD Medication Use Following FDA Risk Warnings
Barry, Colleen L.; Martin, Andres; Busch, Susan H.
2013-01-01
Background In 2006, the U.S. Food and Drug Administration (FDA) investigated cardiac and psychiatric risks associated with attention deficit/hyperactivity disorder (ADHD) medication use. Aims of the Study To examine how disclosure of safety risks affected pediatric ADHD use, and to assess news media coverage of the issue to better understand trends in treatment patterns. Methods We used the AHRQ’s Medical Expenditure Panel Survey (MEPS), a nationally representative household panel survey, to calculate unadjusted rates of pediatric ADHD use from 2002 to 2008 overall and by parents’ education. We examined whether children (ages 0 to 20) filled a prescription for any ADHD medication during the calendar year. Next, we used content analysis methods to analyze news coverage of the issue in 10 high-circulation newspapers, the 3 major television networks and a major cable news network in the U.S. We examined 6 measures capturing information conveyed on risk and benefits of ADHD medication use. Results No declines in medication use following FDA safety warnings overall or by parental education level were observed. News media coverage was relatively balanced in its portrayal of the risks and benefits of ADHD medication use by children. Discussion ADHD risk warnings were not associated with large declines in medication use, and balanced news coverage may have contributed to the treatment patterns observed. Self-reported surveys like the MEPS rely on the recall of respondents and may be subject to reporting bias. However, the validity of these data is supported by their consistency with other data on drug use from other sources. Implications for Health Care Provision and Use These findings are in direct contrast to the substantial declines in use observed after pediatric antidepressant risk warnings in the context of a news media environment that emphasized risks over benefits. Implications for Health Policies Our findings are relevant to the ongoing discussion about improving the FDA’s ability to monitor drug safety. Safety warnings occur amid ongoing concern that the agency has insufficient authority and resources to fulfill its mission to protect the public’s health. Efforts to bolster the FDA’s postmarketing surveillance system have the potential to incorporate more data in decision making to allow for earlier detection of health risks. Implications for Further Research Further research is needed to assess whether other treatment changes occurred following risk warnings. For example, it is important to determine whether an increase in cardiac screening prior to medication initiation occurred. Likewise, the FDA advises that children experiencing hallucinations or other psychiatric responses to medication be discontinued from drug treatment. If it is determined that instead of being discontinued from medication treatment, children experiencing hallucinations are put on additional medication (e.g., antipsychotics), additional efforts by the FDA to better inform the public are warranted. PMID:23001280
ADHD medication use following FDA risk warnings.
Barry, Colleen L; Martin, Andres; Busch, Susan H
2012-09-01
In 2006, the U.S. Food and Drug Administration (FDA) investigated cardiac and psychiatric risks associated with attention deficit/hyperactivity disorder (ADHD) medication use. To examine how disclosure of safety risks affected pediatric ADHD use, and to assess news media coverage of the issue to better understand trends in treatment patterns. We used the AHRQ's Medical Expenditure Panel Survey (MEPS), a nationally representative household panel survey, to calculate unadjusted rates of pediatric ADHD use from 2002 to 2008 overall and by parents' education. We examined whether children (ages 0 to 20) filled a prescription for any ADHD medication during the calendar year. Next, we used content analysis methods to analyze news coverage of the issue in 10 high-circulation newspapers, the 3 major television networks and a major cable news network in the U.S. We examined 6 measures capturing information conveyed on risk and benefits of ADHD medication use. No declines in medication use following FDA safety warnings overall or by parental education level were observed. News media coverage was relatively balanced in its portrayal of the risks and benefits of ADHD medication use by children. ADHD risk warnings were not associated with large declines in medication use, and balanced news coverage may have contributed to the treatment patterns observed. Self-reported surveys like the MEPS rely on the recall of respondents and may be subject to reporting bias. However, the validity of these data is supported by their consistency with other data on drug use from other sources. These findings are in direct contrast to the substantial declines in use observed after pediatric antidepressant risk warnings in the context of a news media environment that emphasized risks over benefits. Our findings are relevant to the ongoing discussion about improving the FDA's ability to monitor drug safety. Safety warnings occur amid ongoing concern that the agency has insufficient authority and resources to fulfill its mission to protect the public's health. Efforts to bolster the FDA's post-marketing surveillance system have the potential to incorporate more data in decision making to allow for earlier detection of health risks. Further research is needed to assess whether other treatment changes occurred following risk warnings. For example, it is important to determine whether an increase in cardiac screening prior to medication initiation occurred. Likewise, the FDA advises that children experiencing hallucinations or other psychiatric responses to medication be discontinued from drug treatment. If it is determined that instead of being discontinued from medication treatment, children experiencing hallucinations are put on additional medication (e.g., antipsychotics), additional efforts by the FDA to better inform the public are warranted.
The new weight-loss drugs, lorcaserin and phentermine-topiramate: slim pickings?
Woloshin, Steven; Schwartz, Lisa M
2014-04-01
In 2012, the US Food and Drug Administration approved 2 drugs for long-term weight loss: lorcaserin hydrochloride (Belviq; Eisai Inc) and phentermine-topiramate (Qysmia; Vivus Inc). The approvals were based on 1-year trials showing that on top of recommendations to follow a calorie-restricted diet and to increase exercise, patients randomized to either drug lost more weight than patients randomized to placebo (3% [95% CI, 3%-4%] more weight lost with lorcaserin; 7% [95% CI, 3%-4%] more with phentermine /topiramate). The drugs have been associated with serious harms: Both drugs' labels include warnings about memory, attention, or language problems and depression; for lorcaserin, the label also warns of valvular heart disease and euphoria; and for phentermine-topiramate, the label warns of metabolic acidosis, increased heart rate, anxiety, insomnia, and elevated creatinine levels. Neither medication is marketed in Europe because of safety concerns. The manufacturer withdrew its application for lorcaserin in Europe after the European Medicines Agency (EMA) said approval was unlikely, and the EMA rejected phentermine-topiramate. In the United States, the required postmarketing safety trials are behind schedule. Until there is more convincing evidence about the cardiovascular safety of these drugs, physicians and patients should approach them cautiously. Patients who do not lose at least 5% of their body weight within 12 weeks of starting to take either drug should stop taking it, as stated in the prescribing information.
... the safety of using pennyroyal leaf as a tea. Special precautions & warnings: Pennyroyal is LIKELY UNSAFE for ... life-long kidney and liver damage. Pennyroyal leaf tea seems to be able to start menstruation, which ...
Waveguide Modulator for Interference Tolerant Functional Near Infrared Spectrometer (fNIRS)
NASA Technical Reports Server (NTRS)
Walton, Joanne; Tin, Padetha; Mackey, Jeffrey
2017-01-01
Many crew-related errors in aviation and astronautics are caused by hazardous cognitive states including overstress, disengagement, high fatigue and ineffective crew coordination. Safety can be improved by monitoring and predicting these cognitive states in a non-intrusive manner and designing mitigation strategies. Measuring hemoglobin concentration changes in the brain with functional Near Infrared Spectroscopy is a promising technique for monitoring cognitive state and optimizing human performance during both space and aviation operations. A compact, wearable fNIRS system would provide an innovative early warning system during long duration missions to detect and prevent vigilance decrements in pilots and astronauts. This effort focused on developing a waveguide modulator for use in a fNIRS system.
Sefton, Gerri; Lane, Steven; Killen, Roger; Black, Stuart; Lyon, Max; Ampah, Pearl; Sproule, Cathryn; Loren-Gosling, Dominic; Richards, Caitlin; Spinty, Jean; Holloway, Colette; Davies, Coral; Wilson, April; Chean, Chung Shen; Carter, Bernie; Carrol, E.D.
2017-01-01
Pediatric Early Warning Scores are advocated to assist health professionals to identify early signs of serious illness or deterioration in hospitalized children. Scores are derived from the weighting applied to recorded vital signs and clinical observations reflecting deviation from a predetermined “norm.” Higher aggregate scores trigger an escalation in care aimed at preventing critical deterioration. Process errors made while recording these data, including plotting or calculation errors, have the potential to impede the reliability of the score. To test this hypothesis, we conducted a controlled study of documentation using five clinical vignettes. We measured the accuracy of vital sign recording, score calculation, and time taken to complete documentation using a handheld electronic physiological surveillance system, VitalPAC Pediatric, compared with traditional paper-based charts. We explored the user acceptability of both methods using a Web-based survey. Twenty-three staff participated in the controlled study. The electronic physiological surveillance system improved the accuracy of vital sign recording, 98.5% versus 85.6%, P < .02, Pediatric Early Warning Score calculation, 94.6% versus 55.7%, P < .02, and saved time, 68 versus 98 seconds, compared with paper-based documentation, P < .002. Twenty-nine staff completed the Web-based survey. They perceived that the electronic physiological surveillance system offered safety benefits by reducing human error while providing instant visibility of recorded data to the entire clinical team. PMID:27832032
2016-01-01
Warning beacons are critical for the safety of transportation, construction, and utility workers. These devices need to produce sufficient luminous intensity to be visible without creating glare to drivers. Published standards for the photometric performance of warning beacons do not address their performance in conditions of reduced visibility such as fog. Under such conditions light emitted in directions other than toward approaching drivers can create scattered light that makes workers and other hazards less visible. Simulations of visibility of hazards under varying conditions of fog density, forward vehicle lighting, warning beacon luminous intensity, and intensity distribution were performed to assess their impacts on visual performance by drivers. Each of these factors can influence the ability of drivers to detect and identify workers and hazards along the roadway in work zones. Based on the results, it would be reasonable to specify maximum limits on the luminous intensity of warning beacons in directions that are unlikely to be seen by drivers along the roadway, limits which are not included in published performance specifications. PMID:27314058
Hammond, David; Thrasher, James; Reid, Jessica L.; Driezen, Pete; Boudreau, Christian; Santillan, Edna Arillo
2015-01-01
Purpose Pictorial health warnings on cigarette packages are a prominent and effective means of communicating the risks of smoking; however, there is little research on effective types of message content and socio-demographic effects. This study tested message themes and content of pictorial warnings in Mexico. Methods Face-to-face surveys were conducted with 544 adult smokers and 528 youth in Mexico City. Participants were randomized to view 5–7 warnings for two of 15 different health effects. Warnings for each health effect included a text-only warning and pictorial warnings with various themes: “graphic” health effects, “lived experience”, symbolic images, and testimonials. Results Pictorial health warnings were rated as more effective than text-only warnings. Pictorial warnings featuring “graphic” depictions of disease were significantly more effective than symbolic images or experiences of human suffering. Adding testimonial information to warnings increased perceived effectiveness. Adults who were female, older, had lower education, and intended to quit smoking rated warnings as more effective, although the magnitude of these differences was modest. Few interactions were observed between socio-demographics and message theme. Conclusions Graphic depictions of disease were perceived by youth and adults as the most effective warning theme. Perceptions of warnings were generally similar across socio-demographic groups. PMID:22362058
... Data SAFETY Floods Tsunami Beach Hazards Wildfire Cold Tornadoes Fog Air Quality Heat Hurricanes Lightning Safe Boating ... Winter Weather Forecasts River Flooding Latest Warnings Thunderstorm/Tornado Outlook Hurricanes Fire Weather Outlooks UV Alerts Drought ...
Research and technology at the Kennedy Space Center
NASA Technical Reports Server (NTRS)
1983-01-01
Cryogenic engineering, hypergolic engineering, hazardous warning, structures and mechanics, computer sciences, communications, meteorology, technology applications, safety engineering, materials analysis, biomedicine, and engineering management and training aids research are reviewed.
Hospital outpatients' responses to taking medications with driving warnings.
Smyth, T; Sheehan, M; Siskind, V
2013-01-01
The study investigates the knowledge, intentions, and driving behavior of persons prescribed medications that display a warning about driving. It also examines their confidence that they can self-assess possible impairment, as is required by the Australian labeling system. We surveyed 358 outpatients in an Australian public hospital pharmacy, representing a well-advised group taking a range of medications including those displaying a warning label about driving. A brief telephone follow-up survey was conducted with a subgroup of the participants. The sample had a median age of 53.2 years and was 53 percent male. Nearly three quarters (73.2%) had taken a potentially impairing class of medication and more than half (56.1%) had taken more than one such medication in the past 12 months. Knowledge of the potentially impairing effects of medication was relatively high for most items; however, participants underestimated the possibility of increased impairment from exceeding the prescribed dose and at commencing treatment. Participants' responses to the safety implications of taking drugs with the highest level of warning varied. Around two thirds (62.8%) indicated that they would consult a health practitioner for advice and around half would modify their driving in some way. However, one fifth (20.9%) would drive when the traffic was thought to be less heavy and over a third (37.7%) would modify their medication regime so that they could drive. The findings from the follow-up survey of a subsample taking target drugs at the time of the first interview were also of concern. Only just over half (51%) recalled seeing the warning label on their medications and, of this group, three quarters (78%) reported following the warning label advice. These findings indicated that there remains a large proportion of people who either did not notice or did not consider the warning when deciding whether to drive. There was a very high level of confidence in this group that they could determine whether they were personally affected by the medication, which may be a problem from a safety perspective. This study involved persons who should have had a very high level of knowledge and awareness of medication warning labeling. Even in this group there was a lack of informed response to potential impairment. A review of the Australian warning system and wider dissemination of information on medication treatment effects would be useful. Clarifying the importance of potential risk in the general community context is recommended for consideration and further research.
Casting a global safety net--a framework for food safety in the age of globalization.
Chyau, James
2009-01-01
In mid-March 2007, Ontario-based Menu Foods Inc. started recalling its "cuts and gravy" style pet food, after receiving information that pets that had eaten the product had fallen ill. Within a week, the company was inundated with complaints and expressions of concern from about 200,000 of its customers. The Food and Drug Administration (FDA) determined in late March 2007 that the most likely culprit in the illness, and in some cases death of the pet animals, was contaminated wheat gluten, a vegetable protein imported from China. One of the FDA identified contaminants was an industrial chemical called melamine. Reports of widespread adulteration of animal feed with melamine in China raised concern of similar contamination in the human food supply. In response, on April 27, 2007, FDA announced the detention of all vegetable proteins imported from China, whether for animal or for human consumption. But, FDA's action came too late. On May 1, 2007, officials from FDA and the U.S. Department of Agriculture (USDA) indicated that between 2.5 to 3 million people in the United States had consumed chickens that had been fed with contaminated vegetable proteins imported from China. The 2007 pet food recall incident provided an ominous early warning that, unless the international community can come up with a better food safety mechanism, more such food contamination disasters could happen in the future.
Ruscio, Daniele; Ciceri, Maria Rita; Biassoni, Federica
2015-04-01
Brake Reaction Time (BRT) is an important parameter for road safety. Previous research has shown that drivers' expectations can impact RT when facing hazardous situations, but driving with advanced driver assistance systems, can change the way BRT are considered. The interaction with a collision warning system can help faster more efficient responses, but at the same time can require a monitoring task and evaluation process that may lead to automation complacency. The aims of the present study are to test in a real-life setting whether automation compliancy can be generated by a collision warning system and what component of expectancy can impact the different tasks involved in an assisted BRT process. More specifically four component of expectancy were investigated: presence/absence of anticipatory information, previous direct experience, reliability of the device, and predictability of the hazard determined by repeated use of the warning system. Results supply indication on perception time and mental elaboration of the collision warning system alerts. In particular reliable warning quickened the decision making process, misleading warnings generated automation complacency slowing visual search for hazard detection, lack of directed experienced slowed the overall response while unexpected failure of the device lead to inattentional blindness and potential pseudo-accidents with surprise obstacle intrusion. Copyright © 2015 Elsevier Ltd. All rights reserved.
Ride-on lawnmowers warnings: slope measurements and safety-by-separation.
Karnes, Edward W; Leonard, S David; Lenorovitz, David R
2012-01-01
Various single-rider open vehicles, such as lawnmowers, are susceptible to overturning on slopes that are too steep for them. Warnings have included separation from the vehicles and avoiding slopes that are too steep. A recommended maximum slope is commonly 15 degrees. However, many individuals cannot evaluate slopes just by sight. Some mower manufacturers have warned about too steep slopes and have provided slope gauges for users to determine the slopes in natural settings. This article evaluated the usefulness of such gauges for users who might be expected to need to evaluate slopes and the efficacy of a separation procedure for avoiding injuries. It was concluded that neither of these were likely to be successful and suggestions are made for alternative approaches.
Mintzes, Barbara; Morgan, Steve; Wright, James M
2009-05-27
Direct-to-consumer advertising (DTCA) of prescription drugs is illegal in Canada as a health protection measure, but is permitted in the United States. However, in 2000, Canadian policy was changed to allow 'reminder' advertising of prescription drugs. This is a form of advertising that states the brand name without health claims. 'Reminder' advertising is prohibited in the US for drugs that have 'black box' warnings of serious risks. This study examines spending on DTCA in Canada from 1995 to 2006, 12 years spanning this policy shift. We ask how annual per capita spending compares to that in the US, and whether drugs with Canadian or US regulatory safety warnings are advertised to the Canadian public in reminder advertising. Prescription drug advertising spending data were extracted from a data set on health sector spending in Canada obtained from a market research company, TNS Media Inc. Spending was adjusted for inflation and compared with US spending. Inflation-adjusted spending on branded DTCA in Canada grew from under CAD$2 million per year before 1999 to over $22 million in 2006. The major growth was in broadcast advertising, accounting for 83% of spending in 2006. US annual per capita spending was on average 24 times Canadian levels. Celebrex (celecoxib), which has a US black box and was subject to three safety advisories in Canada, was the most heavily advertised drug on Canadian television in 2005 and 2006. Of 8 brands with >$500,000 spending, which together accounted for 59% of branded DTCA in all media, 6 were subject to Canadian safety advisories, and 4 had US black box warnings. Branded 'reminder' advertising has grown rapidly in Canada since 2000, mainly due to a growth in television advertising. Although DTCA spending per capita is much lower in Canada than in the US, there is no evidence of safer content or product choice; many heavily-advertised drugs in Canada have been subject to safety advisories. For governments searching for compromise solutions to industry pressure for expanded advertising, Canada's experience stands as a stark warning.
Mintzes, Barbara; Morgan, Steve; Wright, James M.
2009-01-01
Background Direct-to-consumer advertising (DTCA) of prescription drugs is illegal in Canada as a health protection measure, but is permitted in the United States. However, in 2000, Canadian policy was changed to allow ‘reminder’ advertising of prescription drugs. This is a form of advertising that states the brand name without health claims. ‘Reminder’ advertising is prohibited in the US for drugs that have ‘black box’ warnings of serious risks. This study examines spending on DTCA in Canada from 1995 to 2006, 12 years spanning this policy shift. We ask how annual per capita spending compares to that in the US, and whether drugs with Canadian or US regulatory safety warnings are advertised to the Canadian public in reminder advertising. Methodology/Principal Findings Prescription drug advertising spending data were extracted from a data set on health sector spending in Canada obtained from a market research company, TNS Media Inc. Spending was adjusted for inflation and compared with US spending. Inflation-adjusted spending on branded DTCA in Canada grew from under CAD$2 million per year before 1999 to over $22 million in 2006. The major growth was in broadcast advertising, accounting for 83% of spending in 2006. US annual per capita spending was on average 24 times Canadian levels. Celebrex (celecoxib), which has a US black box and was subject to three safety advisories in Canada, was the most heavily advertised drug on Canadian television in 2005 and 2006. Of 8 brands with >$500,000 spending, which together accounted for 59% of branded DTCA in all media, 6 were subject to Canadian safety advisories, and 4 had US black box warnings. Conclusions/Significance Branded ‘reminder’ advertising has grown rapidly in Canada since 2000, mainly due to a growth in television advertising. Although DTCA spending per capita is much lower in Canada than in the US, there is no evidence of safer content or product choice; many heavily-advertised drugs in Canada have been subject to safety advisories. For governments searching for compromise solutions to industry pressure for expanded advertising, Canada's experience stands as a stark warning. PMID:19479084
Development of a New Departure Aversion Standard for Light Aircraft
NASA Technical Reports Server (NTRS)
Borer, Nicholas K.
2017-01-01
The Federal Aviation Administration (FAA) and European Aviation Safety Agency (EASA) have recently established new light aircraft certification rules that introduce significant changes to the current regulations. The changes include moving from prescriptive design requirements to performance-based standards, transferring many of the acceptable means of compliance out of the rules and into consensus standards. In addition, the FAA/EASA rules change the performance requirements associated with some of the more salient safety issues regarding light aircraft. One significant change is the elimination of spin recovery demonstration. The new rules now call for enhanced stall warning and aircraft handling characteristics that demonstrate resistance to inadvertent departure from controlled flight. The means of compliance with these changes in a safe, cost-effective manner is a challenging problem. This paper discusses existing approaches to reducing the likelihood of departure from controlled flight and introduces a new approach, dubbed Departure Aversion, which allows applicants to tailor the amount of departure resistance, stall warning, and enhanced safety equipment to meet the new proposed rules. The Departure Aversion approach gives applicants the freedom to select the most cost-effective portfolio for their design, while meeting the safety intent of the new rules, by ensuring that any combination of the selected approaches will be at a higher equivalent level of safety than today's status quo.
Zhang, Xiaoliang; Li, Jiali; Liu, Yugang; Zhang, Zutao; Wang, Zhuojun; Luo, Dianyuan; Zhou, Xiang; Zhu, Miankuan; Salman, Waleed; Hu, Guangdi; Wang, Chunbai
2017-01-01
The vigilance of the driver is important for railway safety, despite not being included in the safety management system (SMS) for high-speed train safety. In this paper, a novel fatigue detection system for high-speed train safety based on monitoring train driver vigilance using a wireless wearable electroencephalograph (EEG) is presented. This system is designed to detect whether the driver is drowsiness. The proposed system consists of three main parts: (1) a wireless wearable EEG collection; (2) train driver vigilance detection; and (3) early warning device for train driver. In the first part, an 8-channel wireless wearable brain-computer interface (BCI) device acquires the locomotive driver’s brain EEG signal comfortably under high-speed train-driving conditions. The recorded data are transmitted to a personal computer (PC) via Bluetooth. In the second step, a support vector machine (SVM) classification algorithm is implemented to determine the vigilance level using the Fast Fourier transform (FFT) to extract the EEG power spectrum density (PSD). In addition, an early warning device begins to work if fatigue is detected. The simulation and test results demonstrate the feasibility of the proposed fatigue detection system for high-speed train safety. PMID:28257073
How Safe and Innovative Are First-in-Class Drugs Approved by Health Canada: A Cohort Study
2016-01-01
Introduction: First-in-class drugs use a unique mechanism of action. This study assessed the therapeutic innovativeness and safety of these drugs approved by Health Canada from 1997–2012. Methods: A list of new drugs was compiled and a database from the Food and Drug Administration was used to determine first-in-class status. Post-market safety warnings and drugs withdrawn for safety reasons were identified from the MedEffect Canada website. Therapeutic innovation evaluations came from the Patented Medicine Prices Review Board (PMPRB) and Prescrire International. The proportion of first-in-class drugs that were innovative was compared to the proportion of non-first-in-class drugs that were innovative. Kaplan–Meier survival curves assessed safety. Results: In all, 462 drugs were approved by Health Canada during the period under study. Among these, 345 were evaluated by PMPRB and/or Prescrire, and first-in-class data were available for 292. Ninety-eight of the 292 were first-in-class and 16 were innovative compared to 9 of 194 drugs that were not-first-in-class. There was no difference in safety between the two groups. Discussion: Overall, the benefit-to-harm ratio of first-in-class drugs, as measured by post-market safety warnings/withdrawals, is better than those that were not-first-in-class. PMID:28032825
Study of Water Pollution Early Warning Framework Based on Internet of Things
NASA Astrophysics Data System (ADS)
Chengfang, H.; Xiao, X.; Dingtao, S.; Bo, C.; Xiongfei, W.
2016-06-01
In recent years, with the increasing world environmental pollution happening, sudden water pollution incident has become more and more frequently in China. It has posed a serious threat to water safety of the people living in the water source area. Conventional water pollution monitoring method is manual periodic testing, it maybe miss the best time to find that pollution incident. This paper proposes a water pollution warning framework to change this state. On the basis of the Internet of things, we uses automatic water quality monitoring technology to realize monitoring. We calculate the monitoring data with water pollution model to judge whether the water pollution incident is happen or not. Water pollution warning framework is divided into three layers: terminal as the sensing layer, it with the deployment of the automatic water quality pollution monitoring sensor. The middle layer is the transfer network layer, data information implementation is based on GPRS wireless network transmission. The upper one is the application layer. With these application systems, early warning information of water pollution will realize the high-speed transmission between grassroots units and superior units. The paper finally gives an example that applying this pollution warning framework to water quality monitoring of Beijing, China, it greatly improves the speed of the pollution warning responding of Beijing.
The Common Alerting Protocol (CAP) adaption in National Early Warning Alerting Systems of China
NASA Astrophysics Data System (ADS)
Li, Chao
2017-04-01
The Common Alerting Protocol (CAP) [1] is an XML-based data format for exchanging public warnings and emergencies between alerting technologies. In China, from local communities to entire nations, there was a patchwork of specialized hazard public alerting systems. And each system was often designed just for certain emergency situations and for certain communications media. Application took place in the NEWAS (National Early Warning Alerting Systems) [2]project where CAP serves as central message to integrate all kind of hazard situations, including the natural calamity, accident disaster, public health emergency , social safety etc. Officially operated on May 2015, NEWAS now has completed docking work with 14 departments including civil administration, safety supervision, forestry, land, water conservancy, earthquake, traffic, meteorology, agriculture, tourism, food and drug supervision, public security and oceanic administration. Thus, several items in CAP has been modified, redefined and extended according to the various grading standards and publishing strategies, as well as the characteristics of Chinese Geocoding. NEWAS successfully delivers information to end users through 4 levels (i.e. State, province, prefecture and county) structure and by various means. [1] CAP, http://www.oasis-emergency.org/cap [2] http://www.12379.cn/
Vlassov, Vasiliy; Mansfield, Peter; Lexchin, Joel; Vlassova, Anna
2001-01-01
Objective To examine pharmaceutical advertisements in medical journals for their adequacy of information. Methods We selected a convenience sample of 5 major Russian medical journals covering different fields of medicine and different types of publications. We evaluated all the ads in all the issues of the selected journals published during 1998. We counted the number of appearances of trade, chemical, and generic names; indication and contraindication; pharmacologic group; safety warnings; and references. Counts in all categories were aggregated for each advertiser. Results There were 397 placements of 207 distinct advertisements. Only 154 placements (40%) mentioned the generic name, 177 (45%) mentioned any indication, 42 (11%) mentioned safety warnings and contraindications, 21 (5%) warned about drug interactions, and 8 (2%) provided references. The 6 companies responsible for the most ads on average provided less information than the other companies. Conclusions Almost none of the drug ads published in Russian medical journals provide the basic information required for appropriate prescribing. This is despite the fact that in Russia, ads that omit essential information and that could lead consumers to misunderstandings about an advertised product are illegal. The arrival of drug advertising in Russia has brought little information and has been potentially damaging. PMID:11381003
Cohen, Pieter A; Bloszies, Clayton; Yee, Caleb; Gerona, Roy
2016-01-01
The amphetamine isomer β-methylphenylethylamine (BMPEA) was first synthesized in the early 1930s, but its efficacy and safety in humans has not been studied. Recently, the United States Food and Drug Administration (FDA) detected BMPEA in dietary supplements labelled as containing Acacia rigidula. Over a year after the FDA reported its findings, we analyzed Acacia rigidula dietary supplements to determine if BMPEA had been removed. Supplements were analyzed using liquid chromatography-quadrupole time-of-flight mass spectrometry. Diluted methanolic extract from each supplement was run three times and each data set obtained was analyzed using Agilent MassHunter Qualitative Analysis. The presence of BMPEA was confirmed by accurate mass, retention time and mass spectra match against a reference standard. Quantification of BMPEA was determined using an eight-point calibration curve of spiked standard to a matrix blank. Twenty-one brands of Acacia rigidula supplements were analyzed. More than half (11/21; 52.4%) of the Acacia rigidula supplement brands contained BMPEA. The stimulant was present at quantities such that consumers following recommended maximum daily servings would consume a maximum of 93.7 mg of BMPEA per day. Consumers of Acacia rigidula supplements may be exposed to pharmacological dosages of an amphetamine isomer that lacks evidence of safety in humans. The FDA should immediately warn consumers about BMPEA and take aggressive enforcement action to eliminate BMPEA in dietary supplements. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.
RhIG for the treatment of immune thrombocytopenia: consensus and controversy
Despotovic, Jenny M.; Lambert, Michele P.; Herman, Jay H.; Gernsheimer, Terry B.; McCrae, Keith R.; Tarantino, Michael D.; Bussel, James B.
2012-01-01
Anti-D immune globulin (RhIG) is a front-line option in North America for the treatment of immune thrombocytopenia (ITP) in children and adults. Recently, addition of a Food and Drug Administration-mandated black box warning highlighted the risks of intravascular hemolysis, renal failure, and disseminated intravascular coagulation after anti-D infusion, prompting concern within the medical community regarding its use. A working group convened in response to this warning to prepare a consensus document regarding the safety of RhIG because there has been no increased incidence of adverse events since the initial discovery of these reactions many years ago. The efficacy of anti-D is well documented and only briefly reviewed. The estimated incidence and proposed mechanisms for the rare, major treatment-related complications are discussed, and signal detection data associated with heightened risk of acute hemolytic reactions are presented. The importance of considering host factors, given the rarity of severe reactions, is emphasized. Safety profiles of parallel treatment options are reviewed. The working group consensus is that RhIG has comparable safety and efficacy to other front-line agents for the treatment of children and adults with ITP. Safety may be further improved by careful patient selection. PMID:21981825
46 CFR 183.220 - General safety provisions.
Code of Federal Regulations, 2013 CFR
2013-10-01
... equipment and circuits must be clearly marked and identified. (e) Any cabinet, panel, box, or other enclosure containing more than one source of power must be fitted with a sign warning persons of this...
46 CFR 183.220 - General safety provisions.
Code of Federal Regulations, 2012 CFR
2012-10-01
... equipment and circuits must be clearly marked and identified. (e) Any cabinet, panel, box, or other enclosure containing more than one source of power must be fitted with a sign warning persons of this...
46 CFR 183.220 - General safety provisions.
Code of Federal Regulations, 2014 CFR
2014-10-01
... equipment and circuits must be clearly marked and identified. (e) Any cabinet, panel, box, or other enclosure containing more than one source of power must be fitted with a sign warning persons of this...
ERIC Educational Resources Information Center
Dorn, Michael
1998-01-01
Presents expert advice on keeping violations of school trespassing from escalating into worse violations of school safety. Discusses the use of trespass-warning statements, identifying areas of danger, and whether police officers in schools are the solution. (GR)
24 CFR 3282.410 - Contents of notice.
Code of Federal Regulations, 2010 CFR
2010-04-01
... home is repaired. (d) An evaluation of the risk to manufactured home occupants' safety and the... that warning would be, and any signs which the owner might see, hear, smell, or feel which might...
TravTek evaluation Orlando test network study
DOT National Transportation Integrated Search
1996-03-01
THE INVEHICLE SAFETY ADVISORY AND WARNING SYSTEM (IVSAWS) IS A FEDERAL HIGHWAY ADMINISTRATION EFFORT TO DEVELOP A NATIONWIDE VEHICULAR INFORMATION SYSTEM THAT PROVIDES DRIVERS WITH ADVANCE, SUPPLEMENTAL NOTIFICATION OF DANGEROUS ROAD CONDITIONS USING...
Winter Weather Frequently Asked Questions
... Hot Weather Tips Warning Signs and Symptoms FAQs Social Media How to Stay Cool Missouri Cooling Centers Extreme ... PSAs for Disasters Resources for Emergency Health Professionals Social Media Health and Safety Concerns for All Disasters Animals ...
Believability of Cigar Warning Labels Among Adolescents.
Kowitt, Sarah D; Jarman, Kristen; Ranney, Leah M; Goldstein, Adam O
2017-03-01
Despite high rates of cigar use among youth, little information exists about how cigar warnings are received by youth. We examined believability of different cigar warning messages with different sources among adolescents in a national phone survey. Adolescents (aged 13-17 years) in the US (N = 1,125; total response rate, 66%) were randomized to receive one of three health messages ("cigar smoking can cause cancers of the mouth and throat, even if you do not inhale," "cigar smoking can cause lung cancer and heart disease," and "cigars are not a safe alternative to cigarettes") and one of four warning sources (Food and Drug Administration, Surgeon General, Centers for Disease Control and Prevention, and no source). Believability was assessed with "how believable is this warning," and responses were dichotomized for "not at all or somewhat" versus "very." Weighted logistic regression results indicated that most youth found the cigar warnings very believable (60.5%). Messages about mouth and throat cancer (regardless of inhalation) and the safety of cigars in comparison to cigarettes were rated as significantly less believable than messages about lung cancer and heart disease related to cigars. There were no significant differences by source or other demographics. However, youth susceptible to using cigarettes were less likely to report the cigar warnings to be very believable. The messages of cigar warning labels are not viewed as equally believable among adolescents. Future studies should examine how youth process messages about health effects of cigars and the impact of different cigar warnings on youth experimentation with and use of cigars. Copyright © 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.
Read, Gemma J M; Salmon, Paul M; Lenné, Michael G
2013-09-01
Collisions at rail level crossings are an international safety concern and have been the subject of considerable research effort. Modern human factors practice advocates a systems approach to investigating safety issues in complex systems. This paper describes the results of a structured review of the level crossing literature to determine the extent to which a systems approach has been applied. The measures used to determine if previous research was underpinned by a systems approach were: the type of analysis method utilised, the number of component relationships considered, the number of user groups considered, the number of system levels considered and the type of model described in the research. None of research reviewed was found to be consistent with a systems approach. It is recommended that further research utilise a systems approach to the study of the level crossing system to enable the identification of effective design improvements. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.
Timing of new black box warnings and withdrawals for prescription medications.
Lasser, Karen E; Allen, Paul D; Woolhandler, Steffie J; Himmelstein, David U; Wolfe, Sidney M; Bor, David H
2002-05-01
Recently approved drugs may be more likely to have unrecognized adverse drug reactions (ADRs) than established drugs, but no recent studies have examined how frequently postmarketing surveillance identifies important ADRs. To determine the frequency and timing of discovery of new ADRs described in black box warnings or necessitating withdrawal of the drug from the market. Examination of the Physicians' Desk Reference for all new chemical entities approved by the US Food and Drug Administration between 1975 and 1999, and all drugs withdrawn from the market between 1975 and 2000 (with or without a prior black box warning). Frequency of and time to a new black box warning or drug withdrawal. A total of 548 new chemical entities were approved in 1975-1999; 56 (10.2%) acquired a new black box warning or were withdrawn. Forty-five drugs (8.2%) acquired 1 or more black box warnings and 16 (2.9%) were withdrawn from the market. In Kaplan-Meier analyses, the estimated probability of acquiring a new black box warning or being withdrawn from the market over 25 years was 20%. Eighty-one major changes to drug labeling in the Physicians' Desk Reference occurred including the addition of 1 or more black box warnings per drug, or drug withdrawal. In Kaplan-Meier analyses, half of these changes occurred within 7 years of drug introduction; half of the withdrawals occurred within 2 years. Serious ADRs commonly emerge after Food and Drug Administration approval. The safety of new agents cannot be known with certainty until a drug has been on the market for many years.
Believability of Cigar Warning Labels among Adolescents
Kowitt, Sarah D.; Jarman, Kristen; Ranney, Leah M.; Goldstein, Adam O.
2016-01-01
Purpose Despite high rates of cigar use among youth, little information exists about how cigar warnings are received by youth. We examined believability of different cigar warning messages with different sources among adolescents in a national phone survey. Methods Adolescents (age 13-17) in the US (N = 1,125; total response rate, 66%) were randomized to receive one of three health messages (“cigar smoking can cause cancers of the mouth and throat, even if you do not inhale”, “cigar smoking can cause lung cancer and heart disease”, “cigars are not a safe alternative to cigarettes”) and one of four warning sources (FDA, Surgeon General, CDC, no source). Believability was assessed with “how believable is this warning” and responses were dichotomized for “not at all or somewhat” vs. “very”. Results Weighted logistic regression results indicated that most youth found the cigar warnings very believable (60.5%). Messages about mouth and throat cancer (regardless of inhalation) and the safety of cigars in comparison to cigarettes were rated as significantly less believable than messages about lung cancer and heart disease related to cigars. There were no significant differences by source or other demographics. However, youth susceptible to using cigarettes were less likely to report the cigar warnings to be very believable. Conclusions The messages of cigar warning labels are not viewed as equally believable among adolescents. Future studies should examine how youth process messages about health effects of cigars and the impact of different cigar warnings on youth experimentation with and use of cigars. PMID:27965023
Code of Federal Regulations, 2010 CFR
2010-04-01
... immediate container label with a statement directed to pharmacists not to remove the label or (ii) by including in the package a printed warning with instructions to pharmacists to place the warning on the...
Code of Federal Regulations, 2013 CFR
2013-04-01
... immediate container label with a statement directed to pharmacists not to remove the label or (ii) by including in the package a printed warning with instructions to pharmacists to place the warning on the...
Code of Federal Regulations, 2014 CFR
2014-04-01
... immediate container label with a statement directed to pharmacists not to remove the label or (ii) by including in the package a printed warning with instructions to pharmacists to place the warning on the...
Code of Federal Regulations, 2011 CFR
2011-04-01
... immediate container label with a statement directed to pharmacists not to remove the label or (ii) by including in the package a printed warning with instructions to pharmacists to place the warning on the...
Code of Federal Regulations, 2012 CFR
2012-04-01
... immediate container label with a statement directed to pharmacists not to remove the label or (ii) by including in the package a printed warning with instructions to pharmacists to place the warning on the...
Practice-based evidence: profiling the safety of cilostazol by text-mining of clinical notes.
Leeper, Nicholas J; Bauer-Mehren, Anna; Iyer, Srinivasan V; Lependu, Paea; Olson, Cliff; Shah, Nigam H
2013-01-01
Peripheral arterial disease (PAD) is a growing problem with few available therapies. Cilostazol is the only FDA-approved medication with a class I indication for intermittent claudication, but carries a black box warning due to concerns for increased cardiovascular mortality. To assess the validity of this black box warning, we employed a novel text-analytics pipeline to quantify the adverse events associated with Cilostazol use in a clinical setting, including patients with congestive heart failure (CHF). We analyzed the electronic medical records of 1.8 million subjects from the Stanford clinical data warehouse spanning 18 years using a novel text-mining/statistical analytics pipeline. We identified 232 PAD patients taking Cilostazol and created a control group of 1,160 PAD patients not taking this drug using 1:5 propensity-score matching. Over a mean follow up of 4.2 years, we observed no association between Cilostazol use and any major adverse cardiovascular event including stroke (OR = 1.13, CI [0.82, 1.55]), myocardial infarction (OR = 1.00, CI [0.71, 1.39]), or death (OR = 0.86, CI [0.63, 1.18]). Cilostazol was not associated with an increase in any arrhythmic complication. We also identified a subset of CHF patients who were prescribed Cilostazol despite its black box warning, and found that it did not increase mortality in this high-risk group of patients. This proof of principle study shows the potential of text-analytics to mine clinical data warehouses to uncover 'natural experiments' such as the use of Cilostazol in CHF patients. We envision this method will have broad applications for examining difficult to test clinical hypotheses and to aid in post-marketing drug safety surveillance. Moreover, our observations argue for a prospective study to examine the validity of a drug safety warning that may be unnecessarily limiting the use of an efficacious therapy.
Practice-Based Evidence: Profiling the Safety of Cilostazol by Text-Mining of Clinical Notes
Iyer, Srinivasan V.; LePendu, Paea; Olson, Cliff; Shah, Nigam H.
2013-01-01
Background Peripheral arterial disease (PAD) is a growing problem with few available therapies. Cilostazol is the only FDA-approved medication with a class I indication for intermittent claudication, but carries a black box warning due to concerns for increased cardiovascular mortality. To assess the validity of this black box warning, we employed a novel text-analytics pipeline to quantify the adverse events associated with Cilostazol use in a clinical setting, including patients with congestive heart failure (CHF). Methods and Results We analyzed the electronic medical records of 1.8 million subjects from the Stanford clinical data warehouse spanning 18 years using a novel text-mining/statistical analytics pipeline. We identified 232 PAD patients taking Cilostazol and created a control group of 1,160 PAD patients not taking this drug using 1∶5 propensity-score matching. Over a mean follow up of 4.2 years, we observed no association between Cilostazol use and any major adverse cardiovascular event including stroke (OR = 1.13, CI [0.82, 1.55]), myocardial infarction (OR = 1.00, CI [0.71, 1.39]), or death (OR = 0.86, CI [0.63, 1.18]). Cilostazol was not associated with an increase in any arrhythmic complication. We also identified a subset of CHF patients who were prescribed Cilostazol despite its black box warning, and found that it did not increase mortality in this high-risk group of patients. Conclusions This proof of principle study shows the potential of text-analytics to mine clinical data warehouses to uncover ‘natural experiments’ such as the use of Cilostazol in CHF patients. We envision this method will have broad applications for examining difficult to test clinical hypotheses and to aid in post-marketing drug safety surveillance. Moreover, our observations argue for a prospective study to examine the validity of a drug safety warning that may be unnecessarily limiting the use of an efficacious therapy. PMID:23717437
Robust Kalman filter design for predictive wind shear detection
NASA Technical Reports Server (NTRS)
Stratton, Alexander D.; Stengel, Robert F.
1991-01-01
Severe, low-altitude wind shear is a threat to aviation safety. Airborne sensors under development measure the radial component of wind along a line directly in front of an aircraft. In this paper, optimal estimation theory is used to define a detection algorithm to warn of hazardous wind shear from these sensors. To achieve robustness, a wind shear detection algorithm must distinguish threatening wind shear from less hazardous gustiness, despite variations in wind shear structure. This paper presents statistical analysis methods to refine wind shear detection algorithm robustness. Computational methods predict the ability to warn of severe wind shear and avoid false warning. Comparative capability of the detection algorithm as a function of its design parameters is determined, identifying designs that provide robust detection of severe wind shear.
Shiloh, Ariel L; Lominadze, George; Gong, Michelle N; Savel, Richard H
2016-02-01
As a global effort toward improving patient safety, a specific area of focus has been the early recognition and rapid intervention in deteriorating ward patients. This focus on "failure to rescue" has led to the construction of early warning/track-and-trigger systems. In this review article, we present a description of the data behind the creation and implementation of such systems, including multiple algorithms and strategies for deployment. Additionally, the strengths and weaknesses of the various systems and their evaluation in the literature are emphasized. Despite the limitations of the current literature, the potential benefit of these early warning/track-and-trigger systems to improve patient outcomes remains significant. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
[New international initiatives to create systems of effective risk prediction and food safety].
Efimochkinal, N R; Bagryantseva, E C; Dupouy, E C; Khotimchenko, S A; Permyakov, E V; Sheveleva, S A; Arnautov, O V
2016-01-01
Ensuring food safety is one of the most important problems that is directly related to health protection of the population. The problem is particularly relevant on aglobalscale because ofincreasingnumberoffood-borne diseases andimportance of the health consequence early detection. In accordance with the position of the Codex Alimentarius Commission, food safety concept also includes quality. In this case, creation of the national, supranational and international early warning systems related to the food safety, designed with the purpose to prevent or minimize risks on different stages of the food value chain in various countries, regions and climate zones specific to national nutrition and lifestyle in different groups of population, gains particular importance. The article describes the principles and working examples of international, supranational and national food safety early warning systems. Great importance is given to the hazards of microbial origin - emergent pathogens. Example of the rapid reaction to the appearance of cases, related to the melanin presence in infant formula, are presented. Analysis of the current food safety and quality control system in Russian Federation shows that main improvements are mostly related to the development of the efficient monitoring, diagnostics and rapid alert procedures forfood safety on interregional and international levels that will allow to estimate real contamination of food with the most dangerous pathogens, chemical and biological contaminants, and the development of the electronic database and scientifically proved algorithms for food safety and quality management for targeted prevention activities against existing and emerging microbiological and other etiology risks, and public health protection.
16 CFR 1117.5 - Information that must be reported and to whom.
Code of Federal Regulations, 2010 CFR
2010-01-01
... SAFETY ACT REGULATIONS REPORTING OF CHOKING INCIDENTS INVOLVING MARBLES, SMALL BALLS, LATEX BALLOONS AND... (including any labeling and warnings), a description of the marble, small ball, latex balloon or other small...
Millimeter wave radar for automobile crash avoidance systems
NASA Astrophysics Data System (ADS)
Huguenin, G. Richard
1994-08-01
Low cost, millimeter wave, forward looking radar sensors for applications in Autonomous Collision Warning and Autonomous Intelligent Cruise Control systems will be described. These safety related systems promise the largest payoff in preventing highway crashes.
49 CFR 234.109 - Recordkeeping.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
49 CFR 234.109 - Recordkeeping.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
49 CFR 234.106 - Partial activation.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
49 CFR 234.101 - Employee notification rules.
Code of Federal Regulations, 2014 CFR
2014-10-01
....101 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at...
49 CFR 234.107 - False activation.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
49 CFR 234.105 - Activation failure.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
49 CFR 234.101 - Employee notification rules.
Code of Federal Regulations, 2012 CFR
2012-10-01
....101 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at...
49 CFR 234.107 - False activation.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
49 CFR 234.107 - False activation.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
49 CFR 234.106 - Partial activation.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
49 CFR 234.101 - Employee notification rules.
Code of Federal Regulations, 2013 CFR
2013-10-01
....101 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at...
49 CFR 234.105 - Activation failure.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
49 CFR 234.109 - Recordkeeping.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
49 CFR 234.106 - Partial activation.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
49 CFR 234.105 - Activation failure.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SAFETY, INCLUDING SIGNAL SYSTEMS, STATE ACTION PLANS, AND EMERGENCY NOTIFICATION SYSTEMS Response to Credible Reports of Warning System Malfunction at Highway-Rail...
Shetty, Yashashri C; Saiyed, Aafreen A
2015-05-01
The US Food and Drug Administration (FDA) issues warning letters to all research stakeholders if unacceptable deficiencies are found during site visits. Warning letters issued by the FDA between January 2011 and December 2012 to clinical investigators and institutional review boards (IRBs) were reviewed for various violation themes and compared to similar studies in the past. Warning letters issued to sponsors between January 2005 and December 2012 were analysed for the first time for a specific set of violations using descriptive statistics. Failure to protect subject safety and to report adverse events to IRBs was found to be significant compared to prior studies for clinical investigators, while failure to follow standard operating procedures and maintain documentation was noted as significant in warning letters to IRBs. Failure to maintain minutes of meeting and to follow written procedures for continuing review were new substantial violations in warning letters issued to IRBs. Forty-six warning letters were issued to sponsors, the most common violations being failure to follow a monitoring schedule (58.69%), failure to obtain investigator agreement (34.78%), failure to secure investigators' compliance (30.43%), and failure to maintain data records and ship documents to investigators (30.43%). Appropriate methods for handling clinical trial procedural violations should be developed and implemented worldwide. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
Measuring driver responses at railway level crossings.
Tey, Li-Sian; Ferreira, Luis; Wallace, Angela
2011-11-01
Railway level crossings are amongst the most complex of road safety control systems, due to the conflicts between road vehicles and rail infrastructure, trains and train operations. Driver behaviour at railway crossings is the major collision factor. The main objective of the present paper was to evaluate the existing conventional warning devices in relation to driver behaviour. The common conventional warning devices in Australia are a stop sign (passive), flashing lights and a half boom-barrier with flashing lights (active). The data were collected using two approaches, namely: field video recordings at selected sites and a driving simulator in a laboratory. This paper describes and compares the driver response results from both the field survey and the driving simulator. The conclusion drawn is that different types of warning systems resulted in varying driver responses at crossings. The results showed that on average driver responses to passive crossings were poor when compared to active ones. The field results were consistent with the simulator results for the existing conventional warning devices and hence they may be used to calibrate the simulator for further evaluation of alternative warning systems. Copyright © 2011 Elsevier Ltd. All rights reserved.
Human Factors In the Joint Typhoon Warning Center Watch Floor
2012-11-01
Report 3. DATES COVERED (From-To) 01-10-2010 – 30-03-2011 4. TITLE AND SUBTITLE Human Factors in the Joint Typhoon Warning Center Watch Floor...between users’ information requirements and interpretation process and the JTWC’s forecast fields. The language of TCCOR definitions provides one (of...direction error is less than 90°, predicting a position 10 nautical miles (nmi) too close to the current position produces a lower FTE than
Modeling Pilot Behavior for Assessing Integrated Alert and Notification Systems on Flight Decks
NASA Technical Reports Server (NTRS)
Cover, Mathew; Schnell, Thomas
2010-01-01
Numerous new flight deck configurations for caution, warning, and alerts can be conceived; yet testing them with human-in-the-Ioop experiments to evaluate each one would not be practical. New sensors, instruments, and displays are being put into cockpits every day and this is particularly true as we enter the dawn of the Next Generation Air Transportation System (NextGen). By modeling pilot behavior in a computer simulation, an unlimited number of unique caution, warning, and alert configurations can be evaluated 24/7 by a computer. These computer simulations can then identify the most promising candidate formats to further evaluate in higher fidelity, but more costly, Human-in-the-Ioop (HITL) simulations. Evaluations using batch simulations with human performance models saves time, money, and enables a broader consideration of possible caution, warning, and alerting configurations for future flight decks.
Comparison of Human Response against Earthquake and Tsunami
NASA Astrophysics Data System (ADS)
Arikawa, T.; Güler, H. G.; Yalciner, A. C.
2017-12-01
The evacuation response against the earthquake and tsunamis is very important for the reduction of human damages against tsunami. But it is very difficult to predict the human behavior after shaking of the earthquake. The purpose of this research is to clarify the difference of the human response after the earthquake shock in the difference countries and to consider the relation between the response and the safety feeling, knowledge and education. For the objective of this paper, the questionnaire survey was conducted after the 21st July 2017 Gokova earthquake and tsunami. Then, consider the difference of the human behavior by comparison of that in 2015 Chilean earthquake and tsunami and 2011 Japan earthquake and tsunami. The seismic intensity of the survey points was almost 6 to 7. The contents of the questions include the feeling of shaking, recalling of the tsunami, the behavior after shock and so on. The questionnaire was conducted for more than 20 20 people in 10 areas. The results are the following; 1) Most people felt that it was a strong shake not to stand, 2) All of the questionnaires did not recall the tsunami, 3) Depending on the area, they felt that after the earthquake the beach was safer than being at home. 4) After they saw the sea drawing, they thought that a tsunami would come and ran away. Fig. 1 shows the comparison of the evacuation rate within 10 minutes in 2011 Japan, 2015 Chile and 2017 Turkey.. From the education point of view, education for tsunami is not done much in Turkey. From the protection facilities point of view, the high sea walls are constructed only in Japan. From the warning alert point of view, there is no warning system against tsunamis in the Mediterranean Sea. As a result of this survey, the importance of tsunami education is shown, and evacuation tends to be delayed if dependency on facilities and alarms is too high.
Forecasting infectious disease emergence subject to seasonal forcing.
Miller, Paige B; O'Dea, Eamon B; Rohani, Pejman; Drake, John M
2017-09-06
Despite high vaccination coverage, many childhood infections pose a growing threat to human populations. Accurate disease forecasting would be of tremendous value to public health. Forecasting disease emergence using early warning signals (EWS) is possible in non-seasonal models of infectious diseases. Here, we assessed whether EWS also anticipate disease emergence in seasonal models. We simulated the dynamics of an immunizing infectious pathogen approaching the tipping point to disease endemicity. To explore the effect of seasonality on the reliability of early warning statistics, we varied the amplitude of fluctuations around the average transmission. We proposed and analyzed two new early warning signals based on the wavelet spectrum. We measured the reliability of the early warning signals depending on the strength of their trend preceding the tipping point and then calculated the Area Under the Curve (AUC) statistic. Early warning signals were reliable when disease transmission was subject to seasonal forcing. Wavelet-based early warning signals were as reliable as other conventional early warning signals. We found that removing seasonal trends, prior to analysis, did not improve early warning statistics uniformly. Early warning signals anticipate the onset of critical transitions for infectious diseases which are subject to seasonal forcing. Wavelet-based early warning statistics can also be used to forecast infectious disease.
Response time effects of alerting tone and semantic context for synthesized voice cockpit warnings
NASA Technical Reports Server (NTRS)
Simpson, C. A.; Williams, D. H.
1980-01-01
Some handbooks and human factors design guides have recommended that a voice warning should be preceded by a tone to attract attention to the warning. As far as can be determined from a search of the literature, no experimental evidence supporting this exists. A fixed-base simulator flown by airline pilots was used to test the hypothesis that the total 'system-time' to respond to a synthesized voice cockpit warning would be longer when the message was preceded by a tone because the voice itself was expected to perform both the alerting and the information transfer functions. The simulation included realistic ATC radio voice communications, synthesized engine noise, cockpit conversation, and realistic flight routes. The effect of a tone before a voice warning was to lengthen response time; that is, responses were slower with an alerting tone. Lengthening the voice warning with another work, however, did not increase response time.
NASA Technical Reports Server (NTRS)
1974-01-01
System design and performance of the Skylab Airlock Module and Payload Shroud are presented for the communication and caution and warning systems. Crew station and storage, crew trainers, experiments, ground support equipment, and system support activities are also reviewed. Other areas documented include the reliability and safety programs, test philosophy, engineering project management, and mission operations support.
Code of Federal Regulations, 2013 CFR
2013-04-01
... requirements for the display of health warnings on cigarette packages and in advertisements for cigarettes. FDA... violation of this part as it applies to the display of health warnings in an advertisement for cigarettes if... AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) TOBACCO PRODUCTS...
Safety interventions on the labor and delivery unit.
Kacmar, Rachel M
2017-06-01
The present review highlights recent advances in efforts to improve patient safety on labor and delivery units and well tolerated care for pregnant patients in general. Recent studies in obstetric patient safety have a broad focus but repetitive themes for interdisciplinary training include: simulating critical events, having open multidisciplinary communication, frequent reviews of cases of maternal morbidity, and implementing maternal early warning systems. The National Partnership for Maternal Safety is also active in promoting care bundles across many topics on maternal safety. A culture of safety is the goal for all obstetric units. Achieving that ideal requires multidisciplinary collaboration, frequent reassessment for areas of improvement, and a culture of openness to change when improvement opportunities arise.
Communications and radar-supported transportation operations and planning : final report.
DOT National Transportation Integrated Search
2017-03-01
This project designs a conceptual framework to harness and mature wireless technology to improve : transportation safety, with a focus on frontal collision warning/collision avoidance (CW/CA) systems. The : framework identifies components of the tech...
Intersection collision warning system
DOT National Transportation Integrated Search
1999-04-01
Safety at unsignalized intersections is a major concern. Intersection collisions are one of the most common types of crash, and in the United States, they account for nearly 2 million accidents and 6,700 fatalities every year. However, a fully signal...
EU-US standards harmonization task group report : testing for ITS security.
DOT National Transportation Integrated Search
1996-03-01
THE INVEHICLE SAFETY ADVISORY AND WARNING SYSTEM (IVSAWS) IS A FEDERAL HIGHWAY ADMINISTRATION EFFORT TO DEVELOP' A NATIONWIDE VEHICULAR INFORMATION SYSTEM THAT PROVIDES DRIVERS WITH ADVANCE, SUPPLEMENTAL NOTIFICATION OF DANGEROUS ROAD CONDITIONS USIN...
Dilemma zone protection on high-speed arterials.
DOT National Transportation Integrated Search
2014-12-01
Driver behavior within the dilemma zone can be a major safety concern at high-speed signalized intersections, especially : for heavy trucks. The Nebraska Department of Roads (NDOR) has developed and implemented an Actuated Advance : Warning (AAW) dil...
Timing issues for traffic signals interconnected with highway-railroad grade crossings.
DOT National Transportation Integrated Search
2013-02-01
The coordination of highway-railroad grade crossing warning signals with nearby traffic signals is of vital : importance due to potential safety consequences. Interconnections between traffic signals in close : proximity to railroad crossings provide...
A Lightning Safety Primer for Camps.
ERIC Educational Resources Information Center
Attarian, Aram
1992-01-01
Provides the following information about lightning, which is necessary for camp administrators and staff: (1) warning signs of lightning; (2) dangers of lightning; (3) types of lightning injuries; (4) prevention of lightning injury; and (5) helpful training tips. (KS)
NASA Astrophysics Data System (ADS)
Park, Joon-Sang; Lee, Uichin; Oh, Soon Young; Gerla, Mario; Lun, Desmond Siumen; Ro, Won Woo; Park, Joonseok
Vehicular ad hoc networks (VANET) aims to enhance vehicle navigation safety by providing an early warning system: any chance of accidents is informed through the wireless communication between vehicles. For the warning system to work, it is crucial that safety messages be reliably delivered to the target vehicles in a timely manner and thus reliable and timely data dissemination service is the key building block of VANET. Data mulling technique combined with three strategies, network codeing, erasure coding and repetition coding, is proposed for the reliable and timely data dissemination service. Particularly, vehicles in the opposite direction on a highway are exploited as data mules, mobile nodes physically delivering data to destinations, to overcome intermittent network connectivity cause by sparse vehicle traffic. Using analytic models, we show that in such a highway data mulling scenario the network coding based strategy outperforms erasure coding and repetition based strategies.
Forward Collision Warning: Clues to Optimal Timing of Advisory Warnings
Aksan, Nazan; Sager, Lauren; Hacker, Sarah; Marini, Robert; Dawson, Jeffrey; Anderson, Steven; Rizzo, Matthew
2016-01-01
We examined the effectiveness of a heads-up Forward Collision Warning (FCW) system in 39 younger to middle aged drivers (25-50, mean = 35 years) and 37 older drivers (66-87, mean = 77 years). The warnings were implemented in a fixed based, immersive, 180 degree forward field of view simulator. The FCW included a visual advisory component consisting of a red horizontal bar which flashed in the center screen of the simulator that was triggered at time-to-collision (TTC) 4 seconds. The bar roughly overlapped the rear bumper of the lead vehicle, just below the driver's line-of-sight. A sustained auditory tone (~80 dB) was activated at TTC=2 to alert the driver to an imminent collision. Hence, the warning system differed from the industry standard in significant ways. 95% Confidence intervals for the safety gains ranged from −.03 to .19 seconds in terms of average correction time across several activations. Older and younger adults did not differ in terms of safety gains. Closer inspection of data revealed that younger to middle aged drivers were already braking (42%) on a larger proportion of FCW activations than older drivers (26%), p < .001. Conversely, older drivers were still accelerating (38%) on a larger proportion of FCW activations than younger to middle aged drivers (23%) at the time FCW was activated, p < .009. There were no differences in the proportion of activations when drivers were coasting at the time FCW was activated, p = .240. Furthermore, large individual differences in basic visual, motor, and cognitive function predicted the tendency to brake prior to FCW activation. Those who tended to be better functioning in each of these domains were more likely to be already braking prior to FCW activation at the fixed threshold of TTC=4. These findings suggest optimal timing for advisory alerts for forward events may need to be larger than TTC=4. PMID:27648455
A trial of retrofitted advisory collision avoidance technology in government fleet vehicles.
Thompson, James P; Mackenzie, Jamie R R; Dutschke, Jeffrey K; Baldock, Matthew R J; Raftery, Simon J; Wall, John
2018-06-01
In-vehicle collision avoidance technology (CAT) has the potential to prevent crash involvement. In 2015, Transport for New South Wales undertook a trial of a Mobileye 560 CAT system that was installed in 34 government fleet vehicles for a period of seven months. The system provided headway monitoring, lane departure, forward collision and pedestrian collision warnings, using audio and visual alerts. The purpose of the trial was to determine whether the technology could change the driving behaviour of fleet vehicle drivers and improve their safety. The evaluation consisted of three components: (1) analysis of objective data to examine effects of the technology on driving behaviour, (2) analysis of video footage taken from a sample of the vehicles to examine driving circumstances that trigger headway monitoring and forward collision warnings, and (3) a survey completed by 122 of the 199 individuals who drove the trial vehicles to examine experiences with, and attitudes to, the technology. Analysis of the objective data found that the system resulted in changes in behaviour with increased headway and improved lane keeping, but that these improvements dissipated once the warning alerts were switched off. Therefore, the system is capable of altering behaviour but only when it is actively providing alerts. In-vehicle video footage revealed that over a quarter of forward collision warnings were false alarms, in which a warning event was triggered despite there being no vehicle travelling ahead. The surveyed drivers recognised that the system could improve safety but most did not wish to use it themselves as they found it to be distracting and felt that it would not prevent them from having a crash. The results demonstrate that collision avoidance technology can improve driving behaviour but drivers may need to be educated about the potential benefits for their driving in order to accept the technology. Copyright © 2018 Elsevier Ltd. All rights reserved.
The Global Emergency Observation and Warning System
NASA Technical Reports Server (NTRS)
Bukley, Angelia P.; Mulqueen, John A.
1994-01-01
Based on an extensive characterization of natural hazards, and an evaluation of their impacts on humanity, a set of functional technical requirements for a global warning and relief system was developed. Since no technological breakthroughs are required to implement a global system capable of performing the functions required to provide sufficient information for prevention, preparedness, warning, and relief from natural disaster effects, a system is proposed which would combine the elements of remote sensing, data processing, information distribution, and communications support on a global scale for disaster mitigation.
Developing effective warning systems: Ongoing research at Ruapehu volcano, New Zealand
NASA Astrophysics Data System (ADS)
Leonard, Graham S.; Johnston, David M.; Paton, Douglas; Christianson, Amy; Becker, Julia; Keys, Harry
2008-05-01
PurposeThis paper examines the unique challenges to volcanic risk management associated with having a ski area on an active volcano. Using a series of simulated eruption/lahar events at Ruapehu volcano, New Zealand, as a context, a model of risk management that integrates warning system design and technology, risk perceptions and the human response is explored. Principal resultsDespite increases in the observed audibility and comprehension of the warning message, recall of public education content, and people's awareness of volcanic risk, a persistent minority of the public continued to demonstrate only moderate awareness of the correct actions to take during a warning and failed to respond effectively. A relationship between level of staff competence and correct public response allowed the level of public response to be used to identify residual risk and additional staff training needs. The quality of staff awareness, action and decision-making has emerged as a critical factor, from detailed staff and public interviews and from exercise observations. Staff actions are especially important for mobilising correct public response at Ruapehu ski areas due to the transient nature of the visitor population. Introduction of education material and staff training strategies that included the development of emergency decision-making competencies improved knowledge of correct actions, and increased the proportion of people moving out of harm's way during blind tests. Major conclusionsWarning effectiveness is a function of more than good hazard knowledge and the generation and notification of an early warning message. For warning systems to be effective, these factors must be complemented by accurate knowledge of risk and risk management actions. By combining the Ruapehu findings with those of other warning system studies in New Zealand, and internationally, a practical five-step model for effective early warning systems is discussed. These steps must be based upon sound and regularly updated underpinning science and be tied to formal effectiveness evaluation, which is fed back into system improvements. The model presented emphasises human considerations, the development of which arguably require even more effort than the hardware components of early warning systems.
DOT National Transportation Integrated Search
1996-03-01
THE INVEHICLE SAFETY ADVISORY AND WARNING SYSTEM (IVSAWS) IS A FEDERAL HIGHWAY ADMINISTRATION EFFORT TO DEVELOP A NATIONWIDE VEHICULAR INFORMATION SYSTEM THAT PROVIDES DRIVERS WITH ADVANCE, SUPPLEMENTAL NOTIFICATION OF DANGEROUS ROAD CONDITIONS USING...
Speed limit recommendation in vicinity of signalized, high-speed intersection.
DOT National Transportation Integrated Search
2012-04-01
We evaluated the traffic operations and safety effects of 5 mph and 10 mph speed limit reductions in the vicinity of highspeed, : signalized intersections with advance warning flashers (AWF). Traffic operational effects of the reduced speed : limits ...
What You Need to Know When the Power Goes Out Unexpectedly
... Hot Weather Tips Warning Signs and Symptoms FAQs Social Media How to Stay Cool Missouri Cooling Centers Extreme ... PSAs for Disasters Resources for Emergency Health Professionals Social Media Health and Safety Concerns for All Disasters Animals ...
47 CFR 80.1063 - Special requirements for INMARSAT-E EPIRB stations.
Code of Federal Regulations, 2011 CFR
2011-10-01
... standards contained in IEC 61097-5 Ed. 1.0, titled “Global maritime and distress safety system (GMDSS)—Part... written warning that failure to register the radiobeacon could delay rescue services in an emergency. (e...
47 CFR 80.1063 - Special requirements for INMARSAT-E EPIRB stations.
Code of Federal Regulations, 2010 CFR
2010-10-01
... standards contained in IEC 61097-5 Ed. 1.0, titled “Global maritime and distress safety system (GMDSS)—Part... written warning that failure to register the radiobeacon could delay rescue services in an emergency. (e...
40 CFR 156.66 - Child hazard warning.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Child hazard warning. 156.66 Section... LABELING REQUIREMENTS FOR PESTICIDES AND DEVICES Human Hazard and Precautionary Statements § 156.66 Child... Out of Reach of Children.” That statement, or any alternative statement approved by EPA, must appear...
40 CFR 156.66 - Child hazard warning.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Child hazard warning. 156.66 Section... LABELING REQUIREMENTS FOR PESTICIDES AND DEVICES Human Hazard and Precautionary Statements § 156.66 Child... Out of Reach of Children.” That statement, or any alternative statement approved by EPA, must appear...
40 CFR 156.66 - Child hazard warning.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Child hazard warning. 156.66 Section... LABELING REQUIREMENTS FOR PESTICIDES AND DEVICES Human Hazard and Precautionary Statements § 156.66 Child... Out of Reach of Children.” That statement, or any alternative statement approved by EPA, must appear...
40 CFR 156.66 - Child hazard warning.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Child hazard warning. 156.66 Section... LABELING REQUIREMENTS FOR PESTICIDES AND DEVICES Human Hazard and Precautionary Statements § 156.66 Child... Out of Reach of Children.” That statement, or any alternative statement approved by EPA, must appear...
40 CFR 156.66 - Child hazard warning.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Child hazard warning. 156.66 Section... LABELING REQUIREMENTS FOR PESTICIDES AND DEVICES Human Hazard and Precautionary Statements § 156.66 Child... Out of Reach of Children.” That statement, or any alternative statement approved by EPA, must appear...
21 CFR 890.5575 - Powered external limb overload warning device.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Powered external limb overload warning device. 890.5575 Section 890.5575 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Therapeutic Devices § 890...
21 CFR 890.5575 - Powered external limb overload warning device.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Powered external limb overload warning device. 890.5575 Section 890.5575 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Therapeutic Devices § 890...
21 CFR 890.5575 - Powered external limb overload warning device.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Powered external limb overload warning device. 890.5575 Section 890.5575 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Therapeutic Devices § 890...
21 CFR 890.5575 - Powered external limb overload warning device.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Powered external limb overload warning device. 890.5575 Section 890.5575 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Therapeutic Devices § 890...
21 CFR 890.5575 - Powered external limb overload warning device.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Powered external limb overload warning device. 890.5575 Section 890.5575 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Therapeutic Devices § 890...
Depicting the Suffering of Others
ERIC Educational Resources Information Center
Kostouros, Patricia
2016-01-01
This article offers a discussion about the depiction of traumatic materials to postsecondary human service students. Presently there is an on-going debate about trigger warnings and whether trigger warnings are necessary prior to engaging in materials that depict the suffering of others. Perhaps after depicting graphic images some teachers have…
21 CFR 740.17 - Foaming detergent bath products.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Foaming detergent bath products. 740.17 Section 740.17 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.17 Foaming detergent bath products...
21 CFR 740.17 - Foaming detergent bath products.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Foaming detergent bath products. 740.17 Section 740.17 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.17 Foaming detergent bath products...
21 CFR 740.17 - Foaming detergent bath products.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Foaming detergent bath products. 740.17 Section 740.17 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.17 Foaming detergent bath products...
21 CFR 740.17 - Foaming detergent bath products.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Foaming detergent bath products. 740.17 Section 740.17 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.17 Foaming detergent bath products...
21 CFR 740.17 - Foaming detergent bath products.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Foaming detergent bath products. 740.17 Section 740.17 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.17 Foaming detergent bath products...
Sheynin, Jony; Beck, Kevin D; Servatius, Richard J; Myers, Catherine E
2014-01-01
While avoidance behavior is often an adaptive strategy, exaggerated avoidance can be detrimental and result in the development of psychopathologies, such as anxiety disorders. A large animal literature shows that the acquisition and extinction of avoidance behavior in rodents depends on individual differences (e.g., sex, strain) and might be modulated by the presence of environmental cues. However, there is a dearth of such reports in human literature, mainly due to the lack of adequate experimental paradigms. In the current study, we employed a computer-based task, where participants control a spaceship and attempt to gain points by shooting an enemy spaceship that appears on the screen. Warning signals predict on-screen aversive events; the participants can learn a protective response to escape or avoid these events. This task has been recently used to reveal facilitated acquisition of avoidance behavior in individuals with anxiety vulnerability due to female sex or inhibited personality. Here, we extended the task to include an extinction phase, and tested the effect of signals that appeared during "safe" periods. Healthy young adults (n = 122) were randomly assigned to a testing condition with or without such signals. Results showed that the addition of safety signals during the acquisition phase impaired acquisition (in females) and facilitated extinction of the avoidance behavior. We also replicated our recent finding of an association between female sex and longer avoidance duration and further showed that females continued to demonstrate more avoidance behavior even on extinction trials when the aversive events no longer occurred. This study is the first to show sex differences on the acquisition and extinction of human avoidance behavior and to demonstrate the role of safety signals in such behavior, highlighting the potential relevance of safety signals for cognitive therapies that focus on extinction learning to treat anxiety symptoms.
Sheynin, Jony; Beck, Kevin D.; Servatius, Richard J.; Myers, Catherine E.
2014-01-01
While avoidance behavior is often an adaptive strategy, exaggerated avoidance can be detrimental and result in the development of psychopathologies, such as anxiety disorders. A large animal literature shows that the acquisition and extinction of avoidance behavior in rodents depends on individual differences (e.g., sex, strain) and might be modulated by the presence of environmental cues. However, there is a dearth of such reports in human literature, mainly due to the lack of adequate experimental paradigms. In the current study, we employed a computer-based task, where participants control a spaceship and attempt to gain points by shooting an enemy spaceship that appears on the screen. Warning signals predict on-screen aversive events; the participants can learn a protective response to escape or avoid these events. This task has been recently used to reveal facilitated acquisition of avoidance behavior in individuals with anxiety vulnerability due to female sex or inhibited personality. Here, we extended the task to include an extinction phase, and tested the effect of signals that appeared during “safe” periods. Healthy young adults (n = 122) were randomly assigned to a testing condition with or without such signals. Results showed that the addition of safety signals during the acquisition phase impaired acquisition (in females) and facilitated extinction of the avoidance behavior. We also replicated our recent finding of an association between female sex and longer avoidance duration and further showed that females continued to demonstrate more avoidance behavior even on extinction trials when the aversive events no longer occurred. This study is the first to show sex differences on the acquisition and extinction of human avoidance behavior and to demonstrate the role of safety signals in such behavior, highlighting the potential relevance of safety signals for cognitive therapies that focus on extinction learning to treat anxiety symptoms. PMID:25309373
Pickell, Paul D; Coops, Nicholas C; Ferster, Colin J; Bater, Christopher W; Blouin, Karen D; Flannigan, Mike D; Zhang, Jinkai
2017-10-27
Spring represents the peak of human-caused wildfire events in populated boreal forests, resulting in catastrophic loss of property and human life. Human-caused wildfire risk is anticipated to increase in northern forests as fuels become drier, on average, under warming climate scenarios and as population density increases within formerly remote regions. We investigated springtime human-caused wildfire risk derived from satellite-observed vegetation greenness in the early part of the growing season, a period of increased ignition and wildfire spread potential from snow melt to vegetation green-up with the aim of developing an early warning wildfire risk system. The initial system was developed for 392,856 km 2 of forested lands with satellite observations available prior to the start of the official wildfire season and predicted peak human-caused wildfire activity with 10-day accuracy for 76% of wildfire-protected lands by March 22. The early warning system could have significant utility as a cost-effective solution for wildfire managers to prioritize the deployment of wildfire protection resources in wildfire-prone landscapes across boreal-dominated ecosystems of North America, Europe, and Russia using open access Earth observations.
Airborne Turbulence Detection and Warning ACLAIM Flight Test Results
NASA Technical Reports Server (NTRS)
Hannon, Stephen M.; Bagley, Hal R.; Soreide, Dave C.; Bowdle, David A.; Bogue, Rodney K.; Ehernberger, L. Jack
1999-01-01
The Airborne Coherent Lidar for Advanced Inflight Measurements (ACLAIM) is a NASA/Dryden-lead program to develop and demonstrate a 2 micrometers pulsed Doppler lidar for airborne look-ahead turbulence detection and warning. Advanced warning of approaching turbulence can significantly reduce injuries to passengers and crew aboard commercial airliners. The ACLAIM instrument is a key asset to the ongoing Turbulence component of NASA's Aviation Safety Program, aimed at reducing the accident rate aboard commercial airliners by a factor of five over the next ten years and by a factor of ten over the next twenty years. As well, the advanced turbulence warning capability can prevent "unstarts" in the inlet of supersonic aircraft engines by alerting the flight control computer which then adjusts the engine to operate in a less fuel efficient, and more turbulence tolerant, mode. Initial flight tests of the ACLAIM were completed in March and April of 1998. This paper and presentation gives results from these initial flights, with validated demonstration of Doppler lidar wind turbulence detection several kilometers ahead of the aircraft.
33 CFR 150.628 - How must the operator label, tag, and mark a container of hazardous material?
Code of Federal Regulations, 2010 CFR
2010-07-01
... Workplace Safety and Health Hazard Communication Program § 150.628 How must the operator label, tag, and..., reactive and other special condition hazard warnings. The only exception is for portable containers that...
Cost-benefit analysis of sequential warning lights in nighttime work zone tapers.
DOT National Transportation Integrated Search
2011-06-01
Improving safety at nighttime work zones is important because of the extra visibility concerns. The deployment of sequential lights is an innovative method for improving driver recognition of lane closures and work zone tapers. Sequential lights are ...
DOT National Transportation Integrated Search
2012-10-01
Active Traffic Management (ATM) applications, such as variable speed limits, queue warning systems, and dynamic : ramp metering, have been shown to offer mobility and safety benefits. Yet because they differ from conventional capacity : investments i...
Presenting hazard warning information to drivers using an advanced traveler information system
DOT National Transportation Integrated Search
1997-02-01
Although Advanced Traveler Information System (ATIS) devices have the potential to improve travel safety, efficiency, and comfort, they represent a new frontier in ground transportation. In order to realize this potential, they must be designed in a ...
So You Have a Diabetic in Your Classroom.
ERIC Educational Resources Information Center
Blake, Sue Baird
1984-01-01
To deal effectively with diabetic children, teachers need to learn as much as they can about the disease. This article discusses how diabetes affects the child, warning signals of diabetes, and precautions teachers can take to ensure the child's safety. (JMK)
In-Vehicle Safety Advisory And Warning System (Ivsaws), Volume II: Final Report
DOT National Transportation Integrated Search
2001-04-01
Methods for determining the workability of freshly mixed portland-cement concrete with slumps less than 51 mm (2 in) were investigated. Four potential methods to determine the workability of concrete were proposed for evaluation and development. The ...
21 CFR 874.3305 - Wireless air-conduction hearing aid.
Code of Federal Regulations, 2013 CFR
2013-04-01
...-amplifying device, intended to compensate for impaired hearing that incorporates wireless technology in its...: (1) Appropriate analysis/testing should validate electro magnetic compatibility (EMC) and safety of... technology functions; and (3) Labeling should specify appropriate instructions, warnings, and information...
Summary Report: Uniform Traffic Control And Warning Messages For Portable Changeable Message Signs
DOT National Transportation Integrated Search
2000-03-01
The California database incorporated in the Highway Safety Information System (HSIS) is derived from the California TASAS (Traffic Accident Surveillance and Analysis System). The system, maintained by the Traffic Operations Office of Caltrans, is a m...
Active Work Zone Safety Using Emerging Technologies : Final Report
DOT National Transportation Integrated Search
2017-07-01
The major objectives of this research were to (1) identify technologies that can be used in real time to detect a hazardous proximity situation between construction equipment and pedestrian workers and provide an appropriate warning; (2) develop a Bl...
Research on public participant urban infrastructure safety monitoring system using smartphone
NASA Astrophysics Data System (ADS)
Zhao, Xuefeng; Wang, Niannian; Ou, Jinping; Yu, Yan; Li, Mingchu
2017-04-01
Currently more and more people concerned about the safety of major public security. Public participant urban infrastructure safety monitoring and investigation has become a trend in the era of big data. In this paper, public participant urban infrastructure safety protection system based on smart phones is proposed. The system makes it possible to public participant disaster data collection, monitoring and emergency evaluation in the field of disaster prevention and mitigation. Function of the system is to monitor the structural acceleration, angle and other vibration information, and extract structural deformation and implement disaster emergency communications based on smartphone without network. The monitoring data is uploaded to the website to create urban safety information database. Then the system supports big data analysis processing, the structure safety assessment and city safety early warning.
The 1991 International Aerospace and Ground Conference on Lightning and Static Electricity, volume 1
NASA Technical Reports Server (NTRS)
1991-01-01
The proceedings of the 1991 International Aerospace and Ground Conference on Lightning and Static Electricity are reported. Some of the topics covered include: lightning, lightning suppression, aerospace vehicles, aircraft safety, flight safety, aviation meteorology, thunderstorms, atmospheric electricity, warning systems, weather forecasting, electromagnetic coupling, electrical measurement, electrostatics, aircraft hazards, flight hazards, meteorological parameters, cloud (meteorology), ground effect, electric currents, lightning equipment, electric fields, measuring instruments, electrical grounding, and aircraft instruments.